BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P25043 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FGI-H nrPDB 504 e-143 6HV7-H nrPDB 429 e-121 6EPF-2 nrPDB 290 4e-79 5L4G-8 nrPDB 289 9e-79 6HUB-H nrPDB 266 1e-71 6AVO-B nrPDB 218 3e-57 3UNH-H nrPDB 216 1e-56 5FMG-I nrPDB 213 6e-56 5GJQ-a nrPDB 103 5e-23 6EPC-1 nrPDB 101 3e-22 5LEZ-N nrPDB 99 2e-21 5FMG-L nrPDB 96 2e-20 5MPC-h nrPDB 95 2e-20 6EPF-5 nrPDB 95 2e-20 5L64-K nrPDB 92 2e-19 5LN3-5 nrPDB 90 1e-18 3UNB-K nrPDB 89 2e-18 6HEC-1 nrPDB 88 4e-18 6AVO-A nrPDB 86 1e-17 3H4P-a nrPDB 86 1e-17 3IPM-H nrPDB 86 2e-17 3UNF-K nrPDB 84 5e-17 3NZW-K nrPDB 84 6e-17 5L5A-K nrPDB 82 3e-16 5CZ8-K nrPDB 80 7e-16 6AVO-C nrPDB 79 2e-15 3UNF-N nrPDB 73 1e-13 3H4P-A nrPDB 73 2e-13 5FMG-E nrPDB 61 5e-10 2KU2-A nrPDB 61 6e-10 5FMG-C nrPDB 59 2e-09 4FZC-A nrPDB 55 2e-08 3WXR-K nrPDB 55 3e-08 5FGE-J nrPDB 55 3e-08 5FMG-M nrPDB 54 5e-08 6HE5-A nrPDB 54 6e-08 6FVW-g nrPDB 53 1e-07 5FGG-F nrPDB 53 1e-07 5FMG-N nrPDB 53 2e-07 6J30-C nrPDB 52 2e-07 2Z5C-C nrPDB 52 2e-07 5GJR-F nrPDB 52 3e-07 5FMG-H nrPDB 51 4e-07 1G0U-D nrPDB 51 4e-07 5LF6-M nrPDB 50 8e-07 6EPE-7 nrPDB 50 1e-06 5GJQ-g nrPDB 50 1e-06 5FMG-B nrPDB 47 8e-06 2JAY-A nrPDB 44 5e-05 5LF3-J nrPDB 43 1e-04 5NYF-A nrPDB 42 2e-04 1Q5Q-H nrPDB 42 2e-04 3NZW-E nrPDB 42 2e-04 5FMG-K nrPDB 42 2e-04 1Q5R-H nrPDB 42 3e-04 5JI2-A nrPDB 41 4e-04 5LZP-A nrPDB 41 5e-04 6GOP-M nrPDB 40 0.001 5LEZ-C nrPDB 39 0.002 5LF0-A nrPDB 37 0.006 1OFH-G nrPDB 37 0.007 3NZW-L nrPDB 36 0.017 5LOY-A nrPDB 36 0.017 5T0I-L nrPDB 36 0.019 4YA5-C nrPDB 35 0.030 4HO7-A nrPDB 33 0.092 5JT8-A nrPDB 29 2.3 4PEV-A nrPDB 29 2.6 3TY6-A nrPDB 28 2.9 4B2T-Q nrPDB 27 9.4 6FEC-5 nrPDB 27 9.5 >5FGI-H nrPDB Length = 244 Score = 504 bits (1299), Expect = e-143, Method: Compositional matrix adjust. Identities = 243/244 (99%), Positives = 243/244 (99%) Query: 18 NSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT 77 NSHTQPKATSTG TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT Sbjct: 1 NSHTQPKATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT 60 Query: 78 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS 137 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS Sbjct: 61 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS 120 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG Sbjct: 121 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 180 Query: 198 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV 257 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV Sbjct: 181 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV 240 Query: 258 DITA 261 DITA Sbjct: 241 DITA 244 >6HV7-H nrPDB Length = 226 Score = 429 bits (1104), Expect = e-121, Method: Compositional matrix adjust. Identities = 204/226 (90%), Positives = 214/226 (94%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AAD EAVTQLIG Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI Sbjct: 121 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 255 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE Sbjct: 181 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 226 >6EPF-2 nrPDB Length = 277 Score = 290 bits (742), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 145/262 (55%), Positives = 190/262 (72%), Gaps = 6/262 (2%) Query: 1 MAGLSFDNYQRNNFL----AENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVA 56 + G SFDN +RN L A+ PKA TGTTI GV + +G+V+ ADTR+T+G +VA Sbjct: 11 VGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVA 70 Query: 57 DKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHL 116 DKNC+K+H ISP I+C GAGTAADT+ TQLI SN+ELHSL T R PRVV+A +MLKQ L Sbjct: 71 DKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQML 130 Query: 117 FKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLT 176 F+YQG+IGA L++ GVD TG HL+SI+ HGSTD Y+++GSGSLAAMAV E ++ D+ Sbjct: 131 FRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME 190 Query: 177 KEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPR 236 +EEA KL S+AI AGI+NDLGSGSN+D+CV+ K ++LR Y PN + + Y+ + Sbjct: 191 EEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISKSK-LDFLRPYSVPNKKGTRFGRYRCEK 249 Query: 237 GTTAVLKESIVNI-CDIQEEQV 257 GTTAVL E + + ++ EE V Sbjct: 250 GTTAVLTEKVTPLELEVLEEIV 271 >5L4G-8 nrPDB Length = 277 Score = 289 bits (739), Expect = 9e-79, Method: Compositional matrix adjust. Identities = 144/262 (54%), Positives = 189/262 (72%), Gaps = 6/262 (2%) Query: 1 MAGLSFDNYQRNNFL----AENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVA 56 + G SFDN +RN L A+ + PK TGTTI GV + +G+V+ ADTR+T+G +VA Sbjct: 11 VGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVA 70 Query: 57 DKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHL 116 DKNC+K+H ISP I+C GAGTAADT+ TQLI SN+ELHSL T R PRVV+A +MLKQ L Sbjct: 71 DKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQML 130 Query: 117 FKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLT 176 F+YQG+IGA L++ GVD TG HL+SI+ HGSTD Y+++GSGSLAAMAV E ++ D+ Sbjct: 131 FRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME 190 Query: 177 KEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPR 236 +EEA L S+AI AGI+NDLGSGSN+D+CV+ K ++LR Y PN + + Y+ + Sbjct: 191 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK-LDFLRPYTVPNKKGTRLGRYRCEK 249 Query: 237 GTTAVLKESIVNI-CDIQEEQV 257 GTTAVL E I + ++ EE V Sbjct: 250 GTTAVLTEKITPLEIEVLEETV 271 >6HUB-H nrPDB Length = 234 Score = 266 bits (679), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 130/229 (56%), Positives = 171/229 (74%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI GV + +G+V+ ADTR+T+G +VADKNC+K+H ISP I+C GAGTAADT+ TQLI Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 SN+ELHSL T R PRVV+A +MLKQ LF+YQG+IGA L++ GVD TG HL+SI+ HGSTD Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTD 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 Y+++GSGSLAAMAV E ++ D+ +EEA L S+AI AGI+NDLGSG N+D+CV+ Sbjct: 121 KLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLCVISK 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 K ++LR Y PN + + Y+ +GTTAVL E I + ++ EE V Sbjct: 181 NK-LDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETV 228 >6AVO-B nrPDB Length = 234 Score = 218 bits (554), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 109/229 (47%), Positives = 152/229 (66%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AAD E T+++ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 S +ELH+L T REPRV + ++L+Q LF+YQGH+GA LIV GVD TG L+ +H HGS Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYS 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + +LGSG AA+AVLE ++ ++T E A L +A+ AGI DLGSG NVD CV+ Sbjct: 121 RLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVI-T 179 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 A+ LR +P ++ Y F GTTAVL +++ + ++ EE V Sbjct: 180 KTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETV 228 >3UNH-H nrPDB Length = 234 Score = 216 bits (549), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 108/229 (47%), Positives = 151/229 (65%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AADTE T++ Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 S +ELH+L T REPRV + ++L+Q LF+YQGH+GA L+V GVD G L+ +H HGS Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYS 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + +LGSG AA+A+LE ++ ++T E A +L +AI AGI +DLGSG NVD CV+ Sbjct: 121 RLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITA 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 G A+ R TP ++ Y+F GTT VL + + ++ EE V Sbjct: 181 G-GAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETV 228 >5FMG-I nrPDB Length = 229 Score = 213 bits (543), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 110/219 (50%), Positives = 146/219 (66%), Gaps = 4/219 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ N V++ ADTR+T+GPIVADKNC+KLH IS IWCAGAG A D E T + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 N+ELH L T+ +PRV + L Q LFKYQG+ +++ GVD G L+ IH HGS+ Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVLGGVDVNGPQLYGIHPHGSSC 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + + +LGSGSL AMAVLE+ ++ ++T EE L +AI AGI+NDLGSG NVD+CV I Sbjct: 121 LLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICV--I 178 Query: 210 GKDA-EYLRNYLTPNVR-EEKQKSYKFPRGTTAVLKESI 246 KD+ +++R Y PN+R +P+GTT +L E I Sbjct: 179 TKDSYQHIRPYKEPNMRLYHLPHPTIYPKGTTPILSEKI 217 >5GJQ-a nrPDB Length = 239 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 57/179 (31%), Positives = 103/179 (57%), Gaps = 1/179 (0%) Query: 22 QPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADT 81 + + STGTTI+ V+F+ GVV+ AD+R+T G +A++ KL I +I+C +G+AADT Sbjct: 27 ESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADT 86 Query: 82 EAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLF 140 +AV + + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++ Sbjct: 87 QAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVY 146 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 S+ G + GSGS +++ +++ +TKEE ++ ++A+ + D SG Sbjct: 147 SVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSG 205 >6EPC-1 nrPDB Length = 238 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 56/186 (30%), Positives = 105/186 (56%), Gaps = 1/186 (0%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 + STGTTI+ V+F+ GVV+ AD+R+T G +A++ KL I I+C +G+AADT+A Sbjct: 28 REVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQA 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSI 142 V + + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++S+ Sbjct: 88 VADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSV 147 Query: 143 HAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNV 202 G + GSGS +++ +++ +TK+E ++ ++A+ + D SG + Sbjct: 148 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVI 207 Query: 203 DVCVME 208 + ++ Sbjct: 208 RLAAIQ 213 >5LEZ-N nrPDB Length = 205 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 54/174 (31%), Positives = 99/174 (56%), Gaps = 1/174 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ AD+R+T G +A++ KL I +I+C +G+AADT+AV + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSIHAHGST 148 + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++S+ G Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMM 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNV 202 + GSGS +++ +++ +TKEE ++ ++A+ + D SG + Sbjct: 121 VRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVI 174 >5FMG-L nrPDB Length = 211 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 55/176 (31%), Positives = 99/176 (56%), Gaps = 1/176 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +G+++A D+R++ G ++ +N K+ I+ I AG AAD + +G Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGST 148 I+++ L + + V +A +L L++Y+G+ + +I++G D TG ++F + G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKK 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S GSGS A ++L+S + +L ++A++LA +AI + D GSG V V Sbjct: 121 VEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRV 176 >5MPC-h nrPDB Length = 215 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 57/184 (30%), Positives = 103/184 (55%), Gaps = 6/184 (3%) Query: 27 STGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQ 86 S GT+I+ V F +GV++ AD+R+T G +A++ KL R+ KIWC +G+AADT+A+ Sbjct: 17 SLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIAD 76 Query: 87 LIGSNIELHSLYTSR--EPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS-HLFSIH 143 ++ ++E LYTS+ P +A + K+ ++ + ++ A +IVAG D +++I Sbjct: 77 IVQYHLE---LYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIP 133 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 GS Y GSGS + +++++++KEE + ++ I D SG + Sbjct: 134 LGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIR 193 Query: 204 VCVM 207 + V+ Sbjct: 194 MVVL 197 >6EPF-5 nrPDB Length = 263 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 56/177 (31%), Positives = 93/177 (52%), Gaps = 1/177 (0%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + KF +GV++AAD+R+T GP +A + K+ I+P + AG AAD +L+ Sbjct: 59 GTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGS 147 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S+GSGS+ A V++ + DL EEA LA AI + D SG V++ Sbjct: 179 RISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNL 235 >5L64-K nrPDB Length = 211 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 55/176 (31%), Positives = 96/176 (54%), Gaps = 1/176 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGST 148 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S+GSGS+ A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 121 ISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 >5LN3-5 nrPDB Length = 263 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 54/177 (30%), Positives = 92/177 (51%), Gaps = 1/177 (0%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 59 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGS 147 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S+GSGS+ A V++ + DL E+A LA AI + D SG V++ Sbjct: 179 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNL 235 >3UNB-K nrPDB Length = 205 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 54/176 (30%), Positives = 91/176 (51%), Gaps = 1/176 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGST 148 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S+GSGS+ A V++ + DL EEA LA AI + D SG V++ Sbjct: 121 ISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNL 176 >6HEC-1 nrPDB Length = 202 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 54/180 (30%), Positives = 98/180 (54%), Gaps = 6/180 (3%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT VG+ +GVV+A + R+T G +A K K+++I+ ++ AG+ D + + ++I Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHL---FKYQGHIGAYLIVAGVDPTGSHLFSIHA-H 145 L+ + R+P V A+ L +L ++Y ++ L++ G+D G ++SI Sbjct: 61 IEANLYEIRRERKP-TVRAIATLTSNLLNSYRYFPYL-VQLLIGGIDSEGKSIYSIDPIG 118 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVC 205 G+ + ++ GSGSL A VLE + ++ +EA++LA AI + + D SG +DV Sbjct: 119 GAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVV 178 >6AVO-A nrPDB Length = 199 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 52/171 (30%), Positives = 93/171 (54%), Gaps = 2/171 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ +D+R + G V ++ KL + +I+CA +G+AAD +AV + Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSIHAHGST 148 +ELH + P V++A +++ +KY+ + A+L+VAG D G ++ T Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLT 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 + + GSGS +++ +K ++ EE + +DAI + D SG Sbjct: 121 RQPFAIG-GSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSG 170 >3H4P-a nrPDB Length = 219 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 56/185 (30%), Positives = 100/185 (54%), Gaps = 11/185 (5%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT VG+ ++ V++A D R++ G +VADK KL++I I AG+ D +A+ +L+ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 90 SNIELHSLYTSREPRVVSALQMLKQ-----HLFKYQGHIGAYLIVAGVDPT-GSHLFSIH 