BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23946 (247 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1NN6-A nrPDB 478 e-136 2RDL-A nrPDB 344 2e-95 3RP2-A nrPDB 284 2e-77 1EUF-A nrPDB 246 5e-66 1FI8-A nrPDB 242 1e-64 1KYN-A nrPDB 233 4e-62 1IAU-A nrPDB 228 2e-60 3TK9-A nrPDB 218 2e-57 3G01-A nrPDB 216 1e-56 1ORF-A nrPDB 160 4e-40 1FDP-A nrPDB 157 5e-39 1UTJ-A nrPDB 153 6e-38 1FUJ-A nrPDB 152 9e-38 1A0J-A nrPDB 151 2e-37 4NFE-A nrPDB 149 1e-36 5FXL-A nrPDB 146 8e-36 3BSQ-A nrPDB 145 1e-35 1F7Z-A nrPDB 145 1e-35 2TLD-E nrPDB 142 1e-34 4AN7-A nrPDB 142 1e-34 5C67-A nrPDB 140 3e-34 3QUM-P nrPDB 140 4e-34 5MS3-A nrPDB 138 3e-33 4WWY-A nrPDB 137 4e-33 1MZD-A nrPDB 136 1e-32 1GVZ-A nrPDB 135 1e-32 5FCR-A nrPDB 135 2e-32 1SPJ-A nrPDB 135 2e-32 4Q7Y-A nrPDB 134 3e-32 2EEK-A nrPDB 133 9e-32 5ZFH-A nrPDB 131 2e-31 1ELT-A nrPDB 131 3e-31 2BDH-A nrPDB 130 4e-31 1PYT-D nrPDB 127 3e-30 2V35-A nrPDB 127 4e-30 1BRU-P nrPDB 126 7e-30 2CGA-A nrPDB 125 2e-29 1TON-A nrPDB 124 3e-29 4H4F-A nrPDB 124 4e-29 2ZKS-A nrPDB 122 2e-28 1NPM-A nrPDB 120 5e-28 1SGF-G nrPDB 120 6e-28 1AO5-A nrPDB 119 1e-27 6QHB-A nrPDB 118 3e-27 1AZZ-A nrPDB 117 3e-27 1SGF-A nrPDB 116 1e-26 5UGG-A nrPDB 112 1e-25 4GSO-A nrPDB 112 1e-25 1FXY-A nrPDB 112 2e-25 2AIQ-A nrPDB 110 7e-25 4MPW-A nrPDB 110 7e-25 4DUR-A nrPDB 109 1e-24 5LPF-A nrPDB 107 4e-24 4E7N-A nrPDB 106 1e-23 1AE5-A nrPDB 105 1e-23 2PSX-A nrPDB 104 3e-23 3S9B-A nrPDB 104 3e-23 1PPF-E nrPDB 104 5e-23 2R0L-A nrPDB 103 5e-23 1YC0-A nrPDB 103 8e-23 1FON-A nrPDB 103 8e-23 5XRF-A nrPDB 103 9e-23 3LC3-A nrPDB 102 1e-22 1OP0-A nrPDB 102 2e-22 1EKB-B nrPDB 101 2e-22 1LTO-A nrPDB 101 3e-22 3W94-A nrPDB 100 5e-22 5TJX-A nrPDB 100 6e-22 3S69-A nrPDB 100 8e-22 5GVT-A nrPDB 100 8e-22 4DGJ-A nrPDB 99 1e-21 1SC8-U nrPDB 99 1e-21 1FIZ-A nrPDB 99 1e-21 5LHN-A nrPDB 99 2e-21 1X7A-C nrPDB 98 3e-21 1BQY-A nrPDB 98 3e-21 6I44-A nrPDB 97 6e-21 5XW8-A nrPDB 96 1e-20 2F91-A nrPDB 96 1e-20 1FIW-A nrPDB 96 2e-20 2OLG-A nrPDB 93 1e-19 4XDE-A nrPDB 92 2e-19 1KIG-H nrPDB 92 2e-19 2XXL-A nrPDB 92 2e-19 4LK4-A nrPDB 90 9e-19 1BDA-A nrPDB 89 2e-18 4Z6A-H nrPDB 88 3e-18 1C5M-D nrPDB 88 3e-18 3P8G-A nrPDB 88 4e-18 2ASU-B nrPDB 87 5e-18 3VGC-B nrPDB 87 5e-18 2F83-A nrPDB 87 7e-18 1A5I-A nrPDB 86 1e-17 1P57-B nrPDB 86 2e-17 3T2N-A nrPDB 86 2e-17 2JET-B nrPDB 85 3e-17 3DFJ-A nrPDB 85 3e-17 3E0N-B nrPDB 85 3e-17 6AOD-C nrPDB 84 4e-17 1SI5-H nrPDB 84 5e-17 5KWM-A nrPDB 84 7e-17 4IGD-A nrPDB 83 1e-16 2PKA-B nrPDB 82 2e-16 1YM0-A nrPDB 82 2e-16 2OQ5-A nrPDB 82 3e-16 1EQ9-A nrPDB 82 3e-16 4DJZ-B nrPDB 80 8e-16 2B9L-A nrPDB 78 4e-15 3F6U-H nrPDB 78 4e-15 5O32-I nrPDB 77 9e-15 2XRC-A nrPDB 75 2e-14 1M9U-A nrPDB 75 2e-14 6BQM-A nrPDB 74 6e-14 3I77-A nrPDB 74 7e-14 2HLC-A nrPDB 71 3e-13 2QY0-B nrPDB 70 7e-13 3NXP-A nrPDB 70 7e-13 2OCV-B nrPDB 70 8e-13 1GPZ-A nrPDB 70 9e-13 1VR1-H nrPDB 70 1e-12 3K65-B nrPDB 69 1e-12 3BEU-A nrPDB 69 1e-12 4BXW-A nrPDB 69 1e-12 4NZQ-A nrPDB 69 2e-12 1MKW-K nrPDB 69 2e-12 4IW4-E nrPDB 69 2e-12 1MD7-A nrPDB 69 3e-12 1ETT-H nrPDB 68 3e-12 1PQ7-A nrPDB 66 1e-11 2KAI-A nrPDB 66 1e-11 5TO3-B nrPDB 65 2e-11 4KKD-A nrPDB 65 2e-11 2FMJ-A nrPDB 65 2e-11 1ZJK-A nrPDB 64 5e-11 1Q3X-A nrPDB 64 7e-11 1ELV-A nrPDB 63 1e-10 5UBM-A nrPDB 63 1e-10 4J1Y-A nrPDB 62 3e-10 3H7T-A nrPDB 61 4e-10 1AKS-B nrPDB 60 9e-10 1EPT-B nrPDB 59 2e-09 3H7O-A nrPDB 59 2e-09 4FXG-H nrPDB 58 4e-09 1RIW-B nrPDB 54 9e-08 4X0L-C nrPDB 52 2e-07 4WJG-C nrPDB 52 3e-07 1BBR-H nrPDB 52 3e-07 3RU4-E nrPDB 49 2e-06 4F4O-C nrPDB 49 2e-06 2WIN-I nrPDB 48 5e-06 1DLE-A nrPDB 47 6e-06 2JET-C nrPDB 47 6e-06 2OK5-A nrPDB 47 6e-06 3H5C-B nrPDB 42 2e-04 3F1S-B nrPDB 42 2e-04 2I6S-A nrPDB 33 0.097 2PFE-A nrPDB 33 0.14 2EA3-A nrPDB 32 0.35 1VDW-A nrPDB 30 0.89 3SVL-A nrPDB 29 1.5 2HNT-C nrPDB 28 3.5 1BBR-E nrPDB 28 5.3 6EPE-S nrPDB 27 6.1 2HNT-F nrPDB 27 7.2 4NWK-A nrPDB 27 8.7 6C2N-A nrPDB 27 9.0 >1NN6-A nrPDB Length = 228 Score = 478 bits (1231), Expect = e-136, Method: Compositional matrix adjust. Identities = 228/228 (100%), Positives = 228/228 (100%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 140 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF 199 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN Sbjct: 181 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 228 >2RDL-A nrPDB Length = 226 Score = 344 bits (882), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 160/226 (70%), Positives = 185/226 (81%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGGTEC+PH+RPYMAYLEIVT C GFLIRRNFV+TAAHCAGRSITV LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 +EDTWQKLEV KQF HPKY+ + +DIMLLKLKEKA+LTL VGTLP ++ N +PPG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKG 201 R+CR GWGRT V +P SDTLQEVK+R++DPQAC HF DF QLCVGNP+K ++ +KG Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRNVYKG 180 Query: 202 DSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 DSGGPLLCAG+AQGI SY +AKPP+VFTRISHYRPWIN+IL+ N Sbjct: 181 DSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILREN 226 >3RP2-A nrPDB Length = 224 Score = 284 bits (727), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 134/224 (59%), Positives = 164/224 (73%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E PHSRPYMA+L+IVT G CGGFLI R FVLTAAHC GR ITV LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 + E T QK++V KQ H YN+ HDIMLLKL++K LT AV +P PS +F+ PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKG 201 MC AGWG+TGV P S TL+EV+LR+MD +AC +R +++ Q+CVG+P ++AF G Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRAAFMG 180 Query: 202 DSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 DSGGPLLCAGVA GIVSYG DAKPPA+FTR+S Y PWIN ++ Sbjct: 181 DSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVIN 224 >1EUF-A nrPDB Length = 227 Score = 246 bits (629), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 124/225 (55%), Positives = 150/225 (66%), Gaps = 2/225 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMA+L TS G S CGGFL+R +FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTS-GKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E E T Q + V + HP YN TL +DIMLLKL KA +T V + P V PG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAFK 200 MC VAGWGR GV P +D LQEV L + + C + F+++ Q+C G+P K K++F Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSFS 179 Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 GDSGGPL+C GVAQGIVSYGR+D P V+TRIS + WI+ ++ Sbjct: 180 GDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMR 224 >1FI8-A nrPDB Length = 228 Score = 242 bits (617), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 117/228 (51%), Positives = 154/228 (67%), Gaps = 2/228 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMAYL+I+ SK CGGFLIR +FVLTAAHC+G I VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E Q + V+K HP YN+ T+ +DIMLLKLK KA + AV L P + V PG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVGNPRKTKSAF 199 +C VAGWG+ G + SDTLQEV+L + + Q C + FD ++C G+P+ +++F Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 +GDSGGPL+C VA GIVSYG++D P FT++S + WI + ++ + Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 228 >1KYN-A nrPDB Length = 235 Score = 233 bits (595), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 117/226 (51%), Positives = 152/226 (67%), Gaps = 3/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E +PHSRPYMAYL+I + G S+ CGGFL+R +FVLTAAHC G +I VTLGAHNI Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSR-CGGFLVREDFVLTAAHCWGSNINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+T