BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24752 (427 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IBU-A nrPDB 803 0.0 6BN2-A nrPDB 454 e-128 6BJB-A nrPDB 416 e-117 6BJA-A nrPDB 389 e-108 6ARG-A nrPDB 357 6e-99 5XYJ-B nrPDB 355 2e-98 4N44-A nrPDB 338 4e-93 4E1L-A nrPDB 313 1e-85 4O9A-A nrPDB 311 5e-85 5LP7-H nrPDB 310 6e-85 1NL7-A nrPDB 303 8e-83 1WL4-A nrPDB 302 2e-82 4DD5-A nrPDB 301 3e-82 4WYS-A nrPDB 289 1e-78 4NZS-A nrPDB 276 1e-74 3SS6-A nrPDB 262 2e-70 4C2K-A nrPDB 261 5e-70 1ULQ-A nrPDB 258 3e-69 5CBQ-A nrPDB 229 1e-60 1PXT-A nrPDB 200 8e-52 2WUA-A nrPDB 198 4e-51 2C7Y-A nrPDB 191 6e-49 4UBW-A nrPDB 190 8e-49 3GOA-A nrPDB 189 3e-48 1WDK-C nrPDB 188 4e-48 5ZQZ-B nrPDB 186 1e-47 2IIK-A nrPDB 181 4e-46 3SVK-A nrPDB 181 6e-46 4B3J-C nrPDB 177 6e-45 6ESQ-A nrPDB 49 4e-06 6HRV-A nrPDB 48 8e-06 4BI9-A nrPDB 46 4e-05 1OXH-A nrPDB 38 0.007 5LNQ-A nrPDB 37 0.024 4YZO-A nrPDB 36 0.034 4JPF-A nrPDB 35 0.075 3KZU-A nrPDB 34 0.12 2IWZ-A nrPDB 32 0.48 5XTD-T nrPDB 32 0.56 3E60-A nrPDB 32 0.66 4JGA-A nrPDB 32 0.68 2IX4-A nrPDB 32 0.69 5GUP-F nrPDB 31 0.79 1J3N-A nrPDB 31 0.86 2GP6-A nrPDB 31 0.99 3U0E-A nrPDB 31 0.99 6G2J-R nrPDB 31 1.0 5JP1-A nrPDB 31 1.1 5M3K-C nrPDB 30 1.4 4JRH-A nrPDB 30 1.4 4R8E-A nrPDB 30 1.5 6QSP-A nrPDB 30 1.5 2WV9-A nrPDB 30 1.6 5W2O-A nrPDB 30 1.6 5O31-R nrPDB 30 1.7 3HO9-A nrPDB 29 4.5 4QAV-A nrPDB 28 6.2 4LS7-A nrPDB 28 7.4 4DDO-A nrPDB 28 8.6 >2IBU-A nrPDB Length = 395 Score = 803 bits (2073), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 35 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 94 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV Sbjct: 3 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 62 Query: 95 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME Sbjct: 63 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 122 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY Sbjct: 123 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 182 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE Sbjct: 183 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 242 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS Sbjct: 243 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 302 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI Sbjct: 303 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 362 Query: 395 VGHLTHALKQGEYGLASICNGGGGASAMLIQKL 427 VGHLTHALKQGEYGLASICNGGGGASAMLIQKL Sbjct: 363 VGHLTHALKQGEYGLASICNGGGGASAMLIQKL 395 >6BN2-A nrPDB Length = 401 Score = 454 bits (1169), Expect = e-128, Method: Compositional matrix adjust. Identities = 229/393 (58%), Positives = 295/393 (75%), Gaps = 5/393 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +KEV IVSA RTP+GSF+GSLS +PAT+LG++AI+GA++K + E+++ YMGNVLQ G Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAG 68 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 EGQAP +QA LGAGLP +TP T +NKVCASGMKA+MMA+Q++ G + +VAGGME+MS Sbjct: 69 EGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMSQ 128 Query: 159 VP-YVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 217 VP Y+ R G +KL+D ++KDGLTDVY+K HMG+CAE AK+ NI R EQDA+AI Sbjct: 129 VPHYIDGRNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDAFAIQ 188 Query: 218 SYTRSKAAWEAGKFGNEVIPVTV-TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENG 276 SY RS AW GKF EV+PV++ KG+P ++ EDEEYK V F ++P L TVFQKENG Sbjct: 189 SYERSAKAWSEGKFKEEVVPVSIPQRKGEP-IIFAEDEEYKNVKFDRIPTLPTVFQKENG 247 Query: 277 TVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV 336 TVTAANASTLNDGA+ALVLM+ + + L + PLA+IV++ADAA P F AP A + Sbjct: 248 TVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKALPIA 307 Query: 337 LKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVG 396 L L DI +E NEAFS+V LAN K+L +D KVN+NGGAV+LGHP+G SG+RI+ Sbjct: 308 LAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGSRIIV 367 Query: 397 HLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 L + LKQ +YG A+ICNGGGGASA++I+ + Sbjct: 368 TLINVLKQNNAKYGAAAICNGGGGASAIVIENI 400 >6BJB-A nrPDB Length = 393 Score = 416 bits (1069), Expect = e-117, Method: Compositional matrix adjust. Identities = 220/393 (55%), Positives = 280/393 (71%), Gaps = 3/393 (0%) Query: 35 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 94 S+P + +VV V A RTPIGSF + + +P T LG A++GA++ A + V+EA++G V Sbjct: 4 SRP-ITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVV 62 Query: 95 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 + GQ P RQ VLGAG +ST T +NK+ ASGMKAI A+ L Q+++VAGGME Sbjct: 63 VPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGME 122 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SMS VP+ + RG P+GG KL D I +DGL DVYN I MG+CA+ AK+ I R EQD Y Sbjct: 123 SMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKY 182 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 AI SY RS AAW+ G F E+IP+ VT +G+ + V+EDEEYK+V+F K+PKLK F E Sbjct: 183 AILSYKRSAAAWKEGIFAKEIIPLEVT-QGKKTITVEEDEEYKKVNFEKIPKLKPAFTSE 241 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 G+VTAANASTLNDGAA +V+ T D AK+ + PLAR++A+ DAA PIDF IAP Sbjct: 242 -GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIP 300 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 VLK GL+ +DI +WE+NEAF++V L +K L +D KVNI+GGAVSLGHPIGMSGARI Sbjct: 301 KVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARI 360 Query: 395 VGHLTHALKQGEYGLASICNGGGGASAMLIQKL 427 VGHL H LK G+ G A+ICNGGGGA M+I+KL Sbjct: 361 VGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 393 >6BJA-A nrPDB Length = 397 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 195/389 (50%), Positives = 267/389 (68%), Gaps = 1/389 (0%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 K+V I+SA RTPI SF +L+ L A LG + + AI+++ +P ++E +GNVL G Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGL 68 Query: 100 GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNV 159 GQ RQ + + +P S+ C TINKVC+S MKAI+M +Q++ G++ ++VA G ESMSN Sbjct: 69 GQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNA 128 Query: 160 PYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSY 219 P+ + RG P+GGV+L D + +DGL D MG CAE T K R + DAYAI SY Sbjct: 129 PFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAIESY 188 Query: 220 TRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE-NGTV 278 +++ AW+ G F EV+PV+V K VV+ EDEEYKR+ KVP L F K+ +GT+ Sbjct: 189 RKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPAFLKDGSGTI 248 Query: 279 TAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLK 338 TAANAST+NDGAAA VL + + + + P+A+++++A+A VEPIDF +AP A +L Sbjct: 249 TAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAVKQLLS 308 Query: 339 DVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHL 398 GL +E IA+WE+NEAFS+ LA IK L +DP++VN+ GGAV+LGHP+G SGARIV L Sbjct: 309 QSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGARIVVTL 368 Query: 399 THALKQGEYGLASICNGGGGASAMLIQKL 427 HALK E G+A+ICNGGG ASA+LI+KL Sbjct: 369 VHALKSDELGVAAICNGGGEASAILIKKL 397 >6ARG-A nrPDB Length = 399 Score = 357 bits (916), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 194/396 (48%), Positives = 268/396 (67%), Gaps = 6/396 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKA-GIPKEEVKEAYMGNVLQ 96 +L V IVS+ RTP+GSFLGSLS L A +LG+ AI+ A+ K G+ +V+E + GNV+ Sbjct: 4 SLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVIS 63 Query: 97 GGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM 156 GQ P RQ LGAGL ST CTT+NKVCASG+KAI++ +Q++M G+ DV+VAGG ESM Sbjct: 64 ANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESM 123 Query: 157 SNVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SN P+ + R YG L D I+KDGLTD + MG AE A+ +R +QD Y Sbjct: 124 SNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEY 183 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVT-VKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQK 273 AI +Y +++AA +AG F E+ P+ + +G+PDV V +DEE K ++ K+ +K F Sbjct: 184 AIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIP 243 Query: 274 ENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAA 333 +GTVTA N+S LNDGAAA+VL++ K LN+ P+A+I+ + DAA +P F AP A Sbjct: 244 GSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAI 303 Query: 334 SMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGAR 393 LK G+ ++ I +E+NEAFS+V LAN+K+L I +KVN++GGAV++GHPIG SGAR Sbjct: 304 PKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGAR 363 Query: 394 IVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 I+ L L K+G+ G A ICNGGGGASA++++ L Sbjct: 364 ILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 399 >5XYJ-B nrPDB Length = 408 Score = 355 bits (912), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 192/398 (48%), Positives = 264/398 (66%), Gaps = 12/398 (3%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPK----EEVKEAYMGNVL 95 + V IVS RTPIGSF GSLS A +LG++A++GA+ K +P+ ++ E GNVL Sbjct: 13 QNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAK--VPELDASKDFDEIIFGNVL 70 Query: 96 QGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 GQAP RQ L AGL +T+NKV AS MKAI++ +QS+ CG+ DV+VAGG ES Sbjct: 71 SANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCES 130 Query: 156 MSNVPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDA 213 M+N PY M R +G L D + +DGL D Y+ + MG AE A+ +I R +QD Sbjct: 131 MTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDN 190 Query: 214 YAINSYTRSKAAWEAGKFGNEVIPVTVT-VKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 272 +AI SY +S+ + + GKF NE++PVT+ +G+PD V +DEE R+ K+ +TVFQ Sbjct: 191 FAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQ 250 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 KENGTVTAANAS +NDGAAA++L++ K N+ PLA I + +AA +P DF AP A Sbjct: 251 KENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPSLA 310 Query: 333 ASMVLKDVGLKK-EDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 LK G++ + +E NEAFS+V L N K+L++DP KVN+ GGAV+LGHP+G SG Sbjct: 311 VPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSG 370 Query: 392 ARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 AR+V L L+Q G+ G+A+ICNGGGGAS+++I+K+ Sbjct: 371 ARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIEKI 408 >4N44-A nrPDB Length = 400 Score = 338 bits (866), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 182/394 (46%), Positives = 256/394 (64%), Gaps = 9/394 (2%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +KEVVI SA RT IGS+ SL +PA LG+ AI+ A++KAGI E+V E +GNVLQ G Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ P RQA AGLP+ P TINKVC SG++ + +A+Q + G DV++AGGME+MS Sbjct: 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120 Query: 159 VPYVMNRGSTPY--GGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 PY+ N Y G K D ++ DGL D +N HMG AEN A++ NI+R EQD +A+ Sbjct: 121 APYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFAL 180 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRV--DFSKVPKLKTVFQKE 274 S +++ A ++G+F +E++P V +KG+ V + +E+ R + KLK F+K+ Sbjct: 181 ASQKKAEEAIKSGQFKDEIVP--VVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKD 238 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS LND AA LV+M+A+ AK L V PLA+IV++ A V+P P YA Sbjct: 239 -GTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATK 297 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 ++ G +++ + E NEAF+ LA K L+ D KVN+NGGA++LGHPIG SGARI Sbjct: 298 AAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARI 357 Query: 395 VGHLTHALKQ--GEYGLASICNGGGGASAMLIQK 426 + L HA+++ + GLA++C GGG +A+L++K Sbjct: 358 LVTLVHAMQKRDAKKGLATLCIGGGQGTAILLEK 391 >4E1L-A nrPDB Length = 395 Score = 313 bits (801), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 168/393 (42%), Positives = 245/393 (62%), Gaps = 6/393 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +K+VVIVSA RTPIGSF G A +LG+IA++ AI + G+ E+ E +GNVLQ G Sbjct: 4 MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTG 63 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ RQ + AG+P S P T+NK+C SG+K++ +A+QS+ G DV++AGG E+MS Sbjct: 64 LGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMSQ 123 Query: 159 VPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 PY++ R + G + + D ++ DGL D +N+ HMG AEN A K R QD A+ Sbjct: 124 APYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKLAL 183 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTV-KGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 S +++ A + +F E++PV V + +G+ + + K++ + F + KLK F+K+ Sbjct: 184 ESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAFKKD- 242 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 GTVTA NAS +NDGAA L+LM+ A L + PLA+I ++A A VEP P+ A Sbjct: 243 GTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIPATRK 302 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 LK GL DI + E NEAF+ LA L+ID K+N+NGGA++LGHPIG SGARI+ Sbjct: 303 ALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASGARIL 362 Query: 396 GHLTHALKQG--EYGLASICNGGGGASAMLIQK 426 L + +++ E GLA++C GGG +M++ + Sbjct: 363 VTLIYEMQKRKVETGLATLCIGGGQGISMVVSR 395 >4O9A-A nrPDB Length = 398 Score = 311 bits (796), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 178/391 (45%), Positives = 251/391 (64%), Gaps = 6/391 (1%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 +VVIVSA RT +G F GSL+ +PA +LG++ I+ A+E+AG+ E+V E MG VL G G Sbjct: 8 DVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSG 67 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 Q P RQA + AGLP P TINKV SG+KA+M+A+ ++M G +++VAGG E+MS P Sbjct: 68 QNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAP 127 Query: 161 YVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINS 218 +V+ +R G KL D ++ DGL DVYN+ HMG AEN AK+ I R QD +A+ S Sbjct: 128 HVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVGS 187 Query: 219 YTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKENGT 277 +++AA +AGKF E++PV + + V K DE ++ + LK F K GT Sbjct: 188 QNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKA-GT 246 Query: 278 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVL 337 VTAANAS LNDGAAA+V+M+A AK L +TPLA I ++A+A V+P + PV A+ L Sbjct: 247 VTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRAL 306 Query: 338 KDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGH 397 +D+ + E+NEAF+ LA + + D KVN+NGGA+++GHPIG SG RI+ Sbjct: 307 SRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVT 366 Query: 398 LTHALKQ--GEYGLASICNGGGGASAMLIQK 426 L H +K+ + GLAS+C GGG A+ +++ Sbjct: 367 LLHEMKRRDAKKGLASLCIGGGMGVALAVER 397 >5LP7-H nrPDB Length = 393 Score = 310 bits (795), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 166/392 (42%), Positives = 250/392 (63%), Gaps = 6/392 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +++ VIVSA RTP G F G L + A +LG I ++ A+++AG+ ++V+ MG V+Q G Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ P+RQA AG+P S P T+NKVCASG++A+ + Q + D++VAGGMESMSN Sbjct: 61 SGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSN 120 Query: 159 VPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 +PY + R G +L DL+V DGLT ++++HM AK+ I+R EQD +A+ Sbjct: 121 IPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWAL 180 Query: 217 NSYTRSKAAWEAGKFGNEVIPVT-VTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 S+ R+ A + GKF +E++PV + KG+P+VV K++ + ++ KL ++ + Sbjct: 181 RSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPIY-ASD 239 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 G++TA NA +NDGA A VLM+ + A L PLA I+ F+ + + AP +A + Sbjct: 240 GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGFAINK 299 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 +LK GL +DI ++EVNEAF+ VVL K++ D +KVN+NGGA++LGHPIG SGARI+ Sbjct: 300 LLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASGARIL 359 Query: 396 GHLTHALKQ--GEYGLASICNGGGGASAMLIQ 425 L + LK+ G G+A+IC+G A+L+Q Sbjct: 360 MTLVYELKRRGGGLGVAAICSGAAQGDAVLVQ 391 >1NL7-A nrPDB Length = 392 Score = 303 bits (777), Expect = 8e-83, Method: Compositional matrix adjust. Identities = 167/391 (42%), Positives = 238/391 (60%), Gaps = 8/391 (2%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101 +VI SA RT +GSF G+ + PA +LG+ I +E+AG+ EV E +G VL GEGQ Sbjct: 5 IVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAGEGQ 64 Query: 102 APTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY 161 P RQA + AG+P +N++C SG++A+ + Q + G ++VAGGMESMS P+ Sbjct: 65 NPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAPH 124 Query: 162 VMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYT 220 + RG G K+ D ++KDGLTD + HMG+ AEN AK+ ++R+EQDA+A+ S Sbjct: 125 CAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVASQN 184 Query: 221 RSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR--VDFSKVPKLKTVFQKENGTV 278 +++AA + G+F +E++P V KG+ + + +EY R + KL+ F KE GTV Sbjct: 185 KAEAAQKDGRFKDEIVPFIV--KGRKGDITVDADEYIRHGATLDSMAKLRPAFDKE-GTV 241 Query: 279 TAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLK 338 TA NAS LNDGAAA +LM+ A R + PL RIV++A V+P P+ A+ L+ Sbjct: 242 TAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKALE 301 Query: 339 DVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHL 398 G K D+ + E NEAF+ A K L DP VN+NGGA+++GHPIG SGARI+ L Sbjct: 302 RAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILNTL 361 Query: 399 THALKQ--GEYGLASICNGGGGASAMLIQKL 427 +K+ GLA++C GGG AM I+ L Sbjct: 362 LFEMKRRGARKGLATLCIGGGMGVAMCIESL 392 >1WL4-A nrPDB Length = 397 Score = 302 bits (773), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 170/390 (43%), Positives = 243/390 (62%), Gaps = 6/390 (1%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101 VVIVSA RT IGSF G+L+ +P LGS I+ +++A + E+V E G+VL G GQ Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67 Query: 102 APTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY 161 P RQA +GAG+P S P + +C SG+KA+ +A QS+ G ++VAGGME+MS P+ Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127 Query: 162 VMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYT 220 + R G + L D I+ DGLTD ++ HMG AEN AKK ++R +QD A+ S Sbjct: 128 LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQN 187 Query: 221 RSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKE-NGTV 278 R++ A +AG F E++PV V+ + + + VK DE + + + KLK F + GTV Sbjct: 188 RTENAQKAGHFDKEIVPVLVSTR-KGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTV 246 Query: 279 TAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLK 338 T ANAS +NDGAAA+VLM A + +TPLARIV+++ VEP I P+ A + Sbjct: 247 TPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVT 306 Query: 339 DVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHL 398 G ED+ ++E+NEAF+ V A +K L ++P+KVNI GGA++LGHP+G SG RI+ L Sbjct: 307 KAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTL 366 Query: 399 THALKQ--GEYGLASICNGGGGASAMLIQK 426 H L++ G+A++C GGG AM +Q+ Sbjct: 367 LHTLERMGRSRGVAALCIGGGMGIAMCVQR 396 >4DD5-A nrPDB Length = 396 Score = 301 bits (772), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 169/394 (42%), Positives = 245/394 (62%), Gaps = 9/394 (2%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 ++EVVI SA RT +GSF G+ + A +LG A + AI++A I + + E+ +G VL G Sbjct: 6 MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTAG 65 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ RQ LGAG+P+ P TIN VC SG++++ MASQ + G D+M+ GG E+MS Sbjct: 66 LGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMSM 125 Query: 159 VPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 PY++ R G D ++KDGL+D++N HMG AEN A++ NI R EQD A+ Sbjct: 126 SPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELAL 185 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQP-DVVVKEDEEYK-RVDFSKVPKLKTVFQKE 274 S +++ A GKF E++PV + KG+ D VV +DE K K+ KL+ F+K+ Sbjct: 186 ASQNKAEKAQAEGKFDEEIVPVVI--KGRKGDTVVDKDEYIKPGTTMEKLAKLRPAFKKD 243 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS +NDGAA LV+M + A+ L + PLA IV++ A V+P PV A Sbjct: 244 -GTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVPATK 302 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 L+ + EDI + E NEAF+ +A I+ L