BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24280 (304 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AUA-A nrPDB 614 e-176 3B7N-A nrPDB 412 e-116 1O6U-A nrPDB 108 3e-24 4TLG-A nrPDB 106 1e-23 4UYB-A nrPDB 103 1e-22 3W67-A nrPDB 78 5e-15 1OIP-A nrPDB 75 5e-14 4M8Z-A nrPDB 65 4e-11 4CJ6-A nrPDB 59 2e-09 6HIX-BG nrPDB 32 0.27 3KOZ-A nrPDB 30 1.4 2BXR-A nrPDB 30 1.7 6R3V-A nrPDB 29 2.1 5WGB-A nrPDB 29 2.1 6QXS-A nrPDB 29 2.2 3TQT-A nrPDB 28 4.3 4GT2-B nrPDB 28 5.5 5T2A-AH nrPDB 28 6.9 3CC1-A nrPDB 27 9.9 >1AUA-A nrPDB Length = 296 Score = 614 bits (1584), Expect = e-176, Method: Compositional matrix adjust. Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 4 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR 63 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR Sbjct: 1 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR 60 Query: 64 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF 123 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF Sbjct: 61 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF 120 Query: 124 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS 183 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS Sbjct: 121 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS 180 Query: 184 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL 243 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL Sbjct: 181 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL 240 Query: 244 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE 299 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE Sbjct: 241 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE 296 >3B7N-A nrPDB Length = 320 Score = 412 bits (1060), Expect = e-116, Method: Compositional matrix adjust. Identities = 190/299 (63%), Positives = 238/299 (79%), Gaps = 6/299 (2%) Query: 9 FLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFD 68 L++YPQ C P+ALPGTPGNL QE+AL + R +L + + ERLDDSTLLRFLRARKFD Sbjct: 15 ILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDSTLLRFLRARKFD 74 Query: 69 VQLAKEMFENCEKWRKDYGTDTILQDFHYD------EKPLIAKFYPQYYHKTDKDGRPVY 122 + + EMF E+WR++YG +TI++D+ + E+ +AK YPQYYH DKDGRP+Y Sbjct: 75 INASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLY 134 Query: 123 FEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGI 182 FEELG +NL +M K+T+E++ML+NLV EYE YR+PACSR AG+L+ETSCT++DLKGI Sbjct: 135 FEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGI 194 Query: 183 SISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFI 242 S+S+AY V+SY+++ + ISQNYYPERMGKFYII++PFGFST F++ KPFLDPVTVSKIFI Sbjct: 195 SLSNAYHVLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFI 254 Query: 243 LGSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPEAF 301 LGSSY+KELLKQIP ENLPVK+GG S + Y SDIGPWRDP+YIGPEGE P F Sbjct: 255 LGSSYKKELLKQIPIENLPVKYGGTSVLHNPNDKFYYSDIGPWRDPRYIGPEGEIPNIF 313 >1O6U-A nrPDB Length = 403 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 132/251 (52%), Gaps = 14/251 (5%) Query: 22 LPGTPGNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENCE 80 + G G+L Q++ALA+ R+ ++D + DD LLR+LRAR FD+Q ++ M Sbjct: 1 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV 60 Query: 81 KWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSE 140 ++RK D I+ + +I ++ D DG PV+++ +G ++ + S+ Sbjct: 61 EFRKQKDIDNIIS---WQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASK 117 Query: 141 ERMLKNLVWEYESVVQYRLPACSRAA---GHLVETSCTIMDLKGISISSAY--SVMSYVR 195 + +L+ + E E ++Q C+ G VET I D +G+ + + +V +Y Sbjct: 118 QDLLRTKMRECELLLQ----ECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGE 173 Query: 196 EASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQI 255 +NY PE + + +++ AP F A+ L KPFL T KI +LG+++++ LLK I Sbjct: 174 FLCMFEENY-PETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHI 232 Query: 256 PAENLPVKFGG 266 + +PV++GG Sbjct: 233 SPDQVPVEYGG 243 >4TLG-A nrPDB Length = 404 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/246 (30%), Positives = 127/246 (51%), Gaps = 14/246 (5%) Query: 27 GNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKD 85 G+L Q++ALA R+ L+D + DD LLR+LRAR FD+Q +++M ++RK Sbjct: 7 GDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQ 66 Query: 86 YGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLK 145 D I+ + +I + D +G PVYF +G+++ + S++ M++ Sbjct: 67 QDLDNIVT---WQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIR 123 Query: 146 NLVWEYESVVQYRLPAC---SRAAGHLVETSCTIMDLKGISISSAY--SVMSYVREASYI 200 + V + L C ++ G +E + + D++G+S+ + +V Y + S + Sbjct: 124 KRI----KVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSIL 179 Query: 201 SQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENL 260 NY PE + +I AP F AF L K F+ T KI ILG ++++EL K I + L Sbjct: 180 EANY-PETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQL 238 Query: 261 PVKFGG 266 PV+FGG Sbjct: 239 PVEFGG 244 >4UYB-A nrPDB Length = 401 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 127/248 (51%), Gaps = 6/248 (2%) Query: 21 ALPGTPGNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENC 79 ++ G G+L Q + LA+ R+ ++D + DD LLR+LRAR FD+Q ++ + Sbjct: 1 SMSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKY 60 Query: 80 EKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTS 139 ++RK D IL + +I K+ P D+DG PV+++ +G ++ + + Sbjct: 61 MEFRKTMDIDHILD---WQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVT 117 Query: 140 EERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVREASY 199 ++ +LK + + E ++ + + G +ET I D +G+ + + + V + + Sbjct: 118 KQDLLKTKMRDCERIL-HECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFF 176 Query: 200 -ISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAE 258 + + YPE + I+ A F + L KPFL T KI +LG+++++ LLK I E Sbjct: 177 GLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPE 236 Query: 259 NLPVKFGG 266 LP +FGG Sbjct: 237 ELPAQFGG 244 >3W67-A nrPDB Length = 266 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 36/247 (14%) Query: 34 EKALAELRKLLEDAGFIER---LDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDT 90 + LAELR+ +++AG + L D+ LLRFLRAR FD+ LA + +N KWR + Sbjct: 13 QPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAE----- 67 Query: 91 ILQDFHYDEKPL-IAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVW 149 + D +P I YH L + S + + W Sbjct: 68 -CPELSADLRPRSILGLLKAGYHGV----------------LRSRDSTGSRVLIYRIAYW 110 Query: 150 EYESVVQYRLPACSRAAGHL----VETS----CTIMDLKGISISSAYSVM-SYVREASYI 200 + + Y + S L VET I DL+G +S A+ + S ++ + + Sbjct: 111 DPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAV 170 Query: 201 SQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENL 260 + +P ++ ++IN P F F + KPFL +I + G++Y+ +L+ P + L Sbjct: 171 LTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFP-DIL 229 Query: 261 PVKFGGK 267 P ++GGK Sbjct: 230 PREYGGK 236 >1OIP-A nrPDB Length = 278 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 23/220 (10%) Query: 53 LDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYH 112 L DS LLRFLRAR FD+ LA + +N KWR + I D H I YH Sbjct: 47 LTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAE--CPEISADLHPRS---IIGLLKAGYH 101 Query: 113 KTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVET 172 + P + L H KV + + + + E +VQ VET Sbjct: 102 GVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQE------------VET 149 Query: 173 S----CTIMDLKGISISSAYSVM-SYVREASYISQNYYPERMGKFYIINAPFGFSTAFRL 227 I DL+G S A+ + S ++ + + + +P ++ ++IN P F F + Sbjct: 150 QRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSM 209 Query: 228 FKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGK 267 KPFL +I + G++Y++ LL+ P + LP+++GG+ Sbjct: 210 IKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGE 248 >4M8Z-A nrPDB Length = 351 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 54/219 (24%), Positives = 102/219 (46%), Gaps = 19/219 (8%) Query: 53 LDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDE--KPLIA---KFY 107 L LR+LRA K+ ++ + WR+++G + ++ H D+ L+A + Sbjct: 85 LTRECFLRYLRATKWVLKDCIDRITMTLAWRREFGISHLGEE-HGDKITADLVAVENESG 143 Query: 108 PQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAG 167 Q + D RP+ + + G N + R +++LV+ E V+ + +PA + Sbjct: 144 KQVILGYENDARPILYLKPGRQN------TKTSHRQVQHLVFMLERVIDF-MPAGQDSLA 196 Query: 168 HLVETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRL 227 L++ D+ + +S + +E +I Q +YPER+GK + N P+ T +L Sbjct: 197 LLIDFK-DYPDVPKVPGNSKIPPIGVGKEVLHILQTHYPERLGKALLTNIPWLAWTFLKL 255 Query: 228 FKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGG 266 PF+DP+T K+ + + +K +P L +GG Sbjct: 256 IHPFIDPLTREKLV-----FDEPFVKYVPKNELDSLYGG 289 >4CJ6-A nrPDB Length = 317 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 34/243 (13%) Query: 31 SAQEKALAELRKLLE-DAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGT- 88 S +E A+A ++ E D+GF LRF+RARKF+V A E+ +R Y Sbjct: 76 SGEELAVAVAERVQEKDSGF--------FLRFIRARKFNVGRAYELLRGYVNFRLQYPEL 127 Query: 89 -DTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNL 147 D++ + + I YP DK GR V L + S+E + Sbjct: 128 FDSLSPE---AVRCTIEAGYPGVLSSRDKYGR--------VVMLFNIENWQSQEITFDEI 176 Query: 148 VWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSV-MSYVREASYISQNYYP 206 + Y +++ L + C I + KG ++ A S+ S +R+ + Q+ +P Sbjct: 177 LQAYCFILEKLLENEETQ----INGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFP 232 Query: 207 ERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILG---SSYQKELLKQIPAENLPVK 263 + I+ P+ F+T + + KPFL + ++F+ G S + +E+ + I LP Sbjct: 233 AWFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENI----LPSD 288 Query: 264 FGG 266 FGG Sbjct: 289 FGG 291 >6HIX-BG nrPDB Length = 378 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Query: 141 ERMLKNLVWEYESVVQYRLPACSRAAGHLVETS----CTIMDLKGIS----ISSAYSVMS 192 E +L L W+Y +V C+ ++ L+E S C +MD + ++ +Y + Sbjct: 97 ESILSQLSWDYGAVYIPLHAQCTDSSKDLLEQSCQRICAVMDALDVRWTHFLTYSYGALV 156 Query: 193 YVREASYISQNYYPERMGKFYIINAPF 219 VR AS SQ +P R+G ++ P Sbjct: 157 AVRMAS--SQE-FPHRVGTLMSLDTPL 180 >3KOZ-A nrPDB Length = 763 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 2/55 (3%) Query: 184 ISSAYSVMSYVREASYISQNYYPERMGKFYI--INAPFGFSTAFRLFKPFLDPVT 236 I A + V + ++ YYPER G IN G T F + ++ PVT Sbjct: 392 IIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVT 446 >2BXR-A nrPDB Length = 527 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 11/67 (16%) Query: 45 EDAGFIERLDDS-------TLLRFLRARKFD--VQLAKEMFEN--CEKWRKDYGTDTILQ 93 EDA LDD+ ++ F+ ARK D +L KE+ + CE + K G+ L Sbjct: 329 EDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALH 388 Query: 94 DFHYDEK 100 HY+EK Sbjct: 389 PVHYEEK 395 >6R3V-A nrPDB Length = 439 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 170 VETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFK 229 VE+ T++ L S +S++R+A Y + + YI++ T LFK Sbjct: 116 VESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFK 175 Query: 230 PFLDPVTVSKIFILGSSYQKELLKQIPAENLPV 262 P + KIF + +Y EL + + E L + Sbjct: 176 PLISFKFGQKIFYV--NYLSELSEHVKLEQLGI 206 >5WGB-A nrPDB Length = 426 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 141 ERMLKNLVWEYESVV-----QYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVR 195 ER+++N++ VV ++ P C + VE +M LK +++SS + S Sbjct: 296 ERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASL 355 Query: 196 EASYI 200 E SY+ Sbjct: 356 EPSYV 360 >6QXS-A nrPDB Length = 315 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 89 DTILQDFHYDEK--PLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKN 146 D IL D + EK L + Q+ H KDG + ++L N+ EM K + R L Sbjct: 126 DAILNDAEFAEKYGELGNIYGAQWRHWETKDGS--FIDQLA--NVIEMIKTNPDSRRLIV 181 Query: 147 LVWEYESVVQYRLPAC 162 W E V LP C Sbjct: 182 SAWNPEDVPSMALPPC 197 >3TQT-A nrPDB Length = 372 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 12/40 (30%), Positives = 25/40 (62%) Query: 182 ISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGF 221 ISI SA ++++ + A Y+ + + +G++Y+I+ P F Sbjct: 20 ISIQSAKNIVNTLDAAKYLISVIFIDHVGRWYLIDQPEMF 59 >4GT2-B nrPDB Length = 465 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 5/43 (11%) Query: 11 ESYPQNCPPDALPGTPGNLDSAQEKALA-----ELRKLLEDAG 48 +S PQ P+A GTPG LDS A R+LL AG Sbjct: 24 QSIPQTRSPEATRGTPGPLDSDNPGAATAPQGVSRRRLLGTAG 66 >5T2A-AH nrPDB Length = 144 