BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P25325 (297 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4JGT-A nrPDB 576 e-165 5WQK-A nrPDB 521 e-148 1BOH-A nrPDB 375 e-104 1URH-A nrPDB 204 3e-53 3UTN-X nrPDB 161 4e-40 1UAR-A nrPDB 111 4e-25 3AAX-A nrPDB 106 1e-23 3HZU-A nrPDB 85 4e-17 3P3A-A nrPDB 83 1e-16 1OKG-A nrPDB 82 4e-16 1H4M-X nrPDB 80 8e-16 2WLX-A nrPDB 72 4e-13 2EG4-A nrPDB 38 0.005 6BEV-A nrPDB 37 0.008 1NMO-A nrPDB 33 0.19 3D1P-A nrPDB 32 0.41 2HEI-A nrPDB 32 0.43 3DMS-A nrPDB 30 0.93 4G01-B nrPDB 30 1.6 1AI3-A nrPDB 29 2.0 3FSU-A nrPDB 28 4.6 2D4V-A nrPDB 28 5.5 1YT8-A nrPDB 28 6.9 5Z6P-A nrPDB 28 7.0 >4JGT-A nrPDB Length = 299 Score = 576 bits (1485), Expect = e-165, Method: Compositional matrix adjust. Identities = 279/279 (100%), Positives = 279/279 (100%) Query: 11 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS 70 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS Sbjct: 21 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS 80 Query: 71 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 130 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG Sbjct: 81 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 140 Query: 131 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR 190 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR Sbjct: 141 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR 200 Query: 191 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS 250 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS Sbjct: 201 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS 260 Query: 251 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI 289 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI Sbjct: 261 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI 299 >5WQK-A nrPDB Length = 293 Score = 521 bits (1342), Expect = e-148, Method: Compositional matrix adjust. Identities = 245/292 (83%), Positives = 268/292 (91%) Query: 5 QLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQ 64 QL RALVSAQWVAEAL+APR+ QPL+LLDASWYLPKLGRDARREFEERHIPGAAFFDID+ Sbjct: 1 QLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDR 60 Query: 65 CSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHA 124 SD TSPYDHMLP A HFA+YAG LGV AATHVVIYD SDQGLYSAPRVWWMFRAFGHH+ Sbjct: 61 SSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHS 120 Query: 125 VSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSR 184 VSLLDGG RHWL QNLP+SSGKS PAEF AQLDP+FIKT+EDI ENL++RRFQVVD+R Sbjct: 121 VSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDAR 180 Query: 185 ATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPL 244 A GRF+GT+PEPRDGIEPGHIPG+VNIPFT+FL+ EGLEKSPEEI+ LF+EKKVDLSKPL Sbjct: 181 AAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPL 240 Query: 245 VATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKT 296 VATCGSGVTA HV LGA+L GK DVP+YDGSWVEWYMRA+PE +ISEGRGKT Sbjct: 241 VATCGSGVTASHVVLGAFLSGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKT 292 >1BOH-A nrPDB Length = 296 Score = 375 bits (962), Expect = e-104, Method: Compositional matrix adjust. Identities = 172/290 (59%), Positives = 227/290 (78%), Gaps = 2/290 (0%) Query: 6 LCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQC 65 L RALVS +W+AE++RA + G L++LDASWY P R+AR+E+ ERH+PGA+FFDI++C Sbjct: 5 LYRALVSTKWLAESVRAGKVGPGLRVLDASWYSPGT-REARKEYLERHVPGASFFDIEEC 63 Query: 66 SDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAV 125 D+ SPY+ MLP FA+Y G LG+ THVV+YD D G + APRVWWMFR FGH V Sbjct: 64 RDKASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTV 123 Query: 126 SLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRA 185 S+L+GG R+WL++ P++S S+P PA F+A L+ + +KTYE + ENLES+RFQ+VDSRA Sbjct: 124 SVLNGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRA 183 Query: 186 TGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPL 244 GR+ GT+PEP G++ GHI G+VN+PF +FL+++G EKSPEE+R +F+ KKVDL+KPL Sbjct: 184 QGRYLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPL 243 Query: 245 VATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRG 294 +ATC GVTACH+AL AYLCGKPDV IYDGSW EW+ RA PE +S+G+G Sbjct: 244 IATCRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRAPPETWVSQGKG 293 >1URH-A nrPDB Length = 280 Score = 204 bits (519), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 111/275 (40%), Positives = 152/275 (55%), Gaps = 8/275 (2%) Query: 10 LVSAQWVAEALRAPRAGQPLQLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDQCSDR 68 V A W+AE + P +Q++DA P + R+ +E+ HIPGA FFDI+ SD Sbjct: 5 FVGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 60 Query: 69 TSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLL 128 TSP HMLP E FA LGV H+++YD + L+SAPR WWM R FG VS+L Sbjct: 61 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGN--LFSAPRAWWMLRTFGVEKVSIL 118 Query: 129 DGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGR 188 GGL W R +L L G + EF A +P + D+ Q++D+R R Sbjct: 119 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 178 Query: 189 FRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATC 248 F EPR G+ GHIPG +N+P+T+ L +EG K+ +E+ +F + V KP++ +C Sbjct: 179 FNAEVDEPRPGLRRGHIPGALNVPWTE-LVREGELKTTDELDAIFFGRGVSYDKPIIVSC 237 Query: 249 GSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRA 283 GSGVTA V L P+V +YDG+W EW RA Sbjct: 238 GSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 272 >3UTN-X nrPDB Length = 327 Score = 161 bits (407), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 104/282 (36%), Positives = 143/282 (50%), Gaps = 25/282 (8%) Query: 32 LDASWYLPKLGRDARREFEER-HIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLG 90 +DA+WYLP D + +F + IP + FFDID SD+ SPY HM P + F + LG Sbjct: 50 VDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLG 109 Query: 91 VGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKS--- 147 V +V+YD G +S+PR W GH V LL+ + PL S K Sbjct: 110 