BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24268 (407 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5UX4-A nrPDB 796 0.0 4OC6-B nrPDB 431 e-121 1TZS-A nrPDB 353 6e-98 5N71-A nrPDB 342 1e-94 5MLG-A nrPDB 337 5e-93 5MKT-A nrPDB 336 9e-93 2PSG-A nrPDB 333 1e-91 4AMT-A nrPDB 332 1e-91 1SMR-A nrPDB 327 4e-90 4PEP-A nrPDB 325 2e-89 3VCM-A nrPDB 321 5e-88 5NFG-A nrPDB 320 7e-88 1PSO-E nrPDB 318 3e-87 1AM5-A nrPDB 297 5e-81 4AA9-A nrPDB 297 6e-81 4CMS-A nrPDB 286 8e-78 1FMX-A nrPDB 283 1e-76 1AVF-A nrPDB 270 6e-73 1QDM-A nrPDB 248 2e-66 1B5F-A nrPDB 207 9e-54 4OD9-A nrPDB 200 9e-52 5BWY-A nrPDB 189 2e-48 1XDH-A nrPDB 189 3e-48 2BJU-A nrPDB 188 3e-48 3QS1-A nrPDB 187 5e-48 5I70-B nrPDB 181 4e-46 5JOD-A nrPDB 181 5e-46 2ANL-A nrPDB 179 1e-45 3O9L-A nrPDB 178 4e-45 1MIQ-A nrPDB 173 1e-43 1QS8-A nrPDB 171 7e-43 3OAD-B nrPDB 153 1e-37 1UH8-A nrPDB 143 1e-34 3FNT-A nrPDB 140 1e-33 3QVI-A nrPDB 140 1e-33 3LIZ-A nrPDB 123 1e-28 1WKR-A nrPDB 112 4e-25 3ZKX-A nrPDB 110 9e-25 2ASI-A nrPDB 109 2e-24 3TPL-A nrPDB 102 2e-22 1MPP-A nrPDB 100 1e-21 3FV3-A nrPDB 98 6e-21 2QZW-A nrPDB 96 3e-20 4Y9W-A nrPDB 94 7e-20 1J71-A nrPDB 92 4e-19 3PVK-A nrPDB 89 2e-18 4B1C-A nrPDB 88 7e-18 1B5F-B nrPDB 87 1e-17 1IBQ-A nrPDB 84 1e-16 2H6T-A nrPDB 81 8e-16 1IZE-A nrPDB 80 1e-15 2QZX-A nrPDB 80 2e-15 5HCT-A nrPDB 79 3e-15 1PPK-E nrPDB 79 4e-15 3PI0-A nrPDB 77 1e-14 4ZL4-A nrPDB 55 4e-08 3EMY-A nrPDB 52 6e-07 6CT6-A nrPDB 30 1.3 4QAQ-A nrPDB 30 1.7 4KQP-A nrPDB 28 5.6 >5UX4-A nrPDB Length = 420 Score = 796 bits (2057), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/407 (96%), Positives = 393/407 (96%), Gaps = 1/407 (0%) Query: 1 MQTPGVLLLILGLLDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS 60 M+ V L L + S LIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS Sbjct: 1 MEWSWVFLFFLSVTTGVHS-LIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS 59 Query: 61 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 120 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH Sbjct: 60 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 119 Query: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 180 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ Sbjct: 120 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 179 Query: 181 PGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 240 PGVVFIAAKFDGILGMGYPFISVN VLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL Sbjct: 180 PGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 239 Query: 241 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV 300 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV Sbjct: 240 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV 299 Query: 301 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 360 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI Sbjct: 300 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 359 Query: 361 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL Sbjct: 360 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 406 >4OC6-B nrPDB Length = 243 Score = 431 bits (1107), Expect = e-121, Method: Compositional matrix adjust. Identities = 204/243 (83%), Positives = 223/243 (91%) Query: 165 GGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIF 224 GG+KVE+Q+FGEATKQPG+ FIAAKFDGILGM YP ISVN VLPVFDNLM+QKLV++NIF Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIF 60 Query: 225 SFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGG 284 SFYL+RDP QPGGELMLGGTDS+YY G LSYLNVTRKAYWQVH+DQ+EV S LTLCK G Sbjct: 61 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 120 Query: 285 CEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYEL 344 CEAIVDTGTSL+VGPVDEV+ELQKAIGAVPLIQGEYMIPCEKVS+LP IT KLGG+ Y+L Sbjct: 121 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 180 Query: 345 HPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 PE Y LKVSQAGKT+CLSGFMGMDIPPPSGPLWILGDVFIG YYTVFDR+ NRVGFA+A Sbjct: 181 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 Query: 405 ATL 407 A L Sbjct: 241 ARL 243 >1TZS-A nrPDB Length = 351 Score = 353 bits (907), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 172/341 (50%), Positives = 228/341 (66%), Gaps = 9/341 (2%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 + E L NYLD +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H ++ Sbjct: 10 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRF 67 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV 183 +SSTY + G SF I YG+GSLSG + D VSV G+ V Q FGE+ +PG Sbjct: 68 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVE------GLTVVGQQFGESVTEPGQ 121 Query: 184 VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLG 243 F+ A+FDGILG+GYP ++V V PVFDN+M Q LV+ +FS Y++ +P G G EL+ G Sbjct: 122 TFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFG 181 Query: 244 GTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEV 303 G D ++ G L+++ VT++AYWQ+ +D ++VG + C GC+AIVDTGTSL+ GP D++ Sbjct: 182 GYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI 241 Query: 304 KELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLS 363 K+LQ AIGA P + GEY + C ++ +P +TF + G Y L P Y L G C S Sbjct: 242 KQLQNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 300 Query: 364 GFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 GF G+DI PP+GPLWILGDVFI +Y+VFDR NRVG A A Sbjct: 301 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 341 >5N71-A nrPDB Length = 345 Score = 342 bits (878), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 173/346 (50%), Positives = 235/346 (67%), Gaps = 17/346 (4%) Query: 66 PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNS 125 P E L N LD YYG I IGTPPQ F V+FDTGS+NLW+PS C C HH+Y+S Sbjct: 5 PYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTK--YCLHHHRYDS 62 Query: 126 DKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVF 185 KSSTY +G +F I YGSG++ G++S+D C+ +G KV Q GEA G Sbjct: 63 SKSSTYEADGRNFTIVYGSGNVEGFISKDV----CR--IGSAKVSGQPLGEALVVGGESL 116 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLV-EKNIFSFYLNRDPTGQPGGELMLGG 244 + A FDGILG+ YP I+V+ V+PVFDN+MKQ L+ E+N+FS YLNRDP+ + GGE++ GG Sbjct: 117 LEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGG 176 Query: 245 TDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT-----LCKGGCEAIVDTGTSLLVGP 299 D +Y G ++Y+ VT K YWQ H+D ++ S LCK GCEAI +TGTSL+ GP Sbjct: 177 IDHDHYKGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGP 236 Query: 300 VDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKT 359 +EV L + +G G+Y++ C+K+ SLP +TF + G+ + L + Y+LKV+Q G+T Sbjct: 237 PEEVDSLNQYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQT 296 Query: 360 ICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +C+SGFMG+++P PLWILGDVF+G YYT+FDR+ +RVGFA+ A Sbjct: 297 LCVSGFMGLEMPQ---PLWILGDVFLGPYYTIFDRDQDRVGFAEVA 339 >5MLG-A nrPDB Length = 389 Score = 337 bits (865), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 173/392 (44%), Positives = 250/392 (63%), Gaps = 13/392 (3%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILK-GPITKYSMQSSPRTKEPVSELLK 72 L +++ RI L+K S+R + E G + + + G K S S PV +L Sbjct: 1 LPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKS--SFTNVTSPV--VLT 56 Query: 73 NYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYV 132 NYLD QYYGEIGIGTP Q F V+FDTGS+NLWVPS C L AC +H+ Y+S +SS+Y+ Sbjct: 57 NYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYM 116 Query: 133 KNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDG 192 +NGT F IHYGSG + G+LSQD V+V GGI V Q FGE T+ P + F+ AKFDG Sbjct: 117 ENGTEFTIHYGSGKVKGFLSQDVVTV------GGIIV-TQTFGEVTELPLIPFMLAKFDG 169 Query: 193 ILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHG 252 +LGMG+P +V+ V+PVFD+++ Q+++++ +FS Y +R+ + GGE++LGG+D ++Y G Sbjct: 170 VLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRE-SHLLGGEVVLGGSDPQHYQG 228 Query: 253 ELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGA 312 Y+++++ WQ+ M + VG LC+ GC A+VDTGTS + GP ++ + +A+G Sbjct: 229 NFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGV 288 Query: 313 VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPP 372 Y++ C +V +LP I+F LGG+ Y L Y+ K +C+ G+DIPP Sbjct: 289 KEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPP 348 Query: 373 PSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 P+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 349 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 380 >5MKT-A nrPDB Length = 389 Score = 336 bits (862), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 176/392 (44%), Positives = 246/392 (62%), Gaps = 13/392 (3%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILK-GPITKYSMQSSPRTKEPVSELLK 72 L ++ RIPL+K S+R + E G + L + G TK S PV +L Sbjct: 1 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTK--RPSLTNLTSPV--VLT 56 Query: 73 NYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYV 132 NYL+ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC +H Y S SS+Y+ Sbjct: 57 NYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYM 116 Query: 133 KNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDG 192 +NG+ F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ P + F+ AKFDG Sbjct: 117 ENGSDFTIHYGSGRVKGFLSQDSVTV------GGITV-TQTFGEVTELPLIPFMLAKFDG 169 Query: 193 ILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHG 252 +LGMG+P +V V PVFD+++ Q ++++ +FS Y NR + GGE++LGG+D ++Y G Sbjct: 170 VLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQG 228 Query: 253 ELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGA 312 Y+++++ WQ+ M + VGS LC+ GC +VDTG+S + P +K + +A+GA Sbjct: 229 NFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 288 Query: 313 VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPP 372 EY++ C +V +LP I+F LGG+ Y L Y+L+ +C MDIPP Sbjct: 289 KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPP 348 Query: 373 PSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 P+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 349 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 380 >2PSG-A nrPDB Length = 370 Score = 333 bits (853), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 177/388 (45%), Positives = 236/388 (60%), Gaps = 21/388 (5%) Query: 21 LIRIPLRKFTSIRRTMTEVGGSVEDLIL---KGPITKYSMQSSPRTKEPVSELLKNYLDA 77 L+++PL + S+R+ + + G ++D + P +KY +++ + E L+NYLD Sbjct: 1 LVKVPLVRKKSLRQNLIK-DGKLKDFLKTHKHNPASKYFPEAAALIGD---EPLENYLDT 56 Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 +Y+G IGIGTP Q FTV+FDTGSSNLWVPS++C L AC H+++N D SST+ Sbjct: 57 EYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDSSTFEATSQE 114 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMG 197 I YG+GS++G L DTV V GGI QIFG + +PG A FDGILG+ Sbjct: 115 LSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYAPFDGILGLA 168 Query: 198 YPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYL 257 YP IS + PVFDNL Q LV +++FS YL+ + G ++LGG DS YY G L+++ Sbjct: 169 YPSISASGATPVFDNLWDQGLVSQDLFSVYLSSND--DSGSVVLLGGIDSSYYTGSLNWV 226 Query: 258 NVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQ 317 V+ + YWQ+ +D + + E C GGC+AIVDTGTSLL GP + +Q IGA Sbjct: 227 PVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSD 286 Query: 318 GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPL 377 GE +I C + SLP I F + G Y L P YIL+ + C SGF GMD+P SG L Sbjct: 287 GEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDS----CTSGFEGMDVPTSSGEL 342 Query: 378 WILGDVFIGCYYTVFDREYNRVGFAKAA 405 WILGDVFI YYTVFDR N+VG A A Sbjct: 343 WILGDVFIRQYYTVFDRANNKVGLAPVA 370 >4AMT-A nrPDB Length = 383 Score = 332 bits (852), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 166/393 (42%), Positives = 242/393 (61%), Gaps = 13/393 (3%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKN 73 L ++ RI L++ SIR ++ E G D+ GP M+ S +L N Sbjct: 1 LPTDTTTFKRIFLKRMPSIRESLKERG---VDMARLGPEWSQPMKRLTLGNTTSSVILTN 57 Query: 74 YLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVK 133 Y+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC H +++ SS+Y Sbjct: 58 YMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKH 117 Query: 134 NGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193 NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ P + F+ A+FDG+ Sbjct: 118 NGTELTLRYSTGTVSGFLSQDIITV------GGITV-TQMFGEVTEMPALPFMLAEFDGV 170 Query: 194 LGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQP--GGELMLGGTDSRYYH 251 +GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD GG+++LGG+D ++Y Sbjct: 171 VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYE 230 Query: 252 GELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIG 311 G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S + G +++L +A+G Sbjct: 231 GNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALG 290 Query: 312 AVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIP 371 A + +Y++ C + +LP I+F LGG+ Y L Y+ + S + K +C MDIP Sbjct: 291 AKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIP 349 Query: 372 PPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 PP+GP W LG FI +YT FDR NR+GFA A Sbjct: 350 PPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 382 >1SMR-A nrPDB Length = 335 Score = 327 bits (839), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 160/335 (47%), Positives = 224/335 (66%), Gaps = 8/335 (2%) Query: 70 LLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSS 129 +L NYL++QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC +H Y S SS Sbjct: 8 VLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSS 67 Query: 130 TYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAK 189 +Y++NG F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ P + F+ A+ Sbjct: 68 SYMENGDDFTIHYGSGRVKGFLSQDSVTV------GGITV-TQTFGEVTQLPLIPFMLAQ 120 Query: 190 FDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRY 249 FDG+LGMG+P +V V PVFD+++ Q ++++ +FS Y NR P GGE++LGG+D ++ Sbjct: 121 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPH-LLGGEVVLGGSDPQH 179 Query: 250 YHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKA 309 Y G+ Y+++++ WQ+ M + VGS LC+ GCE +VDTG+S + P +K + +A Sbjct: 180 YQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQA 239 Query: 310 IGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMD 369 +GA EY++ C +V +LP I+F LGG+ Y L Y+L+ +C MD Sbjct: 240 LGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMD 299 Query: 370 IPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 IPPP+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 300 IPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 334 >4PEP-A nrPDB Length = 326 Score = 325 bits (834), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 167/337 (49%), Positives = 210/337 (62%), Gaps = 14/337 (4%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 E L+NYLD +Y+G IGIGTP Q FTV+FDTGSSNLWVPS++C L AC H+++N D S Sbjct: 4 EPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDS 61 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 ST+ I YG+GS++G L DTV V GGI QIFG + +PG A Sbjct: 62 STFEATSQELSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYA 115 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 FDGILG+ YP IS + PVFDNL Q LV +++FS YL+ + G ++LGG DS Sbjct: 116 PFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSND--DSGSVVLLGGIDSS 173 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 YY G L+++ V+ + YWQ+ +D + + E C GGC+AIVDTGTSLL GP + +Q Sbjct: 174 YYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQS 233 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 IGA GE +I C + SLP I F + G Y L P YIL+ + C SGF GM Sbjct: 234 DIGASENSDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDS----CTSGFEGM 289 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 D+P SG LWILGDVFI YYTVFDR N+VG A A Sbjct: 290 DVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA 326 >3VCM-A nrPDB Length = 335 Score = 321 bits (822), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 153/337 (45%), Positives = 221/337 (65%), Gaps = 11/337 (3%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 S +L NY+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC H +++ Sbjct: 9 SVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASD 68 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIA 187 SS+Y NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ P + F+ Sbjct: 69 SSSYKHNGTELTLRYSTGTVSGFLSQDIITV------GGITV-TQMFGEVTEMPALPFML 121 Query: 188 AKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDS 247 A+FDG++GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD GG+++LGG+D Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSL---GGQIVLGGSDP 178 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 ++Y G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S + G +++L Sbjct: 179 QHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLM 238 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 +A+GA + +Y++ C + +LP I+F LGG+ Y L Y+ + S + K +C Sbjct: 239 EALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHA 297 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 MDIPPP+GP W LG FI +YT FDR NR+GFA A Sbjct: 298 MDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 334 >5NFG-A nrPDB Length = 383 Score = 320 bits (820), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 168/390 (43%), Positives = 236/390 (60%), Gaps = 12/390 (3%) Query: 17 SSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLD 76 S+ L+R+ L+K R G +L + + + R L N D Sbjct: 3 SNGGLLRVGLKKRKVDRLDQLRAHGV---HMLGNARKDFGFRRTLRDSGSGIVALTNDRD 59 Query: 77 AQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGT 136 YYGEIGIGTPPQ F V+FDTGSS+LWVPS C +AC +H +Y+S SSTY NGT Sbjct: 60 TAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKCDT-SLACVIHPRYDSGDSSTYKGNGT 118 Query: 137 SFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGM 196 + I YG+G++ G+ SQD+V V G + VE Q F E T++ VF+ ++FDGILG+ Sbjct: 119 TASIQYGTGAIVGFYSQDSVEV------GDLVVEHQDFIETTEEDDTVFLKSEFDGILGL 172 Query: 197 GYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSY 256 G+ IS K +PV+ N++ Q LVE+ +FSF+LNR+ + GGEL+ GG D ++ G +Y Sbjct: 173 GFQEISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTY 232 Query: 257 LNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAV-P 314 + VTRK YWQ M + +G + + C GGC AI D+GTS GP + ++ +AIGA Sbjct: 233 VPVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGG 292 Query: 315 LIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPS 374 E ++ C +SS+P I F +G + +E+ PE+YI KV + C+SGF +DI P Sbjct: 293 GGSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQ 352 Query: 375 GPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 GP+WILGD+F+G Y+TVFD RVGFA+A Sbjct: 353 GPIWILGDMFMGPYHTVFDYGKLRVGFAEA 382 >1PSO-E nrPDB Length = 326 Score = 318 bits (815), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 163/335 (48%), Positives = 211/335 (62%), Gaps = 14/335 (4%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L+NYLD +Y+G IGIGTP Q FTVVFDTGSSNLWVPS++C L AC H+++N + SST Sbjct: 6 LENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSL--ACTNHNRFNPEDSST 63 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 Y + I YG+GS++G L DTV V GGI QIFG + +PG A F Sbjct: 64 YQSTSETVSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYAPF 117 Query: 191 DGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYY 250 DGILG+ YP IS + PVFDN+ Q LV +++FS YL+ D Q G ++ GG DS YY Sbjct: 118 DGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD--QSGSVVIFGGIDSSYY 175 Query: 251 HGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAI 310 G L+++ VT + YWQ+ +D + + E C GC+AIVDTGTSLL GP + +Q I Sbjct: 176 TGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDI 235 Query: 311 GAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDI 370 GA G+ ++ C +SSLP I F + G Y + P YIL+ + C+SGF GM++ Sbjct: 236 GASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGS----CISGFQGMNL 291 Query: 371 PPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 P SG LWILGDVFI Y+TVFDR N+VG A A Sbjct: 292 PTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA 326 >1AM5-A nrPDB Length = 324 Score = 297 bits (761), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 160/339 (47%), Positives = 206/339 (60%), Gaps = 16/339 (4%) Query: 67 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 