BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24182 (449 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3JZF-A nrPDB 924 0.0 4RZQ-A nrPDB 750 0.0 2C00-A nrPDB 672 0.0 2VPQ-A nrPDB 472 e-133 1ULZ-A nrPDB 452 e-127 3OUU-A nrPDB 439 e-123 2DZD-A nrPDB 400 e-112 3U9T-A nrPDB 398 e-111 3N6R-A nrPDB 394 e-110 5MLK-A nrPDB 342 3e-94 5H80-A nrPDB 284 5e-77 5KS8-A nrPDB 260 9e-70 2YL2-A nrPDB 250 7e-67 3JRW-A nrPDB 243 1e-64 1W93-A nrPDB 233 1e-61 2CQY-A nrPDB 72 4e-13 2YW2-A nrPDB 55 4e-08 3VPD-A nrPDB 47 1e-05 3AW8-A nrPDB 46 3e-05 3ORR-A nrPDB 45 8e-05 1UC8-A nrPDB 43 3e-04 4C5A-A nrPDB 42 4e-04 2XD4-A nrPDB 42 7e-04 2YS6-A nrPDB 40 0.002 2R84-A nrPDB 39 0.004 3AX6-A nrPDB 39 0.005 4WD3-A nrPDB 37 0.013 3QFF-A nrPDB 37 0.018 2FB9-A nrPDB 36 0.026 1E4E-B nrPDB 35 0.055 2IP4-A nrPDB 35 0.064 1EZ1-A nrPDB 34 0.11 5D8D-A nrPDB 34 0.17 2CZG-A nrPDB 33 0.17 5VEV-A nrPDB 33 0.36 3MJF-A nrPDB 32 0.40 2I87-A nrPDB 32 0.68 4HGN-A nrPDB 32 0.74 3K3P-A nrPDB 31 1.0 1VKZ-A nrPDB 30 1.7 5BPF-A nrPDB 30 1.7 1GSO-A nrPDB 30 2.4 3R5X-A nrPDB 30 2.6 2QK4-A nrPDB 30 3.1 3LP8-A nrPDB 29 3.2 3VOT-A nrPDB 29 4.3 >3JZF-A nrPDB Length = 486 Score = 924 bits (2388), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/449 (100%), Positives = 449/449 (100%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY Sbjct: 22 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 81 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI Sbjct: 82 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 141 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ Sbjct: 142 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 201 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV Sbjct: 202 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 261 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT Sbjct: 262 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 321 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP Sbjct: 322 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 381 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL Sbjct: 382 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 441 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQEK 449 QIRIMNDENFQHGGTNIHYLEKKLGLQEK Sbjct: 442 QIRIMNDENFQHGGTNIHYLEKKLGLQEK 470 >4RZQ-A nrPDB Length = 468 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/448 (82%), Positives = 407/448 (90%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 ML+K+VIANRGEIALRILRACKELGIKTVAVHS+ADRDLKHVLLADET+CIGPAPS KSY Sbjct: 21 MLEKVVIANRGEIALRILRACKELGIKTVAVHSTADRDLKHVLLADETICIGPAPSAKSY 80 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LNIPAII+AAE+TGA AIHPGYGFLSENA+FAEQVERSGF FIGP A+ IRLMGDKVSAI Sbjct: 81 LNIPAIIAAAEVTGADAIHPGYGFLSENADFAEQVERSGFTFIGPTADVIRLMGDKVSAI 140 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AMKKAGVPCVPGSDGP+ +D+ KN+ IAKRIGYP+IIKASGGGGGRGMRVVR + L + Sbjct: 141 KAMKKAGVPCVPGSDGPVSNDIAKNKEIAKRIGYPIIIKASGGGGGRGMRVVRSEDALEE 200 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 SI+MT+AEAKAAF+NDMVYMEKYLENPRHVEIQVLAD GNA+YLAERDCSMQRRHQKVV Sbjct: 201 SIAMTKAEAKAAFNNDMVYMEKYLENPRHVEIQVLADTHGNAVYLAERDCSMQRRHQKVV 260 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGIT E+RR IG RCA ACV+IGYRGAGTFEFL+ENGEFYFIEMNTRIQVEHPVT Sbjct: 261 EEAPAPGITEEVRRDIGSRCANACVEIGYRGAGTFEFLYENGEFYFIEMNTRIQVEHPVT 320 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EMITGVDL+KEQLRIAAG P+S KQE++ V+GHA+ECRINAEDP TFLPSPGK+ H+P Sbjct: 321 EMITGVDLVKEQLRIAAGLPISFKQEDIKVKGHAMECRINAEDPKTFLPSPGKVNHLHSP 380 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GG GVRW+SH+Y GYTVPP+YDSMI KLI YG+ R+VAI RM+NAL E IIDGIKTN+ L Sbjct: 381 GGLGVRWDSHVYGGYTVPPHYDSMIAKLITYGDTREVAIRRMQNALSETIIDGIKTNIPL 440 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQE 448 I+ DENFQ GGTNIHYLEKKLG+ E Sbjct: 441 HELILEDENFQKGGTNIHYLEKKLGMNE 468 >2C00-A nrPDB Length = 464 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/448 (71%), Positives = 388/448 (86%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 ML+K++IANRGEIALRILRACKELGIKTVAVHS+ADR+L H+ LADE+VCIGPAP+ +SY Sbjct: 1 MLEKVLIANRGEIALRILRACKELGIKTVAVHSTADRELMHLSLADESVCIGPAPATQSY 60 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L IPAII+AAE+TGA AIHPGYGFL+ENA+FAEQ+ERSGF F+GP AE IRLMGDKVSA Sbjct: 61 LQIPAIIAAAEVTGATAIHPGYGFLAENADFAEQIERSGFTFVGPTAEVIRLMGDKVSAK 120 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AMK+AGVP VPGSDGPL +D + AIA+ +GYPVIIKA+GGGGGRGMRVV ++EL + Sbjct: 121 DAMKRAGVPTVPGSDGPLPEDEETALAIAREVGYPVIIKAAGGGGGRGMRVVYDESELIK 180 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 S +TR EA AAF N MVY+EK+L NPRHVE+QVL+DGQGNAI+L +RDCS+QRRHQKV+ Sbjct: 181 SAKLTRTEAGAAFGNPMVYLEKFLTNPRHVEVQVLSDGQGNAIHLGDRDCSLQRRHQKVI 240 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGI + R+ + RC +AC++IGYRGAGTFEFL+ENG FYFIEMNTR+QVEHPV+ Sbjct: 241 EEAPAPGIDEKARQEVFARCVQACIEIGYRGAGTFEFLYENGRFYFIEMNTRVQVEHPVS 300 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EM+TGVD++KE LRIA+G+ LSI+QE+V +RGHA+ECRINAEDP TF+PSPGK+ FHAP Sbjct: 301 EMVTGVDIVKEMLRIASGEKLSIRQEDVVIRGHALECRINAEDPKTFMPSPGKVKHFHAP 360 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GG GVR +SH+Y+GY+VPP YDS++GK+I YG +RD A+ARM+NAL ELI+DGIKTN +L Sbjct: 361 GGNGVRVDSHLYSGYSVPPNYDSLVGKVITYGADRDEALARMRNALDELIVDGIKTNTEL 420 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQE 448 ++ D F GG NIHYLEKKLG+ + Sbjct: 421 HKDLVRDAAFCKGGVNIHYLEKKLGMDK 448 >2VPQ-A nrPDB Length = 451 Score = 472 bits (1215), Expect = e-133, Method: Compositional matrix adjust. Identities = 237/444 (53%), Positives = 316/444 (71%), Gaps = 4/444 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + K++IANRGEIA+RI+RAC++LGI+TVA++S D+D H +ADE C+GP S SYL Sbjct: 1 MKKVLIANRGEIAVRIIRACRDLGIQTVAIYSEGDKDALHTQIADEAYCVGPTLSKDSYL 60 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 NIP I+S A TG +HPGYGFL+ENA+FAE E FIGP ++I+ MG K A A Sbjct: 61 NIPNILSIATSTGCDGVHPGYGFLAENADFAELCEACQLKFIGPSYQSIQKMGIKDVAKA 120 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M KA VP VPGSDG L D+ + + IAK+IGYPVIIKA+ GGGG+G+RV R + EL Sbjct: 121 EMIKANVPVVPGSDG-LMKDVSEAKKIAKKIGYPVIIKATAGGGGKGIRVARDEKELETG 179 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 MT EA+ AF N +YMEK++EN RH+EIQ++ D GN I+L ERDC++QRR QK+VE Sbjct: 180 FRMTEQEAQTAFGNGGLYMEKFIENFRHIEIQIVGDSYGNVIHLGERDCTIQRRMQKLVE 239 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE--NGEFYFIEMNTRIQVEHPV 299 EAP+P + E RR +G +A + Y AGT EF+++ + +FYF+EMNTRIQVEHPV Sbjct: 240 EAPSPILDDETRREMGNAAVRAAKAVNYENAGTIEFIYDLNDNKFYFMEMNTRIQVEHPV 299 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 TEM+TG+DL+K QL++A G L KQE++ + GHA+E RINAE+P F+PSPGKI ++ Sbjct: 300 TEMVTGIDLVKLQLQVAMGDVLPYKQEDIKLTGHAIEFRINAENPYKNFMPSPGKIEQYL 359 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 APGG+GVR ES Y YT+PPYYDSM+ KLI + RD AI AL E ++ GI T + Sbjct: 360 APGGYGVRIESACYTNYTIPPYYDSMVAKLIIHEPTRDEAIMAGIRALSEFVVLGIDTTI 419 Query: 419 DLQIRIMNDENFQHGGTNIHYLEK 442 I+++N++ F+ G N ++LE+ Sbjct: 420 PFHIKLLNNDIFRSGKFNTNFLEQ 443 >1ULZ-A nrPDB Length = 451 Score = 452 bits (1162), Expect = e-127, Method: Compositional matrix adjust. Identities = 235/444 (52%), Positives = 312/444 (70%), Gaps = 4/444 (0%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M++K+++ANRGEIA+RI+RACKELGI TVA+++ + +HV LADE IG P + +Y Sbjct: 1 MVNKVLVANRGEIAVRIIRACKELGIPTVAIYNEVESTARHVKLADEAYMIGTDP-LDTY 59 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LN II+ A GA AIHPGYGFL+ENA FA+ E +G FIGP + I LMGDK + Sbjct: 60 LNKQRIINLALEVGADAIHPGYGFLAENAEFAKMCEEAGITFIGPHWKVIELMGDKARSK 119 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 MKKAGVP VPGSDG L +++ +A+A+ IGYPV++KA+ GGGGRG+R+ R + EL + Sbjct: 120 EVMKKAGVPVVPGSDGVL-KSLEEAKALAREIGYPVLLKATAGGGGRGIRICRNEEELVK 178 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 + EA+ AF + +EK++ENP+H+E QVL D GN I+L ERDCS+QRR+QK+V Sbjct: 179 NYEQASREAEKAFGRGDLLLEKFIENPKHIEYQVLGDKHGNVIHLGERDCSIQRRNQKLV 238 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFEN-GEFYFIEMNTRIQVEHPV 299 E AP+ +TPE R Y G KA +IGY AGT EF+ + G YFIEMNTRIQVEHPV Sbjct: 239 EIAPSLILTPEKREYYGNIVTKAAKEIGYYNAGTMEFIADQEGNLYFIEMNTRIQVEHPV 298 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 +EM+TG+D++K Q++IAAG+PL+IKQE+V G+A+ECRINAEDP F PS I R++ Sbjct: 299 SEMVTGIDIVKWQIKIAAGEPLTIKQEDVKFNGYAIECRINAEDPKKNFAPSTRVIERYY 358 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 PGGFG+R E G+ V PYYDSMI KLI + D A+ RM+ AL+ I G+KT + Sbjct: 359 VPGGFGIRVEHAAARGFEVTPYYDSMIAKLITWAPTWDEAVERMRAALETYEITGVKTTI 418 Query: 419 DLQIRIMNDENFQHGGTNIHYLEK 442 L I IM +++F+ G YLE+ Sbjct: 419 PLLINIMKEKDFKAGKFTTKYLEE 442 >3OUU-A nrPDB Length = 446 Score = 439 bits (1129), Expect = e-123, Method: Compositional matrix adjust. Identities = 235/442 (53%), Positives = 311/442 (70%), Gaps = 3/442 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + I+IANRGEIALR LR KE+G K + V+S AD+D ++ AD ++CIG A S +SYL Sbjct: 6 IKSILIANRGEIALRALRTIKEMGKKAICVYSEADKDALYLKYADASICIGKARSSESYL 65 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 NIPAII+AAEI A AI PGYGFLSEN NF E + FIGP E + LM DK A Sbjct: 66 NIPAIIAAAEIAEADAIFPGYGFLSENQNFVEICAKHNIKFIGPSVEAMNLMSDKSKAKQ 125 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M++AGVP +PGSDG L + + +AK IGYPVI+KA+ GGGGRGMRVV + +L ++ Sbjct: 126 VMQRAGVPVIPGSDGALAG-AEAAKKLAKEIGYPVILKAAAGGGGRGMRVVENEKDLEKA 184 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 +EA AF + +YMEKY++NPRH+E+QV+ D GN I++ ERDCSMQRRHQK++E Sbjct: 185 YWSAESEAMTAFGDGTMYMEKYIQNPRHIEVQVIGDSFGNVIHVGERDCSMQRRHQKLIE 244 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPVT 300 E+PA + + R + E KA IGY GAGTFEFL + N +FYFIEMNTR+QVEH V+ Sbjct: 245 ESPAILLDEKTRTRLHETAIKAAKAIGYEGAGTFEFLVDKNLDFYFIEMNTRLQVEHCVS 304 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EM++G+D+I++ +++A G L QE + + GH++ECRI AED TFLPSPGKIT++ P Sbjct: 305 EMVSGIDIIEQMIKVAEGYALP-SQESIKLNGHSIECRITAEDSKTFLPSPGKITKYIPP 363 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 G VR ESH Y Y+VP YYDSMIGKL+ + E+R+ AIA+MK AL EL+I GIKT D Sbjct: 364 AGRNVRMESHCYQDYSVPAYYDSMIGKLVVWAEDRNKAIAKMKVALDELLISGIKTTKDF 423 Query: 421 QIRIMNDENFQHGGTNIHYLEK 442 + +M + +F + + +YL + Sbjct: 424 HLSMMENPDFINNNYDTNYLAR 445 >2DZD-A nrPDB Length = 461 Score = 400 bits (1027), Expect = e-112, Method: Compositional matrix adjust. Identities = 205/447 (45%), Positives = 290/447 (64%), Gaps = 10/447 (2%) Query: 4 KIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPS-VKSYLN 62 K+++ANRGEIA+R+ RAC ELGI+TVA++S D H ADE +G +++YL+ Sbjct: 8 KVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKKPIEAYLD 67 Query: 63 IPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAA 122 I II A+ AIHPGYGFLSEN FA++ G IFIGP + + GDKV A A Sbjct: 68 IEGIIEIAKAHDVDAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHA 127 Query: 123 MKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSI 182 AG+P +PGSDGP+ D ++ A A+ GYP+IIKA+ GGGGRGMR+VR +E+ ++ Sbjct: 128 AVNAGIPVIPGSDGPV-DGLEDVVAFAEAHGYPIIIKAALGGGGRGMRIVRSKSEVKEAF 186 Query: 183 SMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEE 242 ++EAKAAF +D VY+EK +ENP+H+E+Q+L D +GN ++L ERDCS+QRRHQKVVE Sbjct: 187 ERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRHQKVVEV 246 Query: 243 APAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEM 302 AP+ ++ ELR+ I E + +GY AGT EFL EFYFIE+N RIQVEH +TEM Sbjct: 247 APSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVEHTITEM 306 Query: 303 ITGVDLIKEQLRIAAGQPLSI------KQEEVHVRGHAVECRINAEDP-NTFLPSPGKIT 355 ITG+D+++ Q+ IA G L KQE++ + G+A++ R+ EDP N F+P GKI Sbjct: 307 ITGIDIVQSQILIADGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMPDTGKIM 366 Query: 356 RFHAPGGFGVRWES-HIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGI 414 + + GGFGVR ++ + + G + PYYDS++ KL + + A +M L+E I GI Sbjct: 367 AYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKLSTWALTFEQAARKMLRNLREFRIRGI 426 Query: 415 KTNVDLQIRIMNDENFQHGGTNIHYLE 441 KTN+ ++ F G + +++ Sbjct: 427 KTNIPFLENVVQHPKFLSGEYDTSFID 453 >3U9T-A nrPDB Length = 655 Score = 398 bits (1023), Expect = e-111, Method: Compositional matrix adjust. Identities = 225/432 (52%), Positives = 297/432 (68%), Gaps = 4/432 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + ++++ANRGEIA R++R+ + LGI +VAVHS DR +HV AD V +G A SYL Sbjct: 8 IQRLLVANRGEIACRVMRSARALGIGSVAVHSDIDRHARHVAEADIAVDLGGAKPADSYL 67 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 II+AA +GA AIHPGYGFLSENA+FA E +G +F+GP A I MG K +A A Sbjct: 68 RGDRIIAAALASGAQAIHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKA 127 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M++AGVP VPG G D++ R A RIGYPV++KA+ GGGG+GM+VV +AELA++ Sbjct: 128 LMEEAGVPLVPGYHGE-AQDLETFRREAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEA 186 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 +S + EAKAAF + + +EKYL PRHVEIQV AD G+ +YL ERDCS+QRRHQKVVE Sbjct: 187 LSSAQREAKAAFGDARMLVEKYLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVE 246 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVT 300 EAPAPG+ ELRR +GE +A IGY GAGT EFL E G+F+F+EMNTR+QVEHPVT Sbjct: 247 EAPAPGLGAELRRAMGEAAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNTRLQVEHPVT 306 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPN-TFLPSPGKITRF-H 358 E ITG+DL+ Q+R+A G+ L + QE+V + GHA+E R+ AEDP FLP+ G++ + Sbjct: 307 EAITGLDLVAWQIRVARGEALPLTQEQVPLNGHAIEVRLYAEDPEGDFLPASGRLMLYRE 366 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 A G G R +S + G V P+YD M+ KLI +GE R+ A R+ L E + G++TN+ Sbjct: 367 AAAGPGRRVDSGVREGDEVSPFYDPMLAKLIAWGETREEARQRLLAMLAETSVGGLRTNL 426 Query: 419 DLQIRIMNDENF 430 RI+ F Sbjct: 427 AFLRRILGHPAF 438 >3N6R-A nrPDB Length = 681 Score = 394 bits (1011), Expect = e-110, Method: Compositional matrix adjust. Identities = 209/465 (44%), Positives = 295/465 (63%), Gaps = 23/465 (4%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M +KI+IANRGEIA R+++ +++GI TVA++S AD+ HV +ADE V IGP P+ +SY Sbjct: 1 MFNKILIANRGEIACRVIKTARKMGISTVAIYSDADKQALHVQMADEAVHIGPPPANQSY 60 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 + I +++A TGA A+HPGYGFLSEN+ FAE +E G IF+GP I MGDK+++ Sbjct: 61 IVIDKVMAAIRATGAQAVHPGYGFLSENSKFAEALEAEGVIFVGPPKGAIEAMGDKITSK 120 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 ++A V VPG G L +D D+ I+ +IGYPV+IKAS GGGG+GMR+ D E + Sbjct: 121 KIAQEANVSTVPGYMG-LIEDADEAVKISNQIGYPVMIKASAGGGGKGMRIAWNDQEARE 179 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 ++ EA +F +D +++EK++ PRH+EIQVL D GN IYL ER+CS+QRR+QKVV Sbjct: 180 GFQSSKNEAANSFGDDRIFIEKFVTQPRHIEIQVLCDSHGNGIYLGERECSIQRRNQKVV 239 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPV 299 EEAP+P + RR +GE+ +GY AGT EF+ + FYF+EMNTR+QVEHPV Sbjct: 240 EEAPSPFLDEATRRAMGEQAVALAKAVGYASAGTVEFIVDGQKNFYFLEMNTRLQVEHPV 299 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 TE+ITGVDL+++ +R+AAG+PLSI Q +V + G A+E R+ AEDP FLPS G++TR+ Sbjct: 300 TELITGVDLVEQMIRVAAGEPLSITQGDVKLTGWAIENRLYAEDPYRGFLPSIGRLTRYR 359 Query: 359 AP--------------------GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVA 398 P G VR ++ +Y G + YYD MI KL + R A Sbjct: 360 PPAETAAGPLLVNGKWQGDAPSGEAAVRNDTGVYEGGEISMYYDPMIAKLCTWAPTRAAA 419 Query: 399 IARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKK 443 I M+ AL ++GI N+ +M+ F G ++ ++ Sbjct: 420 IEAMRIALDSFEVEGIGHNLPFLSAVMDHPKFISGDMTTAFIAEE 464 >5MLK-A nrPDB Length = 614 Score = 342 bits (876), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 196/431 (45%), Positives = 280/431 (64%), Gaps = 4/431 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + K+++ANRGEIA+R++RA ++ G+ +VAV++ D + HV LADE +G S +SYL Sbjct: 26 ISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFALGGQTSAESYL 85 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 + I+ AA +GA AIHPGYGFL+ENA+FA+ V +G I+IGP ++IR +GDKV+A Sbjct: 86 DFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARH 145 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 +A P VPG+ P+ D+ A A+ G P+ IKA+ GGGG+GM+V R E+ + Sbjct: 146 IAARAQAPLVPGTPDPV-KGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPEL 204 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 EA AAF Y+E+YL+ PRHVE QV+AD GN + RDCS+QRR+QK+VE Sbjct: 205 YESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQRRYQKLVE 264 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVT 300 EAPAP +T R+ I + + C + Y GAGT E+L ++G F+E+NTR+QVEHPVT Sbjct: 265 EAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVNTRLQVEHPVT 324 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPN-TFLPSPGKITRFHA 359 E G+DL+ +Q RIA G+ L I ++ RGHA+E RIN ED FLP+PG +T+FH Sbjct: 325 EETAGIDLVLQQFRIANGEKLDITEDPTP-RGHAIEFRINGEDAGRNFLPAPGPVTKFHP 383 Query: 360 PGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVD 419 P G GVR +S + G + +DSM+ KLI +G +R A+AR + AL E ++G+ T + Sbjct: 384 PSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFGVEGLATVIP 443 Query: 420 LQIRIMNDENF 430 +++D F Sbjct: 444 FHRAVVSDPAF 454 >5H80-A nrPDB Length = 494 Score = 284 bits (727), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 178/460 (38%), Positives = 266/460 (57%), Gaps = 23/460 (5%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M +++IANRGE+A+RI RA LG ++VAV++ D HV ADE V + +Y Sbjct: 31 MTPRVLIANRGEVAVRIERAVSALGWQSVAVYAPDDAGSLHVRRADEAVALS-GRGAAAY 89 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L+ A++ A+ A +HPGYGFLSENA+FA ++G +F+GP +T+ L GDK A Sbjct: 90 LDGAALLRVAQEHAATHVHPGYGFLSENADFARACAQAGLVFVGPDPDTLDLFGDKSRAR 149 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAK-RIGYPVIIKASGGGGGRGMRVVRGDAELA 179 ++ GVP +PG+DG +++ A + + G PV++KA GGGGRGMRVVR +LA Sbjct: 150 GLAQRLGVPVIPGTDG--ATTLEEAAAFMQAQGGAPVMLKACSGGGGRGMRVVRQAGDLA 207 Query: 180 QSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKV 239 + EA+ A +Y E+ +E RH+E+QV DGQ + +L ERDC++QRRHQK+ Sbjct: 208 AAFEQASREARLAVGQGDLYAERLIERARHIEVQVAGDGQ-SVTHLWERDCTVQRRHQKL 266 Query: 240 VEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHP 298 +E APAP + +R + + ++ YR GTFEFL G+FYFIE N R+QVEH Sbjct: 267 LEFAPAPHLPQAVRTALIGAALQLAQEVKYRCLGTFEFLVTPGGDFYFIEANPRLQVEHT 326 Query: 299 VTEMITGVDLIKEQLRIAAGQPLSI------KQEEVHVRGHAVECRINAE----DPNTFL 348 VTE G DL+ QLR+AAG+ L+ + G AV+ R+N E D + Sbjct: 327 VTEEWCGTDLVTAQLRLAAGETLTAVGLATQPADAAPPPGQAVQARVNMETLGADGQVHV 386 Query: 349 PSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIA----RMKN 