BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P26449 (341 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2I3T-A nrPDB 699 0.0 4OWR-A nrPDB 75 4e-14 6Q8F-A nrPDB 37 0.009 6HHQ-h nrPDB 36 0.019 6HQA-B nrPDB 35 0.045 3JAP-g nrPDB 35 0.064 5K1B-B nrPDB 34 0.072 6MZM-G nrPDB 34 0.083 6F3T-A nrPDB 34 0.086 5GAN-H nrPDB 33 0.17 1NR0-A nrPDB 33 0.26 5Y88-O nrPDB 32 0.31 5CXB-B nrPDB 32 0.40 5WYK-BB nrPDB 32 0.50 5I2T-A nrPDB 32 0.52 5WLC-LO nrPDB 32 0.58 4XYI-A nrPDB 31 0.69 6ID0-T nrPDB 31 0.84 6GMH-W nrPDB 31 0.98 4LG8-A nrPDB 30 1.0 5Z56-q nrPDB 30 1.1 4BTS-AR nrPDB 30 1.2 6EMK-B nrPDB 30 1.2 3I2N-A nrPDB 30 1.6 5WLC-LJ nrPDB 30 1.9 5XYI-g nrPDB 30 2.0 4J0X-A nrPDB 30 2.2 5OQL-J nrPDB 29 2.5 3DM0-A nrPDB 29 2.6 3I5P-A nrPDB 29 2.7 5WLC-SG nrPDB 29 2.7 4N3O-A nrPDB 29 2.7 3I5Q-B nrPDB 29 2.9 5MWJ-A nrPDB 29 3.0 5WYJ-BE nrPDB 29 3.1 5WLC-LN nrPDB 29 3.3 5FL8-q nrPDB 29 3.4 3LX2-A nrPDB 29 3.7 5M25-A nrPDB 28 4.6 5WLC-LU nrPDB 28 5.0 1VYH-C nrPDB 28 5.1 2H9P-A nrPDB 28 6.8 4YCZ-A nrPDB 28 6.9 1PI6-A nrPDB 28 7.0 5MMJ-y nrPDB 28 8.0 >2I3T-A nrPDB Length = 341 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/341 (100%), Positives = 341/341 (100%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL Sbjct: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW Sbjct: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC Sbjct: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC Sbjct: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 Query: 241 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI Sbjct: 241 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 Query: 301 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN 341 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN Sbjct: 301 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN 341 >4OWR-A nrPDB Length = 339 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 31/327 (9%) Query: 4 VQIEQAPKDYISDIKIIPSK---SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +++ +P D I + P + L+ SW + ++ + + Q + L Sbjct: 3 IEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLD 62 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 C D + +++ + DL + + Q ++ I I ++ SW Sbjct: 63 VCWSDDGS--KVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSW 120 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 D ++ D R+ ++ V + + T LIV +Q FR Sbjct: 121 DKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRR--- 177 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQE---GYACSSIDGRVAVEFFDDQGDDYNSSK-RF 236 ES LK+Q R VA+ +Q G+A SI+GRVA+ + + N +K F Sbjct: 178 -------IESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPP----NPAKDNF 226 Query: 237 AFRCHRLNLKDTNLA---YPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFN 293 F+CHR N +T+ Y VN I F P H L T GSDG S W+ R K+K + Sbjct: 227 TFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQL- 285 Query: 294 EDSVVKIAC---SDNILCLATSDDTFK 317 D + C + NI A+S D K Sbjct: 286 -DQPISACCFNHNGNIFAYASSYDWSK 311 >6Q8F-A nrPDB Length = 514 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 20/127 (15%) Query: 191 GLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSK--RFAFRCHRLNLKDT 248 LK+Q + LLP G G+ AV+ +++ S+ +F + H Sbjct: 169 ALKWQ-QHQGLLPP---GMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSH------- 217 Query: 249 NLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILC 308 V FSP ++L T DG I WN T K K+ +D+ + + D +LC Sbjct: 218 -----VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMM--DDAVLC 270 Query: 309 LATSDDT 315 + S DT Sbjct: 271 MCFSRDT 277 Score = 34.7 bits (78), Expect = 0.056, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 10/73 (13%) Query: 259 FSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFKT 318 FS + L T DG I W +Q+ + ++ F + A S + CL+ S D+ + Sbjct: 273 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFER---------AHSKGVTCLSFSKDSSQI 323 Query: 319 -NAAIDQTIELNA 330 +A+ DQTI ++ Sbjct: 324 LSASFDQTIRIHG 336 Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust. Identities = 63/320 (19%), Positives = 120/320 (37%), Gaps = 39/320 (12%) Query: 5 QIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQS-----LRYKHPL 59 I+ K ++ + P L+ S DG + V+ F DL + + Sbjct: 209 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAV 268 Query: 60 LCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAAS 119 LC F +T++ + G G+I + + + C ++++AS Sbjct: 269 LCMCFSRDTEM-LATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 327 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPL 179 +D I + ++ +K +++ V FT D + +I ++ V+ + + Sbjct: 328 FDQTIRIHGLKSGK----TLKEFRGHSSFVNEATFTQDGH--YIISASSDGTVKIWNMKT 381 Query: 180 CEDDN---GTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGD---DYNSS 233 E N +G + V LLPK E + + V + + QG ++S Sbjct: 382 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVI--MNMQGQIVRSFSSG 439 Query: 234 KRFA--FRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAK 291 KR F C L SPR +++Y G D ++ C++ T K++ Sbjct: 440 KREGGDFVCCAL----------------SPRGEWIYCVGEDFVLYCFSTVT-GKLERTLT 482 Query: 292 FNEDSVVKIACSDNILCLAT 311 +E V+ IA + +AT Sbjct: 483 VHEKDVIGIAHHPHQNLIAT 502 >6HHQ-h nrPDB Length = 319 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 +N++ SP + +AG DG I WNL +K + + +D V +A S N LA + Sbjct: 199 INTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSA--QDEVFSLAFSPNRYWLAAAT 256 Query: 314 DT 315 T Sbjct: 257 AT 258 >6HQA-B nrPDB Length = 722 Score = 35.0 bits (79), Expect = 0.045, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 30/59 (50%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATS 312 +N + SP ++L +AG D ++ W++ T ++IK S+ +A S L ++ Sbjct: 582 INCLAVSPDGRWLASAGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVST 640 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 10/61 (16%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 V+ +EF P +L+T SD W++ + ++ F + S I CLA S Sbjct: 540 VDCVEFHPNSTYLFTGSSDKTARMWDIARGECVRVF----------MGHSGAINCLAVSP 589 Query: 314 D 314 D Sbjct: 590 D 590 >3JAP-g nrPDB Length = 326 Score = 34.7 bits (78), Expect = 0.064, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 19/88 (21%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 +N ++ SP +AG DG I WNL+ + NF D + LA S Sbjct: 206 INVVQPSPDGSLAASAGKDGQIYVWNLKHKSAFMNF-----------DAKDEVFALAFSP 254 Query: 314 DTFKTNAAIDQTIELNASSIYIIFDYEN 341 F AA I+ I+D EN Sbjct: 255 SRFWLTAATASGIK--------IYDLEN 274 >5K1B-B nrPDB Length = 677 Score = 34.3 bits (77), Expect = 0.072, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDS----VVKIACSDNILCL 309 VN+++ P L+TAG D II W++ K+ A + + + C+ L Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 310 ATSDDTFK 317 A+SD T K Sbjct: 93 ASSDTTVK 100 >6MZM-G nrPDB Length = 800 Score = 34.3 bits (77), Expect = 0.083, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDN--ILCLA 310 P++S+ FSP +FL T +DG + W++ + K + D+V + S + IL Sbjct: 671 PIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGEL-KGHTDTVCSLRFSRDGEILASG 729 Query: 311 TSDDTFKTNAAI 322 + D+T + AI Sbjct: 730 SMDNTVRLWDAI 741 Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQT 282 PV FSP +L ++ DG + W+LQT Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQT 574 >6F3T-A nrPDB Length = 608 Score = 34.3 bits (77), Expect = 0.086, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDN--ILCLA 310 P++S+ FSP +FL T +DG + W++ + K + D+V + S + IL Sbjct: 479 PIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGEL-KGHTDTVCSLRFSRDGEILASG 537 Query: 311 TSDDTFKTNAAI 322 + D+T + AI Sbjct: 538 SMDNTVRLWDAI 549 Score = 32.0 bits (71), Expect = 0.40, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQT 282 PV FSP +L ++ DG + W+LQT Sbjct: 353 PVYGASFSPDRNYLLSSSEDGTVRLWSLQT 382 >5GAN-H nrPDB Length = 465 Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust. Identities = 21/87 (24%), Positives = 42/87 (48%), Gaps = 14/87 (16%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTR-----------KKIKNFAKFNEDSVVK-- 299 P+ ++ +SP + T G DGII+ W+++ R + I +F+++ K Sbjct: 351 PIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKL 410 Query: 300 IACS-DNILCLATSDDTFKTNAAIDQT 325 ++C DN++ + +SD K + T Sbjct: 411 VSCGYDNLINVYSSDTWLKMGSLAGHT 437 >1NR0-A nrPDB Length = 611 Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 V+S+ ++P + G DG I +N K F +DS+ +A S ++ L S Sbjct: 193 VHSVRYNPDGSLFASTGGDGTIVLYNGVDGTKT---GVFEDDSLKNVAHSGSVFGLTWSP 249 Query: 314 DTFK-TNAAIDQTIEL 328 D K +A+ D+TI++ Sbjct: 250 DGTKIASASADKTIKI 265 >5Y88-O nrPDB Length = 451 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKN-FAKFNEDSVVKIACSDNILCLATS 312 V + S RH +L++ D + CW+L+ + I++ + + V I + +++ A Sbjct: 185 VRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGR 244 Query: 313 DDTFK 317 D K Sbjct: 245 DSVIK 249 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 17/91 (18%), Positives = 42/91 (46%), Gaps = 10/91 (10%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNL----------QTRKKIKNFAKFNEDSVVKIAC 302 P+N ++ +P + ++ +D + W++ ++ ++ A ++ V AC Sbjct: 268 PINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASAC 327 Query: 303 SDNILCLATSDDTFKTNAAIDQTIELNASSI 333 +D+I ++ + TN ++T +N SI Sbjct: 328 TDDIRSWGLAEGSLLTNFESEKTGIINTLSI 358 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 10/30 (33%), Positives = 17/30 (56%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTR 283 V ++ P + TAG D +I W+++TR Sbjct: 227 VRTVSIHPTLDLIATAGRDSVIKLWDMRTR 256 >5CXB-B nrPDB Length = 369 Score = 32.0 bits (71), Expect = 0.40, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 V S+ P L T G DG + W L T +++ + K N D V N + + Sbjct: 24 VRSVAIDPTGVALATGGDDGTVRVWELLTGRQVWS-VKLNGDEAV------NTVRWRPTK 76 Query: 314 DTFKTNAAIDQTIEL 328 DTF AA + I L Sbjct: 77 DTFILAAAAGEDIFL 91 >5WYK-BB nrPDB Length = 943 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 6/108 (5%) Query: 25 LLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEILKV 84 LL + DG + V+ D+ +K V LL +K + F D T ++ G+ I+ Sbjct: 93 LLAVGYADGVIKVW--DLMSKTV-LLNFNGHKAAITLLQF-DGTGTRLISGSKDSNIIVW 148 Query: 85 DLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNY 132 DL+G L +++ + I G+D LI+ S DG+I++ D + + Sbjct: 149 DLVGEVGLYKLRSHKDS--ITGFWCQGEDWLISTSKDGMIKLWDLKTH 194 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 V SI+ S +K L TA S+G + WN++T K I+ F Sbjct: 394 VRSIDISDDNKLLATA-SNGSLKIWNIKTHKCIRTF 428 >5I2T-A nrPDB Length = 742 Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC-----SDNILC 308 V +++F+ R + ++++ DG + W+L + +NF F ++ C S ++C Sbjct: 415 VTAVQFAKRGQVMFSSSLDGTVRAWDL---IRYRNFRTFTGTERIQFNCLAVDPSGEVVC 471 Query: 309 LATSDDTFKTNAAIDQTIEL 328 A S D F + QT +L Sbjct: 472 -AGSLDNFDIHVWSVQTGQL 490 >5WLC-LO nrPDB Length = 923 Score = 31.6 bits (70), Expect = 0.58, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC-----SDNILC 308 V +++F+ R + ++++ DG + W+L + +NF F ++ C S ++C Sbjct: 390 VTAVQFAKRGQVMFSSSLDGTVRAWDL---IRYRNFRTFTGTERIQFNCLAVDPSGEVVC 446 Query: 309 LATSDDTFKTNAAIDQTIEL 328 A S D F + QT +L Sbjct: 447 -AGSLDNFDIHVWSVQTGQL 465 >4XYI-A nrPDB Length = 430 Score = 31.2 bits (69), Expect = 0.69, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 4/65 (6%) Query: 253 PVNSIEFSPRHKFLY-TAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDN---ILC 308 PVN + F+P + +L TA +D ++ W+L+ + + + +ED V + S + IL Sbjct: 283 PVNGVAFNPFNDYLLATASADHTVALWDLRRLNQRLHTLEGHEDEVYNVQWSPHDEPILV 342 Query: 309 LATSD 313 +++D Sbjct: 343 TSSTD 347 >6ID0-T nrPDB Length = 514 Score = 30.8 bits (68), Expect = 0.84, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 25/48 (52%) Query: 242 RLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 +L L T V + S R +L++ G D + CW+L+ K I+++ Sbjct: 237 KLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHY 284 >6GMH-W nrPDB Length = 305 Score = 30.8 bits (68), Expect = 0.98, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 251 AYPVNSIEFSPRHKFLYTAGSDGIISCWNLQ 281 A P+ S+ FSP + L TA DG I +++Q Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ 220 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 9/59 (15%) Query: 256 SIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFA---------KFNEDSVVKIACSDN 305 SI +SP K+L + DGII+ +++ T K + F+ DS + + SD+ Sbjct: 153 SIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDD 211 >4LG8-A nrPDB Length = 354 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 258 EFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDD 314 +F P T D I W+L+ R + NF + + IA S+N LAT+ D Sbjct: 207 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLATAAD 262 >5Z56-q nrPDB Length = 504 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 258 EFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDD 314 +F P T D I W+L+ R + NF + + IA S+N LAT+ D Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLATAAD 412 >4BTS-AR nrPDB Length = 343 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 28/172 (16%) Query: 116 IAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWF 175 I++SWD + + D R K + ++V + F+ D N L G W Sbjct: 92 ISSSWDKTLRLWDLRT----GTTYKRFVGHQSEVYSVAFSPD-NRQILSAGAEREIKLWN 146 Query: 176 RLPLC-----EDDNGTIEESGLKYQ--IRDVALLPKEQEGYACSSIDGRVAVEFFDDQGD 228 L C E +N + S ++Y ++ + +A DGR+ V Sbjct: 147 ILGECKFSSAEKENHSDWVSCVRYSPIMKSANKVQPFAPYFASVGWDGRLKVW------- 199 Query: 229 DYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNL 280 + N R+ F+ H N VN + SP K++ T G D + W++ Sbjct: 200 NTNFQIRYTFKAHESN---------VNHLSISPNGKYIATGGKDKKLLIWDI 242 >6EMK-B nrPDB Length = 303 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 259 FSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSV 297 FS +L TA SD + W+L TR+ ++ + ++ +V Sbjct: 258 FSADSAYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAV 296 >3I2N-A nrPDB Length = 357 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 32/156 (20%), Positives = 64/156 (41%), Gaps = 10/156 (6%) Query: 3 IVQIEQAPKDYISDIKIIP--SKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 I I++ + D K +P +K + + G+ + ++IQ ++ LL+ + P+ Sbjct: 10 IAHIQKGFNYTVFDCKWVPCSAKFVTMGNFARGTGVIQLYEIQHGDLKLLREIEKAKPIK 69 Query: 61 CCNFIDNTDLQIYVGTVQ-GEILKVDLIGSPSFQALTN-------NEANLGICRICKYGD 112 C F + Q Y+ T G L + + +P + N + G Sbjct: 70 CGTFGATSLQQRYLATGDFGGNLHIWNLEAPEMPVYSVKGHKEIINAIDGIGGLGIGEGA 129 Query: 113 DKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTK 148 +++ S DG ++V DPR D V ++ + N + Sbjct: 130 PEIVTGSRDGTVKVWDPRQKDDPVANMEPVQGENKR 165 >5WLC-LJ nrPDB Length = 513 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 41/86 (47%), Gaps = 10/86 (11%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNE-------DSVVKIACSDNI 306 V I F+P+H + S + ++ +TR+ IK F++F + S K+ C+ + Sbjct: 42 VTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDA 101 Query: 307 LCLATSDDTFKTNAAIDQTIELNASS 332 L + D++ + + +NAS+ Sbjct: 102 TGLVSVYDSYNPRTIL---LSINAST 124 Score = 27.7 bits (60), Expect = 7.9, Method: Compositional matrix adjust. Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 12/124 (9%) Query: 12 DYISDIKIIPSKSLLLIT-SWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDL 70 DY+ + IP+ L+ T S+DG + +Y D ++ + SL + P+ N I + Sbjct: 169 DYVRTLSFIPAAPHLVATGSYDGLIRLY--DTRSSGSTPIYSLNHDQPV--ENVIAVSPT 224 Query: 71 QIYVGTVQGEILKV-DLIGSPSFQALTN-NEANLGICRICKYG---DDKLIAASWDGLIE 125 QI + G KV DL + N N+A + + + LIA+S DG ++ Sbjct: 225 QIV--SCGGNNFKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVK 282 Query: 126 VIDP 129 V DP Sbjct: 283 VFDP 286 >5XYI-g nrPDB Length = 335 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/74 (24%), Positives = 32/74 (43%) Query: 255 NSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDD 314 S++F+P K++ T GSD + W + K +F + V + +C AT + Sbjct: 214 TSVDFTPDGKWVITGGSDRKVVMWLTENGAKTISFTAPSPVHAVAACPTQAWICAATYEG 273 Query: 315 TFKTNAAIDQTIEL 328 + Q I+L Sbjct: 274 IAVWDIGAKQQIDL 287 >4J0X-A nrPDB Length = 451 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL 53 +I+ + IP ++ + SW GSL V+K ++ +LL L Sbjct: 352 WITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGEL 392 >5OQL-J nrPDB Length = 912 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 5/60 (8%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKI--KNFAKFNED---SVVKIACSDNILC 308 + S+ F K++Y+AG+ G++ W+ T +I K AK + S V + ILC Sbjct: 277 LESVGFLNEGKWMYSAGTSGVLRIWDTTTHHEITKKQDAKSEGEAILSAVSLPERSLILC 336 >3DM0-A nrPDB Length = 694 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC-SDN--ILCLA 310 V+++ SP + G DG++ W+L KK+ + +SV+ C S N LC A Sbjct: 564 VSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYS---LEANSVIHALCFSPNRYWLCAA 620 Query: 311 T 311 T Sbjct: 621 T 621 >3I5P-A nrPDB Length = 525 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 27/52 (51%) Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE 125 + T+ G+IL + + L+ +E L I +I + D ++I A WD L + Sbjct: 317 IKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQ 368 >5WLC-SG nrPDB Length = 573 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL 53 +I+ + IP ++ + SW GSL V+K ++ +LL L Sbjct: 474 WITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGEL 514 >4N3O-A nrPDB Length = 342 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Query: 163 LIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQI--RDVALLPKEQEGYACSSIDGRVAV 220 L+VG+ + +W LPL G E + L Y+I D+ ++ Q+ YA ++ G + Sbjct: 122 LVVGVIKAFAEWLNLPL-----GEYEIAKLAYEIEREDLGIVGGAQDQYA-ATFGGFNFM 175 Query: 221 EFFDDQ 226 EF++++ Sbjct: 176 EFYNNK 181 >3I5Q-B nrPDB Length = 252 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 27/52 (51%) Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE 125 + T+ G+IL + + L+ +E L I +I + D ++I A WD L + Sbjct: 44 IKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQ 95 >5MWJ-A nrPDB Length = 337 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 11/87 (12%) Query: 242 RLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA 301 R+ + T+ A ++ SP K ++ SDG I+ W+L + ++ F Sbjct: 132 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGH--------- 182 Query: 302 CSDNILCLATSDDTFKT-NAAIDQTIE 327 +D C+ S+D K +D T+ Sbjct: 183 -TDGASCIDISNDGTKLWTGGLDNTVR 208 >5WYJ-BE nrPDB Length = 939 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 10/75 (13%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF--------AKF--NEDSVVKIACS 303 + + +FSP +++ +A D I W+L T I KF N D + + Sbjct: 588 ITAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGIIVDNVATNVKFSPNGDLLATTHVT 647 Query: 304 DNILCLATSDDTFKT 318 N +C+ T+ FKT Sbjct: 648 GNGICIWTNRAQFKT 662 >5WLC-LN nrPDB Length = 776 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 16/136 (11%) Query: 192 LKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLA 251 ++ + R + L K+ + DGR+ + + Q +D N + K++ L Sbjct: 184 MRQEARVLTLAWKKDDFVIGGCSDGRIRI--WSAQKNDENMGRLLHTMKVDKAKKESTLV 241 Query: 252 YPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLAT 311 + S+ + PR + + S G I W+ Q FA N+ A ++LCL T Sbjct: 242 W---SVIYLPRTDQIASGDSTGSIKFWDFQ-------FATLNQSFKAHDA---DVLCLTT 288 Query: 312 -SDDTFKTNAAIDQTI 326 +D+ + +A +D+ I Sbjct: 289 DTDNNYVFSAGVDRKI 304 >5FL8-q nrPDB Length = 515 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA-CSDNILCLATS 312 VN + FSP +++ +A D I W+ + K I F + + SV ++A SD L ++ S Sbjct: 405 VNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTF-RGHVASVYQVAWSSDCRLLVSCS 463 Query: 313 DDT 315 DT Sbjct: 464 KDT 466 >3LX2-A nrPDB Length = 259 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 163 LIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVAL 201 L VG+ + WF+LPL + + IE L + ++ V L Sbjct: 99 LEVGLLGDENTWFKLPLIDANTPEIEIPSLPWTVKAVVL 137 >5M25-A nrPDB Length = 434 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 11/67 (16%) Query: 264 KFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC--SDNILCLATSDDTFKTNAA 321 K++ + D ++ WNLQT++ ++ + + D V+ AC ++NI+ A ++ Sbjct: 372 KWIVSGSEDNLVYIWNLQTKEIVQKL-QGHTDVVISTACHPTENIIASAALEN------- 423 Query: 322 IDQTIEL 328 D+TI+L Sbjct: 424 -DKTIKL 429 Score = 27.7 bits (60), Expect = 8.2, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 20/37 (54%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 PV+ ++FSP K++ A D + W+ K +K + Sbjct: 316 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 352 >5WLC-LU nrPDB Length = 489 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 16/24 (66%) Query: 266 LYTAGSDGIISCWNLQTRKKIKNF 289 L T +DG+I WN+ TR++ +F Sbjct: 83 LATGSADGVIKYWNMSTREEFVSF 106 >1VYH-C nrPDB Length = 410 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 29/127 (22%), Positives = 50/127 (39%), Gaps = 24/127 (18%) Query: 189 ESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHR-LNLKD 247 E LK V + + G +S + ++ +D QG F C R ++ D Sbjct: 143 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG----------FECIRTMHGHD 192 Query: 248 TNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFA---------KFNEDSVV 298 N V+S+ P + +A D I W +QT +K F + N+D + Sbjct: 193 HN----VSSVSIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTL 248 Query: 299 KIACSDN 305 +CS++ Sbjct: 249 IASCSND 255 >2H9P-A nrPDB Length = 329 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 11/67 (16%) Query: 264 KFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC--SDNILCLATSDDTFKTNAA 321 K++ + D ++ WNLQT++ ++ + + D V+ AC ++NI+ A ++ Sbjct: 267 KWIVSGSEDNLVYIWNLQTKEIVQKL-QGHTDVVISTACHPTENIIASAALEN------- 318 Query: 322 IDQTIEL 328 D+TI+L Sbjct: 319 -DKTIKL 324 Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 20/37 (54%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 PV+ ++FSP K++ A D + W+ K +K + Sbjct: 211 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 247 >4YCZ-A nrPDB Length = 876 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 22/134 (16%) Query: 210 ACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLA---YPVNSIEFSPRHKF- 265 AC+S DG V+V F D NS + F H L + + A P + + P K Sbjct: 126 ACASSDGNVSVLEFRD-----NSWEHSIFHAHGLGVNSVSWAPATSPGSIVSSKPGPKST 180 Query: 266 ----LYTAGSDGIISCWNL----QTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFK 317 T GSD + W T K + + D V +A S +L ++ Sbjct: 181 GNRRFVTGGSDNALKIWAYDPATNTYKLEREPLTGHTDWVRDVAWSPTVL-----QKSYI 235 Query: 318 TNAAIDQTIELNAS 331 +A+ D+T+ + S Sbjct: 236 ASASEDRTVRIWTS 249 >1PI6-A nrPDB Length = 615 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 5/43 (11%) Query: 254 VNSIEFSP-RHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNED 295 V +EFSP +F+ T GSD ISC++ K F K+ ED Sbjct: 209 VRDVEFSPDSGEFVITVGSDRKISCFD----GKSGEFLKYIED 247 >5MMJ-y nrPDB Length = 302 Score = 27.7 bits (60), Expect = 8.0, Method: Compositional matrix adjust. Identities = 11/41 (26%), Positives = 25/41 (60%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLR 54 + ++I +K ++ SWDG L+ K +Q +N+++ ++R Sbjct: 51 VKSVQISRNKPNVVCMSWDGPLSSVKLILQGRNLEVSDNVR 91 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2I3T-A nrPDB 565 e-162 4OWR-A nrPDB 463 e-131 Sequences not found previously or not previously below threshold: 6Q8F-A nrPDB 58 6e-09 6G51-g nrPDB 57 1e-08 4V6W-Ag nrPDB 56 3e-08 3DM0-A nrPDB 56 3e-08 5GAN-H nrPDB 54 7e-08 5M25-A nrPDB 54 1e-07 2HES-X nrPDB 53 2e-07 2H9P-A nrPDB 52 3e-07 5NZU-C nrPDB 52 3e-07 6QX9-5O nrPDB 52 3e-07 5FL8-q nrPDB 52 5e-07 6CHG-A nrPDB 49 2e-06 5NNZ-B nrPDB 49 3e-06 3I2N-A nrPDB 49 3e-06 4V8M-A7 nrPDB 49 4e-06 3JB9-g nrPDB 49 4e-06 5OPT-p nrPDB 48 6e-06 6EOJ-D nrPDB 47 9e-06 3MKQ-A nrPDB 45 3e-05 6QDV-o nrPDB 45 4e-05 5YZG-W nrPDB 45 4e-05 2YNP-A nrPDB 45 4e-05 6N9G-C nrPDB 45 5e-05 5MZH-A nrPDB 45 5e-05 5WYK-BB nrPDB 45 6e-05 5WLC-LJ nrPDB 45 6e-05 3JB9-L nrPDB 44 7e-05 4BTS-AR nrPDB 44 9e-05 4V7E-Bg nrPDB 43 1e-04 5XYI-g nrPDB 43 2e-04 1VYH-C nrPDB 42 3e-04 6ELZ-p nrPDB 42 3e-04 5OQL-L nrPDB 42 3e-04 6MZM-G nrPDB 42 4e-04 6F3T-A nrPDB 42 4e-04 5Y88-O nrPDB 41 6e-04 6QX9-4B nrPDB 41 6e-04 3JAP-g nrPDB 41 7e-04 4AEZ-A nrPDB 41 8e-04 5WLC-LS nrPDB 41 8e-04 5Z56-q nrPDB 41 8e-04 3FM0-A nrPDB 40 0.001 6HQA-B nrPDB 40 0.001 4LG8-A nrPDB 40 0.001 6EMK-B nrPDB 40 0.001 3W15-A nrPDB 40 0.002 5WYJ-BC nrPDB 39 0.002 6BX3-B nrPDB 39 0.003 5WLC-LO nrPDB 39 0.003 5I2T-A nrPDB 39 0.003 5FVM-C nrPDB 39 0.004 5UZ7-B nrPDB 39 0.004 5K0Y-T nrPDB 38 0.005 4A11-B nrPDB 38 0.005 4L9O-A nrPDB 38 0.006 5OQL-d nrPDB 38 0.007 6CHG-D nrPDB 37 0.009 5K1B-B nrPDB 37 0.015 4J0X-A nrPDB 37 0.015 3ACP-A nrPDB 37 0.016 5WLC-SG nrPDB 36 0.018 3BG0-A nrPDB 36 0.019 1NR0-A nrPDB 36 0.023 6HHQ-h nrPDB 36 0.023 6GMH-W nrPDB 36 0.024 6BX3-A nrPDB 36 0.025 5WLC-LU nrPDB 36 0.026 5M89-A nrPDB 35 0.031 5OQL-J nrPDB 35 0.033 6ID0-T nrPDB 35 0.045 5WLC-LN nrPDB 35 0.057 5YZG-2 nrPDB 34 0.11 6J6H-n nrPDB 34 0.13 5US9-A nrPDB 34 0.13 5K19-A nrPDB 34 0.15 1PI6-A nrPDB 33 0.19 4XFV-A nrPDB 33 0.20 4XYI-A nrPDB 33 0.24 5LCW-Q nrPDB 32 0.30 4GGA-A nrPDB 32 0.32 5G04-R nrPDB 32 0.32 5MC6-j nrPDB 32 0.37 4N14-A nrPDB 32 0.38 4G56-B nrPDB 32 0.41 3ODT-A nrPDB 32 0.45 5CXB-B nrPDB 31 0.74 5N4A-A nrPDB 31 0.81 3F3P-A nrPDB 31 0.90 5MWJ-A nrPDB 30 0.97 3EI3-B nrPDB 30 1.0 5OQL-X nrPDB 30 1.0 2AJB-A nrPDB 30 1.4 5WYJ-BE nrPDB 30 1.8 6CVZ-A nrPDB 30 1.9 3C9C-A nrPDB 30 1.9 6F1U-h nrPDB 30 1.9 5Y1U-A nrPDB 30 2.0 3CFV-B nrPDB 30 2.1 5WLC-LW nrPDB 29 2.5 5WBU-D nrPDB 29 3.3 3IH9-A nrPDB 29 4.5 4X33-B nrPDB 29 4.5 4D4O-A nrPDB 29 4.5 5CXC-A nrPDB 28 4.8 5WJC-A nrPDB 28 7.6 2OLS-A nrPDB 27 9.3 >2I3T-A nrPDB Length = 341 Score = 565 bits (1457), Expect = e-162, Method: Composition-based stats. Identities = 341/341 (100%), Positives = 341/341 (100%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL Sbjct: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW Sbjct: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC Sbjct: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC Sbjct: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 Query: 241 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI Sbjct: 241 HRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 Query: 301 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN 341 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN Sbjct: 301 ACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN 341 >4OWR-A nrPDB Length = 339 Score = 463 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 31/327 (9%) Query: 4 VQIEQAPKDYISDIKIIPSK---SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +++ +P D I + P + L+ SW + ++ + + Q + L Sbjct: 3 IEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLD 62 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 C D + +++ + DL + + Q ++ I I ++ SW Sbjct: 63 VCWSDDGS--KVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSW 120 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 D ++ D R+ ++ V + + T LIV +Q FR Sbjct: 121 DKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRR--- 177 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQE---GYACSSIDGRVAVEFFDDQGDDYNSSK-RF 236 ES LK+Q R VA+ +Q G+A SI+GRVA+ + + N +K F Sbjct: 178 -------IESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPP----NPAKDNF 226 Query: 237 AFRCHRLNLKDTNLA---YPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFN 293 F+CHR N +T+ Y VN I F P H L T GSDG S W+ R K+K + Sbjct: 227 TFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQL- 285 Query: 294 EDSVVKIAC---SDNILCLATSDDTFK 317 D + C + NI A+S D K Sbjct: 286 -DQPISACCFNHNGNIFAYASSYDWSK 311 >6Q8F-A nrPDB Length = 514 Score = 57.8 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 42/273 (15%), Positives = 85/273 (31%), Gaps = 30/273 (10%) Query: 11 KDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDL 70 D + + +L + DG + V+K + + + K D++ Sbjct: 265 DDAVLCMCFSRDTEMLATGAQDGKIKVWKIQ-SGQCLRRFERAHSKGVTCLSFSKDSS-- 321 Query: 71 QIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 QI + I L + + + + + + G +I+AS DG +++ + + Sbjct: 322 QILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGH-YIISASSDGTVKIWNMK 380 Query: 131 NYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEES 190 SN K D + +I+ + F +C N + + Sbjct: 381 TT---------ECSNTFKSLGSTAGTDITVNSVIL--LPKNPEHF--VVCNRSNTVVIMN 427 Query: 191 GLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCH-----RLNL 245 +R + +E + C ++ R Y + F C +L Sbjct: 428 MQGQIVRSFSSGKREGGDFVCCALSPR--------GEWIYCVGEDFVLYCFSTVTGKLER 479 Query: 246 KDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCW 278 T V I P + T DG++ W Sbjct: 480 TLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLW 512 Score = 27.4 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 36/98 (36%), Gaps = 5/98 (5%) Query: 215 DGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYP-----VNSIEFSPRHKFLYTA 269 G + F D ++S R H L T + VN F+ ++ +A Sbjct: 309 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISA 368 Query: 270 GSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNIL 307 SDG + WN++T + F + I + IL Sbjct: 369 SSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 406 >6G51-g nrPDB Length = 317 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 48/121 (39%), Gaps = 6/121 (4%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++SD+ I L SWDG+L ++ D+ K L DN QI Sbjct: 65 FVSDVVISSDGQFALSGSWDGTLRLW--DLTTGTTTRRFVGHTKDVLSVAFSSDN--RQI 120 Query: 73 YVGTVQGEILKVDLIG--SPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 G+ I + +G + Q +++E + + +++ WD L++V + Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180 Query: 131 N 131 N Sbjct: 181 N 181 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 46/108 (42%), Gaps = 4/108 (3%) Query: 24 SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI-YVGTVQGEIL 82 ++L S D ++ ++K N + Q H + + ++D Q G+ G + Sbjct: 29 DMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLR 88 Query: 83 KVDLI-GSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP 129 DL G+ + + + + + L + + ++++ S D I++ + Sbjct: 89 LWDLTTGTTTRRFVGHTKDVLSVAF--SSDNRQIVSGSRDKTIKLWNT 134 Score = 35.5 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 17/124 (13%), Positives = 39/124 (31%), Gaps = 9/124 (7%) Query: 7 EQAPKDYISDIKIIPSKSLLLITS--WDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNF 64 +++ +++S ++ P+ S +I S WD + V+ + + + Sbjct: 144 DESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG--HTGYLNTVTVS 201 Query: 65 IDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLI 124 D + G G+ + DL L + +C I Sbjct: 202 PDGSLCA--SGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGP---SI 256 Query: 125 EVID 128 ++ D Sbjct: 257 KIWD 260 >4V6W-Ag nrPDB Length = 318 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 42/121 (34%), Gaps = 6/121 (4%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 +ISD+ + + L SWD +L ++ K + K L DN QI Sbjct: 66 FISDVVLSSDGNYALSGSWDQTLRLWDLA-AGKTTRRFEG-HTKDVLSVAFSADN--RQI 121 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDK--LIAASWDGLIEVIDPR 130 G+ I + + F + + C +++ WD ++V + Sbjct: 122 VSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLA 181 Query: 131 N 131 N Sbjct: 182 N 182 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 44/122 (36%), Gaps = 15/122 (12%) Query: 12 DYISDIKIIPSKSLLLITS--WDGSLTVYKFDIQAKNVDLLQSLRYKH---PLLCCNFID 66 D++S ++ P+ S +I S WD ++ V+ L++ + H D Sbjct: 150 DWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC-----KLKNNHHGHNGYLNTVTVSPD 204 Query: 67 NTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEV 126 + G + L DL + L +N+ +C + ++ I++ Sbjct: 205 GSLCT--SGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCV---AYGPSIKI 259 Query: 127 ID 128 D Sbjct: 260 WD 261 Score = 32.4 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 40/251 (15%), Positives = 75/251 (29%), Gaps = 37/251 (14%) Query: 72 IYVGTVQGEILKVDLI-------GSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLI 124 I + ++ L G P + ++ + ++ SWD + Sbjct: 31 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYA--LSGSWDQTL 88 Query: 125 EVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDN 184 + D + A K K+ + + +R IV + + L E Sbjct: 89 RLWD-------LAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC-K 140 Query: 185 GTIEESGLKYQIRDVALLPKEQEGY--ACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHR 242 TI+E G + V P +C +D +N + C Sbjct: 141 FTIQEDGHTDWVSCVRFSPNHSNPIIVSCG----------WDRTVKVWNLAN-----CKL 185 Query: 243 LNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC 302 N + Y +N++ SP + G D W+L K + + D + + Sbjct: 186 KNNHHGHNGY-LNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE--HNDIINALCF 242 Query: 303 SDNILCLATSD 313 S N L + Sbjct: 243 SPNRYWLCVAY 253 >3DM0-A nrPDB Length = 694 Score = 55.5 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 42/125 (33%), Gaps = 12/125 (9%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ D+ + L SWDG L ++ + K L +DN QI Sbjct: 432 FVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVG--HTKDVLSVAFSLDN--RQI 487 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDD------KLIAASWDGLIEV 126 + I + +G + E + + +++ASWD ++V Sbjct: 488 VSASRDRTIKLWNTLGECKYTISEGGEGHRD--WVSCVRFSPNTLQPTIVSASWDKTVKV 545 Query: 127 IDPRN 131 + N Sbjct: 546 WNLSN 550 Score = 48.2 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 11/124 (8%) Query: 11 KDYISDIKIIPSK--SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNT 68 +D++S ++ P+ ++ SWD ++ V+ L + D + Sbjct: 517 RDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAG--HTGYVSTVAVSPDGS 574 Query: 69 DLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRIC-KYGDDKLIAASWDGLIEVI 127 G G +L DL +L EAN I +C L AA+ G I++ Sbjct: 575 LCA--SGGKDGVVLLWDLAEGKKLYSL---EANSVIHALCFSPNRYWLCAATEHG-IKIW 628 Query: 128 DPRN 131 D + Sbjct: 629 DLES 632 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 51/272 (18%), Positives = 89/272 (32%), Gaps = 41/272 (15%) Query: 54 RYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLI-GSPSFQALT-----NNEANLGICRI 107 IDN D+ I + I+ L ++ ++ + + Sbjct: 381 HTDMVTAIATPIDNADI-IVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDV--V 437 Query: 108 CKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGM 167 ++ SWDG + + D + A + K+ + + +R IV Sbjct: 438 LSSDGQFALSGSWDGELRLWD-------LAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSA 490 Query: 168 NNSQVQWFRLPLCEDDNGTIEESGLKYQ--IRDVALLPKE-QEGYACSSIDGRVAVEFFD 224 + + L E TI E G ++ + V P Q +S D V V Sbjct: 491 SRDRTIKLWNTLGECKY-TISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKV---- 545 Query: 225 DQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRK 284 + N R H Y V+++ SP + G DG++ W+L K Sbjct: 546 --WNLSNCKLRSTLAGH--------TGY-VSTVAVSPDGSLCASGGKDGVVLLWDLAEGK 594 Query: 285 KIKNFAKFNEDSVVKIAC---SDNILCLATSD 313 K+ + +SV+ C + LC AT Sbjct: 595 KLYSLE---ANSVIHALCFSPNRYWLCAATEH 623 >5GAN-H nrPDB Length = 465 Score = 54.4 bits (129), Expect = 7e-08, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 44/128 (34%), Gaps = 7/128 (5%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ISD+K PS + S D + ++ D LLQ K D + + Sbjct: 268 ISDVKYHPSGKFIGSASHDMTWRLW--DASTHQELLLQEGHDKGVFSLSFQCDGSL--VC 323 Query: 74 VGTVQGEILKVDL-IGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNY 132 G + + D+ GS +++ + ++ DG+I V D R Sbjct: 324 SGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAW--SPNGYQVATGGGDGIINVWDIRKR 381 Query: 133 GDGVIAVK 140 +G + Sbjct: 382 DEGQLNQI 389 Score = 36.3 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 17/97 (17%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTR-----------KKIKNFAKFNED---SVV 298 P+ ++ +SP + T G DGII+ W+++ R + I +F+++ + Sbjct: 351 PIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKL 410 Query: 299 KIACSDNILCLATSDDTFKTNAA---IDQTIELNASS 332 DN++ + +SD K + D+ I L+ S+ Sbjct: 411 VSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISN 447 >5M25-A nrPDB Length = 434 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 43/118 (36%), Gaps = 6/118 (5%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQ 71 +Y+ P +L++ S+D S+ ++ K + L + D + Sbjct: 230 NYVFCCNFNPQSNLIVSGSFDESVRIWDVK-TGKCLKTLPA-HSDPVSAVHFNRDGSL-- 285 Query: 72 IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRIC-KYGDDKLIAASWDGLIEVID 128 I + G D + L +++ N + + ++AA+ D +++ D Sbjct: 286 IVSSSYDGLCRIWDTASGQCLKTLIDDD-NPPVSFVKFSPNGKYILAATLDNTLKLWD 342 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 50/119 (42%), Gaps = 7/119 (5%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ISD+ +LL+ S D +L ++ K + L+ + CCNF ++L I Sbjct: 190 ISDVAWSSDSNLLVSASDDKTLKIWDVS-SGKCLKTLKG-HSNYVF-CCNFNPQSNL-IV 245 Query: 74 VGTVQGEILKVDLIGSPSFQAL-TNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 