126 V+E +KN D +YYG I IGTPP+ F V+FDTGSSNLWV S HC AC H+K+ Sbjct: 2 VTEQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQ--ACSNHNKFKPR 59 Query: 127 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI 186 +SSTYV+ G + D+ YG+G + G L QDTVSV GG Q GE+ +PG Sbjct: 60 QSSTYVETGKTVDLTYGTGGMRGILGQDTVSV------GGGSDPNQELGESQTEPGPFQA 113 Query: 187 AAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 AA FDGILG+ YP I+ +PVFDN+ Q LVEK++FSFYL+ G G E+MLGG D Sbjct: 114 AAPFDGILGLAYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGG--GANGSEVMLGGVD 171 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 + +Y G + ++ VT + YWQV +D + V + C+ GC+AIVDTGTS +V PV + + Sbjct: 172 NSHYTGSIHWIPVTAEKYWQVALDGITVNGQTAACE-GCQAIVDTGTSKIVAPVSALANI 230 Query: 307 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 K IGA QGE M C V SLP ITF + G L P YI + + C SG Sbjct: 231 MKDIGASEN-QGEMMGNCASVQSLPDITFTINGVKQPLPPSAYI----EGDQAFCTSGLG 285 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +P + LWI GDVF+ YYT++DR N+VGFA AA Sbjct: 286 SSGVPSNTSELWIFGDVFLRNYYTIYDRTNNKVGFAPAA 324 >4AA9-A nrPDB Length = 320 Score = 297 bits (760), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 157/336 (46%), Positives = 213/336 (63%), Gaps = 19/336 (5%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 E L +YLD+QY+G+I IGTPPQ FTVVFDTGSS+LWVPSI+CK C HH+++ KS Sbjct: 3 EPLTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCK--SNVCKNHHRFDPRKS 60 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 ST+ G IHYG+GS+ G+L DTV+V I Q G +T+QPG VF + Sbjct: 61 STFRNLGKPLSIHYGTGSMEGFLGYDTVTV------SNIVDPNQTVGLSTEQPGEVFTYS 114 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 +FDGILG+ YP ++ +PVFDN+M + LV +++FS Y++R+ GQ G L LG D Sbjct: 115 EFDGILGLAYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRN--GQ-GSMLTLGAIDPS 171 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 YY G L ++ VT + YWQ +D + + C GGC+AI+DTGTS+L GP ++ ++Q Sbjct: 172 YYTGSLHWVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQM 231 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 AIGA GE+ + C + S+P + F++ G++Y L P Y K + C SGF G Sbjct: 232 AIGATENRYGEFDVNCGNLRSMPTVVFEINGRDYPLSPSAYTSK----DQGFCTSGFQGD 287 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + + LWILGDVFI YY+VFDR NRVG AKA Sbjct: 288 N----NSELWILGDVFIREYYSVFDRANNRVGLAKA 319 >4CMS-A nrPDB Length = 323 Score = 286 bits (733), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 154/340 (45%), Positives = 211/340 (62%), Gaps = 19/340 (5%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYN 124 E S L NYLD+QY+G+I +GTPPQ FTV+FDTGSS+ WVPSI+CK AC H +++ Sbjct: 2 EVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK--SNACKNHQRFD 59 Query: 125 SDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVV 184 KSST+ G IHYG+GS+ G L DTV+V D+ +Q G +T++PG V Sbjct: 60 PRKSSTFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDI------QQTVGLSTQEPGDV 113 Query: 185 FIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGG 244 F A+FDGILGM YP ++ +PVFDN+M + LV +++FS Y++R+ GQ L LG Sbjct: 114 FTYAEFDGILGMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRN--GQES-MLTLGA 170 Query: 245 TDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVK 304 D YY G L ++ VT + YWQ +D + + + C+GGC+AI+DTGTS LVGP ++ Sbjct: 171 IDPSYYTGSLHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDIL 230 Query: 305 ELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSG 364 +Q+AIGA GE+ I C+ +S +P + F++ G+ Y L P Y + + C SG Sbjct: 231 NIQQAIGATQNQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAY----TSQDQGFCTSG 286 Query: 365 FMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 F + WILGDVFI YY+VFDR N VG AKA Sbjct: 287 FQSEN----HSQKWILGDVFIREYYSVFDRANNLVGLAKA 322 >1FMX-A nrPDB Length = 329 Score = 283 bits (723), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 151/335 (45%), Positives = 206/335 (61%), Gaps = 14/335 (4%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L NYL+AQYY +I +GTPPQ F V+ DTGSSNLWVPS C L AC++H KY+ + SS+ Sbjct: 7 LTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSL--ACFLHSKYDHEASSS 64 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 Y NGT F I YG+GSL GY+SQDT+S+ G + + KQ F EAT +PG+ F KF Sbjct: 65 YKANGTEFAIQYGTGSLEGYISQDTLSI------GDLTIPKQDFAEATSEPGLTFAFGKF 118 Query: 191 DGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYL-NRDPTGQPGGELMLGGTDSRY 249 DGILG+GY ISV+KV+P F N ++Q L+++ F+FYL + + GGE GG D Sbjct: 119 DGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESK 178 Query: 250 YHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKA 309 + G++++L V RKAYW+V + + +G E + AI DTGTSL+ P + + Sbjct: 179 FKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAI-DTGTSLITLPSGLAEMINAE 237 Query: 310 IGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMD 369 IGA G+Y + C +LP + F G N+ + P Y L+VS + C+S MD Sbjct: 238 IGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGS----CISAITPMD 293 Query: 370 IPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 P P GPL I+GD F+ YY+++D N VG AKA Sbjct: 294 FPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKA 328 >1AVF-A nrPDB Length = 329 Score = 270 bits (691), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 143/345 (41%), Positives = 209/345 (60%), Gaps = 20/345 (5%) Query: 63 TKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHK 122 T EP++ Y+DA Y+GEI IGTPPQ F V+FDTGSSNLWVPS++C+ AC H + Sbjct: 3 TYEPMA-----YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSR 55 Query: 123 YNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPG 182 +N +SSTY NG +F + YGSGSL+G+ DT++V I+V Q FG + +PG Sbjct: 56 FNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQS------IQVPNQEFGLSENEPG 109 Query: 183 VVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELML 242 F+ A+FDGI+G+ YP +SV++ ++++ + +FS YL+ G GG ++ Sbjct: 110 TNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQ-QGSSGGAVVF 168 Query: 243 GGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVD 301 GG DS Y G++ + VT++ YWQ+ +++ +G + + C GC+AIVDTGTSLL P Sbjct: 169 GGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQ 228 Query: 302 EVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTIC 361 + L +A GA G++++ C + +LP +TF + G + L P YIL + C Sbjct: 229 YMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYIL----SNNGYC 284 Query: 362 LSGFMGMDIPPPSG-PLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 G + +G PLWILGDVF+ YY+V+D NRVGFA AA Sbjct: 285 TVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA 329 >1QDM-A nrPDB Length = 478 Score = 248 bits (634), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 142/303 (46%), Positives = 194/303 (64%), Gaps = 20/303 (6%) Query: 22 IRIPLRKFTSIR--RTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSEL--LKNYLDA 77 +RI L+K R R T + G E +L G ++P E ++ LKNY++A Sbjct: 1 VRIALKKRPIDRNSRVATGLSGGEEQPLLSG--------ANPLRSEEEGDIVALKNYMNA 52 Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H +Y + SSTY KNG Sbjct: 53 QYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKC-YFSIACYLHSRYKAGASSTYKKNGKP 111 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMG 197 I YG+GS++GY S+D+V+V G + V+ Q F EATK+PG+ F+ AKFDGILG+G Sbjct: 112 AAIQYGTGSIAGYFSEDSVTV------GDLVVKDQEFIEATKEPGITFLVAKFDGILGLG 165 Query: 198 YPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYL 257 + ISV K +PV+ +++Q LV +FSF+LNR GGE++ GG D ++Y GE +Y+ Sbjct: 166 FKEISVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYV 225 Query: 258 NVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLI 316 VT+K YWQ M + VG + T C GGC AI D+GTSLL GP + E+ + IGA ++ Sbjct: 226 PVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAAGVV 285 Query: 317 QGE 319 E Sbjct: 286 SQE 288 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 51/93 (54%), Positives = 64/93 (68%) Query: 313 VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPP 372 +P GE + C + S+P I F +GG+ + L PE+YILKV + C+SGF MDIPP Sbjct: 386 LPSPMGESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQCISGFTAMDIPP 445 Query: 373 PSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 P GPLWILGDVF+G Y+TVFD R+GFAKAA Sbjct: 446 PRGPLWILGDVFMGPYHTVFDYGKLRIGFAKAA 478 >1B5F-A nrPDB Length = 239 Score = 207 bits (526), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 114/243 (46%), Positives = 155/243 (63%), Gaps = 12/243 (4%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L N D Y+GEIGIGTPPQ FTV+FDTGSS LWVPS C + AC H Y S SST Sbjct: 7 LTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKC-INSKACRAHSMYESSDSST 65 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 Y +NGT I YG+GS++G+ SQD+V++ G + V++Q F EAT + VF+ F Sbjct: 66 YKENGTFGAIIYGTGSITGFFSQDSVTI------GDLVVKEQDFIEATDEADNVFLHRLF 119 Query: 191 DGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYY 250 DGILG+ + ISV PV+ N++ Q LV++ FSF+LNR+ + GGEL+ GG D ++ Sbjct: 120 DGILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHF 175 Query: 251 HGELSYLNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEVKELQKA 309 G+ +Y+ VT + YWQ + + +G + T C GC+A D+GTSLL GP V ++ A Sbjct: 176 RGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHA 235 Query: 310 IGA 312 IGA Sbjct: 236 IGA 238 >4OD9-A nrPDB Length = 103 Score = 200 bits (508), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 92/100 (92%), Positives = 98/100 (98%) Query: 63 TKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHK 122 T+ P+ E+LKNY+DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW+HHK Sbjct: 4 TEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHK 63 Query: 123 YNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKS 162 YNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPC+S Sbjct: 64 YNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 103 >5BWY-A nrPDB Length = 376 Score = 189 bits (479), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 116/337 (34%), Positives = 181/337 (53%), Gaps = 22/337 (6%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C H Y+S KS T Sbjct: 55 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKHLYDSSKSRT 112 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +++Y SG++SG+ S+D V+V G + + + F E G + A+ Sbjct: 113 YEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEVIDTNGFEPTYTAS 165 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPT-GQPGGELMLGGTDS 247 FDGILG+G+ +S+ V P+ L Q +E +F+FYL P + G L +GG + Sbjct: 166 TFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYL---PVHDKHTGFLTIGGIEE 222 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 R+Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS + P D + ++ Sbjct: 223 RFYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSAITVPTDFLNKML 278 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 + + + + + + S LP F Y L PE Y+ + G +C+ +G Sbjct: 279 QNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIG 338 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 339 LDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALA 372 >1XDH-A nrPDB Length = 331 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 116/337 (34%), Positives = 181/337 (53%), Gaps = 22/337 (6%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C H Y+S KS T Sbjct: 10 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKHLYDSSKSRT 67 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +++Y SG++SG+ S+D V+V G + + + F E G + A+ Sbjct: 68 YEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEVIDTNGFEPTYTAS 120 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPT-GQPGGELMLGGTDS 247 FDGILG+G+ +S+ V P+ L Q +E +F+FYL P + G L +GG + Sbjct: 121 TFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYL---PVHDKHTGFLTIGGIEE 177 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 R+Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS + P D + ++ Sbjct: 178 RFYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSAITVPTDFLNKML 233 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 + + + + + + S LP F Y L PE Y+ + G +C+ +G Sbjct: 234 QNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIG 293 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 294 LDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALA 327 >2BJU-A nrPDB Length = 453 Score = 188 bits (478), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 116/337 (34%), Positives = 181/337 (53%), Gaps = 22/337 (6%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C H Y+S KS T Sbjct: 132 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKHLYDSSKSRT 189 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +++Y SG++SG+ S+D V+V G + + + F E G + A+ Sbjct: 190 YEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEVIDTNGFEPTYTAS 242 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPT-GQPGGELMLGGTDS 247 FDGILG+G+ +S+ V P+ L Q +E +F+FYL P + G L +GG + Sbjct: 243 TFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYL---PVHDKHTGFLTIGGIEE 299 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 R+Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS + P D + ++ Sbjct: 300 RFYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSAITVPTDFLNKML 355 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 + + + + + + S LP F Y L PE Y+ + G +C+ +G Sbjct: 356 QNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIG 415 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 416 LDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALA 449 >3QS1-A nrPDB Length = 336 Score = 187 bits (476), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 120/340 (35%), Positives = 184/340 (54%), Gaps = 22/340 (6%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 S L + + YYGE IG Q F +FDTGS+NLWVPS C I C + Y+S+K Sbjct: 12 SVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNT--IGCKTKNLYDSNK 69 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VF 185 S TY K+GT +++Y SG++SG+ S+D V++ S F E T G + Sbjct: 70 SKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLS-------FPYKFIEVTDTNGFEPAY 122 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 +FDGI+G+G+ +S+ V PV L Q +E+ +F+FYL D + G L +GG Sbjct: 123 TLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHK--GYLTIGGI 180 Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKE 305 + R+Y G+L+Y + YWQV +D L G+ LT+ K AIVD+GTS + P + + + Sbjct: 181 EDRFYEGQLTYEKLNHDLYWQVDLD-LHFGN-LTVEK--ATAIVDSGTSSITAPTEFLNK 236 Query: 306 LQKAIGAVPL-IQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSG 364 + + V + Y+ C LP + F+ Y L PE Y+ ++ G ++C+ Sbjct: 237 FFEGLDVVKIPFLPLYITTCNN-PKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLCMVS 295 Query: 365 FMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + +D+ + +ILGD F+ Y+TVFD + + VGFA A Sbjct: 296 IIPVDLNKNT---FILGDPFMRKYFTVFDYDNHTVGFALA 332 >5I70-B nrPDB Length = 328 Score = 181 bits (460), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 117/342 (34%), Positives = 180/342 (52%), Gaps = 26/342 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE IGT Q F +FDTGS+NLWVPS++C I C H Y++ S + Sbjct: 8 LDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCD--SIGCSTKHLYDASASKS 65 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +I YGSG++ GY S+D +S LG + + + F E T + ++ + Sbjct: 66 YEKDGTKVEISYGSGTVRGYFSKDVIS------LGDLSLPYK-FIEVTDADDLEPIYSGS 118 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPG-GELMLGGTDS 247 +FDGILG+G+ +S+ + PV L KQ ++ +F+FYL P G L +GG +S Sbjct: 119 EFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYL---PVHDKHVGYLTIGGIES 175 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 +Y G L+Y + YWQ+ +D + G + A+VD+GTS + P + + Sbjct: 176 DFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFF 231 Query: 308 KAIGA--VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + + VP + Y+ C+ LP + F Y L PE Y+ +S +C+ Sbjct: 232 RDMNVIKVPFLP-LYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYI 289 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 + +DI + +ILGD F+ Y+TVFD E VGFA A L Sbjct: 290 LPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAKNL 328 >5JOD-A nrPDB Length = 375 Score = 181 bits (459), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 117/342 (34%), Positives = 180/342 (52%), Gaps = 26/342 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE IGT Q F +FDTGS+NLWVPS++C I C H Y++ S + Sbjct: 55 LDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCD--SIGCSTKHLYDASASKS 112 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +I YGSG++ GY S+D +S LG + + + F E T + ++ + Sbjct: 113 YEKDGTKVEISYGSGTVRGYFSKDVIS------LGDLSLPYK-FIEVTDADDLEPIYSGS 165 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPG-GELMLGGTDS 247 +FDGILG+G+ +S+ + PV L KQ ++ +F+FYL P G L +GG +S Sbjct: 166 EFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYL---PVHDKHVGYLTIGGIES 222 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 +Y G L+Y + YWQ+ +D + G + A+VD+GTS + P + + Sbjct: 223 DFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFF 278 Query: 308 KAIGA--VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + + VP + Y+ C+ LP + F Y L PE Y+ +S +C+ Sbjct: 279 RDMNVIKVPFLP-LYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYI 336 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 + +DI + +ILGD F+ Y+TVFD E VGFA A L Sbjct: 337 LPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAKNL 375 >2ANL-A nrPDB Length = 327 Score = 179 bits (455), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 112/340 (32%), Positives = 178/340 (52%), Gaps = 28/340 (8%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE +G Q F ++FDTGS+NLWVPS C I C H Y+S KS + Sbjct: 8 LDDVANLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCN--SIGCSTKHLYDSSKSKS 65 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +I YGSG++ G+ S+D V+ LG + + + F E T + ++ AA Sbjct: 66 YEKDGTKVEITYGSGTVRGFFSKDLVT------LGYLSLPYK-FIEVTDTDDLEPLYTAA 118 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPT-GQPGGELMLGGTDS 247 +FDGILG+G+ +S+ + P+ L Q +++ +F+FYL P + G L +GG + Sbjct: 119 EFDGILGLGWKDLSIGSIDPIVVELKNQNKIDQALFTFYL---PVHDKHSGYLTIGGIEE 175 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCE---AIVDTGTSLLVGPVDEVK 304 ++Y GEL+Y + +WQV +D + K E IVD+GTS + P + Sbjct: 176 KFYEGELTYEKLNHDLFWQVDLD-------VNFGKTSMEKANVIVDSGTSTITAPTSFIN 228 Query: 305 ELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSG 364 + K + + + + I +P + FK Y L PE Y+ + T+C+ Sbjct: 229 KFFKDLNVIKVPFLPFYITTCNNKDMPTLEFKSANNTYTLEPEYYMEPLLDIDDTLCMLY 288 Query: 365 FMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + +DI + +ILGD F+ Y+TVFD + +GFA A Sbjct: 289 ILPVDIDKNT---FILGDPFMRKYFTVFDYDKESIGFAVA 325 >3O9L-A nrPDB Length = 166 Score = 178 bits (451), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 83/164 (50%), Positives = 117/164 (71%), Gaps = 7/164 (4%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 S +L NY+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC H +++ Sbjct: 9 SVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASD 68 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIA 187 SS+Y NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ P + F+ Sbjct: 69 SSSYKHNGTELTLRYSTGTVSGFLSQDIITV------GGITV-TQMFGEVTEMPALPFML 121 Query: 188 AKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRD 231 A+FDG++GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 165 >1MIQ-A nrPDB Length = 375 Score = 173 bits (438), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 110/339 (32%), Positives = 181/339 (53%), Gaps = 26/339 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE +G Q F ++FDTGS+NLWVPS C C + + Y+S KS + Sbjct: 56 LDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCN--SSGCSIKNLYDSSKSKS 113 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT DI YGSG++ G+ S+D V+ LG + + + F E T + ++ + Sbjct: 114 YEKDGTKVDITYGSGTVKGFFSKDLVT------LGHLSMPYK-FIEVTDTDDLEPIYSSV 166 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ-PGGELMLGGTDS 247 +FDGILG+G+ +S+ + P+ L Q ++ +F+FYL P G L +GG + Sbjct: 167 EFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFYL---PVHDVHAGYLTIGGIEE 223 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 ++Y G ++Y + YWQ+ +D + G + T+ K IVD+GT+ + P + + + Sbjct: 224 KFYEGNITYEKLNHDLYWQIDLD-VHFGKQ-TMEKAN--VIVDSGTTTITAPSEFLNKFF 279 Query: 308 KAIGA--VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + VP + Y+ C+ +P + FK Y L PE Y+ + + T+C+ Sbjct: 280 ANLNVIKVPFLPF-YVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITM 337 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + +DI + +ILGD F+ Y+TVFD + VGFA A Sbjct: 338 LPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIA 373 >1QS8-A nrPDB Length = 329 Score = 171 bits (432), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 109/339 (32%), Positives = 180/339 (53%), Gaps = 26/339 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE +G Q F ++FDTGS+NLWVPS C C + + Y+S KS + Sbjct: 10 LDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCN--SSGCSIKNLYDSSKSKS 67 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT DI YGSG++ G+ S+D V+ LG + + + F E + ++ + Sbjct: 68 YEKDGTKVDITYGSGTVKGFFSKDLVT------LGHLSMPYK-FIEVIDTDDLEPIYSSV 120 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ-PGGELMLGGTDS 247 +FDGILG+G+ +S+ + P+ L Q ++ +F+FYL P G L +GG + Sbjct: 121 EFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFYL---PVHDVHAGYLTIGGIEE 177 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 ++Y G ++Y + YWQ+ +D + G + T+ K IVD+GT+ + P + + + Sbjct: 178 KFYEGNITYEKLNHDLYWQIDLD-VHFGKQ-TMEKAN--VIVDSGTTTITAPSEFLNKFF 233 Query: 308 KAIGA--VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + VP + Y+ C+ +P + FK Y L PE Y+ + + T+C+ Sbjct: 234 ANLNVIKVPFLPF-YVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITM 291 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + +DI + +ILGD F+ Y+TVFD + VGFA A Sbjct: 292 LPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIA 327 >3OAD-B nrPDB Length = 176 Score = 153 bits (387), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 70/168 (41%), Positives = 104/168 (61%), Gaps = 1/168 (0%) Query: 237 GGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLL 296 GG+++LGG+D ++Y G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S + Sbjct: 3 GGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYI 62 Query: 297 VGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQA 356 G +++L +A+GA + +Y++ C + +LP I+F LGG+ Y L Y+ + S + Sbjct: 63 SGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYS 121 Query: 357 GKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 K +C MDIPPP+GP W LG FI +YT FDR NR+GFA A Sbjct: 122 SKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 169 >1UH8-A nrPDB Length = 325 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 108/334 (32%), Positives = 172/334 (51%), Gaps = 27/334 (8%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHH-KYNSDKSSTYVKN 134 D +YYG++ IGTP + F + FDTGSS+LW+ S C C KY+ ++SSTY + Sbjct: 14 DIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLC----TNCGSRQTKYDPNQSSTYQAD 69 Query: 135 GTSFDIHYGSG-SLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193 G ++ I YG G S SG L++D V +LGG+ ++ Q E K+ F + DG+ Sbjct: 70 GRTWSISYGDGSSASGILAKDNV------NLGGLLIKGQTI-ELAKREAASFASGPNDGL 122 Query: 194 LGMGYPFI-SVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHG 252 LG+G+ I +V V DNL+ Q L+ + IF YL + GGE + GG DS + G Sbjct: 123 LGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGK-AKNGGGGEYIFGGYDSTKFKG 181 Query: 253 ELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIG 311 L+ + + + +W + +D+ VG+ + I+DTGT+LL+ P + + +A G Sbjct: 182 SLTTVPIDNSRGWWGITVDRATVGTSTVASS--FDGILDTGTTLLILPNNIAASVARAYG 239 Query: 312 AVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIP 371 A G Y I C+ P++ F + G ++++ P+ + + Q G+ I G+ D Sbjct: 240 ASDNGDGTYTISCDTSRFKPLV-FSINGASFQVSPDSLVFEEFQ-GQCIAGFGYGNWDFA 297 Query: 372 PPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 I+GD F+ Y VF++ V A A Sbjct: 298 -------IIGDTFLKNNYVVFNQGVPEVQIAPVA 324 >3FNT-A nrPDB Length = 332 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 96/341 (28%), Positives = 171/341 (50%), Gaps = 24/341 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 LK+ + +GE +G Q F +F T SSN+WVPSI C +C + Y+S KS T Sbjct: 12 LKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCT--SESCESKNHYDSSKSKT 69 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+ T + +G++SG S+D V++ G + V + F E T+ G + + Sbjct: 70 YEKDDTPVKLTSKAGTISGIFSKDLVTI------GKLSVPYK-FIEMTEIVGFEPFYSES 122 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 DG+ G+G+ +S+ + P L Q +E+ ++S YL P + G L +GG + R Sbjct: 123 DVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYL--PPENKNKGYLTIGGIEER 180 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL-- 306 ++ G L+Y + WQV +D + G+ + I+D+ TS++ P + + Sbjct: 181 FFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQFVE 236 Query: 307 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 ++ VP + Y+ C + LP + ++ + Y L P++Y+ + +C+ + Sbjct: 237 SASVFKVPFL-SLYVTTCGN-TKLPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIV 294 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 +D+ + ++LGD F+ Y+TV+D + + VGFA A L Sbjct: 295 PIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAKNL 332 >3QVI-A nrPDB Length = 451 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 96/341 (28%), Positives = 171/341 (50%), Gaps = 24/341 (7%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 LK+ + +GE +G Q F +F T SSN+WVPSI C +C + Y+S KS T Sbjct: 131 LKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKC--TSESCESKNHYDSSKSKT 188 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+ T + +G++SG S+D V++ G + V + F E T+ G + + Sbjct: 189 YEKDDTPVKLTSKAGTISGIFSKDLVTI------GKLSVPYK-FIEMTEIVGFEPFYSES 241 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 DG+ G+G+ +S+ + P L Q +E+ ++S YL P + G L +GG + R Sbjct: 242 DVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYL--PPENKNKGYLTIGGIEER 299 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL-- 306 ++ G L+Y + WQV +D + G+ + I+D+ TS++ P + + Sbjct: 300 FFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQFVE 355 Query: 307 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 ++ VP + Y+ C + LP + ++ + Y L P++Y+ + +C+ + Sbjct: 356 SASVFKVPFL-SLYVTTCGN-TKLPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIV 413 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 +D+ + ++LGD F+ Y+TV+D + + VGFA A L Sbjct: 414 PIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAKNL 451 >3LIZ-A nrPDB Length = 334 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 95/342 (27%), Positives = 165/342 (48%), Gaps = 22/342 (6%) Query: 66 PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNS 125 P+ +L+ +++ QY G IG Q F VFD+ S N+ V S C C KY Sbjct: 8 PLYKLVHVFINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEK 65 Query: 126 DKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVF 185 K Y+ +G + +GS G +D++++ S L + + + + Q + Sbjct: 66 LKPK-YISDGNVQVKFFDTGSAVGRGIEDSLTI---SQLTTSQ-QDIVLADELSQEVCIL 120 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 A GI G P + K V +N +++ L+ +FS + R G+ GE++ GG+ Sbjct: 121 SADVVVGIAAPGCP--NALKGKTVLENFVEENLIAP-VFSIHHARFQDGEHFGEIIFGGS 177 Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKE 305 D +Y GE +Y+ + W+ +D +++G + T+ G +AI+DT +++VGP V Sbjct: 178 DWKYVDGEFTYVPLVGDDSWKFRLDGVKIG-DTTVAPAGTQAIIDTSKAIIVGPKAYVNP 236 Query: 306 LQKAIGAV---PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 + +AIG V + + C K+ SLP +TF + G+N+ + + YI Q +C Sbjct: 237 INEAIGCVVEKTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYI----QQNGNLCY 292 Query: 363 SGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 SGF P + +GD F+ YY+ F+ E +GF ++ Sbjct: 293 SGFQ----PCGHSDHFFIGDFFVDHYYSEFNWENKTMGFGRS 330 >1WKR-A nrPDB Length = 340 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 104/353 (29%), Positives = 158/353 (44%), Gaps = 65/353 (18%) Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 Y +G+G+P ++++ DTGSSN W+ +DKS YVK TS Sbjct: 13 DYVVNVGVGSPATTYSLLVDTGSSNTWL------------------GADKS--YVKTSTS 52 Query: 138 ------FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFD 191 + YGSGS SG DTV+ LG + + KQ G A++ G + D Sbjct: 53 SATSDKVSVTYGSGSFSGTEYTDTVT------LGSLTIPKQSIGVASRDSGFDGV----D 102 Query: 192 GILGMGYPFISVNKVLP--------VFDNLMKQKLVEKNIFSFYLNRDPT---GQPGGEL 240 GILG+G ++V + P V DNL Q + N+ + ++ +PT GEL Sbjct: 103 GILGVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLA--VSFEPTTSESSTNGEL 160 Query: 241 MLGGTDSRYYHGELSYLNVTR----KAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLL 296 G TDS Y G ++Y +T AYW ++ + GS ++ IVDTGT+L Sbjct: 161 TFGATDSSKYTGSITYTPITSTSPASAYWGINQ-SIRYGSSTSILS-STAGIVDTGTTLT 218 Query: 297 VGPVDEVKELQKAIGAVPLIQ-GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYI----L 351 + D + +KA GAV G + + ++L + F +GGQ +EL I L Sbjct: 219 LIASDAFAKYKKATGAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPRNL 278 Query: 352 KVS---QAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGF 401 + A + G +G D G +I G F+ +Y+V+D R+G Sbjct: 279 NTAIGGSASSVYLIVGDLGSD--SGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >3ZKX-A nrPDB Length = 386 Score = 110 bits (276), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 104/356 (29%), Positives = 166/356 (46%), Gaps = 46/356 (12%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ IGTPPQ ++ DTGSSN V +D +++++SSTY G Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDT------YFDTERSSTYRSKGFDV 71 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIF-GEATKQPGVVFIAAKFDGILGMG 197 + Y GS +G++ +D V++P + + IF E PG+ K++GILG+ Sbjct: 72 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGI-----KWNGILGLA 126 Query: 198 YPFIS--VNKVLPVFDNLMKQKLVEKNIFSFY-----LNRDPTGQPGGELMLGGTDSRYY 250 Y ++ + + FD+L+ Q + N+FS L +G GG L+LGG + Y Sbjct: 127 YATLAKPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLY 185 Query: 251 HGELSYLNVTRKAYWQVHMDQLEVGSE-LTL-CK--GGCEAIVDTGTSLLVGP---VDEV 303 G++ Y + + Y+Q+ + +LE+G + L L C+ +AIVD+GT+LL P D V Sbjct: 186 KGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAV 245 Query: 304 KELQKAIGAVPLIQGEY----MIPCEKVSS-----LPIITFKLGGQNYE------LHPEK 348 E +P + + C S P I+ L +N + P+ Sbjct: 246 VEAVARASLIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQL 305 Query: 349 YILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 YI + AG F I P + L ++G + +Y +FDR RVGFA + Sbjct: 306 YIQPMMGAGLNYECYRF---GISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFAAS 357 >2ASI-A nrPDB Length = 361 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 99/360 (27%), Positives = 168/360 (46%), Gaps = 53/360 (14%) Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 +Y + IGTP Q F ++FDTGSS+ WVP C + C ++ SST+ + Sbjct: 19 EYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSE-GCVGSRFFDPSASSTFKATNYN 77 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFG--------EATKQPGV-VFIAA 188 +I YG+G +G +D++++ G I V KQI A + P +F+ Sbjct: 78 LNITYGTGGANGLYFEDSIAI------GDITVTKQILAYVDNVRGPTAEQSPNADIFL-- 129 Query: 189 KFDGILGMGYPFISVNKVL------PVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELML 242 DG+ G YP + + V NL KQ L+ +FS Y+N T GE++ Sbjct: 130 --DGLFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMN---TNSGTGEVVF 184 Query: 243 GGTDSRYYHGELSYLNVTRK----AYWQVHMDQLEVGSELTLCKGGCEAI-VDTGTSLLV 297 GG ++ G+++Y +V + +W + + V + +A +DTGT+ + Sbjct: 185 GGVNNTLLGGDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFI 244 Query: 298 GPVDEVKELQKAIGAVP---LIQGEYMIPCEKV----SSLPIITFKLGGQNYELH----P 346 P ++ KA A+P Q +++PC S++ I+ K G + + Sbjct: 245 MPSSAASKIVKA--ALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIEISVPV 302 Query: 347 EKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 K +L V Q+ +T C+ F+ I P G +I+G++F+ + V+D NR+GFA A+ Sbjct: 303 SKMLLPVDQSNET-CM--FI---ILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFAPLAS 356 >3TPL-A nrPDB Length = 433 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 105/363 (28%), Positives = 169/363 (46%), Gaps = 54/363 (14%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 107 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI-AAKFDGILGMG 197 + Y G+ +G L D VS+P + + V I A + FI + ++GILG+ Sbjct: 108 YVPYTQGAWAGELGTDLVSIPHGPN---VTVRANI--AAITESDKFFINGSNWEGILGLA 162 Query: 198 YPFISV--NKVLPVFDNLMKQKLVEKNIFS-------FYLNRDPT-GQPGGELMLGGTDS 247 Y I+ + + P FD+L+KQ V N+FS F LN+ GG +++GG D Sbjct: 163 YAEIARPDDSLEPFFDSLVKQTHV-PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDH 221 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEV-GSELTL-CK--GGCEAIVDTGTSLLVGPVDEV 303 Y G L Y + R+ Y++V + ++E+ G +L + CK ++IVD+GT+ L P Sbjct: 222 SLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVF 281 Query: 304 KELQKAIGAVPLIQ--------GEYMIPCEKVSS-----LPIITFKLGG----QNYELH- 345 + K+I A + GE ++ C + + P+I+ L G Q++ + Sbjct: 282 EAAVKSIKAASSTEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITI 340 Query: 346 -PEKYILKVSQAGKTI--CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFA 402 P++Y+ V + C + S ++G V + +Y VFDR R+GFA Sbjct: 341 LPQQYLRPVEDVATSQDDCYKFAISQ-----SSTGTVMGAVIMEGFYVVFDRARKRIGFA 395 Query: 403 KAA 405 +A Sbjct: 396 VSA 398 >1MPP-A nrPDB Length = 361 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 97/356 (27%), Positives = 168/356 (47%), Gaps = 45/356 (12%) Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 +Y + IGTP Q F ++FDTGSS+ WVP C + C ++ SST+ + + Sbjct: 19 EYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSE-GCVGKRFFDPSSSSTFKETDYN 77 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAK-----FDG 192 +I YG+G +G +D+++V GG V++Q G + DG Sbjct: 78 LNITYGTGGANGIYFRDSITV------GGATVKQQTLAYVDNVSGPTAEQSPDSELFLDG 131 Query: 193 ILGMGYPFISV------NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 I G YP + + V NL KQ L+ +FS Y+N T GG+++ GG + Sbjct: 132 IFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMN---TNDGGGQVVFGGVN 188 Query: 247 SRYYHGELSYLNVTRKA----YWQVHMDQLEV-GSELTLCKGGCEAIVDTGTSLLVGPVD 301 + G++ Y +V + +W + +++ GS+ G +DTGT+ + P Sbjct: 189 NTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGSDAVSFDGAQAFTIDTGTNFFIAPSS 248 Query: 302 EVKELQKAIGAVPLI---QGEYMIPCEKV----SSLPIITFKLGGQNYELHP----EKYI 350 +++ KA A+P Q Y +PC K ++ ++ K G + + K + Sbjct: 249 FAEKVVKA--ALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPISKML 306 Query: 351 LKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 L V ++G+T C+ F+ + P G +I+G++F+ + V+D NR+GFA A+ Sbjct: 307 LPVDKSGET-CM--FI---VLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAPLAS 356 >3FV3-A nrPDB Length = 339 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 96/343 (27%), Positives = 149/343 (43%), Gaps = 47/343 (13%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKL-LDIACWVHHKYNSDKSSTYVKNGTS 137 Y ++ +G+ Q TV+ DTGSS+ WV + + + C + SS+Y G + Sbjct: 14 YASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGAA 73 Query: 138 FDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGM 196 F I YG GS S G +DTV++ G+ + Q + T+ + GILG+ Sbjct: 74 FTIRYGDGSTSQGTWGKDTVTI------NGVSITGQQIADVTQ-------TSVDQGILGI 120 Query: 197 GYPF------ISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 GY S + P +DN L KQ + N +S YLN P+ + G ++ GG D Sbjct: 121 GYTSNEAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNS-PSAET-GTIIFGGVD 178 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEV-GSELTLCKGGCEAIVDTGTSLLVGPVDEVKE 305 + Y G+L VT + + + + GS + G A++D+GT+L P D + Sbjct: 179 NAKYSGKLVAEQVTSSQALTISLASVNLKGSSFSFGDG---ALLDSGTTLTYFPSDFAAQ 235 Query: 306 LQKAIGA----VPLIQGEYMIPCEKVSSLPIITFKLG-GQNYELHPEKYILKVSQAGKTI 360 L GA V Q Y I C +S + F G G + +Y+ Q G Sbjct: 236 LADKAGARLVQVARDQYLYFIDCNTDTSGTTV-FNFGNGAKITVPNTEYVY---QNGDGT 291 Query: 361 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 CL G D ILGD F+ Y +++ + N + A+ Sbjct: 292 CLWGIQPSDDT-------ILGDNFLRHAYLLYNLDANTISIAQ 327 >2QZW-A nrPDB Length = 341 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 102/350 (29%), Positives = 157/350 (44%), Gaps = 60/350 (17%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVP--SIHC------KLLDIACWVHHKYNSDKSST 130 Y +I IG+ Q F V+ DTGSS+LWVP S+ C + D C Y S+T Sbjct: 14 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF-CKGKGIYTPKSSTT 72 Query: 131 YVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAK 189 GT F I YG GS S G L +DTV GG + KQ+F + TK + Sbjct: 73 SQNLGTPFYIGYGDGSSSQGTLYKDTVG------FGGASITKQVFADITK-------TSI 119 Query: 190 FDGILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 GILG+GY N+ +DN L Q ++ KN +S YLN P G+++ GG Sbjct: 120 PQGILGIGY---KTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAAT-GQIIFGGV 174 Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLE-VGSELTLCKGGCEAIVDTGTSLLVGPVDEVK 304 D Y G L + VT ++ ++ L+ VG + G + ++D+GT++ D + Sbjct: 175 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI---NGNIDVLLDSGTTITYLQQDVAQ 231 Query: 305 ELQKAIGAVPLIQGE----YMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 360 ++ A A G+ Y+ C+ ++ N++ + + + V + T Sbjct: 232 DIIDAFQAELKSDGQGHTFYVTDCQTSGTVDF--------NFDNNAK---ISVPASEFTA 280 Query: 361 CLSGFMGMDIPPPSGPLW-------ILGDVFIGCYYTVFDREYNRVGFAK 403 LS G P P L ILGD F+ Y V+D + +++ A+ Sbjct: 281 PLSYANGQ--PYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQ 328 >4Y9W-A nrPDB Length = 334 Score = 94.4 bits (233), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 96/344 (27%), Positives = 145/344 (42%), Gaps = 43/344 (12%) Query: 74 YLDAQYYG-EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYV 132 Y + YG + +G+ Q VV DTGSS+ WV C + ++ S+++ Sbjct: 8 YFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFK 67 Query: 133 KNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFD 191 G+SF I YG S S G QDT+ LGG + Q F + T + Sbjct: 68 SLGSSFSIGYGDKSSSIGTWGQDTIY------LGGTSITNQRFADVTS-------TSVNQ 114 Query: 192 GILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDS 247 GILG+G + P +DN L KQ ++ N +S YLN G G ++ GG D+ Sbjct: 115 GILGVGR--VETESANPPYDNVPITLKKQGKIKTNAYSLYLNS--PGAATGTIIFGGVDN 170 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 Y G+L + Y V++ L + + G +VD+GT++ P V +L Sbjct: 171 AKYSGKLIEEPLVSDRYLAVNLKSLNYNGDNS--NAGFGVVVDSGTTISYLPDSIVDDLA 228 Query: 308 KAIGA----VPLIQGEYMIPCE-KVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 +GA V L Y I C TF G + + +++L Q+ C+ Sbjct: 229 NKVGAYLEPVGLGNELYFIDCNANPQGSASFTFDNGAK-ITVPLSEFVL---QSTANACV 284 Query: 363 SGFMGMD---IPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 G D +PP ILGD F+ Y VF+ + V A+ Sbjct: 285 WGLQSSDRQNVPP------ILGDNFLRHAYVVFNLDKETVSLAQ 322 >1J71-A nrPDB Length = 334 Score = 92.0 bits (227), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 91/338 (26%), Positives = 147/338 (43%), Gaps = 42/338 (12%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWV--PSIHCKL-----LDIACWVHHKYNSDKSSTY 131 Y +I +G+ Q TVV DTGSS+LWV C++ + C ++ SS+ Sbjct: 14 YAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQEGTFDPSSSSSA 73 Query: 132 VKNGTSFDIHYGS-GSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 F I YG S G +DTV GGI ++ Q F + T + Sbjct: 74 QNLNQDFSIEYGDLTSSQGSFYKDTVG------FGGISIKNQQFADVTT-------TSVD 120 Query: 191 DGILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 GI+G+G F + ++DN L KQ ++ KN +S YLN + G+++ GG D Sbjct: 121 QGIMGIG--FTADEAGYNLYDNVPVTLKKQGIINKNAYSLYLNSEDAST--GKIIFGGVD 176 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 + Y G L+ L VT +VH+ + + T + ++D+GT++ + Sbjct: 177 NAKYTGTLTALPVTSSVELRVHLGSINF--DGTSVSTNADVVLDSGTTITYFSQSTADKF 234 Query: 307 QKAIGAVPLIQGE-YMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + +GA + E Y +P +S + F G + + + ILK S + +IC G Sbjct: 235 ARIVGATWDSRNEIYRLPSCDLSGDAVFNFDQGVK-ITVPLSELILKDSDS--SICYFGI 291 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 D ILGD F+ Y V+D + + A+ Sbjct: 292 SRNDAN-------ILGDNFLRRAYIVYDLDDKTISLAQ 322 >3PVK-A nrPDB Length = 342 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 96/350 (27%), Positives = 147/350 (42%), Gaps = 59/350 (16%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIH--CKLL---DIACWVHHK--YNSDKSSTY 131 Y +I +G+ Q V+ DTGSS+LWVP ++ C++ A + K Y+ SS Sbjct: 14 YAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSAS 73 Query: 132 VKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 T F I YG GS S G L +DTV GG+ ++ Q+ + V + Sbjct: 74 QDLNTPFKIGYGDGSSSQGTLYKDTVG------FGGVSIKNQVLAD-------VDSTSID 120 Query: 191 DGILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 GILG+GY N+ +DN L KQ ++ KN +S YLN G+++ GG D Sbjct: 121 