404 G++ F PGG GVR ++ + G T P YD+++ K++ + RD A+ + Sbjct: 387 -GGGQVQTFTPPGGPGVRVDTFVTTGLTPSPQYDALLAKVVVH--RRDAALPGLLRQAAT 443 Query: 405 ALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKL 444 AL E I G+ TN+ +++ + QH + H+L+++L Sbjct: 444 ALSEFQIAGVSTNLAFLQALLHHPDVQHYELSTHWLDERL 483 >5KS8-A nrPDB Length = 405 Score = 260 bits (664), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 122/238 (51%), Positives = 168/238 (70%), Gaps = 2/238 (0%) Query: 206 NPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACV 265 NPRH+E+QVLAD GN I+L ERDCS+QRR+QK++E AP+P ++ R YIG KA Sbjct: 137 NPRHIEVQVLADSHGNVIHLFERDCSIQRRNQKLIEIAPSPQLSKAQREYIGNLAVKAAK 196 Query: 266 DIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIK 324 +GY+ AGT EFL + + FYF+EMNTR+QVEH VTE ITG+D+++EQ+R+A GQ L K Sbjct: 197 AVGYKNAGTVEFLLDSDNNFYFMEMNTRLQVEHTVTEQITGIDIVQEQIRVADGQRLQYK 256 Query: 325 QEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDS 383 Q EV RG A+E RINAEDP N FLPS GKITR++APGG G+R ++ +Y+GY +PPYYDS Sbjct: 257 QSEVQYRGFAMEFRINAEDPKNDFLPSFGKITRYYAPGGPGIRMDAAMYSGYVIPPYYDS 316 Query: 384 MIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLE 441 M KL + N + + R + AL + ++ G+KT + I+ +F++ N ++E Sbjct: 317 MCAKLTVWALNWESVVERGRRALNDTVVYGVKTTIPYYQEILKHPDFRNAIFNTSFVE 374 >2YL2-A nrPDB Length = 540 Score = 250 bits (639), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 163/504 (32%), Positives = 263/504 (52%), Gaps = 67/504 (13%) Query: 1 MLDKIVIANRGEIALRILRACK---------ELGIKTVAVHSSAD--RDLKHVLLADETV 49 +++K++IAN G A++ +R+ + E I+ V + + D + +++ +AD V Sbjct: 40 VIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYV 99 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAET 109 + P+ +Y N+ I+ A+ A+ G+G SEN E + ++G F+GP ++ Sbjct: 100 PVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQA 159 Query: 110 IRLMGDKVSAIAAMKKAGVPCVPGSDGPLG-------------------------DDMDK 144 + +GDK+++ + AG+P +P S L D+D Sbjct: 160 MWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDD 219 Query: 145 NRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYL 204 A+ +GYPV+IKAS GGGG+G+R V + +AE + +++ + Sbjct: 220 GLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGS----PIFVMRLA 275 Query: 205 ENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCA-KA 263 + RH+E+Q+LAD GNAI L RDCS+QRRHQK++EEAPA TP + ++ E+CA K Sbjct: 276 KQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHM-EQCAVKL 334 Query: 264 CVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPL- 321 +GY AGT E+L+ ++G FYF+E+N R+QVEHP TEM+ V+L QL+IA G PL Sbjct: 335 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLY 394 Query: 322 SIK------------------QEEVHV---RGHAVECRINAEDPNT-FLPSPGKITRFHA 359 IK ++ HV RGH + RI +E+P+ F PS G + + Sbjct: 395 RIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNF 454 Query: 360 PGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDG-IKTNV 418 V + A + + DS G +GENR+ AI+ M AL+EL I G +T V Sbjct: 455 RSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTV 514 Query: 419 DLQIRIMNDENFQHGGTNIHYLEK 442 + I+++ E+FQ + +L++ Sbjct: 515 EYLIKLLETESFQMNRIDTGWLDR 538 >3JRW-A nrPDB Length = 587 Score = 243 bits (621), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 160/505 (31%), Positives = 263/505 (52%), Gaps = 70/505 (13%) Query: 1 MLDKIVIANRGEIALRILRACK---------ELGIKTVAVHSSAD--RDLKHVLLADETV 49 +++K++IAN G A++ +R+ + E I+ V + + D + +++ +AD V Sbjct: 55 VIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYV 114 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAET 109 + P+ +Y N+ I+ A+ A+ G+G SEN E + ++G F+GP +E Sbjct: 115 PVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEA 174 Query: 110 IRLMGDKVSAIAAMKKAGVPCVPGSDGPLG-----DDMDKNRAI---------------- 148 + +GDK+++ + VP +P S L DD+ + + I Sbjct: 175 MWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVD 234 Query: 149 -----AKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKY 203 A+RIG+P++IKAS GGGG+G+R AE A+ + + ++ +++ K Sbjct: 235 EGLEAAERIGFPLMIKASEGGGGKGIR----KAESAEDFPILFRQVQSEIPGSPIFLMKL 290 Query: 204 LENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCA-K 262 ++ RH+E+Q+LAD GNA+ L RDCS+QRRHQK+VEEAPA I P E+CA + Sbjct: 291 AQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPA-TIAPLAIFEFMEQCAIR 349 Query: 263 ACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPL 321 +GY AGT E+L+ ++G F+F+E+N R+QVEHP TEMI V+L QL+IA G PL Sbjct: 350 LAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPL 409 Query: 322 SIKQEEVHV-----------------------RGHAVECRINAEDPNT-FLPSPGKITRF 357 + +++ + RGH + RI +E+P+ F PS G + Sbjct: 410 H-RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQEL 468 Query: 358 HAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDG-IKT 416 + V + A + + DS G +GENR+ AI+ M AL+EL I G +T Sbjct: 469 NFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRT 528 Query: 417 NVDLQIRIMNDENFQHGGTNIHYLE 441 V+ I ++ E+FQ+ + +L+ Sbjct: 529 TVEYLINLLETESFQNNDIDTGWLD 553 >1W93-A nrPDB Length = 553 Score = 233 bits (594), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 160/516 (31%), Positives = 253/516 (49%), Gaps = 85/516 (16%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKT-----------VAVHSSADRDLKHVLLADETV 49 ++ KI+IAN G A++ +R+ ++ +T +A + + +++ +AD+ + Sbjct: 45 VISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYI 104 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSG--FIFIGPKA 107 + + +Y N+ I+ AE A+ G+G SEN E++ +S IFIGP Sbjct: 105 EVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPG 164 Query: 108 ETIRLMGDKVSAIAAMKKAGVPCVPGS---------DGPLG-----DDM---------DK 144 +R +GDK+S+ + A VPC+P S D G DD+ + Sbjct: 165 NAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPED 224 Query: 145 NRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYL 204 AKRIG+PV+IKAS GGGG+G+R V E + +A +++ K Sbjct: 225 GLQKAKRIGFPVMIKASEGGGGKGIRQV----EREEDFIALYHQAANEIPGSPIFIMKLA 280 Query: 205 ENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKAC 264 RH+E+Q+LAD G I L RDCS+QRRHQK++EEAP E + + + Sbjct: 281 GRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLG 340 Query: 265 VDIGYRGAGTFEFLF--ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPL- 321 +GY AGT E+L+ ++G+FYF+E+N R+QVEHP TEM++GV+L QL+IA G P+ Sbjct: 341 KLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMH 400 Query: 322 ----------------------------SIKQEEVHVRGHAVECRINAEDPNT-FLPSPG 352 + KQ +GH CRI +EDPN F PS G Sbjct: 401 RISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGG 460 Query: 353 KITRFHAPGGFGVRWESHIYAGYTV------PPYYDSMIGKLICYGENRDVAIARMKNAL 406 + + R S+++ ++V + DS G + +GENR + M AL Sbjct: 461 TLHELN------FRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVAL 514 Query: 407 QELIIDG-IKTNVDLQIRIMNDENFQHGGTNIHYLE 441 +EL I G +T V+ I+++ E+F+ +L+ Sbjct: 515 KELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLD 550 >2CQY-A nrPDB Length = 108 Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 43/97 (44%), Positives = 63/97 (64%), Gaps = 1/97 (1%) Query: 114 GDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVR 173 GDK+ + KKA V +PG DG + D + R IA+ IGYPV+IKAS GGGG+GMR+ Sbjct: 7 GDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVR-IAREIGYPVMIKASAGGGGKGMRIAW 65 Query: 174 GDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHV 210 D E ++ EA ++F +D + +EK+++NPRH+ Sbjct: 66 DDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHI 102 >2YW2-A nrPDB Length = 424 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 68/294 (23%), Positives = 118/294 (40%), Gaps = 37/294 (12%) Query: 93 EQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRI 152 ++ E+ G GP E +L G K A MKK G+P + + D +K + +++ Sbjct: 80 DEFEKRGLKIFGPNKEAAKLEGSKAFAKTFMKKYGIPT---ARYEVFTDFEKAKEYVEKV 136 Query: 153 GYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEI 212 G P+++KA G G+G V + +++ + S++ V +E++LE I Sbjct: 137 GAPIVVKADGLAAGKGAVVCETVEKAIETLDRFLNKKIFGKSSERVVIEEFLEGEEASYI 196 Query: 213 QVLADGQGNAIYLAERDCSMQRRHQKVVEE------------APAPGITPE----LRRYI 256 V+ +G +D H+++++E +P P I E +R I Sbjct: 197 -VMINGDRYVPLPTSQD------HKRLLDEDKGPNTGGMGAYSPTPVINEEVEKRIREEI 249 Query: 257 GERCAKACVDIG--YRGAGTFEFLFENGEFYFIEMNTRI-QVEHPVTEMITGVDLIKEQL 313 ER K + G YRG + +E N R+ E M D ++ L Sbjct: 250 VERVIKGLKEEGIYYRGFLYAGLMITKEGPKVLEFNVRLGDPEAQPILMRVKNDFLETLL 309 Query: 314 RIAAGQPLSIKQEEVHVRGHAVECRINAEDPNT--------FLPSPGKITRFHA 359 G+ + IK++E + + R E P T +L S + FHA Sbjct: 310 NFYEGKDVHIKEDERYALDVVLASRGYPEKPETGKIIHGLDYLKSMEDVVVFHA 363 >3VPD-A nrPDB Length = 281 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 6/120 (5%) Query: 106 KAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGG 165 + E I GDK + A+ KAG+P L D ++ + + GYPV++K G Sbjct: 79 RPEVIEACGDKWATSVALAKAGLP---QPKTALATDREEALRLMEAFGYPVVLKPVIGSW 135 Query: 166 GRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RHVEIQVLADGQGNAIY 224 GR + V A A + E F + + Y+++Y+E P R + + V+ + AIY Sbjct: 136 GRLLAKVTDRA--AAEALLEHKEVLGGFQHQLFYIQEYVEKPGRDIRVFVVGERAIAAIY 193 >3AW8-A nrPDB Length = 369 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 67/294 (22%), Positives = 114/294 (38%), Gaps = 33/294 (11%) Query: 57 VKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDK 116 V +L+ A++ AE V Y F + A ++E G + + P A+ + + D+ Sbjct: 44 VGEFLDEGALLRFAEGLALVT----YEFENVPVEAARRLE--GRLPLYPPAKALEVAQDR 97 Query: 117 VSAIAAMKKAGVPCVPGS--DGPLGDDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVR 173 + + GVP P DGP +D+++ KR+G P ++K GG G+G +VR Sbjct: 98 LREKTFFQGLGVPTPPFHPVDGP--EDLEEG---LKRVGLPALLKTRRGGYDGKGQALVR 152 Query: 174 GDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQ 233 + E +++ A + +E ++ R V + + G + ++ Sbjct: 153 TEEEALEALK--------ALGGRGLILEGFVPFDREVSLLAVRGRTGEVAFYP----LVE 200 Query: 234 RRHQKVV---EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMN 290 RH + APAPG + L++ +A + Y G EF E F EM Sbjct: 201 NRHWGGILRLSLAPAPGASEALQKKAEAYALRAMEALDYVGVLALEFFQVGEELLFNEMA 260 Query: 291 TRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP 344 R+ T + LR G PL RG + + E P Sbjct: 261 PRVHNSGHWTIEGAETSQFENHLRAVLGLPLG----STAPRGQSAMVNLIGEKP 310 >3ORR-A nrPDB Length = 377 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 25/191 (13%) Query: 108 ETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGG-GG 166 + I+L+ D+++ +K AG VP D+DK AI + +GYP I+K GG G Sbjct: 103 QAIQLLQDRLTEKETLKSAGTKVVPFISVKESTDIDK--AI-ETLGYPFIVKTRFGGYDG 159 Query: 167 RGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIY-- 224 +G ++ + +L + + A EKYL + V + V G N I Sbjct: 160 KGQVLINNEKDLQEGFKLIETSECVA--------EKYLNIKKEVSLTV-TRGNNNQITFF 210 Query: 225 -LAERDCSMQRRHQKVVEEAPAP-GITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-N 281 L E + Q + +V PA T E + E+ K I + G T EF + N Sbjct: 211 PLQENEHRNQILFKTIV---PARIDKTAEAK----EQVNKIIQSIHFIGTFTVEFFIDSN 263 Query: 282 GEFYFIEMNTR 292 + Y E+ R Sbjct: 264 NQLYVNEIAPR 274 >1UC8-A nrPDB Length = 280 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 6/120 (5%) Query: 106 KAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGG 165 + E I GDK + A+ KAG+P L D ++ + + GYPV++K G Sbjct: 79 RPEVIEACGDKWATSVALAKAGLP---QPKTALATDREEALRLMEAFGYPVVLKPVIGSW 135 Query: 166 GRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RHVEIQVLADGQGNAIY 224 GR + E F + + Y+++Y+E P R + + V+ + AIY Sbjct: 136 GRLL--AXXXXXXXXXXXXXXKEVLGGFQHQLFYIQEYVEKPGRDIRVFVVGERAIAAIY 193 >4C5A-A nrPDB Length = 330 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 54/226 (23%), Positives = 91/226 (40%), Gaps = 22/226 (9%) Query: 76 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSD 135 +A+H G G E+ +E G + G L DK+ + + AG+P P Sbjct: 84 IALH-GRG--GEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVA 140 Query: 136 GPLGDD----MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKA 191 + DK A +G PVI+K S G GM V + L ++ + Sbjct: 141 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRL------- 193 Query: 192 AFSND-MVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAP 246 AF +D V +EK+L P + +L + +I + + + +E PA Sbjct: 194 AFQHDEEVLIEKWLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA- 251 Query: 247 GITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 G+ + KA +G +G G + + + +G+FY +E NT Sbjct: 252 GLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 297 >2XD4-A nrPDB Length = 422 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 30/220 (13%) Query: 93 EQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRI 152 ++ E++G GP + G K A MKK +P ++ D+ +A + Sbjct: 80 DEFEKAGLHVFGPSKAAAIIEGSKQFAKDLMKKYDIPT---AEYETFTSFDEAKAYVQEK 136 Query: 153 GYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEI 212 G P++IKA G G+G+ V + E + + K ++ V +E+YL E Sbjct: 137 GAPIVIKADGLAAGKGVTVAMTEEEAIACLHDFLEDEKFGDASASVVIEEYLSGE---EF 193 Query: 213 QVLADGQGNAIYLAERDCSMQRRHQKVVE------------EAPAPGITPELRRYIGER- 259 ++A +G +Y + + H++ + +P P I+ E R+ E Sbjct: 194 SLMAFVKGEKVY----PMVIAQDHKRAFDGDKGPNTGGMGAYSPVPQISEETVRHAVETI 249 Query: 260 ---CAKACVDIGYRGAGTFE---FLFENGEFYFIEMNTRI 293 AKA V G G L ENG IE N R Sbjct: 250 VKPAAKAMVQEGRSFTGVLYAGLMLTENGS-KVIEFNARF 288 >2YS6-A nrPDB Length = 451 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/126 (25%), Positives = 53/126 (42%), Gaps = 6/126 (4%) Query: 99 GFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVII 158 G GP + G K A MKK G+P +D ++ +A ++ G P++I Sbjct: 107 GLRIFGPSQRAALIEGSKAFAKELMKKYGIPT---ADHAAFTSYEEAKAYIEQKGAPIVI 163 Query: 159 KASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG 218 KA G G+G+ V + E + + + + V +E+YLE E +A Sbjct: 164 KADGLAAGKGVTVAQTVEEALAAAKAALVDGQFGTAGSQVVIEEYLEGE---EFSFMAFV 220 Query: 219 QGNAIY 224 G +Y Sbjct: 221 NGEKVY 226 >2R84-A nrPDB Length = 334 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 45/157 (28%), Positives = 68/157 (43%), Gaps = 30/157 (19%) Query: 14 ALRILRACKELGIKTVAVHSSADRDL--KHVLLADETVCIGPAPSVKSYLNIPAIISAAE 71 AL+IL+ K+ G +T+A SS + L K+ +AD I + LN+ A++ Sbjct: 13 ALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVAD--YFIEEKYPEEELLNLNAVVVP-- 68 Query: 72 ITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCV 131 TG+ H G E VE + G K +R D+ +KKAG+ Sbjct: 69 -TGSFVAHLG----------IELVENMKVPYFGNK-RVLRWESDRNLERKWLKKAGIRVP 116 Query: 132 PGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRG 168 + P DD++K PVI+K G GG+G Sbjct: 117 EVYEDP--DDIEK----------PVIVKPHGAKGGKG 141 >3AX6-A nrPDB Length = 380 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 19/120 (15%) Query: 103 IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASG 162 I P T+ ++ DK +KK G+P VP + L D++ + + G+PV+ KA Sbjct: 88 IHPSPYTLEIIQDKFVQKEFLKKNGIP-VP--EYKLVKDLESD---VREFGFPVVQKARK 141 Query: 163 GG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGN 221 GG GRG+ +++ + +L +I Y+E+++E + + + V + +G Sbjct: 142 GGYDGRGVFIIKNEKDLENAI------------KGETYLEEFVEIEKELAVMVARNEKGE 189 >4WD3-A nrPDB Length = 413 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 3/123 (2%) Query: 97 RSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPV 156 RS F GP ET M +K++ +K G+P +D ++ A +++G+P+ Sbjct: 92 RSYFGIAGPGFETALYMTNKLAMKTKLKMEGIPV---ADFLCVSQVEDIPAAGEKLGWPI 148 Query: 157 IIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLA 216 I+K + G G ++ S + + +N ++ EK +E + A Sbjct: 149 IVKPALGSGALNTFIIHSLDHYEDLYSTSGGLGELKKNNSLMIAEKCIEMEEFHCDTLYA 208 Query: 217 DGQ 219 DG+ Sbjct: 209 DGE 211 >3QFF-A nrPDB Length = 389 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 58/240 (24%), Positives = 107/240 (44%), Gaps = 25/240 (10%) Query: 57 VKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDK 116 V SY ++ AI AEI+ V Y F + + + +E+ ++ G ++ + ++ Sbjct: 60 VASYDDLKAIQHLAEISDVVT----YEFENIDYRCLQWLEKHAYLPQG--SQLLSKTQNR 113 Query: 117 VSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGD 175 + A++KAG+P + + + AIA+ + YP ++K + GG G+G V+R + Sbjct: 114 FTEKNAIEKAGLPV--ATYRLVQNQEQLTEAIAE-LSYPSVLKTTTGGYDGKGQVVLRSE 170 Query: 176 AELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVL--ADGQGNAIYLAERDCSMQ 233 A++ ++ R A AA +EK++ + V + V+ G+ +AE Sbjct: 171 ADVDEA----RKLANAA----ECILEKWVPFEKEVSVIVIRSVSGETKVFPVAENIHVNN 222 Query: 234 RRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNTR 292 H+ +V PA IT EL + ++ G E F +GE Y E+ R Sbjct: 223 ILHESIV---PA-RITEELSQKAIAYAKVLADELELVGTLAVEMFATADGEIYINELAPR 278 >2FB9-A nrPDB Length = 322 Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust. Identities = 52/218 (23%), Positives = 83/218 (38%), Gaps = 22/218 (10%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDD 141 +G E+ +E G ++G L DK + + +AGVP VP Sbjct: 85 HGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVA------ 138 Query: 142 MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMT-RAEAKAAFSNDMVYM 200 + K P +K + G G+ V +L ++++ R + KA + Sbjct: 139 VRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAV-------V 191 Query: 201 EKYLENPRHVEIQVLADGQGNAIYLAE-------RDCSMQRRHQKVVEEAPAPGITPELR 253 EK L R +E+ VL + G A + E D + + PAP + P + Sbjct: 192 EKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAP-LDPGTQ 250 Query: 254 RYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNT 291 + E KA +G RG +F GE Y E+NT Sbjct: 251 ETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNT 288 >1E4E-B nrPDB Length = 343 Score = 35.4 bits (80), Expect = 0.055, Method: Compositional matrix adjust. Identities = 57/231 (24%), Positives = 87/231 (37%), Gaps = 30/231 (12%) Query: 76 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSD 135 VA +G E+ + E SG F+G ++ + DK K AG+ P Sbjct: 93 VAFSALHGKSGEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIA-TPAFW 151 Query: 136 GPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSN 195 DD R +A YPV +K + G G++ V EL +I R + Sbjct: 152 VINKDD----RPVAATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQ------YD 201 Query: 196 DMVYMEKYLENPRHVEIQVLADGQGNAIYLAERD-----CSMQRRHQKVVEE-------- 242 + +E+ + E+ G A+ + E D + R HQ+V E Sbjct: 202 SKILIEQAVSG---CEVGCAVLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVI 258 Query: 243 -APAPGITPELRRYIGERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNT 291 PA ++ E R I E K +G RG + FL + G E+NT Sbjct: 259 TVPA-DLSAEERGRIQETVKKIYKTLGCRGLARVDMFLQDRGRIVLNEVNT 308 >2IP4-A nrPDB Length = 417 Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust. Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 12/142 (8%) Query: 90 NFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIA 149 A+ + G + GP + + G K A M++ G+P + + + + A Sbjct: 76 GIADAFQARGLLLFGPTQKAAMIEGSKAFAKGLMERYGIPT---ARYRVFREPLEALAYL 132 Query: 150 KRIGYPVIIKASGGGGGRGMRVVRGDAELAQSIS--MTRAEAKAAFSNDMVYMEKYLENP 207 + +G PV++K SG G+G+ V + Q+++ + RAE V +E+YLE Sbjct: 133 EEVGVPVVVKDSGLAAGKGVTVAFDLHQAKQAVANILNRAE------GGEVVVEEYLEG- 185 Query: 208 RHVEIQVLADGQGNAIYLAERD 229 + L DG+ L +D Sbjct: 186 EEATVLALTDGETILPLLPSQD 207 >1EZ1-A nrPDB Length = 392 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 18/180 (10%) Query: 4 KIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNI 63 ++++ GE+ + C+ LG++ +AV AD HV + + L+ Sbjct: 14 RVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVI---------NMLDG 64 Query: 64 PAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDK--VSAIA 121 A+ E+ I P ++ + Q+E G + P A +L ++ + +A Sbjct: 65 DALRRVVELEKPHYIVPEIEAIATDMLI--QLEEEGLNVV-PCARATKLTMNREGIRRLA 121 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 A + +P S D R IGYP I+K G+G +R +LAQ+ Sbjct: 122 AEELQ----LPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQA 177 >5D8D-A nrPDB Length = 308 Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 18/184 (9%) Query: 115 DKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRG 174 DKV + + +P P D+D ++ +G PVIIK G GM V Sbjct: 99 DKVKTKQIWQGSDLPTAPYRIITKETDLD---SVIAELGLPVIIKPVHEGSSVGMSKVEK 155 Query: 175 DAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSM-- 232 + A +I KA + +V EK++ R I L +GQ + + + Sbjct: 156 AEDFAAAIE------KATQHDAVVMAEKWITG-REFTISFL-NGQPLPVIRLQPPADVAF 207 Query: 233 ---QRRHQKVVEEAPAP-GITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFI 287 + ++Q+ E P G++ + + C +A +G G G + + E G F+ + Sbjct: 208 YDYEAKYQRNDVEYGIPCGLSETEEKKLQALCLRAFQAVGAEGWGRIDAMQDEQGNFWLL 267 Query: 288 EMNT 291 E+NT Sbjct: 268 EVNT 271 >2CZG-A nrPDB Length = 433 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 18/213 (8%) Query: 4 KIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNI 63 KI++ GE+ I + LG++ VAV A+ + + V + ++ Sbjct: 21 KILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAP---------AMQVAHRSYVGNMMDK 71 Query: 64 PAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAM 123 + S E AI P ++ +A F + E+ G+ F+ P A + + + Sbjct: 72 DFLWSVVEREKPDAIIPEIEAINLDALF--EFEKDGY-FVVPNARATWIAMHRERLRETL 128 Query: 124 KKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSIS 183 K VP S +D+ ++IGYP KA G+G V+G ++ + + Sbjct: 129 VKEA--KVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK--A 184 Query: 184 MTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLA 216 A+ KA S + + +E++++ VE+ LA Sbjct: 185 WEEAKTKARGSAEKIIVEEHIDF--DVEVTELA 215 >5VEV-A nrPDB Length = 431 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 89/379 (23%), Positives = 148/379 (39%), Gaps = 73/379 (19%) Query: 89 ANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAI 148 A + +G GP +L K A A M K +P + ++ D Sbjct: 84 AGIVDDFRAAGLKIFGPTQYAAQLESSKDFAKAFMVKYNIPT---AQYQTFENADAAHDY 140 Query: 149 AKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR 208 + G P++IKA G G+G+ V +MT EA AA +DM+ K Sbjct: 141 VNQKGAPIVIKADGLVAGKGVIV-----------AMTLDEAHAAI-DDMLLGNKMGNAGE 188 Query: 209 HVEIQVLADGQGNAIYLAERD------CSMQRRHQKVVE------------EAPAPGITP 250 V I+ G+ A ++ D + + H+++++ +PAP +TP Sbjct: 189 RVVIEDFLQGE-EASFIVMVDGNHVLPMATSQDHKRLLDGDKGPNTGGMGAYSPAPVVTP 247 Query: 251 EL-RRYIGERCAKACVDIGYRGAGTFEFLF------ENGEFYFIEMNTRIQVEHPVTEMI 303 + R + E + G FL+ ++G Y IE N R P T+ I Sbjct: 248 AVYERAMNEIILPTVAGMKAEGHEFTGFLYAGLMIDQSGAPYTIEFNCRFG--DPETQPI 305 Query: 304 TG------VDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAED-PNTFLPSPGKITR 356 DL++ + G+ S+K E AV + A++ P T P G + Sbjct: 306 MSRLNSDLADLVEAAID---GRLDSVKAE--WNPQTAVGVVLAAQNYPET--PKKGDVIS 358 Query: 357 FHAPGGFGV----RWESHIYAGYTVPPYYDSMI--GKLIC-YGENRDVAIARMK--NALQ 407 G+ R +AG TV D + G+++C G DVA A+ K AL+ Sbjct: 359 -------GLDDVNRIGKVFHAGTTVNEKGDVLTNGGRILCVVGLGDDVAQAKAKAYGALE 411 Query: 408 ELIIDGIKTNVDLQIRIMN 426 ++ DG++ D+ + +N Sbjct: 412 KISFDGMQYRKDIADKAIN 430 >3MJF-A nrPDB Length = 431 Score = 32.3 bits (72), Expect = 0.40, Method: Compositional matrix adjust. Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 15/122 (12%) Query: 98 SGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVI 157 +G GP +L G K + + +P + D++ A ++ G P++ Sbjct: 90 AGLAIFGPTQAAAQLEGSKAFTKDFLARHNIPSAEYQNFT---DVEAALAYVRQKGAPIV 146 Query: 158 IKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLAD 217 IKA G G+G+ V +MT+ EA+ A NDM+ + + + ++ D Sbjct: 147 IKADGLAAGKGVIV-----------AMTQEEAETAV-NDMLAGNAFGDAGHRIVVEEFLD 194 Query: 218 GQ 219 G+ Sbjct: 195 GE 196 >2I87-A nrPDB Length = 364 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 7/82 (8%) Query: 146 RAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLE 205 + + ++ YPV +K + G G+ +AEL + I K AF D + + Sbjct: 164 KLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGI-------KEAFQFDRKLVIEQGV 216 Query: 206 NPRHVEIQVLADGQGNAIYLAE 227 N R +E+ VL + A + E Sbjct: 217 NAREIEVAVLGNDYPEATWPGE 238 >4HGN-A nrPDB Length = 176 Score = 31.6 bits (70), Expect = 0.74, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 12/69 (17%) Query: 104 GPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGG 163 G + I MGD V I M++ G+PC P D + + +++AK I Y + G Sbjct: 102 GLSDDEILYMGDDVPDIEVMRECGLPCCP------KDAVPEVKSVAKYISY------ADG 149 Query: 164 GGGRGMRVV 172 G G G VV Sbjct: 150 GRGCGRDVV 158 >3K3P-A nrPDB Length = 383 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 14/151 (9%) Query: 148 IAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP 207 + +++ YPV +K + G G+ +L Q+I++ A + V +E+ + + Sbjct: 196 VEEKLIYPVFVKPANMGSSVGISKAENRTDLKQAIAL------ALKYDSRVLIEQGV-DA 248 Query: 208 RHVEIQVLADGQGNAIYLAE--RDCSMQRRHQKVVEEAPAPGITPELRRYIGER----CA 261 R +E+ +L + E +D + K ++ I E+ I E+ A Sbjct: 249 REIEVGILGNTDVKTTLPGEIVKDVAFYDYEAKYIDNKITMAIPAEIDPVIVEKMRDYAA 308 Query: 262 KACVDIGYRGAGTFEF-LFENGEFYFIEMNT 291 A +G G +F L E+G+ Y E+NT Sbjct: 309 TAFRTLGCCGLSRCDFFLTEDGKVYLNELNT 339 >1VKZ-A nrPDB Length = 412 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 103 IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASG 162 GP E RL G KV A MKK G+ + + + ++ R K+ P +IKA G Sbjct: 94 FGPVKEVARLEGSKVYAKRFMKKYGIRT---ARFEVAETPEELREKIKKFSPPYVIKADG 150 Query: 163 GGGGRGMRVVRGDAELAQSIS 183 G+G+ ++ E + S Sbjct: 151 LARGKGVLILDSKEETIEKGS 171 >5BPF-A nrPDB Length = 306 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 9/72 (12%) Query: 147 AIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDM-VYMEKYLE 205 A ++G P+I+K S G GM V +EL +++ AF +D V +EK+L Sbjct: 132 ACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALV-------EAFQHDSDVLIEKWLS 184 Query: 206 NPRHVEIQVLAD 217 P + +L D Sbjct: 185 GPEFT-VAILGD 195 >1GSO-A nrPDB Length = 431 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 39/180 (21%), Positives = 75/180 (41%), Gaps = 34/180 (18%) Query: 98 SGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVI 157 +G GP A +L G K + + +P + +++ A + G P++ Sbjct: 89 AGLKIFGPTAGAAQLEGSKAFTKDFLARHKIPTAEYQNFT---EVEPALAYLREKGAPIV 145 Query: 158 IKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLAD 217 IKA G G+G+ V +MT EA+AA +DM+ + + + I+ D Sbjct: 146 IKADGLAAGKGVIV-----------AMTLEEAEAAV-HDMLAGNAFGDAGHRIVIEEFLD 193 Query: 218 GQGNAIYLAERD------CSMQRRHQKVVEE------------APAPGITPELRRYIGER 259 G+ A ++ D + + H++V ++ +PAP +T ++ + ER Sbjct: 194 GE-EASFIVMVDGEHVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTDDVHQRTMER 252 >3R5X-A nrPDB Length = 307 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 8/64 (12%) Query: 143 DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDM-VYME 201 D N ++G+P+++K + GG G+++V EL ISM + F D V +E Sbjct: 123 DLNFDELDKLGFPLVVKPNSGGSSVGVKIVYDKDEL---ISML----ETVFEWDSEVVIE 175 Query: 202 KYLE 205 KY++ Sbjct: 176 KYIK 179 >2QK4-A nrPDB Length = 452 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 41/199 (20%), Positives = 78/199 (39%), Gaps = 24/199 (12%) Query: 89 ANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAI 148 A + +G GP AE +L K A M + G+P + ++ + Sbjct: 102 AGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPT---AQWKAFTKPEEACSF 158 Query: 149 AKRIGYP-VIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP 207 +P +++KASG G+G+ V + E +++ E + + + +E+ L+ Sbjct: 159 ILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG- 217 Query: 208 RHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE------------EAPAPGITPELRRY 255 V DG+ A +D H++++E PAP ++ +L Sbjct: 218 EEVSCLCFTDGKTVAPMPPAQD------HKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLK 271 Query: 256 IGERCAKACVDIGYRGAGT 274 I + + VD G + GT Sbjct: 272 IKDTVLQRTVD-GMQQEGT 289 >3LP8-A nrPDB Length = 442 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 28/141 (19%), Positives = 51/141 (36%), Gaps = 8/141 (5%) Query: 91 FAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRA--I 148 ++ + G + GP RL K + G+P G +D N A Sbjct: 99 LSDALTEEGILVFGPSKAAARLESSKGFTKELCMRYGIPT-----AKYGYFVDTNSAYKF 153 Query: 149 AKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR 208 + P+++KA G G+G + E ++ K + + +E++LE + Sbjct: 154 IDKHKLPLVVKADGLAQGKGTVICHTHEEAYNAVDAMLVHHKFGEAGCAIIIEEFLEG-K 212 Query: 209 HVEIQVLADGQGNAIYLAERD 229 + L DG I +D Sbjct: 213 EISFFTLVDGSNPVILGVAQD 233 >3VOT-A nrPDB Length = 425 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 41/192 (21%), Positives = 85/192 (44%), Gaps = 12/192 (6%) Query: 150 KRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDM-----VYMEKYL 204 +++ YP+++K G +G+ V EL +++ A + + + + E+++ Sbjct: 142 RKLSYPLVVKPVNGFSSQGVVRVDDRKELEEAVRKVEAVNQRDLNRFVHGKTGIVAEQFI 201 Query: 205 ENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKAC 264 + P + G + + + + S ++ V APA + E R I + A Sbjct: 202 DGPEFAIETLSIQGNVHVLSIGYKGNSKGPFFEEGVYIAPA-QLKEETRLAIVKEVTGAV 260 Query: 265 VDIG-YRGAGTFEF-LFENGEFYFIEMNTRI---QVEHPVTEMITGVDLIKEQLRIAAGQ 319 +G ++G E L ++G Y IE+ RI V H + + TG++ ++ L+ A + Sbjct: 261 SALGIHQGPAHTELRLDKDGTPYVIEVGARIGGSGVSHYIVKESTGINFMQLVLQNAL-K 319 Query: 320 PLSIKQEEVHVR 331 PL + E +R Sbjct: 320 PLESSEFEGEIR 331 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3JZF-A nrPDB 679 0.0 4RZQ-A nrPDB 639 0.0 2C00-A nrPDB 630 0.0 2VPQ-A nrPDB 595 e-170 1ULZ-A nrPDB 565 e-161 2DZD-A nrPDB 558 e-159 3OUU-A nrPDB 553 e-158 3N6R-A nrPDB 553 e-158 2YL2-A nrPDB 525 e-149 3U9T-A nrPDB 524 e-149 3JRW-A nrPDB 513 e-146 1W93-A nrPDB 489 e-138 5MLK-A nrPDB 483 e-137 5H80-A nrPDB 476 e-134 5KS8-A nrPDB 413 e-116 2YW2-A nrPDB 234 8e-62 3AW8-A nrPDB 221 6e-58 4C5A-A nrPDB 169 2e-42 3ORR-A nrPDB 169 3e-42 2XD4-A nrPDB 167 6e-42 2YS6-A nrPDB 164 1e-40 3VPD-A nrPDB 111 6e-25 2CQY-A nrPDB 108 5e-24 1UC8-A nrPDB 104 7e-23 Sequences not found previously or not previously below threshold: 3MJF-A nrPDB 138 4e-33 1GSO-A nrPDB 135 4e-32 2IP4-A nrPDB 130 2e-30 5BPF-A nrPDB 127 1e-29 3QFF-A nrPDB 125 3e-29 5VEV-A nrPDB 125 3e-29 3AX6-A nrPDB 120 9e-28 2QK4-A nrPDB 117 1e-26 4IZO-A nrPDB 116 2e-26 4MAM-A nrPDB 112 3e-25 4EGJ-A nrPDB 111 8e-25 5D8D-A nrPDB 109 2e-24 3LP8-A nrPDB 108 5e-24 4E4T-A nrPDB 108 5e-24 3K5H-A nrPDB 108 6e-24 4EG0-A nrPDB 107 1e-23 2CZG-A nrPDB 105 3e-23 2Z04-A nrPDB 102 3e-22 3R5X-A nrPDB 100 1e-21 1VKZ-A nrPDB 100 2e-21 5NRH-A nrPDB 99 4e-21 3I12-A nrPDB 97 2e-20 2FB9-A nrPDB 96 2e-20 4FU0-A nrPDB 94 2e-19 1EZ1-A nrPDB 93 2e-19 2I87-A nrPDB 93 3e-19 4DIM-A nrPDB 92 6e-19 3VOT-A nrPDB 89 4e-18 1E4E-B nrPDB 89 4e-18 3LWB-A nrPDB 86 2e-17 3K3P-A nrPDB 86 4e-17 3ETH-A nrPDB 84 9e-17 3E5N-A nrPDB 79 4e-15 2PVP-A nrPDB 77 2e-14 6DGI-A nrPDB 77 2e-14 3WO0-A nrPDB 76 3e-14 5K2M-A nrPDB 70 2e-12 1EHI-A nrPDB 70 3e-12 3TQT-A nrPDB 69 3e-12 2PN1-A nrPDB 69 6e-12 3VPB-A nrPDB 55 5e-08 2R84-A nrPDB 53 2e-07 4WD3-A nrPDB 50 1e-06 4IWX-A nrPDB 50 2e-06 3UFX-B nrPDB 50 2e-06 3WVR-A nrPDB 47 1e-05 2NU8-B nrPDB 43 3e-04 1WR2-A nrPDB 43 3e-04 4XZ3-B nrPDB 43 3e-04 4FFM-A nrPDB 40 0.001 6G4Q-B nrPDB 40 0.002 3DF7-A nrPDB 39 0.004 5I47-A nrPDB 34 0.15 5UA0-A nrPDB 33 0.27 2A9V-A nrPDB 33 0.29 6MEL-B nrPDB 33 0.32 3JZG-A nrPDB 32 0.55 4P4R-B nrPDB 32 0.66 1CER-O nrPDB 31 1.1 1PK8-A nrPDB 31 1.3 2PZ0-A nrPDB 30 1.4 1N9W-A nrPDB 30 1.5 6MGG-B nrPDB 30 1.6 4QL6-A nrPDB 30 1.7 3S99-A nrPDB 30 1.9 4KP2-A nrPDB 30 2.6 5DZS-A nrPDB 30 2.7 5NQA-A nrPDB 30 3.1 5HAA-A nrPDB 29 3.2 2YYI-A nrPDB 29 4.3 4ROQ-A nrPDB 29 5.1 3NYS-A nrPDB 28 6.5 >3JZF-A nrPDB Length = 486 Score = 679 bits (1751), Expect = 0.0, Method: Composition-based stats. Identities = 449/449 (100%), Positives = 449/449 (100%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY Sbjct: 22 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 81 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI Sbjct: 82 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 141 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ Sbjct: 142 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 201 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV Sbjct: 202 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 261 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT Sbjct: 262 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 321 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP Sbjct: 322 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 381 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL Sbjct: 382 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 441 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQEK 449 QIRIMNDENFQHGGTNIHYLEKKLGLQEK Sbjct: 442 QIRIMNDENFQHGGTNIHYLEKKLGLQEK 470 >4RZQ-A nrPDB Length = 468 Score = 639 bits (1648), Expect = 0.0, Method: Composition-based stats. Identities = 368/448 (82%), Positives = 407/448 (90%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 ML+K+VIANRGEIALRILRACKELGIKTVAVHS+ADRDLKHVLLADET+CIGPAPS KSY Sbjct: 21 MLEKVVIANRGEIALRILRACKELGIKTVAVHSTADRDLKHVLLADETICIGPAPSAKSY 80 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LNIPAII+AAE+TGA AIHPGYGFLSENA+FAEQVERSGF FIGP A+ IRLMGDKVSAI Sbjct: 81 LNIPAIIAAAEVTGADAIHPGYGFLSENADFAEQVERSGFTFIGPTADVIRLMGDKVSAI 140 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AMKKAGVPCVPGSDGP+ +D+ KN+ IAKRIGYP+IIKASGGGGGRGMRVVR + L + Sbjct: 141 KAMKKAGVPCVPGSDGPVSNDIAKNKEIAKRIGYPIIIKASGGGGGRGMRVVRSEDALEE 200 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 SI+MT+AEAKAAF+NDMVYMEKYLENPRHVEIQVLAD GNA+YLAERDCSMQRRHQKVV Sbjct: 201 SIAMTKAEAKAAFNNDMVYMEKYLENPRHVEIQVLADTHGNAVYLAERDCSMQRRHQKVV 260 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGIT E+RR IG RCA ACV+IGYRGAGTFEFL+ENGEFYFIEMNTRIQVEHPVT Sbjct: 261 EEAPAPGITEEVRRDIGSRCANACVEIGYRGAGTFEFLYENGEFYFIEMNTRIQVEHPVT 320 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EMITGVDL+KEQLRIAAG P+S KQE++ V+GHA+ECRINAEDP TFLPSPGK+ H+P Sbjct: 321 EMITGVDLVKEQLRIAAGLPISFKQEDIKVKGHAMECRINAEDPKTFLPSPGKVNHLHSP 380 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GG GVRW+SH+Y GYTVPP+YDSMI KLI YG+ R+VAI RM+NAL E IIDGIKTN+ L Sbjct: 381 GGLGVRWDSHVYGGYTVPPHYDSMIAKLITYGDTREVAIRRMQNALSETIIDGIKTNIPL 440 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQE 448 I+ DENFQ GGTNIHYLEKKLG+ E Sbjct: 441 HELILEDENFQKGGTNIHYLEKKLGMNE 468 >2C00-A nrPDB Length = 464 Score = 630 bits (1625), Expect = 0.0, Method: Composition-based stats. Identities = 319/448 (71%), Positives = 388/448 (86%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 ML+K++IANRGEIALRILRACKELGIKTVAVHS+ADR+L H+ LADE+VCIGPAP+ +SY Sbjct: 1 MLEKVLIANRGEIALRILRACKELGIKTVAVHSTADRELMHLSLADESVCIGPAPATQSY 60 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L IPAII+AAE+TGA AIHPGYGFL+ENA+FAEQ+ERSGF F+GP AE IRLMGDKVSA Sbjct: 61 LQIPAIIAAAEVTGATAIHPGYGFLAENADFAEQIERSGFTFVGPTAEVIRLMGDKVSAK 120 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 AMK+AGVP VPGSDGPL +D + AIA+ +GYPVIIKA+GGGGGRGMRVV ++EL + Sbjct: 121 DAMKRAGVPTVPGSDGPLPEDEETALAIAREVGYPVIIKAAGGGGGRGMRVVYDESELIK 180 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 S +TR EA AAF N MVY+EK+L NPRHVE+QVL+DGQGNAI+L +RDCS+QRRHQKV+ Sbjct: 181 SAKLTRTEAGAAFGNPMVYLEKFLTNPRHVEVQVLSDGQGNAIHLGDRDCSLQRRHQKVI 240 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 EEAPAPGI + R+ + RC +AC++IGYRGAGTFEFL+ENG FYFIEMNTR+QVEHPV+ Sbjct: 241 EEAPAPGIDEKARQEVFARCVQACIEIGYRGAGTFEFLYENGRFYFIEMNTRVQVEHPVS 300 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EM+TGVD++KE LRIA+G+ LSI+QE+V +RGHA+ECRINAEDP TF+PSPGK+ FHAP Sbjct: 301 EMVTGVDIVKEMLRIASGEKLSIRQEDVVIRGHALECRINAEDPKTFMPSPGKVKHFHAP 360 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 GG GVR +SH+Y+GY+VPP YDS++GK+I YG +RD A+ARM+NAL ELI+DGIKTN +L Sbjct: 361 GGNGVRVDSHLYSGYSVPPNYDSLVGKVITYGADRDEALARMRNALDELIVDGIKTNTEL 420 Query: 421 QIRIMNDENFQHGGTNIHYLEKKLGLQE 448 ++ D F GG NIHYLEKKLG+ + Sbjct: 421 HKDLVRDAAFCKGGVNIHYLEKKLGMDK 448 >2VPQ-A nrPDB Length = 451 Score = 595 bits (1535), Expect = e-170, Method: Composition-based stats. Identities = 237/451 (52%), Positives = 319/451 (70%), Gaps = 4/451 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + K++IANRGEIA+RI+RAC++LGI+TVA++S D+D H +ADE C+GP S SYL Sbjct: 1 MKKVLIANRGEIAVRIIRACRDLGIQTVAIYSEGDKDALHTQIADEAYCVGPTLSKDSYL 60 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 NIP I+S A TG +HPGYGFL+ENA+FAE E FIGP ++I+ MG K A A Sbjct: 61 NIPNILSIATSTGCDGVHPGYGFLAENADFAELCEACQLKFIGPSYQSIQKMGIKDVAKA 120 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M KA VP VPGSDG L D+ + + IAK+IGYPVIIKA+ GGGG+G+RV R + EL Sbjct: 121 EMIKANVPVVPGSDG-LMKDVSEAKKIAKKIGYPVIIKATAGGGGKGIRVARDEKELETG 179 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 MT EA+ AF N +YMEK++EN RH+EIQ++ D GN I+L ERDC++QRR QK+VE Sbjct: 180 FRMTEQEAQTAFGNGGLYMEKFIENFRHIEIQIVGDSYGNVIHLGERDCTIQRRMQKLVE 239 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE--NGEFYFIEMNTRIQVEHPV 299 EAP+P + E RR +G +A + Y AGT EF+++ + +FYF+EMNTRIQVEHPV Sbjct: 240 EAPSPILDDETRREMGNAAVRAAKAVNYENAGTIEFIYDLNDNKFYFMEMNTRIQVEHPV 299 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 TEM+TG+DL+K QL++A G L KQE++ + GHA+E RINAE+P F+PSPGKI ++ Sbjct: 300 TEMVTGIDLVKLQLQVAMGDVLPYKQEDIKLTGHAIEFRINAENPYKNFMPSPGKIEQYL 359 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 APGG+GVR ES Y YT+PPYYDSM+ KLI + RD AI AL E ++ GI T + Sbjct: 360 APGGYGVRIESACYTNYTIPPYYDSMVAKLIIHEPTRDEAIMAGIRALSEFVVLGIDTTI 419 Query: 419 DLQIRIMNDENFQHGGTNIHYLEKKLGLQEK 449 I+++N++ F+ G N ++LE+ + ++ Sbjct: 