BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P25454 (400 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3LDA-A nrPDB 820 0.0 1SZP-A nrPDB 661 0.0 5H1C-A nrPDB 480 e-136 1N0W-A nrPDB 375 e-104 1V5W-A nrPDB 327 4e-90 6R3P-A nrPDB 282 2e-76 1PZN-A nrPDB 279 1e-75 2ZUB-A nrPDB 255 3e-68 5KDD-A nrPDB 253 8e-68 5LB2-A nrPDB 234 6e-62 2B21-A nrPDB 216 1e-56 3EWA-A nrPDB 198 3e-51 4DC9-A nrPDB 197 6e-51 2CVH-A nrPDB 93 2e-19 1XMS-A nrPDB 64 8e-11 5JRJ-A nrPDB 60 2e-09 3HR8-A nrPDB 54 1e-07 1MO5-A nrPDB 52 7e-07 1UBG-A nrPDB 51 1e-06 1XP8-A nrPDB 48 9e-06 5LM9-A nrPDB 34 0.094 5LM7-A nrPDB 34 0.10 4WIA-A nrPDB 34 0.10 5MS0-M nrPDB 34 0.12 4O0M-A nrPDB 33 0.23 4YHC-A nrPDB 31 1.2 5GRS-A nrPDB 30 1.3 5LKM-A nrPDB 30 1.7 5C5C-A nrPDB 30 2.4 5B47-B nrPDB 29 2.9 2W0M-A nrPDB 28 5.5 >3LDA-A nrPDB Length = 400 Score = 820 bits (2117), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/400 (99%), Positives = 400/400 (100%) Query: 1 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ 60 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ Sbjct: 1 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ 60 Query: 61 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE 120 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE Sbjct: 61 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE 120 Query: 121 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI 180 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI Sbjct: 121 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI 180 Query: 181 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP 240 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP Sbjct: 181 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP 240 Query: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ 300 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ Sbjct: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ 300 Query: 301 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGF 360 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMA+SSTTRLGF Sbjct: 301 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAYSSTTRLGF 360 Query: 361 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE 400 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE Sbjct: 361 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE 400 >1SZP-A nrPDB Length = 321 Score = 661 bits (1705), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/321 (99%), Positives = 319/321 (99%) Query: 80 FVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 139 VPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL Sbjct: 1 MVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 60 Query: 140 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA Sbjct: 61 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 120 Query: 200 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 259 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL Sbjct: 121 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 180 Query: 260 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV 319 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV Sbjct: 181 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV 240 Query: 320 AVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP 379 AVVVTNQVVAQVDGGMAFNPDPKKP GGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP Sbjct: 241 AVVVTNQVVAQVDGGMAFNPDPKKPTGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP 300 Query: 380 EAECVFAIYEDGVGDPREEDE 400 EAECVFAIYEDGVGDPREEDE Sbjct: 301 EAECVFAIYEDGVGDPREEDE 321 >5H1C-A nrPDB Length = 339 Score = 480 bits (1235), Expect = e-136, Method: Compositional matrix adjust. Identities = 226/341 (66%), Positives = 278/341 (81%), Gaps = 6/341 (1%) Query: 57 LQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRK 116 +Q +A A +E+E++ PI +L+ GI DVKKL E+G HT EAVAYAP+K Sbjct: 5 MQLEANADTSVEEESFGPQ------PISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKK 58 Query: 117 DLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVE 176 +L+ IKGISEAKADK+L EAA+LVPMGF TA +FH RRSE+I +TTGSK LD LL GG+E Sbjct: 59 ELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIE 118 Query: 177 TGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRF 236 TGSITE+FGEFRTGK+Q+CHTLAVTCQ+P+D GGGEGK +YIDTEGTFRP RL+++A+R+ Sbjct: 119 TGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERY 178 Query: 237 GLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGEL 296 GL D L+NVAYARA+N DHQ +LL A+ MM ESR++L++VDS ALYRTD+SGRGEL Sbjct: 179 GLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGEL 238 Query: 297 SARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTT 356 SARQMHLA+F+R L RLAD+FGVAVV+TNQVVAQVDG F DPKKPIGGNI+AH+STT Sbjct: 239 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTT 298 Query: 357 RLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPRE 397 RL +KG+G R+C++ DSPCLPEAE +FAI DGVGD ++ Sbjct: 299 RLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGDAKD 339 >1N0W-A nrPDB Length = 243 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 172/243 (70%), Positives = 208/243 (85%) Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 SE+I +TTGSK LD LL GG+ETGSITE+FGEFRTGK+Q+CHTLAVTCQ+P+D GGGEGK Sbjct: 1 SEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGK 60 Query: 215 CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRF 274 +YIDTEGTFRP RL+++A+R+GL D L+NVAYARA+N DHQ +LL A+ MM ESR+ Sbjct: 61 AMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRY 120 Query: 275 SLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGG 334 +L++VDS ALYRTD+SGRGELSARQMHLA+F+R L RLAD+FGVAVV+TNQVVAQVDG Sbjct: 121 ALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGA 180 Query: 335 MAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGD 394 F DPKKPIGGNI+AH+STTRL +KG+G R+CK+ DSPCLPEAE +FAI DGVGD Sbjct: 181 AMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 240 Query: 395 PRE 397 ++ Sbjct: 241 AKD 243 >1V5W-A nrPDB Length = 343 Score = 327 bits (839), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 160/320 (50%), Positives = 219/320 (68%), Gaps = 2/320 (0%) Query: 80 FVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 139 F I+ LQ +GI +AD+KKL+ G+ T + + R+ L +KG+SEAK DK+ A +L Sbjct: 24 FQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKL 83 Query: 140 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 + GF+TA ++ +R + +TTGS+ D LLGGG+E+ +ITE FGEFRTGK+QL HTL Sbjct: 84 IEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLC 143 Query: 200 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 259 VT Q+P G GK ++IDTE TFRP RL IA RF +D D L+NV YARAY ++HQ+ Sbjct: 144 VTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQM 203 Query: 260 RLLDAAAQMMSESR--FSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQF 317 LLD A E F L+++DS+MAL+R DFSGRGEL+ RQ LA+ + LQ++++++ Sbjct: 204 ELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 263 Query: 318 GVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPC 377 VAV VTNQ+ A M F DPKKPIGG+I+AH+STTR+ +KG+G R+ K+ DSP Sbjct: 264 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPE 323 Query: 378 LPEAECVFAIYEDGVGDPRE 397 +PE E FAI G+GD +E Sbjct: 324 MPENEATFAITAGGIGDAKE 343 >6R3P-A nrPDB Length = 261 Score = 282 bits (721), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 135/257 (52%), Positives = 180/257 (70%), Gaps = 2/257 (0%) Query: 143 GFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTC 202 GF+TA ++ +R + +TTGS+ D LLGGG+E+ +ITE FGEFRTGK+QL HTL VT Sbjct: 5 GFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTA 64 Query: 203 QIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLL 262 Q+P G GK ++IDTE TFRP RL IA RF +D D L+NV YARAY ++HQ+ LL Sbjct: 65 QLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELL 124 Query: 263 DAAAQMMSESR--FSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVA 320 D A E F L+++DS+MAL+R DFSGRGEL+ RQ LA+ + LQ++++++ VA Sbjct: 125 DYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVA 184 Query: 321 VVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPE 380 V VTNQ+ A M F DPKKPIGG+I+AH+STTR+ +KG+G R+ K+ DSP +PE Sbjct: 185 VFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPE 244 Query: 381 AECVFAIYEDGVGDPRE 397 E FAI G+GD +E Sbjct: 245 NEATFAITAGGIGDAKE 261 >1PZN-A nrPDB Length = 349 Score = 279 bits (714), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 144/311 (46%), Positives = 213/311 (68%), Gaps = 9/311 (2%) Query: 90 GITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMG-FVTAA 148 G+ A +KLRE+G T EA+A A +L E+ GISE A K++ A + +G F+ A Sbjct: 42 GVGPATAEKLREAGYDTLEAIAVASPIELKEVAGISEGTALKIIQAARKAANLGTFMRAD 101 Query: 149 DFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDI 208 ++ +R+ + ++TGSK+LD LLGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + Sbjct: 102 EYLKKRATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEE 161 Query: 209 GGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLL----DA 264 GG G ++IDTE TFRP R+ IAQ GLDPD+ L ++ ARA+N++HQ+ L+ D Sbjct: 162 GGLNGSVIWIDTENTFRPERIREIAQNRGLDPDEVLKHIYVARAFNSNHQMLLVQQAEDK 221 Query: 265 AAQMMSESR-FSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVV 323 ++++ R L++VDS+ + +R+++ GRG L+ RQ LAK + L RLA+ + +AV V Sbjct: 222 IKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFV 281 Query: 324 TNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAEC 383 TNQV A+ D AF DP +PIGG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E Sbjct: 282 TNQVQARPD---AFFGDPTRPIGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEA 338 Query: 384 VFAIYEDGVGD 394 VF+I E G+ D Sbjct: 339 VFSITEKGIED 349 >2ZUB-A nrPDB Length = 324 Score = 255 bits (651), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 131/309 (42%), Positives = 195/309 (63%), Gaps = 4/309 (1%) Query: 90 GITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAAD 149 GI+ + KL E+G + E +A A +DL GI + A K++ EA + + F TA + Sbjct: 19 GISQTVINKLIEAGYSSLETLAVASPQDLSVAAGIPLSTAQKIIKEARDALDIRFKTALE 78 Query: 150 FHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIG 209 R + ++TGS+ LD LL GG+ET ++TE FGEF +GK+QLCH L+V Q+P + G Sbjct: 79 VKKERMNVKKISTGSQALDGLLAGGIETRTMTEFFGEFGSGKTQLCHQLSVNVQLPPEKG 138 Query: 210 GGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMM 269 G GK +YIDTEGTFR R+ ++A+ GLD D+ +NN+ Y RA N DHQ+ ++D +++ Sbjct: 139 GLSGKAVYIDTEGTFRWERIENMAKALGLDIDNVMNNIYYIRAINTDHQIAIVDDLQELV 198 Query: 270 S-ESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVV 328 S + LIVVDSV + +R ++ GR L+ RQ L K + L RLA+ + +AV++TNQV+ Sbjct: 199 SKDPSIKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLTRLAEVYDIAVIITNQVM 258 Query: 329 AQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIY 388 A+ D F DP +GG+ + H R+ KK +G +R+ +VVD+P LPE E VFA+ Sbjct: 259 ARPD---MFYGDPTVAVGGHTLYHVPGIRIQLKKSRGNRRIARVVDAPHLPEGEVVFALT 315 Query: 389 EDGVGDPRE 397 E+G+ D E Sbjct: 316 EEGIRDAEE 324 >5KDD-A nrPDB Length = 231 Score = 253 bits (647), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 124/240 (51%), Positives = 171/240 (71%), Gaps = 20/240 (8%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYID 219 ++TGSK+LD LLGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + GG G +YID Sbjct: 7 ISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSAMYID 66 Query: 220 TEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESR-----F 274 TE TFRP RL IAQ GLDPD+ L+NVAYARA+N++HQ++LL A+ MM ES + Sbjct: 67 TENTFRPERLREIAQNRGLDPDEVLDNVAYARAFNSNHQMQLLYQASAMMVESLNTDRPY 126 Query: 275 SLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGG 334 L++VDS+ + +R+++ GRG L+ RQ LA+F+R L RLA++F +AV VTNQV A Sbjct: 127 KLLIVDSLTSHFRSEYIGRGALAERQQKLARFLRMLHRLANEFDIAVFVTNQVQAN---- 182 Query: 335 MAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGD 394 GG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E VF+I E G+ D Sbjct: 183 -----------GGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 231 >5LB2-A nrPDB Length = 230 Score = 234 bits (596), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 115/240 (47%), Positives = 164/240 (68%), Gaps = 21/240 (8%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYID 219 ++TGSK+LD LLGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + GG G ++ID Sbjct: 7 ISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVMWID 66 Query: 220 TEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSE-----SRF 274 TE TFRP R+ IAQ GLDPD+ L ++AYARA+N++HQ+ L+ A+ M+ E Sbjct: 67 TENTFRPERIREIAQNRGLDPDEVLKHIAYARAFNSNHQMLLVQQASAMIKELLNTDRPV 126 Query: 275 SLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGG 334 L++VDS+ + +R+++ GRG L+ RQ LAK + L RLA+ + +AV VTNQV A Sbjct: 127 KLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVQA----- 181 Query: 335 MAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGD 394 GG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E VF+I E G+ D Sbjct: 182 -----------GGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 230 >2B21-A nrPDB Length = 322 Score = 216 bits (551), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 124/316 (39%), Positives = 188/316 (59%), Gaps = 14/316 (4%) Query: 90 GITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAAD 149 G+ + +KL E+G +A A +L +I+GISE A K++ A L +GF + D Sbjct: 10 GVGPSTAEKLVEAGYIDFMKIATATVGELTDIEGISEKAAAKMIMGARDLCDLGFKSGID 69 Query: 150 FHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIP---- 205 +RS + L+T S LD++LGGG+E+ S+TE G F +GK+Q+ H V Q P Sbjct: 70 LLKQRSTVWKLSTSSSELDSVLGGGLESQSVTEFAGVFGSGKTQIMHQSCVNLQNPEFLF 129 Query: 206 ---LDIGGGE---GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 259 + GE K +YIDTEGTFRP R++ +A+ G+D L+N ARAYN+D Q+ Sbjct: 130 YDEEAVSKGEVAQPKAVYIDTEGTFRPERIMQMAEHAGIDGQTVLDNTFVARAYNSDMQM 189 Query: 260 RLLDAAAQMMSE-SRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFG 318 + ++ E + L+V+DS+ + +R +++GRG+L+ RQ L + M L +LAD F Sbjct: 190 LFAEKIEDLIQEGNNIKLVVIDSLTSTFRNEYTGRGKLAERQQKLGRHMATLNKLADLFN 249 Query: 319 VAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCL 378 V+VTNQV A+ D AF ++ IGG+I+ H++T R +KGKG +R+ K+ DSP L Sbjct: 250 CVVLVTNQVSAKPD---AFFGMAEQAIGGHIVGHAATFRFFVRKGKGDKRVAKLYDSPHL 306 Query: 379 PEAECVFAIYEDGVGD 394 P+AE +F I E G+ D Sbjct: 307 PDAEAIFRITEKGIQD 322 >3EWA-A nrPDB Length = 322 Score = 198 bits (504), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 117/319 (36%), Positives = 183/319 (57%), Gaps = 14/319 (4%) Query: 87 QVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVT 146 ++ G+ + KL E G +A A +L +I+GISE A K++ A L +GF + Sbjct: 7 ELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKS 66 Query: 147 AADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPL 206 + +R + L+TGS LDT+L GG+E+ S+TE G F +GK+Q+ H V Q+ Sbjct: 67 GVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQMRE 126 Query: 207 DIGGGEG----------KCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNAD 256 I K +YIDTEGTFRP R+V +A+ G+D L+N ARAYN+D Sbjct: 127 KIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQMAEGAGIDGQTVLDNTFVARAYNSD 186 Query: 257 HQLRLLDAAAQMMS-ESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLAD 315 Q+ + ++ + L+++DS+ + +R +F+GRG+L+ RQ L + M L +LAD Sbjct: 187 MQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLAD 246 Query: 316 QFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDS 375 + V+VTNQV A+ D A+ ++ IGG+++ H++T R +K KG +R+ K+ DS Sbjct: 247 LYNCIVLVTNQVAAKPD---AYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDS 303 Query: 376 PCLPEAECVFAIYEDGVGD 394 P LP++E VF I E G+ D Sbjct: 304 PHLPDSEAVFRITEKGIQD 322 >4DC9-A nrPDB Length = 266 Score = 197 bits (502), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 108/264 (40%), Positives = 162/264 (61%), Gaps = 14/264 (5%) Query: 142 MGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVT 201 +GF + D +RS + L+T S LD++LGGG+E+ S+TE G F +GK+Q+ H V Sbjct: 6 LGFKSGIDLLKQRSTVWKLSTSSSELDSVLGGGLESQSVTEFAGVFGSGKTQIMHQSCVN 65 Query: 202 CQIP----LD---IGGGE---GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYAR 251 Q P D + GE K +YIDTEGTFRP R++ +A+ G+D L+N AR Sbjct: 66 LQNPEFLFYDEEAVSKGEVAQPKAVYIDTEGTFRPERIMQMAEHAGIDGQTVLDNTFVAR 125 Query: 252 AYNADHQLRLLDAAAQMMSE-SRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRAL 310 AYN+D Q+ + ++ E + L+V+DS+ + +R +++GRG+L+ RQ L + M L Sbjct: 126 AYNSDMQMLFAEKIEDLIQEGNNIKLVVIDSLTSTFRNEYTGRGKLAERQQKLGRHMATL 185 Query: 311 QRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLC 370 +LAD F V+VTNQV A+ D AF ++ IGG+I+ H++T R +KGKG +R+ Sbjct: 186 NKLADLFNCVVLVTNQVSAKPD---AFFGMAEQAIGGHIVGHAATFRFFVRKGKGDKRVA 242 Query: 371 KVVDSPCLPEAECVFAIYEDGVGD 394 K+ DSP LP+AE +F I E G+ D Sbjct: 243 KLYDSPHLPDAEAIFRITEKGIQD 266 >2CVH-A nrPDB Length = 220 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 58/169 (34%), Positives = 99/169 (58%), Gaps = 16/169 (9%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCL-YI 218 L+TG+K+LD+LLGGG G +T+++G + +GK+ L L G GK + Y+ Sbjct: 2 LSTGTKSLDSLLGGGFAPGVLTQVYGPYASGKTTLA----------LQTGLLSGKKVAYV 51 Query: 219 DTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIV 278 DTEG F P RLV +A+ GL+P++AL+ + Q R++ + + + +S F+L+V Sbjct: 52 DTEGGFSPERLVQMAETRGLNPEEALSRFILFTPSDFKEQRRVIGSLKKTV-DSNFALVV 110 Query: 279 VDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQV 327 VDS+ A YR + + G ++ L++ ++ L +A + + V+V NQV Sbjct: 111 VDSITAHYRAEENRSGLIA----ELSRQLQVLLWIARKHNIPVIVINQV 155 >1XMS-A nrPDB Length = 356 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 29/217 (13%) Query: 153 RRSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGG 211 R ++ ++TGS +LD LG GG+ G I E++G +GK+ L + Q Sbjct: 37 RSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQ-------R 89 Query: 212 EGK-CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMS 270 EGK C +ID E P+ A++ G+D D N+ ++ + L + DA A+ Sbjct: 90 EGKTCAFIDAEHALDPI----YARKLGVDID----NLLCSQPDTGEQALEICDALAR--- 138 Query: 271 ESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFM--RALQRLA---DQFGVAVVVTN 325 +IVVDSV AL GE+ M LA M +A+++LA Q ++ N Sbjct: 139 SGAVDVIVVDSVAAL-TPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFIN 197 Query: 326 QVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK 362 Q+ ++ G+ F +P+ GGN + ++ RL ++ Sbjct: 198 QIRMKI--GVMFG-NPETTTGGNALKFYASVRLDIRR 231 >5JRJ-A nrPDB Length = 351 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 61/214 (28%), Positives = 103/214 (48%), Gaps = 29/214 (13%) Query: 156 ELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 E+ ++TGS LD LG GG+ G + E++G +GK+ L T Q ++ G Sbjct: 43 EIQAVSTGSLGLDIALGIGGLPRGRVIEIYGPESSGKTTL------TLQSIAEMQKLGGT 96 Query: 215 CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRF 274 C +ID E V+ AQ+ G++ LN++ ++ + L + DA ++ Sbjct: 97 CAFIDAEHALD----VTYAQKLGVN----LNDLLISQPDTGEQALEICDA---LVRSGAV 145 Query: 275 SLIVVDSVMALY-RTDFSG-RGE----LSARQMHLAKFMRALQRLADQFGVAVVVTNQVV 328 LIVVDSV AL + + G G+ L AR M A +R L ++ V+ NQ+ Sbjct: 146 DLIVVDSVAALTPKAEIEGDMGDSLPGLQARLMSQA--LRKLTGSINRTNTTVIFINQIR 203 Query: 329 AQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK 362 ++ G+ F +P+ GGN + ++ RL ++ Sbjct: 204 MKI--GVMFG-NPETTTGGNALKFYASVRLDIRR 234 >3HR8-A nrPDB Length = 356 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 65/253 (25%), Positives = 107/253 (42%), Gaps = 42/253 (16%) Query: 159 CLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLC-HTLAVTCQIPLDIGGGEGKCL 216 + TGS +D G GG G I E+FG+ +GK+ L H +A ++ G Sbjct: 41 VIPTGSLAIDIATGVGGYPRGRIVEIFGQESSGKTTLALHAIAEAQKMG-------GVAA 93 Query: 217 YIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSL 276 +ID E PV A+ G+D L + DH + L+ +++ L Sbjct: 94 FIDAEHALDPV----YAKNLGVDLKSLLIS-------QPDHGEQALEIVDELVRSGVVDL 142 Query: 277 IVVDSVMALY-RTDFSG-----RGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQ 330 IVVDSV AL R + G + L AR M A +R + ++ V+ TNQ+ + Sbjct: 143 IVVDSVAALVPRAEIEGAMGDMQVGLQARLMSQA--LRKIAGSVNKSKAVVIFTNQIRMK 200 Query: 331 VDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQR---------LCKVVDSPCLPEA 381 + G+ F P+ GG + +T R+ ++G+ + K+V + P Sbjct: 201 I--GVMFG-SPETTTGGLALKFYATMRMEVRRGEPIKEGKDVIGNVISVKIVKNKVAPPF 