BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P24158 (256 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FUJ-A nrPDB 458 e-130 1PPF-E nrPDB 239 1e-63 1AE5-A nrPDB 184 2e-47 1EUF-A nrPDB 170 4e-43 1FI8-A nrPDB 162 1e-40 2RDL-A nrPDB 159 1e-39 1NN6-A nrPDB 155 2e-38 1IAU-A nrPDB 150 5e-37 1UTJ-A nrPDB 150 6e-37 3RP2-A nrPDB 149 2e-36 1KYN-A nrPDB 144 3e-35 1F7Z-A nrPDB 143 7e-35 3TK9-A nrPDB 143 8e-35 3G01-A nrPDB 143 9e-35 4AN7-A nrPDB 142 2e-34 1A0J-A nrPDB 141 3e-34 1FDP-A nrPDB 139 1e-33 5C67-A nrPDB 135 2e-32 4Q7Y-A nrPDB 134 3e-32 2EEK-A nrPDB 133 7e-32 1AZZ-A nrPDB 130 4e-31 4WWY-A nrPDB 129 9e-31 2ZKS-A nrPDB 129 1e-30 5FXL-A nrPDB 129 2e-30 3QUM-P nrPDB 127 6e-30 1MZD-A nrPDB 125 1e-29 4NFE-A nrPDB 124 3e-29 2TLD-E nrPDB 124 4e-29 5UGG-A nrPDB 124 6e-29 5FCR-A nrPDB 123 6e-29 1BRU-P nrPDB 123 9e-29 1ORF-A nrPDB 122 1e-28 1GVZ-A nrPDB 122 2e-28 4DUR-A nrPDB 121 2e-28 4H4F-A nrPDB 120 6e-28 1ELT-A nrPDB 119 1e-27 5MS3-A nrPDB 119 2e-27 1PYT-D nrPDB 118 3e-27 1SPJ-A nrPDB 117 5e-27 5LHN-A nrPDB 116 1e-26 1NPM-A nrPDB 116 1e-26 1TON-A nrPDB 114 4e-26 1SGF-G nrPDB 113 7e-26 2CGA-A nrPDB 112 1e-25 2V35-A nrPDB 112 2e-25 1FIZ-A nrPDB 112 2e-25 5TJX-A nrPDB 111 3e-25 3S9B-A nrPDB 110 5e-25 1LTO-A nrPDB 109 1e-24 5ZFH-A nrPDB 109 1e-24 3W94-A nrPDB 109 1e-24 4MPW-A nrPDB 107 6e-24 1AO5-A nrPDB 104 3e-23 6I44-A nrPDB 104 4e-23 1FON-A nrPDB 104 4e-23 2BDH-A nrPDB 103 5e-23 1FXY-A nrPDB 103 5e-23 5XRF-A nrPDB 103 5e-23 1SGF-A nrPDB 103 7e-23 5GVT-A nrPDB 103 9e-23 1FIW-A nrPDB 102 1e-22 1SC8-U nrPDB 102 1e-22 5XW8-A nrPDB 102 1e-22 1P57-B nrPDB 102 2e-22 2PSX-A nrPDB 102 2e-22 3T2N-A nrPDB 102 2e-22 1EQ9-A nrPDB 100 5e-22 6QHB-A nrPDB 100 1e-21 3F6U-H nrPDB 99 1e-21 2AIQ-A nrPDB 99 2e-21 4GSO-A nrPDB 99 3e-21 3BSQ-A nrPDB 98 3e-21 1YM0-A nrPDB 98 4e-21 1BDA-A nrPDB 97 7e-21 1YC0-A nrPDB 96 1e-20 4E7N-A nrPDB 96 1e-20 2R0L-A nrPDB 96 1e-20 2F91-A nrPDB 96 2e-20 1X7A-C nrPDB 95 2e-20 3LC3-A nrPDB 95 3e-20 1SI5-H nrPDB 94 5e-20 2ASU-B nrPDB 94 7e-20 3DFJ-A nrPDB 94 8e-20 4DGJ-A nrPDB 92 2e-19 3E0N-B nrPDB 92 2e-19 1EKB-B nrPDB 91 4e-19 3VGC-B nrPDB 90 8e-19 1OP0-A nrPDB 90 8e-19 2JET-B nrPDB 89 1e-18 2F83-A nrPDB 89 2e-18 1A5I-A nrPDB 89 2e-18 4XDE-A nrPDB 88 3e-18 1M9U-A nrPDB 88 4e-18 6AOD-C nrPDB 86 1e-17 2XXL-A nrPDB 85 3e-17 1BQY-A nrPDB 84 4e-17 3P8G-A nrPDB 84 6e-17 3S69-A nrPDB 84 7e-17 4LK4-A nrPDB 82 2e-16 2OLG-A nrPDB 80 1e-15 3H7O-A nrPDB 80 1e-15 2B9L-A nrPDB 79 1e-15 2PKA-B nrPDB 79 1e-15 1C5M-D nrPDB 79 1e-15 5KWM-A nrPDB 79 2e-15 5LPF-A nrPDB 79 3e-15 2OQ5-A nrPDB 78 4e-15 4Z6A-H nrPDB 77 7e-15 4IGD-A nrPDB 76 1e-14 1KIG-H nrPDB 75 3e-14 4DJZ-B nrPDB 74 5e-14 4IW4-E nrPDB 74 6e-14 2XRC-A nrPDB 73 1e-13 5O32-I nrPDB 73 1e-13 4KKD-A nrPDB 70 7e-13 1PQ7-A nrPDB 66 1e-11 4BXW-A nrPDB 66 2e-11 5UBM-A nrPDB 63 1e-10 2HLC-A nrPDB 63 1e-10 6BQM-A nrPDB 63 1e-10 1ELV-A nrPDB 63 2e-10 1EPT-B nrPDB 62 2e-10 4J1Y-A nrPDB 62 3e-10 1VR1-H nrPDB 61 6e-10 3H7T-A nrPDB 60 7e-10 3NXP-A nrPDB 59 2e-09 3I77-A nrPDB 59 2e-09 4NZQ-A nrPDB 59 2e-09 3K65-B nrPDB 59 3e-09 1MKW-K nrPDB 58 4e-09 1ETT-H nrPDB 58 4e-09 2OCV-B nrPDB 57 8e-09 5TO3-B nrPDB 57 1e-08 1AKS-B nrPDB 55 2e-08 2QY0-B nrPDB 55 3e-08 1GPZ-A nrPDB 54 6e-08 3BEU-A nrPDB 53 1e-07 1MD7-A nrPDB 53 1e-07 2KAI-A nrPDB 53 1e-07 1RIW-B nrPDB 52 3e-07 1BBR-H nrPDB 51 4e-07 2FMJ-A nrPDB 51 6e-07 3F1S-B nrPDB 47 1e-05 3H5C-B nrPDB 47 1e-05 1ZJK-A nrPDB 46 2e-05 1Q3X-A nrPDB 45 2e-05 4FXG-H nrPDB 43 2e-04 1DLE-A nrPDB 39 0.002 2OK5-A nrPDB 39 0.002 2WIN-I nrPDB 39 0.002 3RU4-E nrPDB 39 0.003 2JET-C nrPDB 38 0.005 2HNT-C nrPDB 37 0.007 2I6S-A nrPDB 32 0.24 1P3E-A nrPDB 31 0.60 1ZCB-A nrPDB 30 0.72 3AHE-A nrPDB 29 2.5 2B0O-E nrPDB 28 3.3 2WIY-A nrPDB 28 4.5 3LVQ-E nrPDB 28 4.8 5LAK-A nrPDB 27 5.8 5XIG-A nrPDB 27 7.3 2GRV-A nrPDB 27 7.3 5ZT8-A nrPDB 27 9.7 >1FUJ-A nrPDB Length = 221 Score = 458 bits (1179), Expect = e-130, Method: Compositional matrix adjust. Identities = 220/221 (99%), Positives = 221/221 (100%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 HNVRTQEPTQQHFSVAQVFLNNYDAENKLND+LLIQLSSPANLSASVATVQLPQQDQPVP Sbjct: 61 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVP 120 Query: 148 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 207 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL Sbjct: 121 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 180 Query: 208 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR Sbjct: 181 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1PPF-E nrPDB Length = 218 Score = 239 bits (609), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 120/221 (54%), Positives = 161/221 (72%), Gaps = 3/221 (1%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A+PH+ P+M SLQ+RG HFCG TLI P+FV++AAHC+ ++ R V VVLGA Sbjct: 1 IVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 HN+ +EPT+Q F+V ++F N YD N LND++++QL+ A ++A+V QLP Q + + Sbjct: 58 HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 117 Query: 148 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 207 +G QCLAMGWG +G + A VLQELNVTVVT CR N+CT V R+AG+CFGDSG PL Sbjct: 118 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPL 177 Query: 208 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 +C+G+I GI SFV GCA+ L+PD F VA +V+WI S ++ Sbjct: 178 VCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1AE5-A nrPDB Length = 225 Score = 184 bits (468), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 99/222 (44%), Positives = 139/222 (62%), Gaps = 7/222 (3%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG +A+P P++AS+Q N G HFCGG LIH FV+TAA C + + VVLGA Sbjct: 1 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 88 HNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 +++R +E ++Q FS++ + N YD + LND++L+QL ANL++SV + LP Q+ V Sbjct: 58 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 117 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHNICTFVPRRKAGICFGDSGG 205 GT+C GWG + ++ + +NVTV CRP+N+CT V R+ GIC GD G Sbjct: 118 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGT 177 Query: 206 PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 PL+C+G+ G+ SF + C PDFFTRVAL+ DWI L Sbjct: 178 PLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 217 >1EUF-A nrPDB Length = 227 Score = 170 bits (431), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 94/234 (40%), Positives = 136/234 (58%), Gaps = 17/234 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA L + + SH CGG L+ FVLTAAHCL +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCL----GSSINVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ +E TQQ V + + +Y+ E ND++L++L+ A+++ V+ + LP+ V Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---FFCRPHN------ICTFVPRRKAG 197 G C GWGR+G + P LQE+++ V + R N IC P ++ Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKN 176 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVE 251 GDSGGPL+C+G+ QGI V +G PD +TR++ ++ WI ST+RR + Sbjct: 177 SFSGDSGGPLVCNGVAQGI---VSYGRNDGTTPDVYTRISSFLSWIHSTMRRYK 227 >1FI8-A nrPDB Length = 228 Score = 162 bits (411), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 90/234 (38%), Positives = 131/234 (55%), Gaps = 19/234 (8%) Query: 28 IVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GGHEA+PHSRPYMA LQ M GS CGG LI FVLTAAHC + V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKIQVTLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AHN++ QE QQ V ++ + Y+++ ND++L++L S A S++V + LP+++ Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV----------VTFFCRPHNICTFVPRRK 195 V G C GWG++G + LQE+ +TV +F + + IC P+ K Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GDSGGPL+C + GI V +G P FT+V+ ++ WI+ T+++ Sbjct: 177 RASFRGDSGGPLVCKKVAAGI---VSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 227 >2RDL-A nrPDB Length = 226 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 89/233 (38%), Positives = 130/233 (55%), Gaps = 19/233 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHF--CGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 I+GG E +PH+RPYMA L++ P +H C G LI +FV+TAAHC R + V+L Sbjct: 1 IIGGTECRPHARPYMAYLEIV-TPENHLSACSGFLIRRNFVMTAAHCA----GRSITVLL 55 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 GAHN + +E T Q V + F + YD LND++L++L ANL+ V T+ + + Sbjct: 56 GAHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSN 115 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV--------TFFCRPHNICTFVPRRKA 196 +P G C A+GWGR ++PP+ LQE+ + ++ F + +C P++ Sbjct: 116 SIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIR 175 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 + GDSGGPL+C GI QGI S+V+ P FTR++ Y WI LR Sbjct: 176 NVYKGDSGGPLLCAGIAQGIASYVLRNAKP---PSVFTRISHYRPWINKILRE 225 >1NN6-A nrPDB Length = 228 Score = 155 bits (392), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 93/233 (39%), Positives = 128/233 (54%), Gaps = 17/233 (7%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVV 84 EI+GG E +PHSRPYMA L++ + G S FCGG LI +FVLTAAHC R + V Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVT 56 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 LGAHN+ +E T Q V + F + Y+ +D++L++L A+L+ +V T+ P Q Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT------FFCRPHN--ICTFVPRRK 195 VP G C GWGR G P + LQE+ + ++ F HN +C PR+ Sbjct: 117 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKT 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 GDSGGPL+C G+ QGI V +G + P FTR++ Y WI L+ Sbjct: 177 KSAFKGDSGGPLLCAGVAQGI---VSYGRSDAKPPAVFTRISHYRPWINQILQ 226 >1IAU-A nrPDB Length = 227 Score = 150 bits (379), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 88/233 (37%), Positives = 123/233 (52%), Gaps = 18/233 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA L + CGG LI FVLTAAHC +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ QEPTQQ V + + Y+ +N ND++L+QL A + +V ++LP V Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRKA 196 G C GWG+ + LQE+ +TV ++ +C P K Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GDSGGPL+C+ + QGI S+ G + P T+V+ +V WI+ T++R Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSY---GRNNGMPPRACTKVSSFVHWIKKTMKR 226 >1UTJ-A nrPDB Length = 242 Score = 150 bits (378), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 90/247 (36%), Positives = 137/247 (55%), Gaps = 24/247 (9%) Query: 14 LLALLLSGAARAAE---IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAA 70 L+ +LL GAA A E IVGG+E +P+S+P+ SL N G HFCGG+L++ ++V++AA Sbjct: 4 LVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVVSAA 59 Query: 71 HCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPAN 129 HC + V V LG HN++ E ++Q S ++V + NY + N ND++LI+LS PA Sbjct: 60 HCYK----SRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPAT 115 Query: 130 LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF--------- 180 L+ V V LP P GT C GWG + + LQ LN+ ++++ Sbjct: 116 LNTYVQPVALPTSCAPA--GTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG 173 Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 C C GDSGGP++C+G +QG+ S+ +GCA P + +V ++ Sbjct: 174 MITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFN 232 Query: 241 DWIRSTL 247 DW+ ST+ Sbjct: 233 DWLTSTM 239 >3RP2-A nrPDB Length = 224 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 86/230 (37%), Positives = 121/230 (52%), Gaps = 17/230 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSH-FCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG E+ PHSRPYMA L + G CGG LI FVLTAAHC R + V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 87 AHNVRTQEPTQQHFSV-AQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH+VR +E TQQ V Q+ +Y++ L+D++L++L L+ +V V LP Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FFCRPHNICTFVPRRKAG 197 + G C A GWG+ G DP + L+E+ + ++ ++ +C P Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 GDSGGPL+C G+ GI S+ G P FTRV+ YV WI + + Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSY---GHPDAKPPAIFTRVSTYVPWINAVI 223 >1KYN-A nrPDB Length = 235 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 86/231 (37%), Positives = 126/231 (54%), Gaps = 18/231 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E++PHSRPYMA LQ++ G CGG L+ FVLTAAHC +NV LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN----INVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ +E TQQH + + + Y+ ND++L+QLS + +V V LP+ + + Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTV---------VTFFCRPHNICTFVPRRKAG 197 GT C GWGRV L+E+ + V + IC R + Sbjct: 117 RPGTLCTVAGWGRVSMRR-GTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKA 175 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 GDSGGPL+C+ + GI S+ G ++ + P+ FTRV+ ++ WIR+T+R Sbjct: 176 AFKGDSGGPLLCNNVAHGIVSY---GKSSGVPPEVFTRVSSFLPWIRTTMR 223 >1F7Z-A nrPDB Length = 233 Score = 143 bits (361), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 91/233 (39%), Positives = 130/233 (55%), Gaps = 26/233 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ Q +S PY SL N G HFCGG+LI+ +V++AAHC + + V LG Sbjct: 11 IVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCYK----SRIQVRLGE 62 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E +Q + A++ + N+D + ND++LI+LSSP L+A VATV LP Sbjct: 63 HNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPS--SCA 120 Query: 147 PHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVV-TFFCR--------PHNICTFVPRR 194 P GTQCL GWG G ++P +LQ L+ ++ C + +C Sbjct: 121 PAGTQCLISGWGNTLSSGVNEP--DLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QGI S+ +GCA P +T+V YVDWI+ T+ Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTI 230 >3TK9-A nrPDB Length = 226 Score = 143 bits (360), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 123/234 (52%), Gaps = 19/234 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA +Q CGG L+ FVLTAAHC +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSS----INVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ QE TQQ V + + Y+ +N N+++L+QL A + +V ++LP V Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRKA 196 G C GWG V + A LQE+ +TV + R IC P++ Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 GDSGGPL+C + QGI S+ G P + +V+ ++ WI+ T++R+ Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSY---GNKKGTPPGVYIKVSHFLPWIKRTMKRL 226 >3G01-A nrPDB Length = 227 Score = 143 bits (360), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 84/233 (36%), Positives = 124/233 (53%), Gaps = 19/233 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSH-FCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG+E PHSRPYMA + G FCGG L+ FVLTAAHC R + V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AHN++ +E TQQ VA+ + +Y+ +++ ND++L++L A + +V + LP+++ Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV----------VTFFCRPHNICTFVPRRK 195 V G +C GWG+V + L E+ +TV + + R + IC + K Sbjct: 117 VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIK 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 GDSGGPL+C GI V +G P FTRV +V WI+ T++ Sbjct: 177 GASFRGDSGGPLVCKRAAAGI---VSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >4AN7-A nrPDB Length = 231 Score = 142 bits (358), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/232 (37%), Positives = 130/232 (56%), Gaps = 22/232 (9%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +IVGG+ +S PY SL N GSHFCGG+LI+ +V++AAHC + + V LG Sbjct: 8 KIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYK----SRIQVRLG 59 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 HN+ E +Q + A++ + N++ ND++LI+LSSPA L++ VATV LP+ Sbjct: 60 EHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SC 117 Query: 146 VPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVT-FFCRP--------HNICTFVPRRK 195 GT+CL GWG + +LQ L V++ C+ + IC Sbjct: 118 AAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGG 177 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QGI S+ +GCA + P +T+V YV+WI+ T+ Sbjct: 178 KDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTI 228 >1A0J-A nrPDB Length = 223 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 86/231 (37%), Positives = 130/231 (56%), Gaps = 22/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+E + +S Y ASLQ G HFCGG+LI ++V++AAHC + Q V LG Sbjct: 1 IVGGYECRKNSASYQASLQ----SGYHFCGGSLISSTWVVSAAHCYKSRIQ----VRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E T+Q +V ++ +Y++ N ND++LI+LS PA+L++ V+TV LP Sbjct: 53 HNIAVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALP--SSCA 110 Query: 147 PHGTQCLAMGWGRV-GAHDPPAQVLQELNVTVV-TFFCR--------PHNICTFVPRRKA 196 GT+CL GWG + G+ L+ L++ ++ + C + C Sbjct: 111 SSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QG+ S+ +GCA R P +T+V Y WI ST+ Sbjct: 171 DSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTM 220 >1FDP-A nrPDB Length = 235 Score = 139 bits (349), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 126/234 (53%), Gaps = 17/234 (7%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 I+GG EA+ H+RPYMAS+Q+ G +H CGG L+ +VL+AAHCL D V V+L Sbjct: 6 GRILGGREAEAHARPYMASVQLNG---AHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLL 62 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN-DVLLIQLSSPANLSASVATVQLPQQDQ 144 GAH++ EP+++ + V + + + ++ D+LL+QLS A L +V + + D+ Sbjct: 63 GAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDR 122 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---TFFCRPHN--------ICTFVPR 193 V GT C GWG V LQ + + V+ T R H+ +C R Sbjct: 123 DVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNR 182 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 R + C GDSGGPL+C G+++G+ + C R P +TRVA Y WI S L Sbjct: 183 RDS--CKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >5C67-A nrPDB Length = 224 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 89/235 (37%), Positives = 130/235 (55%), Gaps = 30/235 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + +S PY SL N GSHFCGG+LI +V++AAHC + + V LG Sbjct: 1 IVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCYK----TRIQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ E +Q + A++ + Y+ + ND++LI+LSSPA ++A V+T+ LP P Sbjct: 53 HNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT--APP 110 Query: 147 PHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVVT-FFCR---PHNI-----CTFVPRR 194 GT+CL GWG GA P L+ L+ V+T C+ P I C Sbjct: 111 AAGTECLISGWGNTLSFGADYPDE--LKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTL 247 C D+GGP++C+G +QG+ V W GCA + P +T+V YVDWI+ T+ Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGV---VSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >4Q7Y-A nrPDB Length = 250 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 124/234 (52%), Gaps = 15/234 (6%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHE PHSRPYMAS++ G H CGG L+ +V++AAHC R VVLGA Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 57 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLP-QQDQP 145 H + T EPTQQ F + + + +Y ND+ L++L+ A L +V ++LP ++ +P Sbjct: 58 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARP 117 Query: 146 VPHGTQCLAMGWGRVGAHD--PPAQV---LQELNVTVVTFFCRPHNICTFVPRR-----K 195 GT+C GWG V + PP + ++ L+ V + H T + R + Sbjct: 118 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 177 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 G C DSGGPL+C G+ SF C PD +T+V+ +V WI +RR Sbjct: 178 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 >2EEK-A nrPDB Length = 220 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 120/230 (52%), Gaps = 21/230 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+E HS+ + SL N G HFCGG+L+ +V++AAHC + + + V LG Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCYKSV----LRVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H++R E T+Q+ S + V + NY + N ND++LI+L+ PA L+ V V LP + Sbjct: 53 HHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--ECA 110 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKAG 197 T C GWG + LQ L++ +++ C Sbjct: 111 ADATMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKD 170 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G++QG+ S+ +GCA R P + +V + W+R T+ Sbjct: 171 SCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTM 219 >1AZZ-A nrPDB Length = 226 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 89/228 (39%), Positives = 119/228 (52%), Gaps = 18/228 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG EA P+S P+ A+L + +FCGG+LI P ++LTAAHC+ V+VVLGA Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDG--AGFVDVVLGA 55 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+R E TQ + NY++ ND+ +I+L P L+A++ATV LP D V Sbjct: 56 HNIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV 115 Query: 147 PHGTQCLAMGWG-----RVGAHDPPAQV----LQELNVTVVTFFCRPHNICTFVPRRKAG 197 GT GWG +G D QV + + V NIC K G Sbjct: 116 --GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICIDSTGGK-G 172 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GDSGGPL +G+ GI SF +PD FTRV ++DWI++ Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQT 220 >4WWY-A nrPDB Length = 224 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 127/234 (54%), Gaps = 28/234 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + +S PY SL N G HFCGG+LI+ +V++A HC + + V LG Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCYKS----RIQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E +Q + A++ + YD + ND++LI+LSS A ++A V+T+ LP P Sbjct: 53 HNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPT--APP 110 Query: 147 PHGTQCLAMGWGRVGAH--DPPAQVLQELNVTVVT-FFCR---PHNI-----CTFVPRRK 195 GT+CL GWG + D P + LQ L+ V++ C P I C Sbjct: 111 ATGTKCLISGWGNTASSGADYPDE-LQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGG 169 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTL 247 C DSGGP++C+G +QG+ V W GCA + P +T+V YV WI++T+ Sbjct: 170 KDSCQRDSGGPVVCNGQLQGV---VSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >2ZKS-A nrPDB Length = 240 Score = 129 bits (323), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 90/238 (37%), Positives = 117/238 (49%), Gaps = 24/238 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 85 I+GG E PHSRPYMASLQ G SH CGG L+HP +VLTAAHCL QR+ + +VL Sbjct: 1 IIGGREVIPHSRPYMASLQRNG---SHLCGGVLVHPKWVLTAAHCL---AQRMAQLRLVL 54 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSPANLSASVATVQLPQQDQ 144 G H + P A + Y L ND+ L+QL S ++ + LP + Q Sbjct: 55 GLHTL--DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQ 112 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR----------PHNICTFVPR 193 V GT+C GWG ++VL+EL++ V+ T C P +C Sbjct: 113 VVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADS 172 Query: 194 RKAGICFGDSGGPLICDG--IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 + C GDSGGPL+C ++ G+ SF C P T VA YV WIR R Sbjct: 173 KDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGR 230 >5FXL-A nrPDB Length = 246 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 89/254 (35%), Positives = 132/254 (51%), Gaps = 34/254 (13%) Query: 13 VLLALLLSGAARA------AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFV 66 + LALL GAA A +IVGG+ ++ PY SL N G HFCGG+LI+ +V Sbjct: 5 IFLALL--GAAVAFPVDDDDKIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWV 58 Query: 67 LTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLS 125 ++AAHC + Q V LG N+ E +Q S ++ ++ +Y++ ND++LI+L Sbjct: 59 VSAAHCYKSGIQ----VRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLK 114 Query: 126 SPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVT-FFCR 183 S A+L++ VA++ LP GTQCL GWG + VL+ L +++ C+ Sbjct: 115 SAASLNSRVASISLPT--SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCK 172 Query: 184 --------PHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFF 233 + C C GDSGGP++C G +QGI V W GCA + P + Sbjct: 173 SAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGI---VSWGSGCAQKNKPGVY 229 Query: 234 TRVALYVDWIRSTL 247 T+V YV WI+ T+ Sbjct: 230 TKVCNYVSWIKQTI 243 >3QUM-P nrPDB Length = 237 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 124/246 (50%), Gaps = 39/246 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + HS+P+ + RG CGG L+HP +VLTAAHC+R+ ++LG Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRA---VCGGVLVHPQWVLTAAHCIRNKSV----ILLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YD-----------AENKLNDVLLIQLSSPANLSASVA 135 H++ E T Q F V+ F + YD ++ +D++L++LS PA L+ +V Sbjct: 54 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 195 + LP Q+ + GT C A GWG + P + L + V +++C V +K Sbjct: 114 VMDLPTQEPAL--GTTCYASGWGSI----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 167 Query: 196 A--------------GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C GDSGGPL+C+G++QGI S+ CA P +T+V Y Sbjct: 168 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 227 Query: 242 WIRSTL 247 WI+ T+ Sbjct: 228 WIKDTI 233 >1MZD-A nrPDB Length = 240 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 122/241 (50%), Gaps = 28/241 (11%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC-LRDIPQRLVNVVL 85 EI+GG E PHSRP+MAS+Q G+ H CGG LI P +VLTAAHC R + VVL Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGH---HVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 86 GAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 GAH++ E ++Q + + + ++ + ND++L++L + A L+ V + + + Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 117 Query: 145 PVPHGTQCLAMGWGRVGAHDP----PAQVLQELNVTVVTF-------------FCRPHNI 187 + GT+C GW GA DP P+ L+E+ VTV++ F + Sbjct: 118 SLRSGTKCKVTGW---GATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMV 174 Query: 188 CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVA-LYVDWIRST 246 C + + C GD+GGPLIC G+ I S C P +T + Y WI+S Sbjct: 175 CAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGG-HECGVATKPGIYTLLTKKYQTWIKSN 233 Query: 247 L 247 L Sbjct: 234 L 234 >4NFE-A nrPDB Length = 237 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 124/246 (50%), Gaps = 39/246 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + HS+P+ ++ G CGG L+HP +VLTAAHCL+ Q V LG Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWA---HCGGVLVHPQWVLTAAHCLKKNSQ----VWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVF---LNNYD---------AENKLNDVLLIQLSSPANLSASVA 135 HN+ E T Q V+ F L N E+ +D++L++LS PA ++ V Sbjct: 54 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 195 + LP Q+ + GT C A GWG + P + L+ ++ V+ +++C K Sbjct: 114 VLGLPTQEPAL--GTTCYASGWGSI----EPEEFLRPRSLQCVSLHLLSNDMCARAYSEK 167 Query: 196 -------AGI-------CFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 AG+ C GDSGGPL+C+G++QGI S+ CA P +T+V Y Sbjct: 168 VTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRK 227 Query: 242 WIRSTL 247 WI+ T+ Sbjct: 228 WIKDTI 233 >2TLD-E nrPDB Length = 220 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 84/231 (36%), Positives = 126/231 (54%), Gaps = 25/231 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ ++ PY SL N G HFCGG+LI+ +V++AAHC + Q V LG Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYKSGIQ----VRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 N+ E +Q S ++ ++ +Y++ ND++LI+L S A+L++ VA++ LP Sbjct: 53 DNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCA 110 Query: 147 PHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVT-FFCR---PHNICT--FVPRRKAG-I 198 GTQCL GWG + VL+ L +++ C+ P I + F + G Sbjct: 111 SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGGDS 170 Query: 199 CFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C G +QGI V W GCA + P +T+V YV WI+ T+ Sbjct: 171 CQGDSGGPVVCSGKLQGI---VSWGSGCA-KNKPGVYTKVCNYVSWIKQTI 217 >5UGG-A nrPDB Length = 251 Score = 124 bits (310), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 87/239 (36%), Positives = 118/239 (49%), Gaps = 25/239 (10%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVV 84 +VGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL P+ V+ Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 77 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 LGAH EP Q V+++FL E D+ L++LSSPA ++ V LP + Sbjct: 78 LGAHQEVNLEPHVQEIEVSRLFL-----EPTRKDIALLKLSSPAVITDKVIPACLPSPNY 132 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH----------NICTFVPR 193 V T+C GWG A +L+E + V+ C + +C Sbjct: 133 VVADRTECFITGWGETQGTF-GAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 191 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C I+QG+ S+ + GCA P + RV+ +V WI +R Sbjct: 192 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 249 >5FCR-A nrPDB Length = 234 Score = 123 bits (309), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 83/234 (35%), Positives = 123/234 (52%), Gaps = 24/234 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI-PQRLVNVVLG 86 I+GG EA H+RPYMAS+Q+ G +H CGGTL+ +VL+AAHC+ + V V+LG Sbjct: 1 ILGGQEAAAHARPYMASVQVNG---THVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH++ EP ++ + V V + + L +D++L +LS A+L V + L +D+ Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---TFFCRPHN--------ICTFVPRR 194 V GT C GWG V VL +L V+++ T R ++ +C RR Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRR 177 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWG---CATRLFPDFFTRVALYVDWIRS 245 C GDSG PL+C ++G+ V WG C P +TRV+ Y WI + Sbjct: 178 DT--CRGDSGSPLVCGDAVEGV---VTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 >1BRU-P nrPDB Length = 241 Score = 123 bits (308), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 85/240 (35%), Positives = 123/240 (51%), Gaps = 22/240 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGN-PGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG +A+P+S P+ SLQ + H CGGTL+ S+VLTAAHC+ R VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISS--SRTYRVVLG 58 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKL---NDVLLIQLSSPANLSASVATVQLPQQD 143 H++ T EP V+++ ++ N+L ND+ L++L+SP +L+ + LP Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFC--RPHNICTFVPRR-----KA 196 +P+ C GWGR+ + +LQ+ + VV + +P + V Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGD 178 Query: 197 GI---CFGDSGGPLICDGI-----IQGIDSF-VIWGCATRLFPDFFTRVALYVDWIRSTL 247 GI C GDSGGPL C G + GI SF GC P FTRV+ Y+DWI S + Sbjct: 179 GIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 >1ORF-A nrPDB Length = 234 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 120/237 (50%), Gaps = 22/237 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG+E PHSRPYM L + C G LI +VLTAAHC ++ +R V+LGA Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHC--NLNKR-SQVILGA 54 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H++ +EPT+Q V + F YD + D+ L+QL+ A ++ V + LP++ V Sbjct: 55 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDV 114 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHNICTFVP------------R 193 GT C GWGR + L+E+ +T++ C N F P R Sbjct: 115 KPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 174 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWG-CATRLFPDFFTRVA-LYVDWIRSTLR 248 C GDSG PL+C+G+ +G+ SF + C P + ++ +++WI T++ Sbjct: 175 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1GVZ-A nrPDB Length = 237 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 127/245 (51%), Gaps = 33/245 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHF-CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG E + HS+P+ ++ +G HF CGG L+HP +VLTAAHC+ D Q + LG Sbjct: 1 IIGGWECEKHSKPWQVAVYHQG----HFQCGGVLVHPQWVLTAAHCMSDDYQ----IWLG 52 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYD-----------AENKLNDVLLIQLSSPANLSASV 134 HN+ E T Q V+ FL+ +D ++ +D++L++L+ PA ++ +V Sbjct: 53 RHNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAV 112 Query: 135 ATVQLPQQDQPVPHGTQCLAMGWGRVGAH-DPPAQVLQ--ELNVTVVTFFCR--PHNICT 189 + LP Q+ + G+ C GWG + + + LQ EL + R P + Sbjct: 113 KILDLPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTE 170 Query: 190 FV----PRRKAG-ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 FV R +G IC GDSGG LICDG+ QGI S+ CA FT+V + WI+ Sbjct: 171 FVLCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIK 230 Query: 245 STLRR 249 T+ + Sbjct: 231 ETIEK 235 >4DUR-A nrPDB Length = 791 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 118/239 (49%), Gaps = 25/239 (10%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVV 84 +VGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL P+ V+ Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 617 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 LGAH EP Q V+++FL E D+ L++LSSPA ++ V LP + Sbjct: 618 LGAHQEVNLEPHVQEIEVSRLFL-----EPTRKDIALLKLSSPAVITDKVIPACLPSPNY 672 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH----------NICTFVPR 193 V T+C GWG A +L+E + V+ C + +C Sbjct: 673 VVADRTECFITGWGETQG-TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 731 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C I+QG+ S+ + GCA P + RV+ +V WI +R Sbjct: 732 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 789 >4H4F-A nrPDB Length = 249 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 85/240 (35%), Positives = 126/240 (52%), Gaps = 21/240 (8%) Query: 28 IVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG +A+PHS P+ SLQ ++ + H CGGTLI +FVLTAAHC+ + R V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 58 Query: 87 AHNVRTQEPTQQHF-SVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 +N+ ++ F V + ++ ++A ND+ LI+L+ LS ++ LP++D Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQE-LNVTVVTFFCRPHNICTFVPRRK---AG--- 197 +P C GWGR+ + P A LQ+ L V C + F ++ AG Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 178 Query: 198 ---ICFGDSGGPLIC---DGIIQ--GIDSF-VIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL C +G + GI SF GC TR P +TRV+ Y+DWI ++ Sbjct: 179 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >1ELT-A nrPDB Length = 236 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/243 (33%), Positives = 122/243 (50%), Gaps = 30/243 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMR-GNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG AQP+S P+ SLQ + G+ H CGG+LI +V+TAAHC+ R VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS--ARTWRVVLG 58 Query: 87 AHNVRTQEPTQQHFSVAQVFLN---NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 HN+ T E +Q +V VF++ N D D+ L++L++ A+L+++V LP + Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGI----- 198 Q +P+ C GWG+ P + L++ + V H C+ + + Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSV-----DHATCSSSGWWGSTVKTTMV 173 Query: 199 ---------CFGDSGGPLIC--DG--IIQGIDSFV-IWGCATRLFPDFFTRVALYVDWIR 244 C GDSGGPL C +G + G+ SFV GC P FTRV+ Y+ W+ Sbjct: 174 CAGGGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMN 233 Query: 245 STL 247 + Sbjct: 234 GIM 236 >5MS3-A nrPDB Length = 228 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 116/237 (48%), Gaps = 30/237 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GGHE QPHS+P+ A+L +G CGG L+ ++VLTAAHC + P+ V LG Sbjct: 1 VLGGHECQPHSQPWQAAL-FQGQ--QLLCGGVLVGGNWVLTAAHCKK--PKYTVR--LGD 53 Query: 88 HNVRTQEPTQQHFSVAQVF----LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 H+++ ++ +Q V Q N+ D E+ +D++L+QL A+L + V + L D Sbjct: 54 HSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLA--D 111 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFV------------ 191 G +C GWG V + P LN V F P C Sbjct: 112 HCTQPGQKCTVSGWGTVTS--PRENFPDTLNCAEVKIF--PQKKCEDAYPGQITDGMVCA 167 Query: 192 -PRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + A C GDSGGPL+CDG +QGI S+ C P +T + Y+DWI+ + Sbjct: 168 GSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >1PYT-D nrPDB Length = 