ID KVN+NGGA+++GHPIG SGARI Sbjct: 303 KALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSGARI 362 Query: 395 VGHLTHALKQ--GEYGLASICNGGGGASAMLIQK 426 + L + +K+ + GLA++C GGG + +++++ Sbjct: 363 LTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR 396 >4WYS-A nrPDB Length = 405 Score = 289 bits (740), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 175/394 (44%), Positives = 241/394 (61%), Gaps = 6/394 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +K VIVSA RT IGSF GSL+ A LG+ I+ AIE+A I + V E MGNVLQ G Sbjct: 4 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 63 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ P RQA+L +GL + T+NKVC SG+K++ +A+Q++ G +VAGGME+MS Sbjct: 64 LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSL 123 Query: 159 VPYVMN---RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 PY+++ R G ++ D+I++DGL + HMG AEN AK+ I R QD A Sbjct: 124 APYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELA 183 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 ++S ++ AA E+G F E++PV V + + V +++ + L+ F K Sbjct: 184 LHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKA- 242 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 GTVTA NAS +NDGAAALV+M AA +TPLARI ++A V P + PV A Sbjct: 243 GTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQK 302 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 L+ GL+ DI + E NEAF+ LA K L D +KVN+NGGA++LGHPIG SGARI+ Sbjct: 303 ALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARIL 362 Query: 396 GHLTHALKQGE--YGLASICNGGGGASAMLIQKL 427 L HA++ + GLA++C GGG AM+I++L Sbjct: 363 VTLLHAMQARDKTLGLATLCIGGGQGIAMVIERL 396 >4NZS-A nrPDB Length = 399 Score = 276 bits (706), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 160/399 (40%), Positives = 237/399 (59%), Gaps = 18/399 (4%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 +EVV+VS RT IG+F GSL + +LG++ ++ A+ +A + ++V GNV+Q Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQ--- 64 Query: 100 GQAPT-----RQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 P R A + G+ I+ P T+N++C SG++AI+ A+Q+++ G DV + GG E Sbjct: 65 -TEPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAE 123 Query: 155 SMSNVPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 212 SMS PY+ R G L D+++ L D +++IHMG AEN AK+ +I+R +QD Sbjct: 124 SMSRAPYLAPAARWGARMGDAGLVDMMLG-ALHDPFHRIHMGVTAENVAKEYDISRAQQD 182 Query: 213 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVD--FSKVPKLKTV 270 A+ S+ R+ AA +AG F ++++PV KG+ V + +E+ R D + KL+ V Sbjct: 183 EAALESHRRASAAIKAGYFKDQIVPVVS--KGRKGDVTFDTDEHVRHDATIDDMTKLRPV 240 Query: 271 FQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPV 330 F KENGTVTA NAS LND AAA+V+M A+R + PLAR+V++ A V+P I PV Sbjct: 241 FVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPV 300 Query: 331 YAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMS 390 A + L+ GL+ D+ + E NEAF+ A K L +DP KVN NG +SLGHPIG + Sbjct: 301 PATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGAT 360 Query: 391 GARIVGHLTHALK--QGEYGLASICNGGGGASAMLIQKL 427 GA I H L QG Y L ++C GGG A + +++ Sbjct: 361 GALITVKALHELNRVQGRYALVTMCIGGGQGIAAIFERI 399 >3SS6-A nrPDB Length = 394 Score = 262 bits (669), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 158/397 (39%), Positives = 235/397 (59%), Gaps = 14/397 (3%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 + VVI +A R+PIG+F G+L + +L +Q A+++ G+ EV E +G+ +Q Sbjct: 4 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRT 63 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 + R A L AG P + TI + C+SGM+AIM A+ + G +V+VAGG+E+MS+ Sbjct: 64 DEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMSS 123 Query: 159 VPYVMNRGSTPYGGVKLEDLIVKDG----LTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 PY + + G +L+ ++D L D + I MG AEN ++ I R EQD Sbjct: 124 SPYALKQHRW---GQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEV 180 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFS--KVPKLKTVFQ 272 A+ S+T + A E+G F ++++P+T+ + + +VV +DE + R D + K+ LK F+ Sbjct: 181 ALRSHTLALKAIESGYFDDQIVPITIKER-RKEVVFSKDE-HPRADITAEKLAGLKPAFR 238 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 K +G+VTA NAS LNDG+A LVLM+ + AK + PLARIV ++ A V+P I P A Sbjct: 239 K-DGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPA 297 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 L+ V ED + E+NEAF+ LA K L++D +KVN+NG V LGHPIG +GA Sbjct: 298 IRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGA 357 Query: 393 RIVGHLTHALKQG--EYGLASICNGGGGASAMLIQKL 427 RI L H LK+ E G+AS+C GGG A+ I+ L Sbjct: 358 RITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 394 >4C2K-A nrPDB Length = 417 Score = 261 bits (667), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 158/393 (40%), Positives = 224/393 (56%), Gaps = 8/393 (2%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 L+ V +V+A RTP G++ G L AT L A + A+ + E V MGNVLQ Sbjct: 24 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 83 Query: 99 -EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 + R L G+P TP TIN++C SG ++I+ Q + +V++ GG ESMS Sbjct: 84 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 143 Query: 158 NVPYVMN--RGSTPYGG-VKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 PY + R T G +KLED + LTD + ++ M AEN A K I+R E D Y Sbjct: 144 QAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKY 202 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 A+ S R KAA +AG F +E+ P+ V K + ++ + ++ KL VF+K+ Sbjct: 203 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 262 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS + DGA A+++ + DA K+ N TPLARIV + + +P I PV A S Sbjct: 263 -GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAIS 321 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 LK GL +D+ + EVNEAF+ LA + L++D K N+NGGA++LGHP+G SG+RI Sbjct: 322 GALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 381 Query: 395 VGHLTHALKQ--GEYGLASICNGGGGASAMLIQ 425 HL H L++ G+Y + S C GGG A++IQ Sbjct: 382 TAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 414 >1ULQ-A nrPDB Length = 401 Score = 258 bits (660), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 154/403 (38%), Positives = 241/403 (59%), Gaps = 17/403 (4%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 + E IV A RTPIG G+L+ + L + A+ ++++G+PKEEV++ Y G Q G Sbjct: 1 MPEAWIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAG 60 Query: 99 E-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 E + R A+L AG P+ T+N++C SG++A+ A++++ G V + G+ESMS Sbjct: 61 EDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMS 120 Query: 158 NVPYVM---NRGSTPYGGVKLEDL-----IVKDGLTDVYNKIHMGSCAENTAKKLNIARN 209 PY + RG P G + + D V + +Y MG AEN A+ I R Sbjct: 121 RAPYAVPKPERG-FPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRRE 179 Query: 210 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLK 268 EQD +A+ S+ ++ AWE G+F +EV+PV V +G+ +++V++DE +R K+ L+ Sbjct: 180 EQDRFALLSHQKAVRAWEEGRFQDEVVPVPVK-RGKEEILVEQDEGPRRDTSLEKLAALR 238 Query: 269 TVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIA 328 VF +E GTVTA N+S LNDGAAA++L++ D AK + PLAR+ A A A V P I Sbjct: 239 PVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGIG 297 Query: 329 PVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIK--MLEIDPQKVNINGGAVSLGHP 386 PV A L+ GL D+ + E+NEAF+ LA ++ L ++ Q++N NGGA++LGHP Sbjct: 298 PVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGHP 357 Query: 387 IGMSGARIVGHLTHALKQG--EYGLASICNGGGGASAMLIQKL 427 +G SGARI+ L H +++ ++GLA++C G G A++++ + Sbjct: 358 LGASGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVVEGM 400 >5CBQ-A nrPDB Length = 413 Score = 229 bits (585), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 143/407 (35%), Positives = 220/407 (54%), Gaps = 21/407 (5%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 ++++ VI RTPIG + G L A LG A++G +E+ GI ++V++ +G+ Sbjct: 8 SMRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYPN 67 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 E A R L AGLPI+ P +++ C SG++A++ A + G D++VAGG ESMS Sbjct: 68 SEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESMS 127 Query: 158 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIH-----MGSCAENTAKKLNIARNE 210 NV + R GV++ D + + G T K H M AEN ++ +I+R E Sbjct: 128 NVAFYSTDMRWGGARTGVQIHDGLAR-GRTTAGGKFHPVPGGMLETAENLRREYHISRTE 186 Query: 211 QDAYAINSYTRSKAAWEAGKFGNEVIPVTV-TVKGQPDVVVKEDEEYKRVDFS--KVPKL 267 QD A+ S+ R+ AA G E+IPV V T G+ + V +E+ R D + + KL Sbjct: 187 QDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISV---DEHPRADTTVEALAKL 243 Query: 268 KTVFQKEN--GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDF 325 K V K++ TVTA N+S ND A+ ++ T + A L + PL R+V++ A V P Sbjct: 244 KPVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLM 303 Query: 326 PIAPVYAASMVLKDVGLKKEDIAMWEVNEAF---SLVVLANIKMLEIDPQKVNINGGAVS 382 I PV A + L GL DI + E+NEAF +L V+ K E D ++ N+ G +S Sbjct: 304 GIGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGIS 363 Query: 383 LGHPIGMSGARIVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 LGHP+G +G R++ L L ++ YGL ++C GGG A + +++ Sbjct: 364 LGHPVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVFERV 410 >1PXT-A nrPDB Length = 390 Score = 200 bits (509), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 136/395 (34%), Positives = 207/395 (52%), Gaps = 19/395 (4%) Query: 40 KEVVIVSATRTPIGS-FLGSLSLLPATKLGSIAIQGAIEKAGIPKEE----VKEAYMGNV 94 ++VVIV+A R+ IG F G+ + L + I + P ++E GNV Sbjct: 7 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 66 Query: 95 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 L G G R A L +G+P STP +N+ C+SG+ A+ + + G D+ +A G+E Sbjct: 67 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 126 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SM+N +N P G + E+L I MG EN A I+R +QD + Sbjct: 127 SMTNNYKNVN----PLGMISSEELQKNREAKKCL--IPMGITNENVAANFKISRKDQDEF 180 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR--VDFSKVPKLKTVFQ 272 A NSY ++ A G F +E++P+ + PD + + +E R V + ++ F Sbjct: 181 AANSYQKAYKAKNEGLFEDEILPIKL-----PDGSICQSDEGPRPNVTAESLSSIRPAFI 235 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 K+ GT TA NAS ++DG A ++L A +LN+ L R + F V P + P YA Sbjct: 236 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 295 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 VL+ GL+ +DI ++E+NEAF+ L I L ID KVN GGA++LGHP+G +GA Sbjct: 296 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 355 Query: 393 RIVGHLTHALKQGEYGLASICNGGG-GASAMLIQK 426 R V + LK+ + G+ S+C G G GA+A+ I++ Sbjct: 356 RQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE 390 >2WUA-A nrPDB Length = 440 Score = 198 bits (503), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 131/399 (32%), Positives = 214/399 (53%), Gaps = 24/399 (6%) Query: 41 EVVIVSATRTPI-GSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 +VVIV+A R+P+ + G L + + ++ IEK I EV + +G+VL G Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 100 GQAP-TRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 +A R A AG P + P T+N+ C+SG++A+ + ++ G D+ + G+ESM+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 159 VPYVMNRGSTPYGGVKLEDLI-VKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 217 P P K++ + +D L + MG +EN A+K +I R EQD A+ Sbjct: 154 NPMAWEGSVNP----KVKTMAQAQDCL------LPMGITSENVAQKFSITRQEQDQAAVG 203 Query: 218 SYTRSKAAWEAGKFGNEVIPVTVTV------KGQPDVVVKEDEEYKRVDFSKVPKLKTVF 271 S+ ++ AA AG+F +E+IP+ + +P + +D + + KLK VF Sbjct: 204 SHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPVF 263 Query: 272 QKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVY 331 +K+ G+ TA +S ++DGA A++LM A + + L FA V P I P Sbjct: 264 RKD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAV 322 Query: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 A +K GL+ +DI ++E+NEAF+ + K LEIDPQK+N+NGGA+++GHP+G +G Sbjct: 323 AIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATG 382 Query: 392 ARIVGHLTHALKQ----GEYGLASICNGGGGASAMLIQK 426 AR V L H +K+ +G+ S+C G G +A + ++ Sbjct: 383 ARCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVFER 421 >2C7Y-A nrPDB Length = 404 Score = 191 bits (484), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 130/398 (32%), Positives = 208/398 (52%), Gaps = 22/398 (5%) Query: 41 EVVIVSATRTPI-GSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 +VVIV+A RTP+ S G+ L + ++ IEK + EV + +G VL G Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 100 GQAP-TRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 +A R A AG P + T+N+ C+SG++A+ + ++ G D+ + G+ESM+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 159 VPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINS 218 P P VK + MG +EN A++ ++R EQD A++S Sbjct: 134 NPMAWEGSVNP---------AVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVDS 184 Query: 219 YTRSKAAWEAGKFGNEVIPVTV------TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 272 + ++ AA AGKF +E+IPV T +P V +D + + KLK VF+ Sbjct: 185 HRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVFK 244 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 K+ GT TA N+S ++DGA A++LM A + + L FA V+P I P A Sbjct: 245 KD-GTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVA 303 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 +K GL+ +DI ++E+NEAF+ + L +DP+K+N+NGGA+++GHP+G +GA Sbjct: 304 IPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 363 Query: 393 RIVGHLTHALKQ----GEYGLASICNGGGGASAMLIQK 426 R V L H +K+ +G+ S+C G G +A + ++ Sbjct: 364 RCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFER 401 >4UBW-A nrPDB Length = 399 Score = 190 bits (483), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 138/399 (34%), Positives = 212/399 (53%), Gaps = 26/399 (6%) Query: 43 VIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKE----EVKEAYMGNVLQGG 98 VIV ATR+PIG G LS L AT+L + ++KAGI +V++ G V Q G Sbjct: 13 VIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFG 72 Query: 99 E-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 E +R A L AGLP TT++ C SG +A + + + G DV +A G+E+MS Sbjct: 73 EQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAMS 132 Query: 158 NVPYVMNRGSTPYGGVKLEDLI-VKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 V N G LI + D+ N+ AE AK+ I R + D + + Sbjct: 133 RVGLGANAGPD-------RSLIRAQSWDIDLPNQF---EAAERIAKRRGITREDVDVFGL 182 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTV---KGQPD---VVVKEDEEYKRVDFSKVPKLKTV 270 S R++ AW G+F E+ P+ V + QP +V D+ + + + +LK V Sbjct: 183 ESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMAGLGELKPV 242 Query: 271 FQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPV 330 E G TA +S ++DGAAA++ M A+ +TP ARIVA A EP PV Sbjct: 243 L--EGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPV 300 Query: 331 YAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMS 390 + + VL+ G+K DI + E+NEAF+ VVL+ ++ E D +VN+NGGA++LGHP+G + Sbjct: 301 QSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCT 360 Query: 391 GARIVGHLTHALKQGEYGLA--SICNGGGGASAMLIQKL 427 G+R++ H L++ + LA ++C GG ++ +I+++ Sbjct: 361 GSRLITTALHELERTDQSLALITMCAGGALSTGTIIERI 399 >3GOA-A nrPDB Length = 387 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 138/402 (34%), Positives = 219/402 (54%), Gaps = 28/402 (6%) Query: 39 LKEVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEK-AGIPKEEVKEAYMGNVLQ 96 +++VVIV A RTP+G S G+ + A L + ++ + + + + + Y G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 97 GGE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 E G R A L A +P S P T+N++C S M+A+ A++ +M G V + GG+E Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 156 MSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 M +VP M+ G + G+ ++ G+ MG AE ++ I+R QD +A Sbjct: 121 MGHVP--MSHGVDFHPGLS-RNVAKAAGM--------MGLTAEMLSRLHGISREMQDQFA 169 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKE---DEEYK-RVDFSKVPKLKTVF 271 S+ R+ AA ++G F E+IP T D V+K+ DE + + L+ F Sbjct: 170 ARSHARAWAATQSGAFKTEIIP---TGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAF 226 Query: 272 QKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVY 331 +GTVTA +S L+DGAAA+++M+ A+ L + P ARI + A +P PV Sbjct: 227 DPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVP 286 Query: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIK----MLEIDPQKVNINGGAVSLGHPI 387 A+ + LK GL DI ++E+NEAF+ +L IK M +ID +K+N+NGGA++LGHP+ Sbjct: 287 ASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQID-EKINLNGGAIALGHPL 345 Query: 388 GMSGARIVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 G SGARI L + + K ++GLA++C G G A + +++ Sbjct: 346 GCSGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV 387 >1WDK-C nrPDB Length = 390 Score = 188 bits (478), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 134/397 (33%), Positives = 209/397 (52%), Gaps = 20/397 (5%) Query: 40 KEVVIVSATRTPIGSFLGSLSL-LPATKLGSIAIQGAIEK-AGIPKEEVKEAYMGNVLQG 97 ++VVIV RTP+G G + A + + I +E+ + + EV++ G V Q Sbjct: 5 RDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQT 64 Query: 98 GE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM 156 E G R A L +P ++ T++++C S M A+ A+Q++M G+ DV V GG+E M Sbjct: 65 LEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHM 124 Query: 157 SNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 +V + P+ + G+ MG AE K I+R +QDA+A+ Sbjct: 125 GHVSMMHGVDPNPHMSLYAAK---ASGM--------MGLTAEMLGKMHGISREQQDAFAV 173 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYK-RVDFSKVPKLKTVFQKEN 275 S+ + A GKF +E+IP+ + + DE + + LK F + Sbjct: 174 RSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKG 233 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 GTVTA +S + DGA+ +++M+A AK L + PLA I + A A V+P PV A Sbjct: 234 GTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQK 293 Query: 336 VLKDVGLKKEDIAMWEVNEAF---SLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 LK GL DI E+NEAF +L VL ++K+L+ +KVN++GGA++LGHP G SGA Sbjct: 294 ALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGA 353 Query: 393 RIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 RI G L + +KQ G +GL+++C G G A + +++ Sbjct: 354 RISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFERV 390 >5ZQZ-B nrPDB Length = 474 Score = 186 bits (473), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 139/431 (32%), Positives = 207/431 (48%), Gaps = 45/431 (10%) Query: 34 VSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGN 93 ++KP ++ VV+V RTP S L L A+ G + + +PKE V G Sbjct: 46 LAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGT 105 Query: 94 VLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGM 153 V+Q + R+A LGAG TP T+ C S +A+ + G DV+VAGG+ Sbjct: 106 VIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGV 165 Query: 154 ESMSNVPYVMNR---------GSTPYGGVKLEDLIVK----------DGLTDVYNKIHMG 194 E MS+VP +R G +L LI K +++ MG Sbjct: 166 ELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLS-LISKFRFNFLAPELPAVSEFSTSETMG 224 Query: 195 SCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254 A+ A ++R EQD YA+ S++ +K A + G ++V+P V K D V K D Sbjct: 225 HSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK---DTVTK-DN 279 Query: 255 EYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVA 314 + ++ KLK F K GTVTAAN+S L DGA+A+++M + A + P A + Sbjct: 280 GIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRD 339 Query: 315 FADAAVEPID-FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDP-- 371 F + +P D + P YA VL+ GL DI +E +EAFS +LAN K ++ D Sbjct: 340 FMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFA 399 Query: 372 ---------------QKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICN 414 +K N GG++SLGHP G +G R+V + L++ G+YGL + C Sbjct: 400 ENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACA 459 Query: 415 GGGGASAMLIQ 425 GG AM+++ Sbjct: 460 AGGQGHAMIVE 470 >2IIK-A nrPDB Length = 418 Score = 181 bits (460), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 133/403 (33%), Positives = 217/403 (53%), Gaps = 20/403 (4%) Query: 31 RSYVSKPTLKEVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEA 89 +S + + +VV+V RT I + G +L S + ++ + E++ + Sbjct: 21 QSMAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDI 80 Query: 90 YMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMV 149 +GNVLQ G G R A + +P + P +T+N+ C+SG++A+ + + G D+ + Sbjct: 81 CVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGM 140 Query: 150 AGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 209 A G+ESMS + +RG+ G L+ K+ D I MG +EN A++ I+R Sbjct: 141 ACGVESMS----LADRGNP---GNITSRLMEKEKARDCL--IPMGITSENVAERFGISRE 191 Query: 210 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTV---KG-QPDVVVKEDEEYK-RVDFSKV 264 +QD +A+ S ++ A G F E++PVT TV KG + + V +DE + + Sbjct: 192 KQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL 251 Query: 265 PKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPID 324 KLK F+K+ G+ TA N+S ++DGAAA++L A+ L + L + ++A V P Sbjct: 252 AKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDI 310 Query: 325 FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLG 384 I P YA + L+ GL D+ ++E+NEAF+ ++ L + P+KVN GGAV+LG Sbjct: 311 MGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALG 370 Query: 385 HPIGMSGARIVGHLTHALKQ---GEYGLASICNGGG-GASAML 423 HP+G +GAR V L + LK+ YG+ S+C G G GA+A+ Sbjct: 371 HPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 413 >3SVK-A nrPDB Length = 407 Score = 181 bits (459), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 133/424 (31%), Positives = 208/424 (49%), Gaps = 59/424 (13%) Query: 40 KEVVIVSATRTPIGSFL-GSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG- 97 +E I A RTP G GSL+ + L + G +++ ++ E + +++ G Sbjct: 7 EEAFIYEAIRTPRGKQKNGSLTEVKPLNL----VVGLVDELRRRYPDLDETLISDMILGV 62 Query: 98 -----GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 152 +G R AVL AGLP +T +N+ CASG++A+ A+Q + G D+++AGG Sbjct: 63 VSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGG 122 Query: 153 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKL-----NIA 207 +ESMS VP + G+ TD +G + L + Sbjct: 123 VESMSRVPMGSDGGAWA---------------TDPETNYRIGFVPQGIGADLIATLEGFS 167 Query: 208 RNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVD--FSKVP 265 R + DAYA+ S ++ AAW G F V+PV + Q +V+ + +E+ R D + Sbjct: 168 REDVDAYALRSQQKAAAAWSGGYFAKSVVPV----RDQNGLVILDHDEHMRPDTTMEGLA 223 Query: 266 KLKTVF--------------------QKENGTVTAANASTLNDGAAALVLMTADAAKRLN 305 KLKT F +K N T N+S + DGAA +++ + A K Sbjct: 224 KLKTAFDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQG 283 Query: 306 VTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIK 365 +TP ARIVA A + +P+ P A VL GL +DI ++E+NEAF+ VVL K Sbjct: 284 LTPRARIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQK 343 Query: 366 MLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL--KQGEYGLASICNGGGGASAML 423 L I +K+N+NGGA+++GHP+G +GA I G + L + L ++C GGG A + Sbjct: 344 DLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATI 403 Query: 424 IQKL 427 I+++ Sbjct: 404 IERV 407 >4B3J-C nrPDB Length = 403 Score = 177 bits (450), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 130/419 (31%), Positives = 211/419 (50%), Gaps = 49/419 (11%) Query: 40 KEVVIVSATRTPIGSFL-GSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG- 97 +E I A RTP G GSL + L + G I++ ++ E + +V+ G Sbjct: 3 EEAFIYEAIRTPRGKQKNGSLHEVKPLSL----VVGLIDELRKRHPDLDENLISDVILGC 58 Query: 98 -----GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 152 +G R AVL +G+P+++ +N+ CASG++A+ A+Q + G D+++AGG Sbjct: 59 VSPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGG 118 Query: 153 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 212 +ESMS VP + G+ D++ + A+ A +R + D Sbjct: 119 VESMSRVPMGSDGGAMGLDPATNYDVMF----------VPQSIGADLIATIEGFSREDVD 168 Query: 213 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSK--VPKLKTV 270 AYA+ S ++ AW G F V+PV + Q +++ + +E+ R D +K + KLK Sbjct: 169 AYALRSQQKAAEAWSGGYFAKSVVPV----RDQNGLLILDHDEHMRPDTTKEGLAKLKPA 224 Query: 271 FQ--------------------KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLA 310 F+ K N T N+S + DGAA +++ +A A K +TP A Sbjct: 225 FEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRA 284 Query: 311 RIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEID 370 RIVA A + +P+ P A VL GL +DI ++E+NEAF+ VVL K L I Sbjct: 285 RIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIP 344 Query: 371 PQKVNINGGAVSLGHPIGMSGARIVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 +K+N+NGGA+++GHP+G +GA I+G + L + L ++C GGG A +I+++ Sbjct: 345 DEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIERV 403 >6ESQ-A nrPDB Length = 392 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 7/89 (7%) Query: 75 AIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVL---GAGL-PISTPCTTINKVCASGM 130 AI+ A + ++ Y+GN + GG A L AGL P+ PCT + CASG Sbjct: 33 AIKDANVDGGDIDAMYIGN-MSGGLFVGQEHIASLIADHAGLNPV--PCTRVEAACASGS 89 Query: 131 KAIMMASQSLMCGHQDVMVAGGMESMSNV 159 A+ A S+ GH DV++AGG+E M++V Sbjct: 90 LALRSAVLSVASGHHDVVLAGGVEKMTDV 118 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 76/188 (40%), Gaps = 54/188 (28%) Query: 278 VTAANASTLNDGAAALVLMTADAAKR------------------------------LNVT 307 +T + S ++DGA+AL++ AD A+ LN Sbjct: 201 LTLMHCSPVSDGASALIVCDADKAEEFAPKDEIIYIKASTQASDTIALHDREDMTTLNAA 260 Query: 308 PLARIVAFADAAVEPIDFPIAPVYAAS-----MVLKDVGLKKEDIAMWEVNEAFSLVVLA 362 +A A+ A + P +A V+ ++++D+G K+ +A ++ Sbjct: 261 KVASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKK-------GDAGKVIDEG 313 Query: 363 NIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGE------------YGLA 410 I++ D VN +GG + GH +G +G R VG L LKQ + YG+A Sbjct: 314 KIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGYGIA 373 Query: 411 SICNGGGG 418 + G GG Sbjct: 374 ANVGGTGG 381 >6HRV-A nrPDB Length = 421 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 83/366 (22%), Positives = 141/366 (38%), Gaps = 71/366 (19%) Query: 73 QGAIEKAGIPKEEVKEAYMGNVLQGGE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMK 131 Q A+ AGI +++A +G V GQ ++ +G+PI +N C++G Sbjct: 45 QRALADAGIKYSAIQQACVGYVYGDSTCGQRAIYHSLGLSGIPI----INVNNNCSTGST 100 Query: 132 AIMMASQSLMCGHQDVMVAGGMESM---SNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVY 188 A+ M Q + G D ++A G E M S M+R + P +E +I + GL V Sbjct: 101 ALFMGRQLIQGGLADCVLALGFEKMERGSLSSKYMDR-TNPMDK-HMEVMINRYGLAAVP 158 Query: 189 NKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDV 248 M N R + Y +K AW+ K P Sbjct: 159 AAPQMFG---------NAGREHMEKYGTKPEHFAKVAWKNHKHSTN----------NPYS 199 Query: 249 VVKEDEEYKRV-DFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVT 307 +++ ++V D KV + T+ Q +DGA A VL + +R + Sbjct: 200 QFQDEYSLEQVIDSRKVFEFLTLLQ----------CCPTSDGAGAAVLASESFVRRNGLE 249 Query: 308 PLA-RIVA----------FAD-AAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA 355 A IVA F + + ++ + + + + AA G+K D+ + E+++ Sbjct: 250 KKAVEIVAQEMVTDLSTTFEENSCMKMVGYDMTRL-AAERCYDTAGVKPSDVDVIELHDC 308 Query: 356 FSLVVLANIKMLEIDPQK------------------VNINGGAVSLGHPIGMSGARIVGH 397 FS L + L + P+ +N +GG +S GHP+G +G Sbjct: 309 FSANELITYEALGLCPEGKAGELIDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAE 368 Query: 398 LTHALK 403 L L+ Sbjct: 369 LCWQLR 374 >4BI9-A nrPDB Length = 454 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 30/161 (18%) Query: 282 NASTLNDGAAALVLMTADAAKRLNVTP----LARIVAFADAAVEPI-DFPIAPVYAASMV 336 + S ++DG AA++L + + ++L ++P L I + A AA D P SMV Sbjct: 270 DCSQVSDGGAAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMV 329 Query: 337 -----LKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ------------------K 373 L G+K E + + EV++ F++ L + L I Sbjct: 330 AARTALSMAGVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIP 389 Query: 374 VNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASI 412 VN GG +S GHP+G +G + V + +K GEY + +I Sbjct: 390 VNTGGGLLSFGHPVGATGVKQVLEVYRQMKGQCGEYQMKNI 430 >1OXH-A nrPDB Length = 430 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Query: 119 CTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVM 163 C +IN C+S AI A +S+ G QDVM+ GG E+ S P+ + Sbjct: 176 CKSINTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEA-SITPFAI 219 >5LNQ-A nrPDB Length = 457 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 28/150 (18%) Query: 282 NASTLNDGAAALVLMTADAAKRLNVTP----LARIVAFADAAVEPIDFP------IAPVY 331 + S ++DG A +VL + +++ ++P L I + A A + P Sbjct: 273 DCSQVSDGGAGVVLANEEGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQ 332 Query: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ------------------K 373 AA L +K D+ + EV++ F++ + + L I Sbjct: 333 AAQKALSMANIKPSDLNVAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIP 392 Query: 374 VNINGGAVSLGHPIGMSGARIVGHLTHALK 403 VN GG +S GHP+G +G + + + +K Sbjct: 393 VNTGGGLLSFGHPVGATGIKQIMEVYRQMK 422 >4YZO-A nrPDB Length = 373 Score = 35.8 bits (81), Expect = 0.034, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 8/79 (10%) Query: 314 AFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ- 372 AF A VE IDF A ++ + +L+ + + EDI +++ E + V+ + +D + Sbjct: 255 AFKKAKVERIDF--AELHDMATILEII--QSEDIGLFKKGEGWKAVMEG---LTSLDGEI 307 Query: 373 KVNINGGAVSLGHPIGMSG 391 +N +GG S GHPIG SG Sbjct: 308 PINPSGGLNSKGHPIGASG 326 >4JPF-A nrPDB Length = 436 Score = 34.7 bits (78), Expect = 0.075, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 24/42 (57%) Query: 113 LPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 L + P + C +G +I MA++++ G DVMVAGG E Sbjct: 173 LGLQGPNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 >3KZU-A nrPDB Length = 428 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 23/38 (60%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P ++ CA+G AI A++ + G DVMVAGG ES Sbjct: 170 PNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTES 207 >2IWZ-A nrPDB Length = 438 Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 28/154 (18%) Query: 21 RLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSF---LGSLSLLPATKLGSIAIQGAIE 77 R E ++ E+++VSK +K + S T IG+ + P ++ +A AI Sbjct: 73 RGSDEGQFNEQNFVSKSDIKS--MSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIG 130 Query: 78 KAGIPKEEVKEAYMGNVLQG----------------GEGQAPTRQAVLGAGLPISTPCTT 121 IP E V E + +G GQ R + G +ST CTT Sbjct: 131 MGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTT 190 Query: 122 INKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 G A+ + + + G DVMVAGG +S Sbjct: 191 -------GAHAVGDSFRFIAHGDADVMVAGGTDS 217 >5XTD-T nrPDB Length = 95 Score = 32.0 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + E++ + + +GG +LGHP Sbjct: 34 EVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHP 69 >3E60-A nrPDB Length = 424 Score = 31.6 bits (70), Expect = 0.66, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 24/41 (58%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 P ++ C++G AI A++ + G DVM+AGG ES N Sbjct: 166 PNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTESPIN 206 >4JGA-A nrPDB Length = 437 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 23/41 (56%) Query: 115 ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 S P T C++G AI A + + G+ DVM+AGG E+ Sbjct: 174 FSGPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA 214 >2IX4-A nrPDB Length = 431 Score = 31.6 bits (70), Expect = 0.69, Method: Compositional matrix adjust. Identities = 15/30 (50%), Positives = 20/30 (66%) Query: 126 CASGMKAIMMASQSLMCGHQDVMVAGGMES 155 CA+G +I A++ + G DVMVAGG ES Sbjct: 179 CATGAHSIGDATRMIQFGDADVMVAGGTES 208 >5GUP-F nrPDB Length = 123 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + E+ + ++ +GG +LGHP Sbjct: 61 EVNENFAIDLIAEQPVSEVGSRVISCDGGGGALGHP 96 >1J3N-A nrPDB Length = 408 Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 24/41 (58%) Query: 115 ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 + P +T+ CA+G A+ A + + G D+++AGG E+ Sbjct: 150 FTGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEA 190 >2GP6-A nrPDB Length = 434 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 8/51 (15%) Query: 105 RQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 R A G P+S CASG +AI A Q ++ G D + GG+E+ Sbjct: 174 RHAKAGVMTPVSA--------CASGAEAIARAWQQIVLGEADAAICGGVET 216 >3U0E-A nrPDB Length = 428 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 32/122 (26%), Positives = 45/122 (36%), Gaps = 32/122 (26%) Query: 65 TKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGL----------P 114 T IA+ AI AG+ +EEV G ++ G G TR V A + P Sbjct: 93 TAWNHIAMDQAIADAGLTEEEVSNERTGIIM--GSGGPSTRTIVDSADITREKGPKRVGP 150 Query: 115 ISTPCT--------------------TINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 + P +I+ CA+ I A + + G QD M AGG E Sbjct: 151 FAVPKAMSSTASATLATFFKIKGINYSISSACATSNHCIGNAYEMIQYGKQDRMFAGGCE 210 Query: 155 SM 156 + Sbjct: 211 DL 212 >6G2J-R nrPDB Length = 116 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + E++ + + +GG +LGHP Sbjct: 54 EVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHP 89 >5JP1-A nrPDB Length = 220 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 257 KRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFA 316 +R+D +P + V E V A S L DG L T D A+RL P A ++ FA Sbjct: 17 ERIDVDNLPSPQDVADPELPPVRAT--SWLLDGH--LRAYTDDLARRLRGEPNAHLLHFA 72 Query: 317 DAAV 320 D+ V Sbjct: 73 DSQV 76 >5M3K-C nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 5/79 (6%) Query: 82 PKE--EVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQS 139 P+E V Y G + G PT LG P T +T N C S + M Q Sbjct: 45 PREIQAVAYGYHGEGISEYGGLGPTISDALGIS-PAPTFMSTAN--CTSSSVSFQMGHQM 101 Query: 140 LMCGHQDVMVAGGMESMSN 158 + G D+++ GG E M++ Sbjct: 102 VASGEYDIVLCGGFEKMTD 120 >4JRH-A nrPDB Length = 417 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 P I+ C +G+ I A++ + G D MVAGG E S Sbjct: 159 PNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAEKAS 198 >4R8E-A nrPDB Length = 413 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 P +I C SG+ I A++ + DVMVAGG E S Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAS 195 >6QSP-A nrPDB Length = 406 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 103 PTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 P+R L L I P T++ C+S +AI+ + + G D + GG +++S +P Sbjct: 153 PSR--FLARYLAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMP 208 >2WV9-A nrPDB Length = 673 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 18/88 (20%) Query: 350 WEVNEAFSLVVLANIKMLEIDPQKVNING--------------GAVSLGHPIGMSGARIV 395 W++++ ++ V +++M+ ++P K IN GAVSL +PIG SG+ IV Sbjct: 137 WKLDQKWNGV--DDVQMIVVEPGKPAINVQTKPGIFKTAHGEIGAVSLDYPIGTSGSPIV 194 Query: 396 GHLTHALKQGEYGLASICNGGGGASAML 423 + G YG I G SA++ Sbjct: 195 NSNGEII--GLYGNGVILGNGAYVSAIV 220 >5W2O-A nrPDB Length = 439 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Query: 109 LGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 LGA + TP + C+SG +AI A + ++ G DV V GG+E Sbjct: 181 LGARAGVMTPVSA----CSSGSEAIAHAWRQIVMGDADVAVCGGVE 222 >5O31-R nrPDB Length = 96 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + ++ + ++ +GG +LGHP Sbjct: 34 EVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHP 69 >3HO9-A nrPDB Length = 427 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 P +I SG+ I A++ + G DVMVAGG E S Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAS 209 >4QAV-A nrPDB Length = 415 Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 P + C +G AI +++ + G D+MVAGG E Sbjct: 157 PSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAF---ADAAVEPIDFPIAPVYAASMVLKDVGL 342 + +GA LVL + AK+ A IV F +DA P A + LKD G+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 343 KKEDI 347 ED+ Sbjct: 293 NPEDV 297 >4LS7-A nrPDB Length = 426 Score = 28.1 bits (61), Expect = 7.4, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 119 CTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 CT CA+G +I A + + G DVMV GG E+ Sbjct: 172 CTVT--ACATGTNSIGDAFKVIQRGDADVMVTGGTEA 206 >4DDO-A nrPDB Length = 451 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 4/42 (9%) Query: 114 PISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P+ P T CA+ ++AI A + + G DV++AGG E+ Sbjct: 185 PLGCPVTA----CAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IBU-A nrPDB 550 e-157 4N44-A nrPDB 539 e-154 4E1L-A nrPDB 528 e-150 6BN2-A nrPDB 521 e-148 4DD5-A nrPDB 518 e-147 1NL7-A nrPDB 501 e-142 1WL4-A nrPDB 498 e-141 3SS6-A nrPDB 491 e-139 4O9A-A nrPDB 490 e-139 6ARG-A nrPDB 490 e-139 4WYS-A nrPDB 484 e-137 6BJA-A nrPDB 483 e-137 5XYJ-B nrPDB 482 e-137 6BJB-A nrPDB 480 e-136 1ULQ-A nrPDB 475 e-134 4C2K-A nrPDB 472 e-133 4NZS-A nrPDB 472 e-133 5LP7-H nrPDB 470 e-133 2IIK-A nrPDB 456 e-128 5CBQ-A nrPDB 450 e-127 1WDK-C nrPDB 449 e-127 2C7Y-A nrPDB 447 e-126 1PXT-A nrPDB 444 e-125 2WUA-A nrPDB 443 e-125 3GOA-A nrPDB 441 e-124 5ZQZ-B nrPDB 419 e-117 3SVK-A nrPDB 408 e-114 4B3J-C nrPDB 407 e-114 4UBW-A nrPDB 396 e-111 6HRV-A nrPDB 242 2e-64 6ESQ-A nrPDB 162 3e-40 4BI9-A nrPDB 136 2e-32 Sequences not found previously or not previously below threshold: 5LNQ-A nrPDB 142 2e-34 4YZO-A nrPDB 88 7e-18 5M3K-C nrPDB 78 8e-15 4U4E-A nrPDB 64 2e-10 3O04-A nrPDB 53 3e-07 5W2O-A nrPDB 51 1e-06 4R8E-A nrPDB 50 2e-06 4DFE-A nrPDB 50 2e-06 4QAV-A nrPDB 49 4e-06 1J3N-A nrPDB 49 5e-06 4X0O-A nrPDB 48 7e-06 4EWP-A nrPDB 48 8e-06 6QSP-A nrPDB 48 1e-05 4JPF-A nrPDB 46 3e-05 2EBD-A nrPDB 46 3e-05 3E60-A nrPDB 46 3e-05 2IX4-A nrPDB 46 3e-05 2GP6-A nrPDB 45 6e-05 4DDO-A nrPDB 45 7e-05 4NHD-A nrPDB 45 7e-05 3KZU-A nrPDB 45 9e-05 5BY7-A nrPDB 44 1e-04 2GQD-A nrPDB 44 1e-04 4LS7-A nrPDB 43 2e-04 5AB6-A nrPDB 43 3e-04 1MZJ-A nrPDB 43 3e-04 3IL7-A nrPDB 43 3e-04 1OXH-A nrPDB 42 5e-04 4JRH-A nrPDB 41 7e-04 6ESQ-I nrPDB 41 8e-04 4RYB-A nrPDB 41 9e-04 4YUC-A nrPDB 41 0.001 4JGA-A nrPDB 40 0.002 5BQS-A nrPDB 40 0.002 4V2P-A nrPDB 39 0.003 3IL4-A nrPDB 39 0.004 2IWZ-A nrPDB 38 0.005 3HO9-A nrPDB 38 0.007 3H76-A nrPDB 38 0.008 2AJ9-A nrPDB 38 0.009 1TQY-A nrPDB 37 0.013 1UB7-A nrPDB 37 0.014 3GWE-A nrPDB 36 0.022 6ET0-A nrPDB 36 0.028 4JD3-A nrPDB 36 0.036 4YLT-A nrPDB 35 0.050 1E5M-A nrPDB 35 0.056 5YO9-A nrPDB 35 0.067 5ENY-A nrPDB 35 0.087 4EFI-A nrPDB 34 0.11 2BZ4-A nrPDB 34 0.12 2Z0I-A nrPDB 34 0.12 3OA3-A nrPDB 34 0.13 4OQJ-A nrPDB 34 0.15 4XOX-A nrPDB 33 0.25 5BNS-A nrPDB 32 0.40 5LBT-A nrPDB 32 0.42 6G2J-R nrPDB 32 0.48 3IL3-A nrPDB 32 0.48 5XTD-T nrPDB 32 0.56 5O31-R nrPDB 32 0.60 5VXG-A nrPDB 32 0.63 5GUP-F nrPDB 32 0.63 3OYT-A nrPDB 31 0.70 2P1R-A nrPDB 31 0.72 2II1-A nrPDB 31 0.91 3VEW-A nrPDB 31 0.99 4KKD-A nrPDB 30 1.6 4IW4-E nrPDB 30 1.6 5MB9-A nrPDB 30 1.8 4HA6-A nrPDB 30 2.2 4ANI-C nrPDB 29 3.5 2X3E-A nrPDB 29 3.7 4COG-A nrPDB 29 4.5 2IVO-A nrPDB 29 5.1 3U0E-A nrPDB 28 6.0 6ET3-B nrPDB 28 6.1 5EP3-A nrPDB 28 7.1 5OQL-Y nrPDB 28 7.8 3ENO-A nrPDB 28 7.8 5EP0-A nrPDB 28 8.0 >2IBU-A nrPDB Length = 395 Score = 550 bits (1417), Expect = e-157, Method: Composition-based stats. Identities = 393/395 (99%), Positives = 393/395 (99%) Query: 33 YVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMG 92 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMG Sbjct: 1 MASKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMG 60 Query: 93 NVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 152 NVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG Sbjct: 61 NVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 120 Query: 153 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 212 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD Sbjct: 121 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 180 Query: 213 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 272 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ Sbjct: 181 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 240 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA Sbjct: 241 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 300 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA Sbjct: 301 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 360 Query: 393 RIVGHLTHALKQGEYGLASICNGGGGASAMLIQKL 427 RIVGHLTHALKQGEYGLASICNGGGGASAMLIQKL Sbjct: 361 RIVGHLTHALKQGEYGLASICNGGGGASAMLIQKL 395 >4N44-A nrPDB Length = 400 Score = 539 