VQKDDILVVYDRV--GNFSSPRCAWTLGVMGHPKVYLLNN-FNQYREFKYPLDSSKVAAF 166 Query: 148 QPAPA---EFRAQLDPAFIKTYEDIKENLES----RRFQVVDSRATGRFRGTEPEPRDGI 200 P P E I YE++ + ++S ++F D+R+ GRF GTEPEPR I Sbjct: 167 SPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEPRSDI 226 Query: 201 EPGHIPGTVNIPFTDFLSQEGLEKSPE--EIRHLFQEK-------KVDLSKPLVATCGSG 251 GHIPGT +P+ L E + PE E H EK +D SKP + +CG+G Sbjct: 227 PSGHIPGTQPLPYGSLLDPE-TKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTG 285 Query: 252 VTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGR 293 V+ + L G P+V +YDGSW EW +++ PE I+E R Sbjct: 286 VSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPE-WIAENR 326 >1UAR-A nrPDB Length = 285 Score = 111 bits (278), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 84/281 (29%), Positives = 131/281 (46%), Gaps = 26/281 (9%) Query: 9 ALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDR 68 LVS WV E L P+ +++L+ + ++ HIPGA ID D Sbjct: 8 VLVSTDWVQEHLEDPK----VRVLEVD--------EDILLYDTGHIPGAQ--KIDWQRDF 53 Query: 69 TSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLL 128 P E FA+ RLG+ T VV+Y D+ + A +W F+ GH V L+ Sbjct: 54 WDPVVRDFISEEEFAKLMERLGISNDTTVVLY--GDKNNWWAAYAFWFFKYNGHKDVRLM 111 Query: 129 DGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTY-EDIKENL---ESRRFQVVDSR 184 +GG + W+ + PL++ P + I+ Y +D+ E++ + + +VD R Sbjct: 112 NGGRQKWVEEGRPLTTEVPSYPPGRYEVPYRDESIRAYRDDVLEHIIKVKEGKGALVDVR 171 Query: 185 ATGRFRGTEPE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVD 239 + +RG P++G + GHIPG NIP+ ++ +G KS EE+R L++ + Sbjct: 172 SPQEYRGELTHMPDYPQEGALRAGHIPGAKNIPWAKAVNPDGTFKSAEELRALYEPLGIT 231 Query: 240 LSKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEW 279 K +V C + H + YL G P V YDGSW EW Sbjct: 232 KDKDIVVYCRIAERSSHSWFVLKYLLGYPHVKNYDGSWTEW 272 >3AAX-A nrPDB Length = 277 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 78/280 (27%), Positives = 122/280 (43%), Gaps = 25/280 (8%) Query: 7 CRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCS 66 C LVSA W L AP+ ++ D ++ HI GA +D + Sbjct: 4 CDVLVSADWAESNLHAPKV-----------VFVEVDEDTS-AYDRDHIAGA--IKLDWRT 49 Query: 67 DRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVS 126 D P A+ F++ G+ V++Y ++ + A +W F+ +GH V Sbjct: 50 DLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNNN--WFAAYAYWYFKLYGHEKVK 107 Query: 127 LLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQ-VVDSRA 185 LLDGG + W PLSS + A I+ + D E L + + ++D R+ Sbjct: 108 LLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRD--EVLAAINVKNLIDVRS 165 Query: 186 TGRFRGTEPEP-----RDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL 240 F G P PGHIPG +N+P++ +++G KS EE+ L+ + +D Sbjct: 166 PDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDN 225 Query: 241 SKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEW 279 SK +A C G + H + L G +V YDGSW E+ Sbjct: 226 SKETIAYCRIGERSSHTWFVLRELLGHQNVKNYDGSWTEY 265 >3HZU-A nrPDB Length = 318 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 83/283 (29%), Positives = 123/283 (43%), Gaps = 38/283 (13%) Query: 10 LVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRT 69 LV+A W++ + AP G + D L +G HIPGA ID +D Sbjct: 41 LVTADWLSAHMGAP--GLAIVESDEDVLLYDVG----------HIPGAV--KIDWHTDLN 86 Query: 70 SPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLD 129 P E FAE R G+ VVIY D+ + A W+F FGH V LL+ Sbjct: 87 DPRVRDYINGEQFAELMDRKGIARDDTVVIY--GDKSNWWAAYALWVFTLFGHADVRLLN 144 Query: 130 GGLRHWLRQ------NLPLSSGKSQPAPAEFRAQLDPAFIKTY-EDIKENLESRRFQVVD 182 GG WL + ++P + P Q + A I+ + +D+ L ++ ++D Sbjct: 145 GGRDLWLAERRETTLDVPTKTCTGYPV-----VQRNDAPIRAFRDDVLAILGAQ--PLID 197 Query: 183 SRATGRFRGTEPE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKK 237 R+ + G P +G + GHIP V+IP+ + G +S EE+ L+ Sbjct: 198 VRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYD--F 255 Query: 238 VDLSKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEW 279 ++ V C G + H + +L GK DV YDGSW EW Sbjct: 256 INPDDQTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEW 298 >3P3A-A nrPDB Length = 320 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 79/272 (29%), Positives = 119/272 (43%), Gaps = 29/272 (10%) Query: 27 QPLQLLDASWYLPKLGR---------DARREFEERHIPGAAFFDIDQCSDRTSPYDHMLP 77 P +L+ A W LGR + ++ HIPGA ID +D P Sbjct: 38 HPERLVTADWLASNLGRPGLVIVESDEDVLLYDTGHIPGAV--KIDWHTDLNDPAVRDYI 95 Query: 78 GAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLR 137 E FA R GV VVIY D+ + A W+F FGH V LLDGG W+ Sbjct: 96 NGEQFAALMDRKGVTRDDTVVIY--GDKSNWWAAYAMWVFHLFGHPDVRLLDGGRDLWVS 153 Query: 138 Q----NLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTE 193 L + + ++ P R + A I+ ++D + + ++D R+ + G Sbjct: 154 TGRDTTLEVPTRQTSGYPVVER---NDAPIRAFKDDVLRVLGKE-PLIDVRSPQEYTGER 209 Query: 194 PE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATC 248 P +G + GHIP V++P++ +G ++ E+ ++ K D KP+V C Sbjct: 210 THMPDYPEEGALRGGHIPTAVSVPWSKAAYDDGRFRARAELEEIYGFVKPD-DKPIVY-C 267 Query: 249 GSGVTACHV-ALGAYLCGKPDVPIYDGSWVEW 279 G + H + YL G P+V YDGSW EW Sbjct: 268 RIGERSSHTWFVLTYLLGHPNVRNYDGSWTEW 299 >1OKG-A nrPDB Length = 373 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 125/273 (45%), Gaps = 28/273 (10%) Query: 30 QLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDR---TSPYDHMLPGAEHFAEYA 86 +++D + L K+ ++ + H+ A D+D + TS H LP F ++ Sbjct: 29 RIVDCRYSL-KIKDHGSIQYAKEHVKSAIRADVDTNLSKLVPTSTARHPLPPCAEFIDWC 87 Query: 87 GRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGK 146 G+ V+ YD + G R+WWM + G A +++GG + L + SG+ Sbjct: 88 MANGMAGELPVLCYD-DECGAMGGCRLWWMLNSLGADAY-VINGGFQACKAAGLEMESGE 145 Query: 147 --SQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGT-EPEPRDGIEPG 203 S P PA AF Y + + + + + D+R+ RF T P D + PG Sbjct: 146 PSSLPRPAT-HWPFKTAFQHHY--LVDEIPPQAI-ITDARSADRFASTVRPYAADKM-PG 200 Query: 204 HIPGTVNIPFTDFLSQEG---LEKSPEEIRHLFQE------KKVDLSKPLVATCGSGVTA 254 HI G N+P+T L G + +S EEIRH DLS V +CGSGVTA Sbjct: 201 HIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQGAGDAADLSS-FVFSCGSGVTA 