G+ + D+ + L +++ + ++++S+DGL + D + Sbjct: 246 SGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 302 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 45/116 (38%), Gaps = 4/116 (3%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 +S +K P+ +L + D +L ++ + + K + + + + NF I Sbjct: 317 VSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 375 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW--DGLIEVI 127 G+ + +L Q L + + I C ++ + +A+ D I++ Sbjct: 376 SGSEDNLVYIWNLQTKEIVQKLQGHTDVV-ISTACHPTENIIASAALENDKTIKLW 430 >2HES-X nrPDB Length = 330 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 62/302 (20%), Positives = 110/302 (36%), Gaps = 55/302 (18%) Query: 7 EQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAK---NVDLLQSL--RYKHPLLC 61 E A K I + P SLL S+D +++++ + A +DLL + Sbjct: 54 ETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGV 113 Query: 62 CNFIDNTDLQIYVGTV--QGEILKVDLIGS----PSFQALT-NNEANLGICRICKYGDDK 114 D Y+ T + + S L +++ + + Sbjct: 114 AWSNDG----YYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIW--HPSEAL 167 Query: 115 LIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQ- 173 L ++S+D + + ++Y D V LN + V + F RL G ++S V+ Sbjct: 168 LASSSYDDTVRIW--KDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRV 225 Query: 174 WFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQE--------GY----ACSSIDGRVAVE 221 W + EDD A+LP + G+ A DG +AV Sbjct: 226 WKYMGDDEDDQQEWV---------CEAILPDVHKRQVYNVAWGFNGLIASVGADGVLAV- 275 Query: 222 FFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHK--FLYTAGSDGIISCWN 279 + + G+ +KR CH Y +N +++ + L T G DGI++ W+ Sbjct: 276 YEEVDGEWKVFAKRAL--CH--------GVYEINVVKWLELNGKTILATGGDDGIVNFWS 325 Query: 280 LQ 281 L+ Sbjct: 326 LE 327 >2H9P-A nrPDB Length = 329 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 43/118 (36%), Gaps = 6/118 (5%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQ 71 +Y+ P +L++ S+D S+ ++ K + L + D + Sbjct: 125 NYVFCCNFNPQSNLIVSGSFDESVRIWDVK-TGKCLKTLPA-HSDPVSAVHFNRDGSL-- 180 Query: 72 IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRIC-KYGDDKLIAASWDGLIEVID 128 I + G D + L +++ N + + ++AA+ D +++ D Sbjct: 181 IVSSSYDGLCRIWDTASGQCLKTLIDDD-NPPVSFVKFSPNGKYILAATLDNTLKLWD 237 Score = 50.9 bits (120), Expect = 7e-07, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 50/119 (42%), Gaps = 7/119 (5%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ISD+ +LL+ S D +L ++ K + L+ + CCNF ++L I Sbjct: 85 ISDVAWSSDSNLLVSASDDKTLKIWDVS-SGKCLKTLKG-HSNYVF-CCNFNPQSNL-IV 140 Query: 74 VGTVQGEILKVDLIGSPSFQAL-TNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 G+ + D+ + L +++ + ++++S+DGL + D + Sbjct: 141 SGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 197 Score = 35.9 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 45/116 (38%), Gaps = 4/116 (3%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 +S +K P+ +L + D +L ++ + + K + + + + NF I Sbjct: 212 VSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 270 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW--DGLIEVI 127 G+ + +L Q L + + I C ++ + +A+ D I++ Sbjct: 271 SGSEDNLVYIWNLQTKEIVQKLQGHTDVV-ISTACHPTENIIASAALENDKTIKLW 325 >5NZU-C nrPDB Length = 905 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 44/227 (19%), Positives = 86/227 (37%), Gaps = 23/227 (10%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPL- 59 ++ V + +A DYI I + P++ +L +S D + ++ +D + + + + + Sbjct: 89 LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG-HTHYVMQ 147 Query: 60 LCCNFIDNTDLQIYVGTVQGEILKVDL-IGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + N DN Q ++ I L SP+F + + I LI+ Sbjct: 148 IVINPKDNN--QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISG 205 Query: 119 SWDGLIEVIDPRNYGDGVIAV-KNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRL 177 + D L+++ D +N N + ++ + T S V + +S +RL Sbjct: 206 ADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHS--STYRL 263 Query: 178 PLCEDDNGTIEESGLKY---QIRDVALLPKEQEGYACSSIDGRVAVE 221 ES L Y ++ VA L A +G + V+ Sbjct: 264 -----------ESTLNYGMERVWCVASLRGSNN-VALGYDEGSIIVK 298 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 23/48 (47%), Gaps = 2/48 (4%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA 301 V S++ P ++ + +G + WN +T+ +K F D V+ A Sbjct: 18 VKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFE--VCDLPVRAA 63 >6QX9-5O nrPDB Length = 357 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 45/305 (14%), Positives = 92/305 (30%), Gaps = 45/305 (14%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN 63 + + + + K P+ S L +D + ++ N L+ + Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMELHY 117 Query: 64 FIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGL 123 D + L + + + D + L + + + C + G + S DG Sbjct: 118 NTDGSML--FSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGT 175 Query: 124 IEVIDPRN-------YGDGVIAVKNLNSNNTKVK-----NKIFTMDTNSSRLIVGM---- 167 +++ D R + N + ++ N I D ++L M Sbjct: 176 VKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHA 235 Query: 168 -------NNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPK-----EQEGYACS-SI 214 +S+ + ++ + + R V + E+ CS S Sbjct: 236 DSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSP 295 Query: 215 DGRVAVEFFDDQGDDYNSSKRFAF----RCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAG 270 DG S+ RF + R+ K A +N + F P + +A Sbjct: 296 DG---------SKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISAS 346 Query: 271 SDGII 275 SD + Sbjct: 347 SDKRL 351 >5FL8-q nrPDB Length = 515 Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 52/301 (17%), Positives = 92/301 (30%), Gaps = 29/301 (9%) Query: 13 YISDIKIIPSKSL-LLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQ 71 I P S ++ + D + ++ D Q L Y L D Sbjct: 145 TILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTL--KGHYNWVLCVSWSPDGEV-- 200 Query: 72 IYVGTVQGEILKVDLIGSPSFQALT--NNEANLGICR----ICKYGDD-KLIAASWDGLI 124 I G++ I D +++ + + K G +L ++S DG I Sbjct: 201 IATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTI 260 Query: 125 EVIDPRNYGDGVIAVKNLNS------------NNTKVKNKIFTMDTNSSRLIVGMNNSQV 172 ++ D + + NS + + D NS + + S Sbjct: 261 KIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYSGSHDRTVRVWDINSQGRCINILKSHA 320 Query: 173 QWFRLPLCEDDN----GTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGD 228 W D G + +G K + A + +G + E D Sbjct: 321 HWVNHLSLSTDYALRIGAFDHTGKKPSTPEEAQKKALENYEKICKKNGN-SEEMMVTASD 379 Query: 229 DYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKN 288 DY + + + T VN + FSP +++ +A D I W+ + K I Sbjct: 380 DYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFIST 439 Query: 289 F 289 F Sbjct: 440 F 440 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 25/78 (32%), Gaps = 3/78 (3%) Query: 55 YKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDD 113 + +LC F +T ++ G D L + L + + Sbjct: 142 HGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSW--SPDGE 199 Query: 114 KLIAASWDGLIEVIDPRN 131 + S D I + DP++ Sbjct: 200 VIATGSMDNTIRLWDPKS 217 Score = 35.9 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 10/115 (8%), Positives = 33/115 (28%), Gaps = 7/115 (6%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ++ + P ++ S+D S+ ++ K + + D L Sbjct: 405 VNHVAFSPDGRYIVSASFDNSIKLWDGRD-GKFISTFRG-HVASVYQVAWSSDCRLL--V 460 Query: 74 VGTVQGEILKVDLIGSP-SFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVI 127 + + D+ S + + + ++ + D ++ + Sbjct: 461 SCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDW--SVDGKRVCSGGKDKMVRLW 513 Score = 27.8 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 10/119 (8%) Query: 16 DIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVG 75 K S+ +++ S D ++ ++ K + + K D I Sbjct: 364 CKKNGNSEEMMVTASDDYTMFLWNPLKSTKPIARMTG-HQKLVNHVAFSPDGRY--IVSA 420 Query: 76 TVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDK--LIAASWDGLIEVIDPRN 131 + I D + + + D L++ S D ++V D R Sbjct: 421 SFDNSIKLWDGRDGKFISTFRGHVASVYQVAW----SSDCRLLVSCSKDTTLKVWDVRT 475 >6CHG-A nrPDB Length = 312 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 84/231 (36%), Gaps = 26/231 (11%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 +++++ K+ I+ + P + S D ++ + I + L+ + Sbjct: 45 KMMKLTTTHKECINCLCWSPDSKCIASGSEDFTVEITHI-IYGRIRRLMG--HTAPVISI 101 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASW 120 C L ++ I + ++ + + ++ +++A + I I K+ L + S+ Sbjct: 102 CYNNKGNIL--CSSSMDESIKEWHVLSGTALKTMSAHSDAVVSID-IPKFDSSILSSGSY 158 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSR--LIVGMNNSQVQWFRLP 178 DGLI + D + + + I T+ + + L+V ++ V+ Sbjct: 159 DGLIRIFDTESGHCLKTLTYDKDWIAEDGVVPISTVKFSRNGKFLLVKSLDNVVK----- 213 Query: 179 LCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDD 229 L E GT+ + L A L Y C +E QG D Sbjct: 214 LWEYTRGTVVRTFLWPHQETKAKLK-----YNCG-------LELIYPQGKD 252 >5NNZ-B nrPDB Length = 415 Score = 49.4 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 42/120 (35%), Gaps = 9/120 (7%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 I + P +L+ S D + ++ +N + + +LR + + + +I Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDI----QNGEEVYTLRGHSAEIISLSFNTSGDRII 235 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDK--LIAASWDGLIEVIDPRN 131 G+ ++ D L + A + + D ++ S D ++ D N Sbjct: 236 TGSFDHTVVVWDADTGRKVNILIGHCAEIS---SASFNWDCSLILTGSMDKTCKLWDATN 292 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 51/329 (15%), Positives = 116/329 (35%), Gaps = 36/329 (10%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ++++ + S S + S+D + ++ + ++ L+ R + + F + +I Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWDTA-SGEELNTLEGHR--NVVYAIAFNNPYGDKIA 151 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYG 133 G+ + + + A + +C + S D ++ D +N Sbjct: 152 TGSFDKTCKLWSVETGKCYHTFRGHTAEI-VCLSFNPQSTLVATGSMDTTAKLWDIQNGE 210 Query: 134 DGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTI----EE 189 + V L ++ ++ + F +T+ R+I G + V + N I E Sbjct: 211 E----VYTLRGHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEI 264 Query: 190 SGLKYQIRDVALLP----------KEQEGYACSSIDG---RVAVEFFDDQG------DDY 230 S + +L G +++ G + FD G Sbjct: 265 SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASAD 324 Query: 231 NSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFA 290 +++ F+ + K ++ I F+P+ L T SD W+ QT + ++ Sbjct: 325 GTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE 384 Query: 291 KFNEDSVVKIACS--DNILCLATSDDTFK 317 + D + A + NI+ + D+T + Sbjct: 385 G-HTDEIFSCAFNYKGNIVITGSKDNTCR 412 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 21/71 (29%), Gaps = 4/71 (5%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 IS I P + LL S D + ++ + + +L+ C + Sbjct: 348 ISKISFNPQGNHLLTGSSDKTARIWDAQ-TGQCLQVLEG-HTDEIFSCAFNYKGNI--VI 403 Query: 74 VGTVQGEILKV 84 G+ Sbjct: 404 TGSKDNTCRIW 414 >3I2N-A nrPDB Length = 357 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 65/358 (18%), Positives = 135/358 (37%), Gaps = 51/358 (14%) Query: 3 IVQIEQAPKDYISDIKIIP-SKSLLLITSWDGSLTVYK-FDIQAKNVDLLQSLRYKHPLL 60 I I++ + D K +P S + + ++ V + ++IQ ++ LL+ + P+ Sbjct: 10 IAHIQKGFNYTVFDCKWVPCSAKFVTMGNFARGTGVIQLYEIQHGDLKLLREIEKAKPIK 69 Query: 61 CCNFIDNTDLQIYVGTVQ--GEILKVDLIGS--PSFQALTN----NEANLGICRICKYGD 112 C F + Q Y+ T G + +L P + + N + G Sbjct: 70 CGTFGATSLQQRYLATGDFGGNLHIWNLEAPEMPVYSVKGHKEIINAIDGIGGLGIGEGA 129 Query: 113 DKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIF---TMDTNSSRLIVGMNN 169 +++ S DG ++V DPR D V ++ + N + + + + G +N Sbjct: 130 PEIVTGSRDGTVKVWDPRQKDDPVANMEPVQGENKRDCWTVAFGNAYNQEERVVCAGYDN 189 Query: 170 SQVQWFRLPLCEDDNGTIEESG---LKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQ 226 ++ F L T ++G L++ +D+++ +S++G+ FD Sbjct: 190 GDIKLFDLRNMALRWETNIKNGVCSLEFDRKDISM-----NKLVATSLEGK--FHVFD-- 240 Query: 227 GDDYNSSKRFAF---RCHRLNLKDTNLAYPVNSIEFSPRHKFLY-TAGSDGIISCWNLQ- 281 + +K FA + H+ V + P+++ L+ TAG G + W + Sbjct: 241 MRTQHPTKGFASVSEKAHKST---------VWQVRHLPQNRELFLTAGGAGGLHLWKYEY 291 Query: 282 --TRKKIKNFAKFNEDSVVKIACSDNILCLA---TSDDTFKTN------AAIDQTIEL 328 R K K+ ++ N+ +S D ++ DQT+ + Sbjct: 292 PIQRSK-KDSEGIEMGVAGSVSLLQNVTLSTQPISSLDWSPDKRGLCVCSSFDQTVRV 348 >4V8M-A7 nrPDB Length = 318 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 22/157 (14%), Positives = 53/157 (33%), Gaps = 10/157 (6%) Query: 12 DYISDIKIIPSKS--LLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTD 69 D++S ++ PS +++ WD + V+ + V L+ + D + Sbjct: 153 DWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLA-TGRLVTDLKG-HTNYVTSVTVSPDGSL 210 Query: 70 LQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP 129 G DL + + IC + AA+ + I + D Sbjct: 211 CA--SSDKDGVARLWDLTKGEALSEMAAGAPINQICF--SPNRYWMCAAT-EKGIRIFDL 265 Query: 130 RNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVG 166 N D ++ + + + K+ + ++ ++ + Sbjct: 266 EN-KDIIVELAPEHQGSKKIVPECVSIAWSADGSTLY 301 Score = 48.2 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 42/118 (35%), Gaps = 6/118 (5%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++SD+ + + + + SWD SL ++ L K L DN QI Sbjct: 69 FVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLG--HTKDVLSVAFSPDN--RQI 124 Query: 73 YVGTVQGEILKVDLIGS--PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVID 128 G + ++ G + + + + +++ WD L++V D Sbjct: 125 VSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWD 182 >3JB9-g nrPDB Length = 558 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 45/273 (16%), Positives = 93/273 (34%), Gaps = 28/273 (10%) Query: 14 ISDIKIIP-SKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 IS ++ P S LLL S D + +++ +++ + D Sbjct: 269 ISCLRFFPISGHLLLSGSMDNQIKIWEV-YHDRSLLRTFQGHARPIRDLSFSQDGRSF-- 325 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGD-DKLIAASWDGLIEVIDPRN 131 + I D ++ + ++ +A + D I D R+ Sbjct: 326 LSTSFDKTIKLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRS 385 Query: 132 YGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQ--WFRLPLCEDDNGTIEE 189 +L N+ T N R + ++S ++ + P+ I Sbjct: 386 PDIVQAYDHHLGGINS------ITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIA- 438 Query: 190 SGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTN 249 + + VAL P + AC S+D + + + Y +K+ F+ + + Sbjct: 439 ---MHSMPRVALRPNGKS-IACQSLDNCI---YVYSAYEKYRQNKKKVFKGYSCSG---- 487 Query: 250 LAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQT 282 Y + + FSP +F+++ S G W+ +T Sbjct: 488 --YSLE-VGFSPDGRFVFSGDSSGNACFWDWKT 517 >5OPT-p nrPDB Length = 318 Score = 47.8 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 21/133 (15%), Positives = 43/133 (32%), Gaps = 10/133 (7%) Query: 12 DYISDIKIIPS--KSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTD 69 D++S ++ PS L++ WD + V+ + + L+ + D + Sbjct: 153 DWVSCVRFSPSLETPLIVSGGWDNLVKVWDIA-SGRLLTDLKG-HTNYITSVTVSPDGSL 210 Query: 70 LQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP 129 G DL + + IC + AA+ + I + D Sbjct: 211 CA--SSDKDGVARLWDLTKGEALSEMAAGAPINQICF--SPNRYWMCAAT-EKGIRIFDL 265 Query: 130 RNYGDGVIAVKNL 142 N D ++ + Sbjct: 266 EN-KDVIVELAPE 277 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 41/118 (34%), Gaps = 6/118 (5%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++SD+ + + + SWD SL ++ L K L DN QI Sbjct: 69 FVSDVALSNNGDFAVSASWDHSLRLWNLQTGVCQHKFLG--HTKDVLSVTFSPDN--RQI 124 Query: 73 YVGTVQGEILKVDLIGS--PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVID 128 G + ++ G + + + + +++ WD L++V D Sbjct: 125 VSGGRDNALRVWNVKGECLHTLGRGAHTDWVSCVRFSPSLETPLIVSGGWDNLVKVWD 182 >6EOJ-D nrPDB Length = 470 Score = 47.4 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 38/289 (13%), Positives = 90/289 (31%), Gaps = 57/289 (19%) Query: 8 QAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDN 67 QA ++ +K ++ DG + +++ + V + + + + Sbjct: 132 QAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFS--MVKEIDAAHTESIRDMAFS--S 187 Query: 68 TDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEV 126 D + + + + + L+ ++ + +AS D L+++ Sbjct: 188 NDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDW--HPEMGLIASASKDNLVKL 245 Query: 127 IDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGT 186 DPR+ N ++ +K K + T Q L + + + Sbjct: 246 WDPRSG----------NCISSILKFKHTVLKT----------RFQPTKGNLLMAISKDKS 285 Query: 187 IEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLK 246 ++Y ++++ + E + + + N S F C+ +LK Sbjct: 286 CRVFDIRYSMKELMCVRDETD--------------YMTLEWHPINESM-FTLACYDGSLK 330 Query: 247 DTNL-----------AYP----VNSIEFSPRHKFLYTAGSDGIISCWNL 280 +L Y + S+ ++P TA D I W Sbjct: 331 HFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTR 379 >3MKQ-A nrPDB Length = 814 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 7/130 (5%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 ++V E P DYI I + P+K +L S D ++ ++ ++ N L Q+ + Sbjct: 89 KVVDFEAHP-DYIRSIAVHPTKPYVLSGSDDLTVKLWNWE---NNWALEQTFEGHEHFVM 144 Query: 62 CNFIDNTDLQIYVGTV-QGEILKVDL-IGSPSFQALTNNE-ANLGICRICKYGDDKLIAA 118 C + D + + L +P+F T E + +I A Sbjct: 145 CVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITA 204 Query: 119 SWDGLIEVID 128 S D I++ D Sbjct: 205 SDDLTIKIWD 214 Score = 35.5 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 39/127 (30%), Gaps = 11/127 (8%) Query: 11 KDYISDIKIIPSK-SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTD 69 + ++ + P S D ++ V+ N L N++D Sbjct: 140 EHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERG-----VNYVDYYP 194 Query: 70 LQ----IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE 125 L + + I D L + +N+ + +I+ S DG ++ Sbjct: 195 LPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFA-VFHPTLPIIISGSEDGTLK 253 Query: 126 VIDPRNY 132 + + Y Sbjct: 254 IWNSSTY 260 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 V I+F P ++ T G + WN +T+ ++++ ++ V+ Sbjct: 16 VKGIDFHPTEPWVLTTLYSGRVEIWNYETQVEVRSIQ--VTETPVRA 60 >6QDV-o nrPDB Length = 513 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 52/286 (18%), Positives = 103/286 (36%), Gaps = 30/286 (10%) Query: 4 VQIEQAPKDYISDIKIIP-SKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCC 62 + + +S +++ P S LLL S D + +++ + + + K C Sbjct: 215 IHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIG-HSKAVRDIC 273 Query: 63 NFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDK---LIAAS 119 T Q + D TN + + C +DK +A Sbjct: 274 