Q + + RHP+YN T+ +DIMLL+L + V + P + PG Sbjct: 60 QRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLM-DPQACSHFRDFDHNLQLCVGNPRKTKSAFK 200 +C VAGWGR ++ G+DTL+EV+LR+ D Q F +D Q+CVG+ R+ K+AFK Sbjct: 120 TLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFK 178 Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQA 246 GDSGGPLLC VA GIVSYG+S PP VFTR+S + PWI +++ Sbjct: 179 GDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRS 224 >1IAU-A nrPDB Length = 227 Score = 228 bits (582), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 120/226 (53%), Positives = 150/226 (66%), Gaps = 3/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMAYL ++ K CGGFLIR +FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E T Q + V + HP YN +DIMLL+L+ KA T AV L PS V PG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRD-FDHNLQLCVGNPRKTKSAF 199 + C VAGWG+T L S TLQEVK+ + + + C S R +D ++LCVG+P K++F Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 KGDSGGPL+C VAQGIVSYGR++ PP T++S + WI + ++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 225 >3TK9-A nrPDB Length = 226 Score = 218 bits (556), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 109/226 (48%), Positives = 145/226 (64%), Gaps = 4/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMA+++ + K CGG L+R++FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKS-RKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E T Q + V + HP YN ++IMLL+L+ KA T AV L PS V PG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF--RDFDHNLQLCVGNPRKTKSAF 199 ++C VAGWG + + TLQEV L + C ++ ++CVG+P+KT++ F Sbjct: 120 QLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 KGDSGGPL+C VAQGI+SYG PP V+ ++SH+ PWI + ++ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMK 224 >3G01-A nrPDB Length = 227 Score = 216 bits (549), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 111/226 (49%), Positives = 139/226 (61%), Gaps = 2/226 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E PHSRPYMAY E + G FCGGFL+R FVLTAAHC GRS+TVTLGAHNI Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 +E+T Q + V K HP YN +DIMLLKL A T AV L P + V PG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFR-DFDHNLQLCVGNPRKTKSAF 199 C VAGWG+ TL EVKL + Q C S F+ ++ ++CVG+ + ++F Sbjct: 121 DECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 +GDSGGPL+C A GIVSYG++D P VFTR+ + WI + ++ Sbjct: 181 RGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >1ORF-A nrPDB Length = 234 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 94/230 (40%), Positives = 131/230 (56%), Gaps = 15/230 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSITVTLGAHN 80 IIGG E PHSRPYM L + C G LI +++VLTAAHC + V LGAH+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 56 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 IT EE T Q + V K+F +P Y+ +T D+ LL+L EKA + V L P + + V P Sbjct: 57 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKP 116 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN-----LQLCVGNPRKT 195 G MC+VAGWGRT SDTL+EV++ ++D + C+ ++ N +C G+ R Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYGRS----DAKPPAVFTRIS-HYRPWI 240 + + GDSG PLLC GV +G+ S+G D + P V+ +S + WI Sbjct: 177 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 226 >1FDP-A nrPDB Length = 235 Score = 157 bits (396), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 88/235 (37%), Positives = 135/235 (57%), Gaps = 16/235 (6%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVT 75 G I+GG E + H+RPYMA +++ NG + CGG L+ +VL+AAHC A + V Sbjct: 6 GRILGGREAEAHARPYMASVQL---NG-AHLCGGVLVAEQWVLSAAHCLEDAADGKVQVL 61 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 LGAH++++ E + + +V++ HP T+ HD++LL+L EKA+L AV LP+ Sbjct: 62 LGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVD 121 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNP 192 V PG +C VAGWG D+LQ V L ++D C+ D + +C + Sbjct: 122 RDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESN 181 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQIL 244 R + + KGDSGGPL+C GV +G+V+ G + K P ++TR++ Y WI+ +L Sbjct: 182 R--RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1UTJ-A nrPDB Length = 242 Score = 153 bits (387), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 85/247 (34%), Positives = 133/247 (53%), Gaps = 13/247 (5%) Query: 6 LPLLLFLLCSRAEAGE---IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVL 62 + L+ LL A A E I+GG ECKP+S+P+ V+ N FCGG L+ N+V+ Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQ-----VSLNSGYHFCGGSLVNENWVV 56 Query: 63 TAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL 122 +AAHC + V LG HNI E + Q + + RHP Y++ + +DIML+KL + A+L Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATL 116 Query: 123 TLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDF 181 V + P+ + P G MC V+GWG T S+ LQ + + ++ C++ + Sbjct: 117 NTYVQPVALPT--SCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGM 174 Query: 182 DHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHYRPW 239 N C G K + +GDSGGP++C G QG+VS+G A+P P V+ ++ + W Sbjct: 175 ITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFNDW 234 Query: 240 INQILQA 246 + + + Sbjct: 235 LTSTMAS 241 >1FUJ-A nrPDB Length = 221 Score = 152 bits (385), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 93/231 (40%), Positives = 127/231 (54%), Gaps = 17/231 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVTLG 77 I+GG E +PHSRPYMA L++ + G S FCGG LI +FVLTAAHC R + V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AHN+ +E T Q V + F + Y+ +DI+L++L A+L+ +V T+ P Q Sbjct: 60 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKS 197 VP G C GWGR G P + LQE+ + ++ F HN +C PR+ Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT------FFCRPHN--ICTFVPRRKAG 170 Query: 198 AFKGDSGGPLLCAGVAQGI---VSYGRSDAKPPAVFTRISHYRPWINQILQ 245 GDSGGPL+C G+ QGI V +G + P FTR++ Y WI L+ Sbjct: 171 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1A0J-A nrPDB Length = 223 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/230 (37%), Positives = 126/230 (54%), Gaps = 11/230 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ +S Y A L+ FCGG LI +V++AAHC I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E T Q ++ +K HP YN+ L +DIML+KL + ASL V T+ PS + G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPS--SCASSG 113 Query: 142 RMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAF 199 C V+GWG +G DTL+ + L ++ +C S + + C G K + Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQAN 247 +GDSGGP++C G QG+VS+G A+ P V+T++ +YR WI+ + +N Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >4NFE-A nrPDB Length = 237 Score = 149 bits (375), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 128/244 (52%), Gaps = 26/244 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ V S+G + CGG L+ +VLTAAHC ++ V LG HN+ Sbjct: 1 IVGGWECEKHSQPWQV---AVYSHGWA-HCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 130 E EDT Q++ V F HP YN S L HD+MLL+L E A +T V L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 131 FPSQFNFVPPGRMCRVAGWGR---TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQ 186 P+Q + G C +GWG L+P S LQ V L L+ C+ + + Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRS--LQCVSLHLLSNDMCARAYSEKVTEFM 172 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQI 243 LC G K GDSGGPL+C GV QGI S+G + PAV+T++ HYR WI Sbjct: 173 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 232 Query: 244 LQAN 