251 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 87/242 (35%), Positives = 122/242 (50%), Gaps = 20/242 (8%) Query: 25 AAEIVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 +A +VGG +A PHS P+ SLQ +R N H CGGTLI P+ VLTAAHC+ + V Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNT--LTYRV 68 Query: 84 VLGAHNVRTQ-EPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQ 141 LG +N+ + E + V +F+ +++ ND+ LI+L+ L ++ LP Sbjct: 69 ALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPS 128 Query: 142 QDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRPHNIC------TFVPRR 194 + +P C GWGR+ + P A LQ+ VV + C + T V Sbjct: 129 EGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCAG 188 Query: 195 KAGI---CFGDSGGPLIC--DG--IIQGIDSF-VIWGCATRLFPDFFTRVALYVDWIRST 246 G+ C GDSGGPL C DG ++GI SF C T P FTRV+ Y+DWI Sbjct: 189 GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQK 248 Query: 247 LR 248 L+ Sbjct: 249 LQ 250 >1SPJ-A nrPDB Length = 238 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 85/251 (33%), Positives = 124/251 (49%), Gaps = 48/251 (19%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHF----CGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 IVGG E + HS+P+ A+L HF CGG L+H +VLTAAHC+ D Q + Sbjct: 1 IVGGWECEQHSQPWQAALY-------HFSTFQCGGILVHRQWVLTAAHCISDNYQ----L 49 Query: 84 VLGAHNVRTQEPTQQHFSVAQVF---------LNNYD---AENKLNDVLLIQLSSPAN-L 130 LG HN+ E T Q V++ F L N+ E+ +D++L++L+ PA+ + Sbjct: 50 WLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTI 109 Query: 131 SASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHD--------------PPAQVLQELNVT 176 + +V V+LP ++ V G+ CLA GWG + + P ++ +V Sbjct: 110 TDAVKVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ 167 Query: 177 VVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRV 236 VT F +C C GDSGGPL+CDG++QG+ S+ C T P RV Sbjct: 168 KVTDFM----LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRV 223 Query: 237 ALYVDWIRSTL 247 YV WI T+ Sbjct: 224 LSYVKWIEDTI 234 >5LHN-A nrPDB Length = 247 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 126/250 (50%), Gaps = 34/250 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMR---GNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVV 84 IVGG + ++P+ A++ + G+P S CGG+LI P +V +AAHC +P++ VV Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 85 -LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKL---NDVLLIQLSSP----ANLSASVAT 136 LG + P + F V Q+ L+ Y E+ L ND+ L+++ + A S S+ T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFC-----RPHN----- 186 + LP + P G+ C G+G+ D + L ++VV +PH Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESD--YLYPKNLKMSVVKLVSHEQCMQPHYYGSEI 178 Query: 187 ----ICTFVPRRKAGICFGDSGGPLICDGIIQG---IDSFVIW--GCATRLFPDFFTRVA 237 +C P K C GDSGGPLIC+ I+G + V W GCA + P +TRV+ Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICN--IEGRPTLSGIVSWGRGCAEKNKPGVYTRVS 236 Query: 238 LYVDWIRSTL 247 ++DWI+S + Sbjct: 237 HFLDWIQSHI 246 >1NPM-A nrPDB Length = 225 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 80/237 (33%), Positives = 117/237 (49%), Gaps = 30/237 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G E PHS+P+ A+L +G CGG L+ +VLTAAHC + + +V LG Sbjct: 1 ILEGRECIPHSQPWQAAL-FQGE--RLICGGVLVGDRWVLTAAHCKK----QKYSVRLGD 53 Query: 88 HNVRTQEPTQQHFSVAQVF----LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 H++++++ +Q VAQ NN + E+ +D++LI+L + ANL V VQL Sbjct: 54 HSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLC 113 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK-------- 195 V G +C+ GWG V + P LN V + N C K Sbjct: 114 PKV--GQKCIISGWGTVTS--PQENFPNTLNCAEVKIY--SQNKCERAYPGKITEGMVCA 167 Query: 196 -----AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 A C GDSGGPL+CDG++QGI S+ C P +T++ Y WI+ T+ Sbjct: 168 GSSNGADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1TON-A nrPDB Length = 235 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 123/249 (49%), Gaps = 43/249 (17%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG++ + +S+P+ ++ + CGG LI PS+V+TAAHC + Q V+LG Sbjct: 1 IVGGYKCEKNSQPWQVAVI-----NEYLCGGVLIDPSWVITAAHCYSNNYQ----VLLGR 51 Query: 88 HNVRTQEPTQQHFSVAQVF--------LNNYDAENKL----NDVLLIQLSSPANLSASVA 135 +N+ EP Q V Q F + D E + ND++L+ LS PA+++ V Sbjct: 52 NNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVK 111 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGR------VGAHDPPAQVLQELNV-------TVVTFFC 182 + LP ++ V G+ CLA GWG V +HD LQ +N+ + T+ Sbjct: 112 VIDLPTKEPKV--GSTCLASGWGSTNPSEMVVSHD-----LQCVNIHLLSNEKCIETYKD 164 Query: 183 RPHNICTFVPRRKAG--ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 ++ + G C GDSGGPLICDG++QGI S CA P + ++ + Sbjct: 165 NVTDVMLCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFT 224 Query: 241 DWIRSTLRR 249 WI+ ++ Sbjct: 225 SWIKKVMKE 233 >1SGF-G nrPDB Length = 237 Score = 113 bits (283), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 120/252 (47%), Gaps = 47/252 (18%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + + +S+P+ ++ + CGG L+ P++VLTAAHC D V LG Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYT---QYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGK 53 Query: 88 HNVRTQEPTQQHFSVAQV----------------FLNNYDAENKLNDVLLIQLSSPANLS 131 +N+ EP+ QH V++ FL YD N D++L++LS PA+++ Sbjct: 54 NNLFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLE-YDYSN---DLMLLRLSKPADIT 109 Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFV 191 +V + LP ++ + G+ CLA GWG + P + ++ V P+ C Sbjct: 110 DTVKPITLPTEEPKL--GSTCLASGWGSI----TPTKFQFTDDLYCVNLKLLPNEDCAKA 163 Query: 192 PRRK--------------AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVA 237 K C GDSGGPLICDG++QGI S+ C P +T++ Sbjct: 164 HIEKVTDAMLCAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLN 223 Query: 238 LYVDWIRSTLRR 249 + WI+ T+ + Sbjct: 224 KFTSWIKDTMAK 235 >2CGA-A nrPDB Length = 245 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 83/248 (33%), Positives = 123/248 (49%), Gaps = 32/248 (12%) Query: 18 LLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC---LR 74 +LSG +R IV G EA P S P+ SLQ + G HFCGG+LI+ ++V+TAAHC Sbjct: 9 VLSGLSR---IVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHCGVTTS 63 Query: 75 DIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSAS 133 D+ VV G + + Q +A+VF N+ Y++ ND+ L++LS+ A+ S + Sbjct: 64 DV------VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQT 117 Query: 134 VATVQLPQQDQPVPHGTQCLAMGWG--RVGAHDPPAQVLQELNVTVVTFFCRPH------ 185 V+ V LP GT C+ GWG R + P ++ Q + C+ + Sbjct: 118 VSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIK 177 Query: 186 --NICTFVPRRKAGICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVALY 239 IC + C GDSGGPL+C + GI S+ C+T P + RV Sbjct: 178 DAMICAGASGVSS--CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTST-PGVYARVTAL 234 Query: 240 VDWIRSTL 247 V+W++ TL Sbjct: 235 VNWVQQTL 242 >2V35-A nrPDB Length = 240 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 125/241 (51%), Gaps = 25/241 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMR-GNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVVL 85 +VGG EAQ +S P SLQ R G+ +H CGGTLI ++V+TAAHC+ R++ R VV+ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFR---VVV 57 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN---NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 G HN+ + T+Q+ V ++ ++ N D D+ L++L+ L++ V LP+ Sbjct: 58 GEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRA 117 Query: 143 DQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRPHN----------ICTFV 191 + + + C GWG + AQ LQ+ + V + C + +C Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG 177 Query: 192 PRRKAGICFGDSGGPLIC--DG--IIQGIDSFVI-WGCATRLFPDFFTRVALYVDWIRST 246 ++G C GDSGGPL C +G + G+ SFV GC P FTRV+ Y+ WI + Sbjct: 178 DGVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNV 236 Query: 247 L 247 + Sbjct: 237 I 237 >1FIZ-A nrPDB Length = 263 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 117/249 (46%), Gaps = 30/249 (12%) Query: 28 IVGGHEAQPHSRPYMASLQM---RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ----RL 80 +VGG A+P + P+M SLQ+ N H CGG L++ +VLTAAHC ++ + RL Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 81 V---NVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATV 137 + N V+ N + P Q+ F + Y + ++ND+ LI+++ P + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 138 QLPQQDQPVPHGTQ-CLAMGWGRVGAHDP-PAQVLQELNVTVVTF-FC----------RP 184 LPQ P Q C GWG + P + LQE V ++ C R Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDG------IIQGIDSFVIWGCATRLFPDFFTRVAL 238 N+C PR K C GDSGGPL+C ++ GI S+ + GCA P +T Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTWP 239 Query: 239 YVDWIRSTL 247 Y++WI S + Sbjct: 240 YLNWIASKI 248 >5TJX-A nrPDB Length = 263 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 113/249 (45%), Gaps = 21/249 (8%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRL 80 + IVGG E+ P+ SLQ++ H CGG+LI +VLTAAHC +P R+ Sbjct: 13 STRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 72 Query: 81 VNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLP 140 + +L ++ P Q + + NY +D+ LI+L +P + + LP Sbjct: 73 YSGILELSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLP 130 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTF 190 + T C GWG +LQ++N+ +VT + +C Sbjct: 131 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 190 Query: 191 VPRRKAGICFGDSGGPLIC--DGIIQ--GIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 C GDSGGPL+C +G+ + GI S+ GCA R P +T+VA Y+DWI Sbjct: 191 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEK 249 Query: 247 LRRVEAKGR 255 + + K + Sbjct: 250 TQSSDGKAQ 258 >3S9B-A nrPDB Length = 234 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 76/237 (32%), Positives = 116/237 (48%), Gaps = 30/237 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG E + P++ +L + H C G LI+ +VLTAAHC R R + + LG Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCDR----RNIRIKLGM 55 Query: 88 H--NVRTQE-----PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLP 140 H N+R ++ P ++F + F N D D++LI+L P S +A V LP Sbjct: 56 HSKNIRNEDEQIRVPRGKYFCLNTKFPNGLD-----KDIMLIRLRRPVTYSTHIAPVSLP 110 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRP---------HNICTF 190 + + V G++C MGWG++ P V N+ +V +C P +C Sbjct: 111 SRSRGV--GSRCRIMGWGKISTTTYP-DVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAG 167 Query: 191 VPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + + C GDSGGPLIC+G + GI + C L P +T+V Y +WI+S + Sbjct: 168 ILKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >1LTO-A nrPDB Length = 245 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/242 (33%), Positives = 118/242 (48%), Gaps = 31/242 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 85 IVGG EA P+ SL++R HFCGG+LIHP +VLTAAHCL + L + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 ++ Q+ Q V+++ ++ + D+ L++L P N+S+ V TV LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 145 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVV-TFFC-----------------RP 184 P G C GWG V + PP L+++ V ++ C R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-W--GCATRLFPDFFTRVALYVD 241 +C +R + C GDSGGPL+C + + V+ W GCA P +TRV Y+D Sbjct: 178 DMLCAGNSQRDS--CKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLD 235 Query: 242 WI 243 WI Sbjct: 236 WI 237 >5ZFH-A nrPDB Length = 224 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 69/232 (29%), Positives = 114/232 (49%), Gaps = 22/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G++ + S P+ +L ++GN CGG L+ +VLTAAHC Q V LG+ Sbjct: 1 IIDGYKCKEGSHPWQVAL-LKGN--QLHCGGVLVDKYWVLTAAHCKMGQYQ----VQLGS 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + Q + Q + F + Y + +ND++L++L P +S+ V VQLP+ +P Sbjct: 54 DKIGDQ--SAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEPP 111 Query: 147 PHGTQCLAMGWGRVGAHDP--PAQVLQELNVTVVTFFCRP--------HNICTFVPRRKA 196 GT C GWG + D P+ ++ + + C+ +C +P K Sbjct: 112 --GTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKT 169 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C+ +QG+ S+ + C P +T+V Y W+ T++ Sbjct: 170 NTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >3W94-A nrPDB Length = 235 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 75/239 (31%), Positives = 110/239 (46%), Gaps = 22/239 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL--RDIPQRLVNVVL 85 +VGG A+ + P+M SL RG H CG +LI ++LTAAHC+ ++ + + VL Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGR---HGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 86 GAHNVRTQEPTQ-QHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H + + Q V ++ +N NY+ K D+ ++ L P N + V V L +D Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICTFVPR 193 Q P G +C GWGR +LQE V +V + +C P Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPE 177 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C + G+ SF + GC P + RV+ + WI T R Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWIAETRR 235 >4MPW-A nrPDB Length = 245 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 118/242 (48%), Gaps = 31/242 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 85 IVGG EA P+ SL++ G HFCGG+LIHP +VLTAAHC+ + L + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN-DVLLIQLSSPANLSASVATVQLPQQDQ 144 ++ Q+ Q V+++ ++ ++ D+ L++L P +S+ V TV LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 145 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVV-TFFC-----------------RP 184 P G C GWG V + PP L+++ V ++ C R Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-W--GCATRLFPDFFTRVALYVD 241 +C RR + C GDSGGPL+C + + V+ W GCA P +TRV Y+D Sbjct: 178 DMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 235 Query: 242 WI 243 WI Sbjct: 236 WI 237 >1AO5-A nrPDB Length = 237 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 120/248 (48%), Gaps = 39/248 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG + +S+P+ ++ + H CGG L+ ++VLTAAHC D V LG Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYVD----QYEVWLGK 53 Query: 88 HNVRTQEPTQQH-----------FSVAQVFLNNYD-AENKLNDVLLIQLSSPANLSASVA 135 + + +EP+ QH F+++ + L + +D++L++LS PA+++ V Sbjct: 54 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 195 + LP + +P P G++CLA GWG + P + + ++ V P+ C V +K Sbjct: 114 PIALPTK-EPKP-GSKCLASGWGSI----TPTRWQKPDDLQCVFITLLPNENCAKVYLQK 167 Query: 196 A--------------GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C DSGGPLICDGI+QG S+ C P +T + + Sbjct: 168 VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNS 227 Query: 242 WIRSTLRR 249 WI+ T+ + Sbjct: 228 WIKDTMMK 235 >6I44-A nrPDB Length = 627 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 116/250 (46%), Gaps = 23/250 (9%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRL 80 + IVGG ++ P+ SLQ++ H CGG+LI +VLTAAHC +P R+ Sbjct: 377 STRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 436 Query: 81 VNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQL 139 + +L ++ P Q + ++ ++ NY +D+ LI+L +P + + L Sbjct: 437 YSGILQLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICL 493 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICT 189 P + T C GWG +LQ++N+ +VT + +C Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 553 Query: 190 FVPRRKAGICFGDSGGPLIC--DGI--IQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GD+GGPL+C +G+ + GI S+ GCA R P +T+VA Y+DWI Sbjct: 554 GYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILE 612 Query: 246 TLRRVEAKGR 255 + + K + Sbjct: 613 KTQSSDGKAQ 622 >1FON-A nrPDB Length = 240 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 81/239 (33%), Positives = 115/239 (48%), Gaps = 25/239 (10%) Query: 31 GHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHN 89 G +A P+S + SLQ + H CGG+LI P +V+TA HC+ R VVLG ++ Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCIS--TSRTYQVVLGEYD 59 Query: 90 VRTQEPTQQHFSV--AQVF---LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 E ++Q + +F L N + ND+ L++LS A L V LP Sbjct: 60 RSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 145 PVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFFCRPHNICTFVPRR--------- 194 +P+ C GWGR+ P P ++ Q L TV C + ++ Sbjct: 120 ILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT 179 Query: 195 KAGICFGDSGGPLIC---DGIIQ--GIDSFV-IWGCATRLFPDFFTRVALYVDWIRSTL 247 ++G C GDSGGPL C DG Q G+ SFV +GC T P FTRV+ ++DWI T+ Sbjct: 180 RSG-CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >2BDH-A nrPDB Length = 223 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 105/231 (45%), Gaps = 19/231 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G + PHS+P+ A+L M FC G L+HP +VL+AAHC Q + LG Sbjct: 1 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCF----QNSYTIGLGL 53 Query: 88 HNVRT-QEPTQQHFSVA-QVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H++ QEP Q + V Y+ ND++LI+L + S ++ ++ + Q Sbjct: 54 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFC--------RPHNICTFVPRRKAG 197 G CL GWG + P + V C P C + + Sbjct: 114 A--GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKD 171 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPLIC+G +QG+ SF C P +T + + +WI T++ Sbjct: 172 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1FXY-A nrPDB Length = 228 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 79/234 (33%), Positives = 114/234 (48%), Gaps = 24/234 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + P+ A L N G FCGGT++ ++LTAAHCL + V V G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG--FCGGTILSEFYILTAAHCLYQAKRFKVRV--GD 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 N +E + V V +N + E D+ +++L +P +VA LP P Sbjct: 57 RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPT--APP 114 Query: 147 PHGTQCLAMGWGRVGAH--DPPAQVLQELNVTVVT-FFCR---PHNI-----CTFVPRRK 195 GT+CL GWG + D P + LQ L+ V++ C P I C Sbjct: 115 ATGTKCLISGWGNTASSGADYPDE-LQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGG 173 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QG+ V W GCA + P +T+V YV WI++T+ Sbjct: 174 KDSCQGDSGGPVVCNGQLQGV---VSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >5XRF-A nrPDB Length = 242 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 117/236 (49%), Gaps = 26/236 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG+E + ++A+ P + C GTLIH +VL AAHC + R +N+ LG Sbjct: 7 VIGGNECDTNEHRFLAAF-FTSRPWTFQCAGTLIHEEWVLAAAHCYK----RGLNIYLGM 61 Query: 88 HNVRTQ-EPTQQHFSVAQVFLNNYDAENKL----NDVLLIQLSSPANLSASVATVQLPQQ 142 HN Q + Q+ +++ + + Y + KL DV+L++L+ P + S +A + LP Sbjct: 62 HNQSIQFDDEQRRYAIEEHY---YRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSS 118 Query: 143 DQPVPHGTQCLAMGWGRVGA-HDPPAQVLQELNVTVVTFF-CRPHN---------ICTFV 191 + G+ C MGWG + + D V N+ ++ + C H +C V Sbjct: 119 PPSI--GSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 192 PRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C DSGGPLICDG QGI F + CA P +TRV+ Y DWI++ + Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >1SGF-A nrPDB Length = 240 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 71/218 (32%), Positives = 105/218 (48%), Gaps = 36/218 (16%) Query: 56 CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQV---------F 106 CGG L+ ++VLTAAHC D Q V LG +N EP+ QH V++ Sbjct: 29 CGGVLLDRNWVLTAAHCYNDKYQ----VWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSL 84 Query: 107 LNNYD---AENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAH 163 LN + ++ ND++L++LS PA+++ V + LP ++ + G+ CLA GWG Sbjct: 85 LNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL--GSTCLASGWGSTT-- 140 Query: 164 DPPAQVLQELNVTVVTFFCRPHNICTFVPRRK---AGICFG-----------DSGGPLIC 209 P + ++ V P+ C K A +C G DSGGPLIC Sbjct: 141 --PIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLIC 198 Query: 210 DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 DGI+QGI S+ C P +T++ + WIR T+ Sbjct: 199 DGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 236 >5GVT-A nrPDB Length = 250 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 69/234 (29%), Positives = 102/234 (43%), Gaps = 21/234 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRLVNV 83 IVGG A P+ SLQ++ +H CGG++I +VLTAAHC IP R+ Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 +L + + P+ + + + Y D+ LI+L +P N + + LP + Sbjct: 61 ILSLSEITKETPSSRIKEL--IIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKA 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICTFVPR 193 T C GWG +LQ+ + +V + IC Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKE 178 Query: 194 RKAGICFGDSGGPLICD--GIIQ--GIDSFVIWGCATRLFPDFFTRVALYVDWI 243 C GDSGGPL+C G Q GI S+ GCA + P +T+V+ Y+DWI Sbjct: 179 GGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEYMDWI 231 >1FIW-A nrPDB Length = 290 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 118/250 (47%), Gaps = 32/250 (12%) Query: 28 IVGGHEAQPHSRPYMASLQM---RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVN-- 82 I+GG +A + P+M SLQ+ N H CGG+L++ ++LTAAHC R I +++ + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFR-IKKKVTDWR 59 Query: 83 VVLGAHNVR------TQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVAT 136 ++ GA V + P Q+ + + Y A ++ ND+ L++++ P + Sbjct: 60 LIFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGP 119 Query: 137 VQLPQQDQPVPHGTQ-CLAMGWGRVGAH-DPPAQVLQELNVTVVTF-FC----------R 183 LPQ P Q C GWG + + + +LQE V ++ C R Sbjct: 120 GCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIR 179 Query: 184 PHNICTFVPRRKAGICFGDSGGPLICDG------IIQGIDSFVIWGCATRLFPDFFTRVA 237 N+C P K C GDSGGPL+C ++ GI S+ + GCA P +T Sbjct: 180 STNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTW 238 Query: 238 LYVDWIRSTL 247 Y++WI S + Sbjct: 239 SYLNWIASKI 248 >1SC8-U nrPDB Length = 262 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 121/248 (48%), Gaps = 33/248 (13%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGS--HFCGGTLIHPSFVLTAAHCLRDIPQRLVNVV 84 +I+GG ++P+ A++ R GS + CGG+LI P +V++A HC D P++ +V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 85 -LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKL---NDVLLIQLSSP----ANLSASVAT 136 LG + + + F V + L+ + + L ND+ L+++ S A S ++ T Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFC-----RPHN----- 186 + LP GT C G+G+ + D ++L +TVV +PH Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTD--YLYPEQLKMTVVKLISHRECQQPHYYGSEV 192 Query: 187 ----ICTFVPRRKAGICFGDSGGPLICDGIIQG---IDSFVIW--GCATRLFPDFFTRVA 237 +C P+ K C GDSGGPL+C +QG + V W GCA + P +TRV+ Sbjct: 193 TTKMLCAADPQWKTDSCQGDSGGPLVCS--LQGRMTLTGIVSWGRGCALKDKPGVYTRVS 250 Query: 238 LYVDWIRS 245 ++ WIRS Sbjct: 251 HFLPWIRS 258 >5XW8-A nrPDB Length = 133 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 57/135 (42%), Positives = 81/135 (60%), Gaps = 11/135 (8%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +IVGG+ +S PY SL N GSHFCGG+LI+ +V++AAHC + Q V LG Sbjct: 8 KIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSRIQ----VRLG 59 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 HN+ E +Q + A++ + N++ ND++LI+LSSPA L++ VATV LP+ Sbjct: 60 EHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SC 117 Query: 146 VPHGTQCLAMGWGRV 160 GT+CL GWG Sbjct: 118 AAAGTECLISGWGNT 132 >1P57-B nrPDB Length = 255 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 113/254 (44%), Gaps = 31/254 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + P+ SL+ G +H CGG+L+ +VLTAAHC + + L + A Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDG---AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 88 HNVRTQEPTQQHFSV-AQVFLNNY------DAENKLNDVLLIQLSSPANLSASVATVQLP 140 V P V A V+ Y ++E ND+ L+ LSSP L+ + V LP Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 117 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FF---CRPHNICT 189 Q + G C GWG + A VLQE V +++ F+ +P C Sbjct: 118 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 177 Query: 190 FVPRRKAGICFGDSGGPLICDGIIQ--------GIDSFVIWGCATRLFPDFFTRVALYVD 241 P C GDSGGP +C+ I GI S+ GCA P +T+V+ + + Sbjct: 178 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFRE 236 Query: 242 WIRSTLR-RVEAKG 254 WI ++ EA G Sbjct: 237 WIFQAIKTHSEASG 250 >2PSX-A nrPDB Length = 227 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 120/234 (51%), Gaps = 23/234 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G + H++P+ A+L +R P +CG L+HP ++LTAAHC + ++ V LG Sbjct: 1 IINGSDCDMHTQPWQAALLLR--PNQLYCGAVLVHPQWLLTAAHCRK----KVFRVRLGH 54 Query: 88 HNVR-TQEPTQQHFS-VAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 +++ E QQ F V + Y ND++LI+L+ + V + + Sbjct: 55 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 114 Query: 146 VPHGTQCLAMGWGRVGA---HDPPAQVLQELNVTVVT------FFCRPHNICTFVPRRKA 196 GT+CL GWG + H P +VLQ LN++V++ + R + F KA Sbjct: 115 A--GTKCLVSGWGTTKSPQVHFP--KVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKA 170 Query: 197 G--ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 G C GDSGGP++C+G +QG+ S+ + CA P +T + + WI+ T++ Sbjct: 171 GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >3T2N-A nrPDB Length = 372 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 29/253 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + P+ SL+ G+H CGG+L+ +VLTAAHC + + L + A Sbjct: 118 IVGGRDTSLGRWPWQVSLRY---DGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 174 Query: 88 HNVRTQEPTQQHFSV-AQVFLNNY------DAENKLNDVLLIQLSSPANLSASVATVQLP 140 V P V A V+ Y ++E ND+ L+ LSSP L+ + V LP Sbjct: 175 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 234 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FF---CRPHNICT 189 Q + G C GWG + A VLQE V +++ F+ +P C Sbjct: 235 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 294 Query: 190 FVPRRKAGICFGDSGGPLICDGIIQ-----GIDSFVIW--GCATRLFPDFFTRVALYVDW 242 P C GDSGGP +C+ I + V W GCA P +T+V+ + +W Sbjct: 295 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREW 354 Query: 243 IRSTLR-RVEAKG 254 I ++ EA G Sbjct: 355 IFQAIKTHSEASG 367 >1EQ9-A nrPDB Length = 222 Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 78/235 (33%), Positives = 117/235 (49%), Gaps = 26/235 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 IVGG +A PY SL++ GSH CG +++ + VLTAAHC+ + + V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 + + + + V +N NYD NDV L+ L++P + V ++L D+ Sbjct: 58 TNYL---SESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDED 114 Query: 146 VPHGTQCLAMGWG--RVGAHDPPAQVLQELNVTV--------VTFFCRPHNICTFVPRRK 195 + C GWG R+G + P A LQE+ + V + +ICT +R Sbjct: 115 L-ESNPCTLTGWGSTRLGGNTPNA--LQEIELIVHPQKQCERDQWRVIDSHICTLT-KRG 170 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRL-FPDFFTRVALYVDWIRSTLRR 249 G C GDSGGPL+ +G GI SF G L PD +TRV+ +V WI + L++ Sbjct: 171 EGACHGDSGGPLVANGAQIGIVSF---GSPCALGEPDVYTRVSSFVSWINANLKK 222 >6QHB-A nrPDB Length = 223 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 112/230 (48%), Gaps = 18/230 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +V G S PY A+L G+ CGG LIHP +VLTAAHC + Q V LG Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHL---LCGGVLIHPLWVLTAAHCKKPNLQ----VFLGK 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ QE +Q+ SV + ++ +YDA + D++L++L+ PA LS + LP + Sbjct: 54 HNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCS 111 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCR--------PHNICTFVPRRKAGI 198 T C +GWG+ D P + V C + +C + Sbjct: 112 AQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 171 Query: 199 CFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C ++G+ S+ C ++ P +T V Y +WI+ T++ Sbjct: 172 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >3F6U-H nrPDB Length = 240 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 67/217 (30%), Positives = 105/217 (48%), Gaps = 28/217 (12%) Query: 56 CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAEN 114 CG LIHPS+VLTAAHC+ + + LV LG +++R E + + +VF++ NY Sbjct: 27 CGAVLIHPSWVLTAAHCMDESKKLLVR--LGEYDLRRWEKWELDLDIKEVFVHPNYSKST 84 Query: 115 KLNDVLLIQLSSPANLSASVATVQLPQ----QDQPVPHGTQCLAMGWGRVGAHDPPAQVL 170 ND+ L+ L+ PA LS ++ + LP + + G + L GWG + + A+ Sbjct: 85 TDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRN 144 Query: 171 QELNVTVVTFFCRPHNICTFVPRRK-------AGI-------CFGDSGGPLICDGIIQG- 215 + + + PHN C+ V AGI C GDSGGP++ G Sbjct: 145 RTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVAS--FHGT 202 Query: 216 --IDSFVIWGCATRLFPDF--FTRVALYVDWIRSTLR 248 + V WG L ++ +T+V+ Y+DWI +R Sbjct: 203 WFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIR 239 >2AIQ-A nrPDB Length = 231 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 113/234 (48%), Gaps = 27/234 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + ++A + G+ CGGTLI+ +VLTA HC R + + LG Sbjct: 1 VIGGDECNINEHRFLALVYANGS----LCGGTLINQEWVLTARHCDRGN----MRIYLGM 52 Query: 88 HNVRT-QEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 HN++ + + F + F LN + D++LI+L+ P SA +A + LP P Sbjct: 53 HNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSN--P 110 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQEL----NVTVVTF-FCRP-------HNICTFVPR 193 G+ C MGWG + + P L ++ N+ ++ + C+ +C + Sbjct: 111 PSVGSVCRIMGWGTITS---PNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILE 167 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S CA P +T+V Y DWI+S + Sbjct: 168 GGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >4GSO-A nrPDB Length = 232 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 72/235 (30%), Positives = 110/235 (46%), Gaps = 28/235 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + P++A L G +FCG TLI+ +V+TAAHC Q + LG Sbjct: 1 VLGGDECDINEHPFLAFLYSHG----YFCGLTLINQEWVVTAAHCDSTNFQ----MQLGV 52 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N +E D++LI+L P + S +A + LP P Sbjct: 53 HSKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSN--P 110 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQEL----NVTVVTF-FCR--------PHNICTFVP 192 G+ C MGWG + P + ++ N+ +V + C+ +C V Sbjct: 111 PSVGSVCRIMGWGSITI---PNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVL 167 Query: 193 RRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S+ C P +T V Y DWI+ + Sbjct: 168 EGGKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >3BSQ-A nrPDB Length = 227 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 69/232 (29%), Positives = 110/232 (47%), Gaps = 22/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G S P+ +L + GN CGG L++ +VLTAAHC V LG+ Sbjct: 1 IIDGAPCARGSHPWQVAL-LSGN--QLHCGGVLVNERWVLTAAHC----KMNEYTVHLGS 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + + Q ++ F + Y + +ND++L++L+S A LS+ V V+LP + +P Sbjct: 54 DTLGDRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP- 110 Query: 147 PHGTQCLAMGWGRVGAHD---PPAQVLQELNV-------TVVTFFCRPHNICTFVPRRKA 196 GT C GWG + D P + ++ + V +C +P K Sbjct: 111 -PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 169 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C G +QG+ S+ + C P +T+V + WI T++ Sbjct: 170 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1YM0-A nrPDB Length = 238 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 119/244 (48%), Gaps = 33/244 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG EA+P+ P+ S++ R + SHFCGG++I+ +V+ AAHC++ LV++V+G Sbjct: 1 IVGGIEARPYEFPWQVSVR-RKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGE 59 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQ-QDQP 145 H+ +Q V +F+N NYD NDV +I+ + +V + P + Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDY 119 Query: 146 VPHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVVTF--------------FCRPHNIC 188 V +QC GWG + G P LN+T F C N Sbjct: 120 VYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDN-- 175 Query: 189 TFVPRRKAGICFGDSGGPL-ICDG----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWI 243 T + R + C GDSGGPL + DG + GI S+ I GCA+ +P ++RV + WI Sbjct: 176 TGMTDRDS--CQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCASG-YPGVYSRVGFHAGWI 231 Query: 244 RSTL 247 T+ Sbjct: 232 TDTI 235 >1BDA-A nrPDB Length = 265 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 84/257 (32%), Positives = 125/257 (48%), Gaps = 42/257 (16%) Query: 28 IVGGHEAQPHSRPYMASL--QMRGNPGSHF-CGGTLIHPSFVLTAAHCLRD-IPQRLVNV 83 I GG A S P+ A++ + R +PG F CGG LI ++L+AAHC ++ P + V Sbjct: 14 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTV 73 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSP----ANLSASVATVQ 138 +LG +Q F V + ++ +D + ND+ L+QL S A S+ V TV Sbjct: 74 ILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVC 133 Query: 139 LPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFFCRPHNICT---FVPR- 193 LP D +P T+C G+G+ A P ++ L+E +V + P + CT + R Sbjct: 134 LPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLY-----PSSRCTSQHLLNRT 188 Query: 194 -----------RKAG-------ICFGDSGGPLIC--DG--IIQGIDSFVIWGCATRLFPD 231 R G C GDSGGPL+C DG + GI S+ + GC + P Sbjct: 189 VTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL-GCGQKDVPG 247 Query: 232 FFTRVALYVDWIRSTLR 248 +T+V Y+DWIR +R Sbjct: 248 VYTKVTNYLDWIRDNMR 264 >1YC0-A nrPDB Length = 283 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 111/244 (45%), Gaps = 26/244 (10%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR-LVNVVL 85 I+GG + P S P++A++ + G FC G+L+H +V++AAHC P R V+VVL Sbjct: 35 RIIGGSSSLPGSHPWLAAIYI----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 86 GAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLN-DVLLIQLSSPANLSAS----VATVQL 139 G H Q F + + Y N + D++LI+L + A+ V + L Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 150 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAH--DPPAQVLQELNVTVVTFFC----------RPHNI 187 P+ P G +C GWG + + + + + L V C P+ + Sbjct: 151 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 210 Query: 188 CTFVPRRKAGICFGDSGGPLICD-GIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIR 244 C K+ C GDSGGPL C+ + + + W GC P +TRVA YVDWI Sbjct: 211 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 270 Query: 245 STLR 248 +R Sbjct: 271 DRIR 274 >4E7N-A nrPDB Length = 238 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/240 (31%), Positives = 115/240 (47%), Gaps = 32/240 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E + ++ +L + FCGGTLI+ +VLTAAHC R + + LG Sbjct: 1 IIGGDECNINEHRFLVALYT-SRSRTLFCGGTLINQEWVLTAAHCDR----KNFRIKLGM 55 Query: 88 HNVR-------TQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLP 140 H+ + T+ P ++ F ++ NY +K D++LI+L SP S +A LP Sbjct: 56 HSKKVPNEDEQTRVPKEKFFCLSS---KNYTLWDK--DIMLIRLDSPVKNSKHIAPFSLP 110 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVTF-FCR-----------PHNI 187 V G+ C MGWGR+ + V +N+ ++ + CR + Sbjct: 111 SSPPSV--GSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTL 168 Query: 188 CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C + C GDSGGPLIC+G QGI S+ CA P +T+V ++DWI + + Sbjct: 169 CAGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >2R0L-A nrPDB Length = 248 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 111/243 (45%), Gaps = 26/243 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR-LVNVVLG 86 I+GG + P S P++A++ + G FC G+L+H +V++AAHC P R V+VVLG Sbjct: 1 IIGGSSSLPGSHPWLAAIYI----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVF-LNNYDAENKLN-DVLLIQLSSPANLSAS----VATVQLP 140 H Q F + + Y N + D++LI+L + A+ V + LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 141 QQDQPVPHGTQCLAMGWGRVGAH--DPPAQVLQELNVTVVTFFC----------RPHNIC 188 + P G +C GWG + + + + + L V C P+ +C Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 189 