QGILGVGYK---TNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAAT--GQIIFGGVD 175 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 + Y G L L VT ++ + +EV + T+ + ++D+GT++ D ++ Sbjct: 176 NAKYSGSLIALPVTSDRELRISLGSVEVSGK-TINTDNVDVLLDSGTTITYLQQDLADQI 234 Query: 307 QKAIGAVPLIQGE-----YMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTIC 361 KA L Q Y + C +S + F K+S Sbjct: 235 IKAFNG-KLTQDSNGNSFYEVDC-NLSGDVVFNFSKNA------------KISVPASEFA 280 Query: 362 LSGFMGMDIPP--------PSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 S G D P ILGD F+ Y V+D + N + A+ Sbjct: 281 AS-LQGDDGQPYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLAQ 329 >4B1C-A nrPDB Length = 375 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 101/355 (28%), Positives = 163/355 (45%), Gaps = 52/355 (14%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 73 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI-AAKFDGILGMG 197 + Y G G L D VS+P + + V I A + FI + ++GILG+ Sbjct: 74 YVPYTQGKWEGELGTDLVSIPHGPN---VTVRANI--AAITESDKFFINGSNWEGILGLA 128 Query: 198 YPFISV--NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELS 255 Y I+ + + P FD+L+KQ V N+FS L + +++GG D Y G L Sbjct: 129 YAEIARPDDSLEPFFDSLVKQTHV-PNLFSLQLCGGGS------MIIGGIDHSLYTGSLW 181 Query: 256 YLNVTRKAYWQVHMDQLEV-GSELTL-CK--GGCEAIVDTGTSLLVGPVDEVKELQKAIG 311 Y + R+ Y++V + ++E+ G +L + CK ++IVD+GT+ L P + K+I Sbjct: 182 YTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK 241 Query: 312 AVPLIQ--------GEYMIPCEKVSS-----LPIITFKLGG----QNYELH--PEKYILK 352 A + GE ++ C + + P+I+ L G Q++ + P++Y+ Sbjct: 242 AASSTEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRP 300 Query: 353 VSQAGKTI--CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 V + C + S ++G V + +Y VFDR R+GFA +A Sbjct: 301 VEDVATSQDDCYKFAISQ-----SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 350 >1B5F-B nrPDB Length = 87 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 44/87 (50%), Positives = 58/87 (66%), Gaps = 1/87 (1%) Query: 319 EYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLW 378 E + C +SS+P ++F +GG+ + L PE+YILKV + T C+SGF MD GPLW Sbjct: 2 ELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPLW 60 Query: 379 ILGDVFIGCYYTVFDREYNRVGFAKAA 405 ILGDVF+ Y+TVFD VGFA+AA Sbjct: 61 ILGDVFMRPYHTVFDYGNLLVGFAEAA 87 >1IBQ-A nrPDB Length = 325 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 103/323 (31%), Positives = 147/323 (45%), Gaps = 41/323 (12%) Query: 96 FDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGS-LSGYLSQD 154 FDTGS++LWV S L + H + SS +G S+DI YG GS SG + +D Sbjct: 31 FDTGSADLWVFSDE---LPSSEQTGHDLYTPSSSATKLSGYSWDISYGDGSSASGDVYRD 87 Query: 155 TVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLP-----V 209 TV+V GG+ KQ A+K DG+LG+ F S+N V P Sbjct: 88 TVTV------GGVTTNKQAVEAASKISSEFVQDTANDGLLGLA--FSSINTVQPKAQTTF 139 Query: 210 FDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNV-TRKAYWQVH 268 FD + Q ++ +F+ L D G G D Y G ++Y + + + YW Sbjct: 140 FDTVKSQ--LDSPLFAVQLKHDAPGV----YDFGYIDDSKYTGSITYTDADSSQGYWGFS 193 Query: 269 MDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL--QKAIGAVPLIQ-GEYMIPCE 325 D +G + G AI DTGT+L++ DE+ ++ GA + G Y+ C Sbjct: 194 TDGYSIGDGSSSSSG-FSAIADTGTTLILLD-DEIVSAYYEQVSGAQESYEAGGYVFSCS 251 Query: 326 KVSSLPIITFKLGGQNYE-LHPEKYILKVS-QAGKTICLSGFMGMDIPPPSG-PLWILGD 382 + LP T +G +Y+ + P KYI G + C G I SG L ILGD Sbjct: 252 --TDLPDFTVVIG--DYKAVVPGKYINYAPVSTGSSTCYGG-----IQSNSGLGLSILGD 302 Query: 383 VFIGCYYTVFDREYNRVGFAKAA 405 VF+ Y VF+ E ++GFA A Sbjct: 303 VFLKSQYVVFNSEGPKLGFAAQA 325 >2H6T-A nrPDB Length = 340 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 113/240 (47%), Gaps = 36/240 (15%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPS--IHCKLLDIA----CWVHHKYNSDKSSTYV 132 Y +I +G+ Q TVV DTGSS+LWVP + C+ C Y+ SS+ Sbjct: 14 YASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQ 73 Query: 133 KNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFD 191 + F I YG G+ S G +DT+ GGI + KQ F + T + Sbjct: 74 NLNSPFSIEYGDGTTSQGTWYKDTIG------FGGISITKQQFADVTS-------TSVDQ 120 Query: 192 GILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLN-RDPTGQPGGELMLGGTD 246 GILG+GY ++ +DN L Q ++ KN +S YLN R T G+++ GG D Sbjct: 121 GILGIGYK---THEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQAT---SGQIIFGGVD 174 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTS---LLVGPVDEV 303 + Y G L L VT ++H++ ++V + + ++D+GT+ L G D+V Sbjct: 175 NAKYSGTLIALPVTSDNELRIHLNTVKVAGQ--SINADVDVLLDSGTTITYLQQGVADQV 232 >1IZE-A nrPDB Length = 323 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 104/341 (30%), Positives = 148/341 (43%), Gaps = 42/341 (12%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNG 135 D +Y ++ +G + FDTGS++LWV S + + H Y + SS +G Sbjct: 14 DEEYITQVTVG--DDTLGLDFDTGSADLWVFSSQTPSSERSG---HDYYTPGSSAQKIDG 68 Query: 136 TSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 ++ I YG GS SG + +D V+V GG+ + Q A K DG+L Sbjct: 69 ATWSISYGDGSSASGDVYKDKVTV------GGVSYDSQAVESAEKVSSEFTQDTANDGLL 122 Query: 195 GMGYPFISVNKVLPV-----FDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRY 249 G+ F S+N V P FDN+ K L E IF+ L + G G TDS Sbjct: 123 GL--AFSSINTVQPTPQKTFFDNV-KSSLSEP-IFAVALKHNAPGV----YDFGYTDSSK 174 Query: 250 YHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLV---GPVDEVKE 305 Y G ++Y +V + +W D +GS+ + I DTGT+LL+ VD E Sbjct: 175 YTGSITYTDVDNSQGFWGFTADGYSIGSDSSSDS--ITGIADTGTTLLLLDDSIVDAYYE 232 Query: 306 LQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 Q + QG Y+ P +SLP + +G + P +YI + G G Sbjct: 233 -QVNGASYDSSQGGYVFPSS--ASLPDFSVTIGDYTATV-PGEYI-SFADVGNGQTFGG- 286 Query: 366 MGMDIPPPSG-PLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 I SG I GDVF+ Y VFD R+GFA A Sbjct: 287 ----IQSNSGIGFSIFGDVFLKSQYVVFDASGPRLGFAAQA 323 >2QZX-A nrPDB Length = 342 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 93/362 (25%), Positives = 145/362 (40%), Gaps = 60/362 (16%) Query: 66 PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHK--- 122 PV+ L N Y +I +G+ Q V+ DTGSS+LW+P ++ I W K Sbjct: 2 PVAVTLHNEA-ITYTADITVGSDNQKLNVIVDTGSSDLWIP--DSNVICIPKWRGDKGDF 58 Query: 123 ------YNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFG 175 Y+ S T T FDI YG GS + G L +DTV + GG+ V Q+F Sbjct: 59 CKSAGSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGI------GGVSVRDQLFA 112 Query: 176 EATKQPGVVFIAAKFDGILGMGYPFISVNKV----LPVFDNLMKQKLVEKNIFSFYLNRD 231 V+ + GILG+G+ + LP+ +L Q ++ K +S YLN Sbjct: 113 N-------VWSTSARKGILGIGFQSGEATEFDYDNLPI--SLRNQGIIGKAAYSLYLNSA 163 Query: 232 PTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDT 291 G+++ GG D Y G L L +T + V + + V ++D+ Sbjct: 164 EAST--GQIIFGGIDKAKYSGSLVDLPITSEKKLTVGLRSVNVRGR--NVDANTNVLLDS 219 Query: 292 GTSLLVGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVSSLPIITFKLGGQNYELHPE 347 GT++ V+ + AIGA Y+ C+ + I F+ G Sbjct: 220 GTTISYFTRSIVRNILYAIGAQMKFDSAGNKVYVADCKTSGT---IDFQFGNN------- 269 Query: 348 KYILKVSQAGKTICLSGFMGMDIPPPSGPLW-------ILGDVFIGCYYTVFDREYNRVG 400 LK+S + P P + ILGD F+ Y V++ + ++ Sbjct: 270 ---LKISVPVSEFLFQTYYTSGKPFPKCEVRIRESEDNILGDNFLRSAYVVYNLDDKKIS 326 Query: 401 FA 402 A Sbjct: 327 MA 328 >5HCT-A nrPDB Length = 419 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 105/402 (26%), Positives = 159/402 (39%), Gaps = 50/402 (12%) Query: 22 IRIPLRKFT---SIRRTMTEVG----GSVEDLILKGPITKYSMQSSPRTKEPVSELLKNY 74 +R P KF S+++T + G +ED + + T P+ + Sbjct: 47 VRNPNYKFNGPLSVKKTYLKYGVPIPAWLEDAVQNSTSGLAERSTGSATTTPI-----DS 101 Query: 75 LDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKN 134 LD Y + IGTP Q + FDTGSS+LWV S ++ + + ++ + Sbjct: 102 LDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSG 161 Query: 135 GTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 T + S SG + DTVSV GG+ V Q A K + DG+L Sbjct: 162 ATWSISYGDGSSSSGDVYTDTVSV------GGLTVTGQAVESAKKVSSSFTEDSTIDGLL 215 Query: 195 GMGYPFISVNKVLPV-----FDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRY 249 G+ F ++N V P FDN + ++ +F+ L G G D+ Sbjct: 216 GLA--FSTLNTVSPTQQKTFFDN--AKASLDSPVFTADLGY----HAPGTYNFGFIDTTA 267 Query: 250 YHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 Y G ++Y V T++ +W+ VGS T + I DTGT+LL P V Sbjct: 268 YTGSITYTAVSTKQGFWEWTSTGYAVGSG-TFKSTSIDGIADTGTTLLYLPATVVSAYWA 326 Query: 309 AIGAVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYI-LKVSQAGKTICLSGF 365 + G Y+ PC ++LP TF +G + P YI G + C G Sbjct: 327 QVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVI-PGDYIDFGPISTGSSSCFGGI 383 Query: 366 M---GMDIPPPSGPLWILGDVFIGCYYTVFDREYN-RVGFAK 403 G+ I I GDV + + VF+ +GFA Sbjct: 384 QSSAGIGIN-------IFGDVALKAAFVVFNGATTPTLGFAS 418 >1PPK-E nrPDB Length = 323 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 95/325 (29%), Positives = 140/325 (43%), Gaps = 48/325 (14%) Query: 96 FDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGS-LSGYLSQD 154 FDTGS++LWV S + H YN + + G ++ I YG GS SG + D Sbjct: 32 FDTGSADLWVFSTELPASQQSG--HSVYNPSATGKELS-GYTWSISYGDGSSASGNVFTD 88 Query: 155 TVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF------DGILGMGYPFISVNKVLP 208 +V+V GG+ Q +A +Q I+A+F DG+LG+ F S+N V P Sbjct: 89 SVTV------GGVTAHGQAV-QAAQQ-----ISAQFQQDTNNDGLLGL--AFSSINTVQP 134 Query: 209 ----VFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNV-TRKA 263 F + +K L + +F+ L QPG G DS Y G L+Y V + Sbjct: 135 QSQTTFFDTVKSSLAQP-LFAVALKHQ---QPG-VYDFGFIDSSKYTGSLTYTGVDNSQG 189 Query: 264 YWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQ--GEYM 321 +W ++D GS+ G I DTGT+LL+ V + + G Y+ Sbjct: 190 FWSFNVDSYTAGSQ---SGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYV 246 Query: 322 IPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSG-PLWIL 380 C ++LP + + G + P I + CL G I SG I Sbjct: 247 FDCS--TNLPDFSVSISGYTATV-PGSLINYGPSGDGSTCLGG-----IQSNSGIGFSIF 298 Query: 381 GDVFIGCYYTVFDREYNRVGFAKAA 405 GD+F+ Y VFD + ++GFA A Sbjct: 299 GDIFLKSQYVVFDSDGPQLGFAPQA 323 >3PI0-A nrPDB Length = 330 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 94/342 (27%), Positives = 138/342 (40%), Gaps = 38/342 (11%) Query: 75 LDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKN 134 LD Y + IGTP Q + FDTGSS+LWV S ++ + + ++ + Sbjct: 13 LDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSG 72 Query: 135 GTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 T + S SG + DTVSV GG+ V Q A K + DG+L Sbjct: 73 ATWSISYGDGSSSSGDVYTDTVSV------GGLTVTGQAVESAKKVSSSFTEDSTIDGLL 126 Query: 195 GMGYPFISVNKVLPV-----FDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRY 249 G+ F ++N V P FDN + ++ +F+ L G G D+ Sbjct: 127 GLA--FSTLNTVSPTQQKTFFDN--AKASLDSPVFTADLGY----HAPGTYNFGFIDTTA 178 Query: 250 YHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 Y G ++Y V T++ +W+ VGS T + I DTGT+LL P V Sbjct: 179 YTGSITYTAVSTKQGFWEWTSTGYAVGSG-TFKSTSIDGIADTGTTLLYLPATVVSAYWA 237 Query: 309 AIGAVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYI-LKVSQAGKTICLSGF 365 + G Y+ PC ++LP TF +G + P YI G + C G Sbjct: 238 QVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVI-PGDYIDFGPISTGSSSCFGGI 294 Query: 366 M---GMDIPPPSGPLWILGDVFIGCYYTVFDREYN-RVGFAK 403 G+ I I GDV + + VF+ +GFA Sbjct: 295 QSSAGIGIN-------IFGDVALKAAFVVFNGATTPTLGFAS 329 >4ZL4-A nrPDB Length = 444 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 73/286 (25%), Positives = 116/286 (40%), Gaps = 70/286 (24%) Query: 77 AQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH--HKYNSDKSSTY--- 131 A Y+ +I IGTP Q +++ DTGSS+L P CK C VH + +N + S T Sbjct: 28 AYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCK----NCGVHMENPFNLNNSKTSSIL 83 Query: 132 -------------VKNGTSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 VK + Y GS +SG+ D VSV +V + Sbjct: 84 YCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSV---VSYNNERVTFRKLMGC 140 Query: 178 TKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVE-KNIFSFYLNRDPTGQP 236 +F+ + G+LGM +S + +P F NL+ + K +F+ ++ + Sbjct: 141 HMHEESLFLYQQATGVLGMS---LSKPQGIPTFVNLLFDNAPQLKQVFTICISEN----- 192 Query: 237 GGELMLGGTDSRYY-----------------------HGE-----------LSYLNVTRK 262 GGEL+ GG D Y GE + + NVTRK Sbjct: 193 GGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKVVWENVTRK 252 Query: 263 AYWQVHMDQLEV-GSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 Y+ + + L++ G+ + G E +VD+G++ P D +L Sbjct: 253 YYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLN 298 >3EMY-A nrPDB Length = 329 Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 83/337 (24%), Positives = 130/337 (38%), Gaps = 31/337 (9%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNG 135 D++Y + IGTP Q + FDTGSS+LWV S + + +S V Sbjct: 14 DSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPKSSATGHAIYTPSKSSTSKKVSGA 73 Query: 136 TSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILG 195 + + S SG + D V++ GG V Q AT+ G++G Sbjct: 74 SWSISYGDGSSSSGDVYTDKVTI------GGFSVNTQGVESATRVSTEFVQDTVISGLVG 127 Query: 196 MGYPFISVNKVLP-----VFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYY 250 + F S N+V P F N L E +F+ L GQ G G D+ Sbjct: 128 LA--FDSGNQVRPHPQKTWFSN-AASSLAEP-LFTADLRH---GQ-NGSYNFGYIDTSVA 179 Query: 251 HGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKA 309 G ++Y V + +W+ VG L + + I DTGT+LL+ + V Sbjct: 180 KGPVAYTPVDNSQGFWEFTASGYSVGGG-KLNRNSIDGIADTGTTLLLLDDNVVDAYYAN 238 Query: 310 IGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM--- 366 + + + + + LP +F +G + + L + G + C G Sbjct: 239 VQSAQYDNQQEGVVFDCDEDLPSFSFGVGSSTITIPGDLLNLTPLEEGSSTCFGGLQSSS 298 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 G+ I I GDV + VFD R+G+A+ Sbjct: 299 GIGIN-------IFGDVALKAALVVFDLGNERLGWAQ 328 >6CT6-A nrPDB Length = 338 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 65/134 (48%), Gaps = 24/134 (17%) Query: 200 FISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELM-LGGTDSRYYH------- 251 +I++N + P+ + + K + +++I + Y + T Q GG+++ L G S YY Sbjct: 197 YITINGI-PIQEFINKGLINKEDINNIY---NKTKQAGGDIVRLLGQGSAYYAPGTSAIL 252 Query: 252 GELSYLNVTRKAYW-------QVHMDQLEVGSELTLCKGGCEAIVDTGTS-----LLVGP 299 SYL ++ + Q +++ +G + G E I++ + LL G Sbjct: 253 MAESYLKDKKRLFVSSCYLNGQYNVNNHYLGVPCIIGGKGIEQIIELDLNQEEKKLLQGS 312 Query: 300 VDEVKELQKAIGAV 313 +DEV E+QKAI A+ Sbjct: 313 IDEVLEMQKAIAAL 326 >4QAQ-A nrPDB Length = 201 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%) Query: 323 PCEKVSSLPIITFKLGGQN-YELHPEKYILKVSQAGKTICLSGFMGMDIPPPSG-PLWI 379 P E +L + F L +N Y H E +L V KT G + PPPSG LWI Sbjct: 16 PAEAARTLSLFPFSLNKENFYTYHTENVLLDV-MVLKTWGYRGVVQALSPPPSGYDLWI 73 >4KQP-A nrPDB Length = 232 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 41 GSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGS 100 GS+ L+ P+ KY+++ + P+ + D QY + G+ P+ +F+ G Sbjct: 157 GSINALMDDEPVIKYAIKQGQKFATPIKPI----PDGQYGFAVKKGSNPELIE-MFNNGL 211 Query: 101 SNLWVPSIHCKLLD 114 +NL + K++D Sbjct: 212 ANLRANGEYDKIID 225 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5UX4-A nrPDB 582 e-166 5MKT-A nrPDB 461 e-130 4AMT-A nrPDB 460 e-130 5MLG-A nrPDB 457 e-129 5NFG-A nrPDB 437 e-123 2PSG-A nrPDB 429 e-120 1TZS-A nrPDB 427 e-120 1SMR-A nrPDB 414 e-116 3VCM-A nrPDB 409 e-114 5N71-A nrPDB 405 e-113 1PSO-E nrPDB 397 e-111 4PEP-A nrPDB 394 e-110 4AA9-A nrPDB 394 e-110 4CMS-A nrPDB 386 e-107 1AM5-A nrPDB 384 e-107 1FMX-A nrPDB 373 e-104 1AVF-A nrPDB 364 e-101 1MIQ-A nrPDB 347 4e-96 2BJU-A nrPDB 346 1e-95 2ANL-A nrPDB 346 1e-95 5BWY-A nrPDB 342 2e-94 4OC6-B nrPDB 342 2e-94 1QS8-A nrPDB 341 3e-94 3QS1-A nrPDB 338 3e-93 1XDH-A nrPDB 338 3e-93 5JOD-A nrPDB 337 4e-93 5I70-B nrPDB 335 2e-92 1QDM-A nrPDB 321 4e-88 3QVI-A nrPDB 312 1e-85 3FNT-A nrPDB 306 8e-84 1B5F-A nrPDB 284 5e-77 3LIZ-A nrPDB 276 9e-75 1UH8-A nrPDB 257 6e-69 5HCT-A nrPDB 253 1e-67 2ASI-A nrPDB 252 2e-67 2QZW-A nrPDB 249 2e-66 4Y9W-A nrPDB 245 3e-65 3TPL-A nrPDB 244 4e-65 3PVK-A nrPDB 244 6e-65 2QZX-A nrPDB 243 8e-65 3ZKX-A nrPDB 243 9e-65 3FV3-A nrPDB 241 5e-64 1J71-A nrPDB 240 9e-64 1MPP-A nrPDB 237 6e-63 2H6T-A nrPDB 230 8e-61 4B1C-A nrPDB 228 5e-60 3PI0-A nrPDB 219 2e-57 1IBQ-A nrPDB 218 4e-57 1PPK-E nrPDB 216 1e-56 3EMY-A nrPDB 214 5e-56 3OAD-B nrPDB 212 3e-55 1IZE-A nrPDB 210 7e-55 3O9L-A nrPDB 205 3e-53 1WKR-A nrPDB 192 3e-49 4ZL4-A nrPDB 172 2e-43 4OD9-A nrPDB 157 6e-39 1B5F-B nrPDB 112 3e-25 Sequences not found previously or not previously below threshold: 3AUP-A nrPDB 56 2e-08 4PPH-A nrPDB 54 9e-08 1T6G-A nrPDB 40 0.002 3HD8-A nrPDB 37 0.020 4Y8P-I nrPDB 36 0.036 3Q31-A nrPDB 34 0.11 2BKL-A nrPDB 33 0.25 3OS6-A nrPDB 31 1.1 5GJQ-a nrPDB 30 2.1 5LEZ-N nrPDB 30 2.1 3VLB-A nrPDB 30 2.8 2D81-A nrPDB 29 3.8 1IGA-A nrPDB 28 6.5 >5UX4-A nrPDB Length = 420 Score = 582 bits (1500), Expect = e-166, Method: Composition-based stats. Identities = 391/407 (96%), Positives = 393/407 (96%), Gaps = 1/407 (0%) Query: 1 MQTPGVLLLILGLLDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS 60 M+ V L L + S LIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS Sbjct: 1 MEWSWVFLFFLSVTTGVHS-LIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS 59 Query: 61 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 120 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH Sbjct: 60 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 119 Query: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 180 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ Sbjct: 120 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 179 Query: 181 PGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 240 PGVVFIAAKFDGILGMGYPFISVN VLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL Sbjct: 180 PGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 239 Query: 241 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV 300 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV Sbjct: 240 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV 299 Query: 301 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 360 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI Sbjct: 300 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 359 Query: 361 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL Sbjct: 360 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 406 >5MKT-A nrPDB Length = 389 Score = 461 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 171/391 (43%), Positives = 242/391 (61%), Gaps = 11/391 (2%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKN 73 L ++ RIPL+K S+R + E G + L + + T +L N Sbjct: 1 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAE---WGVFTKRPSLTNLTSPVVLTN 57 Query: 74 YLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVK 133 YL+ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC +H Y S SS+Y++ Sbjct: 58 YLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYME 117 Query: 134 NGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193 NG+ F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ P + F+ AKFDG+ Sbjct: 118 NGSDFTIHYGSGRVKGFLSQDSVTV------GGITVT-QTFGEVTELPLIPFMLAKFDGV 170 Query: 194 LGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGE 253 LGMG+P +V V PVFD+++ Q ++++ +FS Y NR + GGE++LGG+D ++Y G Sbjct: 171 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQGN 229 Query: 254 LSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAV 313 Y+++++ WQ+ M + VGS LC+ GC +VDTG+S + P +K + +A+GA Sbjct: 230 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 289 Query: 314 PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPP 373 EY++ C +V +LP I+F LGG+ Y L Y+L+ +C MDIPPP Sbjct: 290 EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 349 Query: 374 SGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +GP+W+LG FI +YT FDR NR+GFA A Sbjct: 350 TGPVWVLGATFIRKFYTEFDRHNNRIGFALA 380 >4AMT-A nrPDB Length = 383 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 166/393 (42%), Positives = 242/393 (61%), Gaps = 13/393 (3%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKN 73 L ++ RI L++ SIR ++ E G D+ GP M+ S +L N Sbjct: 1 LPTDTTTFKRIFLKRMPSIRESLKERGV---DMARLGPEWSQPMKRLTLGNTTSSVILTN 57 Query: 74 YLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVK 133 Y+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC H +++ SS+Y Sbjct: 58 YMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKH 117 Query: 134 NGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193 NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ P + F+ A+FDG+ Sbjct: 118 NGTELTLRYSTGTVSGFLSQDIITV------GGITVT-QMFGEVTEMPALPFMLAEFDGV 170 Query: 194 LGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQP--GGELMLGGTDSRYYH 251 +GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD GG+++LGG+D ++Y Sbjct: 171 VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYE 230 Query: 252 GELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIG 311 G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S + G +++L +A+G Sbjct: 231 GNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALG 290 Query: 312 AVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIP 371 A + +Y++ C + +LP I+F LGG+ Y L Y+ + S + K +C MDIP Sbjct: 291 AKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIP 349 Query: 372 PPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 PP+GP W LG FI +YT FDR NR+GFA A Sbjct: 350 PPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 382 >5MLG-A nrPDB Length = 389 Score = 457 bits (1175), Expect = e-129, Method: Composition-based stats. Identities = 169/391 (43%), Positives = 248/391 (63%), Gaps = 11/391 (2%) Query: 14 LDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKN 73 L +++ RI L+K S+R + E G + + + ++ S T +L N Sbjct: 1 LPTDTASFGRILLKKMPSVREILEERGVDMTRISAE---WGEFIKKSSFTNVTSPVVLTN 57 Query: 74 YLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVK 133 YLD QYYGEIGIGTP Q F V+FDTGS+NLWVPS C L AC +H+ Y+S +SS+Y++ Sbjct: 58 YLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYME 117 Query: 134 NGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193 NGT F IHYGSG + G+LSQD V+V GGI V Q FGE T+ P + F+ AKFDG+ Sbjct: 118 NGTEFTIHYGSGKVKGFLSQDVVTV------GGIIVT-QTFGEVTELPLIPFMLAKFDGV 170 Query: 194 LGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGE 253 LGMG+P +V+ V+PVFD+++ Q+++++ +FS Y +R+ + GGE++LGG+D ++Y G Sbjct: 171 LGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRE-SHLLGGEVVLGGSDPQHYQGN 229 Query: 254 LSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAV 313 Y+++++ WQ+ M + VG LC+ GC A+VDTGTS + GP ++ + +A+G Sbjct: 230 FHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVK 289 Query: 314 PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPP 373 Y++ C +V +LP I+F LGG+ Y L Y+ K +C+ G+DIPPP Sbjct: 290 EKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPP 349 Query: 374 SGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +GP+W+LG FI +YT FDR NR+GFA A Sbjct: 350 TGPVWVLGATFIRKFYTEFDRHNNRIGFALA 380 >5NFG-A nrPDB Length = 383 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 168/390 (43%), Positives = 236/390 (60%), Gaps = 12/390 (3%) Query: 17 SSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLD 76 S+ L+R+ L+K R G +L + + + R L N D Sbjct: 3 SNGGLLRVGLKKRKVDRLDQLRAHGV---HMLGNARKDFGFRRTLRDSGSGIVALTNDRD 59 Query: 77 AQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGT 136 YYGEIGIGTPPQ F V+FDTGSS+LWVPS C +AC +H +Y+S SSTY NGT Sbjct: 60 TAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKCDT-SLACVIHPRYDSGDSSTYKGNGT 118 Query: 137 SFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGM 196 + I YG+G++ G+ SQD+V V G + VE Q F E T++ VF+ ++FDGILG+ Sbjct: 119 TASIQYGTGAIVGFYSQDSVEV------GDLVVEHQDFIETTEEDDTVFLKSEFDGILGL 172 Query: 197 GYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSY 256 G+ IS K +PV+ N++ Q LVE+ +FSF+LNR+ + GGEL+ GG D ++ G +Y Sbjct: 173 GFQEISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTY 232 Query: 257 LNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAV-P 314 + VTRK YWQ M + +G + + C GGC AI D+GTS GP + ++ +AIGA Sbjct: 233 VPVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGG 292 Query: 315 LIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPS 374 E ++ C +SS+P I F +G + +E+ PE+YI KV + C+SGF +DI P Sbjct: 293 GGSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQ 352 Query: 375 GPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 GP+WILGD+F+G Y+TVFD RVGFA+A Sbjct: 353 GPIWILGDMFMGPYHTVFDYGKLRVGFAEA 382 >2PSG-A nrPDB Length = 370 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 177/388 (45%), Positives = 236/388 (60%), Gaps = 21/388 (5%) Query: 21 LIRIPLRKFTSIRRTMTEVGGSVEDLIL---KGPITKYSMQSSPRTKEPVSELLKNYLDA 77 L+++PL + S+R+ + + G ++D + P +KY +++ + E L+NYLD Sbjct: 1 LVKVPLVRKKSLRQNLIK-DGKLKDFLKTHKHNPASKYFPEAAALIGD---EPLENYLDT 56 Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 +Y+G IGIGTP Q FTV+FDTGSSNLWVPS++C L AC H+++N D SST+ Sbjct: 57 EYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDSSTFEATSQE 114 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMG 197 I YG+GS++G L DTV V GGI QIFG + +PG A FDGILG+ Sbjct: 115 LSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYAPFDGILGLA 168 Query: 198 YPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYL 257 YP IS + PVFDNL Q LV +++FS YL+ + G ++LGG DS YY G L+++ Sbjct: 169 YPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDS--GSVVLLGGIDSSYYTGSLNWV 226 Query: 258 NVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQ 317 V+ + YWQ+ +D + + E C GGC+AIVDTGTSLL GP + +Q IGA Sbjct: 227 PVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSD 286 Query: 318 GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPL 377 GE +I C + SLP I F + G Y L P YIL+ + C SGF GMD+P SG L Sbjct: 287 GEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDS----CTSGFEGMDVPTSSGEL 342 Query: 378 WILGDVFIGCYYTVFDREYNRVGFAKAA 405 WILGDVFI YYTVFDR N+VG A A Sbjct: 343 WILGDVFIRQYYTVFDRANNKVGLAPVA 370 >1TZS-A nrPDB Length = 351 Score = 427 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 172/341 (50%), Positives = 228/341 (66%), Gaps = 9/341 (2%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 + E L NYLD +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H ++ Sbjct: 10 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRF 67 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV 183 +SSTY + G SF I YG+GSLSG + D VSV G+ V Q FGE+ +PG Sbjct: 68 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVE------GLTVVGQQFGESVTEPGQ 121 Query: 184 VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLG 243 F+ A+FDGILG+GYP ++V V PVFDN+M Q LV+ +FS Y++ +P G G EL+ G Sbjct: 122 TFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFG 181 Query: 244 GTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEV 303 G D ++ G L+++ VT++AYWQ+ +D ++VG + C GC+AIVDTGTSL+ GP D++ Sbjct: 182 GYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI 241 Query: 304 KELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLS 363 K+LQ AIGA P+ GEY + C ++ +P +TF + G Y L P Y L G C S Sbjct: 242 KQLQNAIGAAPV-DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 300 Query: 364 GFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 GF G+DI PP+GPLWILGDVFI +Y+VFDR NRVG A A Sbjct: 301 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 341 >1SMR-A nrPDB Length = 335 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 160/337 (47%), Positives = 224/337 (66%), Gaps = 8/337 (2%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 +L NYL++QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC +H Y S Sbjct: 6 PVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSD 65 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIA 187 SS+Y++NG F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ P + F+ Sbjct: 66 SSSYMENGDDFTIHYGSGRVKGFLSQDSVTV------GGITVT-QTFGEVTQLPLIPFML 118 Query: 188 AKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDS 247 A+FDG+LGMG+P +V V PVFD+++ Q ++++ +FS Y NR P GGE++LGG+D Sbjct: 119 AQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGP-HLLGGEVVLGGSDP 177 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 ++Y G+ Y+++++ WQ+ M + VGS LC+ GCE +VDTG+S + P +K + Sbjct: 178 QHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIM 237 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 +A+GA EY++ C +V +LP I+F LGG+ Y L Y+L+ +C Sbjct: 238 QALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHA 297 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 MDIPPP+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 298 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 334 >3VCM-A nrPDB Length = 335 Score = 409 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 153/345 (44%), Positives = 221/345 (64%), Gaps = 11/345 (3%) Query: 60 SPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWV 119 S +L NY+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC Sbjct: 1 LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVY 60 Query: 120 HHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATK 179 H +++ SS+Y NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ Sbjct: 61 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITV------GGITVT-QMFGEVTE 113 Query: 180 QPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGE 239 P + F+ A+FDG++GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD GG+ Sbjct: 114 MPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD---SLGGQ 170 Query: 240 LMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGP 299 ++LGG+D ++Y G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S + G Sbjct: 171 IVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGS 230 Query: 300 VDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKT 359 +++L +A+GA + +Y++ C + +LP I+F LGG+ Y L Y+ + S + K Sbjct: 231 TSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK 289 Query: 360 ICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 +C MDIPPP+GP W LG FI +YT FDR NR+GFA A Sbjct: 290 LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 334 >5N71-A nrPDB Length = 345 Score = 405 bits (1042), Expect = e-113, Method: Composition-based stats. Identities = 172/348 (49%), Positives = 234/348 (67%), Gaps = 17/348 (4%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 + P E L N LD YYG I IGTPPQ F V+FDTGS+NLW+PS C C HH+Y Sbjct: 3 EGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKY--CLHHHRY 60 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV 183 +S KSSTY +G +F I YGSG++ G++S+D +G KV Q GEA G Sbjct: 61 DSSKSSTYEADGRNFTIVYGSGNVEGFISKDV------CRIGSAKVSGQPLGEALVVGGE 114 Query: 184 VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLV-EKNIFSFYLNRDPTGQPGGELML 242 + A FDGILG+ YP I+V+ V+PVFDN+MKQ L+ E+N+FS YLNRDP+ + GGE++ Sbjct: 115 SLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLF 174 Query: 243 GGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT-----LCKGGCEAIVDTGTSLLV 297 GG D +Y G ++Y+ VT K YWQ H+D ++ S LCK GCEAI +TGTSL+ Sbjct: 175 GGIDHDHYKGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLIT 234 Query: 298 GPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAG 357 GP +EV L + +G G+Y++ C+K+ SLP +TF + G+ + L + Y+LKV+Q G Sbjct: 235 GPPEEVDSLNQYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQG 294 Query: 358 KTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +T+C+SGFMG+++P P LWILGDVF+G YYT+FDR+ +RVGFA+ A Sbjct: 295 QTLCVSGFMGLEMPQP---LWILGDVFLGPYYTIFDRDQDRVGFAEVA 339 >1PSO-E nrPDB Length = 326 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 162/337 (48%), Positives = 211/337 (62%), Gaps = 14/337 (4%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 + L+NYLD +Y+G IGIGTP Q FTVVFDTGSSNLWVPS++C L AC H+++N + S Sbjct: 4 QPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSL--ACTNHNRFNPEDS 61 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 STY + I YG+GS++G L DTV V GGI QIFG + +PG A Sbjct: 62 STYQSTSETVSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYA 115 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 FDGILG+ YP IS + PVFDN+ Q LV +++FS YL+ Q G ++ GG DS Sbjct: 116 PFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLS--ADDQSGSVVIFGGIDSS 173 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 YY G L+++ VT + YWQ+ +D + + E C GC+AIVDTGTSLL GP + +Q Sbjct: 174 YYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQS 233 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 IGA G+ ++ C +SSLP I F + G Y + P YIL+ + C+SGF GM Sbjct: 234 DIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGS----CISGFQGM 289 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 ++P SG LWILGDVFI Y+TVFDR N+VG A A Sbjct: 290 NLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA 326 >4PEP-A nrPDB Length = 326 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 167/337 (49%), Positives = 210/337 (62%), Gaps = 14/337 (4%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 E L+NYLD +Y+G IGIGTP Q FTV+FDTGSSNLWVPS++C L AC H+++N D S Sbjct: 4 EPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDS 61 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 ST+ I YG+GS++G L DTV V GGI QIFG + +PG A Sbjct: 62 STFEATSQELSITYGTGSMTGILGYDTVQV------GGISDTNQIFGLSETEPGSFLYYA 115 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 FDGILG+ YP IS + PVFDNL Q LV +++FS YL+ + G ++LGG DS Sbjct: 116 PFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDS--GSVVLLGGIDSS 173 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 YY G L+++ V+ + YWQ+ +D + + E C GGC+AIVDTGTSLL GP + +Q Sbjct: 174 YYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQS 233 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 IGA GE +I C + SLP I F + G Y L P YIL+ + C SGF GM Sbjct: 234 DIGASENSDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDS----CTSGFEGM 289 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 D+P SG LWILGDVFI YYTVFDR N+VG A A Sbjct: 290 DVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA 326 >4AA9-A nrPDB Length = 320 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 155/336 (46%), Positives = 210/336 (62%), Gaps = 19/336 (5%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 E L +YLD+QY+G+I IGTPPQ FTVVFDTGSS+LWVPSI+CK C HH+++ KS Sbjct: 3 EPLTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCK--SNVCKNHHRFDPRKS 60 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 ST+ G IHYG+GS+ G+L DTV+V I Q G +T+QPG VF + Sbjct: 61 STFRNLGKPLSIHYGTGSMEGFLGYDTVTVS------NIVDPNQTVGLSTEQPGEVFTYS 114 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 +FDGILG+ YP ++ +PVFDN+M + LV +++FS Y++R+ G L LG D Sbjct: 115 EFDGILGLAYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRN---GQGSMLTLGAIDPS 171 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 YY G L ++ VT + YWQ +D + + C GGC+AI+DTGTS+L GP ++ ++Q Sbjct: 172 YYTGSLHWVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQM 231 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 AIGA GE+ + C + S+P + F++ G++Y L P Y K + C SGF G Sbjct: 232 AIGATENRYGEFDVNCGNLRSMPTVVFEINGRDYPLSPSAYTSK----DQGFCTSGFQGD 287 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + LWILGDVFI YY+VFDR NRVG AKA Sbjct: 288 ----NNSELWILGDVFIREYYSVFDRANNRVGLAKA 319 >4CMS-A nrPDB Length = 323 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 152/341 (44%), Positives = 206/341 (60%), Gaps = 19/341 (5%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 E S L NYLD+QY+G+I +GTPPQ FTV+FDTGSS+ WVPSI+CK AC H ++ Sbjct: 1 GEVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK--SNACKNHQRF 58 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV 183 + KSST+ G IHYG+GS+ G L DTV+V I +Q G +T++PG Sbjct: 59 DPRKSSTFQNLGKPLSIHYGTGSMQGILGYDTVTVS------NIVDIQQTVGLSTQEPGD 112 Query: 184 VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLG 243 VF A+FDGILGM YP ++ +PVFDN+M + LV +++FS Y++R+ L LG Sbjct: 113 VFTYAEFDGILGMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRNGQES---MLTLG 169 Query: 244 GTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEV 303 D YY G L ++ VT + YWQ +D + + + C+GGC+AI+DTGTS LVGP ++ Sbjct: 170 AIDPSYYTGSLHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDI 229 Query: 304 KELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLS 363 +Q+AIGA GE+ I C+ +S +P + F++ G+ Y L P Y + C S Sbjct: 230 LNIQQAIGATQNQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYT----SQDQGFCTS 285 Query: 364 GFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 GF WILGDVFI YY+VFDR N VG AKA Sbjct: 286 GFQS----ENHSQKWILGDVFIREYYSVFDRANNLVGLAKA 322 >1AM5-A nrPDB Length = 324 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 160/339 (47%), Positives = 206/339 (60%), Gaps = 16/339 (4%) Query: 67 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 126 V+E +KN D +YYG I IGTPP+ F V+FDTGSSNLWV S HC AC H+K+ Sbjct: 2 VTEQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQ--ACSNHNKFKPR 59 Query: 127 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI 186 +SSTYV+ G + D+ YG+G + G L QDTVSV GG Q GE+ +PG Sbjct: 60 QSSTYVETGKTVDLTYGTGGMRGILGQDTVSV------GGGSDPNQELGESQTEPGPFQA 113 Query: 187 AAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 AA FDGILG+ YP I+ +PVFDN+ Q LVEK++FSFYL+ G G E+MLGG D Sbjct: 114 AAPFDGILGLAYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGG--GANGSEVMLGGVD 171 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 + +Y G + ++ VT + YWQV +D + V + C+ GC+AIVDTGTS +V PV + + Sbjct: 172 NSHYTGSIHWIPVTAEKYWQVALDGITVNGQTAACE-GCQAIVDTGTSKIVAPVSALANI 230 Query: 307 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 K IGA QGE M C V SLP ITF + G L P YI + + C SG Sbjct: 231 MKDIGASEN-QGEMMGNCASVQSLPDITFTINGVKQPLPPSAYI----EGDQAFCTSGLG 285 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +P + LWI GDVF+ YYT++DR N+VGFA AA Sbjct: 286 SSGVPSNTSELWIFGDVFLRNYYTIYDRTNNKVGFAPAA 324 >1FMX-A nrPDB Length = 329 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 150/337 (44%), Positives = 206/337 (61%), Gaps = 14/337 (4%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 L NYL+AQYY +I +GTPPQ F V+ DTGSSNLWVPS C +AC++H KY+ + S Sbjct: 5 VPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNEC--GSLACFLHSKYDHEAS 62 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAA 188 S+Y NGT F I YG+GSL GY+SQDT+S+ G + + KQ F EAT +PG+ F Sbjct: 63 SSYKANGTEFAIQYGTGSLEGYISQDTLSI------GDLTIPKQDFAEATSEPGLTFAFG 116 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYL-NRDPTGQPGGELMLGGTDS 247 KFDGILG+GY ISV+KV+P F N ++Q L+++ F+FYL + + GGE GG D Sbjct: 117 KFDGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDE 176 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 + G++++L V RKAYW+V + + +G E + AI DTGTSL+ P + + Sbjct: 177 SKFKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAI-DTGTSLITLPSGLAEMIN 235 Query: 308 KAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 IGA G+Y + C +LP + F G N+ + P Y L+VS + C+S Sbjct: 236 AEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGS----CISAITP 291 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 MD P P GPL I+GD F+ YY+++D N VG AKA Sbjct: 292 MDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKA 328 >1AVF-A nrPDB Length = 329 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 143/347 (41%), Positives = 210/347 (60%), Gaps = 20/347 (5%) Query: 61 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 120 T EP++ Y+DA Y+GEI IGTPPQ F V+FDTGSSNLWVPS++C+ AC H Sbjct: 1 SVTYEPMA-----YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSH 53 Query: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 180 ++N +SSTY NG +F + YGSGSL+G+ DT++V I+V Q FG + + Sbjct: 54 SRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQS------IQVPNQEFGLSENE 107 Query: 181 PGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 240 PG F+ A+FDGI+G+ YP +SV++ ++++ + +FS YL+ + G GG + Sbjct: 108 PGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLS-NQQGSSGGAV 166 Query: 241 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGP 299 + GG DS Y G++ + VT++ YWQ+ +++ +G + + C GC+AIVDTGTSLL P Sbjct: 167 VFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVP 226 Query: 300 VDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKT 359 + L +A GA G++++ C + +LP +TF + G + L P YIL + Sbjct: 227 QQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYIL----SNNG 282 Query: 360 ICLSGFMGMDIPPPSG-PLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 C G + +G PLWILGDVF+ YY+V+D NRVGFA AA Sbjct: 283 YCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA 329 >1MIQ-A nrPDB Length = 375 Score = 347 bits (891), Expect = 4e-96, Method: Composition-based stats. Identities = 105/359 (29%), Positives = 177/359 (49%), Gaps = 20/359 (5%) Query: 50 GPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIH 109 M+ + E L + + +YGE +G Q F ++FDTGS+NLWVPS Sbjct: 35 NFFKSGYMKQNYLGSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKK 94 Query: 110 CKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKV 169 C C + + Y+S KS +Y K+GT DI YGSG++ G+ S+D V+ LG + + Sbjct: 95 CN--SSGCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVT------LGHLSM 146 Query: 170 EKQIFGEATKQPG--VVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFY 227 + F E T ++ + +FDGILG+G+ +S+ + P+ L Q ++ +F+FY Sbjct: 147 PYK-FIEVTDTDDLEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFY 205 Query: 228 LNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEA 287 L G L +GG + ++Y G ++Y + YWQ+ +D + G + Sbjct: 206 LPVHDVHA--GYLTIGGIEEKFYEGNITYEKLNHDLYWQIDLD-VHFGKQTM---EKANV 259 Query: 288 IVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPE 347 IVD+GT+ + P + + + + + + + + +P + FK Y L PE Sbjct: 260 IVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPE 319 Query: 348 KYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 Y+ + + T+C+ + +DI + +ILGD F+ Y+TVFD + VGFA A Sbjct: 320 YYMNPILEVDDTLCMITMLPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIAKN 375 >2BJU-A nrPDB Length = 453 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 115/351 (32%), Positives = 184/351 (52%), Gaps = 20/351 (5%) Query: 58 QSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIAC 117 +++ + L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C Sbjct: 119 KTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGC 176 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 H Y+S KS TY K+GT +++Y SG++SG+ S+D V+V G + + + F E Sbjct: 177 LTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEV 229 Query: 178 TKQPGV--VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ 235 G + A+ FDGILG+G+ +S+ V P+ L Q +E +F+FYL + Sbjct: 230 IDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHD--K 287 Query: 236 PGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSL 295 G L +GG + R+Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS Sbjct: 288 HTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSA 343 Query: 296 LVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQ 355 + P D + ++ + + + + + + S LP F Y L PE Y+ + Sbjct: 344 ITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIED 403 Query: 356 AGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 G +C+ +G+D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 404 VGPGLCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAKK 451 >2ANL-A nrPDB Length = 327 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 110/338 (32%), Positives = 175/338 (51%), Gaps = 20/338 (5%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L + + +YGE +G Q F ++FDTGS+NLWVPS C I C H Y+S KS + Sbjct: 8 LDDVANLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCN--SIGCSTKHLYDSSKSKS 65 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPG--VVFIAA 188 Y K+GT +I YGSG++ G+ S+D V+ LG + + + F E T ++ AA Sbjct: 66 YEKDGTKVEITYGSGTVRGFFSKDLVT------LGYLSLPYK-FIEVTDTDDLEPLYTAA 118 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 +FDGILG+G+ +S+ + P+ L Q +++ +F+FYL + G L +GG + + Sbjct: 119 EFDGILGLGWKDLSIGSIDPIVVELKNQNKIDQALFTFYLPVHD--KHSGYLTIGGIEEK 176 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 +Y GEL+Y + +WQV +D + G IVD+GTS + P + + K Sbjct: 177 FYEGELTYEKLNHDLFWQVDLD-VNFGKTSM---EKANVIVDSGTSTITAPTSFINKFFK 232 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 + + + + I +P + FK Y L PE Y+ + T+C+ + + Sbjct: 233 DLNVIKVPFLPFYITTCNNKDMPTLEFKSANNTYTLEPEYYMEPLLDIDDTLCMLYILPV 292 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 DI + +ILGD F+ Y+TVFD + +GFA A Sbjct: 293 DIDKNT---FILGDPFMRKYFTVFDYDKESIGFAVAKN 327 >5BWY-A nrPDB Length = 376 Score = 342 bits (877), Expect = 2e-94, Method: Composition-based stats. Identities = 115/351 (32%), Positives = 184/351 (52%), Gaps = 20/351 (5%) Query: 58 QSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIAC 117 +++ + L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C Sbjct: 42 KTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGC 99 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 H Y+S KS TY K+GT +++Y SG++SG+ S+D V+V G + + + F E Sbjct: 100 LTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEV 152 Query: 178 TKQPGV--VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ 235 G + A+ FDGILG+G+ +S+ V P+ L Q +E +F+FYL + Sbjct: 153 IDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHD--K 210 Query: 236 PGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSL 295 G L +GG + R+Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS Sbjct: 211 HTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSA 266 Query: 296 LVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQ 355 + P D + ++ + + + + + + S LP F Y L PE Y+ + Sbjct: 267 ITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIED 326 Query: 356 AGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 G +C+ +G+D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 327 VGPGLCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAKK 374 >4OC6-B nrPDB Length = 243 Score = 342 bits (877), Expect = 2e-94, Method: Composition-based stats. Identities = 204/243 (83%), Positives = 223/243 (91%) Query: 165 GGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIF 224 GG+KVE+Q+FGEATKQPG+ FIAAKFDGILGM YP ISVN VLPVFDNLM+QKLV++NIF Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIF 60 Query: 225 SFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGG 284 SFYL+RDP QPGGELMLGGTDS+YY G LSYLNVTRKAYWQVH+DQ+EV S LTLCK G Sbjct: 61 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 120 Query: 285 CEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYEL 344 CEAIVDTGTSL+VGPVDEV+ELQKAIGAVPLIQGEYMIPCEKVS+LP IT KLGG+ Y+L Sbjct: 121 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 180 Query: 345 HPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 PE Y LKVSQAGKT+CLSGFMGMDIPPPSGPLWILGDVFIG YYTVFDR+ NRVGFA+A Sbjct: 181 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 Query: 405 ATL 407 A L Sbjct: 241 ARL 243 >1QS8-A nrPDB Length = 329 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 103/347 (29%), Positives = 173/347 (49%), Gaps = 20/347 (5%) Query: 62 RTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHH 121 E L + + +YGE +G Q F ++FDTGS+NLWVPS C C + + Sbjct: 1 LGSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCN--SSGCSIKN 58 Query: 122 KYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQP 181 Y+S KS +Y K+GT DI YGSG++ G+ S+D V+ LG + + + F E Sbjct: 59 LYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVT------LGHLSMPYK-FIEVIDTD 111 Query: 182 G--VVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGE 239 ++ + +FDGILG+G+ +S+ + P+ L Q ++ +F+FYL G Sbjct: 112 DLEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHA--GY 169 Query: 240 LMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGP 299 L +GG + ++Y G ++Y + YWQ+ +D + G + IVD+GT+ + P Sbjct: 170 LTIGGIEEKFYEGNITYEKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAP 225 Query: 300 VDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKT 359 + + + + + + + + +P + FK Y L PE Y+ + + T Sbjct: 226 SEFLNKFFANLNVIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPEYYMNPILEVDDT 285 Query: 360 ICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 +C+ + +DI + +ILGD F+ Y+TVFD + VGFA A Sbjct: 286 LCMITMLPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIAKN 329 >3QS1-A nrPDB Length = 336 Score = 338 bits (867), Expect = 3e-93, Method: Composition-based stats. Identities = 115/341 (33%), Positives = 179/341 (52%), Gaps = 20/341 (5%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 S L + + YYGE IG Q F +FDTGS+NLWVPS C I C + Y+S+K Sbjct: 12 SVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNT--IGCKTKNLYDSNK 69 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VF 185 S TY K+GT +++Y SG++SG+ S+D V++ + + F E T G + Sbjct: 70 SKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIA------NLSFPYK-FIEVTDTNGFEPAY 122 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 +FDGI+G+G+ +S+ V PV L Q +E+ +F+FYL D + G L +GG Sbjct: 123 TLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHK--GYLTIGGI 180 Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKE 305 + R+Y G+L+Y + YWQV +D L G+ AIVD+GTS + P + + + Sbjct: 181 EDRFYEGQLTYEKLNHDLYWQVDLD-LHFGNLTV---EKATAIVDSGTSSITAPTEFLNK 236 Query: 306 LQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGF 365 + + V + I LP + F+ Y L PE Y+ ++ G ++C+ Sbjct: 237 FFEGLDVVKIPFLPLYITTCNNPKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLCMVSI 296 Query: 366 MGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 + +D+ + +ILGD F+ Y+TVFD + + VGFA A Sbjct: 297 IPVDLNKNT---FILGDPFMRKYFTVFDYDNHTVGFALAKK 334 >1XDH-A nrPDB Length = 331 Score = 338 bits (867), Expect = 3e-93, Method: Composition-based stats. Identities = 115/338 (34%), Positives = 180/338 (53%), Gaps = 20/338 (5%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L ++ + +YG+ +G Q FT + DTGS+NLWVPS+ C C H Y+S KS T Sbjct: 10 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKHLYDSSKSRT 67 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFIAA 188 Y K+GT +++Y SG++SG+ S+D V+V G + + + F E G + A+ Sbjct: 68 YEKDGTKVEMNYVSGTVSGFFSKDLVTV------GNLSLPYK-FIEVIDTNGFEPTYTAS 120 Query: 189 KFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 FDGILG+G+ +S+ V P+ L Q +E +F+FYL + G L +GG + R Sbjct: 121 TFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHD--KHTGFLTIGGIEER 178 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 +Y G L+Y + YWQ+ +D VG+ + L K C IVD+GTS + P D + ++ + Sbjct: 179 FYEGPLTYEKLNHDLYWQITLDA-HVGN-IMLEKANC--IVDSGTSAITVPTDFLNKMLQ 234 Query: 309 AIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 + + + + + S LP F Y L PE Y+ + G +C+ +G+ Sbjct: 235 NLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGL 294 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 D P P+ +ILGD F+ Y+TVFD + + VG A A Sbjct: 295 DFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAKK 329 >5JOD-A nrPDB Length = 375 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 115/358 (32%), Positives = 177/358 (49%), Gaps = 20/358 (5%) Query: 52 ITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCK 111 Q E S L + + +YGE IGT Q F +FDTGS+NLWVPS++C Sbjct: 36 FKSGYAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCD 95 Query: 112 LLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEK 171 I C H Y++ S +Y K+GT +I YGSG++ GY S+D +S LG + + Sbjct: 96 --SIGCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVIS------LGDLSLPY 147 Query: 172 QIFGEATKQPG--VVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLN 229 + F E T ++ ++FDGILG+G+ +S+ + PV L KQ ++ +F+FYL Sbjct: 148 K-FIEVTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLP 206 Query: 230 RDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIV 289 G L +GG +S +Y G L+Y + YWQ+ +D + G + A+V Sbjct: 207 VHDKHV--GYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVV 260 Query: 290 DTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKY 349 D+GTS + P + + + + + + + LP + F Y L PE Y Sbjct: 261 DSGTSTITAPTSFLNKFFRDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFY 320 Query: 350 ILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 + +S +C+ + +DI + +ILGD F+ Y+TVFD E VGFA A L Sbjct: 321 MDPLSDIDPALCMLYILPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAKNL 375 >5I70-B nrPDB Length = 328 Score = 335 bits (859), Expect = 2e-92, Method: Composition-based stats. Identities = 114/346 (32%), Positives = 176/346 (50%), Gaps = 20/346 (5%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 E S L + + +YGE IGT Q F +FDTGS+NLWVPS++C I C H Y Sbjct: 1 SENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCD--SIGCSTKHLY 58 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPG- 182 ++ S +Y K+GT +I YGSG++ GY S+D +S LG + + + F E T Sbjct: 59 DASASKSYEKDGTKVEISYGSGTVRGYFSKDVIS------LGDLSLPYK-FIEVTDADDL 111 Query: 183 -VVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELM 241 ++ ++FDGILG+G+ +S+ + PV L KQ ++ +F+FYL G L Sbjct: 112 EPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHV--GYLT 169 Query: 242 LGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVD 301 +GG +S +Y G L+Y + YWQ+ +D + G + A+VD+GTS + P Sbjct: 170 IGGIESDFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTS 225 Query: 302 EVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTIC 361 + + + + + + + LP + F Y L PE Y+ +S +C Sbjct: 226 FLNKFFRDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALC 285 Query: 362 LSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 + + +DI + +ILGD F+ Y+TVFD E VGFA A L Sbjct: 286 MLYILPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAKNL 328 >1QDM-A nrPDB Length = 478 Score = 321 bits (822), Expect = 4e-88, Method: Composition-based stats. Identities = 141/310 (45%), Positives = 191/310 (61%), Gaps = 16/310 (5%) Query: 22 IRIPLRKFTSIR--RTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQY 79 +RI L+K R R T + G E +L G S + LKNY++AQY Sbjct: 1 VRIALKKRPIDRNSRVATGLSGGEEQPLLSGANPLRSEEEGDI------VALKNYMNAQY 54 Query: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFD 139 +GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H +Y + SSTY KNG Sbjct: 55 FGEIGVGTPPQKFTVIFDTGSSNLWVPSAKC-YFSIACYLHSRYKAGASSTYKKNGKPAA 113 Query: 140 IHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYP 199 I YG+GS++GY S+D+V+V G + V+ Q F EATK+PG+ F+ AKFDGILG+G+ Sbjct: 114 IQYGTGSIAGYFSEDSVTV------GDLVVKDQEFIEATKEPGITFLVAKFDGILGLGFK 167 Query: 200 FISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNV 259 ISV K +PV+ +++Q LV +FSF+LNR GGE++ GG D ++Y GE +Y+ V Sbjct: 168 EISVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYVPV 227 Query: 260 TRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQG 318 T+K YWQ M + VG + T C GGC AI D+GTSLL GP + E+ + IGA ++ Sbjct: 228 TQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAAGVVSQ 287 Query: 319 EYMIPCEKVS 328 E + Sbjct: 288 ECKTIVSQYG 297 Score = 128 bits (321), Expect = 5e-30, Method: Composition-based stats. Identities = 51/104 (49%), Positives = 67/104 (64%) Query: 302 EVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTIC 361 + + + +P GE + C + S+P I F +GG+ + L PE+YILKV + C Sbjct: 375 ILDYVNQLCNRLPSPMGESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQC 434 Query: 362 LSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +SGF MDIPPP GPLWILGDVF+G Y+TVFD R+GFAKAA Sbjct: 435 ISGFTAMDIPPPRGPLWILGDVFMGPYHTVFDYGKLRIGFAKAA 478 >3QVI-A nrPDB Length = 451 Score = 312 bits (800), Expect = 1e-85, Method: Composition-based stats. Identities = 95/358 (26%), Positives = 172/358 (48%), Gaps = 20/358 (5%) Query: 52 ITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCK 111 K + S E + LK+ + +GE +G Q F +F T SSN+WVPSI C Sbjct: 112 FNKGLTKKSYLGSEFDNVELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCT 171 Query: 112 LLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEK 171 +C + Y+S KS TY K+ T + +G++SG S+D V++ G + V Sbjct: 172 --SESCESKNHYDSSKSKTYEKDDTPVKLTSKAGTISGIFSKDLVTI------GKLSVPY 223 Query: 172 QIFGEATKQPGV--VFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLN 229 + F E T+ G + + DG+ G+G+ +S+ + P L Q +E+ ++S YL Sbjct: 224 K-FIEMTEIVGFEPFYSESDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP 282 Query: 230 RDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIV 289 P + G L +GG + R++ G L+Y + WQV +D + G+ + I+ Sbjct: 283 --PENKNKGYLTIGGIEERFFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVIL 336 Query: 290 DTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKY 349 D+ TS++ P + + ++ + + + LP + ++ + Y L P++Y Sbjct: 337 DSATSVITVPTEFFNQFVESASVFKVPFLSLYVTTCGNTKLPTLEYRSPNKVYTLEPKQY 396 Query: 350 ILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 + + +C+ + +D+ + ++LGD F+ Y+TV+D + + VGFA A L Sbjct: 397 LEPLENIFSALCMLNIVPIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAKNL 451 >3FNT-A nrPDB Length = 332 Score = 306 bits (785), Expect = 8e-84, Method: Composition-based stats. Identities = 92/341 (26%), Positives = 167/341 (48%), Gaps = 20/341 (5%) Query: 69 ELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128 LK+ + +GE +G Q F +F T SSN+WVPSI C +C + Y+S KS Sbjct: 10 VELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCT--SESCESKNHYDSSKS 67 Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV--VFI 186 TY K+ T + +G++SG S+D V++ G + V + F E T+ G + Sbjct: 68 KTYEKDDTPVKLTSKAGTISGIFSKDLVTI------GKLSVPYK-FIEMTEIVGFEPFYS 120 Query: 187 AAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 + DG+ G+G+ +S+ + P L Q +E+ ++S YL P + G L +GG + Sbjct: 121 ESDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP--PENKNKGYLTIGGIE 178 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 R++ G L+Y + WQV +D + G+ + I+D+ TS++ P + + Sbjct: 179 ERFFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQF 234 Query: 307 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 ++ + + + LP + ++ + Y L P++Y+ + +C+ + Sbjct: 235 VESASVFKVPFLSLYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIV 294 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL 407 +D+ + ++LGD F+ Y+TV+D + + VGFA A L Sbjct: 295 PIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAKNL 332 >1B5F-A nrPDB Length = 239 Score = 284 bits (726), Expect = 5e-77, Method: Composition-based stats. Identities = 114/249 (45%), Positives = 155/249 (62%), Gaps = 12/249 (4%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYN 124 L N D Y+GEIGIGTPPQ FTV+FDTGSS LWVPS C + AC H Y Sbjct: 1 GSAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKC-INSKACRAHSMYE 59 Query: 125 SDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVV 184 S SSTY +NGT I YG+GS++G+ SQD+V++ G + V++Q F EAT + V Sbjct: 60 SSDSSTYKENGTFGAIIYGTGSITGFFSQDSVTI------GDLVVKEQDFIEATDEADNV 113 Query: 185 FIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGG 244 F+ FDGILG+ + ISV PV+ N++ Q LV++ FSF+LNR+ + GGEL+ GG Sbjct: 114 FLHRLFDGILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGG 169 Query: 245 TDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT-LCKGGCEAIVDTGTSLLVGPVDEV 303 D ++ G+ +Y+ VT + YWQ + + +G + T C GC+A D+GTSLL GP V Sbjct: 170 LDPNHFRGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIV 229 Query: 304 KELQKAIGA 312 ++ AIGA Sbjct: 230 TQINHAIGA 238 >3LIZ-A nrPDB Length = 334 Score = 276 bits (707), Expect = 9e-75, Method: Composition-based stats. Identities = 93/342 (27%), Positives = 163/342 (47%), Gaps = 22/342 (6%) Query: 66 PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNS 125 P+ +L+ +++ QY G IG Q F VFD+ S N+ V S C C KY Sbjct: 8 PLYKLVHVFINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEK 65 Query: 126 DKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVF 185 K Y+ +G + +GS G +D++++ + + + + Q + Sbjct: 66 LKPK-YISDGNVQVKFFDTGSAVGRGIEDSLTISQLTT----SQQDIVLADELSQEVCIL 120 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 A GI G P + K V +N +++ L+ +FS + R G+ GE++ GG+ Sbjct: 121 SADVVVGIAAPGCP--NALKGKTVLENFVEENLIAP-VFSIHHARFQDGEHFGEIIFGGS 177 Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKE 305 D +Y GE +Y+ + W+ +D +++G + T+ G +AI+DT +++VGP V Sbjct: 178 DWKYVDGEFTYVPLVGDDSWKFRLDGVKIG-DTTVAPAGTQAIIDTSKAIIVGPKAYVNP 236 Query: 306 LQKAIGAV---PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 + +AIG V + + C K+ SLP +TF + G+N+ + + YI Q +C Sbjct: 237 INEAIGCVVEKTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYI----QQNGNLCY 292 Query: 363 SGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 SGF P + +GD F+ YY+ F+ E +GF ++ Sbjct: 293 SGFQ----PCGHSDHFFIGDFFVDHYYSEFNWENKTMGFGRS 330 >1UH8-A nrPDB Length = 325 Score = 257 bits (657), Expect = 6e-69, Method: Composition-based stats. Identities = 108/343 (31%), Positives = 176/343 (51%), Gaps = 28/343 (8%) Query: 68 SELLKNYL-DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHH-KYNS 125 + + +Y D +YYG++ IGTP + F + FDTGSS+LW+ S C C KY+ Sbjct: 5 TVPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCT----NCGSRQTKYDP 60 Query: 126 DKSSTYVKNGTSFDIHYGSG-SLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVV 184 ++SSTY +G ++ I YG G S SG L++D V +LGG+ ++ Q A ++ Sbjct: 61 NQSSTYQADGRTWSISYGDGSSASGILAKDNV------NLGGLLIKGQTIELAKREAAS- 113 