BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P25144 (334 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3OQN-A nrPDB 677 0.0 1RZR-D nrPDB 538 e-153 2O20-A nrPDB 333 8e-92 2PUG-A nrPDB 187 5e-48 3DBI-A nrPDB 169 1e-42 5YSZ-A nrPDB 155 2e-38 3H5O-A nrPDB 144 5e-35 3BIL-A nrPDB 138 3e-33 5UFH-A nrPDB 133 1e-31 3E3M-A nrPDB 130 5e-31 3EDC-A nrPDB 129 2e-30 3CTP-A nrPDB 127 6e-30 4O5A-A nrPDB 123 1e-28 6NDI-A nrPDB 117 1e-26 3KJX-A nrPDB 107 9e-24 3JVD-A nrPDB 100 1e-21 3H5T-A nrPDB 94 1e-19 3TB6-A nrPDB 84 1e-16 2IKS-A nrPDB 78 6e-15 3GYB-A nrPDB 75 3e-14 1OSL-A nrPDB 55 6e-08 4FE4-A nrPDB 52 4e-07 5OCP-A nrPDB 49 3e-06 4XXH-A nrPDB 49 3e-06 1DBP-A nrPDB 47 2e-05 4ZJP-A nrPDB 42 3e-04 4WUT-A nrPDB 40 0.001 3O75-A nrPDB 40 0.002 1UXC-A nrPDB 36 0.018 2L8N-A nrPDB 35 0.030 4P2B-A nrPDB 30 1.7 3IGH-X nrPDB 29 2.3 3T4E-A nrPDB 29 2.8 4WZZ-A nrPDB 28 4.5 5EY9-A nrPDB 28 5.2 3MMT-A nrPDB 28 6.6 1UQW-A nrPDB 28 6.7 4DU5-A nrPDB 27 8.4 6AP1-H nrPDB 27 9.2 >3OQN-A nrPDB Length = 339 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/332 (100%), Positives = 332/332 (100%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT Sbjct: 2 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 61 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV Sbjct: 62 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 121 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA Sbjct: 122 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 181 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT Sbjct: 182 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 241 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA Sbjct: 242 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 301 Query: 303 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 334 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS Sbjct: 302 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 333 >1RZR-D nrPDB Length = 332 Score = 538 bits (1387), Expect = e-153, Method: Compositional matrix adjust. Identities = 252/331 (76%), Positives = 292/331 (88%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 N+TIYDVAREA+VSMATVSRVVNGNPNVKP+TRKKVLE IERLGYRPNAVARGLASKKTT Sbjct: 2 NVTIYDVAREASVSMATVSRVVNGNPNVKPSTRKKVLETIERLGYRPNAVARGLASKKTT 61 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TVGVIIPDIS+IFY+ELARGIEDIATMYKYNIILSNSDQN +KELHLLN MLGKQVDGI+ Sbjct: 62 TVGVIIPDISNIFYAELARGIEDIATMYKYNIILSNSDQNQDKELHLLNNMLGKQVDGII 121 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 FM GN+T+EHV E K+SPVP+VLAAS+E + PSV IDYEQA +DAV+ L+D GH +IA Sbjct: 122 FMSGNVTEEHVEELKKSPVPVVLAASIESTNQIPSVTIDYEQAAFDAVQSLIDSGHKNIA 181 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 FVSG + EPIN +KK++GYKRAL E+ LP + ++ EGDYTYDSG+EA++ L+ D+KPT Sbjct: 182 FVSGTLEEPINHAKKVKGYKRALTESGLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPT 241 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 AI TDEMALG+IH AQD+GL++P DL+IIGFDNTRLS MVRPQL++VVQP YDIGAVA Sbjct: 242 AIFVGTDEMALGVIHGAQDRGLNVPNDLEIIGFDNTRLSTMVRPQLTSVVQPMYDIGAVA 301 Query: 303 MRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 MRLLTK MNKE V+ IV+LPHRIE R+STK Sbjct: 302 MRLLTKYMNKETVDSSIVQLPHRIEFRQSTK 332 >2O20-A nrPDB Length = 332 Score = 333 bits (853), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 168/332 (50%), Positives = 236/332 (71%), Gaps = 3/332 (0%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 S TIYDVAR A VSMATVSRVVNGN NVK TR+KVLEAI L YRPNAVARGLASK+T Sbjct: 4 STTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRT 63 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 TTVGVI+P I+S +++ + RG++DIA+MYKYN+IL+NSD ++EKE +L T L KQVDGI Sbjct: 64 TTVGVILPTITSTYFAAITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQVDGI 123 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 V+MG ++ ++ K S P+VL +++ +E PSV IDY A Y + K L+D G+ I Sbjct: 124 VYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTKKLIDSGNKKI 183 Query: 182 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 A++ G + + + ++++ GY+ AL EAN+ F+E V EG+Y+Y+ G + L L++ Sbjct: 184 AYIMGSLKD-VENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERL--LERGA 240 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 T+ + + D +A+G++ A D+G+ +PED +II N+ ++ P L++V QP YD+GAV Sbjct: 241 TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAV 300 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 AMRLLTKLM KE VE++ + L H I R+STK Sbjct: 301 AMRLLTKLMLKEDVEQNQLVLDHEIFSRRSTK 332 >2PUG-A nrPDB Length = 340 Score = 187 bits (475), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 113/341 (33%), Positives = 178/341 (52%), Gaps = 30/341 (8%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 TI DVA+ ANVS TVS V+N V TR V AI+ L Y P+AVAR L T ++ Sbjct: 2 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 61 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 G++ + +++E+ +E Y +IL N+ N+EK+ L+ M K+VDG++ M Sbjct: 62 GLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVM 121 Query: 125 GGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYD---------------A 169 S P L A +EE P V +D+ +A D A Sbjct: 122 C-------------SEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMA 168 Query: 170 VKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLE 229 + L+++GH +I + GP+ E + +L G+ +A+EEA + E ++ +GD+ +SG Sbjct: 169 GRYLIERGHREIGVIPGPL-EQNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYR 227 Query: 230 ALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLS 289 A+Q ++S +PTA+ D MA+G + AA + GL +P+D+ +IG+DN R + P L+ Sbjct: 228 AMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALT 287 Query: 290 TVVQPTYDIGAVAMR-LLTKLMNKEPVEEHIVELPHRIELR 329 T+ QP +G A LL +++NK + I P IE R Sbjct: 288 TIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERR 328 >3DBI-A nrPDB Length = 338 Score = 169 bits (429), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 97/304 (31%), Positives = 177/304 (58%), Gaps = 10/304 (3%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 MS T+ +VA+ A VS ATVSRV++GN V T+ +V +A+E GYRPN +AR L++K Sbjct: 1 MSLTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESGYRPNLLARNLSAKS 60 Query: 61 TTTVGVIIPDI--SSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQV 118 T T+G+++ + I++SEL +A ++L++ + E+E + +L + Sbjct: 61 TQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHSAEEERQAIQYLLDLRC 120 Query: 119 DGIV----FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLV 174 D I+ F+ + D+ + + PI++ + + SV D++Q ++AV L+ Sbjct: 121 DAIMIYPRFLSVDEIDDIIDAHSQ---PIMVLNRRLRKNSSHSVWCDHKQTSFNAVAELI 177 Query: 175 DKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHL 234 + GH +IAF++G M P + ++L GYK AL + + NE+ +A G +T SG E ++ L Sbjct: 178 NAGHQEIAFLTGSMDSPTS-IERLAGYKDALAQHGIALNEKLIANGKWTPASGAEGVEML 236 Query: 235 MSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQP 294 + K +A++++ D+MA+G + A ++G+++PE + +IGFD+ ++ P LS+V P Sbjct: 237 LERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFDDIAIAPYTVPALSSVKIP 296 Query: 295 TYDI 298 ++ Sbjct: 297 VTEM 300 >5YSZ-A nrPDB Length = 360 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 102/322 (31%), Positives = 169/322 (52%), Gaps = 15/322 (4%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 T+ VA A V TVSRV+NG+ V P TR+ V AI+ LGY PN AR L +++T TV Sbjct: 28 TLEMVAALAGVGRGTVSRVINGSDQVSPATREAVKRAIKELGYVPNRAARTLVTRRTDTV 87 Query: 65 GVIIPD-----ISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVD 119 +++ + + FY+ + G+ + + +L+ +E E L + G+ VD Sbjct: 88 ALVVSENNQKLFAEPFYAGIVLGVGVALSERGFQFVLATGRSGIEHE-RLGGYLAGQHVD 146 Query: 120 GIVFMGGNITDEHVAEFKRSPVPIVLAA---SVEEQEETPSVAIDYEQAIYDAVKLLVDK 176 G++ + + D + VP V V E E+ V ID A + L++ Sbjct: 147 GVLLLSLHRDDPLPQMLDEAGVPYVYGGRPLGVPE-EQVSYVDIDNIGGGRQATQRLIET 205 Query: 177 GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMS 236 GH IA ++GP + + ++LQGY+ AL A + ++E V+ GD+TYDSG+ A++ L Sbjct: 206 GHRRIATIAGPQ-DMVAGVERLQGYREALLAAGMEYDETLVSYGDFTYDSGVAAMREL-- 262 Query: 237 LDKKP--TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQP 294 LD+ P A+ +A+D M L + + G +PED+ ++G+D++ ++ P +++V QP Sbjct: 263 LDRAPDVDAVFAASDLMGLAALRVLRASGRRVPEDVAVVGYDDSTVAEHAEPPMTSVNQP 322 Query: 295 TYDIGAVAMRLLTKLMNKEPVE 316 T +G RLL + E E Sbjct: 323 TELMGREMARLLVDRITGETTE 344 >3H5O-A nrPDB Length = 339 Score = 144 bits (363), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 97/336 (28%), Positives = 169/336 (50%), Gaps = 12/336 (3%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 +T++DVA+ A VS TVSRV+N V R+KV++A++ L Y P+ A LAS K+ Sbjct: 4 GVTMHDVAKAAGVSAITVSRVLNQPQQVSEQLREKVMQAVDALAYVPSRSASTLASAKSR 63 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TV V+IP +++ + E GIE + Y +++ NS + +EL LL L + DG++ Sbjct: 64 TVLVLIPSLANTVFLETLTGIETVLDAAGYQMLIGNSHYDAGQELQLLRAYLQHRPDGVL 123 Query: 123 FMGGNITDEHVAEFKR----SPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 G + H F+R +P+V + + V E A + L+ +G Sbjct: 124 ITGLS----HAEPFERILSQHALPVVYMMDLADDGRC-CVGFSQEDAGAAITRHLLSRGK 178 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSL 237 I F+ + E + K+L GY+ AL+ A+ +++ + G + L ++ Sbjct: 179 RRIGFLGAQLDERV--MKRLDGYRAALDAADCRDAGLEWLDPQPSSMQMGADMLDRALAE 236 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 A+ D++A+G + +Q G+++PE L I GF++ + + P L+TV P D Sbjct: 237 RPDCDALFCCNDDLAIGALARSQQLGIAVPERLAIAGFNDLQPAAWCTPPLTTVATPRRD 296 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 IG A + L +L++ E +L R+ LR+S++ Sbjct: 297 IGVHAAKALLQLIDGEEPASRRADLGFRLMLRRSSE 332 >3BIL-A nrPDB Length = 348 Score = 138 bits (348), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 92/307 (29%), Positives = 154/307 (50%), Gaps = 6/307 (1%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 T+ DVAR+A VS+AT SR + NP V +TR+++ + LGYR NA AR L S ++ T+ Sbjct: 10 TLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARALRSSRSNTI 69 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 GVI+P + + +++ + I+ A+ I++NS+++ L + VDGI+ + Sbjct: 70 GVIVPSLINHYFAAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHGVDGIICV 129 Query: 125 GGNITDEHVAEFKRSPVPIVLAASVEEQEET-PSVAIDYEQAIYDAVKLLVDKGHTDIAF 183 + + ++ +P+VL + T P+ + + I AV+LL I + Sbjct: 130 PNEECANQLEDLQKQGMPVVLVDRELPGDSTIPTATSNPQPGIAAAVELLAHNNALPIGY 189 Query: 184 VSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTA 243 +SGPM R ++L+ +K A AN EQ V G Y G E L LD+ Sbjct: 190 LSGPMDTSTGR-ERLEDFKAAC--ANSKIGEQLVFLGGYEQSVGFEGATKL--LDQGAKT 244 Query: 244 ILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAM 303 + + M +G+I A GL I +D+ +IGFD L + L+ + Q + A+ Sbjct: 245 LFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQRAV 304 Query: 304 RLLTKLM 310 +LT+L+ Sbjct: 305 SILTELI 311 >5UFH-A nrPDB Length = 347 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 91/299 (30%), Positives = 143/299 (47%), Gaps = 11/299 (3%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 +TI DVA EA VS TVS V+NG +++ +TR +VLEA+++L Y N AR L + T Sbjct: 7 GVTIKDVAAEAGVSFKTVSNVINGTGSMRESTRGRVLEAMDKLNYTINLSARSLKTGTTG 66 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 +G+ I D S F S LA I A + Y +I++ QN + DG + Sbjct: 67 LLGLAIFDFSQPFASYLADQIIVCAREHHYGVIINTYGQNEHGLARAMRQANNLAADGWI 126 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 + +H +S P+VL + + V + +A+ L+D G+ IA Sbjct: 127 VFADHAMGQHSKMLDQS-YPLVLTGDWDAYGKVDQVTMPNVEAMRYTTNRLLDSGYRSIA 185 Query: 183 FVS--GPMAEPINRSK-------KLQGYKRALEEANLPFN-EQFVAEGDYTYDSGLEALQ 232 G + R ++QGY +A EE + + + G T DSG+ A Sbjct: 186 LFGADGSLGARHYRQATEGTQELRVQGYMQAYEEHGIEARMDMLFSGGLLTSDSGVRATN 245 Query: 233 HLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTV 291 +M +P AI+ D MALG +H Q +G+ +P+D+ ++GFDN + P L+T+ Sbjct: 246 LMMDQGVRPDAIICLNDAMALGALHQLQVRGIRVPDDVQVVGFDNVPEATYANPSLTTI 304 >3E3M-A nrPDB Length = 355 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 89/339 (26%), Positives = 174/339 (51%), Gaps = 12/339 (3%) Query: 4 ITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTT 63 +T+ DVA+ A VS TVSR + + + TR+++L+ ++ + Y P+ VA L +K++ Sbjct: 13 