143 + +L+ + T R ++ +L +F + I I+ G D G+ LFS+ Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQI----IIGGYDLLEGAKLFSLD 117 Query: 144 AHGS-TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNV 202 G + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ + Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 203 DVCVM 207 + V+ Sbjct: 178 SLAVI 182 >3IPM-H nrPDB Length = 217 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 4/182 (2%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGTT VG+ + V++A + R T + KN KL +I AG D + + + Sbjct: 7 TGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRY 66 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHL--FKYQGHIGAYLIVAGVDPTGSHLFSIHAH 145 + + +EL+ L + + +L L KY ++ L+V G+D T H+FSI A Sbjct: 67 MKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYM-VQLLVGGID-TAPHVFSIDAA 124 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVC 205 G + Y S GSGS VLES + + +T +E + L AI A D SG +DV Sbjct: 125 GGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMIDVA 184 Query: 206 VM 207 V+ Sbjct: 185 VI 186 >3UNF-K nrPDB Length = 204 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 93/182 (51%), Gaps = 5/182 (2%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++A D+R+T G ++ K+ I+P + +G AAD + +L+ Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG---HIGAYLIVAGVDPTGSHLFSIHAHG 146 L+ L V +A ++L + +Y+G +G+ ++ G D G L+ + +G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGS--MICGWDKKGPGLYYVDDNG 118 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCV 206 + G S GSG+ A V++S ++QDL+ EEA L AI D SG V++ Sbjct: 119 TRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYH 178 Query: 207 ME 208 M+ Sbjct: 179 MK 180 >3NZW-K nrPDB Length = 287 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 4/179 (2%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + +F G+++A D+R+T G VA + K+ I+P + AG AAD + + Sbjct: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQG---HIGAYLIVAGVDPTGSHLFSIHAH 145 GS LH L V +A ++L +++Y+G +G +I G ++ + + Sbjct: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGT-MICGYTRKEGPTIYYVDSD 193 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 194 GTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 >5L5A-K nrPDB Length = 211 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 53/177 (29%), Positives = 92/177 (51%), Gaps = 3/177 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV+ A D+R++ G ++ K+ I+P + +G AAD + L+ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL--IVAGVDPTGSHLFSIHAHGS 147 L+ L V +A ++L + +Y+G +G + ++ G D G L+ + HG+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKGPGLYYVDEHGT 119 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G S GSG+ A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 120 RLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 >5CZ8-K nrPDB Length = 221 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 53/179 (29%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + +F G+++A D+R+T G VA + + I+P + AG AAD + + Sbjct: 9 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWETWL 68 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQG---HIGAYLIVAGVDPTGSHLFSIHAH 145 GS LH L V +A ++L +++Y+G +G +I G ++ + + Sbjct: 69 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGT-MICGYTRKEGPTIYYVDSD 127 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 128 GTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 186 >6AVO-C nrPDB Length = 204 Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 52/181 (28%), Positives = 91/181 (50%), Gaps = 3/181 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV+ A D+R++ G ++ K+ I+P + +G AAD + +L+ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL--IVAGVDPTGSHLFSIHAHGS 147 L+ L V +A ++L + +Y+G +G + ++ G D G L+ + HG+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKGPGLYYVDEHGT 119 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 207 G S GSG+ A V++S ++ +L+ EEA L AI D SG V++ M Sbjct: 120 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHM 179 Query: 208 E 208 + Sbjct: 180 K 180 >3UNF-N nrPDB Length = 199 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 53/171 (30%), Positives = 92/171 (53%), Gaps = 2/171 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ +D+R + G V ++ KL + +I+CA +G+AAD +A+ + Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSIHAHGST 148 +ELH L P V++A ++K +KY+ + A+LIVAG D G ++ Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYGTMGGMLI 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 + + GSGS +++ +K +T EE + ++AI + D SG Sbjct: 121 RQPFTIG-GSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSG 170 >3H4P-A nrPDB Length = 264 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 17/201 (8%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A GTT +G+ +GVV+A D R T +V ++ K+ +I + A +G AD Sbjct: 33 EAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARV 91 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFK----YQGH-----IGAYLIVAGVDP 134 + +++ L E +++ML + + Y H G L++AG+D Sbjct: 92 LIDRARLEAQIYRLTYGEE----ISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK 147 Query: 135 TGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWN 194 + LF G+ ++GSG M +LE ++ D+T +E ++LA A+ N Sbjct: 148 NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--N 205 Query: 195 DLGSGSNVDVCVMEIGKDAEY 215 + NVDVC++ + KDA++ Sbjct: 206 EDIKPENVDVCIITV-KDAQF 225 >5FMG-E nrPDB Length = 256 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 48/196 (24%), Positives = 87/196 (44%), Gaps = 14/196 (7%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 A G+T VG+ N+GV++A++ R + I D + KL I I CA +G AD + Sbjct: 30 AIKLGSTAVGICVNDGVILASERRISSTLIEKD-SVEKLLSIDDHIGCAMSGLMADARTL 88 Query: 85 TQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG------------HIGAYLIVAGV 132 + + + S ++++ + + G L++ GV Sbjct: 89 IDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGV 148 Query: 133 DPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGI 192 D G L+ G+ S+GS A +L+ ++K+D+T E+A LA ++ + Sbjct: 149 DKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQ-V 207 Query: 193 WNDLGSGSNVDVCVME 208 D S SNV++C ++ Sbjct: 208 MEDKLSTSNVEICAIK 223 >2KU2-A nrPDB Length = 237 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 24/183 (13%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+KF NGV++ +D + + ++ + K+ I + +G AD Sbjct: 33 EAVKKGSTALGMKFANGVLLISD-KKVRSRLIEQNSIEKIQLIDDYVAAVTSGLVADARV 91 Query: 84 VTQL-----------IGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAY---LIV 129 + GS + + +L RV +Q Q+ G + Y LI Sbjct: 92 LVDFARISAQQEKVTYGSLVNIENLVK----RVADQMQQYTQY-----GGVRPYGVSLIF 142 Query: 130 AGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 AG+D G LF G+ + ++GSG A ++ LE +K++L ++EA+ L A++ Sbjct: 143 AGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALK 202 Query: 190 AGI 192 + + Sbjct: 203 SSL 205 >5FMG-C nrPDB Length = 246 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 56/219 (25%), Positives = 98/219 (44%), Gaps = 15/219 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A + + +G+ +GV++ AD I N K+++I I+C AG AD Sbjct: 26 EAINNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADA-- 83 Query: 84 VTQLIGSNIELHS---LYTSREPRVVSALQM----LKQHLFKYQG--HIGAYLIVAGVDP 134 ++ + L++ LY E + VS L + +KQ +Y G G ++ G D Sbjct: 84 --NILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDT 141 Query: 135 T-GSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIW 193 G L+ G+ + ++G+ +L A +VL+ WK D+T EE + LA + Sbjct: 142 KDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTD 201 Query: 194 NDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSY 232 ++ +++ + KD E + YLT EE K Y Sbjct: 202 TEIPKSEKIELAYL-TNKDGEVYQKYLTEKEIEELIKLY 239 >4FZC-A nrPDB Length = 250 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 87/190 (45%), Gaps = 9/190 (4%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 A G T +G+K NGVVIA + +S+ P+ + +K+ ++P I +G D + Sbjct: 27 AVKQGVTSLGIKATNGVVIATEKKSSS-PLAMSETLSKVSLLTPDIGAVYSGMGPDYRVL 85 Query: 85 TQLIG--SNIELHSLYTSREPR--VVSALQMLKQHLFKYQG--HIGAYLIVAGVDP-TGS 137 ++ +Y P +VS + + Q + G G L++AG D G Sbjct: 86 VDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGF 145 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 L+ + GS ++G GS+AA LE W +L E+AI +A ++ + + Sbjct: 146 SLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGEF- 204 Query: 198 SGSNVDVCVM 207 +G +++ ++ Sbjct: 205 NGDTIELAII 214 >3WXR-K nrPDB Length = 238 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I +N Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 92 IELHSLYTSRE--PRVVSALQMLKQHLFK-------YQGHIGAYLIVAGVDPTGS--HLF 140 I+L+S+ E P+ VS+ ++Q L K YQ ++ ++ G D + L+ Sbjct: 64 IQLYSIREDYELSPQAVSSF--VRQELAKSIRSRRPYQVNV----LIGGYDKKKNKPELY 117 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 I G+ Y + G ++L+ H++ D+T EE + L +Q Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQ 166 >5FGE-J nrPDB Length = 198 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I +N Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 92 IELHSLYTSRE--PRVVSALQMLKQHLFK-------YQGHIGAYLIVAGVDPTGS--HLF 140 I+L+S+ E P+ VS+ ++Q L K YQ ++ ++ G D + L+ Sbjct: 64 IQLYSIREDYELSPQAVSSF--VRQELAKSIRSRRPYQVNV----LIGGYDKKKNKPELY 117 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 I G+ Y + G ++L+ H++ D+T EE + L +Q Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQ 166 >5FMG-M nrPDB Length = 240 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 45/194 (23%), Positives = 88/194 (45%), Gaps = 18/194 (9%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 G T++G+ + V++AADTR + + + C K+ +++ K +G +D + + L+ Sbjct: 37 GGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSLL 96 Query: 89 GSNIELHSLYTSREPRVVSALQML-----KQHLFKYQGHIGAYLIVAGVDPTGSH-LFSI 142 I+L L S P + ++L + F Y A+ I+AGVD L++ Sbjct: 97 QKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYY----AFNILAGVDENNKGVLYNY 152 Query: 143 HAHGSTDVGYYLSLGSGSLAAMAVLESHWKQ--------DLTKEEAIKLASDAIQAGIWN 194 + GS + +GSGS + +L++ +Q + + I DAI + Sbjct: 153 DSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATER 212 Query: 195 DLGSGSNVDVCVME 208 D+ +G + V++ Sbjct: 213 DIYTGDKTLIYVID 226 >6HE5-A nrPDB Length = 247 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 48/179 (26%), Positives = 78/179 (43%), Gaps = 9/179 (5%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G T +G+K GV++ AD R + AD K+++I I A +G AD Sbjct: 30 EAVKRGATAIGIKCKEGVILIADKRVGSKLLEAD-TIEKIYKIDEHICAATSGLVADARV 88 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQM----LKQHLFKYQG--HIGAYLIVAGVDPTGS 137 + +++ L T EP V L KQ +Y G G L++AGVD Sbjct: 89 LIDRARIEAQINRL-TYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV-P 146 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDL 196 L+ G+ ++G G A E ++ DL+ ++A+ L A+ I ++L Sbjct: 147 KLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESEL 205 >6FVW-g nrPDB Length = 245 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 74/193 (38%), Gaps = 49/193 (25%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAAD--- 80 KA GTT +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 26 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 84 Query: 81 ---------------------TEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY 119 A +G ++ H+LY S P Sbjct: 85 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRP---------------- 128 Query: 120 QGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYY-LSLGSGSLAAMAVLES---HWKQDL 175 G I GVD G+HL+ + GS GY + G G +A A LE H + L Sbjct: 129 ---FGVSTIFGGVDKNGAHLYMLEPSGSY-WGYKGAATGKGRQSAKAELEKLVDHHPEGL 184 Query: 176 TKEEAIKLASDAI 188 + EA+K A+ I Sbjct: 185 SAREAVKQAAKII 197 >5FGG-F nrPDB Length = 288 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 74/193 (38%), Gaps = 49/193 (25%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTE- 82 KA GTT +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 Query: 83 -----------------------AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY 119 A +G ++ H+LY S P Sbjct: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRP---------------- 131 Query: 120 QGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYY-LSLGSGSLAAMAVLE---SHWKQDL 175 G I GVD G+HL+ + GS GY + G G +A A LE H + L Sbjct: 132 ---FGVSTIFGGVDKNGAHLYMLEPSGSY-WGYKGAATGKGRQSAKAELEKLVDHHPEGL 187 Query: 176 TKEEAIKLASDAI 188 + EA+K A+ I Sbjct: 188 SAREAVKQAAKII 200 >5FMG-N nrPDB Length = 265 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 49/239 (20%), Positives = 95/239 (39%), Gaps = 43/239 (17%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++ +K+ +G++IAAD +++ G +N ++ +I+ K +G AD + + +L Sbjct: 8 TGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLHEL 67 Query: 88 --------IGSNIELHSLYTSRE-----PRVVSALQMLKQHLF-----------KYQGHI 123 + +YT + RV + LF KY + Sbjct: 68 LTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYDNND 127 Query: 124 GAYLIVAG------------------VDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMA 165 L+ + ++ + HG+ Y++ G A+ Sbjct: 128 DNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFALT 187 Query: 166 VLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNV 224 +L H+K ++T+EEA L ++ ++ + D + SN V K EY Y+ P V Sbjct: 188 LLRDHYKDNMTEEEARILINECLRILYFRD-ATSSNFIQIVKVTSKGVEYEEPYILPCV 245 >6J30-C nrPDB Length = 258 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 47/161 (29%), Positives = 83/161 (51%), Gaps = 8/161 (4%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV--TQLI 88 T +G+ ++G+V+AA+ + T + D + KL++++ KI A AG AD E + T I Sbjct: 34 TAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARI 93 Query: 89 GSNIELHSLYTSREPR--VVSALQMLKQHLFKYQG--HIGAYLIVAGVDPT-GSHLFSIH 143 + L + Y P +V L +KQ ++ G G I AG D G L++ + Sbjct: 94 HAQNYLKT-YNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSN 152 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLA 184 G+ +S+G+ + AA +L+ +K D+ ++AI+LA Sbjct: 153 PSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELA 193 >2Z5C-C nrPDB Length = 262 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 49/171 (28%), Positives = 77/171 (45%), Gaps = 17/171 (9%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+ GVV+ + R+T P++ + K+ I I CA +G AD + Sbjct: 31 EAIKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARS 89 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY-QGH----------IGAYLIVAGV 132 + + + H+LY + V S Q + ++ +G G L++AG Sbjct: 90 MIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGH 149 Query: 133 DP-TGSHLFSIHAHGSTDVGYY--LSLGSGSLAAMAVLESHWKQDLTKEEA 180 D G LF HA S Y ++GSGS A A L + W LT +EA Sbjct: 150 DADDGYQLF--HAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEA 198 >5GJR-F nrPDB Length = 241 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/201 (24%), Positives = 93/201 (46%), Gaps = 16/201 (7%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G++ + GV +A + R T P++ + K+ I I CA +G AD A Sbjct: 29 EAIKLGSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIAD--A 85 Query: 84 