420 PFHIKLLNNDIFRSGKFNTNFLEQNSIMNDE 450 >1ULZ-A nrPDB Length = 451 Score = 565 bits (1456), Expect = e-161, Method: Composition-based stats. Identities = 235/444 (52%), Positives = 312/444 (70%), Gaps = 4/444 (0%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M++K+++ANRGEIA+RI+RACKELGI TVA+++ + +HV LADE IG P + +Y Sbjct: 1 MVNKVLVANRGEIAVRIIRACKELGIPTVAIYNEVESTARHVKLADEAYMIGTDP-LDTY 59 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LN II+ A GA AIHPGYGFL+ENA FA+ E +G FIGP + I LMGDK + Sbjct: 60 LNKQRIINLALEVGADAIHPGYGFLAENAEFAKMCEEAGITFIGPHWKVIELMGDKARSK 119 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 MKKAGVP VPGSDG L +++ +A+A+ IGYPV++KA+ GGGGRG+R+ R + EL + Sbjct: 120 EVMKKAGVPVVPGSDGVL-KSLEEAKALAREIGYPVLLKATAGGGGRGIRICRNEEELVK 178 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 + EA+ AF + +EK++ENP+H+E QVL D GN I+L ERDCS+QRR+QK+V Sbjct: 179 NYEQASREAEKAFGRGDLLLEKFIENPKHIEYQVLGDKHGNVIHLGERDCSIQRRNQKLV 238 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFEN-GEFYFIEMNTRIQVEHPV 299 E AP+ +TPE R Y G KA +IGY AGT EF+ + G YFIEMNTRIQVEHPV Sbjct: 239 EIAPSLILTPEKREYYGNIVTKAAKEIGYYNAGTMEFIADQEGNLYFIEMNTRIQVEHPV 298 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 +EM+TG+D++K Q++IAAG+PL+IKQE+V G+A+ECRINAEDP F PS I R++ Sbjct: 299 SEMVTGIDIVKWQIKIAAGEPLTIKQEDVKFNGYAIECRINAEDPKKNFAPSTRVIERYY 358 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 PGGFG+R E G+ V PYYDSMI KLI + D A+ RM+ AL+ I G+KT + Sbjct: 359 VPGGFGIRVEHAAARGFEVTPYYDSMIAKLITWAPTWDEAVERMRAALETYEITGVKTTI 418 Query: 419 DLQIRIMNDENFQHGGTNIHYLEK 442 L I IM +++F+ G YLE+ Sbjct: 419 PLLINIMKEKDFKAGKFTTKYLEE 442 >2DZD-A nrPDB Length = 461 Score = 558 bits (1439), Expect = e-159, Method: Composition-based stats. Identities = 205/449 (45%), Positives = 290/449 (64%), Gaps = 10/449 (2%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAP-SVKSY 60 + K+++ANRGEIA+R+ RAC ELGI+TVA++S D H ADE +G +++Y Sbjct: 6 IRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKKPIEAY 65 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L+I II A+ AIHPGYGFLSEN FA++ G IFIGP + + GDKV A Sbjct: 66 LDIEGIIEIAKAHDVDAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKAR 125 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 A AG+P +PGSDGP+ D ++ A A+ GYP+IIKA+ GGGGRGMR+VR +E+ + Sbjct: 126 HAAVNAGIPVIPGSDGPV-DGLEDVVAFAEAHGYPIIIKAALGGGGRGMRIVRSKSEVKE 184 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 + ++EAKAAF +D VY+EK +ENP+H+E+Q+L D +GN ++L ERDCS+QRRHQKVV Sbjct: 185 AFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRHQKVV 244 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVT 300 E AP+ ++ ELR+ I E + +GY AGT EFL EFYFIE+N RIQVEH +T Sbjct: 245 EVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVEHTIT 304 Query: 301 EMITGVDLIKEQLRIAAGQPLSI------KQEEVHVRGHAVECRINAEDP-NTFLPSPGK 353 EMITG+D+++ Q+ IA G L KQE++ + G+A++ R+ EDP N F+P GK Sbjct: 305 EMITGIDIVQSQILIADGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMPDTGK 364 Query: 354 ITRFHAPGGFGVRWESH-IYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIID 412 I + + GGFGVR ++ + G + PYYDS++ KL + + A +M L+E I Sbjct: 365 IMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKLSTWALTFEQAARKMLRNLREFRIR 424 Query: 413 GIKTNVDLQIRIMNDENFQHGGTNIHYLE 441 GIKTN+ ++ F G + +++ Sbjct: 425 GIKTNIPFLENVVQHPKFLSGEYDTSFID 453 >3OUU-A nrPDB Length = 446 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 234/442 (52%), Positives = 310/442 (70%), Gaps = 3/442 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + I+IANRGEIALR LR KE+G K + V+S AD+D ++ AD ++CIG A S +SYL Sbjct: 6 IKSILIANRGEIALRALRTIKEMGKKAICVYSEADKDALYLKYADASICIGKARSSESYL 65 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 NIPAII+AAEI A AI PGYGFLSEN NF E + FIGP E + LM DK A Sbjct: 66 NIPAIIAAAEIAEADAIFPGYGFLSENQNFVEICAKHNIKFIGPSVEAMNLMSDKSKAKQ 125 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M++AGVP +PGSDG L + + +AK IGYPVI+KA+ GGGGRGMRVV + +L ++ Sbjct: 126 VMQRAGVPVIPGSDGALA-GAEAAKKLAKEIGYPVILKAAAGGGGRGMRVVENEKDLEKA 184 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 +EA AF + +YMEKY++NPRH+E+QV+ D GN I++ ERDCSMQRRHQK++E Sbjct: 185 YWSAESEAMTAFGDGTMYMEKYIQNPRHIEVQVIGDSFGNVIHVGERDCSMQRRHQKLIE 244 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENG-EFYFIEMNTRIQVEHPVT 300 E+PA + + R + E KA IGY GAGTFEFL + +FYFIEMNTR+QVEH V+ Sbjct: 245 ESPAILLDEKTRTRLHETAIKAAKAIGYEGAGTFEFLVDKNLDFYFIEMNTRLQVEHCVS 304 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP 360 EM++G+D+I++ +++A G L QE + + GH++ECRI AED TFLPSPGKIT++ P Sbjct: 305 EMVSGIDIIEQMIKVAEGYALP-SQESIKLNGHSIECRITAEDSKTFLPSPGKITKYIPP 363 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVDL 420 G VR ESH Y Y+VP YYDSMIGKL+ + E+R+ AIA+MK AL EL+I GIKT D Sbjct: 364 AGRNVRMESHCYQDYSVPAYYDSMIGKLVVWAEDRNKAIAKMKVALDELLISGIKTTKDF 423 Query: 421 QIRIMNDENFQHGGTNIHYLEK 442 + +M + +F + + +YL + Sbjct: 424 HLSMMENPDFINNNYDTNYLAR 445 >3N6R-A nrPDB Length = 681 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 209/465 (44%), Positives = 295/465 (63%), Gaps = 23/465 (4%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M +KI+IANRGEIA R+++ +++GI TVA++S AD+ HV +ADE V IGP P+ +SY Sbjct: 1 MFNKILIANRGEIACRVIKTARKMGISTVAIYSDADKQALHVQMADEAVHIGPPPANQSY 60 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 + I +++A TGA A+HPGYGFLSEN+ FAE +E G IF+GP I MGDK+++ Sbjct: 61 IVIDKVMAAIRATGAQAVHPGYGFLSENSKFAEALEAEGVIFVGPPKGAIEAMGDKITSK 120 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 ++A V VPG G L +D D+ I+ +IGYPV+IKAS GGGG+GMR+ D E + Sbjct: 121 KIAQEANVSTVPGYMG-LIEDADEAVKISNQIGYPVMIKASAGGGGKGMRIAWNDQEARE 179 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 ++ EA +F +D +++EK++ PRH+EIQVL D GN IYL ER+CS+QRR+QKVV Sbjct: 180 GFQSSKNEAANSFGDDRIFIEKFVTQPRHIEIQVLCDSHGNGIYLGERECSIQRRNQKVV 239 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFEN-GEFYFIEMNTRIQVEHPV 299 EEAP+P + RR +GE+ +GY AGT EF+ + FYF+EMNTR+QVEHPV Sbjct: 240 EEAPSPFLDEATRRAMGEQAVALAKAVGYASAGTVEFIVDGQKNFYFLEMNTRLQVEHPV 299 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP-NTFLPSPGKITRFH 358 TE+ITGVDL+++ +R+AAG+PLSI Q +V + G A+E R+ AEDP FLPS G++TR+ Sbjct: 300 TELITGVDLVEQMIRVAAGEPLSITQGDVKLTGWAIENRLYAEDPYRGFLPSIGRLTRYR 359 Query: 359 AP--------------------GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVA 398 P G VR ++ +Y G + YYD MI KL + R A Sbjct: 360 PPAETAAGPLLVNGKWQGDAPSGEAAVRNDTGVYEGGEISMYYDPMIAKLCTWAPTRAAA 419 Query: 399 IARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKK 443 I M+ AL ++GI N+ +M+ F G ++ ++ Sbjct: 420 IEAMRIALDSFEVEGIGHNLPFLSAVMDHPKFISGDMTTAFIAEE 464 >2YL2-A nrPDB Length = 540 Score = 525 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 158/503 (31%), Positives = 256/503 (50%), Gaps = 65/503 (12%) Query: 1 MLDKIVIANRGEIALRILRACK---------ELGIKTVAVHSSAD--RDLKHVLLADETV 49 +++K++IAN G A++ +R+ + E I+ V + + D + +++ +AD V Sbjct: 40 VIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYV 99 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAET 109 + P+ +Y N+ I+ A+ A+ G+G SEN E + ++G F+GP ++ Sbjct: 100 PVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQA 159 Query: 110 IRLMGDKVSAIAAMKKAGVPCVPGSDGPLG-------------------------DDMDK 144 + +GDK+++ + AG+P +P S L D+D Sbjct: 160 MWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDD 219 Query: 145 NRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYL 204 A+ +GYPV+IKAS GGGG+G+R V + +AE +++ + Sbjct: 220 GLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEV----PGSPIFVMRLA 275 Query: 205 ENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKAC 264 + RH+E+Q+LAD GNAI L RDCS+QRRHQK++EEAPA TP + ++ + K Sbjct: 276 KQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLA 335 Query: 265 VDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPL-- 321 +GY AGT E+L+ ++G FYF+E+N R+QVEHP TEM+ V+L QL+IA G PL Sbjct: 336 KMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYR 395 Query: 322 ----------------SIKQEEVH----VRGHAVECRINAEDPNT-FLPSPGKITRFHAP 360 I E+ RGH + RI +E+P+ F PS G + + Sbjct: 396 IKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFR 455 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDG-IKTNVD 419 V + A + + DS G +GENR+ AI+ M AL+EL I G +T V+ Sbjct: 456 SNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVE 515 Query: 420 LQIRIMNDENFQHGGTNIHYLEK 442 I+++ E+FQ + +L++ Sbjct: 516 YLIKLLETESFQMNRIDTGWLDR 538 >3U9T-A nrPDB Length = 655 Score = 524 bits (1350), Expect = e-149, Method: Composition-based stats. Identities = 224/444 (50%), Positives = 301/444 (67%), Gaps = 4/444 (0%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + ++++ANRGEIA R++R+ + LGI +VAVHS DR +HV AD V +G A SYL Sbjct: 8 IQRLLVANRGEIACRVMRSARALGIGSVAVHSDIDRHARHVAEADIAVDLGGAKPADSYL 67 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 II+AA +GA AIHPGYGFLSENA+FA E +G +F+GP A I MG K +A A Sbjct: 68 RGDRIIAAALASGAQAIHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKA 127 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M++AGVP VPG G D++ R A RIGYPV++KA+ GGGG+GM+VV +AELA++ Sbjct: 128 LMEEAGVPLVPGYHGE-AQDLETFRREAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEA 186 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 +S + EAKAAF + + +EKYL PRHVEIQV AD G+ +YL ERDCS+QRRHQKVVE Sbjct: 187 LSSAQREAKAAFGDARMLVEKYLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVE 246 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFEN-GEFYFIEMNTRIQVEHPVT 300 EAPAPG+ ELRR +GE +A IGY GAGT EFL + G+F+F+EMNTR+QVEHPVT Sbjct: 247 EAPAPGLGAELRRAMGEAAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNTRLQVEHPVT 306 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPN-TFLPSPGKITRFH- 358 E ITG+DL+ Q+R+A G+ L + QE+V + GHA+E R+ AEDP FLP+ G++ + Sbjct: 307 EAITGLDLVAWQIRVARGEALPLTQEQVPLNGHAIEVRLYAEDPEGDFLPASGRLMLYRE 366 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 A G G R +S + G V P+YD M+ KLI +GE R+ A R+ L E + G++TN+ Sbjct: 367 AAAGPGRRVDSGVREGDEVSPFYDPMLAKLIAWGETREEARQRLLAMLAETSVGGLRTNL 426 Query: 419 DLQIRIMNDENFQHGGTNIHYLEK 442 RI+ F + ++ + Sbjct: 427 AFLRRILGHPAFAAAELDTGFIAR 450 >3JRW-A nrPDB Length = 587 Score = 513 bits (1321), Expect = e-146, Method: Composition-based stats. Identities = 153/503 (30%), Positives = 255/503 (50%), Gaps = 66/503 (13%) Query: 1 MLDKIVIANRGEIALRILRACK---------ELGIKTVAVHSSAD--RDLKHVLLADETV 49 +++K++IAN G A++ +R+ + E I+ V + + D + +++ +AD V Sbjct: 55 VIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYV 114 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAET 109 + P+ +Y N+ I+ A+ A+ G+G SEN E + ++G F+GP +E Sbjct: 115 PVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEA 174 Query: 110 IRLMGDKVSAIAAMKKAGVPCVPGSDGPLG--------------------------DDMD 143 + +GDK+++ + VP +P S L D+D Sbjct: 175 MWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVD 234 Query: 144 KNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKY 203 + A+RIG+P++IKAS GGGG+G+R E A+ + + ++ +++ K Sbjct: 235 EGLEAAERIGFPLMIKASEGGGGKGIRKA----ESAEDFPILFRQVQSEIPGSPIFLMKL 290 Query: 204 LENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKA 263 ++ RH+E+Q+LAD GNA+ L RDCS+QRRHQK+VEEAPA + ++ + + Sbjct: 291 AQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRL 350 Query: 264 CVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLS 322 +GY AGT E+L+ ++G F+F+E+N R+QVEHP TEMI V+L QL+IA G PL Sbjct: 351 AKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH 410 Query: 323 IKQE----------------------EVHVRGHAVECRINAEDPNT-FLPSPGKITRFHA 359 ++ RGH + RI +E+P+ F PS G + + Sbjct: 411 RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNF 470 Query: 360 PGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDG-IKTNV 418 V + A + + DS G +GENR+ AI+ M AL+EL I G +T V Sbjct: 471 RSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTV 530 Query: 419 DLQIRIMNDENFQHGGTNIHYLE 441 + I ++ E+FQ+ + +L+ Sbjct: 531 EYLINLLETESFQNNDIDTGWLD 553 >1W93-A nrPDB Length = 553 Score = 489 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 152/511 (29%), Positives = 241/511 (47%), Gaps = 73/511 (14%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKT-----------VAVHSSADRDLKHVLLADETV 49 ++ KI+IAN G A++ +R+ ++ +T +A + + +++ +AD+ + Sbjct: 45 VISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYI 104 Query: 50 CIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVE--RSGFIFIGPKA 107 + + +Y N+ I+ AE A+ G+G SEN E++ + IFIGP Sbjct: 105 EVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPG 164 Query: 108 ETIRLMGDKVSAIAAMKKAGVPCVPGSDGPL-----------------------GDDMDK 144 +R +GDK+S+ + A VPC+P S + + Sbjct: 165 NAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPED 224 Query: 145 NRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYL 204 AKRIG+PV+IKAS GGGG+G+R V + + E +++ K Sbjct: 225 GLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANE----IPGSPIFIMKLA 280 Query: 205 ENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKAC 264 RH+E+Q+LAD G I L RDCS+QRRHQK++EEAP E + + + Sbjct: 281 GRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLG 340 Query: 265 VDIGYRGAGTFEFLF--ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLS 322 +GY AGT E+L+ ++G+FYF+E+N R+QVEHP TEM++GV+L QL+IA G P+ Sbjct: 341 KLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMH 400 Query: 323 -----------------------------IKQEEVHVRGHAVECRINAEDPNT-FLPSPG 352 KQ +GH CRI +EDPN F PS G Sbjct: 401 RISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGG 460 Query: 353 KITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIID 412 + + V + + + DS G + +GENR + M AL+EL I Sbjct: 461 TLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIR 520 Query: 413 G-IKTNVDLQIRIMNDENFQHGGTNIHYLEK 442 G +T V+ I+++ E+F+ +L+ Sbjct: 521 GDFRTTVEYLIKLLETEDFEDNTITTGWLDD 551 >5MLK-A nrPDB Length = 614 Score = 483 bits (1243), Expect = e-137, Method: Composition-based stats. Identities = 199/448 (44%), Positives = 288/448 (64%), Gaps = 8/448 (1%) Query: 2 LDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL 61 + K+++ANRGEIA+R++RA ++ G+ +VAV++ D + HV LADE +G S +SYL Sbjct: 26 ISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFALGGQTSAESYL 85 Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 + I+ AA +GA AIHPGYGFL+ENA+FA+ V +G I+IGP ++IR +GDKV+A Sbjct: 86 DFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARH 145 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 +A P VPG+ P+ D+ A A+ G P+ IKA+ GGGG+GM+V R E+ + Sbjct: 146 IAARAQAPLVPGTPDPV-KGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPEL 204 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 EA AAF Y+E+YL+ PRHVE QV+AD GN + RDCS+QRR+QK+VE Sbjct: 205 YESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQRRYQKLVE 264 Query: 242 EAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVT 300 EAPAP +T R+ I + + C + Y GAGT E+L ++G F+E+NTR+QVEHPVT Sbjct: 265 EAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVNTRLQVEHPVT 324 Query: 301 EMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAED-PNTFLPSPGKITRFHA 359 E G+DL+ +Q RIA G+ L I ++ RGHA+E RIN ED FLP+PG +T+FH Sbjct: 325 EETAGIDLVLQQFRIANGEKLDITEDPT-PRGHAIEFRINGEDAGRNFLPAPGPVTKFHP 383 Query: 360 PGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNVD 419 P G GVR +S + G + +DSM+ KLI +G +R A+AR + AL E ++G+ T + Sbjct: 384 PSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFGVEGLATVIP 443 Query: 420 LQIRIMNDENFQ--HGGTNIH--YLEKK 443 +++D F G ++H ++E + Sbjct: 444 FHRAVVSDPAFIGDANGFSVHTRWIETE 471 >5H80-A nrPDB Length = 494 Score = 476 bits (1224), Expect = e-134, Method: Composition-based stats. Identities = 178/460 (38%), Positives = 266/460 (57%), Gaps = 23/460 (5%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M +++IANRGE+A+RI RA LG ++VAV++ D HV ADE V + +Y Sbjct: 31 MTPRVLIANRGEVAVRIERAVSALGWQSVAVYAPDDAGSLHVRRADEAVALS-GRGAAAY 89 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L+ A++ A+ A +HPGYGFLSENA+FA ++G +F+GP +T+ L GDK A Sbjct: 90 LDGAALLRVAQEHAATHVHPGYGFLSENADFARACAQAGLVFVGPDPDTLDLFGDKSRAR 149 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAK-RIGYPVIIKASGGGGGRGMRVVRGDAELA 179 ++ GVP +PG+DG +++ A + + G PV++KA GGGGRGMRVVR +LA Sbjct: 150 GLAQRLGVPVIPGTDG--ATTLEEAAAFMQAQGGAPVMLKACSGGGGRGMRVVRQAGDLA 207 Query: 180 QSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKV 239 + EA+ A +Y E+ +E RH+E+QV DGQ + +L ERDC++QRRHQK+ Sbjct: 208 AAFEQASREARLAVGQGDLYAERLIERARHIEVQVAGDGQ-SVTHLWERDCTVQRRHQKL 266 Query: 240 VEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHP 298 +E APAP + +R + + ++ YR GTFEFL G+FYFIE N R+QVEH Sbjct: 267 LEFAPAPHLPQAVRTALIGAALQLAQEVKYRCLGTFEFLVTPGGDFYFIEANPRLQVEHT 326 Query: 299 VTEMITGVDLIKEQLRIAAGQPLSI------KQEEVHVRGHAVECRINAE----DPNTFL 348 VTE G DL+ QLR+AAG+ L+ + G AV+ R+N E D + Sbjct: 327 VTEEWCGTDLVTAQLRLAAGETLTAVGLATQPADAAPPPGQAVQARVNMETLGADGQVHV 386 Query: 349 PSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIA----RMKN 404 G++ F PGG GVR ++ + G T P YD+++ K++ + RD A+ + Sbjct: 387 -GGGQVQTFTPPGGPGVRVDTFVTTGLTPSPQYDALLAKVVVH--RRDAALPGLLRQAAT 443 Query: 405 ALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKL 444 AL E I G+ TN+ +++ + QH + H+L+++L Sbjct: 444 ALSEFQIAGVSTNLAFLQALLHHPDVQHYELSTHWLDERL 483 >5KS8-A nrPDB Length = 405 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 173/443 (39%), Positives = 244/443 (55%), Gaps = 71/443 (16%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 M+ KI+IANRGEIA+RI+RAC E+GIK+VA++S ADR HV ADE IG P + Y Sbjct: 1 MIKKILIANRGEIAVRIVRACSEMGIKSVAIYSDADRHALHVKKADEAYNIGSDPVLG-Y 59 Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 LN I++ A +G A+HP G+ F+ E + Sbjct: 60 LNAHNIVNLAVASGCDALHP------------------GYGFLSENPELAEIC------- 94 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 + G+ + G +V+R + Q Sbjct: 95 ---ARRGIKFI----------------------------------GPDAKVIRQMGDKIQ 117 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 + + + V NPRH+E+QVLAD GN I+L ERDCS+QRR+QK++ Sbjct: 118 ARTAMIKAGIPCVGSSGVV------NPRHIEVQVLADSHGNVIHLFERDCSIQRRNQKLI 171 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPV 299 E AP+P ++ R YIG KA +GY+ AGT EFL + + FYF+EMNTR+QVEH V Sbjct: 172 EIAPSPQLSKAQREYIGNLAVKAAKAVGYKNAGTVEFLLDSDNNFYFMEMNTRLQVEHTV 231 Query: 300 TEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNT-FLPSPGKITRFH 358 TE ITG+D+++EQ+R+A GQ L KQ EV RG A+E RINAEDP FLPS GKITR++ Sbjct: 232 TEQITGIDIVQEQIRVADGQRLQYKQSEVQYRGFAMEFRINAEDPKNDFLPSFGKITRYY 