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 20/48 (41%) Query: 84 KDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNL 131 K YG + D Y + A F + H TD GR Y + G + + Sbjct: 8 KAYGPNVKKGDLVYGVVHIFASFNDTFVHVTDMSGRETYVKVTGGMKV 55 >3CC1-A nrPDB Length = 433 Score = 26.9 bits (58), Expect = 9.9, Method: Compositional matrix adjust. Identities = 11/21 (52%), Positives = 12/21 (57%) Query: 68 DVQLAKEMFENCEKWRKDYGT 88 D L +MFE CE W K GT Sbjct: 246 DWSLLYQMFERCEVWEKHIGT 266 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AUA-A nrPDB 420 e-118 3B7N-A nrPDB 401 e-112 4UYB-A nrPDB 307 4e-84 1O6U-A nrPDB 305 2e-83 4TLG-A nrPDB 295 2e-80 3W67-A nrPDB 231 3e-61 1OIP-A nrPDB 221 3e-58 4CJ6-A nrPDB 200 6e-52 4M8Z-A nrPDB 193 1e-49 Sequences not found previously or not previously below threshold: 6R3V-A nrPDB 33 0.21 1Y79-1 nrPDB 30 1.4 2EW2-A nrPDB 29 2.0 5Z57-V nrPDB 29 2.9 2FN4-A nrPDB 29 2.9 CONVERGED! >1AUA-A nrPDB Length = 296 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 4 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR 63 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR Sbjct: 1 QQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLR 60 Query: 64 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF 123 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF Sbjct: 61 ARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYF 120 Query: 124 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS 183 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS Sbjct: 121 EELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGIS 180 Query: 184 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL 243 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL Sbjct: 181 ISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFIL 240 Query: 244 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE 299 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE Sbjct: 241 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPE 296 >3B7N-A nrPDB Length = 320 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 190/299 (63%), Positives = 238/299 (79%), Gaps = 6/299 (2%) Query: 9 FLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFD 68 L++YPQ C P+ALPGTPGNL QE+AL + R +L + + ERLDDSTLLRFLRARKFD Sbjct: 15 ILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDSTLLRFLRARKFD 74 Query: 69 VQLAKEMFENCEKWRKDYGTDTILQDFHYD------EKPLIAKFYPQYYHKTDKDGRPVY 122 + + EMF E+WR++YG +TI++D+ + E+ +AK YPQYYH DKDGRP+Y Sbjct: 75 INASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLY 134 Query: 123 FEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGI 182 FEELG +NL +M K+T+E++ML+NLV EYE YR+PACSR AG+L+ETSCT++DLKGI Sbjct: 135 FEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGI 194 Query: 183 SISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFI 242 S+S+AY V+SY+++ + ISQNYYPERMGKFYII++PFGFST F++ KPFLDPVTVSKIFI Sbjct: 195 SLSNAYHVLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFI 254 Query: 243 LGSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPEAF 301 LGSSY+KELLKQIP ENLPVK+GG S + Y SDIGPWRDP+YIGPEGE P F Sbjct: 255 LGSSYKKELLKQIPIENLPVKYGGTSVLHNPNDKFYYSDIGPWRDPRYIGPEGEIPNIF 313 >4UYB-A nrPDB Length = 401 Score = 307 bits (786), Expect = 4e-84, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 130/257 (50%), Gaps = 8/257 (3%) Query: 21 ALPGTPGNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENC 79 ++ G G+L Q + LA+ R+ ++D + DD LLR+LRAR FD+Q ++ + Sbjct: 1 SMSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKY 60 Query: 80 EKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTS 139 ++RK D IL + +I K+ P D+DG PV+++ +G ++ + + Sbjct: 61 MEFRKTMDIDHILD---WQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVT 117 Query: 140 EERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYV-REAS 198 ++ +LK + + E ++ + + G +ET I D +G+ + + + V +E Sbjct: 118 KQDLLKTKMRDCERIL-HECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFF 176 Query: 199 YISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAE 258 + + YPE + I+ A F + L KPFL T KI +LG+++++ LLK I E Sbjct: 177 GLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPE 236 Query: 259 NLPVKFGGKSEVDESKG 275 LP +FGG + + G Sbjct: 237 ELPAQFGGT--LTDPDG 251 >1O6U-A nrPDB Length = 403 Score = 305 bits (781), Expect = 2e-83, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 129/249 (51%), Gaps = 8/249 (3%) Query: 22 LPGTPGNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENCE 80 + G G+L Q++ALA+ R+ ++D + DD LLR+LRAR FD+Q ++ M Sbjct: 1 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV 60 Query: 81 KWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSE 140 ++RK D I+ + +I ++ D DG PV+++ +G ++ + S+ Sbjct: 61 EFRKQKDIDNII---SWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASK 117 Query: 141 ERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSV--MSYVREAS 198 + +L+ + E E ++Q + G VET I D +G+ + + +Y Sbjct: 118 QDLLRTKMRECELLLQ-ECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLC 176 Query: 199 YISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAE 258 +N YPE + + +++ AP F A+ L KPFL T KI +LG+++++ LLK I + Sbjct: 177 MFEEN-YPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPD 235 Query: 259 NLPVKFGGK 267 +PV++GG Sbjct: 236 QVPVEYGGT 244 >4TLG-A nrPDB Length = 404 Score = 295 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 127/249 (51%), Gaps = 6/249 (2%) Query: 21 ALPGTPGNLDSAQEKALAELRKLLEDA-GFIERLDDSTLLRFLRARKFDVQLAKEMFENC 79 ++ G+L Q++ALA R+ L+D + DD LLR+LRAR FD+Q +++M Sbjct: 1 SMSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRH 60 Query: 80 EKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTS 139 ++RK D I+ + +I + D +G PVYF +G+++ + S Sbjct: 61 MEFRKQQDLDNIVT---WQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSAS 117 Query: 140 EERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYV-REAS 198 ++ M++ + E ++ + ++ G +E + + D++G+S+ + V ++ Sbjct: 118 KQDMIRKRIKVCELLL-HECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFF 176 Query: 199 YISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAE 258 I + YPE + +I AP F AF L K F+ T KI ILG ++++EL K I + Sbjct: 177 SILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPD 236 Query: 259 NLPVKFGGK 267 LPV+FGG Sbjct: 237 QLPVEFGGT 245 >3W67-A nrPDB Length = 266 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 112/249 (44%), Gaps = 21/249 (8%) Query: 24 GTPGNLDSAQEKALAELRKLLEDAGFIERL---DDSTLLRFLRARKFDVQLAKEMFENCE 80 G+P + LAELR+ +++AG + D+ LLRFLRAR FD+ LA + +N Sbjct: 4 GSP-EFSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYY 62 Query: 81 KWRKDYGTDTILQDFHYDEKPL-IAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTS 139 KWR + + D +P I YH + L + KV + Sbjct: 63 KWRAE------CPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFT 116 Query: 140 EERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVM-SYVREAS 198 + + + E +VQ ++ I DL+G +S A+ + S ++ + Sbjct: 117 AYDVFRVSLITSELIVQ---EVETQR-----NGVKAIFDLEGWQVSHAFQITPSVAKKIA 168 Query: 199 YISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAE 258 + + +P ++ ++IN P F F + KPFL +I + G++Y+ +L+ P + Sbjct: 169 AVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFP-D 227 Query: 259 NLPVKFGGK 267 LP ++GGK Sbjct: 228 ILPREYGGK 236 >1OIP-A nrPDB Length = 278 Score = 221 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 15/220 (6%) Query: 49 FIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYP 108 L DS LLRFLRAR FD+ LA + +N KWR + I D H I Sbjct: 43 APLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAE--CPEISADLHPRS---IIGLLK 97 Query: 109 QYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGH 168 YH + P + L H KV + + + + E +VQ ++ Sbjct: 98 AGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQ---EVETQR--- 151 Query: 169 LVETSCTIMDLKGISISSAYSVM-SYVREASYISQNYYPERMGKFYIINAPFGFSTAFRL 227 I DL+G S A+ + S ++ + + + +P ++ ++IN P F F + Sbjct: 152 --NGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSM 209 Query: 228 FKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGK 267 KPFL +I + G++Y++ LL+ P + LP+++GG+ Sbjct: 210 IKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGE 248 >4CJ6-A