VTQLIGSNIELHS-LYTSREPRVVSALQMLKQHLFKYQGH-----------IGAYLIVAG 131 T + + +E + +T E V ++ +L G G L+ G Sbjct: 86 KTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGG 145 Query: 132 VDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 191 VD G LF + G+ ++GS S A + L+ + + +T +EAIK +S I Sbjct: 146 VDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIK-SSLIILKQ 204 Query: 192 IWNDLGSGSNVDVCVMEIGKD 212 + + + +N+++ ++ G++ Sbjct: 205 VMEEKLNATNIELATVQPGQN 225 >5FMG-H nrPDB Length = 252 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 42/59 (71%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 TTI+G+ ++NGV++A D+R++ G +++K K++RI+ ++ +G +A ++ + ++I Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEII 59 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 98 YTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSH-LFSIHAHGSTDVGYYLSL 156 + P V + + K+ ++ + LI G D L++++ +GS + ++ Sbjct: 122 FNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDFAV 181 Query: 157 -GSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 GSGS+ + L+ +K+ +TK+E L + ++ + ND SG Sbjct: 182 SGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSG 225 >1G0U-D nrPDB Length = 241 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 48/162 (29%), Positives = 73/162 (45%), Gaps = 8/162 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+ GVV+ + R+T P++ + K+ I I CA +G AD + Sbjct: 29 EAIKLGSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSGLTADARS 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQ--HLFKYQGHIGAYLIVAGVDP-TGSHLF 140 + + + H+LY + V S Q + G L++AG D G LF Sbjct: 88 MIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMSRPFGVALLIAGHDADDGYQLF 147 Query: 141 SIHAHGSTDVGYY--LSLGSGSLAAMAVLESHWKQDLTKEEA 180 HA S Y ++GSGS A A L + W LT +EA Sbjct: 148 --HAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEA 187 >5LF6-M nrPDB Length = 219 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 7 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 66 Query: 88 IGSNI---ELHSLYTSREPRVV 106 +G + EL S PR + Sbjct: 67 LGQMVIDEELLGDGHSYSPRAI 88 >6EPE-7 nrPDB Length = 263 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF+ GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 51 TGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQV 110 Query: 88 IGSNI---ELHSLYTSREPRVV 106 +G + EL S PR + Sbjct: 111 LGQMVIDEELFGDGHSYSPRAI 132 >5GJQ-g nrPDB Length = 264 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 52 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111 Query: 88 IGSNI---ELHSLYTSREPRVV 106 +G + EL S PR + Sbjct: 112 LGQMVIDEELLGDGHSYSPRAI 133 >5FMG-B nrPDB Length = 235 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 6/164 (3%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 S+ + +G++ NGV+IA + +S ++ + + K+ +IS I AG D + Sbjct: 29 VSSSSPALGIRAKNGVIIATEKKSPN-ELIEENSIFKIQQISEHIGIVYAGMPGDFRVLL 87 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHL--FKYQGHI---GAYLIVAGVDPTGSHLF 140 + +SL E V ++++ + F G + G L++ GVD G HL+ Sbjct: 88 KRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVYGYHLY 147 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLA 184 I G +G M+ LE + +D+ E+AI A Sbjct: 148 QIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTA 191 >2JAY-A nrPDB Length = 291 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 18/186 (9%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTTIV +K+ GVV+A D RSTQG +++ ++ K++ AGTAA +L Sbjct: 57 GTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLY 116 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGA-------------YLIVAGVDPT 135 +E H Y E ++ + + +G++ A Y I A + Sbjct: 117 AVELE-H--YEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQS 173 Query: 136 GSHLFSIHAHGSTDVGY--YLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIW 193 + S A G ++ Y ++GSGSL A + ++ + Q + +++A +A+ Sbjct: 174 AGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAAD 233 Query: 194 NDLGSG 199 +D +G Sbjct: 234 DDSATG 239 >5LF3-J nrPDB Length = 201 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/162 (18%), Positives = 76/162 (46%), Gaps = 4/162 (2%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 ++G++ + V++A+D + + + K+ ++S KI G A DT + I N Sbjct: 4 LIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKN 63 Query: 92 IELHSLYTSREPRVVSALQMLKQHL---FKYQGHIGAYLIVAGVDP-TGSHLFSIHAHGS 147 ++L+ + E +A +++L + + L++AG D G L+ + + Sbjct: 64 VQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAA 123 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 + + G G+ +++L+ ++ +++E A++L ++ Sbjct: 124 LAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLE 165 >5NYF-A nrPDB Length = 245 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 60/239 (25%), Positives = 94/239 (39%), Gaps = 65/239 (27%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIW---------CAGAGTAA 79 GT V + G+V AADTR+ G N A+ ++ ++W AG A Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGV----DNIAQYKKL--QLWRQPGERVFVLLSAGNLA 55 Query: 80 DTEAVTQLIGSNI------ELHSLYTS----REPRVV------------SALQMLKQHL- 116 T+AV LI ++ E+ +L+T+ R RVV +AL+ K Sbjct: 56 ATQAVVSLINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFN 115 Query: 117 --FKYQGHIGAYLIVAGVDPTGSHLFSIHAHG----STDVGYYLSLGSGSLAAMAVLESH 170 F + G I G P LF I+ G +TD + +G +L+ Sbjct: 116 TNFIFGGQI------KGERP---RLFQIYPEGNFIEATDDTPFFQIGEHKYGK-PILDRV 165 Query: 171 WKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME-----------IGKDAEYLRN 218 + D+ EA KL + + + ++L G +D+ + E I D EY RN Sbjct: 166 ARSDMRLGEAAKLMLLSFDSTLRSNLSVGMPIDLVIYERDTFDVTREKRISADDEYFRN 224 >1Q5Q-H nrPDB Length = 235 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 22/187 (11%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAG-AGTAADTEAVTQLI 88 TTIV + + GV++A D R+TQG ++A ++ K++ ++ + AG AGTA + +L Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVY-VTDEYSAAGIAGTAGIAIELVRLF 59 Query: 89 GSNIELHS-------LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVD------PT 135 +E + + + R+ S M++ +L + ++ G D Sbjct: 60 AVELEHYEKIEGVPLTFDGKANRLAS---MVRGNLGAAMQGLAVVPLLVGYDLDADDESR 116 Query: 136 GSHLFSIHAHGST---DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGI 192 + S G GY+ ++GSGSL A + L+ + D +E A++ A +++ Sbjct: 117 AGRIVSYDVVGGRYEERAGYH-AVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 175 Query: 193 WNDLGSG 199 +D +G Sbjct: 176 DDDSATG 182 >3NZW-E nrPDB Length = 234 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 86/201 (42%), Gaps = 14/201 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+ VG++ N V+ A R+ K K+ + + + AG A D Sbjct: 27 EAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQK---KIIKCDEHMGLSLAGLAPDARV 83 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQML----KQHLFKYQGH-IGAYLIVAGVDPTGSH 138 ++ + SL +R+ V A +L +++ Y G G L++ G D +G+H Sbjct: 84 LSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAH 143 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLE----SHWKQDLTKEEAIKLASDAIQAGIWN 194 L G+ Y ++G+ S A LE + K D +E IK +AI + + Sbjct: 144 LLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRD 203 Query: 195 DLGSGSNVDVCVMEIGKDAEY 215 + + N+ + + +GKD + Sbjct: 204 ESLTVDNLSIAI--VGKDTPF 222 >5FMG-K nrPDB Length = 195 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 4/157 (2%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPI-VADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 T++G++ NN VV+AADT S I + + + K + I G+ D + I Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKY--QGHIGAYLIVAGVDPT-GSHLFSIHAHG 146 N+ L+ + + V S +++L Y + ++AG D G L+ Sbjct: 63 KNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLS 122 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKL 183 + D + G G+ A+L+ ++ ++LT +EA+ + Sbjct: 123 NMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDI 159 >1Q5R-H nrPDB Length = 294 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 87/188 (46%), Gaps = 22/188 (11%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAG-AGTAADTEAVTQL 87 GTTIV + + GV++A D R+TQG ++A ++ ++ ++ + AG AGTA + +L Sbjct: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVY-VTDEYSAAGIAGTAGIAIELVRL 123 Query: 88 IGSNIELHS-------LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVD------P 134 +E + + + R+ S M++ +L + ++ G D Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLAS---MVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 Query: 135 TGSHLFSIHAHGST---DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 191 + S G GY+ ++GSGSL A + L+ + D +E A++ A +++ Sbjct: 181 RAGRIVSYDVVGGRYEERAGYH-AVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 Query: 192 IWNDLGSG 199 +D +G Sbjct: 240 ADDDSATG 247 >5JI2-A nrPDB Length = 184 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQLI 88 TTIV V+ N VVIA D ++T G V N K+ R+ + K+ AG AD + +L Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 89 GSNIELH 95 +E+H Sbjct: 62 ERKLEMH 68 >5LZP-A nrPDB Length = 242 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 18/184 (9%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGS 90 TIV +K+ GVV+A D RSTQG +++ ++ K++ AGTAA +L Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 91 NIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGA-------------YLIVAGVDPTGS 137 +E H Y E ++ + + +G++ A Y I A + Sbjct: 62 ELE-H--YEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 118 Query: 138 HLFSIHAHGSTDVGY--YLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWND 195 + S A G ++ Y ++GSGSL A + ++ + Q + +++A +A+ +D Sbjct: 119 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 178 Query: 196 LGSG 199 +G Sbjct: 179 SATG 182 >6GOP-M nrPDB Length = 246 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 47/225 (20%), Positives = 95/225 (42%), Gaps = 24/225 (10%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++ +K++NGV+IAAD + G ++ +L + +G +D + + +L Sbjct: 20 TGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERL 79 Query: 88 IGSNI-------ELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAY---LIVAGVDPTGS 137 + + L + EP + + L +++ + + +IVAGV G Sbjct: 80 LKDLVTENAYDNPLADAEEALEPSYI--FEYLATVMYQRRSKMNPLWNAIIVAGVQSNGD 137 Query: 138 HLFS-IHAHGSTDVGYYLSLGSGSLAAMAVLES--HWKQDLTK------EEAIKLASDAI 188 ++ G T L+ G G+ A +L + D+ K EEAI +A+ Sbjct: 138 QFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAI---VNAM 194 Query: 189 QAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYK 233 + + D S N + +++ + +N N++ + K K Sbjct: 195 RVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIK 239 >5LEZ-C nrPDB Length = 248 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 22/198 (11%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T VGV+ + VV+ + +S + ++ K+ + + A AG AD Sbjct: 24 EAVKKGSTAVGVRGRDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQM----LKQHLFKYQGH--IGAYLIVAGVDPTGS 137 V + H L T +P V + LKQ + G G ++ G D G+ Sbjct: 83 VINRARVECQSHRL-TVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGT 141 Query: 138 -HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHW------KQDLTKEEAIKLASDAIQA 190 L+ G+ ++G G+ + LE ++ DLT + IK + +Q+ Sbjct: 142 PRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQS 201 Query: 191 GIWNDLGSGSNVDVCVME 208 G G N+++ VM Sbjct: 202 G-------GKNIELAVMR 212 >5LF0-A nrPDB Length = 234 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 48/198 (24%), Positives = 78/198 (39%), Gaps = 33/198 (16%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVAD-KNCAKLHRISPKIWCAGAGTAADTEA 83 A + G VG+K NGVV+A T Q I+ D ++ K+ I+ I +G D Sbjct: 28 AVAGGAPSVGIKAANGVVLA--TEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRV 85 Query: 84 VTQLIGSNIELHSLYTSREP--------RVVSALQMLKQHLFKYQGHI---GAYLIVAGV 132 + + + L +EP RV S +Q Q G + G L++ G Sbjct: 86 LVHRARKLAQQYYL-VYQEPIPTAQLVQRVASVMQEYTQ-----SGGVRPFGVSLLICGW 139 Query: 133 DPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAI----------- 181 + +LF G+ ++G + LE + +DL E+AI Sbjct: 140 NEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESF 199 Query: 182 --KLASDAIQAGIWNDLG 197 ++ D I+ GI N+ G Sbjct: 200 EGQMTEDNIEVGICNEAG 217 >1OFH-G nrPDB Length = 174 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 25/170 (14%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQLI 88 TTIV V+ N VV+ D + + G V N K+ R+ + K+ AG AD + +L Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 89 GSNIELH-------SLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAG----VDPTGS 137 +E+H ++ +++ R AL+ L+ L LI+ G V P Sbjct: 61 ERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEK--ESLIITGIGDVVQPEED 118 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLE-SHWKQDLTKEEAIKLASD 186 + +I + G+ Y LS AA A++E + E+++++A D Sbjct: 119 QILAIGSGGN----YALS------AARALVENTELSAHEIVEKSLRIAGD 158 >3NZW-L nrPDB Length = 241 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 43/201 (21%), Positives = 88/201 (43%), Gaps = 22/201 (10%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 G TI+G+ + V+A DTR+ + + K+ I + G AAD +A+ + Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 88 IGSNIE-LHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL--IVAGVDPTGS-HLFSIH 143 ++++ H + ++ + SA + + QHL + Y+ I+AG+D G ++S Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNI-QHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFD 145 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLES--HWKQD---------------LTKEEAIKLASD 186 GS + + G+ + M L++ ++K L+ EE IKL D Sbjct: 146 PVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRD 205 Query: 187 AIQAGIWNDLGSGSNVDVCVM 207 + + + G +++ ++ Sbjct: 206 SFTSATERHIQVGDGLEILIV 226 >5LOY-A nrPDB Length = 240 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 49/219 (22%), Positives = 84/219 (38%), Gaps = 33/219 (15%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK----IWCAGAGTAADTEAVT 85 T VG++ + G+V A+D+R+ G + K+H I AG A T+AV Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAG-VDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVI 59 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS-------- 137 L+ ++ P + A +++ + L + Q L GVD S Sbjct: 60 SLLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIA 119 Query: 138 ----HLFSIHAHG----STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 LF I+ G +T + +G +L+ D + E+A K A + Sbjct: 120 GEPPRLFLIYPAGNFIEATPDTPFFQIGETKYGK-PILDRVITPDTSLEDAAKCALVSFD 178 Query: 190 AGIWNDLGSGSNVDVCVME-----------IGKDAEYLR 217 + + ++L G +D+ V E I +D Y R Sbjct: 179 STMRSNLSVGLPLDLLVYERDSLRVGHRRRIDEDDPYFR 217 >5T0I-L nrPDB Length = 268 Score = 35.8 bits (81), Expect = 0.019, Method: Compositional matrix adjust. Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 21/204 (10%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+ VG+K V+ A R+ Q + A + K+ + I + AG AD Sbjct: 32 EAVKQGSATVGLKSKTHAVLVALKRA-QSELAAHQK--KILHVDNHIGISIAGLTADARL 88 Query: 84 VTQLIGSNIELHSLYTSREPRVVSAL--------QMLKQHLFKYQGHIGAYLIVAGVDPT 135 + + L S + P VS L Q+ Q + +G L++AG D Sbjct: 89 LCNFMRQEC-LDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVG--LLIAGYDDM 145 Query: 136 GSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQ--DLTKEEAIKLASDAIQAGI- 192 G H+F + +S+G+ S +A LE H + + E +K A++ + Sbjct: 146 GPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLP 205 Query: 193 -WNDLGSGSNVDVCVMEIGKDAEY 215 DL + NV + + +GKD E+ Sbjct: 206 AEQDL-TTKNVSIGI--VGKDLEF 226 >4YA5-C nrPDB Length = 254 Score = 35.0 bits (79), Expect = 0.030, Method: Compositional matrix adjust. Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 28/218 (12%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A GT VGVK N VV+ + RST +K+ +I + + +G AD+ Sbjct: 25 EAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRI 84 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQML---KQHLFKYQGHI---GAYLIVAGVDPTGS 137 + + + H L T +P V L Q + G + G ++AG DP Sbjct: 85 LIEKARVEAQSHRL-TLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDD 143 Query: 138 H--LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQD---LTKEEAIKLAS----DAI 188 L+ G ++G S LE ++ + T EE +KL + + Sbjct: 144 EPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVV 203 Query: 189 QAGIWNDLGSGSNVDVCVMEIGKD-----AEYLRNYLT 221 Q G N+++ V++ D +E + Y+T Sbjct: 204 QTG-------AKNIEITVVKPDSDIVALSSEEINQYVT 234 >4HO7-A nrPDB Length = 179 Score = 33.5 bits (75), Expect = 0.092, Method: Compositional matrix adjust. Identities = 51/190 (26%), Positives = 84/190 (44%), Gaps = 28/190 (14%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGP-IVADKNCAKLHRISPKIWCAGAGTAADT----EAV 84 TTI+ V+ + VV+ D + T G IVA + KL RI+ + AG+ AD E + Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 85 TQLIG---SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFS 141 IG + + ++ ++E R AL+ L+ A LIV + T Sbjct: 61 ENKIGEFPNQLTRAAVELAKEWRTDRALRRLE-----------ASLIVCSAEET----LE 105 Query: 142 IHAHGST---DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGS 198 I G+ + +++GSG A A + D+ +A K+A A++ D+ S Sbjct: 106 IDGQGNVITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDIDVFS 163 Query: 199 GSNVDVCVME 208 + DV V+E Sbjct: 164 NEHWDVEVLE 173 >5JT8-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 9/107 (8%) Query: 64 HRISPKIWCAGAGTAADTEAVTQLIGSNI--ELHSLYTSREPRVVSALQMLKQHLFKYQG 121 +R P C G G+ TEA +I + + E + Y R ++ + H+ YQ Sbjct: 171 NRYDPSYQCNGCGSGYSTEAFKYMIRTGLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQ 230 Query: 122 ---HIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMA 165 H ++ + G + I+ HGS + Y+ +LG+G L +A Sbjct: 231 LRYHSSDEDVMYTIQQHGPVV--IYMHGSNN--YFRNLGNGVLRGVA 273 >4PEV-A nrPDB Length = 422 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 9/91 (9%) Query: 68 PKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSR--EPRV--VSALQMLKQHLFKYQG-- 121 P +W G + Q +G+++E+ YT R +P + +A QML+Q + + G Sbjct: 196 PPLWRFHIGYLYGVQYYNQAMGTDVEMVWTYTGRFDDPTLGKTTAEQMLQQGVRVFYGVA 255 Query: 122 ---HIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 H+G + V G FSI S + Sbjct: 256 GLTHVGMFNAVKEAAARGVIAFSIGQDASQE 286 >3TY6-A nrPDB Length = 183 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHR--ISPKIWCAGAGTAADTEAVTQL 87 TTI V N +A D + T G V K+ A+ R K+ AG+ AD + ++ Sbjct: 10 TTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEM 69 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQ 114 +E ++ R +A++M KQ Sbjct: 70 FEGKLEEYNGNLQR-----AAVEMAKQ 91 >4B2T-Q nrPDB Length = 548 Score = 26.9 bits (58), Expect = 9.4, Method: Compositional matrix adjust. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 60 CAKLHRISPKIWCAGAGTAADTEAVTQLIGSNI 92 C K H I P + C A D + V+ L+ +++ Sbjct: 136 CKKAHEILPDLVCCSAKNLRDVDEVSSLLHTSV 168 >6FEC-5 nrPDB Length = 352 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 31/66 (46%) Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 VG+Y S GS A+L+S + EE++ L D I+ + + +ME+ Sbjct: 117 VGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEV 176 Query: 210 GKDAEY 215 K+ ++ Sbjct: 177 CKEKDF 182 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FGI-H nrPDB 340 4e-94 6EPF-2 nrPDB 324 2e-89 5L4G-8 nrPDB 319 8e-88 6HV7-H nrPDB 306 8e-84 6HUB-H nrPDB 279 6e-76 3UNH-H nrPDB 267 4e-72 6AVO-B nrPDB 263 7e-71 5FMG-I nrPDB 251 3e-67 6EPC-1 nrPDB 216 1e-56 5GJQ-a nrPDB 215 2e-56 6EPF-5 nrPDB 214 3e-56 6AVO-C nrPDB 212 1e-55 5L5A-K nrPDB 210 4e-55 5L64-K nrPDB 209 9e-55 5LN3-5 nrPDB 209 1e-54 3UNF-K nrPDB 208 2e-54 3NZW-K nrPDB 206 9e-54 3UNB-K nrPDB 203 7e-53 5LEZ-N nrPDB 202 1e-52 5CZ8-K nrPDB 199 8e-52 3H4P-A nrPDB 193 8e-50 5FMG-L nrPDB 192 9e-50 5MPC-h nrPDB 187 6e-48 3IPM-H nrPDB 183 8e-47 3H4P-a nrPDB 183 9e-47 6AVO-A nrPDB 182 9e-47 5FMG-E nrPDB 182 1e-46 5GJR-F nrPDB 179 1e-45 6HEC-1 nrPDB 177 4e-45 5FMG-C nrPDB 173 8e-44 3UNF-N nrPDB 172 2e-43 6HE5-A nrPDB 169 2e-42 2Z5C-C nrPDB 159 9e-40 2KU2-A nrPDB 157 3e-39 1G0U-D nrPDB 157 5e-39 6J30-C nrPDB 154 3e-38 4FZC-A nrPDB 154 3e-38 3NZW-E nrPDB 152 1e-37 5LEZ-C nrPDB 151 3e-37 5FMG-N nrPDB 151 3e-37 5FMG-M nrPDB 150 8e-37 5FMG-B nrPDB 149 9e-37 5FGE-J nrPDB 149 1e-36 3WXR-K nrPDB 148 2e-36 6GOP-M nrPDB 146 7e-36 5FMG-K nrPDB 145 2e-35 6FVW-g nrPDB 143 7e-35 5FMG-H nrPDB 143 9e-35 5FGG-F nrPDB 142 1e-34 5LF3-J nrPDB 138 2e-33 2JAY-A nrPDB 132 1e-31 1Q5R-H nrPDB 131 3e-31 1Q5Q-H nrPDB 130 8e-31 5LZP-A nrPDB 126 1e-29 5GJQ-g nrPDB 123 7e-29 5LF6-M nrPDB 122 2e-28 6EPE-7 nrPDB 119 1e-27 5NYF-A nrPDB 95 2e-20 5JI2-A nrPDB 70 9e-13 Sequences not found previously or not previously below threshold: 5LE5-B nrPDB 140 8e-34 5LF0-A nrPDB 134 4e-32 4YA5-C nrPDB 133 6e-32 5FMG-D nrPDB 131 4e-31 5T0I-L nrPDB 124 3e-29 5L4G-U nrPDB 124 4e-29 5VFT-S nrPDB 123 7e-29 6EPF-6 nrPDB 120 5e-28 5FMG-F nrPDB 114 4e-26 3UNE-I nrPDB 109 1e-24 3NZW-L nrPDB 106 1e-23 6EPD-G nrPDB 105 2e-23 4Y8P-I nrPDB 97 5e-21 1IRU-A nrPDB 97 9e-21 5FMG-J nrPDB 87 9e-18 5LOY-A nrPDB 84 6e-17 5FMG-G nrPDB 73 1e-13 5FMG-A nrPDB 71 5e-13 5NYW-A nrPDB 70 1e-12 5LOX-A nrPDB 69 1e-12 4HO7-A nrPDB 67 1e-11 5L5W-G nrPDB 64 6e-11 1OFH-G nrPDB 63 1e-10 1Q5Q-A nrPDB 56 1e-08 1M4Y-A nrPDB 52 2e-07 2Z3B-A nrPDB 51 5e-07 5OVU-A nrPDB 49 2e-06 3TY6-A nrPDB 47 6e-06 1HH2-P nrPDB 33 0.12 3ISH-A nrPDB 31 0.39 5UQG-A nrPDB 31 0.51 1RFZ-A nrPDB 30 1.1 5WKP-D nrPDB 30 1.3 5KZ5-a nrPDB 30 1.4 1WFZ-A nrPDB 30 1.5 4QUR-A nrPDB 29 2.4 1OGQ-A nrPDB 29 2.4 2EEP-A nrPDB 29 2.6 4ZFL-A nrPDB 28 5.2 4V8R-AG nrPDB 27 8.0 5GW5-g nrPDB 27 8.4 >5FGI-H nrPDB Length = 244 Score = 340 bits (872), Expect = 4e-94, Method: Composition-based stats. Identities = 243/244 (99%), Positives = 243/244 (99%) Query: 18 NSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT 77 NSHTQPKATSTG TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT Sbjct: 1 NSHTQPKATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGT 60 Query: 78 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS 137 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS Sbjct: 61 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGS 120 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG Sbjct: 121 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 180 Query: 198 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV 257 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV Sbjct: 181 SGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQV 240 Query: 258 DITA 261 DITA Sbjct: 241 DITA 244 >6EPF-2 nrPDB Length = 277 Score = 324 bits (831), Expect = 2e-89, Method: Composition-based stats. Identities = 145/262 (55%), Positives = 190/262 (72%), Gaps = 6/262 (2%) Query: 1 MAGLSFDNYQRNNFL----AENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVA 56 + G SFDN +RN L A+ PKA TGTTI GV + +G+V+ ADTR+T+G +VA Sbjct: 11 VGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVA 70 Query: 57 DKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHL 116 DKNC+K+H ISP I+C GAGTAADT+ TQLI SN+ELHSL T R PRVV+A +MLKQ L Sbjct: 71 DKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQML 130 Query: 117 FKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLT 176 F+YQG+IGA L++ GVD TG HL+SI+ HGSTD Y+++GSGSLAAMAV E ++ D+ Sbjct: 131 FRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME 190 Query: 177 KEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPR 236 +EEA KL S+AI AGI+NDLGSGSN+D+CV+ K ++LR Y PN + + Y+ + Sbjct: 191 EEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISKSK-LDFLRPYSVPNKKGTRFGRYRCEK 249 Query: 237 GTTAVLKESIVNI-CDIQEEQV 257 GTTAVL E + + ++ EE V Sbjct: 250 GTTAVLTEKVTPLELEVLEEIV 271 >5L4G-8 nrPDB Length = 277 Score = 319 bits (817), Expect = 8e-88, Method: Composition-based stats. Identities = 144/262 (54%), Positives = 189/262 (72%), Gaps = 6/262 (2%) Query: 1 MAGLSFDNYQRNNFL----AENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVA 56 + G SFDN +RN L A+ + PK TGTTI GV + +G+V+ ADTR+T+G +VA Sbjct: 11 VGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVA 70 Query: 57 DKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHL 116 DKNC+K+H ISP I+C GAGTAADT+ TQLI SN+ELHSL T R PRVV+A +MLKQ L Sbjct: 71 DKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQML 130 Query: 117 FKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLT 176 F+YQG+IGA L++ GVD TG HL+SI+ HGSTD Y+++GSGSLAAMAV E ++ D+ Sbjct: 131 FRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME 190 Query: 177 KEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPR 236 +EEA L S+AI AGI+NDLGSGSN+D+CV+ K ++LR Y PN + + Y+ + Sbjct: 191 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK-LDFLRPYTVPNKKGTRLGRYRCEK 249 Query: 237 GTTAVLKESIVNI-CDIQEEQV 257 GTTAVL E I + ++ EE V Sbjct: 250 GTTAVLTEKITPLEIEVLEETV 271 >6HV7-H nrPDB Length = 226 Score = 306 bits (783), Expect = 8e-84, Method: Composition-based stats. Identities = 204/226 (90%), Positives = 214/226 (94%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AAD EAVTQLIG Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI Sbjct: 121 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 255 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE Sbjct: 181 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 226 >6HUB-H nrPDB Length = 234 Score = 279 bits (715), Expect = 6e-76, Method: Composition-based stats. Identities = 130/229 (56%), Positives = 171/229 (74%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI GV + +G+V+ ADTR+T+G +VADKNC+K+H ISP I+C GAGTAADT+ TQLI Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 SN+ELHSL T R PRVV+A +MLKQ LF+YQG+IGA L++ GVD TG HL+SI+ HGSTD Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTD 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 Y+++GSGSLAAMAV E ++ D+ +EEA L S+AI AGI+NDLGSG N+D+CV+ Sbjct: 121 KLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLCVISK 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 K ++LR Y PN + + Y+ +GTTAVL E I + ++ EE V Sbjct: 181 NK-LDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETV 228 >3UNH-H nrPDB Length = 234 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 108/229 (47%), Positives = 151/229 (65%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AADTE T++ Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 S +ELH+L T REPRV + ++L+Q LF+YQGH+GA L+V GVD G L+ +H HGS Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYS 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + +LGSG AA+A+LE ++ ++T E A +L +AI AGI +DLGSG NVD CV+ Sbjct: 121 RLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITA 180 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 G A+ R TP ++ Y+F GTT VL + + ++ EE V Sbjct: 181 G-GAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETV 228 >6AVO-B nrPDB Length = 234 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 109/229 (47%), Positives = 152/229 (66%), Gaps = 2/229 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ F +GV++ ADTR+T +VADK+C K+H I+PKI+C GAG AAD E T+++ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 S +ELH+L T REPRV + ++L+Q LF+YQGH+GA LIV GVD TG L+ +H HGS Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYS 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + +LGSG AA+AVLE ++ ++T E A L +A+ AGI DLGSG NVD CV+ Sbjct: 121 RLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVI-T 179 Query: 210 GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNI-CDIQEEQV 257 A+ LR +P ++ Y F GTTAVL +++ + ++ EE V Sbjct: 180 KTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETV 228 >5FMG-I nrPDB Length = 229 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 107/218 (49%), Positives = 143/218 (65%), Gaps = 2/218 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI G+ N V++ ADTR+T+GPIVADKNC+KLH IS IWCAGAG A D E T + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD 149 N+ELH L T+ +PRV + L Q LFKYQG+ +++ GVD G L+ IH HGS+ Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVLGGVDVNGPQLYGIHPHGSSC 120 Query: 150 VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI 209 + + +LGSGSL AMAVLE+ ++ ++T EE L +AI AGI+NDLGSG NVD+CV+ Sbjct: 121 LLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICVITK 180 Query: 210 GKDAEYLRNYLTPNVR-EEKQKSYKFPRGTTAVLKESI 246 +++R Y PN+R +P+GTT +L E I Sbjct: 181 DS-YQHIRPYKEPNMRLYHLPHPTIYPKGTTPILSEKI 217 >6EPC-1 nrPDB Length = 238 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 56/190 (29%), Positives = 106/190 (55%), Gaps = 1/190 (0%) Query: 22 QPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADT 81 + + STGTTI+ V+F+ GVV+ AD+R+T G +A++ KL I I+C +G+AADT Sbjct: 26 ENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADT 85 Query: 82 EAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDP-TGSHLF 140 +AV + + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++ Sbjct: 86 QAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVY 145 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGS 200 S+ G + GSGS +++ +++ +TK+E ++ ++A+ + D SG Sbjct: 146 SVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGG 205 Query: 201 NVDVCVMEIG 210 + + ++ Sbjct: 206 VIRLAAIQQS 215 >5GJQ-a nrPDB Length = 239 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 57/187 (30%), Positives = 106/187 (56%), Gaps = 1/187 (0%) Query: 22 QPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADT 81 + + STGTTI+ V+F+ GVV+ AD+R+T G +A++ KL I +I+C +G+AADT Sbjct: 27 ESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADT 86 Query: 82 EAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDP-TGSHLF 140 +AV + + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++ Sbjct: 87 QAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVY 146 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGS 200 S+ G + GSGS +++ +++ +TKEE ++ ++A+ + D SG Sbjct: 147 SVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGG 206 Query: 201 NVDVCVM 207 + + + Sbjct: 207 VIRLAAI 213 >6EPF-5 nrPDB Length = 263 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 1/181 (0%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + KF +GV++AAD+R+T GP +A + K+ I+P + AG AAD +L+ Sbjct: 59 GTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGS 147 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 207 G S+GSGS+ A V++ + DL EEA LA AI + D SG V++ + Sbjct: 179 RISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNLYHV 238 Query: 208 E 208 Sbjct: 239 R 239 >6AVO-C nrPDB