VTMRDVAKAAGVSRMTVSRALKKDSPISSETRERILKVVKDMNYVPDQVAGSLTTKRSGF 72 Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVF 123 VG+++P ++++ +++ A+ + D+ ++L + + E+E L+ TML ++ + +V Sbjct: 73 VGLLLPSLNNLHFAQTAQSLTDVLEQGGLQLLLGYTAYSPEREEQLVETMLRRRPEAMVL 132 Query: 124 MGGNITDEHVAEFKRSPVPIVLAASVEEQEETP---SVAIDYEQAIYDAVKLLVDKGHTD 180 T++ + +R+ +PIV + E+ P +V E+A YD L+ +G Sbjct: 133 SYDGHTEQTIRLLQRASIPIV---EIWEKPAHPIGHTVGFSNERAAYDMTNALLARGFRK 189 Query: 181 IAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSLDK 239 I F+ + + + G+KRA+ EA L P E + + + G+ A + ++ Sbjct: 190 IVFLGEKDDDWTRGAARRAGFKRAMREAGLNPDQEIRLGAPPLSIEDGVAAAELILQEYP 249 Query: 240 KPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTV-VQPT--- 295 I +D A G++ + G+++PE + ++GF N +S P++STV V P Sbjct: 250 DTDCIFCVSDMPAFGLLSRLKSIGVAVPEQVSVVGFGNFEVSRFASPEISTVRVDPIAIG 309 Query: 296 YDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 334 + G++ +RLL +HI LP +E R S K+ Sbjct: 310 RETGSLILRLLDPKQRSPQTAQHIT-LPPVLEFRPSLKN 347 >3EDC-A nrPDB Length = 360 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 100/335 (29%), Positives = 174/335 (51%), Gaps = 9/335 (2%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 M +T+YDVA A VS TVSRVVN +V TR+KV A+ L Y PN VA+ LA K+ Sbjct: 1 MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQ 60 Query: 61 TTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQN-MEKELHLLNTMLGKQVD 119 + +GV ++ S++ I+ A ++++S +++ +E ++ +L ++V Sbjct: 61 SLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVS 120 Query: 120 GIVF-MGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 G++ + D E + VP L V +Q S+ +E V+ LV GH Sbjct: 121 GLIINYPLDDQDAIAVEAACTNVP-ALFLDVSDQTPINSIIFSHEDGTRLGVEHLVALGH 179 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSL 237 IA ++GP++ ++ +L G+ + L + P E+ EGD++ SG + +++ Sbjct: 180 QQIALLAGPLSS-VSARLRLAGWHKYLTRNQIQPIAER---EGDWSAMSGFQQTMQMLNE 235 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 PTA+L A D+MALG + A + GL + D+ ++G+D+T S P L+T+ Q Sbjct: 236 GIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRL 295 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 +G ++ L +L + V+ + + LP + RK+T Sbjct: 296 LGQTSVDRLLQLSQGQAVKGNQL-LPVSLVKRKTT 329 >3CTP-A nrPDB Length = 330 Score = 127 bits (320), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 91/324 (28%), Positives = 167/324 (51%), Gaps = 18/324 (5%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 I ++A+ A +S+ATVSR +N V R+K+ + ++ L Y PNA+AR + +K + T+ Sbjct: 4 NIREIAKRAGISIATVSRHLNNTGYVSEDAREKIQKVVDELNYTPNALARAMFTKNSKTI 63 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 G+++P+IS+ F++++A IE+ A Y + L N+D + EKE L + +V GI+ Sbjct: 64 GLMVPNISNPFFNQMASVIEEYAKNKGYTLFLCNTDDDKEKEKTYLEVLQSHRVAGIIAS 123 Query: 125 GGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAFV 184 D E+ +P+V A + +++ D A L +KG I + Sbjct: 124 RSQCED----EYANIDIPVV-AFENHILDNIITISSDNYNGGRMAFDHLYEKGCRKILHI 178 Query: 185 SGP---MAEPINRSKKLQGYK-RALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKK 240 GP A + L G + + LE + F F + + + +++ +++ D Sbjct: 179 KGPEVFEATELRYKGFLDGARAKDLEIDFIEFQHDFQVK---MLEEDINSMKDIVNYD-- 233 Query: 241 PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGA 300 I D A ++ A + +G+SIP+++ IIGFDN+ + ++ P L+T+ QP + Sbjct: 234 --GIFVFNDIAAATVMRALKKRGVSIPQEVQIIGFDNSFIGELLYPSLTTINQPIEALAY 291 Query: 301 VAMRLLTKLMNKEPV--EEHIVEL 322 + LL K++N E V E++I+E+ Sbjct: 292 TIIELLIKIINGEGVLIEDYIMEV 315 >4O5A-A nrPDB Length = 345 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 99/340 (29%), Positives = 174/340 (51%), Gaps = 17/340 (5%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 + +TI+DVA+ + VS + VS +NG P V TR+KVL+ +LG+RPN A+ LA +T Sbjct: 9 AKVTIFDVAKASGVSSSAVSYALNGKPGVSDATREKVLQVARKLGWRPNGAAQSLAQSRT 68 Query: 62 TTVGVII---PDISSI--FYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGK 116 +G+++ P + S + L G+ Y++++ S + ++ L + + Sbjct: 69 RRIGLVLGYDPQLLSAEPYIMRLISGLGSALEERDYSLLVRMSMDDDDEVSILEDWIATG 128 Query: 117 QVDGIVFMGGNITDEHVAEFKRSP-VPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVD 175 VD ++ + I D + K +P +P + A P++ D A ++ L Sbjct: 129 NVDALLLLNLEIGDPRIELMKNNPQMPCLALADSSLTSGLPTLMSDDAAASGTMIRHLAL 188 Query: 176 KGHTDIAFVSGPMAEPINRSKKLQGYKR--ALEEANLPFNEQF-VAEGDYTYDSGLEALQ 232 GH +IA V+GP E + S Y R A E ++ DYT +SG EA + Sbjct: 189 FGHKNIARVAGP--EELGHS-----YIRDAAFSEITTELGMRYRCLHTDYTPESGAEATK 241 Query: 233 HLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVV 292 L+S++ +PTAI+ D MAL A +G+ +PEDL II + ++ +++ P ++ + Sbjct: 242 RLLSVEPRPTAIIYDNDVMALAGESVASVKGVRVPEDLSIISWGDSFMNVAAHPPITALS 301 Query: 293 QPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 + + G +A +L+ KL++ E V E++ E P+ + R ST Sbjct: 302 RNILESGRLAAQLMLKLIDGEDV-ENVEEPPYELIERAST 340 >6NDI-A nrPDB Length = 334 Score = 117 bits (292), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 94/305 (30%), Positives = 149/305 (48%), Gaps = 15/305 (4%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT-- 62 ++ DVA+ ANVS+ TVSR +N +KP T +V AI Y P+ A+ + + T Sbjct: 6 SLKDVAKLANVSLMTVSRALNTPERLKPETLARVQAAIAETNYVPDLSAKKIRGARATPS 65 Query: 63 TVGVIIPD-ISSIFYSELARGIEDIATMYKYNIILSN--SDQNMEKELHLLNTMLGKQVD 119 T+GV+ D +++ F E+ IE+ A + +N + N SD E + LL L + D Sbjct: 66 TIGVLALDTVTTPFSVEITLSIEETARAHGWNSFVVNMFSDDRPEAVVDLL---LSHRPD 122 Query: 120 GIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHT 179 GI+F + + E K +P VLA + S D EQ YDAVK L+ G+ Sbjct: 123 GIIFTTMGLRQVPLPE-KLLTLPCVLANCESLSQPVASYIPDDEQGQYDAVKALLAAGYR 181 Query: 180 DIAFVSGPMAEPINRSKKLQGYKRALEEANLP---FNEQFVAEGDYTY-DSGLEALQHLM 235 + P ++P ++ +G +RA EA + + ++ +GD Y D L H+ Sbjct: 182 RPLCLHLPASQPATIRRR-RGLERACREAGIEPDHLSHSYMGQGDEHYHDIPAVVLAHIR 240 Query: 236 SLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDN-TRLSLMVRPQLSTVVQP 294 +++ D +A + QGL IP+D+ ++G+DN + + P LSTV P Sbjct: 241 EGKPGFDSVICGNDRIAFMVYQTLLGQGLRIPQDVAVVGYDNMVGIGDLFLPPLSTVQLP 300 Query: 295 TYDIG 299 YDIG Sbjct: 301 HYDIG 305 >3KJX-A nrPDB Length = 344 Score = 107 bits (266), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 82/325 (25%), Positives = 149/325 (45%), Gaps = 5/325 (1%) Query: 4 ITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTT 63 +T+ DV+ + VS TVSRV+ +V TR +VL A + LGY PN +A LAS + Sbjct: 11 LTLRDVSEASGVSEMTVSRVLRNRGDVSDATRARVLAAAKELGYVPNKIAGALASNRVNL 70 Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVF 123 V VIIP +S++ + E+ GI + + ++ +D EKE +L ML + G++ Sbjct: 71 VAVIIPSLSNMVFPEVLTGINQVLEDTELQPVVGVTDYLPEKEEKVLYEMLSWRPSGVII 130 Query: 124 MGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAF 183 G ++ A + +P+V + + V I + +A + + ++ G+ I F Sbjct: 131 AGLEHSEAARAMLDAAGIPVVEIMDSDGKPVDAMVGISHRRAGREMAQAILKAGYRRIGF 190 Query: 184 VSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTA 243 + M K+ +G+ L + + ++ G G E Q ++ Sbjct: 191 MGTKMPLDYRARKRFEGFTEVLGKNGVEIEDREFYSGGSALAKGREMTQAMLERSPDLDF 250 Query: 244 ILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAM 303 + + D +A G + +QG+ IP + + GF+N L + +L+T+ +IG A Sbjct: 251 LYYSNDMIAAGGLLYLLEQGIDIPGQIGLAGFNNVELLQGLPRKLATMDACRLEIGRKAA 310 Query: 304 RLLTKLMNKEPVEEHIVELPHRIEL 328 ++ K + E+ E+ RI L Sbjct: 311 EIIAKRL-----EDPEAEIETRITL 330 >3JVD-A nrPDB Length = 333 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 86/331 (25%), Positives = 163/331 (49%), Gaps = 18/331 (5%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 ++ +VA A V AT SR ++G V P TR+KV A + L Y PN +A+ L ++ V Sbjct: 8 SLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALREHRSALV 67 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 GVI+PD+S+ +YSE + I+ Y ++++ ++ +++ ++ +++ Q GI+ + Sbjct: 68 GVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDV-VMESLISIQAAGIIHV 126 Query: 125 G--GNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 G+I E +P+V E P V D E + + ++ +IA Sbjct: 127 PVVGSIAPEG--------IPMVQLTRGELGPGFPRVLCDDEAGFFQLTESVLGGSGMNIA 178 Query: 183 FVSGPMAEPINRSK-KLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 + G E ++ ++ +++G A A++ E G Y+ +SG E Q + + + P Sbjct: 179 ALVG--EESLSTTQERMRGISHA---ASIYGAEVTFHFGHYSVESGEEMAQVVFN-NGLP 232 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 A++ A+ + G++ A + +P D+ I G+D+ V ++T V P ++G Sbjct: 233 DALIVASPRLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKE 292 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 A+RLL L+ + V L ++ LR S+ Sbjct: 293 AVRLLVDLIENPELPTGDVVLQGQVILRGSS 323 >3H5T-A nrPDB Length = 366 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 83/344 (24%), Positives = 152/344 (44%), Gaps = 38/344 (11%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGY-RPNAVARGLASKKTTT 63 T+ +A + +S TVS N + R+++L+ E +GY P+ VAR L +++ Sbjct: 11 TLASIAAKLGISRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGA 70 Query: 64 VGVIIPDISSIFYSELAR-----GIEDIATMYKYNIILSNSDQNME--KELHLLNTMLGK 116 +GV++ + + + ++A G+ A + +I ++ +++ L+N Sbjct: 71 IGVLLTEDLTYAFEDMASVDFLAGVAQAAGDTQLTLIPASPASSVDHVSAQQLVNN---A 127 Query: 117 QVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDK 176 VDG+V D H+ + +P V+A +E P +A + +AI A + L+D Sbjct: 128 AVDGVVIYSVAKGDPHIDAIRARGLPAVIADQPAREEGMPFIAPNNRKAIAPAAQALIDA 187 Query: 177 GHTDIAFVSGPMAEPIN----------------RSKKLQGYKRALEEANL-----PFNEQ 215 GH I +S + N + +++G EA + P E Sbjct: 188 GHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVRGAMEVFIEAGIDPGTVPIMEC 247 Query: 216 FVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGF 275 ++ + + E + L+ TA+L D +A G++ + G S P DL + GF Sbjct: 248 WINNRQHNF----EVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSAPADLSLTGF 303 Query: 276 DNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHI 319 D T ++L L+TV+QP G A L K+++KE VE + Sbjct: 304 DGTHMALAR--DLTTVIQPNKLKGFKAGETLLKMIDKEYVEPEV 345 >3TB6-A nrPDB Length = 298 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/300 (25%), Positives = 145/300 (48%), Gaps = 18/300 (6%) Query: 46 GYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEK 105 G P A+ A T+GV+ IS + + RGIE + Y+++L++++ N + Sbjct: 1 GIDPFTSAKS-ALHSNKTIGVLTTYISDYIFPSIIRGIESYLSEQGYSMLLTSTNNNPDN 59 Query: 106 ELHLLNTMLGKQVDGIV-------FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSV 158 E L +L + +DG++ NI + +++ +P + + + PS Sbjct: 60 ERRGLENLLSQHIDGLIVEPTKSALQTPNIG--YYLNLEKNGIPFAMINASYAELAAPSF 117 Query: 159 AIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFV 217 +D + A + L+ GHT + + A+ K++ G+ +A E L P + V Sbjct: 118 TLDDVKGGMMAAEHLLSLGHTHMMGIFK--ADDTQGVKRMNGFIQAHRERELFPSPDMIV 175 Query: 218 AEGDYTYDSGL-EALQHLMSLDKK--PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIG 274 +S L E ++ + + K PTAIL DE+AL +I ++ L +PED+ I+G Sbjct: 176 TFTTEEKESKLLEKVKATLEKNSKHMPTAILCYNDEIALKVIDMLREMDLKVPEDMSIVG 235 Query: 275 FDNTRLSLMVRPQLSTVVQPTYDIG-AVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 +D++ + + +L++V P +G A A ++ L +K+P +E ++ P I +R+S + Sbjct: 236 YDDSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDCLEHKKPKQEDVIFEPELI-IRQSAR 294 >2IKS-A nrPDB Length = 293 Score = 77.8 bits (190), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 63/257 (24%), Positives = 119/257 (46%), Gaps = 10/257 (3%) Query: 47 YRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKE 106 Y PNAVA GL + +T ++G++IPD+ + Y+ +A +E A Y ++++ S+ + E Sbjct: 6 YHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNE 65 Query: 107 LHLLNTMLGKQVDGIVFMGGNITDEH--VAEFKRSPVPIV-LAASVEEQEETPSVAIDYE 163 + + +L +QVD I+ + ++ EH + P PIV L +++ + T V D + Sbjct: 66 MRCIEHLLQRQVDAII-VSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVVGADQD 124 Query: 164 QAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYT 223 A A +L K + G + E + QG++ A ++ P F+ Y Sbjct: 125 DAEMLAEEL--RKFPAETVLYLGALPELSVSFLREQGFRTAWKDD--PREVHFLYANSYE 180 Query: 224 YDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGF-DNTRLSL 282 ++ + + + P A+ + + + G++ + +P DL I F DN L Sbjct: 181 REAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDNELLDF 240 Query: 283 MVRPQLSTVVQPTYDIG 299 + P L+ V Q D+ Sbjct: 241 LQCPVLA-VAQRHRDVA 256 >3GYB-A nrPDB Length = 280 