bits (1390), Expect = e-154, Method: Composition-based stats. Identities = 179/392 (45%), Positives = 252/392 (64%), Gaps = 5/392 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +KEVVI SA RT IGS+ SL +PA LG+ AI+ A++KAGI E+V E +GNVLQ G Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ P RQA AGLP+ P TINKVC SG++ + +A+Q + G DV++AGGME+MS Sbjct: 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120 Query: 159 VPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 PY+ N R G K D ++ DGL D +N HMG AEN A++ NI+R EQD +A+ Sbjct: 121 APYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFAL 180 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENG 276 S +++ A ++G+F +E++PV + + VV ++ + KLK F+K+ G Sbjct: 181 ASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKD-G 239 Query: 277 TVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV 336 TVTA NAS LND AA LV+M+A+ AK L V PLA+IV++ A V+P P YA Sbjct: 240 TVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAA 299 Query: 337 LKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVG 396 ++ G +++ + E NEAF+ LA K L+ D KVN+NGGA++LGHPIG SGARI+ Sbjct: 300 IEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILV 359 Query: 397 HLTHALKQ--GEYGLASICNGGGGASAMLIQK 426 L HA+++ + GLA++C GGG +A+L++K Sbjct: 360 TLVHAMQKRDAKKGLATLCIGGGQGTAILLEK 391 >4E1L-A nrPDB Length = 395 Score = 528 bits (1361), Expect = e-150, Method: Composition-based stats. Identities = 168/394 (42%), Positives = 244/394 (61%), Gaps = 6/394 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 +K+VVIVSA RTPIGSF G A +LG+IA++ AI + G+ E+ E +GNVLQ Sbjct: 3 AMKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQT 62 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 G GQ RQ + AG+P S P T+NK+C SG+K++ +A+QS+ G DV++AGG E+MS Sbjct: 63 GLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMS 122 Query: 158 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 PY++ R + G + + D ++ DGL D +N+ HMG AEN A K R QD A Sbjct: 123 QAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKLA 182 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVT-VKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 + S +++ A + +F E++PV V +G+ + + K++ + F + KLK F+K+ Sbjct: 183 LESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAFKKD 242 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS +NDGAA L+LM+ A L + PLA+I ++A A VEP P+ A Sbjct: 243 -GTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIPATR 301 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 LK GL DI + E NEAF+ LA L+ID K+N+NGGA++LGHPIG SGARI Sbjct: 302 KALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASGARI 361 Query: 395 VGHLTHALKQG--EYGLASICNGGGGASAMLIQK 426 + L + +++ E GLA++C GGG +M++ + Sbjct: 362 LVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR 395 >6BN2-A nrPDB Length = 401 Score = 521 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 225/392 (57%), Positives = 293/392 (74%), Gaps = 3/392 (0%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +KEV IVSA RTP+GSF+GSLS +PAT+LG++AI+GA++K + E+++ YMGNVLQ G Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAG 68 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 EGQAP +QA LGAGLP +TP T +NKVCASGMKA+MMA+Q++ G + +VAGGME+MS Sbjct: 69 EGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMSQ 128 Query: 159 VPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 217 VP+ ++ R G +KL+D ++KDGLTDVY+K HMG+CAE AK+ NI R EQDA+AI Sbjct: 129 VPHYIDGRNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDAFAIQ 188 Query: 218 SYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGT 277 SY RS AW GKF EV+PV++ + ++ EDEEYK V F ++P L TVFQKENGT Sbjct: 189 SYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVKFDRIPTLPTVFQKENGT 248 Query: 278 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVL 337 VTAANASTLNDGA+ALVLM+ + + L + PLA+IV++ADAA P F AP A + L Sbjct: 249 VTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKALPIAL 308 Query: 338 KDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGH 397 L DI +E NEAFS+V LAN K+L +D KVN+NGGAV+LGHP+G SG+RI+ Sbjct: 309 AKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGSRIIVT 368 Query: 398 LTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 L + LKQ +YG A+ICNGGGGASA++I+ + Sbjct: 369 LINVLKQNNAKYGAAAICNGGGGASAIVIENI 400 >4DD5-A nrPDB Length = 396 Score = 518 bits (1334), Expect = e-147, Method: Composition-based stats. Identities = 164/393 (41%), Positives = 241/393 (61%), Gaps = 5/393 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 ++EVVI SA RT +GSF G+ + A +LG A + AI++A I + + E+ +G VL Sbjct: 5 NMREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTA 64 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 G GQ RQ LGAG+P+ P TIN VC SG++++ MASQ + G D+M+ GG E+MS Sbjct: 65 GLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 158 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 PY++ R G D ++KDGL+D++N HMG AEN A++ NI R EQD A Sbjct: 125 MSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELA 184 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 + S +++ A GKF E++PV + + VV K++ K+ KL+ F+K+ Sbjct: 185 LASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAKLRPAFKKD- 243 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 GTVTA NAS +NDGAA LV+M + A+ L + PLA IV++ A V+P PV A Sbjct: 244 GTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVPATKK 303 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 L+ + EDI + E NEAF+ +A I+ L ID KVN+NGGA+++GHPIG SGARI+ Sbjct: 304 ALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSGARIL 363 Query: 396 GHLTHALKQ--GEYGLASICNGGGGASAMLIQK 426 L + +K+ + GLA++C GGG + +++++ Sbjct: 364 TTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR 396 >1NL7-A nrPDB Length = 392 Score = 501 bits (1290), Expect = e-142, Method: Composition-based stats. Identities = 163/393 (41%), Positives = 234/393 (59%), Gaps = 4/393 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 + +VI SA RT +GSF G+ + PA +LG+ I +E+AG+ EV E +G VL Sbjct: 1 STPSIVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPA 60 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 GEGQ P RQA + AG+P +N++C SG++A+ + Q + G ++VAGGMESMS Sbjct: 61 GEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMS 120 Query: 158 NVPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 P+ + RG G K+ D ++KDGLTD + HMG+ AEN AK+ ++R+EQDA+A+ Sbjct: 121 MAPHCAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAV 180 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENG 276 S +++AA + G+F +E++P V + V ++ + KL+ F KE G Sbjct: 181 ASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKE-G 239 Query: 277 TVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV 336 TVTA NAS LNDGAAA +LM+ A R + PL RIV++A V+P P+ A+ Sbjct: 240 TVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKA 299 Query: 337 LKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVG 396 L+ G K D+ + E NEAF+ A K L DP VN+NGGA+++GHPIG SGARI+ Sbjct: 300 LERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILN 359 Query: 397 HLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 L +K+ GLA++C GGG AM I+ L Sbjct: 360 TLLFEMKRRGARKGLATLCIGGGMGVAMCIESL 392 >1WL4-A nrPDB Length = 397 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 167/389 (42%), Positives = 239/389 (61%), Gaps = 4/389 (1%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101 VVIVSA RT IGSF G+L+ +P LGS I+ +++A + E+V E G+VL G GQ Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67 Query: 102 APTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY 161 P RQA +GAG+P S P + +C SG+KA+ +A QS+ G ++VAGGME+MS P+ Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127 Query: 162 VMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYT 220 + R G + L D I+ DGLTD ++ HMG AEN AKK ++R +QD A+ S Sbjct: 128 LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQN 187 Query: 221 RSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN-GTVT 279 R++ A +AG F E++PV V+ + V ++ + + KLK F + GTVT Sbjct: 188 RTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVT 247 Query: 280 AANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKD 339 ANAS +NDGAAA+VLM A + +TPLARIV+++ VEP I P+ A + Sbjct: 248 PANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTK 307 Query: 340 VGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLT 399 G ED+ ++E+NEAF+ V A +K L ++P+KVNI GGA++LGHP+G SG RI+ L Sbjct: 308 AGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLL 367 Query: 400 HALKQ--GEYGLASICNGGGGASAMLIQK 426 H L++ G+A++C GGG AM +Q+ Sbjct: 368 HTLERMGRSRGVAALCIGGGMGIAMCVQR 396 >3SS6-A nrPDB Length = 394 Score = 491 bits (1264), Expect = e-139, Method: Composition-based stats. Identities = 153/394 (38%), Positives = 229/394 (58%), Gaps = 6/394 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 + VVI +A R+PIG+F G+L + +L +Q A+++ G+ EV E +G+ +Q Sbjct: 3 AMHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQR 62 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 + R A L AG P + TI + C+SGM+AIM A+ + G +V+VAGG+E+MS Sbjct: 63 TDEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMS 122 Query: 158 NVPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 + PY + +R ++ D + + L D + I MG AEN ++ I R EQD A Sbjct: 123 SSPYALKQHRWGQRLQHGEIRDTVW-EVLEDPIHHIMMGETAENLVEQYEITREEQDEVA 181 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 + S+T + A E+G F ++++P+T+ + + V K++ + K+ LK F+K+ Sbjct: 182 LRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKD- 240 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 G+VTA NAS LNDG+A LVLM+ + AK + PLARIV ++ A V+P I P A Sbjct: 241 GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRK 300 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 L+ V ED + E+NEAF+ LA K L++D +KVN+NG V LGHPIG +GARI Sbjct: 301 GLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGARIT 360 Query: 396 GHLTHALKQG--EYGLASICNGGGGASAMLIQKL 427 L H LK+ E G+AS+C GGG A+ I+ L Sbjct: 361 VSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 394 >4O9A-A nrPDB Length = 398 Score = 490 bits (1262), Expect = e-139, Method: Composition-based stats. Identities = 178/391 (45%), Positives = 250/391 (63%), Gaps = 6/391 (1%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 +VVIVSA RT +G F GSL+ +PA +LG++ I+ A+E+AG+ E+V E MG VL G G Sbjct: 8 DVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSG 67 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 Q P RQA + AGLP P TINKV SG+KA+M+A+ ++M G +++VAGG E+MS P Sbjct: 68 QNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAP 127 Query: 161 YVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINS 218 +V+ R G KL D ++ DGL DVYN+ HMG AEN AK+ I R QD +A+ S Sbjct: 128 HVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVGS 187 Query: 219 YTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKENGT 277 +++AA +AGKF E++PV + + V K DE ++ + LK F K GT Sbjct: 188 QNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKA-GT 246 Query: 278 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVL 337 VTAANAS LNDGAAA+V+M+A AK L +TPLA I ++A+A V+P + PV A+ L Sbjct: 247 VTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRAL 306 Query: 338 KDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGH 397 +D+ + E+NEAF+ LA + + D KVN+NGGA+++GHPIG SG RI+ Sbjct: 307 SRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVT 366 Query: 398 LTHALKQ--GEYGLASICNGGGGASAMLIQK 426 L H +K+ + GLAS+C GGG A+ +++ Sbjct: 367 LLHEMKRRDAKKGLASLCIGGGMGVALAVER 397 >6ARG-A nrPDB Length = 399 Score = 490 bits (1262), Expect = e-139, Method: Composition-based stats. Identities = 194/396 (48%), Positives = 268/396 (67%), Gaps = 6/396 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKA-GIPKEEVKEAYMGNVLQ 96 +L V IVS+ RTP+GSFLGSLS L A +LG+ AI+ A+ K G+ +V+E + GNV+ Sbjct: 4 SLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVIS 63 Query: 97 GGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM 156 GQ P RQ LGAGL ST CTT+NKVCASG+KAI++ +Q++M G+ DV+VAGG ESM Sbjct: 64 ANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESM 123 Query: 157 SNVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SN P+ + R YG L D I+KDGLTD + MG AE A+ +R +QD Y Sbjct: 124 SNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEY 183 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTV-KGQPDVVVKEDEEYKRVDFSKVPKLKTVFQK 273 AI +Y +++AA +AG F E+ P+ + +G+PDV V +DEE K ++ K+ +K F Sbjct: 184 AIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIP 243 Query: 274 ENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAA 333 +GTVTA N+S LNDGAAA+VL++ K LN+ P+A+I+ + DAA +P F AP A Sbjct: 244 GSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAI 303 Query: 334 SMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGAR 393 LK G+ ++ I +E+NEAFS+V LAN+K+L I +KVN++GGAV++GHPIG SGAR Sbjct: 304 PKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGAR 363 Query: 394 IVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 I+ L L K+G+ G A ICNGGGGASA++++ L Sbjct: 364 ILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 399 >4WYS-A nrPDB Length = 405 Score = 484 bits (1247), Expect = e-137, Method: Composition-based stats. Identities = 175/395 (44%), Positives = 241/395 (61%), Gaps = 6/395 (1%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 +K VIVSA RT IGSF GSL+ A LG+ I+ AIE+A I + V E MGNVLQ Sbjct: 3 AMKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQA 62 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 G GQ P RQA+L +GL + T+NKVC SG+K++ +A+Q++ G +VAGGME+MS Sbjct: 63 GLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMS 122 Query: 158 NVPYVMN---RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 PY+++ R G ++ D+I++DGL + HMG AEN AK+ I R QD Sbjct: 123 LAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDEL 182 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 A++S ++ AA E+G F E++PV V + + V +++ + L+ F K Sbjct: 183 ALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKA 242 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS +NDGAAALV+M AA +TPLARI ++A V P + PV A Sbjct: 243 -GTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQ 301 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 L+ GL+ DI + E NEAF+ LA K L D +KVN+NGGA++LGHPIG SGARI Sbjct: 302 KALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARI 361 Query: 395 VGHLTHALKQGEY--GLASICNGGGGASAMLIQKL 427 + L HA++ + GLA++C GGG AM+I++L Sbjct: 362 LVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERL 396 >6BJA-A nrPDB Length = 397 Score = 483 bits (1243), Expect = e-137, Method: Composition-based stats. Identities = 195/389 (50%), Positives = 266/389 (68%), Gaps = 1/389 (0%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 K+V I+SA RTPI SF +L+ L A LG + + AI+++ +P ++E +GNVL G Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGL 68 Query: 100 GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNV 159 GQ RQ + + +P S+ C TINKVC+S MKAI+M +Q++ G++ ++VA G ESMSN Sbjct: 69 GQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNA 128 Query: 160 PYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSY 219 P+ + RG P+GGV+L D + +DGL D MG CAE T K R + DAYAI SY Sbjct: 129 PFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAIESY 188 Query: 220 TRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN-GTV 278 +++ AW+ G F EV+PV+V K VV+ EDEEYKR+ KVP L F K+ GT+ Sbjct: 189 RKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPAFLKDGSGTI 248 Query: 279 TAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLK 338 TAANAST+NDGAAA VL + + + + P+A+++++A+A VEPIDF +AP A +L Sbjct: 249 TAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAVKQLLS 308 Query: 339 DVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHL 398 GL +E IA+WE+NEAFS+ LA IK L +DP++VN+ GGAV+LGHP+G SGARIV L Sbjct: 309 QSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGARIVVTL 368 Query: 399 THALKQGEYGLASICNGGGGASAMLIQKL 427 HALK E G+A+ICNGGG ASA+LI+KL Sbjct: 369 VHALKSDELGVAAICNGGGEASAILIKKL 397 >5XYJ-B nrPDB Length = 408 Score = 482 bits (1242), Expect = e-137, Method: Composition-based stats. Identities = 191/396 (48%), Positives = 261/396 (65%), Gaps = 8/396 (2%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGI--PKEEVKEAYMGNVLQG 97 + V IVS RTPIGSF GSLS A +LG++A++GA+ K ++ E GNVL Sbjct: 13 QNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNVLSA 72 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 GQAP RQ L AGL +T+NKV AS MKAI++ +QS+ CG+ DV+VAGG ESM+ Sbjct: 73 NLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCESMT 132 Query: 158 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 N PY M R +G L D + +DGL D Y+ + MG AE A+ +I R +QD +A Sbjct: 133 NAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDNFA 192 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTV-KGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 I SY +S+ + + GKF NE++PVT+ +G+PD V +DEE R+ K+ +TVFQKE Sbjct: 193 IESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKE 252 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 NGTVTAANAS +NDGAAA++L++ K N+ PLA I + +AA +P DF AP A Sbjct: 253 NGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPSLAVP 312 Query: 335 MVLKDVGLK-KEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGAR 393 LK G++ + +E NEAFS+V L N K+L++DP KVN+ GGAV+LGHP+G SGAR Sbjct: 313 KALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGAR 372 Query: 394 IVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 +V L L+Q G+ G+A+ICNGGGGAS+++I+K+ Sbjct: 373 VVVTLLSILQQEGGKIGVAAICNGGGGASSIVIEKI 408 >6BJB-A nrPDB Length = 393 Score = 480 bits (1236), Expect = e-136, Method: Composition-based stats. Identities = 220/393 (55%), Positives = 280/393 (71%), Gaps = 3/393 (0%) Query: 35 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 94 S+P + +VV V A RTPIGSF + + +P T LG A++GA++ A + V+EA++G V Sbjct: 4 SRP-ITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVV 62 Query: 95 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 + GQ P RQ VLGAG +ST T +NK+ ASGMKAI A+ L Q+++VAGGME Sbjct: 63 VPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGME 122 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SMS VP+ + RG P+GG KL D I +DGL DVYN I MG+CA+ AK+ I R EQD Y Sbjct: 123 SMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKY 182 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 AI SY RS AAW+ G F E+IP+ VT +G+ + V+EDEEYK+V+F K+PKLK F E Sbjct: 183 AILSYKRSAAAWKEGIFAKEIIPLEVT-QGKKTITVEEDEEYKKVNFEKIPKLKPAFTSE 241 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 G+VTAANASTLNDGAA +V+ T D AK+ + PLAR++A+ DAA PIDF IAP Sbjct: 242 -GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIP 300 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 VLK GL+ +DI +WE+NEAF++V L +K L +D KVNI+GGAVSLGHPIGMSGARI Sbjct: 301 KVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARI 360 Query: 395 VGHLTHALKQGEYGLASICNGGGGASAMLIQKL 427 VGHL H LK G+ G A+ICNGGGGA M+I+KL Sbjct: 361 VGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 393 >1ULQ-A nrPDB Length = 401 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 152/402 (37%), Positives = 240/402 (59%), Gaps = 15/402 (3%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 + E IV A RTPIG G+L+ + L + A+ ++++G+PKEEV++ Y G Q G Sbjct: 1 MPEAWIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAG 60 Query: 99 E-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 E + R A+L AG P+ T+N++C SG++A+ A++++ G V + G+ESMS Sbjct: 61 EDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMS 120 Query: 158 NVPYVMNR--GSTPYGGVKLEDL-----IVKDGLTDVYNKIHMGSCAENTAKKLNIARNE 210 PY + + P G + + D V + +Y MG AEN A+ I R E Sbjct: 121 RAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRREE 180 Query: 211 QDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKT 269 QD +A+ S+ ++ AWE G+F +EV+PV V +G+ +++V++DE +R K+ L+ Sbjct: 181 QDRFALLSHQKAVRAWEEGRFQDEVVPVPVK-RGKEEILVEQDEGPRRDTSLEKLAALRP 239 Query: 270 VFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAP 329 VF +E GTVTA N+S LNDGAAA++L++ D AK + PLAR+ A A A V P I P Sbjct: 240 VF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGIGP 298 Query: 330 VYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKM--LEIDPQKVNINGGAVSLGHPI 387 V A L+ GL D+ + E+NEAF+ LA ++ L ++ Q++N NGGA++LGHP+ Sbjct: 299 VPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGHPL 358 Query: 388 GMSGARIVGHLTHALKQG--EYGLASICNGGGGASAMLIQKL 427 G SGARI+ L H +++ ++GLA++C G G A++++ + Sbjct: 359 GASGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVVEGM 400 >4C2K-A nrPDB Length = 417 Score = 472 bits (1214), Expect = e-133, Method: Composition-based stats. Identities = 158/393 (40%), Positives = 224/393 (56%), Gaps = 8/393 (2%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 L+ V +V+A RTP G++ G L AT L A + A+ + E V MGNVLQ Sbjct: 24 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 83 Query: 99 -EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 + R L G+P TP TIN++C SG ++I+ Q + +V++ GG ESMS Sbjct: 84 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 143 Query: 158 NVPYVMN--RGSTPYG-GVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 PY + R T G +KLED + LTD + ++ M AEN A K I+R E D Y Sbjct: 144 QAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKY 202 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 A+ S R KAA +AG F +E+ P+ V K + ++ + ++ KL VF+K+ Sbjct: 203 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 262 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GTVTA NAS + DGA A+++ + DA K+ N TPLARIV + + +P I PV A S Sbjct: 263 -GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAIS 321 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 LK GL +D+ + EVNEAF+ LA + L++D K N+NGGA++LGHP+G SG+RI Sbjct: 322 GALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 381 Query: 395 VGHLTHALKQ--GEYGLASICNGGGGASAMLIQ 425 HL H L++ G+Y + S C GGG A++IQ Sbjct: 382 TAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 414 >4NZS-A nrPDB Length = 399 Score = 472 bits (1214), Expect = e-133, Method: Composition-based stats. Identities = 152/393 (38%), Positives = 229/393 (58%), Gaps = 6/393 (1%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG- 98 +EVV+VS RT IG+F GSL + +LG++ ++ A+ +A + ++V GNV+Q Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 R A + G+ I+ P T+N++C SG++AI+ A+Q+++ G DV + GG ESMS Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 159 VPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 PY+ R G L D+++ L D +++IHMG AEN AK+ +I+R +QD A+ Sbjct: 128 APYLAPAARWGARMGDAGLVDMMLG-ALHDPFHRIHMGVTAENVAKEYDISRAQQDEAAL 186 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENG 276 S+ R+ AA +AG F ++++PV + ++ + KL+ VF KENG Sbjct: 187 ESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFVKENG 246 Query: 277 TVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV 336 TVTA NAS LND AAA+V+M A+R + PLAR+V++ A V+P I PV A + Sbjct: 247 TVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPATKIA 306 Query: 337 LKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVG 396 L+ GL+ D+ + E NEAF+ A K L +DP KVN NG +SLGHPIG +GA I Sbjct: 307 LERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGALITV 366 Query: 397 HLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 H L + G Y L ++C GGG A + +++ Sbjct: 367 KALHELNRVQGRYALVTMCIGGGQGIAAIFERI 399 >5LP7-H nrPDB Length = 393 Score = 470 bits (1210), Expect = e-133, Method: Composition-based stats. Identities = 166/392 (42%), Positives = 250/392 (63%), Gaps = 6/392 (1%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +++ VIVSA RTP G F G L + A +LG I ++ A+++AG+ ++V+ MG V+Q G Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 99 EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 GQ P+RQA AG+P S P T+NKVCASG++A+ + Q + D++VAGGMESMSN Sbjct: 61 SGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSN 120 Query: 159 VPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 +PY + R G +L DL+V DGLT ++++HM AK+ I+R EQD +A+ Sbjct: 121 IPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWAL 180 Query: 217 NSYTRSKAAWEAGKFGNEVIPVT-VTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 S+ R+ A + GKF +E++PV + KG+P+VV K++ + ++ KL ++ + Sbjct: 181 RSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPIYASD- 239 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 G++TA NA +NDGA A VLM+ + A L PLA I+ F+ + + AP +A + Sbjct: 240 GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGFAINK 299 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 395 +LK GL +DI ++EVNEAF+ VVL K++ D +KVN+NGGA++LGHPIG SGARI+ Sbjct: 300 LLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASGARIL 359 Query: 396 GHLTHALKQ--GEYGLASICNGGGGASAMLIQ 425 L + LK+ G G+A+IC+G A+L+Q Sbjct: 360 MTLVYELKRRGGGLGVAAICSGAAQGDAVLVQ 391 >2IIK-A nrPDB Length = 418 Score = 456 bits (1173), Expect = e-128, Method: Composition-based stats. Identities = 127/404 (31%), Positives = 209/404 (51%), Gaps = 19/404 (4%) Query: 31 RSYVSKPTLKEVVIVSATRTPIGSFL-GSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEA 89 +S + + +VV+V RT I G +L S + ++ + E++ + Sbjct: 21 QSMAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDI 80 Query: 90 YMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMV 149 +GNVLQ G G R A + +P + P +T+N+ C+SG++A+ + + G D+ + Sbjct: 81 CVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGM 140 Query: 150 AGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 209 A G+ESMS +RG+ G L+ K+ D I MG +EN A++ I+R Sbjct: 141 ACGVESMSLA----DRGN---PGNITSRLMEKEKARDCL--IPMGITSENVAERFGISRE 191 Query: 210 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDV-----VVKEDEEYKRVDFSKV 264 +QD +A+ S ++ A G F E++PVT TV V +++ + Sbjct: 192 KQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL 251 Query: 265 PKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPID 324 KLK F+K+ G+ TA N+S ++DGAAA++L A+ L + L + ++A V P Sbjct: 252 AKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDI 310 Query: 325 FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLG 384 I P YA + L+ GL D+ ++E+NEAF+ ++ L + P+KVN GGAV+LG Sbjct: 311 MGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALG 370 Query: 385 HPIGMSGARIVGHLTHALKQ---GEYGLASICNGGGGASAMLIQ 425 HP+G +GAR V L + LK+ YG+ S+C G G +A + + Sbjct: 371 HPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 414 >5CBQ-A nrPDB Length = 413 Score = 450 bits (1159), Expect = e-127, Method: Composition-based stats. Identities = 137/404 (33%), Positives = 213/404 (52%), Gaps = 15/404 (3%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQG 97 ++++ VI RTPIG + G L A LG A++G +E+ GI ++V++ +G+ Sbjct: 8 SMRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYPN 67 Query: 98 GEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 E A R L AGLPI+ P +++ C SG++A++ A + G D++VAGG ESMS Sbjct: 68 SEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESMS 127 Query: 158 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIH-----MGSCAENTAKKLNIARNE 210 NV + R GV++ D + + G T K H M AEN ++ +I+R E Sbjct: 128 NVAFYSTDMRWGGARTGVQIHDGLAR-GRTTAGGKFHPVPGGMLETAENLRREYHISRTE 186 Query: 211 QDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTV 270 QD A+ S+ R+ AA G E+IPV V + + + ++ + KLK V Sbjct: 187 QDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADTTVEALAKLKPV 246 Query: 271 FQKEN--GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIA 328 K++ TVTA N+S ND A+ ++ T + A L + PL R+V++ A V P I Sbjct: 247 LLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLMGIG 306 Query: 329 PVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLAN---IKMLEIDPQKVNINGGAVSLGH 385 PV A + L GL DI + E+NEAF+ LA K E D ++ N+ G +SLGH Sbjct: 307 PVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGISLGH 366 Query: 386 PIGMSGARIVGHLTHAL--KQGEYGLASICNGGGGASAMLIQKL 427 P+G +G R++ L L ++ YGL ++C GGG A + +++ Sbjct: 367 PVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVFERV 410 >1WDK-C nrPDB Length = 390 Score = 449 bits (1156), Expect = e-127, Method: Composition-based stats. Identities = 132/397 (33%), Positives = 203/397 (51%), Gaps = 20/397 (5%) Query: 40 KEVVIVSATRTPIGSFLGSLS-LLPATKLGSIAIQGAIEK-AGIPKEEVKEAYMGNVLQG 97 ++VVIV RTP+G G + A + + I +E+ + + EV++ G V Q Sbjct: 5 RDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQT 64 Query: 98 GE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM 156 E G R A L +P ++ T++++C S M A+ A+Q++M G+ DV V GG+E M Sbjct: 65 LEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHM 124 Query: 157 SNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 +V + P+ L MG AE K I+R +QDA+A+ Sbjct: 125 GHVSMMHGVDPNPHMS-----------LYAAKASGMMGLTAEMLGKMHGISREQQDAFAV 173 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE-EYKRVDFSKVPKLKTVFQKEN 275 S+ + A GKF +E+IP+ + + DE + LK F + Sbjct: 174 RSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKG 233 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 335 GTVTA +S + DGA+ +++M+A AK L + PLA I + A A V+P PV A Sbjct: 234 GTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQK 293 Query: 336 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEI---DPQKVNINGGAVSLGHPIGMSGA 392 LK GL DI E+NEAF+ L +K L++ +KVN++GGA++LGHP G SGA Sbjct: 294 ALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGA 353 Query: 393 RIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 RI G L + +KQ G +GL+++C G G A + +++ Sbjct: 354 RISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFERV 390 >2C7Y-A nrPDB Length = 404 Score = 447 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 130/398 (32%), Positives = 208/398 (52%), Gaps = 22/398 (5%) Query: 41 EVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 +VVIV+A RTP+ S G+ L + ++ IEK + EV + +G VL G Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 100 GQAP-TRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 +A R A AG P + T+N+ C+SG++A+ + ++ G D+ + G+ESM+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 159 VPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINS 218 P P VK + MG +EN A++ ++R EQD A++S Sbjct: 134 NPMAWEGSVNP---------AVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVDS 184 Query: 219 YTRSKAAWEAGKFGNEVIPVTV------TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 272 + ++ AA AGKF +E+IPV T +P V +D + + KLK VF+ Sbjct: 185 HRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVFK 244 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 K+ GT TA N+S ++DGA A++LM A + + L FA V+P I P A Sbjct: 245 KD-GTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVA 303 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 +K GL+ +DI ++E+NEAF+ + L +DP+K+N+NGGA+++GHP+G +GA Sbjct: 304 IPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 363 Query: 393 RIVGHLTHALKQ----GEYGLASICNGGGGASAMLIQK 426 R V L H +K+ +G+ S+C G G +A + ++ Sbjct: 364 RCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFER 401 >1PXT-A nrPDB Length = 390 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 128/390 (32%), Positives = 197/390 (50%), Gaps = 14/390 (3%) Query: 40 KEVVIVSATRTPIGS-FLGSLSLLPATKLGSIAIQGAIEKAGIPKEE----VKEAYMGNV 94 ++VVIV+A R+ IG F G+ + L + I + P ++E GNV Sbjct: 7 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 66 Query: 95 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 L G G R A L +G+P STP +N+ C+SG+ A+ + + G D+ +A G+E Sbjct: 67 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 126 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 SM+N + P G + E+L I MG EN A I+R +QD + Sbjct: 127 SMTNNYKNV----NPLGMISSEELQKNREAKKCL--IPMGITNENVAANFKISRKDQDEF 180 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 A NSY ++ A G F +E++P+ + + ++ V + ++ F K+ Sbjct: 181 AANSYQKAYKAKNEGLFEDEILPIKLPDG---SICQSDEGPRPNVTAESLSSIRPAFIKD 237 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 GT TA NAS ++DG A ++L A +LN+ L R + F V P + P YA Sbjct: 238 RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIP 297 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 VL+ GL+ +DI ++E+NEAF+ L I L ID KVN GGA++LGHP+G +GAR Sbjct: 298 KVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQ 357 Query: 395 VGHLTHALKQGEYGLASICNGGGGASAMLI 424 V + LK+ + G+ S+C G G +A + Sbjct: 358 VATILRELKKDQIGVVSMCIGTGMGAAAIF 387 >2WUA-A nrPDB Length = 440 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 131/398 (32%), Positives = 208/398 (52%), Gaps = 22/398 (5%) Query: 41 EVVIVSATRTPIGS-FLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 +VVIV+A R+P+ G L + + ++ IEK I EV + +G+VL G Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 100 GQAP-TRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 +A R A AG P + P T+N+ C+SG++A+ + ++ G D+ + G+ESM+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 159 VPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINS 218 P P VK + MG +EN A+K +I R EQD A+ S Sbjct: 154 NPMAWEGSVNPK---------VKTMAQAQDCLLPMGITSENVAQKFSITRQEQDQAAVGS 204 Query: 219 YTRSKAAWEAGKFGNEVIPVTV------TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQ 272 + ++ AA AG+F +E+IP+ T +P + +D + + KLK VF+ Sbjct: 205 HRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPVFR 264 Query: 273 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 332 K+ G+ TA +S ++DGA A++LM A + + L FA V P I P A Sbjct: 265 KD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAVA 323 Query: 333 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 +K GL+ +DI ++E+NEAF+ + K LEIDPQK+N+NGGA+++GHP+G +GA Sbjct: 324 IPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATGA 383 Query: 393 RIVGHLTHALKQ----GEYGLASICNGGGGASAMLIQK 426 R V L H +K+ +G+ S+C G G +A + ++ Sbjct: 384 RCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVFER 421 >3GOA-A nrPDB Length = 387 Score = 441 bits (1134), Expect = e-124, Method: Composition-based stats. Identities = 129/398 (32%), Positives = 206/398 (51%), Gaps = 20/398 (5%) Query: 39 LKEVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEK-AGIPKEEVKEAYMGNVLQ 96 +++VVIV A RTP+G S G+ + A L + ++ + + + + + Y G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 97 GGE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 E G R A L A +P S P T+N++C S M+A+ A++ +M G V + GG+E Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 156 MSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 M +VP GV + ++ MG AE ++ I+R QD +A Sbjct: 121 MGHVPMSH--------GVDFHPGLSRNVAKAAG---MMGLTAEMLSRLHGISREMQDQFA 169 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE-EYKRVDFSKVPKLKTVFQKE 274 S+ R+ AA ++G F E+IP DE + L+ F Sbjct: 170 ARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPV 229 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 334 +GTVTA +S L+DGAAA+++M+ A+ L + P ARI + A +P PV A+ Sbjct: 230 SGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASK 289 Query: 335 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDP---QKVNINGGAVSLGHPIGMSG 391 + LK GL DI ++E+NEAF+ +L IK L + +K+N+NGGA++LGHP+G SG Sbjct: 290 LALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSG 349 Query: 392 ARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 ARI L + +++ ++GLA++C G G A + +++ Sbjct: 350 ARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV 387 >5ZQZ-B nrPDB Length = 474 Score = 419 bits (1077), Expect = e-117, Method: Composition-based stats. Identities = 138/444 (31%), Positives = 209/444 (47%), Gaps = 45/444 (10%) Query: 21 RLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAG 80 R ++ + ++KP ++ VV+V RTP S L L A+ G + + Sbjct: 33 RAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTS 92 Query: 81 IPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSL 140 +PKE V G V+Q + R+A LGAG TP T+ C S +A+ + Sbjct: 93 VPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLI 152 Query: 141 MCGHQDVMVAGGMESMSNVPYVMNR---------GSTPYGGVKLEDLIVK---------- 181 G DV+VAGG+E MS+VP +R G +L LI K Sbjct: 153 ASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLS-LISKFRFNFLAPEL 211 Query: 182 DGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVT 241 +++ MG A+ A ++R EQD YA+ S++ +K A + G + V+P V Sbjct: 212 PAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP 270 Query: 242 VKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAA 301 K V +D + ++ KLK F K GTVTAAN+S L DGA+A+++M + A Sbjct: 271 GKD----TVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKA 326 Query: 302 KRLNVTPLARIVAFADAAVEPID-FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV 360 + P A + F + +P D + P YA VL+ GL DI +E +EAFS + Sbjct: 327 LAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQI 386 Query: 361 LANIKMLEIDP-----------------QKVNINGGAVSLGHPIGMSGARIVGHLTHALK 403 LAN K ++ D +K N GG++SLGHP G +G R+V + L+ Sbjct: 387 LANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLR 446 Query: 404 Q--GEYGLASICNGGGGASAMLIQ 425 + G+YGL + C GG AM+++ Sbjct: 447 KEGGQYGLVAACAAGGQGHAMIVE 470 >3SVK-A nrPDB Length = 407 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 133/419 (31%), Positives = 205/419 (48%), Gaps = 49/419 (11%) Query: 40 KEVVIVSATRTPIGSF-LGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKE-----AYMGN 93 +E I A RTP G GSL+ + L + G +++ ++ E +G Sbjct: 7 EEAFIYEAIRTPRGKQKNGSLTEVKPLNL----VVGLVDELRRRYPDLDETLISDMILGV 62 Query: 94 VLQGG-EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 152 V G +G R AVL AGLP +T +N+ CASG++A+ A+Q + G D+++AGG Sbjct: 63 VSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGG 122 Query: 153 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 212 +ESMS VP + G+ + G A+ A +R + D Sbjct: 123 VESMSRVPMGSDGGAWATDPETNYR----------IGFVPQGIGADLIATLEGFSREDVD 172 Query: 213 AYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR--VDFSKVPKLKTV 270 AYA+ S ++ AAW G F V+PV + Q +V+ + +E+ R + KLKT Sbjct: 173 AYALRSQQKAAAAWSGGYFAKSVVPV----RDQNGLVILDHDEHMRPDTTMEGLAKLKTA 228 Query: 271 FQ--------------------KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLA 310 F K N T N+S + DGAA +++ + A K +TP A Sbjct: 229 FDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRA 288 Query: 311 RIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEID 370 RIVA A + +P+ P A VL GL +DI ++E+NEAF+ VVL K L I Sbjct: 289 RIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIP 348 Query: 371 PQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 +K+N+NGGA+++GHP+G +GA I G + L++ L ++C GGG A +I+++ Sbjct: 349 DEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATIIERV 407 >4B3J-C nrPDB Length = 403 Score = 407 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 128/415 (30%), Positives = 208/415 (50%), Gaps = 41/415 (9%) Query: 40 KEVVIVSATRTPIGSF-LGSLSLLPATKLGSIAIQGAIEK-AGIPKEEVKEAYMGNVLQG 97 +E I A RTP G GSL + L I ++ + + + + +G V Sbjct: 3 EEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVSPV 62 Query: 98 G-EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM 156 G +G R AVL +G+P+++ +N+ CASG++A+ A+Q + G D+++AGG+ESM Sbjct: 63 GDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESM 122 Query: 157 SNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 S VP + G+ D++ + A+ A +R + DAYA+ Sbjct: 123 SRVPMGSDGGAMGLDPATNYDVMF----------VPQSIGADLIATIEGFSREDVDAYAL 172 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDF--SKVPKLKTVFQ-- 272 S ++ AW G F V+PV + Q +++ + +E+ R D + KLK F+ Sbjct: 173 RSQQKAAEAWSGGYFAKSVVPV----RDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGL 228 Query: 273 ------------------KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVA 314 K N T N+S + DGAA +++ +A A K +TP ARIVA Sbjct: 229 AALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVA 288 Query: 315 FADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKV 374 A + +P+ P A VL GL +DI ++E+NEAF+ VVL K L I +K+ Sbjct: 289 TATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKL 348 Query: 375 NINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL 427 N+NGGA+++GHP+G +GA I+G + L++ L ++C GGG A +I+++ Sbjct: 349 NVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIERV 403 >4UBW-A nrPDB Length = 399 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 136/403 (33%), Positives = 213/403 (52%), Gaps = 24/403 (5%) Query: 38 TLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKE----EVKEAYMGN 93 ++ VIV ATR+PIG G LS L AT+L + ++KAGI +V++ G Sbjct: 8 SMGYPVIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGC 67 Query: 94 VLQGGEG-QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 152 V Q GE +R A L AGLP TT++ C SG +A + + + G DV +A G Sbjct: 68 VTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACG 127 Query: 153 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 212 +E+MS V N G + + D+ N+ AE AK+ I R + D Sbjct: 128 IEAMSRVGLGANAGPDR------SLIRAQSWDIDLPNQF---EAAERIAKRRGITREDVD 178 Query: 213 AYAINSYTRSKAAWEAGKFGNEVIPVTVTV---KGQPDV---VVKEDEEYKRVDFSKVPK 266 + + S R++ AW G+F E+ P+ V + QP +V D+ + + + + Sbjct: 179 VFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMAGLGE 238 Query: 267 LKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFP 326 LK V E G TA +S ++DGAAA++ M A+ +TP ARIVA A EP Sbjct: 239 LKPVL--EGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHL 296 Query: 327 IAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 PV + + VL+ G+K DI + E+NEAF+ VVL+ ++ E D +VN+NGGA++LGHP Sbjct: 297 DGPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHP 356 Query: 387 IGMSGARIVGHLTHALKQGEYGLA--SICNGGGGASAMLIQKL 427 +G +G+R++ H L++ + LA ++C GG ++ +I+++ Sbjct: 357 VGCTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIERI 399 >6HRV-A nrPDB Length = 421 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 85/397 (21%), Positives = 147/397 (37%), Gaps = 73/397 (18%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG-EG 100 V ++ T + + A Q A+ AGI +++A +G V G Sbjct: 16 VFVIGVGMTKFEKPGA--RDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGDSTCG 73 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESM---S 157 Q ++ +G+PI +N C++G A+ M Q + G D ++A G E M S Sbjct: 74 QRAIYHSLGLSGIPI----INVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKMERGS 129 Query: 158 NVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 217 M+R + P +E +I + GL V M A R + Y Sbjct: 130 LSSKYMDR-TNPMDK-HMEVMINRYGLAAVPAAPQMFGNA---------GREHMEKYGTK 178 Query: 218 SYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRV-DFSKVPKLKTVFQKENG 276 +K AW+ K P +++ ++V D KV + T+ Q Sbjct: 179 PEHFAKVAWKNHKHSTN----------NPYSQFQDEYSLEQVIDSRKVFEFLTLLQ---- 224 Query: 277 TVTAANASTLNDGAAALVLMTADAAKRLNVTPLA-RIVAFA-----------DAAVEPID 324 +DGA A VL + +R + A IVA ++ ++ + Sbjct: 225 ------CCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEENSCMKMVG 278 Query: 325 FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQK----------- 373 + + + AA G+K D+ + E+++ FS L + L + P+ Sbjct: 279 YDMTRL-AAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRGDN 337 Query: 374 -------VNINGGAVSLGHPIGMSGARIVGHLTHALK 403 +N +GG +S GHP+G +G L L+ Sbjct: 338 TYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLR 374 >6ESQ-A nrPDB Length = 392 Score = 162 bits (410), Expect = 3e-40, Method: Composition-based stats. Identities = 93/429 (21%), Positives = 155/429 (36%), Gaps = 89/429 (20%) Query: 39 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 98 +++V I+ +T G L L A AI+ A + ++ Y+GN + GG Sbjct: 1 MRDVAIIGYGQTKFGE----LWEDSFRDLIVEAGVKAIKDANVDGGDIDAMYIGN-MSGG 55 Query: 99 EGQAPTRQAVL---GAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 A L AGL PCT + CASG A+ A S+ GH DV++AGG+E Sbjct: 56 LFVGQEHIASLIADHAGL-NPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGVEK 114 Query: 156 MSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215 M++V + ++ G T M A + + E ++ Sbjct: 115 MTDV----EDATAAIASASDQEWEAFFGATFPSLYAMM---ARRYMYQYGLTIEELSMWS 167 Query: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 275 + ++ + K + + +V V Sbjct: 168 VIAHENATK-------------------------NKYAQFGFKTTLEQVMNASPVADP-- 200 Query: 276 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIV--------AFADAAVEPIDFPI 327 +T + S ++DGA+AL++ AD A+ P I+ + A + D Sbjct: 201 --LTLMHCSPVSDGASALIVCDADKAEE--FAPKDEIIYIKASTQASDTIALHDREDMTT 256 Query: 328 --APVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQK------------ 373 A A+ K + E I + EV++ F++ L ++ L + Sbjct: 257 LNAAKVASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVIDEGKIR 316 Query: 374 --------VNINGGAVSLGHPIGMSGARIVGHLTHALKQGE------------YGLASIC 413 VN +GG + GH +G +G R VG L LKQ + YG+A+ Sbjct: 317 IDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGYGIAANV 376 Query: 414 NGGGGASAM 422 G GG + Sbjct: 377 GGTGGTVCV 385 >5LNQ-A nrPDB Length = 457 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 78/415 (18%), Positives = 139/415 (33%), Gaps = 74/415 (17%) Query: 42 VVIVSATRTPIGSFLGSL------------SLLPATKLGSIAIQGAIEKAGIPKEE--VK 87 V IV TP L + ++ + +QG +E +G+ E V Sbjct: 31 VFIVGGHITPFVGKGSPLFIDKKHPDFGKKKNMTLEEILATTVQGTMEHSGLSGREGIVD 90 Query: 88 EAYMGNVLQ---GGEGQ-APTRQAVLGAGLPIST------PCTTINKVCASGMKAIMMAS 137 + +GN L +G P L G S P + ASG A++ A Sbjct: 91 QVVVGNFLGELFSSQGHLGPAAIGSLTYGQAGSKNPLMYKPAMRVEGAAASGGLAVISAM 150 Query: 138 QSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCA 197 +L G D+ +A G+E + + + D + L D Sbjct: 151 NALKSGSADITLAVGVEVQTTASARVGGDYL----ARAADYQRQRQLDDFTFPCLFAKRM 206 Query: 198 ENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYK 257 + A+ + + A +Y A ++ + +V +E Y Sbjct: 207 KYIAEHNHFTMEDTARVAAKAYANGNKNPLAHMHTRKLTFEQCNGEDPSNVKFLGNETY- 265 Query: 258 RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTP----LARIV 313 KE +T + S ++DG A +VL + +++ ++P L I Sbjct: 266 ---------------KEYLRMT--DCSQVSDGGAGVVLANEEGLRKMGLSPNDSRLVEIK 308 Query: 314 AFADAAVEPIDFPI------APVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKML 367 + A A + P AA L +K D+ + EV++ F++ + + L Sbjct: 309 SIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLNVAEVHDCFTIAEMLMYEAL 368 Query: 368 EIDPQ------------------KVNINGGAVSLGHPIGMSGARIVGHLTHALKQ 404 I VN GG +S GHP+G +G + + + +K Sbjct: 369 GIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGATGIKQIMEVYRQMKG 423 >4BI9-A nrPDB Length = 454 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 95/458 (20%), Positives = 154/458 (33%), Gaps = 104/458 (22%) Query: 22 LVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSL------------SLLPATKLGS 69 LV ++ R S + K V +V T L +L + Sbjct: 10 LVPRGSHMLRRTSSTFSAKRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEELLA 69 Query: 70 IAIQGAIEKAGI---PKEEVKEAYMGNVLQ---GGEGQ-APTRQAVL---GAGLPISTPC 119 +I GA++ G+ V + +GN L +G P L + ++ P Sbjct: 70 ESINGALQNTGLHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNKPA 129 Query: 120 TTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLI 179 + CASG A+ A ++L+ G + +A G+E + V GG L Sbjct: 130 VRVEGACASGGLAVQSAWEALLAGTSQIALAVGVEVQTTVS-------ARVGGDYLAR-- 180 Query: 180 VKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD-AYAINSYTRSKAAWEAGKFGNEVI-- 236 A R D + R KA EAG F E Sbjct: 181 ---------------------AAHYKRQRQLDDFTFPCLFARRMKAIQEAGHFTMEDAAY 219 Query: 237 ------------PVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANAS 284 P+ + + K +F K + + S Sbjct: 220 VAAKAYASGNRNPLAHMHARKVTLDFCTQASDKNPNFLGNEIYKPFLRTTD-------CS 272 Query: 285 TLNDGAAALVLMTADAAKRLNVTP----LARIVAFADAAVEPI-DFPIAPVYAASM---- 335 ++DG AA++L + + ++L ++P L I + A AA D P SM Sbjct: 273 QVSDGGAAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMVAAR 332 Query: 336 -VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ------------------KVNI 376 L G+K E + + EV++ F++ L + L I VN Sbjct: 333 TALSMAGVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIPVNT 392 Query: 377 NGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASI 412 GG +S GHP+G +G + V + +K GEY + +I Sbjct: 393 GGGLLSFGHPVGATGVKQVLEVYRQMKGQCGEYQMKNI 430 >4YZO-A nrPDB Length = 373 Score = 88.1 bits (217), Expect = 7e-18, Method: Composition-based stats. Identities = 77/421 (18%), Positives = 135/421 (32%), Gaps = 92/421 (21%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101 V IV T G ++ L ++ EK + K ++ + N G Q Sbjct: 2 VAIVDVGITKFGKRKENIFDL---------VKEVTEK--LLKYDIDYVIVSNSYSGEFNQ 50 Query: 102 APTRQAVLGAGLP-ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 +++ L P ++ SG AI++A L + ++ G+E MS Sbjct: 51 TSGLSSLITTYLNLDYVPSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEKMSE-- 108 Query: 161 YVMNRGSTPYGGVKL---EDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 217 R T L E + L + +M +K N R A+ Sbjct: 109 -KKTREVTKIISSLLPFEERIASLPSLASISAIEYM--------RKFNAPRESIAQVAVK 159 Query: 218 SYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGT 277 ++ + + P KRV +V V + Sbjct: 160 NH-----------YNGSLNPFA--------------HIQKRVTLEEVLN-SPVISEPLRL 193 Query: 278 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVY- 331 + ++DGAAA+V++ + A P I + E DF P Sbjct: 194 Y---EYTPISDGAAAVVMVRNEDALSYTSKP-VYIKGIGSSNYTAYVSEKEDFVTLPAVV 249 Query: 332 -AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEI-----------------DPQ- 372 A+ K K E I E+++ +++ + + + + D + Sbjct: 250 EASRKAFKKA--KVERIDFAELHDMATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEI 307 Query: 373 KVNINGGAVSLGHPIGMSGARIVGHLT---------HALKQGEYGLASICNGGGGASAML 423 +N +GG S GHPIG SG +K GL+ G G ++ ++ Sbjct: 308 PINPSGGLNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSLSMAGYGNSATVI 367 Query: 424 I 424 I Sbjct: 368 I 368 >5M3K-C nrPDB Length = 398 Score = 78.1 bits (191), Expect = 8e-15, Method: Composition-based stats. Identities = 62/409 (15%), Positives = 122/409 (29%), Gaps = 90/409 (22%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE 99 + V IVSA TP S ++ + A++ A + E++ G Sbjct: 4 RRVAIVSAAYTP--KPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGY-----H 56 Query: 100 GQAPTRQAVLGAGLPIS-----TPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 G+ + LG + + P C S + M Q + G D+++ GG E Sbjct: 57 GEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFE 116 Query: 155 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 214 M++ + T+ +G DA+ Sbjct: 117 KMTDHFNYAEYIGSS---------------TECEYDYFLGIS-------------HTDAF 148 Query: 215 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 274 A+ + ++ + G G E V T Q + + ++ + + Sbjct: 149 ALAT---AEYFQKFGYAGRE-ADVLATFGRQMRIYAQNT-----PTATRYGQPIPSLEVL 199 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVE------------- 321 + + + + +L+ A + P + A V Sbjct: 200 KNSEACGSMLAWGEASGCAILVAEHLAHKYTDKP-VFVRGCAYTGVSHYFGTRFHNPTLH 258 Query: 322 ----PIDFPIA----PVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ- 372 P D +A + A + K G+ +DI + +V + L ++ + I + Sbjct: 259 HPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGA-GLIQMESMGICGKG 317 Query: 373 -----------------KVNINGGAVSLGHPIGMSGARIVGHLTHALKQ 404 +N +GG + GH G G + L L+ Sbjct: 318 QAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRG 366 >4U4E-A nrPDB Length = 383 Score = 63.8 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 60/376 (15%), Positives = 120/376 (31%), Gaps = 78/376 (20%) Query: 57 GSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGL-PI 115 G + PA L + A A+E+AG+ +V + G+ G+ P Sbjct: 20 GKVPDKPAIALHAEAALNALEEAGLTLRDVDGLLTAGISPLELGEYL--------GIEPS 71 Query: 116 STPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKL 175 T T + +S + + A+ +++ G V + ES R Sbjct: 72 YTDGTAVGG--SSFVIHLAHAAAAIVTGRCSVALITHGES--------GRSRVGMPPRVP 121 Query: 176 EDLIVKDGLTDVYNKI-HMGSCAENTAK---KLNIARNEQDAYAINSYTRSKAAWEAGKF 231 ++ D Y +G+ A ++ + + + A+ + + Sbjct: 122 APDSLRGQFEDPYGLPTPVGAYALACSRHMAEYGTTKEQLAEIAVAT-RKWAMLNPKAYM 180 Query: 232 GNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAA 291 + + V + + N + + D Sbjct: 181 RDPI------------------------TIEDVLNSRPIVWPFNLL----DCCLVTDAGG 212 Query: 292 ALVLMTADAAKRLNVTPLARIVAFADAAVEPID--FPIAPVYAASM----VLKDVGLKKE 345 A V+ + + A+ L P+A I+ ++ I P +AA K G+ + Sbjct: 213 ACVVTSIERARDLRQHPVA-ILGVGESHDHSIISQMPSLTSFAARRSGQAAFKMAGVTHD 271 Query: 346 DIAMWEVNEAFSLVVLANIKMLEIDPQ------------------KVNINGGAVSLGHPI 387 DI + + ++F+ VL +++ L + +N NGG +S HP Sbjct: 272 DIDLAMIYDSFTYTVLLSLEDLGFCAKGEGGAFVSGQRTAPGGDFPMNTNGGGLSYTHP- 330 Query: 388 GMSGARIVGHLTHALK 403 GM G + L+ Sbjct: 331 GMYGMFAIIEAVRQLR 346 >3O04-A nrPDB Length = 413 Score = 52.7 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 39/118 (33%), Gaps = 14/118 (11%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDV 340 + +GA ++L + AK A IV + P A M + D Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDA 290 Query: 341 GLKKEDIAMWEV-------NEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 GL + + N+ + + + +K+ I+ GH +G SG Sbjct: 291 GLTPDKVDYINAHGTSTPYNDEYETQAIKT--VFGEHAKKLAISSTKSMTGHTLGASG 346 >5W2O-A nrPDB Length = 439 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 47/133 (35%), Gaps = 23/133 (17%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 + A +++ T + AK PLAR++ + V P + A + L+ GL Sbjct: 264 EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGL 323 Query: 343 KKEDIAMWEVN----------EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 DI + EA ++ V + P+ +LGH IG GA Sbjct: 324 SPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKS--------ALGHSIGAVGA 375 Query: 393 RIVGHLTHALKQG 405 L+ G Sbjct: 376 LESVLTVLTLRDG 388 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 83 KEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMC 142 +V + ++ G Q AG + TP + C+SG +AI A + ++ Sbjct: 157 PRKVSPLAVQMIMPNGAAAVIGLQLGARAG--VMTPVSA----CSSGSEAIAHAWRQIVM 210 Query: 143 GHQDVMVAGGME 154 G DV V GG+E Sbjct: 211 GDADVAVCGGVE 222 >4R8E-A nrPDB Length = 413 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 42/117 (35%), Gaps = 10/117 (8%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDV 340 L DGA +VL + AK+ A +V F ++ P + A L+D Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 341 GLKKEDIAMWEVNEAFS-----LVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 G+ I + + A + D KV ++ GH +G +GA Sbjct: 292 GITTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGA 348 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTP 169 P +I C SG+ I A++ + DVMVAGG E S P + Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAST-PLGVGGFGAA 206 >4DFE-A nrPDB Length = 333 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 43/127 (33%), Gaps = 2/127 (1%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV RT I + + + + L IA Q AIE A I + + + Sbjct: 44 DEWIV--ARTGIHARYFAEPDVTTSDLAFIASQRAIEAADIDPQSIDLIIVATSTPDFVF 101 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 + G+ + VC+ A+ A + G + G E+ S + Sbjct: 102 PSTACLLQNKLGIRNHGAAFDVQAVCSGFAYAVATADSFIRSGQHRTALVIGAETFSRIL 161 Query: 161 YVMNRGS 167 +R + Sbjct: 162 DFKDRTT 168 >4QAV-A nrPDB Length = 415 Score = 49.2 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 43/114 (37%), Gaps = 8/114 (7%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFP---IAPVYAASMVLKDVGL 342 + +GA LVL + AK+ A IV F ++ P A + LKD G+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 343 KKEDIAMWEVNEAFSLVVLANI-----KMLEIDPQKVNINGGAVSLGHPIGMSG 391 ED+ + + + AN + K ++ GH +G +G Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAG 346 Score = 37.6 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 P + C +G AI +++ + G D+MVAGG E Sbjct: 157 PSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 Score = 28.0 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 52 IGSFLGSLSLLPATKLG-SIAIQGAIEKAGIPKEEVKEA 89 G + + + G ++A+ A++ AGI E+V Sbjct: 262 FGMSSDAYHITAPNEEGPALAVTRALKDAGINPEDVDYV 300 >1J3N-A nrPDB Length = 408 Score = 48.8 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 10/115 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GA LVL + AK+ A +V F +A EP A + LKD G+ Sbjct: 231 EGAGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDAGI 290 Query: 343 KKEDIAMWEVNEAFS-----LVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 E + + + VLA ++ +++ ++ +GH +G +GA Sbjct: 291 APEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGA 345 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 48/121 (39%), Gaps = 32/121 (26%) Query: 65 TKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG--------------QAPTR----- 105 + IA Q A+E AG+ E++ +G ++ G G + P R Sbjct: 72 VQYALIAAQLALEDAGLKPEDLDPERVGTLVGTGIGGMETWEAQSRVFLERGPNRISPFF 131 Query: 106 -----------QAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 + G + P +T+ CA+G A+ A + + G D+++AGG E Sbjct: 132 IPMMIANMASAHIAMRYGF--TGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTE 189 Query: 155 S 155 + Sbjct: 190 A 190 >4X0O-A nrPDB Length = 362 Score = 48.0 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 49/144 (34%), Gaps = 8/144 (5%) Query: 49 RTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAV 108 RT I +S + + L ++A Q AI AG+ EE+ + + Sbjct: 39 RTGIEQRR--ISHVNTSDLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLIPNIASRVQ 96 Query: 109 LGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNR--- 165 G+P S +N C + + A++ + H + G E +S R Sbjct: 97 QNLGIP-SAAAFDLNAACTGFLYGLETATRLMQASHYRHALVIGAERLSFYLDWTKRDTA 155 Query: 166 --GSTPYGGVKLEDLIVKDGLTDV 187 G V L K GL D Sbjct: 156 VLFGDGAGAVVLSKTEQKVGLQDA 179 >4EWP-A nrPDB Length = 350 Score = 48.0 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 40/111 (36%), Gaps = 1/111 (0%) Query: 49 RTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAV 108 RT I + + + + A + A+E+AG+ ++ + V + Sbjct: 47 RTGIVTRQRATAEETVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALVA 106 Query: 109 LGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNV 159 G P ++ CA + A + G ++ G+E +S+V Sbjct: 107 HEIG-ATPAPAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVERLSDV 156 >6QSP-A nrPDB Length = 406 Score = 47.7 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 40/99 (40%), Gaps = 10/99 (10%) Query: 113 LPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGG 172 L I P T++ C+S +AI+ + + G D + GG +++S +P + Sbjct: 161 LAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMPI------NGFDS 214 Query: 173 VKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 211 ++ + L + + + G + L + R Q Sbjct: 215 LES----LSPTLCEPFCQDRQGITIGEASTLLLLTREPQ 249 Score = 31.1 bits (69), Expect = 0.91, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 36/102 (35%), Gaps = 23/102 (22%) Query: 261 FSKVPKLKTV----FQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFA 316 F + L F ++ +T ASTL L+L P+A ++ Sbjct: 212 FDSLESLSPTLCEPFCQDRQGITIGEASTL------LLLTREP-------QPIA-LLGVG 257 Query: 317 DAA-----VEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN 353 +++ P + A +M L+ G+ +I ++ Sbjct: 258 ESSDAWHMSAPHPEGRGAIAAINMALRKAGISPAEIGYINLH 299 >4JPF-A nrPDB Length = 436 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 41/118 (34%), Gaps = 12/118 (10%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAA------VEPIDFPIAPVYAASMVLKD 339 L+DG+ ALVL + A+ A +V F + P D L+D Sbjct: 254 LSDGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPED-GAGAARCMKNALRD 312 Query: 340 VGLKKEDIAMWEVNEAFS-----LVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 392 GL + + + + A + ++++ GH +G +GA Sbjct: 313 AGLDPRQVDYINAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGA 370 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 P + C +G +I MA++++ G DVMVAGG E Sbjct: 178 PNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 >2EBD-A nrPDB Length = 309 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 70/206 (33%), Gaps = 20/206 (9%) Query: 28 YVERSYVSKPTLKEVVIVS----ATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPK 83 Y+ ++ ++ L+++V S TRT I + T + + A + A+ +A + Sbjct: 11 YLPKNVLTNFDLEKIVDTSDEWITTRTGIKERRIA-KEETITYMATQAAKEALREANLSP 69 Query: 84 EEVKEAYMGNVLQGGEGQAPT--RQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLM 141 EE+ + + + QA L A I+ C+ + A+ +A + Sbjct: 70 EELDLIILATLTPQKRFPSTACLVQAQLKA---KGVYAFDISAACSGFIYALDIADSFIK 126 Query: 142 CGHQDVMVAGGMESMSNVPYVMNRGS-TPYGGVKLEDLIVKDGLTDVYNKIHM------- 193 G ++ G E +S +R + +G ++ + M Sbjct: 127 SGKAKNVLVIGAEKLSEAVDWEDRSTCVLFGDGAGAVVVTRSEDKSDILATRMYAEGSLE 186 Query: 194 -GSCAENTAKKLNIARNEQDAYAINS 218 A+N R A+ S Sbjct: 187 ELLHADNCGYIRMKGRE-LFKVAVRS 211 Score = 32.6 