Query: 185 FIAAKFDGILGMGYPFI-SVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLG 243 F + DG+LG+G+ I +V V DNL+ Q L+ + IF YL + GGE + G Sbjct: 114 FASGPNDGLLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGK-AKNGGGGEYIFG 172 Query: 244 GTDSRYYHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDE 302 G DS + G L+ + + + +W + +D+ VG+ + I+DTGT+LL+ P + Sbjct: 173 GYDSTKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASS--FDGILDTGTTLLILPNNI 230 Query: 303 VKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 + +A GA G Y I C+ P++ F + G ++++ P+ + + Q G+ I Sbjct: 231 AASVARAYGASDNGDGTYTISCDTSRFKPLV-FSINGASFQVSPDSLVFEEFQ-GQCIAG 288 Query: 363 SGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 G+ D I+GD F+ Y VF++ V A A Sbjct: 289 FGYGNWDFA-------IIGDTFLKNNYVVFNQGVPEVQIAPVA 324 >5HCT-A nrPDB Length = 419 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 96/395 (24%), Positives = 152/395 (38%), Gaps = 38/395 (9%) Query: 22 IRIPLRKFT---SIRRTMTEVG----GSVEDLILKGPITKYSMQSSPRTKEPVSELLKNY 74 +R P KF S+++T + G +ED + + T P+ + Sbjct: 47 VRNPNYKFNGPLSVKKTYLKYGVPIPAWLEDAVQNSTSGLAERSTGSATTTPI-----DS 101 Query: 75 LDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKN 134 LD Y + IGTP Q + FDTGSS+LWV S ++ + + ++ + Sbjct: 102 LDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSG 161 Query: 135 GTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 T + S SG + DTVSV GG+ V Q A K + DG+L Sbjct: 162 ATWSISYGDGSSSSGDVYTDTVSV------GGLTVTGQAVESAKKVSSSFTEDSTIDGLL 215 Query: 195 GMGYPFISV---NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYH 251 G+ + ++ + FDN ++ +F+ L G G D+ Y Sbjct: 216 GLAFSTLNTVSPTQQKTFFDNAKAS--LDSPVFTADLGYHAP----GTYNFGFIDTTAYT 269 Query: 252 GELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAI 310 G ++Y V T++ +W+ VGS T + I DTGT+LL P V + Sbjct: 270 GSITYTAVSTKQGFWEWTSTGYAVGSG-TFKSTSIDGIADTGTTLLYLPATVVSAYWAQV 328 Query: 311 GAVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 G Y+ PC ++LP TF +G + + G + C G Sbjct: 329 SGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQS- 385 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDRE-YNRVGFA 402 + I GDV + + VF+ +GFA Sbjct: 386 ---SAGIGINIFGDVALKAAFVVFNGATTPTLGFA 417 >2ASI-A nrPDB Length = 361 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 94/354 (26%), Positives = 160/354 (45%), Gaps = 41/354 (11%) Query: 78 QYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTS 137 +Y + IGTP Q F ++FDTGSS+ WVP C + C ++ SST+ + Sbjct: 19 EYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSE-GCVGSRFFDPSASSTFKATNYN 77 Query: 138 FDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF-----DG 192 +I YG+G +G +D++++ G I V KQI G + DG Sbjct: 78 LNITYGTGGANGLYFEDSIAI------GDITVTKQILAYVDNVRGPTAEQSPNADIFLDG 131 Query: 193 ILGMGYPFISVNKVL------PVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 + G YP + + V NL KQ L+ +FS Y+N T GE++ GG + Sbjct: 132 LFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMN---TNSGTGEVVFGGVN 188 Query: 247 SRYYHGELSYLNVTRK----AYWQVHMDQLEVGSELTLCKGGCEAI-VDTGTSLLVGPVD 301 + G+++Y +V + +W + + V + +A +DTGT+ + P Sbjct: 189 NTLLGGDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFIMPSS 248 Query: 302 EVKELQK-AIGAVPLIQGEYMIPCEKV----SSLPIITFKLGGQNYEL----HPEKYILK 352 ++ K A+ Q +++PC S++ I+ K G + + K +L Sbjct: 249 AASKIVKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIEISVPVSKMLLP 308 Query: 353 VSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAAT 406 V Q+ +T C+ I P G +I+G++F+ + V+D NR+GFA A+ Sbjct: 309 VDQSNET-CMF-----IILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFAPLAS 356 >2QZW-A nrPDB Length = 341 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 90/354 (25%), Positives = 144/354 (40%), Gaps = 37/354 (10%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKL-------LDIAC 117 + + L N Y +I IG+ Q F V+ DTGSS+LWVP C Sbjct: 1 QAIPVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFC 59 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGE 176 Y S+T GT F I YG GS S G L +DTV GG + KQ+F + Sbjct: 60 KGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVG------FGGASITKQVFAD 113 Query: 177 ATKQPGVVFIAAKFDGILGMGYPFI-SVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ 235 TK + GILG+GY + V L Q ++ KN +S YLN Sbjct: 114 ITK-------TSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS--PNA 164 Query: 236 PGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSL 295 G+++ GG D Y G L + VT ++ ++ L+ + G + ++D+GT++ Sbjct: 165 ATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTI 222 Query: 296 LVGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVSSLPIITFKLGGQNYELHPEKYIL 351 D +++ A A G+ Y+ C+ ++ F + ++ Sbjct: 223 TYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTA 280 Query: 352 KVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 +S A + + ILGD F+ Y V+D + +++ A+ Sbjct: 281 PLSYANGQP----YPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVK 330 >4Y9W-A nrPDB Length = 334 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 94/343 (27%), Positives = 141/343 (41%), Gaps = 37/343 (10%) Query: 74 YLDAQYYG-EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYV 132 Y + YG + +G+ Q VV DTGSS+ WV C + ++ S+++ Sbjct: 8 YFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFK 67 Query: 133 KNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFD 191 G+SF I YG S S G QDT+ LGG + Q F + T + Sbjct: 68 SLGSSFSIGYGDKSSSIGTWGQDTI------YLGGTSITNQRFADVT-------STSVNQ 114 Query: 192 GILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDS 247 GILG+G + P +DN L KQ ++ N +S YLN G G ++ GG D+ Sbjct: 115 GILGVG--RVETESANPPYDNVPITLKKQGKIKTNAYSLYLNS--PGAATGTIIFGGVDN 170 Query: 248 RYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307 Y G+L + Y V++ L + + G +VD+GT++ P V +L Sbjct: 171 AKYSGKLIEEPLVSDRYLAVNLKSLNYNGDNS--NAGFGVVVDSGTTISYLPDSIVDDLA 228 Query: 308 KAIGA----VPLIQGEYMIPCE-KVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 +GA V L Y I C TF G + +++L Q+ C+ Sbjct: 229 NKVGAYLEPVGLGNELYFIDCNANPQGSASFTFD-NGAKITVPLSEFVL---QSTANACV 284 Query: 363 SGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 G D ILGD F+ Y VF+ + V A+ Sbjct: 285 WGLQSSDRQ---NVPPILGDNFLRHAYVVFNLDKETVSLAQVK 324 >3TPL-A nrPDB Length = 433 Score = 244 bits (624), Expect = 4e-65, Method: Composition-based stats. Identities = 95/361 (26%), Positives = 156/361 (43%), Gaps = 50/361 (13%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 107 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGY 198 + Y G+ +G L D VS+P + + V T+ + ++GILG+ Y Sbjct: 108 YVPYTQGAWAGELGTDLVSIPHGPN---VTVRAN-IAAITESDKFFINGSNWEGILGLAY 163 Query: 199 PFISV--NKVLPVFDNLMKQKLVEKNIFSFYL--------NRDPTGQPGGELMLGGTDSR 248 I+ + + P FD+L+KQ V N+FS L + GG +++GG D Sbjct: 164 AEIARPDDSLEPFFDSLVKQTHV-PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHS 222 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSE--LTLCK--GGCEAIVDTGTSLLVGPVDEVK 304 Y G L Y + R+ Y++V + ++E+ + CK ++IVD+GT+ L P + Sbjct: 223 LYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFE 282 Query: 305 ELQKAIGAVPLIQG-------EYMIPCEKVSS-----LPIITFKLGGQ------NYELHP 346 K+I A + + C + + P+I+ L G+ + P Sbjct: 283 AAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILP 342 Query: 347 EKYILKVSQAGKTI--CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 ++Y+ V + C + S ++G V + +Y VFDR R+GFA + Sbjct: 343 QQYLRPVEDVATSQDDCYKFAISQ-----SSTGTVMGAVIMEGFYVVFDRARKRIGFAVS 397 Query: 405 A 405 A Sbjct: 398 A 398 >3PVK-A nrPDB Length = 342 Score = 244 bits (622), Expect = 6e-65, Method: Composition-based stats. Identities = 88/354 (24%), Positives = 143/354 (40%), Gaps = 36/354 (10%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIH--CKLLDIA-----C 117 + V L N Y +I +G+ Q V+ DTGSS+LWVP ++ C++ C Sbjct: 1 QAVPVTLHNEQ-VTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFC 59 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGE 176 Y+ SS T F I YG GS S G L +DTV GG+ ++ Q+ + Sbjct: 60 KQKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVG------FGGVSIKNQVLAD 113 Query: 177 ATKQPGVVFIAAKFDGILGMGYPFI-SVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ 235 + GILG+GY + V L KQ ++ KN +S YLN Sbjct: 114 VD-------STSIDQGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAAT 166 Query: 236 PGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSL 295 G+++ GG D+ Y G L L VT ++ + +EV + T+ + ++D+GT++ Sbjct: 167 --GQIIFGGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGK-TINTDNVDVLLDSGTTI 223 Query: 296 LVGPVDEVKELQKAIGAV----PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYIL 351 D ++ KA Y + C +S + F + + ++ Sbjct: 224 TYLQQDLADQIIKAFNGKLTQDSNGNSFYEVDC-NLSGDVVFNFSKNAK-ISVPASEFAA 281 Query: 352 KVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 + Q + ILGD F+ Y V+D + N + A+ Sbjct: 282 SL-QGDDGQPYDKCQ---LLFDVNDANILGDNFLRSAYIVYDLDDNEISLAQVK 331 >2QZX-A nrPDB Length = 342 Score = 243 bits (621), Expect = 8e-65, Method: Composition-based stats. Identities = 90/364 (24%), Positives = 140/364 (38%), Gaps = 56/364 (15%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDI-------AC 117 PV+ L N Y +I +G+ Q V+ DTGSS+LW+P + + C Sbjct: 1 GPVAVTLHNEA-ITYTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFC 59 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGE 176 Y+ S T T FDI YG GS G L +DTV + GG+ V Q+F Sbjct: 60 KSAGSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGI------GGVSVRDQLFAN 113 Query: 177 ATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDP 232 + + GILG+G+ + +DN L Q ++ K +S YLN Sbjct: 114 V-------WSTSARKGILGIGFQSGEATEFD--YDNLPISLRNQGIIGKAAYSLYLNSAE 164 Query: 233 TGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTG 292 G+++ GG D Y G L L +T + V + + V ++D+G Sbjct: 165 AST--GQIIFGGIDKAKYSGSLVDLPITSEKKLTVGLRSVNVRGRNV--DANTNVLLDSG 220 Query: 293 TSLLVGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVSSLPIITFKLGGQNYELHPEK 348 T++ V+ + AIGA Y+ C+ + I F+ G Sbjct: 221 TTISYFTRSIVRNILYAIGAQMKFDSAGNKVYVADCKTSGT---IDFQFGNN-------- 269 Query: 349 YILKVSQAGKTICLSGFMGMDIPPPSGPLW-------ILGDVFIGCYYTVFDREYNRVGF 401 LK+S + P P + ILGD F+ Y V++ + ++ Sbjct: 270 --LKISVPVSEFLFQTYYTSGKPFPKCEVRIRESEDNILGDNFLRSAYVVYNLDDKKISM 327 Query: 402 AKAA 405 A Sbjct: 328 APVK 331 >3ZKX-A nrPDB Length = 386 Score = 243 bits (621), Expect = 9e-65, Method: Composition-based stats. Identities = 96/355 (27%), Positives = 159/355 (44%), Gaps = 44/355 (12%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ IGTPPQ ++ DTGSSN V +D +++++SSTY G Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDT------YFDTERSSTYRSKGFDV 71 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGY 198 + Y GS +G++ +D V++P + + IF K++GILG+ Y Sbjct: 72 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFES----ENFFLPGIKWNGILGLAY 127 Query: 199 PFIS--VNKVLPVFDNLMKQKLVEKNIFSFY-----LNRDPTGQPGGELMLGGTDSRYYH 251 ++ + + FD+L+ Q + N+FS L +G GG L+LGG + Y Sbjct: 128 ATLAKPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYK 186 Query: 252 GELSYLNVTRKAYWQVHMDQLEVGSELTLCK----GGCEAIVDTGTSLLVGPVDEVKELQ 307 G++ Y + + Y+Q+ + +LE+G + +AIVD+GT+LL P + Sbjct: 187 GDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVV 246 Query: 308 KAI---GAVPLIQGEY----MIPCEKVSS-----LPIITFKLGGQN------YELHPEKY 349 +A+ +P + + C S P I+ L +N + P+ Y Sbjct: 247 EAVARASLIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLY 306 Query: 350 ILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 I + AG F I P + L ++G + +Y +FDR RVGFA + Sbjct: 307 IQPMMGAGLNYECYRF---GISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFAAS 357 >3FV3-A nrPDB Length = 339 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 91/343 (26%), Positives = 141/343 (41%), Gaps = 43/343 (12%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLD-IACWVHHKYNSDKSSTYVKNGTS 137 Y ++ +G+ Q TV+ DTGSS+ WV + + + C + SS+Y G + Sbjct: 14 YASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGAA 73 Query: 138 FDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGM 196 F I YG GS S G +DTV++ G+ + Q + T+ + GILG+ Sbjct: 74 FTIRYGDGSTSQGTWGKDTVTI------NGVSITGQQIADVTQ-------TSVDQGILGI 120 Query: 197 GYP------FISVNKVLPVFDN----LMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 246 GY S + P +DN L KQ + N +S YLN G ++ GG D Sbjct: 121 GYTSNEAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNS--PSAETGTIIFGGVD 178 Query: 247 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 306 + Y G+L VT + + + + G A++D+GT+L P D +L Sbjct: 179 NAKYSGKLVAEQVTSSQALTISLASVNLKGSSFSFGDG--ALLDSGTTLTYFPSDFAAQL 236 Query: 307 QKAIGA----VPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICL 362 GA V Q Y I C +S + G + +Y+ Q G CL Sbjct: 237 ADKAGARLVQVARDQYLYFIDCNTDTSGTTVFNFGNGAKITVPNTEYVY---QNGDGTCL 293 Query: 363 SGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 G D ILGD F+ Y +++ + N + A+ Sbjct: 294 WGIQPSD-------DTILGDNFLRHAYLLYNLDANTISIAQVK 329 >1J71-A nrPDB Length = 334 Score = 240 bits (612), Expect = 9e-64, Method: Composition-based stats. Identities = 88/338 (26%), Positives = 139/338 (41%), Gaps = 38/338 (11%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSI--HCKLLDIA-----CWVHHKYNSDKSSTY 131 Y +I +G+ Q TVV DTGSS+LWV C++ C ++ SS+ Sbjct: 14 YAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQEGTFDPSSSSSA 73 Query: 132 VKNGTSFDIHYGS-GSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 F I YG S G +DTV GGI ++ Q F + T + Sbjct: 74 QNLNQDFSIEYGDLTSSQGSFYKDTVG------FGGISIKNQQFADVTT-------TSVD 120 Query: 191 DGILGMGYPFISVNK--VLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSR 248 GI+G+G+ V L KQ ++ KN +S YLN + G+++ GG D+ Sbjct: 121 QGIMGIGFTADEAGYNLYDNVPVTLKKQGIINKNAYSLYLNSEDAST--GKIIFGGVDNA 178 Query: 249 YYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 Y G L+ L VT +VH+ + T + ++D+GT++ + + Sbjct: 179 KYTGTLTALPVTSSVELRVHLGSINFDG--TSVSTNADVVLDSGTTITYFSQSTADKFAR 236 Query: 309 AIGAVPLIQGE-YMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMG 367 +GA + E Y +P +S + F G + + ILK + +IC G Sbjct: 237 IVGATWDSRNEIYRLPSCDLSGDAVFNFDQ-GVKITVPLSELILK--DSDSSICYFGISR 293 Query: 368 MDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 D ILGD F+ Y V+D + + A+ Sbjct: 294 NDAN-------ILGDNFLRRAYIVYDLDDKTISLAQVK 324 >1MPP-A nrPDB Length = 361 Score = 237 bits (605), Expect = 6e-63, Method: Composition-based stats. Identities = 90/361 (24%), Positives = 161/361 (44%), Gaps = 41/361 (11%) Query: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 L ++ +Y + IGTP Q F ++FDTGSS+ WVP C + C ++ SST Sbjct: 12 LYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSE-GCVGKRFFDPSSSST 70 Query: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKF 190 + + + +I YG+G +G +D+++V GG V++Q G + Sbjct: 71 FKETDYNLNITYGTGGANGIYFRDSITV------GGATVKQQTLAYVDNVSGPTAEQSPD 124 Query: 191 -----DGILGMGYPFISV------NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGE 239 DGI G YP + + V NL KQ L+ +FS Y+N + G Sbjct: 125 SELFLDGIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVF 184 Query: 240 LMLGGTDSRYYHGELSYLNVTRKA----YWQVHMDQLEVGSELTLCKGGCEAI-VDTGTS 294 ++ G++ Y +V + +W + +++ + G +A +DTGT+ Sbjct: 185 GG---VNNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGSDAVSFDGAQAFTIDTGTN 241 Query: 295 LLVGPVDEVKELQK-AIGAVPLIQGEYMIPCEKV----SSLPIITFKLGGQNYEL----H 345 + P +++ K A+ Q Y +PC K ++ ++ K G + + Sbjct: 242 FFIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVP 301 Query: 346 PEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 K +L V ++G+T C+ + P G +I+G++F+ + V+D NR+GFA A Sbjct: 302 ISKMLLPVDKSGET-CMF-----IVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAPLA 355 Query: 406 T 406 + Sbjct: 356 S 356 >2H6T-A nrPDB Length = 340 Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats. Identities = 85/353 (24%), Positives = 140/353 (39%), Gaps = 36/353 (10%) Query: 65 EPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIH--CKLLD----IACW 118 + V L N Y +I +G+ Q TVV DTGSS+LWVP C+ C Sbjct: 1 QTVPVKLINEQ-VSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCK 59 Query: 119 VHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 Y+ SS+ + F I YG G+ S G +DT+ GGI + KQ F + Sbjct: 60 NEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIG------FGGISITKQQFADV 113 Query: 178 TKQPGVVFIAAKFDGILGMGYPFISV-NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQP 236 T + GILG+GY V L Q ++ KN +S YLN Sbjct: 114 T-------STSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQA--T 164 Query: 237 GGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLL 296 G+++ GG D+ Y G L L VT ++H++ ++V + + ++D+GT++ Sbjct: 165 SGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSI--NADVDVLLDSGTTIT 222 Query: 297 VGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVSSLPIITFKLGGQNYELHPEKYILK 352 ++ A Y++ C S+ F + + ++ Sbjct: 223 YLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSV-DFAFDKNAK-ISVPASEFTAP 280 Query: 353 VSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 + + + + + ILGD F+ Y V+D + N + A+ Sbjct: 281 LYTEDGQV----YDQCQLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVK 329 >4B1C-A nrPDB Length = 375 Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats. Identities = 93/353 (26%), Positives = 149/353 (42%), Gaps = 48/353 (13%) Query: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSF 138 YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 73 Query: 139 DIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGY 198 + Y G G L D VS+P + + V T+ + ++GILG+ Y Sbjct: 74 YVPYTQGKWEGELGTDLVSIPHGPN---VTVRAN-IAAITESDKFFINGSNWEGILGLAY 129 Query: 199 PFISV--NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSY 256 I+ + + P FD+L+KQ V N+FS L + GG D Y G L Y Sbjct: 130 AEIARPDDSLEPFFDSLVKQTHV-PNLFSLQLCGGGSMIIGGI------DHSLYTGSLWY 182 Query: 257 LNVTRKAYWQVHMDQLEVGSE--LTLCK--GGCEAIVDTGTSLLVGPVDEVKELQKAIGA 312 + R+ Y++V + ++E+ + CK ++IVD+GT+ L P + K+I A Sbjct: 183 TPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKA 242 Query: 313 VPLIQG-------EYMIPCEKVSS-----LPIITFKLGGQ------NYELHPEKYILKVS 354 + + C + + P+I+ L G+ + P++Y+ V Sbjct: 243 ASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVE 302 Query: 355 QAGKTI--CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 + C + S ++G V + +Y VFDR R+GFA +A Sbjct: 303 DVATSQDDCYKFAISQ-----SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 350 >3PI0-A nrPDB Length = 330 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 87/352 (24%), Positives = 136/352 (38%), Gaps = 31/352 (8%) Query: 58 QSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIAC 117 + T P+ + LD Y + IGTP Q + FDTGSS+LWV S ++ Sbjct: 1 STGSATTTPI-----DSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDG 55 Query: 118 WVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 + + ++ + T + S SG + DTVSV GG+ V Q A Sbjct: 56 QTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSV------GGLTVTGQAVESA 109 Query: 178 TKQPGVVFIAAKFDGILGMGYPFISV---NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTG 234 K + DG+LG+ + ++ + FDN ++ +F+ L Sbjct: 110 KKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKAS--LDSPVFTADLGYHAP- 166 Query: 235 QPGGELMLGGTDSRYYHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGT 293 G G D+ Y G ++Y V T++ +W+ VGS T + I DTGT Sbjct: 167 ---GTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSG-TFKSTSIDGIADTGT 222 Query: 294 SLLVGPVDEVKELQKAIGAVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYIL 351 +LL P V + G Y+ PC ++LP TF +G + + Sbjct: 223 TLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVIPGDYIDF 280 Query: 352 KVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDRE-YNRVGFA 402 G + C G + I GDV + + VF+ +GFA Sbjct: 281 GPISTGSSSCFGGIQS----SAGIGINIFGDVALKAAFVVFNGATTPTLGFA 328 >1IBQ-A nrPDB Length = 325 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 93/339 (27%), Positives = 139/339 (41%), Gaps = 35/339 (10%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNG 135 D +Y + +G + FDTGS++LWV S + H Y S+T + G Sbjct: 13 DEEYLTPVTVG--KSTLHLDFDTGSADLWVFSDELPSSEQTG--HDLYTPSSSATKLS-G 67 Query: 136 TSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 S+DI YG GS SG + +DTV+V GG+ KQ A+K DG+L Sbjct: 68 YSWDISYGDGSSASGDVYRDTVTV------GGVTTNKQAVEAASKISSEFVQDTANDGLL 121 Query: 195 GMGYPFISVNKVLP-----VFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRY 249 G+ + S+N V P FD + Q ++ +F+ L D G G D Sbjct: 122 GLAF--SSINTVQPKAQTTFFDTVKSQ--LDSPLFAVQLKHDAP----GVYDFGYIDDSK 173 Query: 250 YHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK 308 Y G ++Y + + + YW D + + G AI DTGT+L++ + V + Sbjct: 174 YTGSITYTDADSSQGYWGFSTDGYS-IGDGSSSSSGFSAIADTGTTLILLDDEIVSAYYE 232 Query: 309 AIGAVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 366 + G Y+ C LP T +G + + G + C G Sbjct: 233 QVSGAQESYEAGGYVFSCST--DLPDFTVVIGDYKAVVPGKYINYAPVSTGSSTCYGGIQ 290 Query: 367 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 L ILGDVF+ Y VF+ E ++GFA A Sbjct: 291 SN----SGLGLSILGDVFLKSQYVVFNSEGPKLGFAAQA 325 >1PPK-E nrPDB Length = 323 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 86/336 (25%), Positives = 132/336 (39%), Gaps = 32/336 (9%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNG 135 D +Y + IG + FDTGS++LWV S + H YN + + G Sbjct: 14 DEEYITPVTIG--GTTLNLNFDTGSADLWVFSTELPASQQSG--HSVYNPSATGKELS-G 68 Query: 136 TSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 ++ I YG GS SG + D+V+V GG+ Q A + DG+L Sbjct: 69 YTWSISYGDGSSASGNVFTDSVTV------GGVTAHGQAVQAAQQISAQFQQDTNNDGLL 122 Query: 195 GMGYPFISV--NKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHG 252 G+ + I+ + F + +K L + +F+ L G G DS Y G Sbjct: 123 GLAFSSINTVQPQSQTTFFDTVKSSL-AQPLFAVALKHQQP----GVYDFGFIDSSKYTG 177 Query: 253 ELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIG 311 L+Y V + +W ++D GS+ G I DTGT+LL+ V + + Sbjct: 178 SLTYTGVDNSQGFWSFNVDSYTAGSQS---GDGFSGIADTGTTLLLLDDSVVSQYYSQVS 234 Query: 312 AVPLIQ--GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMD 369 G Y+ C +LP + + G + P I + CL G Sbjct: 235 GAQQDSNAGGYVFDCST--NLPDFSVSISGYTATV-PGSLINYGPSGDGSTCLGGIQSN- 290 Query: 370 IPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 I GD+F+ Y VFD + ++GFA A Sbjct: 291 ---SGIGFSIFGDIFLKSQYVVFDSDGPQLGFAPQA 323 >3EMY-A nrPDB Length = 329 Score = 214 bits (546), Expect = 5e-56, Method: Composition-based stats. Identities = 76/346 (21%), Positives = 127/346 (36%), Gaps = 25/346 (7%) Query: 64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKY 123 + D++Y + IGTP Q + FDTGSS+LWV S + Sbjct: 2 TGSAPNHPSDSADSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPKSSATGHAIYTP 61 Query: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGV 183 + +S V + + S SG + D V++ GG V Q AT+ Sbjct: 62 SKSSTSKKVSGASWSISYGDGSSSSGDVYTDKVTI------GGFSVNTQGVESATRVSTE 115 Query: 184 VFIAAKFDGILGMGYPFISVNKVLP-----VFDNLMKQKLVEKNIFSFYLNRDPTGQPGG 238 G++G+ + S N+V P F N + + +F+ L G Sbjct: 116 FVQDTVISGLVGLAFD--SGNQVRPHPQKTWFSNAASS--LAEPLFTADLRHGQ----NG 167 Query: 239 ELMLGGTDSRYYHGELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLV 297 G D+ G ++Y V + +W+ VG L + + I DTGT+LL+ Sbjct: 168 SYNFGYIDTSVAKGPVAYTPVDNSQGFWEFTASGYSVGGG-KLNRNSIDGIADTGTTLLL 226 Query: 298 GPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAG 357 + V + + + + + LP +F +G + + L + G Sbjct: 227 LDDNVVDAYYANVQSAQYDNQQEGVVFDCDEDLPSFSFGVGSSTITIPGDLLNLTPLEEG 286 Query: 358 KTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAK 403 + C G + I GDV + VFD R+G+A+ Sbjct: 287 SSTCFGGLQS----SSGIGINIFGDVALKAALVVFDLGNERLGWAQ 328 >3OAD-B nrPDB Length = 176 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 70/170 (41%), Positives = 104/170 (61%), Gaps = 1/170 (0%) Query: 235 QPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTS 294 GG+++LGG+D ++Y G Y+N+ + WQ+ M + VGS LC+ GC A+VDTG S Sbjct: 1 SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGAS 60 Query: 295 LLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVS 354 + G +++L +A+GA + +Y++ C + +LP I+F LGG+ Y L Y+ + S Sbjct: 61 YISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQES 119 Query: 355 QAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404 + K +C MDIPPP+GP W LG FI +YT FDR NR+GFA A Sbjct: 120 YSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 169 >1IZE-A nrPDB Length = 323 Score = 210 bits (535), Expect = 7e-55, Method: Composition-based stats. Identities = 90/337 (26%), Positives = 136/337 (40%), Gaps = 34/337 (10%) Query: 76 DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNG 135 D +Y ++ +G + FDTGS++LWV S + + H Y + SS +G Sbjct: 14 DEEYITQVTVGDD--TLGLDFDTGSADLWVFSSQTPSSERSG---HDYYTPGSSAQKIDG 68 Query: 136 TSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGIL 194 ++ I YG GS SG + +D V+V GG+ + Q A K DG+L Sbjct: 69 ATWSISYGDGSSASGDVYKDKVTV------GGVSYDSQAVESAEKVSSEFTQDTANDGLL 122 Query: 195 GMGYPFISVNKVLP---VFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYH 251 G+ + I+ + P FDN+ + + IF+ L + G G TDS Y Sbjct: 123 GLAFSSINTVQPTPQKTFFDNVKSS--LSEPIFAVALKHNAP----GVYDFGYTDSSKYT 176 Query: 252 GELSYLNV-TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAI 310 G ++Y +V + +W D I DTGT+LL+ V + + Sbjct: 177 GSITYTDVDNSQGFWGFTADGYS--IGSDSSSDSITGIADTGTTLLLLDDSIVDAYYEQV 234 Query: 311 GAV--PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368 QG Y+ P +SLP + +G + P +YI + G G Sbjct: 235 NGASYDSSQGGYVFP--SSASLPDFSVTIGDYTATV-PGEYI-SFADVGNGQTFGGIQSN 290 Query: 369 DIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 405 I GDVF+ Y VFD R+GFA A Sbjct: 291 ----SGIGFSIFGDVFLKSQYVVFDASGPRLGFAAQA 323 >3O9L-A nrPDB Length = 166 Score = 205 bits (522), Expect = 3e-53, Method: Composition-based stats. Identities = 83/172 (48%), Positives = 117/172 (68%), Gaps = 7/172 (4%) Query: 60 SPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWV 119 S +L NY+D QYYGEIGIGTPPQ F VVFDTGSSN+WVPS C L AC Sbjct: 1 LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVY 60 Query: 120 HHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATK 179 H +++ SS+Y NGT + Y +G++SG+LSQD ++V GGI V Q+FGE T+ Sbjct: 61 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITV------GGITVT-QMFGEVTE 113 Query: 180 QPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRD 231 P + F+ A+FDG++GMG+ ++ +V P+FDN++ Q ++++++FSFY NRD Sbjct: 114 MPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 165 >1WKR-A nrPDB Length = 340 Score = 192 bits (487), Expect = 3e-49, Method: Composition-based stats. Identities = 99/355 (27%), Positives = 151/355 (42%), Gaps = 50/355 (14%) Query: 68 SELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDK 127 S N L Y +G+G+P ++++ DTGSSN W+ + + K Sbjct: 4 SVPATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLGADKSYV--------------K 48 Query: 128 SSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIA 187 +ST + YGSGS SG DTV+ LG + + KQ G A++ G + Sbjct: 49 TSTSSATSDKVSVTYGSGSFSGTEYTDTVT------LGSLTIPKQSIGVASRDSGFDGV- 101 Query: 188 AKFDGILGMGYPFISVNKVLP--------VFDNLMKQKLVEKNIFSFYL-NRDPTGQPGG 238 DGILG+G ++V + P V DNL Q + N+ + G Sbjct: 102 ---DGILGVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNG 158 Query: 239 ELMLGGTDSRYYHGELSYLNVTR----KAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTS 294 EL G TDS Y G ++Y +T AYW ++ + GS ++ IVDTGT+ Sbjct: 159 ELTFGATDSSKYTGSITYTPITSTSPASAYWGIN-QSIRYGSSTSILS-STAGIVDTGTT 216 Query: 295 LLVGPVDEVKELQKAIGAVPLIQ-GEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILK- 352 L + D + +KA GAV G + + ++L + F +GGQ +EL I Sbjct: 217 LTLIASDAFAKYKKATGAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPR 276 Query: 353 ------VSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGF 401 A + G +G D G +I G F+ +Y+V+D R+G Sbjct: 277 NLNTAIGGSASSVYLIVGDLGSD--SGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >4ZL4-A nrPDB Length = 444 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 94/426 (22%), Positives = 146/426 (34%), Gaps = 125/426 (29%) Query: 77 AQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH--HKYNSDKSSTY--- 131 A Y+ +I IGTP Q +++ DTGSS+L P CK C VH + +N + S T Sbjct: 28 AYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCK----NCGVHMENPFNLNNSKTSSIL 83 Query: 132 -------------VKNGTSFDIHYGSGS-LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEA 177 VK + Y GS +SG+ D VSV +V + Sbjct: 84 YCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSV---VSYNNERVTFRKLMGC 140 Query: 178 TKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVE-KNIFSFYLNRDPTGQP 236 +F+ + G+LGM +S + +P F NL+ + K +F+ ++ + Sbjct: 141 HMHEESLFLYQQATGVLGM---SLSKPQGIPTFVNLLFDNAPQLKQVFTICIS-----EN 192 Query: 237 GGELMLGGTDSRYY-----------HGE-----------------------LSYLNVTRK 262 GGEL+ GG D Y G + + NVTRK Sbjct: 193 GGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKVVWENVTRK 252 Query: 263 AYWQVHMDQLEV-GSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQK--AIGAVPLIQGE 319 Y+ + + L++ G+ + G E +VD+G++ P D +L I + + Sbjct: 253 YYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLNYFFDILCIQDMNNA 312 Query: 320 YMIP------------------------------------------CEKV-SSLPIITFK 336 Y + C K LP + Sbjct: 313 YDVNKRLKMTNESFNNPLVQFDDFRKSLKSIIAKENMCVKIVDGVQCWKYLEGLPDLFVT 372 Query: 337 L-GGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDRE 395 L + P Y+ K F I ILG F +FD + Sbjct: 373 LSNNYKMKWQPHSYLYKKES---------FWCKGIEKQVNNKPILGLTFFKNRQVIFDIQ 423 Query: 396 YNRVGF 401 NR+GF Sbjct: 424 KNRIGF 429 >4OD9-A nrPDB Length = 103 Score = 157 bits (398), Expect = 6e-39, Method: Composition-based stats. Identities = 92/102 (90%), Positives = 98/102 (96%) Query: 61 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 120 T+ P+ E+LKNY+DAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW+H Sbjct: 2 AVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIH 61 Query: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKS 162 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPC+S Sbjct: 62 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 103 >1B5F-B nrPDB Length = 87 Score = 112 bits (281), Expect = 3e-25, Method: Composition-based stats. Identities = 44/87 (50%), Positives = 58/87 (66%), Gaps = 1/87 (1%) Query: 319 EYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLW 378 E + C +SS+P ++F +GG+ + L PE+YILKV + T C+SGF MD GPLW Sbjct: 2 ELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPLW 60 Query: 379 ILGDVFIGCYYTVFDREYNRVGFAKAA 405 ILGDVF+ Y+TVFD VGFA+AA Sbjct: 61 ILGDVFMRPYHTVFDYGNLLVGFAEAA 87 >3AUP-A nrPDB Length = 403 Score = 56.2 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 62/380 (16%), Positives = 122/380 (32%), Gaps = 85/380 (22%) Query: 87 TPPQCFTVVFDTGSSNLWVP----------------SIHCKLLDI----ACWVHHKYNSD 126 TP V+ D ++LWV S C + +C + Sbjct: 31 TPLMQVPVLVDLNGNHLWVNCEQQYSSKTYQAPFCHSTQCSRANTHQCLSCPAASRPGCH 90 Query: 127 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI 186 K++ + + G G L +D +++ Q G P +F Sbjct: 91 KNTCGLMSTNPITQQTG----LGELGEDVLAIHATQG------STQQLGPLVTVPQFLFS 140 Query: 187 AAK-----------FDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ 235 A G+ G+G+ IS+ L L +Q F+ L+R PT + Sbjct: 141 CAPSFLVQKGLPRNTQGVAGLGHAPISLPNQLASHFGLQRQ-------FTTCLSRYPTSK 193 Query: 236 PGGELMLGGTDSR---------YYHGELSYLNVTRKAYWQVHMDQLEVG----------S 276 G ++ G + ++ + L +T + + V ++ + + S Sbjct: 194 --GAIIFGDAPNNMRQFQNQDIFHDLAFTPLTITLQGEYNVRVNSIRINQHSVFPLNKIS 251 Query: 277 ELTLCKGGCEAIVDTGTSLLVGPVD--------EVKELQKAIGAVPLIQGEYMIPCEKVS 328 + ++ T T +V ++L K + K++ Sbjct: 252 STIVGSTSGGTMISTSTPHMVLQQSVYQAFTQVFAQQLPKQAQVKSVAPFGLCFNSNKIN 311 Query: 329 SLPIITFKL---GGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFI 385 + P + + G + + E ++ QA + G M + P + LG + Sbjct: 312 AYPSVDLVMDKPNGPVWRISGEDLMV---QAQPGVTCLGVMNGGMQPRAEIT--LGARQL 366 Query: 386 GCYYTVFDREYNRVGFAKAA 405 VFD +RVGF+ ++ Sbjct: 367 EENLVVFDLARSRVGFSTSS 386 >4PPH-A nrPDB Length = 417 Score = 54.3 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 66/376 (17%), Positives = 113/376 (30%), Gaps = 76/376 (20%) Query: 87 TPPQCFTVVFDTGSSNLWVPSIHCKLLDIA----CW--------VHHKYNSDKSSTYVKN 134 TP ++ D +LWV C H + S+T Sbjct: 36 TPLMQVPLLLDLNGKHLWVTCSQHYSSSTYQAPFCHSTQCSRANTHQCFTCTDSTTTRPG 95 Query: 135 ------GTSFDIHYGSGSLSGYLSQDTVSV--PCKSDLGG-IKVEKQIFGEATKQPGVVF 185 G S G L+QD +++ S LG +KV + +F A Sbjct: 96 CHNNTCGLLSSNPVTQESGLGELAQDVLAIHSTHGSKLGPMVKVPQFLFSCAPSFLAQKG 155 Query: 186 IAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGT 245 + G LG+G IS+ L L +Q FS L+R G ++ G Sbjct: 156 LPNNVQGALGLGQAPISLQNQLFSHFGLKRQ-------FSVCLSRY--STSNGAILFGDI 206 Query: 246 ----DSRYYHGE------LSYLNVT--RKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGT 293 ++ Y H L Y +T ++ + + ++ + V L + I + T Sbjct: 207 NDPNNNNYIHNSLDVLHDLVYTPLTISKQGEYFIQVNAIRVNKHLVIPTKNP-FISPSST 265 Query: 294 S-------------------------LLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVS 328 S V + K + K+S Sbjct: 266 SYHGSGEIGGALITTTHPYTVLSHSIFEVFTQVFANNMPKQAQVKAVGPFGLCYDSRKIS 325 Query: 329 SLP---IITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFI 385 + + + E ++++ + GF+ + +G LG + Sbjct: 326 GGAPSVDLILDKNDAVWRISSENFMVQAQDGVSCL---GFVDGGVHARAGIA--LGAHHL 380 Query: 386 GCYYTVFDREYNRVGF 401 VFD E +RVGF Sbjct: 381 EENLVVFDLERSRVGF 396 >1T6G-A nrPDB Length = 381 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 44/270 (16%), Positives = 74/270 (27%), Gaps = 49/270 (18%) Query: 177 ATKQPGVVFIAAKFDGILGMGYPF---ISVNKVLPVFDNLMKQKLVEK----------NI 223 A G ++ G+L P S+ + L L N Sbjct: 104 ANTTDGSKPVSKVNVGVLAACAPSKLLASLPRGSTGVAGLANSGLALPAQVASAQKVANR 163 Query: 224 FSFYLNRDPTGQPGGELMLGG--TDSRYYHGELSYLNVTRKA---YWQVHMDQLEVGSEL 278 F L G + GG + + Y + K + + VG Sbjct: 164 FLLCL----PTGGPGVAIFGGGPVPWPQFTQSMPYTPLVTKGGSPAHYISARSIVVGDTR 219 Query: 279 TLCKGGCEA----------------------IVDTGTSLLVGPVDEVKELQKAIGAVPLI 316 G A ++D T L + +A+ AV Sbjct: 220 VPVPEGALATGGVMLSTRLPYVLLRPDVYRPLMDAFTKALAAQHANGAPVARAVEAVAPF 279 Query: 317 QGEYMIPC--EKVSS--LPIITFKL-GGQNYELHPEKYILKVSQAGKTICLSGFMGMDIP 371 Y + +P + L GG ++ + + ++ V Q + G+ Sbjct: 280 GVCYDTKTLGNNLGGYAVPNVQLGLDGGSDWTMTGKNSMVDVKQGTACVAFVEMKGVAAG 339 Query: 372 PPSGPLWILGDVFIGCYYTVFDREYNRVGF 401 P ILG + + FD E R+GF Sbjct: 340 DGRAPAVILGGAQMEDFVLDFDMEKKRLGF 369 >3HD8-A nrPDB Length = 389 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 37/242 (15%), Positives = 70/242 (28%), Gaps = 43/242 (17%) Query: 192 GILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGG--TDSRY 249 G+ G+ +++ + N F L G + GG Sbjct: 141 GVAGLAGSGLALPSQ-------VASAQKVPNKFLLCL----PTGGPGVAIFGGGPLPWPQ 189 Query: 250 YHGELSYLNVTRKA---YWQVHMDQLEVGSELTLCKGGCEA------------------- 287 + + Y + K + ++V + A Sbjct: 190 FTQSMDYTPLVAKGGSPAHYISARSIKVENTRVPISERALATGGVMLSTRLPYVLLRRDV 249 Query: 288 ---IVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPC--EKVSS--LPIITFKL-GG 339 +VD T L + +A+ V + Y +P + +L GG Sbjct: 250 YRPLVDAFTKALAAQPANGAPVARAVKPVAPFELCYDTKTLGNNPGGYWVPNVLLELDGG 309 Query: 340 QNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRV 399 ++ + + ++ V + G+D S P ILG + + FD E R+ Sbjct: 310 SDWAMTGKNSMVDVKPGTACVAFVEMKGVDAGDGSAPAVILGGAQMEDFVLDFDMEKKRL 369 Query: 400 GF 401 GF Sbjct: 370 GF 371 >4Y8P-I nrPDB Length = 205 Score = 35.8 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 42/112 (37%), Gaps = 12/112 (10%) Query: 144 SGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISV 203 G + +D V++ C LG Q G + K + F GI G+ ++ Sbjct: 9 GGIVVAMTGKDCVAIACDLRLGS-----QSLGVSNKFEKIFHYGHVFLGITGLATDVTTL 63 Query: 204 NK---VLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLG----GTDSR 248 N+ L +++ +E F+ ++ + G +G G +S+ Sbjct: 64 NEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSK 115 >3Q31-A nrPDB Length = 244 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 48/145 (33%), Gaps = 19/145 (13%) Query: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIF-GEATKQPGVVFIA 187 S G + +GSL+ T++ V ++ F E A Sbjct: 66 SKLENLGFGLQVTLTNGSLTANSKTYTLAQFHFHTPSEHHVNEEHFPMEVHFV---FQTA 122 Query: 188 AKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDS 247 AK ++G + V +P+FD++ ++ + T G+L GG Sbjct: 123 AKETAVVGFFFQLSEVGDSVPLFDSVFA--PIDN------IPDAGTSTTTGQLDFGGLLD 174 Query: 248 RY-------YHGELSYLNVTRKAYW 265 + Y G L+ T + W Sbjct: 175 HFNRHGVYQYTGSLTTPPCTEEVMW 199 >2BKL-A nrPDB Length = 695 Score = 33.1 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 29/85 (34%), Gaps = 12/85 (14%) Query: 75 LDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST---- 130 LD YY TP Q + TG S LW + + V + + K T Sbjct: 374 LDDAYYVFTSFTTPRQIYKTSVSTGKSELW-AKVDVPMNPEQYQVEQVFYASKDGTKVPM 432 Query: 131 -------YVKNGTSFDIHYGSGSLS 148 ++G + + YG G + Sbjct: 433 FVVHRKDLKRDGNAPTLLYGYGGFN 457 >3OS6-A nrPDB Length = 399 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 17/46 (36%) Query: 246 DSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDT 291 D ++ G L + ++ W V + EV G + ++ Sbjct: 324 DREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAES 369 >5GJQ-a nrPDB Length = 239 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 15/97 (15%) Query: 222 NIFSFYLN------RDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVG 275 ++S + G G + G D+ Y G +T++ Q + L + Sbjct: 144 QVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREG------MTKEECLQFTANALALA 197 Query: 276 SELTLCKGGC---EAIVDTGTSLLVGPVDEVKELQKA 309 E GG AI ++G V D++ + A Sbjct: 198 MERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVA 234 >5LEZ-N nrPDB Length = 205 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 15/97 (15%) Query: 222 NIFSFYLN------RDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVG 275 ++S + G G + G D+ Y G +T++ Q + L + Sbjct: 110 QVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREG------MTKEECLQFTANALALA 163 Query: 276 SELTLCKGGC---EAIVDTGTSLLVGPVDEVKELQKA 309 E GG AI ++G V D++ + A Sbjct: 164 MERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVA 200 >3VLB-A nrPDB Length = 413 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 57/398 (14%), Positives = 114/398 (28%), Gaps = 85/398 (21%) Query: 72 KNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPS----------------IHCKLL-- 113 K+ QY I TP +V D G LWV C L Sbjct: 15 KDASTLQYVTTINQRTPLVSENLVVDLGGRFLWVDCDQNYVSSTYRPVRCRTSQCSLSGS 74 Query: 114 --DIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPC--KSDLGGIKV 169 C+ + + ++ V I+ +G G +++D VSV S G + Sbjct: 75 IACGDCFNGPRPGCNNNTCGVFPENPV-INTATG---GEVAEDVVSVESTDGSSSGRVVT 130 Query: 170 EKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLN 229 + + +A+ G+ G+G I++ + ++ F+ L+ Sbjct: 131 VPRFIFSCAPTSLLQNLASGVVGMAGLGRTRIALPSQFASAFSFKRK-------FAMCLS 183 Query: 230 RDPTGQPGGELMLGGTDSRYY-------HGELSYLNVTR--------------KAYWQVH 268 + ++ G D + L+Y + + + Sbjct: 184 --GSTSSNSVIIFGN-DPYTFLPNIIVSDKTLTYTPLLTNPVSTSATSTQGEPSVEYFIG 240 Query: 269 MDQLEVGSELTLCKGGCEAIVDTG----------------TSLLVGPV------DEVKEL 306 + +++ S++ +I G TS+ + + Sbjct: 241 VKSIKINSKIVALNTSLLSISSAGLGGTKISTINPYTVLETSIYKAVTEAFIKESAARNI 300 Query: 307 QKAIGAVPL---IQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLS 363 + P + ++ S+P I L ++ V +CL Sbjct: 301 TRVASVAPFGACFSTDNILSTRLGPSVPSIDLVLQSESVVWTITGSNSMVYINDNVVCLG 360 Query: 364 GFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGF 401 +D ++G + FD +RVGF Sbjct: 361 ---VVDGGSNLRTSIVIGGHQLEDNLVQFDLATSRVGF 395 >2D81-A nrPDB Length = 318 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 28/88 (31%), Gaps = 1/88 (1%) Query: 291 TGTSLLVGPVDEVKELQKAIGAVPLIQG-EYMIPCEKVSSLPIITFKLGGQNYELHPEKY 349 TG+S + + +L+ +G Y+ V + P G + L Y Sbjct: 97 TGSSDTTVGPNVMNQLKAQLGNFDNSANVSYVTTTGAVHTFPTDFNGAGDNSCSLSTSPY 156 Query: 350 ILKVSQAGKTICLSGFMGMDIPPPSGPL 377 I + G L G +G L Sbjct: 157 ISNCNYDGAGAALKWIYGSLNARNTGTL 184 >1IGA-A nrPDB Length = 475 Score = 28.1 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 88 PPQCFTVVFDTGSSNLWVPSIHC-KLLDIACWVHHKYNSDK 127 P Q + T SS L +P+ C + C V H N + Sbjct: 177 PSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQ 217 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.134 0.377 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,498,325 Number of Sequences: 36641 Number of extensions: 684707 Number of successful extensions: 2347 Number of sequences better than 10.0: 73 Number of HSP's better than 10.0 without gapping: 120 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1705 Number of HSP's gapped (non-prelim): 150 length of query: 407 length of database: 10,336,785 effective HSP length: 99 effective length of query: 308 effective length of database: 6,709,326 effective search space: 2066472408 effective search space used: 2066472408 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)