259 Query: 255 C-HVALGAYL-CGKPDVPIYDGSWVEWYMRARP 285 C ++AL +L G P +Y GSW E+ RP Sbjct: 260 CINIALVHHLGLGHPY--LYCGSWSEYSGLFRP 290 >1H4M-X nrPDB Length = 271 Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 94/233 (40%), Gaps = 9/233 (3%) Query: 49 FEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLY 108 + E HIPGA F D + P + P E G LG V+YD D+G Sbjct: 36 YAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGELGHRPEAVYVVYD--DEGGG 93 Query: 109 SAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPA--PAEFRAQLDPAFIKTY 166 A R W+ G L+GGL WL ++ PLS PA P +P + Y Sbjct: 94 WAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSRELPAPAGGPVALSLHDEPTASRDY 153 Query: 167 EDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSP 226 + L + + D+R+ +RG + G GHIPG VN +T + + Sbjct: 154 --LLGRLGAADLAIWDARSPQEYRGEKVLAAKG---GHIPGAVNFEWTAAMDPSRALRIR 208 Query: 227 EEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEW 279 +I +E + K +V C + + L A G P V Y GSW EW Sbjct: 209 TDIAGRLEELGITPDKEIVTHCQTHHRSGLTYLIAKALGYPRVKGYAGSWGEW 261 >2WLX-A nrPDB Length = 423 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 74/300 (24%), Positives = 129/300 (43%), Gaps = 34/300 (11%) Query: 10 LVSAQWV-----AEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQ 64 LV QW+ + + A AG ++++A+W PKL + HIPGA + D ++ Sbjct: 125 LVYPQWLHDLQQGKEVTAKPAGD-WKVIEAAWGAPKL-------YLISHIPGADYIDTNE 176 Query: 65 CSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHA 124 + P + + E + G+ T V++Y + +Y+A RV + G Sbjct: 177 V--ESEPLWNKV-SDEQLKAMLAKHGIRHDTTVILYG---RDVYAAARVAQIMLYAGVKD 230 Query: 125 VSLLDGGLRHWLRQNLPLSSGKSQPAPAE----FRAQLDPAFIKTYEDIKENLESRRFQV 180 V LLDGG + W LP+ G AE + P + E + L + + Sbjct: 231 VRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASL 290 Query: 181 VDSRATGRFRGTEP-----EPRD---GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHL 232 V R+ F GT +P+ G GH G+ + DF + +G +S ++I + Sbjct: 291 VSIRSWPEFIGTTSGYSYIKPKGEIAGARWGHA-GSDSTHMEDFHNPDGTMRSADDITAM 349 Query: 233 FQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEG 292 ++ + + + CG+G A + A G +V +YDG W EW + P++ ++ G Sbjct: 350 WKAWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEW--SSDPKNPVATG 407 >2EG4-A nrPDB Length = 230 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 20/179 (11%) Query: 46 RREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQ 105 R +E H+PGA D+ R + E LG+ + VV+YD + Sbjct: 15 RPAYEAGHLPGARHLDLSAPKLRLREEAELKALEGGLTELFQTLGL--RSPVVLYD---E 69 Query: 106 GLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAP--AEFRAQLDPAFI 163 GL S F G V L W P ++ K +P P E A+L ++ Sbjct: 70 GLTSRLCRTAFFLGLGGLEVQL-------WTEGWEPYATEKEEPKPERTEVVAKLRRDWL 122 Query: 164 KTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGL 222 T ++ +R ++D R+ F+G + P G IPG+ N P FLS EGL Sbjct: 123 LTADEA-----ARHPLLLDVRSPEEFQG-KVHPPCCPRGGRIPGSKNAPLELFLSPEGL 175 >6BEV-A nrPDB Length = 135 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 185 ATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLS-KP 243 A+GR R + R+ G IPG +NIP ++ + L+ P + L+ +K L + Sbjct: 37 ASGRARLFDVRSREEAAAGTIPGALNIPVSEL--ESALQMEPAAFQALYSAEKPKLEDEH 94 Query: 244 LVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEW 279 LV C G A G Y G++ EW Sbjct: 95 LVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREW 130 >1NMO-A nrPDB Length = 247 Score = 32.7 bits (73), Expect = 0.19, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 78 GAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLR---H 134 G + F + A R GV A + + S+Q ++SA F A GHHA GG+R Sbjct: 174 GGQSFIDSAARFGVDA---FITGEVSEQTIHSAREQGLHFYAAGHHATE--RGGIRALSE 228 Query: 135 WLRQNLPL 142 WL +N L Sbjct: 229 WLNENTDL 236 >3D1P-A nrPDB Length = 139 Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 2/76 (2%) Query: 204 HIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYL 263 HIP ++N+P+ L+ P E K D +K L+ C SG A Sbjct: 56 HIPASINVPYRSHPDAFALD--PLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASS 113 Query: 264 CGKPDVPIYDGSWVEW 279 G + +Y GS +W Sbjct: 114 HGYSNTSLYPGSMNDW 129 >2HEI-A nrPDB Length = 179 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Query: 48 EFEERHIPGAAFFDIDQCSDRTSPYDHM--LPGAEHFAEYAGRLGVGAATHVVIYDASDQ 105 E++E I GAAF C D T+ + G E + A GA +V+YD ++Q Sbjct: 35 EYQESTI-GAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQ 93 Query: 106 GLYSAPRVW 114 ++ + W Sbjct: 94 ETFARAKTW 102 >3DMS-A nrPDB Length = 427 Score = 30.4 bits (67), Expect = 0.93, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 4/46 (8%) Query: 226 PEEIRHLFQEKKVDLSKPLVATCGSGVTACHVA----LGAYLCGKP 267 PEE + +E V + PL G G+ + +VA L Y+C +P Sbjct: 95 PEETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRP 140 >4G01-B nrPDB Length = 181 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 7/76 (9%) Query: 43 RDARREFEERHIPGAAFFD----IDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVV 98 +D EF+E I GAAFF ++ + + +D G E + A GAA ++ Sbjct: 34 KDQFVEFQESTI-GAAFFSQTLAVNDATVKFEIWDT--AGQERYHSLAPMYYRGAAAAII 90 Query: 99 IYDASDQGLYSAPRVW 114 ++D ++Q + + W Sbjct: 91 VFDVTNQASFERAKKW 106 >1AI3-A nrPDB Length = 416 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 226 PEEIRHLFQEKKVDLSKPLVATCGSGVTACHVA----LGAYLCGKPDVPIYDGS 275 P E L +E +V + PL G G+ + +VA L Y+C +P V Y G+ Sbjct: 85 PAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRP-VRYYQGT 137 >3FSU-A nrPDB Length = 304 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 15/61 (24%) Query: 88 RLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHW--LRQNLPLSSG 145 R G+ AA H+ DA+ L + R +W + G+RH LR +LP SG Sbjct: 80 RTGLEAAPHLTCIDATPDELRTIARDYW-------------NNGIRHIVALRGDLPPGSG 126 Query: 146 K 146 K Sbjct: 127 K 127 >2D4V-A nrPDB Length = 429 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Query: 226 PEEIRHLFQEKKVDLSKPLVATCGSGVTACHVA----LGAYLCGKPDVPIYDGS 275 P+E +E KV + PL G G+ + +VA L Y+C +P V ++G+ Sbjct: 85 PDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDLDLYVCLRP-VRYFEGT 137 >1YT8-A nrPDB Length = 539 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 37/137 (27%), Positives = 49/137 (35%), Gaps = 26/137 (18%) Query: 15 WVAEALRAPRAGQPLQLLDASWY----LPKLGRDARREFEERHIPGAAFFDIDQCSDRTS 70 W A R PRA A W L A + +RHIPGAA+ Q Sbjct: 366 WSAPLPRQPRADTIDPTTLADWLGEPGTRVLDFTASANYAKRHIPGAAWVLRSQ------ 419 Query: 71 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 130 + RLG A +V+ +S ++ V +A V LLDG Sbjct: 420 -----------LKQALERLGT-AERYVLTCGSSLLARFAVAEV----QALSGKPVFLLDG 463 Query: 131 GLRHWLRQNLPLSSGKS 147 G W+ LP G+S Sbjct: 464 GTSAWVAAGLPTEDGES 480 >5Z6P-A nrPDB Length = 765 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 21/106 (19%) Query: 92 GAATHV--VIYDASDQGLYSAPRVWWMFRA-------FGHHAVSLLDGGLRHWLRQNLPL 142 AA HV V Y+ +GL+ P W F A G LD G H Sbjct: 632 AAAKHVDVVSYNYYKEGLHPEP---WSFLADIDMPSIIGEFHFGALDSGFFH-------- 680 Query: 143 SSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGR 188 +G + R Q+ +++T D + + FQ +DS TGR Sbjct: 681 -AGLVTACSQQERGQMFERYMQTVVDNPYFVGAHYFQYIDSPITGR 725 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5WQK-A nrPDB 420 e-118 4JGT-A nrPDB 404 e-113 1BOH-A nrPDB 395 e-110 1URH-A nrPDB 321 2e-88 1UAR-A nrPDB 311 2e-85 3AAX-A nrPDB 292 1e-79 3UTN-X nrPDB 291 3e-79 3HZU-A nrPDB 274 3e-74 2WLX-A nrPDB 272 2e-73 3P3A-A nrPDB 271 2e-73 1H4M-X nrPDB 256 8e-69 1OKG-A nrPDB 236 6e-63 Sequences not found previously or not previously below threshold: 2EG4-A nrPDB 99 2e-21 3D1P-A nrPDB 64 1e-10 6BEV-A nrPDB 63 1e-10 1YT8-A nrPDB 62 3e-10 1TQ1-A nrPDB 42 4e-04 2JTQ-A nrPDB 37 0.007 1C25-A nrPDB 36 0.020 3NTA-A nrPDB 34 0.078 1QB0-A nrPDB 34 0.079 1GN0-A nrPDB 32 0.30 4WH9-A nrPDB 32 0.34 6HIZ-Ci nrPDB 32 0.34 5E7P-A nrPDB 32 0.35 4AEE-A nrPDB 32 0.43 3EKG-A nrPDB 30 1.1 3CSQ-A nrPDB 30 1.3 2ZIV-A nrPDB 30 1.4 1C4O-A nrPDB 30 1.6 5GTM-A nrPDB 29 1.8 6J5C-A nrPDB 29 1.9 5NPF-A nrPDB 29 3.1 1CX1-A nrPDB 27 9.6 >5WQK-A nrPDB Length = 293 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 245/293 (83%), Positives = 268/293 (91%) Query: 5 QLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQ 64 QL RALVSAQWVAEAL+APR+ QPL+LLDASWYLPKLGRDARREFEERHIPGAAFFDID+ Sbjct: 1 QLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDR 60 Query: 65 CSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHA 124 SD TSPYDHMLP A HFA+YAG LGV AATHVVIYD SDQGLYSAPRVWWMFRAFGHH+ Sbjct: 61 SSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHS 120 Query: 125 VSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSR 184 VSLLDGG RHWL QNLP+SSGKS PAEF AQLDP+FIKT+EDI ENL++RRFQVVD+R Sbjct: 121 VSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDAR 180 Query: 185 ATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPL 244 A GRF+GT+PEPRDGIEPGHIPG+VNIPFT+FL+ EGLEKSPEEI+ LF+EKKVDLSKPL Sbjct: 181 AAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPL 240 Query: 245 VATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH 297 VATCGSGVTA HV LGA+L GK DVP+YDGSWVEWYMRA+PE +ISEGRGKT Sbjct: 241 VATCGSGVTASHVVLGAFLSGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ 293 >4JGT-A nrPDB Length = 299 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 279/279 (100%), Positives = 279/279 (100%) Query: 11 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS 70 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS Sbjct: 21 VSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTS 80 Query: 71 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 130 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG Sbjct: 81 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 140 Query: 131 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR 190 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR Sbjct: 141 GLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFR 200 Query: 191 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS 250 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS Sbjct: 201 GTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGS 260 Query: 251 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI 289 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI Sbjct: 261 GVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI 299 >1BOH-A nrPDB Length = 296 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 172/290 (59%), Positives = 227/290 (78%), Gaps = 2/290 (0%) Query: 6 LCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQC 65 L RALVS +W+AE++RA + G L++LDASWY P R+AR+E+ ERH+PGA+FFDI++C Sbjct: 5 LYRALVSTKWLAESVRAGKVGPGLRVLDASWYSPGT-REARKEYLERHVPGASFFDIEEC 63 Query: 66 SDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAV 125 D+ SPY+ MLP FA+Y G LG+ THVV+YD D G + APRVWWMFR FGH V Sbjct: 64 RDKASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTV 123 Query: 126 SLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRA 185 S+L+GG R+WL++ P++S S+P PA F+A L+ + +KTYE + ENLES+RFQ+VDSRA Sbjct: 124 SVLNGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRA 183 Query: 186 TGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPL 244 GR+ GT+PEP G++ GHI G+VN+PF +FL+++G EKSPEE+R +F+ KKVDL+KPL Sbjct: 184 QGRYLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPL 243 Query: 245 VATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRG 294 +ATC GVTACH+AL AYLCGKPDV IYDGSW EW+ RA PE +S+G+G Sbjct: 244 IATCRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRAPPETWVSQGKG 293 >1URH-A nrPDB Length = 280 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 112/282 (39%), Positives = 155/282 (54%), Gaps = 9/282 (3%) Query: 10 LVSAQWVAEALRAPRAGQPLQLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDQCSDR 68 V A W+AE + P +Q++DA P + R+ +E+ HIPGA FFDI+ SD Sbjct: 5 FVGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 60 Query: 69 TSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLL 128 TSP HMLP E FA LGV H+++YD + L+SAPR WWM R