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 79/263 (30%), Positives = 127/263 (48%), Gaps = 22/263 (8%) Query: 58 SKKTTTVGVIIPDISSIFYSELARGIEDIAT--MYKYNIILSNSDQNMEKELHLLNTMLG 115 S +T + V+I D S+ ++ +L + + D+ T Y+ ++I S + Q + + L Sbjct: 2 SLRTQLIAVLIDDYSNPWFIDLIQSLSDVLTPKGYRLSVIDSLTSQAGTDPI---TSALS 58 Query: 116 KQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEET-PSVAIDYEQAIYDAVKLLV 174 + DGI+ + +I D V + S P V+A + Q T SVA D + A K L+ Sbjct: 59 MRPDGII-IAQDIPDFTVPD---SLPPFVIAGTRITQASTHDSVANDDFRGAEIATKHLI 114 Query: 175 DKGHTDIAFVSGPMAEPINRSKKLQGYKRA--LEEANLPFNEQFVAEGDYTYDSGLEALQ 232 D GHT IA + + R + + RA LE + + V YT + Sbjct: 115 DLGHTHIAHLRVGSGAGLRRFESFEATMRAHGLEPLSNDYLGPAVEHAGYT--------E 166 Query: 233 HLMSLDKKP--TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLST 290 L L + P TAI S+ D A+G + AA++ GL +PEDL IIG+DNT L+ L+T Sbjct: 167 TLALLKEHPEVTAIFSSNDITAIGALGAARELGLRVPEDLSIIGYDNTPLAQTRLINLTT 226 Query: 291 VVQPTYDIGAVAMRLLTKLMNKE 313 + + +G A LL +++ E Sbjct: 227 IDDNSIGVGYNAALLLLSMLDPE 249 >1OSL-A nrPDB Length = 62 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 30/61 (49%), Positives = 38/61 (62%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 M +T+YDVA A VS TVSRVVN +V TR+KV A+ L Y PN A+ LA K+ Sbjct: 1 MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRCAQQLAGKQ 60 Query: 61 T 61 + Sbjct: 61 S 61 >4FE4-A nrPDB Length = 392 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 63/211 (29%), Positives = 90/211 (42%), Gaps = 30/211 (14%) Query: 141 VPIV-LAASVEEQEETPSV---AIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSK 196 VPIV + S E P V A D + A L +KG AF P + Sbjct: 78 VPIVGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSG----- 132 Query: 197 KLQGYKRALEEANLPFNEQFVAEGDYT------YDSGLEALQHLMS-----LDKKP--TA 243 KR E F Q VAE Y ++ E QH + L P T Sbjct: 133 -----KRWATEREYAFR-QLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQTG 186 Query: 244 ILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLS-LMVRPQLSTVVQPTYDIGAVA 302 I++ TD A I+ + + +PE L +IG DN L+ + R LS+V Q +G A Sbjct: 187 IIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGYQA 246 Query: 303 MRLLTKLMNKEPVE-EHIVELPHRIELRKST 332 +LL +L++KE + + I+ P R+ R+ST Sbjct: 247 AKLLHRLLDKEEMPLQRILVPPVRVIERRST 277 >5OCP-A nrPDB Length = 302 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 111/230 (48%), Gaps = 20/230 (8%) Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 TTVG S + + + ++ A ++ +++ Q E ++ + + + + VD I Sbjct: 1 TTVGFSQVGSESGWRTSFSEAVKAEAKQRGIDLKFADAQQKQENQIKAVRSFIAQGVDAI 60 Query: 122 VFMGGNITDEH--VAEFKRSPVPIVLA-ASVEEQEET---PSVAIDYEQAIYDAVKLLVD 175 + T + E KR+ +P+V+ +++ +++ +A D+ + + L+D Sbjct: 61 IIAPVVETGWKPVLKEAKRAKIPVVIVDRNIKVDDDSLFLTRIASDFSEEGRKIGQWLMD 120 Query: 176 K--GHTDIAFVSGPMAE--PINRSKKLQGYKRALEEANLPFNEQFVAE--GDYTYDSGLE 229 K G+ DIA + G + I+R+ G+ + + AN P N + V G++T G E Sbjct: 121 KTQGNCDIAELQGTVGATAAIDRAA---GFNQVI--ANYP-NAKIVRSQTGEFTRAKGKE 174 Query: 230 ALQ-HLMSLDKKP-TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDN 277 ++ L + + +P A+ S DEMALG + A ++ GL +D+ I+ D Sbjct: 175 VMEGFLKAQNGQPLCAVWSHNDEMALGAVQAIKEAGLKPGKDILIVSVDG 224 >4XXH-A nrPDB Length = 255 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 15/188 (7%) Query: 110 LNTMLGKQVDGIVFMG-GNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYD 168 L + + +DG+V G IT+E +A ++ S +VL A + + SV D E AI Sbjct: 51 LGVLKRRNIDGVVLFGFTGITEEMLAHWQSS---LVLLA--RDAKGFASVCYDDEGAIKI 105 Query: 169 AVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGL 228 ++ L D+GH +I+++ P ++ ++ + Y + L A G Sbjct: 106 LMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKL---HPVAALPGLAMKQGY 162 Query: 229 EALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQL 288 E + +++ + TA+L ATD +ALG Q+Q + + L + NT L + P++ Sbjct: 163 ENVAKVIT--PETTALLCATDTLALGASKYLQEQRI---DTLQLASVGNTPLMKFLHPEI 217 Query: 289 STVVQPTY 296 T V P Y Sbjct: 218 VT-VDPGY 224 >1DBP-A nrPDB Length = 271 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 32/271 (11%) Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLN--TMLGKQVDG 120 T+ +++ +++ F+ L G + A YN+++ +S N KEL + T+ G ++ Sbjct: 3 TIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILL 62 Query: 121 IVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPS-----------VAIDY-EQAIYD 168 I + D V ++ +P++ + E S +A DY + + Sbjct: 63 INPTDSDAVDNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGE 122 Query: 169 AVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGL 228 K++ +G ++G A ++ +G+++A+ A FN D+ GL Sbjct: 123 GAKVIELQG------IAGTSAA----RERGEGFQQAV--AAHKFNVLASQPADFDRIKGL 170 Query: 229 EALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNT---RLSLMVR 285 +Q+L++ A+ + DEMALG + A Q G S D+ ++GFD T ++ Sbjct: 171 NVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKS---DVMVVGFDGTPDGEKAVNDG 227 Query: 286 PQLSTVVQPTYDIGAVAMRLLTKLMNKEPVE 316 +T+ Q IGA + K++ E V+ Sbjct: 228 KLAATIAQLPDQIGAKGVETADKVLKGEKVQ 258 >4ZJP-A nrPDB Length = 292 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 39/277 (14%) Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 T+ + + + + F+ L G + AT Y +++ +S + KEL + + V G Sbjct: 26 TIALTVSTLDNPFFVSLKDGAQKKATELGYKLVVLDSQNDPSKELSNVEDL---TVRGAK 82 Query: 123 FMGGNITDEH-----VAEFKRSPVPIV-LAASVEEQEETPSVAID-----------YEQA 165 + N TD VA R+ +P++ L + E +A D Q Sbjct: 83 VLLINPTDSAAVSNAVAIANRNKIPVITLDRGAAKGEVVSHIASDNVAGGKMAGDFIAQK 142 Query: 166 IYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYD 225 + D K++ +G +A ++ +G+K+A+E F+ D+ Sbjct: 143 LGDGAKVIQLEG----------LAGTSAARERGEGFKQAIEAHK--FDVLASQPADFDRT 190 Query: 226 SGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVR 285 GL ++L++ AI + DEMALG + A G + ++GFD T + Sbjct: 191 KGLNVTENLLASKGSVQAIFAQNDEMALGALRAISAAGKKVL----VVGFDGTEDGVKAV 246 Query: 286 PQ---LSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHI 319 +TV Q IG++ + K++ E V+ I Sbjct: 247 KSGKLAATVAQQPELIGSLGVETADKILKGEKVDAKI 283 >4WUT-A nrPDB Length = 313 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 64/278 (23%), Positives = 122/278 (43%), Gaps = 34/278 (12%) Query: 64 VGVIIPDISSIFYSELARGIED-IATMYKYNIILSN--SDQNMEKELHLLNTMLGKQVDG 120 + VI+ ++S F+ + +G + I + I ++ + +++++ + ++VD Sbjct: 26 IAVIVKTVNSTFWQNVQKGADAAIGKQKAHTITFQGPAAESAIADQVNMVENAVNRKVDA 85 Query: 121 IVFMGGNITDEHVAEFKRSP---VPIVLAASV----EEQEETPSVAIDYEQAIYDAVKLL 173 I+ + D V K++ +P+V+ S+ E+ +A D + A A K + Sbjct: 86 ILLAPSD-PDALVPAVKKAWEARIPVVIIDSMLSKDAEKYYQAFLATDNKAAGELAAKAM 144 Query: 174 VDKGHTD-----IAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDS-- 226 + K T+ +++V+G +E I R Y +A N + G Y S Sbjct: 145 IQKVGTEGKIAVMSYVAGAGSE-IGRVGGFTDYIKA--------NSKLQIVGPYYSQSQM 195 Query: 227 --GLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFD-NTRLSLM 283 L +++ + I A + A+G+ A + G + L IGFD N L Sbjct: 196 ATALNQTTDVLAANADLKGIFGANEPTAIGMGRAIKQAGKA--GKLVAIGFDGNQDLQEF 253 Query: 284 VRPQL--STVVQPTYDIGAVAMRLLTKLMNKEPVEEHI 319 V+ +TVVQ +Y +G + L KL++KE VE+ I Sbjct: 254 VKDGTLEATVVQGSYQMGEKGVDTLLKLLSKEKVEKFI 291 >3O75-A nrPDB Length = 272 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 61 TTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDG 120 T T+G I+PD+ + Y+ +A+ +E A Y +++++SD + E L ++ D Sbjct: 2 TRTLGFILPDLENPSYARIAKQLEQGARARGYQLLIASSDDQPDSERQLQQLFRARRCDA 61 Query: 121 IVFMGGNI--TDEHVAEFKRSPVPIV 144 + F+ + D+ E + +P++ Sbjct: 62 L-FVASCLPPEDDSYRELQDKGLPVI 86 >1UXC-A nrPDB Length = 65 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 8 DVAREANVSMATVSRVVNGNPN---VKPTTRKKVLEAIERLGYRPNAVARGL 56 ++AR A VS T S V+NG V T +KV+ + Y PNAVA GL Sbjct: 5 EIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHNYHPNAVAAGL 56 >2L8N-A nrPDB Length = 67 Score = 35.4 bits (80), Expect = 0.030, Method: Compositional matrix adjust. Identities = 21/52 (40%), Positives = 29/52 (55%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGL 56 T+ DVA +A VS ATVSR + V TR +V +A +GY P + R + Sbjct: 11 TMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNV 62 >4P2B-A nrPDB Length = 576 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 3/38 (7%) Query: 159 AIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSK 196 A DY Q +YD +LL+ KG +AFV E I R + Sbjct: 113 ASDYFQQLYDWAELLIKKG---LAFVDDDSLEEIRRKR 147 >3IGH-X nrPDB Length = 486 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 29/184 (15%) Query: 108 HLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQE--ETPSV----AID 161 HL LG ++ + G +E + KR I+ ++ E E P+ AID Sbjct: 67 HLHLDELGMSLEMVDLRGAKSIEELIQRLKRGKGRIIFGFGWDQDELGEWPTRKELNAID 126 Query: 162 YEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINR--SKKLQG-----YKRALEEANLPFNE 214 IY + +A + M E +N SK +++LEEA NE Sbjct: 127 KPVFIY--------RKCFHVAVANDKMLELLNLTPSKDFDEDTGIIKEKSLEEARKVINE 178 Query: 215 QFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSI-------P 267 + + DY Y A +HL+ L K + +S ++ + + ++ LSI P Sbjct: 179 RVLTVEDYVYYIK-RAQEHLLDLGVKSVSFMSVNEKALRALFYLEREGKLSINVFAYVTP 237 Query: 268 EDLD 271 E LD Sbjct: 238 EVLD 241 >3T4E-A nrPDB Length = 312 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 25/49 (51%) Query: 186 GPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHL 234 G MA PI S + +ALE+A LP+ + T+ S +E L+ L Sbjct: 35 GLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKAL 83 >4WZZ-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 9/106 (8%) Query: 164 QAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLP-FNEQFVAEGDY 222 QA+ DA+ L + G D A +S + N++ + G K ++++ N V GD Sbjct: 165 QALMDAI-LDISGGSGDWAVLS-AASTATNQNAWIDGMKTVMQDSKYSKLNLIGVYYGDD 222 Query: 223 TYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAA---QDQGLS 265 Y + + + +++ D I + T +GI+ AA QD+GLS Sbjct: 223 EYQASCDQTEAILAADPNIKVICAPT---TVGIMAAAKVLQDKGLS 265 >5EY9-A nrPDB Length = 629 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 12 EANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAV--ARGLA 57 E + ++ V ++NG+ V P + +K +A E G R AV + GLA Sbjct: 298 EPPLDLSNVKGILNGSEPVSPASMRKFFKAFEPYGLRETAVKPSYGLA 345 >3MMT-A nrPDB Length = 347 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 7/50 (14%) Query: 89 MYKYNIILSNSDQNM-------EKELHLLNTMLGKQVDGIVFMGGNITDE 131 + K N+++ D + EK +H+L + V GI F+ G TDE Sbjct: 225 ILKPNMVIDGKDARIASVEEVAEKTVHVLKQTVPAAVPGIAFLSGGQTDE 274 >1UQW-A nrPDB Length = 509 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 25/58 (43%) Query: 15 VSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDIS 72 S + + R ++ N KP KV EA+ RP V A T GV+ P I+ Sbjct: 259 ASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIA 316 >4DU5-A nrPDB Length = 336 Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPT---TRKKVLEAIERLGYRPNAVARGLASK 59 + T AR+ M R V+ +PN++PT T + + +AI L R + V G+ Sbjct: 166 SATTLPAARKTMDLMRAAGRSVSFDPNLRPTLWATPELMRDAINDLATRADWVLPGMEEG 225 Query: 60 KTTTVGVIIPDISSIFYSELA 80 + T G P+ + FY +L Sbjct: 226 RFLT-GETTPEGVARFYRQLG 245 >6AP1-H nrPDB Length = 330 Score = 27.3 bits (59), Expect = 9.2, Method: Compositional matrix adjust. Identities = 17/74 (22%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 79 LARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGG---NITDEHVAE 135 LA + D +K I + ++ +K LH++NT++ Q ++M ++ +E + + Sbjct: 48 LATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYNEKLKQ 107 Query: 136 FKRSPVPIVLAASV 149 K P ++L S+ Sbjct: 108 LKDGPWDVMLKRSL 121 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3OQN-A nrPDB 422 e-119 1RZR-D nrPDB 408 e-114 2O20-A nrPDB 354 3e-98 2PUG-A nrPDB 339 2e-93 3H5O-A nrPDB 319 1e-87 3CTP-A nrPDB 308 2e-84 5YSZ-A nrPDB 305 1e-83 3DBI-A nrPDB 299 1e-81 3KJX-A nrPDB 295 1e-80 3E3M-A nrPDB 295 1e-80 5UFH-A nrPDB 294 3e-80 3EDC-A nrPDB 287 4e-78 3JVD-A nrPDB 281 3e-76 3BIL-A nrPDB 278 2e-75 4O5A-A nrPDB 268 3e-72 6NDI-A nrPDB 256 1e-68 3H5T-A nrPDB 245 2e-65 3TB6-A nrPDB 236 8e-63 2IKS-A nrPDB 213 7e-56 3GYB-A nrPDB 197 5e-51 1DBP-A nrPDB 183 1e-46 4ZJP-A nrPDB 173 9e-44 4XXH-A nrPDB 151 4e-37 4FE4-A nrPDB 145 2e-35 5OCP-A nrPDB 142 2e-34 3O75-A nrPDB 141 4e-34 4WUT-A nrPDB 139 1e-33 1OSL-A nrPDB 88 4e-18 