247 + AN Sbjct: 233 IAAN 236 >5FXL-A nrPDB Length = 246 Score = 146 bits (369), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 85/233 (36%), Positives = 124/233 (53%), Gaps = 15/233 (6%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 80 +I+GG C ++ PY L N FCGG LI +V++AAHC I V LG N Sbjct: 23 KIVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDN 77 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 I E Q + K HP YN++TL++DIML+KLK ASL V ++ P+ + Sbjct: 78 INVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCASA 135 Query: 141 GRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTK 196 G C ++GWG T G P D L+ +K ++ +C S + + C G K Sbjct: 136 GTQCLISGWGNTKSSGTSYP--DVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGK 193 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C+G QGIVS+G A+ P V+T++ +Y WI Q + +N Sbjct: 194 DSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >3BSQ-A nrPDB Length = 227 Score = 145 bits (367), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 86/231 (37%), Positives = 123/231 (53%), Gaps = 17/231 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G C S P+ ++ +G CGG L+ +VLTAAHC TV LG+ + Sbjct: 1 IIDGAPCARGSHPW----QVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 + Q+++ K FRHP Y+T T +D+ML+KL +A L+ V + PS+ PPG Sbjct: 57 GDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 112 Query: 142 RMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKS 197 C V+GWG T V P L V ++L+ PQ C+ ++D N LC G P K+ Sbjct: 113 TTCTVSGWGTTTSPDVTFPSD--LMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 170 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQ 245 A GDSGGPL+C G QG+VS+G P V+T++ + WIN ++ Sbjct: 171 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1F7Z-A nrPDB Length = 233 Score = 145 bits (366), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 92/234 (39%), Positives = 126/234 (53%), Gaps = 19/234 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY V+ N FCGG LI +V++AAHC I V LG HNI Sbjct: 11 IVGGYTCQENSVPYQ-----VSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNI 65 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K +HP ++ TL++DIML+KL L V T+ PS + P G Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPS--SCAPAG 123 Query: 142 RMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQA---CSHFRDFDHNLQLCVGNPRKT 195 C ++GWG T GV +P D LQ + L+ PQA S+ N+ +CVG Sbjct: 124 TQCLISGWGNTLSSGVNEP--DLLQCLDAPLL-PQADCEASYPGKITDNM-VCVGFLEGG 179 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQAN 247 K + +GDSGGP++C G QGIVS+G A P P V+T++ +Y WI + AN Sbjct: 180 KDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >2TLD-E nrPDB Length = 220 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 85/231 (36%), Positives = 123/231 (53%), Gaps = 16/231 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C ++ PY L N FCGG LI +V++AAHC I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K HP YN++TL++DIML+KLK ASL V ++ P+ + G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCASAG 113 Query: 142 RMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKS 197 C ++GWG T G P D L+ +K ++ +C S + + C G + Sbjct: 114 TQCLISGWGNTKSSGTSYP--DVLKCLKAPILSDSSCKSAYPGQITSNMFCAG--LEGGD 169 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRSDAK-PPAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C+G QGIVS+G AK P V+T++ +Y WI Q + +N Sbjct: 170 SCQGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTIASN 220 >4AN7-A nrPDB Length = 231 Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 89/234 (38%), Positives = 122/234 (52%), Gaps = 17/234 (7%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 80 +I+GG C +S PY L N S FCGG LI +V++AAHC I V LG HN Sbjct: 8 KIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHN 62 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 I E Q + K HP +N +TL +DIML+KL A+L V T+ P + Sbjct: 63 IDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SCAAA 120 Query: 141 GRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRKT 195 G C ++GWG T G P LQ +K ++ +C S+ N+ +CVG Sbjct: 121 GTECLISGWGNTKSSGSSYP--SLLQCLKAPVLSDSSCKSSYPGQITGNM-ICVGFLEGG 177 Query: 196 KSAFKGDSGGPLLCAGVAQGIVS--YGRSDAKPPAVFTRISHYRPWINQILQAN 247 K + +GDSGGP++C G QGIVS YG + P V+T++ +Y WI Q + AN Sbjct: 178 KDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >5C67-A nrPDB Length = 224 Score = 140 bits (354), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 88/234 (37%), Positives = 120/234 (51%), Gaps = 19/234 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY V+ N S FCGG LI +V++AAHC I V LG HNI Sbjct: 1 IVGGYTCEENSLPYQ-----VSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP- 140 E Q + K RHPKYN TL +DIML+KL A + V T+ P+ PP Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT----APPA 111 Query: 141 -GRMCRVAGWGRTGVLKPGSDTLQEVKL----RLMDPQACSHFRDFDHNLQLCVGNPRKT 195 G C ++GWG T L G+D E+K L + + + N CVG Sbjct: 112 AGTECLISGWGNT--LSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGG 169 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 K + + D+GGP++C G QG+VS+G A P V+T++ +Y WI + AN Sbjct: 170 KDSCQRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >3QUM-P nrPDB Length = 237 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 91/244 (37%), Positives = 121/244 (49%), Gaps = 26/244 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ +V S G CGG L+ +VLTAAHC + LG H++ Sbjct: 1 IVGGWECEKHSQPWQV---LVASRG-RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 130 EDT Q +V F HP Y+ S L HD+MLL+L E A LT AV + Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQ 186 P+Q + G C +GWG L P LQ V L ++ C+ Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLTP--KKLQCVDLHVISNDVCAQVHPQKVTKFM 172 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQI 243 LC G KS GDSGGPL+C GV QGI S+G + P+++T++ HYR WI Sbjct: 173 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 232 Query: 244 LQAN 247 + AN Sbjct: 233 IVAN 236 >5MS3-A nrPDB Length = 228 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 123/232 (53%), Gaps = 17/232 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG EC+PHS+P+ A L G CGG L+ N+VLTAAHC TV LG H++ Sbjct: 1 VLGGHECQPHSQPWQAAL----FQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTL---HHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 ++ Q++ V++ HP YN+S + +HD+MLL+L+++ASL V P + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKV--KPISLADHCT 114 Query: 139 PPGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKS 197 PG+ C V+GWG T + DTL ++++ + C + K Sbjct: 115 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGAD 174 Query: 198 AFKGDSGGPLLCAGVAQGIVSY-----GRSDAKPPAVFTRISHYRPWINQIL 244 +GDSGGPL+C G QGI S+ GRSD P V+T I Y WI +I+ Sbjct: 175 TCQGDSGGPLVCDGALQGITSWGSDPCGRSDK--PGVYTNICRYLDWIKKII 224 >4WWY-A nrPDB Length = 224 Score = 137 bits (345), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 86/235 (36%), Positives = 122/235 (51%), Gaps = 21/235 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY V+ N FCGG LI +V++A HC I V LG HNI Sbjct: 1 IVGGYNCEENSVPYQ-----VSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP- 140 E Q + K RHP+Y+ TL++DIML+KL +A + V T+ P+ PP Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPT----APPA 111 Query: 141 -GRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRK 194 G C ++GWG T G P D LQ + ++ C S+ N+ CVG Sbjct: 112 TGTKCLISGWGNTASSGADYP--DELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFLEG 168 