FNTAGT--QFLSAAYDRYLKLWDTETGQCISRFTNRK--VPYCVKFNPDEDKQNLFVAGM 329 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNS-QVQWFRLP 178 D I D R+ G I + N I +D N + + S +V + +P Sbjct: 330 SDKKIVQWDIRS---GEIVQEYDRHLGA--VNTIVFVDENRRFVSTSDDKSLRVWEWDIP 384 Query: 179 LCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAF 238 + + + + V L P + AC S+D ++ + F Q + + +K+ F Sbjct: 385 V----DFKYIAEPSMHSMPAVTLSPNGK-WLACQSMDNQILI--FGAQ-NRFRLNKKKIF 436 Query: 239 RCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRK 284 + H + Y ++FSP ++ + +G ++ W+ +T K Sbjct: 437 KGHMVAG------YACQ-VDFSPDMSYVISGDGNGKLNIWDWKTTK 475 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 59/172 (34%), Gaps = 46/172 (26%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQ-SLRYKHPL- 59 +IVQ ++ I + + TS D SL V+++DI + + S+ + Sbjct: 343 EIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT 402 Query: 60 -------LCCNFIDNTDL-------------QIYVG-TVQGEILKVDLIGSPSFQAL--- 95 L C +DN L +I+ G V G +VD S+ Sbjct: 403 LSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDG 462 Query: 96 -------------------TNNEANLGICRICKYGDDKLIAASWDGLIEVID 128 +++ +G + K+I WDGLI++ D Sbjct: 463 NGKLNIWDWKTTKLYSRFKAHDKVCIGAVW-HPHETSKVITCGWDGLIKLWD 513 >5YZG-W nrPDB Length = 579 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 52/286 (18%), Positives = 103/286 (36%), Gaps = 30/286 (10%) Query: 4 VQIEQAPKDYISDIKIIP-SKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCC 62 + + +S +++ P S LLL S D + +++ + + + K C Sbjct: 281 IHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIG-HSKAVRDIC 339 Query: 63 NFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDK---LIAAS 119 T Q + D TN + + C +DK +A Sbjct: 340 FNTAGT--QFLSAAYDRYLKLWDTETGQCISRFTNRK--VPYCVKFNPDEDKQNLFVAGM 395 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNS-QVQWFRLP 178 D I D R+ G I + N I +D N + + S +V + +P Sbjct: 396 SDKKIVQWDIRS---GEIVQEYDRHLGA--VNTIVFVDENRRFVSTSDDKSLRVWEWDIP 450 Query: 179 LCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAF 238 + + + + V L P + AC S+D ++ + F Q + + +K+ F Sbjct: 451 V----DFKYIAEPSMHSMPAVTLSPNGK-WLACQSMDNQILI--FGAQ-NRFRLNKKKIF 502 Query: 239 RCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRK 284 + H + Y ++FSP ++ + +G ++ W+ +T K Sbjct: 503 KGHMVAG------YACQ-VDFSPDMSYVISGDGNGKLNIWDWKTTK 541 Score = 33.6 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 59/172 (34%), Gaps = 46/172 (26%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQ-SLRYKHPL- 59 +IVQ ++ I + + TS D SL V+++DI + + S+ + Sbjct: 409 EIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT 468 Query: 60 -------LCCNFIDNTDL-------------QIYVG-TVQGEILKVDLIGSPSFQAL--- 95 L C +DN L +I+ G V G +VD S+ Sbjct: 469 LSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDG 528 Query: 96 -------------------TNNEANLGICRICKYGDDKLIAASWDGLIEVID 128 +++ +G + K+I WDGLI++ D Sbjct: 529 NGKLNIWDWKTTKLYSRFKAHDKVCIGAVW-HPHETSKVITCGWDGLIKLWD 579 >2YNP-A nrPDB Length = 604 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 7/130 (5%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 ++V E P DYI I + P+K +L S D ++ ++ ++ N L Q+ + Sbjct: 89 KVVDFEAHP-DYIRSIAVHPTKPYVLSGSDDLTVKLWNWE---NNWALEQTFEGHEHFVM 144 Query: 62 CNFIDNTDLQIYVGTV-QGEILKVDL-IGSPSFQALTNNE-ANLGICRICKYGDDKLIAA 118 C + D + + L +P+F T E + +I A Sbjct: 145 CVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITA 204 Query: 119 SWDGLIEVID 128 S D I++ D Sbjct: 205 SDDLTIKIWD 214 Score = 35.1 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 18/125 (14%), Positives = 38/125 (30%), Gaps = 11/125 (8%) Query: 13 YISDIKIIPSK-SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQ 71 ++ + P S D ++ V+ N L N++D L Sbjct: 142 FVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERG-----VNYVDYYPLP 196 Query: 72 ----IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVI 127 + + I D L + +N+ + +I+ S DG +++ Sbjct: 197 DKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFA-VFHPTLPIIISGSEDGTLKIW 255 Query: 128 DPRNY 132 + Y Sbjct: 256 NSSTY 260 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 V I+F P ++ T G + WN +T+ ++++ ++ V+ Sbjct: 16 VKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQ--VTETPVRA 60 >6N9G-C nrPDB Length = 353 Score = 44.7 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 7/131 (5%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLR-YKHPLLCCNFIDNTDL 70 +Y+S S +L S DG+ ++ + + LLQS + +LC + + Sbjct: 154 NYLSACSFTNSDMQILTASGDGTCALWDVE-SGQ---LLQSFHGHGADVLCLDLAPSETG 209 Query: 71 QIYV-GTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP 129 +V G + + D+ QA +E+++ R D + S D + D Sbjct: 210 NTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRY-YPSGDAFASGSDDATCRLYDL 268 Query: 130 RNYGDGVIAVK 140 R + I K Sbjct: 269 RADREVAIYSK 279 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 44/127 (34%), Gaps = 7/127 (5%) Query: 10 PKDYISDIKIIPSKSLLLITSWDGSLTVYKFD-IQAKNV---DLLQSLRYKHPLLCCNFI 65 P ++ PS + D +VY + +N+ ++ + L C+F Sbjct: 104 PCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNY-LSACSFT 162 Query: 66 DNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLI 124 N+D+QI + G D+ Q+ + L + + ++ D Sbjct: 163 -NSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKA 221 Query: 125 EVIDPRN 131 V D R+ Sbjct: 222 MVWDMRS 228 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 20/129 (15%), Positives = 45/129 (34%), Gaps = 9/129 (6%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFD-IQAKNVDLLQSLRYKHPLL 60 Q VQ + + ++ ++ PS S D + +Y + + +S+ + Sbjct: 230 QCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG---- 285 Query: 61 CCNFIDNT--DLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + +D + ++ G I D++ L +E + R+ + Sbjct: 286 -ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRV-SPDGTAFCSG 343 Query: 119 SWDGLIEVI 127 SWD + V Sbjct: 344 SWDHTLRVW 352 >5MZH-A nrPDB Length = 452 Score = 44.7 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 42/118 (35%), Gaps = 5/118 (4%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 I + P +++ S D + ++ + + L ++ ++ F DL I Sbjct: 182 IVCLSFNPQSTIIATGSMDNTAKLWDVETGQERATLAG---HRAEIVSLGFNTGGDL-IV 237 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 G+ + D+ L+ + + + Y +++ S D + D R+ Sbjct: 238 TGSFDHDSRLWDVRTGQCVHVLSGHRGEVSSTQF-NYAGTLVVSGSIDCTSRLWDVRS 294 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 26/72 (36%), Gaps = 3/72 (4%) Query: 58 PLLCCNFIDNTDLQIYVGTVQGEILKVD-LIGSPSFQALTNNEANLGICRICKYGDDKLI 116 PL C F + D + G+ + G F + I YG DK++ Sbjct: 96 PLTNCAFNKSGD-RFITGSYDRTCKVWNTFTGEEVFTLEGHKNVVYAIAFNNPYG-DKIV 153 Query: 117 AASWDGLIEVID 128 S+D ++ D Sbjct: 154 TGSFDKTCKLWD 165 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 18/128 (14%), Positives = 40/128 (31%), Gaps = 7/128 (5%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 Q V + + +S + + +L++ S D + ++ + + + Q L Sbjct: 254 QCVHVLSGHRGEVSSTQFNYAGTLVVSGSIDCTSRLWDVR-SGRCLSVKQG-HTDEVLDV 311 Query: 62 CNFIDNTDLQIYVGTVQGEILKV-DLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 D ++ + G L G + + + +LI AS Sbjct: 312 AF--DAAGTKMVSASADGSARLYHTLTGVCQHTLVGHEGEISKVAF--NPQGTRLITASS 367 Query: 121 DGLIEVID 128 D + D Sbjct: 368 DKTCRLWD 375 >5WYK-BB nrPDB Length = 943 Score = 44.7 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Query: 23 KSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEIL 82 LL + DG + V+ D+ +K V L + L D T ++ G+ I+ Sbjct: 91 TDLLAVGYADGVIKVW--DLMSKTVLLNFNGHKAAITLL--QFDGTGTRLISGSKDSNII 146 Query: 83 KVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNY 132 DL+G L +++ ++ G+D LI+ S DG+I++ D + + Sbjct: 147 VWDLVGEVGLYKLRSHKDSITGFWCQ--GEDWLISTSKDGMIKLWDLKTH 194 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 55/320 (17%), Positives = 107/320 (33%), Gaps = 51/320 (15%) Query: 11 KDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDL 70 K I+ ++ + + L+ S D ++ V+ + + L+S + C D Sbjct: 121 KAAITLLQFDGTGTRLISGSKDSNIIVWDL-VGEVGLYKLRSHKDSITGFWCQGED---- 175 Query: 71 QIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 + + G I DL + + A+ G C DD LI D +++ Sbjct: 176 WLISTSKDGMIKLWDLKTHQCIET---HIAHTGECWGLAVKDDLLITTGTDSQVKIWKLD 232 Query: 131 NYGDGVIAVKNL------NSNNTKVKNKIFTMDTNSSRLIVGMNNSQ-VQWFRLPLCED- 182 D + S +K + T ++ + N + ++ FR+ E+ Sbjct: 233 IENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKTIETFRIRKEEEI 292 Query: 183 ------------DNGTIEESGLK--------------------YQIRDVALLPKEQEGYA 210 + G EE K Y+I+ + Sbjct: 293 ARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSKLE 352 Query: 211 CSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAG 270 +E++ + + + + H + L+ V SI+ S +K L TA Sbjct: 353 LVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRT--DVRSIDISDDNKLLATA- 409 Query: 271 SDGIISCWNLQTRKKIKNFA 290 S+G + WN++T K I+ F Sbjct: 410 SNGSLKIWNIKTHKCIRTFE 429 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 10/120 (8%) Query: 24 SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEILK 83 + LL T+ +GSL ++ K +++ + L C F+ L + +GT GE+ Sbjct: 403 NKLLATASNGSLKIWNI----KTHKCIRTFECGYAL-TCKFLPGGLL-VILGTRNGELQL 456 Query: 84 VDLIGSPSFQALT--NNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKN 141 DL S + ++ A + +L+ S D ++ D + V KN Sbjct: 457 FDLASSSLLDTIEDAHDAAIWSLDLTS--DGKRLVTGSADKTVKFWDFKVENSLVPGTKN 514 >5WLC-LJ nrPDB Length = 513 Score = 44.7 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 40/233 (17%), Positives = 70/233 (30%), Gaps = 27/233 (11%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 Q+++ KD + LL G ++VY + + L + HP Sbjct: 72 QVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYD-SYNPRTILLSINAST-HPTHV 129 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDLIGS--PSFQALTNNEANLGICRICKYGDDKLIAAS 119 F + + + D+ + P + + + I + S Sbjct: 130 TKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPH-LVATGS 188 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVK--NKIFTMDTNSSRLIVGMNNSQVQ---- 173 +DGLI + D R+ G I N + V + + + V S + Sbjct: 189 YDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSPTQIVSCGGNNFKVWDLTSNKKLYER 248 Query: 174 -WFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDD 225 F + D +S + Q SS+DG V V FD Sbjct: 249 GNFNKAVTCLDYVENFDSPM-------------QSALIASSLDGHVKV--FDP 286 Score = 33.9 bits (76), Expect = 0.095, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 12/88 (13%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA--------CSD 304 V I F+P+H + S + ++ +TR+ IK F++F +D V + C+ Sbjct: 41 SVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRF-KDVVYSASFRSDGKLLCAG 99 Query: 305 NILCLATSDDTFKTNAAIDQTIELNASS 332 + L + D++ + + +NAS+ Sbjct: 100 DATGLVSVYDSYNPRTIL---LSINAST 124 >3JB9-L nrPDB Length = 340 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 20/149 (13%), Positives = 44/149 (29%), Gaps = 12/149 (8%) Query: 18 KIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTV 77 + PS S D + ++ KN +L + D+ +Y + Sbjct: 57 RFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCK-GAITDLQWSRDSRV--VYCSSS 113 Query: 78 QGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVI 137 ++ D + + + + + K G + L + S D ++V D R+ Sbjct: 114 DTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKT 173 Query: 138 AVKNLNSNNTKVKNKIFTMDTNSSRLIVG 166 + K + + V Sbjct: 174 IEE---------KYPLTAVAIAQQGTQVF 193 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 6/108 (5%) Query: 23 KSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEIL 82 LL S D ++ V+ +++ D ++++ K+PL I Q+++G + G I Sbjct: 148 SELLTSVSDDCTMKVWD----SRSKDCIKTIEEKYPLTAV-AIAQQGTQVFIGGIDGAIK 202 Query: 83 KVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 DL + L ++ + I K G L++ S D + + D + Sbjct: 203 IWDLRNNHCSHVLKGHKDIITSLAISKDG-SSLLSNSMDNTVRIFDVK 249 >4BTS-AR nrPDB Length = 343 Score = 44.0 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 44/131 (33%), Gaps = 21/131 (16%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++SD+ + + +SWD +L ++ D++ DN QI Sbjct: 78 FVSDLALSQENCFAISSSWDKTLRLW--DLRTGTTYKRFVGHQSEVYSVAFSPDN--RQI 133 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAAS------------- 119 + EI +++G F + + + ++ ++ Sbjct: 134 LSAGAEREIKLWNILGECKFSSAEKENHSD---WVSCVRYSPIMKSANKVQPFAPYFASV 190 Query: 120 -WDGLIEVIDP 129 WDG ++V + Sbjct: 191 GWDGRLKVWNT 201 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 54/170 (31%), Gaps = 24/170 (14%) Query: 116 IAASWDGLIEVIDPR---NYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMN--NS 170 I++SWD + + D R Y V + S N+ + + Sbjct: 92 ISSSWDKTLRLWDLRTGTTYKRFVGHQSEVYSVAFSPDNRQILSAGAEREIKLWNILGEC 151 Query: 171 QVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDY 230 + D + S + V +A DGR+ V + Sbjct: 152 KFSSAEKENHSDWVSCVRYSPIMKSANKVQPFAPY---FASVGWDGRLKV-------WNT 201 Query: 231 NSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNL 280 N R+ F+ H N VN + SP K++ T G D + W++ Sbjct: 202 NFQIRYTFKAHESN---------VNHLSISPNGKYIATGGKDKKLLIWDI 242 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 26/87 (29%), Gaps = 15/87 (17%) Query: 12 DYISDIKIIPSKS----------LLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 D++S ++ P WDG L V+ + Q + H Sbjct: 163 DWVSCVRYSPIMKSANKVQPFAPYFASVGWDGRLKVWNTNFQIRYTFKAHESNVNHL--- 219 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDLIG 88 I I G ++L D++ Sbjct: 220 --SISPNGKYIATGGKDKKLLIWDILN 244 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 23/46 (50%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVK 299 V S+ FSP ++ + +AG++ I WN+ K + K N V Sbjct: 121 VYSVAFSPDNRQILSAGAEREIKLWNILGECKFSSAEKENHSDWVS 166 >4V7E-Bg nrPDB Length = 380 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 56/313 (17%), Positives = 99/313 (31%), Gaps = 27/313 (8%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGT 76 + P K+ ++ S DG L V+ K L + C + + G Sbjct: 72 LDWTPEKNWIVSASQDGRLIVWNALTSQKT--HAIKLHCPWVMECAFAPNGQS--VACGG 127 Query: 77 VQGEILKVDLIGS-------PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP 129 + +L P + LT ++ C+ + +LI S D + D Sbjct: 128 LDSACSIFNLSSQADRDGNMPVSRVLTGHKGYASSCQYVPDQETRLITGSGDQTCVLWDV 187 Query: 130 RNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEE 189 I S +T + N++ I G ++ V+ + L + T Sbjct: 188 TTGQRISIFGSEFPSGHTADVLSLSINSLNANMFISGSCDTTVRLWDLRITSRAVRTY-- 245 Query: 190 SGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTN 249 G + I V P Q + S DG + D + + + D Sbjct: 246 HGHEGDINSVKFFPDGQR-FGTGSDDGTCRL-------FDMRTGHQLQVYNREPDRNDNE 297 Query: 250 LAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC-----SD 304 L V S+ FS + L+ S+G W+ + + N +I+C Sbjct: 298 LPI-VTSVAFSISGRLLFAGYSNGDCYVWDTLLAEMVLNLGTLQNSHEGRISCLGLSSDG 356 Query: 305 NILCLATSDDTFK 317 + LC + D K Sbjct: 357 SALCTGSWDKNLK 369 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 20/42 (47%) Query: 6 IEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNV 47 ++ + + IS + + S L SWD +L ++ F K V Sbjct: 339 LQNSHEGRISCLGLSSDGSALCTGSWDKNLKIWAFSGHRKIV 380 >5XYI-g nrPDB Length = 335 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 43/286 (15%), Positives = 88/286 (30%), Gaps = 49/286 (17%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++SD+ + S LL +SWD +L ++ D+ + L K L N +I Sbjct: 82 FVSDVSLSRDASHLLTSSWDSTLRLW--DLSTRTTKKLFLGHKKDVLGVTFSPCN--RRI 137 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRI----CKYGDDK-----LIAASWDGL 123 ++ +++G N + C D+ + WDG Sbjct: 138 ISVGRDNQVKIWNILG-------ENKAELQCSSWVTSVACAPMADETSPLVIAVGCWDGK 190 Query: 124 IEVIDPRNYGDGVIAVKNLNSNNTKVKN----KIFTMDTNSSRLIVGMNNSQVQWFRLPL 179 + + + K + T V K + ++++ + + + Sbjct: 191 VYIWSIEKEAKLIKEFKAHDGRCTSVDFTPDGKWVITGGSDRKVVMWLTENGAKTISFTA 250 Query: 180 CEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFR 239 + + + I A EG A I + ++ F Sbjct: 251 PSPVHA-VAACPTQAWI-CAATY----EGIAVWDIGAKQQIDLVQP---------NFKHE 295 Query: 240 CHRLNLKD---TNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQT 282 R + T LA+ + LY+ +DG I W +++ Sbjct: 296 GKRNAGRTPDCTCLAWAADG-------SVLYSGYNDGSIRAWEVKS 334 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 48/274 (17%), Positives = 91/274 (33%), Gaps = 37/274 (13%) Query: 65 IDNTDLQIYVGTVQGEILKVDLI------GSPSFQALTNNEANLGICRICKYGDDKLIAA 118 IDN + + L L +P + + +N + L+ + Sbjct: 41 IDNEHNYLVSASRDKSALVWKLNRTQEQWATPFTRLIGHNHFVSDVS--LSRDASHLLTS 98 Query: 119 SWDGLIEVID--PRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFR 176 SWD + + D R + K V T + R+I ++QV+ + Sbjct: 99 SWDSTLRLWDLSTRTTKKLFLGHKK------DVLG--VTFSPCNRRIISVGRDNQVKIWN 150 Query: 177 LPLCEDDNGTIEESGLKYQIRDVALLPKEQEGY--ACSSIDGRVAVEFFDDQGDDYNSSK 234 + ++ ++ S + A + E A DG+V + + + K Sbjct: 151 --ILGENKAELQCSSWVTSVAC-APMADETSPLVIAVGCWDGKVYIWSIEKEAKLIKEFK 207 Query: 235 RFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNE 294 RC S++F+P K++ T GSD + W + K +F + Sbjct: 208 AHDGRC--------------TSVDFTPDGKWVITGGSDRKVVMWLTENGAKTISFTAPSP 253 Query: 295 DSVVKIACSDNILCLATSDDTFKTNAAIDQTIEL 328 V + +C AT + + Q I+L Sbjct: 254 VHAVAACPTQAWICAATYEGIAVWDIGAKQQIDL 287 >1VYH-C nrPDB Length = 410 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 41/324 (12%), Positives = 103/324 (31%), Gaps = 47/324 (14%) Query: 19 IIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQ 78 P S+++ S D ++ V+ ++ + + D++ + + Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETG--DFERTLKGHTDSVQDI--SFDHSGKLLASCSAD 171 Query: 79 GEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIA 138 I D G + + ++ N+ I D +++AS D I++ + + Sbjct: 172 MTIKLWDFQGFECIRTMHGHDHNVSSVSI-MPNGDHIVSASRDKTIKMWEVQT------- 223 Query: 139 VKNLNSNNTKV----KNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKY 194 K + + + N ++ ++ Q R+ + E ++ Sbjct: 224 -----GYCVKTFTGHREWVRMVRPNQDGTLIASCSND-QTVRVWVVATKECKAELREHRH 277 Query: 195 QIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLN-----LKDTN 249 + ++ P E + S G + + S+ + ++ + Sbjct: 278 VVECISWAP-ESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 336 Query: 250 LAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCL 309 V + F KF+ + D + W+ + ++ +K Sbjct: 337 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEH--------------F 382 Query: 310 ATSDDTFKT-----NAAIDQTIEL 328 TS D KT ++DQT+++ Sbjct: 383 VTSLDFHKTAPYVVTGSVDQTVKV 406 Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 37/96 (38%), Gaps = 12/96 (12%) Query: 224 DDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTR 283 D + +++A HR PV + F P + +A D I W+ +T Sbjct: 90 DPKEWIPRPPEKYALSGHRS---------PVTRVIFHPVFSVMVSASEDATIKVWDYET- 139 Query: 284 KKIKNFAKFNEDSV--VKIACSDNILCLATSDDTFK 317 + K + DSV + S +L ++D T K Sbjct: 140 GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 46/120 (38%), Gaps = 13/120 (10%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLR-YKHPLLCCNFIDNTDL 70 D + DI S LL S D ++ ++ F + + ++++ + H + + + N D Sbjct: 151 DSVQDISFDHSGKLLASCSADMTIKLWDF----QGFECIRTMHGHDHNVSSVSIMPNGD- 205 Query: 71 QIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASW--DGLIEVI 127 I + I ++ + T + E R+ + D + AS D + V Sbjct: 206 HIVSASRDKTIKMWEVQTGYCVKTFTGHREWV----RMVRPNQDGTLIASCSNDQTVRVW 261 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 16/163 (9%), Positives = 46/163 (28%), Gaps = 27/163 (16%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 + ++ +S + I+P+ ++ S D ++ +++ V + + + Sbjct: 183 ECIRTMHGHDHNVSSVSIMPNGDHIVSASRDKTIKMWEVQ-TGYCV-KTFTGHREWVRMV 240 Query: 62 CNFIDNTDLQIYVGTV--QGEILKVDLIGSP-SFQALTNNEANLGICRICKYGDDK---- 114 D T + + + + + + I + Sbjct: 241 RPNQDGT----LIASCSNDQTVRVWVVATKECKAELREHRHVVECISWAPESSYSSISEA 296 Query: 115 --------------LIAASWDGLIEVIDPRNYGDGVIAVKNLN 143 L++ S D I++ D + V + N Sbjct: 297 TGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDN 339 >6ELZ-p nrPDB Length = 460 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 57/374 (15%), Positives = 126/374 (33%), Gaps = 75/374 (20%) Query: 9 APKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC------- 61 + +D++S + + ++ S+DG + + D+ NV S Sbjct: 101 SNEDWVSSLDVGDGSKHIISGSYDGIVRTW--DLSG-NVQKQYSGHSGPIRAVKYISNTR 157 Query: 62 -----------CNFIDNTDLQIYVGTVQGEILK--VDLIGSPSFQALT-NNEANLGICRI 107 N DL++ E V++ + L + + I Sbjct: 158 LVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSI--- 214 Query: 108 CKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLI--- 164 + ++++AS+D I Y + + + NN NKI T +L Sbjct: 215 DVSDNSRILSASYDNSIGFWST-IYKEMTVVDPLEDINNPN--NKISTAARKRRKLTMKD 271 Query: 165 --------VGMNNSQVQWFRLPLCEDDNGTIEES-GLKYQI--------RDV-------A 200 + + S + + + T+ S + I R + + Sbjct: 272 GTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYS 331 Query: 201 LLPKEQ----EGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNS 256 LL Q AC S + + D + + + H+ V+S Sbjct: 332 LLSIAQLSTLNLLACGSSARHITLH--DPRVGASSKVTQQQLIGHKN---------FVSS 380 Query: 257 IEFSPRHKFLYTAGS-DGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDT 315 ++ P ++++ +GS DG + W++++ + + ED V+ +D + + ++ Sbjct: 381 LDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITR--EDKSVQKGVNDKVFAVKWAEKV 438 Query: 316 FKTNAAIDQTIELN 329 +A D+ I++N Sbjct: 439 GIISAGQDKKIQIN 452 >5OQL-L nrPDB Length = 557 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 39/133 (29%), Gaps = 4/133 (3%) Query: 11 KDYISDIKIIPSKSLLLITSWDGSLTVYKF-DIQAKNVDLLQSLRYKHPLLCCNFIDNTD 69 +I P +L+ G + V+ + + + + Sbjct: 99 DSEAHCGEIRPDGRVLVAGEDTGRMQVFDVGQGTRAVILKTWHIHKQPVWVTKWS-PTEL 157 Query: 70 LQIYVGTVQGEILKVDLIGSPSFQALT--NNEANLGICRICKYGDDKLIAASWDGLIEVI 127 + + + DL + + T + G + L++ S+D + V Sbjct: 158 TTLMSCSDDKTVRLWDLPSNDPTRLFTGHTDYVRCGAFMPGSANSNLLVSGSYDETVRVW 217 Query: 128 DPRNYGDGVIAVK 140 D R G V+ K Sbjct: 218 DARAPGGAVMTFK 230 >6MZM-G nrPDB Length = 800 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 16/116 (13%), Positives = 39/116 (33%), Gaps = 7/116 (6%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ++ + P+ + + S D ++ ++ D+ N + + + L Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLW--DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA-- 685 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIA-ASWDGLIEVID 128 G G +L D+ +C + D +++A S D + + D Sbjct: 686 TGATDGRVLLWDI--GHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 18/151 (11%), Positives = 43/151 (28%), Gaps = 43/151 (28%) Query: 18 KIIPSKSLLLITSWDGSLTVYKFDI-------QAKNVDLLQSL----------------- 53 P ++ LL +S DG++ ++ + N + + Sbjct: 550 SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVA 609 Query: 54 ------RYKHP---------LLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-N 97 Y+ + C F N++ + G+ + D++ + T + Sbjct: 610 RLWATDHYQPLRIFAGHLADVNCTRFHPNSNY-VATGSADRTVRLWDVLNGNCVRIFTGH 668 Query: 98 NEANLGICRICKYGDDKLIAASWDGLIEVID 128 + L + DG + + D Sbjct: 669 KGPIHSLTF--SPNGRFLATGATDGRVLLWD 697 Score = 34.3 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNL 280 P++S+ FSP +FL T +DG + W++ Sbjct: 671 PIHSLTFSPNGRFLATGATDGRVLLWDI 698 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 43/119 (36%), Gaps = 9/119 (7%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN 63 V+I K I + P+ L + DG + ++ V L+ H C+ Sbjct: 662 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG-HGLMVGELK----GHTDTVCS 716 Query: 64 FIDNTDLQIY-VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKY-GDDKLIAASW 120 + D +I G++ + D I +F+ L ++ I +L+ ++ Sbjct: 717 LRFSRDGEILASGSMDNTVRLWDAI--KAFEDLETDDFTTATGHINLPENSQELLLGTY 773 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRK 284 PV FSP +L ++ DG + W+LQT Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576 >6F3T-A nrPDB Length = 608 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 16/116 (13%), Positives = 39/116 (33%), Gaps = 7/116 (6%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ++ + P+ + + S D ++ ++ D+ N + + + L Sbjct: 438 VNCTRFHPNSNYVATGSADRTVRLW--DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA-- 493 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIA-ASWDGLIEVID 128 G G +L D+ +C + D +++A S D + + D Sbjct: 494 TGATDGRVLLWDI--GHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 547 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 18/151 (11%), Positives = 43/151 (28%), Gaps = 43/151 (28%) Query: 18 KIIPSKSLLLITSWDGSLTVYKFDI-------QAKNVDLLQSL----------------- 53 P ++ LL +S DG++ ++ + N + + Sbjct: 358 SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVA 417 Query: 54 ------RYKHP---------LLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-N 97 Y+ + C F N++ + G+ + D++ + T + Sbjct: 418 RLWATDHYQPLRIFAGHLADVNCTRFHPNSNY-VATGSADRTVRLWDVLNGNCVRIFTGH 476 Query: 98 NEANLGICRICKYGDDKLIAASWDGLIEVID 128 + L + DG + + D Sbjct: 477 KGPIHSLTF--SPNGRFLATGATDGRVLLWD 505 Score = 34.3 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNL 280 P++S+ FSP +FL T +DG + W++ Sbjct: 479 PIHSLTFSPNGRFLATGATDGRVLLWDI 506 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 43/119 (36%), Gaps = 9/119 (7%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN 63 V+I K I + P+ L + DG + ++ V L+ H C+ Sbjct: 470 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG-HGLMVGELK----GHTDTVCS 524 Query: 64 FIDNTDLQIY-VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKY-GDDKLIAASW 120 + D +I G++ + D I +F+ L ++ I +L+ ++ Sbjct: 525 LRFSRDGEILASGSMDNTVRLWDAI--KAFEDLETDDFTTATGHINLPENSQELLLGTY 581 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRK 284 PV FSP +L ++ DG + W+LQT Sbjct: 353 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 384 >5Y88-O nrPDB Length = 451 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 44/150 (29%), Gaps = 10/150 (6%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC-CNFIDNTDLQ 71 + D+ + L S D ++ + + D Y H I T Sbjct: 184 TVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRD-----YYGHLSGVRTVSIHPTLDL 238 Query: 72 IYVGTVQGEILKVDLIGS-PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 I I D+ P + + + C D +++++S D + + D Sbjct: 239 IATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQ--CTPVDPQVVSSSTDATVRLWDVV 296 Query: 131 NYGDGVIAVKNLNSNNTKVKNKI-FTMDTN 159 + + S + F++ + Sbjct: 297 AGKTMKVLTHHKRSVRATALHPKEFSVASA 326 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 62/183 (33%), Gaps = 29/183 (15%) Query: 128 DPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTI 187 D VI+ K+ +++ + NKIF + LIV + + Sbjct: 76 DFSEASQAVISKKDHDTHASAFVNKIFQPEVAEE-LIVNRYEKLLSQRPEWHAPWKLSRV 134 Query: 188 EESGLKYQIRDVALLPKEQEGYACSSID------------------GRVA----VEFFDD 225 L + +R VA+ P + E + S D G V V D Sbjct: 135 INGHLGW-VRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDR 193 Query: 226 QGDDYNSSKRFAFRCHRLNLKDTNLAY-----PVNSIEFSPRHKFLYTAGSDGIISCWNL 280 ++ S+ +C L Y V ++ P + TAG D +I W++ Sbjct: 194 HPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDM 253 Query: 281 QTR 283 +TR Sbjct: 254 RTR 256 >6QX9-4B nrPDB Length = 522 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 34/111 (30%), Gaps = 7/111 (6%) Query: 21 PSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGE 80 PS L T +D S ++ D++A+ L Q D + G + Sbjct: 333 PSGRFLGTTCYDRSWRLW--DLEAQEEILHQEGHSMGVYDIAFHQDGSLAG--TGGLDAF 388 Query: 81 ILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 DL L + + GI + S D +V D R Sbjct: 389 GRVWDLRTGRCIMFLEGHLKEIYGINF--SPNGYHIATGSGDNTCKVWDLR 437 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 53/319 (16%), Positives = 91/319 (28%), Gaps = 44/319 (13%) Query: 11 KDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC--------- 61 IS P+ +L W G ++ +LL +LR H Sbjct: 231 DRPISYCHFSPNSKMLATACWSGLCKLWSVPD----CNLLHTLR-GHNTNVGAIVFHPKS 285 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDLIGS-PSFQALTNNEANLGICRICKYGDDKLIAASW 120 +D D+ + G + L P + + L + Sbjct: 286 TVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMW--HPSGRFLGTTCY 343 Query: 121 DGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 D + D + + + ++ V + F D + + +V R C Sbjct: 344 DRSWRLWDLEAQEE----ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 399 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 E LK +I + P GY ++ G N+ K + R Sbjct: 400 I----MFLEGHLK-EIYGINFSP---NGYHIAT-------------GSGDNTCKVWDLRQ 438 Query: 241 HRLNLKDTNLAYPVNSIEFSPRHK-FLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSV-V 298 R V ++F P H FL T D W +K A + + Sbjct: 439 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498 Query: 299 KIACSDNILCLATSDDTFK 317 I+ ++ + D TFK Sbjct: 499 DISSDGQLIATCSYDRTFK 517 >3JAP-g nrPDB Length = 326 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 54/322 (16%), Positives = 90/322 (27%), Gaps = 83/322 (25%) Query: 24 SLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKH---PLLCCNFIDNTDLQIYVGTVQGE 80 +LL+ S D +L ++ + + H D + Sbjct: 32 NLLVSGSRDKTLISWRLTENEQQFGVPVRSYKGHSHIVQDVVVSADGNYA--VSASWDKT 89 Query: 81 ILKVDL-IGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAV 139 + +L G+ + + + L + K+I+AS D I V + GD + Sbjct: 90 LRLWNLATGNSEARFVGHTGDVLSVA--IDANSSKIISASRDKTIRVWNT--VGDCAYVL 145 Query: 140 KNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDV 199 TKV+ + +D T +G+ +R Sbjct: 146 LGHTDWVTKVRVA-------------------PKNLEDGEVDDGRITFVSAGMDKIVRSW 186 Query: 200 ALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEF 259 +L R+ +F N + P S+ Sbjct: 187 SLNEDSY----------RIEADFIG-----------------HNNYINVVQPSPDGSLA- 218 Query: 260 SPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFKTN 319 +AG DG I WNL+ + NF D + LA S F Sbjct: 219 -------ASAGKDGQIYVWNLKHKSAFMNFD-----------AKDEVFALAFSPSRFWLT 260 Query: 320 AAIDQTIELNASSIYIIFDYEN 341 AA I+ I+D EN Sbjct: 261 AATASGIK--------IYDLEN 274 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 28/84 (33%), Gaps = 4/84 (4%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 + D+ + + + SWD +L ++ + L ID +I Sbjct: 69 VQDVVVSADGNYAVSASWDKTLRLWNLATGNSEARFVG--HTGDVLSV--AIDANSSKII 124 Query: 74 VGTVQGEILKVDLIGSPSFQALTN 97 + I + +G ++ L + Sbjct: 125 SASRDKTIRVWNTVGDCAYVLLGH 148 >4AEZ-A nrPDB Length = 401 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 37/118 (31%), Gaps = 9/118 (7%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 + + ++ +L S G++ + I + LQ D LQ+ Sbjct: 179 VGCLSW--NRHVLSSGSRSGAIHHHDVRIANHQIGTLQG-HSSEVCGLAWRSDG--LQLA 233 Query: 74 VGTVQGEILKVDLIGS-PSFQALTNNEANLGICRICKYGDDKLIA--ASWDGLIEVID 128 G + D S P F +N A + C + + L + D I + Sbjct: 234 SGGNDNVVQIWDARSSIPKFTKTNHNAAVKAVAW-CPWQSNLLATGGGTMDKQIHFWN 290 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 50/130 (38%), Gaps = 10/130 (7%) Query: 7 EQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFID 66 E Y++ +K S L + +G + +Y + Q K L+++ + C + Sbjct: 130 ETDESTYVASVKWSHDGSFLSVGLGNGLVDIYDVESQTK----LRTMAGHQARVGCLSWN 185 Query: 67 NTDLQIYVGTVQGEILKVDL-IGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLI 124 L G+ G I D+ I + L ++ G+ + +L + D ++ Sbjct: 186 RHVLS--SGSRSGAIHHHDVRIANHQIGTLQGHSSEVCGLAW--RSDGLQLASGGNDNVV 241 Query: 125 EVIDPRNYGD 134 ++ D R+ Sbjct: 242 QIWDARSSIP 251 >5WLC-LS nrPDB Length = 594 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 11/94 (11%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLR-YKHPLLCCNF----IDNT 68 I + PSK LLL +D +L +Y D K L+ SL P+ C F + Sbjct: 251 IQSLSFHPSKPLLLTGGYDKTLRIYHID--GKTNHLVTSLHLVGSPIQTCTFYTSLSNQN 308 Query: 69 DLQIYVGTVQGEILKVDLIGSPSFQALTNNEANL 102 I+ + + DL S + LT+++ Sbjct: 309 QQNIFTAGRRRYMHSWDL----SLENLTHSQTAK 338 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 35/106 (33%), Gaps = 18/106 (16%) Query: 245 LKDTNLAYP----VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKI 300 LKD N ++P + S+ F P L T G D + +++ + + S ++ Sbjct: 238 LKDANASHPSHSAIQSLSFHPSKPLLLTGGYDKTLRIYHIDGKTNHLVTSLHLVGSPIQT 297 Query: 301 AC---------SDNILC-----LATSDDTFKTNAAIDQTIELNASS 332 NI S D N QT ++ S Sbjct: 298 CTFYTSLSNQNQQNIFTAGRRRYMHSWDLSLENLTHSQTAKIEKFS 343 >5Z56-q nrPDB Length = 504 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 80/259 (30%), Gaps = 33/259 (12%) Query: 59 LLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIA 117 L C N +I G ++ D L + + + + D + + Sbjct: 227 LDLCPSDTN---KILTGGADKNVVVFDKSSEQILATLKGHTKKVTSV--VFHPSQDLVFS 281 Query: 118 ASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRL 177 AS D I + N + + ++ + T ++ ++ Q F Sbjct: 282 ASPDATIRIWSVPNASCVQVVRAHESA-----VTGLSLHATGD--YLLSSSDDQYWAFSD 334 Query: 178 PLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFA 237 + + + P + ++D ++ + ++ + N Sbjct: 335 IQTGRVLTKVTDETSGCSLTCAQFHPDGLI-FGTGTMDSQIKIWDLKERTNVAN------ 387 Query: 238 FRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSV 297 F H P+ SI FS +L TA D + W+L+ K K + + + Sbjct: 388 FPGHSG---------PITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTL-QLDNNFE 437 Query: 298 VKIAC---SDNILCLATSD 313 VK S L L +D Sbjct: 438 VKSLIFDQSGTYLALGGTD 456 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 76/205 (37%), Gaps = 20/205 (9%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDI--QAKNVDLLQSLRYKHPLLC 61 VQ+ +A + ++ + + + LL +S + F + + + L C Sbjct: 299 VQVVRAHESAVTGLSLHATGDYLLSSS---DDQYWAFSDIQTGRVLTKVTDETSGCSLTC 355 Query: 62 CNFIDNTDLQIY-VGTVQGEILKVDLIGSPSF-QALTNNEANLGICRICKYGDDKLIAAS 119 F + D I+ GT+ +I DL + ++ I L A+ Sbjct: 356 AQF--HPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAF--SENGYYLATAA 411 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQV----QWF 175 D +++ D R + + NN +VK+ IF D + + L +G + Q+ QW Sbjct: 412 DDSSVKLWDLRKLKNFKTLQLD---NNFEVKSLIF--DQSGTYLALGGTDVQIYICKQWT 466 Query: 176 RLPLCEDDNGTIEESGLKYQIRDVA 200 + + +G + + +A Sbjct: 467 EILHFTEHSGLTTGVAFGHHAKFIA 491 Score = 32.0 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 246 KDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDN 305 D + +F P T D I W+L+ R + NF + + IA S+N Sbjct: 345 TDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSEN 403 Query: 306 ILCLATSDD 314 LAT+ D Sbjct: 404 GYYLATAAD 412 >3FM0-A nrPDB Length = 345 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 44/288 (15%), Positives = 97/288 (33%), Gaps = 43/288 (14%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKF-DIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVG 75 + P + L S+D + ++K + V L+ L Sbjct: 67 VAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEG-HENEVKSVAWAPSGNLLA--TC 123 Query: 76 TVQGEILKVDLIGSPSFQALT----NNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 + + ++ ++ ++ + + + + L +AS+D +++ R Sbjct: 124 SRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVW--HPSQELLASASYDDTVKLY--RE 179 Query: 132 YGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESG 191 D + L + + V + F D + RL ++ V+ +R L ++ G SG Sbjct: 180 EEDDWVCCATLEGHESTVWSLAF--DPSGQRLASCSDDRTVRIWRQYLPGNEQGVAC-SG 236 Query: 192 LKYQIRDVALLPKEQEGY---------------ACSSIDGRVAVEFF--DDQGDDYNSSK 234 + + L G+ A ++ G A+ F D D + Sbjct: 237 SDPSWKCICTL----SGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF 292 Query: 235 RFAFRCHRLNLKDTNLAYPVNSIEFSPRH-KFLYTAGSDGIISCWNLQ 281 H+ + +D VN + ++P+ L + DG ++ W Q Sbjct: 293 SLTAHLHQAHSQD------VNCVAWNPKEPGLLASCSDDGEVAFWKYQ 334 >6HQA-B nrPDB Length = 722 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 53/303 (17%), Positives = 110/303 (36%), Gaps = 38/303 (12%) Query: 20 IPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQG 79 +PS + + + LT KF+ + V ++ + ID + L+ + Sbjct: 378 LPSVCMYTFHNTNNDLTCLKFNDDSTMVASG----FQDSFIKLWSIDGSPLRSLLKNDPY 433 Query: 80 EILKVD-LIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIA 138 D + S + + ++ A G+ + LI+ S D + + Y +++ Sbjct: 434 NQQNNDGVAVKGSRRLVGHSGAVYGVDF--SPDNRYLISCSEDKTVRLWSLDTYT-CLVS 490 Query: 139 VKNLNSNNTKVKN-KIF-TMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQI 196 K +S+ VK + T S Q RL C+ +G + Sbjct: 491 YKGHSSSVWDVKFSPMGHYFATA----------SHDQTARLWSCDHIYPLRIFAGHLNDV 540 Query: 197 RDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNS 256 V P + SS D ++ ++ C R+ + + +N Sbjct: 541 DCVEFHPNSTYLFTGSS----------DKTARMWDIARG---ECVRVFMGHSG---AINC 584 Query: 257 IEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACS--DNILCLATSDD 314 + SP ++L +AG D ++ W++ T ++IK S+ +A S +L +D+ Sbjct: 585 LAVSPDGRWLASAGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVSTGADN 644 Query: 315 TFK 317 + + Sbjct: 645 SVR 647 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 22/163 (13%), Positives = 49/163 (30%), Gaps = 6/163 (3%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 + ++ P+ + L S D + ++ + + V + D L Sbjct: 540 VDCVEFHPNSTYLFTGSSDKTARMWDIA-RGECVRVFMG-HSGAINCLAVSPDGRWLA-- 595 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVID-PRNY 132 + D+ +A+ + + L++ D + V D +N Sbjct: 596 SAGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVSTGADNSVRVWDVKKNT 655 Query: 133 GDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWF 175 + +N + K T D + IV N+ +F Sbjct: 656 NSPSAQPEPINDVTAQGIQK-KTEDLRRRKEIVATNDHMSVYF 697 Score = 30.9 bits (68), Expect = 0.85, Method: Composition-based stats. Identities = 10/115 (8%), Positives = 22/115 (19%), Gaps = 11/115 (9%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGT 76 + P L+ S D ++ ++ D + + Sbjct: 459 VDFSPDNRYLISCSEDKTVRLWSLD--TYTCLVSYKGHSSSVWDVKFSPMGHYFA--TAS 514 Query: 77 VQGEILKVDLIGSPSFQALT---NNEANLGICRICKYGDDKLIAASWDGLIEVID 128 + N+ + L S D + D Sbjct: 515 HDQTARLWSCDHIYPLRIFAGHLNDVDCVEFH----PNSTYLFTGSSDKTARMWD 565 >4LG8-A nrPDB Length = 354 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 80/259 (30%), Gaps = 33/259 (12%) Query: 59 LLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIA 117 L C N +I G ++ D L + + + + D + + Sbjct: 77 LDLCPSDTN---KILTGGADKNVVVFDKSSEQILATLKGHTKKVTSV--VFHPSQDLVFS 131 Query: 118 ASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRL 177 AS D I + N + + ++ + T ++ ++ Q F Sbjct: 132 ASPDATIRIWSVPNASCVQVVRAHESA-----VTGLSLHATGD--YLLSSSDDQYWAFSD 184 Query: 178 PLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFA 237 + + + P + ++D ++ + ++ + N Sbjct: 185 IQTGRVLTKVTDETSGCSLTCAQFHPDGLI-FGTGTMDSQIKIWDLKERTNVAN------ 237 Query: 238 FRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSV 297 F H P+ SI FS +L TA D + W+L+ K K + + + Sbjct: 238 FPGHSG---------PITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTL-QLDNNFE 287 Query: 298 VKIAC---SDNILCLATSD 313 VK S L L +D Sbjct: 288 VKSLIFDQSGTYLALGGTD 306 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 76/205 (37%), Gaps = 20/205 (9%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDI--QAKNVDLLQSLRYKHPLLC 61 VQ+ +A + ++ + + + LL +S + F + + + L C Sbjct: 149 VQVVRAHESAVTGLSLHATGDYLLSSS---DDQYWAFSDIQTGRVLTKVTDETSGCSLTC 205 Query: 62 CNFIDNTDLQIY-VGTVQGEILKVDLIGSPSF-QALTNNEANLGICRICKYGDDKLIAAS 119 F + D I+ GT+ +I DL + ++ I L A+ Sbjct: 206 AQF--HPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAF--SENGYYLATAA 261 Query: 120 WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQV----QWF 175 D +++ D R + + NN +VK+ IF D + + L +G + Q+ QW Sbjct: 262 DDSSVKLWDLRKLKNFKTLQLD---NNFEVKSLIF--DQSGTYLALGGTDVQIYICKQWT 316 Query: 176 RLPLCEDDNGTIEESGLKYQIRDVA 200 + + +G + + +A Sbjct: 317 EILHFTEHSGLTTGVAFGHHAKFIA 341 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 246 KDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDN 305 D + +F P T D I W+L+ R + NF + + IA S+N Sbjct: 195 TDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSEN 253 Query: 306 ILCLATSDD 314 LAT+ D Sbjct: 254 GYYLATAAD 262 >6EMK-B nrPDB Length = 303 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 46/287 (16%), Positives = 90/287 (31%), Gaps = 32/287 (11%) Query: 8 QAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDN 67 Q ++ ++I K LL T+ ++ +Y N + DN Sbjct: 29 QHSDSQVNRLEITNDKK-LLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDN 87 Query: 68 TDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVI 127 + + G I D+ + +N + + +LI+ DG I + Sbjct: 88 RWM--VTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEV--VIHPNQGELISCDRDGNIRIW 143 Query: 128 DPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTI 187 D + + + +M ++ S L + +P D + Sbjct: 144 DL-GENQCTHQLTPED----DTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLK 198 Query: 188 EESGLKYQIRDVA--LLPKEQEGYACSSIDGRVAVEFFDDQ---GDDYNSSKRFAFRCHR 242 + + + LL + + A S D V DD + +R+ + C Sbjct: 199 PVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDC-- 256 Query: 243 LNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 FS +L TA SD + W+L TR+ ++ + Sbjct: 257 ---------------AFSADSAYLVTASSDHYVRLWDLSTREIVRQY 288 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 21/62 (33%), Gaps = 2/62 (3%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTR--KKIKNFAKFNEDSVVKIACSDNILCLA 310 PVN + P L + DG I W+L + +A ++L A Sbjct: 118 PVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAA 177 Query: 311 TS 312 + Sbjct: 178 NT 179 >3W15-A nrPDB Length = 368 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 50/309 (16%), Positives = 93/309 (30%), Gaps = 35/309 (11%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGT 76 + + + L+ + G L + + D + V++ L ++ + Q+ V Sbjct: 26 LAVAAGSNFGLVGN--GKLFILEIDRSGRIVEVNSFLTQDCLFDLAW-NESHENQVLVAQ 82 Query: 77 VQGEILKVDLIGSP-SFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDP-RNYGD 134 G + D +E + C +++SWDG I++ P R Sbjct: 83 GDGTLRLFDTTFKEFPIAIFKEHEREVFSCNWNLVNRQNFLSSSWDGSIKIWSPLRKQSL 142 Query: 135 GVIAVKNLNSN------NTKVKNKIFTMDTNSSRLIVGMNNSQVQ--------------- 173 + + L N + K + +R V Sbjct: 143 MTLTPRPLEITKMVDPLNAIILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYAS 202 Query: 174 --WFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYN 231 RLP ++ N + SGL+ D A +D A+ +D + + N Sbjct: 203 LFDIRLPSGKNQNNFLVHSGLEALTCDFN--KYRPYVVATGGVDN--AIRIWDIRMLNKN 258 Query: 232 SSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHK-FLYTAGSDGIISCWNLQTRKKIKNFA 290 + C +N + + +SP H L +A D W + K Sbjct: 259 PGQLHNSSC--INEIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETY 316 Query: 291 KFNEDSVVK 299 K N K Sbjct: 317 KTNSTDATK 325 >5WYJ-BC nrPDB Length = 817 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 52/136 (38%), Gaps = 11/136 (8%) Query: 1 MQIVQIEQ----APKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYK 56 +QI+++ + A + I+ + + P+ S+ S+D + ++ + L R Sbjct: 477 VQIIKVSEYTRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGL 536 Query: 57 HPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKL 115 + C + D + + + L + L + A I K +L Sbjct: 537 WDVSFCQY----DKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINK--QKQL 590 Query: 116 IAASWDGLIEVIDPRN 131 I+ DGLI++ D + Sbjct: 591 ISCGADGLIKIWDCSS 606 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 45/145 (31%), Gaps = 20/145 (13%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVY-------KFDIQAKNVDLLQSLR-Y 55 V+I + +D ++ + + S D + V+ KFDI AK + ++ Sbjct: 381 VEIYEGHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAV 440 Query: 56 KHPLLCCNFIDNTDLQIYVGTVQGEILKVDL---IGSPSFQALTNNEANLGICR------ 106 P + + + I K + S Q + +E Sbjct: 441 GLPNIVS---KGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINAL 497 Query: 107 ICKYGDDKLIAASWDGLIEVIDPRN 131 D AS+D ++ + N Sbjct: 498 SVSPNDSIFATASYDKTCKIWNLEN 522 >6BX3-B nrPDB Length = 412 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 14/105 (13%), Positives = 29/105 (27%), Gaps = 5/105 (4%) Query: 16 DIKIIPSKSLLLITSWDGSLTVYKFDI-QAKNVD-LLQSLRYKHPLLCCNFIDNTDLQIY 73 ++ P L + +G+L +Y D + V + + D L Sbjct: 30 CLQFSPCGDYLALGCANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLL--L 87 Query: 74 VGTVQGEILKVDLIG-SPSFQALTNNEANLGICRICKYGDDKLIA 117 + I DL S + + + G + + Sbjct: 88 TSSRDWSIKLWDLSKPSKPLKEIRFDSPIWGCQWLDAKRRLCVAT 132 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA 301 P+ SI +SP + L T+ D I W+L K K + DS + Sbjct: 73 PITSIAWSPDGRLLLTSSRDWSIKLWDLS--KPSKPLKEIRFDSPIWGC 119 >5WLC-LO nrPDB Length = 923 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 43/130 (33%), Gaps = 23/130 (17%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYK---------FDIQAKNVDLLQSLRYKHPLLCC 62 D + + P S ++ S DG + V+ F+ +V +Q + + Sbjct: 346 DSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVM--- 402 Query: 63 NFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDG 122 + ++ G + DLI +F+ T E C + + A S D Sbjct: 403 ----------FSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDN 452 Query: 123 L-IEVIDPRN 131 I V + Sbjct: 453 FDIHVWSVQT 462 Score = 35.1 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 Q++ + +S + S+L SWD ++ ++ +++ V+ ++ Y L Sbjct: 464 QLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEV--YSDVLAL 521 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDL 86 D ++ V T++G+I ++ Sbjct: 522 SMRPDGK--EVAVSTLKGQISIFNI 544 Score = 34.7 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 43/117 (36%), Gaps = 7/117 (5%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ ++ ++ +S DG++ + I+ +N + C +D + + Sbjct: 389 SVTAVQFAKRGQVMFSSSLDGTVRAWDL-IRYRNFRTFTG--TERIQFNCLAVDPSGEVV 445 Query: 73 YVGTVQG-EILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVI 127 G++ +I + AL+ + C + L +ASWD I + Sbjct: 446 CAGSLDNFDIHVWSVQTGQLLDALSGHEGPVS--CLSFSQENSVLASASWDKTIRIW 500 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 49/280 (17%), Positives = 85/280 (30%), Gaps = 45/280 (16%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN-FIDNTDLQI 72 I+ + +L TS D S ++ D + KN L + H F + +I Sbjct: 149 ITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKN--LAATTFNGHRDYVMGAFFSHDQEKI 206 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNY 132 Y + G + + PS +E + + I Sbjct: 207 YTVSKDGAVFVWEFTKRPSDDDDNESEDDDKQEEVDISKYSWRIT--------------- 251 Query: 133 GDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGL 192 K + K K T + L VG + FRL D + S Sbjct: 252 -------KKHFFYANQAKVKCVTFHPATRLLAVGFTSG---EFRLYDLPDFTLIQQLSMG 301 Query: 193 KYQIRDVALLPKEQEGYACSSID-GRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLA 251 + + V++ + E A S G++ V + + F Sbjct: 302 QNPVNTVSV-NQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFD-------------- 346 Query: 252 YPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAK 291 NS+ +SP + TA DG I W++ + + F + Sbjct: 347 -STNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEE 385 >5I2T-A nrPDB Length = 742 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 43/130 (33%), Gaps = 23/130 (17%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYK---------FDIQAKNVDLLQSLRYKHPLLCC 62 D + + P S ++ S DG + V+ F+ +V +Q + + Sbjct: 371 DSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVM--- 427 Query: 63 NFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDG 122 + ++ G + DLI +F+ T E C + + A S D Sbjct: 428 ----------FSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDN 477 Query: 123 L-IEVIDPRN 131 I V + Sbjct: 478 FDIHVWSVQT 487 Score = 35.1 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 2 QIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLC 61 Q++ + +S + S+L SWD ++ ++ +++ V+ ++ Y L Sbjct: 489 QLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEV--YSDVLAL 546 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDL 86 D ++ V T++G+I ++ Sbjct: 547 SMRPDGK--EVAVSTLKGQISIFNI 569 Score = 34.7 bits (78), Expect = 0.063, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 43/117 (36%), Gaps = 7/117 (5%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ ++ ++ +S DG++ + I+ +N + C +D + + Sbjct: 414 SVTAVQFAKRGQVMFSSSLDGTVRAWDL-IRYRNFRTFTG--TERIQFNCLAVDPSGEVV 470 Query: 73 YVGTVQG-EILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVI 127 G++ +I + AL+ + C + L +ASWD I + Sbjct: 471 CAGSLDNFDIHVWSVQTGQLLDALSGHEGPVS--CLSFSQENSVLASASWDKTIRIW 525 Score = 31.2 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 49/280 (17%), Positives = 85/280 (30%), Gaps = 45/280 (16%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN-FIDNTDLQI 72 I+ + +L TS D S ++ D + KN L + H F + +I Sbjct: 174 ITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKN--LAATTFNGHRDYVMGAFFSHDQEKI 231 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNY 132 Y + G + + PS +E + + I Sbjct: 232 YTVSKDGAVFVWEFTKRPSDDDDNESEDDDKQEEVDISKYSWRIT--------------- 276 Query: 133 GDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGL 192 K + K K T + L VG + FRL D + S Sbjct: 277 -------KKHFFYANQAKVKCVTFHPATRLLAVGFTSG---EFRLYDLPDFTLIQQLSMG 326 Query: 193 KYQIRDVALLPKEQEGYACSSID-GRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLA 251 + + V++ + E A S G++ V + + F Sbjct: 327 QNPVNTVSV-NQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFD-------------- 371 Query: 252 YPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAK 291 NS+ +SP + TA DG I W++ + + F + Sbjct: 372 -STNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEE 410 >5FVM-C nrPDB Length = 303 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 55/291 (18%), Positives = 103/291 (35%), Gaps = 40/291 (13%) Query: 8 QAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL--RYKHPLLCCNFI 65 Q ++ ++I K L G L V +DI++ N + + S + Sbjct: 29 QHADSQVNRLEITSDKKYLAA---AGHLHVRLYDIRSNNPNPVSSFEGHKGNVTSIAFQQ 85 Query: 66 DNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE 125 +N + + G I D+ + +N + +LI+ DG I Sbjct: 86 ENRWM--VSSSEDGTIKVWDVRSPSVQRNYKHNAPVNEVA--IHPNQGELISCDQDGNIR 141 Query: 126 VIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCED--- 182 + D + + NT +++ ++ ++ S L+ G N +R+P D Sbjct: 142 IWDL-GENQCTNQLTPED--NTPLQS--LSVASDGSMLVAGNNKGNCYVWRMPHHTDAST 196 Query: 183 -DNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQ---GDDYNSSKRFAF 238 + T +S KY R LL + + A S D V +D + +R+ + Sbjct: 197 LEPVTKFKSHTKYITR--VLLSADVKNLATCSADHTARVWNIEDNYQLETTLDGHQRWVW 254 Query: 239 RCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 C FS +L TA SD + W+L T + ++ + Sbjct: 255 DC-----------------AFSADSAYLVTACSDHYVRLWDLSTSEIVRQY 288 >5UZ7-B nrPDB Length = 351 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 38/126 (30%), Gaps = 10/126 (7%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 Y+S + + ++TS G T +DI+ + + D ++ Sbjct: 156 YLSCCRFLDDNQ--IVTS-SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD---TRL 209 Query: 73 YV-GTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 +V G D+ Q T + IC + S D + D R Sbjct: 210 FVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF--PNGNAFATGSDDATCRLFDLR 267 Query: 131 NYGDGV 136 + + Sbjct: 268 ADQELM 273 >5K0Y-T nrPDB Length = 329 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 49/278 (17%), Positives = 93/278 (33%), Gaps = 29/278 (10%) Query: 16 DIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVG 75 + +L S D S ++ + + L L+ + C F ++ ++ Sbjct: 57 CVDADWDTKHVLTGSADNSCRLWDCETGKQ----LALLKTNSAVRTCGFDFGGNIIMFST 112 Query: 76 TVQ-GEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE-VIDPRNYG 133 Q G V + NNE + I D K+ +A W L E +I G Sbjct: 113 DKQMGYQCFVSFFDLRDPSQIDNNEPYMKI----PCNDSKITSAVWGPLGECIIAGHESG 168 Query: 134 DGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLK 193 + LN + K + + +S ++ + ++ F ++ + + L+ Sbjct: 169 E-------LNQYSAKSGEVLVNVKEHSRQINDIQLSREMTMFVTASKDNTAKLFDSTTLE 221 Query: 194 YQI-------RDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLK 246 +Q R++A L E G+ A++ RF Sbjct: 222 HQKTFRTEPPRELAALSPNYEHVVVGG--GQEAMDVTTTSTRIGKFEARFFHLAFEEEFG 279 Query: 247 DTNLAY-PVNSIEFSPRHKFLYTAGSDG--IISCWNLQ 281 + P+NS+ F P K + G DG I ++ Q Sbjct: 280 RVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQ 317 >4A11-B nrPDB Length = 408 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 66/187 (35%), Gaps = 15/187 (8%) Query: 97 NNEANLGICRICKYGDDKLIAAS-WDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFT 155 + + + D + +S +D ++V D + + + + Sbjct: 98 HRYSVETVQWY--PHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYS----HHMSP 151 Query: 156 MDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTI--EESGLKYQIRDVALLPKEQEGYACSS 213 + T + VG +VQ LC+ +G+ G + +I V+ P+ A +S Sbjct: 152 VSTKHCLVAVGTRGPKVQ-----LCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATAS 206 Query: 214 IDGRVAV-EFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSD 272 D RV + + G + + + +T VN + F+ L T G+D Sbjct: 207 ADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTD 266 Query: 273 GIISCWN 279 + WN Sbjct: 267 NRMRLWN 273 >4L9O-A nrPDB Length = 349 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 46/301 (15%), Positives = 102/301 (33%), Gaps = 23/301 (7%) Query: 4 VQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCN 63 V I A D I D + L S D ++ +++ D + + + Sbjct: 62 VTIGNAHDDLIHDAVLDYYGRRLATCSSDKTIKIFEIDGENQRLVETLIGHEGPVWQVAW 121 Query: 64 FIDNTDLQIYVGTVQGEILKV---DLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW 120 + + + G++L + + + + + + + L+ AS Sbjct: 122 AHPKFGVILASCSYDGKVLIWKEDNGVWNKVAEHSVHQASVNSVSWAPHEYGPVLLCASS 181 Query: 121 DGLIEVIDPRNYGDG--VIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLP 178 DG I +++ ++ G ++ + N I D N+ R + G ++ V+ +R Sbjct: 182 DGKISIVEFKDGGALEPIVIQGHAIGVNAASWAPISLPD-NTRRFVSGGCDNLVKIWR-- 238 Query: 179 LCEDDNGTIEE----SGLKYQIRDVALLPKE-QEGYACSSIDGRVAVEFFDDQGDDYNSS 233 +D T E G +RDVA P + Y ++ R + + D + Sbjct: 239 -YDDAAKTFIEEEAFQGHSDWVRDVAWSPSRLSKSYIATASQDRTVLIWTKDGKSN---- 293 Query: 234 KRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFN 293 + + L +S L +G D ++ W + K ++ + + Sbjct: 294 -----KWEKQPLTKEKFPDVCWRASWSLSGNVLAISGGDNKVTLWKENIQGKWESAGEVD 348 Query: 294 E 294 + Sbjct: 349 Q 349 >5OQL-d nrPDB Length = 446 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 8/89 (8%) Query: 48 DLLQSLRYKHPLLCCNF--IDNTDLQIYVGTVQGEILKVDLIG--SPSFQALTNNEANLG 103 L L H + N+ I G+ G + DL +++ +N G Sbjct: 56 PFLGQLGNGHVQGVYSMCKDKNSLNCIASGSGDGVVKVWDLTTRDEETWRVAAHNNIVKG 115 Query: 104 ICRICKYGDDKLIAASWDGLIEVIDPRNY 132 + D KL++ + DG I++ DP Sbjct: 116 LTFT---NDKKLLSCATDG-IKLWDPYAS 140 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 31/77 (40%), Gaps = 3/77 (3%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 + D++ P+ L+ S+D ++ +++ + D+ + R + +D+ I Sbjct: 286 VMDVEFSPTGEELVSGSYDRTIRLWR-RDAGHSRDVYHTKRMQRVFRTMWTMDSKY--IL 342 Query: 74 VGTVQGEILKVDLIGSP 90 G+ G + S Sbjct: 343 TGSDDGNVRLWRANASE 359 >6CHG-D nrPDB Length = 439 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 28/97 (28%), Gaps = 7/97 (7%) Query: 16 DIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLL---QSLRYKHPLLCCNFIDNTDLQI 72 +K P L + +G++ +Y D K + +L + C D L Sbjct: 32 CVKFSPRGDYLAVGCSNGAIIIYDMD-SLKPIAMLGTHSGAHTRSVQSVCWSNDGRYL-- 88 Query: 73 YVGTVQGEILKVDLIG-SPSFQALTNNEANLGICRIC 108 + D+ + FQ + + Sbjct: 89 WSSGRDWYAKLWDMTQPTKCFQQYKFDGPLWSCHVVR 125 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 250 LAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIK---NFAKFNEDSVVKIA-CSDN 305 + ++FSPR +L S+G I +++ + K I + + SV + +D Sbjct: 26 VPVAAVCVKFSPRGDYLAVGCSNGAIIIYDMDSLKPIAMLGTHSGAHTRSVQSVCWSNDG 85 Query: 306 ILCLATSDDTF 316 ++ D + Sbjct: 86 RYLWSSGRDWY 96 >5K1B-B nrPDB Length = 677 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDS----VVKIACSDNILCL 309 VN+++ P L+TAG D II W++ K+ A + + + C+ L Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 310 ATSDDTFK 317 A+SD T K Sbjct: 93 ASSDTTVK 100 Score = 31.2 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 14/129 (10%), Positives = 46/129 (35%), Gaps = 12/129 (9%) Query: 5 QIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRY----KHPLL 60 ++E+ ++ ++ +++ P+ + L D + ++ + ++ + + +L Sbjct: 24 EVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVL 83 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQAL-TNNEANLGICRICKYGDDKLIAAS 119 CCN + + + + L T+ + + + + +A Sbjct: 84 CCN-----GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAK--DKELVASAG 136 Query: 120 WDGLIEVID 128 D I + D Sbjct: 137 LDRQIFLWD 145 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 45/133 (33%), Gaps = 12/133 (9%) Query: 12 DYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQ 71 D+++DI + + L+ S D ++ V+ + + L++ + D Sbjct: 76 DWVNDIVLCCNGKTLISASSDTTVKVWNAH-KGFCMSTLRT-HKDYVKALAYAKDKEL-- 131 Query: 72 IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDK--------LIAASWDGL 123 + + +I D+ + A N + +++ S + + Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKV 191 Query: 124 IEVIDPRNYGDGV 136 + V DPR + Sbjct: 192 LRVWDPRTCAKLM 204 >4J0X-A nrPDB Length = 451 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL 53 +I+ + IP ++ + SW GSL V+K ++ +LL L Sbjct: 352 WITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGEL 392 >3ACP-A nrPDB Length = 417 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 33/104 (31%), Gaps = 5/104 (4%) Query: 5 QIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNF 64 +I+QA I+ +K PS L+ +S D L ++ + Sbjct: 130 EIDQAHVSEITKLKFFPSGEALISSSQDMQLKIWSVKDGSN--PRTLIGHRATVTDIAII 187 Query: 65 IDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNE-ANLGICRI 107 + + ++ G I + + E + G+ I Sbjct: 188 DRGRN--VLSASLDGTIRLWECGTGTTIHTFNRKENPHDGVNSI 229 >5WLC-SG nrPDB Length = 573 Score = 36.3 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 13 YISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL 53 +I+ + IP ++ + SW GSL V+K ++ +LL L Sbjct: 474 WITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGEL 514 >3BG0-A nrPDB Length = 316 Score = 36.3 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 49/298 (16%), Positives = 95/298 (31%), Gaps = 35/298 (11%) Query: 3 IVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCC 62 I ++ + +D I D ++ + L S D S+ ++ + + Sbjct: 5 INTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVA 64 Query: 63 NFIDNTDLQIYVGTVQGEILKV---DLIGSPSFQALTNNEANLGICRICKYGDDKLI--A 117 + + +++ + S + ++ + +C D LI Sbjct: 65 WAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCW--APHDYGLILAC 122 Query: 118 ASWDGLIEVIDPRNYGDGVIAVKN--LNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWF 175 S DG I ++ G + N V + + G + ++ F Sbjct: 123 GSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRF 182 Query: 176 RLPLC---------EDDNGTIEESGLKYQ---IRDVALLPK---EQEGYACSSIDGRVAV 220 C E+D EE L+ +RDVA P A S DGRV + Sbjct: 183 ASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFI 242 Query: 221 EFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCW 278 DD + S K H+ N ++++ + + L +G D ++ W Sbjct: 243 WTCDDASSNTWSPKLL----HKFNDVVWHVSWSITA-------NILAVSGGDNKVTLW 289 >1NR0-A nrPDB Length = 611 Score = 35.9 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 10/123 (8%) Query: 210 ACSSIDGRVAVEFFDDQGDDYNSSKRFA---FRCHRLNLKDTNLAYPVNSIEFSPRHKFL 266 A +S+D + + F G D N+ F F+ + T V+S+ ++P Sbjct: 149 AMNSVDFKPSRPFRIISGSDDNTVAIFEGPPFKFKSTFGEHTKF---VHSVRYNPDGSLF 205 Query: 267 YTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFK-TNAAIDQT 325 + G DG I +N K F +DS+ +A S ++ L S D K +A+ D+T Sbjct: 206 ASTGGDGTIVLYNGVDGTKTGVFE---DDSLKNVAHSGSVFGLTWSPDGTKIASASADKT 262 Query: 326 IEL 328 I++ Sbjct: 263 IKI 265 Score = 35.1 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 59/174 (33%), Gaps = 16/174 (9%) Query: 50 LQSLRYKHPLLCCNFIDNTDLQ-IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRIC 108 + +RY H + D + ++ +G I D+ S + + A + I I Sbjct: 316 IDQVRYGHNKAITALSSSADGKTLFSADAEGHINSWDISTGISNRVFPDVHATM-ITGIK 374 Query: 109 KYGDDKLIAASWDGLIEVIDPRNYG-DGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGM 167 L SWD ++V+ G D AV N S+ + + + V Sbjct: 375 TTSKGDLFTVSWDDHLKVVPAGGSGVDSSKAVANKLSS-----QPLGLAVSADGDIAVAA 429 Query: 168 NNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVE 221 + + +G + E + Y VAL +Q A D +V V Sbjct: 430 CYKHIAIY-------SHGKLTEVPISYNSSCVALSNDKQF-VAVGGQDSKVHVY 475 Score = 31.2 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 17/144 (11%), Positives = 44/144 (30%), Gaps = 16/144 (11%) Query: 5 QIEQAPKDY-ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSL-RYKHPLLCC 62 ++ + P Y S + + K + + D + VYK +V ++++ Sbjct: 441 KLTEVPISYNSSCVALSNDKQFVAVGGQDSKVHVYKL--SGASVSEVKTIVHPAEITSVA 498 Query: 63 NFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALT------NNEANLGICRICKYGDDKLI 116 + ++ + + +F+ + + + +L Sbjct: 499 FSNNGA----FLVATDQSRKVIPYSVANNFELAHTNSWTFHTAKVACVSW--SPDNVRLA 552 Query: 117 AASWDGLIEVIDPRNYGDGVIAVK 140 S D + V + D I +K Sbjct: 553 TGSLDNSVIVWNMNKPSDHPIIIK 576 Score = 30.5 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 38/223 (17%), Positives = 73/223 (32%), Gaps = 30/223 (13%) Query: 74 VGTVQGEILKVDLIGSPSF---QALTNNEANLGICRICKYGDDKLIAASWDGLIEV---- 126 G V G + D + + I + K IAA +G Sbjct: 76 SGDVHGNVRIWDTTQTTHILKTTIPVFSGPVKDISW---DSESKRIAAVGEGRERFGHVF 132 Query: 127 -IDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNG 185 D + + N + + R+I G +++ V F P + + Sbjct: 133 LFDTGTSNGNLTGQ-------ARAMNSVDFKPSRPFRIISGSDDNTVAIFEGPPFKFKST 185 Query: 186 TIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNL 245 E + + +R + +A + DG + + + + +K F +L Sbjct: 186 FGEHTKFVHSVR----YNPDGSLFASTGGDGTIVLY------NGVDGTKTGVFE--DDSL 233 Query: 246 KDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKN 288 K+ + V + +SP + +A +D I WN+ T K K Sbjct: 234 KNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKT 276 >6HHQ-h nrPDB Length = 319 Score = 35.9 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 45/253 (17%), Positives = 86/253 (33%), Gaps = 42/253 (16%) Query: 72 IYVGTVQGEILKVDLIGSPS-----FQALTNNEANLGICRICKYGDDKLIAASWDGLIEV 126 + + ++ L G ++ + + C + G ++ASWD + + Sbjct: 33 LLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADG-AYALSASWDKTLRL 91 Query: 127 IDP---RNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDD 183 D Y V ++ S + K + + + V Q L Sbjct: 92 WDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQC----LATLLGH 147 Query: 184 NGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFA----FR 239 N + + V ++P E+ + D + +D+ + +F F Sbjct: 148 NDWVSQ---------VRVVPNEK-----ADDDSVTIISAGNDKMVKAWNLNQFQIEADFI 193 Query: 240 CHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVK 299 H N +N++ SP + +AG DG I WNL +K + + +D V Sbjct: 194 GHNSN---------INTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLS--AQDEVFS 242 Query: 300 IACSDNILCLATS 312 +A S N LA + Sbjct: 243 LAFSPNRYWLAAA 255 Score = 35.9 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 40/120 (33%), Gaps = 10/120 (8%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFI-DNTDLQI 72 + D + + L SWD +L ++ + H + D I Sbjct: 68 VQDCTLTADGAYALSASWDKTLRLWDVA-TGETY----QRFVGHKSDVMSVDIDKKASMI 122 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRI--CKYGDDKL--IAASWDGLIEVID 128 G+ I + G L +N+ + + K DD + I+A D +++ + Sbjct: 123 ISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWN 182 >6GMH-W nrPDB Length = 305 Score = 35.9 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 43/247 (17%), Positives = 84/247 (34%), Gaps = 50/247 (20%) Query: 93 QALTNNEANLGICR--ICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVK 150 Q +++A + K + ++ S D L++V R+ + + +L + V Sbjct: 11 QEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRD--ERLDLQWSLEGHQLGVV 68 Query: 151 N-------KIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLP 203 + I + + + + + Q + D T+ A P Sbjct: 69 SVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTL------------AFSP 116 Query: 204 KEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRH 263 Q A + G+V + + +Y+ R F + SI +SP Sbjct: 117 DSQY-LATGTHVGKVNIFGVESGKKEYSLDTRGKF---------------ILSIAYSPDG 160 Query: 264 KFLYTAGSDGIISCWNLQTRKKIKNFA---------KFNEDSVVKIACSDNILCLATSDD 314 K+L + DGII+ +++ T K + F+ DS + + SD+ D Sbjct: 161 KYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDD--GYIKIYD 218 Query: 315 TFKTNAA 321 N A Sbjct: 219 VQHANLA 225 >6BX3-A nrPDB Length = 314 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 53/341 (15%), Positives = 100/341 (29%), Gaps = 103/341 (30%) Query: 15 SDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDL-LQSLRYKHPLLCCNFIDNTDLQ-- 71 + KI P L IT L + +DI + V L + + C D + Sbjct: 16 TCAKISPDGQFLAITQ---GLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATA 72 Query: 72 -------------------------------------IYVGTVQGEILKVD-LIGSPSFQ 93 ++ ++ I D L GS Sbjct: 73 SDDFSVEIIHLSYGLLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKT 132 Query: 94 ALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKI 153 ++EA + + + L + S+DGLI + D + + I Sbjct: 133 ISAHSEAVVSVD-VPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPI 191 Query: 154 FTM--DTNSSRLIVGMNNSQVQ-WFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYA 210 + N+ L+V + V+ W + C +R + P E+ Sbjct: 192 SQVKFSENARYLLVKSLDGVVKIWDCIGGCV--------------VRTFQVQPLEK---- 233 Query: 211 CSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAG 270 + ++F + + D + ++ E Sbjct: 234 -GVLHHSCGMDFLNPE--------------------DGSTPLVISGYE------------ 260 Query: 271 SDGIISCWNLQTRK--KIKNFAKFNEDSVV-KIACSDNILC 308 +G I CWN T+ ++ + + ++ S V I C NI+C Sbjct: 261 -NGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFGNIMC 300 >5WLC-LU nrPDB Length = 489 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 33/191 (17%), Positives = 67/191 (35%), Gaps = 16/191 (8%) Query: 12 DYISDIKIIPS-KSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDL 70 D I+ +K + +L T D S+ +Y + ++Q++R C Sbjct: 220 DNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNA---ICW-NPMEAF 275 Query: 71 QIYVGTVQGEILKVDLIG-SPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVID 128 D+ S S + A + + D+++ S+D I + Sbjct: 276 NFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDF--SPTGDEIVTGSYDKSIRIYK 333 Query: 129 PRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDN--GT 186 + I + +VK + +S +I G ++ V+ +R E N T Sbjct: 334 TNHGHSREIYHTKRMQHVFQVKYSM-----DSKYIISGSDDGNVRLWRSKAWERSNVKTT 388 Query: 187 IEESGLKYQIR 197 E++ L+Y + Sbjct: 389 REKNKLEYDEK 399 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 11 KDYIS---DIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDN 67 KD++S D+ P+ ++ S+D S+ +YK + + ++ + R +H +D+ Sbjct: 302 KDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKTN-HGHSREIYHTKRMQHVFQVKYSMDS 360 Query: 68 TDLQIYVGTVQGEILKV 84 I G+ G + Sbjct: 361 KY--IISGSDDGNVRLW 375 Score = 27.4 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 16/25 (64%) Query: 266 LYTAGSDGIISCWNLQTRKKIKNFA 290 L T +DG+I WN+ TR++ +F Sbjct: 83 LATGSADGVIKYWNMSTREEFVSFK 107 >5M89-A nrPDB Length = 329 Score = 35.5 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 28/73 (38%), Gaps = 6/73 (8%) Query: 242 RLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA 301 R + A PV + P + L + G D ++L+T +++ A+ D+ + Sbjct: 121 RESATFQTHAGPVTGLAVHPGGRILASVGVDKSFVFYDLETGERV---ARGYADAALTTC 177 Query: 302 C---SDNILCLAT 311 N+ T Sbjct: 178 AFHPDGNLFAAGT 190 >5OQL-J nrPDB Length = 912 Score = 35.5 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 57/350 (16%), Positives = 113/350 (32%), Gaps = 47/350 (13%) Query: 7 EQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQA-KNVDLLQSLRYKHPLLCCNFI 65 ++A + + I P + LL S D ++T++ + + +L+ H LL Sbjct: 228 KEAHESNVQCIAYSPEQHALLSGSRDKTMTLWLWRDGIWQGTPMLR-----HELLESVGF 282 Query: 66 DNTDLQIYVGTVQGEILKVDLIGSPSFQALTN--NEANLGICRICKYGDDKLIAASWDGL 123 N +Y G + D + +E + + ++ A D Sbjct: 283 LNEGKWMYSAGTSGVLRIWDTTTHHEITKKQDAKSEGEAILSAVSLPERSLILCAQADFT 342 Query: 124 IEVI------DPRNYGDGVIAVKNLNSNNT-----KVKN-----KIFTMDTNSSRL-IVG 166 + + D + +G++ + T + + + TNS + IV Sbjct: 343 LVLYRVPSPADVVSSSEGILLEPFRRISGTHDEILDLTYILPDQSMMAIATNSEDIRIVS 402 Query: 167 MNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPK-EQEGY--ACSSIDGRVAVEFF 223 + ++Q C + + L D+ + + G+ A S D + Sbjct: 403 VKDAQAYSEDNAECRSGSYFGHDVALLKGHEDIVMSLDVDWSGHWIASGSKDNTARLWRV 462 Query: 224 DDQGDDYNSSKRFAFRCHRLNLKDTNLAY---PVNSIEF-----SPRHKFLYTAGSDGII 275 D + Y F H ++ L P NS F P FL + D + Sbjct: 463 DPANNSYTCYAVFT--GHLESVGAVALPKVVPPANSEAFKNPLDHP-PAFLISGSQDRFV 519 Query: 276 SCWN----LQTRKKIKNF-AKFNEDSVVK---IACSDNILCLATSDDTFK 317 + LQ K+ + + D + I+ + + A+ D T K Sbjct: 520 QKRDIPRQLQKGGKLTSSLRRLAHDKDINALDISPNGKLFASASQDKTVK 569 Score = 35.1 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 32/87 (36%), Gaps = 8/87 (9%) Query: 8 QAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAK------NVDLLQSLRYKHPLLC 61 Q + IS + I PS S L++ S ++ +Y I + ++ Sbjct: 58 QGDGEPISTLTITPSGSHLIVCSRSLTMRIYSLAISPDYDSVEPTLVRTTKPHATPVVVL 117 Query: 62 CNFIDNTDLQIYVGTVQGEILKVDLIG 88 +D T + G G I D+IG Sbjct: 118 --AVDRTSTLLATGAADGAIKIWDIIG 142 Score = 35.1 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 19/138 (13%), Positives = 46/138 (33%), Gaps = 18/138 (13%) Query: 9 APKDYISDIKIIPSKSLLLITSWDGSLTVYKFD-IQAKNVDLLQS-----LRYKHP-LLC 61 A I+ + I P+ L S D ++ ++ + ++ + + +R+ Sbjct: 542 AHDKDINALDISPNGKLFASASQDKTVKIWDVEKLEVQGILRGHKRGVWTVRFAPLNTPV 601 Query: 62 CNFIDNTDLQ---IYVGTVQGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLI- 116 + + G+ I +L + ++ L + + DD + Sbjct: 602 IQGEQGSVSGRGVVLTGSGDKTIKLWNLSDYTCIRTFEGHSHNVLKVVWLHISRDDSITK 661 Query: 117 ------AASWDGLIEVID 128 +A D L++V D Sbjct: 662 TKVQFASAGADTLVKVWD 679 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 16/127 (12%), Positives = 38/127 (29%), Gaps = 16/127 (12%) Query: 22 SKSLLLITSWDGSLTVYKFDIQAKNVDLLQS--LRYKHPLLCCNFIDNTDLQIY-VGTVQ 78 + L+ S D + Q + L S R H + + +++ + Sbjct: 506 PPAFLISGSQDRFVQKRDIPRQLQKGGKLTSSLRRLAHDKDINALDISPNGKLFASASQD 565 Query: 79 GEILKVDLI-------------GSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIE 125 + D+ G + + N + + G ++ S D I+ Sbjct: 566 KTVKIWDVEKLEVQGILRGHKRGVWTVRFAPLNTPVIQGEQGSVSGRGVVLTGSGDKTIK 625 Query: 126 VIDPRNY 132 + + +Y Sbjct: 626 LWNLSDY 632 >6ID0-T nrPDB Length = 514 Score = 35.1 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 16/136 (11%), Positives = 38/136 (27%), Gaps = 9/136 (6%) Query: 19 IIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY-VGTV 77 + L D + + + + + + H + + + + Sbjct: 254 VSTRSPYLFSCGEDKQVKCWDLE-----YNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 308 Query: 78 QGEILKVDLIGSPSFQALT-NNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGV 136 D+ S L+ + A + C+ + ++I S D I + D V Sbjct: 309 DSTARIWDVRTKASVHTLSGHTNAVATVR--CQAAEPQIITGSHDTTIRLWDLVAGKTRV 366 Query: 137 IAVKNLNSNNTKVKNK 152 + S V + Sbjct: 367 TLTNHKKSVRAVVLHP 382 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 36/221 (16%), Positives = 73/221 (33%), Gaps = 51/221 (23%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGT 76 + + P+ +L+ S D + ++ +A L + C + QI G+ Sbjct: 294 LDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC----QAAEPQIITGS 349 Query: 77 VQGEILKVDLIGSPSFQALTNNEA------------------------------------ 100 I DL+ + LTN++ Sbjct: 350 HDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNL 409 Query: 101 ---NLGICRICKYGDDKLIAASWDGLIEVIDPR---NYGDGVIAVKNLNSNNTKVKNKIF 154 N I + D L++ + +G + + D R N+ AV+ + ++ Sbjct: 410 SGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACA 469 Query: 155 TMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQ 195 D + SRL+ + ++ +R EDD T E + ++ Sbjct: 470 -FDQSESRLLTAEADKTIKVYR----EDDTATEETHPVSWK 505 Score = 30.9 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 38/94 (40%), Gaps = 16/94 (17%) Query: 196 IRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVN 255 +R +A+ P Q + S D + + + +L L T V Sbjct: 207 VRCIAVEPGNQ-WFVTGSADRTIKI---------------WDLASGKLKLSLTGHISTVR 250 Query: 256 SIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNF 289 + S R +L++ G D + CW+L+ K I+++ Sbjct: 251 GVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHY 284 >5WLC-LN nrPDB Length = 776 Score = 34.7 bits (78), Expect = 0.057, Method: Composition-based stats. Identities = 54/270 (20%), Positives = 104/270 (38%), Gaps = 39/270 (14%) Query: 68 TDLQIYVGTVQGEILKVDLIGSPSFQALT----NNEANLGICRICKYGDD-KLIAASWDG 122 +DL++ +G G I + + FQ + + + G+C G+ +L + Sbjct: 63 SDLRLAIGRSNGNIEIWN-PRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGST 121 Query: 123 LIEVIDPRNYGDGVIAVKNLNSN--NTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLC 180 ++ D + L + N+ V I D+ L VG +N V L Sbjct: 122 VVTEWD-------LATGLPLRNYDCNSGVIWSISINDSQDK-LSVGCDNGTVV---LIDI 170 Query: 181 EDDNGTIEESG--LKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRF-A 237 G +E ++ + R + L K+ + DGR+ + + Q +D N + Sbjct: 171 SGGPGVLEHDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRI--WSAQKNDENMGRLLHT 228 Query: 238 FRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSV 297 + + + T V S+ + PR + + S G I W+ Q ++F + D Sbjct: 229 MKVDKAKKEST----LVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDAD-- 282 Query: 298 VKIACSDNILCLAT-SDDTFKTNAAIDQTI 326 +LCL T +D+ + +A +D+ I Sbjct: 283 --------VLCLTTDTDNNYVFSAGVDRKI 304 >5YZG-2 nrPDB Length = 646 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 40/238 (16%), Positives = 79/238 (33%), Gaps = 39/238 (16%) Query: 72 IYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASW--DGLIEVIDP 129 I + G + I + + + ++LG+ + + S D ++V D Sbjct: 104 IITASHDGHVKFWKKI-EEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDV 162 Query: 130 RNYGDGVIAVK---NLNS---NN-TKVKNKIFTMDTNSSRLIVG--MNNSQVQWFRLPLC 180 N+ + + + + ++ ++ + ++Q Sbjct: 163 VNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQP-------- 214 Query: 181 EDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRC 240 + S L QIR + A S D +E++ +Y K + Sbjct: 215 LHIFDKLHTSPLT-QIRLNPVYK------AVVSSDKSGMIEYWTGPPHEYKFPKNVNWEY 267 Query: 241 