BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24279 (971 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5XF8-3 nrPDB 1987 0.0 3JC7-2 nrPDB 338 6e-93 5BK4-5 nrPDB 328 8e-90 4R7Y-A nrPDB 302 6e-82 3JC6-4 nrPDB 298 8e-81 4FDG-B nrPDB 295 4e-80 3F9V-A nrPDB 295 6e-80 5U8S-7 nrPDB 268 1e-71 4R7Z-A nrPDB 196 6e-50 3F8T-A nrPDB 77 4e-14 3VX8-D nrPDB 31 2.1 6G1O-A nrPDB 31 2.2 2Q58-A nrPDB 30 4.4 1QZ1-A nrPDB 29 8.3 >5XF8-3 nrPDB Length = 997 Score = 1987 bits (5147), Expect = 0.0, Method: Compositional matrix adjust. Identities = 971/971 (100%), Positives = 971/971 (100%) Query: 1 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ 60 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ Sbjct: 27 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ 86 Query: 61 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY 120 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY Sbjct: 87 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY 146 Query: 121 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV 180 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV Sbjct: 147 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV 206 Query: 181 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK 240 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK Sbjct: 207 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK 266 Query: 241 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS 300 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS Sbjct: 267 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS 326 Query: 301 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF 360 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF Sbjct: 327 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF 386 Query: 361 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR 420 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR Sbjct: 387 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR 446 Query: 421 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD 480 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD Sbjct: 447 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD 506 Query: 481 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL 540 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL Sbjct: 507 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL 566 Query: 541 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP 600 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP Sbjct: 567 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP 626 Query: 601 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV 660 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV Sbjct: 627 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV 686 Query: 661 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT 720 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT Sbjct: 687 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT 746 Query: 721 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG 780 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG Sbjct: 747 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG 806 Query: 781 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL 840 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL Sbjct: 807 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL 866 Query: 841 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST 900 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST Sbjct: 867 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST 926 Query: 901 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN 960 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN Sbjct: 927 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN 986 Query: 961 LMVADDKVWRV 971 LMVADDKVWRV Sbjct: 987 LMVADDKVWRV 997 >3JC7-2 nrPDB Length = 868 Score = 338 bits (868), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 218/569 (38%), Positives = 316/569 (55%), Gaps = 50/569 (8%) Query: 167 SPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIP 226 S R L +L+ LV V G+VT+ + V P+L K G + D+ + RI Sbjct: 305 SLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEI--RIS 362 Query: 227 TPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKT 286 + T + + ++QR+T+QE P P G+LPR +VIL DLVD + Sbjct: 363 ----FCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVS 418 Query: 287 KPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFD 346 KPG+ V V G++K+ G +N N + F T+I N++ R G A + D Sbjct: 419 KPGEEVEVTGIYKNNYDGNLNAKNGFPV--FATIIEANSI----KRREGNTANEGEEGLD 472 Query: 347 I--------RNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSH 398 + R K+S+ + I D + S+APSIYGH IK A+ L GGV KN+ NG H Sbjct: 473 VFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNV-NGKH 531 Query: 399 -LRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRL 457 +RGDIN+L++GDP TAKSQ+L++V TA A+ TG+G+S VGLTA+V D T E L Sbjct: 532 SIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTL 591 Query: 458 EAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAAN 517 E GA+VLAD+GV IDEFDKM D DR +IHE MEQQ+++I+KAGI TTL ARCS+IAAAN Sbjct: 592 EGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAAN 651 Query: 518 PVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYL 577 P G+Y+ QN++L + +LSRFD+L VV D ++E D ++ V+ +H P Sbjct: 652 PNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHP--- 708 Query: 578 EGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAK 637 D D EE N+G +GED+ + E+ N + + K Sbjct: 709 ---------------ENDEDREGEELKNNGESAIEQGEDE---INEQLNARQRRLQRQRK 750 Query: 638 NKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDD-NTKKSP 696 + + IP+ L KY+ YA+ ++ P+L Q ++ + + Y DLR + +T P Sbjct: 751 KEEEI--SPIPQ----ELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFP 804 Query: 697 ITARTLETLIRLATAHAKVRLSKTVNKVD 725 IT R LE+++R+A + AK+RLS+ V+ D Sbjct: 805 ITVRHLESILRIAESFAKMRLSEFVSSYD 833 >5BK4-5 nrPDB Length = 775 Score = 328 bits (840), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 214/678 (31%), Positives = 348/678 (51%), Gaps = 120/678 (17%) Query: 94 HRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPW 153 + + ++++ L ++ + + EP+ IP E A+T +A + + ++ + + P Sbjct: 59 YSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPE 118 Query: 154 KLSFKG---------------SFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPK--- 195 S + A+ + R L ++H++K+V + GI+ TS++ + Sbjct: 119 NTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATY 178 Query: 196 ---LIRSVHYAAKTGRFHYRDYTDATTTL----TTRIPTPAIYPTEDTEGNKLTTE---- 244 + R+ + ++ T T +L + I + + E G++ T + Sbjct: 179 LSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGP 238 Query: 245 ------YGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVF 298 + S FID Q + +QE+PE+ P G++PR++ + D L +K PG RV +VG++ Sbjct: 239 DPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 Query: 299 KSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAAR----------QMLTDFDIR 348 + S + + + T Y + G+ + M T+ + Sbjct: 299 SIYNSKNGAGSGRSGGGNGGSGVAIRTPY---IKILGIQSDVETSSIWNSVTMFTEEEEE 355 Query: 349 NINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMV 408 +LS+ +++IL+ S+APSI+G++ IKKAI+ +LMGG +K L +G LRGDIN+L++ Sbjct: 356 EFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLL 415 Query: 409 GDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRG 468 GDP TAKSQLL+FV + +A+ T+G+GSS GLTA+V D T E LE GAMVLAD G Sbjct: 416 GDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGG 475 Query: 469 VVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRD 528 VVCIDEFDKM D DRVAIHE MEQQT++IAKAGI T LN+R SV+AAANP++G+YD + Sbjct: 476 VVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKS 535 Query: 529 PHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNL 588 P NI ++LSRFD++F+V DD NE RD SI+ HV+ Sbjct: 536 PGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINI-------------------- 575 Query: 589 SLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIP 648 H+ + ++N+ E+ NG+EI Sbjct: 576 --------------HTGNANAMQNQQEE--------------------------NGSEI- 594 Query: 649 KLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRND------DNTKKS--PITAR 700 +I +++Y+ Y + + P+L+ +A + N+ +R ++T++S PIT R Sbjct: 595 ---SIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIR 651 Query: 701 TLETLIRLATAHAKVRLS 718 LE +IR+ + AK+ LS Sbjct: 652 QLEAIIRITESLAKLELS 669 >4R7Y-A nrPDB Length = 613 Score = 302 bits (773), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 178/485 (36%), Positives = 271/485 (55%), Gaps = 37/485 (7%) Query: 96 IIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKL 155 +II D+ F+ + I+ +P E AL D +D R K+ Sbjct: 46 LIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLD--------PTYQRDIEKV 97 Query: 156 SFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHYR 212 + + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 98 HVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP 157 Query: 213 DYTDATTTLTTRIPTPAIYPTEDTEGN-KLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G +L E + ID Q+ +QE PE P+GQLP Sbjct: 158 EDEEMPEVLEM----PTICPKCGKPGQFRLIPEK--TKLIDWQKAVIQERPEEVPSGQLP 211 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 212 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 258 Query: 332 