Length = 204 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 1/180 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV+ A D+R++ G ++ K+ I+P + +G AAD + +L+ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGST 148 L+ L V +A ++L + +Y+G + ++ G D G L+ + HG+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S GSG+ A V++S ++ +L+ EEA L AI D SG V++ M+ Sbjct: 121 LSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMK 180 >5L5A-K nrPDB Length = 211 Score = 210 bits (535), Expect = 4e-55, Method: Composition-based stats. Identities = 52/180 (28%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV+ A D+R++ G ++ K+ I+P + +G AAD + L+ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGST 148 L+ L V +A ++L + +Y+G + ++ G D G L+ + HG+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S GSG+ A VL+S++K DL+ E+A+ L +I A D SG +V++ + Sbjct: 121 LSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVT 180 >5L64-K nrPDB Length = 211 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 55/180 (30%), Positives = 97/180 (53%), Gaps = 1/180 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGST 148 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S+GSGS+ A VL+S++K DL+ E+A+ L +I A D SG +V++ + Sbjct: 121 ISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVT 180 >5LN3-5 nrPDB Length = 263 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 54/181 (29%), Positives = 93/181 (51%), Gaps = 1/181 (0%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 59 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGS 147 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 207 G S+GSGS+ A V++ + DL E+A LA AI + D SG V++ + Sbjct: 179 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHV 238 Query: 208 E 208 Sbjct: 239 R 239 >3UNF-K nrPDB Length = 204 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 53/180 (29%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++A D+R+T G ++ K+ I+P + +G AAD + +L+ Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGST 148 L+ L V +A ++L + +Y+G + ++ G D G L+ + +G+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGTR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S GSG+ A V++S ++QDL+ EEA L AI D SG V++ M+ Sbjct: 121 LSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYHMK 180 >3NZW-K nrPDB Length = 287 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 53/185 (28%), Positives = 94/185 (50%), Gaps = 2/185 (1%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 + GTT + +F G+++A D+R+T G VA + K+ I+P + AG AAD + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGV-DPTGSHLFSIH 143 +GS LH L V +A ++L +++Y+G + ++ G G ++ + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 + G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V+ Sbjct: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 Query: 204 VCVME 208 + + Sbjct: 252 LYHVT 256 >3UNB-K nrPDB Length = 205 Score = 203 bits (516), Expect = 7e-53, Method: Composition-based stats. Identities = 54/180 (30%), Positives = 92/180 (51%), Gaps = 1/180 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +GV++AAD+R+T G +A + K+ I+P + AG AAD +L+ Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHAHGST 148 ++ L V +A ++L +++Y+G + ++ G D G L+ + + G+ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNR 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S+GSGS+ A V++ + DL EEA LA AI + D SG V++ + Sbjct: 121 ISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHVR 180 >5LEZ-N nrPDB Length = 205 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 54/179 (30%), Positives = 101/179 (56%), Gaps = 1/179 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ AD+R+T G +A++ KL I +I+C +G+AADT+AV + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDP-TGSHLFSIHAHGST 148 + HS+ + P V +A + K+ ++Y+ + A +I+AG DP G ++S+ G Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMM 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 207 + GSGS +++ +++ +TKEE ++ ++A+ + D SG + + + Sbjct: 121 VRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAI 179 >5CZ8-K nrPDB Length = 221 Score = 199 bits (507), Expect = 8e-52, Method: Composition-based stats. Identities = 52/185 (28%), Positives = 93/185 (50%), Gaps = 2/185 (1%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 + GTT + +F G+++A D+R+T G VA + + I+P + AG AAD + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGV-DPTGSHLFSIH 143 +GS LH L V +A ++L +++Y+G + ++ G G ++ + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 125 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 + G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V+ Sbjct: 126 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 185 Query: 204 VCVME 208 + + Sbjct: 186 LYHVT 190 >3H4P-A nrPDB Length = 264 Score = 193 bits (490), Expect = 8e-50, Method: Composition-based stats. Identities = 53/199 (26%), Positives = 96/199 (48%), Gaps = 9/199 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A GTT +G+ +GVV+A D R T +V ++ K+ +I + A +G AD Sbjct: 33 EAVRRGTTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARV 91 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQML---KQHLFKYQG--HIGAYLIVAGVDPTGSH 138 + +++ L E + + + KQ ++ G G L++AG+D + Sbjct: 92 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 151 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGS 198 LF G+ ++GSG M +LE ++ D+T +E ++LA A+ N+ Sbjct: 152 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 209 Query: 199 GSNVDVCVMEIGKDAEYLR 217 NVDVC++ + KDA++ + Sbjct: 210 PENVDVCIITV-KDAQFKK 227 >5FMG-L nrPDB Length = 211 Score = 192 bits (489), Expect = 9e-50, Method: Composition-based stats. Identities = 55/182 (30%), Positives = 100/182 (54%), Gaps = 1/182 (0%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT + KF +G+++A D+R++ G ++ +N K+ I+ I AG AAD + +G Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDPTGSHLFSIHAHGST 148 I+++ L + + V +A +L L++Y+G+ + +I++G D TG ++F + G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKK 120 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 G S GSGS A ++L+S + +L ++A++LA +AI + D GSG V V + Sbjct: 121 VEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHIH 180 Query: 209 IG 210 Sbjct: 181 KN 182 >5MPC-h nrPDB Length = 215 Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 54/185 (29%), Positives = 101/185 (54%), Gaps = 2/185 (1%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 S GT+I+ V F +GV++ AD+R+T G +A++ KL R+ KIWC +G+AADT+A+ Sbjct: 15 EVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAI 74 Query: 85 TQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGV-DPTGSHLFSIH 143 ++ ++EL++ P +A + K+ ++ + ++ A +IVAG D +++I Sbjct: 75 ADIVQYHLELYTSQYGT-PSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIP 133 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 GS Y GSGS + +++++++KEE + ++ I D SG + Sbjct: 134 LGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIR 193 Query: 204 VCVME 208 + V+ Sbjct: 194 MVVLT 198 >3IPM-H nrPDB Length = 217 Score = 183 bits (464), Expect = 8e-47, Method: Composition-based stats. Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 2/190 (1%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 + TGTT VG+ + V++A + R T + KN KL +I AG D + Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSHLFSI 142 + + + + +EL+ L + + +L L + + L+V G+D T H+FSI Sbjct: 63 LVRYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGID-TAPHVFSI 121 Query: 143 HAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNV 202 A G + Y S GSGS VLES + + +T +E + L AI A D SG + Sbjct: 122 DAAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMI 181 Query: 203 DVCVMEIGKD 212 DV V+ Sbjct: 182 DVAVITRKDG 191 >3H4P-a nrPDB Length = 219 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 55/183 (30%), Positives = 99/183 (54%), Gaps = 3/183 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT VG+ ++ V++A D R++ G +VADK KL++I I AG+ D +A+ +L+ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVD-PTGSHLFSIHAHGS 147 + +L+ + T R ++ +L L + +I+ G D G+ LFS+ G Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 121 Query: 148 TDVGY-YLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCV 206 + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ + + V Sbjct: 122 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 181 Query: 207 MEI 209 + Sbjct: 182 ITK 184 >6AVO-A nrPDB Length = 199 Score = 182 bits (463), Expect = 9e-47, Method: Composition-based stats. Identities = 52/180 (28%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ +D+R + G V ++ KL + +I+CA +G+AAD +AV + Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSIHAHGST 148 +ELH + P V++A +++ +KY+ + A+L+VAG D G ++ G Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT-LGGML 119 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 + GSGS +++ +K ++ EE + +DAI + D SG + + + Sbjct: 120 TRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTIT 179 >5FMG-E nrPDB Length = 256 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 48/206 (23%), Positives = 89/206 (43%), Gaps = 14/206 (6%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 A G+T VG+ N+GV++A++ R + ++ + KL I I CA +G AD + Sbjct: 30 AIKLGSTAVGICVNDGVILASERRISS-TLIEKDSVEKLLSIDDHIGCAMSGLMADARTL 88 Query: 85 TQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG------------HIGAYLIVAGV 132 + + + S ++++ + + G L++ GV Sbjct: 89 IDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGV 148 Query: 133 DPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGI 192 D G L+ G+ S+GS A +L+ ++K+D+T E+A LA ++ + Sbjct: 149 DKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVM 208 Query: 193 WNDLGSGSNVDVCVMEIGKDAEYLRN 218 D S SNV++C ++ Y N Sbjct: 209 E-DKLSTSNVEICAIKKSDQTFYKYN 233 >5GJR-F nrPDB Length = 241 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G++ + GV +A + R T P++ + K+ I I CA +G AD + Sbjct: 29 EAIKLGSTAIGIQTSEGVCLAVEKRITS-PLMEPSSIEKIVEIDAHIGCAMSGLIADAKT 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG----------HIGAYLIVAGVD 133 + + H + V S Q + ++ G L+ GVD Sbjct: 88 LIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVD 147 Query: 134 PTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIW 193 G LF + G+ ++GS S A + L+ + + +T +EAIK +S I + Sbjct: 148 EKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIK-SSLIILKQVM 206 Query: 194 NDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREE 227 + + +N+++ ++ G++ V ++ Sbjct: 207 EEKLNATNIELATVQPGQNFHMFTKEELEEVIKD 240 >6HEC-1 nrPDB Length = 202 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 55/206 (26%), Positives = 104/206 (50%), Gaps = 7/206 (3%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TT VG+ +GVV+A + R+T G +A K K+++I+ ++ AG+ D + + ++I Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG-HIGAYLIVAGVDPTGSHLFSIHA-HGS 147 L+ + R+P V + + L Y+ L++ G+D G ++SI G+ Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGIDSEGKSIYSIDPIGGA 120 Query: 148 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 207 + ++ GSGSL A VLE + ++ +EA++LA AI + + D SG +DV + Sbjct: 121 IEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVKI 180 Query: 208 EIGKDAEYLRNYLTPNVREEKQKSYK 233 + E+ + +P E+ ++ Sbjct: 181 ---TEDEFYQ--YSPEEVEQILAKFR 201 >5FMG-C nrPDB Length = 246 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 55/216 (25%), Positives = 95/216 (43%), Gaps = 9/216 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A + + +G+ +GV++ AD I N K+++I I+C AG AD Sbjct: 26 EAINNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANI 85 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQM----LKQHLFKYQG--HIGAYLIVAGVD-PTG 136 + + + LY E + VS L + +KQ +Y G G ++ G D G Sbjct: 86 LINQSRLYAQRY-LYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDG 144 Query: 137 SHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDL 196 L+ G+ + ++G+ +L A +VL+ WK D+T EE + LA + ++ Sbjct: 145 YQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEI 204 Query: 197 GSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSY 232 +++ + KD E + YLT EE K Y Sbjct: 205 PKSEKIELAYL-TNKDGEVYQKYLTEKEIEELIKLY 239 >3UNF-N nrPDB Length = 199 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 54/180 (30%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTI+ V+F+ GVV+ +D+R + G V ++ KL + +I+CA +G+AAD +A+ + Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPT-GSHLFSIHAHGST 148 +ELH L P V++A ++K +KY+ + A+LIVAG D G ++ G Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYGT-MGGML 119 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVME 208 + GSGS +++ +K +T EE + ++AI + D SG + + + Sbjct: 120 IRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVTIT 179 >6HE5-A nrPDB Length = 247 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 8/191 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G T +G+K GV++ AD R + A K+++I I A +G AD Sbjct: 30 EAVKRGATAIGIKCKEGVILIADKRVGSKLLEA-DTIEKIYKIDEHICAATSGLVADARV 88 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQML---KQHLFKYQG--HIGAYLIVAGVDPTGSH 138 + +++ L V + + KQ +Y G G L++AGVD Sbjct: 89 LIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV-PK 147 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGS 198 L+ G+ ++G G A E ++ DL+ ++A+ L A+ I ++L Sbjct: 148 LYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESEL-V 206 Query: 199 GSNVDVCVMEI 209 N++V +++ Sbjct: 207 PENIEVGYVKV 217 >2Z5C-C nrPDB Length = 262 Score = 159 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 50/217 (23%), Positives = 88/217 (40%), Gaps = 14/217 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+ GVV+ + R+T P++ + K+ I I CA +G AD + Sbjct: 31 EAIKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARS 89 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-----------HIGAYLIVAGV 132 + + + H+LY + V S Q + ++ G L++AG Sbjct: 90 MIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGH 149 Query: 133 D-PTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 191 D G LF G+ ++GSGS A A L + W LT +EA L ++ Sbjct: 150 DADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQV 209 Query: 192 IWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEK 228 + + +N + + + N T + +E Sbjct: 210 ME-EKLDENNAQLSCITKQDGFKIYDNEKTAELIKEL 245 >2KU2-A nrPDB Length = 237 Score = 157 bits (398), Expect = 3e-39, Method: Composition-based stats. Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 6/176 (3%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+KF NGV++ +D + + ++ + K+ I + +G AD Sbjct: 33 EAVKKGSTALGMKFANGVLLISDKKV-RSRLIEQNSIEKIQLIDDYVAAVTSGLVADARV 91 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-----HIGAYLIVAGVDPTGSH 138 + + + + + + ++ + + +Y G LI AG+D G Sbjct: 92 LVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQIGPR 151 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWN 194 LF G+ + ++GSG A ++ LE +K++L ++EA+ L A+++ + Sbjct: 152 LFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLEE 207 >1G0U-D nrPDB Length = 241 Score = 157 bits (396), Expect = 5e-39, Method: Composition-based stats. Identities = 50/208 (24%), Positives = 86/208 (41%), Gaps = 5/208 (2%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T +G+ GVV+ + R+T P++ + K+ I I CA +G AD + Sbjct: 29 EAIKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARS 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY--QGHIGAYLIVAGVD-PTGSHLF 140 + + + H+LY + V S Q + G L++AG D G LF Sbjct: 88 MIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMSRPFGVALLIAGHDADDGYQLF 147 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGS 200 G+ ++GSGS A A L + W LT +EA L ++ + + + Sbjct: 148 HAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVME-EKLDEN 206 Query: 201 NVDVCVMEIGKDAEYLRNYLTPNVREEK 228 N + + + N T + +E Sbjct: 207 NAQLSCITKQDGFKIYDNEKTAELIKEL 234 >6J30-C nrPDB Length = 258 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 48/211 (22%), Positives = 97/211 (45%), Gaps = 7/211 (3%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 ++ S T +G+ ++G+V+AA+ + T + D + KL++++ KI A AG AD E Sbjct: 27 ESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEI 86 Query: 84 VTQLIGSNIELHSLYTSREPRV---VSALQMLKQHLFKYQG--HIGAYLIVAGVDPT-GS 137 + + + + + + V V L +KQ ++ G G I AG D G Sbjct: 87 LINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGY 146 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 L++ + G+ +S+G+ + AA +L+ +K D+ ++AI+LA + + Sbjct: 147 QLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSAL 206 Query: 198 SGSNVDVCVMEIGK-DAEYLRNYLTPNVREE 227 + ++ + G D E + P ++ Sbjct: 207 TYDRLEFATIRKGANDGEVYQKIFKPQEIKD 237 >4FZC-A nrPDB Length = 250 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 47/190 (24%), Positives = 86/190 (45%), Gaps = 9/190 (4%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 A G T +G+K NGVVIA + +S+ P+ + +K+ ++P I +G D + Sbjct: 27 AVKQGVTSLGIKATNGVVIATEKKSSS-PLAMSETLSKVSLLTPDIGAVYSGMGPDYRVL 85 Query: 85 TQLIGS--NIELHSLYTSREP--RVVSALQMLKQHLFKYQG--HIGAYLIVAGVDP-TGS 137 + +Y P +VS + + Q + G G L++AG D G Sbjct: 86 VDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGF 145 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 L+ + GS ++G GS+AA LE W +L E+AI +A ++ + + Sbjct: 146 SLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGE-F 204 Query: 198 SGSNVDVCVM 207 +G +++ ++ Sbjct: 205 NGDTIELAII 214 >3NZW-E nrPDB Length = 234 Score = 152 bits (384), Expect = 1e-37, Method: Composition-based stats. Identities = 48/201 (23%), Positives = 83/201 (41%), Gaps = 14/201 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+ VG++ N V+ A R+ K K+ + + + AG A D Sbjct: 27 EAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQK---KIIKCDEHMGLSLAGLAPDARV 83 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFK----YQG-HIGAYLIVAGVDPTGSH 138 ++ + SL +R+ V A +L K Y G G L++ G D +G+H Sbjct: 84 LSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAH 143 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLES----HWKQDLTKEEAIKLASDAIQAGIWN 194 L G+ Y ++G+ S A LE K D +E IK +AI + + Sbjct: 144 LLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRD 203 Query: 195 DLGSGSNVDVCVMEIGKDAEY 215 + + N+ + + +GKD + Sbjct: 204 ESLTVDNLSIAI--VGKDTPF 222 >5LEZ-C nrPDB Length = 248 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 45/212 (21%), Positives = 80/212 (37%), Gaps = 20/212 (9%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+T VGV+ + VV+ + +S + ++ K+ + + A AG AD Sbjct: 24 EAVKKGSTAVGVRGRDIVVLGVEKKSVAK-LQDERTVRKICALDDNVCMAFAGLTADARI 82 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQM---LKQHLFKYQG--HIGAYLIVAGVDPTG-S 137 V + H L V + LKQ + G G ++ G D G Sbjct: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHW------KQDLTKEEAIKLASDAIQAG 191 L+ G+ ++G G+ + LE ++ DLT + IK + +Q+G Sbjct: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSG 202 Query: 192 IWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPN 223 G N+++ VM + + L Sbjct: 203 -------GKNIELAVMRRDQSLKILNPEEIEK 227 >5FMG-N nrPDB Length = 265 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 52/253 (20%), Positives = 100/253 (39%), Gaps = 47/253 (18%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 TGT+++ +K+ +G++IAAD +++ G +N ++ +I+ K +G AD + + Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 86 QLIGSNIELHSL--------------YTSREPRVVSALQMLKQHLF-----------KYQ 120 +L+ +++L Y S RV + LF KY Sbjct: 66 ELLTRK-NINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYD 124 Query: 121 GHIGAYLIVAG------------------VDPTGSHLFSIHAHGSTDVGYYLSLGSGSLA 162 + L+ + ++ + HG+ Y++ G Sbjct: 125 NNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYF 184 Query: 163 AMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTP 222 A+ +L H+K ++T+EEA L ++ ++ + D + SN V K EY Y+ P Sbjct: 185 ALTLLRDHYKDNMTEEEARILINECLRILYFRD-ATSSNFIQIVKVTSKGVEYEEPYILP 243 Query: 223 NVREEKQKSYKFP 235 V Y +P Sbjct: 244 CVLN--SADYVYP 254 >5FMG-M nrPDB Length = 240 Score = 150 bits (378), Expect = 8e-37, Method: Composition-based stats. Identities = 44/194 (22%), Positives = 88/194 (45%), Gaps = 10/194 (5%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 G T++G+ + V++AADTR + + + C K+ +++ K +G +D + + Sbjct: 34 IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLH 93 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSH-LFSIH 143 L+ I+L L S P + ++L L+ + A+ I+AGVD L++ Sbjct: 94 SLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYD 153 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQ--------DLTKEEAIKLASDAIQAGIWND 195 + GS + +GSGS + +L++ +Q + + I DAI + D Sbjct: 154 SVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERD 213 Query: 196 LGSGSNVDVCVMEI 209 + +G + V++ Sbjct: 214 IYTGDKTLIYVIDK 227 >5FMG-B nrPDB Length = 235 Score = 149 bits (377), Expect = 9e-37, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 7/191 (3%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 S+ + +G++ NGV+IA + +S ++ + + K+ +IS I AG D + Sbjct: 29 VSSSSPALGIRAKNGVIIATEKKSPNE-LIEENSIFKIQQISEHIGIVYAGMPGDFRVLL 87 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-----HIGAYLIVAGVDPTGSHLF 140 + +SL E V ++++ + ++ G L++ GVD G HL+ Sbjct: 88 KRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVYGYHLY 147 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGS 200 I G +G M+ LE + +D+ E+AI A ++ + + Sbjct: 148 QIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYEG-VLNEK 206 Query: 201 NVDVCVMEIGK 211 N+++ V K Sbjct: 207 NIEIGVAYDNK 217 >5FGE-J nrPDB Length = 198 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 5/168 (2%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I +N Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 92 IELHSLYTSREPRVVSALQMLKQHL---FKYQGHIGAYLIVAGVD--PTGSHLFSIHAHG 146 I+L+S+ E + ++Q L + + +++ G D L+ I G Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWN 194 + Y + G ++L+ H++ D+T EE + L +Q Sbjct: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKR 171 >3WXR-K nrPDB Length = 238 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 5/168 (2%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I +N Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 92 IELHSLYTSREPRVVSALQMLKQHL---FKYQGHIGAYLIVAGVD--PTGSHLFSIHAHG 146 I+L+S+ E + ++Q L + + +++ G D L+ I G Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWN 194 + Y + G ++L+ H++ D+T EE + L +Q Sbjct: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKR 171 >6GOP-M nrPDB Length = 246 Score = 146 bits (369), Expect = 7e-36, Method: Composition-based stats. Identities = 41/222 (18%), Positives = 89/222 (40%), Gaps = 14/222 (6%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 TGT+++ +K++NGV+IAAD + G ++ +L + +G +D + + Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 86 QLIGSNIELHSLYT-----SREPRVVSALQMLKQHLFKYQGHIGA---YLIVAGVDPTGS 137 +L+ + ++ + L +++ + + +IVAGV G Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQSNGD 137 Query: 138 H-LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWK-----QDLTKEEAIKLASDAIQAG 191 L ++ G T L+ G G+ A +L T + A + +A++ Sbjct: 138 QFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRVL 197 Query: 192 IWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYK 233 + D S N + +++ + +N N++ + K K Sbjct: 198 YYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIK 239 >5FMG-K nrPDB Length = 195 Score = 145 bits (365), Expect = 2e-35, Method: Composition-based stats. Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 4/185 (2%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPI-VADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 T++G++ NN VV+AADT S I + + + K + I G+ D + I Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 90 SNIELHSLYTSREPRVVSALQMLKQHLFKY--QGHIGAYLIVAGVDPT-GSHLFSIHAHG 146 N+ L+ + + V S +++L Y + ++AG D G L+ Sbjct: 63 KNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLS 122 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCV 206 + D + G G+ A+L+ ++ ++LT +EA+ + + L + N ++ + Sbjct: 123 NMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINYELRI 182 Query: 207 MEIGK 211 M K Sbjct: 183 MYDNK 187 >6FVW-g nrPDB Length = 245 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 47/181 (25%), Positives = 71/181 (39%), Gaps = 9/181 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 KA GTT +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 26 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 84 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQH-----LFKYQGHIGAYLIVAGVDPTGSH 138 + + + L Q+ L+ G I GVD G+H Sbjct: 85 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 144 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLES---HWKQDLTKEEAIKLASDAIQAGIWND 195 L+ + GS + G G +A A LE H + L+ EA+K A+ I ++ Sbjct: 145 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 204 Query: 196 L 196 Sbjct: 205 K 205 >5FMG-H nrPDB Length = 252 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 55/241 (22%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI- 88 TTI+G+ ++NGV++A D+R++ G +++K K++RI+ ++ +G +A ++ + ++I Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 89 ----------GSNIELHS------------------------------------------ 96 H Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 97 LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDP-TGSHLFSIHAHGSTDVGYYLS 155 + P V + + K+ ++ + LI G D L++++ +GS + + Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDFA 180 Query: 156 L-GSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAE 214 + GSGS+ + L+ +K+ +TK+E L + ++ + ND SG + + + E Sbjct: 181 VSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVEE 240 Query: 215 Y 215 + Sbjct: 241 F 241 >5FGG-F nrPDB Length = 288 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 47/181 (25%), Positives = 71/181 (39%), Gaps = 9/181 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 KA GTT +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQH-----LFKYQGHIGAYLIVAGVDPTGSH 138 + + + L Q+ L+ G I GVD G+H Sbjct: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLES---HWKQDLTKEEAIKLASDAIQAGIWND 195 L+ + GS + G G +A A LE H + L+ EA+K A+ I ++ Sbjct: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 207 Query: 196 L 196 Sbjct: 208 K 208 >5LE5-B nrPDB Length = 261 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 88/201 (43%), Gaps = 7/201 (3%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A T +G+ N+GV++AA+ R+ + K+++++ + C+ AG +D Sbjct: 26 EAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANV 85 Query: 84 VTQLIGSNIELHSLYTSREPR---VVSALQMLKQHLFKYQG--HIGAYLIVAGVDP-TGS 137 +T + + + L +V+AL +KQ ++ G G L+ G D G Sbjct: 86 LTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGF 145 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQD-LTKEEAIKLASDAIQAGIWNDL 196 L+ G+ +G+ S AA+++L+ +K+ +T + A+ LA + + Sbjct: 146 QLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSK 205 Query: 197 GSGSNVDVCVMEIGKDAEYLR 217 S V++ + +R Sbjct: 206 LSAEKVEIATLTRENGKTVIR 226 >5LF3-J nrPDB Length = 201 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 31/184 (16%), Positives = 82/184 (44%), Gaps = 4/184 (2%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGS 90 ++G++ + V++A+D + + + K+ ++S KI G A DT + I Sbjct: 3 YLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQK 62 Query: 91 NIELHSLYTSREPRVVSALQMLKQHL---FKYQGHIGAYLIVAGVDP-TGSHLFSIHAHG 146 N++L+ + E +A +++L + + L++AG D G L+ + Sbjct: 63 NVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLA 122 Query: 147 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCV 206 + + + G G+ +++L+ ++ +++E A++L ++ + + V + Sbjct: 123 ALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRI 182 Query: 207 MEIG 210 ++ Sbjct: 183 IDKN 186 >5LF0-A nrPDB Length = 234 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 73/187 (39%), Gaps = 7/187 (3%) Query: 25 ATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAV 84 A + G VG+K NGVV+A + + + + +++ K+ I+ I +G D + Sbjct: 28 AVAGGAPSVGIKAANGVVLATEKKQ-KSILYDERSVHKVEPITKHIGLVYSGMGPDYRVL 86 Query: 85 TQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-----HIGAYLIVAGVDPTGSHL 139 + + L +Q + + +Y G L++ G + +L Sbjct: 87 VHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGRPYL 146 Query: 140 FSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 F G+ ++G + LE + +DL E+AI A ++ + + Sbjct: 147 FQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQM-TE 205 Query: 200 SNVDVCV 206 N++V + Sbjct: 206 DNIEVGI 212 >4YA5-C nrPDB Length = 254 Score = 133 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 42/199 (21%), Positives = 75/199 (37%), Gaps = 13/199 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A GT VGVK N VV+ + RST +K+ +I + + +G AD+ Sbjct: 25 EAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRI 84 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLK---QHLFKYQG--HIGAYLIVAGVDPTG-- 136 + + + H L V + + Q + G G ++AG DP Sbjct: 85 LIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDE 144 Query: 137 SHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHW---KQDLTKEEAIKLASDAIQAGIW 193 L+ G ++G S LE ++ + T EE +KL ++ + Sbjct: 145 PKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQ 204 Query: 194 NDLGSGSNVDVCVMEIGKD 212 N+++ V++ D Sbjct: 205 T---GAKNIEITVVKPDSD 220 >2JAY-A nrPDB Length = 291 Score = 132 bits (333), Expect = 1e-31, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 18/188 (9%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTTIV +K+ GVV+A D RSTQG +++ ++ K++ AGTAA +L Sbjct: 57 GTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLY 116 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL-------------IVAGVDPT 135 +E + E ++ + + +G++ A + I A + Sbjct: 117 AVELEHYE---KLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQS 173 Query: 136 GSHLFSIHAHGSTD--VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIW 193 + S A G + Y ++GSGSL A + ++ + Q + +++A +A+ Sbjct: 174 AGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAAD 233 Query: 194 NDLGSGSN 201 +D +G Sbjct: 234 DDSATGGP 241 >1Q5R-H nrPDB Length = 294 Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats. Identities = 40/185 (21%), Positives = 75/185 (40%), Gaps = 12/185 (6%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 GTTIV + + GV++A D R+TQG ++A ++ ++ AGTA + +L