Sequences not found previously or not previously below threshold: 5DTE-A nrPDB 121 5e-28 2VK2-A nrPDB 111 6e-25 1GUD-A nrPDB 105 2e-23 4RS3-A nrPDB 103 1e-22 4RSM-A nrPDB 98 4e-21 3M9X-A nrPDB 89 3e-18 4YWH-A nrPDB 84 8e-17 4KZK-A nrPDB 64 6e-11 4YP9-A nrPDB 64 1e-10 2L8N-A nrPDB 59 3e-09 1UXC-A nrPDB 57 8e-09 2IPN-A nrPDB 57 8e-09 1GCG-A nrPDB 54 1e-07 4RXU-A nrPDB 45 5e-05 3R25-A nrPDB 35 0.057 2RAS-A nrPDB 34 0.11 4AWT-A nrPDB 34 0.14 4V6C-AB nrPDB 33 0.23 4TOI-A nrPDB 32 0.31 2BB3-A nrPDB 32 0.51 5JTL-E nrPDB 32 0.51 5NA1-A nrPDB 32 0.52 6BGD-A nrPDB 31 0.59 2REK-A nrPDB 31 0.68 5UI5-I nrPDB 31 0.91 5ZLU-EE nrPDB 30 1.1 2UXO-A nrPDB 30 1.1 1LFP-A nrPDB 30 1.2 3DAF-A nrPDB 30 1.3 5YDP-A nrPDB 29 2.4 2NP5-A nrPDB 29 2.4 5AWV-A nrPDB 29 2.7 3KTS-A nrPDB 29 2.8 3E70-C nrPDB 29 3.0 5D1W-A nrPDB 29 3.2 4MCX-A nrPDB 29 3.3 6CHV-A nrPDB 29 3.3 6CF1-A nrPDB 29 3.3 4MCT-A nrPDB 29 4.5 4I4I-A nrPDB 29 4.5 4PEV-A nrPDB 28 4.8 1X18-E nrPDB 28 5.1 2GP6-A nrPDB 28 6.0 2C4E-A nrPDB 28 6.0 5KS8-A nrPDB 28 6.2 2QWT-A nrPDB 28 7.1 4R28-A nrPDB 28 7.5 >3OQN-A nrPDB Length = 339 Score = 422 bits (1085), Expect = e-119, Method: Composition-based stats. Identities = 332/332 (100%), Positives = 332/332 (100%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT Sbjct: 2 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 61 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV Sbjct: 62 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 121 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA Sbjct: 122 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 181 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT Sbjct: 182 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 241 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA Sbjct: 242 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 301 Query: 303 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 334 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS Sbjct: 302 MRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 333 >1RZR-D nrPDB Length = 332 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 252/331 (76%), Positives = 292/331 (88%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 N+TIYDVAREA+VSMATVSRVVNGNPNVKP+TRKKVLE IERLGYRPNAVARGLASKKTT Sbjct: 2 NVTIYDVAREASVSMATVSRVVNGNPNVKPSTRKKVLETIERLGYRPNAVARGLASKKTT 61 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TVGVIIPDIS+IFY+ELARGIEDIATMYKYNIILSNSDQN +KELHLLN MLGKQVDGI+ Sbjct: 62 TVGVIIPDISNIFYAELARGIEDIATMYKYNIILSNSDQNQDKELHLLNNMLGKQVDGII 121 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 FM GN+T+EHV E K+SPVP+VLAAS+E + PSV IDYEQA +DAV+ L+D GH +IA Sbjct: 122 FMSGNVTEEHVEELKKSPVPVVLAASIESTNQIPSVTIDYEQAAFDAVQSLIDSGHKNIA 181 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 FVSG + EPIN +KK++GYKRAL E+ LP + ++ EGDYTYDSG+EA++ L+ D+KPT Sbjct: 182 FVSGTLEEPINHAKKVKGYKRALTESGLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPT 241 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 AI TDEMALG+IH AQD+GL++P DL+IIGFDNTRLS MVRPQL++VVQP YDIGAVA Sbjct: 242 AIFVGTDEMALGVIHGAQDRGLNVPNDLEIIGFDNTRLSTMVRPQLTSVVQPMYDIGAVA 301 Query: 303 MRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 MRLLTK MNKE V+ IV+LPHRIE R+STK Sbjct: 302 MRLLTKYMNKETVDSSIVQLPHRIEFRQSTK 332 >2O20-A nrPDB Length = 332 Score = 354 bits (908), Expect = 3e-98, Method: Composition-based stats. Identities = 167/332 (50%), Positives = 234/332 (70%), Gaps = 3/332 (0%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 S TIYDVAR A VSMATVSRVVNGN NVK TR+KVLEAI L YRPNAVARGLASK+T Sbjct: 4 STTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRT 63 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 TTVGVI+P I+S +++ + RG++DIA+MYKYN+IL+NSD ++EKE +L T L KQVDGI Sbjct: 64 TTVGVILPTITSTYFAAITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQVDGI 123 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 V+MG ++ ++ K S P+VL +++ +E PSV IDY A Y + K L+D G+ I Sbjct: 124 VYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTKKLIDSGNKKI 183 Query: 182 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 A++ G + + + ++++ GY+ AL EAN+ F+E V EG+Y+Y+ G + L+ Sbjct: 184 AYIMGSLKD-VENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLER--GA 240 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 T+ + + D +A+G++ A D+G+ +PED +II N+ ++ P L++V QP YD+GAV Sbjct: 241 TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAV 300 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 AMRLLTKLM KE VE++ + L H I R+STK Sbjct: 301 AMRLLTKLMLKEDVEQNQLVLDHEIFSRRSTK 332 >2PUG-A nrPDB Length = 340 Score = 339 bits (868), Expect = 2e-93, Method: Composition-based stats. Identities = 109/330 (33%), Positives = 181/330 (54%), Gaps = 5/330 (1%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 TI DVA+ ANVS TVS V+N V TR V AI+ L Y P+AVAR L T ++ Sbjct: 2 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 61 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 G++ + +++E+ +E Y +IL N+ N+EK+ L+ M K+VDG++ M Sbjct: 62 GLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVM 121 Query: 125 GGNITDEHVAEFKR-SPVPIVLAASVEEQEETPSVAIDYE-QAIYDAVKLLVDKGHTDIA 182 + +A + +P+V+ E + + ID + Y A + L+++GH +I Sbjct: 122 CSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIG 181 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 + GP+ E + +L G+ +A+EEA + E ++ +GD+ +SG A+Q ++S +PT Sbjct: 182 VIPGPL-EQNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPT 240 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 A+ D MA+G + AA + GL +P+D+ +IG+DN R + P L+T+ QP +G A Sbjct: 241 AVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETA 300 Query: 303 MR-LLTKLMNKEPVEEHIVELPHRIELRKS 331 LL +++NK + I P R+ R+S Sbjct: 301 FNMLLDRIVNKREEPQSIEVHP-RLIERRS 329 >3H5O-A nrPDB Length = 339 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 94/332 (28%), Positives = 167/332 (50%), Gaps = 4/332 (1%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 +T++DVA+ A VS TVSRV+N V R+KV++A++ L Y P+ A LAS K+ Sbjct: 4 GVTMHDVAKAAGVSAITVSRVLNQPQQVSEQLREKVMQAVDALAYVPSRSASTLASAKSR 63 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TV V+IP +++ + E GIE + Y +++ NS + +EL LL L + DG++ Sbjct: 64 TVLVLIPSLANTVFLETLTGIETVLDAAGYQMLIGNSHYDAGQELQLLRAYLQHRPDGVL 123 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 G + + + +P+V + + V E A + L+ +G I Sbjct: 124 ITGLSHAEPFERILSQHALPVVYMMDLADDGRC-CVGFSQEDAGAAITRHLLSRGKRRIG 182 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 F+ + E + K+L GY+ AL+ A+ +++ + G + L ++ Sbjct: 183 FLGAQLDERV--MKRLDGYRAALDAADCRDAGLEWLDPQPSSMQMGADMLDRALAERPDC 240 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 A+ D++A+G + +Q G+++PE L I GF++ + + P L+TV P DIG Sbjct: 241 DALFCCNDDLAIGALARSQQLGIAVPERLAIAGFNDLQPAAWCTPPLTTVATPRRDIGVH 300 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK 333 A + L +L++ E +L R+ LR+S++ Sbjct: 301 AAKALLQLIDGEEPASRRADLGFRLMLRRSSE 332 >3CTP-A nrPDB Length = 330 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 90/335 (26%), Positives = 167/335 (49%), Gaps = 16/335 (4%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 S I ++A+ A +S+ATVSR +N V R+K+ + ++ L Y PNA+AR + +K + Sbjct: 1 SLANIREIAKRAGISIATVSRHLNNTGYVSEDAREKIQKVVDELNYTPNALARAMFTKNS 60 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 T+G+++P+IS+ F++++A IE+ A Y + L N+D + EKE L + +V GI Sbjct: 61 KTIGLMVPNISNPFFNQMASVIEEYAKNKGYTLFLCNTDDDKEKEKTYLEVLQSHRVAGI 120 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 + D E+ +P+V A + +++ D A L +KG I Sbjct: 121 IASRSQCED----EYANIDIPVV-AFENHILDNIITISSDNYNGGRMAFDHLYEKGCRKI 175 Query: 182 AFVSGP---MAEPINRSKKLQGYK-RALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSL 237 + GP A + L G + + LE + F F + + + +++ +++ Sbjct: 176 LHIKGPEVFEATELRYKGFLDGARAKDLEIDFIEFQHDFQVK---MLEEDINSMKDIVNY 232 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 I D A ++ A + +G+SIP+++ IIGFDN+ + ++ P L+T+ QP Sbjct: 233 ----DGIFVFNDIAAATVMRALKKRGVSIPQEVQIIGFDNSFIGELLYPSLTTINQPIEA 288 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 + + LL K++N E V + ++ R++T Sbjct: 289 LAYTIIELLIKIINGEGVLIEDYIMEVKLIERETT 323 >5YSZ-A nrPDB Length = 360 Score = 305 bits (782), Expect = 1e-83, Method: Composition-based stats. Identities = 100/334 (29%), Positives = 172/334 (51%), Gaps = 9/334 (2%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 T+ VA A V TVSRV+NG+ V P TR+ V AI+ LGY PN AR L +++T TV Sbjct: 28 TLEMVAALAGVGRGTVSRVINGSDQVSPATREAVKRAIKELGYVPNRAARTLVTRRTDTV 87 Query: 65 GVIIPD-----ISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVD 119 +++ + + FY+ + G+ + + +L+ +E E L + G+ VD Sbjct: 88 ALVVSENNQKLFAEPFYAGIVLGVGVALSERGFQFVLATGRSGIEHE-RLGGYLAGQHVD 146 Query: 120 GIVFMGGNITDEHVAEFKRSPVPIVLAASVE--EQEETPSVAIDYEQAIYDAVKLLVDKG 177 G++ + + D + VP V +E+ V ID A + L++ G Sbjct: 147 GVLLLSLHRDDPLPQMLDEAGVPYVYGGRPLGVPEEQVSYVDIDNIGGGRQATQRLIETG 206 Query: 178 HTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSL 237 H IA ++GP + + ++LQGY+ AL A + ++E V+ GD+TYDSG+ A++ L+ Sbjct: 207 HRRIATIAGPQ-DMVAGVERLQGYREALLAAGMEYDETLVSYGDFTYDSGVAAMRELLDR 265 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 A+ +A+D M L + + G +PED+ ++G+D++ ++ P +++V QPT Sbjct: 266 APDVDAVFAASDLMGLAALRVLRASGRRVPEDVAVVGYDDSTVAEHAEPPMTSVNQPTEL 325 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKS 331 +G RLL + E E + L + +R+S Sbjct: 326 MGREMARLLVDRITGETTEPVRLVLETHLMVRES 359 >3DBI-A nrPDB Length = 338 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 100/334 (29%), Positives = 183/334 (54%), Gaps = 5/334 (1%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 MS T+ +VA+ A VS ATVSRV++GN V T+ +V +A+E GYRPN +AR L++K Sbjct: 1 MSLTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESGYRPNLLARNLSAKS 60 Query: 61 TTTVGVIIPD--ISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQV 118 T T+G+++ + I++SEL +A ++L++ + E+E + +L + Sbjct: 61 TQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHSAEEERQAIQYLLDLRC 120 Query: 119 DGIVFMGGNIT-DEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKG 177 D I+ ++ DE PI++ + + SV D++Q ++AV L++ G Sbjct: 121 DAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVWCDHKQTSFNAVAELINAG 180 Query: 178 HTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSL 237 H +IAF++G M P + ++L GYK AL + + NE+ +A G +T SG E ++ L+ Sbjct: 181 HQEIAFLTGSMDSPTS-IERLAGYKDALAQHGIALNEKLIANGKWTPASGAEGVEMLLER 239 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 K +A++++ D+MA+G + A ++G+++PE + +IGFD+ ++ P LS+V P + Sbjct: 240 GAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFDDIAIAPYTVPALSSVKIPVTE 299 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKS 331 + + L +++ ++ R S Sbjct: 300 MIQEIIGRLIFMLDGGDFSPPKTF-SGKLIRRDS 332 >3KJX-A nrPDB Length = 344 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 82/329 (24%), Positives = 149/329 (45%), Gaps = 5/329 (1%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 +T+ DV+ + VS TVSRV+ +V TR +VL A + LGY PN +A LAS + Sbjct: 9 RPLTLRDVSEASGVSEMTVSRVLRNRGDVSDATRARVLAAAKELGYVPNKIAGALASNRV 68 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 V VIIP +S++ + E+ GI + + ++ +D EKE +L ML + G+ Sbjct: 69 NLVAVIIPSLSNMVFPEVLTGINQVLEDTELQPVVGVTDYLPEKEEKVLYEMLSWRPSGV 128 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 + G ++ A + +P+V + + V I + +A + + ++ G+ I Sbjct: 129 IIAGLEHSEAARAMLDAAGIPVVEIMDSDGKPVDAMVGISHRRAGREMAQAILKAGYRRI 188 Query: 182 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 F+ M K+ +G+ L + + ++ G G E Q ++ Sbjct: 189 GFMGTKMPLDYRARKRFEGFTEVLGKNGVEIEDREFYSGGSALAKGREMTQAMLERSPDL 248 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 + + D +A G + +QG+ IP + + GF+N L + +L+T+ +IG Sbjct: 249 DFLYYSNDMIAAGGLLYLLEQGIDIPGQIGLAGFNNVELLQGLPRKLATMDACRLEIGRK 308 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRK 330 A ++ K + E+ E+ RI L Sbjct: 309 AAEIIAKRL-----EDPEAEIETRITLEP 332 >3E3M-A nrPDB Length = 355 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 87/338 (25%), Positives = 170/338 (50%), Gaps = 6/338 (1%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 +T+ DVA+ A VS TVSR + + + TR+++L+ ++ + Y P+ VA L +K++ Sbjct: 11 RPVTMRDVAKAAGVSRMTVSRALKKDSPISSETRERILKVVKDMNYVPDQVAGSLTTKRS 70 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 VG+++P ++++ +++ A+ + D+ ++L + + E+E L+ TML ++ + + Sbjct: 71 GFVGLLLPSLNNLHFAQTAQSLTDVLEQGGLQLLLGYTAYSPEREEQLVETMLRRRPEAM 130 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 V T++ + +R+ +PIV +V E+A YD L+ +G I Sbjct: 131 VLSYDGHTEQTIRLLQRASIPIVEIWEKPAHPIGHTVGFSNERAAYDMTNALLARGFRKI 190 Query: 182 AFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSLDKK 240 F+ + + + G+KRA+ EA L P E + + + G+ A + ++ Sbjct: 191 VFLGEKDDDWTRGAARRAGFKRAMREAGLNPDQEIRLGAPPLSIEDGVAAAELILQEYPD 250 Query: 241 PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTV-VQPT---Y 296 I +D A G++ + G+++PE + ++GF N +S P++STV V P Sbjct: 251 TDCIFCVSDMPAFGLLSRLKSIGVAVPEQVSVVGFGNFEVSRFASPEISTVRVDPIAIGR 310 Query: 297 DIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 334 + G++ +RLL +HI LP +E R S K+ Sbjct: 311 ETGSLILRLLDPKQRSPQTAQHIT-LPPVLEFRPSLKN 347 >5UFH-A nrPDB Length = 347 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 96/341 (28%), Positives = 155/341 (45%), Gaps = 11/341 (3%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 +TI DVA EA VS TVS V+NG +++ +TR +VLEA+++L Y N AR L + T Sbjct: 6 KGVTIKDVAAEAGVSFKTVSNVINGTGSMRESTRGRVLEAMDKLNYTINLSARSLKTGTT 65 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 +G+ I D S F S LA I A + Y +I++ QN + DG Sbjct: 66 GLLGLAIFDFSQPFASYLADQIIVCAREHHYGVIINTYGQNEHGLARAMRQANNLAADGW 125 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 + + +H +S P+VL + + V + +A+ L+D G+ I Sbjct: 126 IVFADHAMGQHSKMLDQS-YPLVLTGDWDAYGKVDQVTMPNVEAMRYTTNRLLDSGYRSI 184 Query: 182 AFVS--GPMAEPINRSK-------KLQGYKRALEEANLPFN-EQFVAEGDYTYDSGLEAL 231 A G + R ++QGY +A EE + + + G T DSG+ A Sbjct: 185 ALFGADGSLGARHYRQATEGTQELRVQGYMQAYEEHGIEARMDMLFSGGLLTSDSGVRAT 244 Query: 232 QHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTV 291 +M +P AI+ D MALG +H Q +G+ +P+D+ ++GFDN + P L+T+ Sbjct: 245 NLMMDQGVRPDAIICLNDAMALGALHQLQVRGIRVPDDVQVVGFDNVPEATYANPSLTTI 304 Query: 292 VQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 A+ +L + + + + + R ST Sbjct: 305 DPHIDSYARHAVDMLIERIQGYDGAKRVYTSDFTLVERSST 345 >3EDC-A nrPDB Length = 360 Score = 287 bits (735), Expect = 4e-78, Method: Composition-based stats. Identities = 100/335 (29%), Positives = 174/335 (51%), Gaps = 9/335 (2%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 M +T+YDVA A VS TVSRVVN +V TR+KV A+ L Y PN VA+ LA K+ Sbjct: 1 MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQ 60 Query: 61 TTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQN-MEKELHLLNTMLGKQVD 119 + +GV ++ S++ I+ A ++++S +++ +E ++ +L ++V Sbjct: 61 SLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVS 120 Query: 120 GIVF-MGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 G++ + D E + VP L V +Q S+ +E V+ LV GH Sbjct: 121 GLIINYPLDDQDAIAVEAACTNVP-ALFLDVSDQTPINSIIFSHEDGTRLGVEHLVALGH 179 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAEGDYTYDSGLEALQHLMSL 237 IA ++GP++ ++ +L G+ + L + P E+ EGD++ SG + +++ Sbjct: 180 QQIALLAGPLSS-VSARLRLAGWHKYLTRNQIQPIAER---EGDWSAMSGFQQTMQMLNE 235 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 PTA+L A D+MALG + A + GL + D+ ++G+D+T S P L+T+ Q Sbjct: 236 GIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRL 295 Query: 298 IGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 +G ++ L +L + V+ + + LP + RK+T Sbjct: 296 LGQTSVDRLLQLSQGQAVKGNQL-LPVSLVKRKTT 329 >3JVD-A nrPDB Length = 333 Score = 281 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 83/331 (25%), Positives = 157/331 (47%), Gaps = 12/331 (3%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 + ++ +VA A V AT SR ++G V P TR+KV A + L Y PN +A+ L ++ Sbjct: 5 AKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALREHRS 64 Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 VGVI+PD+S+ +YSE + I+ Y ++++ ++ +++ ++ +++ Q GI Sbjct: 65 ALVGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDV-VMESLISIQAAGI 123 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 181 + + V +P+V E P V D E + + ++ +I Sbjct: 124 IHVPV------VGSIAPEGIPMVQLTRGELGPGFPRVLCDDEAGFFQLTESVLGGSGMNI 177 Query: 182 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 241 A + G ++++G A A++ E G Y+ +SG E Q + + + P Sbjct: 178 AALVG-EESLSTTQERMRGISHA---ASIYGAEVTFHFGHYSVESGEEMAQVVFN-NGLP 232 Query: 242 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 301 A++ A+ + G++ A + +P D+ I G+D+ V ++T V P ++G Sbjct: 233 DALIVASPRLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKE 292 Query: 302 AMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 A+RLL L+ + V L ++ LR S+ Sbjct: 293 AVRLLVDLIENPELPTGDVVLQGQVILRGSS 323 >3BIL-A nrPDB Length = 348 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 92/328 (28%), Positives = 157/328 (47%), Gaps = 6/328 (1%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTV 64 T+ DVAR+A VS+AT SR + NP V +TR+++ + LGYR NA AR L S ++ T+ Sbjct: 10 TLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARALRSSRSNTI 69 Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 GVI+P + + +++ + I+ A+ I++NS+++ L + VDGI+ + Sbjct: 70 GVIVPSLINHYFAAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHGVDGIICV 129 Query: 125 GGNITDEHVAEFKRSPVPIVLAASVEEQEE-TPSVAIDYEQAIYDAVKLLVDKGHTDIAF 183 + + ++ +P+VL + P+ + + I AV+LL I + Sbjct: 130 PNEECANQLEDLQKQGMPVVLVDRELPGDSTIPTATSNPQPGIAAAVELLAHNNALPIGY 189 Query: 184 VSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTA 243 +SGPM ++L+ +K A AN EQ V G Y G E L+ K Sbjct: 190 LSGPMDTST-GRERLEDFKAAC--ANSKIGEQLVFLGGYEQSVGFEGATKLLDQGAKT-- 244 Query: 244 ILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAM 303 + + M +G+I A GL I +D+ +IGFD L + L+ + Q + A+ Sbjct: 245 LFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQRAV 304 Query: 304 RLLTKLMNKEPVEEHIVELPHRIELRKS 331 +LT+L+ +P + R+S Sbjct: 305 SILTELIAGTVPSVTKTTIPTALIHRES 332 >4O5A-A nrPDB Length = 345 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 94/337 (27%), Positives = 171/337 (50%), Gaps = 11/337 (3%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 + +TI+DVA+ + VS + VS +NG P V TR+KVL+ +LG+RPN A+ LA +T Sbjct: 9 AKVTIFDVAKASGVSSSAVSYALNGKPGVSDATREKVLQVARKLGWRPNGAAQSLAQSRT 68 Query: 62 TTVGVII---PDISS--IFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGK 116 +G+++ P + S + L G+ Y++++ S + ++ L + + Sbjct: 69 RRIGLVLGYDPQLLSAEPYIMRLISGLGSALEERDYSLLVRMSMDDDDEVSILEDWIATG 128 Query: 117 QVDGIVFMGGNITDEHVAEFKRSP-VPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVD 175 VD ++ + I D + K +P +P + A P++ D A ++ L Sbjct: 129 NVDALLLLNLEIGDPRIELMKNNPQMPCLALADSSLTSGLPTLMSDDAAASGTMIRHLAL 188 Query: 176 KGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLM 235 GH +IA V+GP + + + E + + DYT +SG EA + L+ Sbjct: 189 FGHKNIARVAGPEELGHSYI-RDAAFSEITTELGMRYR---CLHTDYTPESGAEATKRLL 244 Query: 236 SLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPT 295 S++ +PTAI+ D MAL A +G+ +PEDL II + ++ +++ P ++ + + Sbjct: 245 SVEPRPTAIIYDNDVMALAGESVASVKGVRVPEDLSIISWGDSFMNVAAHPPITALSRNI 304 Query: 296 YDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 + G +A +L+ KL++ E VE ++ E P+ + R ST Sbjct: 305 LESGRLAAQLMLKLIDGEDVE-NVEEPPYELIERAST 340 >6NDI-A nrPDB Length = 334 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 88/310 (28%), Positives = 153/310 (49%), Gaps = 11/310 (3%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 + ++ DVA+ ANVS+ TVSR +N +KP T +V AI Y P+ A+ + + Sbjct: 3 AMASLKDVAKLANVSLMTVSRALNTPERLKPETLARVQAAIAETNYVPDLSAKKIRGARA 62 Query: 62 T--TVGVI-IPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQV 118 T T+GV+ + +++ F E+ IE+ A + +N + N + ++ +++ +L + Sbjct: 63 TPSTIGVLALDTVTTPFSVEITLSIEETARAHGWNSFVVNMFSD-DRPEAVVDLLLSHRP 121 Query: 119 DGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 DGI+F + + E K +P VLA + S D EQ YDAVK L+ G+ Sbjct: 122 DGIIFTTMGLRQVPLPE-KLLTLPCVLANCESLSQPVASYIPDDEQGQYDAVKALLAAGY 180 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANLP---FNEQFVAEGDYTY-DSGLEALQHL 234 + P ++P ++ +G +RA EA + + ++ +GD Y D L H+ Sbjct: 181 RRPLCLHLPASQPATIRRR-RGLERACREAGIEPDHLSHSYMGQGDEHYHDIPAVVLAHI 239 Query: 235 MSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDN-TRLSLMVRPQLSTVVQ 293 +++ D +A + QGL IP+D+ ++G+DN + + P LSTV Sbjct: 240 REGKPGFDSVICGNDRIAFMVYQTLLGQGLRIPQDVAVVGYDNMVGIGDLFLPPLSTVQL 299 Query: 294 PTYDIGAVAM 303 P YDIG ++ Sbjct: 300 PHYDIGRLSA 309 >3H5T-A nrPDB Length = 366 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 81/343 (23%), Positives = 150/343 (43%), Gaps = 34/343 (9%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGY-RPNAVARGLASKKTTT 63 T+ +A + +S TVS N + R+++L+ E +GY P+ VAR L +++ Sbjct: 11 TLASIAAKLGISRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGA 70 Query: 64 VGVIIPDISSIFYSELAR-----GIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQV 118 +GV++ + + + ++A G+ A + +I ++ +++ + + V Sbjct: 71 IGVLLTEDLTYAFEDMASVDFLAGVAQAAGDTQLTLIPASPASSVDH-VSAQQLVNNAAV 129 Query: 119 DGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 DG+V D H+ + +P V+A +E P +A + +AI A + L+D GH Sbjct: 130 DGVVIYSVAKGDPHIDAIRARGLPAVIADQPAREEGMPFIAPNNRKAIAPAAQALIDAGH 189 Query: 179 TDIAFVSGPMAEPIN----------------RSKKLQGYKRALEEANL-----PFNEQFV 217 I +S + N + +++G EA + P E ++ Sbjct: 190 RKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVRGAMEVFIEAGIDPGTVPIMECWI 249 Query: 218 AEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDN 277 + E + L+ TA+L D +A G++ + G S P DL + GFD Sbjct: 250 NNRQHN----FEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSAPADLSLTGFDG 305 Query: 278 TRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV 320 T ++L L+TV+QP G A L K+++KE VE + Sbjct: 306 THMALAR--DLTTVIQPNKLKGFKAGETLLKMIDKEYVEPEVE 346 >3TB6-A nrPDB Length = 298 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 70/298 (23%), Positives = 143/298 (47%), Gaps = 14/298 (4%) Query: 46 GYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEK 105 G P A+ A T+GV+ IS + + RGIE + Y+++L++++ N + Sbjct: 1 GIDPFTSAKS-ALHSNKTIGVLTTYISDYIFPSIIRGIESYLSEQGYSMLLTSTNNNPDN 59 Query: 106 ELHLLNTMLGKQVDGIVFMGGNITDE-----HVAEFKRSPVPIVLAASVEEQEETPSVAI 160 E L +L + +DG++ + + +++ +P + + + PS + Sbjct: 60 ERRGLENLLSQHIDGLIVEPTKSALQTPNIGYYLNLEKNGIPFAMINASYAELAAPSFTL 119 Query: 161 DYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANL-PFNEQFVAE 219 D + A + L+ GHT + + A+ K++ G+ +A E L P + V Sbjct: 120 DDVKGGMMAAEHLLSLGHTHMMGIFK--ADDTQGVKRMNGFIQAHRERELFPSPDMIVTF 177 Query: 220 GDYTYDSGL-EALQHLMSLD--KKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFD 276 +S L E ++ + + PTAIL DE+AL +I ++ L +PED+ I+G+D Sbjct: 178 TTEEKESKLLEKVKATLEKNSKHMPTAILCYNDEIALKVIDMLREMDLKVPEDMSIVGYD 237 Query: 277 NTRLSLMVRPQLSTVVQPTYDIGAVAMR-LLTKLMNKEPVEEHIVELPHRIELRKSTK 333 ++ + + +L++V P +G A + ++ L +K+P +E ++ P + +R+S + Sbjct: 238 DSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDCLEHKKPKQEDVIFEP-ELIIRQSAR 294 >2IKS-A nrPDB Length = 293 Score = 213 bits (543), Expect = 7e-56, Method: Composition-based stats. Identities = 60/278 (21%), Positives = 122/278 (43%), Gaps = 8/278 (2%) Query: 44 RLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNM 103 Y PNAVA GL + +T ++G++IPD+ + Y+ +A +E A Y ++++ S+ Sbjct: 3 EHNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQP 62 Query: 104 EKELHLLNTMLGKQVDGIVFMGGNITD-EHVAEFKRSPVPIV-LAASVEEQEETPSVAID 161 + E+ + +L +QVD I+ + + P PIV L +++ + T V D Sbjct: 63 DNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVVGAD 122 Query: 162 YEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGD 221 + A A + + K + G + E + QG++ A ++ P F+ Sbjct: 123 QDDAEMLAEE--LRKFPAETVLYLGALPELSVSFLREQGFRTAWKDD--PREVHFLYANS 178 Query: 222 YTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGF-DNTRL 280 Y ++ + + + P A+ + + + G++ + +P DL I F DN L Sbjct: 179 YEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDNELL 238 Query: 281 SLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEH 318 + P L+ V Q