RSTGVAARQ-MLTDFDI-----RNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q +L + +I + I +L+K+KDI D + S+AP+IYG+ +KK I L L Sbjct: 259 KVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALAL 318 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV + L +G+ LRGDI++L+VGDP AKSQ+LR+V N A AI T+G+ SS GLTAA Sbjct: 319 FGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAA 378 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 D TG LEAGA+VLAD G IDE DKM+D DR IHE +EQQT++I+KAGI T Sbjct: 379 AVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITAT 438 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAAANP G+++ ++P + I LP +LLSRFDL+FV+ D+ ++ D ++ H+ Sbjct: 439 LNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHI 498 Query: 566 LRTHR 570 LR R Sbjct: 499 LRVRR 503 Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 37/91 (40%), Positives = 53/91 (58%), Gaps = 8/91 (8%) Query: 655 FLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKS--------PITARTLETLI 706 LRKY+ YA++ + P +++EA+ I K Y +R K PITAR LE LI Sbjct: 517 ILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALI 576 Query: 707 RLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 RL+ AHA++RLS V + DA+ A L+ + L Sbjct: 577 RLSEAHARMRLSPIVTREDAREAIKLMEYTL 607 >3JC6-4 nrPDB Length = 933 Score = 298 bits (763), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 201/588 (34%), Positives = 304/588 (51%), Gaps = 88/588 (14%) Query: 169 RTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTP 228 R L ++KL++++G+V +++ V P + + + D+T A I P Sbjct: 315 RELNPNDIDKLINLKGLVLRSTPVIPDM------KVAFFKCNVCDHTMAVEIDRGVIQEP 368 Query: 229 AIYPTEDT-EGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTK 287 A D E N ++ + +F D Q I +QE P+ P GQ P SI + + D+LVD + Sbjct: 369 ARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCR 428 Query: 288 PGDRVNVVGVFKSLGAGGMNQSN------------------SNTLIGFKTLILGNTVYPL 329 GDR+ V G F+S+ ++ S+ + T + + Sbjct: 429 AGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQN 488 Query: 330 HARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGV 389 V + +TD D+ I +++ ++D++ +L++S+APSIY + +KK ILL L GG Sbjct: 489 KVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGT 548 Query: 390 EKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTD 449 K G RGDINIL+ GDPST+KSQ+L++V + T+G+GSS VGLTA +T D Sbjct: 549 NKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRD 608 Query: 450 RETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNAR 509 +T + LE+GA+VL+D GV CIDEFDKM+D R +HEVMEQQT++IAKAGI TTLNAR Sbjct: 609 VDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNAR 668 Query: 510 CSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTH 569 S++A+ANP+ +Y+ N +NI LP LLSRFDL+++V D ++E DR +++H Sbjct: 669 SSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKH----- 723 Query: 570 RYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLL 629 L YLE +P + +D D+ P E + E +P++ Sbjct: 724 --LTNLYLEDKPEH--------ISQD-DVLPVEFLTMYIS----------YAKEHIHPII 762 Query: 630 QAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRND 689 AK TE+ +R YV + K D R+D Sbjct: 763 TEAAK----------TEL--------VRAYVG-----------------MRKMGDDSRSD 787 Query: 690 DNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 + K+ T R LE++IRLA AHAK++L V D + A L+R A+ Sbjct: 788 E--KRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAI 833 >4FDG-B nrPDB Length = 692 Score = 295 bits (756), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 181/484 (37%), Positives = 269/484 (55%), Gaps = 39/484 (8%) Query: 96 IIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKL 155 +II D+ F+ + I+ +P E AL D +D + V R Sbjct: 51 LIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVR----- 105 Query: 156 SFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHYR 212 G + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 106 -IVGI--PRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP 162 Query: 213 DYTDATTTLTTRIPTPAIYPTEDTEGN-KLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G +L E + ID Q+ +QE PE P+GQLP Sbjct: 163 EDEEMPEVLEM----PTICPKCGKPGQFRLIPEK--TKLIDWQKAVIQERPEEVPSGQLP 216 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 217 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 263 Query: 332 RSTGVAARQ------MLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q ++++ D + I L+K I D + S+APSIYGH +K+A+ L L Sbjct: 264 KVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 323 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV K LE+ + +RGDI+IL++GDP TAKSQ+L+F+ A A+ TTG+GS+ GLTAA Sbjct: 324 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 382 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 V ++ TGE LEAGA+VLAD G+ IDE DKM D DRVAIHE MEQQTV+IAKAGI Sbjct: 383 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 442 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAA NP FG+Y R NI LP ++LSRFDL+F++ D E +DR ++ ++ Sbjct: 443 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGE-QDRELANYI 501 Query: 566 LRTH 569 L H Sbjct: 502 LDVH 505 >3F9V-A nrPDB Length = 595 Score = 295 bits (756), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 181/484 (37%), Positives = 269/484 (55%), Gaps = 39/484 (8%) Query: 96 IIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKL 155 +II D+ F+ + I+ +P E AL D +D + V R Sbjct: 39 LIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVR----- 93 Query: 156 SFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHYR 212 G + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 94 -IVGI--PRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP 150 Query: 213 DYTDATTTLTTRIPTPAIYPTEDTEGN-KLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G +L E + ID Q+ +QE PE P+GQLP Sbjct: 151 EDEEMPEVLEM----PTICPKCGKPGQFRLIPEK--TKLIDWQKAVIQERPEEVPSGQLP 204 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 205 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 251 Query: 332 RSTGVAARQ------MLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q ++++ D + I L+K I D + S+APSIYGH +K+A+ L L Sbjct: 252 KVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 311 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV K LE+ + +RGDI+IL++GDP TAKSQ+L+F+ A A+ TTG+GS+ GLTAA Sbjct: 312 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 370 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 V ++ TGE LEAGA+VLAD G+ IDE DKM D DRVAIHE MEQQTV+IAKAGI Sbjct: 371 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 430 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAA NP FG+Y R NI LP ++LSRFDL+F++ D E +DR ++ ++ Sbjct: 431 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGE-QDRELANYI 489 Query: 566 LRTH 569 L H Sbjct: 490 LDVH 493 >5U8S-7 nrPDB Length = 845 Score = 268 bits (684), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 166/433 (38%), Positives = 254/433 (58%), Gaps = 24/433 (5%) Query: 158 KGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDA 217 K + + LS R + L +L++V GI+T+ S V+P + + + G +++ Sbjct: 217 KKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSR 276 Query: 218 TTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVI 277 T T + + +++ +L S F Q +QE+ + P G +PRS+++ Sbjct: 277 TFTPLSECTSEEC--SQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIH 334 Query: 278 LDDDLVDKTKPGDRVNVVGVF--------KSLGAGGMNQSNSNTLIGFKTLILGNTVYPL 329 ++ LV PGD V+V G+F K+L AG + ++ L Sbjct: 335 VNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTET-----------YLEAQFVRQ 383 Query: 330 HARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGV 389 H + A+ + +D + R + +L D+++ L++S+AP IYG+ +KKA+LL+L+GGV Sbjct: 384 HKKK--FASFSLTSDVEER-VMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGV 440 Query: 390 EKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTD 449 +K + +G +RGDIN+ ++GDP AKSQLL+ + + + TTG+GSSGVGLTAAV D Sbjct: 441 DKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKD 500 Query: 450 RETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNAR 509 T E LE GA+VLAD G+ CIDEFDKM + DR AIHEVMEQQT++I+KAGI+TTLNAR Sbjct: 501 PVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNAR 560 Query: 510 CSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTH 569 S++AAANP++G+Y+ P NI LP +LLSRFD+LF++ D + D ++EHV H Sbjct: 561 TSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVH 620 Query: 570 RYLPPGYLEGEPV 582 + L+ PV Sbjct: 621 MHNKQPDLDFTPV 633 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 7/87 (8%) Query: 656 LRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDD----NTKKS--PITARTLETLIRLA 709 +R+Y+ YAK + P +++ + +V+ Y LR D ++K S T RTL +IRL+ Sbjct: 638 MREYIAYAKTKR-PVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLS 696 Query: 710 TAHAKVRLSKTVNKVDAKVAANLLRFA 736 A AK+RL+ V+ D + A L+R + Sbjct: 697 QALAKLRLADMVDIDDVEEALRLVRVS 723 >4R7Z-A nrPDB Length = 338 Score = 196 bits (497), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 99/221 (44%), Positives = 137/221 (61%) Query: 350 INKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVG 409 I +L+K+KDI D + S+AP+IYG+ +KK I L L GGV + L +G+ LRGDI++L+VG Sbjct: 8 IKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVG 67 Query: 410 DPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGV 469 DP AKSQ+LR+V N A AI T+ G Sbjct: 68 DPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGY 127 Query: 470 VCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDP 529 IDE DKM+D DR IHE +EQQT++I+KAGI TLNAR +VIAAANP G+++ ++P Sbjct: 128 ALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNP 187 Query: 530 HQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHR 570 + I LP +LLSRFDL+FV+ D+ ++ D ++ H+LR R Sbjct: 188 FEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRR 228 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 37/91 (40%), Positives = 53/91 (58%), Gaps = 8/91 (8%) Query: 655 FLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKS--------PITARTLETLI 706 LRKY+ YA++ + P +++EA+ I K Y +R K PITAR LE LI Sbjct: 242 ILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALI 301 Query: 707 RLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 RL+ AHA++RLS V + DA+ A L+ + L Sbjct: 302 RLSEAHARMRLSPIVTREDAREAIKLMEYTL 332 >3F8T-A nrPDB Length = 506 Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 64/191 (33%), Positives = 96/191 (50%), Gaps = 19/191 (9%) Query: 357 KDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKS 416 KD ++++AP + G + + K + L L V KN E +++L+ G P S Sbjct: 202 KDPLTTFARAIAP-LPGAEEVGKMLALQLFSCVGKNSER-------LHVLLAGYPVVC-S 252 Query: 417 QLLRFVL-NTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEF 475 ++L VL + A + R + LTA + DR L AGA VLAD G++ +D Sbjct: 253 EILHHVLDHLAPRGVYVDLRRTELTDLTAVLKEDRGWA---LRAGAAVLADGGILAVDHL 309 Query: 476 DKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIAL 535 + + R A+ E M++ TVT+ GI LNARC+V+AA NP G+ + P I L Sbjct: 310 EGAPEPHRWALMEAMDKGTVTV--DGI--ALNARCAVLAAINP--GEQWPSDPPIARIDL 363 Query: 536 PDSLLSRFDLL 546 LS FDL+ Sbjct: 364 DQDFLSHFDLI 374 Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 45/149 (30%), Positives = 67/149 (44%), Gaps = 12/149 (8%) Query: 596 ADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPF 655 A INP E S + D + F+ + G + TE+P Sbjct: 344 AAINPGEQWPSDPPIARIDLDQD--FLSHFDLIAFLGVDPRPGEPEEQDTEVPSYT---L 398 Query: 656 LRKYVQYA-KERVIPQLTQEAINVIVKNYTDLRNDDNTKKS------PITARTLETLIRL 708 LR+Y+ YA +E P+LT+EA + Y R + + P+T R LE++ RL Sbjct: 399 LRRYLLYAIREHPAPELTEEARKRLEHWYETRREEVEERLGMGLPTLPVTRRQLESVERL 458 Query: 709 ATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 A AHA++RLS V D +AA L+ + L Sbjct: 459 AKAHARMRLSDDVEPEDVDIAAELVDWYL 487 >3VX8-D nrPDB Length = 323 Score = 31.2 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 48/103 (46%), Gaps = 8/103 (7%) Query: 47 VYNSNNAANYNDDQDDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREF 106 +YN+N ++N D++ LL + E + + ++LP ++IS DL+++ Sbjct: 91 LYNTNTVESFNK----LDKQSLLKAEANKIWEDIQSGKALEDPSVLPRFLVISFADLKKW 146 Query: 107 DRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSS 149 +W PA+ + P +L +L + + A +VS+ Sbjct: 147 SFRYWFAF---PAFVLDPP-VSLIELKPASEYFSSEEAESVSA 185 >6G1O-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 6/76 (7%) Query: 142 PNASAVSSRHP---WKLSFKGS-FGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLI 197 PNA V + P W L+F+ F A + ++A NKL+SVE T+ + V + I Sbjct: 373 PNAKLVYNNSPSFNWTLNFRQQVFDAFVAEGKDVSAYDRNKLMSVEYDDTELAKVADEKI 432 Query: 198 RSVHY--AAKTGRFHY 211 R+ +A G FH+ Sbjct: 433 RTFQRDGSAHAGIFHH 448 >2Q58-A nrPDB Length = 368 Score = 30.4 bits (67), Expect = 4.4, Method: Compositional matrix adjust. Identities = 15/63 (23%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 358 DIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQ 417 D F ++ ++ + +D I+K ++ + ++ N++ G H+RG I ++++ S+A S Sbjct: 33 DKFKVIVYNVLKKLPLNDEIRKPVIEYYLNCIDYNVKKGKHIRGKI-LVLISSLSSAYSN 91 Query: 418 LLR 420 + R Sbjct: 92 IKR 94 >1QZ1-A nrPDB Length = 291 Score = 29.3 bits (64), Expect = 8.3, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 586 LNLSLAVGEDADINPE---EHSNSGAGVENEGEDDEDHVF 622 L S+ + DAD PE + G +ENE EDDE H+F Sbjct: 210 LGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIF 249 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5XF8-3 nrPDB 1515 0.0 4R7Y-A nrPDB 627 e-180 5BK4-5 nrPDB 626 e-179 3JC7-2 nrPDB 609 e-174 3F9V-A nrPDB 604 e-173 4FDG-B nrPDB 601 e-172 3JC6-4 nrPDB 589 e-168 5U8S-7 nrPDB 502 e-142 4R7Z-A nrPDB 309 6e-84 3F8T-A nrPDB 230 2e-60 Sequences not found previously or not previously below threshold: 5EXS-A nrPDB 39 0.010 4QHS-A nrPDB 39 0.014 5EXX-A nrPDB 38 0.017 3K1J-A nrPDB 37 0.033 3DZD-A nrPDB 37 0.037 1OFI-A nrPDB 37 0.047 4ZPX-A nrPDB 37 0.052 5OFO-C nrPDB 36 0.076 1IN6-A nrPDB 36 0.087 2R44-A nrPDB 35 0.20 1Z5X-U nrPDB 34 0.37 4BS1-B nrPDB 34 0.43 1NY5-A nrPDB 34 0.43 4LZZ-A nrPDB 34 0.44 6FXY-A nrPDB 33 0.53 4YPN-A nrPDB 33 0.55 4YPL-A nrPDB 33 0.64 3M6A-A nrPDB 33 0.79 1HQC-A nrPDB 32 1.2 4L4U-A nrPDB 32 1.2 3CRV-A nrPDB 32 1.4 2IY3-A nrPDB 31 1.9 1RJ9-B nrPDB 31 1.9 4I5O-A nrPDB 31 2.1 2FFH-A nrPDB 31 2.3 3TU8-A nrPDB 31 2.4 4QMD-A nrPDB 31 2.8 1OJL-A nrPDB 31 2.9 3U5Z-B nrPDB 31 3.2 2DB3-A nrPDB 31 3.8 1QVR-A nrPDB 30 4.7 6CLZ-B nrPDB 29 8.4 3VH5-A nrPDB 29 8.7 5JHF-C nrPDB 29 8.9 2D2N-C nrPDB 29 9.4 3B0B-B nrPDB 29 9.9 CONVERGED! >5XF8-3 nrPDB Length = 997 Score = 1515 bits (3923), Expect = 0.0, Method: Composition-based stats. Identities = 971/971 (100%), Positives = 971/971 (100%) Query: 1 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ 60 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ Sbjct: 27 MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ 86 Query: 61 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY 120 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY Sbjct: 87 DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY 146 Query: 121 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV 180 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV Sbjct: 147 FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV 206 Query: 181 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK 240 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK Sbjct: 207 SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK 266 Query: 241 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS 300 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS Sbjct: 267 LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS 326 Query: 301 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF 360 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF Sbjct: 327 LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF 386 Query: 361 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR 420 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR Sbjct: 387 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR 446 Query: 421 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD 480 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD Sbjct: 447 FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD 506 Query: 481 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL 540 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL Sbjct: 507 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL 566 Query: 541 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP 600 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP Sbjct: 567 SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP 626 Query: 601 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV 660 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV Sbjct: 627 EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV 686 Query: 661 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT 720 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT Sbjct: 687 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT 746 Query: 721 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG 780 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG Sbjct: 747 VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG 806 Query: 781 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL 840 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL Sbjct: 807 SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL 866 Query: 841 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST 900 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST Sbjct: 867 GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST 926 Query: 901 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN 960 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN Sbjct: 927 GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN 986 Query: 961 LMVADDKVWRV 971 LMVADDKVWRV Sbjct: 987 LMVADDKVWRV 997 >4R7Y-A nrPDB Length = 613 Score = 627 bits (1617), Expect = e-180, Method: Composition-based stats. Identities = 192/597 (32%), Positives = 299/597 (50%), Gaps = 50/597 (8%) Query: 95 RIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWK 154 +II D+ F+ + I+ +P E AL D +D R K Sbjct: 45 SLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDP--------TYQRDIEK 96 Query: 155 LSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHY 211 + + + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 97 VHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEW 156 Query: 212 RDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G + ID Q+ +QE PE P+GQLP Sbjct: 157 PEDEEMPEVLEM----PTICPKCGKPGQ-FRLIPEKTKLIDWQKAVIQERPEEVPSGQLP 211 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 212 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 258 Query: 332 RSTGVAARQM------LTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q ++ + + I +L+K+KDI D + S+AP+IYG+ +KK I L L Sbjct: 259 KVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALAL 318 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV + L +G+ LRGDI++L+VGDP AKSQ+LR+V N A AI T+G+ SS GLTAA Sbjct: 319 FGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAA 378 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 D TG LEAGA+VLAD G IDE DKM+D DR IHE +EQQT++I+KAGI T Sbjct: 379 AVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITAT 438 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAAANP G+++ ++P + I LP +LLSRFDL+FV+ D+ ++ D ++ H+ Sbjct: 439 LNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHI 498 Query: 566 LRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKF 625 LR R P E L +A N + E ++ EK+ Sbjct: 499 LRVRRGESEVVAPKIP-HEILRKYIAYAR---------KNIHPVISEEAMEE----IEKY 544 Query: 626 NPLLQAGAKLAKNKGN-YNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVK 681 ++ K K + I +R +A+ R+ P +T+E +K Sbjct: 545 YVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIK 601 Score = 120 bits (301), Expect = 3e-27, Method: Composition-based stats. Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 31/214 (14%) Query: 547 FVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNS 606 + + D+++++ DR S H L + L+ A NP++ + Sbjct: 402 YALIDELDKMSDRDRS----VIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFN 457 Query: 607 GAGVENEGEDDEDHVFEKFNPL---------------LQAGAKLAKNKGNYNGTEIPKLV 651 E D + +F+ + + ++ + + +IP Sbjct: 458 RMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPH-- 515 Query: 652 TIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKS--------PITARTLE 703 LRKY+ YA++ + P +++EA+ I K Y +R K PITAR LE Sbjct: 516 --EILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLE 573 Query: 704 TLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 LIRL+ AHA++RLS V + DA+ A L+ + L Sbjct: 574 ALIRLSEAHARMRLSPIVTREDAREAIKLMEYTL 607 >5BK4-5 nrPDB Length = 775 Score = 626 bits (1613), Expect = e-179, Method: Composition-based stats. Identities = 225/745 (30%), Positives = 369/745 (49%), Gaps = 132/745 (17%) Query: 94 HRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPW 153 + + ++++ L ++ + + EP+ IP E A+T +A + + ++ + + P Sbjct: 59 YSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPE 118 Query: 154 KLSFKG---------------SFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPK--- 195 S + A+ + R L ++H++K+V + GI+ TS++ + Sbjct: 119 NTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATY 178 Query: 196 ---LIRSVHYAAKTGRFHYRDYTDATTTL----TTRIPTPAIYPTEDTEGNKLTTE---- 244 + R+ + ++ T T +L + I + + E G++ T + Sbjct: 179 LSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGP 238 Query: 245 ------YGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVF 298 + S FID Q + +QE+PE+ P G++PR++ + D L +K PG RV +VG++ Sbjct: 239 DPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 Query: 299 KSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAAR----------QMLTDFDIR 348 + S + + + T Y + G+ + M T+ + Sbjct: 299 SIYNSKNGAGSGRSGGGNGGSGVAIRTPY---IKILGIQSDVETSSIWNSVTMFTEEEEE 355 Query: 349 NINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMV 408 +LS+ +++IL+ S+APSI+G++ IKKAI+ +LMGG +K L +G LRGDIN+L++ Sbjct: 356 EFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLL 415 Query: 409 GDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRG 468 GDP TAKSQLL+FV + +A+ T+G+GSS GLTA+V D T E LE GAMVLAD G Sbjct: 416 GDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGG 475 Query: 469 VVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRD 528 VVCIDEFDKM D DRVAIHE MEQQT++IAKAGI T LN+R SV+AAANP++G+YD + Sbjct: 476 VVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKS 535 Query: 529 PHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNL 588 P NI ++LSRFD++F+V DD NE RD SI+ HV+ H Sbjct: 536 PGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIH------------------- 576 Query: 589 SLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIP 648 + + ++N+ E+ NG+EI Sbjct: 577 ---------------TGNANAMQNQQEE--------------------------NGSEI- 594 Query: 649 KLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRND------DNTKKS--PITAR 700 +I +++Y+ Y + + P+L+ +A + N+ +R ++T++S PIT R Sbjct: 595 ---SIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIR 651 Query: 701 TLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL-----------LGEDIGNDIDEE 749 LE +IR+ + AK+ LS + A L + + L + G + E Sbjct: 652 QLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEI 711 Query: 750 ESEYEEALSKRSPQKSPKKRQRVRQ 774 +E+ L +R P Q +R+ Sbjct: 712 R-RFEQELKRRLPIGWSTSYQTLRR 735 >3JC7-2 nrPDB Length = 868 Score = 609 bits (1570), Expect = e-174, Method: Composition-based stats. Identities = 221/648 (34%), Positives = 338/648 (52%), Gaps = 56/648 (8%) Query: 95 RIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWK 154 + ++ L E + P + + +A ++ +P+ + + S + Sbjct: 241 SLEVNYRHLAESKAILALFLAKCPEEMLKIFDL----VAMEATELHYPDYARIHS----E 292 Query: 155 LSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDY 214 + + S S R L +L+ LV V G+VT+ + V P+L K G + Sbjct: 293 IHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFF 352 Query: 215 TDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSI 274 D+ + + T + + ++QR+T+QE P P G+LPR Sbjct: 353 QDSNEEIRI------SFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHR 406 Query: 275 DVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARST 334 +VIL DLVD +KPG+ V V G++K+ G +N N + F T+I N++ R Sbjct: 407 EVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPV--FATIIEANSI----KRRE 460 Query: 335 GVAARQML--------TDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLM 386 G A + T+ + R K+S+ + I D + S+APSIYGH IK A+ L Sbjct: 461 GNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLF 520 Query: 387 GGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAV 446 GGV KN+ +RGDIN+L++GDP TAKSQ+L++V TA A+ TG+G+S VGLTA+V Sbjct: 521 GGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASV 580 Query: 447 TTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTL 506 D T E LE GA+VLAD+GV IDEFDKM D DR +IHE MEQQ+++I+KAGI TTL Sbjct: 581 RKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTL 640 Query: 507 NARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVL 566 ARCS+IAAANP G+Y+ QN++L + +LSRFD+L VV D ++E D ++ V+ Sbjct: 641 QARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVV 700 Query: 567 RTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFN 626 +H P D D EE N+G +GED+ + E+ N Sbjct: 701 DSHVRSHP------------------ENDEDREGEELKNNGESAIEQGEDE---INEQLN 739 Query: 627 PLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDL 686 + + K + + IP+ L KY+ YA+ ++ P+L Q ++ + + Y DL Sbjct: 740 ARQRRLQRQRKKEEEI--SPIPQ----ELLMKYIHYARTKIYPKLHQMDMDKVSRVYADL 793 Query: 687 RNDD-NTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLL 733 R + +T PIT R LE+++R+A + AK+RLS+ V+ D A ++ Sbjct: 794 RRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVV 841 >3F9V-A nrPDB Length = 595 Score = 604 bits (1556), Expect = e-173, Method: Composition-based stats. Identities = 178/484 (36%), Positives = 266/484 (54%), Gaps = 37/484 (7%) Query: 95 RIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWK 154 +II D+ F+ + I+ +P E AL D +D R K Sbjct: 38 SLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQ--------RDIEK 89 Query: 155 LSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHY 211 + + + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 90 VHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEW 149 Query: 212 RDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G + ID Q+ +QE PE P+GQLP Sbjct: 150 PEDEEMPEVLEM----PTICPKCGKPGQ-FRLIPEKTKLIDWQKAVIQERPEEVPSGQLP 204 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 205 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 251 Query: 332 RSTGVAARQ------MLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q ++++ D + I L+K I D + S+APSIYGH +K+A+ L L Sbjct: 252 KVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 311 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV K LE+ + +RGDI+IL++GDP TAKSQ+L+F+ A A+ TTG+GS+ GLTAA Sbjct: 312 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 370 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 V ++ TGE LEAGA+VLAD G+ IDE DKM D DRVAIHE MEQQTV+IAKAGI Sbjct: 371 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 430 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAA NP FG+Y R NI LP ++LSRFDL+F++ D E +DR ++ ++ Sbjct: 431 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGE-QDRELANYI 489 Query: 566 LRTH 569 L H Sbjct: 490 LDVH 493 Score = 86.4 bits (212), Expect = 6e-17, Method: Composition-based stats. Identities = 50/206 (24%), Positives = 91/206 (44%), Gaps = 17/206 (8%) Query: 549 VTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGA 608 V D+I+++RD + H + + L+ A NP+ Sbjct: 396 VIDEIDKMRDED----RVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISE 451 Query: 609 GVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGN--------YNGTEIPKLVTIPFLRKYV 660 ++ + + +F+ + + + ++G ++ I LRKY+ Sbjct: 452 RPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYI 511 Query: 661 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTK-KSPI--TARTLETLIRLATAHAKVRL 