291 Query: 359 APGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIKTNV 418 APGG G+R ++ +Y+GY +PPYYDSM KL + N + + R + AL + ++ G+KT + Sbjct: 292 APGGPGIRMDAAMYSGYVIPPYYDSMCAKLTVWALNWESVVERGRRALNDTVVYGVKTTI 351 Query: 419 DLQIRIMNDENFQHGGTNIHYLE 441 I+ +F++ N ++E Sbjct: 352 PYYQEILKHPDFRNAIFNTSFVE 374 >2YW2-A nrPDB Length = 424 Score = 234 bits (596), Expect = 8e-62, Method: Composition-based stats. Identities = 80/380 (21%), Positives = 143/380 (37%), Gaps = 48/380 (12%) Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 ++ + A+ G G ++ E+ G GP E +L G K A Sbjct: 50 DVEKLAEFAKNEGVDFTIVGPEAPLVEG-IVDEFEKRGLKIFGPNKEAAKLEGSKAFAKT 108 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 MKK G+P + + D +K + +++G P+++KA G G+G V + ++ Sbjct: 109 FMKKYGIPT---ARYEVFTDFEKAKEYVEKVGAPIVVKADGLAAGKGAVVCETVEKAIET 165 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 + + S++ V +E++LE I V+ +G +D H+++++ Sbjct: 166 LDRFLNKKIFGKSSERVVIEEFLEGEEASYI-VMINGDRYVPLPTSQD------HKRLLD 218 Query: 242 E------------APAPGITPE----LRRYIGERCAKACVDIG--YRGAGTFEFLFENGE 283 E +P P I E +R I ER K + G YRG + Sbjct: 219 EDKGPNTGGMGAYSPTPVINEEVEKRIREEIVERVIKGLKEEGIYYRGFLYAGLMITKEG 278 Query: 284 FYFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAE 342 +E N R+ E M D ++ L G+ + IK++E + + R E Sbjct: 279 PKVLEFNVRLGDPEAQPILMRVKNDFLETLLNFYEGKDVHIKEDERYALDVVLASRGYPE 338 Query: 343 DPNT--------FLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGEN 394 P T +L S + FHA G + +G V + YG+ Sbjct: 339 KPETGKIIHGLDYLKSMEDVVVFHA--GTKKEGNFTVTSGGRV--------LNVCAYGKT 388 Query: 395 RDVAIARMKNALQELIIDGI 414 A R A++ + +G+ Sbjct: 389 LKEAKERAYEAIRYVCFEGM 408 >3AW8-A nrPDB Length = 369 Score = 221 bits (562), Expect = 6e-58, Method: Composition-based stats. Identities = 64/292 (21%), Positives = 111/292 (38%), Gaps = 29/292 (9%) Query: 57 VKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDK 116 V +L+ A++ AE V Y F + A ++E G + + P A+ + + D+ Sbjct: 44 VGEFLDEGALLRFAEGLALVT----YEFENVPVEAARRLE--GRLPLYPPAKALEVAQDR 97 Query: 117 VSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGD 175 + + GVP P +D+++ KR+G P ++K GG G+G +VR + Sbjct: 98 LREKTFFQGLGVPTPPFHPVDGPEDLEEGL---KRVGLPALLKTRRGGYDGKGQALVRTE 154 Query: 176 AELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRR 235 E +++ A + +E ++ R V + + G + ++ R Sbjct: 155 EEALEALK--------ALGGRGLILEGFVPFDREVSLLAVRGRTGEVAFYP----LVENR 202 Query: 236 HQKVV---EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTR 292 H + APAPG + L++ +A + Y G EF E F EM R Sbjct: 203 HWGGILRLSLAPAPGASEALQKKAEAYALRAMEALDYVGVLALEFFQVGEELLFNEMAPR 262 Query: 293 IQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDP 344 + T + LR G PL RG + + E P Sbjct: 263 VHNSGHWTIEGAETSQFENHLRAVLGLPLG----STAPRGQSAMVNLIGEKP 310 >4C5A-A nrPDB Length = 330 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 51/225 (22%), Positives = 89/225 (39%), Gaps = 20/225 (8%) Query: 76 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSD 135 +A+H G G E+ +E G + G L DK+ + + AG+P P Sbjct: 84 IALH-GRG--GEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVA 140 Query: 136 GPLGDD----MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKA 191 + DK A +G PVI+K S G GM V + L ++ + Sbjct: 141 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH--- 197 Query: 192 AFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAPG 247 ++ V +EK+L P + +L + +I + + + +E PA G Sbjct: 198 ---DEEVLIEKWLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-G 252 Query: 248 ITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 + + KA +G +G G + + + +G+FY +E NT Sbjct: 253 LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 297 >3ORR-A nrPDB Length = 377 Score = 169 bits (427), Expect = 3e-42, Method: Composition-based stats. Identities = 70/330 (21%), Positives = 121/330 (36%), Gaps = 41/330 (12%) Query: 19 RACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAI 78 ++ +++G K V + S D ++V A E + Y + A+ + + Sbjct: 29 QSAQKMGYKVVVLDPSEDCPCRYV--AHEFI-------QAKYDDEKALNQLGQKCDVIT- 78 Query: 79 HPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPL 138 Y F + +A + + I G + I+L+ D+++ +K AG VP Sbjct: 79 ---YEFENISAQQLKLLCEKYNIPQG--YQAIQLLQDRLTEKETLKSAGTKVVPFISVKE 133 Query: 139 GDDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDM 197 D+DK + +GYP I+K GG G+G ++ + +L + + A Sbjct: 134 STDIDKA---IETLGYPFIVKTRFGGYDGKGQVLINNEKDLQEGFKLIETSECVA----- 185 Query: 198 VYMEKYLENPRHVEIQVLADGQGNAIY---LAERDCSMQRRHQKVVEEAPAPGITPELRR 254 EKYL + V + V G N I L E + Q + +V PA + Sbjct: 186 ---EKYLNIKKEVSLTV-TRGNNNQITFFPLQENEHRNQILFKTIV---PARI---DKTA 235 Query: 255 YIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQL 313 E+ K I + G T EF + N + Y E+ R + + Sbjct: 236 EAKEQVNKIIQSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSGHYSIEACDYSQFDTHI 295 Query: 314 RIAAGQPLSIKQEEVHVRGHAVECRINAED 343 GQ L E + AV + +D Sbjct: 296 LAVTGQSLPNSIELLKP---AVMMNLLGKD 322 >2XD4-A nrPDB Length = 422 Score = 167 bits (424), Expect = 6e-42, Method: Composition-based stats. Identities = 68/349 (19%), Positives = 123/349 (35%), Gaps = 45/349 (12%) Query: 91 FAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAK 150 ++ E++G GP + G K A MKK +P ++ D+ +A + Sbjct: 78 LVDEFEKAGLHVFGPSKAAAIIEGSKQFAKDLMKKYDIPT---AEYETFTSFDEAKAYVQ 134 Query: 151 RIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHV 210 G P++IKA G G+G+ V + E + + K ++ V +E+YL Sbjct: 135 EKGAPIVIKADGLAAGKGVTVAMTEEEAIACLHDFLEDEKFGDASASVVIEEYLSGE--- 191 Query: 211 EIQVLADGQGNAIYLAERDCSMQRRHQKVVE------------EAPAPGITPELRRYIGE 258 E ++A +G +Y + + H++ + +P P I+ E R+ E Sbjct: 192 EFSLMAFVKGEKVY----PMVIAQDHKRAFDGDKGPNTGGMGAYSPVPQISEETVRHAVE 247 Query: 259 R----CAKACVDIGYRGAGTFE--FLFENGEFYFIEMNTRI-QVEHPVTEMITGVDLIKE 311 AKA V G G + IE N R E V DL++ Sbjct: 248 TIVKPAAKAMVQEGRSFTGVLYAGLMLTENGSKVIEFNARFGDPETQVVLPRMESDLVQV 307 Query: 312 QLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLP------SPGKITRFHAPGGFGV 365 L + + + ++ ++ + E P ++ FHA G Sbjct: 308 LLDLLDDKEVDLRWKDTAAVSVVLASEGYPESYAKGTPIGSLAAETEQVVVFHA--GTKA 365 Query: 366 RWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGI 414 + G V + + E + A R+ A+ E+ G+ Sbjct: 366 EGGEFVTNGGRV--------ANVTAFDETFEAARDRVYKAVDEIFKPGL 406 >2YS6-A nrPDB Length = 451 Score = 164 bits (414), Expect = 1e-40, Method: Composition-based stats. Identities = 61/300 (20%), Positives = 109/300 (36%), Gaps = 30/300 (10%) Query: 61 LNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI 120 L+I A++ A+ G + ++ G GP + G K A Sbjct: 70 LDIEALVQFAKQQAIDLTIVGPE-APLASGIVDRFMAEGLRIFGPSQRAALIEGSKAFAK 128 Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQ 180 MKK G+P +D ++ +A ++ G P++IKA G G+G+ V + E Sbjct: 129 ELMKKYGIPT---ADHAAFTSYEEAKAYIEQKGAPIVIKADGLAAGKGVTVAQTVEEALA 185 Query: 181 SISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV 240 + + + + V +E+YLE E +A G +Y ++ + H++ Sbjct: 186 AAKAALVDGQFGTAGSQVVIEEYLEGE---EFSFMAFVNGEKVY----PLAIAQDHKRAY 238 Query: 241 E------------EAPAPGITPELRRYIGER----CAKACVDIG--YRGAGTFEFLFENG 282 + +P P I+ E+ E AKA G + G + Sbjct: 239 DGDEGPNTGGMGAYSPVPQISDEMMDAALEAILRPAAKALAAEGRPFLGVLYAGLMATAN 298 Query: 283 EFYFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINA 341 IE N R E V DL++ L + G+ L ++ + V G + + Sbjct: 299 GPKVIEFNARFGDPEAQVVLPRLKTDLVEAVLAVMDGKELELEWTDEAVLGVVLAAKGYP 358 >3MJF-A nrPDB Length = 431 Score = 138 bits (348), Expect = 4e-33, Method: Composition-based stats. Identities = 57/352 (16%), Positives = 117/352 (33%), Gaps = 48/352 (13%) Query: 22 KELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYL--NIPAIISAAEITGAVAIH 79 +E + A S D +V + + P +I +++ A+ Sbjct: 14 REHALGWKAAQSPL-ADKIYVAPGNAGTALEPTLENVDIAATDIAGLLAFAQSHDI---- 68 Query: 80 PGYGFLSENANFA------EQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG 133 G + +G GP +L G K + + +P Sbjct: 69 ---GLTIVGPEAPLVIGVVDAFRAAGLAIFGPTQAAAQLEGSKAFTKDFLARHNIPS--- 122 Query: 134 SDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAF 193 ++ D++ A ++ G P++IKA G G+G+ V E +++ A Sbjct: 123 AEYQNFTDVEAALAYVRQKGAPIVIKADGLAAGKGVIVAMTQEEAETAVNDMLAGNAFGD 182 Query: 194 SNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE------------ 241 + + +E++L+ V+ DG+ +D H++V + Sbjct: 183 AGHRIVVEEFLDGEEA-SFIVMVDGENVLPMATSQD------HKRVGDGDTGPNTGGMGA 235 Query: 242 EAPAPGITPELRRYIGERC----AKACVDIG--YRGAGTFEFLFE-NGEFYFIEMNTRI- 293 +PAP +T ++ + + ++ + G Y G + +G+ IE N R Sbjct: 236 YSPAPVVTDDVHQRVMDQVIWPTVRGMAAEGNIYTGFLYAGLMISADGQPKVIEFNCRFG 295 Query: 294 QVEHPVTEMITGVDLIKEQLRIAAGQ--PLSIKQEEVHVRGHAVECRINAED 343 E + DL++ L G+ + +E G + D Sbjct: 296 DPETQPIMLRMRSDLVELCLAGTQGKLNEKTSDWDERPSLGVVLAAGGYPAD 347 >1GSO-A nrPDB Length = 431 Score = 135 bits (340), Expect = 4e-32, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 106/307 (34%), Gaps = 33/307 (10%) Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 +IPA++ A+ G + +G GP A +L G K Sbjct: 54 DIPALLDFAQNEKIDLTIVGPEAPLVKG-VVDTFRAAGLKIFGPTAGAAQLEGSKAFTKD 112 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 + + +P ++ +++ A + G P++IKA G G+G+ V E + Sbjct: 113 FLARHKIPT---AEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMTLEEAEAA 169 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 + A + + +E++L+ V+ DG+ +D H++V + Sbjct: 170 VHDMLAGNAFGDAGHRIVIEEFLDGEEA-SFIVMVDGEHVLPMATSQD------HKRVGD 222 Query: 242 ------------EAPAPGITPELRRYIGERC----AKACVDIG--YRGAGTFEFLFE-NG 282 +PAP +T ++ + ER K G Y G + + G Sbjct: 223 KDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMIDKQG 282 Query: 283 EFYFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAAGQ--PLSIKQEEVHVRGHAVECRI 339 IE N R +E + DL++ L + + + +E G + Sbjct: 283 NPKVIEFNCRFGDLETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGVVMAAGG 342 Query: 340 NAEDPNT 346 D T Sbjct: 343 YPGDYRT 349 >2IP4-A nrPDB Length = 417 Score = 130 bits (326), Expect = 2e-30, Method: Composition-based stats. Identities = 68/326 (20%), Positives = 116/326 (35%), Gaps = 44/326 (13%) Query: 62 NIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIA 121 ++ A+ A G G A+ + G + GP + + G K A Sbjct: 49 DVEALADWALAEGIDLTLVGPEAPLVEG-IADAFQARGLLLFGPTQKAAMIEGSKAFAKG 107 Query: 122 AMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 M++ G+P + + + + A + +G PV++K SG G+G+ V + Q+ Sbjct: 108 LMERYGIPT---ARYRVFREPLEALAYLEEVGVPVVVKDSGLAAGKGVTVAFDLHQAKQA 164 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE 241 ++ A+ V +E+YLE + L DG+ L +D H+++++ Sbjct: 165 VANILNRAE----GGEVVVEEYLEGEEAT-VLALTDGETILPLLPSQD------HKRLLD 213 Query: 242 ------------EAPAPGITPELRR---YIGERCAKACVDIG--YRGAGTFEFLFENGEF 284 AP P LRR I + G YRG + Sbjct: 214 GDQGPMTGGMGAVAPYPMDEATLRRVEEEILGPLVRGLRAEGVVYRGVVYAGLMLTREGP 273 Query: 285 YFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAAGQ----PLSIKQEEVHVRGHAVECRI 339 +E N R E + DL++ LR+A G+ LS K+ + Sbjct: 274 KVLEFNARFGDPEAQALLPLLENDLVELALRVAEGRLAGTRLSWKEGAAAC--VVLAAPG 331 Query: 340 NAEDPNTFLP-----SPGKITRFHAP 360 E P +P P + FHA Sbjct: 332 YPESPRKGIPLHVPEPPEGVLVFHAG 357 >5BPF-A nrPDB Length = 306 Score = 127 bits (318), Expect = 1e-29, Method: Composition-based stats. Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 22/226 (9%) Query: 76 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSD 135 +A+H G G E+ +E + G L DK+ + G+P P Sbjct: 60 IALH-GRG--GEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVA 116 Query: 136 GPLGDDM----DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKA 191 ++ A ++G P+I+K S G GM V +EL +++ Sbjct: 117 LNRQQFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKAL-------VE 169 Query: 192 AFSND-MVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAP 246 AF +D V +EK+L P + +L D +I + + + ++ P+ Sbjct: 170 AFQHDSDVLIEKWLSGPEFT-VAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPS- 227 Query: 247 GITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 G++ E + + +A + G G + + + +G FY +E+NT Sbjct: 228 GLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNT 273 >3QFF-A nrPDB Length = 389 Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 131/340 (38%), Gaps = 38/340 (11%) Query: 20 ACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIH 79 A KE+G K + ++ +AD + V SY ++ AI AEI+ V Sbjct: 32 AAKEMGYKIAVL--DPTKNSPCAQVADIEI-------VASYDDLKAIQHLAEISDVVT-- 80 Query: 80 PGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLG 139 Y F + + + +E+ ++ G ++ + ++ + A++KAG+P + L Sbjct: 81 --YEFENIDYRCLQWLEKHAYLPQG--SQLLSKTQNRFTEKNAIEKAGLPV---ATYRLV 133 Query: 140 DDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMV 198 + ++ + YP ++K + GG G+G V+R +A++ ++ + A Sbjct: 134 QNQEQLTEAIAELSYPSVLKTTTGGYDGKGQVVLRSEADVDEARKLANA--------AEC 185 Query: 199 YMEKYLENPRHVEIQVLADGQGN--AIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYI 256 +EK++ + V + V+ G +AE H+ +V PA IT EL + Sbjct: 186 ILEKWVPFEKEVSVIVIRSVSGETKVFPVAENIHVNNILHESIV---PAR-ITEELSQKA 241 Query: 257 GERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRI 315 ++ G E +GE Y E+ R T+ + +R Sbjct: 242 IAYAKVLADELELVGTLAVEMFATADGEIYINELAPRPHNSGHYTQDACETSQFGQHIRA 301 Query: 316 AAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKIT 355 PL E ++ V I E L ++T Sbjct: 302 ICNLPLG----ETNLLKPVVMVNILGEHIEGVLRQVNRLT 337 >5VEV-A nrPDB Length = 431 Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats. Identities = 67/355 (18%), Positives = 117/355 (32%), Gaps = 47/355 (13%) Query: 89 ANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAI 148 A + +G GP +L K A A M K +P + ++ D Sbjct: 84 AGIVDDFRAAGLKIFGPTQYAAQLESSKDFAKAFMVKYNIPT---AQYQTFENADAAHDY 140 Query: 149 AKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR 208 + G P++IKA G G+G+ V E +I K + + V +E +L+ Sbjct: 141 VNQKGAPIVIKADGLVAGKGVIVAMTLDEAHAAIDDMLLGNKMGNAGERVVIEDFLQGEE 200 Query: 209 HVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE------------EAPAPGITPELRRYI 256 V+ DG +D H+++++ +PAP +TP + Sbjct: 201 A-SFIVMVDGNHVLPMATSQD------HKRLLDGDKGPNTGGMGAYSPAPVVTPAVYERA 253 Query: 257 GERC----AKACVDIG--YRGAGTFEFLFEN-GEFYFIEMNTRI-QVEHPVTEMITGVDL 308 G + G + + G Y IE N R E DL Sbjct: 254 MNEIILPTVAGMKAEGHEFTGFLYAGLMIDQSGAPYTIEFNCRFGDPETQPIMSRLNSDL 313 Query: 309 IKEQLRIAAGQPLSIKQE--EVHVRGHAVECRINAEDPN--TFLPSPGKITR----FHAP 360 G+ S+K E G + + E P + + R FHA Sbjct: 314 ADLVEAAIDGRLDSVKAEWNPQTAVGVVLAAQNYPETPKKGDVISGLDDVNRIGKVFHAG 373 Query: 361 GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQELIIDGIK 415 + + G + ++ G++ A A+ AL+++ DG++ Sbjct: 374 TTVNEKGDVLTNGGRILC---------VVGLGDDVAQAKAKAYGALEKISFDGMQ 419 >3AX6-A nrPDB Length = 380 Score = 120 bits (302), Expect = 9e-28, Method: Composition-based stats. Identities = 68/395 (17%), Positives = 135/395 (34%), Gaps = 48/395 (12%) Query: 21 CKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHP 80 K++G + +ADE + G + + I + + Sbjct: 20 AKKMG--FYVIVLDPTPRSPAGQVADEQIVAG-------FFDSERIEDLVKGSDVTT--- 67 Query: 81 GYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGD 140 Y + +++ G+ I P T+ ++ DK +KK G+P + L Sbjct: 68 -YDLEHIDVQTLKKLYNEGYK-IHPSPYTLEIIQDKFVQKEFLKKNGIPV---PEYKLVK 122 Query: 141 DMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVY 199 D++ + + G+PV+ KA GG GRG+ +++ + +L +I Y Sbjct: 123 DLE---SDVREFGFPVVQKARKGGYDGRGVFIIKNEKDLENAIK------------GETY 167 Query: 200 MEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE--EAPAPGITPELRRYIG 257 +E+++E + + + V + +G + + + APA I + + Sbjct: 168 LEEFVEIEKELAVMVARNEKGEIACYPVVEMYFDEDA-NICDTVIAPAR-IEEKYSKIAR 225 Query: 258 ERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIA 316 E + G E FL + GE E+ R T ++ +R Sbjct: 226 EIATSVVEALEGVGIFGIEMFLTKQGEILVNEIAPRPHNSGHYTIEACVTSQFEQHIRAI 285 Query: 317 AGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYT 376 PL + + AV + E+ P+ + A G + H Y Sbjct: 286 MNLPLGSTELLIP----AVMVNLLGEEGYYGKPALIGLEEALAIEGLSL----HFYGKKE 337 Query: 377 VPPYYDSMIGKLICYGENRDVAIARMKNALQELII 411 PY +G + + A+ + A + L + Sbjct: 338 TRPY--RKMGHFTVVDRDVERALEKALRAKKILKV 370 >2QK4-A nrPDB Length = 452 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 58/340 (17%), Positives = 109/340 (32%), Gaps = 49/340 (14%) Query: 95 VERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGY 154 + +G GP AE +L K A M + G+P ++ + + Sbjct: 108 LRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQW---KAFTKPEEACSFILSADF 164 Query: 155 P-VIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQ 213 P +++KASG G+G+ V + E +++ E + + + +E+ L+ E+ Sbjct: 165 PALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGE---EVS 221 Query: 214 VLADGQGNAIYLAERDCSMQRRHQKVVE------------EAPAPGITPELRRYIGERCA 261 L G + + H++++E PAP ++ +L I + Sbjct: 222 CLCFTDGKTVAPMPP----AQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVL 277 Query: 262 K----ACVDIG--YRGAGTFEFLFENGEFYFIEMNTRI-QVEHPVTEMITGVDLIKEQLR 314 + G Y G + +E N R E V + DL + Sbjct: 278 QRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQS 337 Query: 315 IAAGQ---PLSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHI 371 G L + E + + P + IT F G+ Sbjct: 338 TLDGLLCTSLPVWLENHTALTVVMASKGY---PGDYTKGVE-ITGFPEAQALGLEVFHAG 393 Query: 372 YAGYTVPPYYDSMIGKLICYGEN---RDVAIARMKNALQE 408 A GK++ +G + +AL+E Sbjct: 394 TALKN---------GKVVTHGGRVLAVTAIRENLISALEE 424 >4IZO-A nrPDB Length = 419 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 55/316 (17%), Positives = 100/316 (31%), Gaps = 32/316 (10%) Query: 20 ACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIH 79 A + +G + + D +AD+ + +Y + A+ A++ AV+ Sbjct: 53 AAQAMGYRVAVL--DPDPTSPAGAVADKHL-------RAAYDDEAALAELAQLCDAVST- 102 Query: 80 PGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLG 139 F + A + + +S F+ P + + D+++ + +GVP P Sbjct: 103 ---EFENVPAASLDFLAQS--TFVAPAGRCVAIAQDRIAEKRFIAASGVPVAPHVVIESA 157 Query: 140 DDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMV 198 + P I+K + G G+G V E + + Sbjct: 158 AQLAALADADLAAVLPGILKTARLGYDGKGQVRVATAQEARDAY--------GSLGGVPC 209 Query: 199 YMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV---EEAPAPGITPELRRY 255 +EK L V + G + Q H + PAP + L R Sbjct: 210 VLEKRLPLKYEVSALIARGANGASAVFP----LAQNTHHGGILSLSVVPAPAASDALVRD 265 Query: 256 IGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLR 314 + A+ + Y G EF E+G EM R T ++Q+R Sbjct: 266 AQQAAARIADSLDYVGVLCVEFFVLEDGSLVANEMAPRPHNSGHYTVDACETSQFEQQVR 325 Query: 315 IAAGQPLSIKQEEVHV 330 PL ++ Sbjct: 326 AMTRLPLGSTRQHSPA 341 >4MAM-A nrPDB Length = 373 Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats. Identities = 44/241 (18%), Positives = 88/241 (36%), Gaps = 15/241 (6%) Query: 84 FLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMD 143 F +EN + + + + P A+ I + D++ + M+ G+ + D + Sbjct: 66 FENENISHELIKAINHEVSVYPSAKAIAISQDRLLEKSFMQDHGIATAKFVN---IDSLA 122 Query: 144 KNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEK 202 K ++ G P I+K G G+G V+R ++ ++ + + + D + E Sbjct: 123 KLQSAVDDHGLPAILKTRRFGYDGKGQFVIRSQEDITKAWDVLK------DAPDGLIYEA 176 Query: 203 YLENPRHVEIQVLADGQGNAIYLAERDCSMQRRH-QKVVEEAPAPGITPELRRYIGERCA 261 +++ V AD +GN + + H Q ++ E+ AP L + Sbjct: 177 FVDFDYEVSQICTADLKGNIAFYP----LARNTHKQGIIVESEAPFENVVLAEKAQQIAK 232 Query: 262 KACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPL 321 + Y G EF + E E+ R+ + + +R AG L Sbjct: 233 ILVKEFAYVGTLAIEFFVKGDELIVNEIAPRVHNSGHWSIDGAVTSQFENHVRAIAGLIL 292 Query: 322 S 322 Sbjct: 293 G 293 >3VPD-A nrPDB Length = 281 Score = 111 bits (278), Expect = 6e-25, Method: Composition-based stats. Identities = 53/227 (23%), Positives = 85/227 (37%), Gaps = 17/227 (7%) Query: 91 FAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAK 150 A + G + + E I GDK + A+ KAG+P L D ++ + + Sbjct: 65 AARYLTALGIPVVN-RPEVIEACGDKWATSVALAKAGLP---QPKTALATDREEALRLME 120 Query: 151 RIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RH 209 GYPV++K G GR + V A + E F + + Y+++Y+E P R Sbjct: 121 AFGYPVVLKPVIGSWGRLLAKVTDRAAAEALLE--HKEVLGGFQHQLFYIQEYVEKPGRD 178 Query: 210 VEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGY 269 + + V+ + AIY E P L I A +G Sbjct: 179 IRVFVVGERAIAAIYRRSAHWITNTARGGQAENCP-------LTEEIARLSVGAAEAVG- 230 Query: 270 RGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIA 316 G + E+N ++ ++ V TGVD+ E LR A Sbjct: 231 GGVVAVDLFESERGLLVNEVNHTMEFKNSV--HTTGVDIPGEILRYA 275 >4EGJ-A nrPDB Length = 334 Score = 111 bits (277), Expect = 8e-25, Method: Composition-based stats. Identities = 43/224 (19%), Positives = 83/224 (37%), Gaps = 16/224 (7%) Query: 74 GAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG 133 A+H GYG EN ++ G + G L DK ++ G+P P Sbjct: 86 AFNALHGGYG---ENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQLGIPTPPF 142 Query: 134 SDGPLGDDMD-KNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAA 192 GDD + + + I ++G P+ +K + G + V+ L ++ Sbjct: 143 EAVLRGDDYEARAKEIVAKLGLPLFVKPASEGSSVAVIKVKSADALPAALIEAVK----- 197 Query: 193 FSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAPGI 248 + +V +EK +E + + I + + + + P G+ Sbjct: 198 -FDRIVVVEKSIEGGGEYTACIAGNLDLPVIRIVPAGEFYDYHAKYIANDTQYLIPC-GL 255 Query: 249 TPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 T + + +A +G G +F+ + +G YF+E+NT Sbjct: 256 TADEEARLKVLARRAFDVLGCTDWGRADFMLDADGNPYFLEVNT 299 >5D8D-A nrPDB Length = 308 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 48/217 (22%), Positives = 77/217 (35%), Gaps = 18/217 (8%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDD 141 +G E+ +E + G + + DKV + + +P P D Sbjct: 66 HGRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITKETD 125 Query: 142 MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYM- 200 +D A +G PVIIK G GM V + A +I A +D V M Sbjct: 126 LDSVIA---ELGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIE-------KATQHDAVVMA 175 Query: 201 EKYLENPRHVEIQVLADGQGNAIYLAERD--CSMQRRHQKV---VEEAPAPGITPELRRY 255 EK++ R I L I L + VE G++ + Sbjct: 176 EKWITG-REFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKK 234 Query: 256 IGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 + C +A +G G G + + + G F+ +E+NT Sbjct: 235 LQALCLRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNT 271 >2CQY-A nrPDB Length = 108 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 42/98 (42%), Positives = 63/98 (64%), Gaps = 1/98 (1%) Query: 114 GDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVR 173 GDK+ + KKA V +PG DG + D ++ IA+ IGYPV+IKAS GGGG+GMR+ Sbjct: 7 GDKIESKLLAKKAEVNTIPGFDGVV-KDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAW 65 Query: 174 GDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVE 211 D E ++ EA ++F +D + +EK+++NPRH+ Sbjct: 66 DDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIS 103 >3LP8-A nrPDB Length = 442 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 58/335 (17%), Positives = 107/335 (31%), Gaps = 27/335 (8%) Query: 91 FAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAK 150 ++ + G + GP RL K + G+P + D + Sbjct: 99 LSDALTEEGILVFGPSKAAARLESSKGFTKELCMRYGIPT---AKYGYFVDTNSAYKFID 155 Query: 151 RIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHV 210 + P+++KA G G+G + E ++ K + + +E++LE + + Sbjct: 156 KHKLPLVVKADGLAQGKGTVICHTHEEAYNAVDAMLVHHKFGEAGCAIIIEEFLEG-KEI 214 Query: 211 EIQVLADGQGNAIYLAERDCSMQRRHQK------VVEEAPAPGITPELRRYIGERC---- 260 L DG I +D + K + + IT E+ I ++ Sbjct: 215 SFFTLVDGSNPVILGVAQDYKTIGDNNKGPNTGGMGSYSKPNIITQEMEHIIIQKIIYPT 274 Query: 261 AKAC--VDIGYRGAGTFEFLFENGEFYFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAA 317 KA ++I +RG + + E +E N R E D +K A Sbjct: 275 IKAMFNMNIQFRGLLFAGIIIKKNEPKLLEYNVRFGDPETQSILPRLNSDFLKLLSLTAK 334 Query: 318 GQ--PLSIKQEEVHVRGHAVECRINA--EDPNTFLPSPGKITRFHAPGGFGVRWESHIYA 373 G+ S++ + V R N+ + I + V+ Sbjct: 335 GKLGNESVELSKKAALCVVVASRGYPGEYKKNSIINGIENIEKL-----PNVQLLHAGTR 389 Query: 374 GYTVPPYYDS-MIGKLICYGENRDVAIARMKNALQ 407 DS + ++ GEN A + AL Sbjct: 390 REGNNWVSDSGRVINVVAQGENLASAKHQAYAALD 424 >4E4T-A nrPDB Length = 419 Score = 108 bits (269), Expect = 5e-24, Method: Composition-based stats. Identities = 58/316 (18%), Positives = 100/316 (31%), Gaps = 32/316 (10%) Query: 20 ACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIH 79 A + +G + + D +AD + +Y + A+ A + AV+ Sbjct: 53 AAQSMGYRVAVL--DPDPASPAGAVADRHL-------RAAYDDEAALAELAGLCEAVST- 102 Query: 80 PGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLG 139 F + A + + R+ F+ P + + D+++ ++ +GVP P Sbjct: 103 ---EFENVPAASLDFLART--TFVAPAGRCVAVAQDRIAEKRFIEASGVPVAPHVVIESA 157 Query: 140 DDMDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMV 198 + A P I+K + G G+G V E +A AA Sbjct: 158 AALAALDDAALDAVLPGILKTARLGYDGKGQVRVSTAREA--------RDAHAALGGVPC 209 Query: 199 YMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV---EEAPAPGITPELRRY 255 +EK L V + G + Q H + PAP Sbjct: 210 VLEKRLPLKYEVSALIARGADGRSAAFP----LAQNVHHNGILALTIVPAPAADTARVEE 265 Query: 256 IGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLR 314 + + +GY G EF E+G F EM R T ++Q+R Sbjct: 266 AQQAAVRIADTLGYVGVLCVEFFVLEDGSFVANEMAPRPHNSGHYTVDACATSQFEQQVR 325 Query: 315 IAAGQPLSIKQEEVHV 330 PL ++ Sbjct: 326 AMTRMPLGNPRQHSPA 341 >3K5H-A nrPDB Length = 403 Score = 108 bits (269), Expect = 6e-24, Method: Composition-based stats. Identities = 47/253 (18%), Positives = 96/253 (37%), Gaps = 16/253 (6%) Query: 103 IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASG 162 I P + IR + +K + ++K G+P + + + + +++GYP+++K+ Sbjct: 111 IEPSWQAIRTIQNKFNQKEHLRKYGIPMAEHRELVENTPAELAK-VGEQLGYPLMLKSKT 169 Query: 163 GG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGN 221 GRG V ++ +++ A + +Y EK+ + + V+ Sbjct: 170 MAYDGRGNFRVNSQDDIPEALE--------ALKDRPLYAEKWAYFKMELAVIVVKTKD-E 220 Query: 222 AIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE-FLFE 280 + + + K+V APA ++ + + E KA +G E FL E Sbjct: 221 VLSYPTVETVQEDSICKLV-YAPARNVSDAINQKAQELARKAVAAFDGKGVFGVEMFLLE 279 Query: 281 NGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRIN 340 + E+ +RI T + LR L I + + +R ++ I Sbjct: 280 DDSIMLCEIASRIHNSGHYTIEGCALSQFDAHLRAI--LDLPIPAQSLEIRQPSIMLNII 337 Query: 341 -AEDPNTFLPSPG 352 P+T L + Sbjct: 338 GGAAPDTHLQAAE 350 >4EG0-A nrPDB Length = 317 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 49/224 (21%), Positives = 83/224 (37%), Gaps = 16/224 (7%) Query: 74 GAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG 133 A+H GYG EN ++ G + G L DK ++ GVP P Sbjct: 69 AFNALHGGYG---ENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGVPTPPF 125 Query: 134 SDGPLGDDM-DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAA 192 GDD + I ++G P+ +K + G + V+ L ++S +AA Sbjct: 126 ETVMRGDDYAARATDIVAKLGLPLFVKPASEGSSVAVLKVKTADALPAALS------EAA 179 Query: 193 FSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAPGI 248 + +V +EK +E + D I + + V + P G+ Sbjct: 180 THDKIVIVEKSIEGGGEYTACIAGDLDLPLIKIVPAGEFYDYHAKYVANDTQYLIPC-GL 238 Query: 249 TPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 E + +A +G G +F+ + G YF+E+NT Sbjct: 239 PAEQETELKRIARRAFDVLGCTDWGRADFMLDAAGNAYFLEVNT 282 >2CZG-A nrPDB Length = 433 Score = 105 bits (263), Expect = 3e-23, Method: Composition-based stats. Identities = 72/426 (16%), Positives = 150/426 (35%), Gaps = 45/426 (10%) Query: 3 DKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLN 62 KI++ GE+ I + LG++ VAV + + +A + V + ++ Sbjct: 20 QKILLLGSGELGKEIAIEAQRLGVEVVAV--DRYANAPAMQVAHRSY-------VGNMMD 70 Query: 63 IPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAA 122 + S E AI P + N + + E+ G+ F+ P A + + Sbjct: 71 KDFLWSVVEREKPDAIIP--EIEAINLDALFEFEKDGY-FVVPNARATWIAMHRERLRET 127 Query: 123 M-KKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQS 181 + K+A VP S +D+ ++IGYP KA G+G V+G ++ ++ Sbjct: 128 LVKEAKVPT---SRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKA 184 Query: 182 ISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLA--DGQGNAIYLAERDC-SMQRRHQK 238 + +A+ + + + +E++++ V + D G + + Q Sbjct: 185 WEEAKTKARGS--AEKIIVEEHIDFDVEVTELAVRHFDENGEIVTTFPKPVGHYQIDGDY 242 Query: 239 VVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHP 298 PA I+ + R + + +G G E + + + E++ R Sbjct: 243 HASWQPA-EISEKAEREVYRIAKRITDVLGGLGIFGVEMFVKGDKVWANEVSPRPHDTGM 301 Query: 299 VTEMI--TGVDLIKEQLRIAAGQPLSIKQEE--------VHVRGHAVECRINAEDPNTFL 348 VT G LR G P+ + + + H ++ +++ P Sbjct: 302 VTLASHPPGFSEFALHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVSGYSPRF-- 359 Query: 349 PSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIAR--MKNAL 406 G + P + + Y +G + + ++ +VA + M + Sbjct: 360 --RGLVKALSVP-------NATVRLFGKPEAYVGRRLGIALAWDKDVEVAKRKAEMVAHM 410 Query: 407 QELIID 412 EL Sbjct: 411 IELRTR 416 >1UC8-A nrPDB Length = 280 Score = 104 bits (260), Expect = 7e-23, Method: Composition-based stats. Identities = 52/227 (22%), Positives = 86/227 (37%), Gaps = 17/227 (7%) Query: 91 FAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAK 150 A + G + + E I GDK + A+ KAG+P L D ++ + + Sbjct: 65 AARYLTALGIPVVN-RPEVIEACGDKWATSVALAKAGLP---QPKTALATDREEALRLME 120 Query: 151 RIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RH 209 GYPV++K G GR + E F + + Y+++Y+E P R Sbjct: 121 AFGYPVVLKPVIGSWGRLL--AXXXXXXXXXXXXXXKEVLGGFQHQLFYIQEYVEKPGRD 178 Query: 210 VEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGY 269 + + V+ + AIY E P +T E+ R KA +G Sbjct: 179 IRVFVVGERAIAAIYRRSAHWITNTARGGQAENCP---LTEEVAR----LSVKAAEAVG- 230 Query: 270 RGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIA 316 G + E+N ++ ++ V TGVD+ E L+ A Sbjct: 231 GGVVAVDLFESERGLLVNEVNHTMEFKNSV--HTTGVDIPGEILKYA 275 >2Z04-A nrPDB Length = 365 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 51/325 (15%), Positives = 99/325 (30%), Gaps = 41/325 (12%) Query: 22 KELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPG 81 ++LG K + + +AD G + +++ II+ Sbjct: 21 RKLGFKFHVL--EDKENAPACRVADRCFRTG---QISEFVDSCDIIT------------- 62 Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDD 141 Y F E+ E P + + + ++ +KK G P L Sbjct: 63 YEFEHIKDEVLEKCESKLI----PNPQALYVKKSRIREKLFLKKHGFPVPEF----LVIK 114 Query: 142 MDKNRAIAKRIGYPVIIKASGGG-GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYM 200 D+ K PV+IKA G G+G ++ + Q + E + Sbjct: 115 RDEIIDALKSFKLPVVIKAEKLGYDGKGQYRIKKLEDANQVVKNHDKEESF-------II 167 Query: 201 EKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERC 260 E++++ + + D +G Y + + + P + + E Sbjct: 168 EEFVKFEAEISCIGVRDREG-KTYFYPQPFNKHEEGILIYNYVPYAKL-----KEAEEIT 221 Query: 261 AKACVDIGYRGAGTFEF-LFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQ 319 + + G T EF L ++G E R+ T + LR Sbjct: 222 KRLMELLDIVGVFTVEFFLLKDGRVLINEFAPRVHNTGHWTLDGAYTSQFENLLRAITEM 281 Query: 320 PLSIKQEEVHVRGHAVECRINAEDP 344 PL + ++ + + E P Sbjct: 282 PLGSTELKLPSGMVNILGKSYEEIP 306 >3R5X-A nrPDB Length = 307 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 37/222 (16%), Positives = 82/222 (36%), Gaps = 18/222 (8%) Query: 74 GAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG 133 +A+H YG E+ +E G + G + + DK + ++ G+ Sbjct: 59 ALLALHGKYG---EDGTVQGTLESLGIPYSGSNMLSSGICMDKNISKKILRYEGIETPDW 115 Query: 134 SDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAF 193 + +D+ N ++G+P+++K + GG G+++V EL + Sbjct: 116 IELTKMEDL--NFDELDKLGFPLVVKPNSGGSSVGVKIVYDKDELISMLETVFE------ 167 Query: 194 SNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQK----VVEEAPAPGIT 249 + V +EKY++ + + Q I + + +EE + Sbjct: 168 WDSEVVIEKYIKGEE-ITCSIFDGKQLPIISIRHAAEFFDYNAKYDDASTIEE--VIELP 224 Query: 250 PELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNT 291 EL+ + + + + + ++G Y +E+NT Sbjct: 225 AELKERVNKASLACYKALKCSVYARVDMMVKDGIPYVMEVNT 266 >1VKZ-A nrPDB Length = 412 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 53/318 (16%), Positives = 102/318 (32%), Gaps = 35/318 (11%) Query: 102 FIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKAS 161 GP E RL G KV A MKK G+ + + ++ R K+ P +IKA Sbjct: 93 VFGPVKEVARLEGSKVYAKRFMKKYGIRTARF---EVAETPEELREKIKKFSPPYVIKAD 149 Query: 162 GGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGN 221 G G+G+ ++ E + S V ++++L + V+ +G+ Sbjct: 150 GLARGKGVLILDSKEETIEKGSKLIIGELIKGVKGPVVIDEFLAGNELSAMAVV-NGRNF 208 Query: 222 AIYLAERDCSMQRRHQKVVE------------EAPAPGITPELR--RYIGERCAKACVDI 267 I RD ++++++ P + ++ + ++ Sbjct: 209 VILPFVRD------YKRLMDGDRGPNTGGMGSWGPVEIPSDTIKKIEELFDKTLWGVEKE 262 Query: 268 G--YRGAGTFEFLFENGEFYFIEMNTRI-QVEHPVTEMITGVDLIKEQLRIAAGQPLSIK 324 G YRG + +G+ Y +E N R+ E V + + L G + Sbjct: 263 GYAYRGFLYLGLMLHDGDPYILEYNVRLGDPETEVIVTLNPEGFVNAVLEGYRGGKMEPV 322 Query: 325 QEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSM 384 + + R + P G + + G V Sbjct: 323 EPRGFAVDVVLAARGYPDAPEKGKEITLPEEGLIFFAGVAEKDGKLVTNGGRV------- 375 Query: 385 IGKLICYGENRDVAIARM 402 + GE ++ A + Sbjct: 376 -LHCMGTGETKEEARRKA 392 >5NRH-A nrPDB Length = 312 Score = 98.6 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 44/224 (19%), Positives = 79/224 (35%), Gaps = 16/224 (7%) Query: 74 GAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG 133 A+H GYG EN ++ G + G L DK ++ G+P P Sbjct: 65 AFNALHGGYG---ENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPF 121 Query: 134 SDGPLGDDM-DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAA 192 GDD + + I ++G P+ +K + G + V+ L ++ Sbjct: 122 ETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKH---- 177 Query: 193 FSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAPGI 248 + +V +EK +E + AD I + + + + P G+ Sbjct: 178 --DKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPC-GL 234 Query: 249 TPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 +A +G G +F+ + G YF+E+NT Sbjct: 235 DAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNT 278 >3I12-A nrPDB Length = 364 Score = 96.7 bits (239), Expect = 2e-20, Method: Composition-based stats. Identities = 59/287 (20%), Positives = 106/287 (36%), Gaps = 28/287 (9%) Query: 24 LGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPA-----IISAAEITG---A 75 LGI D + ++ AD+ I PS S +P +I+A Sbjct: 41 LGIDKAGQWHVNDAEN-YLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTV 99 Query: 76 VAIHP-GYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGS 134 I P +G L E+ + + + F+G + DK A ++ AG+ P Sbjct: 100 DVIFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFI 159 Query: 135 DGPLGDDMDKNRAIAK-RIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAF 193 + + A + R+G P+ +K + G G+ V +A+ Q++++ F Sbjct: 160 TLTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALA-----FEF 214 Query: 194 SNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAE---RDCSMQRRHQKVVE-----EAPA 245 + V +E+ ++ R +E VL + A E + + + PA Sbjct: 215 DH-KVVVEQGIKG-REIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPA 272 Query: 246 PGITPELRRYIGERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNT 291 I E+ I +A +G G + FL + E E+NT Sbjct: 273 -QIPSEVNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINT 318 >2FB9-A nrPDB Length = 322 Score = 96.3 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 49/217 (22%), Positives = 79/217 (36%), Gaps = 20/217 (9%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDD 141 +G E+ +E G ++G L DK + + +AGVP VP G+ Sbjct: 85 HGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEP 144 Query: 142 MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYME 201 + K + G G+ V +L ++++ + A +E Sbjct: 145 PVVPFDPPFFV------KPANTGSSVGISRVERFQDLEAALALAFRYDEKA------VVE 192 Query: 202 KYLENPRHVEIQVLADGQGNAIYLAE---RDCSMQRRHQKVVEEA----PAPGITPELRR 254 K L R +E+ VL + G A + E + A PAP + P + Sbjct: 193 KALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAP-LDPGTQE 251 Query: 255 YIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNT 291 + E KA +G RG +F GE Y E+NT Sbjct: 252 TVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNT 288 >4FU0-A nrPDB Length = 357 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 84/251 (33%), Gaps = 17/251 (6%) Query: 49 VCIGPAPSVKSYLNIPAIISAAEITGAVAIHPG-YGFLSENANFAEQVERSGFIFIGPKA 107 V + SVK +L I + I + P +G E+ E +G +G Sbjct: 74 VVVSQNRSVKGFLEIAS--DKYRIIKVDLVFPVLHGKNGEDGTLQGIFELAGIPVVGCDT 131 Query: 108 ETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGR 167 + L DK A + AG+ ++ + I + YP+ IK G Sbjct: 132 LSSALCMDKDRAHKLVSLAGISVPKSVTFKRFNEEAAMKEIEANLTYPLFIKPVRAGSSF 191 Query: 168 GMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR------HVEIQVLADGQGN 221 G+ V EL +I + + V +E+ + ++ ++ Sbjct: 192 GITKVIEKQELDAAIELAFEH------DTEVIVEETINGFEVGCAVLGIDELIVGRVDEI 245 Query: 222 AIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE- 280 + D + + + PA I E + I E +G G + + Sbjct: 246 ELSSGFFDYTEKYTLKSSKIYMPAR-IDAEAEKRIQEAAVTIYKALGCSGFSRVDMFYTP 304 Query: 281 NGEFYFIEMNT 291 +GE F E+NT Sbjct: 305 SGEIVFNEVNT 315 >1EZ1-A nrPDB Length = 392 Score = 93.2 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 60/341 (17%), Positives = 119/341 (34%), Gaps = 21/341 (6%) Query: 4 KIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNI 63 ++++ GE+ + C+ LG++ +AV AD HV + + L+ Sbjct: 14 RVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVI---------NMLDG 64 Query: 64 PAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKV-SAIAA 122 A+ E+ I P + + Q+E G + P A +L ++ A Sbjct: 65 DALRRVVELEKPHYIVP--EIEAIATDMLIQLEEEGLNVV-PCARATKLTMNREGIRRLA 121 Query: 123 MKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSI 182 ++ +P S D R IGYP I+K G+G +R +LAQ+ Sbjct: 122 AEELQLPT---STYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAW 178 Query: 183 SMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEE 242 + +A V +E ++ + + ++ G ++ Q Sbjct: 179 KYAQQGGRA--GAGRVIVEGVVKFDFEITLLTVSAVDG--VHFCAPVGHRQEDGDYRESW 234 Query: 243 APAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEM 302 P ++P E K + +G G E E F E++ R VT + Sbjct: 235 QP-QQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLI 293 Query: 303 ITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAED 343 + +R G P+ ++ + ++ +++ Sbjct: 294 SQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN 334 >2I87-A nrPDB Length = 364 Score = 92.8 bits (229), Expect = 3e-19, Method: Composition-based stats. Identities = 47/249 (18%), Positives = 87/249 (34%), Gaps = 22/249 (8%) Query: 57 VKSYLNIPAII-SAAEITGAVAIHPG-YGFLSENANFAEQVERSGFIFIGPKAETIRLMG 114 L I ++ ++ A+ P +G E+ E ++G + Sbjct: 69 NGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSM 128 Query: 115 DKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAK----RIGYPVIIKASGGGGGRGMR 170 DK+ + G+P +P + I K ++ YPV +K + G G+ Sbjct: 129 DKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGIS 188 Query: 171 VVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAE--- 227 +AEL + I AF D + + N R +E+ VL + A + E Sbjct: 189 KCNNEAELKEGIKE-------AFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVK 241 Query: 228 ----RDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENG 282 D + + KV + PA + +++ + +A G +F E+ Sbjct: 242 DVAFYDYKSKYKDGKVQLQIPA-DLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDN 300 Query: 283 EFYFIEMNT 291 + Y E N Sbjct: 301 QIYINETNA 309 >4DIM-A nrPDB Length = 403 Score = 91.7 bits (226), Expect = 6e-19, Method: Composition-based stats. Identities = 57/292 (19%), Positives = 105/292 (35%), Gaps = 26/292 (8%) Query: 5 IVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADE--TVCIGPAPSVKSYLN 62 I+ A RG++ L +A KELGI T+A + + + LADE + I V+ + Sbjct: 12 ILGAGRGQLGL--YKAAKELGIHTIA-GTMPNAHKPCLNLADEISYMDISNPDEVEQKV- 67 Query: 63 IPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAA 122 + A G +S A ++ +G E + GDK A Sbjct: 68 KDLNLDGAATCCLDT-----GIVS----LARICDKENL--VGLNEEAAIMCGDKYKMKEA 116 Query: 123 MKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSI 182 KK V + + + ++ + + + PVI+KA+ G +G+ + + + E Sbjct: 117 FKKYNVNT---ARHFVVRNENELKNALENLKLPVIVKATDLQGSKGIYIAKKEEEAIDGF 173 Query: 183 SMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEE 242 E D +E+++E + + + M V Sbjct: 174 ----NETMNLTKRDYCIVEEFIEGYEFGAQAFVYKNDVLFVMPHGDETYMSHTAVPVGHY 229 Query: 243 APAPGITPELRRYIGERCAKACVDIGYRG-AGTFEFLFENGEFYFIEMNTRI 293 P + + E KA +G A + + ++ E Y IE+ R+ Sbjct: 230 VPLDVKDDIIEKTKTE-VKKAIKALGLNNCAVNVDMILKDNEVYIIELTGRV 280 >3VOT-A nrPDB Length = 425 Score = 89.0 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 61/330 (18%), Positives = 126/330 (38%), Gaps = 33/330 (10%) Query: 17 ILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAV 76 I + LG+K ++SA+ ++ + V + + + A + T Sbjct: 20 IFEEAERLGLKVTFFYNSAEDFPGNLPAVERCVPLPL------FEDEEAAMDVVRQTFVE 73 Query: 77 AIHPGYGFLSENA-----NFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCV 131 G L E A AE + G F T+ +K + +++ G+ Sbjct: 74 FPFDGVMTLFEPALPFTAKAAEALNLPGLPFT-----TMENCRNKNKTRSILQQNGLNTP 128 Query: 132 PGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAK- 190 + D++ +++ YP+++K G +G+ V EL +++ A + Sbjct: 129 VFHEFHTLADLEN-----RKLSYPLVVKPVNGFSSQGVVRVDDRKELEEAVRKVEAVNQR 183 Query: 191 ----AAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAP 246 + E++++ P + G + + + + S ++ V APA Sbjct: 184 DLNRFVHGKTGIVAEQFIDGPEFAIETLSIQGNVHVLSIGYKGNSKGPFFEEGVYIAPA- 242 Query: 247 GITPELRRYIGERCAKACVDIG-YRGAGTFEFLFE-NGEFYFIEMNTRI---QVEHPVTE 301 + E R I + A +G ++G E + +G Y IE+ RI V H + + Sbjct: 243 QLKEETRLAIVKEVTGAVSALGIHQGPAHTELRLDKDGTPYVIEVGARIGGSGVSHYIVK 302 Query: 302 MITGVDLIKEQLRIAAGQPLSIKQEEVHVR 331 TG++ ++ L+ A +PL + E +R Sbjct: 303 ESTGINFMQLVLQNAL-KPLESSEFEGEIR 331 >1E4E-B nrPDB Length = 343 Score = 88.6 bits (218), Expect = 4e-18, Method: Composition-based stats. Identities = 58/231 (25%), Positives = 87/231 (37%), Gaps = 30/231 (12%) Query: 76 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSD 135 VA +G E+ + E SG F+G ++ + DK K AG+ P Sbjct: 93 VAFSALHGKSGEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIAT-PAFW 151 Query: 136 GPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSN 195 DD R +A YPV +K + G G++ V EL +I R + Sbjct: 152 VINKDD----RPVAATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQY------D 201 Query: 196 DMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCS-----MQRRHQ-----KVVEEA-- 243 + +E+ + E+ G A+ + E D + R HQ K E A Sbjct: 202 SKILIEQAVSG---CEVGCAVLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVI 258 Query: 244 --PAPGITPELRRYIGERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNT 291 PA ++ E R I E K +G RG + FL + G E+NT Sbjct: 259 TVPA-DLSAEERGRIQETVKKIYKTLGCRGLARVDMFLQDRGRIVLNEVNT 308 >3LWB-A nrPDB Length = 373 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 46/229 (20%), Positives = 82/229 (35%), Gaps = 27/229 (11%) Query: 78 IHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGP 137 +H YG E+ +E +G ++G + DK + G+P + Sbjct: 117 LHGPYG---EDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLR 173 Query: 138 LGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDM 197 +R +R+G PV +K + GG G+ V +L +++ R + Sbjct: 174 PPRST-LHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRH------DPK 226 Query: 198 VYMEKYLENPRHVEIQV--LADGQGNAIYLAE---------RDCSMQRRHQKVVEEA--- 243 V +E + R +E V + DG A L E D + + + A Sbjct: 227 VIVEAAISG-RELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELD 285 Query: 244 -PAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNT 291 PA + ++ I + +A I RG +F + E+NT Sbjct: 286 VPAK-VDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPVINEINT 333 >3K3P-A nrPDB Length = 383 Score = 85.5 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 41/219 (18%), Positives = 88/219 (40%), Gaps = 16/219 (7%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAG-VPCVPGSDGPLGD 140 +G + E+ + +E ++G + + DK++ ++ A +P V G+ Sbjct: 128 HGPMGEDGSIQGFLEVLKMPYVGTNILSSSVAMDKITTNQVLESATTIPQVAYVALIEGE 187 Query: 141 DMDKNRAIAKR-IGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVY 199 ++ A + + YPV +K + G G+ +L Q+I++ + V Sbjct: 188 PLESKLAEVEEKLIYPVFVKPANMGSSVGISKAENRTDLKQAIALALKY------DSRVL 241 Query: 200 MEKYLENPRHVEIQVLADGQGNAIYLAE--RD-CSMQRRHQKV---VEEAPAPGITPELR 253 +E+ ++ R +E+ +L + E +D + + + A I P + Sbjct: 242 IEQGVD-AREIEVGILGNTDVKTTLPGEIVKDVAFYDYEAKYIDNKITMAIPAEIDPVIV 300 Query: 254 RYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNT 291 + + A A +G G +F E+G+ Y E+NT Sbjct: 301 EKMRDYAATAFRTLGCCGLSRCDFFLTEDGKVYLNELNT 339 >3ETH-A nrPDB Length = 355 Score = 84.4 bits (207), Expect = 9e-17, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 74/241 (30%), Gaps = 24/241 (9%) Query: 106 KAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGG- 164 + ++ D+++ K +P P L + + A+ R+G I+K GG Sbjct: 70 NRDVFPIIADRLTQKQLFDKLHLPTAPW---QLLAERSEWPAVFDRLGELAIVKRRTGGY 126 Query: 165 GGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIY 224 GRG +R + E A +E+ + V + G+ ++ Sbjct: 127 DGRGQWRLRANE----------TEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVF 176 Query: 225 LAERDCSMQRRHQKVVEEAPA--PGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENG 282 HQ + P + + E + ++GY G E Sbjct: 177 YP----LTHNLHQDGILRTSVAFPQANAQQQARAEEMLSAIMQELGYVGVMAMECFVTPQ 232 Query: 283 EFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAE 342 E+ R+ T+ + + LR PL + V +V + Sbjct: 233 GLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLP----QPVVNNPSVMINLIGS 288 Query: 343 D 343 D Sbjct: 289 D 289 >3E5N-A nrPDB Length = 386 Score = 79.0 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 78/220 (35%), Gaps = 18/220 (8%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDD 141 +G L E+ + + + F+G + DK A ++ A + P Sbjct: 126 HGTLGEDGSLQGLLRMANLPFVGSGVLGSAVAMDKDMAKRVLRDARLAVAPFVCFDRHTA 185 Query: 142 M-DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYM 200 + ++G P+ +K + G G+ VR + A A A + V + Sbjct: 186 AHADVDTLIAQLGLPLFVKPANQGSSVGVSQVRTAD------AFAAALALALAYDHKVLV 239 Query: 201 EKYLENPRHVEIQVLADGQGNAIYLAE---RDCSMQRRHQKVVEEA-----PAPGITPEL 252 E + R +E VL + +A E D + + E PA I + Sbjct: 240 EAAVAG-REIECAVLGNAVPHASVCGEVVVHDAFYSYATKYISEHGAEIVIPA-DIDAQT 297 Query: 253 RRYIGERCAKACVDIGYRGAGTFE-FLFENGEFYFIEMNT 291 ++ I + +A +G G + FL +G E+NT Sbjct: 298 QQRIQQIAVQAYQALGCAGMARVDVFLCADGRIVINEVNT 337 >2PVP-A nrPDB Length = 367 Score = 76.6 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 48/241 (19%), Positives = 90/241 (37%), Gaps = 22/241 (9%) Query: 58 KSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKV 117 S+L II + +H G G E+ A +E FIGP+ E L +K Sbjct: 98 NSFL-GAKIIELPLVINL--VHGGDG---EDGKLASLLEFYRIAFIGPRIEASVLSYNKY 151 Query: 118 SAIAAMKKAGVPCVPGSDGPLGDDMDKNRAI-AKRIGYPVIIKASGGGGGRGMRVVRGDA 176 K G+ + D L ++ ++ A+ +P I+K S G G+ VV+ + Sbjct: 152 LTKLYAKDLGIKTL---DYVLLNEKNRANALDLMNFNFPFIVKPSNAGSSLGVNVVKEEK 208 Query: 177 ELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQ---VLADGQGNAIYLAERDCSMQ 233 EL ++ +K V +E +++ + + + D + I + + Sbjct: 209 ELIYALDSAFEYSK------EVLIEPFIQGVKEYNLAGCKIKKDFCFSYIEEPNKQEFLD 262 Query: 234 RRHQKV---VEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMN 290 + + + +AP ++ L + E K D+ +F E Y E+N Sbjct: 263 FKQKYLDFSRNKAPKASLSNALEEQLKENFKKLYSDLFDGAIIRCDFFVIENEVYLNEIN 322 Query: 291 T 291 Sbjct: 323 P 323 >6DGI-A nrPDB Length = 337 Score = 76.6 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 44/225 (19%), Positives = 84/225 (37%), Gaps = 25/225 (11%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVP--GSDGPLG 139 +GF E + +E +G ++G E +K+++ +P P Sbjct: 86 HGFPGETGDIQSMLELAGIPYLGCGPEASANSFNKITSKLWYDALDIPNTPYLFLTQNTP 145 Query: 140 DDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVY 199 +DK + G + +KA+ G G V + ++A +I EA F ++ V Sbjct: 146 SSIDKAKQAFGHWGS-IFVKAARQGSSVGCYKVTTEDQIAPAI-----EAAFGF-SEQVL 198 Query: 200 MEKYLENPRHVEIQ-------VLADGQGNAIYLAERDCSMQRR-----HQKVVEEAPAPG 247 +E+ + PR +E+ + G I S + + H + V E A Sbjct: 199 VEQAV-KPRELEVSAYEMNGKLYISKPGEVIAPEGTFYSYEEKYSANSHARTVLE--AEN 255 Query: 248 ITPELRRYIGERCAKACVDIGYRGAGTFEFLFEN-GEFYFIEMNT 291 +T + + I + + + R +F G+ Y E+NT Sbjct: 256 LTEKHKELIQTYAERVFIHMKLRHLSRIDFFLTQEGQIYLNEVNT 300 >3WO0-A nrPDB Length = 470 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 64/315 (20%), Positives = 106/315 (33%), Gaps = 40/315 (12%) Query: 28 TVAVHSSAD-----RDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGY 82 +VAV D D +H D + + I+ AE+ GA AI Sbjct: 54 SVAVIKDKDYFKSLADFEH---PDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNN 110 Query: 83 GFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDM 142 A+ ER G G + DK A KAGV + + Sbjct: 111 ELFIAP--MAKACERLGLR--GAGVQAAENARDKNKMRDAFNKAGVKSI---KNKRVTTL 163 Query: 143 DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISM------TRAEAKAAFSND 196 + RA + IG P+I+K + G+ ++ + + KA Sbjct: 164 EDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEA 223 Query: 197 MVYMEKYLENPRHVEIQ------------VLADGQGNAIYLAERDCSMQRRHQKVVEEAP 244 E++L+ Q ++ADG+ I + D + Q + P Sbjct: 224 PFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAI--HDKTPQIGFTETSHITP 281 Query: 245 APGITPELRRYIGERCAKACVDIGYRGAGT-FEF-LFENGEFYFIEMNTRIQ--VEHPVT 300 + + E ++ I E KA +G + T E L +N E IE R P Sbjct: 282 S-ILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNMIPNI 340 Query: 301 EMITGVDLIKEQLRI 315 + + G+D+ + L + Sbjct: 341 KKVFGLDMAQLLLDV 355 >5K2M-A nrPDB Length = 273 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 37/204 (18%), Positives = 60/204 (29%), Gaps = 17/204 (8%) Query: 92 AEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKR 151 A E G + GDK+ A + VP + Sbjct: 60 ARLFESEGIPTVNSSRLIFEA-GDKLFATLRLAG-KVPVPEW---KAALSEGGALRVPDS 114 Query: 152 IGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RHV 210 +GYP++ K G GR + V L + + + Y ++++E P R + Sbjct: 115 LGYPLVSKPVFGSWGRLLAKVNDRDSLEAVLE--HRKWMKNPLYGIHYFQEFVEKPGRDI 172 Query: 211 EIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYR 270 V+ AIY H + A P + E KA G Sbjct: 173 RSYVIGGEFVGAIYRYSN-------HW-ITNTARGGKAEPCSDPEVEELSVKAWEAFG-E 223 Query: 271 GAGTFEFLFENGEFYFIEMNTRIQ 294 GA + E+N ++ Sbjct: 224 GALAIDIFESEKGLLVNEVNPNME 247 >1EHI-A nrPDB Length = 377 Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 40/225 (17%), Positives = 76/225 (33%), Gaps = 22/225 (9%) Query: 82 YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGV-PCVPGSDGPLGD 140 +G L E+ + ++G + DK + G+ P Sbjct: 102 HGNLGEDGTLQGLFKLLDKPYVGAPLRGHAVSFDKALTKELLTVNGIRNTKYIVVDPESA 161 Query: 141 DMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYM 200 + I +G V +KA+ G G+ V E +++S + + V + Sbjct: 162 NNWSWDKIVAELGNIVFVKAANQGSSVGISRVTNAEEYTEALSDSFQY------DYKVLI 215 Query: 201 EKYLENPRHVEIQVLAD--------GQGNAIYLAERDCSMQRRHQKVVEEA-----PAPG 247 E+ + R +E+ V+ + G D ++ V A PA Sbjct: 216 EEAVNGARELEVGVIGNDQPLVSEIGAHTVPNQGSGDGWYDYNNKFVDNSAVHFQIPA-Q 274 Query: 248 ITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGE-FYFIEMNT 291 ++PE+ + + + A + RG +FL + Y E NT Sbjct: 275 LSPEVTKEVKQMALDAYKVLNLRGEARMDFLLDENNVPYLGEPNT 319 >3TQT-A nrPDB Length = 372 Score = 69.3 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 35/232 (15%), Positives = 76/232 (32%), Gaps = 18/232 (7%) Query: 71 EITGAVAIHPG-YGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVP 129 A + P +G E+ +E ++G ++ + +K ++ G+P Sbjct: 95 RRYSADCVFPMVHGTQGEDGALQGLLELLNLPYVGANVQSSAVCMEKDLTKTVLRAGGIP 154 Query: 130 CVPGSDGPLGDDMDKN-RAIAKRIGYP-VIIKASGGGGGRGMRVVRGDAELAQSISMTRA 187 V D + + + R G + +KA G V+ + E +++ Sbjct: 155 VVDWHTLSPRDATEGVYQRLLDRWGTSELFVKAVSLGSSVATLPVKTETEFTKAVKEVFR 214 Query: 188 EAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAE---RDCSMQRRHQKV----V 240 +D + +E + R +E VL +G A E + + Sbjct: 215 Y------DDRLMVEPRIRG-REIECAVLGNGAPKASLPGEIIPHHDYYSYDAKYLDPNGA 267 Query: 241 EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 291 + ++ + + I + A + G +F N + E+NT Sbjct: 268 TTTTSVDLSESVTKQIQQIAIDAFKMVHCSGMARVDFFVTPNNKVLVNEINT 319 >2PN1-A nrPDB Length = 331 Score = 68.6 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 53/316 (16%), Positives = 96/316 (30%), Gaps = 32/316 (10%) Query: 3 DKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLN 62 ++I + G A + KE V+ + + +AD+ + P + Sbjct: 5 PHLLITSAGRRAKLVEYFVKEFKTGRVST-ADCSPLASALYMADQHYIV---PKIDEVEY 60 Query: 63 IPAIISAAEITGAVA----IHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVS 118 I +++ + G A I P G L A E+ + G I L DK + Sbjct: 61 IDHLLTLCQDEGVTALLTLIDPELGLL---AQATERFQAIGVTVIVSPYAACELCFDKYT 117 Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAEL 178 + G+ ++ A A + PV +K G +R V E+ Sbjct: 118 MYEYCLRQGI--AHARTYATMASFEEALA-AGEVQLPVFVKPRNGSASIEVRRVETVEEV 174 Query: 179 AQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQK 238 Q S N + +++ L ++ + S+ + + Sbjct: 175 EQLFSK----------NTDLIVQELLVGQE-------LGVDAYVDLISGKVTSIFIKEKL 217 Query: 239 VVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHP 298 + LR + E G G F+ G Y E+N R +P Sbjct: 218 TMRAGETDKSRSVLRDDVFELVEHVLDGSGLVGPLDFDLFDVAGTLYLSEINPRFGGGYP 277 Query: 299 VTEMITGVDLIKEQLR 314 GV+ + R Sbjct: 278 HAYE-CGVNFPAQLYR 292 >3VPB-A nrPDB Length = 282 Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 33/197 (16%), Positives = 69/197 (35%), Gaps = 12/197 (6%) Query: 95 VERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGY 154 +E +G I ++ I + GDK+ + + + G+P D + + ++ G+ Sbjct: 67 LEAAGVHTIN-SSDVINVCGDKILTYSKLYREGIPI---PDSIIALSAEAALKAYEQRGF 122 Query: 155 PVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENP-RHVEIQ 213 P+I K G GR + ++R E I E + +++Y++ R + Sbjct: 123 PLIDKPPIGSWGRLVSLIRDVFEGKTIIE--HRELMGNSALKAHIVQEYIQYKGRDIRCI 180 Query: 214 VLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAG 273 + + A + R + P+ E+ + E KA + Sbjct: 181 AIGEELLGC--YARNIPPNEWRANVALGGTPSNI---EVDEKLKETVVKAVSIVHGEFVS 235 Query: 274 TFEFLFENGEFYFIEMN 290 N + E+N Sbjct: 236 IDILEHPNKGYVVNELN 252 >2R84-A nrPDB Length = 334 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 74/361 (20%), Positives = 126/361 (34%), Gaps = 78/361 (21%) Query: 14 ALRILRACKELGIKTVAVHSSADRDL--KHVLLADETVCIGPAPSVKSYLNIPAIISAAE 71 AL+IL+ K+ G +T+A SS + L K+ +AD I + LN+ A++ Sbjct: 13 ALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVAD--YFIEEKYPEEELLNLNAVV---V 67 Query: 72 ITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCV 131 TG+ H G E VE + G +R D+ +KKAG+ Sbjct: 68 PTGSFVAHLG----------IELVENMKVPYFG-NKRVLRWESDRNLERKWLKKAGIRVP 116 Query: 132 PGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAEL---AQSISMTRAE 188 + P DD++K PVI+K G GG+G + + + A+ + + Sbjct: 117 EVYEDP--DDIEK----------PVIVKPHGAKGGKGYFLAKDPEDFWRKAEKFLGIKRK 164 Query: 189 AKAAFSNDMVYMEKYLEN------------PRHVEIQVLADGQ-GNAIYLAERDCSMQRR 235 + +++Y+ +E+ + N + Q Sbjct: 165 EDL----KNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLE 220 Query: 236 HQKVVEEAPAPGITPELRR-------YIGERCAKACVDI--GYRGAGTFE-FLFENGEFY 285 + I LR GER KA ++ G G E + EF Sbjct: 221 FDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFV 280 Query: 286 FIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHV---RGHAVECRINAE 342 E++ RI + G ++ G P + + + V R A+E R E Sbjct: 281 VFEISARI---------VAGTNI------FVNGSPYTWLRYDRPVSTGRRIAMEIREAIE 325 Query: 343 D 343 + Sbjct: 326 N 326 >4WD3-A nrPDB Length = 413 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 34/181 (18%), Positives = 68/181 (37%), Gaps = 15/181 (8%) Query: 39 LKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERS 98 HV + D+ + S ++ ++ I +E + RS Sbjct: 46 ADHVYIVDDVTDLTVMKS--------LMLEILKVGPIDHIVS----TTEKSILTGGFLRS 93 Query: 99 GFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVII 158 F GP ET M +K++ +K G+P +D ++ A +++G+P+I+ Sbjct: 94 YFGIAGPGFETALYMTNKLAMKTKLKMEGIPV---ADFLCVSQVEDIPAAGEKLGWPIIV 150 Query: 159 KASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG 218 K + G G ++ S + + +N ++ EK +E + ADG Sbjct: 151 KPALGSGALNTFIIHSLDHYEDLYSTSGGLGELKKNNSLMIAEKCIEMEEFHCDTLYADG 210 Query: 219 Q 219 + Sbjct: 211 E 211 >4IWX-A nrPDB Length = 320 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 45/225 (20%), Positives = 79/225 (35%), Gaps = 21/225 (9%) Query: 93 EQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRI 152 Q E G + I DK+ ++ + + G+ DD + Sbjct: 98 RQFEMLGSYPLNESV-AIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVG-- 154 Query: 153 GYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR--HV 210 G P+++K G G G+ + I R N + +++Y++ + + Sbjct: 155 GAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGL------NAHILVQEYIKEAQGCDI 208 Query: 211 EIQVLADGQGNAI-YLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGY 269 V+ D AI A+ H+ A ITP+ R E KA + Sbjct: 209 RCLVVGDEVVAAIERRAKEGDFRSNLHRGGA--ASVASITPQER----EIAIKAARTMAL 262 Query: 270 RGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLR 314 AG + L N +E+N +E E TG+D+ + +R Sbjct: 263 DVAG-VDILRANRGPLVMEVNASPGLEG--IEKTTGIDIAGKMIR 304 >3UFX-B nrPDB Length = 397 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 42/111 (37%), Gaps = 7/111 (6%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGR----GMRVVRG 174 A + + GVP PG + ++ + IA+ G V+IKA GGR G+++ Sbjct: 8 AKEILARYGVPVPPG---KVAYTPEEAKRIAEEFGKRVVIKAQVHVGGRGKAGGVKLADT 64 Query: 175 DAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYL 225 E + + V + + ++ + ++ D + L Sbjct: 65 PQEAYEKAQAILGMNIKGLTVKKVLVAEAVDIAKEYYAGLILDRAKKRVVL 115 >3WVR-A nrPDB Length = 447 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 41/193 (21%), Positives = 65/193 (33%), Gaps = 26/193 (13%) Query: 134 SDGPLGDDMDKNRAIAKRI---GYPVIIKASGGGGG--------------RGMRVVR--G 174 G + D + R+ G PVI+K G G RG R +R Sbjct: 157 PAGAVCADRRRAHRHVTRLLDEGSPVILKQDYGSGSDGNEILSRTPGLALRGARALRVLA 216 Query: 175 DAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQR 234 D+ + R + V +E+Y R + G + L M+ Sbjct: 217 DSAALDAYLDERWDWLTEGGRHRVVVERYHPGSRAYFAEFWISDGG--VRLGGHG-EMRY 273 Query: 235 RHQKVVEEAPAPGITPELRRYIGERCAKACV---DIGYRGAGTFEFLFE-NGEFYFIEMN 290 R + PAP + + E + CV +GYRG + + + GE F E N Sbjct: 274 RPLPDSQVMPAPDLDQAQLDDLVEGGRRLCVALHALGYRGVLSADAVVTPAGEVLFTEHN 333 Query: 291 TRIQVEHPVTEMI 303 R + E++ Sbjct: 334 GRATGSTHIYEIV 346 >2NU8-B nrPDB Length = 388 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 51/139 (36%), Gaps = 18/139 (12%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGY-PVIIKASGGGGGR----GMRVVR 173 A + G+P G + ++ A +IG P ++K GGR G++VV Sbjct: 8 AKQLFARYGLPAPVGYACTTPREAEEA---ASKIGAGPWVVKCQVHAGGRGKAGGVKVVN 64 Query: 174 GDAELAQSIS-------MTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG-QGNAIYL 225 ++ +T + + +E + + + + + D +++ Sbjct: 65 SKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFM 124 Query: 226 AERDCSMQRRHQKVVEEAP 244 A + ++ KV EE P Sbjct: 125 ASTEGGVEIE--KVAEETP 141 >1WR2-A nrPDB Length = 238 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIK 159 A +K G+P + L +D+ AK IGYPV++K Sbjct: 25 AKQVLKAYGLPV---PEEKLAKTLDEALEYAKEIGYPVVLK 62 >4XZ3-B nrPDB Length = 230 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 32/200 (16%), Positives = 70/200 (35%), Gaps = 22/200 (11%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIK-----ASGGGGGRGMRV-V 172 A + G+P ++ L ++ ++ IG+PV++K G++V + Sbjct: 23 AKYFISSYGIPV---TNIRLAKSEEEAVNFSREIGFPVVLKIVSPQVVHKSDVGGVKVNL 79 Query: 173 RGDAELAQSISMTRAEAKAAFSNDM---VYMEKYLENPRHVEIQVLAD-GQGNAIYLAER 228 R + E+ ++ K N + ++++ + I +L D G + Sbjct: 80 RSEEEVRKAYREIIENVKRNVPNAEIEGILVQEFAPPGVELIIGLLRDPQFGPTVMFGLG 139 Query: 229 DCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIE 288 ++ AP ++ + + + + G+RG + Sbjct: 140 GVFVELFRDVSFRVAP---LSEQDAESMIKEVKAYKLLTGFRGMEPVDIEAIKDALI--- 193 Query: 289 MNTRIQVEHPVTEMITGVDL 308 RI VE+ E I +DL Sbjct: 194 RAGRIGVEN---EEIAEMDL 210 >4FFM-A nrPDB Length = 363 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 53/298 (17%), Positives = 91/298 (30%), Gaps = 55/298 (18%) Query: 22 KELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPG 81 K+ G+K V V + ADE C ++ ++ A+ P Sbjct: 21 KKAGMKVVLV--DKNPQALIRNYADEFYCF------DVIKEPEKLLELSKR--VDAVLP- 69 Query: 82 YGFLSENANFAEQVERSGFIFIGP---KAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPL 138 ++EN E + F P E R+ DK + K GVP Sbjct: 70 ---VNENLACIEFLNSIKEKFSCPVLFDFEAYRISRDKKKSKDYFKSIGVPTPQDRPSKP 126 Query: 139 GDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMV 198 P +K G R++ D +L + Sbjct: 127 ----------------PYFVKPPCESSSVGARIIYDDKDLE--------------GLEPD 156 Query: 199 YMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGE 258 + + V ++V+ DG A+ + +V PA P R+ + Sbjct: 157 TLVEEYVEGEVVSLEVVGDGSHFAVVKETLVHIDETYDCHMVTPLPA---NPLFRQISHD 213 Query: 259 RCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHP-VTEMITGVDLIKEQLRI 315 A + +G E +F IE++ R + P V +G++LI+ R Sbjct: 214 LAAN----LPLKGIMDVEAIFGPKGLRVIEIDARFPSQTPTVVYYSSGINLIELLFRA 267 >6G4Q-B nrPDB Length = 415 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 41/224 (18%), Positives = 72/224 (32%), Gaps = 40/224 (17%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYP-VIIKASGGGGGR---------- 167 ++ +++AGV G + D+ AIAK++G V+IKA GGR Sbjct: 10 SMELLQEAGVSVPKGY---VAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK 66 Query: 168 -GMRVVRGDAELAQSISMTRAEAKAAFSNDM--------VYME-KYLENPRHVEIQVLAD 217 G+++V E S + + E KY + I + Sbjct: 67 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS 126 Query: 218 GQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIG---ERCAKACVDIGY----- 269 QG + + V E+P I + G E+ + +G+ Sbjct: 127 FQGPVLIGSSHGGVNIED---VAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIV 183 Query: 270 ----RGAGTFEFLFENGEFYFIEMNTRI-QVEHPVTEMITGVDL 308 LF + IE+N + + V M ++ Sbjct: 184 ESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINF 227 >3DF7-A nrPDB Length = 305 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 30/196 (15%), Positives = 65/196 (33%), Gaps = 49/196 (25%) Query: 103 IGPKAETIRLMGDKVS-AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKAS 161 +G + I + DK + VP + + + IIK Sbjct: 98 LGSSSRAIAVTSDKWELYKKLRGEVQVP----------------QTSLRPLDCKFIIKPR 141 Query: 162 GGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGN 221 G G+ S + A ++++E ++ + + Sbjct: 142 TACAGEGI-----------GFSDEVPDGHIA--------QEFIEG-INLSVSLAVGEDVK 181 Query: 222 AIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDI----GYRGAGTFEF 277 + + E+ + + PA I+ E++R + E +A + GY G + Sbjct: 182 CLSVNEQ---IINNFRYAGAVVPAR-ISDEVKREVVEEAVRAVECVEGLNGYVG---VDI 234 Query: 278 LFENGEFYFIEMNTRI 293 ++ + + Y IE+N R+ Sbjct: 235 VYSD-QPYVIEINARL 249 >5I47-A nrPDB Length = 277 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 60/177 (33%), Gaps = 13/177 (7%) Query: 86 SENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKN 145 +E A A + G + +A T RL+ D+++ + + A +P + + + Sbjct: 63 AERAVLAALLASGGTPVVN-RAATARLLADRMALLRHLILADIPV---PETRVCFGEEAI 118 Query: 146 RAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLE 205 A IGYPV++K+ G + +V + V +++++ Sbjct: 119 FAAIAEIGYPVVLKSLTVDPGFPVALVEDQDAAEA---IVEHRIMLG-GERAVLVQQFIP 174 Query: 206 NPRHVEI-QVLADGQGNAI----YLAERDCSMQRRHQKVVEEAPAPGITPELRRYIG 257 + V+A I + R + AP + + +G Sbjct: 175 ARAGQSVRLVVAGRSLAGIEQRTHGGWRPGRDATYEAYTGDPAPLTALAERIIERLG 231 >5UA0-A nrPDB Length = 329 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 54/153 (35%), Gaps = 10/153 (6%) Query: 63 IPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAA 122 A+I AA+ G + +G + E E + + GP +KV + Sbjct: 67 GKAVIKAADSAGVNIVPTSFGSVEEAGQTVEVCGKE-ILVHGPTER------EKVLSSVF 119 Query: 123 MKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSI 182 K P + D + ++ N + ++G P ++ +GG R + V A Sbjct: 120 EK---YPELIVVDYTIPSAVNDNAELYGKVGVPFVMGTTGGDRTRLYKTVEESKIYAVIS 176 Query: 183 SMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVL 215 + A + + E++ ++V+ Sbjct: 177 PQMGKQVVAFLAAMEIMSEQFPGAFAGYSLEVM 209 >2A9V-A nrPDB Length = 212 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 2/62 (3%) Query: 1 MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSY 60 ML V+ N G+ R R +ELG+ T V + D L D V G AP++ Sbjct: 13 MLKIYVVDNGGQWTHREWRVLRELGVDTKIVPNDIDSSELDGL--DGLVLSGGAPNIDEE 70 Query: 61 LN 62 L+ Sbjct: 71 LD 72 >6MEL-B nrPDB Length = 387 Score = 32.7 bits (73), Expect = 0.32, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 70/196 (35%), Gaps = 26/196 (13%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPV-----IIKASGGGGGRGMRVVR 173 A A G+P + G + +D+ A AK +G V I A G G G G+++ + Sbjct: 8 AKAIFVDNGIPTL---KGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAK 64 Query: 174 GDAELAQSIS-------MTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYL- 225 E+ S +T +Y+E + + +L + I + Sbjct: 65 NLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITII 124 Query: 226 --AERDCSMQRRHQKVVEEAPAPGITPELRRYI-----GERCAKACVDIGYR---GAGTF 275 +E +++ ++ E+ GI P++ + R D G + Sbjct: 125 ASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISMIAKL 184 Query: 276 EFLFENGEFYFIEMNT 291 L+ + + +E+N Sbjct: 185 YKLYMDKDMNMLEINP 200 >3JZG-A nrPDB Length = 402 Score = 32.0 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 54/125 (43%), Gaps = 19/125 (15%) Query: 332 GHAV-ECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPY--------YD 382 G+A+ E + + DPN L +++ HA + ++ ++ + V + YD Sbjct: 151 GNAINELKFHPRDPNLLL----SVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYD 206 Query: 383 SMIGKLICYGEN-----RDVAIARMKNALQE-LIIDGIKTNVDLQIRIMNDENFQHGGTN 436 + K++ G + + RM NA++E + KTN + ++ +F + Sbjct: 207 LLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIH 266 Query: 437 IHYLE 441 +Y++ Sbjct: 267 RNYVD 271 >4P4R-B nrPDB Length = 212 Score = 31.6 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 25/80 (31%), Gaps = 1/80 (1%) Query: 164 GGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYL-ENPRHVEIQVLADGQGNA 222 GGG + G ++ + AF+ ++E+Y+ V Sbjct: 12 GGGSLVPRGSGGGGSPENYLFQGRQECYAFNGTQRFLERYIYNREEFVRFDSDVGEFRAV 71 Query: 223 IYLAERDCSMQRRHQKVVEE 242 L D + ++EE Sbjct: 72 TELGRPDEEYWNSQKDILEE 91 >1CER-O nrPDB Length = 331 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 42/121 (34%), Gaps = 4/121 (3%) Query: 102 FIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKAS 161 ++ + IR K +AGV V S G + D DK +A + VII A Sbjct: 61 YLYVDGKAIRATAVKDPKEIPWAEAGVGVVIESTG-VFTDADKAKAHLEGGAKKVIITAP 119 Query: 162 GGGGGRGMRVVRGDA-ELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQG 220 G + +V G E + +N + + K LE VE ++ Sbjct: 120 --AKGEDITIVMGVNHEAYDPSRHHIISNASCTTNSLAPVMKVLEEAFGVEKALMTTVHS 177 Query: 221 N 221 Sbjct: 178 Y 178 >1PK8-A nrPDB Length = 422 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 26/163 (15%), Positives = 46/163 (28%), Gaps = 34/163 (20%) Query: 57 VKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDK 116 Y ++ + A I ++H Y F + FA+ V Sbjct: 196 NGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLH------------------ 237 Query: 117 VSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDA 176 KK G P D ++ + YPV++K G G V Sbjct: 238 -------KKLGTEEFPLID---QTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQH 287 Query: 177 ELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQ 219 + S+ A + E +++ V +Q + Sbjct: 288 DFQDIASVVALTKTYATA------EPFIDAKYDVRVQKIGQNY 324 >2PZ0-A nrPDB Length = 252 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 70/196 (35%), Gaps = 34/196 (17%) Query: 258 ERCAKACVDIGYRGAGTFEFLFE-NGEFYFIE--MNTRIQVEHPVTEMITGVDLIKEQLR 314 E + G+ T E + + + F E RI + V E+I D + + Sbjct: 61 ETVDRTTNGEGFVKDFTLEEIKKLDAGIKFGEKFAGERIPTLYEVFELIGDKDFLVN-IE 119 Query: 315 IAAGQPLSIKQEEV---HVRGHAVECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHI 371 I +G L EE ++ + E R+ N + S + + G+ ++ + Sbjct: 120 IKSGIVLYPGIEEKLIKAIKEYNFEERVIISSFNHY--SLRDVKKMAPHLKIGLLYQCGL 177 Query: 372 ---------YAGYTVPPYYDSMI-----------GKLICYGENRDVAIARMKNALQELII 411 Y++ P+Y ++I KL + +R + RM A + Sbjct: 178 VEPWHMALRMEAYSLHPFYFNIIPELVEGCKKNGVKLFPWTVDRKEDMERMIKA----GV 233 Query: 412 DGIKTNVD-LQIRIMN 426 DGI T+ I ++ Sbjct: 234 DGIITDDPETLINLVR 249 >1N9W-A nrPDB Length = 422 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 62/178 (34%), Gaps = 39/178 (21%) Query: 87 ENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNR 146 E A AE +E E + GD++ + A P P D P + R Sbjct: 234 EEALLAEMLE-----------EALNTAGDEIR----LLGATWPSFPQ-DIPRLTHAEAKR 277 Query: 147 AIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLEN 206 + + +GYPV G ++ + AK + +D +++ +Y + Sbjct: 278 ILKEELGYPV-----------------GQDLSEEAERLLGEYAKERWGSDWLFVTRYPRS 320 Query: 207 PRHVEIQVLADGQGNAIYLAERDCSM----QRRHQK--VVEEAPAPGITPELRRYIGE 258 R DG + L R + QR H+ ++E A G+ PE E Sbjct: 321 VRPFYTYPEEDGTTRSFDLLFRGLEITSGGQRIHRYEELLESLKAKGMDPEAFHGYLE 378 >6MGG-B nrPDB Length = 387 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 30/82 (36%), Gaps = 6/82 (7%) Query: 119 AIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGR----GMRVVRG 174 A ++ G+ G + + +A + G ++KA GGR G++VV+ Sbjct: 8 AKDLLESYGLKVQKGI--VAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKS 65 Query: 175 DAELAQSISMTRAEAKAAFSND 196 E + + F D Sbjct: 66 SQETREVAESLIGKNLVTFQTD 87 >4QL6-A nrPDB Length = 634 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 30/219 (13%), Positives = 61/219 (27%), Gaps = 27/219 (12%) Query: 63 IPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAA 122 + ++ E TG GFLS+ + +G + + + + I+ Sbjct: 374 LGLVLDIRENTG--------GFLSQAIKVSGLFLTNGVVVV---SRYADGSVKRYRTISP 422 Query: 123 MKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRG--MRVVRGDAELAQ 180 K P + + G +I+ G+G + + Sbjct: 423 QKFYDGPLAVLVSKSSAAAAEIVAQTLQDYGVALIV-GDQQTYGKGTIQHQTITGSNSQE 481 Query: 181 SI----------SMTRAEAKAAFSNDMVYMEKYLE---NPRHVEIQVLADGQGNAIYLAE 227 ++ +D+V +Y E R +E + AD N I Sbjct: 482 DFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDKLGERFLEYALPADQYDNVINDNL 541 Query: 228 RDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVD 266 D + R +P + R + + A + Sbjct: 542 GDLDINIRPWFQKYYSPHLQKPELVWREMLPQLAHNSQE 580 >3S99-A nrPDB Length = 356 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 2/78 (2%) Query: 88 NANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAG--VPCVPGSDGPLGDDMDKN 145 + AE+ + GFI+IGP + + ++ G V + G D +++ Sbjct: 19 PGSMAEEKLKVGFIYIGPPGDFGWTYQHDQARKELVEALGDKVETTFLENVAEGADAERS 78 Query: 146 RAIAKRIGYPVIIKASGG 163 R G +I S G Sbjct: 79 IKRIARAGNKLIFTTSFG 96 >4KP2-A nrPDB Length = 441 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 23/56 (41%) Query: 256 IGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKE 311 + + C +IG RGA + ++M+ R+ + + EM +I+ Sbjct: 189 AKDIVLRVCKEIGRRGATYMAIEYGGEVVKNMDMDGRLTLCNMAIEMGGKTGVIEA 244 >5DZS-A nrPDB Length = 276 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 6/54 (11%) Query: 397 VAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQH------GGTNIHYLEKKL 444 I+++ A++ L I G+ V + RIM +F G N L + + Sbjct: 41 EDISKLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENM 94 >5NQA-A nrPDB Length = 578 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 37/97 (38%), Gaps = 7/97 (7%) Query: 161 SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQG 220 + G G+ ++ + EL Q + A + +D + + +++E+ R E + Sbjct: 73 ALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYR 132 Query: 221 N-------AIYLAERDCSMQRRHQKVVEEAPAPGITP 250 + E ++ R V+E +PA + Sbjct: 133 TLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKE 169 >5HAA-A nrPDB Length = 470 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 23/158 (14%), Positives = 44/158 (27%), Gaps = 10/158 (6%) Query: 136 GPLGDDMDKNRAIAKRIG----YPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKA 191 D+D G PV+ G G R+ G+ + Sbjct: 317 YGSRRDIDNALKKIMEAGKDKYLPVMTGHQGEPGAVLGRIANGETPFKVETGDRIIFSAN 376 Query: 192 AFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVE-EAPAPGITP 250 N M +Y ++++ + +++ + + H +++ P I Sbjct: 377 VIPNPMTQANRYAL---ETKLKMKGARIYDNVHV--SGHAYREDHWELLRMLKPEHVIPA 431 Query: 251 ELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIE 288 + + D GY T L E Y E Sbjct: 432 HGTIQMHSEYIQMAEDAGYSLGDTLHLLRNGEELYIEE 469 >2YYI-A nrPDB Length = 481 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 67/217 (30%), Gaps = 34/217 (15%) Query: 44 LADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFI 103 +A + V + A +++L + A++ AE GA YG + E AE +++ Sbjct: 284 MAHQVVALKTAK-TEAFLGVAALM--AEGIGADV----YGHVQE--KIAEI-----IVYL 329 Query: 104 GPKAETIRLMGDKVS--AIAAMKKAGVPCVPGSDGPL---GDDMDKNRAIAKRIGYPVII 158 E +R + A VP DG + R I ++IG +I Sbjct: 330 ----EAMRAFWTRAEEEAKENAYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLI 385 Query: 159 KASGGGGGRG----------MRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPR 208 +G E + + F E++ Sbjct: 386 TLPSEKDFKGPLGPFLEKFLQGAALEAKERVALFRLAWDMTLSGFGARQELYERFFFGDP 445 Query: 209 HVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPA 245 Q L + Y ER + + KV EE A Sbjct: 446 VRMYQTLYNVYNKEPY-KERIRAFLKESLKVFEEVQA 481 >4ROQ-A nrPDB Length = 324 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 22/43 (51%) Query: 121 AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGG 163 + K GVP + L +++ + K+IG+ V+I+ + G Sbjct: 102 ILIPKVGVPADVYAIDVLTTQIEQAKKREKKIGFEVLIETALG 144 >3NYS-A nrPDB Length = 367 Score = 28.5 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 21/69 (30%), Gaps = 2/69 (2%) Query: 130 CVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA--SGGGGGRGMRVVRGDAELAQSISMTRA 187 +P S D D AIA + G PVI A S G +G R S + Sbjct: 127 IIPVSLYGQCADFDAINAIASKYGIPVIEDAAQSFGASYKGKRSCNLSTVACTSFFPSAP 186 Query: 188 EAKAAFSND 196 Sbjct: 187 LGCYGDGGA 195 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.133 0.338 Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,459,271 Number of Sequences: 36641 Number of extensions: 644597 Number of successful extensions: 2427 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 97 Number of HSP's successfully gapped in prelim test: 60 Number of HSP's that attempted gapping in prelim test: 2089 Number of HSP's gapped (non-prelim): 168 length of query: 449 length of database: 10,336,785 effective HSP length: 100 effective length of query: 349 effective length of database: 6,672,685 effective search space: 2328767065 effective search space used: 2328767065 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.1 bits)