TFVPRRKAGICFGDSGGPLICD-GIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRS 245 K+ C GDSGGPL C+ + + + W GC P +TRVA YVDWI Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 246 TLR 248 +R Sbjct: 237 RIR 239 >2F91-A nrPDB Length = 237 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/238 (30%), Positives = 113/238 (47%), Gaps = 24/238 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGS-HFCGGTLIHPSFVLTAAHCL----RDIPQRLVN 82 IVGG +A PY S Q S HFCG ++ + ++ +TA HC+ + P L Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGL-Q 59 Query: 83 VVLGAHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQ 141 +V G ++ E ++Q +V+++ L N+D ND+ L++LS + +VA + LP+ Sbjct: 60 IVAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPE 119 Query: 142 QDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHN---------ICTFV 191 Q + GWG VLQ++ V +V+ CR IC V Sbjct: 120 QGHTATG--DVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGV 177 Query: 192 PRRKAGICFGDSGGPLICDGI----IQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 P C GDSGGPL + GI S+ +GCA +P +T V+ +VDWI++ Sbjct: 178 PEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSYHVDWIKA 234 >1X7A-C nrPDB Length = 235 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/241 (29%), Positives = 119/241 (49%), Gaps = 28/241 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A+P P+ L + + FCGG++I+ +V+TAAHC+ P + VV G Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDA---FCGGSIINEKWVVTAAHCIE--PGVKITVVAGE 55 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAE-NKLN-DVLLIQLSSPANLSASVATVQLPQQDQ 144 +N EPT+Q +V + ++Y+A NK + D+ L++L P L++ V + + ++ Sbjct: 56 YNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 145 P---VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---------TFFCRPHNICTFVP 192 + G+ ++ GWGRV A +LQ L V +V F + C Sbjct: 116 TNIFLKFGSGYVS-GWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFH 174 Query: 193 RRKAGICFGDSGGPLICDGIIQG---IDSFVIWG--CATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP + + ++G + + WG CA + +T+V+ YV+WI+ Sbjct: 175 EGGKDSCQGDSGGPHVTE--VEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKT 232 Query: 248 R 248 + Sbjct: 233 K 233 >3LC3-A nrPDB Length = 235 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 72/241 (29%), Positives = 124/241 (51%), Gaps = 28/241 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG +A+P P+ L + + FCGG++++ +++TAAHC+ + + VV G Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDA---FCGGSIVNEKWIVTAAHCVETGVK--ITVVAGE 55 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAE-NKLN-DVLLIQLSSPANLSASVATVQLPQQDQ 144 HN+ E T+Q +V ++ +NY+A NK N D+ L++L P L++ V + + ++ Sbjct: 56 HNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 145 P---VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV--------TFFCRPHNI-CTFVP 192 + G+ ++ GWGRV A VLQ L V +V T F +N+ C Sbjct: 116 TNIFLKFGSGYVS-GWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFH 174 Query: 193 RRKAGICFGDSGGPLICDGIIQG---IDSFVIWG--CATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP + + ++G + + WG CA + +T+V+ YV+WI+ Sbjct: 175 EGGRDSCQGDSGGPHVTE--VEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKT 232 Query: 248 R 248 + Sbjct: 233 K 233 >1SI5-H nrPDB Length = 240 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 23/222 (10%) Query: 41 YMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNV--RTQEPTQQ 98 +M SL+ R H CGG+LI S+VLTA C + LG H+V R E +Q Sbjct: 13 WMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQ 69 Query: 99 HFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWG 158 +V+Q+ Y E +D++L++L+ PA L V+T+ LP +P T C GWG Sbjct: 70 VLNVSQLV---YGPEG--SDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWG 124 Query: 159 RVGAHDPPAQVLQELNVTVVTFFCRPHN----------ICTFVPRRKAGICFGDSGGPLI 208 G + + + C H+ IC + +G C GD GGPL+ Sbjct: 125 YTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLV 184 Query: 209 CDGIIQGIDSFVI---WGCATRLFPDFFTRVALYVDWIRSTL 247 C+ + VI GCA P F RVA Y WI + Sbjct: 185 CEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >2ASU-B nrPDB Length = 234 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 79/242 (32%), Positives = 113/242 (46%), Gaps = 37/242 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD--IPQRLVNVVL 85 +VGGH P + P+ SL+ R G HFCGG+L+ ++LTA C +P V L Sbjct: 1 VVGGH---PGNSPWTVSLRNR--QGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 86 GA--HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G N + EP+ Q VA++ ++ ++L++L L+ VA + LP + Sbjct: 56 GTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ-----LVLLKLERSVTLNQRVALICLPPEW 110 Query: 144 QPVPHGTQCLAMGWGRV-GAHDPPAQVLQELNVTVVTFFC--------RPHNICTFVPRR 194 VP GT+C GWG G + + LNV + C R +CT Sbjct: 111 YVVPPGTKCEIAGWGETKGTGNDTVLNVALLNV-ISNQECNIKHRGRVRESEMCTEGLLA 169 Query: 195 KAGICFGDSGGPLIC--------DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 G C GD GGPL C +GII I + V CA +P FTRV+++VDWI Sbjct: 170 PVGACEGDYGGPLACFTHNSWVLEGII--IPNRV---CARSRWPAVFTRVSVFVDWIHKV 224 Query: 247 LR 248 +R Sbjct: 225 MR 226 >3DFJ-A nrPDB Length = 263 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 107/252 (42%), Gaps = 35/252 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVVLG 86 I GG A P+ S+ G H CGG+L+ +VL+AAHC + + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH + + + ++ + + +Y E D+ L+QLS P S + + LP + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQV-----LQELNVTVVT-----------------FFCR 183 P+G C GWG V P + LQ+L V +++ F + Sbjct: 118 FPNGLHCTVTGWGHVA---PSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQ 174 Query: 184 PHNICTFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWG--CATRLFPDFFTRVALY 239 +C C GDSGGPL C +G+ + V WG C R P +T + Y Sbjct: 175 EDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY-LTGIVSWGDACGARNRPGVYTLASSY 233 Query: 240 VDWIRSTLRRVE 251 WI+S + ++ Sbjct: 234 ASWIQSKVTELQ 245 >4DGJ-A nrPDB Length = 235 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/238 (26%), Positives = 110/238 (46%), Gaps = 22/238 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL--RDIPQRLVNVVL 85 IVGG +A+ + P++ L CG +L+ ++++AAHC+ R++ +L Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDR---LLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 86 GAH-NVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H P + ++ +N +Y+ K ND+ ++ L N + + + LP+++ Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPR 193 Q P G C GWG V A +LQE +V +++ + + IC Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEE 177 Query: 194 RKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL+C + G+ SF + CA P + RV+ + +WI+S L Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFTEWIQSFL 234 >3E0N-B nrPDB Length = 271 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 69/254 (27%), Positives = 107/254 (42%), Gaps = 29/254 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVVLG 86 I GG A P+ S+ G H CGG+L+ +VL+AAHC + + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH + + + ++ + + +Y E D+ L+QLS P S + + LP Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 146 VPHGTQCLAMGWGRVGAHDP--PAQVLQELNVTVVT-----------------FFCRPHN 186 P+G C GWG V + LQ+L V +++ F + Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 187 ICTFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWG--CATRLFPDFFTRVALYVDW 242 +C C GDSGGPL C +G+ + V WG C R P +T + Y W Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWY-LTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 243 IRSTLRRVEAKGRP 256 I+S + ++ + P Sbjct: 237 IQSKVTELQPRVVP 250 >1EKB-B nrPDB Length = 235 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 64/238 (26%), Positives = 112/238 (47%), Gaps = 22/238 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL--RDIPQRLVNVVL 85 IVGG +++ + P++ +L CG +L+ ++++AAHC+ R++ VL Sbjct: 1 IVGGSDSREGAWPWVVALYFDD---QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 86 GAHNVRT-QEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H P + + Q+ +N +Y+ K ND+ ++ L N + + + LP+++ Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPR 193 Q P G C GWG + A VLQE +V +++ + + +C Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 194 RKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL+C ++ G+ SF + CA P + RV + +WI+S L Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFTEWIQSFL 234 >3VGC-B nrPDB Length = 131 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 52/135 (38%), Positives = 75/135 (55%), Gaps = 12/135 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC---LRDIPQRLVNVV 84 IV G EA P S P+ SLQ + G HFCGG+LI+ ++V+TAAHC D+ VV Sbjct: 1 IVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHCGVTTSDV------VV 52 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G + + Q +A+VF N+ Y++ ND+ L++LS+ A+ S +V+ V LP Sbjct: 53 AGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSAS 112 Query: 144 QPVPHGTQCLAMGWG 158 GT C+ GWG Sbjct: 113 DDFAAGTTCVTTGWG 127 >1OP0-A nrPDB Length = 234 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 68/236 (28%), Positives = 108/236 (45%), Gaps = 28/236 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG+E + ++ + N FCGGTLI+P +V+TAAHC Q + LG Sbjct: 1 VIGGNECDINEHRFLVAFF---NTTGFFCGGTLINPEWVVTAAHCDSTDFQ----MQLGV 53 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N + E D++LI+L P + S +A + LP Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPS 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQEL----NVTVV----------TFFCRPHNICTFV 191 V G+ C MGWG + P + ++ N+ ++ +C + Sbjct: 114 V--GSVCRIMGWGSI---TPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGI 168 Query: 192 PRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + C GDSGGPLIC+G QGI S+ C P +T V Y DWI+ + Sbjct: 169 VQGGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >2JET-B nrPDB Length = 128 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 52/134 (38%), Positives = 72/134 (53%), Gaps = 12/134 (8%) Query: 31 GHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC---LRDIPQRLVNVVLGA 87 G +A P S P+ SLQ + G HFCGG+LI +V+TAAHC D+ VV G Sbjct: 1 GEDAIPGSWPWQVSLQDK--TGFHFCGGSLISEDWVVTAAHCGVKTSDV------VVAGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + + E Q +AQVF N ++ ND+ L++L++PA S +V+ V LP D Sbjct: 53 FDQGSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDF 112 Query: 147 PHGTQCLAMGWGRV 160 P GT C GWG+ Sbjct: 113 PPGTVCATTGWGKT 126 >2F83-A nrPDB Length = 625 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 67/231 (29%), Positives = 97/231 (41%), Gaps = 15/231 (6%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 IVGG + P+ +L H CGG++I ++LTAAHC + +++ V G Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 447 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 N + F V ++ +++ Y D+ L++L + N + S + LP + Sbjct: 448 ILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDR 507 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFC----RPHN-----ICTFVPRRK 195 T C GWG D LQ+ + +VT C R H IC Sbjct: 508 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 567 Query: 196 AGICFGDSGGPLICD-GIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWI 243 C GDSGGPL C + + W GCA R P +T V YVDWI Sbjct: 568 KDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >1A5I-A nrPDB Length = 265 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 77/251 (30%), Positives = 122/251 (48%), Gaps = 34/251 (13%) Query: 29 VGGHEAQPHSRPYMASL--QMRGNPGSHF-CGGTLIHPSFVLTAAHCLRD--IPQRLVNV 83 GG S P+ A++ Q R + G F CGG LI +VLTAAHC ++ +P +L V Sbjct: 15 TGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVV 74 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSP----ANLSASVATVQ 138 + + V+ E +Q F V + ++ +D + ND+ L+QL S A S SV + Sbjct: 75 LGRTYRVKPGEE-EQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAIC 133 Query: 139 LPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVV-TFFCRP---------HNI 187 LP+ + +P T+C G+G+ + P ++ L+E +V + + C P +N+ Sbjct: 134 LPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNM 193 Query: 188 CTFVPRRKAGI-------CFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRV 236 R I C GDSGGPL+C + GI S+ + GC + P +T+V Sbjct: 194 LCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKV 252 Query: 237 ALYVDWIRSTL 247 Y+ WIR + Sbjct: 253 TNYLGWIRDNM 263 >4XDE-A nrPDB Length = 257 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 107/244 (43%), Gaps = 31/244 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 +VGG A + PY+A+L G FC G+LI P +VLTAAHCL+D P + VVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 87 AHNVR-TQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPAN-----LSASVATVQLP 140 + EP Q + + + +D+ L++L A+ LS V V LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 141 QQDQPVPHGTQCLAMGWG-RVGAHDPPAQVLQELNVTVVTFF-CR----------PHNIC 188 T C GWG + + A LQE V ++ C P +C Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLC 178 Query: 189 TFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C GDSGGPL+C+ +QGI S+ GC R P +T VA Y+ Sbjct: 179 AGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVYTDVAYYLA 237 Query: 242 WIRS 245 WIR Sbjct: 238 WIRE 241 >1M9U-A nrPDB Length = 241 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 67/237 (28%), Positives = 108/237 (45%), Gaps = 21/237 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG A P P+ S Q + SH CG +L+ + L+A+HC+ + + V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDA--ENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 TQ + NY A + ND+ ++ L++ +L ++ LP + Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-CRP------------HNICTFVP 192 GT C+ GWGR + +LQ+ ++ V+T C ++IC P Sbjct: 121 DYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQDP 180 Query: 193 RRKAGICFGDSGGPLIC-DGIIQ--GIDSFVIWGCATRLFPDF---FTRVALYVDWI 243 G C GDSGGPL C DG + G+ S+V+ PD+ +TRV+ Y+ WI Sbjct: 181 AGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 >6AOD-C nrPDB Length = 245 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 19/233 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 IVGG + P+ +L H CGG++I ++LTAAHC + +++ V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQ-DQ 144 + F V ++ +++ Y D+ L++L + + S + LP + D+ Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-----FFCRPHN-----ICTFVPRR 194 V + T C GWG D LQ+ + +VT R H IC Sbjct: 121 NVIY-TDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 195 KAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWI 243 C GD+GGPL C + GI S+ GCA R P +T V YVDWI Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 231 >2XXL-A nrPDB Length = 408 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/260 (26%), Positives = 107/260 (41%), Gaps = 46/260 (17%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHF-CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 + G+E + SRP+MA L+ + S F CGG +I ++LTAAHC+ + L + LG Sbjct: 119 VSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRLG 178 Query: 87 AHNVRTQEPTQQHFSVAQ-------------VFLNNYDAENKLNDVLLIQLSSPANLSAS 133 H + T+E +Q + + YDA + ++D+ L++L+ Sbjct: 179 EHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQKH 238 Query: 134 VATVQLPQQDQPVPHGTQC---LAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTF 190 + + LP D+ Q GWG + + VL + NV + +P + C+ Sbjct: 239 IKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPL-----QPRSACSQ 292 Query: 191 VPRRKAGI-------------CFGDSGGPLICDG----------IIQGIDSFVIWGCATR 227 RR + C GDSGGPL + GI S + C Sbjct: 293 AYRRAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQI 352 Query: 228 LFPDFFTRVALYVDWIRSTL 247 P +T V YV WI T+ Sbjct: 353 SLPGLYTNVGEYVQWITDTM 372 >1BQY-A nrPDB Length = 234 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 112/239 (46%), Gaps = 34/239 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 + GG E + SL + N CGGTLI+ +V+TAAHC + Q L G Sbjct: 1 VFGGDECNINEH---RSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLL----FGV 53 Query: 88 HNVRT-QEPTQQHFSVAQVFLNNYDAENKLN-DVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + E Q + F N +++++ D++LI+L S + S +A + LP Sbjct: 54 HSKKILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPS 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQEL----NVTVVTF-FCRP---------HNICTFV 191 V G+ C MGWG+ P ++ ++ N+ ++ CR +C + Sbjct: 114 V--GSVCRIMGWGKT---IPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGI 168 Query: 192 PRRKAGICFGDSGGPLICDGIIQGIDSFVIWG---CATRLFPDFFTRVALYVDWIRSTL 247 + C DSGGPLIC+GI QGI V WG C P +T+V Y+DWI+S + Sbjct: 169 LQGGRDTCHFDSGGPLICNGIFQGI---VSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >3P8G-A nrPDB Length = 241 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 105/246 (42%), Gaps = 35/246 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI-------PQRL 80 +VGG +A P+ SL G H CG +LI P+++++AAHC D P + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQ--GHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 81 VNVVLGAHNVRTQE-PTQQHFSVAQV----FLNNYDAENKLNDVLLIQLSSPANLSASVA 135 LG H+ + P Q + ++ F N++ + D+ L++L PA S+ V Sbjct: 59 -TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDY---DIALLELEKPAEYSSMVR 114 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR--------PHN 186 + LP P G GWG A +LQ+ + V+ C P Sbjct: 115 PICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRM 174 Query: 187 ICTFVPRRKAGICFGDSGGPLI---CDG-IIQGIDSFVIW--GCATRLFPDFFTRVALYV 240 +C C GDSGGPL DG I Q V W GCA R P +TR+ L+ Sbjct: 175 MCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQA--GVVSWGDGCAQRNKPGVYTRLPLFR 232 Query: 241 DWIRST 246 DWI+ Sbjct: 233 DWIKEN 238 >3S69-A nrPDB Length = 234 Score = 83.6 bits (205), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 101/233 (43%), Gaps = 22/233 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + SL N FC GTLI+ +VLTAAHC Q + LG Sbjct: 1 VIGGDECNINEH---RSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQ----MKLGV 53 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N + E D++LI+L S + S + + LP Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPS 113 Query: 146 VPHGTQCLAMGWG-----RVGAHDPPAQVLQELNVTVV------TFFCRPHNICTFVPRR 194 V G+ C MGWG +V D P L V +C + Sbjct: 114 V--GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEG 171 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI SF C L P +T+V Y WI+S + Sbjct: 172 GKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >4LK4-A nrPDB Length = 357 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 65/245 (26%), Positives = 113/245 (46%), Gaps = 23/245 (9%) Query: 18 LLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPG--SHFCGGTLIHPSFVLTAAHCLRD 75 + S A ++ I+ G A P + +L RG FCGG+ + +VLTAAHC Sbjct: 1 MESTADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDS 60 Query: 76 IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASV 134 V+V++GA+++ ++ + +++ + +Y N LND+ +++L+ ++L A Sbjct: 61 RSAASVDVIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPA-- 117 Query: 135 ATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPP--AQVLQELNVTVVT-FFCR-------- 183 T+ P +P T GWG PP +LQE++V +V+ C+ Sbjct: 118 ITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGIS 177 Query: 184 --PHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWG---CATRLFPDFFTRVAL 238 P++ R C GD+GGP++ + + V WG CA +T V+ Sbjct: 178 SDPNSTNFCAARLTKDSCQGDAGGPIVVKTGREQL-GIVSWGDEQCAKTGTYGVYTNVSY 236 Query: 239 YVDWI 243 + DWI Sbjct: 237 FRDWI 241 >2OLG-A nrPDB Length = 278 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 74/269 (27%), Positives = 117/269 (43%), Gaps = 54/269 (20%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHF----CGGTLIHPSFVLTAAHCLRDIPQR 79 A +I+ G + P P+ A + + + S+F CGG+LI+ +++TAAHC+ R Sbjct: 19 EADKILNGDDTVPEEFPWTAMIGYKNS--SNFEQFACGGSLINNRYIVTAAHCVAGRVLR 76 Query: 80 LV----NVVLGAHNVRTQ--------------------EPTQQHFSVAQVFLNNYDAENK 115 +V V LG N T E T QH ++++ Sbjct: 77 VVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVD------GSKDR 130 Query: 116 LNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNV 175 +D+ LI+L+ + + V LPQ ++ V G + +GWGR + + Q+L V Sbjct: 131 YHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAV 189 Query: 176 TVV-------TFFC-----RPHNICTFVPRRKAGICFGDSGGPLICDGIIQG--IDSFVI 221 VV TF R +C + K C GDSGGPL+ + Q ++ V Sbjct: 190 PVVHAEQCAKTFGAAGVRVRSSQLCAGGEKAKDS-CGGDSGGPLLAERANQQFFLEGLVS 248 Query: 222 WG--CATRLFPDFFTRVALYVDWIRSTLR 248 +G C T +P +T+V Y DWI +R Sbjct: 249 FGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >3H7O-A nrPDB Length = 228 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 59/229 (25%), Positives = 104/229 (45%), Gaps = 12/229 (5%) Query: 30 GGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHN 89 GG + P+ +++ S CGG ++ FVLTAAHC+ D + + + N Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 90 VRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVAT-VQLPQQDQPVPH 148 + ++P + V+ V+L+ Y E ND+ +++LS P L + +LP + Sbjct: 62 LW-EDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 149 GTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRPHNICTFVP-----RRKAGICF-- 200 G+ L G+G DP L+ +TVV CR F+ +K G+ Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLES 180 Query: 201 GDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GD+G P + + G+ ++ + P+ FT+V YV WI+ +++ Sbjct: 181 GDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >2B9L-A nrPDB Length = 394 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 117/258 (45%), Gaps = 41/258 (15%) Query: 32 HEAQPHSRPYM-ASLQMRGNPGSH----FCGGTLIHPSFVLTAAHCLRDIPQRL--VNVV 84 +EA+ P+M A L+ PGS CGG+LI PS VLT AHC+ L + + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 85 LGAHNVRTQEPT--QQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQ 141 G + T++ Q + QV + +N++ + +NDV L+ L P + ++ T+ LPQ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 142 QDQPVPHGTQCLAMGWGR--VGAHDPPAQVLQELNVTVV----------------TFFCR 183 Q Q + T+C A GWG+ G+ + +L+++ + V F Sbjct: 255 QSQ-IFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 184 PHNICTFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFPDFFTRV 236 +C + K C GD G PL C + GI ++ I GC P + V Sbjct: 314 QTFVCAGGEQGKD-TCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI-GCGDENVPGVYANV 371 Query: 237 ALYVDWIRSTLRRVEAKG 254 A + +WI + ++AKG Sbjct: 372 AHFRNWID---QEMQAKG 386 >2PKA-B nrPDB Length = 152 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 47/152 (30%), Positives = 78/152 (51%), Gaps = 16/152 (10%) Query: 111 DAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVL 170 D ++ +D++L++L SPA ++ +V ++LP Q+ + G+ C A GWG + + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 171 QELNVTVVTF----FC---RPHNICT------FVPRRKAGICFGDSGGPLICDGIIQGID 217 E+ +T FC P + ++P K C GDSGGPLIC+G+ QGI Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKD-TCMGDSGGPLICNGMWQGIT 118 Query: 218 SFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 S+ C + P +T++ Y+DWI T+ Sbjct: 119 SWGHTPCGSANKPSIYTKLIFYLDWIDDTITE 150 >1C5M-D nrPDB Length = 255 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/240 (27%), Positives = 104/240 (43%), Gaps = 26/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + P+ A L N G FCGGT++ ++LTAAHCL + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEG--FCGGTILSEFYILTAAHCL--YQAKRFKVRVGD 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQD--- 143 N +E + V V +N + E D+ +++L +P +VA LP++D Sbjct: 57 RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAE 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---------TFFCRPHNICTFVPRR 194 + + G+GR + L+ L V V +F + C + Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTK 176 Query: 195 KAGICFGDSGGPLIC----DGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTLR 248 + C GDSGGP + + GI V W GCA + +T+V ++ WI +++ Sbjct: 177 QEDACQGDSGGPHVTRFKDTYFVTGI---VSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >5KWM-A nrPDB Length = 230 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/225 (29%), Positives = 94/225 (41%), Gaps = 20/225 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG +A P+ +L G FCGGTL P+ V+TAAHC +NVV G Sbjct: 1 IVGGEDANVQDHPFTVALVTP--DGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGR 58 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP-- 145 + + E T + V DA DV ++ L +P A ++L + D Sbjct: 59 TVMSSNEGTVSKVTNVWVHPEYQDAAKGF-DVSVLTLEAPVKE----APIELAKADDAGY 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRRKA 196 P T +GWG A LQ+ V V + + +C VP Sbjct: 114 APD-TAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGV 172 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C GDSGGP++ + + G+ S+ GCA P + RV Y D Sbjct: 173 DTCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYD 216 >5LPF-A nrPDB Length = 234 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/228 (28%), Positives = 101/228 (44%), Gaps = 26/228 (11%) Query: 38 SRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC-LRDIPQRLVN---VVLGAHNVRTQ 93 S+P+ SL N S C G L+ S+VLTAAHC + + R+ + ++L +R Sbjct: 14 SQPWQVSL---FNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRT 70 Query: 94 EPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQ-DQPVPHGTQC 152 + H Q +D++L++L+ P L V +QLP + QP G QC Sbjct: 71 TRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP---GDQC 127 Query: 153 LAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVP------------RRKAGICF 200 GWG A + + L + +T P F P R C Sbjct: 128 QVAGWGTTAARR--VKYNKGLTCSSITIL-SPKECEVFYPGVVTNNMICAGLDRGQDPCQ 184 Query: 201 GDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 DSGGPL+CD +QGI S+ ++ C + P +T++ Y+ WI +R Sbjct: 185 SDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 232 >2OQ5-A nrPDB Length = 232 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 70/236 (29%), Positives = 101/236 (42%), Gaps = 26/236 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI--PQRLVNVVL 85 IVGG E + P+ ASLQ G SH CG TLI+ +++++AAHC P R Sbjct: 1 IVGGTEVEEGEWPWQASLQWDG---SHRCGATLINATWLVSAAHCFTTYKNPARWT---- 53 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 A T +P++ + ++ ++ Y + D+ L +LSSP + +V V LP Sbjct: 54 -ASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY 112 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR----------PHNICTFVPR 193 G G+G + L++ VT++ C P +C Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLE 172 Query: 194 RKAGICFGDSGGPLICDGI--IQGIDSFVIWG--CATRLFPDFFTRVALYVDWIRS 245 K C GDSGGPL+ I + V WG CA P +TRV DWI S Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 228 >4Z6A-H nrPDB Length = 249 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 70/239 (29%), Positives = 109/239 (45%), Gaps = 22/239 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 IVGG P+ L + G + CGGTLI+ +V++AAHC I R + VLG Sbjct: 1 IVGGKVCPKGECPWQVLLLVNG---AQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQ--- 142 H++ + +Q VAQV + + Y +D+ L++L P L+ V + LP++ Sbjct: 58 EHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFS 117 Query: 143 DQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNV-TVVTFFCR--------PHNICTFVPR 193 ++ + L GWG++ A L LNV ++T C + C Sbjct: 118 ERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSD 177 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP + GI S+ GCAT +TRV+ Y++W++ +R Sbjct: 178 GSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQYIEWLQKLMR 235 >4IGD-A nrPDB Length = 406 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 71/257 (27%), Positives = 110/257 (42%), Gaps = 49/257 (19%) Query: 26 AEIVGGHEAQPHSRPYMASL-QMRGNPGSHFCGGTLIHPSFVLTAAHC-----------L 73 A+I G AQ + P++A L + G P FCGG+L+ S+++TAAHC L Sbjct: 154 AQIFNGRPAQKGTTPWIAMLSHLNGQP---FCGGSLLGSSWIVTAAHCLHQSLDPEDPTL 210 Query: 74 RD---IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPAN 129 RD + ++LG H + +QH V L+ YD NDV L++L Sbjct: 211 RDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPV 270 Query: 130 LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNIC- 188 L+A V + LP+ P G + GWG+ P + L E+ + +V H+ C Sbjct: 271 LNAFVMPICLPE--GPQQEGAMVIVSGWGKQFLQRFP-ETLMEIEIPIVD-----HSTCQ 322 Query: 189 -TFVPRRK---------------AGICFGDSGGPLICDGIIQG---IDSFVIWG--CATR 227 + P +K C GDSGGP++ +G + V WG C + Sbjct: 323 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKK 382 Query: 228 LFPDFFTRVALYVDWIR 244 ++ + DWI+ Sbjct: 383 DRYGVYSYIHHNKDWIQ 399 >1KIG-H nrPDB Length = 241 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 103/240 (42%), Gaps = 26/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + P+ A L N G FCGGT+++ +VLTAAHCL + V V G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG--FCGGTILNEFYVLTAAHCLHQAKRFTVRV--GD 56 Query: 88 HNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD--- 143 N +E + V V + + E D+ +++L +P +VA LP++D Sbjct: 57 RNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAE 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---------TFFCRPHNICTFVPRR 194 + + G+GR + L+ L V V +F P+ C + Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQ 176 Query: 195 KAGICFGDSGGPLIC----DGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP + + GI V W GCA + +T+V+ ++ WI ++ Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGI---VSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >4DJZ-B nrPDB Length = 251 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 108/255 (42%), Gaps = 49/255 (19%) Query: 28 IVGGHEAQPHSRPYMASL-QMRGNPGSHFCGGTLIHPSFVLTAAHC-----------LRD 75 I G AQ + P++A L + G P FCGG+L+ S+++TAAHC LRD Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQP---FCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 76 ---IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131 + ++LG H + +QH V L+ YD NDV L++L L+ Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 117 Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNIC--T 189 A V + LP+ P G + GWG+ P + L E+ + +V H+ C Sbjct: 118 AFVMPICLPE--GPQQEGAMVIVSGWGKQFLQRFP-ETLMEIEIPIVD-----HSTCQKA 169 Query: 190 FVPRRK---------------AGICFGDSGGPLICDGIIQG---IDSFVIWG--CATRLF 229 + P +K C GDSGGP++ +G + V WG C + Sbjct: 170 YAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDR 229 Query: 230 PDFFTRVALYVDWIR 244 ++ + DWI+ Sbjct: 230 YGVYSYIHHNKDWIQ 244 >4IW4-E nrPDB Length = 279 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 70/267 (26%), Positives = 110/267 (41%), Gaps = 48/267 (17%) Query: 28 IVGGHEAQPHSRPYMASLQMRGN---PGSHFCG-GTLIHPSFVLTAAHCLRD-------- 75 I+GG A+P P+ A + + P + G G L+ S++LTAAH LR Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 76 -IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASV 134 + + V V LG H+VR + + V +++ +N +D+ L+QL P L V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 135 ATVQLP--QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV------VTFFCRPHN 186 V LP + + P PH L GWG + +++ T+ V PH Sbjct: 121 MPVCLPRLEPEGPAPH-MLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 187 ICTFVPRRKAG-------------------ICFGDSGGP-LICDGIIQG--IDSFVIWG- 223 C ++G C GDSGG +I D + Q + V WG Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 224 ---CATRLFPDFFTRVALYVDWIRSTL 247 C ++ +T+V+ YVDW+ + Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >2XRC-A nrPDB Length = 565 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 94/243 (38%), Gaps = 32/243 (13%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QR 79 R IVGG AQ P+ +++ + CGG I ++LTAAHCLR Q Sbjct: 318 RRKRIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQI 374 Query: 80 LVNVVLGAHNVRTQEPTQQHFSVAQV----FLNNYDAENKLNDVLLIQLSSPANLSASVA 135 VV H P + + V F NY+A ND+ LI++ N Sbjct: 375 WTTVVDWIH------PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCEL 428 Query: 136 TVQLPQQDQPVPHGTQ----CLAMGWGRVGAHD-------PPAQVLQELNVTVVTFFCRP 184 +P P+ Q C+ GWGR ++ +++ + F Sbjct: 429 PRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEK 488 Query: 185 HNICTFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWG--CATRLFPDFFTRVALYV 240 C C GDSGGPL+C + + V WG C FP +T+VA Y Sbjct: 489 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 548 Query: 241 DWI 243 DWI Sbjct: 549 DWI 551 >5O32-I nrPDB Length = 244 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/245 (27%), Positives = 95/245 (38%), Gaps = 32/245 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRLVNV 83 IVGG AQ P+ +++ + CGG I ++LTAAHCLR Q V Sbjct: 1 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 57 Query: 84 VLGAHNVRTQEPTQQHFSVAQV----FLNNYDAENKLNDVLLIQLSSPANLSASVATVQL 139 V H P + + V F NY+A ND+ LI++ N + Sbjct: 58 VDWIH------PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI 111 Query: 140 PQQDQPVPHGTQ----CLAMGWGRVGAHD-------PPAQVLQELNVTVVTFFCRPHNIC 188 P P+ Q C+ GWGR ++ +++ + F C Sbjct: 112 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMEC 171 Query: 189 TFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWG--CATRLFPDFFTRVALYVDWIR 244 C GDSGGPL+C + + V WG C FP +T+VA Y DWI Sbjct: 172 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 231 Query: 245 STLRR 249 + R Sbjct: 232 YHVGR 236 >4KKD-A nrPDB Length = 433 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 69/263 (26%), Positives = 109/263 (41%), Gaps = 48/263 (18%) Query: 28 IVGGHEAQPHSRPYMASLQMRGN---PGSHFCG-GTLIHPSFVLTAAHCLRD-------- 75 I+GG A+P P+ A + + P + G G L+ S++LTAAH LR Sbjct: 155 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 214 Query: 76 -IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASV 134 + + V V LG H+VR + + V +++ +N +D+ L+QL P L V Sbjct: 215 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 274 Query: 135 ATVQLP--QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV------VTFFCRPHN 186 V LP + + P PH +A GWG + +++ T+ V PH Sbjct: 275 MPVCLPRLEPEGPAPHMLGLVA-GWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 187 ICTFVPRRKAG-------------------ICFGDSGGP-LICDGIIQG--IDSFVIWG- 223 C ++G C GDSG +I D + Q + V WG Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWGG 393 Query: 224 ---CATRLFPDFFTRVALYVDWI 243 C ++ +T+V+ YVDW+ Sbjct: 394 PEECGSKQVYGVYTKVSNYVDWV 416 >1PQ7-A nrPDB Length = 224 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 18/192 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A P++ S+ G P +CGG+L++ + VLTAAHC+ Q + G+ Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGP---WCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGS 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 + RT S +V +Y N ND+ +++LS+ ++ +L Sbjct: 58 LS-RTSGGITSSLSSVRVHP-SYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPV 113 Query: 148 HGTQCLAMGWGRV--GAHDPPAQVLQELNVTVVTFFCRPHN---------ICTFVPRRKA 196 G+ GWG G P +L+ V CR C V Sbjct: 114 AGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGK 173 Query: 197 GICFGDSGGPLI 208 C GDSGGP++ Sbjct: 174 DSCQGDSGGPIV 185 >4BXW-A nrPDB Length = 423 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 66/254 (25%), Positives = 112/254 (44%), Gaps = 44/254 (17%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IV G + + P+ A+L FCGGT++ P +VLTAAHC+ + ++VV+G Sbjct: 170 IVNGMDCKLGECPWQAALVDEKE--GVFCGGTILSPIYVLTAAHCINET--ETISVVVGE 225 Query: 88 HNVRTQEPTQQHFSVAQVFLN----------NYDAENKLNDVLLIQLSSPANLSASVATV 137 + +++ T SV +++++ +D D+ +IQ+ +P S +V Sbjct: 226 ID-KSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPA 284 Query: 138 QLPQQD---QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---------------T 179 LP D Q + + G+GR+ P ++ L+ L V V Sbjct: 285 CLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPN 344 Query: 180 FFCRPHNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTR 235 FC ++ +PR C GDSGGP I GI S GCA +T+ Sbjct: 345 MFCAGYDT---LPR---DACQGDSGGPHTTVYRDTHFITGIVS-SGEGCARNGKYGNYTK 397 Query: 236 VALYVDWIRSTLRR 249 ++ ++ WI+ +R+ Sbjct: 398 LSKFIPWIKRIMRQ 411 >5UBM-A nrPDB Length = 252 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 103/261 (39%), Gaps = 56/261 (21%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG +A + P+ NP + GG LI+ +VLTAAH + R + +G+ Sbjct: 2 IIGGSDADIKNFPWQVFFD---NP---WAGGALINEYWVLTAAHVVEG--NREPTMYVGS 53 Query: 88 HNVRTQE-PTQQHFSVAQVFL-------------NNYDAENKLNDVLLIQLSSPANLSAS 133 +V+T + + VF+ N+D ND+ L++L P + + Sbjct: 54 TSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFD-----NDIALVRLKDPVKMGPT 108 Query: 134 VATVQLP--QQDQPVPHGTQCLAMGWGRVGAHD------------PPAQVLQELNVTVVT 179 V+ + LP D + G L GWGR D P + +E+ V T Sbjct: 109 VSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPT 168 Query: 180 -----FFCRPHNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWG--CATRL 228 + P+ IC + C GDSGG D V WG C T Sbjct: 169 ADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY- 226 Query: 229 FPDFFTRVALYVDWIRSTLRR 249 +TRV YVDWI T++ Sbjct: 227 --GLYTRVKNYVDWIMKTMQE 245 >2HLC-A nrPDB Length = 230 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 102/232 (43%), Gaps = 24/232 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSH-FCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+ G+EA PY A L + +CGG+LI ++LTAAHC+ D V+VV+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHD----AVSVVVY 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + E S + + ++ + LNDV LI++ + ++ ++LP ++ Sbjct: 57 LGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELN 115 Query: 147 PHGTQCLAM--GWGRVGAHDPPAQVLQ-ELNVTVVTFFCRPH---------NICTFVPRR 194 A GWG+ + +LQ N+ + C IC Sbjct: 116 NKFENIWATVSGWGQ---SNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDG 172 Query: 195 KAGICFGDSGGPLICD--GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 K+ CFGDSGGP + ++ G+ SFV P F+RV Y+DWI+ Sbjct: 173 KSP-CFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQ 223 >6BQM-A nrPDB Length = 506 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 62/253 (24%), Positives = 106/253 (41%), Gaps = 48/253 (18%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVV 84 ++ I+GG +A PYM +L R N FCGG+ + +VLTAAHC+ +V+ Sbjct: 8 SSRIIGGEQATAGEWPYMVALTAR-NSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVL 66 Query: 85 LGAHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLS------SPANLSASVATV 137 LGA ++ T + V Q+++ N+Y + ND+ +++L +S S Sbjct: 67 LGAFDMNDVN-TAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDFN 125 Query: 138 QLPQQDQPVPHGTQCLAMGWGR----VGAHDPPAQVLQELNVTVVTF------------- 180 +L +D P+ +G+G G PA +L ++ V V Sbjct: 126 ELT-KDSPMT------VIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAK 178 Query: 181 --FCRPHNICTFVPRRKAGICFGDSGGPLICD--------GIIQGIDSFVIWGCATRLFP 230 + + N C GD+GGP+ D G++ D GC P Sbjct: 179 NNYSQLTNNAFCAGSFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGD-----GCGRANSP 233 Query: 231 DFFTRVALYVDWI 243 +T ++++ DW+ Sbjct: 234 GVYTNLSVFNDWL 246 >1ELV-A nrPDB Length = 333 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 104/261 (39%), Gaps = 56/261 (21%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG +A + P+ NP + GG LI+ +VLTAAH + R + +G+ Sbjct: 83 IIGGSDADIKNFPWQVFFD---NP---WAGGALINEYWVLTAAHVVEG--NREPTMYVGS 134 Query: 88 HNVRTQE-PTQQHFSVAQVFLN-------------NYDAENKLNDVLLIQLSSPANLSAS 133 +V+T + + VF++ N+D ND+ L++L P + + Sbjct: 135 TSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFD-----NDIALVRLKDPVKMGPT 189 Query: 134 VATVQLP--QQDQPVPHGTQCLAMGWGRVGAHD------------PPAQVLQELNVTVVT 179 V+ + LP D + G L GWGR D P + +E+ V T Sbjct: 190 VSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPT 249 Query: 180 -----FFCRPHNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWG--CATRL 228 + P+ IC + C GDSGG D V WG C T Sbjct: 250 ADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY- 307 Query: 229 FPDFFTRVALYVDWIRSTLRR 249 +TRV YVDWI T++ Sbjct: 308 --GLYTRVKNYVDWIMKTMQE 326 >1EPT-B nrPDB Length = 82 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 32/79 (40%), Positives = 48/79 (60%), Gaps = 3/79 (3%) Query: 81 VNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQL 139 + V LG HN+ E +Q + A++ + N++ ND++LI+LSSPA L++ VATV L Sbjct: 3 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 62 Query: 140 PQQDQPVPHGTQCLAMGWG 158 P+ GT+CL GWG Sbjct: 63 PRSCAAA--GTECLISGWG 79 >4J1Y-A nrPDB Length = 397 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 69/265 (26%), Positives = 103/265 (38%), Gaps = 56/265 (21%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 A +GG +A + P+ NP + GG LI+ +VLTAAH + R + Sbjct: 143 EKARAIGGSDADIKNFPWQVFFD---NP---WAGGALINEYWVLTAAHVVEG--NREPTM 194 Query: 84 VLGAHNVRTQE-PTQQHFSVAQVFL-------------NNYDAENKLNDVLLIQLSSPAN 129 +G+ +V+T + + VF+ N+D ND+ L++L P Sbjct: 195 YVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFD-----NDIALVRLKDPVK 249 Query: 130 LSASVATVQLP--QQDQPVPHGTQCLAMGWGRVGAHD------------PPAQVLQELNV 175 + +V+ + LP D + G L GWGR D P + +E+ V Sbjct: 250 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV 309 Query: 176 TVVT-----FFCRPHNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWG--C 224 T + P+ IC + C GDSGG D V WG C Sbjct: 310 EKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC 368 Query: 225 ATRLFPDFFTRVALYVDWIRSTLRR 249 T +TRV YVDWI T++ Sbjct: 369 GTY---GLYTRVKNYVDWIMKTMQE 390 >1VR1-H nrPDB Length = 261 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 111/261 (42%), Gaps = 44/261 (16%) Query: 28 IVGGHEAQPHSRPYMASL--QMRGNPGSHF-CGGTLIHPSFVLTAAHCL------RDIPQ 78 IV G +A+ P+ L + R +PG F CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 79 RLVNVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVA 135 + V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 136 TVQLPQQDQP---VPHGTQCLAMGWG--------RVGAHDPPAQVLQELNVTVVTF-FCR 183 V LP ++ + G + GWG VG P VLQ +N+ +V C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQP--SVLQVVNLPIVERPVCK 178 Query: 184 PHN--------ICTFVP---RRKAGICFGDSGGPLICDGIIQ------GIDSFVIWGCAT 226 C + ++ C GDSGGP + GI S+ GC Sbjct: 179 DSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDR 237 Query: 227 RLFPDFFTRVALYVDWIRSTL 247 F+T V WI+ + Sbjct: 238 DGKYGFYTHVFRLKKWIQKVI 258 >3H7T-A nrPDB Length = 235 Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 54/236 (22%), Positives = 95/236 (40%), Gaps = 24/236 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG ++ P+ + + P FCGG+++ +FV+TAA C+ +++ G+ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKP---FCGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQPV 146 + RT + T ++++ Y N+ +I+ P L + ++LP Sbjct: 58 -SYRTTKGTS--VMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDP 114 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVV--------------TFFCRPHNICTFV 191 T L GWG + L E N TVV + C Sbjct: 115 EPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGG 174 Query: 192 PRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + I +GD+G P + +G + G+ S++ FP F RV YV I+ + Sbjct: 175 EYDETYIGYGDAGDPAVQNGTLVGVASYI--SSMPSEFPSVFLRVGYYVLDIKDII 228 >3NXP-A nrPDB Length = 424 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/265 (25%), Positives = 109/265 (41%), Gaps = 56/265 (21%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 166 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 224 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 225 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 284 Query: 139 LPQQDQP---VPHGTQCLAMGWG--------RVGAHDPPAQVLQELNVTVVTFFCRPHNI 187 LP ++ + G + GWG VG P VLQ +N+ +V RP + Sbjct: 285 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQP--SVLQVVNLPIVE---RP--V 337 Query: 188 CTFVPR-----------------RKAGICFGDSGGPLICDGIIQ------GIDSFVIW-- 222 C R ++ C GDSGGP + GI V W Sbjct: 338 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGI---VSWGE 394 Query: 223 GCATRLFPDFFTRVALYVDWIRSTL 247 GC F+T V WI+ + Sbjct: 395 GCDRDGKYGFYTHVFRLKKWIQKVI 419 >3I77-A nrPDB Length = 230 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 94/239 (39%), Gaps = 29/239 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L N G FCGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG--FCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V + E D LI+L+ P N + +AT Q Sbjct: 59 V-VDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQ--- 114 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHN---------ICTFVPRRK 195 GT +A GWG + L + NV V+ CR + IC P Sbjct: 115 ---GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 196 A-GICFGDSGGPLI----CDGIIQ-GIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP+ D IQ GI S+ +GCA +P +T V+ + I S R Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASAIASAAR 228 >4NZQ-A nrPDB Length = 557 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/265 (26%), Positives = 108/265 (40%), Gaps = 56/265 (21%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 299 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 357 Query: 82 NVVLGAHNVRTQEPTQQHFSV-AQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ E + S+ +++++ Y+ L+ D+ L++L P S + V Sbjct: 358 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 417 Query: 139 LPQQDQP---VPHGTQCLAMGWG--------RVGAHDPPAQVLQELNVTVVTFFCRPHNI 187 LP ++ + G + GWG VG P VLQ +N+ +V RP + Sbjct: 418 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQP--SVLQVVNLPIVE---RP--V 470 Query: 188 CTFVPR-----------------RKAGICFGDSGGPLICDGIIQ------GIDSFVIW-- 222 C R ++ C GDSGGP + GI V W Sbjct: 471 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGI---VSWGE 527 Query: 223 GCATRLFPDFFTRVALYVDWIRSTL 247 GC F+T V WI+ + Sbjct: 528 GCDRDGKYGFYTHVFRLKKWIQKVI 552 >3K65-B nrPDB Length = 308 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 109/265 (41%), Gaps = 56/265 (21%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 50 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 108 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 109 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 168 Query: 139 LPQQDQP---VPHGTQCLAMGWG--------RVGAHDPPAQVLQELNVTVVTFFCRPHNI 187 LP ++ + G + GWG VG P VLQ +N+ +V RP + Sbjct: 169 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQP--SVLQVVNLPIVE---RP--V 221 Query: 188 CTFVPR-----------------RKAGICFGDSGGPLICDGIIQ------GIDSFVIW-- 222 C R ++ C GD+GGP + GI V W Sbjct: 222 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGI---VSWGE 278 Query: 223 GCATRLFPDFFTRVALYVDWIRSTL 247 GC F+T V WI+ + Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVI 303 >1MKW-K nrPDB Length = 308 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 67/266 (25%), Positives = 108/266 (40%), Gaps = 52/266 (19%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 50 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ + L+ D+ L++L P LS + V Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 139 LPQQDQPVP---HGTQCLAMGWGR------VGAHDPPAQVLQELNVTVVTFFCRPHNICT 189 LP + G + GWG + VLQ +N+ +V RP +C Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVE---RP--VCK 223 Query: 190 FVPR-----------------RKAGICFGDSGGPLICDG------IIQGIDSFVIW--GC 224 R ++ C GDSGGP + GI V W GC Sbjct: 224 ASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGI---VSWGEGC 280 Query: 225 ATRLFPDFFTRVALYVDWIRSTLRRV 250 F+T V WI+ + R+ Sbjct: 281 DRDGKYGFYTHVFRLKKWIQKVIDRL 306 >1ETT-H nrPDB Length = 259 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 108/264 (40%), Gaps = 48/264 (18%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ + L+ D+ L++L P LS + V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 139 LPQQDQPVP---HGTQCLAMGWGR------VGAHDPPAQVLQELNVTVVTFFCRPHNICT 189 LP + G + GWG + VLQ +N+ +V RP +C Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVE---RP--VCK 174 Query: 190 FVPR-----------------RKAGICFGDSGGPLICDG------IIQGIDSFVIWGCAT 226 R ++ C GDSGGP + GI S+ GC Sbjct: 175 ASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GCDR 233 Query: 227 RLFPDFFTRVALYVDWIRSTLRRV 250 F+T V WI+ + R+ Sbjct: 234 DGKYGFYTHVFRLKKWIQKVIDRL 257 >2OCV-B nrPDB Length = 259 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 61/259 (23%), Positives = 106/259 (40%), Gaps = 44/259 (16%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHC+ ++ + + Sbjct: 1 IVEGWDAEKGIAPWQVML-FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 139 LPQQDQPVP---HGTQCLAMGWGRV------GAHDPPAQVLQELNVTVV----------- 178 LP + G + GWG + ++ VLQ +N+ +V Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRI 179 Query: 179 ----TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQ------GIDSFVIWGCATRL 228 FC + ++ C GDSGGP + GI S+ GC + Sbjct: 180 RITDNMFCAGFKVND---TKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRKG 235 Query: 229 FPDFFTRVALYVDWIRSTL 247 F+T V WI+ + Sbjct: 236 KYGFYTHVFRLKAWIQKVI 254 >5TO3-B nrPDB Length = 409 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 57/218 (26%), Positives = 95/218 (43%), Gaps = 45/218 (20%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWG--------RVGAHDPPAQVLQELNVTVVTFFCRPHNI 187 LP ++ + G + GWG VG P VLQ +N+ +V RP + Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQP--SVLQVVNLPIVE---RP--V 172 Query: 188 CTFVPR-----------------RKAGICFGDSGGPLI 208 C R ++ C GDSGGP + Sbjct: 173 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 210 >1AKS-B nrPDB Length = 98 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 26/61 (42%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Query: 187 ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 IC + C GDSGGP++C+G +QGI S+ +GCA + P +T+V YV+WI+ T Sbjct: 36 ICVGFLQGGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQT 94 Query: 247 L 247 + Sbjct: 95 I 95 >2QY0-B nrPDB Length = 242 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 64/251 (25%), Positives = 97/251 (38%), Gaps = 36/251 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-----VN 82 I+GG +A+ + P+ + G G G L+ ++LTAAH L ++ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRGG-----GALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 83 VVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLN---DVLLIQLSSPANLSASVATVQ 138 V LG NV H + +V ++ +Y + N D+ L++L + L ++ + Sbjct: 56 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 114 Query: 139 LPQQDQPVPHGTQCLAMGWGRVG---AHDPPAQVLQELNVTVVTFFCRPHN--------- 186 LP D G G+G + AHD L N + R N Sbjct: 115 LPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNM 174 Query: 187 ICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 C P K C GDSGG P + GI V WG F+T+V YV Sbjct: 175 FCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGI---VSWGIGCSRGYGFYTKVLNYV 231 Query: 241 DWIRSTLRRVE 251 DWI+ + + Sbjct: 232 DWIKKEMEEED 242 >1GPZ-A nrPDB Length = 399 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 98/252 (38%), Gaps = 36/252 (14%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-----V 81 +I+GG +A+ + P+ + G G G L+ ++LTAAH L + Sbjct: 157 QIIGGQKAKMGNFPWQVFTNIHGRGG-----GALLGDRWILTAAHTLYPKEHEAQSNASL 211 Query: 82 NVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLN---DVLLIQLSSPANLSASVATV 137 +V LG NV H + +V ++ +Y + N D+ L++L + L ++ + Sbjct: 212 DVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 270 Query: 138 QLPQQDQPVPHGTQCLAMGWGRVG---AHDPPAQVLQELNVTVVTFFCRPHN-------- 186 LP D G G+G + AHD L N + R N Sbjct: 271 CLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 330 Query: 187 -ICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALY 239 C P K C GDSGG P + GI V WG F+T+V Y Sbjct: 331 MFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGI---VSWGIGCSRGYGFYTKVLNY 387 Query: 240 VDWIRSTLRRVE 251 VDWI+ + + Sbjct: 388 VDWIKKEMEEED 399 >3BEU-A nrPDB Length = 224 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 91/240 (37%), Gaps = 37/240 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L M CGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V + E D LI+L+ P N + +AT Q Sbjct: 54 V-VDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQ--- 109 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHN---------ICTFVPRRK 195 GT +A GWG + L + NV V+ CR + IC ++ Sbjct: 110 ---GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQ 165 Query: 196 AGICFGDSGGPLI----CDGIIQ-GIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP+ D +Q GI V W GCA + +T V+ + I S R Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGI---VSWGEGCARKGKYGVYTEVSTFASAIASAAR 222 >1MD7-A nrPDB Length = 328 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 36/248 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-----VN 82 I+GG +A+ + P+ + G G G L+ ++LTAAH L ++ Sbjct: 90 IIGGQKAKMGNFPWQVFTNIHGRGG-----GALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 83 VVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLN---DVLLIQLSSPANLSASVATVQ 138 V LG NV H + +V ++ +Y + N D+ L++L + L ++ + Sbjct: 145 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 203 Query: 139 LPQQDQPVPHGTQCLAMGWGRVG---AHDPPAQVLQELNVTVVTFFCRPHN--------- 186 LP D G G+G + AHD L N + R N Sbjct: 204 LPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNM 263 Query: 187 ICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 C P K C GD+GG P + GI V WG F+T+V YV Sbjct: 264 FCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGI---VSWGIGCSRGYGFYTKVLNYV 320 Query: 241 DWIRSTLR 248 DWI+ + Sbjct: 321 DWIKKEME 328 >2KAI-A nrPDB Length = 80 Score = 52.8 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 7/79 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E + +S P+ ++ + S CGG L++P +VLTAAHC D + V LG Sbjct: 1 IIGGRECEKNSHPWQVAIY---HYSSFQCGGVLVNPKWVLTAAHCKNDNYE----VWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVF 106 HN+ E T Q F V F Sbjct: 54 HNLFENENTAQFFGVTADF 72 >1RIW-B nrPDB Length = 147 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 13/145 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGRV 160 LP ++ + G + GWG + Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNL 144 >1BBR-H nrPDB Length = 150 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 39/143 (27%), Positives = 70/143 (48%), Gaps = 13/143 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 82 NVVLGAHN-VRTQEPTQQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ R + ++ + +++++ Y+ + L+ D+ L++L P LS + V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 139 LPQQD---QPVPHGTQCLAMGWG 158 LP + + + G + GWG Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWG 142 >2FMJ-A nrPDB Length = 222 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 89/240 (37%), Gaps = 39/240 (16%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L M CGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V Y+ K D LI+L+ P N + +AT Q Sbjct: 54 V-VDLQSSSAVKVRSTKVLQAPGYNGTGK--DWALIKLAQPINQPTLKIATTTAYNQ--- 107 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRP---------HNICTFVPRRK 195 GT +A GWG + L + NV V+ CR IC Sbjct: 108 ---GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 196 AGICFGDSGGPLI----CDGIIQ-GIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP+ D IQ GI V W GCA + +T V+ + I S R Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGI---VSWGEGCARKGKYGVYTEVSTFASAIASAAR 220 >3F1S-B nrPDB Length = 283 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 11/123 (8%) Query: 45 LQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRT-QEPTQQHFSVA 103 +++ + G FCGG +I +FVLT A C + R N+ + + RT Q+P + Sbjct: 68 VKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHR--NITVKTYFNRTSQDPLMIKITHV 123 Query: 104 QVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP----VPHGTQCLAMGWGR 159 V + YDA+ ND+ L++L P + V P++D +P T+ L GW R Sbjct: 124 HVHM-RYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPR-TRGLLSGWAR 181 Query: 160 VGA 162 G Sbjct: 182 NGT 184 >3H5C-B nrPDB Length = 317 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 9/122 (7%) Query: 45 LQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQ 104 +++ + G FCGG +I +FVLT A C + R + V N +Q+P + Sbjct: 109 VKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITVKT-YFNRTSQDPLMIKITHVH 165 Query: 105 VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP----VPHGTQCLAMGWGRV 160 V + YDA+ ND+ L++L P + V P++D +P T+ L GW R Sbjct: 166 VHM-RYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPR-TRGLLSGWARN 223 Query: 161 GA 162 G Sbjct: 224 GT 225 >1ZJK-A nrPDB Length = 403 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 31/254 (12%) Query: 19 LSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ 78 LS +I GG +A+P P+ + G G L++ ++VLTAAH + + Sbjct: 153 LSARTTGGQIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 207 Query: 79 RLVNVVLGAHNVRTQEP-TQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSPANLSASVAT 136 + + ++ P Q +S A Y + ND+ LI+L++ +++++ Sbjct: 208 DASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 267 Query: 137 VQLPQQDQPVPHGTQCL--AMGWGRVGAHDPPAQVLQELNVTVVTF------FCRP---- 184 + LP+++ T + A GWG + A+ L +++ +V + +P Sbjct: 268 ICLPRKEAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPR 326 Query: 185 -----HNICTFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFF 233 + +C + C GDSGG L+ + GI S+ C + Sbjct: 327 GSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVY 386 Query: 234 TRVALYVDWIRSTL 247 T+V Y+ WI + + Sbjct: 387 TKVINYIPWIENII 400 >1Q3X-A nrPDB Length = 328 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 55/254 (21%), Positives = 104/254 (40%), Gaps = 31/254 (12%) Query: 19 LSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ 78 LS I GG +A+P P+ + G G L++ ++VLTAAH + + Sbjct: 78 LSARTTGGRIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 132 Query: 79 RLVNVVLGAHNVRTQEP-TQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSPANLSASVAT 136 + + ++ P Q +S A Y + ND+ LI+L++ +++++ Sbjct: 133 DASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 192 Query: 137 VQLPQQDQPVPHGTQCL--AMGWGRVGAHDPPAQVLQELNVTVVTF------FCRP---- 184 + LP+++ T + A GWG + A+ L +++ +V + +P Sbjct: 193 ICLPRKEAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPR 251 Query: 185 -----HNICTFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFF 233 + +C + C GDSGG L+ + GI S+ C + Sbjct: 252 GSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVY 311 Query: 234 TRVALYVDWIRSTL 247 T+V Y+ WI + + Sbjct: 312 TKVINYIPWIENII 325 >4FXG-H nrPDB Length = 242 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 52/245 (21%), Positives = 102/245 (41%), Gaps = 31/245 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I GG +A+P P+ + G G L++ ++VLTAAH + + + + Sbjct: 1 IYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 88 HNVRTQEP-TQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSPANLSASVATVQLPQQDQP 145 ++ P Q +S A Y + ND+ LI+L++ +++++ + LP+++ Sbjct: 56 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 115 Query: 146 VPHGTQCL--AMGWGRVGAHDPPAQVLQELNVTVVTF------FCRP---------HNIC 188 T + A GWG + A+ L +++ +V + +P + +C Sbjct: 116 SFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLC 174 Query: 189 TFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 + C GD+GG L+ + GI S+ C +T+V Y+ W Sbjct: 175 AGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPW 234 Query: 243 IRSTL 247 I + + Sbjct: 235 IENII 239 >1DLE-A nrPDB Length = 298 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 82/237 (34%), Gaps = 57/237 (24%) Query: 37 HSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVRTQE 94 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G E Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG------E 78 Query: 95 PTQQHFSVAQVFLNNYDAENKLN---------DVLLIQLSSPANLSASVATVQLPQQDQP 145 V +F NY+ K DV LI+L + ++ + LP + Sbjct: 79 KRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 137 Query: 146 -----VPHGTQCLAMGWGRVGAHDPPAQVLQEL--------------------------- 173 +P T C + A D A + E Sbjct: 138 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 197 Query: 174 ----NVTVVTFFCRPHNICT--FVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-WG 223 V ++ P +CT P C GDSGGPLI + I VI WG Sbjct: 198 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 >2OK5-A nrPDB Length = 752 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 82/237 (34%), Gaps = 57/237 (24%) Query: 37 HSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVRTQE 94 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G E Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG------E 529 Query: 95 PTQQHFSVAQVFLNNYDAENKLN---------DVLLIQLSSPANLSASVATVQLPQQDQP 145 V +F NY+ K DV LI+L + ++ + LP + Sbjct: 530 KRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 588 Query: 146 -----VPHGTQCLAMGWGRVGAHDPPAQVLQEL--------------------------- 173 +P T C + A D A + E Sbjct: 589 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 648 Query: 174 ----NVTVVTFFCRPHNICT--FVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-WG 223 V ++ P +CT P C GDSGGPLI + I VI WG Sbjct: 649 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 >2WIN-I nrPDB Length = 507 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 82/237 (34%), Gaps = 57/237 (24%) Query: 37 HSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVRTQE 94 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G E Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG------E 285 Query: 95 PTQQHFSVAQVFLNNYDAENKLN---------DVLLIQLSSPANLSASVATVQLPQQDQP 145 V +F NY+ K DV LI+L + ++ + LP + Sbjct: 286 KRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 344 Query: 146 -----VPHGTQCLAMGWGRVGAHDPPAQVLQEL--------------------------- 173 +P T C + A D A + E Sbjct: 345 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 404 Query: 174 ----NVTVVTFFCRPHNICT--FVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-WG 223 V ++ P +CT P C GDSGGPLI + I VI WG Sbjct: 405 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 >3RU4-E nrPDB Length = 96 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 199 CFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL+C + GI S+ C+T P + RV V+W++ TL Sbjct: 42 CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTST-PGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 7/55 (12%) Query: 199 CFGDSGGPLIC--DGIIQGIDSFVIWG---CATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C DG+ + V WG C+T P ++RV + W++ L Sbjct: 45 CMGDSGGPLVCQKDGVWT-LAGIVSWGSGVCSTST-PGVYSRVTALMPWVQQILE 97 >2HNT-C nrPDB Length = 70 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL 73 IV G +A+ P+ L R +P CG +LI +VLTAAHCL Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCL 45 >2I6S-A nrPDB Length = 517 Score = 32.0 bits (71), Expect = 0.24, Method: Compositional matrix adjust. Identities = 13/20 (65%), Positives = 14/20 (70%) Query: 56 CGGTLIHPSFVLTAAHCLRD 75 C G LI +VLTAAHC RD Sbjct: 257 CRGALISDQWVLTAAHCFRD 276 >1P3E-A nrPDB Length = 215 Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 16/28 (57%) Query: 52 GSHFCGGTLIHPSFVLTAAHCLRDIPQR 79 G C GTLI P+ +LT HC+ + R Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASR 55 >1ZCB-A nrPDB Length = 362 Score = 30.4 bits (67), Expect = 0.72, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 17/33 (51%) Query: 71 HCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVA 103 HCLRD+ + LV G + Q P HF+ A Sbjct: 302 HCLRDVQKFLVECFRGKRRDQQQRPLYHHFTTA 334 >3AHE-A nrPDB Length = 845 Score = 28.9 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 17/93 (18%) Query: 87 AHNV--RTQEPTQQHFSVAQVFLNNYDAENKLN-------DV--------LLIQLSSPAN 129 AH V + T++HF V + ++ +Y E N DV L I + AN Sbjct: 339 AHQVPLASARDTEEHFEVLKGWMESYKPEELFNADGSIKDDVTAFMPKGELRIGANPNAN 398 Query: 130 LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGA 162 ++LP+ DQ G + GWG+V A Sbjct: 399 GGVIREDLKLPELDQYEVTGVKEYGHGWGQVEA 431 >2B0O-E nrPDB Length = 301 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 1/97 (1%) Query: 31 GHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHN 89 GH+ +PH + +++ PG S C P+++ T L I V+ LG Sbjct: 20 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 79 Query: 90 VRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSS 126 R Q T +++ L N+V+ QL S Sbjct: 80 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPS 116 >2WIY-A nrPDB Length = 394 Score = 27.7 bits (60), Expect = 4.5, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 15 LALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLR 74 + ++ A R E+ + H+RP AS + G H C G +I + T L Sbjct: 304 IRFMIGAANRDPEVFDDPDVFDHTRPPAASRNLSFGLGPHSCAGQIISRAEATTVFAVLA 363 Query: 75 DIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVF 106 + +R+ +EPT H A+ + Sbjct: 364 ERYERI---------ELAEEPTVAHNDFARRY 386 >3LVQ-E nrPDB Length = 497 Score = 27.7 bits (60), Expect = 4.8, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 1/97 (1%) Query: 31 GHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHN 89 GH+ +PH + +++ PG S C P+++ T L I V+ LG Sbjct: 1 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 60 Query: 90 VRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSS 126 R Q T +++ L N+V+ QL S Sbjct: 61 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPS 97 >5LAK-A nrPDB Length = 314 Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust. Identities = 30/126 (23%), Positives = 44/126 (34%), Gaps = 13/126 (10%) Query: 56 CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENK 115 CGG L P L HC ++ G N+ T QH S + LNN Sbjct: 153 CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKL-QHPSEIMITLNN------ 205 Query: 116 LNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELN 174 I L +PAN V + V + L + A P +++L + N Sbjct: 206 -----EINLPNPANYDFETTKVVYQHPLRNVCATLETLQHLTNKTNAKLPYDSRLLSDFN 260 Query: 175 VTVVTF 180 +T + Sbjct: 261 ITAEQY 266 >5XIG-A nrPDB Length = 500 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 9/55 (16%) Query: 114 NKLNDVLLIQL-SSPANLSASVATVQLPQQDQPVPHGTQCLAMG--------WGR 159 KL+++ I+ S ++ ++ T+ +P P+P GT+C G WGR Sbjct: 444 QKLSEIQAIEAGDSEQVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGR 498 >2GRV-A nrPDB Length = 621 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 124 LSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCR 183 LS + ++A++A++ LP +PVP T W A+V QE N VT+ R Sbjct: 66 LSDQSPVNAAIASLVLPSSFRPVPDPTSPTGSRWELDTTLLESAEVTQE-NPFTVTYKIR 124 Query: 184 PH 185 P Sbjct: 125 PE 126 >5ZT8-A nrPDB Length = 273 Score = 26.9 bits (58), Expect = 9.7, Method: Compositional matrix adjust. Identities = 11/21 (52%), Positives = 14/21 (66%) Query: 63 PSFVLTAAHCLRDIPQRLVNV 83 P +LTAAH DIP+ +V V Sbjct: 80 PLLLLTAAHAKHDIPEEIVRV 100 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FUJ-A nrPDB 341 1e-94 1UTJ-A nrPDB 293 6e-80 6I44-A nrPDB 289 8e-79 5TJX-A nrPDB 287 3e-78 4AN7-A nrPDB 284 2e-77 1F7Z-A nrPDB 283 5e-77 5FXL-A nrPDB 280 3e-76 1A0J-A nrPDB 278 2e-75 1EUF-A nrPDB 277 3e-75 4WWY-A nrPDB 276 6e-75 5C67-A nrPDB 275 2e-74 5GVT-A nrPDB 273 4e-74 1FI8-A nrPDB 270 3e-73 2F83-A nrPDB 269 1e-72 1FXY-A nrPDB 264 3e-71 4DUR-A nrPDB 262 1e-70 5UGG-A nrPDB 262 2e-70 1IAU-A nrPDB 262 2e-70 1SGF-G nrPDB 259 7e-70 1PPF-E nrPDB 259 1e-69 1BRU-P nrPDB 259 1e-69 2EEK-A nrPDB 258 1e-69 3W94-A nrPDB 257 3e-69 1NN6-A nrPDB 257 3e-69 6AOD-C nrPDB 257 4e-69 2TLD-E nrPDB 256 5e-69 1X7A-C nrPDB 256 8e-69 4NFE-A nrPDB 255 9e-69 3T2N-A nrPDB 255 1e-68 3LC3-A nrPDB 253 7e-68 4H4F-A nrPDB 253 7e-68 3E0N-B nrPDB 252 8e-68 1KIG-H nrPDB 252 1e-67 3TK9-A nrPDB 252 2e-67 4MPW-A nrPDB 251 2e-67 1C5M-D nrPDB 250 5e-67 3G01-A nrPDB 250 6e-67 4DGJ-A nrPDB 249 7e-67 1P57-B nrPDB 249 7e-67 1NPM-A nrPDB 248 1e-66 1LTO-A nrPDB 247 3e-66 3QUM-P nrPDB 247 3e-66 1EKB-B nrPDB 247 5e-66 3DFJ-A nrPDB 247 5e-66 5MS3-A nrPDB 246 8e-66 3BSQ-A nrPDB 246 8e-66 2F91-A nrPDB 245 1e-65 3P8G-A nrPDB 245 1e-65 1AE5-A nrPDB 245 1e-65 1SPJ-A nrPDB 245 2e-65 1AO5-A nrPDB 244 3e-65 3RP2-A nrPDB 243 4e-65 1FDP-A nrPDB 243 6e-65 1PYT-D nrPDB 243 6e-65 2RDL-A nrPDB 242 1e-64 3K65-B nrPDB 242 2e-64 1TON-A nrPDB 242 2e-64 1BDA-A nrPDB 242 2e-64 3NXP-A nrPDB 241 2e-64 2PSX-A nrPDB 241 2e-64 2V35-A nrPDB 241 3e-64 1MKW-K nrPDB 241 3e-64 4NZQ-A nrPDB 240 4e-64 5ZFH-A nrPDB 240 6e-64 6QHB-A nrPDB 239 9e-64 1FIZ-A nrPDB 239 9e-64 1YC0-A nrPDB 238 1e-63 1ORF-A nrPDB 238 1e-63 1ELT-A nrPDB 238 2e-63 3S9B-A nrPDB 237 4e-63 4GSO-A nrPDB 237 5e-63 2BDH-A nrPDB 237 5e-63 2AIQ-A nrPDB 236 6e-63 2CGA-A nrPDB 236 7e-63 5LHN-A nrPDB 235 1e-62 1MZD-A nrPDB 235 1e-62 5FCR-A nrPDB 235 1e-62 4Q7Y-A nrPDB 235 1e-62 1FIW-A nrPDB 235 1e-62 2R0L-A nrPDB 235 1e-62 2OCV-B nrPDB 235 2e-62 1A5I-A nrPDB 234 4e-62 4Z6A-H nrPDB 233 4e-62 1KYN-A nrPDB 233 5e-62 1ETT-H nrPDB 233 5e-62 1SC8-U nrPDB 233 7e-62 1VR1-H nrPDB 232 1e-61 1SGF-A nrPDB 232 1e-61 4E7N-A nrPDB 232 1e-61 2OQ5-A nrPDB 231 2e-61 4XDE-A nrPDB 231 3e-61 1FON-A nrPDB 230 6e-61 1GVZ-A nrPDB 229 8e-61 5TO3-B nrPDB 225 1e-59 2ZKS-A nrPDB 225 1e-59 3F6U-H nrPDB 225 1e-59 4BXW-A nrPDB 225 2e-59 1Q3X-A nrPDB 223 6e-59 1OP0-A nrPDB 223 8e-59 1ZJK-A nrPDB 220 3e-58 1BQY-A nrPDB 219 7e-58 1AZZ-A nrPDB 218 2e-57 2XXL-A nrPDB 216 7e-57 4FXG-H nrPDB 215 2e-56 4IW4-E nrPDB 214 3e-56 5XRF-A nrPDB 214 3e-56 4KKD-A nrPDB 213 4e-56 3S69-A nrPDB 213 4e-56 4LK4-A nrPDB 212 1e-55 1EQ9-A nrPDB 210 5e-55 1YM0-A nrPDB 208 2e-54 5LPF-A nrPDB 207 3e-54 2OLG-A nrPDB 206 8e-54 2XRC-A nrPDB 205 1e-53 2QY0-B nrPDB 205 2e-53 4IGD-A nrPDB 204 3e-53 1GPZ-A nrPDB 204 4e-53 5KWM-A nrPDB 202 1e-52 4DJZ-B nrPDB 201 2e-52 2B9L-A nrPDB 200 7e-52 1MD7-A nrPDB 199 9e-52 5O32-I nrPDB 198 1e-51 5UBM-A nrPDB 195 2e-50 6BQM-A nrPDB 193 4e-50 1ELV-A nrPDB 192 1e-49 1SI5-H nrPDB 192 1e-49 2ASU-B nrPDB 191 2e-49 3H7O-A nrPDB 189 1e-48 3I77-A nrPDB 189 1e-48 1M9U-A nrPDB 188 2e-48 4J1Y-A nrPDB 187 3e-48 3BEU-A nrPDB 181 2e-46 2HLC-A nrPDB 180 4e-46 1PQ7-A nrPDB 180 5e-46 3H7T-A nrPDB 177 3e-45 5XW8-A nrPDB 174 3e-44 2FMJ-A nrPDB 173 5e-44 2PKA-B nrPDB 165 2e-41 3VGC-B nrPDB 163 9e-41 2JET-B nrPDB 159 7e-40 1RIW-B nrPDB 158 3e-39 1BBR-H nrPDB 151 3e-37 1DLE-A nrPDB 136 7e-33 1AKS-B nrPDB 118 3e-27 3F1S-B nrPDB 108 2e-24 3H5C-B nrPDB 106 1e-23 2KAI-A nrPDB 105 2e-23 1EPT-B nrPDB 104 5e-23 Sequences not found previously or not previously below threshold: 4F4O-C nrPDB 141 2e-34 4X0L-C nrPDB 139 2e-33 2WIN-I nrPDB 139 2e-33 4WJG-C nrPDB 138 2e-33 2OK5-A nrPDB 135 2e-32 2I6S-A nrPDB 106 7e-24 1BBR-E nrPDB 93 2e-19 2HNT-F nrPDB 92 3e-19 2HNT-C nrPDB 86 2e-17 3RU4-E nrPDB 81 4e-16 2JET-C nrPDB 80 1e-15 2HNT-E nrPDB 78 6e-15 1P3E-A nrPDB 45 4e-05 1DUE-A nrPDB 36 0.023 3LT3-A nrPDB 35 0.027 2EA3-A nrPDB 35 0.029 2OUA-A nrPDB 34 0.073 2SFA-A nrPDB 34 0.078 2PFE-A nrPDB 33 0.15 2SGA-A nrPDB 32 0.27 5XIG-A nrPDB 31 0.70 5XIP-A nrPDB 31 0.71 4NCX-A nrPDB 30 1.2 5ILB-A nrPDB 29 1.8 4FLN-A nrPDB 29 1.8 4FVB-A nrPDB 29 1.8 3W95-A nrPDB 29 1.9 3STJ-A nrPDB 29 2.9 3STI-A nrPDB 29 2.9 5X88-A nrPDB 28 3.8 1HPG-A nrPDB 28 4.2 2BS9-A nrPDB 28 4.5 2HRV-A nrPDB 28 4.8 2M5T-A nrPDB 28 5.2 4A8B-A nrPDB 27 5.6 >1FUJ-A nrPDB Length = 221 Score = 341 bits (876), Expect = 1e-94, Method: Composition-based stats. Identities = 220/221 (99%), Positives = 221/221 (100%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 HNVRTQEPTQQHFSVAQVFLNNYDAENKLND+LLIQLSSPANLSASVATVQLPQQDQPVP Sbjct: 61 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVP 120 Query: 148 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 207 