717 YA++ V P++T EA N+I + ++R + SPI T R LE LIR++ A+AK+ L Sbjct: 512 AYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMAL 571 Query: 718 SKTVNKVDAKVAANLLRFALLGEDIG 743 V + DA+ A N++R L E +G Sbjct: 572 KAEVTREDAERAINIMRLFL--ESVG 595 >4FDG-B nrPDB Length = 692 Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats. Identities = 178/484 (36%), Positives = 266/484 (54%), Gaps = 37/484 (7%) Query: 95 RIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWK 154 +II D+ F+ + I+ +P E AL D +D R K Sbjct: 50 SLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLD--------PTYQRDIEK 101 Query: 155 LSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVH---YAAKTGRFHY 211 + + + R + + + KL++++GI+ K + V+ ++ ++ + + F + Sbjct: 102 VHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEW 161 Query: 212 RDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLP 271 + + L P I P G + ID Q+ +QE PE P+GQLP Sbjct: 162 PEDEEMPEVLEM----PTICPKCGKPGQ-FRLIPEKTKLIDWQKAVIQERPEEVPSGQLP 216 Query: 272 RSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHA 331 R +++IL+DDLVD +PGDRV V G+ + + + V+ ++ Sbjct: 217 RQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGS-------------RAVFDIYM 263 Query: 332 RSTGVAARQ------MLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLML 385 + + + Q ++++ D + I L+K I D + S+APSIYGH +K+A+ L L Sbjct: 264 KVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 323 Query: 386 MGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAA 445 GGV K LE+ + +RGDI+IL++GDP TAKSQ+L+F+ A A+ TTG+GS+ GLTAA Sbjct: 324 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 382 Query: 446 VTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTT 505 V ++ TGE LEAGA+VLAD G+ IDE DKM D DRVAIHE MEQQTV+IAKAGI Sbjct: 383 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 442 Query: 506 LNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV 565 LNAR +VIAA NP FG+Y R NI LP ++LSRFDL+F++ D E +DR ++ ++ Sbjct: 443 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGE-QDRELANYI 501 Query: 566 LRTH 569 L H Sbjct: 502 LDVH 505 Score = 89.9 bits (221), Expect = 5e-18, Method: Composition-based stats. Identities = 53/235 (22%), Positives = 107/235 (45%), Gaps = 18/235 (7%) Query: 549 VTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGA 608 V D+I+++RD + H + + L+ A NP+ Sbjct: 408 VIDEIDKMRDED----RVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISE 463 Query: 609 GVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGN--------YNGTEIPKLVTIPFLRKYV 660 ++ + + +F+ + + + ++G ++ I LRKY+ Sbjct: 464 RPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYI 523 Query: 661 QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTK-KSPI--TARTLETLIRLATAHAKVRL 717 YA++ V P++T EA N+I + ++R + SPI T R LE LIR++ A+AK+ L Sbjct: 524 AYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMAL 583 Query: 718 SKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRV 772 V + DA+ A N++R L E +G D++ + + + ++ + P+ + +K ++ Sbjct: 584 KAEVTREDAERAINIMRLFL--ESVGVDMESGKIDIDTIMTGK-PKSAREKMMKI 635 >3JC6-4 nrPDB Length = 933 Score = 589 bits (1517), Expect = e-168, Method: Composition-based stats. Identities = 207/667 (31%), Positives = 324/667 (48%), Gaps = 97/667 (14%) Query: 95 RIIISLDDLREFD--RSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHP 152 + + +L + + +L P I ++ + D S+ + + Sbjct: 240 NLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLD----YDLDE 295 Query: 153 WKLSFKGSFGAHALS---PRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRF 209 + F + S R L ++KL++++G+V +++ V P + + + Sbjct: 296 IETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVA------FFKC 349 Query: 210 HYRDYTDATTTLTTRIPTPAIYPTEDT-EGNKLTTEYGYSTFIDHQRITVQEMPEMAPAG 268 + D+T A I PA D E N ++ + +F D Q I +QE P+ P G Sbjct: 350 NVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDG 409 Query: 269 QLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSN------------------ 310 Q P SI + + D+LVD + GDR+ V G F+S+ ++ Sbjct: 410 QTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKV 469 Query: 311 SNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPS 370 S+ + T + + V + +TD D+ I +++ ++D++ +L++S+APS Sbjct: 470 SDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPS 529 Query: 371 IYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAI 430 IY + +KK ILL L GG K G RGDINIL+ GDPST+KSQ+L++V + Sbjct: 530 IYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGV 589 Query: 431 ATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVM 490 T+G+GSS VGLTA +T D +T + LE+GA+VL+D GV CIDEFDKM+D R +HEVM Sbjct: 590 YTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVM 649 Query: 491 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVT 550 EQQT++IAKAGI TTLNAR S++A+ANP+ +Y+ N +NI LP LLSRFDL+++V Sbjct: 650 EQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVL 709 Query: 551 DDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGV 610 D ++E DR +++H L YLE +P + +D D+ P E Sbjct: 710 DKVDEKNDRELAKH-------LTNLYLEDKPEH--------ISQD-DVLPVEFLTMYIS- 752 Query: 611 ENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQ 670 + E +P++ AK +R YV Sbjct: 753 ---------YAKEHIHPIITEAAK------------------TELVRAYVG--------- 776 Query: 671 LTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAA 730 + K D R+D+ K+ T R LE++IRLA AHAK++L V D + A Sbjct: 777 --------MRKMGDDSRSDE--KRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAV 826 Query: 731 NLLRFAL 737 L+R A+ Sbjct: 827 RLIRSAI 833 >5U8S-7 nrPDB Length = 845 Score = 502 bits (1291), Expect = e-142, Method: Composition-based stats. Identities = 199/670 (29%), Positives = 319/670 (47%), Gaps = 92/670 (13%) Query: 107 DRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVS-------SRHPWKLSFKG 159 + ++ AL ++ + ++ PN + S++ + K Sbjct: 159 NEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKK 218 Query: 160 SFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATT 219 + + LS R + L +L++V GI+T+ S V+P + + + G +++ T Sbjct: 219 AISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTF 278 Query: 220 TLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILD 279 T + + +++ +L S F Q +QE+ + P G +PRS+++ ++ Sbjct: 279 TPLSECTSEE--CSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVN 336 Query: 280 DDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAAR 339 LV PGD V+V G+F + L H + A+ Sbjct: 337 GTLVRSLSPGDIVDVTGIF---LPAPYTGFKALKAGLLTETYLEAQFVRQHKKK--FASF 391 Query: 340 QMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHL 399 + +D + R + +L D+++ L++S+AP IYG+ +KKA+LL+L+GGV+K + +G + Sbjct: 392 SLTSDVEER-VMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKI 450 Query: 400 RGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEA 459 RGDIN+ ++GDP AKSQLL+ + + + TTG+GSSGVGLTAAV D T E LE Sbjct: 451 RGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEG 510 Query: 460 GAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPV 519 GA+VLAD G+ CIDEFDKM + DR AIHEVMEQQT++I+KAGI+TTLNAR S++AAANP+ Sbjct: 511 GALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPL 570 Query: 520 FGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEG 579 +G+Y+ P NI LP +LLSRFD+LF++ D + D ++EHV H + L+ Sbjct: 571 YGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDF 630 Query: 580 EPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNK 639 PV + +K + Sbjct: 631 TPV---------------------------------------------------EPSKMR 639 Query: 640 GNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITA 699 + + V + YV A +L Q++ + D T Sbjct: 640 EYIAYAKTKRPVMSEAVNDYVVQA----YIRLRQDSKREM---------DSKFSFGQATP 686 Query: 700 RTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSK 759 RTL +IRL+ A AK+RL+ V+ D + A L+R + +ES Y+E +K Sbjct: 687 RTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS------------KESLYQET-NK 733 Query: 760 RSPQKSPKKR 769 +SP + Sbjct: 734 SKEDESPTTK 743 >4R7Z-A nrPDB Length = 338 Score = 309 bits (790), Expect = 6e-84, Method: Composition-based stats. Identities = 117/340 (34%), Positives = 173/340 (50%), Gaps = 15/340 (4%) Query: 343 TDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGD 402 + + + I +L+K+KDI D + S+AP+IYG+ +KK I L L GGV + L +G+ LRGD Sbjct: 1 SPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGD 60 Query: 403 INILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAM 462 I++L+VGDP AKSQ+LR+V N A AI T+ Sbjct: 61 IHVLLVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 120 Query: 463 VLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQ 522 G IDE DKM+D DR IHE +EQQT++I+KAGI TLNAR +VIAAANP G+ Sbjct: 121 XXXXGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGR 180 Query: 523 YDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPV 582 ++ ++P + I LP +LLSRFDL+FV+ D+ ++ D ++ H+LR R P Sbjct: 181 FNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIP- 239 Query: 583 RERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGN- 641 E L +A N + E ++ EK+ ++ K K + Sbjct: 240 HEILRKYIAYAR---------KNIHPVISEEAMEE----IEKYYVRMRKSVKKTKGEEEG 286 Query: 642 YNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVK 681 I +R +A+ R+ P +T+E +K Sbjct: 287 IPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIK 326 Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats. Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 31/214 (14%) Query: 547 FVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNS 606 + + D+++++ DR S H L + L+ A NP++ + Sbjct: 127 YALIDELDKMSDRDRS----VIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFN 182 Query: 607 GAGVENEGEDDEDHVFEKFNPL---------------LQAGAKLAKNKGNYNGTEIPKLV 651 E D + +F+ + + ++ + + +IP Sbjct: 183 RMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPH-- 240 Query: 652 TIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKS--------PITARTLE 703 LRKY+ YA++ + P +++EA+ I K Y +R K PITAR LE Sbjct: 241 --EILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLE 298 Query: 704 TLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 LIRL+ AHA++RLS V + DA+ A L+ + L Sbjct: 299 ALIRLSEAHARMRLSPIVTREDAREAIKLMEYTL 332 >3F8T-A nrPDB Length = 506 Score = 230 bits (586), Expect = 2e-60, Method: Composition-based stats. Identities = 83/359 (23%), Positives = 138/359 (38%), Gaps = 53/359 (14%) Query: 288 PGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDI 347 PG RV ++G+ +S + + + ++ Sbjct: 157 PGLRVEILGIVRSATLDALEVHKKDPIPEVHPDPA-----------------------EL 193 Query: 348 RNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILM 407 +L+ KD ++++AP + G + + K + L L V KN E +++L+ Sbjct: 194 EEFRELA-DKDPLTTFARAIAP-LPGAEEVGKMLALQLFSCVGKNSER-------LHVLL 244 Query: 408 VGDPSTAKSQLLRFVL-NTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLAD 466 G P S++L VL + A + R + LTA + DR L AGA VLAD Sbjct: 245 AGYPVVC-SEILHHVLDHLAPRGVYVDLRRTELTDLTAVLKEDRGWA---LRAGAAVLAD 300 Query: 467 RGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVN 526 G++ +D + + R A+ E M++ TVT+ GI LNARC+V+AA NP G+ + Sbjct: 301 GGILAVDHLEGAPEPHRWALMEAMDKGTVTV--DGI--ALNARCAVLAAINP--GEQWPS 354 Query: 527 RDPHQNIALPDSLLSRFDLLFVVTDDIN----EIRDRS------ISEHVLRTHRYLPPGY 576 P I L LS FDL+ + D E +D + ++L R P Sbjct: 355 DPPIARIDLDQDFLSHFDLIAFLGVDPRPGEPEEQDTEVPSYTLLRRYLLYAIREHPAPE 414 Query: 577 LEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKL 635 L E + + E+ + + + E E L + Sbjct: 415 LTEEARKRLEHWYETRREEVEERLGMGLPTLPVTRRQLESVERLAKAHARMRLSDDVEP 473 Score = 149 bits (376), Expect = 5e-36, Method: Composition-based stats. Identities = 45/149 (30%), Positives = 67/149 (44%), Gaps = 12/149 (8%) Query: 596 ADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPF 655 A INP E S + D + F+ + G + TE+P Sbjct: 344 AAINPGEQWPSDPPIARIDLDQD--FLSHFDLIAFLGVDPRPGEPEEQDTEVPSYT---L 398 Query: 656 LRKYVQYA-KERVIPQLTQEAINVIVKNYTDLRNDDNTKKS------PITARTLETLIRL 708 LR+Y+ YA +E P+LT+EA + Y R + + P+T R LE++ RL Sbjct: 399 LRRYLLYAIREHPAPELTEEARKRLEHWYETRREEVEERLGMGLPTLPVTRRQLESVERL 458 Query: 709 ATAHAKVRLSKTVNKVDAKVAANLLRFAL 737 A AHA++RLS V D +AA L+ + L Sbjct: 459 AKAHARMRLSDDVEPEDVDIAAELVDWYL 487 >5EXS-A nrPDB Length = 260 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 17/125 (13%) Query: 402 DINILMVGDPSTAKSQLLRFVLNTASL-----------AIATTGRGSSGVGLTAAVTTDR 450 D ++L++G+ T K + R + + AI S G Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 451 ETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARC 510 TG AG LA+ G + +DE M +V + V++++T + G + T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 511 SVIAA 515 +IAA Sbjct: 147 RIIAA 151 >4QHS-A nrPDB Length = 267 Score = 38.6 bits (88), Expect = 0.014, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 74/203 (36%), Gaps = 26/203 (12%) Query: 376 HIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASL--AIATT 433 K LL L V K D N++++G + K + R++ N + Sbjct: 21 DTKSLKLLALADKVAKT---------DANVMILGPSGSGKEVMSRYIHNASPRKEGPFIA 71 Query: 434 GRGSSGVG--LTAAV---TTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHE 488 ++ L A + TG + G A G + +DE +M + + Sbjct: 72 INCAAIPDNMLEATLFGYEKGAFTGAVQACPGKFEQAQGGTILLDEISEMDLNLQAKLLR 131 Query: 489 VMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFV 548 V++++ V + L+ R V+A +N QY Q + L R ++ + Sbjct: 132 VLQEREVERLGSRKSIKLDVR--VLATSNRDLKQY------VQAGHFREDLYYRLNVFPL 183 Query: 549 VTDDINEIRD--RSISEHVLRTH 569 + E +D ++ H++ H Sbjct: 184 TWPALCERKDDIEPLANHLIERH 206 >5EXX-A nrPDB Length = 343 Score = 38.3 bits (87), Expect = 0.017, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 17/125 (13%) Query: 402 DINILMVGDPSTAKSQLLRFVLNTASL-----------AIATTGRGSSGVGLTAAVTTDR 450 D ++L++G+ T K + R + + AI S G Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 451 ETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARC 510 TG AG LA+ G + +DE M +V + V++++T + G + T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 511 SVIAA 515 +IAA Sbjct: 147 RIIAA 151 >3K1J-A nrPDB Length = 604 Score = 37.5 bits (85), Expect = 0.033, Method: Composition-based stats. Identities = 66/360 (18%), Positives = 126/360 (35%), Gaps = 36/360 (10%) Query: 404 NILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMV 463 ++L++G+P T KS L + + + + + V Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLPTETLED------------ILVFPNPEDENMPRIKTV 109 Query: 464 LADRGVVCIDEF-DKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQ 522 A +G ++++ +K + V + + TV + K + + I A G Sbjct: 110 PACQGRRIVEKYREKAKSQESVKSSNMRLKSTVLVPKLLVDNCGRTKAPFIDATGAHAGA 169 Query: 523 Y--DVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGE 580 DV DP Q+ L R + + + I+ L+ + L E + Sbjct: 170 LLGDVRHDPFQSGGLGTPAHERVEPGMIHRAHKGVLFIDEIATLSLKMQQSLLTAMQEKK 229 Query: 581 -PVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNK 639 P+ + +S + P + AG +K +P L++ + Sbjct: 230 FPITGQSEMSSGAMVRTEPVPCDFVLVAAG--------NLDTVDKMHPALRSRIR-GYGY 280 Query: 640 GNYNGTEIPKLVTIPFLRKYVQYA-----KERVIPQLTQEAINVIVKNYTDLRNDDNTKK 694 Y T +P TI RK VQ+ ++ IP T+EA+ IV+ + Sbjct: 281 EVYMRTTMPD--TIENRRKLVQFVAQEVKRDGKIPHFTKEAVEEIVR--EAQKRAGRKGH 336 Query: 695 SPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYE 754 + R L ++R A A + K V + D A + + L + + + E + EY+ Sbjct: 337 LTLRLRDLGGIVRAAGDIAVKKGKKYVEREDVIEAVKMAKP--LEKQLADWYIERKKEYQ 394 >3DZD-A nrPDB Length = 368 Score = 37.1 bits (84), Expect = 0.037, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 46/119 (38%), Gaps = 8/119 (6%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASL-AIATTGRGSSGVGLTAAVT-----TDRETGERRLE 458 +L+ G+ T K + R + + +S A TG + Sbjct: 155 VLITGESGTGKEIVARLIHRYSGRKGAFVDLNCASIPQELAESELFGHEKGAFTGALTRK 214 Query: 459 AGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAAN 517 G + LAD+G + +DE ++ + + V+E T + + G + + VI+A N Sbjct: 215 KGKLELADQGTLFLDEVGELDQRVQAKLLRVLE--TGSFTRLGGNQKIEVDIRVISATN 271 >1OFI-A nrPDB Length = 310 Score = 36.7 bits (83), Expect = 0.047, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 46/126 (36%), Gaps = 16/126 (12%) Query: 363 LSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDI-------NILMVGDPSTAK 415 + L I G K+A+ + L +N L+ + NILM+G K Sbjct: 9 IVSELDQHIIGQADAKRAVAIAL-----RNRWRRMQLQEPLRHEVTPKNILMIGPTGVGK 63 Query: 416 SQLLRFVLNTASLAIATTGRGSSGVGLTAAVTT-DRETGERRLEAGAMVLA--DRGVVCI 472 +++ R + A A + + D + AG + A G+V I Sbjct: 64 TEIARRLAKLA-NAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFI 122 Query: 473 DEFDKM 478 DE DK+ Sbjct: 123 DEIDKI 128 >4ZPX-A nrPDB Length = 413 Score = 36.7 bits (83), Expect = 0.052, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 623 EKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYA-----KERVIPQLTQEAIN 677 +K +P L++ + Y T +P TI RK VQ+ ++ IP T+EA+ Sbjct: 302 DKMHPALRSRIR-GYGYEVYMRTTMPD--TIENRRKLVQFVAQEVKRDGKIPHFTKEAVE 358 Query: 678 VIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLR 734 IV+ + + R L ++R A A + K V + D A + + Sbjct: 359 EIVR--EAQKRAGRKGHLTLRLRDLGGIVRAAGDIAVKKGKKYVEREDVIEAVKMAK 413 Score = 30.2 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 14/24 (58%) Query: 404 NILMVGDPSTAKSQLLRFVLNTAS 427 ++L++G+P T KS L + + Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >5OFO-C nrPDB Length = 871 Score = 35.9 bits (81), Expect = 0.076, Method: Composition-based stats. Identities = 66/402 (16%), Positives = 125/402 (31%), Gaps = 84/402 (20%) Query: 387 GGVEKNLENGSHLRGDINIL---------MVGDPSTAKSQLLRFVLNTASLAIATTGRGS 437 G ++ + +R I +L ++G+P K+ + V A I G Sbjct: 179 GKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAI---VEGLAQRII----NGE 231 Query: 438 SGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHE-VMEQQTVT 496 GL + L+ GA+V G EF+ + + +++ ++ V Sbjct: 232 VPEGL-------KGRRVLALDMGALV---AGAKYRGEFE---ERLKGVLNDLAKQEGNVI 278 Query: 497 IAKAGIHTTLNARCS--VIAAAN---PVFGQ-------YDVNRDPHQNIALPDSLLSRFD 544 + +HT + A + + A N P + + Q I +L RF Sbjct: 279 LFIDALHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ 338 Query: 545 LLFVVTDDINE--------IRDRSISEHV-----------LRTHRYLPPGYLEGEPVRER 585 +FV + + + HV +HRY+ L + + Sbjct: 339 KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLI 398 Query: 586 LNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEK----------FNPLLQAGAKL 635 + ++ D PEE + + + + E N L + Sbjct: 399 DEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQ 458 Query: 636 AKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLR-NDDNTKK 694 E L ++ ++ AK AI + R ++ K Sbjct: 459 YSELEEEWKAEKASLSGTQTIKAELEQAKI---------AIEQARRVGDLARMSELQYGK 509 Query: 695 SPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFA 736 P + LE +L ++ L V DA++A L R+ Sbjct: 510 IPELEKQLEAATQLEGKTMRL-LRNKVT--DAEIAEVLARWT 548 >1IN6-A nrPDB Length = 334 Score = 35.9 bits (81), Expect = 0.087, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 59/152 (38%), Gaps = 30/152 (19%) Query: 353 LSKKKDIFDILSQSLAP----SIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDI--NIL 406 L+ ++ ++D Q L P G +++KK + L L + +RG++ ++L Sbjct: 5 LTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLAL---------EAAKMRGEVLDHVL 55 Query: 407 MVGDPSTAKSQLLRFVLNTASLAIA-TTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLA 465 + G P ++ L + + I T+G G AA+ T L Sbjct: 56 LAGPPGLGRTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTS--------------LE 101 Query: 466 DRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTI 497 V+ IDE ++ ++ +E + I Sbjct: 102 RGDVLFIDEIHRLNKAVEELLYSAIEDFQIDI 133 >2R44-A nrPDB Length = 331 Score = 34.8 bits (78), Expect = 0.20, Method: Composition-based stats. Identities = 49/311 (15%), Positives = 102/311 (32%), Gaps = 41/311 (13%) Query: 404 NILMVGDPSTAKSQLLRFVLNTA----SLAIATTGRGSSGVGLTAAVTTDRETGERRLEA 459 +IL+ G P AK+ + + T T S L + ++ G ++ Sbjct: 48 HILLEGVPGLAKTLSVNTLAKTMDLDFHRIQFTPDLLPS--DLIGTMIYNQHKGNFEVKK 105 Query: 460 GAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPV 519 G + + DE ++ + A+ E M+++ VTI L+ V+A NPV Sbjct: 106 GPVF---SNFILADEVNRSPAKVQSALLECMQEKQVTIGDT--TYPLDNPFLVLATQNPV 160 Query: 520 FGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEG 579 + + LP++ + RF ++ + +++ + + V Sbjct: 161 --EQEGTYP------LPEAQVDRF-MMKIHLTYLDKESELEVMRRVSN------------ 199 Query: 580 EPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNK 639 +N + V + N + E E ++ E + + Sbjct: 200 ------MNFNYQVQKIVSKNDVLEIRNEINKVTISESLEKYIIELVFATRFPAEYGLEAE 253 Query: 640 GNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLR---NDDNTKKSP 696 +Y I R A + E I + + + R N + + Sbjct: 254 ASYILYGASTRAAINLNRVAKAMAFFNNRDYVLPEDIKEVAYDILNHRIILNYEAEAEGI 313 Query: 697 ITARTLETLIR 707 T + +ET++R Sbjct: 314 STRQIIETILR 324 >1Z5X-U nrPDB Length = 262 Score = 33.6 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 45/124 (36%), Gaps = 10/124 (8%) Query: 55 NYNDDQDDADERDLLGDDDGDDLEKEKKAASST--SLNILPHRIIISLD-DLREFDRSFW 111 +Y DD D +R+ + ++ + EK + ST S N +P I+ + + + Sbjct: 2 DYKDDDDKGPKREAVQEERQRNKEKSENEVESTSNSQNDMPIERILEAELRVEPKNEDID 61 Query: 112 SGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSS-----RHPWKLSFKGSFGAHAL 166 S + A++ L L + +PH V + W F ++ Sbjct: 62 SR--DPVSDICQAADRQLYQLIEWAKHIPHFTELPVEDQVILLKSGWNELLIAGFSHRSM 119 Query: 167 SPRT 170 S + Sbjct: 120 SVKD 123 >4BS1-B nrPDB Length = 173 Score = 33.6 bits (75), Expect = 0.43, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 44/125 (35%), Gaps = 19/125 (15%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERR-LEAGAMV 463 +L+ G+ K + R + + + + A++ D E E GA Sbjct: 27 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 81 Query: 464 -----------LADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSV 512 LAD G + +DE +++ + + V+E + G + + Sbjct: 82 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 139 Query: 513 IAAAN 517 +AA N Sbjct: 140 LAATN 144 >1NY5-A nrPDB Length = 387 Score = 33.6 bits (75), Expect = 0.43, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 44/125 (35%), Gaps = 19/125 (15%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERR-LEAGAMV 463 +L+ G+ K + R + + + + A++ D E E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 217 Query: 464 -----------LADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSV 512 LAD G + +DE +++ + + V+E + G + + Sbjct: 218 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 275 Query: 513 IAAAN 517 +AA N Sbjct: 276 LAATN 280 >4LZZ-A nrPDB Length = 268 Score = 33.6 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 44/125 (35%), Gaps = 19/125 (15%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERR-LEAGAMV 463 +L+ G+ K + R + + + + A++ D E E GA Sbjct: 44 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 98 Query: 464 -----------LADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSV 512 LAD G + +DE +++ + + V+E + G + + Sbjct: 99 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 156 Query: 513 IAAAN 517 +AA N Sbjct: 157 LAATN 161 >6FXY-A nrPDB Length = 718 Score = 33.3 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 19/138 (13%), Positives = 41/138 (29%), Gaps = 5/138 (3%) Query: 520 FGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEG 579 GQ + P L RF ++ D + ++ + + P + Sbjct: 268 GGQPPPRVFLAVFVEQPTPFLPRFLQRLLLLDYPPD----RVTLFLHNNEVFHEPHIADS 323 Query: 580 EPV-RERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKN 638 P ++ + VG + ++P E + + + + E + + +L L Sbjct: 324 WPQLQDHFSAVKLVGPEEALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRIL 383 Query: 639 KGNYNGTEIPKLVTIPFL 656 P L L Sbjct: 384 IEENRKVIAPMLSRHGKL 401 >4YPN-A nrPDB Length = 293 Score = 33.3 bits (74), Expect = 0.55, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 15/130 (11%) Query: 372 YGHDHIKKAILLMLMGGVEKNLENGSHLRGDINIL-MVGDPSTAKSQLLRFVLNTASLAI 430 YG +K+ IL L + L G +R IL +VG P K+ L R + + + Sbjct: 115 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 171 Query: 431 ATTGRGSSGVGLTAAVTTDRET-----GERRLEAGAMVLADRGVVCIDEFDKMTDVDR-- 483 G GV A + R T + + A V V+ +DE DKM+ R Sbjct: 172 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGD 229 Query: 484 --VAIHEVME 491 A+ EV++ Sbjct: 230 PASAMLEVLD 239 >4YPL-A nrPDB Length = 555 Score = 32.9 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 61/298 (20%), Positives = 102/298 (34%), Gaps = 45/298 (15%) Query: 372 YGHDHIKKAILLMLMGGVEKNLENGSHLRGDINIL-MVGDPSTAKSQLLRFVLNTASLAI 430 YG +K+ IL L + L G +R IL +VG P K+ L R + + + Sbjct: 82 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 138 Query: 431 ATTGRGSSGVGLTAAVTTDRET-----GERRLEAGAMVLADRGVVCIDEFDKMTDVDR-- 483 G GV A + R T + + A V V+ +D+ DKM+ R Sbjct: 139 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDQIDKMSSDWRGD 196 Query: 484 --VAIHEVME-QQTVTIAKAGIHTTLN-ARCSVIAAANPVFGQYDVNRDPHQNIALPDSL 539 A+ EV++ +Q T + + ++ I AN + +P L Sbjct: 197 PASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQ-------------TIPRPL 243 Query: 540 LSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADIN 599 L R +++ I + + + YL + VRE DA I Sbjct: 244 LDRMEVI-------------EIPGYTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAIL 290 Query: 600 PEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLR 657 + E + + K GA + + ++IP + IP R Sbjct: 291 RVISEYTREAGVRGLERELGKIARKGAKFWLEGA--WEGLRTIDASDIPTYLGIPRYR 346 >3M6A-A nrPDB Length = 543 Score = 32.9 bits (73), Expect = 0.79, Method: Composition-based stats. Identities = 44/180 (24%), Positives = 72/180 (40%), Gaps = 29/180 (16%) Query: 372 YGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIA 431 +G + +K+ IL L V+K L+G I + + G P K+ L + + Sbjct: 84 HGLEKVKERILEYL--AVQKLT---KSLKGPI-LCLAGPPGVGKTSLAKSIAK------- 130 Query: 432 TTGRGSSGVGLTAAVTTDRETGERRLEAGAMV------LADRG----VVCIDEFDKMTDV 481 + GR + L G RR GAM + G V +DE DKM+ Sbjct: 131 SLGRKFVRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGKLNPVFLLDEIDKMSSD 190 Query: 482 DR----VAIHEVME-QQTVTIAKAGIHTTLN-ARCSVIAAANPVFGQYDVNRDPHQNIAL 535 R A+ EV++ +Q + + I T + ++ IA AN + RD + I + Sbjct: 191 FRGDPSSAMLEVLDPEQNSSFSDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIINI 250 >1HQC-A nrPDB Length = 324 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 50/144 (34%), Gaps = 22/144 (15%) Query: 404 NILMVGDPSTAKSQLLRFVLN-TASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAM 462 ++L+ G P K+ L + + T+G G AA+ A Sbjct: 40 HLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAIL-------------AN 86 Query: 463 VLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQ 522 L + ++ IDE +++ ++ ME + I I AR + P F Sbjct: 87 SLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIV---IGQGPAARTIRLEL--PRFTL 141 Query: 523 YDVNRDPHQNIALPDSLLSRFDLL 546 P + LLSRF ++ Sbjct: 142 IGATTRPGL---ITAPLLSRFGIV 162 >4L4U-A nrPDB Length = 447 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 19/125 (15%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERR-LEAGAMV 463 +L+ G+ K + R + ++ + + A++ D E E GA Sbjct: 171 VLITGESGVGKEVVARLIHKSSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 225 Query: 464 -----------LADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSV 512 LAD G + +DE +++ + + V+E + G + + Sbjct: 226 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 283 Query: 513 IAAAN 517 +AA N Sbjct: 284 LAATN 288 >3CRV-A nrPDB Length = 551 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 46/112 (41%), Gaps = 1/112 (0%) Query: 597 DINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFL 656 DI+ E+ N + +E +Q K +K++ + + Sbjct: 169 DIDLREYMIVIDEAHNLDKVNELEERSLSEITIQMAIKQSKSEESRRILSKLLNQLREVV 228 Query: 657 RKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRL 708 +Y K +P+L++E + ++ +Y D+R D + K+ + + +++R Sbjct: 229 LPDEKYIKVENVPKLSKEELEILADDYEDIRKD-SLKQGKVNKIHIGSILRF 279 >2IY3-A nrPDB Length = 432 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 707 RLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDI--DEEESEYEEALSKR 760 RL A ++R + + D K +R AL+ D+ ++ D E EEAL K+ Sbjct: 8 RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARDFVERVREEALGKQ 63 >1RJ9-B nrPDB Length = 300 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 707 RLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEE--ESEYEEALSKR 