257 Query: 382 EC--VFAIYEDGV 392 + + IY G+ Sbjct: 258 KTAQTYIIYGKGI 270 >1MO5-A nrPDB Length = 350 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 64/257 (24%), Positives = 105/257 (40%), Gaps = 40/257 (15%) Query: 154 RSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGE 212 R + + TGS LD LG GG+ G + E++G +GK+ + Q Sbjct: 35 RQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ------AAG 88 Query: 213 GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSES 272 G +ID E P A++ G+D D L D + L+ A ++ Sbjct: 89 GVAAFIDAEHALDP----DYAKKLGVDTDSLL-------VSQPDTGEQALEIADMLIRSG 137 Query: 273 RFSLIVVDSVMALY-RTDFSGR-GE----LSARQMHLAKFMRALQRLADQFGVAVVVTNQ 326 ++V+DSV AL R + G G+ L AR M A +R + + G + NQ Sbjct: 138 ALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQA--LRKMTGALNNSGTTAIFINQ 195 Query: 327 VVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK---------GKGCQRLCKVVDSPC 377 + ++ G+ F P+ GG + ++ R+ ++ G + KVV + C Sbjct: 196 LRDKI--GVMFG-SPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKC 252 Query: 378 L-PEAECVFAI-YEDGV 392 L P + F I Y G+ Sbjct: 253 LAPFKQAEFDILYGKGI 269 >1UBG-A nrPDB Length = 349 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/216 (25%), Positives = 91/216 (42%), Gaps = 29/216 (13%) Query: 154 RSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGE 212 R + + TGS +LD LG GG+ G + E++G +GK+ + Q Sbjct: 36 RQPISVIPTGSISLDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ------AAG 89 Query: 213 GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSES 272 G +ID E P A++ G+D D L D + L+ A ++ Sbjct: 90 GIAAFIDAEHALDP----EYAKKLGVDTDSLL-------VSQPDTGEQALEIADMLVRSG 138 Query: 273 RFSLIVVDSVMALY-RTDFSGR-GE----LSARQMHLAKFMRALQRLADQFGVAVVVTNQ 326 +IV+DSV AL R + G G+ L AR M A +R + + G + NQ Sbjct: 139 ALDIIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQA--LRKMTGALNNSGTTAIFINQ 196 Query: 327 VVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK 362 + ++ G+ F P+ GG + ++ RL ++ Sbjct: 197 LREKI--GVMFG-SPETTTGGKALKFYASVRLDVRR 229 >1XP8-A nrPDB Length = 366 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 27/210 (12%) Query: 159 CLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLY 217 ++TGS +LD LG GG+ G ITE++G GK+ L + Q G C + Sbjct: 54 VVSTGSLSLDLALGVGGIPRGRITEIYGPESGGKTTLALAIVAQAQ------KAGGTCAF 107 Query: 218 IDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLI 277 ID E PV A+ G++ D+ L ++ N + L +++ + S + ++ Sbjct: 108 IDAEHALDPV----YARALGVNTDELL----VSQPDNGEQALEIMELLVR--SGAIDVVV 157 Query: 278 VVDSVMALYRTDFSG-RGE----LSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVD 332 V R + G G+ L AR M A +R L + + G A + NQV ++ Sbjct: 158 VDSVAALTPRAEIEGDMGDSLPGLQARLMSQA--LRKLTAILSKTGTAAIFINQVREKI- 214 Query: 333 GGMAFNPDPKKPIGGNIMAHSSTTRLGFKK 362 G M NP+ GG + ++ RL +K Sbjct: 215 GVMYGNPE--TTTGGRALKFYASVRLDVRK 242 >5LM9-A nrPDB Length = 329 Score = 34.3 bits (77), Expect = 0.094, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 22/38 (57%) Query: 99 LRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEA 136 L E G T E +AY P K+LLEI+G+ E + L A Sbjct: 276 LVEEGFSTLEELAYVPMKELLEIEGLDEPTVEALRERA 313 >5LM7-A nrPDB Length = 428 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 22/38 (57%) Query: 99 LRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEA 136 L E G T E +AY P K+LLEI+G+ E + L A Sbjct: 375 LVEEGFSTLEELAYVPMKELLEIEGLDEPTVEALRERA 412 >4WIA-A nrPDB Length = 233 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 22/34 (64%) Query: 166 NLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 +LD +GGG+ GS+ + GE TGKS LC LA Sbjct: 15 DLDKRIGGGIPHGSLIIIEGEESTGKSVLCQRLA 48 >5MS0-M nrPDB Length = 497 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 22/38 (57%) Query: 99 LRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEA 136 L E G T E +AY P K+LLEI+G+ E + L A Sbjct: 375 LVEEGFSTLEELAYVPMKELLEIEGLDEPTVEALRERA 412 >4O0M-A nrPDB Length = 524 Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust. Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 25/180 (13%) Query: 117 DLLEIKGISEAKADK--LLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGG 174 ++L+++G + K + +N + P+G + +RS + +++G K LD + GGG Sbjct: 222 EILKLRGTTHMKGEYPFTINNGINIFPLGAMRLT----QRSSNVRVSSGVKTLDEMCGGG 277 Query: 175 VETGSITELFGEFRTGKSQLCHTLAVT-CQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIA 233 SI G TGK+ L T CQ GE L+ E +L A Sbjct: 278 FFKDSIILATGATGTGKTLLVSKFLETGCQ------QGERALLFAYEESR---AQLSRNA 328 Query: 234 QRFGLDPDDALNN------VAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYR 287 +G+D ++ AY + + L+++ + SR + +DS+ AL R Sbjct: 329 SSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSR---VAIDSLSALAR 385 >4YHC-A nrPDB Length = 468 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 185 GEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDAL 244 G+FR C T AVT ++ G E YI + LV + DPD++L Sbjct: 280 GQFRVSSISFCFTHAVTEKVLYYYYGNESNESYIILNKWDQQPNLVDVH-----DPDNSL 334 Query: 245 NNVAYARAYNADHQLRLLDAAAQMMS 270 ++ + H++ DA+ +MS Sbjct: 335 ASLTFDELQENIHEVE--DASESVMS 358 >5GRS-A nrPDB Length = 396 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 185 GEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDAL 244 G+FR C T AVT ++ G E YI + LV + DPD++L Sbjct: 280 GQFRVSSISFCFTHAVTEKVLYYYYGNESNESYIILNKWDQQPNLVDVH-----DPDNSL 334 Query: 245 NNVAYARAYNADHQLRLLDAAAQMMS 270 ++ + H++ DA+ +MS Sbjct: 335 ASLTFDELQENIHEVE--DASESVMS 358 >5LKM-A nrPDB Length = 452 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 32/172 (18%) Query: 141 PMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAV 200 PM ++ R++ T + + +LGGGV GS+ + G+ GKS L L V Sbjct: 56 PMKLAEVTSINVNRTK-----TEMEEFNRVLGGGVVPGSLVLIGGDPGIGKSTLL--LQV 108 Query: 201 TCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLR 260 + Q+ G LY+ E + + ++L A+R G D D A+ ++ Sbjct: 109 STQL-----SQVGTVLYVSGEESAQQIKLR--AERLG-DIDSEF-------YLYAETNMQ 153 Query: 261 LLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRG-------ELSARQMHLAK 305 + A + + +++DS+ + + SG E++A M LAK Sbjct: 154 SVRAEVERIQP---DFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAK 202 >5C5C-A nrPDB Length = 481 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 74 EAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYA 113 + LG P+ +G+ D+K RE+G+H EA+ YA Sbjct: 16 DVTLGGLFPVHAKGPSGVPCGDIK--RENGIHRLEAMLYA 53 >5B47-B nrPDB Length = 304 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Query: 57 LQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRK 116 ++++ EAQ + E G +PI N + +L + + E Y P K Sbjct: 226 VRKEEEAQKKFEQAIMKSYEWGEKIPIGIFYQNELVPTFEDRLTSNIPNYRE---YYPAK 282 Query: 117 DLLEIKGISEAKADKLLNEAARL 139 +EI GIS K D+L+ +A R+ Sbjct: 283 QQIEINGISTTKIDELI-KAKRI 304 >2W0M-A nrPDB Length = 235 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 12/87 (13%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQL-CHTLAVTCQIPLDIGGGEGK-CLY 217 L+TG + D L+ GG+ G L GE TGK+ H +A G +G C+Y Sbjct: 5 LSTGILDFDKLIQGGIPQGFFIALTGEPGTGKTIFSLHFIAK--------GLRDGDPCIY 56 Query: 218 IDTEGTFRPVRLVSIAQRFGLDPDDAL 244 + TE + + + A++F D ++ + Sbjct: 57 VTTEESRDSI--IRQAKQFNWDFEEYI 81 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3LDA-A nrPDB 620 e-178 1SZP-A nrPDB 487 e-138 5H1C-A nrPDB 465 e-131 1V5W-A nrPDB 422 e-118 1PZN-A nrPDB 403 e-113 2B21-A nrPDB 396 e-111 2ZUB-A nrPDB 392 e-109 3EWA-A nrPDB 377 e-105 1N0W-A nrPDB 347 6e-96 6R3P-A nrPDB 347 7e-96 4DC9-A nrPDB 330 6e-91 5KDD-A nrPDB 313 6e-86 5LB2-A nrPDB 306 9e-84 1MO5-A nrPDB 209 1e-54 1UBG-A nrPDB 205 3e-53 3HR8-A nrPDB 203 1e-52 1XMS-A nrPDB 196 2e-50 2CVH-A nrPDB 187 1e-47 5JRJ-A nrPDB 186 1e-47 1XP8-A nrPDB 169 1e-42 Sequences not found previously or not previously below threshold: 2W0M-A nrPDB 57 2e-08 2Q6T-A nrPDB 55 6e-08 2DR3-A nrPDB 51 1e-06 5JWO-A nrPDB 51 1e-06 5LKM-A nrPDB 49 2e-06 4O0M-A nrPDB 48 7e-06 4YDS-A nrPDB 46 2e-05 3S1A-A nrPDB 46 3e-05 4WIA-A nrPDB 45 4e-05 4TLD-A nrPDB 45 6e-05 5MS0-M nrPDB 42 4e-04 5HM5-A nrPDB 40 0.001 5LM7-A nrPDB 39 0.004 5LM9-A nrPDB 39 0.004 3CCJ-Y nrPDB 38 0.006 2R6A-A nrPDB 38 0.006 5VQ9-D nrPDB 37 0.010 3B0X-A nrPDB 37 0.016 2ZJ8-A nrPDB 37 0.021 2V1U-A nrPDB 34 0.10 1HQM-A nrPDB 34 0.14 2QZ4-A nrPDB 33 0.21 5G4G-A nrPDB 32 0.40 2UVV-A nrPDB 32 0.48 4F4Z-B nrPDB 32 0.53 5M32-h nrPDB 32 0.59 5U1D-A nrPDB 31 0.75 5E7P-A nrPDB 31 0.91 5GJQ-J nrPDB 31 0.92 2QW5-A nrPDB 31 1.0 5VHP-C nrPDB 30 1.8 3JCO-J nrPDB 30 2.0 5BN5-A nrPDB 30 2.1 1WNB-A nrPDB 30 2.6 1JJ7-A nrPDB 29 2.8 5TV4-A nrPDB 29 3.6 4QIW-C nrPDB 29 3.7 4AYX-A nrPDB 29 4.1 6IC4-I nrPDB 29 4.4 1IW7-A nrPDB 29 5.5 >3LDA-A nrPDB Length = 400 Score = 620 bits (1598), Expect = e-178, Method: Composition-based stats. Identities = 399/400 (99%), Positives = 400/400 (100%) Query: 1 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ 60 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ Sbjct: 1 MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQ 60 Query: 61 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE 120 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE Sbjct: 61 AEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE 120 Query: 121 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI 180 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI Sbjct: 121 IKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSI 180 Query: 181 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP 240 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP Sbjct: 181 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP 240 Query: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ 300 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ Sbjct: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQ 300 Query: 301 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGF 360 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMA+SSTTRLGF Sbjct: 301 MHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAYSSTTRLGF 360 Query: 361 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE 400 