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL Sbjct: 121 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 180 Query: 208 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR Sbjct: 181 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1UTJ-A nrPDB Length = 242 Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats. Identities = 89/247 (36%), Positives = 137/247 (55%), Gaps = 24/247 (9%) Query: 14 LLALLLSGAARA---AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAA 70 L+ +LL GAA A +IVGG+E +P+S+P+ SL N G HFCGG+L++ ++V++AA Sbjct: 4 LVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVVSAA 59 Query: 71 HCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPAN 129 HC + V V LG HN++ E ++Q S ++V + NY + N ND++LI+LS PA Sbjct: 60 HCYKSR----VEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPAT 115 Query: 130 LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF--------- 180 L+ V V LP P GT C GWG + + LQ LN+ ++++ Sbjct: 116 LNTYVQPVALPTSCA--PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG 173 Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 C C GDSGGP++C+G +QG+ S+ +GCA P + +V ++ Sbjct: 174 MITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFN 232 Query: 241 DWIRSTL 247 DW+ ST+ Sbjct: 233 DWLTSTM 239 >6I44-A nrPDB Length = 627 Score = 289 bits (740), Expect = 8e-79, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 109/250 (43%), Gaps = 21/250 (8%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QR 79 + IVGG ++ P+ SLQ++ H CGG+LI +VLTAAHC +P R Sbjct: 376 TSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 435 Query: 80 LVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQL 139 + + +L ++ P Q + + NY +D+ LI+L +P + + L Sbjct: 436 IYSGILQLSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICL 493 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICT 189 P + T C GWG +LQ++N+ +V + +C Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 553 Query: 190 FVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GD+GGPL+C + GI S+ GCA R P +T+VA Y+DWI Sbjct: 554 GYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILE 612 Query: 246 TLRRVEAKGR 255 + + K + Sbjct: 613 KTQSSDGKAQ 622 >5TJX-A nrPDB Length = 263 Score = 287 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%) Query: 21 GAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP--- 77 + IVGG E+ P+ SLQ++ H CGG+LI +VLTAAHC +P Sbjct: 9 TTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 68 Query: 78 -QRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVAT 136 R+ + +L ++ P Q + + NY +D+ LI+L +P + Sbjct: 69 VWRIYSGILELSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLEYTEFQKP 126 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHN 186 + LP + T C GWG +LQ++N+ +V + Sbjct: 127 ISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRM 186 Query: 187 ICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 +C C GDSGGPL+C + GI S+ GCA R P +T+VA Y+DW Sbjct: 187 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDW 245 Query: 243 IRSTLRRVEAKGR 255 I + + K + Sbjct: 246 ILEKTQSSDGKAQ 258 >4AN7-A nrPDB Length = 231 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 86/233 (36%), Positives = 127/233 (54%), Gaps = 22/233 (9%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 +IVGG+ +S PY SL N GSHFCGG+LI+ +V++AAHC + + V L Sbjct: 7 DKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRL 58 Query: 86 GAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 G HN+ E +Q + A++ N++ ND++LI+LSSPA L++ VATV LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 145 PVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFF---------CRPHNICTFVPRR 194 GT+CL GWG + +LQ L V++ + IC Sbjct: 119 --AAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEG 176 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QGI S+ +GCA + P +T+V YV+WI+ T+ Sbjct: 177 GKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTI 228 >1F7Z-A nrPDB Length = 233 Score = 283 bits (725), Expect = 5e-77, Method: Composition-based stats. Identities = 88/231 (38%), Positives = 125/231 (54%), Gaps = 22/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ Q +S PY SL N G HFCGG+LI+ +V++AAHC + + V LG Sbjct: 11 IVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCYKSR----IQVRLGE 62 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E +Q + A++ N+D + ND++LI+LSSP L+A VATV LP Sbjct: 63 HNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCA-- 120 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKA 196 P GTQCL GWG + +LQ L+ ++ + +C Sbjct: 121 PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGK 180 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QGI S+ +GCA P +T+V YVDWI+ T+ Sbjct: 181 DSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTI 230 >5FXL-A nrPDB Length = 246 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 84/251 (33%), Positives = 128/251 (50%), Gaps = 28/251 (11%) Query: 14 LLALLLSGAARA------AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVL 67 + L L GAA A +IVGG+ ++ PY SL N G HFCGG+LI+ +V+ Sbjct: 4 FIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVV 59 Query: 68 TAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSS 126 +AAHC + + V LG N+ E +Q S ++ ++ +Y++ ND++LI+L S Sbjct: 60 SAAHCYKS----GIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKS 115 Query: 127 PANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFF---- 181 A+L++ VA++ LP GTQCL GWG + VL+ L +++ Sbjct: 116 AASLNSRVASISLPTSCAS--AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKS 173 Query: 182 -----CRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRV 236 + C C GDSGGP++C G +QGI S+ GCA + P +T+V Sbjct: 174 AYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKV 232 Query: 237 ALYVDWIRSTL 247 YV WI+ T+ Sbjct: 233 CNYVSWIKQTI 243 >1A0J-A nrPDB Length = 223 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 22/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+E + +S Y ASLQ G HFCGG+LI ++V++AAHC + + V LG Sbjct: 1 IVGGYECRKNSASYQASLQ----SGYHFCGGSLISSTWVVSAAHCYKSR----IQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E T+Q +V ++ +Y++ N ND++LI+LS PA+L++ V+TV LP Sbjct: 53 HNIAVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASS 112 Query: 147 PHGTQCLAMGWGRV-GAHDPPAQVLQELNVTVVTFF---------CRPHNICTFVPRRKA 196 GT+CL GWG + G+ L+ L++ +++ + C Sbjct: 113 --GTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QG+ S+ +GCA R P +T+V Y WI ST+ Sbjct: 171 DSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTM 220 >1EUF-A nrPDB Length = 227 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 92/234 (39%), Positives = 135/234 (57%), Gaps = 17/234 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA L + + SH CGG L+ FVLTAAHCL +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGS----SINVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ +E TQQ V + + +Y+ E ND++L++L+ A+++ V+ + LP+ V Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKAG 197 G C GWGR+G + P LQE+++ V + + IC P ++ Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKN 176 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVE 251 GDSGGPL+C+G+ QGI S+ G PD +TR++ ++ WI ST+RR + Sbjct: 177 SFSGDSGGPLVCNGVAQGIVSY---GRNDGTTPDVYTRISSFLSWIHSTMRRYK 227 >4WWY-A nrPDB Length = 224 Score = 276 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 80/231 (34%), Positives = 122/231 (52%), Gaps = 22/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + +S PY SL N G HFCGG+LI+ +V++A HC + + V LG Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+ E +Q + A++ + YD + ND++LI+LSS A ++A V+T+ LP P Sbjct: 53 HNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA--PP 110 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKA 196 GT+CL GWG + LQ L+ V++ + C Sbjct: 111 ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C DSGGP++C+G +QG+ S+ GCA + P +T+V YV WI++T+ Sbjct: 171 DSCQRDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTI 220 >5C67-A nrPDB Length = 224 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 82/231 (35%), Positives = 124/231 (53%), Gaps = 22/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + +S PY SL N GSHFCGG+LI +V++AAHC + + V LG Sbjct: 1 IVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCYKTR----IQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ E +Q + A++ + Y+ + ND++LI+LSSPA ++A V+T+ LP P Sbjct: 53 HNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--PP 110 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKA 196 GT+CL GWG + L+ L+ V+T C Sbjct: 111 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C D+GGP++C+G +QG+ S+ GCA + P +T+V YVDWI+ T+ Sbjct: 171 DSCQRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 220 >5GVT-A nrPDB Length = 250 Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats. Identities = 65/243 (26%), Positives = 103/243 (42%), Gaps = 17/243 (6%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 86 IVGG A P+ SLQ++ +H CGG++I +VLTAAHC IP + + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 ++ + ++ ++ Y D+ LI+L +P N + + LP + Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICTFVPRRK 195 T C GWG +LQ+ + +V + IC Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGG 180 Query: 196 AGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVE 251 C GDSGGPL+C + GI S+ GCA + P +T+V+ Y+DWI + + Sbjct: 181 TDACKGDSGGPLVCKHSGRWQLVGITSWG-EGCARKDQPGVYTKVSEYMDWILEKTQSSD 239 Query: 252 AKG 254 + Sbjct: 240 VRA 242 >1FI8-A nrPDB Length = 228 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 88/235 (37%), Positives = 130/235 (55%), Gaps = 19/235 (8%) Query: 28 IVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GGHEA+PHSRPYMA LQ+ GS CGG LI FVLTAAHC + V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKIQVTLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AHN++ QE QQ V ++ + Y+++ ND++L++L S A S++V + LP+++ Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICTFVPRRK 195 V G C GWG++G + LQE+ +TV +F + + IC P+ K Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 GDSGGPL+C + GI S+ P FT+V+ ++ WI+ T+++ Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 228 >2F83-A nrPDB Length = 625 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 66/238 (27%), Positives = 98/238 (41%), Gaps = 17/238 (7%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVL 85 IVGG + P+ +L H CGG++I ++LTAAHC + +++ V Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 G N + F V ++ +++ Y D+ L++L + N + S + LP + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH---------NICTFVPRR 194 T C GWG D LQ+ + +V C+ IC Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 566 Query: 195 KAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL C + GI S+ GCA R P +T V YVDWI + Sbjct: 567 GKDACKGDSGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEYVDWILEKTQ 623 >1FXY-A nrPDB Length = 228 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 18/231 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ + P+ A L N G FCGGT++ ++LTAAHCL + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG--FCGGTILSEFYILTAAHCLY--QAKRFKVRVGD 56 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 N +E + V V N + E D+ +++L +P +VA LP P Sbjct: 57 RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--PP 114 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKA 196 GT+CL GWG + LQ L+ V++ + C Sbjct: 115 ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGK 174 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G +QG+ S+ GCA + P +T+V YV WI++T+ Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTI 224 >4DUR-A nrPDB Length = 791 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 85/239 (35%), Positives = 115/239 (48%), Gaps = 25/239 (10%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVV 84 +VGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL P V+ Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 617 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 LGAH EP Q V+++FL D+ L++LSSPA ++ V LP + Sbjct: 618 LGAHQEVNLEPHVQEIEVSRLFLEP-----TRKDIALLKLSSPAVITDKVIPACLPSPNY 672 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-----------CRPHNICTFVPR 193 V T+C GWG A +L+E + V+ + +C Sbjct: 673 VVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 731 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C I+QG+ S+ + GCA P + RV+ +V WI +R Sbjct: 732 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 789 >5UGG-A nrPDB Length = 251 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 85/239 (35%), Positives = 115/239 (48%), Gaps = 25/239 (10%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVV 84 +VGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL P V+ Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 77 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 LGAH EP Q V+++FL D+ L++LSSPA ++ V LP + Sbjct: 78 LGAHQEVNLEPHVQEIEVSRLFLEP-----TRKDIALLKLSSPAVITDKVIPACLPSPNY 132 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-----------CRPHNICTFVPR 193 V T+C GWG A +L+E + V+ + +C Sbjct: 133 VVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 191 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C I+QG+ S+ + GCA P + RV+ +V WI +R Sbjct: 192 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 249 >1IAU-A nrPDB Length = 227 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 88/234 (37%), Positives = 123/234 (52%), Gaps = 18/234 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA L + CGG LI FVLTAAHC +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ QEPTQQ V + + Y+ +N ND++L+QL A + +V ++LP V Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRKA 196 G C GWG+ + LQE+ +TV ++ +C P K Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 GDSGGPL+C+ + QGI S+ G + P T+V+ +V WI+ T++R Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSY---GRNNGMPPRACTKVSSFVHWIKKTMKRY 227 >1SGF-G nrPDB Length = 237 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 70/244 (28%), Positives = 117/244 (47%), Gaps = 31/244 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + + +S+P+ ++ + CGG L+ P++VLTAAHC D V LG Sbjct: 1 IVGGFKCEKNSQPWHVAVY---RYTQYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGK 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN------------NYDAENKLNDVLLIQLSSPANLSASVA 135 +N+ EP+ QH V++ + + + ND++L++LS PA+++ +V Sbjct: 54 NNLFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVT---------FFCRPH 185 + LP ++ + G+ CLA GWG L +N+ ++ Sbjct: 114 PITLPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDA 171 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C C GDSGGPLICDG++QGI S+ C P +T++ + WI+ Sbjct: 172 MLCAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKD 231 Query: 246 TLRR 249 T+ + Sbjct: 232 TMAK 235 >1PPF-E nrPDB Length = 218 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 120/221 (54%), Positives = 161/221 (72%), Gaps = 3/221 (1%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A+PH+ P+M SLQ+R G HFCG TLI P+FV++AAHC+ ++ R V VVLGA Sbjct: 1 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 HN+ +EPT+Q F+V ++F N YD N LND++++QL+ A ++A+V QLP Q + + Sbjct: 58 HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 117 Query: 148 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 207 +G QCLAMGWG +G + A VLQELNVTVVT CR N+CT V R+AG+CFGDSG PL Sbjct: 118 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPL 177 Query: 208 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 +C+G+I GI SFV GCA+ L+PD F VA +V+WI S ++ Sbjct: 178 VCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1BRU-P nrPDB Length = 241 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 82/241 (34%), Positives = 121/241 (50%), Gaps = 24/241 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNP-GSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG +A+P+S P+ SLQ + H CGGTL+ S+VLTAAHC+ R VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS--RTYRVVLG 58 Query: 87 AHNVRTQEPTQQHFSVAQVFLN---NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 H++ T EP V+++ ++ N + + ND+ L++L+SP +L+ + LP Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVP 192 +P+ C GWGR+ + +LQ+ + VV + + + IC Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG- 177 Query: 193 RRKAGICFGDSGGPLICDG-----IIQGIDSFV-IWGCATRLFPDFFTRVALYVDWIRST 246 C GDSGGPL C G + GI SF GC P FTRV+ Y+DWI S Sbjct: 178 DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSV 237 Query: 247 L 247 + Sbjct: 238 I 238 >2EEK-A nrPDB Length = 220 Score = 258 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 77/230 (33%), Positives = 120/230 (52%), Gaps = 21/230 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+E HS+ + SL N G HFCGG+L+ +V++AAHC + + + V LG Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCYKSV----LRVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H++R E T+Q+ S + V + NY + N ND++LI+L+ PA L+ V V LP + Sbjct: 53 HHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECA-- 110 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKAG 197 T C GWG + LQ L++ +++ C Sbjct: 111 ADATMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKD 170 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C+G++QG+ S+ +GCA R P + +V + W+R T+ Sbjct: 171 SCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTM 219 >3W94-A nrPDB Length = 235 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 76/239 (31%), Positives = 107/239 (44%), Gaps = 22/239 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 85 +VGG A+ + P+M SL R G H CG +LI ++LTAAHC+ L + VL Sbjct: 1 VVGGVNAEKGAWPWMVSLHWR---GRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 86 GAHNVRT-QEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H + Q V ++ +N NY+ K D+ ++ L P N + V V L +D Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPR 193 Q P G +C GWGR +LQE V +V + +C P Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPE 177 Query: 194 RKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C + G+ SF + GC P + RV+ + WI T R Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWIAETRR 235 >1NN6-A nrPDB Length = 228 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 91/233 (39%), Positives = 125/233 (53%), Gaps = 17/233 (7%) Query: 26 AEIVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVV 84 EI+GG E +PHSRPYMA L++ N S FCGG LI +FVLTAAHC R + V Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVT 56 Query: 85 LGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 LGAHN+ +E T Q V + F + Y+ +D++L++L A+L+ +V T+ P Q Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPH--------NICTFVPRRK 195 VP G C GWGR G P + LQE+ + ++ H +C PR+ Sbjct: 117 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKT 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 GDSGGPL+C G+ QGI S+ G + P FTR++ Y WI L+ Sbjct: 177 KSAFKGDSGGPLLCAGVAQGIVSY---GRSDAKPPAVFTRISHYRPWINQILQ 226 >6AOD-C nrPDB Length = 245 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 96/237 (40%), Gaps = 17/237 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 86 IVGG + P+ +L H CGG++I ++LTAAHC + +++ V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 + F V ++ +++ Y D+ L++L + + S + LP + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH---------NICTFVPRRK 195 T C GWG D LQ+ + +V C+ IC Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 196 AGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GD+GGPL C + GI S+ GCA R P +T V YVDWI + Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEYVDWILEKTQ 236 >2TLD-E nrPDB Length = 220 Score = 256 bits (655), Expect = 5e-69, Method: Composition-based stats. Identities = 78/231 (33%), Positives = 121/231 (52%), Gaps = 25/231 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG+ ++ PY SL N G HFCGG+LI+ +V++AAHC + + V LG Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGE 52 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 N+ E +Q S ++ ++ +Y++ ND++LI+L S A+L++ VA++ LP Sbjct: 53 DNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS- 111 Query: 147 PHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFF---------CRPHNICTFVPRRKA 196 GTQCL GWG + VL+ L +++ + C + Sbjct: 112 -AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE--GG 168 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGP++C G +QGI S+ GCA + P +T+V YV WI+ T+ Sbjct: 169 DSCQGDSGGPVVCSGKLQGIVSWGS-GCA-KNKPGVYTKVCNYVSWIKQTI 217 >1X7A-C nrPDB Length = 235 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 69/240 (28%), Positives = 113/240 (47%), Gaps = 26/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A+P P+ L + + FCGG++I+ +V+TAAHC+ P + VV G Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDA---FCGGSIINEKWVVTAAHCIE--PGVKITVVAGE 55 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDA--ENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 +N EPT+Q +V + ++Y+A +D+ L++L P L++ V + + ++ Sbjct: 56 YNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 145 P---VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVP 192 + G+ GWGRV A +LQ L V +V F + C Sbjct: 116 TNIFLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFH 174 Query: 193 RRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP + + + GI S+ CA + +T+V+ YV+WI+ + Sbjct: 175 EGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWIKEKTK 233 >4NFE-A nrPDB Length = 237 Score = 255 bits (653), Expect = 9e-69, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 122/242 (50%), Gaps = 31/242 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + HS+P+ ++ G CGG L+HP +VLTAAHCL+ + V LG Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWA---HCGGVLVHPQWVLTAAHCLK----KNSQVWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YD-----------AENKLNDVLLIQLSSPANLSASVA 135 HN+ E T Q V+ F + Y+ E+ +D++L++LS PA ++ V Sbjct: 54 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPP-AQVLQELNVTVVT---------FFCRPH 185 + LP Q+ + GT C A GWG + + + LQ +++ +++ Sbjct: 114 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF 171 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C + C GDSGGPL+C+G++QGI S+ CA P +T+V Y WI+ Sbjct: 172 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 231 Query: 246 TL 247 T+ Sbjct: 232 TI 233 >3T2N-A nrPDB Length = 372 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 76/256 (29%), Positives = 110/256 (42%), Gaps = 31/256 (12%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 IVGG + P+ SL+ G+H CGG+L+ +VLTAAHC + + L + Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 172 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNN-Y------DAENKLNDVLLIQLSSPANLSASVATVQ 138 A V P V V + Y ++E ND+ L+ LSSP L+ + V Sbjct: 173 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 232 Query: 139 LPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-----------FFCRPHNI 187 LP Q + G C GWG + A VLQE V +++ +P Sbjct: 233 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 292 Query: 188 CTFVPRRKAGICFGDSGGPLICD--------GIIQGIDSFVIWGCATRLFPDFFTRVALY 239 C P C GDSGGP +C+ + GI S+ GCA P +T+V+ + Sbjct: 293 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDF 351 Query: 240 VDWIRSTLR-RVEAKG 254 +WI ++ EA G Sbjct: 352 REWIFQAIKTHSEASG 367 >3LC3-A nrPDB Length = 235 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 26/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG +A+P P+ L + + FCGG++++ +++TAAHC+ + + VV G Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDA---FCGGSIVNEKWIVTAAHCVETGVK--ITVVAGE 55 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDA--ENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 HN+ E T+Q +V ++ +NY+A +D+ L++L P L++ V + + ++ Sbjct: 56 HNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 145 P---VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVP 192 + G+ GWGRV A VLQ L V +V F + C Sbjct: 116 TNIFLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFH 174 Query: 193 RRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP + + + GI S+ CA + +T+V+ YV+WI+ + Sbjct: 175 EGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWIKEKTK 233 >4H4F-A nrPDB Length = 249 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 81/241 (33%), Positives = 118/241 (48%), Gaps = 23/241 (9%) Query: 28 IVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG +A+PHS P+ SLQ + + H CGGTLI +FVLTAAHC+ + R V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 58 Query: 87 AHNVRTQ-EPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 +N+ + E V + ++ ++A ND+ LI+L+ LS ++ LP++D Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 145 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVPR 193 +P C GWGR+ + P A LQ+ VV + +C Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-D 177 Query: 194 RKAGICFGDSGGPLICD-----GIIQGIDSFVI-WGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL C + GI SF GC TR P +TRV+ Y+DWI + Sbjct: 178 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 237 Query: 248 R 248 + Sbjct: 238 Q 238 >3E0N-B nrPDB Length = 271 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 105/254 (41%), Gaps = 29/254 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVVLG 86 I GG A P+ S+ G H CGG+L+ +VL+AAHC + + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITYE---GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH + + + ++ + + +Y E D+ L+QLS P S + + LP Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 146 VPHGTQCLAMGWGRVGAHDP--PAQVLQELNVTVVT-----------------FFCRPHN 186 P+G C GWG V + LQ+L V +++ F + Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 187 ICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 +C C GDSGGPL C + GI S+ C R P +T + Y W Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGD-ACGARNRPGVYTLASSYASW 236 Query: 243 IRSTLRRVEAKGRP 256 I+S + ++ + P Sbjct: 237 IQSKVTELQPRVVP 250 >1KIG-H nrPDB Length = 241 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 63/238 (26%), Positives = 101/238 (42%), Gaps = 22/238 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + P+ A L N G FCGGT+++ +VLTAAHCL + V +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG--FCGGTILNEFYVLTAAHCLH--QAKRFTVRVGD 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD--- 143 N +E + V + + E D+ +++L +P +VA LP++D Sbjct: 57 RNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAE 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRR 194 + + G+GR + L+ L V V F P+ C + Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQ 176 Query: 195 KAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP + + GI S+ GCA + +T+V+ ++ WI ++ Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKFGVYTKVSNFLKWIDKIMK 233 >3TK9-A nrPDB Length = 226 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 85/234 (36%), Positives = 122/234 (52%), Gaps = 19/234 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHEA+PHSRPYMA +Q CGG L+ FVLTAAHC +NV LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC----QGSSINVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ QE TQQ V + + Y+ +N N+++L+QL A + +V ++LP V Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF----------FCRPHNICTFVPRRKA 196 G C GWG V + A LQE+ +TV + R IC P++ Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 GDSGGPL+C + QGI S+ P + +V+ ++ WI+ T++R+ Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYGN---KKGTPPGVYIKVSHFLPWIKRTMKRL 226 >4MPW-A nrPDB Length = 245 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 80/244 (32%), Positives = 116/244 (47%), Gaps = 33/244 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 85 IVGG EA P+ SL++ G HFCGG+LIHP +VLTAAHC+ + L + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 ++ Q+ Q V+++ ++ + D+ L++L P +S+ V TV LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 145 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVV-TFFC-----------------RP 184 P G C GWG V + PP L+++ V ++ C R Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 185 HNICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 +C RR C GDSGGPL+C + G+ S+ GCA P +TRV Y+ Sbjct: 178 DMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYL 234 Query: 241 DWIR 244 DWI Sbjct: 235 DWIH 238 >1C5M-D nrPDB Length = 255 Score = 250 bits (638), Expect = 5e-67, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 105/246 (42%), Gaps = 25/246 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + P+ A L N G FCGGT++ ++LTAAHCL + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEG--FCGGTILSEFYILTAAHCLY--QAKRFKVRVGD 56 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD--- 143 N +E + V V N + E D+ +++L +P +VA LP++D Sbjct: 57 RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAE 116 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRR 194 + + G+GR + L+ L V V F + C + Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTK 176 Query: 195 KAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 + C GDSGGP + + GI S+ GCA + +T+V ++ WI +++ Sbjct: 177 QEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRSMK-- 233 Query: 251 EAKGRP 256 +G P Sbjct: 234 -TRGLP 238 >3G01-A nrPDB Length = 227 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 83/234 (35%), Positives = 123/234 (52%), Gaps = 19/234 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSH-FCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG+E PHSRPYMA + G FCGG L+ FVLTAAHC R + V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AHN++ +E TQQ VA+ + +Y+ +++ ND++L++L A + +V + LP+++ Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV----------VTFFCRPHNICTFVPRRK 195 V G +C GWG+V + L E+ +TV + + R + IC + K Sbjct: 117 VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIK 176 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GDSGGPL+C GI S+ P FTRV +V WI+ T++ Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMKH 227 >4DGJ-A nrPDB Length = 235 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 22/236 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD--IPQRLVNVVL 85 IVGG +A+ + P++ L CG +L+ ++++AAHC+ + +L Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDR---LLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 86 GAHNVRT-QEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H P + ++ +N Y+ K ND+ ++ L N + + + LP+++ Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPR 193 Q P G C GWG V A +LQE +V +++ + + IC Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEE 177 Query: 194 RKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GDSGGPL+C + G+ SF + CA P + RV+ + +WI+S Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFTEWIQS 232 >1P57-B nrPDB Length = 255 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 110/254 (43%), Gaps = 31/254 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG + P+ SL+ G+H CGG+L+ +VLTAAHC + + L + A Sbjct: 1 IVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-Y------DAENKLNDVLLIQLSSPANLSASVATVQLP 140 V P V V + Y ++E ND+ L+ LSSP L+ + V LP Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 117 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-----------FFCRPHNICT 189 Q + G C GWG + A VLQE V +++ +P C Sbjct: 118 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 177 Query: 190 FVPRRKAGICFGDSGGPLICD--------GIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 P C GDSGGP +C+ + GI S+ GCA P +T+V+ + + Sbjct: 178 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFRE 236 Query: 242 WIRSTLR-RVEAKG 254 WI ++ EA G Sbjct: 237 WIFQAIKTHSEASG 250 >1NPM-A nrPDB Length = 225 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 73/234 (31%), Positives = 112/234 (47%), Gaps = 24/234 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G E PHS+P+ A+L CGG L+ +VLTAAHC ++ +V LG Sbjct: 1 ILEGRECIPHSQPWQAAL---FQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGD 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN----NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 H++++++ +Q VAQ + N + E+ +D++LI+L + ANL V VQL Sbjct: 54 HSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLC 113 Query: 144 QPVPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPR 193 V G +C+ GWG + L V + + +C Sbjct: 114 PKV--GQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-S 170 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 A C GDSGGPL+CDG++QGI S+ C P +T++ Y WI+ T+ Sbjct: 171 NGADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1LTO-A nrPDB Length = 245 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 79/244 (32%), Positives = 115/244 (47%), Gaps = 33/244 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR--LVNVVL 85 IVGG EA P+ SL++R HFCGG+LIHP +VLTAAHCL + + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 86 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 ++ Q+ Q V+++ ++ + D+ L++L P N+S+ V TV LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 145 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVVT------------------FFCRP 184 P G C GWG V + PP L+++ V ++ R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 185 HNICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 +C +R C GDSGGPL+C + G+ S+ GCA P +TRV Y+ Sbjct: 178 DMLCAGNSQR--DSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNRPGIYTRVTYYL 234 Query: 241 DWIR 244 DWI Sbjct: 235 DWIH 238 >3QUM-P nrPDB Length = 237 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 80/242 (33%), Positives = 124/242 (51%), Gaps = 31/242 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + HS+P+ + RG CGG L+HP +VLTAAHC+R+ ++LG Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRA---VCGGVLVHPQWVLTAAHCIRNKS----VILLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDA-----------ENKLNDVLLIQLSSPANLSASVA 135 H++ E T Q F V+ F + YD ++ +D++L++LS PA L+ +V Sbjct: 54 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVT---------FFCRPH 185 + LP Q+ + GT C A GWG + + + LQ +++ V++ Sbjct: 114 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF 171 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C C GDSGGPL+C+G++QGI S+ CA P +T+V Y WI+ Sbjct: 172 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 231 Query: 246 TL 247 T+ Sbjct: 232 TI 233 >1EKB-B nrPDB Length = 235 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 22/236 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI--PQRLVNVVL 85 IVGG +++ + P++ +L CG +L+ ++++AAHC+ VL Sbjct: 1 IVGGSDSREGAWPWVVALYFDD---QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 86 GAHNVRT-QEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H P + + Q+ +N Y+ K ND+ ++ L N + + + LP+++ Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPR 193 Q P G C GWG + A VLQE +V +++ + + +C Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 194 RKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GDSGGPL+C ++ G+ SF + CA P + RV + +WI+S Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFTEWIQS 232 >3DFJ-A nrPDB Length = 263 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 104/249 (41%), Gaps = 29/249 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVVLG 86 I GG A P+ S+ G H CGG+L+ +VL+AAHC + + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITYE---GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH + + + ++ + + +Y E D+ L+QLS P S + + LP + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 146 VPHGTQCLAMGWGRVGAHDP--PAQVLQELNVTVVT-----------------FFCRPHN 186 P+G C GWG V + LQ+L V +++ F + Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDM 177 Query: 187 ICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 +C C GDSGGPL C + GI S+ C R P +T + Y W Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGD-ACGARNRPGVYTLASSYASW 