760 RL A ++R + + D K +R AL+ D+ ++ + E EEAL K+ Sbjct: 8 RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTRDFVERVREEALGKQ 63 >4I5O-A nrPDB Length = 363 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 25/173 (14%) Query: 371 IYGHDHIKKAILLMLMGGVEK----NLENGSHLRGDINILMVGDPSTAKSQLLRFVLNT- 425 + G + KK + + + ++ + NG L G NIL++G + K+ L + Sbjct: 17 VIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVEL-GKSNILLIGPTGSGKTLLAETLARLL 75 Query: 426 -----ASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMT- 479 + A T G G + + + + ++ A RG+V IDE DK++ Sbjct: 76 DVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQK-----AQRGIVYIDEIDKISR 130 Query: 480 DVDRVAIHEVMEQQTVTIAKAGI-HTTLNARCSVIAAANPVFGQYDVNRDPHQ 531 D +I T ++ G+ L +AA P G+ ++ Q Sbjct: 131 KSDNPSI-------TRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQ 176 >2FFH-A nrPDB Length = 425 Score = 31.3 bits (69), Expect = 2.3, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 707 RLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEE--ESEYEEALSKR 760 RL A ++R + + D K +R AL+ D+ ++ + E EEAL K+ Sbjct: 8 RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTRDFVERVREEALGKQ 63 >3TU8-A nrPDB Length = 210 Score = 31.3 bits (69), Expect = 2.4, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 42/110 (38%), Gaps = 4/110 (3%) Query: 283 VDKTKPGDRVNVVGVFKSLGAGGMN--QSNSNTLIGFKTLILGNTVYPLHARSTGVAARQ 340 + +PG V +F + G + + + N + + + + Sbjct: 70 LQTLQPGSISTVDMLFFTYYLSGCKVFAGDGGPVWHIDAPVEANQFWRRMSSDEWMEDWE 129 Query: 341 MLTDFDIRNINKLSKKKDI--FDILSQSLAPSIYGHDHIKKAILLMLMGG 388 + TD + +++ + + + APS YG D++ +A++ ++ G Sbjct: 130 VGTDRQVAYLHRAGQSDSLWNLSAYLEGAAPSTYGRDNLGQAVVGGIVTG 179 >4QMD-A nrPDB Length = 193 Score = 30.9 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 13/93 (13%) Query: 429 AIATTGRGSSGVGLTAAVTT--DRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAI 486 I T + TA D TG++ LEA A A G+V + +R ++ Sbjct: 8 GIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQA---ATGGIV------DLLSRERYSV 58 Query: 487 HEVMEQQTVTIAKAGIHTTLNARCSVIAAANPV 519 H+ ME+ I LNA+ + +PV Sbjct: 59 HKAMERGL--IENTSTQRLLNAQKAFTGIEDPV 89 >1OJL-A nrPDB Length = 304 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 34/184 (18%), Positives = 72/184 (39%), Gaps = 35/184 (19%) Query: 402 DINILMVGDPSTAKSQLLRFVLNTASL-----------AIATTGRGSSGVGLTAAVTTDR 450 D +L+ GD T K + R + ++ A+ + S G Sbjct: 25 DATVLIHGDSGTGKELVARALHACSARSDRPLVTLNCAALNESLLESELFGH----EKGA 80 Query: 451 ETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARC 510 TG + G V AD G + +DE ++ + +V + ++++ + + G + T++ Sbjct: 81 FTGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQER--EVQRVGSNQTISVDV 138 Query: 511 SVIAAANPVFGQYDVNRDPHQNIA---LPDSLLSRFDLLFVVTDDINEIRDRS----ISE 563 +IAA + RD + ++ L R ++ V + + + R +++ Sbjct: 139 RLIAATH---------RDLAEEVSAGRFRQDLYYRLNV--VAIEMPSLRQRREDIPLLAD 187 Query: 564 HVLR 567 H LR Sbjct: 188 HFLR 191 >3U5Z-B nrPDB Length = 324 Score = 30.6 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 39/122 (31%), Gaps = 15/122 (12%) Query: 405 ILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVL 464 IL P T K+ + + + + + +G T + A Sbjct: 51 ILHSPSPGTGKTTVAKALCH----DVNADMMFVNGSDCKIDFVRGPLTN---FASAASFD 103 Query: 465 ADRGVVCIDEFDKM----TDVDRVAIHEVMEQQTVTIAKA----GIHTTLNARCSVIAAA 516 + V+ IDEFD+ + + E I A GI L +RC VI Sbjct: 104 GRQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQSRCRVITFG 163 Query: 517 NP 518 P Sbjct: 164 QP 165 >2DB3-A nrPDB Length = 434 Score = 30.6 bits (67), Expect = 3.8, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 27/73 (36%), Gaps = 5/73 (6%) Query: 535 LPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGE 594 + + ++ D FVV D+ + + D SE + R ++ P + L S E Sbjct: 194 VDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVT-----MRPEHQTLMFSATFPE 248 Query: 595 DADINPEEHSNSG 607 + E + Sbjct: 249 EIQRMAGEFLKNY 261 >1QVR-A nrPDB Length = 854 Score = 30.2 bits (66), Expect = 4.7, Method: Composition-based stats. Identities = 74/431 (17%), Positives = 147/431 (34%), Gaps = 68/431 (15%) Query: 339 RQMLTDFDIRNINKLSKKKDIFDILSQS--LAPSIYGHDHIKKAILLMLMGGVEKNLENG 396 R + T+ N L + L+ L P I + I++ I ++L Sbjct: 139 RTVQTEHAESTYNALEQYGIDLTRLAAEGKLDPVIGRDEEIRRVIQILL----------- 187 Query: 397 SHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERR 456 R N +++G+P K+ + V A + +G GL + Sbjct: 188 --RRTKNNPVLIGEPGVGKTAI---VEGLAQRIV----KGDVPEGL-------KGKRIVS 231 Query: 457 LEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVME-QQTVTIAKAGIHTTLNARCS--VI 513 L+ G+++ G EF+ + + I EV++ Q V + +HT + A + + Sbjct: 232 LQMGSLL---AGAKYRGEFE---ERLKAVIQEVVQSQGEVILFIDELHTVVGAGKAEGAV 285 Query: 514 AAAN---PVFGQYD------VNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEH 564 A N P + + D ++ I +L RF ++V D+ SI Sbjct: 286 DAGNMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYV--DEPTVEETISILRG 343 Query: 565 VLRTHRYLPPGYLEGEPVRERLNLSLAVGE-----DADINPEEHSNSGAGVENEGEDDED 619 + + + + LS D I+ + + + + E +E Sbjct: 344 LKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAPEEI 403 Query: 620 HVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVI 679 E+ L+ + K + + + E K + + + AK R + +E + + Sbjct: 404 DALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWEREREILRKL 463 Query: 680 VKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVA-------ANL 732 + R D+ ++ + R + L R A +R + A A Sbjct: 464 RE--AQHRLDEVRREIELAERQYD-LNRAAE----LRYGELPKLEAEVEALSEKLRGARF 516 Query: 733 LRFALLGEDIG 743 +R + EDI Sbjct: 517 VRLEVTEEDIA 527 >6CLZ-B nrPDB Length = 211 Score = 29.4 bits (64), Expect = 8.4, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 58/170 (34%), Gaps = 11/170 (6%) Query: 579 GEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKN 638 +E L + +D + + + + +++ + +K P L K + Sbjct: 19 DNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPYLDDFQKKWQE 78 Query: 639 KGNYNGTEIPKLVT--IPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSP 696 + ++ L R+ + +E++ P L +E + + LR Sbjct: 79 EMELYRQKVEPLRAELQEGARQKLHELQEKLSP-LGEEMRDRARAHVDALRTHLAPYSDE 137 Query: 697 ITAR---TLETL-----IRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 738 + R LE L RLA HAK + AK A LR LL Sbjct: 138 LRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLL 187 >3VH5-A nrPDB Length = 140 Score = 29.4 bits (64), Expect = 8.7, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 25/88 (28%), Gaps = 3/88 (3%) Query: 644 GTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLE 703 G+E L +Q + V A +V S IT R E Sbjct: 1 GSEAAGGEQRELL---IQRLRAAVHYTTGALAQDVAEDKGVLFSKQTVAAISEITFRQAE 57 Query: 704 TLIRLATAHAKVRLSKTVNKVDAKVAAN 731 R A+ T+ D K+ A Sbjct: 58 NFARDLEMFARHAKRSTITSEDVKLLAR 85 >5JHF-C nrPDB Length = 413 Score = 29.4 bits (64), Expect = 8.9, Method: Composition-based stats. Identities = 39/248 (15%), Positives = 81/248 (32%), Gaps = 5/248 (2%) Query: 517 NPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGY 576 N + Q++ + L S+ + + + + E R + + L Sbjct: 111 NEIDQQHNSKLGDFISRDSSHILDSKLNEIPTIRKQV-ENITRQYQTMLAKVQSQLVESR 169 Query: 577 LEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLA 636 ++G E+ +N EE +N +E E D + F+ ++ Sbjct: 170 MKGLRDEFSSKFGDQCRENLKLN-EEFTNEADQLEQELADFLKSFTDHFDKCSALSSRSV 228 Query: 637 KNKGNYNGTEIPKLVTIPF--LRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKK 694 + N EI + + +Q A V + + + + ++ + K Sbjct: 229 SPEDAQNLFEIVERDDKDLAAINSLLQDAAIDVASFVRKVNMLLDERDADKAKMQATLSK 288 Query: 695 SPITARTLETLIRLATAH-AKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEY 753 R E I + A ++ K D + NLL F E +++ +E Sbjct: 289 LLTELRKHEEYISVFEGISALIQKFKASCLEDIRQTRNLLDFYANFERSYHNLLKEVKRR 348 Query: 754 EEALSKRS 761 +E +K S Sbjct: 349 KETAAKLS 356 >2D2N-C nrPDB Length = 147 Score = 29.0 bits (63), Expect = 9.4, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 27/73 (36%), Gaps = 9/73 (12%) Query: 366 SLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRG---------DINILMVGDPSTAKS 416 +LA +++ + A L GV + + + R D+ I M+ DP+ Sbjct: 30 ALAQAVFASLFSRDAAAQGLFSGVSADNPDSADFRAHCVRVVNGLDVAINMLNDPAVLNE 89 Query: 417 QLLRFVLNTASLA 429 QL + A Sbjct: 90 QLAHLSAQHQARA 102 >3B0B-B nrPDB Length = 107 Score = 29.0 bits (63), Expect = 9.9, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 24/88 (27%), Gaps = 3/88 (3%) Query: 644 GTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLE 703 G+E L +Q + V +V S IT R E Sbjct: 1 GSEAAGGEQRELL---IQRLRAAVHYTTGCLCQDVAEDKGVLFSKQTVAAISEITFRQCE 57 Query: 704 TLIRLATAHAKVRLSKTVNKVDAKVAAN 731 R A+ T+ D K+ A Sbjct: 58 NFARDLEMFARHAKRSTITSEDVKLLAR 85 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.122 0.305 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,029,469 Number of Sequences: 36641 Number of extensions: 1306762 Number of successful extensions: 3534 Number of sequences better than 10.0: 62 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 60 Number of HSP's that attempted gapping in prelim test: 3363 Number of HSP's gapped (non-prelim): 140 length of query: 971 length of database: 10,336,785 effective HSP length: 106 effective length of query: 865 effective length of database: 6,452,839 effective search space: 5581705735 effective search space used: 5581705735 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.4 bits)