FG VS+L Sbjct: 61 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGN--LFSAPRAWWMLRTFGVEKVSIL 118 Query: 129 DGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGR 188 GGL W R +L L G + EF A +P + D+ Q++D+R R Sbjct: 119 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 178 Query: 189 FRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATC 248 F EPR G+ GHIPG +N+P+T+ L +EG K+ +E+ +F + V KP++ +C Sbjct: 179 FNAEVDEPRPGLRRGHIPGALNVPWTE-LVREGELKTTDELDAIFFGRGVSYDKPIIVSC 237 Query: 249 GSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRAR-PEDVI 289 GSGVTA V L P+V +YDG+W EW RA P + + Sbjct: 238 GSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPV 279 >1UAR-A nrPDB Length = 285 Score = 311 bits (797), Expect = 2e-85, Method: Composition-based stats. Identities = 85/296 (28%), Positives = 130/296 (43%), Gaps = 28/296 (9%) Query: 8 RALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSD 67 LVS WV E L P+ ++L+ + ++ HIPGA ID D Sbjct: 7 EVLVSTDWVQEHLEDPKV----RVLEVD--------EDILLYDTGHIPGAQ--KIDWQRD 52 Query: 68 RTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSL 127 P E FA+ RLG+ T VV+Y D+ + A +W F+ GH V L Sbjct: 53 FWDPVVRDFISEEEFAKLMERLGISNDTTVVLY--GDKNNWWAAYAFWFFKYNGHKDVRL 110 Query: 128 LDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKEN----LESRRFQVVDS 183 ++GG + W+ + PL++ P + I+ Y D ++ + +VD Sbjct: 111 MNGGRQKWVEEGRPLTTEVPSYPPGRYEVPYRDESIRAYRDDVLEHIIKVKEGKGALVDV 170 Query: 184 RATGRFRGTEPE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKV 238 R+ +RG P++G + GHIPG NIP+ ++ +G KS EE+R L++ + Sbjct: 171 RSPQEYRGELTHMPDYPQEGALRAGHIPGAKNIPWAKAVNPDGTFKSAEELRALYEPLGI 230 Query: 239 DLSKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGR 293 K +V C + H + YL G P V YDGSW EW I++G Sbjct: 231 TKDKDIVVYCRIAERSSHSWFVLKYLLGYPHVKNYDGSWTEWGNLVG--VPIAKGE 284 >3AAX-A nrPDB Length = 277 Score = 292 bits (747), Expect = 1e-79, Method: Composition-based stats. Identities = 78/285 (27%), Positives = 121/285 (42%), Gaps = 25/285 (8%) Query: 7 CRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCS 66 C LVSA W L AP+ ++ D ++ HI GA +D + Sbjct: 4 CDVLVSADWAESNLHAPKV-----------VFVEVDEDTS-AYDRDHIAGAI--KLDWRT 49 Query: 67 DRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVS 126 D P A+ F++ G+ V++Y ++ + A +W F+ +GH V Sbjct: 50 DLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNN--NWFAAYAYWYFKLYGHEKVK 107 Query: 127 LLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRF-QVVDSRA 185 LLDGG + W PLSS + A I+ + D E L + ++D R+ Sbjct: 108 LLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRD--EVLAAINVKNLIDVRS 165 Query: 186 TGRFRGTEPEP-----RDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL 240 F G P PGHIPG +N+P++ +++G KS EE+ L+ + +D Sbjct: 166 PDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDN 225 Query: 241 SKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEWYMRAR 284 SK +A C G + H + L G +V YDGSW E+ Sbjct: 226 SKETIAYCRIGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVG 270 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 34/97 (35%), Gaps = 3/97 (3%) Query: 192 TEPEPRDGIEPGHIPGTVNIPF-TDFLSQ-EGLEKSPEEIRHLFQEKKVDLSKPLVATCG 249 E + HI G + + + TD + ++ L E+ + ++ G Sbjct: 26 EVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGG 85 Query: 250 SG-VTACHVALGAYLCGKPDVPIYDGSWVEWYMRARP 285 + A + L G V + DG +W + RP Sbjct: 86 NNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRP 122 >3UTN-X nrPDB Length = 327 Score = 291 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 111/313 (35%), Positives = 155/313 (49%), Gaps = 27/313 (8%) Query: 1 MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEER-HIPGAAF 59 MAS L L+S + + L A + +DA+WYLP D + +F + IP + F Sbjct: 21 MASMPLFD-LISPKAFVK-LVASEKVHRIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIF 78 Query: 60 FDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRA 119 FDID SD+ SPY HM P + F + LGV +V+YD G +S+PR W Sbjct: 79 FDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDRV--GNFSSPRCAWTLGV 136 Query: 120 FGHHAVSLLDGGLRHWLRQNLPLSSGKS---QPAPA---EFRAQLDPAFIKTYEDIKENL 173 GH V LL+ + PL S K P P E I YE++ + + Sbjct: 137 MGHPKVYLLNN-FNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLV 195 Query: 174 E----SRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPE-- 227 + +++F D+R+ GRF GTEPEPR I GHIPGT +P+ L E + PE Sbjct: 196 KSGELAKKFNAFDARSLGRFEGTEPEPRSDIPSGHIPGTQPLPYGSLLDPE-TKTYPEAG 254 Query: 228 EIRHLFQEKKV-------DLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWY 280 E H EK + D SKP + +CG+GV+ + L G P+V +YDGSW EW Sbjct: 255 EAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWV 314 Query: 281 MRARPEDVISEGR 293 +++ PE I+E R Sbjct: 315 LKSGPE-WIAENR 326 >3HZU-A nrPDB Length = 318 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 79/283 (27%), Positives = 123/283 (43%), Gaps = 28/283 (9%) Query: 10 LVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRT 69 LV+A W++ + AP L ++++ + ++ HIPGA ID +D Sbjct: 41 LVTADWLSAHMGAP----GLAIVESD--------EDVLLYDVGHIPGAV--KIDWHTDLN 86 Query: 70 SPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLD 129 P E FAE R G+ VVIY D+ + A W+F FGH V LL+ Sbjct: 87 DPRVRDYINGEQFAELMDRKGIARDDTVVIY--GDKSNWWAAYALWVFTLFGHADVRLLN 144 Query: 130 GGLRHWLRQNLPLSSGKSQPAPAEFR-AQLDPAFIKTY-EDIKENLESRRFQVVDSRATG 187 GG WL + + + Q + A I+ + +D+ L ++ ++D R+ Sbjct: 145 GGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAFRDDVLAILGAQ--PLIDVRSPE 202 Query: 188 RFRGTEPE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSK 242 + G P +G + GHIP V+IP+ + G +S EE+ L+ ++ Sbjct: 203 EYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLY--DFINPDD 260 Query: 243 PLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEWYMRAR 284 V C G + H + +L GK DV YDGSW EW R Sbjct: 261 QTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVR 303 >2WLX-A nrPDB Length = 423 Score = 272 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 74/304 (24%), Positives = 128/304 (42%), Gaps = 34/304 (11%) Query: 7 CRALVSAQWV-----AEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFD 61 LV QW+ + + A AG ++++A+W PKL + HIPGA + D Sbjct: 122 FEQLVYPQWLHDLQQGKEVTAKPAGD-WKVIEAAWGAPKL-------YLISHIPGADYID 173 Query: 62 IDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFG 121 ++ + P + + E + G+ T V++Y +Y+A RV + G Sbjct: 174 TNEV--ESEPLWNKV-SDEQLKAMLAKHGIRHDTTVILYGRD---VYAAARVAQIMLYAG 227 Query: 122 HHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAE----FRAQLDPAFIKTYEDIKENLESRR 177 V LLDGG + W LP+ G AE + P + E + L + Sbjct: 228 VKDVRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQARGLLHRQD 287 Query: 178 FQVVDSRATGRFRGTEP-----EPRD---GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEI 229 +V R+ F GT +P+ G GH G+ + DF + +G +S ++I Sbjct: 288 ASLVSIRSWPEFIGTTSGYSYIKPKGEIAGARWGHA-GSDSTHMEDFHNPDGTMRSADDI 346 Query: 230 RHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVI 289 +++ + + + CG+G A + A G +V +YDG W EW + P++ + Sbjct: 347 TAMWKAWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEW--SSDPKNPV 404 Query: 290 SEGR 293 + G Sbjct: 405 ATGE 408 >3P3A-A nrPDB Length = 320 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 81/285 (28%), Positives = 125/285 (43%), Gaps = 32/285 (11%) Query: 10 LVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRT 69 LV+A W+A L P L ++++ + ++ HIPGA ID +D Sbjct: 42 LVTADWLASNLGRP----GLVIVESD--------EDVLLYDTGHIPGAV--KIDWHTDLN 87 Query: 70 SPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLD 129 P E FA R GV VVIY D+ + A W+F FGH V LLD Sbjct: 88 DPAVRDYINGEQFAALMDRKGVTRDDTVVIY--GDKSNWWAAYAMWVFHLFGHPDVRLLD 145 Query: 130 GGLRHWLRQN----LPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRA 185 GG W+ L + + ++ P R + A I+ ++D + + ++D R+ Sbjct: 146 GGRDLWVSTGRDTTLEVPTRQTSGYPVVER---NDAPIRAFKDDVLRVLGKE-PLIDVRS 201 Query: 186 TGRFRGTEPE----PRDG-IEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL 240 + G P +G + GHIP V++P++ +G ++ E+ ++ K D Sbjct: 202 PQEYTGERTHMPDYPEEGALRGGHIPTAVSVPWSKAAYDDGRFRARAELEEIYGFVKPD- 260 Query: 241 SKPLVATCGSGVTACHV-ALGAYLCGKPDVPIYDGSWVEWYMRAR 284 KP+V C G + H + YL G P+V YDGSW EW R Sbjct: 261 DKPIV-YCRIGERSSHTWFVLTYLLGHPNVRNYDGSWTEWGNAVR 304 >1H4M-X nrPDB Length = 271 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 72/263 (27%), Positives = 103/263 (39%), Gaps = 14/263 (5%) Query: 32 LDASWYLPKL---GRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGR 88 L A P+L + + E HIPGA F D + P + P E G Sbjct: 16 LQARLSAPELILVDLTSAARYAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGE 75 Query: 89 LGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQ 148 LG V+YD D+G A R W+ G L+GGL WL ++ PLS Sbjct: 76 LGHRPEAVYVVYD--DEGGGWAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSRELPA 133 Query: 149 PA--PAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIP 206 PA P +P + Y + L + + D+R+ +RG + G GHIP Sbjct: 134 PAGGPVALSLHDEPTASRDY--LLGRLGAADLAIWDARSPQEYRGEKVLAAKG---GHIP 188 Query: 207 GTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGK 266 G VN +T + + +I +E + K +V C + + L A G Sbjct: 189 GAVNFEWTAAMDPSRALRIRTDIAGRLEELGITPDKEIVTHCQTHHRSGLTYLIAKALGY 248 Query: 267 PDVPIYDGSWVEWYMRARPEDVI 289 P V Y GSW EW P+ + Sbjct: 249 PRVKGYAGSWGEWG--NHPDTPV 269 >1OKG-A nrPDB Length = 373 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 85/295 (28%), Positives = 130/295 (44%), Gaps = 34/295 (11%) Query: 8 RALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSD 67 + + VA+ L +++D + L K+ ++ + H+ A D+D Sbjct: 13 KVFLDPSEVADHL------AEYRIVDCRYSL-KIKDHGSIQYAKEHVKSAIRADVDTNLS 65 Query: 68 R---TSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHA 124 + TS H LP F ++ G+ V+ YD + G R+WWM + G A Sbjct: 66 KLVPTSTARHPLPPCAEFIDWCMANGMAGELPVLCYD-DECGAMGGCRLWWMLNSLGADA 124 Query: 125 VSLLDGGLRHWLRQNLPLSSGKSQ--PAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVD 182 +++GG + L + SG+ P PA AF Y + + + + + D Sbjct: 125 Y-VINGGFQACKAAGLEMESGEPSSLPRPAT-HWPFKTAFQHHY--LVDEIPPQAI-ITD 179 Query: 183 SRATGRFRGT-EPEPRDGIEPGHIPGTVNIPFTDFLSQEG---LEKSPEEIRHLFQE--- 235 +R+ RF T P D + PGHI G N+P+T L G + +S EEIRH Sbjct: 180 ARSADRFASTVRPYAADKM-PGHIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQ 238 Query: 236 ---KKVDLSKPLVATCGSGVTAC-HVALGAYL-CGKPDVPIYDGSWVEWYMRARP 285 DLS V +CGSGVTAC ++AL +L G P +Y GSW E+ RP Sbjct: 239 GAGDAADLSS-FVFSCGSGVTACINIALVHHLGLGHPY--LYCGSWSEYSGLFRP 290 >2EG4-A nrPDB Length = 230 Score = 98.7 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 82/248 (33%), Gaps = 27/248 (10%) Query: 41 LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIY 100 + R +E H+PGA D+ R + E LG+ + VV+Y Sbjct: 10 VDTRPRPAYEAGHLPGARHLDLSAPKLRLREEAELKALEGGLTELFQTLGLR--SPVVLY 67 Query: 101 DASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP 160 D R + G V L G + + +P E A+L Sbjct: 68 DEGLTSRL--CRTAFFLGLGGLE-VQLWTEGW-----EPYATEKEEPKPERTEVVAKLRR 119 Query: 161 AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQE 220 ++ T ++ +R ++D R+ F+G P G IPG+ N P FLS E Sbjct: 120 DWLLTADEA-----ARHPLLLDVRSPEEFQGK-VHPPCCPRGGRIPGSKNAPLELFLSPE 173 Query: 221 GLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWY 280 G L + + + + C SG + G Y GS EW Sbjct: 174 G----------LLERLGLQPGQEVGVYCHSGARSAVAFFVLRSLGV-RARNYLGSMHEWL 222 Query: 281 MRARPEDV 288 P + Sbjct: 223 QEGLPTEP 230 >3D1P-A nrPDB Length = 139 Score = 63.7 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 43/124 (34%), Gaps = 15/124 (12%) Query: 165 TYEDIKENLESRRFQ--VVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGL 222 ++ED+K + +VD R + HIP ++N+P+ + Sbjct: 26 SFEDMKRIVGKHDPNVVLVDVREPSEYSIV-----------HIPASINVPYRSH--PDAF 72 Query: 223 EKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMR 282 P E K D +K L+ C SG A G + +Y GS +W Sbjct: 73 ALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSH 132 Query: 283 ARPE 286 + Sbjct: 133 GGDK 136 >6BEV-A nrPDB Length = 135 