236 Query: 243 IRSTLRRVE 251 I+S + ++ Sbjct: 237 IQSKVTELQ 245 >5MS3-A nrPDB Length = 228 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 71/234 (30%), Positives = 110/234 (47%), Gaps = 24/234 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GGHE QPHS+P+ A+L CGG L+ ++VLTAAHC + V LG Sbjct: 1 VLGGHECQPHSQPWQAAL---FQGQQLLCGGVLVGGNWVLTAAHCKKP----KYTVRLGD 53 Query: 88 HNVRTQEPTQQHFSVAQVFLNN-YDA---ENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 H+++ ++ +Q V Q + Y++ E+ +D++L+QL A+L + V + L D Sbjct: 54 HSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--AD 111 Query: 144 QPVPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVTFF---------CRPHNICTFVPR 193 G +C GWG + L V + +C Sbjct: 112 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-S 170 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + A C GDSGGPL+CDG +QGI S+ C P +T + Y+DWI+ + Sbjct: 171 KGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >3BSQ-A nrPDB Length = 227 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 67/232 (28%), Positives = 109/232 (46%), Gaps = 22/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G S P+ +L + CGG L++ +VLTAAHC V LG+ Sbjct: 1 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGS 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + + Q ++ F + Y + +ND++L++L+S A LS+ V V+LP + + Sbjct: 54 DTLGDRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 109 Query: 147 PHGTQCLAMGWGRVGAHDPP-AQVLQELNVTVVT---------FFCRPHNICTFVPRRKA 196 P GT C GWG + D L ++V +++ +C +P K Sbjct: 110 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 169 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C G +QG+ S+ + C P +T+V + WI T++ Sbjct: 170 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2F91-A nrPDB Length = 237 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 71/236 (30%), Positives = 111/236 (47%), Gaps = 22/236 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGS-HFCGGTLIHPSFVLTAAHCLRDI---PQRLVNV 83 IVGG +A PY S Q S HFCG ++ + ++ +TA HC+ + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 V G ++ E ++Q +V+++ L+ N+D ND+ L++LS + +VA + LP+Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 143 DQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-CR---------PHNICTFVP 192 + GWG VLQ++ V +V+ CR IC VP Sbjct: 121 GHTATG--DVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 193 RRKAGICFGDSGGPLICDGI----IQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 C GDSGGPL + GI S+ +GCA +P +T V+ +VDWI+ Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSYHVDWIK 233 >3P8G-A nrPDB Length = 241 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 68/241 (28%), Positives = 100/241 (41%), Gaps = 25/241 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD------IPQRLV 81 +VGG +A P+ SL G H CG +LI P+++++AAHC D Sbjct: 1 VVGGTDADEGEWPWQVSLHALG--QGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 82 NVVLGAHNVRTQE-PTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQL 139 LG H+ + P Q + ++ ++ D+ L++L PA S+ V + L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF---------CRPHNICTF 190 P P G GWG A +LQ+ + V+ P +C Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVG 178 Query: 191 VPRRKAGICFGDSGGPLI---CDGIIQ--GIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 C GDSGGPL DG I G+ S+ GCA R P +TR+ L+ DWI+ Sbjct: 179 FLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD-GCAQRNKPGVYTRLPLFRDWIKE 237 Query: 246 T 246 Sbjct: 238 N 238 >1AE5-A nrPDB Length = 225 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 99/222 (44%), Positives = 139/222 (62%), Gaps = 7/222 (3%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG +A+P P++AS+Q N G HFCGG LIH FV+TAA C + + VVLGA Sbjct: 1 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 88 HNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 +++R +E ++Q FS++ + N YD + LND++L+QL ANL++SV + LP Q+ V Sbjct: 58 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 117 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHNICTFVPRRKAGICFGDSGG 205 GT+C GWG + ++ + +NVTV CRP+N+CT V R+ GIC GD G Sbjct: 118 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGT 177 Query: 206 PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 PL+C+G+ G+ SF + C PDFFTRVAL+ DWI L Sbjct: 178 PLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 217 >1SPJ-A nrPDB Length = 238 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 120/245 (48%), Gaps = 32/245 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG E + HS+P+ A+L CGG L+H +VLTAAHC+ D + LG Sbjct: 1 IVGGWECEQHSQPWQAALYHFST---FQCGGILVHRQWVLTAAHCISDN----YQLWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYD-----------AENKLNDVLLIQLSSPA-NLSASV 134 HN+ E T Q V++ F + ++ E+ +D++L++L+ PA ++ +V Sbjct: 54 HNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAV 113 Query: 135 ATVQLPQQDQPVPHGTQCLAMGWGRVG-AHDPPAQVLQELNVTVV-TFFC--------RP 184 V+LP ++ V G+ CLA GWG + + LQ +++ ++ C Sbjct: 114 KVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTD 171 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 +C C GDSGGPL+CDG++QG+ S+ C T P RV YV WI Sbjct: 172 FMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIE 231 Query: 245 STLRR 249 T+ Sbjct: 232 DTIAE 236 >1AO5-A nrPDB Length = 237 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 69/244 (28%), Positives = 117/244 (47%), Gaps = 31/244 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG + +S+P+ ++ + H CGG L+ ++VLTAAHC D V LG Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGK 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDA-----------ENKLNDVLLIQLSSPANLSASVA 135 + + +EP+ QH V++ F + ++ + +D++L++LS PA+++ V Sbjct: 54 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVV-TFFC--------RPH 185 + LP ++ G++CLA GWG + LQ + +T++ C Sbjct: 114 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV 171 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C C DSGGPLICDGI+QG S+ C P +T + + WI+ Sbjct: 172 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 231 Query: 246 TLRR 249 T+ + Sbjct: 232 TMMK 235 >3RP2-A nrPDB Length = 224 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 84/230 (36%), Positives = 120/230 (52%), Gaps = 17/230 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG E+ PHSRPYMA L + G CGG LI FVLTAAHC R + V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 87 AHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH+VR +E TQQ V + + +Y++ L+D++L++L L+ +V V LP Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FFCRPHNICTFVPRRKAG 197 + G C A GWG+ G DP + L+E+ + ++ ++ +C P Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 GDSGGPL+C G+ GI S+ P FTRV+ YV WI + + Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSYGH---PDAKPPAIFTRVSTYVPWINAVI 223 >1FDP-A nrPDB Length = 235 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 82/239 (34%), Positives = 120/239 (50%), Gaps = 17/239 (7%) Query: 21 GAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL 80 A I+GG EA+ H+RPYMAS+Q+ G+H CGG L+ +VL+AAHCL D Sbjct: 1 AAPPRGRILGGREAEAHARPYMASVQLN---GAHLCGGVLVAEQWVLSAAHCLEDAADGK 57 Query: 81 VNVVLGAHNVRTQEPTQQHFSVAQVFLNNYD-AENKLNDVLLIQLSSPANLSASVATVQL 139 V V+LGAH++ EP+++ + V + + + +D+LL+QLS A L +V + Sbjct: 58 VQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPW 117 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-----------CRPHNIC 188 + D+ V GT C GWG V LQ + + V+ +C Sbjct: 118 QRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMC 177 Query: 189 TFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + C GDSGGPL+C G+++G+ + C R P +TRVA Y WI S L Sbjct: 178 A--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1PYT-D nrPDB Length = 251 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 117/243 (48%), Gaps = 22/243 (9%) Query: 25 AAEIVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 +A +VGG +A PHS P+ SLQ R N H CGGTLI P+ VLTAAHC+ + V Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTL--TYRV 68 Query: 84 VLGAHNVRTQEP-TQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQ 141 LG +N+ ++ + V +F++ +++ ND+ LI+L+ L ++ LP Sbjct: 69 ALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPS 128 Query: 142 QDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTF 190 + +P C GWGR+ + P A LQ+ VV + + +C Sbjct: 129 EGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCAG 188 Query: 191 VPRRKAGICFGDSGGPLIC----DGIIQGIDSFVI-WGCATRLFPDFFTRVALYVDWIRS 245 C GDSGGPL C ++GI SF C T P FTRV+ Y+DWI Sbjct: 189 G-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQ 247 Query: 246 TLR 248 L+ Sbjct: 248 KLQ 250 >2RDL-A nrPDB Length = 226 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 87/232 (37%), Positives = 127/232 (54%), Gaps = 17/232 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHF-CGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG E +PH+RPYMA L++ C G LI +FV+TAAHC R + V+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC----AGRSITVLLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AHN + +E T Q V + F + YD LND++L++L ANL+ V T+ + + Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNS 116 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FFCRPHNICTFVPRRKAG 197 +P G C A+GWGR ++PP+ LQE+ + ++ F + +C P++ Sbjct: 117 IPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRN 176 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 + GDSGGPL+C GI QGI S+V+ P FTR++ Y WI LR Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVLR---NAKPPSVFTRISHYRPWINKILRE 225 >3K65-B nrPDB Length = 308 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 60/260 (23%), Positives = 104/260 (40%), Gaps = 38/260 (14%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQR 79 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 48 GRIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 106 Query: 80 LVNVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVAT 136 + V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + Sbjct: 107 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 166 Query: 137 VQLPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF------- 180 V LP ++ + G + GWG + VLQ +N+ +V Sbjct: 167 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 226 Query: 181 --FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLF 229 + C ++ C GD+GGP + GI S+ GC Sbjct: 227 RIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWG-EGCDRDGK 285 Query: 230 PDFFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 286 YGFYTHVFRLKKWIQKVIDQ 305 >1TON-A nrPDB Length = 235 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 118/244 (48%), Gaps = 33/244 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG++ + +S+P+ ++ + CGG LI PS+V+TAAHC + V+LG Sbjct: 1 IVGGYKCEKNSQPWQVAVINE-----YLCGGVLIDPSWVITAAHCYSNN----YQVLLGR 51 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAE-----------NKLNDVLLIQLSSPANLSASVA 135 +N+ EP Q V Q F + +Y + ND++L+ LS PA+++ V Sbjct: 52 NNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVK 111 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVT---------FFCRPH 185 + LP ++ V G+ CLA GWG + + LQ +N+ +++ Sbjct: 112 VIDLPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDV 169 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C C GDSGGPLICDG++QGI S CA P + ++ + WI+ Sbjct: 170 MLCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKK 229 Query: 246 TLRR 249 ++ Sbjct: 230 VMKE 233 >1BDA-A nrPDB Length = 265 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 115/253 (45%), Gaps = 32/253 (12%) Query: 27 EIVGGHEAQPHSRPYMASL---QMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI-PQRLVN 82 I GG A S P+ A++ R CGG LI ++L+AAHC ++ P + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 83 VVLGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSP----ANLSASVATV 137 V+LG +Q F V + ++ +D + ND+ L+QL S A S+ V TV Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 138 QLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTV-----------VTFFCRPH 185 LP D +P T+C G+G+ A P ++ L+E +V + + + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 186 NICTFVPRRKA------GICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTR 235 +C R C GDSGGPL+C + GI S+ + GC + P +T+ Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL-GCGQKDVPGVYTK 251 Query: 236 VALYVDWIRSTLR 248 V Y+DWIR +R Sbjct: 252 VTNYLDWIRDNMR 264 >3NXP-A nrPDB Length = 424 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 104/260 (40%), Gaps = 38/260 (14%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQR 79 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 164 GRIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 222 Query: 80 LVNVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVAT 136 + V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + Sbjct: 223 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 282 Query: 137 VQLPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF------- 180 V LP ++ + G + GWG + VLQ +N+ +V Sbjct: 283 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 342 Query: 181 --FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLF 229 + C ++ C GDSGGP + GI S+ GC Sbjct: 343 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-EGCDRDGK 401 Query: 230 PDFFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 402 YGFYTHVFRLKKWIQKVIDQ 421 >2PSX-A nrPDB Length = 227 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 21/233 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G + H++P+ A+L +R P +CG L+HP ++LTAAHC +++ V LG Sbjct: 1 IINGSDCDMHTQPWQAALLLR--PNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGH 54 Query: 88 HNVR--TQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 +++ + Q V + Y ND++LI+L+ + V + + Sbjct: 55 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV--SSHC 112 Query: 146 VPHGTQCLAMGWGRVGAHDPP-AQVLQELNVTVVTFF---------CRPHNICTFVPRRK 195 GT+CL GWG + +VLQ LN++V++ C + Sbjct: 113 PSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAG 171 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGP++C+G +QG+ S+ + CA P +T + + WI+ T++ Sbjct: 172 RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >2V35-A nrPDB Length = 240 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 77/240 (32%), Positives = 119/240 (49%), Gaps = 23/240 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMR-GNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG EAQ +S P SLQ R G+ +H CGGTLI ++V+TAAHC+ + VV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVD--RELTFRVVVG 58 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNY---DAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 HN+ + T+Q+ V ++ ++ Y D D+ L++L+ L++ V LP+ Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAG 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVP 192 + + + C GWG + AQ LQ+ + V + + +C Sbjct: 119 TILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGD 178 Query: 193 RRKAGICFGDSGGPLIC----DGIIQGIDSFVIW-GCATRLFPDFFTRVALYVDWIRSTL 247 ++G C GDSGGPL C + G+ SFV GC P FTRV+ Y+ WI + + Sbjct: 179 GVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 >1MKW-K nrPDB Length = 308 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 38/261 (14%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQR 79 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ Sbjct: 48 GRIVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVD 106 Query: 80 LVNVVLGAHNVRTQE-PTQQHFSVAQVFLN-NYDA-ENKLNDVLLIQLSSPANLSASVAT 136 + V +G H+ E ++ + +++++ Y+ EN D+ L++L P LS + Sbjct: 107 DLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHP 166 Query: 137 VQLPQQDQP---VPHGTQCLAMGWGR------VGAHDPPAQVLQELNVTVVTF------- 180 V LP + + G + GWG + VLQ +N+ +V Sbjct: 167 VCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 226 Query: 181 --FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLF 229 + C ++ C GDSGGP + GI S+ GC Sbjct: 227 RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG-EGCDRDGK 285 Query: 230 PDFFTRVALYVDWIRSTLRRV 250 F+T V WI+ + R+ Sbjct: 286 YGFYTHVFRLKKWIQKVIDRL 306 >4NZQ-A nrPDB Length = 557 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 104/260 (40%), Gaps = 38/260 (14%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQR 79 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 297 GRIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 355 Query: 80 LVNVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVAT 136 + V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + Sbjct: 356 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 415 Query: 137 VQLPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF------- 180 V LP ++ + G + GWG + VLQ +N+ +V Sbjct: 416 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 475 Query: 181 --FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLF 229 + C ++ C GDSGGP + GI S+ GC Sbjct: 476 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-EGCDRDGK 534 Query: 230 PDFFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 535 YGFYTHVFRLKKWIQKVIDQ 554 >5ZFH-A nrPDB Length = 224 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 67/232 (28%), Positives = 108/232 (46%), Gaps = 22/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G++ + S P+ +L CGG L+ +VLTAAHC V LG+ Sbjct: 1 IIDGYKCKEGSHPWQVALL---KGNQLHCGGVLVDKYWVLTAAHCKMGQ----YQVQLGS 53 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + Q Q + F + Y + +ND++L++L P +S+ V VQLP+ + Sbjct: 54 DKIGDQS--AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE-- 109 Query: 147 PHGTQCLAMGWGRVGAHDPP-AQVLQELNVTVVTF-FCRP--------HNICTFVPRRKA 196 P GT C GWG + D L +V +++ C+ +C +P K Sbjct: 110 PPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKT 169 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C+ +QG+ S+ + C P +T+V Y W+ T++ Sbjct: 170 NTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >6QHB-A nrPDB Length = 223 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 74/230 (32%), Positives = 112/230 (48%), Gaps = 20/230 (8%) Query: 29 VGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAH 88 V G S PY A+L G CGG LIHP +VLTAAHC + + V LG H Sbjct: 2 VHGGPCDKTSHPYQAALYT---SGHLLCGGVLIHPLWVLTAAHCKKPN----LQVFLGKH 54 Query: 89 NVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 N+ QE +Q+ SV + V +YDA + D++L++L+ PA LS + LP + Sbjct: 55 NLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSA 112 Query: 148 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF---------CRPHNICTFVPRRKAGI 198 T C +GWG+ D P +Q + +V+ + +C + Sbjct: 113 QTTSCHILGWGKTADGDFP-DTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 171 Query: 199 CFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPL+C ++G+ S+ C ++ P +T V Y +WI+ T++ Sbjct: 172 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1FIZ-A nrPDB Length = 263 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 113/249 (45%), Gaps = 30/249 (12%) Query: 28 IVGGHEAQPHSRPYMASLQ---MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNV 83 +VGG A+P + P+M SLQ N H CGG L++ +VLTAAHC ++ + + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 84 VLGAH------NVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATV 137 + GA+ N + P Q+ F + Y + ++ND+ LI+++ P + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 138 QLPQQDQPVPHG-TQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFF-----------CRP 184 LPQ P C GWG + P + LQE V ++ R Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDG------IIQGIDSFVIWGCATRLFPDFFTRVAL 238 N+C PR K C GDSGGPL+C ++ GI S+ + GCA P +T Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTWP 239 Query: 239 YVDWIRSTL 247 Y++WI S + Sbjct: 240 YLNWIASKI 248 >1YC0-A nrPDB Length = 283 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 113/245 (46%), Gaps = 28/245 (11%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-VNVVL 85 I+GG + P S P++A++ + G FC G+L+H +V++AAHC P R V+VVL Sbjct: 35 RIIGGSSSLPGSHPWLAAIYI----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNN-YDAEN-KLNDVLLIQLSSP----ANLSASVATVQL 139 G H Q F + + Y N +D++LI+L A S V + L Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 150 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAH-DPPAQVLQELNVTVV-TFFCR----------PHNI 187 P+ P G +C GWG + + + L+E V +V C P+ + Sbjct: 151 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 210 Query: 188 CTFVPRRKAGICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWI 243 C K+ C GDSGGPL C+ + GI S+ GC P +TRVA YVDWI Sbjct: 211 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVANYVDWI 269 Query: 244 RSTLR 248 +R Sbjct: 270 NDRIR 274 >1ORF-A nrPDB Length = 234 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 75/237 (31%), Positives = 117/237 (49%), Gaps = 22/237 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG+E PHSRPYM L + C G LI +VLTAAHC + V+LGA Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHC---NLNKRSQVILGA 54 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H++ +EPT+Q V + F YD + D+ L+QL+ A ++ V + LP++ V Sbjct: 55 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDV 114 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRP------------HNICTFVPR 193 GT C GWGR + L+E+ +T++ C + +C R Sbjct: 115 KPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 174 Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIWG-CATRLFPDFFTRVA-LYVDWIRSTLR 248 C GDSG PL+C+G+ +G+ SF + C P + ++ +++WI T++ Sbjct: 175 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1ELT-A nrPDB Length = 236 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 79/240 (32%), Positives = 118/240 (49%), Gaps = 24/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMR-GNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 +VGG AQP+S P+ SLQ + G+ H CGG+LI +V+TAAHC+ R VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS--ARTWRVVLG 58 Query: 87 AHNVRTQEPTQQHFSVAQVFLN---NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 HN+ T E +Q +V VF++ N D D+ L++L++ A+L+++V LP + Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVP 192 Q +P+ C GWG+ P + L++ + V + +C Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGG 178 Query: 193 RRKAGICFGDSGGPLICD----GIIQGIDSFV-IWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL C + G+ SFV GC P FTRV+ Y+ W+ + Sbjct: 179 ANSG--CNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >3S9B-A nrPDB Length = 234 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 109/232 (46%), Gaps = 20/232 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG E + P++ +L + H C G LI+ +VLTAAHC R R + + LG Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCDR----RNIRIKLGM 55 Query: 88 HNVRTQEPTQQHFSVAQVF--LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + LN D++LI+L P S +A V LP + + Sbjct: 56 HSKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRG 115 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRP---------HNICTFVPRRK 195 V G++C MGWG++ V N+ +V +C P +C + + Sbjct: 116 V--GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGG 172 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G + GI + C L P +T+V Y +WI+S + Sbjct: 173 RDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >4GSO-A nrPDB Length = 232 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 107/232 (46%), Gaps = 22/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + P++A L G +FCG TLI+ +V+TAAHC Q + LG Sbjct: 1 VLGGDECDINEHPFLAFLYSHG----YFCGLTLINQEWVVTAAHCDSTNFQ----MQLGV 52 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N +E D++LI+L P + S +A + LP Sbjct: 53 HSKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPS 112 Query: 146 VPHGTQCLAMGWGRVG-AHDPPAQVLQELNVTVVTFFC---------RPHNICTFVPRRK 195 V G+ C MGWG + ++ V N+ +V + +C V Sbjct: 113 V--GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGG 170 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S+ C P +T V Y DWI+ + Sbjct: 171 KDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >2BDH-A nrPDB Length = 223 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 73/232 (31%), Positives = 110/232 (47%), Gaps = 21/232 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+ G + PHS+P+ A+L M FC G L+HP +VL+AAHC Q + LG Sbjct: 1 IINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGL 53 Query: 88 HNVR-TQEPTQQHFSVA-QVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H++ QEP Q + V Y+ ND++LI+L + S ++ ++ + Q Sbjct: 54 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNV---------TVVTFFCRPHNICTFVPRRKA 196 G CL GWG + A+ VLQ +NV + P C + + Sbjct: 114 --AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 C GDSGGPLIC+G +QG+ SF C P +T + + +WI T++ Sbjct: 171 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >2AIQ-A nrPDB Length = 231 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 21/231 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + ++A + G+ CGGTLI+ +VLTA HC R + + LG Sbjct: 1 VIGGDECNINEHRFLALVYANGS----LCGGTLINQEWVLTARHCDRGN----MRIYLGM 52 Query: 88 HNVRTQEPTQ-QHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 HN++ + F + F LN + D++LI+L+ P SA +A + LP Sbjct: 53 HNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPS 112 Query: 146 VPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVTF-FCRP-------HNICTFVPRRKA 196 V G+ C MGWG + V N+ ++ + C+ +C + Sbjct: 113 V--GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGK 170 Query: 197 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S CA P +T+V Y DWI+S + Sbjct: 171 DTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >2CGA-A nrPDB Length = 245 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 80/245 (32%), Positives = 119/245 (48%), Gaps = 26/245 (10%) Query: 18 LLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP 77 +LSG + IV G EA P S P+ SLQ G HFCGG+LI+ ++V+TAAHC + Sbjct: 9 VLSGLS---RIVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVVTAAHC--GVT 61 Query: 78 QRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVAT 136 V VV G + + Q +A+VF N Y++ ND+ L++LS+ A+ S +V+ Sbjct: 62 TSDV-VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA 120 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVG-AHDPPAQVLQELNVTVVT---------FFCRPHN 186 V LP GT C+ GWG + LQ+ ++ +++ + Sbjct: 121 VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM 180 Query: 187 ICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 IC C GDSGGPL+C + GI S+ C+T P + RV V+W Sbjct: 181 ICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPGVYARVTALVNW 237 Query: 243 IRSTL 247 ++ TL Sbjct: 238 VQQTL 242 >5LHN-A nrPDB Length = 247 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 76/247 (30%), Positives = 121/247 (48%), Gaps = 28/247 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMR---GNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR-LVNV 83 IVGG + ++P+ A++ + G+P S CGG+LI P +V +AAHC +P++ V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNNY---DAENKLNDVLLIQLSSP----ANLSASVAT 136 LG + P + F V Q+ L+ Y D+ ND+ L+++ + A S S+ T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTF-----------FCRP 184 + LP + P G+ C G+G+ D + L+ V +V+ Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 185 HNICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 +C P K C GDSGGPLIC+ + GI S+ GCA + P +TRV+ ++ Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKNKPGVYTRVSHFL 239 Query: 241 DWIRSTL 247 DWI+S + Sbjct: 240 DWIQSHI 246 >1MZD-A nrPDB Length = 240 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 79/238 (33%), Positives = 118/238 (49%), Gaps = 22/238 (9%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC-LRDIPQRLVNVVL 85 EI+GG E PHSRP+MAS+Q G H CGG LI P +VLTAAHC R + VVL Sbjct: 2 EIIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 86 GAHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 GAH++ E ++Q + + + ++ + ND++L++L + A L+ V + + + Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 117 Query: 145 PVPHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF-------------FCRPHNICTF 190 + GT+C GWG P+ L+E+ VTV++ F +C Sbjct: 118 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 177 Query: 191 VPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVA-LYVDWIRSTL 247 + + C GD+GGPLIC G+ I S C P +T + Y WI+S L Sbjct: 178 DAKGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 234 >5FCR-A nrPDB Length = 234 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 118/232 (50%), Gaps = 18/232 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-VNVVLG 86 I+GG EA H+RPYMAS+Q+ G+H CGGTL+ +VL+AAHC+ + V V+LG Sbjct: 1 ILGGQEAAAHARPYMASVQVN---GTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 AH++ EP ++ + V V + ++ +D++L +LS A+L V + L +D+ Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVPRR 194 V GT C GWG V VL +L V+++ + +C Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESN 175 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 + C GDSG PL+C ++G+ ++ C P +TRV+ Y WI + Sbjct: 176 RRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI 227 >4Q7Y-A nrPDB Length = 250 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 87/241 (36%), Positives = 119/241 (49%), Gaps = 15/241 (6%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GGHE PHSRPYMAS++ G H CGG L+ +V++AAHC R VVLGA Sbjct: 1 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 57 Query: 88 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H + T EPTQQ F + + +Y ND+ L++L+ A L +V ++LP + Sbjct: 58 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARP 117 Query: 147 P-HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPH--------NICTFVPRR-K 195 P GT+C GWG V + L E V V+ C +CT + Sbjct: 118 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 177 Query: 196 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGR 255 G C DSGGPL+C G+ SF C PD +T+V+ +V WI +RR + Sbjct: 178 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 237 Query: 256 P 256 P Sbjct: 238 P 238 >1FIW-A nrPDB Length = 290 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 111/249 (44%), Gaps = 30/249 (12%) Query: 28 IVGGHEAQPHSRPYMASLQ---MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNV 83 I+GG +A + P+M SLQ N H CGG+L++ ++LTAAHC R + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 84 VLGA------HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATV 137 + GA N + P Q+ + + Y A ++ ND+ L++++ P + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 138 QLPQQDQPVPHG-TQCLAMGWGRVGAH-DPPAQVLQELNVTVVTF-----------FCRP 184 LPQ P C GWG + + + +LQE V ++ R Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 185 HNICTFVPRRKAGICFGDSGGPLICDG------IIQGIDSFVIWGCATRLFPDFFTRVAL 238 N+C P K C GDSGGPL+C ++ GI S+ + GCA P +T Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTWS 239 Query: 239 YVDWIRSTL 247 Y++WI S + Sbjct: 240 YLNWIASKI 248 >2R0L-A nrPDB Length = 248 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 78/244 (31%), Positives = 113/244 (46%), Gaps = 28/244 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL-VNVVLG 86 I+GG + P S P++A++ + G FC G+L+H +V++AAHC P R V+VVLG Sbjct: 1 IIGGSSSLPGSHPWLAAIYI----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAEN-KLNDVLLIQLSSP----ANLSASVATVQLP 140 H Q F + + Y N +D++LI+L A S V + LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 141 QQDQPVPHGTQCLAMGWGRVGAH-DPPAQVLQELNVTVV-TFFCR----------PHNIC 188 + P G +C GWG + + + L+E V +V C P+ +C Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 189 TFVPRRKAGICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 K+ C GDSGGPL C+ + GI S+ GC P +TRVA YVDWI Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVANYVDWIN 235 Query: 245 STLR 248 +R Sbjct: 236 DRIR 239 >2OCV-B nrPDB Length = 259 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 60/258 (23%), Positives = 106/258 (41%), Gaps = 38/258 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHC+ ++ + + Sbjct: 1 IVEGWDAEKGIAPWQVML-FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 82 NVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF--------- 180 LP + + G + GWG + ++ VLQ +N+ +V Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRI 179 Query: 181 FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPD 231 + C ++ C GDSGGP + GI S+ GC + Sbjct: 180 RITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-EGCDRKGKYG 238 Query: 232 FFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 239 FYTHVFRLKAWIQKVIDQ 256 >1A5I-A nrPDB Length = 265 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 115/249 (46%), Gaps = 32/249 (12%) Query: 30 GGHEAQPHSRPYMASL--QMRGNPGSHF-CGGTLIHPSFVLTAAHCLR-DIPQRLVNVVL 85 GG S P+ A++ Q R + G F CGG LI +VLTAAHC + + VVL Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 86 GAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSP----ANLSASVATVQLP 140 G +Q F V + ++ +D + ND+ L+QL S A S SV + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 141 QQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVV-TFFCRP----------HNIC 188 + + +P T+C G+G+ + P ++ L+E +V + + C P + +C Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 189 TFVPRRKA------GICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVAL 238 R C GDSGGPL+C + GI S+ + GC + P +T+V Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKVTN 254 Query: 239 YVDWIRSTL 247 Y+ WIR + Sbjct: 255 YLGWIRDNM 263 >4Z6A-H nrPDB Length = 249 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 71/246 (28%), Positives = 110/246 (44%), Gaps = 22/246 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 86 IVGG P+ L + G+ CGGTLI+ +V++AAHC I R + VLG Sbjct: 1 IVGGKVCPKGECPWQVLLLVN---GAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQ--- 142 H++ + +Q VAQV + + Y +D+ L++L P L+ V + LP++ Sbjct: 58 EHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFS 117 Query: 143 DQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVT-VVTFFC--------RPHNICTFVPR 193 ++ + L GWG++ A L LNV ++T C + C Sbjct: 118 ERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSD 177 Query: 194 RKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 C GDSGGP + GI S+ GCAT +TRV+ Y++W++ +R Sbjct: 178 GSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQYIEWLQKLMRS 236 Query: 250 VEAKGR 255 G Sbjct: 237 EPRPGV 242 >1KYN-A nrPDB Length = 235 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 86/234 (36%), Positives = 128/234 (54%), Gaps = 18/234 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E++PHSRPYMA LQ++ G CGG L+ FVLTAAHC +NV LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN----INVTLGA 56 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN++ +E TQQH + + + Y+ ND++L+QLS + +V V LP+ + + Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRRKAG 197 GT C GWGRV + L+E+ + V + IC R + Sbjct: 117 RPGTLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKA 175 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVE 251 GDSGGPL+C+ + GI S+ G ++ + P+ FTRV+ ++ WIR+T+R + Sbjct: 176 AFKGDSGGPLLCNNVAHGIVSY---GKSSGVPPEVFTRVSSFLPWIRTTMRSFK 226 >1ETT-H nrPDB Length = 259 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 104/259 (40%), Gaps = 38/259 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 82 NVVLGAHNVRTQE-PTQQHFSVAQVFLN-NYDA-ENKLNDVLLIQLSSPANLSASVATVQ 138 V +G H+ E ++ + +++++ Y+ EN D+ L++L P LS + V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGR------VGAHDPPAQVLQELNVTVVTF--------- 180 LP + + G + GWG + VLQ +N+ +V Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 179 Query: 181 FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPD 231 + C ++ C GDSGGP + GI S+ GC Sbjct: 180 RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG-EGCDRDGKYG 