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 13/99 (13%) Query: 334 SMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGAR 393 VL+ G+K E++++ ++A ++ A + L I +KV +N + G + A Sbjct: 217 REVLEKAGVKPEEVSLVIPHQANVRIINALAEKLNIPKEKVFVN---IQK---YGNTSAA 270 Query: 394 IVGHLTHA------LKQGEYGLASICNGGGGASAMLIQK 426 + H +K+G+ L + GGG ++ + Sbjct: 271 SIPIALHEAIKEGKVKRGDLILMTA-MGGGLTWGAVLLR 308 >3E60-A nrPDB Length = 424 Score = 45.7 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 23/38 (60%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P ++ C++G AI A++ + G DVM+AGG ES Sbjct: 166 PNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 Score = 45.0 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 41/107 (38%), Gaps = 9/107 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GAA +VL + AK+ A I+ + + P + + LK + Sbjct: 245 EGAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRAQV 304 Query: 343 KKEDIAMWEVNE----AFSLVVLANIKMLEIDPQKVNINGGAVSLGH 385 ++ + A + + A ++L +V+++ S+GH Sbjct: 305 NVSELDYINAHGTSTMADVIELAAVERVLGYYAPQVSMSSTKSSIGH 351 >2IX4-A nrPDB Length = 431 Score = 45.7 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 42/123 (34%), Gaps = 20/123 (16%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAA------VEPIDFPIAPVYAASMVLKD 339 + +G+ +VL + AKR A + + + P D V A + L+ Sbjct: 248 IGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPED-GKGAVLAMTRALRQ 306 Query: 340 VGLKKEDIAMWEVN----------EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGM 389 GL I + EA ++ + + + G + GH +G Sbjct: 307 SGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKG---ATGHLLGA 363 Query: 390 SGA 392 +GA Sbjct: 364 AGA 366 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 6/52 (11%) Query: 106 QAVLGAGL--PISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 + G P T CA+G +I A++ + G DVMVAGG ES Sbjct: 161 HVSMKYGFQGPNHAAVTA----CATGAHSIGDATRMIQFGDADVMVAGGTES 208 >2GP6-A nrPDB Length = 434 Score = 45.0 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 8/113 (7%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +G A L++ T + AK LARI+ + + V P +A + ++ GL Sbjct: 258 EGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGL 317 Query: 343 KKEDIAMWEVNEAFSLVV-LANIKMLE--IDPQKVNINGGAVSLGHPIGMSGA 392 DI + + V LA + + + + + +LGH +G GA Sbjct: 318 APGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYAPKSALGHSVGAVGA 370 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 8/59 (13%) Query: 96 QGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 R A G P+S CASG +AI A Q ++ G D + GG+E Sbjct: 165 GAAAAVGLERHAKAGVMTPVSA--------CASGAEAIARAWQQIVLGEADAAICGGVE 215 >4DDO-A nrPDB Length = 451 Score = 45.0 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 49/131 (37%), Gaps = 17/131 (12%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAP------VYAASMVLKDVG 341 +GAA +V+ + D A P+A I+ + A + P + A + L+ Sbjct: 264 EGAAMVVVESLDHALARGARPIAEIIGYGTTA-DAYHMTAGPDDGSGAMRAMKLALRMGD 322 Query: 342 LKKEDIAMWEVN-------EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 394 + E + + +A + L + + P I+ + GH +G +GA Sbjct: 323 VAPEQVDYVNAHATSTPVGDAGEIEALKTVFGVGAGPA---ISSTKSATGHLLGAAGAIE 379 Query: 395 VGHLTHALKQG 405 AL+ G Sbjct: 380 AAFSILALRDG 390 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 8/44 (18%) Query: 112 GLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 G P++ CA+ ++AI A + + G DV++AGG E+ Sbjct: 187 GCPVTA--------CAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 >4NHD-A nrPDB Length = 319 Score = 45.0 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 42/118 (35%), Gaps = 3/118 (2%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV RT I + + A Q AI AGI K ++ + Sbjct: 33 DEWIV--ARTGIRERRIAADNETVADMAFFAAQNAINMAGIDKHDIDMIIVATTSASHTF 90 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 + Q G+ P + C+ M A+ +A Q + G ++ G +++S Sbjct: 91 PSAACQVQGKLGI-KGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGADALSK 147 >3KZU-A nrPDB Length = 428 Score = 44.6 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 17/38 (44%), Positives = 23/38 (60%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P ++ CA+G AI A++ + G DVMVAGG ES Sbjct: 170 PNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTES 207 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 40/107 (37%), Gaps = 9/107 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GA +VL + A A ++ + + P + LK G+ Sbjct: 249 EGAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRAGI 308 Query: 343 KKEDIAMWEVNE----AFSLVVLANIKMLEIDPQKVNINGGAVSLGH 385 ++I + A ++ + A +++ K++++ S+GH Sbjct: 309 VPDEIDYINAHGTSTMADTIELGAVERVVGEAAAKISMSSTKSSIGH 355 >5BY7-A nrPDB Length = 360 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 29/87 (33%), Gaps = 1/87 (1%) Query: 66 KLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKV 125 L A A++ AG+ EEV +G G+ P + Sbjct: 83 DLAHQAGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGI-DGVPAYQLQSG 141 Query: 126 CASGMKAIMMASQSLMCGHQDVMVAGG 152 C+ ++A+ + L+ G + G Sbjct: 142 CSGAVQALAVTRSLLLGGTARTALVLG 168 Score = 28.4 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 29/90 (32%), Gaps = 13/90 (14%) Query: 332 AASMVLKDVGLKKEDIAMWEVNEA-----FSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 A S L G+ E++ + + A L ID G + Sbjct: 88 AGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGID--------GVPAYQLQ 139 Query: 387 IGMSGARIVGHLTHALKQGEYGLASICNGG 416 G SGA +T +L G ++ GG Sbjct: 140 SGCSGAVQALAVTRSLLLGGTARTALVLGG 169 >2GQD-A nrPDB Length = 437 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 40/114 (35%), Gaps = 10/114 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GA LV+ + ++A+ A IV + P A + D G+ Sbjct: 257 EGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGI 316 Query: 343 KKEDIAMWEVNEAFSLV-----VLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 + +D+ + + V V A + + ++ GH +G +G Sbjct: 317 EPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATG 370 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 8/77 (10%) Query: 125 VCASGMKAIMMASQSLMCGHQDVMVAGGME----SMSNVPYVMNRGSTPYGGVKLEDLIV 180 CA+G +I A + + G D M+ GG E M+ + +R + ++ Sbjct: 187 ACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPF 246 Query: 181 KDGLTDVYNKIHMGSCA 197 ++G + MG A Sbjct: 247 QEGR----DGFVMGEGA 259 >4LS7-A nrPDB Length = 426 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 36/114 (31%), Gaps = 10/114 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GA +VL + A IV + P A +KD G+ Sbjct: 246 EGAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDGEGGARAMQEAIKDAGI 305 Query: 343 KKEDIAMWEVNEAFS-----LVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 E+I + + +A + K+ ++ GH +G +G Sbjct: 306 APEEIDYINAHGTSTYYNDKYETMAIKTVFGEHAHKLAVSSTKSMTGHLLGAAG 359 Score = 36.5 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 113 LPISTPCTTINK----VCASGMKAIMMASQSLMCGHQDVMVAGGMES----MSNVPYVMN 164 + I+ +N CA+G +I A + + G DVMV GG E+ MS + N Sbjct: 160 ISIALGAKGVNSCTVTACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGFSAN 219 Query: 165 RG 166 + Sbjct: 220 KA 221 Score = 29.9 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 19/40 (47%), Gaps = 3/40 (7%) Query: 53 GSFLGSLSLLPAT---KLGSIAIQGAIEKAGIPKEEVKEA 89 GS + + + G+ A+Q AI+ AGI EE+ Sbjct: 274 GSTGDAYHITAPAQDGEGGARAMQEAIKDAGIAPEEIDYI 313 >5AB6-A nrPDB Length = 425 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 58/397 (14%), Positives = 114/397 (28%), Gaps = 98/397 (24%) Query: 42 VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101 V IV RT IG S +L + A++ A+ A + + +++ L + Sbjct: 22 VRIVGVGRTGIGKLHKS-----VDELAASALKCALVDANMKQCDLQALIAVPSLASPQFM 76 Query: 102 APTRQAVLGAGLPI--STPCTTINKVCASGMKAIMMASQSLMCGHQD---VMVAGGMESM 156 A + P T++ A + A+ MA + + V+ A + SM Sbjct: 77 QAHHIATVAGLFPTKGKFIVRTVDTGGAGPITALGMAVDLVRTRCAETVAVIAADAVLSM 136 Query: 157 SNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAI 216 + + R + + + + Y++ + ++R Y + Sbjct: 137 GSGAF-AERSNASL----RRSGLPEPCIPHGYDRY----------AQWYMSR-----YGL 176 Query: 217 NSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQK--E 274 + ++PV ++ K E + K L V Sbjct: 177 KREQLA------------MVPV---------LMSKMAERHPEAMCQKAYTLDEVLHSRCV 215 Query: 275 NGTVTAANASTLNDGAAALVLMTADAAKRL------------NVTPLARIVAFADAAVEP 322 + DGA AL++ P+ VA A + P Sbjct: 216 APVTNLLECARRADGAVALIVSGEAHYAEHFAQGKQEQRHLGGSKPIIASVAEASGPLFP 275 Query: 323 IDFPIAPVY-------AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQ--- 372 V AA L DI + + + F + ++ ++ + + P+ Sbjct: 276 PGSSDDIVPDIFSCRHAARDAFLSANLNVGDIHFFGLYDCFPICLIQAVEAVGLCPEGKG 335 Query: 373 -----------------------KVNINGGAVSLGHP 386 +N +GG G P Sbjct: 336 GEFMETAYNEMLNNGGVLDPSKFPINTHGGLQCFGAP 372 >1MZJ-A nrPDB Length = 339 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 48/123 (39%), Gaps = 9/123 (7%) Query: 48 TRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGN----VLQGGEGQAP 103 TRT I S + +G A + A+E AG+ E+ + V A Sbjct: 44 TRTGIRSRRIAEPDETIQVMGVAASRRALEHAGVDPAEIDLVVVSTMTNFVHTPPLSVAI 103 Query: 104 TRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVM 163 + LGA + ++ CA A+ +A+ ++ G ++ E M++V + Sbjct: 104 AHE--LGA---DNAGGFDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDVIDLA 158 Query: 164 NRG 166 +R Sbjct: 159 DRS 161 >3IL7-A nrPDB Length = 313 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 35/105 (33%), Gaps = 5/105 (4%) Query: 66 KLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAV--LGAGLPISTPCTTIN 123 L A AI AGI E++ + LG G Sbjct: 53 DLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTG---KVASMDQL 109 Query: 124 KVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGST 168 C+ M +++ A Q + G ++ G + +S + + +R + Sbjct: 110 AACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTA 154 Score = 31.5 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 17/88 (19%) Query: 324 DFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQK----VNINGG 379 A++ V++ L +DI ++ ++A ++ + + L I K VN G Sbjct: 213 IMGD----ASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGN 268 Query: 380 AVSLGHPIGMSGARIVGHLTHALKQGEY 407 S A I + LK G+ Sbjct: 269 T---------SAASIPLSIDQELKNGKL 287 >1OXH-A nrPDB Length = 430 Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 45/200 (22%), Positives = 62/200 (31%), Gaps = 51/200 (25%) Query: 119 CTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDL 178 C +IN C+S AI A +S+ G QDVM+ GG E+ S P+ + ED Sbjct: 176 CKSINTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEA-SITPFAIAGFQALTALSTTEDP 234 Query: 179 IVKDGLTDV-YNKIHMGSCAENT-------AKKLNIA--------RNEQDAYAINSY--- 219 D N MG + A+K N DAY + S Sbjct: 235 TRASIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPE 294 Query: 220 -TRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTV 278 + A + E+ P V + +GT Sbjct: 295 GQGAIKAIKLALEEAEISPEQV-----------------------------AYVNAHGTS 325 Query: 279 TAANASTLNDGAAALVLMTA 298 T AN + GA VL Sbjct: 326 TPANEKGES-GAIVAVLGKE 344 >4JRH-A nrPDB Length = 417 Score = 41.5 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 44/132 (33%), Gaps = 15/132 (11%) Query: 286 LNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDV 340 L DGA +VL + AK A +V F + P + A ++D Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 341 GLKKEDIAMWEVNEAFS-----LVVLANIKMLEIDPQK-VNINGGAVSLGHPIGMSGAR- 393 G+ E I + + V + L K V ++ GH +G +G+ Sbjct: 295 GVTGEQIGYVNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVE 354 Query: 394 ---IVGHLTHAL 402 V L + Sbjct: 355 AIITVMSLVDQM 366 Score = 41.5 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 29/130 (22%) Query: 68 GSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ----APTRQAVLGAG----LPISTPC 119 G A A+E +G+ E A +G + G G QA++ G P P Sbjct: 81 GIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALIEKGPRKVSPFFVPS 140 Query: 120 TTINKV--------------------CASGMKAIMMASQSLMCGHQDVMVAGGMESMSNV 159 T +N + C +G+ I A++ + G D MVAGG E S Sbjct: 141 TIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAEKAST- 199 Query: 160 PYVMNRGSTP 169 P M Sbjct: 200 PLGMAGFGAA 209 >6ESQ-I nrPDB Length = 349 Score = 41.5 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 47/136 (34%), Gaps = 5/136 (3%) Query: 60 SLLPATK-----LGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLP 114 +P+ + A + A+++AGI E++ Y+G+ + + G Sbjct: 43 KSVPSPDEDTATIAVEAARNAVKRAGINAEKIGAVYVGSESHPYAVKPTSATVAEAIGAT 102 Query: 115 ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVK 174 + C +G I M + G + +A G ++ P + GG Sbjct: 103 PDLTAADLEFACKAGTAGIQMCMGLVGSGLIEYGMAIGADTAQGAPGDALEYTASAGGAA 162 Query: 175 LEDLIVKDGLTDVYNK 190 KD + V+N Sbjct: 163 YIIGNKKDEMIAVFNG 178 >4RYB-A nrPDB Length = 320 Score = 41.1 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 30/88 (34%) Query: 80 GIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQS 139 G+ E+ + + + G+ P + VCA M A+ A+ Sbjct: 68 GLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAY 127 Query: 140 LMCGHQDVMVAGGMESMSNVPYVMNRGS 167 + G + G E+ S + +R + Sbjct: 128 IKSGMAKNALVIGAETFSRIVDWNDRTT 155 Score = 31.9 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 37/108 (34%), Gaps = 21/108 (19%) Query: 288 DGAAALVLMTADA---------AKRLNVTPLAR--IVAFADAAVEPIDFPIAPV---YAA 333 DGA A+VL AD A + L +A + P P +A Sbjct: 161 DGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAV 220 Query: 334 SM-------VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKV 374 M V+++ G I ++A ++ + K L + KV Sbjct: 221 KMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKV 268 >4YUC-A nrPDB Length = 335 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 58 SLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAY--MGNVLQGGEGQAPTRQAVLGAGLPI 115 + A+ +G+ A + A+ AG+ E++ G+ Q P Q LG G Sbjct: 52 WVKDETASFMGAEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGLGRS- 110 Query: 116 STPCTTINKVCASGMKAIMMASQ 138 P T+N C S A+ +A+ Sbjct: 111 GVPSITVNASCLSFFVALDVAAN 133 >4JGA-A nrPDB Length = 437 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 41/115 (35%), Gaps = 10/115 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +GA +VL + A ++ + P A + D + Sbjct: 256 EGAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAMLDATI 315 Query: 343 KKEDIAMWEVNEAFS----LVVLANIKMLEIDPQ-KVNINGGAVSLGHPIGMSGA 392 + I + + + LA ++ L ++ KV ++ S+GH +G +G+ Sbjct: 316 TPDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGS 370 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 103 PTRQAVLGAGL-----PISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P L +GL S P T C++G AI A + + G+ DVM+AGG E+ Sbjct: 157 PASLINLLSGLVSIKYGFSGPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA 214 >5BQS-A nrPDB Length = 323 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 47/135 (34%), Gaps = 10/135 (7%) Query: 63 PATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGE-GQAPTR-QAVLGAGLPISTPCT 120 + L + + + KAGI +E+ + + R QA +GA Sbjct: 49 STSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGA---NKAFAF 105 Query: 121 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNR-----GSTPYGGVKL 175 + C+ + A+ A + + G + G E++S +R GGV L Sbjct: 106 DLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLL 165 Query: 176 EDLIVKDGLTDVYNK 190 E + L + N Sbjct: 166 EASEQEHFLAESLNS 180 >4V2P-A nrPDB Length = 351 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 58 SLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAY--MGNVLQGGEGQAPTRQAVLGAGLPI 115 + A +G+ A + A+ AG+ ++ G+ Q P Q LG G Sbjct: 68 WVKGETAAFMGAEAAKEAVRDAGLQLSDIDLIISASGSPQQAVPDGGPLVQRELGLGRS- 126 Query: 116 STPCTTINKVCASGMKAIMMASQ 138 TP T+N C S A+ +AS Sbjct: 127 GTPAITVNASCLSFFVALEVASN 149 >3IL4-A nrPDB Length = 320 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 37/103 (35%), Gaps = 1/103 (0%) Query: 66 KLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKV 125 L + +EK+G E+ + V + Q G + I+ Sbjct: 53 DLCHQVAKQLLEKSGKQASEIDFILVATVTPDFNMPSVACQVQGAIGATEAF-AFDISAA 111 Query: 126 CASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGST 168 C+ + A+ MA + ++ G + G E+ S + +R + Sbjct: 112 CSGFVYALSMAEKLVLSGRYQTGLVIGGETFSKMLDWTDRSTA 154 >2IWZ-A nrPDB Length = 438 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 268 KTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEP 322 + K +G V + +GAA LVL + A + A ++ + + P Sbjct: 244 RPFHPKRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAP 296 Query: 323 IDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFS----LVVLANIKMLEIDP-QKVNIN 377 + + LKD G++ E+I+ + + IK L D + ++ Sbjct: 297 DPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVS 356 Query: 378 GGAVSLGHPIGMSGA 392 + GH +G +GA Sbjct: 357 STKGATGHLLGAAGA 371 Score = 36.9 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155 P ++ C +G A+ + + + G DVMVAGG +S Sbjct: 180 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 217 >3HO9-A nrPDB Length = 427 Score = 38.4 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTP 169 P +I SG+ I A++ + G DVMVAGG E S P + Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAST-PLGVGGFGAA 220 >3H76-A nrPDB Length = 359 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 48/137 (35%), Gaps = 5/137 (3%) Query: 33 YVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMG 92 V + + IV RT + + + L A + AIE AG+ E++ + Sbjct: 45 LVGRINTSDEFIVE--RTGVRTRYHVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVN 102 Query: 93 NVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQD-VMVAG 151 + + GL P I C+ + + MA ++ G V+V Sbjct: 103 TLSPDHHDPSQACLIQPLLGL-RHIPVLDIRAQCSGLLYGLQMARGQILAGLARHVLVVC 161 Query: 152 GMESMSNVPYVMNRGST 168 G E +S +RG Sbjct: 162 G-EVLSKRMDCSDRGRN 177 Score = 31.9 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 13/24 (54%) Query: 330 VYAASMVLKDVGLKKEDIAMWEVN 353 V AA ++ GL EDI + VN Sbjct: 79 VPAARQAIEAAGLLPEDIDLLLVN 102 >2AJ9-A nrPDB Length = 356 Score = 38.0 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 37/110 (33%), Gaps = 1/110 (0%) Query: 48 TRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQA 107 TRT I + + A + + A + A+ AG+ ++ + + Sbjct: 66 TRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMV 125 Query: 108 VLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 157 G ++ CA A+ A+ + G M+ G E +S Sbjct: 126 AASLG-AKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLS 174 Score = 31.9 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 56/168 (33%), Gaps = 30/168 (17%) Query: 280 AANASTLNDGAAALV------------LMTADAAKRLNVTPLARIVAFAD--AAVEPIDF 325 A N DGAAA+V + +D + + + FA + P Sbjct: 182 AGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVR 241 Query: 326 PIAPVY----------AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVN 375 P + G++ + I ++ ++A S + +K L++ P V Sbjct: 242 LEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVV 301 Query: 376 INGGAVSLGHPIGMSGARIVGHLTHALKQG--EYGLASICNGGGGASA 421 N + H S A I + L G + G ++ G G + Sbjct: 302 AN----DIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLS 345 >1TQY-A nrPDB Length = 424 Score = 37.3 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 61/209 (29%), Gaps = 32/209 (15%) Query: 215 AINSYTRSKAAWEAG--------KFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPK 266 ++S + A E G + P+ V +++ + Sbjct: 172 GLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHAS------ 225 Query: 267 LKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFP 326 + +G V A +GAA VL D+A A I +A Sbjct: 226 -RPFDGTRDGFVLA-------EGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTG 277 Query: 327 ---IAPVYA--ASMVLKDVGLKKEDIAMWEVNEAFSLV-----VLANIKMLEIDPQKVNI 376 A + L + DI + + + A + L ++ + Sbjct: 278 LKADGREMAETIRVALDESRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPV 337 Query: 377 NGGAVSLGHPIGMSGARIVGHLTHALKQG 405 + +GH +G G+ + AL+ G Sbjct: 338 SSIKSMVGHSLGAIGSLEIAACVLALEHG 366 Score = 33.0 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 151 P T ++ C SG+ ++ A +++ G DVM AG Sbjct: 161 PVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAG 194 >1UB7-A nrPDB Length = 322 