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE Sbjct: 361 KKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE 400 >1SZP-A nrPDB Length = 321 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 319/321 (99%), Positives = 319/321 (99%) Query: 80 FVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 139 VPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL Sbjct: 1 MVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 60 Query: 140 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA Sbjct: 61 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 120 Query: 200 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 259 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL Sbjct: 121 VTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQL 180 Query: 260 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV 319 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV Sbjct: 181 RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV 240 Query: 320 AVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP 379 AVVVTNQVVAQVDGGMAFNPDPKKP GGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP Sbjct: 241 AVVVTNQVVAQVDGGMAFNPDPKKPTGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP 300 Query: 380 EAECVFAIYEDGVGDPREEDE 400 EAECVFAIYEDGVGDPREEDE Sbjct: 301 EAECVFAIYEDGVGDPREEDE 321 >5H1C-A nrPDB Length = 339 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 226/341 (66%), Positives = 278/341 (81%), Gaps = 6/341 (1%) Query: 57 LQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRK 116 +Q +A A +E+E++ PI +L+ GI DVKKL E+G HT EAVAYAP+K Sbjct: 5 MQLEANADTSVEEESFGPQ------PISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKK 58 Query: 117 DLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVE 176 +L+ IKGISEAKADK+L EAA+LVPMGF TA +FH RRSE+I +TTGSK LD LL GG+E Sbjct: 59 ELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIE 118 Query: 177 TGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRF 236 TGSITE+FGEFRTGK+Q+CHTLAVTCQ+P+D GGGEGK +YIDTEGTFRP RL+++A+R+ Sbjct: 119 TGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERY 178 Query: 237 GLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGEL 296 GL D L+NVAYARA+N DHQ +LL A+ MM ESR++L++VDS ALYRTD+SGRGEL Sbjct: 179 GLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGEL 238 Query: 297 SARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTT 356 SARQMHLA+F+R L RLAD+FGVAVV+TNQVVAQVDG F DPKKPIGGNI+AH+STT Sbjct: 239 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTT 298 Query: 357 RLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPRE 397 RL +KG+G R+C++ DSPCLPEAE +FAI DGVGD ++ Sbjct: 299 RLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGDAKD 339 >1V5W-A nrPDB Length = 343 Score = 422 bits (1086), Expect = e-118, Method: Composition-based stats. Identities = 163/338 (48%), Positives = 225/338 (66%), Gaps = 2/338 (0%) Query: 62 EAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEI 121 E Q E+ + + F I+ LQ +GI +AD+KKL+ G+ T + + R+ L + Sbjct: 6 EDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNV 65 Query: 122 KGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSIT 181 KG+SEAK DK+ A +L+ GF+TA ++ +R + +TTGS+ D LLGGG+E+ +IT Sbjct: 66 KGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAIT 125 Query: 182 ELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPD 241 E FGEFRTGK+QL HTL VT Q+P G GK ++IDTE TFRP RL IA RF +D D Sbjct: 126 EAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHD 185 Query: 242 DALNNVAYARAYNADHQLRLLDAAAQMMSE--SRFSLIVVDSVMALYRTDFSGRGELSAR 299 L+NV YARAY ++HQ+ LLD A E F L+++DS+MAL+R DFSGRGEL+ R Sbjct: 186 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAER 245 Query: 300 QMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLG 359 Q LA+ + LQ++++++ VAV VTNQ+ A M F DPKKPIGG+I+AH+STTR+ Sbjct: 246 QQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRIS 305 Query: 360 FKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPRE 397 +KG+G R+ K+ DSP +PE E FAI G+GD +E Sbjct: 306 LRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE 343 >1PZN-A nrPDB Length = 349 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 149/349 (42%), Positives = 224/349 (64%), Gaps = 16/349 (4%) Query: 59 EQAEAQGEMEDEAYDEAALGSFVP------IEKLQ-VNGITMADVKKLRESGLHTAEAVA 111 E+ + E E+ ++ A + I ++ + G+ A +KLRE+G T EA+A Sbjct: 4 EEVKEIDEFEELGFEPATEETPKKKKKEKIIRSIEDLPGVGPATAEKLREAGYDTLEAIA 63 Query: 112 YAPRKDLLEIKGISEAKADKLLNEAARLVPMG-FVTAADFHMRRSELICLTTGSKNLDTL 170 A +L E+ GISE A K++ A + +G F+ A ++ +R+ + ++TGSK+LD L Sbjct: 64 VASPIELKEVAGISEGTALKIIQAARKAANLGTFMRADEYLKKRATIGRISTGSKSLDKL 123 Query: 171 LGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLV 230 LGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + GG G ++IDTE TFRP R+ Sbjct: 124 LGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVIWIDTENTFRPERIR 183 Query: 231 SIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSE-----SRFSLIVVDSVMAL 285 IAQ GLDPD+ L ++ ARA+N++HQ+ L+ A + E L++VDS+ + Sbjct: 184 EIAQNRGLDPDEVLKHIYVARAFNSNHQMLLVQQAEDKIKELLNTDRPVKLLIVDSLTSH 243 Query: 286 YRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPI 345 +R+++ GRG L+ RQ LAK + L RLA+ + +AV VTNQV A+ D AF DP +PI Sbjct: 244 FRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVQARPD---AFFGDPTRPI 300 Query: 346 GGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGD 394 GG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E VF+I E G+ D Sbjct: 301 GGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 349 >2B21-A nrPDB Length = 322 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 123/322 (38%), Positives = 187/322 (58%), Gaps = 14/322 (4%) Query: 84 EKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMG 143 + G+ + +KL E+G +A A +L +I+GISE A K++ A L +G Sbjct: 4 NLTDLPGVGPSTAEKLVEAGYIDFMKIATATVGELTDIEGISEKAAAKMIMGARDLCDLG 63 Query: 144 FVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQ 203 F + D +RS + L+T S LD++LGGG+E+ S+TE G F +GK+Q+ H V Q Sbjct: 64 FKSGIDLLKQRSTVWKLSTSSSELDSVLGGGLESQSVTEFAGVFGSGKTQIMHQSCVNLQ 123 Query: 204 IPLDIGGGE----------GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAY 253 P + E K +YIDTEGTFRP R++ +A+ G+D L+N ARAY Sbjct: 124 NPEFLFYDEEAVSKGEVAQPKAVYIDTEGTFRPERIMQMAEHAGIDGQTVLDNTFVARAY 183 Query: 254 NADHQLRLLDAAAQMMSES-RFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQR 312 N+D Q+ + ++ E L+V+DS+ + +R +++GRG+L+ RQ L + M L + Sbjct: 184 NSDMQMLFAEKIEDLIQEGNNIKLVVIDSLTSTFRNEYTGRGKLAERQQKLGRHMATLNK 243 Query: 313 LADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKV 372 LAD F V+VTNQV A+ D AF ++ IGG+I+ H++T R +KGKG +R+ K+ Sbjct: 244 LADLFNCVVLVTNQVSAKPD---AFFGMAEQAIGGHIVGHAATFRFFVRKGKGDKRVAKL 300 Query: 373 VDSPCLPEAECVFAIYEDGVGD 394 DSP LP+AE +F I E G+ D Sbjct: 301 YDSPHLPDAEAIFRITEKGIQD 322 >2ZUB-A nrPDB Length = 324 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 131/312 (41%), Positives = 196/312 (62%), Gaps = 4/312 (1%) Query: 87 QVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVT 146 + GI+ + KL E+G + E +A A +DL GI + A K++ EA + + F T Sbjct: 16 DLPGISQTVINKLIEAGYSSLETLAVASPQDLSVAAGIPLSTAQKIIKEARDALDIRFKT 75 Query: 147 AADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPL 206 A + R + ++TGS+ LD LL GG+ET ++TE FGEF +GK+QLCH L+V Q+P Sbjct: 76 ALEVKKERMNVKKISTGSQALDGLLAGGIETRTMTEFFGEFGSGKTQLCHQLSVNVQLPP 135 Query: 207 DIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAA 266 + GG GK +YIDTEGTFR R+ ++A+ GLD D+ +NN+ Y RA N DHQ+ ++D Sbjct: 136 EKGGLSGKAVYIDTEGTFRWERIENMAKALGLDIDNVMNNIYYIRAINTDHQIAIVDDLQ 195 Query: 267 QMMS-ESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTN 325 +++S + LIVVDSV + +R ++ GR L+ RQ L K + L RLA+ + +AV++TN Sbjct: 196 ELVSKDPSIKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLTRLAEVYDIAVIITN 255 Query: 326 QVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVF 385 QV+A+ D F DP +GG+ + H R+ KK +G +R+ +VVD+P LPE E VF Sbjct: 256 QVMARPD---MFYGDPTVAVGGHTLYHVPGIRIQLKKSRGNRRIARVVDAPHLPEGEVVF 312 Query: 386 AIYEDGVGDPRE 397 A+ E+G+ D E Sbjct: 313 ALTEEGIRDAEE 324 >3EWA-A nrPDB Length = 322 Score = 377 bits (968), Expect = e-105, Method: Composition-based stats. Identities = 117/319 (36%), Positives = 182/319 (57%), Gaps = 14/319 (4%) Query: 87 QVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVT 146 ++ G+ + KL E G +A A +L +I+GISE A K++ A L +GF + Sbjct: 7 ELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKS 66 Query: 147 AADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPL 206 + +R + L+TGS LDT+L GG+E+ S+TE G F +GK+Q+ H V Q+ Sbjct: 67 GVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQMRE 126 Query: 207 DIGG----------GEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNAD 256 I K +YIDTEGTFRP R+V +A+ G+D L+N ARAYN+D Sbjct: 127 KIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQMAEGAGIDGQTVLDNTFVARAYNSD 186 Query: 257 HQLRLLDAAAQMMSES-RFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLAD 315 Q+ + ++ L+++DS+ + +R +F+GRG+L+ RQ L + M L +LAD Sbjct: 187 MQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLAD 246 Query: 316 QFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDS 375 + V+VTNQV A+ D A+ ++ IGG+++ H++T R +K KG +R+ K+ DS Sbjct: 247 LYNCIVLVTNQVAAKPD---AYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDS 303 Query: 376 PCLPEAECVFAIYEDGVGD 394 P LP++E VF I E G+ D Sbjct: 304 PHLPDSEAVFRITEKGIQD 322 >1N0W-A nrPDB Length = 243 Score = 347 bits (890), Expect = 6e-96, Method: Composition-based stats. Identities = 172/243 (70%), Positives = 208/243 (85%) Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 SE+I +TTGSK LD LL GG+ETGSITE+FGEFRTGK+Q+CHTLAVTCQ+P+D GGGEGK Sbjct: 1 SEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGK 60 Query: 215 CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRF 274 +YIDTEGTFRP RL+++A+R+GL D L+NVAYARA+N DHQ +LL A+ MM ESR+ Sbjct: 61 AMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRY 120 Query: 275 SLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGG 334 +L++VDS ALYRTD+SGRGELSARQMHLA+F+R