BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P25774 (331 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2C0Y-A nrPDB 662 0.0 4P6E-A nrPDB 469 e-133 4BS5-A nrPDB 383 e-107 7PCK-A nrPDB 363 e-101 1CJL-A nrPDB 319 9e-88 3HWN-A nrPDB 272 1e-73 2O6X-A nrPDB 271 3e-73 3QT4-A nrPDB 259 8e-70 6BKI-A nrPDB 259 1e-69 3QJ3-A nrPDB 259 1e-69 3OF9-A nrPDB 257 4e-69 5JA7-A nrPDB 256 7e-69 3KFQ-A nrPDB 256 1e-68 2VHS-A nrPDB 241 4e-64 1CQD-A nrPDB 216 1e-56 1IWD-A nrPDB 209 1e-54 1ICF-A nrPDB 209 2e-54 3P5W-A nrPDB 205 2e-53 1AEC-A nrPDB 204 4e-53 2ACT-A nrPDB 201 5e-52 2PNS-A nrPDB 200 8e-52 4YYR-A nrPDB 199 2e-51 1S4V-A nrPDB 199 2e-51 1O0E-A nrPDB 198 3e-51 6CZS-A nrPDB 195 2e-50 3F75-A nrPDB 193 1e-49 3BCN-A nrPDB 192 1e-49 2FO5-A nrPDB 191 3e-49 4YYQ-A nrPDB 189 1e-48 1NB3-A nrPDB 188 2e-48 5A24-A nrPDB 187 5e-48 4YYW-A nrPDB 186 2e-47 6MIS-A nrPDB 182 1e-46 5EF4-A nrPDB 178 3e-45 4QRX-A nrPDB 176 9e-45 2BDZ-A nrPDB 176 2e-44 1YAL-A nrPDB 174 5e-44 2B1M-A nrPDB 174 5e-44 3U8E-A nrPDB 166 1e-41 6EXO-A nrPDB 166 1e-41 1PCI-A nrPDB 163 1e-40 2CIO-A nrPDB 159 1e-39 4PI3-A nrPDB 153 9e-38 1PPO-A nrPDB 153 1e-37 1GEC-E nrPDB 150 7e-37 3IOQ-A nrPDB 146 1e-35 5I4H-A nrPDB 142 3e-34 3BPM-A nrPDB 137 5e-33 3BPF-A nrPDB 137 6e-33 5JT8-A nrPDB 137 6e-33 1M6D-A nrPDB 128 3e-30 5I4H-B nrPDB 117 6e-27 1JQP-A nrPDB 116 2e-26 3PDF-A nrPDB 111 5e-25 1XKG-A nrPDB 110 9e-25 3PBH-A nrPDB 102 2e-22 5VCN-A nrPDB 102 2e-22 5VPK-A nrPDB 101 4e-22 3CBK-A nrPDB 100 1e-21 1EF7-A nrPDB 100 2e-21 1DEU-A nrPDB 99 2e-21 1CPJ-A nrPDB 99 3e-21 1MIR-A nrPDB 97 1e-20 4I05-A nrPDB 92 2e-19 5OGQ-A nrPDB 92 4e-19 4I04-A nrPDB 90 2e-18 4HWY-A nrPDB 84 7e-17 2DCB-A nrPDB 80 8e-16 4OEL-A nrPDB 72 5e-13 4CDF-B nrPDB 71 6e-13 1CSB-B nrPDB 70 1e-12 5FPW-A nrPDB 64 1e-10 1SP4-B nrPDB 63 2e-10 3CH2-X nrPDB 62 3e-10 4OEM-B nrPDB 55 3e-08 4CI7-A nrPDB 52 3e-07 4D59-A nrPDB 52 4e-07 2L95-A nrPDB 41 7e-04 3OIS-A nrPDB 38 0.006 4K7C-A nrPDB 33 0.21 5WDK-A nrPDB 32 0.29 5B04-A nrPDB 32 0.41 4UYP-A nrPDB 30 1.1 1HP1-A nrPDB 29 2.7 4WD1-A nrPDB 29 3.0 2CB5-A nrPDB 28 7.5 4P1X-A nrPDB 27 8.6 4F3Z-A nrPDB 27 8.7 >2C0Y-A nrPDB Length = 315 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/315 (99%), Positives = 314/315 (99%) Query: 17 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 76 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG Sbjct: 1 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 60 Query: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC 136 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC Sbjct: 61 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC 120 Query: 137 GACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK 196 GA WAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK Sbjct: 121 GAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK 180 Query: 197 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH 256 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH Sbjct: 181 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH 240 Query: 257 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 316 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK Sbjct: 241 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 300 Query: 317 GNHCGIASFPSYPEI 331 GNHCGIASFPSYPEI Sbjct: 301 GNHCGIASFPSYPEI 315 >4P6E-A nrPDB Length = 230 Score = 469 bits (1206), Expect = e-133, Method: Compositional matrix adjust. Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 109 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 168 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV Sbjct: 1 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 60 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 228 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 120 Query: 229 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL 288 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL Sbjct: 121 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL 180 Query: 289 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI Sbjct: 181 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >4BS5-A nrPDB Length = 225 Score = 383 bits (983), Expect = e-107, Method: Compositional matrix adjust. Identities = 181/225 (80%), Positives = 200/225 (88%), Gaps = 1/225 (0%) Query: 108 KSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNL 167 +S NR LPD+VDWREKGCVTEVKYQGSCGACWAFSAVGALE QLKLKTGKL+SLSAQNL Sbjct: 1 RSYSNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNL 60 Query: 168 VDCSTE-KYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSK 226 VDCS E KYGNKGC GG+MT AFQYIIDN GI++DASYPYKAMD+KC Y+SK RAATCS+ Sbjct: 61 VDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSR 120 Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG 286 Y +LP+G ED LKEAVA KGPVSVG+DA H SFF Y+SGVY +PSCT NVNHGVLVVGYG Sbjct: 121 YIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYG 180 Query: 287 DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 L+GK+YWLVKNSWG NFG++GYIRMARN NHCGIAS+ SYPEI Sbjct: 181 TLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >7PCK-A nrPDB Length = 314 Score = 363 bits (931), Expect = e-101, Method: Compositional matrix adjust. Identities = 178/317 (56%), Positives = 224/317 (70%), Gaps = 6/317 (1%) Query: 18 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 77 L+ + LD HW LWKKT+ KQY K +E RRLIWEKNLK++ +HNLE S+G+H+Y+L M Sbjct: 1 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 60 Query: 78 NHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135 NHLGDMTSEEV+ M+ L+VP R + Y PDSVD+R+KG VT VK QG Sbjct: 61 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 120 Query: 136 CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195 CG+CWAFS+VGALE QLK KTGKL++LS QNLVDC +E N GC GG+MT AFQY+ N Sbjct: 121 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---NDGCGGGYMTNAFQYVQKN 177 Query: 196 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 255 +GIDS+ +YPY ++ C Y+ +AA C Y E+P G E LK AVA GPVSV +DA Sbjct: 178 RGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDAS 237 Query: 256 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 314 SF Y GVYY+ SC + N+NH VL VGYG G ++W++KNSWG N+G +GYI MAR Sbjct: 238 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 297 Query: 315 NKGNHCGIASFPSYPEI 331 NK N CGIA+ S+P++ Sbjct: 298 NKNNACGIANLASFPKM 314 >1CJL-A nrPDB Length = 312 Score = 319 bits (818), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 161/321 (50%), Positives = 218/321 (67%), Gaps = 19/321 (5%) Query: 21 DPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHL 80 D +L+ W WK + + Y NEE RR +WEKN+K + LHN E+ G HS+ + MN Sbjct: 1 DHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAF 59 Query: 81 GDMTSEEVMSLMSSL--RVPSQ---WQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135 GDMTSEE +M+ L R P + +Q + Y++ P SVDWREKG VT VK QG Sbjct: 60 GDMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEA------PRSVDWREKGYVTPVKNQGQ 113 Query: 136 CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195 CG+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+GCNGG M AFQY+ DN Sbjct: 114 CGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPE-GNEGCNGGLMDYAFQYVQDN 172 Query: 196 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 255 G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV +DA Sbjct: 173 GGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAG 231 Query: 256 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFGEEGYI 310 H SF Y+ G+Y+EP C +++++HGVLVVGYG + +G +YWLVKNSWG +G GY+ Sbjct: 232 HESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYV 291 Query: 311 RMARNKGNHCGIASFPSYPEI 331 +MA+++ NHCGIAS SYP + Sbjct: 292 KMAKDRRNHCGIASAASYPTV 312 >3HWN-A nrPDB Length = 258 Score = 272 bits (696), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 137/265 (51%), Positives = 184/265 (69%), Gaps = 18/265 (6%) Query: 77 MNHLGDMTSEEVMSLMSSL--RVPSQ---WQRNITYKSNPNRILPDSVDWREKGCVTEVK 131 MN GDMTSEE +M+ R P + +Q + Y++ P SVDWREKG VT VK Sbjct: 2 MNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRSVDWREKGYVTPVK 55 Query: 132 YQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQY 191 QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+GCNGG M AFQY Sbjct: 56 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNEGCNGGLMDYAFQY 114 Query: 192 IIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251 + DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV Sbjct: 115 VQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVA 173 Query: 252 VDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFGE 306 +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +YWLVKNSWG +G Sbjct: 174 IDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGM 233 Query: 307 EGYIRMARNKGNHCGIASFPSYPEI 331 GY++MA+++ NHCGIAS SYP + Sbjct: 234 GGYVKMAKDRRNHCGIASAASYPTV 258 >2O6X-A nrPDB Length = 310 Score = 271 bits (692), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 139/310 (44%), Positives = 189/310 (60%), Gaps = 8/310 (2%) Query: 25 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMT 84 D WH WK+ Y K+Y +++ RR IWEKN+K + HNL H +G+ +Y LG+N DMT Sbjct: 2 DDLWHQWKRMYNKEYNGADDQH-RRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 85 SEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAF 142 EE + L R + Y++N NR +PD +DWRE G VTEVK QG+CG+ WAF Sbjct: 61 FEEFKAKYLTEMSRASDILSHGVPYEAN-NRAVPDKIDWRESGYVTEVKDQGNCGSGWAF 119 Query: 143 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 202 S G +E Q +S S Q LVDCS +GN GC GG M A+QY+ G+++++ Sbjct: 120 STTGTMEGQYMKNERTSISFSEQQLVDCS-RPWGNNGCGGGLMENAYQYL-KQFGLETES 177 Query: 203 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 262 SYPY A++ +C+Y+ + A + + + G E LK V +GP +V VD F +Y Sbjct: 178 SYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDV-ESDFMMY 236 Query: 263 RSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCG 321 RSG+Y +C+ VNH VL VGYG G +YW+VKNSWG ++GE GYIRM RN+GN CG Sbjct: 237 RSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCG 296 Query: 322 IASFPSYPEI 331 IAS S P + Sbjct: 297 IASLASLPMV 306 >3QT4-A nrPDB Length = 329 Score = 259 bits (663), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 141/320 (44%), Positives = 195/320 (60%), Gaps = 25/320 (7%) Query: 24 LDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDM 83 W +K T+ K Y EE R+LI++ N+ + HN + G +Y MN GDM Sbjct: 23 FQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDM 82 Query: 84 TSEEVMSLMS-----------SLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKY 132 + EE ++ ++ +LR+P Y S+ + L SVDWR V+EVK Sbjct: 83 SKEEFLAYVNRGKAQKPKHPENLRMP--------YVSS-KKPLAASVDWRSN-AVSEVKD 132 Query: 133 QGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYI 192 QG CG+ W+FS GA+E QL L+ G+L SLS QNL+DCS+ YGN GC+GG+M +AF YI Sbjct: 133 QGQCGSSWSFSTTGAVEGQLALQRGRLTSLSEQNLIDCSS-SYGNAGCDGGWMDSAFSYI 191 Query: 193 IDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGV 252 D GI S+++YPY+A C++DS T S Y +LP G E+ L +AV GPV+V + Sbjct: 192 HD-YGIMSESAYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAI 250 Query: 253 DARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 DA F Y G++Y+ +C Q ++NHGVLVVGYG NG++YW++KNSWG +GE GY R Sbjct: 251 DATDELQF-YSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWR 309 Query: 312 MARNKGNHCGIASFPSYPEI 331 RN GN+CGIA+ SYP + Sbjct: 310 QVRNYGNNCGIATAASYPAL 329 >6BKI-A nrPDB Length = 215 Score = 259 bits (662), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 123/218 (56%), Positives = 157/218 (72%), Gaps = 4/218 (1%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +PDS+D+R+KG VT VK QG CG+CWAFS+ GALE QLK KTGKL++LS QNLVDC TE Sbjct: 1 VPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTEN 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 YG C GG+MTTAFQY+ N GIDS+ +YPY D+ C Y++ +AA C Y E+P G Sbjct: 61 YG---CGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGN 117 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEY 293 E LK AVA GP+SV +DA SF Y GVYY+ +C + NVNH VLVVGYG G ++ Sbjct: 118 EKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKH 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 W++KNSWG ++G +GY +ARNK N CGI + S+P++ Sbjct: 178 WIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >3QJ3-A nrPDB Length = 331 Score = 259 bits (662), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 139/314 (44%), Positives = 186/314 (59%), Gaps = 14/314 (4%) Query: 28 WHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEE 87 W +K TY + Y EE R+ I++K L+ HN ++ G+ SY LG+N DMT EE Sbjct: 22 WENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNLFTDMTPEE 81 Query: 88 VMSLMSSLRVPSQWQRN-ITYKS------NPNRILPDSVDWREKGCVTEVKYQGSCGACW 140 + + L +P+ +N I K+ N + P S DWR++G V+ VK QGSCG+ W Sbjct: 82 MKAYTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMVSPVKNQGSCGSSW 141 Query: 141 AFSAVGALEAQLKLKTGKLV--SLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGI 198 AFS+ GA+E+Q+K+ G S+S Q LVDC G C+GG+M AF Y+ N GI Sbjct: 142 AFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVPNALG---CSGGWMNDAFTYVAQNGGI 198 Query: 199 DSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPS 258 DS+ +YPY+ D C YD AA S Y L E++L + VA KGPV+V DA P Sbjct: 199 DSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPVAVAFDADDP- 257 Query: 259 FFLYRSGVYYEPSCTQN-VNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKG 317 F Y GVYY P+C N H VL+VGYG+ NG++YWLVKNSWG +G +GY ++ARN Sbjct: 258 FGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLDGYFKIARNAN 317 Query: 318 NHCGIASFPSYPEI 331 NHCGIA S P + Sbjct: 318 NHCGIAGVASVPTL 331 >3OF9-A nrPDB Length = 221 Score = 257 bits (657), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 123/221 (55%), Positives = 163/221 (73%), Gaps = 7/221 (3%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 3 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 120 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNG 290 L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + Sbjct: 121 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 180 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 181 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >5JA7-A nrPDB Length = 223 Score = 256 bits (655), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 125/217 (57%), Positives = 156/217 (71%), Gaps = 4/217 (1%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 PDSVD+R+KG VT VK QG CG+ WAFS+VGALE QLK KTGKL++LS QNLVDC +E Sbjct: 10 PDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE-- 67 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 N GC GG+MT AFQY+ N+GIDS+ +YPY ++ C Y+ +AA C Y E+P G E Sbjct: 68 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 126 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYW 294 LK AVA GPVSV +DA SF Y GVYY+ SC + N+NH VL VGYG G ++W Sbjct: 127 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 186 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 ++KNSWG N+G +GYI MARNK N CGIA+ S+P++ Sbjct: 187 IIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >3KFQ-A nrPDB Length = 221 Score = 256 bits (654), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 125/222 (56%), Positives = 163/222 (73%), Gaps = 6/222 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP SVDWR+KG VT VK Q CG+CWAFSA GALE Q+ KTGKLVSLS QNLVDCS + Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 GN+GCNGGFM AFQY+ +N G+DS+ SYPY A+D+ C+Y + A + +T + G+ Sbjct: 61 -GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGK 119 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLN 289 E L +AVA GP+SV +DA H SF Y+SG+Y+EP C ++N++HGVLVVGYG + + Sbjct: 120 EKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSD 179 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 +YWLVKNSWG +G GY+++A++K NHCGIA+ SYP + Sbjct: 180 NSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >2VHS-A nrPDB Length = 217 Score = 241 bits (614), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 119/218 (54%), Positives = 157/218 (72%), Gaps = 4/218 (1%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CGA +AFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 2 PRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 60 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + ++P +E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY-EPSCTQNVNHGVLVVGYGDL-NGKEY 293 L +AVA GP+SV +DA H SF Y+ G+Y+ + ++NH +LVVGYG + N ++Y Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 WLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >1CQD-A nrPDB Length = 221 Score = 216 bits (549), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 110/218 (50%), Positives = 139/218 (63%), Gaps = 8/218 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LPDS+DWRE G V VK QG CG+CWAFS V A+E ++ TG L+SLS Q LVDC+T Sbjct: 3 LPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTT-- 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG+M AFQ+I++N GI+S+ +YPY+ D C + Y +P Sbjct: 61 -ANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHN 119 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E L++AVAN+ PVSV +DA F LYRSG+ + SC + NH + VVGYG N K++W Sbjct: 120 EQSLQKAVANQ-PVSVTMDAAGRDFQLYRSGI-FTGSCNISANHALTVVGYGTENDKDFW 177 Query: 295 LVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYP 329 +VKNSWG N+GE GYIR RN N CGI F SYP Sbjct: 178 IVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYP 215 >1IWD-A nrPDB Length = 215 Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 107/218 (49%), Positives = 140/218 (64%), Gaps = 9/218 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR KG V +K Q CG+CWAFSAV A+E+ K++TG+L+SLS Q LVDC T Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTAS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 + GCNGG+M AFQYII N GID+ +YPY A+ C+ + R + + + + Sbjct: 61 H---GCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCK-PYRLRVVSINGFQRVTRNN 116 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E L+ AVA++ PVSV V+A F Y SG++ P C NHGV++VGYG +GK YW Sbjct: 117 ESALQSAVASQ-PVSVTVEAAGAPFQHYSSGIFTGP-CGTAQNHGVVIVGYGTQSGKNYW 174 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 +V+NSWG N+G +GYI M RN + CGIA PSYP Sbjct: 175 IVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYP 212 >1ICF-A nrPDB Length = 175 Score = 209 bits (531), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 99/172 (57%), Positives = 129/172 (75%), Gaps = 3/172 (1%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 2 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 60 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG 286 L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYG 171 >3P5W-A nrPDB Length = 220 Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 105/218 (48%), Positives = 141/218 (64%), Gaps = 6/218 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LPD VDWR G V ++K QG CG+CWAFS + A+E K+ TG L+SLS Q LVDC + Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 +GC+GGFMT FQ+II+N GI+++A+YPY A + +C D + + + Y +PY Sbjct: 61 -NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L+ AVA + PVSV ++A +F Y SG++ P C V+H V +VGYG G +Y Sbjct: 120 NEWALQTAVAYQ-PVSVALEAAGYNFQHYSSGIFTGP-CGTAVDHAVTIVGYGTEGGIDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG--NHCGIASFPSYP 329 W+VKNSWG +GEEGY+R+ RN G CGIA SYP Sbjct: 178 WIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYP 215 >1AEC-A nrPDB Length = 218 Score = 204 bits (520), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 102/218 (46%), Positives = 137/218 (62%), Gaps = 6/218 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR G V ++K QG CG CWAFSA+ +E K+ TG L+SLS Q L+DC + Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 +GCNGG++T FQ+II+N GI+++ +YPY A D +C D + T Y +PY Sbjct: 61 -NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L+ AV + PVSV +DA +F Y SG++ P C ++H V +VGYG G +Y Sbjct: 120 