Sbjct: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRLF 124 Query: 89 GSNIELHSLYTSREPR----VVSALQMLKQHLFKYQGHIGAYLIVAGVD------PTGSH 138 +E + M++ +L + ++ G D Sbjct: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 Query: 139 LFSIHAHGSTDVGY--YLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDL 196 + S G Y ++GSGSL A + L+ + D +E A++ A +++ +D Sbjct: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 Query: 197 GSGSN 201 +G Sbjct: 245 ATGGP 249 >5FMG-D nrPDB Length = 241 Score = 131 bits (329), Expect = 4e-31, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 80/209 (38%), Gaps = 11/209 (5%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G V +K +N V+A + ++ + K KL ++ A AG AD Sbjct: 24 EAVKKGGCAVAIKSSNFAVLAVEKKNIPK-LQNPKTTEKLIKLDEHNCLAFAGLNADARV 82 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLK--QHLFKYQG---HIGAYLIVAGVDPTGS- 137 + + + L V + + Q F ++G G ++AG Sbjct: 83 LVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEI 142 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 ++ G ++G + LE ++++++ +++ I LA AI + Sbjct: 143 CIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVE---L 199 Query: 198 SGSNVDVCVMEIGKDAEYLRNYLTPNVRE 226 S NV+V ++ KD ++ ++ E Sbjct: 200 SSKNVEVALL-TEKDLTFIEEQEINSMVE 227 >1Q5Q-H nrPDB Length = 235 Score = 130 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 12/184 (6%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG 89 TTIV + + GV++A D R+TQG ++A ++ K++ AGTA + +L Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 90 SNIELHSLYTSREPR----VVSALQMLKQHLFKYQGHIGAYLIVAGVD------PTGSHL 139 +E + M++ +L + ++ G D + Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 140 FSIHAHGSTDVGY--YLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 197 S G Y ++GSGSL A + L+ + D +E A++ A +++ +D Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 198 SGSN 201 +G Sbjct: 181 TGGP 184 >5LZP-A nrPDB Length = 242 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 42/186 (22%), Positives = 80/186 (43%), Gaps = 18/186 (9%) Query: 31 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGS 90 TIV +K+ GVV+A D RSTQG +++ ++ K++ AGTAA +L Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 91 NIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL-------------IVAGVDPTGS 137 +E + E ++ + + +G++ A + I A + Sbjct: 62 ELEHYE---KLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 118 Query: 138 HLFSIHAHGSTD--VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWND 195 + S A G + Y ++GSGSL A + ++ + Q + +++A +A+ +D Sbjct: 119 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 178 Query: 196 LGSGSN 201 +G Sbjct: 179 SATGGP 184 >5T0I-L nrPDB Length = 268 Score = 124 bits (312), Expect = 3e-29, Method: Composition-based stats. Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 13/200 (6%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 +A G+ VG+K V+ A R+ K K+ + I + AG AD Sbjct: 32 EAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQK---KILHVDNHIGISIAGLTADARL 88 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQML---KQHLFKYQG--HIGAYLIVAGVDPTGSH 138 + + R V + ++ Q + G G L++AG D G H Sbjct: 89 LCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPH 148 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDL--TKEEAIKLASDAIQAGIWND- 195 +F + +S+G+ S +A LE H + + E +K A++ + + Sbjct: 149 IFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQ 208 Query: 196 LGSGSNVDVCVMEIGKDAEY 215 + NV + + +GKD E+ Sbjct: 209 DLTTKNVSIGI--VGKDLEF 226 >5L4G-U nrPDB Length = 241 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 85/195 (43%), Gaps = 11/195 (5%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 G TI+ + + ++A+DTR ++G + ++ K ++++ K +G D +T Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSH-LFSIH 143 ++I + ++++ ++ + ML L+ + Y I+ G+D G ++S Sbjct: 94 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHW---------KQDLTKEEAIKLASDAIQAGIWN 194 GS + + GS S +L++ L+ + A++L D + Sbjct: 154 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 213 Query: 195 DLGSGSNVDVCVMEI 209 D+ +G + +C++ Sbjct: 214 DVYTGDALRICIVTK 228 >5GJQ-g nrPDB Length = 264 Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats. Identities = 46/213 (21%), Positives = 86/213 (40%), Gaps = 12/213 (5%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 52 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111 Query: 88 IGSNI---ELHSLYTSREPRVVSALQMLKQHLFKYQGHIGA---YLIVAGVDPTGSHLFS 141 +G + EL S PR + L + ++ + + +++ G S L Sbjct: 112 LGQMVIDEELLGDGHSYSPR--AIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGY 169 Query: 142 IHAHGSTDVGYYLSLGSGSLAAMAVLES--HWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 + G L+ G G+ A +L + L++ EA L ++ + D S Sbjct: 170 VDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSY 229 Query: 200 SNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSY 232 + + + K E T + Sbjct: 230 NRFQIATV-TEKGVEIEGPLSTET-NWDIAHMI 260 >5VFT-S nrPDB Length = 213 Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 85/195 (43%), Gaps = 11/195 (5%) Query: 26 TSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVT 85 G TI+ + + ++A+DTR ++G + ++ K ++++ K +G D +T Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 86 QLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSH-LFSIH 143 ++I + ++++ ++ + ML L+ + Y I+ G+D G ++S Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 125 Query: 144 AHGSTDVGYYLSLGSGSLAAMAVLESHW---------KQDLTKEEAIKLASDAIQAGIWN 194 GS + + GS S +L++ L+ + A++L D + Sbjct: 126 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 185 Query: 195 DLGSGSNVDVCVMEI 209 D+ +G + +C++ Sbjct: 186 DVYTGDALRICIVTK 200 >5LF6-M nrPDB Length = 219 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 46/213 (21%), Positives = 86/213 (40%), Gaps = 12/213 (5%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 7 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 66 Query: 88 IGSNI---ELHSLYTSREPRVVSALQMLKQHLFKYQGHIGA---YLIVAGVDPTGSHLFS 141 +G + EL S PR + L + ++ + + +++ G S L Sbjct: 67 LGQMVIDEELLGDGHSYSPR--AIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGY 124 Query: 142 IHAHGSTDVGYYLSLGSGSLAAMAVLES--HWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 + G L+ G G+ A +L + L++ EA L ++ + D S Sbjct: 125 VDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSY 184 Query: 200 SNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSY 232 + + + K E T + Sbjct: 185 NRFQIATV-TEKGVEIEGPLSTET-NWDIAHMI 215 >6EPF-6 nrPDB Length = 240 Score = 120 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 85/193 (44%), Gaps = 11/193 (5%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 G T++ + + ++A+DTR ++G + ++ K ++++ K +G D +T++ Sbjct: 35 NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 94 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSH-LFSIHAH 145 I + ++++ ++ + ML L+ + Y I+ G+D G ++S Sbjct: 95 IEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPV 154 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHW---------KQDLTKEEAIKLASDAIQAGIWNDL 196 GS + + GS S +L++ LT + A++L D + D+ Sbjct: 155 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDV 214 Query: 197 GSGSNVDVCVMEI 209 +G + +C++ Sbjct: 215 YTGDALRICIVTK 227 >6EPE-7 nrPDB Length = 263 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 46/213 (21%), Positives = 86/213 (40%), Gaps = 12/213 (5%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 TGT+++GVKF+ GVVIAAD + G + +N +++ R++ +G AD + + Q+ Sbjct: 51 TGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQV 110 Query: 88 IGSNI---ELHSLYTSREPRVVSALQMLKQHLFKYQGHIGA---YLIVAGVDPTGSHLFS 141 +G + EL S PR + L + ++ + + ++ G S L Sbjct: 111 LGQMVIDEELFGDGHSYSPR--AIHSWLTRAMYSRRSKMNPLWNTKVIGGYAGGESFLGY 168 Query: 142 IHAHGSTDVGYYLSLGSGSLAAMAVLES--HWKQDLTKEEAIKLASDAIQAGIWNDLGSG 199 + G L+ G G+ A +L + L++ EA +L ++ + D S Sbjct: 169 VDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLYYRDARSY 228 Query: 200 SNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSY 232 + V + K E + Sbjct: 229 NRFQVATV-TEKGVEIEGPLSAQT-NWDIAHMI 259 >5FMG-F nrPDB Length = 254 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 78/208 (37%), Gaps = 12/208 (5%) Query: 23 PKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTE 82 +A GT V +K + VV++ + K+ +I I + +G +D + Sbjct: 26 SEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ---EKIFKIDDYIGISMSGITSDAK 82 Query: 83 AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-----IGAYLIVAGVDPTGS 137 +T+ + + H + + S ++ + K G L++A Sbjct: 83 VLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFGVGLMIAAYH-NEP 141 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWK--QDLTKEEAIKLASDAIQAGIWND 195 +F +GS LS G+ S A+ LE + ++ + EE I A++ + ++ Sbjct: 142 CIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECSLEELILHCLKALKCSLSSE 201 Query: 196 L-GSGSNVDVCVMEIGKDAEYLRNYLTP 222 + SN + V+ + + + Sbjct: 202 SELTISNTALAVVGKNHPWQEISSLQLE 229 >3UNE-I nrPDB Length = 205 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 4/188 (2%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 G ++ +K N V IAAD R + + K+ + +++ AG A D + V Q Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHLF-KYQGHIGAYLIVAGVDPT--GSHLFSIHA 144 + + L+ L R+ + + + M+ L+ K G ++AG+DP + S+ Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126 Query: 145 HGS-TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 G ++ G+ S + ES W+ ++ E + S A+ + D SG V Sbjct: 127 IGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI 186 Query: 204 VCVMEIGK 211 V V+E K Sbjct: 187 VHVIEKDK 194 >3NZW-L nrPDB Length = 241 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 40/202 (19%), Positives = 86/202 (42%), Gaps = 20/202 (9%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 G TI+G+ + V+A DTR+ + + K+ I + G AAD +A+ + Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 88 IGSNIE-LHSLYTSREPRVVSALQMLKQHLF-KYQGHIGAYLIVAGVDPTGSH-LFSIHA 144 ++++ H + ++ + SA + ++ L+ K + I+AG+D G ++S Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDP 146 Query: 145 HGSTDVGYYLSLGSGSLAAMAVLE------SHWKQD-----------LTKEEAIKLASDA 187 GS + + G+ + M L+ + ++ L+ EE IKL D+ Sbjct: 147 VGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDS 206 Query: 188 IQAGIWNDLGSGSNVDVCVMEI 209 + + G +++ ++ Sbjct: 207 FTSATERHIQVGDGLEILIVTK 228 >6EPD-G nrPDB Length = 255 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 58/172 (33%), Gaps = 7/172 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83 KA +T +G++ +GVV + N +L + + A AG AD + Sbjct: 29 KAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN-KRLFNVDRHVGMAVAGLLADARS 87 Query: 84 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-----GHIGAYLIVAGVDPT-GS 137 + + + + ++ Y G ++ G+ Sbjct: 88 LADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGA 147 Query: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 189 L+ I G + + ++G AA +E +++T + +K + I Sbjct: 148 QLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIY 199 >4Y8P-I nrPDB Length = 205 Score = 97.4 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 72/197 (36%), Gaps = 8/197 (4%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87 G +V + + V IA D R + K+ ++ G A D + ++ Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFH-YGHVFLGITGLATDVTTLNEM 66 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAGVDPTGSHLF--SIHA 144 L+ L R + Q++ L++ + G +VAG++ F Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDL 126 Query: 145 HGSTDVGYYLSL-GSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 203 G D + G+ S + ES ++ +L E+ + S A+ D SG Sbjct: 127 IGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAV 186 Query: 204 VCVMEIGKDAEYLRNYL 220 V ++ K E ++ YL Sbjct: 187 VYII---KKDEVVKRYL 200 >1IRU-A nrPDB Length = 246 Score = 96.6 bits (239), Expect = 9e-21, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 68/195 (34%), Gaps = 11/195 (5%) Query: 24 KATSTGT-TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTE 82 KA + G T V V+ + VI + + + L +I+ I C G AD+ Sbjct: 30 KAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSS-TVTHLFKITENIGCVMTGMTADSR 88 Query: 83 AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQG-----HIGAYLIVAGVDPT-G 136 + Q E V + + Y +G +I+ G+D G Sbjct: 89 SQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQG 148 Query: 137 SHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQ--DLTKEEAIKLASDAIQAGIWN 194 ++ G + G + + LE K+ D T E+ ++ A + + Sbjct: 149 PQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSI 208 Query: 195 DLGSGSNVDVCVMEI 209 D S ++V V+ + Sbjct: 209 D-FKPSEIEVGVVTV 222 >5NYF-A nrPDB Length = 245 Score = 95.4 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 52/232 (22%), Positives = 92/232 (39%), Gaps = 47/232 (20%) Query: 29 GTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI------SPKIW-CAGAGTAADT 81 GT V + G+V AADTR+ G N A+ ++ +++ AG A T Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGV----DNIAQYKKLQLWRQPGERVFVLLSAGNLAAT 57 Query: 82 EAVTQLIGSNI------ELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYL-------- 127 +AV LI ++ E+ +L+T+ P + A +++ + + + GA L Sbjct: 58 QAVVSLINEHLSQETDDEVTTLFTA--PNMYRAARVVGDAVREARSIDGAALEASKLGFN 115 Query: 128 ---IVAG-VDPTGSHLFSIHAHGSTDVG----YYLSLGSGSLAAMAVLESHWKQDLTKEE 179 I G + LF I+ G+ + +G +L+ + D+ E Sbjct: 116 TNFIFGGQIKGERPRLFQIYPEGNFIEATDDTPFFQIGEHKYG-KPILDRVARSDMRLGE 174 Query: 180 AIKLASDAIQAGIWNDLGSGSNVDVCVME-----------IGKDAEYLRNYL 220 A KL + + + ++L G +D+ + E I D EY RN Sbjct: 175 AAKLMLLSFDSTLRSNLSVGMPIDLVIYERDTFDVTREKRISADDEYFRNLS 226 >5FMG-J nrPDB Length = 218 Score = 86.6 bits (213), Expect = 9e-18, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 74/200 (37%), Gaps = 16/200 (8%) Query: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIV-ADKNCAKLHRISPKIWCAGAGTAADTEAVTQ 86 G ++G+ +N V IA D R +K+ +++ ++ +G A D + + + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 87 LIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQ-GHIGAYLIVAG------VDPTG--- 136 ++ + L+ + E V ML L+ + IV G VD G Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKK 127 Query: 137 ----SHLFSIHAHGSTDVGYYLSL-GSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 191 +L + G+ + G S + ES + +D + + S + + Sbjct: 128 VNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSA 187 Query: 192 IWNDLGSGSNVDVCVMEIGK 211 + D SG +V V+ K Sbjct: 188 LDRDCISGWGAEVLVLTPEK 207 >5LOY-A nrPDB Length = 240 Score = 83.9 bits (206), Expect = 6e-17, Method: Composition-based stats. Identities = 46/222 (20%), Positives = 82/222 (36%), Gaps = 39/222 (17%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRIS-------PKIWCAGAGTAADTE 82 T VG++ + G+V A+D+R+ G N + ++ I AG A T+ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGV----DNISTFRKMHVFEVPGERVIVLLTAGNLATTQ 56 Query: 83 AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTG------ 136 AV L+ ++ P + A +++ + L + Q L GVD Sbjct: 57 AVISLLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGG 116 Query: 137 ------SHLFSIHAHGSTDVG----YYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASD 186 LF I+ G+ + +G +L+ D + E+A K A Sbjct: 117 QIAGEPPRLFLIYPAGNFIEATPDTPFFQIGETKYG-KPILDRVITPDTSLEDAAKCALV 175 Query: 187 AIQAGIWNDLGSGSNVDVCVME-----------IGKDAEYLR 217 + + + ++L G +D+ V E I +D Y R Sbjct: 176 SFDSTMRSNLSVGLPLDLLVYERDSLRVGHRRRIDEDDPYFR 217 >5FMG-G nrPDB Length = 252 Score = 73.1 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 17/166 (10%), Positives = 59/166 (35%), Gaps = 7/166 (4%) Query: 24 KATSTGTTIVGVKFNNGVVIAA-DTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTE 82 K+ + T + ++ +G++ ++ + ++ + +++ ++ I +G D Sbjct: 29 KSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDAR 88 Query: 83 AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY-----QGHIGAYLIVAGVDPTGS 137 + S + + + + ++ Y A +I++ + Sbjct: 89 NIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDK 148 Query: 138 H-LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIK 182 ++ I +G+ + +G +E +D+ +AI+ Sbjct: 149 GDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIE 194 >5FMG-A nrPDB Length = 260 Score = 71.2 bits (173), Expect = 5e-13, Method: Composition-based stats. Identities = 42/208 (20%), Positives = 77/208 (37%), Gaps = 23/208 (11%) Query: 24 KATS-TGTTIVGVKFNNGVVIAADTR-----STQGPIVADKNCAKLHRISPKIWCAGAGT 77 KA T T VGVK N VI + + +Q ++ N ++ I+ +I C+ G Sbjct: 30 KAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGM 89 Query: 78 AADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHI-----GAYLIVAGV 132 D ++ S + + + + Y H ++ G+ Sbjct: 90 PGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMIIGI 149 Query: 133 DPTG-SHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLES---HWKQDL---TKEEAIK--- 182 D LF G +G+ +++VLE K+ + T +E I+ Sbjct: 150 DENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTT 209 Query: 183 -LASDAIQAGIWNDLGSGSNVDVCVMEI 209 LA +A+Q + DL S ++V ++ Sbjct: 210 ILAIEALQTILAFDL-KASEIEVAIVST 236 >5JI2-A nrPDB Length = 184 Score = 70.0 bits (170), Expect = 9e-13, Method: Composition-based stats. Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 9/163 (5%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQLI 88 TTIV V+ N VVIA D ++T G V N K+ R+ + K+ AG AD + +L Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGST 148 +E+H + V A + + + A L VA D T S + + + Sbjct: 62 ERKLEMHQ-GHLVKAAVELAKDWRTDRMLR---KLEALLAVA--DETASLIITGNGDVVQ 115 Query: 149 DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 191 +++GSG A A + + T+ A ++A A+ Sbjct: 116 PENDLIAIGSGGPYAQAAARALLEN--TELSAREIAEKALDIA 156 >5NYW-A nrPDB Length = 251 Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 37/237 (15%), Positives = 89/237 (37%), Gaps = 24/237 (10%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI----SPKIWCAGAGTAADTEAVT 85 T V ++ ++G+ A+D+R+ G + KLH + AG A T+++ Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAG-VDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIV 59 Query: 86 QLIGSNI---------ELHSLYTSREPRVVSALQMLKQHLFKYQG----HIGAYLIVAG- 131 L+ + S+Y + + +++ + Q L++ G Sbjct: 60 SLLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQ 119 Query: 132 VDPTGSHLFSIHAHGSTDVG----YYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDA 187 + G LF I+ G+ Y +G S +++ D ++A++ A + Sbjct: 120 IKGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCALIS 178 Query: 188 IQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKE 244 + + + ++L G +DV + + + + +T + + G ++ + Sbjct: 179 MDSTLRSNLSVGLPLDVMIYPLDSFSTEQQYRITEDHPYFMMIRKGWGEGLVSIFAQ 235 >5LOX-A nrPDB Length = 242 Score = 69.2 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 79/197 (40%), Gaps = 21/197 (10%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRIS---PKIWCA-GAGTAADTEAVT 85 T V + +G+V A+D+R+ G I KL ++ AG A +++V Sbjct: 1 TYCVAMHLADGLVFASDSRTNAG-IDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVI 59 Query: 86 QLIGSNIELHSLYTSREPRVVSALQML----KQHLFKYQGHIG------AYLIVAGVDPT 135 L+ I P V A ++ ++ + + G++ +V G Sbjct: 60 NLLQQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGGQIAG 119 Query: 136 GS-HLFSIHAHGSTDVG----YYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQA 190 G L+SI+ G+ +L LG S +L+ + D E+A++ A + + Sbjct: 120 GPPALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCALVSFDS 178 Query: 191 GIWNDLGSGSNVDVCVM 207 I ++L G +D+ V Sbjct: 179 TIRSNLSVGMPLDLLVY 195 >4HO7-A nrPDB Length = 179 Score = 66.6 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 14/183 (7%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGP-IVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 88 TTI+ V+ + VV+ D + T G IVA + KL RI+ + AG+ AD ++ + + Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGST 148 + I +R V A + + + A LIV + T I G+ Sbjct: 61 ENKIGEFPNQLTRA-AVELAKEWRTDRALR---RLEASLIVCSAEET----LEIDGQGNV 112 Query: 149 DVGYY---LSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVC 205 +++GSG A A + D+ +A K+A A++ D+ S + DV Sbjct: 113 ITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDIDVFSNEHWDVE 170 Query: 206 VME 208 V+E Sbjct: 171 VLE 173 >5L5W-G nrPDB Length = 252 Score = 63.9 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 33/208 (15%), Positives = 61/208 (29%), Gaps = 13/208 (6%) Query: 32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 91 + V+ + V+ + + ++ + + IS I G D + Sbjct: 42 SLAVRGKDCTVVISQKKVPDK-LLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAE 100 Query: 92 IELHSLYTSREPR---VVSALQMLKQHLFK--YQGHIGAYLIVAGVDPT-GSHLFSIHAH 145 + + + L Q + Y +G L VD G ++ Sbjct: 101 AAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPA 160 Query: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQD----LTKEEAIKLASDAIQAGIWNDLGSGSN 201 G + G LE+H+K+ + +E K+ AI I S Sbjct: 161 GYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSK 220 Query: 202 VDVCVMEIGKDAEYLRNYLTPNVREEKQ 229 D+ V KD + N+ E Sbjct: 221 NDLEVGVATKDKFF--TLSAENIEERLV 246 >1OFH-G nrPDB Length = 174 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 22/145 (15%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQLI 88 TTIV V+ N VV+ D + + G V N K+ R+ + K+ AG AD + +L Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 89 GSNIELHS-------LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGV-DPTGSHLF 140 +E+H + +++ R AL+ L+ L LI+ G+ D Sbjct: 61 ERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEK--ESLIITGIGDVVQPE-- 116 Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMA 165 L++GSG A++ Sbjct: 117 ---------EDQILAIGSGGNYALS 132 >1Q5Q-A nrPDB Length = 259 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 78/206 (37%), Gaps = 19/206 (9%) Query: 14 FLAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCA 73 + + S K + G ++V + F +GV+ A+ ST K+ + ++ A Sbjct: 12 IMRDRSELARKGIARGRSVVVLTFRDGVLFVAENPSTA--------LHKVSELYDRLGFA 63 Query: 74 GAGTAADTEAVTQLIGSNIELHSLYTSRE-----PRVVSALQMLKQHLFKYQGHIGAYLI 128 G + E + + + ++ R + Q L + + Sbjct: 64 AVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEIC 123 Query: 129 VAGV----DPTGSHLFSIHAHGST-DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKL 183 VA V P L+ I GS D +++ +G + + ++ DL E A+ + Sbjct: 124 VAEVGRVGSPKAPQLYRITYDGSIVDEQHFVVMGGTTEPIATAMRESYRADLDLEAAVGI 183 Query: 184 ASDAIQAGIWNDLGSGSNVDVCVMEI 209 A +A++ G + NVDV +E+ Sbjct: 184 AVNALRQGGAGEGEK-RNVDVASLEV 208 >1M4Y-A nrPDB Length = 171 Score = 52.3 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 17/180 (9%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISP-KIWCAGAGTAADTEAVTQLI 88 TTI+ V+ N V+ D + T G V N K+ ++ K+ AG+ AD + Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 89 GSNIELHSLYTSREPRVVSALQMLKQ-HLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGS 147 + L +A+++ K + + A L+VA D +F I +G Sbjct: 61 EAK-----LREWGGNLTKAAVELAKDWRTDRVLRRLEALLLVA--DKEN--IFIISGNGE 111 Query: 148 TDV--GYYLSLGSGSLAAMAVLESHWKQ-DLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 204 ++GSG A+A ++ + DL+ A ++ A+ + + N+ + Sbjct: 112 VIQPDDDAAAIGSGGPYALAAAKALLRNTDLS---AREIVEKAMTIAGEICIYTNQNIVI 168 >2Z3B-A nrPDB Length = 180 Score = 51.1 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 66/165 (40%), Gaps = 15/165 (9%) Query: 30 TTIVGVKFNNGVVIAADTRSTQG-PIVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQL 87 TTI V+ ++ D + T G +V K+ ++ + K+ AG+ AD + + Sbjct: 6 TTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTLFEK 65 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGS 147 + +E ++ + V A + + + + A LIV D L + G Sbjct: 66 FEAKLEEYN-GNLKRAAVELAKEWRSDKVLR---KLEAMLIVMNQDT----LLLVSGTGE 117 Query: 148 TDVGY--YLSLGSGSLAAMA---VLESHWKQDLTKEEAIKLASDA 187 L++GSG A+A L+ H + ++ E + A + Sbjct: 118 VIEPDDGILAIGSGGNYALAAGRALKKHAGESMSASEIARAALET 162 >5OVU-A nrPDB Length = 197 Score = 49.2 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 67/200 (33%), Gaps = 21/200 (10%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCA---KLHRISPKIWCAGAGTAADTEAVTQ 86 TT V V+ + V I AD T G + K+ + + AGT A + Sbjct: 1 TTCVVVRKGDEVAIGADALVTFGDTRLSRAYERNQKVIPVGDS-FVGLAGTTAHFPVMRS 59 Query: 87 LI---GSNIELHSLYTSREPRVVSALQMLKQHLFKY-----QGHIGAYLIVAGVDPTGSH 138 L+ G LH+ + + LK F + IV + +G Sbjct: 60 LLTGMGEECRLHT-RDDVFRTFLKVHEKLKNEYFINTKEDEDDPYESSQIVCLIANSGGI 118 Query: 139 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHW-KQDLTKEEAIKLASDAIQAGIWNDLG 197 + +GSG A+ + + + + DL ++ +A GI D Sbjct: 119 FGVYSYREVFSFDRFWGIGSGRNYALGAMHAVYDRTDLDAGAIARIGVEA---GIEFDKS 175 Query: 198 SGSNVDVCVME----IGKDA 213 S + +DV + KD Sbjct: 176 SAAPIDVHTVRLQVATNKDG 195 >3TY6-A nrPDB Length = 183 Score = 47.3 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 15/165 (9%) Query: 30 TTIVGVKFNNGVVIAADTRSTQGP-IVADKNCAKLHRI-SPKIWCAGAGTAADTEAVTQL 87 TTI V N +A D + T G +V K+ ++ K+ AG+ AD + ++ Sbjct: 10 TTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEM 69 Query: 88 IGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGS 147 +E ++ + V A Q + + + A LIV +D T + + G Sbjct: 70 FEGKLEEYN-GNLQRAAVEMAKQWRGDKMLR---QLEAMLIV--MDKT--TMLLVSGTGE 121 Query: 148 TDVGY--YLSLGSGSLAAMA---VLESHWKQDLTKEEAIKLASDA 187 L++GSG A++ L+ + + LT ++ K + + Sbjct: 122 VIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEI 166 >1HH2-P nrPDB Length = 344 Score = 33.0 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 30/81 (37%), Gaps = 6/81 (7%) Query: 172 KQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKS 231 ++ ++KEE I + A+ + + G+ NV+V + + + + E+ Sbjct: 15 EKGISKEEVIPILEKALVSAYRKNFGNSKNVEVVIDRNTGNIKVYQLLEVVEEVEDPATQ 74 Query: 232 YKFPRGTTAVLKESIVNICDI 252 + I + ++ Sbjct: 75 ISLEEA------KKIDPLAEV 89 >3ISH-A nrPDB Length = 311 Score = 31.5 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 174 DLTKEEAIKLASDA--IQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQK 230 D EEAI LA+ + D + + + + E+L Y+ ++ + Sbjct: 153 DTAVEEAIYLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASG 211 >5UQG-A nrPDB Length = 406 Score = 31.1 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 14/135 (10%) Query: 123 IGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAM--AVLESHWKQDLTKEEA 180 + ++AG D + LF+ Y G GSL AM + +++Q ++ Sbjct: 275 VMIGSLLAGTDESPGELFTYQG-----RQYKSYRGMGSLGAMQKGSSDRYFQQGTAQD-- 327 Query: 181 IKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTA 240 + GI + ++ V ++ Y+ E+ QK +F TTA Sbjct: 328 -----KLVPEGIEGRVPYVGSIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVEITTA 382 Query: 241 VLKESIVNICDIQEE 255 LKES V+ I E Sbjct: 383 GLKESHVHDVTITHE 397 >1RFZ-A nrPDB Length = 168 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 11/85 (12%) Query: 166 VLESHWKQDLTKEEAIKLASDAIQA-GIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNV 224 L+S + DLT EE I+ + I + N + +G +D ++ +D + Sbjct: 36 YLQSKYHPDLTMEECIENVNRVISKREVQNAILTGIQLD----KLAEDGRLDEPLQSIIR 91 Query: 225 REEKQKSYKFPRGTTAVLKESIVNI 249 R+E Y G +L SIVN+ Sbjct: 92 RDE--GLY----GVDEILALSIVNV 110 >5WKP-D nrPDB Length = 150 Score = 29.6 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQA 190 + G + + G GS A + L + W + T EEA+ + + I Sbjct: 53 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK 102 >5KZ5-a nrPDB Length = 118 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQA 190 + G + + G GS A + L + W + T EEA+ + + I Sbjct: 29 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK 78 >1WFZ-A nrPDB Length = 130 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 141 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQA 190 + G + + G GS A + L + W + T EEA+ + + I Sbjct: 42 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK 91 >4QUR-A nrPDB Length = 435 Score = 28.8 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 20/49 (40%) Query: 63 LHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQM 111 L + I+ + T D + QL +E+H L ++ + ++ Sbjct: 164 LRNLDGLIYICLSDTPPDFQTFAQLARPYLEVHDLKDAKVAFTSTIIEK 212 >1OGQ-A nrPDB Length = 313 Score = 28.8 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 19 SHTQPKATSTGTTIVGVKFNNGVVIAA--DTRSTQGPIVADKNCAKLHRISPKIWCAGAG 76 S T P + S+ +VG+ F+ + A D+ + + ++ +R++ KI A Sbjct: 138 SGTLPPSISSLPNLVGITFDGNRISGAIPDSYGSFSKLFTSMTISR-NRLTGKIPPTFAN 196 Query: 77 TAADTEAVTQLIGSNIE--LHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDP 134 A L + +E L+ S + + + K L G +G + G+D Sbjct: 197 LN---LAFVDLSRNMLEGDASVLFGSDKNTQK--IHLAKNSLAFDLGKVGLSKNLNGLDL 251 Query: 135 TGSHLFSIHAHGST 148 + ++ G T Sbjct: 252 RNNRIYGTLPQGLT 265 >2EEP-A nrPDB Length = 706 Score = 28.8 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 43/127 (33%), Gaps = 15/127 (11%) Query: 129 VAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAI 188 AG DP G+ L+ S ++ + ++ +DLT E + + Sbjct: 360 FAGFDPKGTRLYFESTEASPLERHFYCI---------DIKGGKTKDLTPESGMHRTQLSP 410 Query: 189 QAGIWNDLGSGSNV--DVCVMEIGKDAEYLRNYLTPN----VREEKQKSYKFPRGTTAVL 242 D+ V V V IGK + L P+ + E + + G T + Sbjct: 411 DGSAIIDIFQSPTVPRKVTVTNIGKGSHTLLEAKNPDTGYAMPEIRTGTIMAADGQTPLY 470 Query: 243 KESIVNI 249 + + + Sbjct: 471 YKLTMPL 477 >4ZFL-A nrPDB Length = 234 Score = 27.6 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 6 FDNYQRNNFLAENSHTQPKATSTGTTIVGVKFNNGVVIAAD 46 D R N LA N AT+ G T+ ++ +GVV+A++ Sbjct: 158 LDPNARLNILAANGSRLL-ATTWGDTLSVLRRPDGVVLASE 197 >4V8R-AG nrPDB Length = 590 Score = 27.3 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 7/52 (13%) Query: 15 LAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI 66 + E S TQ + GTT V +++A + + P + +KN + I Sbjct: 78 MLELSRTQDEEVGDGTTTV-------IILAGEILAQCAPYLIEKNIHPVIII 122 >5GW5-g nrPDB Length = 534 Score = 26.9 bits (58), Expect = 8.4, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 7/52 (13%) Query: 15 LAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRI 66 + E S TQ + GTT V +++A + + P + +KN + I Sbjct: 78 MLELSRTQDEEVGDGTTTV-------IILAGEILAQCAPYLIEKNIHPVIII 122 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.141 0.346 Lambda K H 0.267 0.0432 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,430,438 Number of Sequences: 36641 Number of extensions: 367341 Number of successful extensions: 1458 Number of sequences better than 10.0: 101 Number of HSP's better than 10.0 without gapping: 146 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1125 Number of HSP's gapped (non-prelim): 183 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.9 bits)