L RLAD+FGVAVV+TNQVVAQVDG Sbjct: 121 ALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGA 180 Query: 335 MAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGD 394 F DPKKPIGGNI+AH+STTRL +KG+G R+CK+ DSPCLPEAE +FAI DGVGD Sbjct: 181 AMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 240 Query: 395 PRE 397 ++ Sbjct: 241 AKD 243 >6R3P-A nrPDB Length = 261 Score = 347 bits (889), Expect = 7e-96, Method: Composition-based stats. Identities = 135/258 (52%), Positives = 180/258 (69%), Gaps = 2/258 (0%) Query: 142 MGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVT 201 GF+TA ++ +R + +TTGS+ D LLGGG+E+ +ITE FGEFRTGK+QL HTL VT Sbjct: 4 PGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVT 63 Query: 202 CQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRL 261 Q+P G GK ++IDTE TFRP RL IA RF +D D L+NV YARAY ++HQ+ L Sbjct: 64 AQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMEL 123 Query: 262 LDAAAQMMSE--SRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGV 319 LD A E F L+++DS+MAL+R DFSGRGEL+ RQ LA+ + LQ++++++ V Sbjct: 124 LDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNV 183 Query: 320 AVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLP 379 AV VTNQ+ A M F DPKKPIGG+I+AH+STTR+ +KG+G R+ K+ DSP +P Sbjct: 184 AVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMP 243 Query: 380 EAECVFAIYEDGVGDPRE 397 E E FAI G+GD +E Sbjct: 244 ENEATFAITAGGIGDAKE 261 >4DC9-A nrPDB Length = 266 Score = 330 bits (846), Expect = 6e-91, Method: Composition-based stats. Identities = 106/266 (39%), Positives = 160/266 (60%), Gaps = 14/266 (5%) Query: 140 VPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 + +GF + D +RS + L+T S LD++LGGG+E+ S+TE G F +GK+Q+ H Sbjct: 4 MDLGFKSGIDLLKQRSTVWKLSTSSSELDSVLGGGLESQSVTEFAGVFGSGKTQIMHQSC 63 Query: 200 VTCQIPLDIGGGE----------GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAY 249 V Q P + E K +YIDTEGTFRP R++ +A+ G+D L+N Sbjct: 64 VNLQNPEFLFYDEEAVSKGEVAQPKAVYIDTEGTFRPERIMQMAEHAGIDGQTVLDNTFV 123 Query: 250 ARAYNADHQLRLLDAAAQMMSES-RFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMR 308 ARAYN+D Q+ + ++ E L+V+DS+ + +R +++GRG+L+ RQ L + M Sbjct: 124 ARAYNSDMQMLFAEKIEDLIQEGNNIKLVVIDSLTSTFRNEYTGRGKLAERQQKLGRHMA 183 Query: 309 ALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQR 368 L +LAD F V+VTNQV A+ D AF ++ IGG+I+ H++T R +KGKG +R Sbjct: 184 TLNKLADLFNCVVLVTNQVSAKPD---AFFGMAEQAIGGHIVGHAATFRFFVRKGKGDKR 240 Query: 369 LCKVVDSPCLPEAECVFAIYEDGVGD 394 + K+ DSP LP+AE +F I E G+ D Sbjct: 241 VAKLYDSPHLPDAEAIFRITEKGIQD 266 >5KDD-A nrPDB Length = 231 Score = 313 bits (803), Expect = 6e-86, Method: Composition-based stats. Identities = 124/245 (50%), Positives = 173/245 (70%), Gaps = 20/245 (8%) Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 + + ++TGSK+LD LLGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + GG G Sbjct: 2 ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGS 61 Query: 215 CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSES-- 272 +YIDTE TFRP RL IAQ GLDPD+ L+NVAYARA+N++HQ++LL A+ MM ES Sbjct: 62 AMYIDTENTFRPERLREIAQNRGLDPDEVLDNVAYARAFNSNHQMQLLYQASAMMVESLN 121 Query: 273 ---RFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVA 329 + L++VDS+ + +R+++ GRG L+ RQ LA+F+R L RLA++F +AV VTNQV A Sbjct: 122 TDRPYKLLIVDSLTSHFRSEYIGRGALAERQQKLARFLRMLHRLANEFDIAVFVTNQVQA 181 Query: 330 QVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYE 389 GG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E VF+I E Sbjct: 182 N---------------GGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITE 226 Query: 390 DGVGD 394 G+ D Sbjct: 227 KGIED 231 >5LB2-A nrPDB Length = 230 Score = 306 bits (784), Expect = 9e-84, Method: Composition-based stats. Identities = 115/245 (46%), Positives = 166/245 (67%), Gaps = 21/245 (8%) Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 + + ++TGSK+LD LLGGG+ET +ITE+FGEF +GK+QL HTLAV Q+P + GG G Sbjct: 2 ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGS 61 Query: 215 CLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSE--- 271 ++IDTE TFRP R+ IAQ GLDPD+ L ++AYARA+N++HQ+ L+ A+ M+ E Sbjct: 62 VMWIDTENTFRPERIREIAQNRGLDPDEVLKHIAYARAFNSNHQMLLVQQASAMIKELLN 121 Query: 272 --SRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVA 329 L++VDS+ + +R+++ GRG L+ RQ LAK + L RLA+ + +AV VTNQV A Sbjct: 122 TDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVQA 181 Query: 330 QVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYE 389 GG+I+AHS+T R+ +KGKG +R+ +++D+P LPE E VF+I E Sbjct: 182 ----------------GGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITE 225 Query: 390 DGVGD 394 G+ D Sbjct: 226 KGIED 230 >1MO5-A nrPDB Length = 350 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 103/259 (39%), Gaps = 40/259 (15%) Query: 152 MRRSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGG 210 R + + TGS LD LG GG+ G + E++G +GK+ + Q Sbjct: 33 EARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ------A 86 Query: 211 GEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMS 270 G +ID E P A++ G+D D L D + L+ A ++ Sbjct: 87 AGGVAAFIDAEHALDP----DYAKKLGVDTDSLL-------VSQPDTGEQALEIADMLIR 135 Query: 271 ESRFSLIVVDSVMALY-RTDFSGR-----GELSARQMHLAKFMRALQRLADQFGVAVVVT 324 ++V+DSV AL R + G L AR M A +R + + G + Sbjct: 136 SGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQA--LRKMTGALNNSGTTAIFI 193 Query: 325 NQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK---------GKGCQRLCKVVDS 375 NQ+ ++ G+ F P+ GG + ++ R+ ++ G + KVV + Sbjct: 194 NQLRDKI--GVMFG-SPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKN 250 Query: 376 PCL-PEAECVFAI-YEDGV 392 CL P + F I Y G+ Sbjct: 251 KCLAPFKQAEFDILYGKGI 269 >1UBG-A nrPDB Length = 349 Score = 205 bits (522), Expect = 3e-53, Method: Composition-based stats. Identities = 63/257 (24%), Positives = 102/257 (39%), Gaps = 40/257 (15%) Query: 154 RSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGE 212 R + + TGS +LD LG GG+ G + E++G +GK+ + Q Sbjct: 36 RQPISVIPTGSISLDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ------AAG 89 Query: 213 GKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSES 272 G +ID E P A++ G+D D L D + L+ A ++ Sbjct: 90 GIAAFIDAEHALDPE----YAKKLGVDTDSLL-------VSQPDTGEQALEIADMLVRSG 138 Query: 273 RFSLIVVDSVMALY-RTDFSGR-----GELSARQMHLAKFMRALQRLADQFGVAVVVTNQ 326 +IV+DSV AL R + G L AR M A +R + + G + NQ Sbjct: 139 ALDIIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQA--LRKMTGALNNSGTTAIFINQ 196 Query: 327 VVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK---------GKGCQRLCKVVDSPC 377 + ++ G+ F P+ GG + ++ RL ++ G + KVV + Sbjct: 197 LREKI--GVMFG-SPETTTGGKALKFYASVRLDVRRIETLKDGTDAVGNRTRVKVVKNKV 253 Query: 378 LPEA-ECVFAI-YEDGV 392 P + F I Y G+ Sbjct: 254 SPPFKQAEFDILYGQGI 270 >3HR8-A nrPDB Length = 356 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 68/289 (23%), Positives = 114/289 (39%), Gaps = 44/289 (15%) Query: 126 EAKADKLLNEAARLVPMGFVTAADFH----MRRSELICLTTGSKNLDTLLG-GGVETGSI 180 E + +L +A + + F + + + + TGS +D G GG G I Sbjct: 4 EKQKKSVLEKALKRIEENFGKGSIMILGDETQVQPVEVIPTGSLAIDIATGVGGYPRGRI 63 Query: 181 TELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDP 240 E+FG+ +GK+ L Q G +ID E PV A+ G+D Sbjct: 64 VEIFGQESSGKTTLALHAIAEAQ------KMGGVAAFIDAEHALDPV----YAKNLGVDL 113 Query: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALY-RTDFSG-----RG 294 L DH + L+ +++ LIVVDSV AL R + G + Sbjct: 114 KSLLI-------SQPDHGEQALEIVDELVRSGVVDLIVVDSVAALVPRAEIEGAMGDMQV 166 Query: 295 ELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSS 354 L AR M A +R + ++ V+ TNQ+ ++ G+ F P+ GG + + Sbjct: 167 GLQARLMSQA--LRKIAGSVNKSKAVVIFTNQIRMKI--GVMFG-SPETTTGGLALKFYA 221 Query: 355 TTRLGFKKGKGCQR---------LCKVVDSPCLPEAEC--VFAIYEDGV 392 T R+ ++G+ + K+V + P + + IY G+ Sbjct: 222 TMRMEVRRGEPIKEGKDVIGNVISVKIVKNKVAPPFKTAQTYIIYGKGI 270 >1XMS-A nrPDB Length = 356 Score = 196 bits (497), Expect = 2e-50, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 114/258 (44%), Gaps = 40/258 (15%) Query: 153 RRSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGG 211 R ++ ++TGS +LD LG GG+ G I E++G +GK+ L + Q Sbjct: 37 RSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQ------RE 90 Query: 212 EGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSE 271 C +ID E P+ A++ G+D D N+ ++ + L + DA A Sbjct: 91 GKTCAFIDAEHALDPI----YARKLGVDID----NLLCSQPDTGEQALEICDALA---RS 139 Query: 272 SRFSLIVVDSVMAL-YRTDFSGR-GE----LSARQMHLAKFMRALQRLADQFGVAVVVTN 325 +IVVDSV AL + + G G+ L+AR M A MR L Q ++ N Sbjct: 140 GAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQA--MRKLAGNLKQSNTLLIFIN 197 Query: 326 QVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK---------GKGCQRLCKVVDSP 376 Q+ ++ G+ F +P+ GGN + ++ RL ++ G + KVV + Sbjct: 198 QIRMKI--GVMFG-NPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNK 254 Query: 377 -CLPEAECVFAI-YEDGV 392 P + F I Y +G+ Sbjct: 255 IAAPFKQAEFQILYGEGI 272 >2CVH-A nrPDB Length = 220 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 117/239 (48%), Gaps = 22/239 (9%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK-CLYI 218 L+TG+K+LD+LLGGG G +T+++G + +GK+ L G GK Y+ Sbjct: 2 LSTGTKSLDSLLGGGFAPGVLTQVYGPYASGKTTLALQ----------TGLLSGKKVAYV 51 Query: 219 DTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIV 278 DTEG F P RLV +A+ GL+P++AL+ + Q R++ + + + +S F+L+V Sbjct: 52 DTEGGFSPERLVQMAETRGLNPEEALSRFILFTPSDFKEQRRVIGSLKKTV-DSNFALVV 110 Query: 279 VDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFN 338 VDS+ A YR + + G ++ L++ ++ L +A + + V+V NQV Sbjct: 111 VDSITAHYRAEENRSGLIAE----LSRQLQVLLWIARKHNIPVIVINQVHFD-SRTEMTK 165 Query: 339 PDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEA-ECVFAIYEDGVGDPR 396 P ++ +G RL K K R+ + PE F I E G+ D Sbjct: 166 PVAEQTLGYRC---KDILRLD-KLPKPGLRVAVLERHRFRPEGLMAYFRITERGIEDVE 220 >5JRJ-A nrPDB Length = 351 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 69/255 (27%), Positives = 115/255 (45%), Gaps = 40/255 (15%) Query: 155 SELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEG 213 E+ ++TGS LD LG GG+ G + E++G +GK+ L T Q ++ G Sbjct: 42 EEIQAVSTGSLGLDIALGIGGLPRGRVIEIYGPESSGKTTL------TLQSIAEMQKLGG 95 Query: 214 KCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESR 273 C +ID E V+ AQ+ G++ LN++ ++ + L + DA ++ Sbjct: 96 TCAFIDAEHALD----VTYAQKLGVN----LNDLLISQPDTGEQALEICDA---LVRSGA 144 Query: 274 FSLIVVDSVMAL-YRTDFSG-RGE----LSARQMHLAKFMRALQRLADQFGVAVVVTNQV 327 LIVVDSV AL + + G G+ L AR M A +R L ++ V+ NQ+ Sbjct: 145 VDLIVVDSVAALTPKAEIEGDMGDSLPGLQARLMSQA--LRKLTGSINRTNTTVIFINQI 202 Query: 328 VAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCL--------- 378 ++ G+ F +P+ GGN + ++ RL ++ + +V+ S Sbjct: 203 RMKI--GVMFG-NPETTTGGNALKFYASVRLDIRRTGSIKSGDEVIGSETKVKVVKNKVA 259 Query: 379 -PEAECVFAI-YEDG 391 P E F I Y +G Sbjct: 260 PPFREAHFDILYGEG 274 >1XP8-A nrPDB Length = 366 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 41/259 (15%) Query: 152 MRRSELICLTTGSKNLDTLLG-GGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGG 210 + ++ ++TGS +LD LG GG+ G ITE++G GK+ L + Q Sbjct: 47 ESKLDVQVVSTGSLSLDLALGVGGIPRGRITEIYGPESGGKTTLALAIVAQAQ------K 100 Query: 211 GEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMS 270 G C +ID E PV A+ G++ D+ L ++ N + L +++ ++ Sbjct: 101 AGGTCAFIDAEHALDPV----YARALGVNTDELL----VSQPDNGEQALEIMEL---LVR 149 Query: 271 ESRFSLIVVDSVMAL-YRTDFSG-RGE----LSARQMHLAKFMRALQRLADQFGVAVVVT 324 ++VVDSV AL R + G G+ L AR M A +R L + + G A + Sbjct: 150 SGAIDVVVVDSVAALTPRAEIEGDMGDSLPGLQARLMSQA--LRKLTAILSKTGTAAIFI 207 Query: 325 NQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKK----------GKGCQRLCKVVD 374 NQV ++ G+ + +P+ GG + ++ RL +K K V Sbjct: 208 NQVREKI--GVMYG-NPETTTGGRALKFYASVRLDVRKIGQPTKVGNDAVANTVKIKTVK 264 Query: 375 SPC-LPEAECVFA-IYEDG 391 + P E A +Y G Sbjct: 265 NKVAAPFKEVELALVYGKG 283 >2W0M-A nrPDB Length = 235 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 35/199 (17%), Positives = 72/199 (36%), Gaps = 33/199 (16%) Query: 156 ELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKC 215 + L+TG + D L+ GG+ G L GE TGK+ C Sbjct: 1 MVSRLSTGILDFDKLIQGGIPQGFFIALTGEPGTGKTIFSLHFIA------KGLRDGDPC 54 Query: 216 LYIDTEGTFRPVRLVSIAQRFGLDPDD-------ALNNVAYARAYNADHQLRLLDAAAQM 268 +Y+ TE + ++ A++F D ++ ++ + + + Sbjct: 55 IYVTTEESRD--SIIRQAKQFNWDFEEYIEKKLIIIDALMKEKEDQWSLVNLTPEELVNK 112 Query: 269 MSESRFSL------IVVDSVMALYRTDFSGRGELSARQMHLAKFMR-ALQRLADQFGVAV 321 + E++ L +V+DSV AL+ +A+ + L+R+ +++ + Sbjct: 113 VIEAKQKLGYGKARLVIDSVSALFLDK-----------PAMARKISYYLKRVLNKWNFTI 161 Query: 322 VVTNQVVAQVDGGMAFNPD 340 T+Q F + Sbjct: 162 YATSQYAITTSQAFGFGVE 180 >2Q6T-A nrPDB Length = 444 Score = 54.7 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 58/262 (22%), Positives = 100/262 (38%), Gaps = 27/262 (10%) Query: 95 DVKKLRESGLHTAEAVAYAPRKDLLEI-----KGISEAKADKLLNEAA---RLVPMGFVT 146 +++L ++ A +AY L EI K I E K EA LV F Sbjct: 111 TLRRLIQAA-GEAMRLAYEEAGSLDEILDTAGKKILEVALTKTDTEARPMRELVHETFEH 169 Query: 147 AADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPL 206 + E+ + TG K LD L+ G + GS+ + GK+ T+A + Sbjct: 170 IEALFQNKGEVAGVRTGFKELDQLI-GTLGPGSLNIIAARPAMGKTAFALTIAQNAALKE 228 Query: 207 DIGGGEGKCLYIDTEGTFR-----------PVRLVSIAQR---FGLDPDDALNNVAYARA 252 +G G + T R VRL + R +D L+ Sbjct: 229 GVGVGIYSLEMPAAQLTLRMMCSEARIDMNRVRLGQLTDRDFSRLVDVASRLSEAPIYID 288 Query: 253 YNAD-HQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQ 311 D + + A +++S+++ LI++D + + GE RQ +A R L+ Sbjct: 289 DTPDLTLMEVRARARRLVSQNQVGLIIIDYLQLMSGPGSGKSGE--NRQQEIAAISRGLK 346 Query: 312 RLADQFGVAVVVTNQVVAQVDG 333 LA + G+ ++ +Q+ V+ Sbjct: 347 ALARELGIPIIALSQLSRAVEA 368 >2DR3-A nrPDB Length = 247 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 44/257 (17%), Positives = 81/257 (31%), Gaps = 52/257 (20%) Query: 159 CLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYI 218 + TG +D +L GG+ ++ L G TGK+ + Q + +Y+ Sbjct: 4 RVKTGIPGVDEILHGGIPERNVVLLSGGPGTGKT------IFSQQFLWNGLKMGEPGIYV 57 Query: 219 DTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQ------------------LR 260 E PV++ +FG D +A Sbjct: 58 ALEE--HPVQVRQNMAQFGWDVKPYEEKGMFAMVDAFTAGIGKSKEYEKYIVHDLTDIRE 115 Query: 261 LLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVA 320 ++ Q + + +VVDSV LY ++ M + ++ L+R+ G Sbjct: 116 FIEVLRQAIRDINAKRVVVDSVTTLY---------INKPAMARSIILQ-LKRVLAGTGCT 165 Query: 321 VVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHS--STTRLGFKKGKGCQRLCKVV---DS 375 + +QV ++ GG + H RL + G + +V Sbjct: 166 SIFVSQVSV-----------GERGFGGPGVEHGVDGIIRLDLDEIDGELKRSLIVWKMRG 214 Query: 376 PCLPEAECVFAIYEDGV 392 F I + G+ Sbjct: 215 TSHSMRRHPFDITDKGI 231 >5JWO-A nrPDB Length = 247 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 96/259 (37%), Gaps = 32/259 (12%) Query: 154 RSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEG 213 ++E+ + T + D + GG+ G+ T + G TGK+ + G Sbjct: 8 KAEVKKIPTMIEGFDDISHGGLPQGATTLVSGTSGTGKTLFAVQFLYNGITIFNEPG--- 64 Query: 214 KCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNN---VAYARAYNADHQL--------RLL 262 +++ E + P ++ A FG + ++ + + D Q L+ Sbjct: 65 --IFVTFEES--PQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALI 120 Query: 263 DAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVV 322 + + + + + + +DSV A+++ + + LA + L GV + Sbjct: 121 ERIQYAIRKYKATRVSIDSVTAVFQ-QYDAASVVRREIFRLAFRLAQL-------GVTTI 172 Query: 323 VTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAE 382 +T + V + F + I+ + L ++ + + K+ + + + E Sbjct: 173 MTTERVDEYGPVARFGVEEFVSDNVVILRNV----LEGERRRRTVEILKLRGTTHM-KGE 227 Query: 383 CVFAIYED-GVGDPREEDE 400 F I + D +++D+ Sbjct: 228 YPFTINNGINIFDYKDDDD 246 >5LKM-A nrPDB Length = 452 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 45/239 (18%), Positives = 90/239 (37%), Gaps = 36/239 (15%) Query: 156 ELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKC 215 + T + + +LGGGV GS+ + G+ GKS L ++ G Sbjct: 66 NVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSQV-------GTV 118 Query: 216 LYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFS 275 LY+ E + + ++L A+R G D D YA + ++ + A + + Sbjct: 119 LYVSGEESAQQIKLR--AERLG-DIDSEF--YLYA-----ETNMQSVRAEVERIQP---D 165 Query: 276 LIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGM 335 +++DS+ + + SG + + + L +LA +A+ + V + Sbjct: 166 FLIIDSIQTIMSPEISG---VQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE----- 217 Query: 336 AFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQ-RLCKVVDSPCLPEAE-CVFAIYEDGV 392 G ++ H T L F+ + R+ + V + E +F + G+ Sbjct: 218 ------GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGL 270 >4O0M-A nrPDB Length = 524 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 32/200 (16%), Positives = 72/200 (36%), Gaps = 26/200 (13%) Query: 152 MRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGG 211 +E+ + T + D + GG+ G T + G TGK+ + G Sbjct: 14 QSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPG- 72 Query: 212 EGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNN---VAYARAYNADHQL--------R 260 +++ E + P ++ A FG + ++ + + D Q Sbjct: 73 ----IFVTFEES--PQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSA 126 Query: 261 LLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVA 320 L++ + + + + + +DSV A+++ + + LA ++ L GV Sbjct: 127 LIERIQYAIRKYKATRVSIDSVTAVFQ-QYDAASVVRREIFRLAFRLKQL-------GVT 178 Query: 321 VVVTNQVVAQVDGGMAFNPD 340 ++T + V + F + Sbjct: 179 TIMTTERVDEYGPVARFGVE 198 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 74/188 (39%), Gaps = 26/188 (13%) Query: 144 FVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQ 203 F A +RS + +++G K LD + GGG SI G TGK+ L Sbjct: 247 FPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLL-------VS 299 Query: 204 IPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDA----LNNVAYARAYNA--DH 257 L+ G +G+ + R + A +G+D ++ L + A +A + Sbjct: 300 KFLETGCQQGERALLFAYEESRAQLSRN-ASSWGIDFEELERRGLLRIICAYPESAGLED 358 Query: 258 QLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQF 317 L+++ + SR + +DS+ AL R G + RQ F+ + A Q Sbjct: 359 HLQIIKSEIADFKPSRVA---IDSLSALAR----GVSNNAFRQ-----FVIGVTGFAKQE 406 Query: 318 GVAVVVTN 325 + TN Sbjct: 407 EITGFFTN 414 >4YDS-A nrPDB Length = 228 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 38/205 (18%), Positives = 77/205 (37%), Gaps = 29/205 (14%) Query: 160 LTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYID 219 ++TG+ +LD L GG+ + + G+ TGKS L + + G I Sbjct: 3 ISTGNDDLDRRL-GGIPYPASIMIEGDHGTGKSVLSAQFVLGFLLSDKKGYV------IT 55 Query: 220 TEGTFRPVRLVSIAQRFGLDPDDALNNVAYARA------YNADHQLRLLDAAAQMMSESR 273 TE T + + + L P + A +N+ ++LD + Sbjct: 56 TEQTTKDYLIKMKEIKIDLIPYFIRGKLRIAPLNTKKFNWNSSLAEKILDVIVNFIRSKN 115 Query: 274 FSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTN------QV 327 IV+DS+ L FS ++ L +FM+ ++ L + + + + ++ Sbjct: 116 IDFIVIDSLSIL--AAFS-------KEKQLLQFMKDIRVLVNTGKMILFTIHPDTFDEEM 166 Query: 328 VAQVDGGM-AFNPDPKKPIGGNIMA 351 +++ + + IGG + Sbjct: 167 KSKITSIVDVYLKLSAATIGGRRVK 191 >3S1A-A nrPDB Length = 525 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 38/259 (14%), Positives = 93/259 (35%), Gaps = 31/259 (11%) Query: 145 VTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQI 204 +T+ + + + + T + D + GG+ G T + G TGK+ I Sbjct: 6 MTSPNNNSEHQAIAKMRTMIEGFDDISHGGLPIGRSTLVSGTSGTGKTLFSIQFLYNGII 65 Query: 205 PLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNN---VAYARAYNADHQL-- 259 D G +++ E T P ++ A+ FG D ++ + + + Q Sbjct: 66 EFDEPG-----VFVTFEET--PQDIIKNARSFGWDLAKLVDEGKLFILDASPDPEGQEVV 118 Query: 260 ------RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRL 313 L++ + + R + +DSV ++++ + + L ++ + Sbjct: 119 GGFDLSALIERINYAIQKYRARRVSIDSVTSVFQ-QYDASSVVRRELFRLVARLKQI--- 174 Query: 314 ADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVV 373 G V+T + + + + + I+ + L ++ + + K+ Sbjct: 175 ----GATTVMTTERIEEYGPIARYGVEEFVSDNVVILRNV----LEGERRRRTLEILKLR 226 Query: 374 DSPCLPEAECVFAIYEDGV 392 + + + E F I + G+ Sbjct: 227 GTSHM-KGEYPFTITDHGI 244 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 95/257 (36%), Gaps = 35/257 (13%) Query: 117 DLLEIKGISEAKAD---KLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGG 173 ++L+++G S