D+ + ++ +++ + Sbjct: 239 DFLQCPVLA-VAQRHRDVAERVLEIVLASLDEPRKPKP 275 >3GYB-A nrPDB Length = 280 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 78/278 (28%), Positives = 128/278 (46%), Gaps = 15/278 (5%) Query: 58 SKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQ 117 S +T + V+I D S+ ++ +L + + D+ T Y + + +S + + + L + Sbjct: 2 SLRTQLIAVLIDDYSNPWFIDLIQSLSDVLTPKGYRLSVIDSLTSQAG-TDPITSALSMR 60 Query: 118 VDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEET-PSVAIDYEQAIYDAVKLLVDK 176 DGI+ +I D V + S P V+A + Q T SVA D + A K L+D Sbjct: 61 PDGIII-AQDIPDFTVPD---SLPPFVIAGTRITQASTHDSVANDDFRGAEIATKHLIDL 116 Query: 177 GHTDIAFVSGPMAEPINRSKKLQGYKRA--LEEANLPFNEQFVAEGDYTYDSGLEALQHL 234 GHT IA + + R + + RA LE + + V YT L Sbjct: 117 GHTHIAHLRVGSGAGLRRFESFEATMRAHGLEPLSNDYLGPAVEHAGYT------ETLAL 170 Query: 235 MSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQP 294 + + TAI S+ D A+G + AA++ GL +PEDL IIG+DNT L+ L+T+ Sbjct: 171 LKEHPEVTAIFSSNDITAIGALGAARELGLRVPEDLSIIGYDNTPLAQTRLINLTTIDDN 230 Query: 295 TYDIGAVAMRLLTKLMNKEPVEEHIV-ELPHRIELRKS 331 + +G A LL +++ E I+ L + R + Sbjct: 231 SIGVGYNAALLLLSMLDPEAPHPEIMHTLQPSLIERGT 268 >1DBP-A nrPDB Length = 271 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 57/265 (21%), Positives = 110/265 (41%), Gaps = 14/265 (5%) Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTM--LGKQVD 119 T+ +++ +++ F+ L G + A YN+++ +S N KEL + + G ++ Sbjct: 2 DTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKIL 61 Query: 120 GIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEET-PSVAIDYEQAIYDAVKLLVDKGH 178 I + D V ++ +P++ + E +A D A + K Sbjct: 62 LINPTDSDAVDNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAG 121 Query: 179 --TDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMS 236 + + G +A ++ +G+++A+ FN D+ GL +Q+L++ Sbjct: 122 EGAKVIELQG-IAGTSAARERGEGFQQAVAAH--KFNVLASQPADFDRIKGLNVMQNLLT 178 Query: 237 LDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMV---RPQLSTVVQ 293 A+ + DEMALG + A Q G S D+ ++GFD T +T+ Q Sbjct: 179 AHPDVQAVFAQNDEMALGALRALQTAGKS---DVMVVGFDGTPDGEKAVNDGKLAATIAQ 235 Query: 294 PTYDIGAVAMRLLTKLMNKEPVEEH 318 IGA + K++ E V+ Sbjct: 236 LPDQIGAKGVETADKVLKGEKVQAK 260 >4ZJP-A nrPDB Length = 292 Score = 173 bits (438), Expect = 9e-44, Method: Composition-based stats. Identities = 58/266 (21%), Positives = 106/266 (39%), Gaps = 17/266 (6%) Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTM--LGKQVDG 120 T+ + + + + F+ L G + AT Y +++ +S + KEL + + G +V Sbjct: 26 TIALTVSTLDNPFFVSLKDGAQKKATELGYKLVVLDSQNDPSKELSNVEDLTVRGAKVLL 85 Query: 121 IVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEET-PSVAIDYEQAIYDAVKLLVDK--- 176 I VA R+ +P++ + E +A D A + K Sbjct: 86 INPTDSAAVSNAVAIANRNKIPVITLDRGAAKGEVVSHIASDNVAGGKMAGDFIAQKLGD 145 Query: 177 GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMS 236 G I +A ++ +G+K+A+E F+ D+ GL ++L++ Sbjct: 146 GAKVIQLEG--LAGTSAARERGEGFKQAIEAH--KFDVLASQPADFDRTKGLNVTENLLA 201 Query: 237 LDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQ---LSTVVQ 293 AI + DEMALG + A G + ++GFD T + +TV Q Sbjct: 202 SKGSVQAIFAQNDEMALGALRAISAAGKKV----LVVGFDGTEDGVKAVKSGKLAATVAQ 257 Query: 294 PTYDIGAVAMRLLTKLMNKEPVEEHI 319 IG++ + K++ E V+ I Sbjct: 258 QPELIGSLGVETADKILKGEKVDAKI 283 >4XXH-A nrPDB Length = 255 Score = 151 bits (381), Expect = 4e-37, Method: Composition-based stats. Identities = 58/264 (21%), Positives = 111/264 (42%), Gaps = 14/264 (5%) Query: 60 KTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVD 119 V +I+ + S+ + + + Y+ I+ S + + L + + +D Sbjct: 1 SDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQFSPQLVAEHLGVLKRRNID 60 Query: 120 GIVFMG-GNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 G+V G IT+E +A ++ S +VL A + + SV D E AI ++ L D+GH Sbjct: 61 GVVLFGFTGITEEMLAHWQSS---LVLLAR--DAKGFASVCYDDEGAIKILMQRLYDQGH 115 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLD 238 +I+++ P ++ ++ + Y + L A G E + +++ Sbjct: 116 RNISYLGVPHSDVTTGKRRHEAYLAFCKAHKL---HPVAALPGLAMKQGYENVAKVIT-- 170 Query: 239 KKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDI 298 + TA+L ATD +ALG Q+Q + + L + NT L + P++ TV + Sbjct: 171 PETTALLCATDTLALGASKYLQEQRI---DTLQLASVGNTPLMKFLHPEIVTVDPGYAEA 227 Query: 299 GAVAMRLLTKLMNKEPVEEHIVEL 322 G A L + + I+ Sbjct: 228 GRQAACQLIAQVTGRSEPQQIIIP 251 >4FE4-A nrPDB Length = 392 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 58/276 (21%), Positives = 112/276 (40%), Gaps = 18/276 (6%) Query: 67 IIPDISSIFYSELARGIEDI--ATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFM 124 ++ + + + ++ G+ + A+ +++I + E ++ + DG++ Sbjct: 10 LLFNANKAYDRQVVEGVGEYLQASQSEWDIFI------EEDFRARIDKIKDWLGDGVI-- 61 Query: 125 GGNITDEHVAEFKRSPVPIV-LAASVEEQEETPSV---AIDYEQAIYDAVKLLVDKGHTD 180 + VPIV + S E P V A D + A L +KG Sbjct: 62 ADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNR 121 Query: 181 IAFVSGPMAEPIN-RSKKLQGYKRALEEANLPFNE-QFVAEGDYTYDSGLEALQHLMSLD 238 AF P + +++ +++ + E Q + + L + Sbjct: 122 FAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTL 181 Query: 239 KKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMV-RPQLSTVVQPTYD 297 T I++ TD A I+ + + +PE L +IG DN L+ + R LS+V Q Sbjct: 182 PPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQ 241 Query: 298 IGAVAMRLLTKLMNKEPVE-EHIVELPHRIELRKST 332 +G A +LL +L++KE + + I+ P R+ R+ST Sbjct: 242 MGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRST 277 >5OCP-A nrPDB Length = 302 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 56/285 (19%), Positives = 118/285 (41%), Gaps = 18/285 (6%) Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 121 TTVG S + + + ++ A ++ +++ Q E ++ + + + + VD I Sbjct: 1 TTVGFSQVGSESGWRTSFSEAVKAEAKQRGIDLKFADAQQKQENQIKAVRSFIAQGVDAI 60 Query: 122 VFMGGNITD--EHVAEFKRSPVPIVLAASV----EEQEETPSVAIDYEQAIYDAVKLLVD 175 + T + E KR+ +P+V+ ++ +A D+ + + L+D Sbjct: 61 IIAPVVETGWKPVLKEAKRAKIPVVIVDRNIKVDDDSLFLTRIASDFSEEGRKIGQWLMD 120 Query: 176 K--GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQF-VAEGDYTYDSGLEALQ 232 K G+ DIA + G + + G+ + + AN P + G++T G E ++ Sbjct: 121 KTQGNCDIAELQGTVGA-TAAIDRAAGFNQVI--ANYPNAKIVRSQTGEFTRAKGKEVME 177 Query: 233 -HLMSLDKKP-TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMV---RPQ 287 L + + +P A+ S DEMALG + A ++ GL +D+ I+ D Sbjct: 178 GFLKAQNGQPLCAVWSHNDEMALGAVQAIKEAGLKPGKDILIVSVDGVPDYFKAMADGDV 237 Query: 288 LSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKST 332 +TV Y +G A + + + ++ + +++ Sbjct: 238 NATVELSPY-LGGPAFDAIDAYLKGNKDQAKLISTTGDVFTQETA 281 >3O75-A nrPDB Length = 272 Score = 141 bits (356), Expect = 4e-34, Method: Composition-based stats. Identities = 44/238 (18%), Positives = 93/238 (39%), Gaps = 6/238 (2%) Query: 60 KTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVD 119 T T+G I+PD+ + Y+ +A+ +E A Y +++++SD + E L ++ D Sbjct: 1 HTRTLGFILPDLENPSYARIAKQLEQGARARGYQLLIASSDDQPDSERQLQQLFRARRCD 60 Query: 120 GI-VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGH 178 + V D+ E + +P++ + SV D A L+ Sbjct: 61 ALFVASCLPPEDDSYRELQDKGLPVIAIDRRLDPAHFCSVISDDRDASRQLAASLLSSAP 120 Query: 179 TDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLM-SL 237 IA + G E + G+ AL+ + ++ + G +Q L+ L Sbjct: 121 RSIALI-GARPELSVSQARAGGFDEALQ--GYTGEVRRYQGEAFSRECGQRLMQQLIDDL 177 Query: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPT 295 P A+++ + + G+ Q + + L + F + +L + ++ + Q Sbjct: 178 GGLPDALVTTSYVLLQGVFDTLQARPVD-SRQLQLGTFGDNQLLDFLPLPVNAMAQQH 234 >4WUT-A nrPDB Length = 313 Score = 139 bits (351), Expect = 1e-33, Method: Composition-based stats. Identities = 65/287 (22%), Positives = 124/287 (43%), Gaps = 34/287 (11%) Query: 55 GLASKKTTTVGVIIPDISSIFYSELARGIED-IATMYKYNIILSN--SDQNMEKELHLLN 111 L + + VI+ ++S F+ + +G + I + I ++ + +++++ Sbjct: 17 NLYFQSMGEIAVIVKTVNSTFWQNVQKGADAAIGKQKAHTITFQGPAAESAIADQVNMVE 76 Query: 112 TMLGKQVDGIVFMGGNITDEHVAEFKRSP---VPIVLAASV----EEQEETPSVAIDYEQ 164 + ++VD I+ + D V K++ +P+V+ S+ E+ +A D + Sbjct: 77 NAVNRKVDAILLAPSD-PDALVPAVKKAWEARIPVVIIDSMLSKDAEKYYQAFLATDNKA 135 Query: 165 AIYDAVKLLVDKGHTD-----IAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAE 219 A A K ++ K T+ +++V+G +E I R Y +A N + Sbjct: 136 AGELAAKAMIQKVGTEGKIAVMSYVAGAGSE-IGRVGGFTDYIKA--------NSKLQIV 186 Query: 220 GDYTYDS----GLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGF 275 G Y S L +++ + I A + A+G+ A + G + L IGF Sbjct: 187 GPYYSQSQMATALNQTTDVLAANADLKGIFGANEPTAIGMGRAIKQAGKA--GKLVAIGF 244 Query: 276 D-NTRLSLMVRPQL--STVVQPTYDIGAVAMRLLTKLMNKEPVEEHI 319 D N L V+ +TVVQ +Y +G + L KL++KE VE+ I Sbjct: 245 DGNQDLQEFVKDGTLEATVVQGSYQMGEKGVDTLLKLLSKEKVEKFI 291 >5DTE-A nrPDB Length = 311 Score = 121 bits (303), Expect = 5e-28, Method: Composition-based stats. Identities = 46/283 (16%), Positives = 114/283 (40%), Gaps = 18/283 (6%) Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIIL--SNSDQNMEKELHLLNTMLGKQVDGI 121 + +++ +S+ ++ + +G E+ A ++I+ + + + E+ + L+ M+ K+VD I Sbjct: 29 IALLMKTLSNEYFISMRQGAEETAKQKDIDLIVQVAEKEDSTEQLVGLVENMIAKKVDAI 88 Query: 122 VFMGGNITD--EHVAEFKRSPVPIVLAA-------SVEEQEETPSVAIDYEQAIYDAVKL 172 + + + +++ +PI+ + + V +D Y K Sbjct: 89 IVTPNDSIAFIPAFQKAEKAGIPIIDLDVRLDAKAAEAAGLKFNYVGVDNFNGGYLEAKN 148 Query: 173 LVDK-GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEAL 231 L + G + + N ++ G +A E ++ + L Sbjct: 149 LAEAIGKKGNVAILEGIPGVDNGEQRKGGALKAFAEYP-DIKIVASQSANWETEQALNVT 207 Query: 232 QHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLS---LMVRPQL 288 ++++ + I +A D MA+G + A ++ GL+ + + G+D L+ + Sbjct: 208 TNILTANPNINGIFAANDNMAIGAVTAVENAGLA--GKVLVSGYDGIPLAIEYVKQGKMQ 265 Query: 289 STVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKS 331 +T+ Q A+A+ K +NK+ + P ++ +S Sbjct: 266 NTIDQLPKKQVAIAIEHALKQINKQEIPSVYYVDPVVVDKEQS 308 >2VK2-A nrPDB Length = 306 Score = 111 bits (276), Expect = 6e-25, Method: Composition-based stats. Identities = 38/230 (16%), Positives = 83/230 (36%), Gaps = 14/230 (6%) Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 TVG S + + + A + +++ Q E ++ + + + + VD I Sbjct: 4 TVGFSQVGSESGWRAAETNVAKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIF 63 Query: 123 FMGGNIT--DEHVAEFKRSPVPIVLAASV----EEQEETPSVAIDYEQAIYDAVKLLVDK 176 T + + E K + +P+ L ++ +V D LV + Sbjct: 64 IAPVVATGWEPVLKEAKDAEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKE 123 Query: 177 GH---TDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQ- 232 + ++ + G + + + +G+ A++ A GD+T G E ++ Sbjct: 124 VNGKPCNVVELQGTVGASV-AIDRKKGFAEAIKNAPN-IKIIRSQSGDFTRSKGKEVMES 181 Query: 233 --HLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRL 280 + K + + D+M +G I A ++ GL +D+ D Sbjct: 182 FIKAENNGKNICMVYAHNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPD 231 >1GUD-A nrPDB Length = 288 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 50/281 (17%), Positives = 103/281 (36%), Gaps = 22/281 (7%) Query: 65 GVIIPDISSIFYSELARGIEDIATMYKYNI--ILSNSDQNMEKELHLLNTMLGKQVDGIV 122 V++ +S+ F+ ++ +GIED A ++ S S+ + + +L L + K GI Sbjct: 5 AVVLKTLSNPFWVDMKKGIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIA 64 Query: 123 FMGG---NITDEHVAEFKRSPVPIVLAASVE-------EQEETPSVAIDYEQAIYDAVKL 172 F N+ +K+ + L ++ V D Sbjct: 65 FAPLSSVNLVMPVARAWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASF 124 Query: 173 LVDKGHTD---IAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLE 229 ++DK + +A + G +++ G A ++A+ D+ L+ Sbjct: 125 IIDKLGAEGGEVAIIEGKAGNASGEARR-NGATEAFKKAS-QIKLVASQPADWDRIKALD 182 Query: 230 ALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQ-- 287 +++ + AI A D MA+G+ A + G + + ++G D + + Sbjct: 183 VATNVLQRNPNIKAIYCANDTMAMGVAQAVANAGKT--GKVLVVGTDGIPEARKMVEAGQ 240 Query: 288 -LSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIE 327 +TV Q DIGA ++L+ V ++ Sbjct: 241 MTATVAQNPADIGATGLKLMVDAEKSGKVIPLDKAPEFKLV 281 >4RS3-A nrPDB Length = 327 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 51/283 (18%), Positives = 118/283 (41%), Gaps = 19/283 (6%) Query: 57 ASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGK 116 A+ T +GV + D+SS F +E G++ A ++ ++++ ++ + +++++ + Sbjct: 8 ANSDTKRIGVTVYDMSS-FITEGKEGMDTYAKANNIELVWNSANNDVSTQASQVDSLINQ 