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQAN 247 K + + DSGGP++C G QG+VS+G A+ P V+T++ +Y WI + AN Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1MZD-A nrPDB Length = 240 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 92/239 (38%), Positives = 130/239 (54%), Gaps = 21/239 (8%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVT 75 EIIGG E PHSRP+MA ++ G CGG LI +VLTAAHC G+S TV Sbjct: 2 EIIGGKEVSPHSRPFMASIQY----GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 57 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 LGAH++++ E + Q LE+ K + + +DIML+KL+ A L V L S+ Sbjct: 58 LGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 117 Query: 136 NFVPPGRMCRVAGWGRTG--VLKPGSDTLQEVKLRLMDPQAC---SHFRD--FDHNLQLC 188 + G C+V GWG T L+P SDTL+EV + ++ + C S++ F +C Sbjct: 118 SL-RSGTKCKVTGWGATDPDSLRP-SDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVC 175 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRS--DAKPPAVFTRIS-HYRPWINQIL 244 G+ + K + KGD+GGPL+C GV IVS G A P ++T ++ Y+ WI L Sbjct: 176 AGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1GVZ-A nrPDB Length = 237 Score = 135 bits (341), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 86/242 (35%), Positives = 126/242 (52%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG EC+ HS+P+ ++ + CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPW----QVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 130 +++EDT Q +V F P+++ S L HD+MLL+L + A +T AV L Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVL-KPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC 188 P+Q + G C +GWG GS TLQ V+LRL + C+ + + LC Sbjct: 117 LPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQ 245 + + S GDSGG L+C GV QGI S+G S D VFT++ ++ WI + ++ Sbjct: 175 ATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIE 234 Query: 246 AN 247 N Sbjct: 235 KN 236 >5FCR-A nrPDB Length = 234 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 83/238 (34%), Positives = 121/238 (50%), Gaps = 19/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GG E H+RPYMA +++ NG + CGG L+ +VL+AAHC S+ V L Sbjct: 1 ILGGQEAAAHARPYMASVQV---NG-THVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 GAH+++ E + +V HP +L D++L KL + ASL V LP + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS----HFRDFDHNLQLCVGNP 192 V PG +C VAGWG D L ++++ +M+ C+ H N+ N Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNR 176 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 R T +GDSG PL+C +G+V++G + K P V+TR+S YR WI I N Sbjct: 177 RDT---CRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >1SPJ-A nrPDB Length = 238 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 129/247 (52%), Gaps = 31/247 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ A L ++ CGG L+ R +VLTAAHC + + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ----CGGILVHRQWVLTAAHCISDNYQLWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKA-SLTLAVGTL 129 ++E+T Q + V + F HP +N S L HD+MLL+L E A ++T AV + Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 130 PFPSQFNFVPPGRMCRVAGWGRTGVLKPGS----DTLQEVKLRLMDPQAC--SHFRDFDH 183 P++ V G C +GWG ++P + D LQ V L+++ C +H + Sbjct: 117 ELPTEEPEV--GSTCLASGWGS---IEPENFSFPDDLQCVDLKILPNDECKKAHVQKVT- 170 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWI 240 + LCVG+ K GDSGGPL+C GV QG+ S+G P+V R+ Y WI Sbjct: 171 DFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWI 230 Query: 241 NQILQAN 247 + N Sbjct: 231 EDTIAEN 237 >4Q7Y-A nrPDB Length = 250 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 89/234 (38%), Positives = 120/234 (51%), Gaps = 14/234 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTLG 77 IIGG E PHSRPYMA + G CGGFL+R +V++AAHC R+ V LG Sbjct: 1 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AH ++ E T Q + HP Y+ T +DI LL+L A L AVG L P + Sbjct: 57 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRAR 116 Query: 138 VP-PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKT 195 P G CRVAGWG + L E K+R++DP C S ++ LC + Sbjct: 117 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 176 Query: 196 KSAF-KGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQ 245 + F DSGGPL+C A G+VS+ D K P V+T++S + WI +++ Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 230 >2EEK-A nrPDB Length = 220 Score = 133 bits (334), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 74/226 (32%), Positives = 117/226 (51%), Gaps = 10/226 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC HS+ + V+ N FCGG L+ +++V++AAHC + V LG H+I Sbjct: 1 IVGGYECTKHSQAHQ-----VSLNSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E T Q + RHP Y++ +++DIML+KL + A+L V + P++ Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTE--CAADA 113 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFK 200 MC V+GWG T D LQ + L ++ C++ + C G K + + Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 201 GDSGGPLLCAGVAQGIVS--YGRSDAKPPAVFTRISHYRPWINQIL 244 GDSGGP++C GV QG+VS YG ++ P V+ ++ W+ + Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >5ZFH-A nrPDB Length = 224 Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 117/233 (50%), Gaps = 17/233 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G +CK S P+ ++ G CGG L+ + +VLTAAHC V LG+ I Sbjct: 1 IIDGYKCKEGSHPW----QVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKI 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 ++ QK++ K FRHP Y+T T +DIML++L E ++ V + P PPG Sbjct: 57 GDQSA--QKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPG 112 Query: 142 RMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKS 197 C V+GWG T V P +VKL + + C ++D LC G P + Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKL--ISSRECKKVYKDLLGKTMLCAGIPDSKTN 170 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C QG+VS+G P V+T++ Y+ W+ + ++ + Sbjct: 171 TCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >1ELT-A nrPDB Length = 236 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 81/238 (34%), Positives = 119/238 (50%), Gaps = 17/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 ++GG +P+S P+ L+ + + CGG LIR+ +V+TAAHC + R+ V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 N+ E Q + V F H +N+ + +DI LL+L +ASL AV P Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRK 194 +P C + GWG+T P SD+L++ L +D CS + ++ +C G Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG--G 178 Query: 195 TKSAFKGDSGGPLLCA--------GVAQGIVSYGRSDAKPPAVFTRISHYRPWINQIL 244 S GDSGGPL C GV + S G + +K P VFTR+S Y W+N I+ Sbjct: 179 ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >2BDH-A nrPDB Length = 223 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 122/232 (52%), Gaps = 16/232 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G +C PHS+P+ A L V N FC G L+ +VL+AAHC S T+ LG H++ Sbjct: 1 IINGEDCSPHSQPWQAAL--VMEN--ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 56 Query: 82 -TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ++E Q +E RHP+YN L +D+ML+KL E S + + ++ SQ Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-- 114 Query: 141 GRMCRVAGWGRTGVLKPGS--DTLQEVKLRLMDPQACSHFRD-FDHNLQLCVGNPRKTKS 197 G C V+GWG +L G LQ V + ++ + CS D H C G + K Sbjct: 115 GNSCLVSGWG---LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKD 171 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQA 246 + GDSGGPL+C G QG+VS+G++ P V+T + + WI + +QA Sbjct: 172 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >1PYT-D nrPDB Length = 251 Score = 127 bits (320), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 120/242 (49%), Gaps = 17/242 (7%) Query: 19 AGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT--VTL 76 + ++GG + PHS P+ L+ + N CGG LI N VLTAAHC ++T V L Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVAL 70 Query: 77 GAHNI-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 G +N+ E+E + V F H K+N+ + +DI L+KL E L + PS+ Sbjct: 71 GKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEG 130 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF----DHNLQLCVGN 191 + +P C V GWGR P + LQ+ ++D CS RD+ +C G Sbjct: 131 SLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQ-RDWWGTTVKETMVCAGG 189 Query: 192 PRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGR----SDAKPPAVFTRISHYRPWINQI 243 SA GDSGGPL C Q GIVS+G + K P VFTR+S Y WINQ Sbjct: 190 -DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQK 248 Query: 244 LQ 245 LQ Sbjct: 249 LQ 250 >2V35-A nrPDB Length = 240 Score = 127 bits (319), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 80/241 (33%), Positives = 120/241 (49%), Gaps = 16/241 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT--VTLGAH 79 ++GGTE + +S P L+ + + + CGG LIR+N+V+TAAHC R +T V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 N+ + + T Q + V K HP +NT + +DI LL+L + +L V P Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC---SHFRDFDHNLQLCVGNPRK 194 + C + GWG T + TLQ+ L +D C S++ N +C G Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGD-G 179 Query: 195 TKSAFKGDSGGPLLCA--------GVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQA 246 +S +GDSGGPL C GV + G + + P VFTR+S Y WIN ++ + Sbjct: 180 VRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIAS 239 Query: 247 N 247 N Sbjct: 240 N 240 >1BRU-P nrPDB Length = 241 Score = 126 bits (317), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 82/242 (33%), Positives = 124/242 (51%), Gaps = 17/242 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 ++GG + +P+S P+ L+ +S CGG L+ +++VLTAAHC + R+ V LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 +++ E ++V K H +N++ L +DI LLKL SLT + P+ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRK 194 +P +C V GWGR D LQ+ +L ++D CS + ++ +C G Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG-DG 179 Query: 195 TKSAFKGDSGGPLLCAGV-----AQGIVSYGRSDA----KPPAVFTRISHYRPWINQILQ 245 S+ GDSGGPL C G GIVS+G S P+VFTR+S+Y WIN ++ Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIA 239 Query: 246 AN 247 N Sbjct: 240 NN 241 >2CGA-A nrPDB Length = 245 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 82/235 (34%), Positives = 113/235 (48%), Gaps = 14/235 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSITVTLGAHN 80 I+ G E P S P+ L+ T FCGG LI N+V+TAAHC S V G + Sbjct: 16 IVNGEEAVPGSWPWQVSLQDKTG---FHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 72 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + QKL++ K F++ KYN+ T+++DI LLKL AS + V + PS + Sbjct: 73 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 132 Query: 141 GRMCRVAGWGRTGVLKPGS-DTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRKTKSA 198 G C GWG T + D LQ+ L L+ C + + +C G S+ Sbjct: 133 GTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSS 190 Query: 199 FKGDSGGPLLC----AGVAQGIVSYGRS--DAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C A GIVS+G S P V+ R++ W+ Q L AN Sbjct: 191 CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 245 >1TON-A nrPDB Length = 235 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 127/242 (52%), Gaps = 24/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG +C+ +S+P+ ++ N CGG LI ++V+TAAHC + V LG +N+ Sbjct: 1 IVGGYKCEKNSQPW----QVAVIN--EYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNL 54 Query: 82 TEEEDTWQKLEVIKQFRHPKY-------NTSTLHH----DIMLLKLKEKASLTLAVGTLP 130 ++E Q+ V + FRHP Y +T H D+MLL L E A +T V + Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLC 188 P++ V G C +GWG T + S LQ V + L+ + C ++D ++ LC Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQILQ 245 G K GDSGGPL+C GV QGI S G + AKP PA++ ++ + WI ++++ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 246 AN 247 N Sbjct: 233 EN 234 >4H4F-A nrPDB Length = 249 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 81/239 (33%), Positives = 121/239 (50%), Gaps = 16/239 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 79 ++GG + +PHS P+ L+ + ++ CGG LI NFVLTAAHC R+ V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 80 NI-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 N+ E+E+ + V H ++N L +DI L+KL E L+ + P + + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 139 PPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRKT 195 P C V GWGR P +D LQ+ ++D CS + ++ +C G Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD-GV 179 Query: 196 KSAFKGDSGGPLLC-----AGVAQGIVSYGR----SDAKPPAVFTRISHYRPWINQILQ 245 SA GDSGGPL C + GIVS+G + K P V+TR+S Y WIN+ +Q Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >2ZKS-A nrPDB Length = 240 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 123/234 (52%), Gaps = 19/234 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT---VTLGA 78 IIGG E PHSRPYMA L+ NG S CGG L+ +VLTAAHC + + + LG Sbjct: 1 IIGGREVIPHSRPYMASLQ---RNG-SHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 H + T+ + +HP+Y L +D+ LL+L K + + L PS+ Sbjct: 57 HTLDSPGLTFH---IKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQV 113 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRK 194 V G C +AGWG T S L+E+ L+++D + C++ R ++ +L +C+ K Sbjct: 114 VAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 173 Query: 195 TKSAFKGDSGGPLLCAG--VAQGIVSYGR---SDAKPPAVFTRISHYRPWINQI 243 ++ KGDSGGPL+C V G++S+ +D P V T ++ Y WI ++ Sbjct: 174 DQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 227 >1NPM-A nrPDB Length = 225 Score = 120 bits (301), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 81/235 (34%), Positives = 122/235 (51%), Gaps = 23/235 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+ G EC PHS+P+ A L G CGG L+ +VLTAAHC + +V LG H++ Sbjct: 1 ILEGRECIPHSQPWQAAL----FQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH---HDIMLLKLKEKASLTLAVGTLPFPSQF-NF 137 + Q+++V + +HP YN S HDIML++L+ A+L G P Q N Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANL----GDKVKPVQLANL 112 Query: 138 VPP-GRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QLCVGNP 192 P G+ C ++GWG T + +TL ++++ C R + + +C G+ Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCE--RAYPGKITEGMVCAGSS 170 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQIL 244 + +GDSGGPL+C G+ QGI S+G KP P V+T+I Y WI + + Sbjct: 171 NGADTC-QGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1SGF-G nrPDB Length = 237 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 122/243 (50%), Gaps = 24/243 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG +C+ +S+P+ + T CGG L+ N+VLTAAHC + V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQ----YLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 130 ++E + Q V K HP +N S + +D+MLL+L + A +T V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQL 187 P++ + G C +GWG K +D L V L+L+ + C +H + L Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVT-DAML 173 Query: 188 CVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQIL 244 C G K KGDSGGPL+C GV QGI S+G + + P V+T+++ + WI + Sbjct: 174 CAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTM 233 Query: 245 QAN 247 N Sbjct: 234 AKN 236 >1AO5-A nrPDB Length = 237 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/244 (33%), Positives = 119/244 (48%), Gaps = 26/244 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG C+ +S+P+ ++ CGG L+ RN+VLTAAHC V LG + + Sbjct: 1 VVGGFNCEKNSQPW----QVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGTLP 130 +EE + Q V K F HP +N S L D+MLL+L + A +T V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 131 FPSQFNFVPPGRMCRVAGWGR---TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQ 186 P++ PG C +GWG T KP D LQ V + L+ + C+ + ++ Sbjct: 117 LPTKEP--KPGSKCLASGWGSITPTRWQKP--DDLQCVFITLLPNENCAKVYLQKVTDVM 172 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQI 243 LC G K + DSGGPL+C G+ QG SYG KP PA++T + + WI Sbjct: 173 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 232 Query: 244 LQAN 247 + N Sbjct: 233 MMKN 236 >6QHB-A nrPDB Length = 223 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 118/230 (51%), Gaps = 13/230 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++ G C S PY A L TS CGG LI +VLTAAHC ++ V LG HN+ Sbjct: 1 LVHGGPCDKTSHPYQAAL--YTSG--HLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 ++E + ++ V++ HP Y+ ++ DIMLL+L A L+ + P P + + Sbjct: 57 GQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELI--QPLPLERDCSAQT 114 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR--DFDHNLQLCVGNPRKTKSAF 199 C + GWG+T DT+Q + L+ + C H N+ LC G+ + K + Sbjct: 115 TSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAYPGQITQNM-LCAGDEKYGKDSC 172 Query: 200 KGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQA 246 +GDSGGPL+C +G+VS+G + P V+T + Y WI + +QA Sbjct: 173 QGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 222 >1AZZ-A nrPDB Length = 226 Score = 117 bits (294), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 77/225 (34%), Positives = 113/225 (50%), Gaps = 13/225 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS--ITVTLGAH 79 I+GG E P+S P+ A L I FCGG LI ++LTAAHC + + V LGAH Sbjct: 1 IVGGVEAVPNSWPHQAALFI----DDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NI E+E T ++ H YN+ + +DI +++L +LT A+ T+ PS V Sbjct: 57 NIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPS--TDVG 114 Query: 140 PGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSA 198 G + GWG G SD L++V + +M C + +C+ + K Sbjct: 115 VGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICI-DSTGGKGT 173 Query: 199 FKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWI 240 GDSGGPL G+ GI S+G + +A P FTR++++ WI Sbjct: 174 CNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWI 218 >1SGF-A nrPDB Length = 240 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 72/213 (33%), Positives = 107/213 (50%), Gaps = 18/213 (8%) Query: 51 CGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLH-- 108 CGG L+ RN+VLTAAHC V LG +N E+E + Q V K HP +N S L+ Sbjct: 29 CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEH 88 Query: 109 ---------HDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLK-PG 158 +D+MLL+L + A +T V + P++ + G C +GWG T +K Sbjct: 89 TPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL--GSTCLASGWGSTTPIKFKY 146 Query: 159 SDTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIV 217 D LQ V L+L+ + C + + LC G + DSGGPL+C G+ QGI Sbjct: 147 PDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGIT 206 Query: 218 SYGRS---DAKPPAVFTRISHYRPWINQILQAN 247 S+G + P+V+T++ + WI + + N Sbjct: 207 SWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >5UGG-A nrPDB Length = 251 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 83/243 (34%), Positives = 118/243 (48%), Gaps = 26/243 (10%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGR-----SITV 74 G ++GG PHS P+ L T G FCGG LI +VLTAAHC + S V Sbjct: 20 GRVVGGCVAHPHSWPWQVSLR--TRFG-MHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 76 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGAH E Q++EV + F P DI LLKL A +T V PS Sbjct: 77 ILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSP 130 Query: 135 FNFVPPGRMCRVAGWGRT-GVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVG 190 V C + GWG T G G+ L+E +L +++ + C+ + + +Q LC G Sbjct: 131 NYVVADRTECFITGWGETQGTF--GAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAG 188 Query: 191 NPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQIL 244 + + +GDSGGPL+C + QG+ S+G A+P P V+ R+S + WI ++ Sbjct: 189 HLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 248 Query: 245 QAN 247 + N Sbjct: 249 RNN 251 >4GSO-A nrPDB Length = 232 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 80/237 (33%), Positives = 113/237 (47%), Gaps = 23/237 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN- 80 ++GG EC + P++A+L S+G FCG LI + +V+TAAHC + + LG H+ Sbjct: 1 VLGGDECDINEHPFLAFL---YSHG--YFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSK 55 Query: 81 --ITEEEDTWQKLEVIKQFRHPKYNTS-TLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 + E+E T E +F P N S L DIML+KL + S + + L PS Sbjct: 56 KVLNEDEQTRNPKE---KFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSN--- 109 Query: 138 VPP--GRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNPR 193 PP G +CR+ GWG + D + L+D + C + LC G Sbjct: 110 -PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLE 168 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 K GDSGGPL+C G QGIVSYG P ++T + Y WI + + N Sbjct: 169 GGKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >1FXY-A nrPDB Length = 228 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/237 (32%), Positives = 114/237 (48%), Gaps = 21/237 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 I+GG CK P+ A L + G FCGG ++ ++LTAAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 N +EE EV +H ++ T DI +L+LK + + V P+ P Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPT----AP 113 Query: 140 P--GRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNP 192 P G C ++GWG T G P D LQ + ++ C S+ N+ CVG Sbjct: 114 PATGTKCLISGWGNTASSGADYP--DELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFL 170 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQAN 247 K + +GDSGGP++C G QG+VS+G A+ P V+T++ +Y WI + AN Sbjct: 171 EGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >2AIQ-A nrPDB Length = 231 Score = 110 bits (274), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 76/236 (32%), Positives = 113/236 (47%), Gaps = 22/236 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 +IGG EC + ++A +V +NG CGG LI + +VLTA HC ++ + LG HN+ Sbjct: 1 VIGGDECNINEHRFLA---LVYANG--SLCGGTLINQEWVLTARHCDRGNMRIYLGMHNL 55 Query: 82 -TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 +D ++ K F N + DIML++L + + L PS PP Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSN----PP 111 Query: 141 --GRMCRVAGWGRTGVLKPGSDTLQEV----KLRLMDPQACSHFRDFDHNLQLCVGNPRK 194 G +CR+ GWG + P + TL +V + ++D C LC G Sbjct: 112 SVGSVCRIMGWGT--ITSPNA-TLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEG 168 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 K KGDSGGPL+C G QGI+S G + + P ++T++ Y WI I+ N Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >4MPW-A nrPDB Length = 245 Score = 110 bits (274), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 122/249 (48%), Gaps = 34/249 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPS--KFCGGFLIRRNFVLTAAHCAGRSIT------ 73 I+GG E P+ L + +GP FCGG LI +VLTAAHC G + Sbjct: 1 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 57 Query: 74 VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 V L ++ ++ Q L V + HP++ T+ + DI LL+L+E ++ V T+ P Sbjct: 58 VQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPP 114 Query: 134 