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 14/123 (11%) Query: 161 AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQE 220 A + +++ L S R ++ D R+ R+ G IPG +NIP ++ + Sbjct: 24 APTVSLPELRSLLASGRARLFDVRS-----------REEAAAGTIPGALNIPVSEL--ES 70 Query: 221 GLEKSPEEIRHLFQEKKVDLSKP-LVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEW 279 L+ P + L+ +K L LV C G A G Y G++ EW Sbjct: 71 ALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREW 130 Query: 280 YMR 282 + Sbjct: 131 LEK 133 >1YT8-A nrPDB Length = 539 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 55/180 (30%), Gaps = 30/180 (16%) Query: 92 GAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSG--KSQP 149 T + +YD + AP G+ V+LLDGGL W L Sbjct: 61 RRDTPITVYDDGE---GLAPVAAQRLHDLGYSDVALLDGGLSGWRNAGGELFRDVNVPSK 117 Query: 150 APAEFRAQLDPAFIKTYEDIKENLESRRFQVV-DSRATGRFRGTEPEPRDGIEPGHIPGT 208 A E E+++ L++R V+ D+R ++ IPG Sbjct: 118 AFGELVEAERHTPSLAAEEVQALLDARAEAVILDARRFDEYQTMS-----------IPGG 166 Query: 209 VNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPD 268 +++P E+ E D ++ C + G P+ Sbjct: 167 ISVP-------------GAELVLRVAELAPDPRTRVIVNCAGRTRSIIGTQSLLNAGIPN 213 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 29/152 (19%) Query: 15 WVAEALRAPRAGQPLQLLDASWYLPK----LGRDARREFEERHIPGAAFFDIDQCSDRTS 70 W A R PRA A W L A + +RHIPGAA+ Sbjct: 366 WSAPLPRQPRADTIDPTTLADWLGEPGTRVLDFTASANYAKRHIPGAAWV---------- 415 Query: 71 PYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDG 130 + RLG A +V+ +S ++ V +A V LLDG Sbjct: 416 -------LRSQLKQALERLG-TAERYVLTCGSSLLARFAVAEV----QALSGKPVFLLDG 463 Query: 131 GLRHWLRQNLPLSSGKS---QPAPAEFRAQLD 159 G W+ LP G+S P +R + Sbjct: 464 GTSAWVAAGLPTEDGESLLASPRIDRYRRPYE 495 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 50/296 (16%), Positives = 78/296 (26%), Gaps = 68/296 (22%) Query: 2 ASPQLCR-ALVSAQWVAEALRAPRAGQPLQ------LLDASWYLPKLGRDARREFEERHI 54 A +L R V ++ E + A R L LLDA L E++ I Sbjct: 104 AGGELFRDVNVPSKAFGELVEAERHTPSLAAEEVQALLDARAEAVILDARRFDEYQTMSI 163 Query: 55 PGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVW 114 PG L T V++ A Sbjct: 164 PGGISV-----------------PGAELVLRVAELAPDPRTRVIVNCAGRTRSIIGT--- 203 Query: 115 WMFRAFGHHA-VSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDI---- 169 G V+ L G W L G+++ A + A + Sbjct: 204 QSLLNAGIPNPVAALRNGTIGWTLAGQQLEHGQTRRFGAISQDTRKAAAQRARAVADRAG 263 Query: 170 KENL-----------ESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLS 218 E L R ++D R + E GH+PG+ + P + Sbjct: 264 VERLDLAGLAQWQDEHDRTTYLLDVRTPEEY-----------EAGHLPGSRSTPGGQLVQ 312 Query: 219 QEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDG 274 + + + + + V + GV A A G V + DG Sbjct: 313 E------TDHVASVRGARLVLVDDD-------GVRANMSASWLAQMGWQ-VAVLDG 354 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 81/249 (32%), Gaps = 64/249 (25%) Query: 41 LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIY 100 L E+E H+PG+ R++P ++ +H A V A V++ Sbjct: 286 LDVRTPEEYEAGHLPGS----------RSTPGGQLVQETDHVAS------VRGARLVLVD 329 Query: 101 DASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP 160 D + SA + M G + + L S + A L Sbjct: 330 DDGVRANMSASWLAQM--------------GWQVAVLDGL---SEADFSERGAWSAPLPR 372 Query: 161 AFIKTYED---IKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFL 217 D + + L +V+D A+ + HIPG + Sbjct: 373 QPRADTIDPTTLADWLGEPGTRVLDFTASANYAKR-----------HIPGAA---W---- 414 Query: 218 SQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACH-VALGAYLCGKPDVPIYDGSW 276 + +S +++ + ++ V TCGS + A VA L GKP V + DG Sbjct: 415 ----VLRS--QLKQALERLGT--AERYVLTCGSSLLARFAVAEVQALSGKP-VFLLDGGT 465 Query: 277 VEWYMRARP 285 W P Sbjct: 466 SAWVAAGLP 474 >1TQ1-A nrPDB Length = 129 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 14/105 (13%) Query: 181 VDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL 240 +D R F GH G +N+P+ + G+ K+ + + + Sbjct: 36 LDVRTPEEFS-----------QGHACGAINVPYMNR-GASGMSKNTDFLEQVSSHFG--Q 81 Query: 241 SKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARP 285 S ++ C SG + G V G + W P Sbjct: 82 SDNIIVGCQSGGRSIKATTDLLHAGFTGVKDIVGGYSAWAKNGLP 126 >2JTQ-A nrPDB Length = 85 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 27/94 (28%), Gaps = 24/94 (25%) Query: 181 VDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL 240 +D R +++ H+ G +NIP +E++ D Sbjct: 5 IDVRVPEQYQQE-----------HVQGAINIPL-------------KEVKERIATAVPDK 40 Query: 241 SKPLVATCGSGVTACHVALGAYLCGKPDVPIYDG 274 + + C +G + G V G Sbjct: 41 NDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGG 74 >1C25-A nrPDB Length = 161 Score = 35.9 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 40/124 (32%), Gaps = 38/124 (30%) Query: 176 RRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQE 235 + F ++D R + G GHI G VN+ EE+ + Sbjct: 43 KEFVIIDCRYPYEYEG-----------GHIKGAVNLHM------------EEEVEDFLLK 79 Query: 236 KKVDLSKP----LVATC----GSGVTACHVALGAYLCG-------KPDVPIYDGSWVEWY 280 K + + +V C G C G P++ + G + E++ Sbjct: 80 KPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFF 139 Query: 281 MRAR 284 M+ + Sbjct: 140 MKCQ 143 >3NTA-A nrPDB Length = 574 Score = 34.0 bits (76), Expect = 0.078, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 28/99 (28%) Query: 160 PAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQ 219 A ++ I E + ++D R G ++ G + G VNIP Sbjct: 471 DATPIHFDQIDNLSEDQ--LLLDVRNPGE-----------LQNGGLEGAVNIP------- 510 Query: 220 EGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVA 258 +E+R E + K ++ C G+ Sbjct: 511 ------VDELRDRMHE--LPKDKEIIIFCQVGLRGNVAY 541 >1QB0-A nrPDB Length = 211 Score = 34.0 bits (76), Expect = 0.079, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 25/72 (34%), Gaps = 18/72 (25%) Query: 177 RFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEK 236 +F +VD R + G GHI VN+P + L KSP Sbjct: 65 KFVIVDCRYPYEYEG-----------GHIKTAVNLPLERDA-ESFLLKSP------IAPC 106 Query: 237 KVDLSKPLVATC 248 +D L+ C Sbjct: 107 SLDKRVILIFHC 118 >1GN0-A nrPDB Length = 