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 43/128 (33%), Gaps = 4/128 (3%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV TRT I + + L A++ + + E V + Sbjct: 29 DEWIV--TRTGIKERRVAAEDEYTSDLAFKAVEDLLRRHPGALEGVDAVIVATNTPDALF 86 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 A++ A + + C + A+ A + G ++A G E++S + Sbjct: 87 PDTA--ALVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEALSKII 144 Query: 161 YVMNRGST 168 +R + Sbjct: 145 DWNDRATA 152 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 24/46 (52%) Query: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNIN 377 A ++ GL EDI ++ ++A ++ A + L + ++V +N Sbjct: 225 ATLEAIEKAGLTPEDIRLFVPHQANLRIIDAARERLGLPWERVAVN 270 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 37/96 (38%), Gaps = 11/96 (11%) Query: 64 ATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTIN 123 A ++ + A AIEKAG+ E+++ + A GLP ++ Sbjct: 218 AVRVMNTATLEAIEKAGLTPEDIR-----LFVPHQANLRIIDAARERLGLPWERVAVNVD 272 Query: 124 KVCASGMKAIMMA------SQSLMCGHQDVMVAGGM 153 + + +I +A + + G ++V+ G Sbjct: 273 RYGNTSTASIPLALKEAVDAGRIREGDHVLLVSFGA 308 >3GWE-A nrPDB Length = 365 Score = 36.5 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 24/167 (14%), Positives = 56/167 (33%), Gaps = 9/167 (5%) Query: 63 PATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVL--GAGLPISTPCT 120 A L A + + + ++V + Q + PT +L G+P Sbjct: 79 TAADLAYEAARKLFAQGAVGADQVDFVIL--CTQAPDYVLPTSACMLQHRLGIPTHAGAL 136 Query: 121 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPY--GGVKLEDL 178 +N C+ + + +A + G ++ ++ S + +++ G + Sbjct: 137 DVNLGCSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGASATAV 196 Query: 179 IVKDGLTDVYNKIHMGS---CAENTAKKLNIARNEQDAYAINSYTRS 222 I + G + G+ A N K + R + A + + + Sbjct: 197 IAEHGELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDA 243 >6ET0-A nrPDB Length = 365 Score = 36.1 bits (82), Expect = 0.028, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 38/106 (35%), Gaps = 14/106 (13%) Query: 307 TPLARIVAFADAAVEPIDFPIAPVY-AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIK 365 P F+D + F V A L+ GL +DI + ++ +V A + Sbjct: 239 KPRLYFSLFSDGQNKMASFVPTNVPIAMRRALEKAGLGSDDIDYFVFHQPAPFLVKAWAE 298 Query: 366 MLEIDPQKVNINGGAVSLGHPIGMSGARIVG----HLTHALKQGEY 407 + P++ + +G +G I L L++G+ Sbjct: 299 GIGARPEQYQLT---------MGDTGVMISVSIPYTLMTGLREGKI 335 >4JD3-A nrPDB Length = 353 Score = 35.7 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 32/101 (31%), Gaps = 12/101 (11%) Query: 63 PATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTI 122 A LG A+ GA++ A + ++ V R A P + Sbjct: 75 KAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPD------V 128 Query: 123 NKVCASGMKAIMMASQSLMCGHQ------DVMVAGGMESMS 157 ++ G+ ++ A+ DV V +E S Sbjct: 129 RRMPLFGLGSVAGAAGVARLRDYLRGAPDDVAVLVSVELCS 169 >4YLT-A nrPDB Length = 316 Score = 35.3 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 26/127 (20%), Positives = 46/127 (36%), Gaps = 3/127 (2%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV TRT I + +G A + A+E AGI K+++ + Sbjct: 30 DEWIV--TRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVATTSSSHAF 87 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 + Q G+ + CA A+ +A Q + G + G + +S Sbjct: 88 PSSACQVQRMLGI-KDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRAL 146 Query: 161 YVMNRGS 167 +RG+ Sbjct: 147 DPEDRGT 153 Score = 31.9 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%), Gaps = 6/63 (9%) Query: 312 IVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEV-----NEAFSLVVLANIKM 366 I A ++ + AA L+ G+ K+DI + V + AF +M Sbjct: 39 IRERRIAGLDETVATMG-FQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRM 97 Query: 367 LEI 369 L I Sbjct: 98 LGI 100 >1E5M-A nrPDB Length = 416 Score = 35.3 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 40/114 (35%), Gaps = 10/114 (8%) Query: 288 DGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKDVGL 342 +G+ L+L ++A +V +A P+ A + LKD GL Sbjct: 237 EGSGILILEELESALARGAKIYGEMVGYAMTCDAYHITAPVPDGRGATRAIAWALKDSGL 296 Query: 343 KKEDIAMWEVNEAFSLV-----VLANIKMLEIDPQKVNINGGAVSLGHPIGMSG 391 K E ++ + + A + L + ++ GH +G SG Sbjct: 297 KPEMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGGSG 350 Score = 34.6 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 29/77 (37%), Gaps = 7/77 (9%) Query: 125 VCASGMKAIMMASQSLMCGHQDVMVAGGMES----MSNVPYVMNRGSTPYGGVKLEDLIV 180 CA+G AI A + + G+ M+ GG E+ +S + R + L Sbjct: 166 ACAAGSNAIGDAFRLVQNGYAKAMICGGTEAAITPLSYAGFASARALSFRNDDPLHASRP 225 Query: 181 KDGLTDVYNKIHMGSCA 197 D D + MG + Sbjct: 226 FDKDRDGFV---MGEGS 239 >5YO9-A nrPDB Length = 371 Score = 34.9 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 35/85 (41%), Gaps = 2/85 (2%) Query: 66 KLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKV 125 + G IA + A+E AG+ E++ + + P + + L I +N Sbjct: 100 EWGVIAAKQAMENAGVTAEDIDVVILAC--SNMQRAYPAVAIEIQSALGIQGYAYDMNVA 157 Query: 126 CASGMKAIMMASQSLMCGHQDVMVA 150 ++ + A+ ++ G + V++ Sbjct: 158 ASAATFGLKQAADAIRSGARRVLLV 182 Score = 32.6 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 14/111 (12%) Query: 330 VYAASMVLKDVGLKKEDIAMW-----EVNEAFSLVVLANIKMLEID--PQKVNINGGAVS 382 V AA +++ G+ EDI + + A+ V + L I +N+ A + Sbjct: 103 VIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGIQGYAYDMNVAASAAT 162 Query: 383 LGHPIGM----SGARIVGHLTHALKQGEYGLASI-C--NGGGGASAMLIQK 426 G SGAR V + + G + C G A+A +I++ Sbjct: 163 FGLKQAADAIRSGARRVLLVNVEITSGHLDYRNRDCHFIFGDVATASIIEE 213 >5ENY-A nrPDB Length = 764 Score = 34.6 bits (78), Expect = 0.087, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 19/98 (19%) Query: 74 GAIEKAGIPKEEVKE----AYMGNVLQGGEGQAPTRQ----------AVLGAGLPI---- 115 A E AG + E Y+G ++ G RQ A+ A +P Sbjct: 273 KAFEDAGYNARTLNEKKCGVYLG-IMSNEYGVMLNRQSRANATGNSFAIAAARIPYFLNL 331 Query: 116 STPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGM 153 P I+ C+S + +A Q+L+ D+ + GG+ Sbjct: 332 KGPAIPIDTACSSSLVGTHLARQALINKEIDMALVGGV 369 >4EFI-A nrPDB Length = 354 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 46/128 (35%), Gaps = 11/128 (8%) Query: 28 YVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVK 87 +VER S +++VV + + + A L A + + G + + Sbjct: 36 FVERFDAS--AVRDVVKMIGV----NRRRWADAQTSAGDLCRKAGEKLLAGLGWQADSID 89 Query: 88 EAYMGNVLQGGEGQAPTRQAVLGAGL--PISTPCTTINKVCASGMKAIMMASQSLMCGHQ 145 V Q + P VL A L P S IN C+ +A+ + + G Sbjct: 90 ALIF--VSQTPNYRLPATAFVLQAELDLPASCLALDINLGCSGYPQALWLGMNLIQTGAA 147 Query: 146 D-VMVAGG 152 V++A G Sbjct: 148 KRVLLAVG 155 >2BZ4-A nrPDB Length = 418 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 22/48 (45%) Query: 107 AVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 A L I +I+ CA+ I A + + G QD++ AGG E Sbjct: 156 ACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGE 203 >2Z0I-A nrPDB Length = 330 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 31/111 (27%), Gaps = 8/111 (7%) Query: 236 IPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL 295 +P V Q ED V L+ F + G L+ Sbjct: 81 VPSRVPKDEQGSAADSED----SPTIEAVRLLRKTFPSLLVACDVCLCPYTSHGHCGLLS 136 Query: 296 MTADAAKRLNVTPLARI-VAFADAAVE---PIDFPIAPVYAASMVLKDVGL 342 + LA + +A+A A + P D V A L GL Sbjct: 137 ENGAFLSEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKAALLKHGL 187 >3OA3-A nrPDB Length = 288 Score = 33.8 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 50/142 (35%), Gaps = 16/142 (11%) Query: 54 SFLGSLSLLPATKLGS--IAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGA 111 + + A +L + ++ +E + + E G VL G + + Sbjct: 156 RYTDVFQDIRAVRLAAKDAILKVILETSQLTA---DEIIAGCVLSSLAGADYVKTSTGFN 212 Query: 112 GLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYG 171 G P +I V S M A+ + QS V +GG+ ++ + ++ G+ G Sbjct: 213 G-----PGASIENV--SLMSAVCDSLQS----ETRVKASGGIRTIEDCVKMVRAGAERLG 261 Query: 172 GVKLEDLIVKDGLTDVYNKIHM 193 ++ + L + M Sbjct: 262 ASAGVKIVNETRLGNRQVDEPM 283 >4OQJ-A nrPDB Length = 845 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 55/182 (30%), Gaps = 22/182 (12%) Query: 118 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGM-------------ESMSNVPYVMN 164 P + N C++ + A+ +A SL+ G + +AG E M P Sbjct: 185 PSVSTNTACSTSLVAVHLACLSLLSGDCTMALAGAAHIQADQGEGYLHHEGMIFSPDGHC 244 Query: 165 R-GSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDA--YAINSYTR 221 R G + + + L + + + G K + + D Y S Sbjct: 245 RAFDAKAQGTVIGNGVGAVVLKRLSDALADGDTVHAVIKGTAVNNDGSDKTGYTAPSVQG 304 Query: 222 SKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAA 281 A + +V P TV+ D +V L F +E + Sbjct: 305 QAAVVAEAQEIADVGPETVSYVEAHGTAT------PLGDPIEVAALNQAFNREGAALAPG 358 Query: 282 NA 283 + Sbjct: 359 SC 360 >4XOX-A nrPDB Length = 404 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 22/48 (45%) Query: 107 AVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 A L I +I+ CA+ I A + + G QD++ AGG E Sbjct: 142 ACLATPFKIRGVNYSISSACATSAHCIGNAVELIQLGKQDIVFAGGGE 189 >5BNS-A nrPDB Length = 317 Score = 32.2 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 47/127 (37%), Gaps = 3/127 (2%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV TRT I + + +G A AIE AGI K+++ + Sbjct: 30 DEWIV--TRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAF 87 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVP 160 + Q G+ P + CA A+ +A Q + G + G + ++ Sbjct: 88 PSAACQIQSMLGI-KGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTC 146 Query: 161 YVMNRGS 167 +RG+ Sbjct: 147 DPTDRGT 153 >5LBT-A nrPDB Length = 237 Score = 32.2 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 4/57 (7%) Query: 40 KEVVIVSATRTPIGSFLGSLSLLPATKL---GSIAIQGAIEKAGIPKEEVKEAYMGN 93 K+V+IV A + P SF GSL + +L G + + + G Sbjct: 4 KKVLIVYAHQEP-KSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGT 59 >6G2J-R nrPDB Length = 116 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + E++ + + +GG +LGHP Sbjct: 54 EVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHP 89 >3IL3-A nrPDB Length = 323 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 40/118 (33%), Gaps = 3/118 (2%) Query: 41 EVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEG 100 + IV TR+ I + +G A + AIE A I ++++ + Sbjct: 37 DEWIV--TRSGIRERRIAAEDETVATMGFEAAKNAIEAAQINPQDIELIIVATTSHSHAY 94 Query: 101 QAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSN 158 + Q + + + C + A+ +A Q + G + G + S Sbjct: 95 PSAACQVQGLLNIDDAI-SFDLAAACTGFVYALSVADQFIRAGKVKKALVIGSDLNSR 151 >5XTD-T nrPDB Length = 95 Score = 31.9 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 386 EVNE F++ ++A + E++ + + +GG +LGHP Sbjct: 34 EVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHP 69 >5O31-R nrPDB Length = 96 Score = 31.9 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 6/58 (10%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYG 408 EVNE F++ ++A + ++ + ++ +GG +LGHP R+ +L K G G Sbjct: 34 EVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHP------RVYINLDKETKTGTCG 85 >5VXG-A nrPDB Length = 358 Score = 31.9 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 10/94 (10%) Query: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGH-PIGMS 390 AA VL G E++ + +++ A +K IDP KV G H IG + Sbjct: 267 AAKQVL---GWAVEELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGE----HGNIGPA 319 Query: 391 GARIVGHLTHALKQGEYG--LASICNGGGGASAM 422 IV L + + G +A + G G +M Sbjct: 320 SVPIVLSKLKELGRLKKGDRIALLGIGSGLNCSM 353 >5GUP-F nrPDB Length = 123 Score = 31.9 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 6/58 (10%) Query: 351 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYG 408 EVNE F++ ++A + E+ + ++ +GG +LGHP R+ +L K G G Sbjct: 61 EVNENFAIDLIAEQPVSEVGSRVISCDGGGGALGHP------RVYINLDKETKTGTCG 112 >3OYT-A nrPDB Length = 410 Score = 31.5 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 22/48 (45%) Query: 107 AVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 A L I +I+ CA+ I A + + G QD++ AGG E Sbjct: 148 ACLATPFKIKGVNYSISSACATSAHCIGHALELIQLGKQDIVFAGGGE 195 >2P1R-A nrPDB Length = 299 Score = 31.5 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 45/132 (34%), Gaps = 28/132 (21%) Query: 230 KFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANAST-LND 288 +E I + V V + + +E +R+ TV A +N+ Sbjct: 27 LLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVE--------------TVIAGGGDGTINE 72 Query: 289 GAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKD--VGLKKED 346 + AL+ + A L + PL FA +A P A LK G E Sbjct: 73 VSTALIQIRDGVAPALGLLPLGTANDFATSAGIPE--------ALDKALKLAIAGNAME- 123 Query: 347 IAMWEVNE--AF 356 I M VN+ F Sbjct: 124 IDMAMVNDKTCF 135 >2II1-A nrPDB Length = 301 Score = 31.1 bits (69), Expect = 0.91, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 10/82 (12%) Query: 340 VGLKKEDIAMWEVNEAFSLVVLANIKML-EIDPQKVNINGGAVSLGHPIGMSGAR---IV 395 + D ++E + FS + + L ID +VN G P+ + GAR ++ Sbjct: 22 ASCQSGDTVIFETKDCFSDQITNEEQALTSIDFNRVNPATG------PLYVEGARRGDML 75 Query: 396 GHLTHALKQGEYGLASICNGGG 417 +K G+ G+ + G G Sbjct: 76 EIEILDIKVGKQGVMTAAPGLG 97 >3VEW-A nrPDB Length = 576 Score = 31.1 bits (69), Expect = 0.99, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 26/68 (38%), Gaps = 9/68 (13%) Query: 310 ARIVAFAD---AAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFS--LVVLANI 364 RI AFA+ + + APV AA+ L GL +D+ AF L + Sbjct: 30 GRIAAFAEEERLTRKKHGYNTAPVQAAAFCLAQAGLTVDDLDAV----AFGWDLPAMYRE 85 Query: 365 KMLEIDPQ 372 ++ Sbjct: 86 RLGGWPHS 93 >4KKD-A nrPDB Length = 433 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 32/100 (32%), Gaps = 22/100 (22%) Query: 90 YMGNVLQGGEGQAPT-RQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSL-------- 140 M L E + P L AG IS P T++++ +SG + + Q + Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 141 --------MCGHQDVMVAGGMESMSNVPYVMNRGSTPYGG 172 G+ V E+M Y T G Sbjct: 334 ECKTSYESRSGNYSV-----TENMFCAGYYEGGKDTCLGD 368 >4IW4-E nrPDB Length = 279 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 32/100 (32%), Gaps = 22/100 (22%) Query: 90 YMGNVLQGGEGQAPT-RQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSL-------- 140 M L E + P L AG IS P T++++ +SG + + Q + Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 141 --------MCGHQDVMVAGGMESMSNVPYVMNRGSTPYGG 172 G+ V E+M Y T G Sbjct: 180 ECKTSYESRSGNYSV-----TENMFCAGYYEGGKDTCLGD 214 >5MB9-A nrPDB Length = 590 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 71 AIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPIST----PCTTINKVC 126 ++ A++KAG+ +V E M GG P A P ST P T + + Sbjct: 342 LVESAVKKAGLDPLDVDEVIM----SGGTSNTPRIAANFRYIFPESTRILAPSTDPSALN 397 Query: 127 ASGMKAIMMASQS 139 S ++A A Q+ Sbjct: 398 PSELQARGAALQA 410 >4HA6-A nrPDB Length = 508 Score = 29.9 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 27/182 (14%), Positives = 60/182 (32%), Gaps = 18/182 (9%) Query: 52 IGSFLGS--LSLLPATKLGSIAIQGAIEKAGIPKEEV-KEAYMGNVLQ-GGEGQAPTRQA 107 +G + + G++ + ++GI +V A +G ++ G+ Sbjct: 234 VGRQGSAEVFADQIVLCAGALESPALLMRSGIGPHDVLDAAGVGCLIDMPDIGRNLQDHL 293 Query: 108 VLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGS 167 + L + +++ S A M A G +++V G+ + + + Sbjct: 294 LGAGNLYAARKPVPPSRLQHSESMAYMRADSFTAAGQPEIVVGCGVAPIVSESFPAPAAG 353 Query: 168 TPY------------GGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN--EQDA 213 + Y G V++ + D L + G E + L +R +D Sbjct: 354 SAYSLLFGITHPTSRGSVRISGPELGDRLIIDPAYLQTGRDRERFRRALEASRTIGHRDE 413 Query: 214 YA 215 A Sbjct: 414 LA 415 >4ANI-C nrPDB Length = 509 Score = 29.2 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 8/74 (10%) Query: 315 FADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIA---MWEVNEAFSLVVLANIKMLEIDP 371 F + + ++ + PV L+D GL DI + + V A + L +P Sbjct: 274 FEELSAHLVERTMGPV---RQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKRELGKEP 330 Query: 372 QK-VNINGGAVSLG 384 K VN + V++G Sbjct: 331 HKGVNPD-EVVAIG 343 >2X3E-A nrPDB Length = 331 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 50/124 (40%), Gaps = 15/124 (12%) Query: 287 NDGAAALVLMTADAAKRLNVTPLA----RIVAFADAAVEPIDFPIAPVYAASMVLKDVGL 342 +DG +LMT ++ + A R+ A + VL VG Sbjct: 184 SDGHQFDLLMTPAVSRAERSSGQASNYFRMDGKAVFGQAVTQMSD----SVRRVLDRVGW 239 Query: 343 KKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVS-LGHPIGMSGARIVGHLTHA 401 + D+ ++A + ++ A L++ ++V N ++ +G+ + S I L H Sbjct: 240 QASDLHHLVPHQANTRILAAVADQLDLPVERVVSN---IAEVGNTVAAS---IPLALAHG 293 Query: 402 LKQG 405 L+QG Sbjct: 294 LRQG 297 >4COG-A nrPDB Length = 215 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 289 GAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPI-APVYAASMVLKDVGLKKEDI 347 GAA +V A V P + +A AAVE D A +L G+K I Sbjct: 87 GAAPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGI 146 Query: 348 A 348 Sbjct: 147 D 147 >2IVO-A nrPDB Length = 330 Score = 28.8 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 11/27 (40%), Gaps = 4/27 (14%) Query: 331 YAASMVLKDVGLKKEDIAMWEVNEAFS 357 L + G+ +DI + AFS Sbjct: 53 PLLRKALSEAGVSLDDIDVI----AFS 75 >3U0E-A nrPDB Length = 428 Score = 28.4 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 41/113 (36%), Gaps = 28/113 (24%) Query: 70 IAIQGAIEKAGIPKEEVKEAYMGNVLQGG--------EGQAPTRQ--------------- 106 IA+ AI AG+ +EEV G ++ G + TR+ Sbjct: 98 IAMDQAIADAGLTEEEVSNERTGIIMGSGGPSTRTIVDSADITREKGPKRVGPFAVPKAM 157 Query: 107 -----AVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 154 A L I +I+ CA+ I A + + G QD M AGG E Sbjct: 158 SSTASATLATFFKIKGINYSISSACATSNHCIGNAYEMIQYGKQDRMFAGGCE 210 >6ET3-B nrPDB Length = 283 Score = 28.4 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 12/58 (20%) Query: 330 VYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPI 387 + A L + +K E+I + V LA L D N + A +GHP+ Sbjct: 39 LPAVREALDEAAVKPEEIDLI--------VGLA----LSPDHLIENRDIMAPKIGHPL 84 >5EP3-A nrPDB Length = 256 Score = 28.0 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 75 AIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIM 134 A+ A IPK+ ++ G+V G + RQ + ++++C + Sbjct: 57 ALNCAAIPKDLIESELFGHVKGAFTGASTERQGAVEM---AHNGTLMLDELCEMDLDLQS 113 Query: 135 MASQSLMCGHQDVMVAGGMESMSNV 159 + + G + G MS+V Sbjct: 114 KLLRFIQTGTYQKV---GSSKMSSV 135 >5OQL-Y nrPDB Length = 411 Score = 28.0 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 50/160 (31%), Gaps = 19/160 (11%) Query: 218 SYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGT 277 S RS +A G +E+ + + ++ D Y + P L GT Sbjct: 34 SKIRSSSATNPGLAPHEISFLRLLESVTNGSII--DVSYSGTTITYQPGL------ITGT 85 Query: 278 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVL 337 V NAS +D ++ T + PLA + F+ A P S Sbjct: 86 VPGMNASLSSDAIEHVIPATNTRGITYFLIPLALLAPFSKA--HLNVRFTGPGVITSATH 143 Query: 338 KDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNIN 377 L + F VL + I P ++ + Sbjct: 144 GARDLSI---------DTFRTAVLPLYGLFGIPPARIELR 174 >3ENO-A nrPDB Length = 334 Score = 28.0 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 17/51 (33%), Gaps = 11/51 (21%) Query: 311 RIVAFADAAVEPIDFPIAPVYA-----------ASMVLKDVGLKKEDIAMW 350 RI+A + P I P+ A S L+ + DI + Sbjct: 27 RILAMESSMYRPKTGGIRPLDAAVHHSEVIDTVISRALEKAKISIHDIDLI 77 >5EP0-A nrPDB Length = 396 Score = 28.0 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 75 AIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIM 134 A+ A IPK+ ++ G+V G + RQ + ++++C + Sbjct: 197 ALNCAAIPKDLIESELFGHVKGAFTGASTERQGAVEM---AHNGTLMLDELCEMDLDLQS 253 Query: 135 MASQSLMCGHQDVMVAGGMESMSNV 159 + + G + G MS+V Sbjct: 254 KLLRFIQTGTYQKV---GSSKMSSV 275 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.143 0.399 Lambda K H 0.267 0.0440 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,859,735 Number of Sequences: 36641 Number of extensions: 720855 Number of successful extensions: 2757 Number of sequences better than 10.0: 117 Number of HSP's better than 10.0 without gapping: 140 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 2245 Number of HSP's gapped (non-prelim): 295 length of query: 427 length of database: 10,336,785 effective HSP length: 100 effective length of query: 327 effective length of database: 6,672,685 effective search space: 2181967995 effective search space used: 2181967995 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.0 bits)