nrPDB Length = 317 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 32/244 (13%) Query: 30 DSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGT- 88 S +E A+A ++ E D LRF+RARKF+V A E+ +R Y Sbjct: 75 ASGEELAVAVAERVQEK-------DSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPEL 127 Query: 89 -DTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNL 147 D++ + + I YP DK GR V L + S+E + Sbjct: 128 FDSLSPE---AVRCTIEAGYPGVLSSRDKYGR--------VVMLFNIENWQSQEITFDEI 176 Query: 148 VWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSV-MSYVREASYISQNYYP 206 + Y +++ L + C I + KG ++ A S+ S +R+ + Q+ +P Sbjct: 177 LQAYCFILEKLLENEETQ----INGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFP 232 Query: 207 ERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILG---SSYQKELLKQIPAENLPVK 263 + I+ P+ F+T + + KPFL + ++F+ G S + +E+ + I LP Sbjct: 233 AWFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENI----LPSD 288 Query: 264 FGGK 267 FGG Sbjct: 289 FGGT 292 >4M8Z-A nrPDB Length = 351 Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 55/242 (22%), Positives = 110/242 (45%), Gaps = 19/242 (7%) Query: 53 LDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDE--KPLIA---KFY 107 L LR+LRA K+ ++ + WR+++G + ++ H D+ L+A + Sbjct: 85 LTRECFLRYLRATKWVLKDCIDRITMTLAWRREFGISHLGEE-HGDKITADLVAVENESG 143 Query: 108 PQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAG 167 Q + D RP+ + + G N + R +++LV+ E V+ + +PA + Sbjct: 144 KQVILGYENDARPILYLKPGRQN------TKTSHRQVQHLVFMLERVIDF-MPAGQDSLA 196 Query: 168 HLVETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRL 227 L++ D+ + +S + +E +I Q +YPER+GK + N P+ T +L Sbjct: 197 LLIDF-KDYPDVPKVPGNSKIPPIGVGKEVLHILQTHYPERLGKALLTNIPWLAWTFLKL 255 Query: 228 FKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRD 287 PF+DP+T K+ + + +K +P L +GG + + + + + R+ Sbjct: 256 IHPFIDPLTREKLV-----FDEPFVKYVPKNELDSLYGGDLKFKYNHDVYWPALVETARE 310 Query: 288 PK 289 + Sbjct: 311 KR 312 >6R3V-A nrPDB Length = 439 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 189 SVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQ 248 +S++R+A Y + + YI++ T LFKP + KIF + +Y Sbjct: 135 PSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYV--NYL 192 Query: 249 KELLKQIPAENL 260 EL + + E L Sbjct: 193 SELSEHVKLEQL 204 >1Y79-1 nrPDB Length = 680 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 7/58 (12%) Query: 29 LDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDY 86 L++ Q+ ALAE+R + + + RA K D + + + + R Sbjct: 221 LNTTQQPALAEMRDR-------ATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQ 271 >2EW2-A nrPDB Length = 316 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 23/58 (39%) Query: 203 NYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENL 260 ++ E++ + F+ +P + T + G ++ L K +P EN+ Sbjct: 69 DHQNEQVDLIIALTKAQQLDAMFKAIQPMITEKTYVLCLLNGLGHEDVLEKYVPKENI 126 >5Z57-V nrPDB Length = 908 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 25/60 (41%), Gaps = 3/60 (5%) Query: 244 GSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDI-GPWRDPKYIGPEGEAPEAFS 302 GS+++ + K +++P + S V + D+ DPK GE +FS Sbjct: 774 GSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPK--KKRGERRNSFS 831 >2FN4-A nrPDB Length = 181 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 2 VTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAG 48 V+ + +SY + C D +P LD+A ++ +R+ AG Sbjct: 35 VSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAG 81 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.128 0.334 Lambda K H 0.267 0.0386 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,893,803 Number of Sequences: 36641 Number of extensions: 409295 Number of successful extensions: 1267 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 1203 Number of HSP's gapped (non-prelim): 41 length of query: 304 length of database: 10,336,785 effective HSP length: 97 effective length of query: 207 effective length of database: 6,782,608 effective search space: 1403999856 effective search space used: 1403999856 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)