238 Query: 232 FFTRVALYVDWIRSTLRRV 250 F+T V WI+ + R+ Sbjct: 239 FYTHVFRLKKWIQKVIDRL 257 >1SC8-U nrPDB Length = 262 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 117/249 (46%), Gaps = 27/249 (10%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGS--HFCGGTLIHPSFVLTAAHCLRDIPQR-LVNV 83 +I+GG ++P+ A++ R GS + CGG+LI P +V++A HC D P++ V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNN-YDAEN--KLNDVLLIQLSSP----ANLSASVAT 136 LG + + + F V + L+ Y A+ ND+ L+++ S A S ++ T Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTF-----------FCRP 184 + LP GT C G+G+ + D + L+ V +++ Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 194 Query: 185 HNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 +C P+ K C GDSGGPL+C + GI S+ GCA + P +TRV+ ++ Sbjct: 195 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG-RGCALKDKPGVYTRVSHFL 253 Query: 241 DWIRSTLRR 249 WIRS + Sbjct: 254 PWIRSHTKE 262 >1VR1-H nrPDB Length = 261 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 103/261 (39%), Gaps = 40/261 (15%) Query: 28 IVGGHEAQPHSRPYMASL---QMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQ 78 IV G +A+ P+ L R CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 79 RLVNVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVA 135 + V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 136 TVQLPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF------ 180 V LP ++ + G + GWG + VLQ +N+ +V Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 181 ---FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRL 228 + C + ++ C GDSGGP + GI S+ GC Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-EGCDRDG 239 Query: 229 FPDFFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQ 260 >1SGF-A nrPDB Length = 240 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 112/237 (47%), Gaps = 32/237 (13%) Query: 33 EAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRT 92 + + +S+P+ ++ CGG L+ ++VLTAAHC D V LG +N Sbjct: 10 DCE-NSQPWHVAVYRFNKYQ---CGGVLLDRNWVLTAAHCYND----KYQVWLGKNNFLE 61 Query: 93 QEPTQQHFSVAQVFLN-NYDA-----------ENKLNDVLLIQLSSPANLSASVATVQLP 140 EP+ QH V++ + +++ ++ ND++L++LS PA+++ V + LP Sbjct: 62 DEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLP 121 Query: 141 QQDQPVPHGTQCLAMGWGRVGA-HDPPAQVLQELNVTVV---------TFFCRPHNICTF 190 ++ + G+ CLA GWG LQ +N+ ++ +C Sbjct: 122 TEEPKL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAG 179 Query: 191 VPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + C DSGGPLICDGI+QGI S+ C P +T++ + WIR T+ Sbjct: 180 EMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 236 >4E7N-A nrPDB Length = 238 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 70/235 (29%), Positives = 108/235 (45%), Gaps = 22/235 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E + ++ +L + FCGGTLI+ +VLTAAHC R + + LG Sbjct: 1 IIGGDECNINEHRFLVALY-TSRSRTLFCGGTLINQEWVLTAAHCDR----KNFRIKLGM 55 Query: 88 HNVRTQEPTQQHFSVAQVF--LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + F L++ + D++LI+L SP S +A P Sbjct: 56 HSKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSP 113 Query: 146 VPHGTQCLAMGWGRVGAH-DPPAQVLQELNVTVVTF-FCR-----------PHNICTFVP 192 G+ C MGWGR+ V +N+ ++ + CR +C + Sbjct: 114 PSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGIL 173 Query: 193 RRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S+ CA P +T+V ++DWI + + Sbjct: 174 EGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >2OQ5-A nrPDB Length = 232 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 98/237 (41%), Gaps = 26/237 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 86 IVGG E + P+ ASLQ GSH CG TLI+ +++++AAHC G Sbjct: 1 IVGGTEVEEGEWPWQASLQWD---GSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 T +P++ + ++ ++ Y + D+ L +LSSP + +V V LP Sbjct: 58 V----TIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYE 113 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-----------CRPHNICTFVPRR 194 G G+G + L++ VT++ P +C Sbjct: 114 FQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEG 173 Query: 195 KAGICFGDSGGPLICD-----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 K C GDSGGPL+ + GI S+ CA P +TRV DWI S Sbjct: 174 KTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWITSK 229 >4XDE-A nrPDB Length = 257 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 105/245 (42%), Gaps = 31/245 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 86 +VGG A + PY+A+L G FC G+LI P +VLTAAHCL+D P + VVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 87 AHNVR-TQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPAN-----LSASVATVQLP 140 + EP Q + + + +D+ L++L A+ LS V V LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 141 QQDQPVPHGTQCLAMGWGRVGAH-DPPAQVLQELNVTVVTFF-----------CRPHNIC 188 T C GWG + A LQE V ++ P +C Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLC 178 Query: 189 TFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C GDSGGPL+C+ +QGI S+ GC R P +T VA Y+ Sbjct: 179 AGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVYTDVAYYLA 237 Query: 242 WIRST 246 WIR Sbjct: 238 WIREH 242 >1FON-A nrPDB Length = 240 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 27/241 (11%) Query: 30 GGHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAH 88 G +A P+S + SLQ + H CGG+LI P +V+TA HC+ R VVLG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS--RTYQVVLGEY 58 Query: 89 NVRTQEPTQQHFSVA--QVFLN---NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 + E ++Q + +F++ N + ND+ L++LS A L V LP Sbjct: 59 DRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-----------FCRPHNICTFVP 192 +P+ C GWGR+ P LQ+ + V + + +C Sbjct: 119 DILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGD 178 Query: 193 RRKAGICFGDSGGPLIC-----DGIIQGIDSFVI-WGCATRLFPDFFTRVALYVDWIRST 246 R C GDSGGPL C + G+ SFV +GC T P FTRV+ ++DWI T Sbjct: 179 TRSG--CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDET 236 Query: 247 L 247 + Sbjct: 237 I 237 >1GVZ-A nrPDB Length = 237 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 31/244 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E + HS+P+ ++ + G CGG L+HP +VLTAAHC+ D + LG Sbjct: 1 IIGGWECEKHSKPWQVAVYHQ---GHFQCGGVLVHPQWVLTAAHCMSD----DYQIWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYD-----------AENKLNDVLLIQLSSPANLSASVA 135 HN+ E T Q V+ FL +D ++ +D++L++L+ PA ++ +V Sbjct: 54 HNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVK 113 Query: 136 TVQLPQQDQPVPHGTQCLAMGWGRVGA-HDPPAQVLQELNVTVVT---------FFCRPH 185 + LP Q+ + G+ C GWG + + + LQ + + + + Sbjct: 114 ILDLPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEF 171 Query: 186 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 +C IC GDSGG LICDG+ QGI S+ CA FT+V + WI+ Sbjct: 172 VLCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKE 231 Query: 246 TLRR 249 T+ + Sbjct: 232 TIEK 235 >5TO3-B nrPDB Length = 409 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 61/258 (23%), Positives = 103/258 (39%), Gaps = 38/258 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 82 NVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGRVGA------HDPPAQVLQELNVTVVTF--------- 180 LP ++ + G + GWG + VLQ +N+ +V Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 179 Query: 181 FCRPHNICTFV---PRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPD 231 + C ++ C GDSGGP + GI S GC Sbjct: 180 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA-GCDRDGKYG 238 Query: 232 FFTRVALYVDWIRSTLRR 249 F+T V WI+ + + Sbjct: 239 FYTHVFRLKKWIQKVIDQ 256 >2ZKS-A nrPDB Length = 240 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 85/237 (35%), Positives = 112/237 (47%), Gaps = 20/237 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E PHSRPYMASLQ GSH CGG L+HP +VLTAAHCL + + +VLG Sbjct: 1 IIGGREVIPHSRPYMASLQRN---GSHLCGGVLVHPKWVLTAAHCLAQRMAQ-LRLVLGL 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDA-ENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 H + P A + Y ND+ L+QL S ++ + LP + Q V Sbjct: 57 HTL--DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 114 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-----------CRPHNICTFVPRRK 195 GT+C GWG ++VL+EL++ V+ P +C + Sbjct: 115 AAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKD 174 Query: 196 AGICFGDSGGPLICDG--IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 C GDSGGPL+C ++ G+ SF C P T VA YV WIR R Sbjct: 175 QAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >3F6U-H nrPDB Length = 240 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 65/243 (26%), Positives = 110/243 (45%), Gaps = 28/243 (11%) Query: 29 VGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAH 88 + G + P+ L + CG LIHPS+VLTAAHC+ + + + V LG + Sbjct: 2 IDGKMTRRGDSPWQVVLL--DSKKKLACGAVLIHPSWVLTAAHCMDESKK--LLVRLGEY 57 Query: 89 NVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD---- 143 ++R E + + +VF++ NY ND+ L+ L+ PA LS ++ + LP Sbjct: 58 DLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAER 117 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQ-----VLQELNVTVV---------TFFCRPHNICT 189 + G + L GWG + + A+ VL + + VV + + +C Sbjct: 118 ELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCA 177 Query: 190 FVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 245 + + C GDSGGP++ + G+ S+ GC +T+V+ Y+DWI Sbjct: 178 GILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVSRYLDWIHG 236 Query: 246 TLR 248 +R Sbjct: 237 HIR 239 >4BXW-A nrPDB Length = 423 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 106/249 (42%), Gaps = 32/249 (12%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 IV G + + P+ A+L FCGGT++ P +VLTAAHC+ + ++VV+G Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEG--VFCGGTILSPIYVLTAAHCINET--ETISVVVG 224 Query: 87 AHNVRTQEPTQQHFSVAQVFLN----------NYDAENKLNDVLLIQLSSPANLSASVAT 136 + E T SV +++++ +D D+ +IQ+ +P S +V Sbjct: 225 EIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVP 283 Query: 137 VQLPQQD---QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF---------CRP 184 LP D Q + + G+GR+ P ++ L+ L V V P Sbjct: 284 ACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITP 343 Query: 185 HNICTFVPRRKAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240 + C C GDSGGP I GI S GCA +T+++ ++ Sbjct: 344 NMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG-EGCARNGKYGNYTKLSKFI 402 Query: 241 DWIRSTLRR 249 WI+ +R+ Sbjct: 403 PWIKRIMRQ 411 >1Q3X-A nrPDB Length = 328 Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 99/254 (38%), Gaps = 31/254 (12%) Query: 19 LSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ 78 LS I GG +A+P P+ + G G L++ ++VLTAAH + + Sbjct: 78 LSARTTGGRIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 132 Query: 79 RLVNVVLGAHNVRTQEPT-QQHFSVAQVFLNNYDAE-NKLNDVLLIQLSSPANLSASVAT 136 + + ++ P Q +S A Y + ND+ LI+L++ +++++ Sbjct: 133 DASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 192 Query: 137 VQLPQQDQPVPHGTQ--CLAMGWGRVGAHDPPAQVLQELNVTVVTF-------------- 180 + LP+++ T A GWG A+ L +++ +V Sbjct: 193 ICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPR 251 Query: 181 -FCRPHNICTFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFF 233 + +C + C GDSGG L+ + GI S+ C + Sbjct: 252 GSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVY 311 Query: 234 TRVALYVDWIRSTL 247 T+V Y+ WI + + Sbjct: 312 TKVINYIPWIENII 325 >1OP0-A nrPDB Length = 234 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 66/233 (28%), Positives = 104/233 (44%), Gaps = 22/233 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG+E + ++ + N FCGGTLI+P +V+TAAHC + LG Sbjct: 1 VIGGNECDINEHRFLVAF---FNTTGFFCGGTLINPEWVVTAAHCDST----DFQMQLGV 53 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N + E D++LI+L P + S +A + P Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSP 111 Query: 146 VPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVTF-FCRP---------HNICTFVPRR 194 G+ C MGWG + V N+ ++ C+ +C + + Sbjct: 112 PSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQG 171 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI S+ C P +T V Y DWI+ + Sbjct: 172 GKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >1ZJK-A nrPDB Length = 403 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 100/254 (39%), Gaps = 31/254 (12%) Query: 19 LSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ 78 LS +I GG +A+P P+ + G G L++ ++VLTAAH + + Sbjct: 153 LSARTTGGQIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 207 Query: 79 RLVNVVLGAHNVRTQEPT-QQHFSVAQVFLNNYDAE-NKLNDVLLIQLSSPANLSASVAT 136 + + ++ P Q +S A Y + ND+ LI+L++ +++++ Sbjct: 208 DASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 267 Query: 137 VQLPQQDQPVPHGTQ--CLAMGWGRVGAHDPPAQVLQELNVTVVTF-------------- 180 + LP+++ T A GWG A+ L +++ +V Sbjct: 268 ICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPR 326 Query: 181 -FCRPHNICTFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFF 233 + +C + C GDSGG L+ + GI S+ C + Sbjct: 327 GSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVY 386 Query: 234 TRVALYVDWIRSTL 247 T+V Y+ WI + + Sbjct: 387 TKVINYIPWIENII 400 >1BQY-A nrPDB Length = 234 Score = 219 bits (559), Expect = 7e-58, Method: Composition-based stats. Identities = 67/233 (28%), Positives = 103/233 (44%), Gaps = 22/233 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 + GG E + SL + N CGGTLI+ +V+TAAHC + Q ++ G Sbjct: 1 VFGGDECNINEHR---SLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQ----LLFGV 53 Query: 88 HNVRTQEPTQQHFSVAQVF--LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + F N + D++LI+L S + S +A + P Sbjct: 54 HSKKILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSP 111 Query: 146 VPHGTQCLAMGWGRV-GAHDPPAQVLQELNVTVVTF-FCRP---------HNICTFVPRR 194 G+ C MGWG+ + V N+ ++ CR +C + + Sbjct: 112 PSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQG 171 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C DSGGPLIC+GI QGI S+ C P +T+V Y+DWI+S + Sbjct: 172 GRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >1AZZ-A nrPDB Length = 226 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 86/227 (37%), Positives = 119/227 (52%), Gaps = 18/227 (7%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG EA P+S P+ A+L + +FCGG+LI P ++LTAAHC+ V+VVLGA Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDG--AGFVDVVLGA 55 Query: 88 HNVRTQEPTQQHFSVAQV-FLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 HN+R E TQ NY++ ND+ +I+L P L+A++ATV LP D V Sbjct: 56 HNIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV 115 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVVTF--------FCRPHNICTFVPRRKAG 197 GT GWG + VL++++V +++ NIC G Sbjct: 116 --GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICI-DSTGGKG 172 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 C GDSGGPL +G+ GI SF +PD FTRV ++DWI+ Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >2XXL-A nrPDB Length = 408 Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 103/259 (39%), Gaps = 38/259 (14%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHF-CGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 + + G+E + SRP+MA L+ + S F CGG +I ++LTAAHC+ + L + Sbjct: 116 SQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEI 175 Query: 84 VLGAHNVRTQEPTQQHFSVAQ-------------VFLNNYDAENKLNDVLLIQLSSPANL 130 LG H + T+E +Q + + YDA + ++D+ L++L+ Sbjct: 176 RLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235 Query: 131 SASVATVQLPQQDQPVPHG---TQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRP-- 184 + + LP D+ + GWG + + VL + NV + C Sbjct: 236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSACSQAY 294 Query: 185 ------HNICTFVPRRKAGICFGDSGGPLICDG----------IIQGIDSFVIWGCATRL 228 +C C GDSGGPL + GI S + C Sbjct: 295 RRAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQIS 353 Query: 229 FPDFFTRVALYVDWIRSTL 247 P +T V YV WI T+ Sbjct: 354 LPGLYTNVGEYVQWITDTM 372 >4FXG-H nrPDB Length = 242 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 51/245 (20%), Positives = 97/245 (39%), Gaps = 31/245 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I GG +A+P P+ + G G L++ ++VLTAAH + + + + Sbjct: 1 IYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 88 HNVRTQEPT-QQHFSVAQVFLNNYDAE-NKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 ++ P Q +S A Y + ND+ LI+L++ +++++ + LP+++ Sbjct: 56 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 115 Query: 146 VPHGTQ--CLAMGWGRVGAHDPPAQVLQELNVTVVTF---------------FCRPHNIC 188 T A GWG A+ L +++ +V + +C Sbjct: 116 SFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLC 174 Query: 189 TFVPRRKAGICFGDSGGPLIC------DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 + C GD+GG L+ + GI S+ C +T+V Y+ W Sbjct: 175 AGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPW 234 Query: 243 IRSTL 247 I + + Sbjct: 235 IENII 239 >4IW4-E nrPDB Length = 279 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 65/275 (23%), Positives = 107/275 (38%), Gaps = 46/275 (16%) Query: 28 IVGGHEAQPHSRPYMASLQMRGN---PGSHFCG-GTLIHPSFVLTAAHCLRDI------- 76 I+GG A+P P+ A + + P + G G L+ S++LTAAH LR Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 77 --PQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASV 134 + V V LG H+VR + + V +++ +N +D+ L+QL P L V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 135 ATVQLPQQDQP-VPHGTQCLAMGWGRVGAH-----------DPPAQVLQELNVTVV---- 178 V LP+ + L GWG + + VLQ + + VV Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 179 ----------TFFCRPHNICTFVPRRKAGICFGDSGGPLI------CDGIIQGIDSFVI- 221 + + C C GDSGG + ++QG+ S+ Sbjct: 181 CKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGP 240 Query: 222 WGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP 256 C ++ +T+V+ YVDW+ + ++ P Sbjct: 241 EECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEP 275 >5XRF-A nrPDB Length = 242 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 73/235 (31%), Positives = 110/235 (46%), Gaps = 24/235 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG+E + ++A+ P + C GTLIH +VL AAHC + R +N+ LG Sbjct: 7 VIGGNECDTNEHRFLAAF-FTSRPWTFQCAGTLIHEEWVLAAAHCYK----RGLNIYLGM 61 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENK----LNDVLLIQLSSPANLSASVATVQLPQQD 143 HN Q +Q + + Y + K DV+L++L+ P + S +A + Sbjct: 62 HNQSIQFDDEQRRYA--IEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LPS 117 Query: 144 QPVPHGTQCLAMGWGRVGA-HDPPAQVLQELNVTVVTFF-CRPHN---------ICTFVP 192 P G+ C MGWG + + D V N+ ++ + C H +C V Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVL 177 Query: 193 RRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C DSGGPLICDG QGI F + CA P +TRV+ Y DWI++ + Sbjct: 178 EGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >4KKD-A nrPDB Length = 433 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 64/276 (23%), Positives = 106/276 (38%), Gaps = 46/276 (16%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGN---PGSHFCG-GTLIHPSFVLTAAHCLRDI------ 76 I+GG A+P P+ A + + P + G G L+ S++LTAAH LR Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 77 ---PQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSAS 133 + V V LG H+VR + + V +++ +N +D+ L+QL P L Sbjct: 214 IPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 134 VATVQLPQQDQP-VPHGTQCLAMGWGRVGAH-----------DPPAQVLQELNVTVV--- 178 V V LP+ + L GWG + + VLQ + + VV Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 179 -----------TFFCRPHNICTFVPRRKAGICFGDSGGPLI------CDGIIQGIDSFVI 221 + + C C GDSG + ++QG+ S+ Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWGG 393 Query: 222 -WGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP 256 C ++ +T+V+ YVDW+ + ++ P Sbjct: 394 PEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEP 429 >3S69-A nrPDB Length = 234 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 70/233 (30%), Positives = 100/233 (42%), Gaps = 22/233 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG E + SL N FC GTLI+ +VLTAAHC Q + LG Sbjct: 1 VIGGDECNINEHR---SLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQ----MKLGV 53 Query: 88 HNVRTQEPTQQHFSVAQVFL--NNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 H+ + +Q + + F+ N + E D++LI+L S + S + V L P Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSP 111 Query: 146 VPHGTQCLAMGWGR-VGAHDPPAQVLQELNVTVVTF-FCRP---------HNICTFVPRR 194 G+ C MGWG V + ++ C+ +C + Sbjct: 112 PSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEG 171 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPLIC+G QGI SF C L P +T+V Y WI+S + Sbjct: 172 GKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >4LK4-A nrPDB Length = 357 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 67/251 (26%), Positives = 115/251 (45%), Gaps = 21/251 (8%) Query: 18 LLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNP--GSHFCGGTLIHPSFVLTAAHCLRD 75 + S A ++ I+ G A P + +L RG FCGG+ + +VLTAAHC Sbjct: 1 MESTADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDS 60 Query: 76 IPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASV 134 V+V++GA+++ + + +++ + +Y N LND+ +++L+ ++L A Sbjct: 61 RSAASVDVIIGAYDLNNSSQGE-RIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPA-- 117 Query: 135 ATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPA--QVLQELNVTVVT-FFCR-------- 183 T+ P +P T GWG PP +LQE++V +V+ C+ Sbjct: 118 ITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGIS 177 Query: 184 --PHNICTFVPRRKAGICFGDSGGPLICD-GIIQ-GIDSFVIWGCATRLFPDFFTRVALY 239 P++ R C GD+GGP++ G Q GI S+ CA +T V+ + Sbjct: 178 SDPNSTNFCAARLTKDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYF 237 Query: 240 VDWIRSTLRRV 250 DWI ++ Sbjct: 238 RDWITKHTNQL 248 >1EQ9-A nrPDB Length = 222 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 74/232 (31%), Positives = 112/232 (48%), Gaps = 20/232 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86 IVGG +A PY SL++ GSH CG +++ + VLTAAHC+ + + V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 + + + + V +N NYD NDV L+ L++P + V ++L D+ Sbjct: 58 TNYL---SESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDED 114 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--------VTFFCRPHNICTFVPRRKAG 197 + C GWG LQE+ + V + +ICT + +R G Sbjct: 115 LES-NPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICT-LTKRGEG 172 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 C GDSGGPL+ +G GI SF CA PD +TRV+ +V WI + L++ Sbjct: 173 ACHGDSGGPLVANGAQIGIVSFGS-PCALGE-PDVYTRVSSFVSWINANLKK 222 >1YM0-A nrPDB Length = 238 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 73/240 (30%), Positives = 111/240 (46%), Gaps = 25/240 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG EA+P+ P+ S++ R + SHFCGG++I+ +V+ AAHC++ LV++V+G Sbjct: 1 IVGGIEARPYEFPWQVSVR-RKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGE 59 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQ-QDQP 145 H+ +Q V +F+N NYD NDV +I+ + +V + P + Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDY 119 Query: 146 VPHGTQCLAMGWGRVGAHD---PPAQVLQELNVT--------VVTFFCRPHNICTFVPRR 194 V +QC GWG + + P LN+T + IC Sbjct: 120 VYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTG 177 Query: 195 --KAGICFGDSGGPLICDG-----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 C GDSGGPL + GI S+ I GCA +P ++RV + WI T+ Sbjct: 178 MTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCA-SGYPGVYSRVGFHAGWITDTI 235 >5LPF-A nrPDB Length = 234 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 97/236 (41%), Gaps = 28/236 (11%) Query: 31 GHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNV 90 G S+P+ SL N S C G L+ S+VLTAAHC V G ++ Sbjct: 7 GSPCARGSQPWQVSL---FNGLSFHCAGVLVDQSWVLTAAHC--GNKPLWARV--GDDHL 59 Query: 91 RTQEPTQQHFSVAQVFLNNYDA--------ENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 + Q + V Y +D++L++L+ P L V +QLP + Sbjct: 60 LLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYR 119 Query: 143 DQPVPHGTQCLAMGWGRVGAHDPPAQV-LQELNVTVVT---------FFCRPHNICTFVP 192 G QC GWG A L ++T+++ + IC Sbjct: 120 CA--QPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-L 176 Query: 193 RRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 R C DSGGPL+CD +QGI S+ ++ C + P +T++ Y+ WI +R Sbjct: 177 DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 232 >2OLG-A nrPDB Length = 278 Score = 206 bits (524), Expect = 8e-54, Method: Composition-based stats. Identities = 67/262 (25%), Positives = 111/262 (42%), Gaps = 40/262 (15%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPG--SHFCGGTLIHPSFVLTAAHCLRDIPQRLV 81 A +I+ G + P P+ A + + + CGG+LI+ +++TAAHC+ R+V Sbjct: 19 EADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVV 78 Query: 82 ----NVVLGAHNVRTQEPTQQHFSV------------AQVFLNNY--DAENKLNDVLLIQ 123 V LG N T V + +Y ++++ +D+ LI+ Sbjct: 79 GALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIR 138 Query: 124 LSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFF-- 181 L+ + + V LPQ ++ V G + +GWGR + + Q+L V VV Sbjct: 139 LNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAVPVVHAEQC 197 Query: 182 ----------CRPHNICTFVPRRKAGICFGDSGGPLICDG-----IIQGIDSFVIWGCAT 226 R +C + C GDSGGPL+ + ++G+ SF C T Sbjct: 198 AKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGAT-CGT 255 Query: 227 RLFPDFFTRVALYVDWIRSTLR 248 +P +T+V Y DWI +R Sbjct: 256 EGWPGIYTKVGKYRDWIEGNIR 277 >2XRC-A nrPDB Length = 565 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 91/241 (37%), Gaps = 28/241 (11%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 R IVGG AQ P+ +++ + CGG I ++LTAAHCLR + Sbjct: 318 RRKRIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQI 374 Query: 84 VLGAHNVRTQEPTQQHFSVAQ----VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQL 139 V P + + +F NY+A ND+ LI++ N + Sbjct: 375 W--TTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI 432 Query: 140 PQQDQPVP----HGTQCLAMGWGRVGAHDPPAQVLQELNVTVV--------TFFCRPHNI 187 P P C+ GWGR ++ LQ V ++ F Sbjct: 433 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEME 491 Query: 188 CTFVPRRKAGICFGDSGGPLICDG-----IIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242 C C GDSGGPL+C + G+ S+ C FP +T+VA Y DW Sbjct: 492 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDW 550 Query: 243 I 243 I Sbjct: 551 I 551 >2QY0-B nrPDB Length = 242 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 60/252 (23%), Positives = 94/252 (37%), Gaps = 38/252 (15%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR-----LVN 82 I+GG +A+ + P+ + G GG L+ ++LTAAH L ++ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 83 VVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN---DVLLIQLSSPANLSASVATVQL 139 V LG NV H +Y + N D+ L++L + L ++ + L Sbjct: 56 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 115 Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------------FFCRPH 185 P D G G+G + A L+ + + V + Sbjct: 116 PDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 173 Query: 186 NICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALY 239 C P K C GDSGG P + GI S+ I GC+ F+T+V Y Sbjct: 174 MFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKVLNY 230 Query: 240 VDWIRSTLRRVE 251 VDWI+ + + Sbjct: 231 VDWIKKEMEEED 242 >4IGD-A nrPDB Length = 406 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 65/253 (25%), Positives = 99/253 (39%), Gaps = 37/253 (14%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD---------- 75 A+I G AQ + P++A L G FCGG+L+ S+++TAAHCL Sbjct: 154 AQIFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLR 211 Query: 76 ----IPQRLVNVVLGAHNVRTQEPTQQHFSVAQV-FLNNYDAENKLNDVLLIQLSSPANL 130 + ++LG H + +QH V YD NDV L++L L Sbjct: 212 DSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVL 271 Query: 131 SASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------- 180 +A V + LP + P G + GWG+ P + L E+ + +V Sbjct: 272 NAFVMPICLP--EGPQQEGAMVIVSGWGKQFLQRFP-ETLMEIEIPIVDHSTCQKAYAPL 328 Query: 181 --FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQG---IDSFVIWG--CATRLFPDFF 233 IC C GDSGGP++ +G + V WG C + + Sbjct: 329 KKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVY 388 Query: 234 TRVALYVDWIRST 246 + + DWI+ Sbjct: 389 SYIHHNKDWIQRV 401 >1GPZ-A nrPDB Length = 399 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 95/255 (37%), Gaps = 38/255 (14%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR----- 79 +I+GG +A+ + P+ + G GG L+ ++LTAAH L Sbjct: 155 RQQIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNA 209 Query: 80 LVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN---DVLLIQLSSPANLSASVAT 136 ++V LG NV H +Y + N D+ L++L + L ++ Sbjct: 210 SLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLP 269 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------------FFC 182 + LP D G G+G + A L+ + + V Sbjct: 270 ICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVF 327 Query: 183 RPHNICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRV 236 + C P K C GDSGG P + GI S+ I GC+ F+T+V Sbjct: 328 SQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKV 384 Query: 237 ALYVDWIRSTLRRVE 251 YVDWI+ + + Sbjct: 385 LNYVDWIKKEMEEED 399 >5KWM-A nrPDB Length = 230 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 66/224 (29%), Positives = 93/224 (41%), Gaps = 18/224 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG +A P+ +L G FCGGTL P+ V+TAAHC +NVV G Sbjct: 1 IVGGEDANVQDHPFTVALVT--PDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGR 58 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP-V 146 + + E T + V Y K DV ++ L +P A ++L + D Sbjct: 59 TVMSSNEGTVSKVTNVWV-HPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGY 113 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRRKAG 197 T +GWG A LQ+ V V + + +C VP Sbjct: 114 APDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVD 173 Query: 198 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241 C GDSGGP++ + + G+ S+ GCA P + RV Y D Sbjct: 174 TCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYD 216 >4DJZ-B nrPDB Length = 251 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 64/251 (25%), Positives = 97/251 (38%), Gaps = 37/251 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD------------ 75 I G AQ + P++A L G FCGG+L+ S+++TAAHCL Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 76 --IPQRLVNVVLGAHNVRTQEPTQQHFSVAQV-FLNNYDAENKLNDVLLIQLSSPANLSA 132 + ++LG H + +QH V YD NDV L++L L+A Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 133 SVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF------------ 180 V + LP + P G + GWG+ P + L E+ + +V Sbjct: 119 FVMPICLP--EGPQQEGAMVIVSGWGKQFLQRFP-ETLMEIEIPIVDHSTCQKAYAPLKK 175 Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQG---IDSFVIWG--CATRLFPDFFTR 235 IC C GDSGGP++ +G + V WG C + ++ Sbjct: 176 KVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSY 235 Query: 236 VALYVDWIRST 246 + DWI+ Sbjct: 236 IHHNKDWIQRV 246 >2B9L-A nrPDB Length = 394 Score = 200 bits (508), Expect = 7e-52, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 115/258 (44%), Gaps = 41/258 (15%) Query: 32 HEAQPHSRPYMAS-LQMRGNPGS----HFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVV 84 +EA+ P+M + L+ PGS CGG+LI PS VLT AHC+ L + + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 85 LGAHNVRTQEPTQ--QHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQ 141 G + T++ Q + QV ++ N++ + +NDV L+ L P + ++ T+ LPQ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 142 QDQPVPHGTQCLAMGWGR--VGAHDPPAQVLQELNVTVVT----------------FFCR 183 Q Q T+C A GWG+ G+ + +L+++ + V F Sbjct: 255 QSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 184 PHNICTFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFPDFFTRV 236 +C + C GD G PL C + GI ++ I GC P + V Sbjct: 314 QTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI-GCGDENVPGVYANV 371 Query: 237 ALYVDWIRSTLRRVEAKG 254 A + +WI + ++AKG Sbjct: 372 AHFRNWID---QEMQAKG 386 >1MD7-A nrPDB Length = 328 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 59/252 (23%), Positives = 93/252 (36%), Gaps = 38/252 (15%) Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQR----- 79 I+GG +A+ + P+ + G GG L+ ++LTAAH L Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNA 141 Query: 80 LVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN---DVLLIQLSSPANLSASVAT 136 ++V LG NV H +Y + N D+ L++L + L ++ Sbjct: 142 SLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLP 201 Query: 137 VQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------------FFC 182 + LP D G G+G + A L+ + + V Sbjct: 202 ICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVF 259 Query: 183 RPHNICTFVPRRKAGICFGDSGG------PLICDGIIQGIDSFVIWGCATRLFPDFFTRV 236 + C P K C GD+GG P + GI S+ I GC+ F+T+V Sbjct: 260 SQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKV 316 Query: 237 ALYVDWIRSTLR 248 YVDWI+ + Sbjct: 317 LNYVDWIKKEME 328 >5O32-I nrPDB Length = 244 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 90/237 (37%), Gaps = 28/237 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG AQ P+ +++ + CGG I ++LTAAHCLR + Sbjct: 1 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIW--T 55 Query: 88 HNVRTQEPTQQHFSVAQ----VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 V P + + +F NY+A ND+ LI++ N +P Sbjct: 56 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 115 Query: 144 QPVP----HGTQCLAMGWGRVGAHDPPAQVLQELNVTVV--------TFFCRPHNICTFV 191 P C+ GWGR ++ LQ V ++ F C Sbjct: 116 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGT 174 Query: 192 PRRKAGICFGDSGGPLICDG-----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWI 243 C GDSGGPL+C + G+ S+ C FP +T+VA Y DWI Sbjct: 175 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWI 230 >5UBM-A nrPDB Length = 252 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 100/259 (38%), Gaps = 50/259 (19%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG +A + P+ NP + GG LI+ +VLTAAH + R + +G Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWA---GGALINEYWVLTAAHVVEGN--REPTMYVG 52 Query: 87 AHNVRTQE-PTQQHFSVAQVFLNNY--------DAENKLNDVLLIQLSSPANLSASVATV 137 + +V+T + + VF++ N ND+ L++L P + +V+ + Sbjct: 53 STSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 112 Query: 138 QLP--QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------------- 178 LP D + G L GWGR D A L+ + V Sbjct: 113 CLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 179 -TFFCRPHNICTFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFP 230 + P+ IC + C GDSGG G+ S+ C T Sbjct: 172 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 231 DFFTRVALYVDWIRSTLRR 249 +TRV YVDWI T++ Sbjct: 227 GLYTRVKNYVDWIMKTMQE 245 >6BQM-A nrPDB Length = 506 Score = 193 bits (492), Expect = 4e-50, Method: Composition-based stats. Identities = 59/248 (23%), Positives = 103/248 (41%), Gaps = 32/248 (12%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 ++ I+GG +A PYM +L R + FCGG+ + +VLTAAHC+ +V Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTARNSS-HVFCGGSYLGGRYVLTAAHCVDKEDPAKGDV 65 Query: 84 VLGAHNVRTQEPTQQHFSVAQVFLNN-YDAENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 +LGA ++ T + V Q++++N Y + ND+ +++L SV + Sbjct: 66 LLGAFDMNDVN-TAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSSD 123 Query: 143 DQPVPHGTQCLAMGWGR----VGAHDPPAQVLQELNVTVVTF-FCRP------------- 184 + + +G+G G PA +L ++ V V C+ Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 185 ---HNICTFVPRRKAGICFGDSGGPLICDGI----IQGIDSFVIWGCATRLFPDFFTRVA 237 + C C GD+GGP+ D G+ S+ GC P +T ++ Sbjct: 184 LTNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGD-GCGRANSPGVYTNLS 