66 Query: 117 QVDGIVFMGGNIT--DEHVAEFKRSPVPIVLAASVEEQEETP-SVAIDYEQAIYDAVKLL 173 VD I+ + VA K +P++ + E + +V D A ++++ Sbjct: 67 GVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALETPDLAGNVQPDDVAAGAQEMQMM 126 Query: 174 VDK--GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLP-FNEQFVAEGDYTYDSGLEA 230 D+ G +I + GP+ + +G + L A P ++ D + Sbjct: 127 ADRLGGKGNIVILQGPLG-GSGEINRGKGIDQVL--AKYPDIKVLAKDTANWKRDEAVNK 183 Query: 231 LQHLMSL-DKKPTAILSATDEMALGIIHAAQDQGLS-IPEDLDIIGFDNTRLSLMVRPQ- 287 +++ +S + +++ D+M LG + A ++ G + +P I+G D L Sbjct: 184 MKNWISSFGPQIDGVVAQNDDMGLGALQALKEAGRTGVP----IVGIDGIEDGLNAVKSG 239 Query: 288 --LSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIEL 328 + T +Q + + + L+ E V+ V + I Sbjct: 240 DFIGTSLQNGTVELSAGLAVADALVKGEDVKTDPVYVMPAITK 282 >4RSM-A nrPDB Length = 327 Score = 98.3 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 55/283 (19%), Positives = 122/283 (43%), Gaps = 19/283 (6%) Query: 57 ASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGK 116 A+ TT +GV + D+SS F + G++ A +I ++++ ++ + +++M+ + Sbjct: 8 ANSDTTRIGVTVYDMSS-FITAGKEGMDAYAKDNNIELIWNSANLDVSTQASQVDSMINQ 66 Query: 117 QVDGIVFMGGNIT--DEHVAEFKRSPVPIVLAASVEEQEETP-SVAIDYEQAIYDAVKLL 173 VD I+ + VA K +P+V + + ++ +V D A ++++ Sbjct: 67 GVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDSKDIAGNVQPDDVAAGAQEMQMM 126 Query: 174 VDK--GHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLP-FNEQFVAEGDYTYDSGLEA 230 D+ G +I + GP+ + + +G ++ L A P ++ D + Sbjct: 127 ADRLGGKGNIVILQGPLGQ-SGELDRSKGIEQVL--AKYPDIKVLAKDTANWKRDEAVNK 183 Query: 231 LQHLMSL-DKKPTAILSATDEMALGIIHAAQDQGLS-IPEDLDIIGFDNTRLSLMVRPQ- 287 +++ +S + +++ D+M LG + A ++ G + +P I+G D L Sbjct: 184 MKNWISGFGPQIDGVVAQNDDMGLGALQALKESGRTGVP----IVGIDGIEDGLNAVKSG 239 Query: 288 --LSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIEL 328 + T +Q A + + +L EPV + V + I Sbjct: 240 DFIGTSLQNGTVELAAGLAVANRLAKGEPVNKEPVYIMPAITK 282 >3M9X-A nrPDB Length = 313 Score = 89.0 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 47/265 (17%), Positives = 101/265 (38%), Gaps = 12/265 (4%) Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDG--I 121 +G+ I D+ + + A + + +++ N E ++ + M+ + VD I Sbjct: 5 IGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVI 64 Query: 122 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPS-VAIDYEQAIYDAVKLLVDKGHTD 180 + G + V E K+ + ++ + + ++ D E+ K LVD Sbjct: 65 IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQG 124 Query: 181 IAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEG---DYTYDSGLEALQHLMSL 237 F+ G N G + L+ + V + + ++ L+ +++ ++ Sbjct: 125 NYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTA 184 Query: 238 DK-KPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLS---TVVQ 293 + K A++++ D A G I A QGLS + I G D + + TV + Sbjct: 185 NNNKIDAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGTQTMTVYK 242 Query: 294 PTYDIGAVAMRLLTKLMNKEPVEEH 318 P + A + +L N + + Sbjct: 243 PITLLANTAAEIAVELGNGQEPKAD 267 >1OSL-A nrPDB Length = 62 Score = 88.3 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 30/61 (49%), Positives = 38/61 (62%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 M +T+YDVA A VS TVSRVVN +V TR+KV A+ L Y PN A+ LA K+ Sbjct: 1 MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRCAQQLAGKQ 60 Query: 61 T 61 + Sbjct: 61 S 61 >4YWH-A nrPDB Length = 332 Score = 84.0 bits (206), Expect = 8e-17, Method: Composition-based stats. Identities = 47/266 (17%), Positives = 108/266 (40%), Gaps = 12/266 (4%) Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 T+G+ I D+ + + A +++ +++ + ++ + ML K VD +V Sbjct: 27 TIGMSIDDLRLERWQKDRDIFVKKAESLGAKVLVQSANGDDSAQISQIENMLNKNVDVLV 86 Query: 123 FMG--GNITDEHVAEFKRSPVPIVLAASVEEQEETPS-VAIDYEQAIYDAVKLLVDKGHT 179 + G++ ++E K+ V ++ + + V+ D E+ ++ + Sbjct: 87 IIPHNGDVLSNVISEAKKEGVKVLAYDRLINNADLDFYVSFDNEKVGELQADAIIKEKPE 146 Query: 180 DIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEG---DYTYDSGLEALQHLMS 236 F+ G N +G + L+ + V + + + L+ +++ ++ Sbjct: 147 GNYFLMGGSPVDNNAKLFRKGQMKVLQPLIDSGKIKVVGDQWVDSWLAEKALQIMENALT 206 Query: 237 LDKK-PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLS---TVV 292 +K A++++ D A G I A QGLS + I G D ++ + + TV Sbjct: 207 ANKNNIDAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAAIKRIVEGTQTMTVY 264 Query: 293 QPTYDIGAVAMRLLTKLMNKEPVEEH 318 +P ++ A L L +E +E + Sbjct: 265 KPITNLADKAAELSVALGKEEKLEPN 290 >4KZK-A nrPDB Length = 337 Score = 64.4 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 30/294 (10%), Positives = 96/294 (32%), Gaps = 25/294 (8%) Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVF 123 +G ++ ++ + R E A + + + + + EK L+++ ++ G++ Sbjct: 39 IGFVVKQPDDPWFQDEWRFAEQAAKDKHFTL-VKIAAPSGEKVSTALDSLAAQKAQGVII 97 Query: 124 MGGN--ITDEHVAEFKRSPVPIVLAASVEEQE------ETPSVAIDYEQAIYDAVKLLVD 175 + + A+ KR + ++ + P + I + + Sbjct: 98 CAPDVKLGPGIAAKAKRYGMKLMSVDDQLVDGRGAPLADVPHMGISAYRIGRQVGDAIAA 157 Query: 176 KGHTD------IAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEG-DYTYDSGL 228 + + + + ++ G AL+ A A + Sbjct: 158 EAKRRGWNPAEVGVLRLAYDQLPTARERTTGAVDALKAAGFAAANVVDAPEMTADTEGAF 217 Query: 229 EALQHLMSLDKKPT--AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLS--LMV 284 A + + + D+ +G + A + +G+ +D+ +G + ++++ Sbjct: 218 NAANIAFTKHRNFRHWVAFGSNDDTTVGAVRAGEGRGIGT-DDMIAVGINGSQVALNEFA 276 Query: 285 RPQLS----TVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS 334 +P+ + +++ G + + + +V + R + K+ Sbjct: 277 KPKPTGFFGSILLNPRLHGYDTSVNMYDWITQNRTPPPLVLTSGTLITRANEKT 330 >4YP9-A nrPDB Length = 345 Score = 63.6 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 37/258 (14%), Positives = 84/258 (32%), Gaps = 19/258 (7%) Query: 75 FYSELARGIEDIATM----YKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITD 130 ++ E Y+ N + + + +++++ L L + D ++F Sbjct: 61 YWVRNIASFEKRLYKLNINYQLNQVFTRPNADIKQQSLSLMEALKSKSDYLIFTLDTTRH 120 Query: 131 EHVAE--FKRSPVPIVL------AASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIA 182 E + ++L ++ + V D+ + + Sbjct: 121 RKFVEHVLDSTNTKLILQNITTPVREWDKHQPFLYVGFDHAEGSRELATEFGKFFPKHTY 180 Query: 183 FVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPT 242 + +E + + + N F Q T SG +A + ++ Sbjct: 181 YSVLYFSEGYISDVRGDTFIHQVNRDNN-FELQSAYYTKATKQSGYDAAKASLAKHPDVD 239 Query: 243 AILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDN--TRLSLMVRPQL-STVVQPTYDIG 299 I + + ++ALG + A + G ED+ I G+ L + + L TV++ D G Sbjct: 240 FIYACSTDVALGAVDALAELGR---EDIMINGWGGGSAELDAIQKGDLDITVMRMNDDTG 296 Query: 300 AVAMRLLTKLMNKEPVEE 317 + + +PV Sbjct: 297 IAMAEAIKWDLEDKPVPT 314 >2L8N-A nrPDB Length = 67 Score = 58.6 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 21/57 (36%), Positives = 31/57 (54%) Query: 5 TIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 61 T+ DVA +A VS ATVSR + V TR +V +A +GY P + R + ++ Sbjct: 11 TMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNES 67 >1UXC-A nrPDB Length = 65 Score = 57.5 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 6 IYDVAREANVSMATVSRVVNGNP---NVKPTTRKKVLEAIERLGYRPNAVARGLA 57 + ++AR A VS T S V+NG V T +KV+ + Y PNAVA GL Sbjct: 3 LDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHNYHPNAVAAGLR 57 >2IPN-A nrPDB Length = 318 Score = 57.5 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 43/286 (15%), Positives = 94/286 (32%), Gaps = 36/286 (12%) Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMY-KYNIILSNSDQNMEKELHLLNTMLGKQV-- 118 T +GV I F S + + IE A +++++S + K+ ++ +L K V Sbjct: 4 TRIGVTIYKYDDCFMSVVRKAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKA 63 Query: 119 DGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPS------VAIDYEQAI----YD 168 I + + + + VP+V ++ S V D +++ Sbjct: 64 LAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDL 123 Query: 169 AVKL--------LVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEG 220 K L G + G P + + + L + + + + Sbjct: 124 IAKHWAANQGWDLNKDGQIQFVLLKGEPGHP-DAEARTTYVIKELNDKGIKTEQLQLDTA 182 Query: 221 DYTYDSGLEALQHLMSLDKKPTA-----ILSATDEMALGIIHAAQDQGLSIPEDLDIIGF 275 + + + +S P A +++ D MA+G + A + S + + G Sbjct: 183 MWDTAQAKDKMDAWLS---GPNANKIEVVIANNDCMAMGAVEALKAHNKS---SIPVFGV 236 Query: 276 DNTRLSLMVRPQLS---TVVQPTYDIGAVAMRLLTKLMNKEPVEEH 318 D +L + + TV+ + L L + + + Sbjct: 237 DALPEALALVKSGALAGTVLNDANNQAKATFDLAKNLADGKGAADG 282 >1GCG-A nrPDB Length = 309 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 38/252 (15%), Positives = 83/252 (32%), Gaps = 33/252 (13%) Query: 62 TTVGVIIPDISSIFYSELARGIEDIATMY-KYNIILSNSDQNMEKELHLLNTMLGKQV-- 118 T +GV I F S + + IE +++++S + K+ ++ +L K V Sbjct: 3 TRIGVTIYKYDDNFMSVVRKAIEKDGKSAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKA 62 Query: 119 DGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPS------VAIDYEQAI----YD 168 I + + + + VP+V ++ S V D +++ Sbjct: 63 LAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGVIQGDL 122 Query: 169 AVKL--------LVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEG 220 K L G + G P + + + L + + + + Sbjct: 123 IAKHWQANQGWDLNKDGKIQYVLLKGEPGHP-DAEARTTYVVKELNDKGIQTEQLALDTA 181 Query: 221 DYTYDSGLEALQHLMSLDKKPTA-----ILSATDEMALGIIHAAQDQGLSIPEDLDIIGF 275 + + + +S P A +++ D MA+G + A + S + + G Sbjct: 182 MWDTAQAKDKMDAWLS---GPNANKIEVVIANNDAMAMGAVEALKAHNKS---SIPVFGV 235 Query: 276 DNTRLSLMVRPQ 287 D +L + Sbjct: 236 DALPEALALVKS 247 >4RXU-A nrPDB Length = 367 Score = 44.7 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 50/150 (33%), Gaps = 6/150 (4%) Query: 64 VGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVF 123 VG+++P + + + Y + + S + KE + ++ K + ++ Sbjct: 33 VGIVLPTKDEPRWIQDETRFREALQQAGYQVEILFSQGSSAKEKENVEALIAKGIKVLII 92 Query: 124 MGGNIT--DEHVAEFKRSPVPIVLAASVEEQEETP--SVAIDYEQAIYDAVKLLVD--KG 177 + T + + V ++ + + + V D + LVD G Sbjct: 93 CPHDGTAAAAAAEAARAAGVKVISYDRLIRETDAVDYYVTFDSIAVGAQQAQYLVDHASG 152 Query: 178 HTDIAFVSGPMAEPINRSKKLQGYKRALEE 207 + ++ A N +G + L+ Sbjct: 153 TGNPLYLYAGAASDNNAFLFFEGAWKVLQP 182 >3R25-A nrPDB Length = 401 Score = 34.7 bits (78), Expect = 0.057, Method: Composition-based stats. Identities = 20/156 (12%), Positives = 54/156 (34%), Gaps = 15/156 (9%) Query: 60 KTTTVGVIIPDISS------IFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTM 113 + + V++ + + ++ + Y I++ + N+E ++ Sbjct: 20 RHNLITVVVETNEGVTGFGCATFQQRPLAVKTMVDEYLKPILIGKNANNIEDLWQMMMVN 79 Query: 114 LGKQVDGIVFMGGNITDEHVAEFKR--SPVPIVLAASVEEQEETP---SVAIDYEQAIYD 168 + ++ + D + + K + +P+ + ++ P D + IYD Sbjct: 80 AYWRNGPVINNAISGVDMALWDIKAKLAGMPLHQLFGGKSRDAIPVYTHATSDTMEGIYD 139 Query: 169 AVKLLVDKGHTDI----AFVSGPMAEPINRSKKLQG 200 V+ ++KG+ I F G + +G Sbjct: 140 LVEGFLEKGYKHIRCQLGFYGGVPTDLHTTQNPTEG 175 >2RAS-A nrPDB Length = 212 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 8/48 (16%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRP 49 + +T+ ++A A +S A +SR TR+ ++EAI + P Sbjct: 30 AGLTLSELAARAGISQANLSRYF--------ETREDLMEAIADYWFHP 69 >4AWT-A nrPDB Length = 365 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 40/254 (15%), Positives = 83/254 (32%), Gaps = 33/254 (12%) Query: 10 AREANVSMATVSRVVNGNPNVKPTTRKK------VLEAIERLGYRPNAVARGLASKKTTT 63 A+ +V T ++G + +T K V + G+ AV R + Sbjct: 99 AQLWHVGRVTHPDNIDGQQPISSSTLKAENVKVFVDNGSDEPGFVDVAVPRAMTKAD--- 155 Query: 64 VGVIIPDISSIFYSELA---RGIEDIATMYKY---NIILSNSDQNMEKELHLLNTMLGKQ 117 + +I D + + GIE A Y I S ++ ++ L L + Sbjct: 156 IAQVIADYRQAALNAMEAGFDGIELHA-ANGYLINQFIDSEANNRSDEYGGSLENRL-RF 213 Query: 118 VDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKG 177 +D +V + + + P+ + + + Y A L++K Sbjct: 214 LDEVVAALVDAIGAERVGVRLA--PLTTLNGTVDADPILT---------YTAAAALLNK- 261 Query: 178 HTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSL 237 I ++ + + +KRAL EA + + G Y + +A+ ++ Sbjct: 262 -HRIVYLHIAEVDWDDAPDTPVSFKRALREA---YQGVLIYAGRYNAEKAEQAINDGLAD 317 Query: 238 DKKPTAILSATDEM 251 A ++ Sbjct: 318 MIGFGRPFIANPDL 331 >4V6C-AB nrPDB Length = 241 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 7/57 (12%), Positives = 18/57 (31%), Gaps = 1/57 (1%) Query: 118 VDGIVFMGGNITDEHVAEFKRSPVPI-VLAASVEEQEETPSVAIDYEQAIYDAVKLL 173 D + + + + E +P+ + + + + V + AI