K + + + + P+G + +RS + +++G LD + GG Sbjct: 221 EILKLRGTSHMKGEYPFTITDHGINIFPLGAMR----LTQRSSNVRVSSGVVRLDEMCGG 276 Query: 174 GVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIA 233 G SI G TGK+ L + L+ E +L+ A Sbjct: 277 GFFKDSIILATGATGTGKTLLVSRFVENACANKERA-----ILFAYEE---SRAQLLRNA 328 Query: 234 QRFGLDPDDA----LNNVAYARAYNA---DHQLRLLDAAAQMMSESRFSLIVVDSVMALY 286 +G+D ++ L + A +A DH L +++ + + I +DS+ AL Sbjct: 329 YSWGMDFEEMERQNLLKIVCAYPESAGLEDH----LQIIKSEINDFKPARIAIDSLSALA 384 Query: 287 RTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIG 346 R G + RQ F+ + A Q + + TN + + ++ Sbjct: 385 R----GVSNNAFRQ-----FVIGVTGYAKQEEITGLFTNTSDQFMGAHSITDSHIEEITD 435 Query: 347 GNIMAHSSTTRLGFKKG 363 I+ R + Sbjct: 436 TIILLQYVEIRGEMSRA 452 >4WIA-A nrPDB Length = 233 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 12/142 (8%) Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVT-CQIPLDIGGGEG 213 EL + +LD +GGG+ GS+ + GE TGKS LC LA Q Sbjct: 4 MELARIDLSRDDLDKRIGGGIPHGSLIIIEGEESTGKSVLCQRLAYGFLQNRY------- 56 Query: 214 KCLYIDTEGT----FRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMM 269 Y+ T+ T + + ++ + L L Y + + L + Sbjct: 57 SVTYVSTQLTTLEFIKQMNSLNYSINKKLLSGALLYIPVYPLIADNKKKDGFLKKVMETR 116 Query: 270 SESRFSLIVVDSVMALYRTDFS 291 + +I+ DS+ AL D S Sbjct: 117 AFYEKDVIIFDSISALIANDAS 138 >4TLD-A nrPDB Length = 253 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 38/259 (14%), Positives = 93/259 (35%), Gaps = 31/259 (11%) Query: 145 VTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQI 204 +T+ + + + + T + D + GG+ G T + G TGK+ I Sbjct: 6 MTSPNNNSEHQAIAKMRTMIEGFDDISHGGLPIGRSTLVSGTSGTGKTLFSIQFLYNGII 65 Query: 205 PLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNN---VAYARAYNADHQL-- 259 D G +++ E T P ++ A+ FG D ++ + + + Q Sbjct: 66 EFDEPG-----VFVTFEET--PQDIIKNARSFGWDLAKLVDEGKLFILDASPDPEGQEVV 118 Query: 260 ------RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRL 313 L++ + + R + +DSV ++++ + + L ++ + Sbjct: 119 GGFDLSALIERINYAIQKYRARRVSIDSVTSVFQ-QYDAPSVVRRELFRLVARLKQI--- 174 Query: 314 ADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVV 373 G V+T + + + + + I+ + L ++ + + K+ Sbjct: 175 ----GATTVMTTERIEEYGPIARYGVEEFVSDNVVILRNV----LEGERRRRTLEILKLR 226 Query: 374 DSPCLPEAECVFAIYEDGV 392 + + + E F I + G+ Sbjct: 227 GTSHM-KGEYPFTITDHGI 244 >5MS0-M nrPDB Length = 497 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%) Query: 74 EAALGSFVPIE-KLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKL 132 + +LG P + L + G+ KL G+ T E +A DL +I+G+++ KA L Sbjct: 424 QESLGDNKPADDLLNLEGVDRDLAFKLAARGVCTLEDLAEQGIDDLADIEGLTDEKAGAL 483 Query: 133 LNEAARLVPMG 143 + A + G Sbjct: 484 IMAARNICWFG 494 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 10/128 (7%) Query: 23 STVPADLSQSVVDGNGNGSSEDIEATNGSG----DGGGLQEQAEAQG------EMEDEAY 72 + PAD++ VVD + + +EA N + +G ++ ++ G ++D Sbjct: 289 AMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQA 348 Query: 73 DEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKL 132 A + I L E G T E +AY P K+LLEI+G+ E + L Sbjct: 349 KHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDEPTVEAL 408 Query: 133 LNEAARLV 140 A + Sbjct: 409 RERAKNAL 416 >5HM5-A nrPDB Length = 854 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 42/102 (41%), Gaps = 9/102 (8%) Query: 85 KLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLE-IKGISEAKADKLLNEAARLVPMG 143 L + G+ +++ E+ + E +A ++L E ++G+ E A++++ A V Sbjct: 624 LLNIEGVGPKLAERILEAVDYDLERLASLNPEELAEKVEGLGEELAERVVYAARERVESR 683 Query: 144 FVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFG 185 + R E + L+ +G G + E FG Sbjct: 684 RKSGRQ--ERSEEEWK-----EWLERKVGEGRAR-RLIEYFG 717 >5LM7-A nrPDB Length = 428 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 10/128 (7%) Query: 23 STVPADLSQSVVDGNGNGSSEDIEATNGSG----DGGGLQEQAEAQG------EMEDEAY 72 + PAD++ VVD + + +EA N + +G ++ ++ G ++D Sbjct: 289 AMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQA 348 Query: 73 DEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKL 132 A + I L E G T E +AY P K+LLEI+G+ E + L Sbjct: 349 KHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDEPTVEAL 408 Query: 133 LNEAARLV 140 A + Sbjct: 409 RERAKNAL 416 >5LM9-A nrPDB Length = 329 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 10/128 (7%) Query: 23 STVPADLSQSVVDGNGNGSSEDIEATNGSG----DGGGLQEQAEAQG------EMEDEAY 72 + PAD++ VVD + + +EA N + +G ++ ++ G ++D Sbjct: 190 AMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQA 249 Query: 73 DEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKL 132 A + I L E G T E +AY P K+LLEI+G+ E + L Sbjct: 250 KHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDEPTVEAL 309 Query: 133 LNEAARLV 140 A + Sbjct: 310 RERAKNAL 317 >3CCJ-Y nrPDB Length = 241 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 28/56 (50%) Query: 84 EKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARL 139 E ++G+ + + LRE+G + E V A + L ++ GI A A ++ + L Sbjct: 16 ELTDISGVGPSKAESLREAGFESVEDVRGADQSALADVSGIGNALAARIKADVGGL 71 >2R6A-A nrPDB Length = 454 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 41/262 (15%), Positives = 86/262 (32%), Gaps = 38/262 (14%) Query: 95 DVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRR 154 + + G + + + +I +S+ K ++ + H R Sbjct: 121 TATSIAQDGYTREDEIDVLLDEADRKIMEVSQRKHSGAFKNIKDILVQTYDNIEMLHNRD 180 Query: 155 SELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTC------------ 202 E+ + TG LD + G + + + GK+ +A Sbjct: 181 GEITGIPTGFTELDRMTS-GFQRSDLIIVAARPSVGKTAFALNIAQNVATKTNENVAIFS 239 Query: 203 ------QIPLDIGGGEGKCLYIDTE----GTFRPVRLVSIAQRFGLDPDDALNNVAYARA 252 Q+ + + EG I+ + G P + G +L+N Sbjct: 240 LEMSAQQLVMRMLCAEGN---INAQNLRTGKLTPEDWGKLTMAMG-----SLSNAGIYID 291 Query: 253 YNADHQL-RLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSA-RQMHLAKFMRAL 310 ++ + ++ ES +IV+D + G G RQ +++ R+L Sbjct: 292 DTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQL-----IQGSGRSKENRQQEVSEISRSL 346 Query: 311 QRLADQFGVAVVVTNQVVAQVD 332 + LA + V V+ +Q+ V+ Sbjct: 347 KALARELEVPVIALSQLSRSVE 368 >5VQ9-D nrPDB Length = 432 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 57/171 (33%), Gaps = 26/171 (15%) Query: 179 SITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGL 238 + L G TGK+ LC LA I L G+ + I++ F Sbjct: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSK------------ 220 Query: 239 DPDDALNNVAYARAYNADHQLRLLDAAAQMMSE-SRFSLIVVDSVMALYRTDFSGRG--E 295 + + ++ ++ + +++D V +L + R E Sbjct: 221 -----------WFSESGKLVTKMFQKIQDLIDDKDALVFVLIDQVESLTAARNACRAGTE 269 Query: 296 LSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGMAFNPDPKKPIG 346 S + + + ++ V ++ T+ + ++D D K+ IG Sbjct: 270 PSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIG 320 >3B0X-A nrPDB Length = 575 Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 83 IEKLQVNGITMADVKKLRES-GLHTAEAVAYA-PRKDLLEIKGISEAKADKLLNEAA 137 +E ++V G+ + L E G+ + E + A R DL +KG +A+++ A Sbjct: 93 LEVMEVPGVGPKTARLLYEGLGIDSLEKLKAALDRGDLTRLKGFGPKRAERIREGLA 149 >2ZJ8-A nrPDB Length = 720 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 25/52 (48%) Query: 83 IEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLN 134 I +Q+ + + L SG + E ++ A ++LL+I+GI + + Sbjct: 646 IPLMQLPLVGRRRARALYNSGFRSIEDISQARPEELLKIEGIGVKTVEAIFK 697 >2V1U-A nrPDB Length = 387 Score = 34.3 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 30/162 (18%), Positives = 58/162 (35%), Gaps = 17/162 (10%) Query: 167 LDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRP 226 L L G + ++ L+G TGK+ + + + G K +Y++ P Sbjct: 35 LAPALRGEKPSNAL--LYGLTGTGKTAVARLVLRRLEARASSLGVLVKPIYVNARHRETP 92 Query: 227 VRLVS-IAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMAL 285 R+ S IA+ G+ V + + RL+ +++ +IV+D + Sbjct: 93 YRVASAIAEAVGV-------RVPFTGLSVGEVYERLVKRLSRL---RGIYIIVLDEID-- 140 Query: 286 YRTDFSGRGELSARQMHLAKFM--RALQRLADQFGVAVVVTN 325 + G +L R + + + R L V N Sbjct: 141 FLPKRPGGQDLLYRITRINQELGDRVWVSLVGITNSLGFVEN 182 >1HQM-A nrPDB Length = 313 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 69 DEAYDEAALGSFVPIEK-LQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEA 127 + + E + ++ L+ G++ + L+E G+ + A+ KDL I GI E Sbjct: 236 EVSKGEKRESAEEDLDLPLEELGLSTRVLHSLKEEGIESVRALLALNLKDLRNIPGIGER 295 Query: 128 KADKLLNEAAR 138 +++ A+ Sbjct: 296 SLEEIRQALAK 306 >2QZ4-A nrPDB Length = 262 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 41/128 (32%), Gaps = 12/128 (9%) Query: 171 LGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLV 230 LG V G++ L G GK+ L +A Q+P G I G R L Sbjct: 34 LGAKVPKGAL--LLGPPGCGKTLLAKAVATEAQVPFLAMAGAEFVEVIGGLGAARVRSLF 91 Query: 231 SIAQRFG--------LDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSV 282 A+ +D + + N + + L +M ++V + Sbjct: 92 KEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIV--L 149 Query: 283 MALYRTDF 290 + R D Sbjct: 150 ASTNRADI 157 >5G4G-A nrPDB Length = 721 Score = 32.4 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 91/249 (36%), Gaps = 46/249 (18%) Query: 84 EKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLV--P 141 + + V G+T+A L + T + + +I+ I E A ++L E +R+ Sbjct: 128 DNISVPGLTLAGQTGLLFKVVKTLPSKVPVEIGEETKIE-IREEPASEVLEEVSRISYED 186 Query: 142 MGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVT 201 +G ++ + + E+I L L LG G I L+G TGK+ + Sbjct: 187 IGGLS--EQLGKIREMIELPLKHPELFERLGITPPKGVI--LYGPPGTGKTLIA------ 236 Query: 202 CQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRL 261 R V S A ++ + ++ + Sbjct: 237 -----------------------RAVANESGANFLSINGPEIMSKYY-------GQSEQK 266 Query: 262 LDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAV 321 L E+ S+I +D + ++ +GE+ R +A+ + + + ++ V V Sbjct: 267 LREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRV--VAQLLTLMDGMKERGHVIV 324 Query: 322 V-VTNQVVA 329 + TN++ A Sbjct: 325 IGATNRIDA 333 >2UVV-A nrPDB Length = 358 Score = 32.0 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 9/91 (9%) Query: 73 DEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKG-ISEAKADK 131 DE ++ V GI +KL++ G++ + + ++KG I EAKA Sbjct: 174 