HRLNLKDTNL-------AYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAK 291 DT+L AYP S+ FSP K + T GSD + + T K ++ F + Sbjct: 268 K----TDTDLYEFAKCKAYPT-SVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDE 320 >6J6H-n nrPDB Length = 455 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 47/115 (40%), Gaps = 18/115 (15%) Query: 64 FIDNTDLQIYVGTVQGEILKVDLIGS----PSFQALTNNEANLGICRICKYGDDK--LIA 117 F+ T I G I D FQ +N+ + ++ +D ++ Sbjct: 170 FLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQG--HNKPIKAL----RFTEDCQSFLS 223 Query: 118 ASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQV 172 +S+D +++ D V +LNS V+++ TN IVG++NS++ Sbjct: 224 SSFDRSVKIWDTETGK--VKTRLHLNSTPADVESR----PTNPHEFIVGLSNSKI 272 >5US9-A nrPDB Length = 541 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 129 PRNYGDGVIAVKNLNSNNTKVKNKIFT-MDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTI 187 + G ++AVK N++ + I + D L ++QW++ P ++NG I Sbjct: 312 TSDTGAWMVAVKPENASIDTGMSGIGSGFDPPQGSLAPTNLEYKIQWYQTPQGTNNNGNI 371 Query: 188 EESGLKYQIRDVALLPKEQEGYACSS 213 + +RD AL Q Y S Sbjct: 372 ISNQPLSMLRDQALFRGNQTTYNLCS 397 >5K19-A nrPDB Length = 569 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 47/141 (33%), Gaps = 15/141 (10%) Query: 157 DTNSS-RLIVGMNNSQVQWFRLPLCEDDNGTIEESGL-KYQIRDVALLPKEQEGYACSSI 214 T S L+VG + QVQ E EE + K ++ V +P + + + Sbjct: 111 ATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHS 170 Query: 215 DGRVAVEFFDDQGDDYNSSKRF-----AFRCHRLNLKDTNLAY--------PVNSIEFSP 261 G + + + + +F H K T +N FSP Sbjct: 171 SGNMYLYNVEHTCGTTAPHYQLLKQGESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSP 230 Query: 262 RHKFLYTAGSDGIISCWNLQT 282 KFL DG + +N + Sbjct: 231 DGKFLACVSQDGFLRVFNFDS 251 >1PI6-A nrPDB Length = 615 Score = 33.2 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 7/92 (7%) Query: 238 FRCHRLNLKDTNLAYPVNSIEFSPRHK-FLYTAGSDGIISCWNLQTRKKIKNFAKFNEDS 296 F+ + V +EFSP F+ T GSD ISC++ ++ + +K ++ Sbjct: 193 FKFSASDRTHHKQGSFVRDVEFSPDSGEFVITVGSDRKISCFDGKSGEFLKYIE--DDQE 250 Query: 297 VVKIACSDNILCLATSDDTFKTNAAIDQTIEL 328 V+ I L+ D D TI + Sbjct: 251 PVQ----GGIFALSWLDSQKFATVGADATIRV 278 >4XFV-A nrPDB Length = 792 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 33/86 (38%), Gaps = 10/86 (11%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIY 73 ++ ++ +P ++ S D + ++KF + + Y ++ + + + I Sbjct: 66 VTCVRFVPDSDFMVSASEDHHVKIWKFTDYSHLQCIQTIQHYSKTIVALSALPSL---IS 122 Query: 74 VGTVQGEILKVDLIGSPSFQALTNNE 99 VG G I Q + N+E Sbjct: 123 VGCADGTISIWR-------QNIQNDE 141 >4XYI-A nrPDB Length = 430 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 14/150 (9%) Query: 186 TIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNL 245 +I+ + + R A++ Q ++ V+ + D S A +C + + Sbjct: 222 SIDVAPVSVYHRHTAVVNDLQFHLQHEALLTSVSDDCTLQIHDTRLPSSSSASQCVKAHE 281 Query: 246 KDTNLAYPVNSIEFSPRHKF-LYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACS- 303 + PVN + F+P + + L TA +D ++ W+L+ + + + +ED V + S Sbjct: 282 Q------PVNGVAFNPFNDYLLATASADHTVALWDLRRLNQRLHTLEGHEDEVYNVQWSP 335 Query: 304 -DNILCLATSDD-----TFKTNAAIDQTIE 327 D + + +S D + +QT+E Sbjct: 336 HDEPILVTSSTDRRVCVWDLSKIGEEQTVE 365 >5LCW-Q nrPDB Length = 374 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 48/137 (35%), Gaps = 12/137 (8%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +Q++Q+EQ P +YIS + I + L + + + ++ Q + ++ Sbjct: 92 LQLLQMEQ-PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS--HSARVGS 148 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVD--LIGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + G+ G I D + +++ G+ L + Sbjct: 149 LSW----NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRW--APDGRHLASG 202 Query: 119 SWDGLIEVIDPRNYGDG 135 D L+ V P G+G Sbjct: 203 GNDNLVNVW-PSAPGEG 218 >4GGA-A nrPDB Length = 420 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 48/137 (35%), Gaps = 12/137 (8%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +Q++Q+EQ P +YIS + I + L + + + ++ Q + ++ Sbjct: 138 LQLLQMEQ-PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS--HSARVGS 194 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVD--LIGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + G+ G I D + +++ G+ L + Sbjct: 195 LSW----NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRW--APDGRHLASG 248 Query: 119 SWDGLIEVIDPRNYGDG 135 D L+ V P G+G Sbjct: 249 GNDNLVNVW-PSAPGEG 264 >5G04-R nrPDB Length = 499 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 48/137 (35%), Gaps = 12/137 (8%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +Q++Q+EQ P +YIS + I + L + + + ++ Q + ++ Sbjct: 217 LQLLQMEQ-PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS--HSARVGS 273 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVD--LIGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + G+ G I D + +++ G+ L + Sbjct: 274 LSW----NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRW--APDGRHLASG 327 Query: 119 SWDGLIEVIDPRNYGDG 135 D L+ V P G+G Sbjct: 328 GNDNLVNVW-PSAPGEG 343 >5MC6-j nrPDB Length = 397 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 24/42 (57%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNED 295 V S+ F+ + L +AG DG + W+++T+++I +D Sbjct: 294 VMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDD 335 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 115 LIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRL 163 L +A WDG + D + I N++ ++ +++ I +D + L Sbjct: 306 LCSAGWDGKLRFWDVKTKER--ITTLNMHCDDIEIEEDILAVDEHGDSL 352 >4N14-A nrPDB Length = 314 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 48/137 (35%), Gaps = 12/137 (8%) Query: 1 MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL 60 +Q++Q+EQ P +YIS + I + L + + + ++ Q + ++ Sbjct: 54 LQLLQMEQ-PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS--HSARVGS 110 Query: 61 CCNFIDNTDLQIYVGTVQGEILKVD--LIGSPSFQALTNNEANLGICRICKYGDDKLIAA 118 + G+ G I D + +++ G+ L + Sbjct: 111 LSW----NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRW--APDGRHLASG 164 Query: 119 SWDGLIEVIDPRNYGDG 135 D L+ V P G+G Sbjct: 165 GNDNLVNVW-PSAPGEG 180 >4G56-B nrPDB Length = 357 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 50/124 (40%), Gaps = 7/124 (5%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKH---PLLCCNFIDNTDL 70 ++D+ + K +L+ + G++ +++ ++ +++ + + +Y+H F D T Sbjct: 97 VTDVAWVSEKGILVASD-SGAVELWEI-LEKESLLVNKFAKYEHDDIVKTLSVFSDGT-- 152 Query: 71 QIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPR 130 Q G + DL ++ + + + C D ++ DG I + D R Sbjct: 153 QAVSGGKDFSVKVWDLSQKAVLKSYNAHSSEVNCVAACPGKDTIFLSCGEDGRILLWDTR 212 Query: 131 NYGD 134 Sbjct: 213 KPKP 216 >3ODT-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 40/111 (36%), Gaps = 8/111 (7%) Query: 18 KIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTV 77 + +++ SWD + V+K + V LQ+ + ++ + + Sbjct: 109 SLSFQDGVVISGSWDKTAKVWK---EGSLVYNLQA-HNASVWDA-KVVSFSENKFLTASA 163 Query: 78 QGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVID 128 I + +N+ + + D I+ S DGLI+++D Sbjct: 164 DKTIKLWQNDKVIKTFSGIHNDVVRHLAVV---DDGHFISCSNDGLIKLVD 211 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 54/159 (33%), Gaps = 28/159 (17%) Query: 30 SWDGSLTVYKFDIQAKNVDLLQSLRYKHPLL--CCNFIDNTDLQIYVGT---VQGEILKV 84 S DG++ ++ D Q L + L C + +L ++ G + G L Sbjct: 36 SRDGTVRLWSKDDQW----LGTVVYTGQGFLNSVC-YDSEKELLLFGGKDTMINGVPLFA 90 Query: 85 DLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNS 144 P + + + + + D +I+ SWD +V + V NL + Sbjct: 91 TSGEDPLYTLIGHQGNVCSL----SFQDGVVISGSWDKTAKVWKEGS------LVYNLQA 140 Query: 145 NNTKV--------KNKIFTMDTNSSRLIVGMNNSQVQWF 175 +N V F + + + N+ ++ F Sbjct: 141 HNASVWDAKVVSFSENKFLTASADKTIKLWQNDKVIKTF 179 >5CXB-B nrPDB Length = 369 Score = 30.9 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSD 313 V S+ P L T G DG + W L T +++ K N D V N + + Sbjct: 24 VRSVAIDPTGVALATGGDDGTVRVWELLTGRQVW-SVKLNGDEAV------NTVRWRPTK 76 Query: 314 DTFKTNAAIDQTIEL 328 DTF AA + I L Sbjct: 77 DTFILAAAAGEDIFL 91 >5N4A-A nrPDB Length = 771 Score = 30.9 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 8/73 (10%), Positives = 12/73 (16%), Gaps = 2/73 (2%) Query: 47 VDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICR 106 V+ + D T L G + G + I Sbjct: 96 VEKSIEGHKGACISLRWSYDGTALA--TAGEDGSVKIWSRNGMLRSTLAQADSPVYSIVW 153 Query: 107 ICKYGDDKLIAAS 119 S Sbjct: 154 AYDCDQLCYCTGS 166 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 25/68 (36%), Gaps = 7/68 (10%) Query: 67 NTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICR-------ICKYGDDKLIAAS 119 N +++ + I K +++G P + T + + G D A Sbjct: 23 NVWNELFTCSDDQTIHKWNMLGEPEQKVSTLDAYFTDMHWYPVSSKKTQAGGTDVFAVAC 82 Query: 120 WDGLIEVI 127 DG ++++ Sbjct: 83 TDGSVKIL 90 >3F3P-A nrPDB Length = 351 Score = 30.9 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 27/63 (42%), Gaps = 6/63 (9%) Query: 67 NTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIA-ASWDGLIE 125 ++D I V + + +L S ++ + + I ++IA AS+D ++ Sbjct: 30 SSDQHIKVFKLDKDTSNWELSDSWR----AHDSSIVAIDW-ASPEYGRIIASASYDKTVK 84 Query: 126 VID 128 + + Sbjct: 85 LWE 87 >5MWJ-A nrPDB Length = 337 Score = 30.5 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 25/49 (51%) Query: 242 RLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFA 290 R+ + T+ A ++ SP K ++ SDG I+ W+L + ++ F Sbjct: 132 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQ 180 >3EI3-B nrPDB Length = 383 Score = 30.5 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 237 AFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSD-GIISCWNLQTRKK 285 + + ++L+ + V S+E+ P H GS G I W+ + K Sbjct: 59 SLKSYKLHRTASPFDRRVTSLEWHPTHPTTVAVGSKGGDIILWDYDVQNK 108 >5OQL-X nrPDB Length = 630 Score = 30.5 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 19/35 (54%) Query: 14 ISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVD 48 I+ ++ +P L+ SWDG + V++ + ++ Sbjct: 466 ITALRTLPYSDLIFSGSWDGCIRVWRLSEDKRKLE 500 >2AJB-A nrPDB Length = 728 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 49/132 (37%), Gaps = 20/132 (15%) Query: 7 EQAPKDYISDIKIIPSKSLLLITSWDGSLT-VYKFDIQAKNVDLLQSLRYKHPLLCCNFI 65 +P ++ +I+P S+L+ + +T V + I + + Q+ + C++ Sbjct: 237 TLSPNASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYS---IIDICDYD 293 Query: 66 DNTDLQI--------------YVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYG 111 ++T I +VG + G+ ++ ++N E IC Sbjct: 294 ESTGRWISSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDK 353 Query: 112 DDK--LIAASWD 121 + + +W+ Sbjct: 354 SNCTFITKGAWE 365 >5WYJ-BE nrPDB Length = 939 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 29/77 (37%), Gaps = 6/77 (7%) Query: 253 PVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC---SDNILCL 309 V I ++ + + G DGI+ ++ + K D+ + S ++ L Sbjct: 504 AVTGISLDGMNRKMVSCGLDGIVGFYDFNKSTLL---GKLKLDAPITAMVYHRSSDLFAL 560 Query: 310 ATSDDTFKTNAAIDQTI 326 A D + A+ Q + Sbjct: 561 ALDDLSIVVIDAVTQRV 577 >6CVZ-A nrPDB Length = 351 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 32/100 (32%), Gaps = 12/100 (12%) Query: 17 IKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRY---KHP--LLCCNFIDNT--- 68 + P K+ I S ++ Y+ D + Q + LL N I + Sbjct: 229 VTYRPDKNHTTIRSVLMEMS-YRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPEN 287 Query: 69 DLQIYVGTVQG---EILKVDLIGSPSFQALTNNEANLGIC 105 D I V T L D Q L ++ L IC Sbjct: 288 DGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDIC 327 >3C9C-A nrPDB Length = 432 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 41/125 (32%), Gaps = 12/125 (9%) Query: 17 IKIIPSKS-LLLITSWDGSLTVYKFDIQAKN--VDLLQSLRYKH---PLLCCNFIDNTDL 70 + P+ + LL S D ++ ++ + K V +++ H + + L Sbjct: 189 LSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESL 248 Query: 71 QIYVGTVQGEILKVDL----IGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEV 126 V +++ D PS + + Y + L S D + + Sbjct: 249 FGSVAD-DQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLS-FNPYSEFILATGSADKTVAL 306 Query: 127 IDPRN 131 D RN Sbjct: 307 WDLRN 311 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 10/75 (13%), Positives = 22/75 (29%), Gaps = 3/75 (4%) Query: 14 ISDIKIIPSKSLLLI-TSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ + P +L S D ++ ++ + +S N + Sbjct: 282 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES-HKDEIFQVQWSPHNETILA 340 Query: 73 YVGTVQGEILKVDLI 87 GT + DL Sbjct: 341 SSGT-DRRLHVWDLS 354 >6F1U-h nrPDB Length = 612 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/140 (12%), Positives = 49/140 (35%), Gaps = 24/140 (17%) Query: 14 ISDIKIIPSKSL--LLITSWDGSLTVYKFDIQAKNVDLLQSLRYK-----------HPLL 60 + + ++ +++ L+ S DG + + D+ + D ++ + + Sbjct: 358 VYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGD 417 Query: 61 CCNFIDNTDL-QIYVGTVQGEILKVDLIGSPSFQALTNNEANLGIC---RICKYGDDKL- 115 NF+ ++ +Y G + S F+ + GI + L Sbjct: 418 VNNFVVGSEEGSVYTACRHGSKAGI----SEMFEG--HQGPITGIHCHAAVGAVDFSHLF 471 Query: 116 IAASWDGLIEVIDPRNYGDG 135 + +S+D +++ +N Sbjct: 472 VTSSFDWTVKLWSTKNNKPL 491 >5Y1U-A nrPDB Length = 456 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 39/116 (33%), Gaps = 13/116 (11%) Query: 26 LLITSWDGSLTVYKFDI---QAKNVDLLQSLRYKH---PLLCCNFIDNTDLQIYVGTVQG 79 LL S D ++ ++ + K VD +++ H + + L V Sbjct: 224 LLSASDDHTICLWDISAVPKEGKVVD-AKTIFTGHTAVVEDVSWHLLHESLFGSVAD-DQ 281 Query: 80 EILKVDLIGS----PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 +++ D + PS + + Y + L S D + + D RN Sbjct: 282 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLS-FNPYSEFILATGSADKTVALWDLRN 336 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 10/75 (13%), Positives = 22/75 (29%), Gaps = 3/75 (4%) Query: 14 ISDIKIIPSKSLLLI-TSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ + P +L S D ++ ++ + +S N + Sbjct: 307 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES-HKDEIFQVQWSPHNETILA 365 Query: 73 YVGTVQGEILKVDLI 87 GT + DL Sbjct: 366 SSGT-DRRLNVWDLS 379 >3CFV-B nrPDB Length = 414 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 40/116 (34%), Gaps = 13/116 (11%) Query: 26 LLITSWDGSLTVYKFDI---QAKNVDLLQSLRYKH---PLLCCNFIDNTDLQIYVGTVQG 79 LL S D ++ ++ + + K VD +++ H + + L V Sbjct: 195 LLSASDDHTVCLWDINAGPKEGKIVD-AKAIFTGHSAVVEDVAWHLLHESLFGSVAD-DQ 252 Query: 80 EILKVDLIGS----PSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRN 131 +++ D + PS + + Y + L S D + + D RN Sbjct: 253 KLMIWDTRSNTTSKPSHLVDAHTAEVNCLS-FNPYSEFILATGSADKTVALWDLRN 307 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 26/87 (29%), Gaps = 3/87 (3%) Query: 14 ISDIKIIPSKSLLLI-TSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQI 72 ++ + P +L S D ++ ++ + +S N + Sbjct: 278 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFES-HKDEIFQVHWSPHNETILA 336 Query: 73 YVGTVQGEILKVDLIGSPSFQALTNNE 99 GT + DL Q+ + E Sbjct: 337 SSGT-DRRLNVWDLSKIGEEQSAEDAE 362 >5WLC-LW nrPDB Length = 554 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 21/44 (47%) Query: 249 NLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKF 292 + PVNSI ++ T G+D + W+++ K++ + Sbjct: 272 SARGPVNSIAIDRSGYYMATTGADRSMKIWDIRNFKQLHSVESL 315 >5WBU-D nrPDB Length = 328 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Query: 254 VNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIAC 302 + S+ F +++YT G D W+L++R ++ F ++ + C Sbjct: 90 IASVGFHEDGRWMYTGGEDCTARIWDLRSRN-LQCQRIFQVNAPINCVC 137 >3IH9-A nrPDB Length = 456 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 208 GYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLN 244 G ++ GRV + F + D+ +S R C RL+ Sbjct: 263 GGVLGALPGRVGIGVFSPRLDEVGNSARGVLACRRLS 299 >4X33-B nrPDB Length = 333 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 30/78 (38%), Gaps = 3/78 (3%) Query: 202 LPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSP 261 L ++Q+ + + ++ ++ N+ + F H L +P+ + Sbjct: 214 LKQQQKRHNLVVLCMWTSIHLWN---ARLNTVESFGRGTHSQLFPQERLDFPIVGVATGS 270 Query: 262 RHKFLYTAGSDGIISCWN 279 H L TA +G C+N Sbjct: 271 EHGILTTANQEGKSHCYN 288 >4D4O-A nrPDB Length = 427 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 30/78 (38%), Gaps = 3/78 (3%) Query: 202 LPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSP 261 L ++Q+ + + ++ ++ N+ + F H L +P+ + Sbjct: 216 LKQQQKRHNLVVLCMWTSIHLWN---ARLNTVESFGRGTHSQLFPQERLDFPIVGVATGS 272 Query: 262 RHKFLYTAGSDGIISCWN 279 H L TA +G C+N Sbjct: 273 EHGILTTANQEGKSHCYN 290 >5CXC-A nrPDB Length = 510 Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 43/123 (34%), Gaps = 8/123 (6%) Query: 18 KIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFID---NTDLQIYV 74 I + + S TV D+ V + +L HPLL + + T + Sbjct: 318 AIFDPRDRTVAYSASQDHTVRTLDLTTGQV--VSTLTLTHPLLSLSALTRAGTTSPLLAA 375 Query: 75 GTVQGEILKVDLIGSPSFQALT--NNEANLGICRICKY-GDDKLIAASWDGLIEVIDPRN 131 GT I VD S + ++ AN + + L++ S DG V D R+ Sbjct: 376 GTSARHITMVDPRASSATTSVMTLRGHANKVVSLSPSPENEYSLVSGSHDGTCRVWDLRS 435 Query: 132 YGD 134 Sbjct: 436 VRP 438 >5WJC-A nrPDB Length = 430 Score = 27.8 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 29/80 (36%), Gaps = 8/80 (10%) Query: 52 SLRYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYG 111 +H L + D+ LQI+ + E + + + + + I + Sbjct: 242 QFHPQHEALLASVSDDCTLQIHDTRLNPE--------EEAPKVIQAHSKAINAVAINPFN 293 Query: 112 DDKLIAASWDGLIEVIDPRN 131 D L AS D + + D RN Sbjct: 294 DYLLATASADKTVALWDLRN 313 >2OLS-A nrPDB Length = 794 Score = 27.4 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 20/52 (38%) Query: 54 RYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGIC 105 Y P+ D D ++Y+ + E +K G+ + + N +C Sbjct: 310 HYGRPMDIEWGRDGLDGKLYILQARPETVKSQEEGNRNLRRFAINGDKTVLC 361 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.128 0.351 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,135,389 Number of Sequences: 36641 Number of extensions: 469407 Number of successful extensions: 1811 Number of sequences better than 10.0: 112 Number of HSP's better than 10.0 without gapping: 99 Number of HSP's successfully gapped in prelim test: 66 Number of HSP's that attempted gapping in prelim test: 1254 Number of HSP's gapped (non-prelim): 524 length of query: 341 length of database: 10,336,785 effective HSP length: 98 effective length of query: 243 effective length of database: 6,745,967 effective search space: 1639269981 effective search space used: 1639269981 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)