NEWALQTAVTYQ-PVSVALDAAGDAFKQYSSGIFTGP-CGTAIDHAVTIVGYGTEGGIDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH--CGIASFPSYP 329 W+VKNSW +GEEGY+R+ RN G CGIA+ PSYP Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >2ACT-A nrPDB Length = 220 Score = 201 bits (510), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 101/220 (45%), Positives = 138/220 (62%), Gaps = 10/220 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR G V ++K QG CG CWAFSA+ +E K+ +G L+SLS Q L+DC + Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQY---DSKYRAATCSKYTELP 231 +GC+GG++T FQ+II++ GI+++ +YPY A D C D KY T Y +P Sbjct: 61 -NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKY--VTIDTYENVP 117 Query: 232 YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGK 291 Y E L+ AV + PVSV +DA +F Y SG++ P C V+H +++VGYG G Sbjct: 118 YNNEWALQTAVTYQ-PVSVALDAAGDAFKQYASGIFTGP-CGTAVDHAIVIVGYGTEGGV 175 Query: 292 EYWLVKNSWGHNFGEEGYIRMARNKGNH--CGIASFPSYP 329 +YW+VKNSW +GEEGY+R+ RN G CGIA+ PSYP Sbjct: 176 DYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >2PNS-A nrPDB Length = 208 Score = 200 bits (508), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 105/216 (48%), Positives = 141/216 (65%), Gaps = 12/216 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ +DWR+KG VT VK QG CG+CWAFS V +E+ +++TG L+SLS Q LVDC+ + Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKK- 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG A+QYIIDN GID++A+YPYKA+ C+ K Y +P+ Sbjct: 60 --NHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCN 115 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E+ LK+AVA++ P V +DA F Y+SG++ P C +NHGV++VGY K+YW Sbjct: 116 ENALKKAVASQ-PSVVAIDASSKQFQHYKSGIFSGP-CGTKLNHGVVIVGY----WKDYW 169 Query: 295 LVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYP 329 +V+NSWG +GE+GYIRM R G CGIA P YP Sbjct: 170 IVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYP 205 >4YYR-A nrPDB Length = 222 Score = 199 bits (505), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 105/219 (47%), Positives = 140/219 (63%), Gaps = 7/219 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR +G V ++ QG CG+CWAFS V +E K+ T +L SLS Q LVDC+T Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATS- 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 Y N GC+GG+MT A+ YII N GI S ++YPY A +C D + AT Y +P Sbjct: 60 YKNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E+ LK AVAN+ PVSV ++A +F LY+SGV+ SC ++H V+ +GYG N +Y Sbjct: 120 NENALKNAVANQ-PVSVTIEAGGRAFELYKSGVFVG-SCGTKLDHAVVAIGYGSENDVDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYP 329 WLV+NSWG N+GE GYI++ RN CGIA +YP Sbjct: 178 WLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYP 216 >1S4V-A nrPDB Length = 229 Score = 199 bits (505), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 108/220 (49%), Positives = 142/220 (64%), Gaps = 9/220 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P SVDWR+KG VT VK QG CG+CWAFS + A+E ++KT KLVSLS Q LVDC T++ Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSK-YRAATCSKYTELPYG 233 N+GCNGG M AF++I GI ++A+YPY+A D C + A + + +P Sbjct: 62 --NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG-DLNGKE 292 E+ L +AVAN+ PVSV +DA F Y GV + SC ++HGV +VGYG ++G + Sbjct: 120 DENALLKAVANQ-PVSVAIDAGGSDFQFYSEGV-FTGSCGTELDHGVAIVGYGTTIDGTK 177 Query: 293 YWLVKNSWGHNFGEEGYIRMAR---NKGNHCGIASFPSYP 329 YW VKNSWG +GE+GYIRM R +K CGIA SYP Sbjct: 178 YWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYP 217 >1O0E-A nrPDB Length = 208 Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 106/216 (49%), Positives = 137/216 (63%), Gaps = 12/216 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ +DWR+KG VT VK QGSCG+CWAFS V +E+ +++TG L+SLS Q LVDC + Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDKK- 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG A+QYII+N GID+ A+YPYKA+ CQ SK + Y +P+ Sbjct: 60 --NHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCN 115 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E LK+AVA + P +V +DA F Y SG++ P C +NHGV +VGY YW Sbjct: 116 EXALKQAVAVQ-PSTVAIDASSAQFQQYSSGIFSGP-CGTKLNHGVTIVGY----QANYW 169 Query: 295 LVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYP 329 +V+NSWG +GE+GYIRM R G CGIA P YP Sbjct: 170 IVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYP 205 >6CZS-A nrPDB Length = 335 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 122/330 (36%), Positives = 174/330 (52%), Gaps = 19/330 (5%) Query: 7 VLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLHNLE 65 +L V A+L + H+ W + K Y EE RL + N + + HN Sbjct: 14 LLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYS--TEEYHHRLQTFASNWRKINAHN-- 69 Query: 66 HSMGMHSYDLGMNHLGDMTSEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWRE 123 G H++ + +N DM+ E+ L S + S + N + P P SVDWR+ Sbjct: 70 --NGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRK 124 Query: 124 KG-CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNG 182 KG V+ VK QG+CG+ W FS GALE+ + + TGK++SL+ Q LVDC+ + + N GC G Sbjct: 125 KGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHGCQG 183 Query: 183 GFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAV 242 G + AF+YI+ NKGI + +YPY+ D C++ + E+ + EAV Sbjct: 184 GLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAV 243 Query: 243 ANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN---VNHGVLVVGYGDLNGKEYWLVKNS 299 A PVS + F +YR+G+Y SC + VNH VL VGYG+ NG YW+VKNS Sbjct: 244 ALYNPVSFAFEVTQ-DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302 Query: 300 WGHNFGEEGYIRMARNKGNHCGIASFPSYP 329 WG +G GY + R K N CG+A+ SYP Sbjct: 303 WGPQWGMNGYFLIERGK-NMCGLAACASYP 331 >3F75-A nrPDB Length = 224 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 103/219 (47%), Positives = 142/219 (64%), Gaps = 10/219 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR +GCVT VK Q CG+CWAFS GALE KTGKLVSLS Q L+DCS + Sbjct: 7 LPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRAE 66 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 GN+ C+GG M AFQY++D+ GI S+ +YPY A D++C+ S + + ++P Sbjct: 67 -GNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRS 125 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG--DLNGKE 292 E +K A+A K PVS+ ++A F Y GV ++ SC +++HGVL+VGYG + K+ Sbjct: 126 EAAMKAALA-KSPVSIAIEADQMPFQFYHEGV-FDASCGTDLDHGVLLVGYGTDKESKKD 183 Query: 293 YWLVKNSWGHNFGEEGYIRMARNKG--NHCGI---ASFP 326 +W++KNSWG +G +GY+ MA +KG CG+ ASFP Sbjct: 184 FWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFP 222 >3BCN-A nrPDB Length = 209 Score = 192 bits (489), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 104/217 (47%), Positives = 137/217 (63%), Gaps = 14/217 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ VDWR KG V +K QG CG+CWAFS V +E+ +++TG L+SLS Q LVDCS + Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKK- 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSK-YRAATCSKYTELPYG 233 N GC GG+ A+QYII N GID++A+YPYKA C+ K R C +P Sbjct: 60 --NHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKKVVRIDGCKG---VPQC 114 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E+ LK AVA++ P V +DA F Y+ G++ P C +NHGV++VGY GK+Y Sbjct: 115 NENALKNAVASQ-PSVVAIDASSKQFQHYKGGIFTGP-CGTKLNHGVVIVGY----GKDY 168 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYP 329 W+V+NSWG ++GE+GY RM R G CGIA P YP Sbjct: 169 WIVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYP 205 >2FO5-A nrPDB Length = 262 Score = 191 bits (486), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 108/226 (47%), Positives = 139/226 (61%), Gaps = 18/226 (7%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP SVDWR+KG VT VK QG CG+CWAFS V ++E ++TG LVSLS Q L+DC T Sbjct: 4 LPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTAD 63 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSK-------Y 227 N GC GG M AF+YI +N G+ ++A+YPY+A C RAA S + Sbjct: 64 --NDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNV---ARAAQNSPVVVHIDGH 118 Query: 228 TELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGD 287 ++P E+ L AVAN+ PVSV V+A +F Y GV+ C ++HGV VVGYG Sbjct: 119 QDVPANSEEDLARAVANQ-PVSVAVEASGKAFMFYSEGVFTG-ECGTELDHGVAVVGYGV 176 Query: 288 L-NGKEYWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 +GK YW VKNSWG ++GE+GYIR+ ++ G CGIA SYP Sbjct: 177 AEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYP 222 >4YYQ-A nrPDB Length = 217 Score = 189 bits (480), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 103/218 (47%), Positives = 145/218 (66%), Gaps = 7/218 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR KG V ++ QG CG+CWAFSAV A+E+ K+ TG+L+SLS Q L+DC+ + Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCA-QS 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 Y N GC GG++ AF+YII N+GI S ++YPY +C+ AT Y +P Sbjct: 60 YKNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCR-TGLASIATIDSYQYVPSNN 118 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E+ LK AVAN+ PVSV V+A +F LY+SGV + SC ++H V+++GYG NG +YW Sbjct: 119 ENALKNAVANQ-PVSVAVEAAGRAFQLYKSGV-FTGSCGVAIDHAVVLIGYGKYNGVDYW 176 Query: 295 LVKNSWGHNFGEEGYIRMARN---KGNHCGIASFPSYP 329 L++NSWG N+GE+GY+++ RN CG+A YP Sbjct: 177 LLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYP 214 >1NB3-A nrPDB Length = 220 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 99/218 (45%), Positives = 132/218 (60%), Gaps = 7/218 (3%) Query: 116 PDSVDWREKG-CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 P S+DWR+KG V+ VK QGSCG+CW FS GALE+ + + TGK++SL+ Q LVDC+ + Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCA-QN 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 + N GC GG + AF+YI NKGI + +YPYK D C++ A + Sbjct: 61 FNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMND 120 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN---VNHGVLVVGYGDLNGK 291 E+ + EAVA PVS + + F +YR G+Y SC + VNH VL VGYG+ NG Sbjct: 121 EEAMVEAVALYNPVSFAFEVTN-DFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGI 179 Query: 292 EYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYP 329 YW+VKNSWG +G GY + R K N CG+A+ SYP Sbjct: 180 PYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYP 216 >5A24-A nrPDB Length = 222 Score = 187 bits (475), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 108/223 (48%), Positives = 140/223 (62%), Gaps = 11/223 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P +VDWR G VT VK Q CG CWAFSAV A+E ++KTG L SLS + +VDC T Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNG 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA---MDQKCQYDSKYRAATCSKYTELP 231 +KGCNGG AFQY+++N+GID+++ YPY A C S AA+ + Y ++P Sbjct: 61 -NDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVP 119 Query: 232 YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG-DLN- 289 E L++A A + P+SV +DA PSF Y SG+Y P C N++H V VVGYG D N Sbjct: 120 ANNEQALQQAAATQ-PISVAIDASDPSFQSYSSGIYSGP-CNTNLDHAVTVVGYGTDPNS 177 Query: 290 GKEYWLVKNSWGHNFGEEGYI--RMARNKG-NHCGIASFPSYP 329 G YW+VKNSWG ++G+EGYI +M N CGIA SYP Sbjct: 178 GNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYP 220 >4YYW-A nrPDB Length = 220 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 99/219 (45%), Positives = 134/219 (61%), Gaps = 7/219 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR KG V ++ QG CG+CW FS +E +K+ T L SLS Q L+DC+ Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCA-PS 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYR-AATCSKYTELPYG 233 Y + GC GG+M A+ YII ++GI S++ YPY A C AT S Y ++P Sbjct: 60 YKDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPAD 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 ED LK+AVAN+ PVSV +DA + Y SGV+ SC +H V+VVGYG +G Y Sbjct: 120 NEDALKKAVANQ-PVSVAIDASSAAVKEYSSGVFVG-SCGVANDHAVVVVGYGTESGVNY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYP 329 WLV+NSWG +GEEGY+++ R+ + CGIA +YP Sbjct: 178 WLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYP 216 >6MIS-A nrPDB Length = 215 Score = 182 bits (463), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 93/221 (42%), Positives = 142/221 (64%), Gaps = 11/221 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P S+DWR+ G VT VK QG CG+CWAF+++ +E+ K+K G LVSLS Q ++DC+ Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAV-- 58 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 + GC GG++ A+ +II NKG+ S A YPYKA C+ + +A ++YT + Sbjct: 59 --SYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNN 116 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG-DLNGKEY 293 E + AV+N+ P++ +DA +F Y+ GV+ P C +NH ++++GYG D +GK++ Sbjct: 117 ERNMMYAVSNQ-PIAAALDASG-NFQHYKRGVFTGP-CGTRLNHAIVIIGYGQDSSGKKF 173 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPEI 331 W+V+NSWG +GE GYIR+AR+ + CGIA P YP + Sbjct: 174 WIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >5EF4-A nrPDB Length = 385 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 107/273 (39%), Positives = 148/273 (54%), Gaps = 22/273 (8%) Query: 73 YDLGMNHLGDMTSEEVMSLMSSLRVPSQWQR-----NITYKSNPNR--------ILPDSV 119 Y L +N DMT+ E ++ ++ ++ S +Q + ++PN+ +PD V Sbjct: 76 YKLKVNEFADMTNLEFVNTYANSKI-SHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKV 134 Query: 120 DWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKG 179 DWREK VT+VK QG CG+CWAF+AV ALE ++TGKLV S Q LVDC N G Sbjct: 135 DWREKNAVTDVKGQGGCGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCDMT---NAG 191 Query: 180 CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLK 239 C+GG M AF Y+I + GI +ASYPY + C +P E+ L+ Sbjct: 192 CDGGLMEPAFTYVIKHGGIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALR 251 Query: 240 EAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGD-LNGKEYWLVKN 298 +AVA++ PV+ G+ Y GVY C NHGV +VGYG+ G ++W VKN Sbjct: 252 KAVAHQ-PVATGIQLSGHGLQFYSEGVYTG-DCGTEPNHGVGIVGYGENEKGIKFWTVKN 309 Query: 299 SWGHNFGEEGYIRMARN--KGNHCGIASFPSYP 329 SWG +GE+GYI + R K CG+A S+P Sbjct: 310 SWGPTWGEKGYIHLQRGARKEGLCGVAMHSSFP 342 >4QRX-A nrPDB Length = 363 Score = 176 bits (447), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 114/307 (37%), Positives = 169/307 (55%), Gaps = 23/307 (7%) Query: 31 WKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMS 90 W + K YK +E+ R I++ NLK++ N ++ +SY LG+N DM+++E Sbjct: 69 WMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKN----NSYWLGLNVFADMSNDEFKE 124 Query: 91 LMSSLRVPSQWQRNITYK---SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGA 147 + + ++Y+ ++ + +P+ VDWR+KG VT VK QGSCG+ WAFSAV Sbjct: 125 KYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVST 184 Query: 148 LEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYK 207 +E+ +K++TG L S Q L+DC Y GCNGG+ +A Q ++ GI +YPY+ Sbjct: 185 IESIIKIRTGNLNEYSEQELLDCDRRSY---GCNGGYPWSALQ-LVAQYGIHYRNTYPYE 240 Query: 208 AMDQKCQYDSK--YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSG 265 + + C+ K Y A T PY E L ++AN+ PVSV ++A F LYR G Sbjct: 241 GVQRYCRSREKGPYAAKTDGVRQVQPY-NEGALLYSIANQ-PVSVVLEAAGKDFQLYRGG 298 Query: 266 VYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH---CGI 322 ++ P C V+H V VGY G Y L++NSWG +GE GYIR+ R GN CG+ Sbjct: 299 IFVGP-CGNKVDHAVAAVGY----GPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGL 353 Query: 323 ASFPSYP 329 + YP Sbjct: 354 YTSSFYP 360 >2BDZ-A nrPDB Length = 214 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 96/218 (44%), Positives = 132/218 (60%), Gaps = 14/218 (6%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P+S+DWREKG VT VK Q CG+CWAFS V +E K+ TG+L+SLS Q L+DC + Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCERRSH 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQY-DSKYRAATCSKYTELPYGR 234 GC+GG+ TT+ QY++DN G+ ++ YPY+ +C+ D K + Y +P Sbjct: 62 ---GCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPAND 117 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E L +A+AN+ PVSV D+R F Y+ G+Y P C N +H V VGY GK Y Sbjct: 118 EISLIQAIANQ-PVSVVTDSRGRGFQFYKGGIYEGP-CGTNTDHAVTAVGY----GKTYL 171 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 L+KNSWG N+GE+GYIR+ R G CG+ + +P Sbjct: 172 LLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFP 209 >1YAL-A nrPDB Length = 218 Score = 174 bits (441), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 96/218 (44%), Positives = 129/218 (59%), Gaps = 10/218 (4%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P S+DWR KG VT VK QG+CG+CWAFS + +E K+ TG L+ LS Q LVDC Y Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDKHSY 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ-YDSKYRAATCSKYTELPYGR 234 GC GG+ TT+ QY+ +N G+ + YPY+A KC+ D + Y +P Sbjct: 62 ---GCKGGYQTTSLQYVANN-GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNC 117 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E A+AN+ P+SV V+A F LY+SGV+ P C ++H V VGYG +GK Y Sbjct: 118 ETSFLGALANQ-PLSVLVEAGGKPFQLYKSGVFDGP-CGTKLDHAVTAVGYGTSDGKNYI 175 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 ++KNSWG N+GE+GY+R+ R GN CG+ YP Sbjct: 176 IIKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >2B1M-A nrPDB Length = 246 Score = 174 bits (441), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 97/228 (42%), Positives = 136/228 (59%), Gaps = 18/228 (7%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P+S DW +KG +T+VK+QG CG+ WAFSA GA+EA + TG LVSLS Q L+DC E Sbjct: 3 PESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDE-- 60 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKY-------T 228 ++GC G+ +F++++ + GI S+A YPYKA D KC+ + T Y Sbjct: 61 -SEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNE 119 Query: 229 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ--NVNHGVLVVGYG 286 E L+ V + P+SV +DA+ F Y G+Y +C+ +NH VL+VGYG Sbjct: 120 STESEAESSLQSFVLEQ-PISVSIDAK--DFHFYSGGIYDGGNCSSPYGINHFVLIVGYG 176 Query: 287 DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPEI 331 +G +YW+ KNSWG ++G +GYIR+ RN GN CG+ F SYP I Sbjct: 177 SEDGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPII 224 >3U8E-A nrPDB Length = 222 Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 100/223 (44%), Positives = 131/223 (58%), Gaps = 16/223 (7%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P S+DWR+KG VT VK QG+CG CWAF A GA+E + TG+L+S+S Q +VDC T Sbjct: 2 PASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXXX 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GG AF+++I N GI SDA+YPY +D C + K AA YT +P Sbjct: 62 XXX---GGDADDAFRWVITNGGIASDANYPYTGVDGTCDLN-KPIAARIDGYTNVP-NSS 116 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRS-GVYYEPSCTQN---VNHGVLVVGYGDLNGK 291 L +AVA K PVSV + SF LY G++ SC+ + V+H VL+VGYG NG Sbjct: 117 SALLDAVA-KQPVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGS-NGT 174 Query: 292 --EYWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 +YW+VKNSWG +G +GYI + RN C I ++ SYP Sbjct: 175 NADYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYP 217 >6EXO-A nrPDB Length = 215 Score = 166 bits (420), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 15/211 (7%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P +VDWREKG VT VK QG CG+CWAFS +G +E Q ++ LVSLS Q LV C T + Sbjct: 2 PAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDF 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKG--IDSDASYPYKAMD---QKCQYDSKYRAATCSKYTEL 230 GC GG M AF +I+++ G + ++ASYPY + + +CQ + A + + +L Sbjct: 62 ---GCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDL 118 Query: 231 PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYGDLN 289 P ED + +A GP+++ VDA SF Y G+ SCT + ++HGVL+VGY D + Sbjct: 119 PQ-DEDAIAAYLAENGPLAIAVDAT--SFMDYNGGILT--SCTSEQLDHGVLLVGYNDAS 173 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHC 320 YW++KNSW + +GE+GYIR+ + N C Sbjct: 174 NPPYWIIKNSWSNMWGEDGYIRIEKGT-NQC 203 >1PCI-A nrPDB Length = 322 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 119/317 (37%), Positives = 173/317 (54%), Gaps = 26/317 (8%) Query: 24 LDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDM 83 L ++ W + K Y+ +E+ R I++ NL ++ N ++ +SY LG+N D+ Sbjct: 18 LIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKN----NSYWLGLNEFADL 73 Query: 84 TSEE-----VMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGA 138 +++E V SL+ + + + + N LP++VDWR+KG VT V++QGSCG+ Sbjct: 74 SNDEFNEKYVGSLIDAT-IEQSYDEEFINEDIVN--LPENVDWRKKGAVTPVRHQGSCGS 130 Query: 139 CWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGI 198 CWAFSAV +E K++TGKLV LS Q LVDC + GC GG+ A +Y+ N GI Sbjct: 131 CWAFSAVATVEGINKIRTGKLVELSEQELVDCERRSH---GCKGGYPPYALEYVAKN-GI 186 Query: 199 DSDASYPYKAMDQKCQYDSKYRAATCSKYT---ELPYGREDVLKEAVANKGPVSVGVDAR 255 + YPYKA C+ +K K + + E L A+A K PVSV V+++ Sbjct: 187 HLRSKYPYKAKQGTCR--AKQVGGPIVKTSGVGRVQPNNEGNLLNAIA-KQPVSVVVESK 243 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 F LY+ G++ P C V+ V VGYG GK Y L+KNSWG +GE+GYIR+ R Sbjct: 244 GRPFQLYKGGIFEGP-CGTKVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRA 302 Query: 316 KGNH---CGIASFPSYP 329 GN CG+ YP Sbjct: 303 PGNSPGVCGLYKSSYYP 319 >2CIO-A nrPDB Length = 212 Score = 159 bits (402), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 96/220 (43%), Positives = 127/220 (57%), Gaps = 16/220 (7%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P+ VDWR+KG VT VK QGSCG+CWAFSAV +E +K++TG L S Q L+DC Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSK--YRAATCSKYTELPY 232 Y GCNGG+ +A Q ++ GI +YPY+ + + C+ K Y A T PY Sbjct: 61 Y---GCNGGYPWSALQ-LVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPY 116 Query: 233 GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKE 292 E L ++AN+ PVSV ++A F LYR G++ P C V+H V VGY G Sbjct: 117 -NEGALLYSIANQ-PVSVVLEAAGKDFQLYRGGIFVGP-CGNKVDHAVAAVGY----GPN 169 Query: 293 YWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 Y L+KNSWG +GE GYIR+ R GN CG+ + YP Sbjct: 170 YILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYP 209 >4PI3-A nrPDB Length = 216 Score = 153 bits (387), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 89/211 (42%), Positives = 122/211 (57%), Gaps = 15/211 (7%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P +VDWR +G VT VK QG CG+CWAFSA+G +E Q L L +LS Q LV C Sbjct: 3 PAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKT-- 60 Query: 176 GNKGCNGGFMTTAFQYII--DNKGIDSDASYPY---KAMDQKCQYDSKYRAATCSKYTEL 230 + GC+GG M AF++I+ +N + ++ SYPY + + C AT + + EL Sbjct: 61 -DSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL 119 Query: 231 PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLN 289 P E + +A GPV+V VDA S+ Y GV SC ++ ++HGVL+VGY D Sbjct: 120 PQ-DEAQIAAWLAVNGPVAVAVDAS--SWMTYTGGVM--TSCVSEQLDHGVLLVGYNDSA 174 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHC 320 YW++KNSW +GEEGYIR+A+ N C Sbjct: 175 AVPYWIIKNSWTTQWGEEGYIRIAKGS-NQC 204 >1PPO-A nrPDB Length = 216 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 98/216 (45%), Positives = 129/216 (59%), Gaps = 15/216 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR+KG VT V++QGSCG+CWAFSAV +E K++TGKLV LS Q LVDC Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 + GC GG+ A +Y+ N GI + YPYKA C+ +K K + + GR Sbjct: 61 H---GCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCR--AKQVGGPIVKTSGV--GR 112 Query: 235 -----EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLN 289 E L A+A K PVSV V+++ F LY+ G++ P C V+H V VGYG Sbjct: 113 VQPNNEGNLLNAIA-KQPVSVVVESKGRPFQLYKGGIFEGP-CGTKVDHAVTAVGYGKSG 170 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF 325 GK Y L+KNSWG +GE+GYIR+ R GN G+ Sbjct: 171 GKGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGL 206 >1GEC-E nrPDB Length = 216 Score = 150 bits (379), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 98/219 (44%), Positives = 125/219 (57%), Gaps = 10/219 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+SVDWR KG VT VK+QG C +CWAFS V +E K+KTG LV LS Q LVDC + Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCDLQS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYG 233 Y GCN G+ +T+ QY+ N GI A YPY A Q C+ + + + Sbjct: 61 Y---GCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L A+A++ PVSV V++ F Y+ G+ +E SC V+H V VGYG GK Y Sbjct: 117 NEGSLLNAIAHQ-PVSVVVESAGRDFQNYKGGI-FEGSCGTKVDHAVTAVGYGKSGGKGY 174 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 L+KNSWG +GE GYIR+ R GN CG+ YP Sbjct: 175 ILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYP 213 >3IOQ-A nrPDB Length = 213 Score = 146 bits (369), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 90/219 (41%), Positives = 128/219 (58%), Gaps = 14/219 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P S+DWR+KG VT V+ QG CG+CW FS+V A+E K+ TG+L+SLS Q L+DC Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCERRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 Y GC GGF A QY+ N GI YPY+ + ++C+ +K +P Sbjct: 61 Y---GCRGGFPLYALQYVA-NSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L + +A + PVS+ V+A+ +F YR G++ P C +++H V VGYG+ +Y Sbjct: 117 NEQALIQRIAIQ-PVSIVVEAKGRAFQNYRGGIFAGP-CGTSIDHAVAAVGYGN----DY 170 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYP 329 L+KNSWG +GE GYIR+ R GN CG+ S +P Sbjct: 171 ILIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFP 209 >5I4H-A nrPDB Length = 106 Score = 142 bits (357), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 67/104 (64%), Positives = 81/104 (77%), Gaps = 1/104 (0%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 3 PRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKY 219 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKY 105 >3BPM-A nrPDB Length = 243 Score = 137 bits (346), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 85/237 (35%), Positives = 126/237 (53%), Gaps = 22/237 (9%) Query: 107 YKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQN 166 YK ++ + DWR G VT VK Q CG+CWAFS+VG++E+Q ++ L S Q Sbjct: 12 YKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQE 71 Query: 167 LVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA-MDQKCQYDSKYRAATCS 225 LVDCS + N GC GG++T AF +ID G+ S YPY + + + C T Sbjct: 72 LVDCSVK---NNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIK 128 Query: 226 KYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGY 285 Y +P +D KEA+ GP+S+ + A F YR G +Y+ C NH V++VGY Sbjct: 129 SYVSIP---DDKFKEALRYLGPISISI-AASDDFAFYRGG-FYDGECGAAPNHAVILVGY 183 Query: 286 G--DLNGKE--------YWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 G D+ ++ Y+++KNSWG ++GE GYI + ++ + C I + P Sbjct: 184 GMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVP 240 >3BPF-A nrPDB Length = 241 Score = 137 bits (345), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 82/226 (36%), Positives = 123/226 (54%), Gaps = 22/226 (9%) Query: 120 DWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKG 179 DWR VT VK Q +CG+CWAFS++G++E+Q ++ KL++LS Q LVDCS + Y G Sbjct: 23 DWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNY---G 79 Query: 180 CNGGFMTTAFQYIIDNKGIDSDASYPYKA-MDQKCQYDSKYRAATCSKYTELPYGREDVL 238 CNGG + AF+ +I+ GI D YPY + C D Y +P ++ L Sbjct: 80 CNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP---DNKL 136 Query: 239 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG------DLNGKE 292 KEA+ GP+S+ V A F Y+ G+ ++ C +NH V++VG+G L K Sbjct: 137 KEALRFLGPISISV-AVSDDFAFYKEGI-FDGECGDQLNHAVMLVGFGMKEIVNPLTKKG 194 Query: 293 ----YWLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYPEI 331 Y+++KNSWG +GE G+I + ++ CG+ + P I Sbjct: 195 EKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >5JT8-A nrPDB Length = 333 Score = 137 bits (345), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 96/315 (30%), Positives = 154/315 (48%), Gaps = 29/315 (9%) Query: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60 MK L+ L A+ + +KK +GK Y+ EEA R +++ LK+V Sbjct: 1 MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVE 60 Query: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKS---NPNRILPD 117 HN G+ + +N DM+ +E +S + + + K N LP Sbjct: 61 EHN-----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQ 115 Query: 118 SVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGN 177 + DWR+K +T ++ QGSCG+CWAF+A G E+ ++ + + LS Q LVDC+ +Y Sbjct: 116 NFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDP 175 Query: 178 ----KGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPY- 232 GC G+ T AF+Y+I G+ + +YPY Q C D + + S Y +L Y Sbjct: 176 SYQCNGCGSGYSTEAFKYMI-RTGLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYH 234 Query: 233 -GREDVLKEAVANKGPVSVGVDARHPSFFLYRS-------GVYYEPSCTQNVNHGVLVVG 284 EDV+ + GPV + + H S +R+ GV Y + T +H V++VG Sbjct: 235 SSDEDVMY-TIQQHGPVVIYM---HGSNNYFRNLGNGVLRGVAYNDAYT---DHAVILVG 287 Query: 285 YGDLNGKEYWLVKNS 299 +G + G +YW+++NS Sbjct: 288 WGTVQGVDYWIIRNS 302 >1M6D-A nrPDB Length = 214 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 79/213 (37%), Positives = 116/213 (54%), Gaps = 6/213 (2%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P DWR KG VT+VK QG CG+CWAFS G +E Q L G L+SLS Q L+DC Sbjct: 2 PPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKM-- 59 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 +K C GG + A+ I + G++++ Y Y+ Q CQ+ ++ EL E Sbjct: 60 -DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQ-NE 117 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYW 294 L +A +GP+SV ++A F+ + P C+ ++H VL+VGYG + +W Sbjct: 118 QKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFW 177 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327 +KNSWG ++GE+GY + R G CG+ + S Sbjct: 178 AIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMAS 209 >5I4H-B nrPDB Length = 112 Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 54/110 (49%), Positives = 79/110 (71%), Gaps = 6/110 (5%) Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGY 285 + ++P +E L +AVA GP+SV +DA H SF Y+ G+Y+EP C+ ++++HGVLVVGY Sbjct: 4 FVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGY 62 Query: 286 G----DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 G + + +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 63 GFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >1JQP-A nrPDB Length = 438 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 75/228 (32%), Positives = 116/228 (50%), Gaps = 22/228 (9%) Query: 115 LPDSVDWRE-KGC--VTEVKYQGSCGACWAFSAVGALEAQLKLKT--GKLVSLSAQNLVD 169 LP+S DWR +G V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 206 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 265 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSK----YRAATCS 225 CS +GC+GGF + G+ + +PY A D C+ Y + Sbjct: 266 CSPYA---QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 322 Query: 226 KYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHG 279 E ++K + GP++V + H F Y SG+Y+ + + NH Sbjct: 323 VGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHA 381 Query: 280 VLVVGYGD--LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF 325 VL+VGYG + G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 382 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESI 428 >3PDF-A nrPDB Length = 441 Score = 111 bits (277), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 76/229 (33%), Positives = 118/229 (51%), Gaps = 22/229 (9%) Query: 114 ILPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT--GKLVSLSAQNLV 168 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 206 FLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVV 265 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 228 CS +Y +GC GGF + G+ +A +PY D C+ S+Y Sbjct: 266 SCS--QYA-QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 322 Query: 229 ELP--YG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNH 278 + YG E ++K + + GP++V + + F Y+ G+Y+ + NH Sbjct: 323 YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNH 381 Query: 279 GVLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF 325 VL+VGYG +G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 382 AVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESI 429 >1XKG-A nrPDB Length = 312 Score = 110 bits (275), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 86/304 (28%), Positives = 147/304 (48%), Gaps = 28/304 (9%) Query: 22 PTLDHHWHLWKKTYGKQYKE-KNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHL 80 P+ + +KK + K Y ++EEA R+ E ++K+V S +NHL Sbjct: 2 PSSIKTFEEYKKAFNKSYATFEDEEAARKNFLE-SVKYV-----------QSNGGAINHL 49 Query: 81 GDMTSEE-----VMSLMSSLRVPSQWQRNI-TYKSNPNRILPDSVDWREKGCVTEVKYQG 134 D++ +E +MS + + +Q+ N T + N P +D R+ VT ++ QG Sbjct: 50 SDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQG 109 Query: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194 CG+ WAFS V A E+ + + L+ Q LVDC+++ GC+G + +YI Sbjct: 110 GCGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCASQ----HGCHGDTIPRGIEYIQH 165 Query: 195 NKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANK-GPVSVGVD 253 N G+ ++ Y Y A +Q C+ + R S Y ++ + ++EA+A ++V + Sbjct: 166 N-GVVQESYYRYVAREQSCRRPNAQRFG-ISNYCQIYPPNANKIREALAQTHSAIAVIIG 223 Query: 254 ARHPSFFLYRSG--VYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 + F + G + + Q H V +VGY + G +YW+V+NSW N+G+ GY Sbjct: 224 IKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGY 283 Query: 312 MARN 315 A N Sbjct: 284 FAAN 287 >3PBH-A nrPDB Length = 317 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%) Query: 115 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168 LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+ Sbjct: 64 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 123 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221 C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 124 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 181 Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255 T CSK E Y +D++ E N GPV G + Sbjct: 182 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 239 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 240 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 299 Query: 316 KGNHCGIAS 324 + +HCGI S Sbjct: 300 Q-DHCGIES 307 >5VCN-A nrPDB Length = 222 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 63/203 (31%), Positives = 104/203 (51%), Gaps = 9/203 (4%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P +D R+ VT ++ QG CG+CWAFS V A E+ + + L+ Q LVDC+++ Sbjct: 11 PAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQ-- 68 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GC+G + +YI N G+ ++ Y Y A +Q C+ + R S Y ++ Sbjct: 69 --HGCHGDTIPRGIEYIQHN-GVVQESYYRYVAREQSCRRPNAQRFGI-SNYCQIYPPNA 124 Query: 236 DVLKEAVANK-GPVSVGVDARHPSFFLYRSG--VYYEPSCTQNVNHGVLVVGYGDLNGKE 292 + ++EA+A ++V + + F + G + + Q H V +VGY + G + Sbjct: 125 NKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVD 184 Query: 293 YWLVKNSWGHNFGEEGYIRMARN 315 YW+V+NSW N+G+ GY A N Sbjct: 185 YWIVRNSWDTNWGDNGYGYFAAN 207 >5VPK-A nrPDB Length = 223 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 64/199 (32%), Positives = 101/199 (50%), Gaps = 11/199 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P +D R VT ++ QG CG+CWAFS V A E+ + LS Q LVDC+++ Sbjct: 11 VPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQ- 69 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 GC+G + +YI N G+ + SYPY A +Q+C+ + S Y ++ Sbjct: 70 ---HGCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQQCRRPNSQHYGI-SNYCQIYPPD 124 Query: 235 EDVLKEAVANKG---PVSVGV-DARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNG 290 ++EA+ V +G+ D R + R+ + ++ N H V +VGYG G Sbjct: 125 VKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNY-HAVNIVGYGSTQG 183 Query: 291 KEYWLVKNSWGHNFGEEGY 309 +YW+V+NSW +G+ GY Sbjct: 184 VDYWIVRNSWDTTWGDSGY 202 >3CBK-A nrPDB Length = 266 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 117/249 (46%), Gaps = 44/249 (17%) Query: 115 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168 LP S D RE+ + E++ QGSCG+ WAF AV A+ ++ + T VS+ SA++L+ Sbjct: 7 LPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 66 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221 C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 67 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEAHVNGARPP 124 Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255 T CSK E Y +D++ E N GPV G + Sbjct: 125 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 182 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 183 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 242 Query: 316 KGNHCGIAS 324 + +HCGI S Sbjct: 243 Q-DHCGIES 250 >1EF7-A nrPDB Length = 242 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 77/227 (33%), Positives = 109/227 (48%), Gaps = 42/227 (18%) Query: 115 LPDSVDWREKGCVTEVKYQGS---------CGACWAFSAVGALEAQLKLK-TGKLVS--L 162 LP S DWR V V Y CG+CWA ++ A+ ++ +K G S L Sbjct: 1 LPKSWDWRN---VDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 57 Query: 163 SAQNLVDCSTEKYGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRA 221 S QN++DC GN G C GG + + Y GI + Y+A DQ+C D + Sbjct: 58 SVQNVIDC-----GNAGSCEGGNDLSVWDYA-HQHGIPDETCNNYQAKDQEC--DKFNQC 109 Query: 222 ATCSKYTELPY----------------GREDVLKEAVANKGPVSVGVDARHPSFFLYRSG 265 TC+++ E GRE ++ E AN GP+S G+ A Y G Sbjct: 110 GTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATE-RLANYTGG 167 Query: 266 VYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 +Y E T +NH V V G+G +G EYW+V+NSWG +GE G++R+ Sbjct: 168 IYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 214 >1DEU-A nrPDB Length = 277 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 75/224 (33%), Positives = 108/224 (48%), Gaps = 36/224 (16%) Query: 115 LPDSVDWREKGCVTEVKYQGS------CGACWAFSAVGALEAQLKLK-TGKLVS--LSAQ 165 LP S DWR V + CG+CWA ++ A+ ++ +K G S LS Q Sbjct: 36 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 95 Query: 166 NLVDCSTEKYGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATC 224 N++DC GN G C GG + + Y GI + Y+A DQ+C D + TC Sbjct: 96 NVIDC-----GNAGSCEGGNDLSVWDYA-HQHGIPDETCNNYQAKDQEC--DKFNQCGTC 147 Query: 225 SKYTELPY----------------GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268 +++ E GRE ++ E AN GP+S G+ A Y G+Y Sbjct: 148 NEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATE-RLANYTGGIYA 205 Query: 269 EPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 E T +NH V V G+G +G EYW+V+NSWG +GE G++R+ Sbjct: 206 EYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 249 >1CPJ-A nrPDB Length = 260 Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 122/250 (48%), Gaps = 46/250 (18%) Query: 115 LPDSVDWREK--GC--VTEVKYQGSCGACWAFSAVGALEAQLKLKT-GKL-VSLSAQNLV 168 LP+S D RE+ C + +++ QGSCG+CWAF AV A+ ++ + T G++ V +SA++L+ Sbjct: 7 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 66 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PY--------------- 206 C + G+ GCNGG+ + A+ + KG+ S Y PY Sbjct: 67 TCCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPP 124 Query: 207 ---KAMDQKCQ------YDSKYRAATCSKYTELPYGREDVLKEAVAN---KGPVSVGVDA 254 + KC Y + Y+ YT Y D KE +A GPV G Sbjct: 125 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTS--YSVSDSEKEIMAEIYKNGPVE-GAFT 181 Query: 255 RHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 314 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 182 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILR 241 Query: 315 NKGNHCGIAS 324 + NHCGI S Sbjct: 242 GE-NHCGIES 250 >1MIR-A nrPDB Length = 322 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 85/309 (27%), Positives = 145/309 (46%), Gaps = 56/309 (18%) Query: 56 LKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRIL 115 + ++ N G + Y++ +++L + +++ ++P + + + + N L Sbjct: 14 INYINKQNTTWQAGRNFYNVDISYLKKLCG----TVLGGPKLPER----VGFSEDIN--L 63 Query: 116 PDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT-GKL-VSLSAQNLVD 169 P+S D RE+ + +++ QGSCG+ WAF AV A+ ++ + T G++ V +SA++L+ Sbjct: 64 PESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 123 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PY---------------- 206 C + G+ GCNGG+ + A+ + KG+ S Y PY Sbjct: 124 CCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPC 181 Query: 207 --KAMDQKCQ------YDSKYRAATCSKYTELPYGREDVLKEAVAN---KGPVSVGVDAR 255 + KC Y + Y+ YT Y D KE +A GPV G Sbjct: 182 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTS--YSVSDSEKEIMAEIYKNGPVE-GAFTV 238 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 239 FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRG 298 Query: 316 KGNHCGIAS 324 + NHCGI S Sbjct: 299 E-NHCGIES 306 >4I05-A nrPDB Length = 285 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 118/256 (46%), Gaps = 52/256 (20%) Query: 112 NRILPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQ 165 N +P S D R+K + ++ Q CG+CWAF AV A+ + +++G + V LSA Sbjct: 31 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAV 90 Query: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDAS---------YPYKAMDQKCQYD 216 +L+ C E G GC GG + A+ Y + +GI + +S YP+ KC++ Sbjct: 91 DLLSC-CESCG-LGCEGGILGPAWDYWV-KEGIVTGSSKENHAGCEPYPFP----KCEHH 143 Query: 217 SKYR--------------AATCSKYTELPYGR--------------EDVLKEAVANKGPV 248 +K + TC K + PY + E +++ + GPV Sbjct: 144 TKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPV 203 Query: 249 SVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEG 308 G + F Y+SG+Y + H + ++G+G N YWL+ NSW ++GE G Sbjct: 204 EAGFTV-YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENG 262 Query: 309 YIRMARNKGNHCGIAS 324 Y R+ R + + C I S Sbjct: 263 YFRIVRGR-DECSIES 277 >5OGQ-A nrPDB Length = 254 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 72/253 (28%), Positives = 117/253 (46%), Gaps = 52/253 (20%) Query: 115 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLV 168 +P S D R+K + ++ Q CG+CWAF AV A+ + +++G + V LSA +L+ Sbjct: 3 IPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVDLL 62 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDAS---------YPYKAMDQKCQYDSKY 219 C E G GC GG + A+ Y + +GI + +S YP+ KC++ +K Sbjct: 63 SC-CESCG-LGCEGGILGPAWDYWV-KEGIVTGSSKENHAGCEPYPF----PKCEHHTKG 115 Query: 220 R--------------AATCSKYTELPYGR--------------EDVLKEAVANKGPVSVG 251 + TC K + PY + E +++ + GPV G Sbjct: 116 KYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAG 175 Query: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 + F Y+SG+Y + H + ++G+G N YWL+ NSW ++GE GY R Sbjct: 176 FTV-YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFR 234 Query: 312 MARNKGNHCGIAS 324 + R + + C I S Sbjct: 235 IVRGR-DECSIES 246 >4I04-A nrPDB Length = 323 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 52/253 (20%) Query: 115 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLV 168 +P S D R+K + ++ Q CG+ WAF AV A+ + +++G + V LSA +L+ Sbjct: 72 IPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLL 131 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDAS---------YPYKAMDQKCQYDSKY 219 C E G GC GG + A+ Y + +GI + +S YP+ KC++ +K Sbjct: 132 SC-CESCG-LGCEGGILGPAWDYWV-KEGIVTGSSKENHAGCEPYPF----PKCEHHTKG 184 Query: 220 R--------------AATCSKYTELPYGR--------------EDVLKEAVANKGPVSVG 251 + TC K + PY + E +++ + GPV G Sbjct: 185 KYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAG 244 Query: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 + F Y+SG+Y + H + ++G+G N YWL+ NSW ++GE GY R Sbjct: 245 FTV-YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFR 303 Query: 312 MARNKGNHCGIAS 324 + R + + C I S Sbjct: 304 IVRGR-DECSIES 315 >4HWY-A nrPDB Length = 340 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 69/238 (28%), Positives = 103/238 (43%), Gaps = 36/238 (15%) Query: 115 LPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG-KLVSLSAQNLVD 169 LP S D W + ++ Q +CG+CWA +A A+ + G + V +SA +L+ Sbjct: 94 LPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLA 153 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT- 228 C ++ GCNGG A+ Y + G+ SD PY SK CS++ Sbjct: 154 CCSDC--GDGCNGGDPDRAWAYF-SSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNF 210 Query: 229 ------------ELPY------------GREDVLKEAVANKGPVSVGVDARHPSFFLYRS 264 +P G +D ++E + +GP V D + F Y S Sbjct: 211 DTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRE-LFFRGPFEVAFDV-YEDFIAYNS 268 Query: 265 GVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322 GVY+ S H V +VG+G NG YW + NSW +G +GY + R + CGI Sbjct: 269 GVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYF-LIRRGSSECGI 325 >2DCB-A nrPDB Length = 256 Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 123/250 (49%), Gaps = 46/250 (18%) Query: 115 LPDSVDWREK--GCVT--EVKYQGSCGACWAFSAVGALEAQLKLKT-GKL-VSLSAQNLV 168 LP+S D RE+ C T E++ QGSCG+CWAF AV A+ ++ + + G++ V +SA++++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PY--------------- 206 GCNGGF + A+ + KG+ S Y PY Sbjct: 61 T-CCGGECGDGCNGGFPSGAWNFWT-KKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPP 118 Query: 207 ---KAMDQKCQ------YDSKYRAAT---CSKYTELPYGREDVLKEAVANKGPVSVGVDA 254 + KC Y Y+ CS Y+ + ++++ E N GPV G + Sbjct: 119 CTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYS-VANNEKEIMAEIYKN-GPVE-GAFS 175 Query: 255 RHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 314 + F LY+SGVY S H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 176 VYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILR 235 Query: 315 NKGNHCGIAS 324 + +HCGI S Sbjct: 236 GQ-DHCGIES 244 >4OEL-A nrPDB Length = 370 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 50/163 (30%), Positives = 84/163 (51%), Gaps = 13/163 (7%) Query: 115 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT--GKLVSLSAQNLVD 169 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 207 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 266 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 229 CS +Y +GC GGF + G+ +A +PY D C+ S+Y Sbjct: 267 CS--QYA-QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHY 323 Query: 230 LP--YG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268 + YG E ++K + + GP++V + + F Y+ G+Y+ Sbjct: 324 VGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYH 365 >4CDF-B nrPDB Length = 166 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 51/169 (30%), Positives = 83/169 (49%), Gaps = 25/169 (14%) Query: 115 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT--GKLVSLSAQNLVD 169 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 3 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 62 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ--------YDSKYRA 221 CS +GC GGF + G+ +A +PY D C+ Y S+Y Sbjct: 63 CSQYA---QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH- 118 Query: 222 ATCSKYTELPYG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268 Y YG E ++K + + GP++V + + F Y+ G+Y+ Sbjct: 119 -----YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYH 161 >1CSB-B nrPDB Length = 205 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 88/198 (44%), Gaps = 38/198 (19%) Query: 160 VSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQK 212 V +SA++L+ C G+ GCNGG+ A+ + KG+ S Y PY + Sbjct: 3 VEVSAEDLLTCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 213 CQYDSKYRAAT-------CSKYTELPYG-------------------REDVLKEAVANKG 246 + T CSK E Y +D++ E N G Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-G 119 Query: 247 PVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGE 306 PV G + + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ Sbjct: 120 PVE-GAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 178 Query: 307 EGYIRMARNKGNHCGIAS 324 G+ ++ R + +HCGI S Sbjct: 179 NGFFKILRGQ-DHCGIES 195 >5FPW-A nrPDB Length = 321 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 108/248 (43%), Gaps = 38/248 (15%) Query: 115 LPDSVDWREK--GCVT--EVKYQGSCGACWAFSAVGALEAQLKLKTG-KLVSLSAQNLVD 169 LP+S D EK C T E+ Q +C A WA S + + G + + +SA +L+ Sbjct: 75 LPESFDSAEKWPNCPTIREIADQSACRASWAVSTASVISDRYCTVGGVQQLRISAAHLL- 133 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPY-------------KAMDQKCQYD 216 S K GC GGF A++Y ++ GI S PY K K +D Sbjct: 134 -SCCKQCGGGCKGGFPGFAWRYYVE-YGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFD 191 Query: 217 SKYRAATCS-------KYTE-----LPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRS 264 + ATC+ KY L +G ED +E N GP V V + F Y+S Sbjct: 192 TPKCQATCTDKSIPLVKYRGSATYLLLHGEEDYKRELYFN-GPF-VAVFYVYTDLFAYKS 249 Query: 265 GVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIA- 323 GVY V VVG+G LNG YW V N+W ++G +GY+ + R N C I Sbjct: 250 GVYRHVDGDFLGGTAVKVVGWGKLNGTPYWKVANTWDTDWGMDGYLLILRGN-NECNIEH 308 Query: 324 -SFPSYPE 330 F PE Sbjct: 309 LGFAGTPE 316 >1SP4-B nrPDB Length = 205 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 37/101 (36%), Positives = 58/101 (57%), Gaps = 4/101 (3%) Query: 224 CSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVV 283 CS Y+ + ++++ E N GPV G + + F LY+SGVY S H + ++ Sbjct: 100 CSSYS-VANNEKEIMAEIYKN-GPVE-GAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRIL 156 Query: 284 GYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIAS 324 G+G NG YWLV NSW ++G+ G+ ++ R + +HCGI S Sbjct: 157 GWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQ-DHCGIES 196 >3CH2-X nrPDB Length = 265 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 58/234 (24%), Positives = 105/234 (44%), Gaps = 38/234 (16%) Query: 123 EKGCVT--EVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 180 E C++ +V+ QG+C W F++ LE +K + +SA + +C ++ ++ C Sbjct: 15 ENNCISNLQVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDR-C 73 Query: 181 NGGFMTTAFQYIIDNKG-IDSDASYPY-----------------------KAMDQKCQYD 216 + G F II++ G + ++++YPY K + K + + Sbjct: 74 DEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 133 Query: 217 S----KYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC 272 S Y A ++ + ++K V NKG V + A + + + SG + C Sbjct: 134 SLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEF-SGKKVQNLC 192 Query: 273 TQNV-NHGVLVVGYGDL-----NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHC 320 + +H V +VGYG+ K YW+V+NSWG +G+EGY ++ HC Sbjct: 193 GDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >4OEM-B nrPDB Length = 70 Score = 55.5 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 26/50 (52%), Positives = 33/50 (66%), Gaps = 3/50 (6%) Query: 277 NHGVLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIAS 324 NH VL+VGYG +G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 10 NHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIES 58 >4CI7-A nrPDB Length = 470 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 67/238 (28%), Positives = 98/238 (41%), Gaps = 41/238 (17%) Query: 97 VPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKT 156 +PS ++ ++ Y NP + G T K QGS W+FS + LEA LKLK Sbjct: 59 LPSAYKSSVAY--NPMDL----------GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKG 106 Query: 157 GKLVSLSAQNLVDCST-EKYG--NKGCNGGFMTTAFQYIIDNKG--IDSDASYPYKAMDQ 211 LS ++L +T KYG +G TA Y+ G ++ D Y K+ Q Sbjct: 107 YGTYDLSEEHLRWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQ 166 Query: 212 KCQYDSKYRAA----TCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVY 267 S A + L +E V K A+ G V+ G A + ++F Y Sbjct: 167 GATKPSNMDTAPTQFNVTDVVRLNKDKETV-KNAIMQYGSVTSGY-AHYSTYFNKDETAY 224 Query: 268 YEPSCTQN---VNHGVLVVGYGDLNGKE------------YWLVKNSWGHNFGEEGYI 310 +CT +NH V +VG+ D K+ WLVK+SWG +G+ Sbjct: 225 ---NCTNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFF 279 >4D59-A nrPDB Length = 406 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 87/210 (41%), Gaps = 29/210 (13%) Query: 125 GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCST-EKYG--NKGCN 181 G T K QGS W+FS + LEA LKLK LS ++L +T KYG + Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 182 GGFMTTAFQYIIDNKG--IDSDASYPYKAMDQKCQYDSKYRAA----TCSKYTELPYGRE 235 G TA Y+ G ++ D Y K+ Q S A + L +E Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKE 130 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN---VNHGVLVVGYGDLNGKE 292 V K A+ G V+ G A + ++F Y +CT +NH V +VG+ D K+ Sbjct: 131 TV-KNAIMQYGSVTSGY-AHYSTYFNKDETAY---NCTNKRAPLNHAVAIVGWDDNYSKD 185 Query: 293 ------------YWLVKNSWGHNFGEEGYI 310 WLVK+SWG +G+ Sbjct: 186 NFASDVKPESNGAWLVKSSWGEFNSMKGFF 215 >2L95-A nrPDB Length = 80 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Query: 25 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMT 84 D W +K + K Y E E+ +RR I+ ++ + HN + G ++ +G+NHL D+T Sbjct: 7 DEEWVEYKSKFDKNY-EAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLT 65 Query: 85 SEEVMSLMSSLRVP 98 EE + S +VP Sbjct: 66 PEE-FAQRSGKKVP 78 >3OIS-A nrPDB Length = 291 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 21/122 (17%) Query: 204 YPYKAMDQKCQYDSKYRAATCSKYTELPYGREDV--LKEAVANKGPVSVGVDARHPSFFL 261 +P A K D Y+ A K TE +D+ LK +A P G F + Sbjct: 158 FPPGAPASKKPSDQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVFG-------FSV 210 Query: 262 YRSGV------YYEPSCTQNVN----HGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 Y S V P T+N H VL VGY D ++ ++NSWG+N GE+GY Sbjct: 211 YNSWVGNNSLPVRIPLPTKNDTLEGGHAVLCVGYDD--EIRHFRIRNSWGNNVGEDGYFW 268 Query: 312 MA 313 M Sbjct: 269 MP 270 >4K7C-A nrPDB Length = 446 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 276 VNHGVLVVGYGDLNGKEY-WLVKNSWGHNFGEEGYI 310 + H +++ G ++GK W V+NSWG GE+GY Sbjct: 362 MTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >5WDK-A nrPDB Length = 401 Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Query: 277 NHGVLVVGYG-DLNGKEYWLVKNSWGHN 303 +HG+ + G D G EY++VKNSWG N Sbjct: 335 DHGMQIYGIAKDQEGNEYYMVKNSWGTN 362 Score = 30.8 bits (68), Expect = 0.94, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 1/32 (3%) Query: 127 VTEVKYQGSCGACWAFSAVGALEAQLKLKTGK 158 +T VK Q G CW +S+ LE++L L+ GK Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESEL-LRMGK 70 >5B04-A nrPDB Length = 341 Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 28/55 (50%) Query: 199 DSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVD 253 D + + P A++ Q S+ +A T S++ ++ + LKE V N +S G D Sbjct: 30 DPEITMPVAAIEALVQLLSRSQAKTISEFMDILQNGSNTLKEGVQNNISLSAGCD 84 >4UYP-A nrPDB Length = 151 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 5/96 (5%) Query: 159 LVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN-KGIDSD---ASYPYKAMDQKCQ 214 + S+ A +L++ +++ GF + F+ +D + IDSD A+ +K D + Sbjct: 47 VASIDAGSLIENASDFTTYYNNENGFASMTFEAPVDRARIIDSDGVFATINFKVSDS-AK 105 Query: 215 YDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSV 250 Y T S YT Y D +K V N G + V Sbjct: 106 VGELYNITTNSAYTSFYYSGTDEIKNVVYNDGKIEV 141 >1HP1-A nrPDB Length = 516 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 21/114 (18%) Query: 23 TLDHHWHLWKKTYGK---QYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDL---- 75 T DHH H W+ YG+ ++ + +R+ + + ++L + + G+ DL Sbjct: 14 TNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAE 73 Query: 76 ----GMNHLG----DMTSEEVMSLMSSLRVPSQWQR------NITYKSNPNRIL 115 GMN +G + + E + ++ LR +W + NI KS R+ Sbjct: 74 PDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLF 127 >4WD1-A nrPDB Length = 658 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 30/84 (35%), Gaps = 14/84 (16%) Query: 228 TELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLV----- 282 TE P G D A+ PV V HP + LY SG P G+LV Sbjct: 237 TEAPDGTLDWETLTAADAEPVYEQVPFDHPLWVLYSSGTTGLPKAIVQSQGGILVEHLKQ 296 Query: 283 ------VGYGDLNGKEYWLVKNSW 300 +G GD + +W W Sbjct: 297 LGLHCDLGPGD---RFFWYTSTGW 317 >2CB5-A nrPDB Length = 453 Score = 27.7 bits (60), Expect = 7.5, Method: Compositional matrix adjust. Identities = 10/20 (50%), Positives = 14/20 (70%) Query: 294 WLVKNSWGHNFGEEGYIRMA 313 W V+NSWG + G +GY+ M Sbjct: 391 WRVENSWGEDHGHKGYLCMT 410 >4P1X-A nrPDB Length = 309 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 20/41 (48%) Query: 265 GVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFG 305 G Y S + N V VV Y N E + V+N+ G+ FG Sbjct: 89 GAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFG 129 >4F3Z-A nrPDB Length = 329 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 144 AVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY--GNKGCNGGFMTTAFQYIIDNKGIDSD 201 +V LE + K KL ++ +L C+ + GN C F +++ YI++ D+ Sbjct: 31 SVNLLEDRHNGKLCKLRGVAPLHLGKCNIAGWLLGNPECESLFTASSWSYIVETSSSDNG 90 Query: 202 ASYP 205 YP Sbjct: 91 TCYP 94 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2C0Y-A nrPDB 487 e-138 7PCK-A nrPDB 424 e-119 1CJL-A nrPDB 408 e-114 3QJ3-A nrPDB 380 e-106 2O6X-A nrPDB 375 e-104 6CZS-A nrPDB 371 e-103 3QT4-A nrPDB 369 e-103 4P6E-A nrPDB 360 e-100 4QRX-A nrPDB 360 e-100 1PCI-A nrPDB 350 5e-97 3HWN-A nrPDB 346 1e-95 4BS5-A nrPDB 338 2e-93 5EF4-A nrPDB 324 4e-89 3OF9-A nrPDB 318 2e-87 3KFQ-A nrPDB 315 3e-86 5JA7-A nrPDB 311 2e-85 1S4V-A nrPDB 306 8e-84 5JT8-A nrPDB 304 3e-83 6BKI-A nrPDB 304 3e-83 1CQD-A nrPDB 303 8e-83 2VHS-A nrPDB 302 2e-82 4YYR-A nrPDB 299 1e-81 3P5W-A nrPDB 298 2e-81 2FO5-A nrPDB 296 7e-81 2PNS-A nrPDB 293 5e-80 1IWD-A nrPDB 292 1e-79 1AEC-A nrPDB 291 2e-79 3BCN-A nrPDB 290 4e-79 4YYW-A nrPDB 289 1e-78 1O0E-A nrPDB 288 2e-78 3F75-A nrPDB 288 3e-78 1NB3-A nrPDB 287 5e-78 2ACT-A nrPDB 285 2e-77 1YAL-A nrPDB 279 1e-75 2BDZ-A nrPDB 273 5e-74 1PPO-A nrPDB 273 1e-73 1XKG-A nrPDB 271 3e-73 4YYQ-A nrPDB 270 5e-73 6MIS-A nrPDB 268 2e-72 5A24-A nrPDB 266 7e-72 2CIO-A nrPDB 264 3e-71 1GEC-E nrPDB 259 8e-70 2B1M-A nrPDB 256 1e-68 1ICF-A nrPDB 256 1e-68 3U8E-A nrPDB 254 3e-68 1MIR-A nrPDB 247 7e-66 3PBH-A nrPDB 246 2e-65 3IOQ-A nrPDB 245 2e-65 6EXO-A nrPDB 242 1e-64 3PDF-A nrPDB 239 1e-63 3BPF-A nrPDB 235 2e-62 4PI3-A nrPDB 235 2e-62 1JQP-A nrPDB 233 8e-62 3BPM-A nrPDB 229 1e-60 1M6D-A nrPDB 224 4e-59 5VCN-A nrPDB 223 1e-58 5VPK-A nrPDB 221 4e-58 1CPJ-A nrPDB 214 4e-56 4I05-A nrPDB 213 9e-56 4HWY-A nrPDB 212 1e-55 3CBK-A nrPDB 212 2e-55 4I04-A nrPDB 212 2e-55 5OGQ-A nrPDB 204 5e-53 2DCB-A nrPDB 187 5e-48 5FPW-A nrPDB 172 1e-43 1DEU-A nrPDB 172 2e-43 4OEL-A nrPDB 170 8e-43 5I4H-A nrPDB 169 2e-42 1EF7-A nrPDB 169 2e-42 4CDF-B nrPDB 169 2e-42 1CSB-B nrPDB 156 1e-38 4CI7-A nrPDB 150 7e-37 3CH2-X nrPDB 150 1e-36 4D59-A nrPDB 147 7e-36 5I4H-B nrPDB 147 7e-36 1SP4-B nrPDB 129 1e-30 2L95-A nrPDB 86 3e-17 4OEM-B nrPDB 82 5e-16 Sequences not found previously or not previously below threshold: 3OIS-A nrPDB 56 3e-08 4K7C-A nrPDB 44 1e-04 5WDK-A nrPDB 43 2e-04 2CB5-A nrPDB 35 0.040 2QGM-A nrPDB 35 0.046 4YE5-A nrPDB 33 0.14 3RXZ-A nrPDB 32 0.41 4W8N-A nrPDB 31 0.89 2WR0-A nrPDB 30 1.1 2XGT-A nrPDB 30 1.1 1A6R-A nrPDB 30 1.3 4KPS-A nrPDB 30 1.6 2UXY-A nrPDB 30 1.7 1L9N-A nrPDB 30 1.7 2Z51-A nrPDB 30 2.0 1G0D-A nrPDB 29 2.7 3UKH-A nrPDB 29 3.3 5AJK-A nrPDB 28 4.3 3PZL-A nrPDB 28 4.5 5ZRD-A nrPDB 28 5.0 5DMY-A nrPDB 28 7.3 1UUQ-A nrPDB 27 8.8 >2C0Y-A nrPDB Length = 315 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 314/315 (99%), Positives = 314/315 (99%) Query: 17 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 76 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG Sbjct: 1 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 60 Query: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC 136 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC Sbjct: 61 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC 120 Query: 137 GACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK 196 GA WAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK Sbjct: 121 GAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK 180 Query: 197 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH 256 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH Sbjct: 181 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH 240 Query: 257 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 316 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK Sbjct: 241 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 300 Query: 317 GNHCGIASFPSYPEI 331 GNHCGIASFPSYPEI Sbjct: 301 GNHCGIASFPSYPEI 315 >7PCK-A nrPDB Length = 314 Score = 424 bits (1091), Expect = e-119, Method: Composition-based stats. Identities = 178/317 (56%), Positives = 224/317 (70%), Gaps = 6/317 (1%) Query: 18 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 