L Sbjct: 158 PDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYL 214 >4TOI-A nrPDB Length = 326 Score = 32.4 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 7/57 (12%), Positives = 18/57 (31%), Gaps = 1/57 (1%) Query: 118 VDGIVFMGGNITDEHVAEFKRSPVPI-VLAASVEEQEETPSVAIDYEQAIYDAVKLL 173 D + + + + E +P+ + + + + V + AI L Sbjct: 161 PDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYL 217 >2BB3-A nrPDB Length = 221 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 190 EPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATD 249 E I R++ + G +RALE A + + + + G E + + ++ A++S D Sbjct: 42 EIIERAEVIYGSRRALELAGVVDDSRARILRSF---KGDEIRRIMEEGREREVAVISTGD 98 Query: 250 EMALGIIHAAQDQGLSIPEDLDI 272 M G+ ++ I ED++I Sbjct: 99 PMVAGLGRVLRE----IAEDVEI 117 >5JTL-E nrPDB Length = 471 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 41/292 (14%), Positives = 92/292 (31%), Gaps = 33/292 (11%) Query: 5 TIYDVAREANVSMATVS--------------RVVNGNPNVKPTTRKKVLEAIERLGYRPN 50 TI ++A+ A ++ VS V + T +K G + + Sbjct: 153 TILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGS 212 Query: 51 AVARGLASKKTTTVGVIIPDISSIFYSELARG--IEDIATMYKYNIILSNSDQNMEKELH 108 + L ++ T+G + + +G + + A Y ++ + N E + Sbjct: 213 ITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEAN 272 Query: 109 LLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAA-SVEEQEETPSVAIDYEQAIY 167 +LG DG M P V + + + P++A ++AI Sbjct: 273 QQKPLLGLFADG--NMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIE 330 Query: 168 DAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSG 227 K +KG V G + + + + + + + Sbjct: 331 LLSKN--EKGF--FLQVEGASIDKQDHAANP------CGQIGETVDLDEAVQRALEFAKK 380 Query: 228 LEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTR 279 +++ D + + A D A G+ A + ++ ++ + N+ Sbjct: 381 EGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAV----MVMSYGNSE 428 >5NA1-A nrPDB Length = 408 Score = 31.6 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 35/105 (33%), Gaps = 17/105 (16%) Query: 234 LMSLDKKPTAILSATDEMALGI---------IHAAQDQGLSIPEDLDIIGFDNTR----- 279 ++ +D + + + T A G+ + + +DL I G+DN Sbjct: 250 VVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFEGVKRGRIVTKQDLTINGYDNIFVIGDC 309 Query: 280 ---LSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVE 321 + L T Q G + + +++N E EE Sbjct: 310 SAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYV 354 >6BGD-A nrPDB Length = 378 Score = 31.3 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Query: 226 SGLEALQHLMSLDKK-PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMV 284 S E++ ++ ++S D MA+G + A+ + P L I G+D ++ Sbjct: 149 SATESMGSWVAKFADKIDLVISNNDGMAMGCLQAS-----NYPRGLPIFGYDANADAVES 203 Query: 285 --RPQLS-TVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV 320 + +L+ TV Q ++++ L++ E+ + Sbjct: 204 VGKGELTGTVSQNVDAQAVAVLQIIRNLLDGSSGEDVVA 242 >2REK-A nrPDB Length = 199 Score = 31.3 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Query: 2 SNITIYDVAREANVSMATVSRVV-NGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKK 60 ++ ++ ++AR A V AT+ R + ++ +++V + + AR LA++ Sbjct: 34 ADASLEEIARRAGVGSATLHRHFPSRWGLLQAVFQERVAQLCDE--------ARSLAAEH 85 Query: 61 TTTVGVIIPDISSIFYSELARGIEDIA 87 + S + + RG Sbjct: 86 PPATALTRWLTSLAVFGAVTRGAARSL 112 >5UI5-I nrPDB Length = 342 Score = 30.9 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 17/27 (62%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGN 27 + +T+ +V+ E + +T+SR+VN Sbjct: 233 LKPLTLREVSSEIGIHESTLSRIVNSK 259 >5ZLU-EE nrPDB Length = 497 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 18/44 (40%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIER 44 + I I V A +S VS V N + TR K+ A + Sbjct: 73 LGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQ 116 >2UXO-A nrPDB Length = 210 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 21/55 (38%), Gaps = 7/55 (12%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARG 55 ++ T+ D+A A V+ + N + V ++ L + +AR Sbjct: 29 VARTTLADIAELAGVTRGAIYWHFNNKAEL-------VQALLDSLHETHDHLARA 76 >1LFP-A nrPDB Length = 249 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 30/201 (14%), Positives = 57/201 (28%), Gaps = 35/201 (17%) Query: 135 EFKRSPVPIVLAASVEEQEETPSV--AIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPI 192 E + V+ V D V+ + K ++ G Sbjct: 76 ELEGEQFEEVIYEGYAPGGVAVMVLATTDNRNRTTSEVRHVFTKHGGNL----GASGCVS 131 Query: 193 NRSKKLQGYKR--ALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDE 250 ++ +GY A E + E+ + G G E I+ E Sbjct: 132 YLFER-KGYIEVPAKEVSEEELLEKAIEVGAEDVQPGEEVH------------IIYTVPE 178 Query: 251 MALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLM 310 + + G+ I + + +STV + ++LL L Sbjct: 179 ELYEVKENLEKLGVPI------------EKAQITWKPISTVQINDEETAQKVIKLLNALE 226 Query: 311 NKEPVEEHIV--ELPHRIELR 329 + V++ I E+P I + Sbjct: 227 ELDDVQQVIANFEIPEEILQK 247 >3DAF-A nrPDB Length = 358 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 42/124 (33%), Gaps = 24/124 (19%) Query: 165 AIYDAVKLLVDKG-------HTDIAFVSGPMAEPINRS-----KKLQGYKRALEE----- 207 A +AV L + G A + GP+ + + L Y+ A+ + Sbjct: 219 ASEEAVNKLYEIGKIARGKAFKMPANLIGPVCDMCSAVTATVYAGLLAYRDAVTKILGAP 278 Query: 208 ---ANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGL 264 A + +E + + G+ ++ + P A+L D M G + L Sbjct: 279 ADFAQMMADEALTQIHNLMKEKGIANMEEAL----DPAALLGTADSMCFGPLAEILPTAL 334 Query: 265 SIPE 268 + E Sbjct: 335 KVLE 338 >5YDP-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKPT 33 S +T+ DVA+ A +S T+ + Sbjct: 65 SAVTMSDVAKAAGLSRQTLYSTFGNRQGLAQA 96 >2NP5-A nrPDB Length = 203 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 26/174 (14%), Positives = 55/174 (31%), Gaps = 21/174 (12%) Query: 1 MSNITIYDVAREANVSMATVSRVVNGNPNVKP-TTRKKVLEAIERLGYRPNAV--ARGLA 57 + ++ +VA+ A VS+ V + + R V + + RL AR L Sbjct: 27 LEGASVREVAKRAGVSIGAVQHHFSTKDEMFAFALRTLVDKLLARLSEVERGGDPARALF 86 Query: 58 SKKTTTV--------------GVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNM 103 + + + + +S +E+ R +++ Sbjct: 87 AAMSQLLPLDEARSREAHVMAAFAVRAATSPSLAEIRRKTLFTIRTGLSAVLIGIG--TP 144 Query: 104 EKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPS 157 E E +L VDG+ + E+ + I + ++ + PS Sbjct: 145 EAETRA--ALLLATVDGLALDAIGSPALYPPEYLEHALDIQIGMILQGADVVPS 196 >5AWV-A nrPDB Length = 523 Score = 29.0 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%) Query: 258 AAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVA 302 A+ G+ +P D+ + N S + P L+T P +D+ Sbjct: 453 YAETGGVPVPNDVSDGAYINYPDSDLADPGLNTSGVPWHDLYYKG 497 >3KTS-A nrPDB Length = 192 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 25/59 (42%) Query: 117 QVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVD 175 Q D I + G I ++ ++ +P++ +E E+ V A+ + K L + Sbjct: 127 QPDCIELLPGIIPEQVQKMTQKLHIPVIAGGLIETSEQVNQVIASGAIAVTTSNKHLWE 185 >3E70-C nrPDB Length = 328 Score = 29.0 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 29/81 (35%), Gaps = 1/81 (1%) Query: 190 EPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATD 249 I + + + +A P+ FV + + L + + + + +++A+D Sbjct: 108 SEILETSRRIDLIEEIRKAEKPYVIMFVGFNGSGKTTTIAKLANWL-KNHGFSVVIAASD 166 Query: 250 EMALGIIHAAQDQGLSIPEDL 270 G I ++ I + Sbjct: 167 TFRAGAIEQLEEHAKRIGVKV 187 >5D1W-A nrPDB Length = 217 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 2 SNITIYDVAREANVSMATVSRVVNGNPNVKP 32 S IT+ DVAR A +S T+ + Sbjct: 42 SAITLSDVARAAGISRQTIYNEFGSRQGLAQ 72 >4MCX-A nrPDB Length = 104 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRP 49 ++ A V+ ATVSR++ G + P+ ++ A LG P Sbjct: 21 GVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAA---LGSTP 64 >6CHV-A nrPDB Length = 121 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRP 49 ++ A V+ ATVSR++ G + P+ ++ A LG P Sbjct: 38 GVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAA---LGSTP 81 >6CF1-A nrPDB Length = 138 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRP 49 ++ A V+ ATVSR++ G + P+ ++ A LG P Sbjct: 55 GVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAA---LGSTP 98 >4MCT-A nrPDB Length = 125 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRP 49 ++ A V+ ATVSR++ G + P+ ++ A LG P Sbjct: 21 GVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAA---LGSTP 64 >4I4I-A nrPDB Length = 319 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 18/42 (42%) Query: 103 MEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIV 144 E + + + ++G+V +GG+ + + + P V Sbjct: 79 EEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCV 120 >4PEV-A nrPDB Length = 422 Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 4/32 (12%) Query: 245 LSATDEMALGIIHAAQDQGLSI----PEDLDI 272 LS D ALG AA++ G+ + P+ L + Sbjct: 67 LSFNDMAALGADRAAEELGVDVVFQTPQSLAV 98 >1X18-E nrPDB Length = 231 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 21/58 (36%), Gaps = 1/58 (1%) Query: 113 MLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEE-TPSVAIDYEQAIYDA 169 +L + D I + V E ++ +P++ A + + + + AI Sbjct: 145 LLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSI 202 >2GP6-A nrPDB Length = 434 Score = 28.2 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 57/177 (32%), Gaps = 34/177 (19%) Query: 32 PTTRKKVLEAIERLG---YRPNAVARGLASKKTTTVGVIIP--------DISSIFYSELA 80 R + ++A+ L Y PN A + ++ GV+ P + + + ++ Sbjct: 143 DDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIV 202 Query: 81 RGIEDIATMYK-------------YNIILSNSDQNMEKELHLLNTMLGKQVDGIVF---- 123 G D A + + S N + + DG VF Sbjct: 203 LGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNN-DDPAGACRPFDRDR-DGFVFGEGG 260 Query: 124 -MGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDY--EQAIYDAVKLLVDKG 177 + T+EH + + + + + + VA D E+A + + + G Sbjct: 261 ALLLIETEEHAK-ARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAG 316 >2C4E-A nrPDB Length = 302 Score = 28.2 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 4/54 (7%) Query: 117 QVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAV 170 +VD ++ G+ + K+ +P + A V + P+ A D +A + + Sbjct: 207 RVDALIVTKGSKGSVIYTKDKKIEIPCIKAGKVID----PTGAGDSYRAGFLSA 256 >5KS8-A nrPDB Length = 405 Score = 27.8 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 7/60 (11%), Positives = 23/60 (38%), Gaps = 7/60 (11%) Query: 27 NPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDI 86 +P + R+ + + A+ + K TV ++ ++ ++ E+ ++ Sbjct: 176 SPQLSKAQREYIGNLAVK-------AAKAVGYKNAGTVEFLLDSDNNFYFMEMNTRLQVE 228 >2QWT-A nrPDB Length = 196 Score = 27.8 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 46/149 (30%), Gaps = 8/149 (5%) Query: 3 NITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTT 62 + + ++AR A V TV R + V+ E R AR L + + Sbjct: 32 GVPMDEIARRAGVGAGTVYRHFPTKQAL-------VVAVAEDRVRRIVDHARTLLAAEGP 84 Query: 63 TVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIV 122 + + + + G+ D Y ++ ++ L + Q G V Sbjct: 85 GEALFVFMRDMVRSAAADYGLVDALVGYGLDLEVAAPGAEAAFLATLGELLAAAQRAGTV 144 Query: 123 FMGGNITDEHVAEFKRSPVPIVLAASVEE 151 ++ A VP V V E Sbjct: 145 RADVDVA-VIKALLVVCKVPQVYDGEVSE 172 >4R28-A nrPDB Length = 456 Score = 27.8 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 6/87 (6%) Query: 49 PNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELH 108 P VAR +A + +GV + +R + +Y ++L Sbjct: 367 PEQVARVVARLRRGWIGVYVTT------GSFSRQAQVEIIDDQYPVVLIAGGTLAATVRR 420 Query: 109 LLNTMLGKQVDGIVFMGGNITDEHVAE 135 ++ G +D ++ + V Sbjct: 421 MVQANYGGDLDALLASTVDEYGAAVTH 447 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.127 0.293 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,788,241 Number of Sequences: 36641 Number of extensions: 339412 Number of successful extensions: 1592 Number of sequences better than 10.0: 78 Number of HSP's better than 10.0 without gapping: 86 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1403 Number of HSP's gapped (non-prelim): 129 length of query: 334 length of database: 10,336,785 effective HSP length: 98 effective length of query: 236 effective length of database: 6,745,967 effective search space: 1592048212 effective search space used: 1592048212 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 59 (27.4 bits)