DEEVKRLIRELDIADVPGIGNITAEKLKKLGIN---KLVDTLSIEFDKLKGMIGEAKAKY 230 Query: 132 LLNEAARLVPMGFVTAADFHMRRSELICLTT 162 L++ A T R + + T Sbjct: 231 LISLARDEYNEPIRTRV-----RKSIGRIVT 256 >4F4Z-B nrPDB Length = 361 Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 73 DEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKG-ISEAKADK 131 DE ++ V GI +KL++ G + + ++KG I EAKA Sbjct: 168 DEEVKRLIRELDIADVPGIGNITAEKLKKLG---INKLVDTLSIEFDKLKGMIGEAKAKY 224 Query: 132 LLNEAAR 138 L++ A Sbjct: 225 LISLARD 231 >5M32-h nrPDB Length = 355 Score = 31.6 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 53/331 (16%), Positives = 110/331 (33%), Gaps = 68/331 (20%) Query: 81 VPIEK-LQVNGITMADVKKLRESGL--HTAEAVAYAPRKDLLEIKGISEAKADKLLNEAA 137 V ++K + +N +T LR H P L+ ++ + ++ + ++ Sbjct: 60 VDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYE-MIGGLD 118 Query: 138 RLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHT 197 + + E+I L L LG G + L+G TGK+ L Sbjct: 119 KQI-----------KEIKEVIELPVKHPELFEALGIAQPKGVL--LYGPPGTGKTLLARA 165 Query: 198 LAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADH 257 +A C +I + + + Sbjct: 166 VAHHTD-----------CTFIR------------------VSGSELVQKFI-------GE 189 Query: 258 QLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFS-GRGELSARQMHLAKFMRALQRLADQ 316 R++ M E S+I +D + ++ + G G S Q + + + L Sbjct: 190 GARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEAT 249 Query: 317 FGVAVVV-TNQVV---------AQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGC 366 + V++ TN++ ++D + F P P + +I+ S ++ +G Sbjct: 250 KNIKVIMATNRIDILDSALLRPGRIDRKIEF-PPPNEEARLDILKIHSR-KMNLTRGINL 307 Query: 367 QRLCKVVDSPCLPEAECVFAIYEDGVGDPRE 397 +++ +++ P AE E G+ RE Sbjct: 308 RKIAELM--PGASGAEVKGVCTEAGMYALRE 336 >5U1D-A nrPDB Length = 748 Score = 31.2 bits (69), Expect = 0.75, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 43/135 (31%), Gaps = 7/135 (5%) Query: 175 VETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQ 234 + G +T L G +GKS + L Q +GK L E + ++ ++ Q Sbjct: 528 LRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPL-PQYEHRYLHRQVAAVGQ 586 Query: 235 RFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRG 294 + N+AY + + A + S I + Y T+ G Sbjct: 587 EPQVFGRSLQENIAYGLTQKPTME----EITAAAVKSGAHSFI--SGLPQGYDTEVDEAG 640 Query: 295 ELSARQMHLAKFMRA 309 + A + Sbjct: 641 SQLSGGQRQAVALAR 655 >5E7P-A nrPDB Length = 745 Score = 30.9 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 62/179 (34%), Gaps = 25/179 (13%) Query: 116 KDLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGV 175 L I+ +S + ++++ + L +G + + + L L ++ DT G+ Sbjct: 461 GALTVIRPLSRSASEEVSVGSVTLDDVGDMVETKRALTEAVLWPL----QHPDTFSRLGI 516 Query: 176 ETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQR 235 + L+G GK+ + LA + ++ + G + + Sbjct: 517 DPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGS-----------------ELMDKW 559 Query: 236 FGLDPDDALNNVAYARAYNADHQLRLLDAAAQMM--SESRFSLIVVDSVMALYRTDFSG 292 G +ARA ++ L LD + F V D V+A T+ G Sbjct: 560 VGSSEKAV--RELFARARDSAPSLVFLDEIDALAPRRGQNFDSGVTDKVVASLLTELDG 616 >5GJQ-J nrPDB Length = 406 Score = 30.9 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 53/331 (16%), Positives = 110/331 (33%), Gaps = 68/331 (20%) Query: 81 VPIEK-LQVNGITMADVKKLRESGL--HTAEAVAYAPRKDLLEIKGISEAKADKLLNEAA 137 V ++K + +N +T LR H P L+ ++ + ++ + ++ Sbjct: 97 VDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYE-MIGGLD 155 Query: 138 RLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHT 197 + + E+I L L LG G + L+G TGK+ L Sbjct: 156 KQI-----------KEIKEVIELPVKHPELFEALGIAQPKGVL--LYGPPGTGKTLLARA 202 Query: 198 LAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADH 257 +A C +I + + + Sbjct: 203 VAHHTD-----------CTFIR------------------VSGSELVQKFI-------GE 226 Query: 258 QLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFS-GRGELSARQMHLAKFMRALQRLADQ 316 R++ M E S+I +D + ++ + G G S Q + + + L Sbjct: 227 GARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEAT 286 Query: 317 FGVAVVV-TNQVV---------AQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGC 366 + V++ TN++ ++D + F P P + +I+ S ++ +G Sbjct: 287 KNIKVIMATNRIDILDSALLRPGRIDRKIEF-PPPNEEARLDILKIHSR-KMNLTRGINL 344 Query: 367 QRLCKVVDSPCLPEAECVFAIYEDGVGDPRE 397 +++ +++ P AE E G+ RE Sbjct: 345 RKIAELM--PGASGAEVKGVCTEAGMYALRE 373 >2QW5-A nrPDB Length = 335 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 44/120 (36%), Gaps = 19/120 (15%) Query: 84 EKLQVNGITMADVKKLRESGLHTAE-AVA-------------YAPRKDLLEIKGISEAKA 129 + L I +A +KKL+ G E +A Y + L+ +G+ K Sbjct: 25 DNLDYRRIVVAHIKKLQRFGYSGFEFPIAPGLPENYAQDLENYTNLRHYLDSEGLENVKI 84 Query: 130 DKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRT 189 + F ++++ +R E + ++ LGG + G I +G F T Sbjct: 85 STNVGATRT-----FDPSSNYPEQRQEALEYLKSRVDITAALGGEIMMGPIVIPYGVFPT 139 >5VHP-C nrPDB Length = 266 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 44/257 (17%), Positives = 85/257 (33%), Gaps = 53/257 (20%) Query: 152 MRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGG 211 E+I L L LG G + L+G TGK+ L +A Sbjct: 30 KEIKEVIELPVKHPELFEALGIAQPKGVL--LYGPPGTGKTLLARAVAHHTD-------- 79 Query: 212 EGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSE 271 C +I + + + R++ M E Sbjct: 80 ---CTFIR------------------VSGSELVQKFI-------GEGARMVRELFVMARE 111 Query: 272 SRFSLIVVDSVMALYRTDFS-GRGELSARQMHLAKFMRALQRLADQFGVAVVV-TNQVV- 328 S+I +D + ++ + G G S Q + + + L + V++ TN++ Sbjct: 112 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 171 Query: 329 --------AQVDGGMAFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPE 380 ++D + F P P + +I+ S ++ +G +++ +++ P Sbjct: 172 LDSALLRPGRIDRKIEF-PPPNEEARLDILKIHSR-KMNLTRGINLRKIAELM--PGASG 227 Query: 381 AECVFAIYEDGVGDPRE 397 AE E G+ RE Sbjct: 228 AEVKGVCTEAGMYALRE 244 >3JCO-J nrPDB Length = 405 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 36/145 (24%), Positives = 52/145 (35%), Gaps = 8/145 (5%) Query: 57 LQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRK 116 LQE GE+ D+ L P K V+ +VK L+ S + +Y K Sbjct: 65 LQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHK 124 Query: 117 DLLEIKG--ISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGG 174 L +S +K+ + +V G E+I L L LG Sbjct: 125 VLENKADPLVSLMMVEKVPDSTYDMVG-GLTKQI---KEIKEVIELPVKHPELFESLGIA 180 Query: 175 VETGSITELFGEFRTGKSQLCHTLA 199 G I L+G TGK+ L +A Sbjct: 181 QPKGVI--LYGPPGTGKTLLARAVA 203 >5BN5-A nrPDB Length = 570 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 162 TGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLA 199 TG++ LD + + G + G F +GK+ L +A Sbjct: 202 TGTRVLDIMFP--IAKGGSAAVPGPFGSGKTVLNQQIA 237 >1WNB-A nrPDB Length = 495 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 49/155 (31%), Gaps = 20/155 (12%) Query: 124 ISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITEL 183 I+ A KL A + P G V I G D L G + L Sbjct: 197 ITPLTALKLAELAKDIFPAGVVN-----------ILFGRGKTVGDPLT--GHPKVRMVSL 243 Query: 184 FGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFG---LDP 240 G TG+ + HT + + +++GG ++ D +V + FG Sbjct: 244 TGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDA----DIEAVVEGVRTFGYYNAGQ 299 Query: 241 DDALNNVAYARAYNADHQLRLLDAAAQMMSESRFS 275 D YA+ D + L AA + Sbjct: 300 DCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPD 334 >1JJ7-A nrPDB Length = 260 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 43/135 (31%), Gaps = 7/135 (5%) Query: 175 VETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQ 234 + G +T L G +GKS + L Q +GK L E + ++ ++ Q Sbjct: 40 LRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPL-PQYEHRYLHRQVAAVGQ 98 Query: 235 RFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRG 294 + N+AY + + A + S I + Y T+ G Sbjct: 99 EPQVFGRSLQENIAYGLTQKPTME----EITAAAVKSGAHSFI--SGLPQGYDTEVDEAG 152 Query: 295 ELSARQMHLAKFMRA 309 + A + Sbjct: 153 SQLSGGQRQAVALAR 167 >5TV4-A nrPDB Length = 605 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 3/94 (3%) Query: 175 VETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQ 234 + G L G +GKS + + I +G L T + R ++ ++Q Sbjct: 389 IPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLR-NQVALVSQ 447 Query: 235 RFGLDPDDALNNVAYARAYNADHQLRLLDAAAQM 268 L D NN+AYAR + ++ AA+M Sbjct: 448 NVHLFNDTVANNIAYAR--TEQYSREQIEEAARM 479 >4QIW-C nrPDB Length = 391 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 43/103 (41%), Gaps = 5/103 (4%) Query: 216 LYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFS 275 +Y+D E + + + +A+R L N+A + + +++ + + ++ Sbjct: 118 VYLDEEHRYDRDKALEVARRI---EGTTLENLAREETIDILNMEYVVEIDPERLEKAGLD 174 Query: 276 L-IVVDSVMALYR-TDFSGRGELSARQMHLAKFMRALQRLADQ 316 + VV + ++ +F G + + L+++A++ Sbjct: 175 MEKVVRKLTGSFKSAEFEAEGYTLVVRPKKVTKLSDLRKIAEK 217 >4AYX-A nrPDB Length = 595 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 13/20 (65%) Query: 175 VETGSITELFGEFRTGKSQL 194 + +GS+T L G +GKS + Sbjct: 367 IPSGSVTALVGPSGSGKSTV 386 >6IC4-I nrPDB Length = 233 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 15/40 (37%) Query: 175 VETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGK 214 + G IT + G TGK+ L + +GK Sbjct: 24 IRRGQITAIMGPSGTGKTTLLRLIGGQLVPDQGEVLLDGK 63 >1IW7-A nrPDB Length = 315 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 19/40 (47%) Query: 99 LRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAAR 138 L+E G+ + A+ KDL I GI E +++ + Sbjct: 269 LKEEGIESVRALLALNLKDLKNIPGIGERSLEEIKEALEK 308 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.129 0.317 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,536,124 Number of Sequences: 36641 Number of extensions: 523752 Number of successful extensions: 1830 Number of sequences better than 10.0: 70 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 1662 Number of HSP's gapped (non-prelim): 121 length of query: 400 length of database: 10,336,785 effective HSP length: 99 effective length of query: 301 effective length of database: 6,709,326 effective search space: 2019507126 effective search space used: 2019507126 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 60 (27.8 bits)