77 L+ + LD HW LWKKT+ KQY K +E RRLIWEKNLK++ +HNLE S+G+H+Y+L M Sbjct: 1 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 60 Query: 78 NHLGDMTSEEVMSLMSSLRVPSQWQRN--ITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135 NHLGDMTSEEV+ M+ L+VP R+ Y PDSVD+R+KG VT VK QG Sbjct: 61 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 120 Query: 136 CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195 CG+CWAFS+VGALE QLK KTGKL++LS QNLVDC +E N GC GG+MT AFQY+ N Sbjct: 121 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---NDGCGGGYMTNAFQYVQKN 177 Query: 196 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 255 +GIDS+ +YPY ++ C Y+ +AA C Y E+P G E LK AVA GPVSV +DA Sbjct: 178 RGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDAS 237 Query: 256 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 314 SF Y GVYY+ SC + N+NH VL VGYG G ++W++KNSWG N+G +GYI MAR Sbjct: 238 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 297 Query: 315 NKGNHCGIASFPSYPEI 331 NK N CGIA+ S+P++ Sbjct: 298 NKNNACGIANLASFPKM 314 >1CJL-A nrPDB Length = 312 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 159/321 (49%), Positives = 215/321 (66%), Gaps = 19/321 (5%) Query: 21 DPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHL 80 D +L+ W WK + + Y NEE RR +WEKN+K + LHN E+ G HS+ + MN Sbjct: 1 DHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAF 59 Query: 81 GDMTSEEVMSLMSS-----LRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135 GDMTSEE +M+ R +Q + Y++ P SVDWREKG VT VK QG Sbjct: 60 GDMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEA------PRSVDWREKGYVTPVKNQGQ 113 Query: 136 CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195 CG+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+GCNGG M AFQY+ DN Sbjct: 114 CGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPE-GNEGCNGGLMDYAFQYVQDN 172 Query: 196 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 255 G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV +DA Sbjct: 173 GGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAG 231 Query: 256 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFGEEGYI 310 H SF Y+ G+Y+EP C +++++HGVLVVGYG + +G +YWLVKNSWG +G GY+ Sbjct: 232 HESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYV 291 Query: 311 RMARNKGNHCGIASFPSYPEI 331 +MA+++ NHCGIAS SYP + Sbjct: 292 KMAKDRRNHCGIASAASYPTV 312 >3QJ3-A nrPDB Length = 331 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 138/326 (42%), Positives = 186/326 (57%), Gaps = 14/326 (4%) Query: 16 AQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDL 75 + W +K TY + Y EE R+ I++K L+ HN ++ G+ SY L Sbjct: 10 GSALPSTFVAEKWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTL 69 Query: 76 GMNHLGDMTSEEVMSLMSSLRVPSQWQRN-ITYKS------NPNRILPDSVDWREKGCVT 128 G+N DMT EE+ + L +P+ +N I K+ N + P S DWR++G V+ Sbjct: 70 GVNLFTDMTPEEMKAYTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMVS 129 Query: 129 EVKYQGSCGACWAFSAVGALEAQLKLKTGKLV--SLSAQNLVDCSTEKYGNKGCNGGFMT 186 VK QGSCG+ WAFS+ GA+E+Q+K+ G S+S Q LVDC GC+GG+M Sbjct: 130 PVKNQGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVPNA---LGCSGGWMN 186 Query: 187 TAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKG 246 AF Y+ N GIDS+ +YPY+ D C YD AA S Y L E++L + VA KG Sbjct: 187 DAFTYVAQNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKG 246 Query: 247 PVSVGVDARHPSFFLYRSGVYYEPSCTQN-VNHGVLVVGYGDLNGKEYWLVKNSWGHNFG 305 PV+V DA F Y GVYY P+C N H VL+VGYG+ NG++YWLVKNSWG +G Sbjct: 247 PVAVAFDA-DDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWG 305 Query: 306 EEGYIRMARNKGNHCGIASFPSYPEI 331 +GY ++ARN NHCGIA S P + Sbjct: 306 LDGYFKIARNANNHCGIAGVASVPTL 331 >2O6X-A nrPDB Length = 310 Score = 375 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 138/310 (44%), Positives = 188/310 (60%), Gaps = 8/310 (2%) Query: 25 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMT 84 D WH WK+ Y K+Y +++ RR IWEKN+K + HNL H +G+ +Y LG+N DMT Sbjct: 2 DDLWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 85 SEEVMSLM--SSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAF 142 EE + R + Y++N NR +PD +DWRE G VTEVK QG+CG+ WAF Sbjct: 61 FEEFKAKYLTEMSRASDILSHGVPYEAN-NRAVPDKIDWRESGYVTEVKDQGNCGSGWAF 119 Query: 143 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 202 S G +E Q +S S Q LVDCS +GN GC GG M A+QY+ G+++++ Sbjct: 120 STTGTMEGQYMKNERTSISFSEQQLVDCSRP-WGNNGCGGGLMENAYQYL-KQFGLETES 177 Query: 203 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 262 SYPY A++ +C+Y+ + A + + + G E LK V +GP +V VD F +Y Sbjct: 178 SYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVE-SDFMMY 236 Query: 263 RSGVYYEPSCTQN-VNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCG 321 RSG+Y +C+ VNH VL VGYG G +YW+VKNSWG ++GE GYIRM RN+GN CG Sbjct: 237 RSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCG 296 Query: 322 IASFPSYPEI 331 IAS S P + Sbjct: 297 IASLASLPMV 306 >6CZS-A nrPDB Length = 335 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 120/330 (36%), Positives = 171/330 (51%), Gaps = 17/330 (5%) Query: 7 VLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEH 66 +L V A+L + H+ W + K Y E R + N + + HN Sbjct: 14 LLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYST-EEYHHRLQTFASNWRKINAHN--- 69 Query: 67 SMGMHSYDLGMNHLGDMTSEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREK 124 G H++ + +N DM+ E+ L S + S + N + P P SVDWR+K Sbjct: 70 -NGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY---PPSVDWRKK 125 Query: 125 G-CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGG 183 G V+ VK QG+CG+ W FS GALE+ + + TGK++SL+ Q LVDC+ + + N GC GG Sbjct: 126 GNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHGCQGG 184 Query: 184 FMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVA 243 + AF+YI+ NKGI + +YPY+ D C++ + E+ + EAVA Sbjct: 185 LPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVA 244 Query: 244 NKGPVSVGVDARHPSFFLYRSGVYYEPSCT---QNVNHGVLVVGYGDLNGKEYWLVKNSW 300 PVS + F +YR+G+Y SC VNH VL VGYG+ NG YW+VKNSW Sbjct: 245 LYNPVSFAFEVTQ-DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSW 303 Query: 301 GHNFGEEGYIRMARNKGNHCGIASFPSYPE 330 G +G GY + R K N CG+A+ SYP Sbjct: 304 GPQWGMNGYFLIERGK-NMCGLAACASYPI 332 >3QT4-A nrPDB Length = 329 Score = 369 bits (948), Expect = e-103, Method: Composition-based stats. Identities = 134/315 (42%), Positives = 188/315 (59%), Gaps = 7/315 (2%) Query: 20 KDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNH 79 W +K T+ K Y EE R+LI++ N+ + HN + G +Y MN Sbjct: 19 PKSLFQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQ 78 Query: 80 LGDMTSEEVMSLMSSLRVPSQWQRNITYKS--NPNRILPDSVDWREKGCVTEVKYQGSCG 137 GDM+ EE ++ ++ + + + L SVDWR V+EVK QG CG Sbjct: 79 FGDMSKEEFLAYVNRGKAQKPKHPENLRMPYVSSKKPLAASVDWRS-NAVSEVKDQGQCG 137 Query: 138 ACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKG 197 + W+FS GA+E QL L+ G+L SLS QNL+DCS+ YGN GC+GG+M +AF YI + G Sbjct: 138 SSWSFSTTGAVEGQLALQRGRLTSLSEQNLIDCSS-SYGNAGCDGGWMDSAFSYI-HDYG 195 Query: 198 IDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHP 257 I S+++YPY+A C++DS T S Y +LP G E+ L +AV GPV+V +DA Sbjct: 196 IMSESAYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDE 255 Query: 258 SFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 316 Y G++Y+ +C Q ++NHGVLVVGYG NG++YW++KNSWG +GE GY R RN Sbjct: 256 -LQFYSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWRQVRNY 314 Query: 317 GNHCGIASFPSYPEI 331 GN+CGIA+ SYP + Sbjct: 315 GNNCGIATAASYPAL 329 >4P6E-A nrPDB Length = 230 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 109 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 168 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV Sbjct: 1 SNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 60 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 228 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 120 Query: 229 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL 288 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL Sbjct: 121 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL 180 Query: 289 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI Sbjct: 181 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >4QRX-A nrPDB Length = 363 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 113/320 (35%), Positives = 170/320 (53%), Gaps = 21/320 (6%) Query: 17 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 76 L L + W + K YK +E+ R I++ NLK++ N ++ +SY LG Sbjct: 55 DLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKN----NSYWLG 110 Query: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKS---NPNRILPDSVDWREKGCVTEVKYQ 133 +N DM+++E + + ++Y+ + + +P+ VDWR+KG VT VK Q Sbjct: 111 LNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQ 170 Query: 134 GSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYII 193 GSCG+ WAFSAV +E+ +K++TG L S Q L+DC Y GCNGG+ +A Q ++ Sbjct: 171 GSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSY---GCNGGYPWSALQ-LV 226 Query: 194 DNKGIDSDASYPYKAMDQKCQYDSKYR-AATCSKYTELPYGREDVLKEAVANKGPVSVGV 252 GI +YPY+ + + C+ K AA ++ E L ++AN+ PVSV + Sbjct: 227 AQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQ-PVSVVL 285 Query: 253 DARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 +A F LYR G++ P C V+H V VGYG Y L++NSWG +GE GYIR+ Sbjct: 286 EAAGKDFQLYRGGIFVGP-CGNKVDHAVAAVGYGP----NYILIRNSWGTGWGENGYIRI 340 Query: 313 ARNKGNH---CGIASFPSYP 329 R GN CG+ + YP Sbjct: 341 KRGTGNSYGVCGLYTSSFYP 360 >1PCI-A nrPDB Length = 322 Score = 350 bits (898), Expect = 5e-97, Method: Composition-based stats. Identities = 115/322 (35%), Positives = 165/322 (51%), Gaps = 20/322 (6%) Query: 17 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 76 L L ++ W + K Y+ +E+ R I++ NL ++ N ++ +SY LG Sbjct: 11 DLTSTERLIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKN----NSYWLG 66 Query: 77 MNHLGDMTSEEVMSLMSSL----RVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKY 132 +N D++++E + + + N LP++VDWR+KG VT V++ Sbjct: 67 LNEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVN--LPENVDWRKKGAVTPVRH 124 Query: 133 QGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYI 192 QGSCG+CWAFSAV +E K++TGKLV LS Q LVDC GC GG+ A +Y+ Sbjct: 125 QGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRS---HGCKGGYPPYALEYV 181 Query: 193 IDNKGIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251 N GI + YPYKA C+ S + E L A+A + PVSV Sbjct: 182 AKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAKQ-PVSVV 239 Query: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 V+++ F LY+ G++ P C V+ V VGYG GK Y L+KNSWG +GE+GYIR Sbjct: 240 VESKGRPFQLYKGGIFEGP-CGTKVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIR 298 Query: 312 MARNKGNH---CGIASFPSYPE 330 + R GN CG+ YP Sbjct: 299 IKRAPGNSPGVCGLYKSSYYPT 320 >3HWN-A nrPDB Length = 258 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 136/266 (51%), Positives = 182/266 (68%), Gaps = 18/266 (6%) Query: 76 GMNHLGDMTSEEVMSLMSS-----LRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEV 130 MN GDMTSEE +M+ R +Q + Y++ P SVDWREKG VT V Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRSVDWREKGYVTPV 54 Query: 131 KYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQ 190 K QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+GCNGG M AFQ Sbjct: 55 KNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNEGCNGGLMDYAFQ 113 Query: 191 YIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSV 250 Y+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV Sbjct: 114 YVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISV 172 Query: 251 GVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFG 305 +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +YWLVKNSWG +G Sbjct: 173 AIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWG 232 Query: 306 EEGYIRMARNKGNHCGIASFPSYPEI 331 GY++MA+++ NHCGIAS SYP + Sbjct: 233 MGGYVKMAKDRRNHCGIASAASYPTV 258 >4BS5-A nrPDB Length = 225 Score = 338 bits (868), Expect = 2e-93, Method: Composition-based stats. Identities = 181/225 (80%), Positives = 200/225 (88%), Gaps = 1/225 (0%) Query: 108 KSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNL 167 +S NR LPD+VDWREKGCVTEVKYQGSCGACWAFSAVGALE QLKLKTGKL+SLSAQNL Sbjct: 1 RSYSNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNL 60 Query: 168 VDCSTE-KYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSK 226 VDCS E KYGNKGC GG+MT AFQYIIDN GI++DASYPYKAMD+KC Y+SK RAATCS+ Sbjct: 61 VDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSR 120 Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG 286 Y +LP+G ED LKEAVA KGPVSVG+DA H SFF Y+SGVY +PSCT NVNHGVLVVGYG Sbjct: 121 YIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYG 180 Query: 287 DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 L+GK+YWLVKNSWG NFG++GYIRMARN NHCGIAS+ SYPEI Sbjct: 181 TLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >5EF4-A nrPDB Length = 385 Score = 324 bits (830), Expect = 4e-89, Method: Composition-based stats. Identities = 110/330 (33%), Positives = 166/330 (50%), Gaps = 28/330 (8%) Query: 17 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 76 +L + + W++ + + + R +++ N++ + N Y L Sbjct: 28 ELESEEGFMGMYDRWREQHNIEMRSPE----RFNVFKYNVRRIHESNKMDKP----YKLK 79 Query: 77 MNHLGDMTSEEVMSLMSSLRVPS----QWQRNITYKSNPNR--------ILPDSVDWREK 124 +N DMT+ E ++ ++ ++ + + ++PN+ +PD VDWREK Sbjct: 80 VNEFADMTNLEFVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREK 139 Query: 125 GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGF 184 VT+VK QG CG+CWAF+AV ALE ++TGKLV S Q LVDC N GC+GG Sbjct: 140 NAVTDVKGQGGCGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCDMT---NAGCDGGL 196 Query: 185 MTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVAN 244 M AF Y+I + GI +ASYPY + C +P E+ L++AVA+ Sbjct: 197 MEPAFTYVIKHGGIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAVAH 256 Query: 245 KGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG-DLNGKEYWLVKNSWGHN 303 + PV+ G+ Y GVY C NHGV +VGYG + G ++W VKNSWG Sbjct: 257 Q-PVATGIQLSGHGLQFYSEGVYTGD-CGTEPNHGVGIVGYGENEKGIKFWTVKNSWGPT 314 Query: 304 FGEEGYIRMARN--KGNHCGIASFPSYPEI 331 +GE+GYI + R K CG+A S+P + Sbjct: 315 WGEKGYIHLQRGARKEGLCGVAMHSSFPIM 344 >3OF9-A nrPDB Length = 221 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 123/221 (55%), Positives = 163/221 (73%), Gaps = 7/221 (3%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 3 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 120 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNG 290 L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + Sbjct: 121 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 180 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 181 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >3KFQ-A nrPDB Length = 221 Score = 315 bits (806), Expect = 3e-86, Method: Composition-based stats. Identities = 125/222 (56%), Positives = 162/222 (72%), Gaps = 6/222 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP SVDWR+KG VT VK Q CG+CWAFSA GALE Q+ KTGKLVSLS QNLVDCS + Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 GN+GCNGGFM AFQY+ +N G+DS+ SYPY A+D+ C+Y + A + +T + G+ Sbjct: 61 -GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGK 119 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYG----DLN 289 E L +AVA GP+SV +DA H SF Y+SG+Y+EP C+ N++HGVLVVGYG + + Sbjct: 120 EKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSD 179 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 +YWLVKNSWG +G GY+++A++K NHCGIA+ SYP + Sbjct: 180 NSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >5JA7-A nrPDB Length = 223 Score = 311 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 126/226 (55%), Positives = 157/226 (69%), Gaps = 4/226 (1%) Query: 107 YKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQN 166 Y PDSVD+R+KG VT VK QG CG+ WAFS+VGALE QLK KTGKL++LS QN Sbjct: 1 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQN 60 Query: 167 LVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSK 226 LVDC +E N GC GG+MT AFQY+ N+GIDS+ +YPY ++ C Y+ +AA C Sbjct: 61 LVDCVSE---NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRG 117 Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGY 285 Y E+P G E LK AVA GPVSV +DA SF Y GVYY+ SC + N+NH VL VGY Sbjct: 118 YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGY 177 Query: 286 GDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 G G ++W++KNSWG N+G +GYI MARNK N CGIA+ S+P++ Sbjct: 178 GIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >1S4V-A nrPDB Length = 229 Score = 306 bits (784), Expect = 8e-84, Method: Composition-based stats. Identities = 108/221 (48%), Positives = 140/221 (63%), Gaps = 9/221 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P SVDWR+KG VT VK QG CG+CWAFS + A+E ++KT KLVSLS Q LVDC T++ Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKY-RAATCSKYTELPYG 233 N+GCNGG M AF++I GI ++A+YPY+A D C + A + + +P Sbjct: 62 --NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDL-NGKE 292 E+ L +AVAN+ PVSV +DA F Y GV+ SC ++HGV +VGYG +G + Sbjct: 120 DENALLKAVANQ-PVSVAIDAGGSDFQFYSEGVFTG-SCGTELDHGVAIVGYGTTIDGTK 177 Query: 293 YWLVKNSWGHNFGEEGYIRMARN---KGNHCGIASFPSYPE 330 YW VKNSWG +GE+GYIRM R K CGIA SYP Sbjct: 178 YWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPI 218 >5JT8-A nrPDB Length = 333 Score = 304 bits (780), Expect = 3e-83, Method: Composition-based stats. Identities = 102/341 (29%), Positives = 166/341 (48%), Gaps = 18/341 (5%) Query: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60 MK L+ L A+ + +KK +GK Y+ EEA R +++ LK+V Sbjct: 1 MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVE 60 Query: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKS---NPNRILPD 117 HN G+ + +N DM+ +E +S + + + K N LP Sbjct: 61 EHN-----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQ 115 Query: 118 SVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGN 177 + DWR+K +T ++ QGSCG+CWAF+A G E+ ++ + + LS Q LVDC+ +Y Sbjct: 116 NFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDP 175 Query: 178 ----KGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPY- 232 GC G+ T AF+Y+I G+ + +YPY Q C D + + S Y +L Y Sbjct: 176 SYQCNGCGSGYSTEAFKYMI-RTGLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYH 234 Query: 233 -GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN-VNHGVLVVGYGDLNG 290 EDV+ + GPV + + + F +GV + +H V++VG+G + G Sbjct: 235 SSDEDVMYT-IQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQG 293 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 +YW+++NSWG +G GY + R N GI ++ +Y + Sbjct: 294 VDYWIIRNSWGTGWGNGGYGYVERG-HNSLGINNYVTYATL 333 >6BKI-A nrPDB Length = 215 Score = 304 bits (779), Expect = 3e-83, Method: Composition-based stats. Identities = 123/218 (56%), Positives = 156/218 (71%), Gaps = 4/218 (1%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +PDS+D+R+KG VT VK QG CG+CWAFS+ GALE QLK KTGKL++LS QNLVDC TE Sbjct: 1 VPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTEN 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 Y GC GG+MTTAFQY+ N GIDS+ +YPY D+ C Y++ +AA C Y E+P G Sbjct: 61 Y---GCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGN 117 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYGDLNGKEY 293 E LK AVA GP+SV +DA SF Y GVYY+ +C NVNH VLVVGYG G ++ Sbjct: 118 EKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKH 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 W++KNSWG ++G +GY +ARNK N CGI + S+P++ Sbjct: 178 WIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >1CQD-A nrPDB Length = 221 Score = 303 bits (775), Expect = 8e-83, Method: Composition-based stats. Identities = 110/220 (50%), Positives = 139/220 (63%), Gaps = 8/220 (3%) Query: 113 RILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCST 172 LPDS+DWRE G V VK QG CG+CWAFS V A+E ++ TG L+SLS Q LVDC+T Sbjct: 1 DDLPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTT 60 Query: 173 EKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPY 232 N GC GG+M AFQ+I++N GI+S+ +YPY+ D C + Y +P Sbjct: 61 ---ANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPS 117 Query: 233 GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKE 292 E L++AVAN+ PVSV +DA F LYRSG++ SC + NH + VVGYG N K+ Sbjct: 118 HNEQSLQKAVANQ-PVSVTMDAAGRDFQLYRSGIFTG-SCNISANHALTVVGYGTENDKD 175 Query: 293 YWLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYP 329 +W+VKNSWG N+GE GYIR RN N CGI F SYP Sbjct: 176 FWIVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYP 215 >2VHS-A nrPDB Length = 217 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 119/218 (54%), Positives = 156/218 (71%), Gaps = 4/218 (1%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CGA +AFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 2 PRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 60 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + ++P +E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY-EPSCTQNVNHGVLVVGYG-DLNGKEY 293 L +AVA GP+SV +DA H SF Y+ G+Y+ + ++NH +LVVGYG N ++Y Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 WLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >4YYR-A nrPDB Length = 222 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 105/219 (47%), Positives = 140/219 (63%), Gaps = 7/219 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR +G V ++ QG CG+CWAFS V +E K+ T +L SLS Q LVDC+T Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCAT-S 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 Y N GC+GG+MT A+ YII N GI S ++YPY A +C D + AT Y +P Sbjct: 60 YKNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E+ LK AVAN+ PVSV ++A +F LY+SGV+ SC ++H V+ +GYG N +Y Sbjct: 120 NENALKNAVANQ-PVSVTIEAGGRAFELYKSGVFVG-SCGTKLDHAVVAIGYGSENDVDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYP 329 WLV+NSWG N+GE GYI++ RN CGIA +YP Sbjct: 178 WLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYP 216 >3P5W-A nrPDB Length = 220 Score = 298 bits (764), Expect = 2e-81, Method: Composition-based stats. Identities = 105/218 (48%), Positives = 141/218 (64%), Gaps = 6/218 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LPD VDWR G V ++K QG CG+CWAFS + A+E K+ TG L+SLS Q LVDC + Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 +GC+GGFMT FQ+II+N GI+++A+YPY A + +C D + + + Y +PY Sbjct: 61 -NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L+ AVA + PVSV ++A +F Y SG++ P C V+H V +VGYG G +Y Sbjct: 120 NEWALQTAVAYQ-PVSVALEAAGYNFQHYSSGIFTGP-CGTAVDHAVTIVGYGTEGGIDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG--NHCGIASFPSYP 329 W+VKNSWG +GEEGY+R+ RN G CGIA SYP Sbjct: 178 WIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYP 215 >2FO5-A nrPDB Length = 262 Score = 296 bits (759), Expect = 7e-81, Method: Composition-based stats. Identities = 104/223 (46%), Positives = 136/223 (60%), Gaps = 12/223 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP SVDWR+KG VT VK QG CG+CWAFS V ++E ++TG LVSLS Q L+DC T Sbjct: 4 LPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTAD 63 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ----YDSKYRAATCSKYTEL 230 N GC GG M AF+YI +N G+ ++A+YPY+A C + + ++ Sbjct: 64 --NDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDV 121 Query: 231 PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGD-LN 289 P E+ L AVAN+ PVSV V+A +F Y GV+ C ++HGV VVGYG + Sbjct: 122 PANSEEDLARAVANQ-PVSVAVEASGKAFMFYSEGVFTG-ECGTELDHGVAVVGYGVAED 179 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARN---KGNHCGIASFPSYP 329 GK YW VKNSWG ++GE+GYIR+ ++ G CGIA SYP Sbjct: 180 GKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYP 222 >2PNS-A nrPDB Length = 208 Score = 293 bits (751), Expect = 5e-80, Method: Composition-based stats. Identities = 105/217 (48%), Positives = 140/217 (64%), Gaps = 12/217 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ +DWR+KG VT VK QG CG+CWAFS V +E+ +++TG L+SLS Q LVDC+ Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNK-- 58 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG A+QYIIDN GID++A+YPYKA+ C+ K Y +P+ Sbjct: 59 -KNHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCN 115 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E+ LK+AVA++ P V +DA F Y+SG++ P C +NHGV++VGY K+YW Sbjct: 116 ENALKKAVASQ-PSVVAIDASSKQFQHYKSGIFSGP-CGTKLNHGVVIVGY----WKDYW 169 Query: 295 LVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYPE 330 +V+NSWG +GE+GYIRM R G CGIA P YP Sbjct: 170 IVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPT 206 >1IWD-A nrPDB Length = 215 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 107/219 (48%), Positives = 138/219 (63%), Gaps = 9/219 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR KG V +K Q CG+CWAFSAV A+E+ K++TG+L+SLS Q LVDC T Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTAS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 GCNGG+M AFQYII N GID+ +YPY A+ C+ + R + + + + Sbjct: 61 ---HGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCK-PYRLRVVSINGFQRVTRNN 116 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E L+ AVA++ PVSV V+A F Y SG++ P C NHGV++VGYG +GK YW Sbjct: 117 ESALQSAVASQ-PVSVTVEAAGAPFQHYSSGIFTGP-CGTAQNHGVVIVGYGTQSGKNYW 174 Query: 295 LVKNSWGHNFGEEGYIRMARN---KGNHCGIASFPSYPE 330 +V+NSWG N+G +GYI M RN CGIA PSYP Sbjct: 175 IVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPT 213 >1AEC-A nrPDB Length = 218 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 102/218 (46%), Positives = 137/218 (62%), Gaps = 6/218 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR G V ++K QG CG CWAFSA+ +E K+ TG L+SLS Q L+DC + Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 +GCNGG++T FQ+II+N GI+++ +YPY A D +C D + T Y +PY Sbjct: 61 -NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L+ AV + PVSV +DA +F Y SG++ P C ++H V +VGYG G +Y Sbjct: 120 NEWALQTAVTYQ-PVSVALDAAGDAFKQYSSGIFTGP-CGTAIDHAVTIVGYGTEGGIDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH--CGIASFPSYP 329 W+VKNSW +GEEGY+R+ RN G CGIA+ PSYP Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >3BCN-A nrPDB Length = 209 Score = 290 bits (743), Expect = 4e-79, Method: Composition-based stats. Identities = 102/217 (47%), Positives = 134/217 (61%), Gaps = 12/217 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ VDWR KG V +K QG CG+CWAFS V +E+ +++TG L+SLS Q LVDCS Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSK-- 58 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG+ A+QYII N GID++A+YPYKA C+ K +P Sbjct: 59 -KNHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKK--VVRIDGCKGVPQCN 115 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E+ LK AVA++ P V +DA F Y+ G++ P C +NHGV++VGYG K+YW Sbjct: 116 ENALKNAVASQ-PSVVAIDASSKQFQHYKGGIFTGP-CGTKLNHGVVIVGYG----KDYW 169 Query: 295 LVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYPE 330 +V+NSWG ++GE+GY RM R G CGIA P YP Sbjct: 170 IVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPT 206 >4YYW-A nrPDB Length = 220 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 99/219 (45%), Positives = 133/219 (60%), Gaps = 7/219 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR KG V ++ QG CG+CW FS +E +K+ T L SLS Q L+DC+ Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCA-PS 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYR-AATCSKYTELPYG 233 Y + GC GG+M A+ YII ++GI S++ YPY A C AT S Y ++P Sbjct: 60 YKDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPAD 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 ED LK+AVAN+ PVSV +DA + Y SGV+ SC +H V+VVGYG +G Y Sbjct: 120 NEDALKKAVANQ-PVSVAIDASSAAVKEYSSGVFVG-SCGVANDHAVVVVGYGTESGVNY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNK---GNHCGIASFPSYP 329 WLV+NSWG +GEEGY+++ R+ CGIA +YP Sbjct: 178 WLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYP 216 >1O0E-A nrPDB Length = 208 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 106/217 (48%), Positives = 136/217 (62%), Gaps = 12/217 (5%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+ +DWR+KG VT VK QGSCG+CWAFS V +E+ +++TG L+SLS Q LVDC Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDK-- 58 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 N GC GG A+QYII+N GID+ A+YPYKA+ CQ SK + Y +P+ Sbjct: 59 -KNHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCN 115 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E LK+AVA + P +V +DA F Y SG++ P C +NHGV +VGY YW Sbjct: 116 EXALKQAVAVQ-PSTVAIDASSAQFQQYSSGIFSGP-CGTKLNHGVTIVGY----QANYW 169 Query: 295 LVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSYPE 330 +V+NSWG +GE+GYIRM R G CGIA P YP Sbjct: 170 IVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPT 206 >3F75-A nrPDB Length = 224 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 99/222 (44%), Positives = 141/222 (63%), Gaps = 7/222 (3%) Query: 114 ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTE 173 LP VDWR +GCVT VK Q CG+CWAFS GALE KTGKLVSLS Q L+DCS Sbjct: 6 ELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRA 65 Query: 174 KYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYG 233 + GN+ C+GG M AFQY++D+ GI S+ +YPY A D++C+ S + + ++P Sbjct: 66 E-GNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRR 124 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG--DLNGK 291 E +K A+A K PVS+ ++A F Y GV+ + SC +++HGVL+VGYG + K Sbjct: 125 SEAAMKAALA-KSPVSIAIEADQMPFQFYHEGVF-DASCGTDLDHGVLLVGYGTDKESKK 182 Query: 292 EYWLVKNSWGHNFGEEGYIRMA--RNKGNHCGIASFPSYPEI 331 ++W++KNSWG +G +GY+ MA + + CG+ S+P + Sbjct: 183 DFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >1NB3-A nrPDB Length = 220 Score = 287 bits (734), Expect = 5e-78, Method: Composition-based stats. Identities = 99/220 (45%), Positives = 131/220 (59%), Gaps = 7/220 (3%) Query: 115 LPDSVDWREKG-CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTE 173 P S+DWR+KG V+ VK QGSCG+CW FS GALE+ + + TGK++SL+ Q LVDC+ + Sbjct: 1 YPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCA-Q 59 Query: 174 KYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYG 233 + N GC GG + AF+YI NKGI + +YPYK D C++ A + Sbjct: 60 NFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT---QNVNHGVLVVGYGDLNG 290 E+ + EAVA PVS + + F +YR G+Y SC VNH VL VGYG+ NG Sbjct: 120 DEEAMVEAVALYNPVSFAFEVTN-DFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENG 178 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPE 330 YW+VKNSWG +G GY + R K N CG+A+ SYP Sbjct: 179 IPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 217 >2ACT-A nrPDB Length = 220 Score = 285 bits (730), Expect = 2e-77, Method: Composition-based stats. Identities = 98/218 (44%), Positives = 136/218 (62%), Gaps = 6/218 (2%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP VDWR G V ++K QG CG CWAFSA+ +E K+ +G L+SLS Q L+DC + Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYD-SKYRAATCSKYTELPYG 233 +GC+GG++T FQ+II++ GI+++ +YPY A D C + T Y +PY Sbjct: 61 -NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYN 119 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L+ AV + PVSV +DA +F Y SG++ P C V+H +++VGYG G +Y Sbjct: 120 NEWALQTAVTYQ-PVSVALDAAGDAFKQYASGIFTGP-CGTAVDHAIVIVGYGTEGGVDY 177 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH--CGIASFPSYP 329 W+VKNSW +GEEGY+R+ RN G CGIA+ PSYP Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >1YAL-A nrPDB Length = 218 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 96/219 (43%), Positives = 129/219 (58%), Gaps = 10/219 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 P S+DWR KG VT VK QG+CG+CWAFS + +E K+ TG L+ LS Q LVDC Sbjct: 1 YPQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDKHS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQY-DSKYRAATCSKYTELPYG 233 Y GC GG+ TT+ QY+ +N G+ + YPY+A KC+ D + Y +P Sbjct: 61 Y---GCKGGYQTTSLQYVANN-GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E A+AN+ P+SV V+A F LY+SGV+ P C ++H V VGYG +GK Y Sbjct: 117 CETSFLGALANQ-PLSVLVEAGGKPFQLYKSGVFDGP-CGTKLDHAVTAVGYGTSDGKNY 174 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 ++KNSWG N+GE+GY+R+ R GN CG+ YP Sbjct: 175 IIIKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >2BDZ-A nrPDB Length = 214 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 96/220 (43%), Positives = 131/220 (59%), Gaps = 14/220 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 P+S+DWREKG VT VK Q CG+CWAFS V +E K+ TG+L+SLS Q L+DC Sbjct: 1 YPESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCERRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ-YDSKYRAATCSKYTELPYG 233 GC+GG+ TT+ QY++DN G+ ++ YPY+ +C+ D K + Y +P Sbjct: 61 ---HGCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPAN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L +A+AN+ PVSV D+R F Y+ G+Y P C N +H V VGYG K Y Sbjct: 117 DEISLIQAIANQ-PVSVVTDSRGRGFQFYKGGIYEGP-CGTNTDHAVTAVGYG----KTY 170 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYPE 330 L+KNSWG N+GE+GYIR+ R G CG+ + +P Sbjct: 171 LLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPI 210 >1PPO-A nrPDB Length = 216 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 97/220 (44%), Positives = 126/220 (57%), Gaps = 10/220 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR+KG VT V++QGSCG+CWAFSAV +E K++TGKLV LS Q LVDC Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYG 233 GC GG+ A +Y+ N GI + YPYKA C+ S + Sbjct: 61 ---HGCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L A+A + PVSV V+++ F LY+ G++ P C V+H V VGYG GK Y Sbjct: 117 NEGNLLNAIAKQ-PVSVVVESKGRPFQLYKGGIFEGP-CGTKVDHAVTAVGYGKSGGKGY 174 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPE 330 L+KNSWG +GE+GYIR+ R GN CG+ YP Sbjct: 175 ILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 214 >1XKG-A nrPDB Length = 312 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 86/304 (28%), Positives = 146/304 (48%), Gaps = 28/304 (9%) Query: 22 PTLDHHWHLWKKTYGKQYKE-KNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHL 80 P+ + +KK + K Y ++EEA R+ E ++K+V S +NHL Sbjct: 2 PSSIKTFEEYKKAFNKSYATFEDEEAARKNFLE-SVKYV-----------QSNGGAINHL 49 Query: 81 GDMTSEEV-----MSLMSSLRVPSQWQRNI-TYKSNPNRILPDSVDWREKGCVTEVKYQG 134 D++ +E MS + + +Q+ N T + N P +D R+ VT ++ QG Sbjct: 50 SDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQG 109 Query: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194 CG+ WAFS V A E+ + + L+ Q LVDC+++ GC+G + +YI Sbjct: 110 GCGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCASQ----HGCHGDTIPRGIEYIQH 165 Query: 195 NKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVAN-KGPVSVGVD 253 N G+ ++ Y Y A +Q C+ + R S Y ++ + ++EA+A ++V + Sbjct: 166 N-GVVQESYYRYVAREQSCRRPNAQRFG-ISNYCQIYPPNANKIREALAQTHSAIAVIIG 223 Query: 254 ARHPSFFLYRSG--VYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311 + F + G + + Q H V +VGY + G +YW+V+NSW N+G+ GY Sbjct: 224 IKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGY 283 Query: 312 MARN 315 A N Sbjct: 284 FAAN 287 >4YYQ-A nrPDB Length = 217 Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats. Identities = 103/218 (47%), Positives = 145/218 (66%), Gaps = 7/218 (3%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP++VDWR KG V ++ QG CG+CWAFSAV A+E+ K+ TG+L+SLS Q L+DC+ + Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCA-QS 59 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 Y N GC GG++ AF+YII N+GI S ++YPY +C+ AT Y +P Sbjct: 60 YKNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCRT-GLASIATIDSYQYVPSNN 118 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYW 294 E+ LK AVAN+ PVSV V+A +F LY+SGV+ SC ++H V+++GYG NG +YW Sbjct: 119 ENALKNAVANQ-PVSVAVEAAGRAFQLYKSGVFTG-SCGVAIDHAVVLIGYGKYNGVDYW 176 Query: 295 LVKNSWGHNFGEEGYIRMARN---KGNHCGIASFPSYP 329 L++NSWG N+GE+GY+++ RN CG+A YP Sbjct: 177 LLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYP 214 >6MIS-A nrPDB Length = 215 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 93/221 (42%), Positives = 141/221 (63%), Gaps = 11/221 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P S+DWR+ G VT VK QG CG+CWAF+++ +E+ K+K G LVSLS Q ++DC+ Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAV-- 58 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 + GC GG++ A+ +II NKG+ S A YPYKA C+ + +A ++YT + Sbjct: 59 --SYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNN 116 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYG-DLNGKEY 293 E + AV+N+ P++ +DA +F Y+ GV+ P C +NH ++++GYG D +GK++ Sbjct: 117 ERNMMYAVSNQ-PIAAALDASG-NFQHYKRGVFTGP-CGTRLNHAIVIIGYGQDSSGKKF 173 Query: 294 WLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYPEI 331 W+V+NSWG +GE GYIR+AR+ CGIA P YP + Sbjct: 174 WIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >5A24-A nrPDB Length = 222 Score = 266 bits (681), Expect = 7e-72, Method: Composition-based stats. Identities = 103/224 (45%), Positives = 133/224 (59%), Gaps = 11/224 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P +VDWR G VT VK Q CG CWAFSAV A+E ++KTG L SLS + +VDC T Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNG 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA---MDQKCQYDSKYRAATCSKYTELP 231 +KGCNGG AFQY+++N+GID+++ YPY A C S AA+ + Y ++P Sbjct: 61 -NDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVP 119 Query: 232 YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGD--LN 289 E + A P+SV +DA PSF Y SG+Y P C N++H V VVGYG + Sbjct: 120 ANNEQA-LQQAAATQPISVAIDASDPSFQSYSSGIYSGP-CNTNLDHAVTVVGYGTDPNS 177 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYPE 330 G YW+VKNSWG ++G+EGYI M CGIA SYP Sbjct: 178 GNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >2CIO-A nrPDB Length = 212 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 93/219 (42%), Positives = 126/219 (57%), Gaps = 14/219 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P+ VDWR+KG VT VK QGSCG+CWAFSAV +E +K++TG L S Q L+DC Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYR-AATCSKYTELPYG 233 Y GCNGG+ +A Q ++ GI +YPY+ + + C+ K AA ++ Sbjct: 61 Y---GCNGGYPWSALQ-LVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPY 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L ++AN+ PVSV ++A F LYR G++ P C V+H V VGYG Y Sbjct: 117 NEGALLYSIANQ-PVSVVLEAAGKDFQLYRGGIFVGP-CGNKVDHAVAAVGYGP----NY 170 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYP 329 L+KNSWG +GE GYIR+ R GN CG+ + YP Sbjct: 171 ILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYP 209 >1GEC-E nrPDB Length = 216 Score = 259 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 97/220 (44%), Positives = 124/220 (56%), Gaps = 10/220 (4%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 LP+SVDWR KG VT VK+QG C +CWAFS V +E K+KTG LV LS Q LVDC + Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCDLQS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYG 233 Y GCN G+ +T+ QY+ N GI A YPY A Q C+ + + + Sbjct: 61 Y---GCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L A+A++ PVSV V++ F Y+ G++ SC V+H V VGYG GK Y Sbjct: 117 NEGSLLNAIAHQ-PVSVVVESAGRDFQNYKGGIFEG-SCGTKVDHAVTAVGYGKSGGKGY 174 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPE 330 L+KNSWG +GE GYIR+ R GN CG+ YP Sbjct: 175 ILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPI 214 >2B1M-A nrPDB Length = 246 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 97/228 (42%), Positives = 135/228 (59%), Gaps = 18/228 (7%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P+S DW +KG +T+VK+QG CG+ WAFSA GA+EA + TG LVSLS Q L+DC E Sbjct: 3 PESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDES- 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKY-------T 228 +GC G+ +F++++ + GI S+A YPYKA D KC+ + T Y Sbjct: 62 --EGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNE 119 Query: 229 ELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN--VNHGVLVVGYG 286 E L+ V + P+SV +DA+ F Y G+Y +C+ +NH VL+VGYG Sbjct: 120 STESEAESSLQSFVLEQ-PISVSIDAK--DFHFYSGGIYDGGNCSSPYGINHFVLIVGYG 176 Query: 287 DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPEI 331 +G +YW+ KNSWG ++G +GYIR+ RN GN CG+ F SYP I Sbjct: 177 SEDGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPII 224 >1ICF-A nrPDB Length = 175 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 99/175 (56%), Positives = 130/175 (74%), Gaps = 3/175 (1%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 2 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 60 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLN 289 L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >3U8E-A nrPDB Length = 222 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 97/223 (43%), Positives = 129/223 (57%), Gaps = 14/223 (6%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P S+DWR+KG VT VK QG+CG CWAF A GA+E + TG+L+S+S Q +VDC T Sbjct: 2 PASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXXX 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 GG AF+++I N GI SDA+YPY +D C + K AA YT +P Sbjct: 62 XXX---GGDADDAFRWVITNGGIASDANYPYTGVDGTCDLN-KPIAARIDGYTNVP-NSS 116 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRS-GVYYEPSCTQN---VNHGVLVVGYGDLN-G 290 L +AVA + PVSV + SF LY G++ SC+ + V+H VL+VGYG Sbjct: 117 SALLDAVAKQ-PVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTN 175 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKG---NHCGIASFPSYPE 330 +YW+VKNSWG +G +GYI + RN C I ++ SYP Sbjct: 176 ADYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPT 218 >1MIR-A nrPDB Length = 322 Score = 247 bits (630), Expect = 7e-66, Method: Composition-based stats. Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 52/310 (16%) Query: 54 KNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNR 113 + ++ N G + Y++ +++L + +++ ++P + + + + N Sbjct: 12 DMINYINKQNTTWQAGRNFYNVDISYLKKLCG----TVLGGPKLPER----VGFSEDIN- 62 Query: 114 ILPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGK--LVSLSAQNL 167 LP+S D W + +++ QGSCG+ WAF AV A+ ++ + T V +SA++L Sbjct: 63 -LPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 121 Query: 168 VDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQ------ 214 + C + G+ GCNGG+ + A+ + KG+ S Y PY + Sbjct: 122 LTCCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARP 179 Query: 215 ------------------YDSKYRAATCSKYTELPYGR-EDVLKEAVANKGPVSVGVDAR 255 Y + Y+ YT E + + GPV G Sbjct: 180 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVE-GAFTV 238 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 239 FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRG 298 Query: 316 KGNHCGIASF 325 + NHCGI S Sbjct: 299 E-NHCGIESE 307 >3PBH-A nrPDB Length = 317 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 83/308 (26%), Positives = 134/308 (43%), Gaps = 52/308 (16%) Query: 56 LKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRIL 115 + +V N G + Y++ M++L + + + + P + + L Sbjct: 15 VNYVNKRNTTWQAGHNFYNVDMSYLKRLCG----TFLGGPKPPQRVMFTE------DLKL 64 Query: 116 PDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLVD 169 P S D W + + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+ Sbjct: 65 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 124 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRAA 222 C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 125 CCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 182 Query: 223 T-------CSKYTELPY------------------GREDVLKEAVANKGPVSVGVDARHP 257 T CSK E Y E + + GPV G + + Sbjct: 183 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE-GAFSVYS 241 Query: 258 SFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKG 317 F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R + Sbjct: 242 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ- 300 Query: 318 NHCGIASF 325 +HCGI S Sbjct: 301 DHCGIESE 308 >3IOQ-A nrPDB Length = 213 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 90/220 (40%), Positives = 127/220 (57%), Gaps = 14/220 (6%) Query: 115 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 174 +P S+DWR+KG VT V+ QG CG+CW FS+V A+E K+ TG+L+SLS Q L+DC Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCERRS 60 Query: 175 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYG 233 Y GC GGF A QY+ N GI YPY+ + ++C+ K +P Sbjct: 61 Y---GCRGGFPLYALQYVA-NSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRN 116 Query: 234 REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEY 293 E L + +A + PVS+ V+A+ +F YR G++ P C +++H V VGYG+ +Y Sbjct: 117 NEQALIQRIAIQ-PVSIVVEAKGRAFQNYRGGIFAGP-CGTSIDHAVAAVGYGN----DY 170 Query: 294 WLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYPE 330 L+KNSWG +GE GYIR+ R GN CG+ S +P Sbjct: 171 ILIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPT 210 >6EXO-A nrPDB Length = 215 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 87/210 (41%), Positives = 126/210 (60%), Gaps = 13/210 (6%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P +VDWREKG VT VK QG CG+CWAFS +G +E Q ++ LVSLS Q LV C T + Sbjct: 2 PAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDF 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKG--IDSDASYPYK---AMDQKCQYDSKYRAATCSKYTEL 230 GC GG M AF +I+++ G + ++ASYPY +CQ + A + + +L Sbjct: 62 ---GCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDL 118 Query: 231 PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNG 290 P ED + +A GP+++ VDA SF Y G+ + ++ ++HGVL+VGY D + Sbjct: 119 PQ-DEDAIAAYLAENGPLAIAVDAT--SFMDYNGGILTSCT-SEQLDHGVLLVGYNDASN 174 Query: 291 KEYWLVKNSWGHNFGEEGYIRMARNKGNHC 320 YW++KNSW + +GE+GYIR+ + N C Sbjct: 175 PPYWIIKNSWSNMWGEDGYIRIEKGT-NQC 203 >3PDF-A nrPDB Length = 441 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 73/230 (31%), Positives = 113/230 (49%), Gaps = 22/230 (9%) Query: 114 ILPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLV 168 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 206 FLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVV 265 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYT 228 CS +GC GGF + G+ +A +PY D C+ S+Y Sbjct: 266 SCSQYA---QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 322 Query: 229 ELPY----GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN------VNH 278 + E ++K + + GP++V + + F Y+ G+Y+ NH Sbjct: 323 YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNH 381 Query: 279 GVLVVGYGD--LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFP 326 VL+VGYG +G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 382 AVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESIA 430 >3BPF-A nrPDB Length = 241 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 80/229 (34%), Positives = 122/229 (53%), Gaps = 22/229 (9%) Query: 117 DSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYG 176 + DWR VT VK Q +CG+CWAFS++G++E+Q ++ KL++LS Q LVDCS + Sbjct: 20 AAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCS---FK 76 Query: 177 NKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQK-CQYDSKYRAATCSKYTELPYGRE 235 N GCNGG + AF+ +I+ GI D YPY + C D Y +P + Sbjct: 77 NYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP---D 133 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKE--- 292 + LKEA+ GP+S+ V A F Y+ G++ + C +NH V++VG+G Sbjct: 134 NKLKEALRFLGPISISV-AVSDDFAFYKEGIF-DGECGDQLNHAVMLVGFGMKEIVNPLT 191 Query: 293 -------YWLVKNSWGHNFGEEGYIRMARNKGN---HCGIASFPSYPEI 331 Y+++KNSWG +GE G+I + ++ CG+ + P I Sbjct: 192 KKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >4PI3-A nrPDB Length = 216 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 90/218 (41%), Positives = 124/218 (56%), Gaps = 15/218 (6%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P +VDWR +G VT VK QG CG+CWAFSA+G +E Q L L +LS Q LV C Sbjct: 3 PAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKT-- 60 Query: 176 GNKGCNGGFMTTAFQYII--DNKGIDSDASYPY---KAMDQKCQYDSKYRAATCSKYTEL 230 + GC+GG M AF++I+ +N + ++ SYPY + + C AT + + EL Sbjct: 61 -DSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL 119 Query: 231 PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLN 289 P E + +A GPV+V VDA S+ Y GV SC ++ ++HGVL+VGY D Sbjct: 120 PQ-DEAQIAAWLAVNGPVAVAVDA--SSWMTYTGGVMT--SCVSEQLDHGVLLVGYNDSA 174 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327 YW++KNSW +GEEGYIR+A+ N C + S Sbjct: 175 AVPYWIIKNSWTTQWGEEGYIRIAKGS-NQCLVKEEAS 211 >1JQP-A nrPDB Length = 438 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 74/230 (32%), Positives = 112/230 (48%), Gaps = 22/230 (9%) Query: 114 ILPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLV 168 LP+S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 205 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 264 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSK-- 226 CS +GC+GGF + G+ + +PY A D C+ S+ Sbjct: 265 SCSPYA---QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYY 321 Query: 227 --YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN------VNH 278 E ++K + GP++V + H F Y SG+Y+ + NH Sbjct: 322 YVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNH 380 Query: 279 GVLVVGYGDL--NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFP 326 VL+VGYG G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 381 AVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESIA 429 >3BPM-A nrPDB Length = 243 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 85/239 (35%), Positives = 126/239 (52%), Gaps = 22/239 (9%) Query: 107 YKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQN 166 YK ++ + DWR G VT VK Q CG+CWAFS+VG++E+Q ++ L S Q Sbjct: 12 YKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQE 71 Query: 167 LVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA-MDQKCQYDSKYRAATCS 225 LVDCS N GC GG++T AF +ID G+ S YPY + + + C T Sbjct: 72 LVDCSV---KNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIK 128 Query: 226 KYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGY 285 Y +P +D KEA+ GP+S+ + A F YR G +Y+ C NH V++VGY Sbjct: 129 SYVSIP---DDKFKEALRYLGPISISI-AASDDFAFYRGG-FYDGECGAAPNHAVILVGY 183 Query: 286 G--DLNGKE--------YWLVKNSWGHNFGEEGYIRMARNKGNH---CGIASFPSYPEI 331 G D+ ++ Y+++KNSWG ++GE GYI + ++ + C I + P + Sbjct: 184 GMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >1M6D-A nrPDB Length = 214 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 79/213 (37%), Positives = 116/213 (54%), Gaps = 6/213 (2%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P DWR KG VT+VK QG CG+CWAFS G +E Q L G L+SLS Q L+DC Sbjct: 2 PPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKM-- 59 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 235 +K C GG + A+ I + G++++ Y Y+ Q CQ+ ++ EL E Sbjct: 60 -DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQ-NE 117 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYW 294 L +A +GP+SV ++A F+ + P C+ ++H VL+VGYG + +W Sbjct: 118 QKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFW 177 Query: 295 LVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327 +KNSWG ++GE+GY + R G CG+ + S Sbjct: 178 AIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMAS 209 >5VCN-A nrPDB Length = 222 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 65/213 (30%), Positives = 107/213 (50%), Gaps = 9/213 (4%) Query: 106 TYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQ 165 T + N P +D R+ VT ++ QG CG+CWAFS V A E+ + + L+ Q Sbjct: 1 TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQ 60 Query: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCS 225 LVDC+++ GC+G + +YI N G+ ++ Y Y A +Q C+ + R S Sbjct: 61 ELVDCASQ----HGCHGDTIPRGIEYIQHN-GVVQESYYRYVAREQSCRRPNAQRFG-IS 114 Query: 226 KYTELPYGREDVLKEAVAN-KGPVSVGVDARHPSFFLYRSG--VYYEPSCTQNVNHGVLV 282 Y ++ + ++EA+A ++V + + F + G + + Q H V + Sbjct: 115 NYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNI 174 Query: 283 VGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 VGY + G +YW+V+NSW N+G+ GY A N Sbjct: 175 VGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAAN 207 >5VPK-A nrPDB Length = 223 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 62/209 (29%), Positives = 100/209 (47%), Gaps = 9/209 (4%) Query: 112 NRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCS 171 + +P +D R VT ++ QG CG+CWAFS V A E+ + LS Q LVDC+ Sbjct: 8 SVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCA 67 Query: 172 TEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELP 231 ++ GC+G + +YI N G+ + SYPY A +Q+C+ + S Y ++ Sbjct: 68 SQ----HGCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQQCRRPNSQHYG-ISNYCQIY 121 Query: 232 YGREDVLKEAVANKG-PVSVGVDARH-PSFFLYRS-GVYYEPSCTQNVNHGVLVVGYGDL 288 ++EA+ ++V + + +F Y + + Q H V +VGYG Sbjct: 122 PPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGST 181 Query: 289 NGKEYWLVKNSWGHNFGEEGYIRMARNKG 317 G +YW+V+NSW +G+ GY Sbjct: 182 QGVDYWIVRNSWDTTWGDSGYGYFQAGNN 210 >1CPJ-A nrPDB Length = 260 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 72/252 (28%), Positives = 112/252 (44%), Gaps = 42/252 (16%) Query: 112 NRILPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGK--LVSLSAQ 165 + LP+S D W + +++ QGSCG+CWAF AV A+ ++ + T V +SA+ Sbjct: 4 DINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 63 Query: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQ---- 214 +L+ C + G+ GCNGG+ + A+ + KG+ S Y PY + Sbjct: 64 DLLTCCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGA 121 Query: 215 --------------------YDSKYRAATCSKYTELPYGR-EDVLKEAVANKGPVSVGVD 253 Y + Y+ YT E + + GPV G Sbjct: 122 RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVE-GAF 180 Query: 254 ARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMA 313 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ Sbjct: 181 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 314 RNKGNHCGIASF 325 R + NHCGI S Sbjct: 241 RGE-NHCGIESE 251 >4I05-A nrPDB Length = 285 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 70/266 (26%), Positives = 115/266 (43%), Gaps = 44/266 (16%) Query: 99 SQWQRNITYKSNPNRILPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKL 154 + +R ++ N +P S D R+K + ++ Q CG+CWAF AV A+ + + Sbjct: 18 RRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCI 77 Query: 155 KTG--KLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA-------SYP 205 ++G + V LSA +L+ C + GC GG + A+ Y + +GI + + P Sbjct: 78 QSGGKQNVELSAVDLLSCC--ESCGLGCEGGILGPAWDYWVK-EGIVTGSSKENHAGCEP 134 Query: 206 YKAMDQKCQYDSKYR------------AATCSKYTELPY--------------GREDVLK 239 Y + KY TC K + PY E ++ Sbjct: 135 YPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQ 194 Query: 240 EAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNS 299 + + GPV G + F Y+SG+Y + H + ++G+G N YWL+ NS Sbjct: 195 KEIMKYGPVEAGF-TVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANS 253 Query: 300 WGHNFGEEGYIRMARNKGNHCGIASF 325 W ++GE GY R+ R + + C I S Sbjct: 254 WNEDWGENGYFRIVRGR-DECSIESE 278 >4HWY-A nrPDB Length = 340 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 69/254 (27%), Positives = 100/254 (39%), Gaps = 36/254 (14%) Query: 108 KSNPNRILPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG-KLVSL 162 + LP S D W + ++ Q +CG+CWA +A A+ + G + V + Sbjct: 87 EEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHI 146 Query: 163 SAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAA 222 SA +L+ C ++ GCNGG A+ Y + G+ SD PY SK Sbjct: 147 SAGDLLACCSD--CGDGCNGGDPDRAWAYF-SSTGLVSDYCQPYPFPHCSHHSKSKNGYP 203 Query: 223 TCSKYT-ELPYGR-----------------------EDVLKEAVANKGPVSVGVDARHPS 258 CS++ + P ED + +GP V D + Sbjct: 204 PCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDV-YED 262 Query: 259 FFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGN 318 F Y SGVY+ S H V +VG+G NG YW + NSW +G +GY + R Sbjct: 263 FIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSS- 321 Query: 319 HCGIA--SFPSYPE 330 CGI P Sbjct: 322 ECGIEDGGSAGIPL 335 >3CBK-A nrPDB Length = 266 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 75/250 (30%), Positives = 113/250 (45%), Gaps = 42/250 (16%) Query: 114 ILPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNL 167 LP S D W + + E++ QGSCG+ WAF AV A+ ++ + T VS+ SA++L Sbjct: 6 KLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDL 65 Query: 168 VDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYR 220 + C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 66 LTCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEAHVNGARP 123 Query: 221 AAT-------CSKYTELPY------------------GREDVLKEAVANKGPVSVGVDAR 255 T CSK E Y E + + GPV G + Sbjct: 124 PCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE-GAFSV 182 Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315 + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 183 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 242 Query: 316 KGNHCGIASF 325 + +HCGI S Sbjct: 243 Q-DHCGIESE 251 >4I04-A nrPDB Length = 323 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 74/313 (23%), Positives = 126/313 (40%), Gaps = 56/313 (17%) Query: 56 LKFVMLH-NLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVP---SQWQRNITYKSNP 111 + ++ H N N + ++ M + R + +R ++ Sbjct: 17 ISYINEHPNAGWRAEKS------NRFH--SLDDARIQMGARREEPDLRRTRRPTVDHNDW 68 Query: 112 NRILPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQ 165 N +P S D R+K + ++ Q CG+ WAF AV A+ + +++G + V LSA Sbjct: 69 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAV 128 Query: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA-------SYPYKAMDQKCQYDSK 218 +L+ C + GC GG + A+ Y + +GI + + PY + K Sbjct: 129 DLLSCC--ESCGLGCEGGILGPAWDYWVK-EGIVTGSSKENHAGCEPYPFPKCEHHTKGK 185 Query: 219 YR------------AATCSKYTELPY--------------GREDVLKEAVANKGPVSVGV 252 Y TC K + PY E +++ + GPV G Sbjct: 186 YPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGF 245 Query: 253 DARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 + F Y+SG+Y + H + ++G+G N YWL+ NSW ++GE GY R+ Sbjct: 246 -TVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRI 304 Query: 313 ARNKGNHCGIASF 325 R + + C I S Sbjct: 305 VRGR-DECSIESE 316 >5OGQ-A nrPDB Length = 254 Score = 204 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 44/252 (17%) Query: 113 RILPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQN 166 +P S D R+K + ++ Q CG+CWAF AV A+ + +++G + V LSA + Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 167 LVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA-------SYPYKAMDQKCQYDSKY 219 L+ C + GC GG + A+ Y + +GI + + PY + KY Sbjct: 61 LLSCC--ESCGLGCEGGILGPAWDYWVK-EGIVTGSSKENHAGCEPYPFPKCEHHTKGKY 117 Query: 220 R------------AATCSKYTELPY--------------GREDVLKEAVANKGPVSVGVD 253 TC K + PY E +++ + GPV G Sbjct: 118 PPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGF- 176 Query: 254 ARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMA 313 + F Y+SG+Y + H + ++G+G N YWL+ NSW ++GE GY R+ Sbjct: 177 TVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIV 236 Query: 314 RNKGNHCGIASF 325 R + + C I S Sbjct: 237 RGR-DECSIESE 247 >2DCB-A nrPDB Length = 256 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 73/249 (29%), Positives = 113/249 (45%), Gaps = 42/249 (16%) Query: 115 LPDSVD----WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGK--LVSLSAQNLV 168 LP+S D W + E++ QGSCG+CWAF AV A+ ++ + + V +SA++++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221 C + G+ NGGF + A+ + KG+ S Y PY + + Sbjct: 61 TCCGGECGDGC-NGGFPSGAWNFWTK-KGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPP 118 Query: 222 AT-------CSKYTELPY------------------GREDVLKEAVANKGPVSVGVDARH 256 T CSK E Y E + + GPV G + + Sbjct: 119 CTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVE-GAFSVY 177 Query: 257 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 316 F LY+SGVY S H + ++G+G NG YWLV NSW ++G+ G+ ++ R + Sbjct: 178 SDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQ 237 Query: 317 GNHCGIASF 325 +HCGI S Sbjct: 238 -DHCGIESE 245 >5FPW-A nrPDB Length = 321 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 114/283 (40%), Gaps = 41/283 (14%) Query: 82 DMTSEEVMSLMSSLRVPSQWQRNITY-KSNPNRILPDSVD----WREKGCVTEVKYQGSC 136 ++T E L + + + + + LP+S D W + E+ Q +C Sbjct: 41 NITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTELPESFDSAEKWPNCPTIREIADQSAC 100 Query: 137 GACWAFSAVGALEAQLKLKTG-KLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195 A WA S + + G + + +SA +L+ C + G GGF A++Y ++ Sbjct: 101 RASWAVSTASVISDRYCTVGGVQQLRISAAHLLSCCKQCGGGC--KGGFPGFAWRYYVE- 157 Query: 196 KGIDSDASYPYKAMDQKCQ-------------YDSKYRAATCSKYTELP----------- 231 GI S PY + + +D+ ATC+ +P Sbjct: 158 YGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDTPKCQATCTD-KSIPLVKYRGSATYL 216 Query: 232 --YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLN 289 +G ED +E N GP V V + F Y+SGVY V VVG+G LN Sbjct: 217 LLHGEEDYKRELYFN-GPF-VAVFYVYTDLFAYKSGVYRHVDGDFLGGTAVKVVGWGKLN 274 Query: 290 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIA--SFPSYPE 330 G YW V N+W ++G +GY+ + R N C I F PE Sbjct: 275 GTPYWKVANTWDTDWGMDGYLLILRG-NNECNIEHLGFAGTPE 316 >1DEU-A nrPDB Length = 277 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 36/224 (16%) Query: 115 LPDSVDWREKGCV---TEVKYQ---GSCGACWAFSAVGALEAQLKLK-TGKLVS--LSAQ 165 LP S DWR V + + Q CG+CWA ++ A+ ++ +K G S LS Q Sbjct: 36 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 95 Query: 166 NLVDCSTEKYGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATC 224 N++DC GN G C GG + + Y GI + Y+A DQ+C D + TC Sbjct: 96 NVIDC-----GNAGSCEGGNDLSVWDY-AHQHGIPDETCNNYQAKDQEC--DKFNQCGTC 147 Query: 225 SKYTELP----------------YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268 +++ E GRE ++ E AN GP+S G+ A Y G+Y Sbjct: 148 NEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATER-LANYTGGIYA 205 Query: 269 EPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 E T +NH V V G+G +G EYW+V+NSWG +GE G++R+ Sbjct: 206 EYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 249 >4OEL-A nrPDB Length = 370 Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 47/166 (28%), Positives = 80/166 (48%), Gaps = 13/166 (7%) Query: 115 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLVD 169 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 207 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 266 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 229 CS +GC GGF + G+ +A +PY D C+ S+Y Sbjct: 267 CSQYA---QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHY 323 Query: 230 L----PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271 + E ++K + + GP++V + + F Y+ G+Y+ Sbjct: 324 VGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTG 368 >5I4H-A nrPDB Length = 106 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 67/105 (63%), Positives = 81/105 (77%), Gaps = 1/105 (0%) Query: 116 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 175 P SVDWREKG VT VK QG CG+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 3 PRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 61 Query: 176 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYR 220 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 106 >1EF7-A nrPDB Length = 242 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 36/224 (16%) Query: 115 LPDSVDWREKGCV---TEVKYQ---GSCGACWAFSAVGALEAQLKLK-TGKLVS--LSAQ 165 LP S DWR V + + Q CG+CWA ++ A+ ++ +K G S LS Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 166 NLVDCSTEKYGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATC 224 N++DC GN G C GG + + Y GI + Y+A DQ+C D + TC Sbjct: 61 NVIDC-----GNAGSCEGGNDLSVWDY-AHQHGIPDETCNNYQAKDQEC--DKFNQCGTC 112 Query: 225 SKYTELP----------------YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268 +++ E GRE ++ E AN GP+S G+ A Y G+Y Sbjct: 113 NEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATER-LANYTGGIYA 170 Query: 269 EPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312 E T +NH V V G+G +G EYW+V+NSWG +GE G++R+ Sbjct: 171 EYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 214 >4CDF-B nrPDB Length = 166 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 47/166 (28%), Positives = 80/166 (48%), Gaps = 13/166 (7%) Query: 115 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLVD 169 LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 3 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 62 Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 229 CS +GC GGF + G+ +A +PY D C+ S+Y Sbjct: 63 CSQYA---QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHY 119 Query: 230 L----PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271 + E ++K + + GP++V + + F Y+ G+Y+ Sbjct: 120 VGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTG 164 >1CSB-B nrPDB Length = 205 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 56/199 (28%), Positives = 85/199 (42%), Gaps = 36/199 (18%) Query: 159 LVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQ 211 V +SA++L+ C G+ GCNGG+ A+ + KG+ S Y PY Sbjct: 2 SVEVSAEDLLTCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPC 59 Query: 212 KCQYDSKYRAAT-------CSKYTELPY------------------GREDVLKEAVANKG 246 + + T CSK E Y E + + G Sbjct: 60 EHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNG 119 Query: 247 PVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGE 306 PV G + + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ Sbjct: 120 PVE-GAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 178 Query: 307 EGYIRMARNKGNHCGIASF 325 G+ ++ R + +HCGI S Sbjct: 179 NGFFKILRGQ-DHCGIESE 196 >4CI7-A nrPDB Length = 470 Score = 150 bits (379), Expect = 7e-37, Method: Composition-based stats. Identities = 62/239 (25%), Positives = 95/239 (39%), Gaps = 35/239 (14%) Query: 95 LRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154 +PS ++ ++ Y NP + G T K QGS W+FS + LEA LKL Sbjct: 57 SSLPSAYKSSVAY--NPMDL----------GLTTPAKNQGSLNTAWSFSGMSTLEAYLKL 104 Query: 155 KTGKLVSLSAQNLVDCSTE---KYGNKGCNGGFMTTAFQYIIDNKG--IDSDASYPYKAM 209 K LS ++L +T + +G TA Y+ G ++ D Y K+ Sbjct: 105 KGYGTYDLSEEHLRWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSE 164 Query: 210 DQKCQYDSKYRAA----TCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSG 265 Q S A + L +E V K A+ G V+ G A + ++F Sbjct: 165 AQGATKPSNMDTAPTQFNVTDVVRLNKDKETV-KNAIMQYGSVTSGY-AHYSTYFNKDET 222 Query: 266 VYYEPSCTQNVNHGVLVVGYGDLNGKE------------YWLVKNSWGHNFGEEGYIRM 312 Y + +NH V +VG+ D K+ WLVK+SWG +G+ + Sbjct: 223 AYNCTNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 281 >3CH2-X nrPDB Length = 265 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 55/233 (23%), Positives = 100/233 (42%), Gaps = 36/233 (15%) Query: 123 EKGCVT--EVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 180 E C++ +V+ QG+C W F++ LE +K + +SA + +C ++ ++ C Sbjct: 15 ENNCISNLQVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDR-C 73 Query: 181 NGGFMTTAFQYIIDNKG-IDSDASYPY-----------------------KAMDQKCQYD 216 + G F II++ G + ++++YPY K + K + + Sbjct: 74 DEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 133 Query: 217 S----KYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC 272 S Y A ++ + ++K V NKG V + A + + + Sbjct: 134 SLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKVQNLCG 193 Query: 273 TQNVNHGVLVVGYGDL-----NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHC 320 +H V +VGYG+ K YW+V+NSWG +G+EGY ++ HC Sbjct: 194 DDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >4D59-A nrPDB Length = 406 Score = 147 bits (371), Expect = 7e-36, Method: Composition-based stats. Identities = 57/209 (27%), Positives = 84/209 (40%), Gaps = 23/209 (11%) Query: 125 GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTE---KYGNKGCN 181 G T K QGS W+FS + LEA LKLK LS ++L +T + + Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 182 GGFMTTAFQYIIDNKG--IDSDASYPYKAMDQKCQYDSKYRAA----TCSKYTELPYGRE 235 G TA Y+ G ++ D Y K+ Q S A + L +E Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKE 130 Query: 236 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKE--- 292 V K A+ G V+ G A + ++F Y + +NH V +VG+ D K+ Sbjct: 131 TV-KNAIMQYGSVTSGY-AHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKDNFA 188 Query: 293 ---------YWLVKNSWGHNFGEEGYIRM 312 WLVK+SWG +G+ + Sbjct: 189 SDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >5I4H-B nrPDB Length = 112 Score = 147 bits (371), Expect = 7e-36, Method: Composition-based stats. Identities = 54/111 (48%), Positives = 79/111 (71%), Gaps = 6/111 (5%) Query: 226 KYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVG 284 + ++P +E L +AVA GP+SV +DA H SF Y+ G+Y+EP C+ ++++HGVLVVG Sbjct: 3 GFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG 61 Query: 285 YG----DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 YG + + +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 62 YGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >1SP4-B nrPDB Length = 205 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 36/198 (18%) Query: 160 VSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQK 212 V +SA++++ C + G+ NGGF + A+ + KG+ S Y PY + Sbjct: 4 VEVSAEDMLTCCGGECGDGC-NGGFPSGAWNFWTK-KGLVSGGLYNSHVGCRPYSIPPCE 61 Query: 213 CQYDSKYRAAT-------CSKYTELPY------------------GREDVLKEAVANKGP 247 + T C+K E Y E + + GP Sbjct: 62 HHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGP 121 Query: 248 VSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEE 307 V G + + F LY+SGVY S H + ++G+G NG YWLV NSW ++G+ Sbjct: 122 VE-GAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDN 180 Query: 308 GYIRMARNKGNHCGIASF 325 G+ ++ R + +HCGI S Sbjct: 181 GFFKILRGQ-DHCGIESE 197 >2L95-A nrPDB Length = 80 Score = 85.8 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 24 LDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDM 83 D W +K + K Y E E+ +RR I+ ++ + HN + G ++ +G+NHL D+ Sbjct: 6 SDEEWVEYKSKFDKNY-EAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADL 64 Query: 84 TSEEVMSLMSSLRVP 98 T EE + S +VP Sbjct: 65 TPEEF-AQRSGKKVP 78 >4OEM-B nrPDB Length = 70 Score = 81.6 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 3/55 (5%) Query: 274 QNVNHGVLVVGYGD--LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFP 326 + NH VL+VGYG +G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 7 ELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESIA 60 >3OIS-A nrPDB Length = 291 Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 53/256 (20%), Positives = 87/256 (33%), Gaps = 61/256 (23%) Query: 95 LRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTE---VKYQGSCGACWAFSAVGALEAQ 151 + + T + + LP VD +T V QG G+C A + A++ Sbjct: 37 PDIADIRDFSYTPEKSVIAALPPKVD------LTPPFQVYDQGRIGSCTANALAAAIQ-F 89 Query: 152 LKLKTGKLVSLSAQNLVDCSTEKYGNKGCNG------GFMTTAFQYIIDNKGIDSDASYP 205 ++ + L Y + G G M ++ G+ + +P Sbjct: 90 ERIHDKQSPEFIPSRL----FIYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEWP 145 Query: 206 Y-------------------KAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKG 246 Y K +C D++ ++Y+ + D LK +A Sbjct: 146 YGDTPADPRTEEFPPGAPASKKPSDQCYKDAQN--YKITEYSRVAQ-DIDHLKACLAVGS 202 Query: 247 PVSVGVDARHPSFFLYRSGVYYEP----------SCTQNVNHGVLVVGYGDLNGKEYWLV 296 P G F +Y S V + T H VL VGY D ++ + Sbjct: 203 PFVFG-------FSVYNSWVGNNSLPVRIPLPTKNDTLEGGHAVLCVGYDDE--IRHFRI 253 Query: 297 KNSWGHNFGEEGYIRM 312 +NSWG+N GE+GY M Sbjct: 254 RNSWGNNVGEDGYFWM 269 >4K7C-A nrPDB Length = 446 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 272 CTQNVNHGVLVVGYGDLNGKEY-WLVKNSWGHNFGEEGYI 310 + H +++ G ++GK W V+NSWG GE+GY Sbjct: 358 GESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 16/30 (53%), Gaps = 4/30 (13%) Query: 130 VKYQGSCGACWAFSAVGAL----EAQLKLK 155 V Q G CW F+A+ + +AQ K+K Sbjct: 61 VSNQKQSGRCWMFAALNTMRHGIQAQFKIK 90 >5WDK-A nrPDB Length = 401 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 47/131 (35%), Gaps = 21/131 (16%) Query: 123 EKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSA--------QNLVDCSTEK 174 ++ +T VK Q G CW +S+ LE++L LS + D + Sbjct: 36 KENPITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTVYNTYLDRADAAVRT 95 Query: 175 YGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYG 233 +G+ GG A Y ++ G+ + A T S +TEL Sbjct: 96 HGDVSFSQGGSFYDAL-YGMETFGLVPEEE----------MRPGMMYADTLSNHTELSAL 144 Query: 234 REDVLKEAVAN 244 D + A+A Sbjct: 145 T-DAMVAAIAK 154 Score = 36.9 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 270 PSCTQNVNHGVLVVGYG-DLNGKEYWLVKNSWGHNFGEEGYIRMAR 314 + +HG+ + G D G EY++VKNSWG N G ++ Sbjct: 328 DNYETTDDHGMQIYGIAKDQEGNEYYMVKNSWGTNSKYNGIWYASK 373 >2CB5-A nrPDB Length = 453 Score = 35.4 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%), Gaps = 4/45 (8%) Query: 272 CTQNVNHGVLVVGYGDLNGKE----YWLVKNSWGHNFGEEGYIRM 312 + H + + + ++ W V+NSWG + G +GY+ M Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >2QGM-A nrPDB Length = 445 Score = 35.0 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 37/213 (17%), Positives = 65/213 (30%), Gaps = 45/213 (21%) Query: 18 LHKDPTLDHHWHLWKKTYGKQYKEKNE--------EAVRRLIWEKNLKFVMLHN------ 63 L+ + W K Y K + +A+ + + K + +V LH Sbjct: 139 LYPTDEIIAMIE-WMKDYNADPSNKKKIQFIGLDLKALDQGSFNKVIDYVRLHRPDLLAE 197 Query: 64 -LEHSMGMHSYDLGMNHLGDMTSE-EVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDW 121 E+ + S+ + +T + + ++ RV + + I+P Sbjct: 198 VEENYKELSSFTGSIQEYMKLTPKLKEKFKANAERVARLLKDE--NEQANTEIIPSEY-- 253 Query: 122 REKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGK----LVSLSAQNLVDCSTEKYGN 177 WA + A+E + ++ L Q L D + Sbjct: 254 -----------------IWAKATASAIEKFTTMLLPNDYPSIIKLHEQYLADHAMWAQET 296 Query: 178 KGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMD 210 G G M A I KGI + YPY A Sbjct: 297 FG--GKTMVWAHN-IHIAKGIIDEKLYPYVAGQ 326 >4YE5-A nrPDB Length = 566 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 50 LIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGD-MTSEEVMSLMSSLRVPSQWQRNITYK 108 ++ + H + S ++GM GD MT+E+ + +S + N+ + Sbjct: 320 QTYKDAVDHGNEHWTLAGILEQSSNVGMVIAGDKMTNEQRYNFISKFGIGQATGLNLPGE 379 Query: 109 SNPNRILPDSVDWREKGCV 127 S DS D R + V Sbjct: 380 SEGVLHPSDSWDRRTRNTV 398 >3RXZ-A nrPDB Length = 300 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 36/112 (32%), Gaps = 16/112 (14%) Query: 41 EKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQ 100 +E+ R+ I + ++ + H +G + MN E L S + S Sbjct: 116 GADEDTERK-ILTRGIEALEEVAGVHPVGYRAPMWEMNWHTPKLLAEFGFLYDSTLMDSD 174 Query: 101 WQRNITYKSNPNRILPDSV---DWREKGCVTEVKYQGSCGACWAFSAVGALE 149 + LP S DW++ V + FS G +E Sbjct: 175 HPYELAVGDGSLVELPVSWALDDWQQYCFVPD------------FSGTGLIE 214 >4W8N-A nrPDB Length = 330 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 5/58 (8%) Query: 153 KLKTGKLVSLS---AQNLVDCSTEKY--GNKGCNGGFMTTAFQYIIDNKGIDSDASYP 205 K GKL LS L DCS + GN C+ + YI++ + + YP Sbjct: 40 KTHNGKLCRLSGIPPLELGDCSIAGWLLGNPECDRLLSVPEWSYIVEKENPVNGLCYP 97 >2WR0-A nrPDB Length = 509 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 5/58 (8%) Query: 153 KLKTGKLVSLS---AQNLVDCSTEKY--GNKGCNGGFMTTAFQYIIDNKGIDSDASYP 205 K GKL LS L DCS + GN C+ + YI++ + + YP Sbjct: 50 KTHNGKLCRLSGIPPLELGDCSIAGWLLGNPECDRLLSVPEWSYIVEKENPVNGLCYP 107 >2XGT-A nrPDB Length = 435 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 44 EEAVRRLIWEKNLKFVMLHNLEHSMGMH-SYDLGMNHLGD--MTSEEVMSLMSSLRVPSQ 100 E R+ ++ +K++ HN+E+ G +Y + + MT ++ + R PS+ Sbjct: 272 ERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGEDIAEAAERFMTDTINKPILLN-RFPSE 330 Query: 101 WQRNITYKSNPNRILPDSVD 120 + + + L +SVD Sbjct: 331 IKAFYMQRDAQDNTLTESVD 350 >1A6R-A nrPDB Length = 471 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 30/88 (34%), Gaps = 14/88 (15%) Query: 85 SEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCV-----TEVKYQGSCGAC 139 ++E S ++ + + + N+ D R V T V Q S G Sbjct: 31 NKEFQSDLTHQLATTVLKNYNADDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRA 90 Query: 140 WAFSAVGALEAQLKLKTGKLVSLSAQNL 167 W F+A L +L LS NL Sbjct: 91 WLFAATNQL---------RLNVLSELNL 109 >4KPS-A nrPDB Length = 324 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 5/56 (8%) Query: 155 KTGKLVSL---SAQNLVDCSTEKY--GNKGCNGGFMTTAFQYIIDNKGIDSDASYP 205 TG SL S +L DCS E + GN C F + Y+I++ YP Sbjct: 39 HTGTYCSLNGVSPVHLGDCSFEGWIVGNPACTSNFGIREWSYLIEDPAAPHGLCYP 94 >2UXY-A nrPDB Length = 341 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 4/67 (5%) Query: 198 IDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAV--ANKGPVSVGVDAR 255 I D +YP D C C Y ++ ++ +A+ AN V+V A Sbjct: 165 ICDDGNYPEIWRD--CAMKGAELIVRCQGYMYPAKDQQVMMAKAMAWANNCYVAVANAAG 222 Query: 256 HPSFFLY 262 + Y Sbjct: 223 FDGVYSY 229 >1L9N-A nrPDB Length = 692 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 18/45 (40%), Gaps = 13/45 (28%) Query: 109 SNPNRILPDSVD--------WREKGCVTEVKYQGSCGACWAFSAV 145 + P S D W++ G ++ V+Y G CW F+ Sbjct: 239 TYTGGRDPRSWDGSVEILKNWKKSG-LSPVRY----GQCWVFAGT 278 >2Z51-A nrPDB Length = 154 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 9/15 (60%), Positives = 11/15 (73%) Query: 125 GCVTEVKYQGSCGAC 139 G V VK QG+CG+C Sbjct: 34 GNVVRVKLQGACGSC 48 >1G0D-A nrPDB Length = 695 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 16/36 (44%), Gaps = 5/36 (13%) Query: 111 PNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVG 146 +P W + G V VKY G CW F+AV Sbjct: 249 WTGSVPILQQWSKAG-VRPVKY----GQCWVFAAVA 279 >3UKH-A nrPDB Length = 519 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 81 GDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135 D+T E + + + S ++ + + LP DW ++ V+ QG Sbjct: 48 TDVTPEGFLYDVGGHVIFSHYK---YFDDCLDEALPKEDDWYTHQRISYVRCQGQ 99 >5AJK-A nrPDB Length = 168 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 23/50 (46%), Gaps = 1/50 (2%) Query: 44 EEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMS 93 ++ R+L K ++ + N+ + Y+ MN + DM S E ++ Sbjct: 58 DDLYRQLP-TKTRSYIDIINMYCDKVNNDYNRDMNIMYDMASTESFTVYD 106 >3PZL-A nrPDB Length = 313 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 12/76 (15%) Query: 57 KFVMLHNLEHSMGMHSYDLGMNHLGDMTSEE------------VMSLMSSLRVPSQWQRN 104 +V L + E+S G+ GM LGDM E V ++MS ++P Sbjct: 64 AYVNLESYEYSYGIDLLASGMADLGDMEESEDVEYVIDTVESVVSAVMSDGKIPIMLGGE 123 Query: 105 ITYKSNPNRILPDSVD 120 + R LP VD Sbjct: 124 HSITVGAVRALPKDVD 139 >5ZRD-A nrPDB Length = 549 Score = 28.4 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 21/61 (34%), Gaps = 5/61 (8%) Query: 182 GGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEA 241 GG+ FQY + D YPY C + + Y Y E+ L+ Sbjct: 54 GGYHGEPFQYRKPVDALPQDDIYPYWG--GYCNHGNVLFPTWHRMYV---YKLEEALQSI 108 Query: 242 V 242 V Sbjct: 109 V 109 >5DMY-A nrPDB Length = 904 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 45/141 (31%), Gaps = 20/141 (14%) Query: 177 NKGCNGGFMTTAFQY--IIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 234 G G + + Y I+D G D Y Y++ ++ LP Sbjct: 613 GSGAVGSWPSPKNSYFGIVDTAGFPKDTYYFYQSQ-----WNDDVHTLHI-----LPAWN 662 Query: 235 EDVLKEAVANKGPVSVGVDARHPSFFLY-RSGVYYEPSCTQNVNHGVLVVGYG----DLN 289 E+V+ + NK PV V DA + + ++ GY + Sbjct: 663 ENVVAKGSGNKVPVVVYTDAAKVKLYFTPKGSTEKRLIGEKSFTKKTTAAGYTYQVYEGT 722 Query: 290 GKEYWLVKN---SWGHNFGEE 307 K+ KN +W + E Sbjct: 723 DKDSTAHKNMYLTWNVPWAEG 743 >1UUQ-A nrPDB Length = 440 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 19/50 (38%) Query: 16 AQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLE 65 + +DP + + W + Y+ + + R EK + V N + Sbjct: 150 GEPVQDPNVTNEWEAFMAKSASFYRSEKAQQEYRKTLEKIITRVNSINGK 199 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.140 0.454 Lambda K H 0.267 0.0432 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,714,613 Number of Sequences: 36641 Number of extensions: 627379 Number of successful extensions: 2302 Number of sequences better than 10.0: 101 Number of HSP's better than 10.0 without gapping: 169 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1525 Number of HSP's gapped (non-prelim): 213 length of query: 331 length of database: 10,336,785 effective HSP length: 97 effective length of query: 234 effective length of database: 6,782,608 effective search space: 1587130272 effective search space used: 1587130272 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)