240 Query: 238 LYVDWIRS 245 ++ DW+ Sbjct: 241 VFNDWLDD 248 >1ELV-A nrPDB Length = 333 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 100/259 (38%), Gaps = 50/259 (19%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG +A + P+ NP + GG LI+ +VLTAAH + R + +G Sbjct: 82 RIIGGSDADIKNFPWQVFF---DNPWA---GGALINEYWVLTAAHVVEGN--REPTMYVG 133 Query: 87 AHNVRTQE-PTQQHFSVAQVFLNNY--------DAENKLNDVLLIQLSSPANLSASVATV 137 + +V+T + + VF++ N ND+ L++L P + +V+ + Sbjct: 134 STSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 193 Query: 138 QLP--QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------------- 178 LP D + G L GWGR D A L+ + V Sbjct: 194 CLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADA 252 Query: 179 -TFFCRPHNICTFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATRLFP 230 + P+ IC + C GDSGG G+ S+ C T Sbjct: 253 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 307 Query: 231 DFFTRVALYVDWIRSTLRR 249 +TRV YVDWI T++ Sbjct: 308 GLYTRVKNYVDWIMKTMQE 326 >1SI5-H nrPDB Length = 240 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 106/238 (44%), Gaps = 30/238 (12%) Query: 28 IVGG--HEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 +V G +M SL+ R H CGG+LI S+VLTA C + L Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRN---KHICGGSLIKESWVLTARQCFPSRDLKDYEAWL 54 Query: 86 GAHNV--RTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G H+V R E +Q +V+Q+ Y E D++L++L+ PA L V+T+ LP Sbjct: 55 GIHDVHGRGDEKCKQVLNVSQLV---YGPEGS--DLVLMKLARPAVLDDFVSTIDLPNYG 109 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHN----------ICTFVP 192 +P T C GWG G + +L+ ++ ++ C H+ IC Sbjct: 110 STIPEKTSCSVYGWGYTGLIN-YDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAE 168 Query: 193 RRKAGICFGDSGGPLICDGIIQGIDSFVI---WGCATRLFPDFFTRVALYVDWIRSTL 247 + +G C GD GGPL+C+ + VI GCA P F RVA Y WI + Sbjct: 169 KIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >2ASU-B nrPDB Length = 234 Score = 191 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 108/238 (45%), Gaps = 29/238 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRD--IPQRLVNVVL 85 +VGGH P + P+ SL R G HFCGG+L+ ++LTA C +P V L Sbjct: 1 VVGGH---PGNSPWTVSL--RNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 86 GA--HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQD 143 G N + EP+ Q VA++ ++ ++L++L L+ VA + LP + Sbjct: 56 GTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ-----LVLLKLERSVTLNQRVALICLPPEW 110 Query: 144 QPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPRR 194 VP GT+C GWG VL + V++ R +CT Sbjct: 111 YVVPPGTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLA 169 Query: 195 KAGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 G C GD GGPL C +++GI CA +P FTRV+++VDWI +R Sbjct: 170 PVGACEGDYGGPLACFTHNSWVLEGII-IPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >3H7O-A nrPDB Length = 228 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 59/229 (25%), Positives = 102/229 (44%), Gaps = 12/229 (5%) Query: 30 GGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHN 89 GG + P+ +++ S CGG ++ FVLTAAHC+ D + + + N Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 90 VRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSA-SVATVQLPQQDQPVPH 148 + ++P + V+ V+L+ Y E ND+ +++LS P L +LP + Sbjct: 62 LW-EDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 149 GTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRPHNICTF-----VPRRKAGIC--F 200 G+ L G+G DP L+ +TVV CR F +K G+ Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLES 180 Query: 201 GDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GD+G P + + G+ ++ + P+ FT+V YV WI+ +++ Sbjct: 181 GDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >3I77-A nrPDB Length = 230 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 67/241 (27%), Positives = 88/241 (36%), Gaps = 29/241 (12%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L N G FCGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG--FCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V + E D LI+L+ P N + +AT Q Sbjct: 59 V-VDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 117 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH---------NICTFVP-RR 194 GWG + L + NV V CR IC P Sbjct: 118 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 195 KAGICFGDSGGPLI-----CDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 C GDSGGP+ + I GI S+ +GCA +P +T V+ + I S R Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASAIASAART 229 Query: 250 V 250 + Sbjct: 230 L 230 >1M9U-A nrPDB Length = 241 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 65/240 (27%), Positives = 105/240 (43%), Gaps = 21/240 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 ++GG A P P+ S Q + SH CG +L+ + L+A+HC+ + + V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAEN--KLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 TQ + NY A ND+ ++ L++ +L ++ LP + Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR------------PHNICTFVP 192 GT C+ GWGR + +LQ+ ++ V+ T C ++IC P Sbjct: 121 DYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQDP 180 Query: 193 RRKAGICFGDSGGPLICDG---IIQGIDSFVI---WGCATRLFPDFFTRVALYVDWIRST 246 G C GDSGGPL C + G+ S+V+ G +P +TRV+ Y+ WI Sbjct: 181 AGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWIGDN 240 >4J1Y-A nrPDB Length = 397 Score = 187 bits (476), Expect = 3e-48, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 100/262 (38%), Gaps = 50/262 (19%) Query: 24 RAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNV 83 A +GG +A + P+ NP + GG LI+ +VLTAAH + R + Sbjct: 143 EKARAIGGSDADIKNFPWQVFF---DNPWA---GGALINEYWVLTAAHVVEGN--REPTM 194 Query: 84 VLGAHNVRTQE-PTQQHFSVAQVFLNNY--------DAENKLNDVLLIQLSSPANLSASV 134 +G+ +V+T + + VF++ N ND+ L++L P + +V Sbjct: 195 YVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTV 254 Query: 135 ATVQLP--QQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-------------- 178 + + LP D + G L GWGR D A L+ + V Sbjct: 255 SPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPT 313 Query: 179 ----TFFCRPHNICTFVPRRKAGICFGDSGGPLICDG-------IIQGIDSFVIWGCATR 227 + P+ IC + C GDSGG G+ S+ C T Sbjct: 314 ADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT- 370 Query: 228 LFPDFFTRVALYVDWIRSTLRR 249 +TRV YVDWI T++ Sbjct: 371 --YGLYTRVKNYVDWIMKTMQE 390 >3BEU-A nrPDB Length = 224 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 85/240 (35%), Gaps = 33/240 (13%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L M CGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V + E D LI+L+ P N + +AT Q Sbjct: 54 V-VDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 112 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH---------NICTFVPRRK 195 GWG + L + NV V CR IC ++ Sbjct: 113 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQ 165 Query: 196 AGICFGDSGGPLI-----CDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 C GDSGGP+ + + GI S+ GCA + +T V+ + I S R + Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSWG-EGCARKGKYGVYTEVSTFASAIASAARTL 224 >2HLC-A nrPDB Length = 230 Score = 180 bits (458), Expect = 4e-46, Method: Composition-based stats. Identities = 61/234 (26%), Positives = 97/234 (41%), Gaps = 24/234 (10%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSH-FCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+ G+EA PY A L + +CGG+LI ++LTAAHC+ V+VV+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCV----HDAVSVVVY 56 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + E S + + ++ + LNDV LI++ + ++ ++LP ++ Sbjct: 57 LGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELN 115 Query: 147 PHGTQCL--AMGWGRVGAHDPPAQVLQ-ELNVTVVTFFCRP---------HNICTFVPRR 194 GWG + +LQ N+ + C IC Sbjct: 116 NKFENIWATVSGWG---QSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSD 171 Query: 195 KAGICFGDSGGPLIC--DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246 CFGDSGGP + ++ G+ SFV P F+RV Y+DWI+ Sbjct: 172 GKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQN 225 >1PQ7-A nrPDB Length = 224 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 55/229 (24%), Positives = 88/229 (38%), Gaps = 20/229 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IVGG A P++ S+ G P CGG+L++ + VLTAAHC+ Q + G Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPW---CGGSLLNANTVLTAAHCVSGYAQSGFQIRAG- 56 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVP 147 ++ + +Y N ND+ +++LS+ ++ +L Sbjct: 57 -SLSRTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPV 113 Query: 148 HGTQCLAMGWGRVGAHDPPAQV-LQELNVTVVTF-FCRP---------HNICTFVPRRKA 196 G+ GWG V L ++ V +V+ CR C V Sbjct: 114 AGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGK 173 Query: 197 GICFGDSGGPLI-CDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIR 244 C GDSGGP++ + G S+ GCA + + V +I Sbjct: 174 DSCQGDSGGPIVDSSNTLIGAVSWGN-GCARPNYSGVYASVGALRSFID 221 >3H7T-A nrPDB Length = 235 Score = 177 bits (450), Expect = 3e-45, Method: Composition-based stats. Identities = 54/245 (22%), Positives = 95/245 (38%), Gaps = 27/245 (11%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG ++ P+ + + P FCGG+++ +FV+TAA C+ +++ G+ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKP---FCGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 88 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSA-SVATVQLPQQDQPV 146 T+ ++++ Y N+ +I+ P L + ++LP Sbjct: 58 SYRTTK---GTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDP 114 Query: 147 PHGTQCLAMGWGRVGAHD-PPAQVLQELNVTVV--------------TFFCRPHNICTFV 191 T L GWG + L E N TVV + C Sbjct: 115 EPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGG 174 Query: 192 PRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVE 251 + I +GD+G P + +G + G+ S++ FP F RV YV I+ + Sbjct: 175 EYDETYIGYGDAGDPAVQNGTLVGVASYISS--MPSEFPSVFLRVGYYVLDIKDII---S 229 Query: 252 AKGRP 256 K +P Sbjct: 230 GKVKP 234 >5XW8-A nrPDB Length = 133 Score = 174 bits (441), Expect = 3e-44, Method: Composition-based stats. Identities = 56/137 (40%), Positives = 80/137 (58%), Gaps = 11/137 (8%) Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85 +IVGG+ +S PY SL N GSHFCGG+LI+ +V++AAHC + + V L Sbjct: 7 DKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRL 58 Query: 86 GAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144 G HN+ E +Q + A++ N++ ND++LI+LSSPA L++ VATV LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 145 PVPHGTQCLAMGWGRVG 161 GT+CL GWG Sbjct: 119 --AAGTECLISGWGNTK 133 >2FMJ-A nrPDB Length = 222 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 83/240 (34%), Gaps = 35/240 (14%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 +VGG A P+M L M CGG L VLTAAHC+ G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 88 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDVLLIQLSSPANL-SASVATVQLPQQDQP 145 V Q + +V Y+ D LI+L+ P N + +AT Q Sbjct: 54 V-VDLQSSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPINQPTLKIATTTAYNQGTF 110 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRP---------HNICTFVPRRK 195 GWG + L + NV V CR IC Sbjct: 111 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 196 AGICFGDSGGPLI-----CDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 C GDSGGP+ + I GI S+ GCA + +T V+ + I S R + Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWG-EGCARKGKYGVYTEVSTFASAIASAARTL 222 >2PKA-B nrPDB Length = 152 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 45/151 (29%), Positives = 76/151 (50%), Gaps = 14/151 (9%) Query: 111 DAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPP---A 167 D ++ +D++L++L SPA ++ +V ++LP Q+ + G+ C A GWG + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 168 QVLQELNVTVV-TFFC--------RPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDS 218 +Q + +T++ FC +C C GDSGGPLIC+G+ QGI S Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITS 119 Query: 219 FVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 + C + P +T++ Y+DWI T+ Sbjct: 120 WGHTPCGSANKPSIYTKLIFYLDWIDDTITE 150 >3VGC-B nrPDB Length = 131 Score = 163 bits (412), Expect = 9e-41, Method: Composition-based stats. Identities = 52/135 (38%), Positives = 73/135 (54%), Gaps = 6/135 (4%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 IV G EA P S P+ SLQ G HFCGG+LI+ ++V+TAAHC + V VV G Sbjct: 1 IVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVVTAAHC--GVTTSDV-VVAGE 55 Query: 88 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 + + Q +A+VF N Y++ ND+ L++LS+ A+ S +V+ V LP Sbjct: 56 FDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 115 Query: 147 PHGTQCLAMGWGRVG 161 GT C+ GWG Sbjct: 116 AAGTTCVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 159 bits (404), Expect = 7e-40, Method: Composition-based stats. Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 6/132 (4%) Query: 31 GHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNV 90 G +A P S P+ SLQ G HFCGG+LI +V+TAAHC + VV G + Sbjct: 1 GEDAIPGSWPWQVSLQ--DKTGFHFCGGSLISEDWVVTAAHC---GVKTSDVVVAGEFDQ 55 Query: 91 RTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHG 149 + E Q +AQVF N ++ ND+ L++L++PA S +V+ V LP D P G Sbjct: 56 GSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPG 115 Query: 150 TQCLAMGWGRVG 161 T C GWG+ Sbjct: 116 TVCATTGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 13/148 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 82 NVVLGAHNVRTQEPT-QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQ 138 V +G H+ E ++ + +++++ Y+ L+ D+ L++L P S + V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGRVGAH 163 LP ++ + G + GWG + Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 13/148 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + Sbjct: 1 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 82 NVVLGAHNVRTQE-PTQQHFSVAQVFLN-NYDA-ENKLNDVLLIQLSSPANLSASVATVQ 138 V +G H+ E ++ + +++++ Y+ EN D+ L++L P LS + V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 139 LPQQDQP---VPHGTQCLAMGWGRVGAH 163 LP + + G + GWG Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >4F4O-C nrPDB Length = 347 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 56/253 (22%), Positives = 91/253 (35%), Gaps = 42/253 (16%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GG S P+ A + N S G TLI+ ++LT A LR + Sbjct: 102 RIMGGSLDAKGSFPWQAKMISHHNLTS---GATLINEQWLLTTAKNLRLGHKNDTKAKDI 158 Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146 A +R +Q + +V + ++ D+ LI+L ++ V + LP +D V Sbjct: 159 APTLRLYVGKKQEVEIEKVIFHPDNSTV---DIGLIKLKQKVPVNERVMPICLPSKDY-V 214 Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--------------------------VTF 180 G GWGR + + L+ + + V V Sbjct: 215 NVGLVGYVSGWGRNANLNFT-EHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQP 273 Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPDFFT 234 H C + + + C+GD+G GI SF C T + Sbjct: 274 ILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSF-DKSCRTAE-YGVYV 331 Query: 235 RVALYVDWIRSTL 247 RV +DWI++T+ Sbjct: 332 RVTSILDWIQTTI 344 >4X0L-C nrPDB Length = 259 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 88/256 (34%), Gaps = 44/256 (17%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GGH S P+ A + N + G TLI+ ++LT A L Sbjct: 14 RILGGHLDAKGSFPWQAKMVSHHNLTT---GATLINEQWLLTTAKNLFLNHSENATAKDI 70 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 A + +Q + +V L+ NY D+ LI+L +++ V + LP +D Sbjct: 71 APTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY- 125 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--------------------------VT 179 G GWGR A+ L+ + + V V Sbjct: 126 AEVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQ 184 Query: 180 FFCRPHNICTFVPRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPDFF 233 H C + + + C+GD+G GI SF CA + Sbjct: 185 PILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-DKSCAVAE-YGVY 242 Query: 234 TRVALYVDWIRSTLRR 249 +V DW++ T+ Sbjct: 243 VKVTSIQDWVQKTIAE 258 >2WIN-I nrPDB Length = 507 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 61/280 (21%), Positives = 94/280 (33%), Gaps = 69/280 (24%) Query: 34 AQPHSRPYMASL-QMRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVR 91 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG---- 284 Query: 92 TQEPTQQHFSVAQVFLNNYD---------AENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 E V +F NY+ E DV LI+L + ++ + LP Sbjct: 285 --EKRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT 341 Query: 143 DQP-----VPHGTQCLAMGWGRVGAHDPPAQVLQE------------------------- 172 + +P T C + A D A + E Sbjct: 342 EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 401 Query: 173 ------LNVTVVTFFCRPHNICTFV--PRRKAGICFGDSGGPLICDGIIQGI-DSFVIWG 223 V ++ P +CT P C GDSGGPLI + I + WG Sbjct: 402 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 Query: 224 ----CA----TRLFP----DFFTRVALYVDWIRSTLRRVE 251 C + P DF + + W++ L+ + Sbjct: 462 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 501 >4WJG-C nrPDB Length = 315 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 88/256 (34%), Gaps = 44/256 (17%) Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86 I+GGH S P+ A + N + G TLI+ ++LT A L Sbjct: 70 RILGGHLDAKGSFPWQAKMVSHHNLTT---GATLINEQWLLTTAKNLFLNHSENATAKDI 126 Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145 A + +Q + +V L+ NY D+ LI+L +++ V + LP +D Sbjct: 127 APTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY- 181 Query: 146 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--------------------------VT 179 G GWGR A+ L+ + + V V Sbjct: 182 AEVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQ 240 Query: 180 FFCRPHNICTFVPRRKAGICFGDSGGPLICD------GIIQGIDSFVIWGCATRLFPDFF 233 H C + + + C+GD+G GI SF CA + Sbjct: 241 PILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-DKSCAVAE-YGVY 298 Query: 234 TRVALYVDWIRSTLRR 249 +V DW++ T+ Sbjct: 299 VKVTSIQDWVQKTIAE 314 >1DLE-A nrPDB Length = 298 Score = 136 bits (344), Expect = 7e-33, Method: Composition-based stats. Identities = 61/280 (21%), Positives = 94/280 (33%), Gaps = 69/280 (24%) Query: 34 AQPHSRPYMASL-QMRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVR 91 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG---- 77 Query: 92 TQEPTQQHFSVAQVFLNNYD---------AENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 E V +F NY+ E DV LI+L + ++ + LP Sbjct: 78 --EKRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT 134 Query: 143 DQP-----VPHGTQCLAMGWGRVGAHDPPAQVLQE------------------------- 172 + +P T C + A D A + E Sbjct: 135 EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 194 Query: 173 ------LNVTVVTFFCRPHNICTFV--PRRKAGICFGDSGGPLICDGIIQGI-DSFVIWG 223 V ++ P +CT P C GDSGGPLI + I + WG Sbjct: 195 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 Query: 224 ----CA----TRLFP----DFFTRVALYVDWIRSTLRRVE 251 C + P DF + + W++ L+ + Sbjct: 255 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 294 >2OK5-A nrPDB Length = 752 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 61/280 (21%), Positives = 94/280 (33%), Gaps = 69/280 (24%) Query: 34 AQPHSRPYMASL-QMRGNPGSHFCGGTLIHPSFVLTAAHCLR-DIPQRLVNVVLGAHNVR 91 H +P+ A + +R + G C G ++ FVLTAAHC D + + V +G Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGG---- 528 Query: 92 TQEPTQQHFSVAQVFLNNYD---------AENKLNDVLLIQLSSPANLSASVATVQLPQQ 142 E V +F NY+ E DV LI+L + ++ + LP Sbjct: 529 --EKRDLEIEVV-LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT 585 Query: 143 DQP-----VPHGTQCLAMGWGRVGAHDPPAQVLQE------------------------- 172 + +P T C + A D A + E Sbjct: 586 EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 645 Query: 173 ------LNVTVVTFFCRPHNICTFV--PRRKAGICFGDSGGPLICDGIIQGI-DSFVIWG 223 V ++ P +CT P C GDSGGPLI + I + WG Sbjct: 646 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 Query: 224 ----CA----TRLFP----DFFTRVALYVDWIRSTLRRVE 251 C + P DF + + W++ L+ + Sbjct: 706 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 745 >1AKS-B nrPDB Length = 98 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%) Query: 161 GAHDPPAQVLQELNVTVVTFF---------CRPHNICTFVPRRKAGICFGDSGGPLICDG 211 + +LQ L V++ + IC + C GDSGGP++C+G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 212 IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 +QGI S+ +GCA + P +T+V YV+WI+ T+ Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTI 95 >3F1S-B nrPDB Length = 283 Score = 108 bits (271), Expect = 2e-24, Method: Composition-based stats. Identities = 53/224 (23%), Positives = 83/224 (37%), Gaps = 29/224 (12%) Query: 40 PYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQH 99 P+ L + G FCGG +I +FVLT A C + R + V N +Q+P Sbjct: 65 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITVKT-YFNRTSQDPLMIK 119 Query: 100 FSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP---VPHGTQCLAMG 156 + V + YDA+ ND+ L++L P + V P++D + T+ L G Sbjct: 120 ITHVHVHM-RYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 178 Query: 157 WGRVGAH-----DPPAQVL-------QELNVTVVTF-FCRPHNICTFVPRRKAGICFGDS 203 W R G L Q LNVTV T +C ++ + + Sbjct: 179 WARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHR 238 Query: 204 GGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 G + G+ G T+V+ Y W + + Sbjct: 239 G-----SWFLTGVLGSQPVG-GQAHMVLV-TKVSRYSLWFKQIM 275 >2I6S-A nrPDB Length = 517 Score = 106 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 48/250 (19%), Positives = 84/250 (33%), Gaps = 63/250 (25%) Query: 29 VGGHEAQPHSR---PYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-RDIPQRLVNVV 84 VG A + P+ +++ + C G LI +VLTAAHC L V Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQE---TCRGALISDQWVLTAAHCFRDGNDHSLWRVN 286 Query: 85 LGAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLN---------DVLLIQLSSPANLSASV 134 +G + + F + + V +D K N D+ L++L+ +S Sbjct: 287 VG----DPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHA 342 Query: 135 ATVQLPQQDQPV-----PHGTQC----------------------------LAMG--WGR 159 + LP + P G+ C L MG W Sbjct: 343 RPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTS 402 Query: 160 VGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQ----G 215 + + N+T V +C+ ++ C G+SGG + + + G Sbjct: 403 CAEVVSQEKTMFP-NLTDVREVVTDQFLCSGTQEDES-PCKGESGGAVFLERRFRFFQVG 460 Query: 216 IDSFVIW-GC 224 + S+ ++ C Sbjct: 461 LVSWGLYNPC 470 >3H5C-B nrPDB Length = 317 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 53/224 (23%), Positives = 83/224 (37%), Gaps = 29/224 (12%) Query: 40 PYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQH 99 P+ L + G FCGG +I +FVLT A C + R + V N +Q+P Sbjct: 106 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITVKT-YFNRTSQDPLMIK 160 Query: 100 FSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP---VPHGTQCLAMG 156 + V + YDA+ ND+ L++L P + V P++D + T+ L G Sbjct: 161 ITHVHVHM-RYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 219 Query: 157 WGRVGAH-----DPPAQVL-------QELNVTVVTF-FCRPHNICTFVPRRKAGICFGDS 203 W R G L Q LNVTV T +C ++ + + Sbjct: 220 WARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHR 279 Query: 204 GGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 G + G+ G T+V+ Y W + + Sbjct: 280 G-----SWFLTGVLGSQPVG-GQAHMVLV-TKVSRYSLWFKQIM 316 >2KAI-A nrPDB Length = 80 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 7/82 (8%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 87 I+GG E + +S P+ ++ + S CGG L++P +VLTAAHC V LG Sbjct: 1 IIGGRECEKNSHPWQVAIY---HYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVWLGR 53 Query: 88 HNVRTQEPTQQHFSVAQVFLNN 109 HN+ E T Q F V F + Sbjct: 54 HNLFENENTAQFFGVTADFPHP 75 >1EPT-B nrPDB Length = 82 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 79 RLVNVVLGAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANLSASVATV 137 + V LG HN+ E +Q + A++ N++ ND++LI+LSSPA L++ VATV Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 138 QLPQQDQPVPHGTQCLAMGWGRVG 161 LP+ GT+CL GWG Sbjct: 61 SLPRSCA--AAGTECLISGWGNTK 82 >1BBR-E nrPDB Length = 109 Score = 92.6 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 36/103 (34%), Gaps = 19/103 (18%) Query: 166 PAQVLQELNVTVVTF---------FCRPHNICTFV---PRRKAGICFGDSGGPLICD--- 210 VLQ +N+ +V + C ++ C GDSGGP + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 211 ---GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRV 250 GI S+ GC F+T V WI+ + R+ Sbjct: 66 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVIDRL 107 >2HNT-F nrPDB Length = 105 Score = 91.8 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 35/102 (34%), Gaps = 19/102 (18%) Query: 166 PAQVLQELNVTVVTF---------FCRPHNICTFV---PRRKAGICFGDSGGPLICD--- 210 VLQ +N+ +V + C ++ C GDSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 211 ---GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249 GI S+ GC F+T V WI+ + + Sbjct: 62 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >2HNT-C nrPDB Length = 70 Score = 85.6 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 7/71 (9%) Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL------RDIPQRLV 81 IV G +A+ P+ L R +P CG +LI +VLTAAHCL ++ + + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 82 NVVLGAHNVRT 92 V +G H+ Sbjct: 60 LVRIGKHSRTR 70 >3RU4-E nrPDB Length = 96 Score = 81.4 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 16/95 (16%) Query: 166 PAQVLQELNVTVVTFF---------CRPHNICTFVPRRKAGICFGDSGGPLICD----GI 212 LQ+ ++ +++ + IC C GDSGGPL+C Sbjct: 2 TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAWT 59 Query: 213 IQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247 + GI S+ C+T P + RV V+W++ TL Sbjct: 60 LVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 79.9 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 16/96 (16%) Query: 166 PAQVLQELNVTVVTF---------FCRPHNICTFVPRRKAGICFGDSGGPLICD----GI 212 + LQ+ + +V+ C C GDSGGPL+C Sbjct: 5 TPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGVWT 62 Query: 213 IQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248 + GI S+ C+T P ++RV + W++ L Sbjct: 63 LAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILE 97 >2HNT-E nrPDB Length = 81 Score = 77.6 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 97 QQHFSVAQVFLN-NYDAENKLN-DVLLIQLSSPANLSASVATVQLPQQDQP---VPHGTQ 151 ++ + +++++ Y+ L+ D+ L++L P S + V LP ++ + G + Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 152 CLAMGWGRVGAH 163 GWG + Sbjct: 63 GRVTGWGNLKET 74 >1P3E-A nrPDB Length = 215 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 40/111 (36%), Gaps = 11/111 (9%) Query: 52 GSHFCGGTLIHPSFVLTAAHCLRDIPQRLV----NVVLGAHNVRTQEPTQQHFSVAQVFL 107 G C GTLI P+ +LT HC+ + R +V G ++ + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSA--NMTEFYVP 85 Query: 108 NNY-DAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGW 157 + Y + D +I+ + N+ +V + + GT G+ Sbjct: 86 SGYINTGASQYDFAVIKTDT--NIGNTVGYRSI--RQVTNLTGTTIKISGY 132 >1DUE-A nrPDB Length = 242 Score = 35.6 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 39/108 (36%), Gaps = 13/108 (12%) Query: 58 GTLIHPSFVLTAAHCLRDIPQRLVNVVLG-----AHNVRTQEPTQQHFSVAQVFLNNYDA 112 G LI + VLT H + V N T+ P + + V ++ + A Sbjct: 59 GVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGE-YEVKEILQEPFGA 117 Query: 113 ENKLNDVLLIQLSSP---ANLSASVATVQLPQQDQPVPHGTQCLAMGW 157 D+ LI+L +L ++ ++ + G + +G+ Sbjct: 118 GV---DLALIRLKPDQNGVSLGDKISPAKI-GTSNDLKDGDKLELIGY 161 >3LT3-A nrPDB Length = 217 Score = 35.2 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 65/162 (40%), Gaps = 27/162 (16%) Query: 58 GTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN 117 G +I P V+T AH VV G++NV + + + +YD Sbjct: 42 GFVISPDRVMTNAH-----------VVAGSNNVTVYAGDKPF----EATVVSYDPSV--- 83 Query: 118 DVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGW-GRVGAHDPPAQVLQELNVT 176 DV + L+ P + P + G + +G+ G PA++ + + ++ Sbjct: 84 DVAI--LAVPHLPPPPLVFAAEPAK-----TGADVVVLGYPGGGNFTATPARIREAIRLS 136 Query: 177 VVTFFCRPHNICTFVPRRKAGICFGDSGGPLI-CDGIIQGID 217 + P + V +A + GD+GGPLI +G + G+ Sbjct: 137 GPDIYGDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGVV 178 >2EA3-A nrPDB Length = 189 Score = 35.2 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 13/28 (46%) Query: 201 GDSGGPLICDGIIQGIDSFVIWGCATRL 228 GDSGG L+ QG+ S C T Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2OUA-A nrPDB Length = 188 Score = 33.6 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 26/94 (27%), Gaps = 20/94 (21%) Query: 141 QQDQPVPHGTQ----CLAMGW--GRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRR 194 P G+Q GW G + A + Q ++C Sbjct: 89 SGSSTAPIGSQVCRSGSTTGWYCGTIQARNQTVSYPQGTV-----HSLTRTSVCAEP--- 140 Query: 195 KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRL 228 GDSGG I QG+ S C T Sbjct: 141 ------GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >2SFA-A nrPDB Length = 191 Score = 33.6 bits (76), Expect = 0.078, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 20/73 (27%), Gaps = 2/73 (2%) Query: 158 GRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICF--GDSGGPLICDGIIQG 215 G+ L VT + + +C GDSGG L G Sbjct: 100 GQTVQRSGSTTGLHSGRVTGLNATVNYGGGDIVSGLIQTNVCAEPGDSGGALFAGSTALG 159 Query: 216 IDSFVIWGCATRL 228 + S C T Sbjct: 160 LTSGGSGNCRTGG 172 >2PFE-A nrPDB Length = 186 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 195 KAGICF--GDSGGPLICDGIIQGIDSFVIWGCATRL 228 + C GDSGGP + QG+ S C + Sbjct: 130 RTTACAEGGDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2SGA-A nrPDB Length = 181 Score = 32.1 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 23/73 (31%), Gaps = 2/73 (2%) Query: 158 GRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICF--GDSGGPLICDGIIQG 215 G+ L+ +VT + + + +C GDSGG L G Sbjct: 90 GQAVQRSGSTTGLRSGSVTGLNATVNYGSSGIVYGMIQTNVCAQPGDSGGSLFAGSTALG 149 Query: 216 IDSFVIWGCATRL 228 + S C T Sbjct: 150 LTSGGSGNCRTGG 162 >5XIG-A nrPDB Length = 500 Score = 30.6 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 19/39 (48%), Gaps = 8/39 (20%) Query: 129 NLSASVATVQLPQQDQPVPHGTQCLAMG--------WGR 159 ++ ++ T+ +P P+P GT+C G WGR Sbjct: 460 VMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGR 498 >5XIP-A nrPDB Length = 498 Score = 30.6 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 14/26 (53%) Query: 131 SASVATVQLPQQDQPVPHGTQCLAMG 156 + ++ + +P P+P GT+C G Sbjct: 460 TGAMKPLCIPFDQPPMPEGTRCFFTG 485 >4NCX-A nrPDB Length = 506 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 18/38 (47%) Query: 119 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMG 156 + L Q +S LS ++ + +P P+P +C G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >5ILB-A nrPDB Length = 474 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 30/91 (32%), Gaps = 21/91 (23%) Query: 32 HEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVR 91 H A +S P+ Q +I +LT AHC+ Q V+ Sbjct: 17 HTAPDYSLPWQKQRQFTSTGS-----AFMIGDGKLLTNAHCVEHDTQ-----------VK 60 Query: 92 TQEPTQQHFSVAQVFLNNYDAENKLNDVLLI 122 + VA+V + D D+ L+ Sbjct: 61 VKRRGDDRKYVAKVLVRGVDC-----DIALL 86 >4FLN-A nrPDB Length = 539 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 30/91 (32%), Gaps = 21/91 (23%) Query: 32 HEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVR 91 H A +S P+ Q +I +LT AHC+ Q V+ Sbjct: 57 HTAPDYSLPWQKQRQFTSTGS-----AFMIGDGKLLTNAHCVEHDTQ-----------VK 100 Query: 92 TQEPTQQHFSVAQVFLNNYDAENKLNDVLLI 122 + VA+V + D D+ L+ Sbjct: 101 VKRRGDDRKYVAKVLVRGVDC-----DIALL 126 >4FVB-A nrPDB Length = 152 Score = 29.0 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 201 GDSGGPLICDGIIQGIDSFVIWG 223 GD+GG L C + GI S G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >3W95-A nrPDB Length = 171 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 201 GDSGGPLICDGIIQGIDSFVIWG 223 GD+GG L C + GI S G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >3STJ-A nrPDB Length = 345 Score = 28.6 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 62/165 (37%), Gaps = 36/165 (21%) Query: 58 GTLIHPS--FVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENK 115 G +I+ S +VLT H + + + + G + F + + Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDG-----------REFDAKLI------GSDD 109 Query: 116 LNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNV 175 +D+ L+Q+ +P+ L+ + + D + G +A+G P + Q Sbjct: 110 QSDIALLQIQNPSKLTQ----IAIADSD-KLRVGDFAVAVG--------NPFGLGQTATS 156 Query: 176 TVVTFFCRPHNICTFVP---RRKAGICFGDSGGP-LICDGIIQGI 216 +V+ R + + A I G+SGG L +G + GI Sbjct: 157 GIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGI 201 >3STI-A nrPDB Length = 245 Score = 28.6 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 62/165 (37%), Gaps = 36/165 (21%) Query: 58 GTLIHPS--FVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENK 115 G +I+ S +VLT H + + + + G + F + + Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDG-----------REFDAKLI------GSDD 109 Query: 116 LNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNV 175 +D+ L+Q+ +P+ L+ + + D + G +A+G P + Q Sbjct: 110 QSDIALLQIQNPSKLTQ----IAIADSD-KLRVGDFAVAVG--------NPFGLGQTATS 156 Query: 176 TVVTFFCRPHNICTFVP---RRKAGICFGDSGGP-LICDGIIQGI 216 +V+ R + + A I G+SGG L +G + GI Sbjct: 157 GIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGI 201 >5X88-A nrPDB Length = 199 Score = 28.2 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 13/22 (59%), Positives = 13/22 (59%), Gaps = 5/22 (22%) Query: 50 NPGSHFCGGTLIHPSFVLTAAH 71 NPG C GTLI LTAAH Sbjct: 164 NPGDLVCDGTLI-----LTAAH 180 >1HPG-A nrPDB Length = 187 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 13/32 (40%), Gaps = 3/32 (9%) Query: 195 KAGICF--GDSGGPLICDGIIQGIDSFVIWGC 224 + C GDSGG + GI S GC Sbjct: 133 RTTACSAGGDSGGAHFAGSVALGIHS-GSSGC 163 >2BS9-A nrPDB Length = 503 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 1/27 (3%) Query: 204 GGPLICDGIIQGIDSFVIWGCATRLFP 230 GGP IC G + I F+ + CA R P Sbjct: 196 GGPAICGGSDEWITDFLHF-CAERRVP 221 >2HRV-A nrPDB Length = 142 Score = 27.9 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 13/27 (48%), Gaps = 1/27 (3%) Query: 195 KAGICF-GDSGGPLICDGIIQGIDSFV 220 G C GD GG L+C + GI + Sbjct: 97 GEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >2M5T-A nrPDB Length = 142 Score = 27.9 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 15/30 (50%), Gaps = 1/30 (3%) Query: 195 KAGICF-GDSGGPLICDGIIQGIDSFVIWG 223 G C GD+GG L+C + GI + G Sbjct: 96 GEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >4A8B-A nrPDB Length = 436 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 31/77 (40%), Gaps = 19/77 (24%) Query: 58 GTLIHPS--FVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENK 115 G +I+ S +VLT H + + + + G + F + + Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDG-----------REFDAKLI------GSDD 109 Query: 116 LNDVLLIQLSSPANLSA 132 +D+ L+Q+ +P+ L+ Sbjct: 110 QSDIALLQIQNPSKLTQ 126 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.159 0.569 Lambda K H 0.267 0.0484 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,289,112 Number of Sequences: 36641 Number of extensions: 480267 Number of successful extensions: 2956 Number of sequences better than 10.0: 187 Number of HSP's better than 10.0 without gapping: 326 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 1451 Number of HSP's gapped (non-prelim): 373 length of query: 256 length of database: 10,336,785 effective HSP length: 95 effective length of query: 161 effective length of database: 6,855,890 effective search space: 1103798290 effective search space used: 1103798290 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (20.7 bits) S2: 59 (27.1 bits)