108 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 33/119 (27%), Gaps = 26/119 (21%) Query: 168 DIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPE 227 D + L+ + +VD R F GH ++ Sbjct: 11 DAHQKLQEKEAVLVDIRDPQSFA-----------MGHAVQAFHL--------------TN 45 Query: 228 EIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPE 286 + F D P++ C G ++ A G V DG + W + E Sbjct: 46 DTLGAFMRDN-DFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAE 103 >4WH9-A nrPDB Length = 183 Score = 32.1 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 20/50 (40%), Gaps = 12/50 (24%) Query: 177 RFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSP 226 +F +VD R + G GHI VN+P + L KSP Sbjct: 52 KFVIVDCRYPYEYEG-----------GHIKTAVNLPLERDA-ESFLLKSP 89 >6HIZ-Ci nrPDB Length = 181 Score = 32.1 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 147 SQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRA-TGRFRGTEPEPRDGIEPGHI 205 + P P R L A + +++ E +Q+ D R+ + F+ P + PG+ Sbjct: 22 TLPVPCAQRWDLRLARARIFQEYIEEKAPGAWQLEDERSMSPEFKTFTGYPMRDMRPGY- 80 Query: 206 PGTVNIP 212 N+P Sbjct: 81 --GQNLP 85 >5E7P-A nrPDB Length = 745 Score = 32.1 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 14/125 (11%) Query: 81 HFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGG--LRHWLRQ 138 + RLG+ V++Y G R + G +V + G + W+ Sbjct: 506 QHPDTFSRLGIDPPRGVLLYGPPGCGKTFVVRA---LASSGRLSVHAVKGSELMDKWV-- 560 Query: 139 NLPLSSGKSQPAPAEFRAQLDP-AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPR 197 G S+ A E A+ A + D + L RR Q DS T + + Sbjct: 561 ------GSSEKAVRELFARARDSAPSLVFLDEIDALAPRRGQNFDSGVTDKVVASLLTEL 614 Query: 198 DGIEP 202 DGIEP Sbjct: 615 DGIEP 619 >4AEE-A nrPDB Length = 696 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 22/71 (30%), Gaps = 9/71 (12%) Query: 68 RTSPYDHML----PGAEHFAEYA-----GRLGVGAATHVVIYDASDQGLYSAPRVWWMFR 118 SPY M P + E G + + Y +++ Y A W+ Sbjct: 352 ENSPYWEMFSFLSPPPKEIVELMLKYIDGEECRSRELYKLDYFRNNKPFYEAFFNIWLMA 411 Query: 119 AFGHHAVSLLD 129 F H +D Sbjct: 412 KFNHDNPRTVD 422 >3EKG-A nrPDB Length = 404 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 24/57 (42%) Query: 183 SRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVD 239 R +F T P + G I G + + +EGL+K+ EE+ + + D Sbjct: 154 VRDELQFYATGARPDLAQKMGFIGGKMPLHHGPSEGEEGLKKNLEELATMRERVGPD 210 >3CSQ-A nrPDB Length = 334 Score = 29.8 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 28/90 (31%), Gaps = 12/90 (13%) Query: 62 IDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAAT-----HVVIYDASDQGLYS------- 109 I + SP + + G G+G H + D + ++ Sbjct: 241 ITWVNVHESPLPFDVGKKLKKGDLMGHTGIGGNVTGDHWHFNVIDGKEYQGWTKKPDSCL 300 Query: 110 APRVWWMFRAFGHHAVSLLDGGLRHWLRQN 139 A ++ F + V +++G W + Sbjct: 301 AGTELHIYDVFAVNNVEIINGNGYDWKTSD 330 >2ZIV-A nrPDB Length = 311 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 22/61 (36%), Gaps = 6/61 (9%) Query: 124 AVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDS 183 V L+ G W+ + P P + R + + Y ++ ++ ++D Sbjct: 52 DVRKLNVGDFLWVA------RERVTPVPGQLRPPVGKELVLDYIIERKRMDDLCGSIIDG 105 Query: 184 R 184 R Sbjct: 106 R 106 >1C4O-A nrPDB Length = 664 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 53/164 (32%), Gaps = 26/164 (15%) Query: 130 GGLRHWLRQNLPLSSGKSQPAPAEFR-----------AQLDPAFIKTYEDIKENLESRRF 178 G R + +NL + GK P L P + ++ E + Sbjct: 145 GDPREYRARNLVVERGKPYPREVLLERLLELGYQRNDIDLSPGRFRAKGEVLEIFPAYET 204 Query: 179 QVVDSRATGRF--RGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPE-------EI 229 + + G R ++ P G +PG V P T +LS EGLE+ + E Sbjct: 205 EPIRVELFGDEVERISQVHPVTGERLRELPGFVLFPATHYLSPEGLEEILKEIEKELWER 264 Query: 230 RHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGK-PDVPIY 272 F+E+ ++ + + G P V Y Sbjct: 265 VRYFEERG-----EVLYAQRLKERTLYDLEMLRVMGTCPGVENY 303 >5GTM-A nrPDB Length = 601 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 31/94 (32%), Gaps = 7/94 (7%) Query: 154 FRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPF 213 R IK +E+ + + ++ D RA G + + H I + Sbjct: 448 VRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEK------LIRLHFQDEQ-IVY 500 Query: 214 TDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVAT 247 F S + S EEI + SK + + Sbjct: 501 GAFQSSSATDSSMEEIFQHLMAYHQEASKRISSH 534 >6J5C-A nrPDB Length = 401 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 21/56 (37%) Query: 52 RHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGL 107 H+P A D +D P+ H + AE G A + +Y+ DQ Sbjct: 207 EHLPTAWQVHRDWFNDLALPWKHDGNPHWNNAERLVEFGAPHAVKMDVYNLGDQTG 262 >5NPF-A nrPDB Length = 798 Score = 28.6 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Query: 9 ALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDR 68 A + W+A A G+ L+ +A + + A++ FE+ + +++ D SD Sbjct: 586 AYCGSLWLAALKAAQEIGKVLKDNEAYIKYNEWYKIAQQNFEKE-LWNGEYYNFDTESDH 644 Query: 69 TSPYDHMLPGAEHFAEYAGRLGVGAATHV 97 + +A+ + HV Sbjct: 645 KDSIMADQLAGQWYADILRLGDILPKDHV 673 >1CX1-A nrPDB Length = 153 Score = 27.1 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 28/91 (30%), Gaps = 3/91 (3%) Query: 185 ATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPL 244 + +EP DG +PG P+ L G+ E L P+ Sbjct: 21 PWSLYGTSEPVFADGRMCVDLPGGQGNPWDAGLVYNGVPVGEGESYVLSFTASATPDMPV 80 Query: 245 VATCGSGVTACHVAL---GAYLCGKPDVPIY 272 G G A A A L G+P Y Sbjct: 81 RVLVGEGGGAYRTAFEQGSAPLTGEPATREY 111 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.124 0.345 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,702,163 Number of Sequences: 36641 Number of extensions: 452633 Number of successful extensions: 1391 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1252 Number of HSP's gapped (non-prelim): 70 length of query: 297 length of database: 10,336,785 effective HSP length: 96 effective length of query: 201 effective length of database: 6,819,249 effective search space: 1370669049 effective search space used: 1370669049 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 58 (27.0 bits)