QFNFVPPGRMCRVAGWGRTGVLK--PGSDTLQEVKLRLMDPQACS---HFRDFD------ 182 PPG C V GWG + P L++VK+ +M+ C H + Sbjct: 115 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 174 Query: 183 -HNLQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISH 235 + LC GN R + + +GDSGGPL+C + G+VS+G A+P P ++TR+++ Sbjct: 175 VRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 232 Query: 236 YRPWINQIL 244 Y WI+ + Sbjct: 233 YLDWIHHYV 241 >4DUR-A nrPDB Length = 791 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/243 (33%), Positives = 116/243 (47%), Gaps = 26/243 (10%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGR-----SITV 74 G ++GG PHS P+ L FCGG LI +VLTAAHC + S V Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 616 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGAH E Q++EV + F P DI LLKL A +T V PS Sbjct: 617 ILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSP 670 Query: 135 FNFVPPGRMCRVAGWGRT-GVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVG 190 V C + GWG T G G+ L+E +L +++ + C+ + + +Q LC G Sbjct: 671 NYVVADRTECFITGWGETQGTF--GAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAG 728 Query: 191 NPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQIL 244 + + +GDSGGPL+C + QG+ S+G A+P P V+ R+S + WI ++ Sbjct: 729 HLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 788 Query: 245 QAN 247 + N Sbjct: 789 RNN 791 >5LPF-A nrPDB Length = 234 Score = 107 bits (267), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 115/236 (48%), Gaps = 21/236 (8%) Query: 25 GTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEE 84 G+ C S+P+ ++ NG S C G L+ +++VLTAAHC + + +G ++ Sbjct: 7 GSPCARGSQPW----QVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLL 62 Query: 85 EDTWQKLEVIKQFRHPKYNTS--------TLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 + Q + HPKY+ T HD+MLLKL L V L P + Sbjct: 63 QGE-QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLP--YR 119 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDT-LQEVKLRLMDPQACSHFR-DFDHNLQLCVGNPRK 194 PG C+VAGWG T + + L + ++ P+ C F N +C G R Sbjct: 120 CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRG 179 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 + + DSGGPL+C QGI+S+G A+ PAV+T+I Y WIN+++++N Sbjct: 180 -QDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >4E7N-A nrPDB Length = 238 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/238 (33%), Positives = 117/238 (49%), Gaps = 19/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN- 80 IIGG EC + ++ L TS + FCGG LI + +VLTAAHC ++ + LG H+ Sbjct: 1 IIGGDECNINEHRFLVAL--YTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSK 58 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ED ++ K F N + DIML++L + + PS V Sbjct: 59 KVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSV-- 116 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQE----VKLRLMDPQAC-SHFRDFD---HNLQLCVGNP 192 G +CR+ GWGR + P T + V + L++ + C + + +F+ + LC G Sbjct: 117 GSVCRIMGWGR---ISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGIL 173 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQILQAN 247 K KGDSGGPL+C G QGI S+G A+P PA +T++ + WI I+ N Sbjct: 174 EGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGN 231 >1AE5-A nrPDB Length = 225 Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 73/230 (31%), Positives = 109/230 (47%), Gaps = 18/230 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTL 76 I+GG + +P P++A ++ N FCGG LI FV+TAA C G S TV L Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVL 55 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 GA+++ E ++ I Y+ +D+MLL+L +A+LT +V LP P Q Sbjct: 56 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 115 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTK 196 V G C+VAGWG S + V + + C +C G + Sbjct: 116 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------RPNNVCTGVLTRRG 168 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYGRSD-AKPPAVFTRISHYRPWINQILQ 245 GD G PL+C G+A G+ S+ + P FTR++ +R WI+ +L Sbjct: 169 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 218 >2PSX-A nrPDB Length = 227 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 70/233 (30%), Positives = 123/233 (52%), Gaps = 14/233 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G++C H++P+ A L + + +CG L+ ++LTAAHC + V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQ---LYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSL 57 Query: 82 TEEEDTWQKL-EVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + ++ Q++ + +K HP Y+ +D+ML+KL + T V P + Sbjct: 58 SPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDV--RPINVSSHCPSA 115 Query: 141 GRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRKTKS 197 G C V+GWG T + LQ + + ++ + C ++ R D + C G+ + + Sbjct: 116 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTM-FCAGD-KAGRD 173 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C G QG+VS+G A+P P V+T + + WI + +QAN Sbjct: 174 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3S9B-A nrPDB Length = 234 Score = 104 bits (259), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 109/234 (46%), Gaps = 15/234 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG EC + P++ L TS + C G LI R +VLTAAHC R+I + LG H+ Sbjct: 1 VVGGDECNINEHPFLVAL--YTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSK 58 Query: 82 T-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ED ++ K F + L DIML++L+ + + + + PS+ V Sbjct: 59 NIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV-- 116 Query: 141 GRMCRVAGWGRTGVLK----PGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTK 196 G CR+ GWG+ P + VK + +P D + LC G + + Sbjct: 117 GSRCRIMGWGKISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPAD---SRTLCAGILKGGR 173 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYGRSDAK---PPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C G GIV+ G PAV+T++ Y WI I+ N Sbjct: 174 DTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >1PPF-E nrPDB Length = 218 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 30/236 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVT----LG 77 I+GG +PH+ P+M L++ + FCG LI NFV++AAHC LG Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGH----FCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AHN++ E T Q V + F + Y+ L +DI++L+L A++ V P+Q Sbjct: 57 AHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 115 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMD-----PQACSHFRDFDHNLQLCVGNP 192 + G C GWG G + + LQE+ + ++ C+ R Sbjct: 116 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRG------------ 163 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP---PAVFTRISHYRPWINQILQ 245 R+ F GDSG PL+C G+ GI S+ R P F ++ + WI+ I+Q Sbjct: 164 RQAGVCF-GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >2R0L-A nrPDB Length = 248 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 120/244 (49%), Gaps = 25/244 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITVTL 76 IIGG+ P S P++A + I S FC G L+ +V++AAHC S ++V L Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNT-STLHHDIMLLKLKEK----ASLTLAVGTLPF 131 G H D Q + K + Y+ + HD++L++LK+K A+ + V + Sbjct: 56 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 115 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSHFRDFDHNLQ---L 187 P + P G C++AGWG G S +L+E + L+ CS + ++ L Sbjct: 116 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 175 Query: 188 CVGNPRKTKSAFKGDSGGPLLCA--GVA--QGIVSYGRSDAK--PPAVFTRISHYRPWIN 241 C G A +GDSGGPL C GVA GI+S+G + P V+TR+++Y WIN Sbjct: 176 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 235 Query: 242 QILQ 245 ++ Sbjct: 236 DRIR 239 >1YC0-A nrPDB Length = 283 Score = 103 bits (256), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 120/245 (48%), Gaps = 25/245 (10%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITVT 75 IIGG+ P S P++A + I S FC G L+ +V++AAHC S ++V Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS-----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVV 89 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNT-STLHHDIMLLKLKEK----ASLTLAVGTLP 130 LG H D Q + K + Y+ + HD++L++LK+K A+ + V + Sbjct: 90 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 149 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSHFRDFDHNLQ--- 186 P + P G C++AGWG G S +L+E + L+ CS + ++ Sbjct: 150 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 209 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCA--GVA--QGIVSYGRSDAK--PPAVFTRISHYRPWI 240 LC G A +GDSGGPL C GVA GI+S+G + P V+TR+++Y WI Sbjct: 210 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 269 Query: 241 NQILQ 245 N ++ Sbjct: 270 NDRIR 274 >1FON-A nrPDB Length = 240 Score = 103 bits (256), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 72/241 (29%), Positives = 115/241 (47%), Gaps = 20/241 (8%) Query: 25 GTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAHNIT 82 G + P+S + L+ CGG LI ++V+TA HC R+ V LG ++ + Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRS 61 Query: 83 EEEDTWQKLEVIKQ--FRHPKYNTSTLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 E + Q + + F HP +N++ + +DI L+KL A L V P + + Sbjct: 62 VLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDIL 121 Query: 139 PPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRKT 195 P C ++GWGR P D LQ+ L +D + CS + + ++ +C G T Sbjct: 122 PNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG--DT 179 Query: 196 KSAFKGDSGGPLLCA---------GVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQA 246 +S GDSGGPL C GV + ++G + K P VFTR+S + WI++ + + Sbjct: 180 RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIAS 239 Query: 247 N 247 N Sbjct: 240 N 240 >5XRF-A nrPDB Length = 242 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 113/233 (48%), Gaps = 17/233 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 +IGG EC + ++A TS + C G LI +VL AAHC R + + LG HN Sbjct: 7 VIGGNECDTNEHRFLA--AFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQ 64 Query: 82 TEEEDTWQKLEVIKQ-FRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + + D Q+ I++ + + D++LLKL + S + + L PS + Sbjct: 65 SIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSI-- 122 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEV----KLRLMDPQAC-SHFRDFDHNLQ-LCVGNPRK 194 G +CRV GW G++ D L +V + L++ C +H+ D + LC G Sbjct: 123 GSVCRVMGW---GIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEG 179 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQIL 244 DSGGPL+C G QGIV +G+ + P ++TR+S+Y WI I+ Sbjct: 180 GIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >3LC3-A nrPDB Length = 235 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 109/234 (46%), Gaps = 17/234 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 ++GG + KP P+ ++V + FCGG ++ +++TAAHC G ITV G H Sbjct: 1 VVGGEDAKPGQFPW----QVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEH 56 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTST--LHHDIMLLKLKEKASLTLAVGTLPFPSQ--F 135 NI E E T QK VI+ H YN + +HDI LL+L E L V + + Sbjct: 57 NIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYT 116 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRK 194 N V+GWGR + LQ +++ L+D C F +N C G Sbjct: 117 NIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEG 176 Query: 195 TKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWINQ 242 + + +GDSGGP + GI+S+G A ++T++S Y WI + Sbjct: 177 GRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 230 >1OP0-A nrPDB Length = 234 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 110/239 (46%), Gaps = 25/239 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN- 80 +IGG EC + ++ + N FCGG LI +V+TAAHC + LG H+ Sbjct: 1 VIGGNECDINEHRFL----VAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSK 56 Query: 81 --ITEEEDTWQKLEVIKQFRHP-KYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 + E+E T E +F P K N L DIML+KL + S + + L PS Sbjct: 57 KVLNEDEQTRNPKE---KFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPS 113 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEV----KLRLMDPQACS--HFRDFDHNLQLCVGN 191 V G +CR+ GWG + P +T +V + L+D C + LC G Sbjct: 114 V--GSVCRIMGWGS---ITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGI 168 Query: 192 PRKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 + K GDSGGPL+C G QGIVSYG P ++T + Y WI + + N Sbjct: 169 VQGGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >1EKB-B nrPDB Length = 235 Score = 101 bits (252), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 113/239 (47%), Gaps = 21/239 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSIT-----VT 75 I+GG++ + + P++ L + CG L+ R+++++AAHC GR++ Sbjct: 1 IVGGSDSREGAWPWVVALYF----DDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 76 LGAHNITEEEDTWQKLEVIKQFR-HPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LG H + + +I Q +P YN ++DI ++ L+ K + T + + P + Sbjct: 57 LGLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEE 116 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH---FRDFDHNLQLCVGN 191 PPGR+C +AGWG +D LQE + L+ + C + N+ +C G Sbjct: 117 NQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENM-VCAGY 175 Query: 192 PRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQIL 244 + +GDSGGPL+C + G+ S+G A P P V+ R+ + WI L Sbjct: 176 EAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFL 234 >1LTO-A nrPDB Length = 245 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 115/247 (46%), Gaps = 30/247 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT------VT 75 I+GG E P+ L V FCGG LI +VLTAAHC G + V Sbjct: 1 IVGGQEAPRSKWPWQVSLR-VRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQ 59 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 L ++ ++ Q L V + HP++ DI LL+L+E +++ V T+ P Sbjct: 60 LREQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPAS 116 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSD--TLQEVKLRLMDPQACS---HFRDFD-------H 183 PPG C V GWG +P L++VK+ +M+ C H + Sbjct: 117 ETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIR 176 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYR 237 + LC GN + + KGDSGGPL+C + G+VS+ A+P P ++TR+++Y Sbjct: 177 DDMLCAGN--SQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYL 234 Query: 238 PWINQIL 244 WI+ + Sbjct: 235 DWIHHYV 241 >3W94-A nrPDB Length = 235 Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 114/239 (47%), Gaps = 25/239 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSI-----TVT 75 ++GG + + P+M L +G CG LI R+++LTAAHC G++ + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHG----CGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 76 LGAH---NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFP 132 LG H ++ +E Q +V + + YN T DI ++ L++ + T V + Sbjct: 57 LGLHAQSSMNSQEV--QIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLA 114 Query: 133 SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQLCV 189 S+ P GR C +AGWGR D LQE ++ L+D C F ++ LC Sbjct: 115 SEDQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSM-LCA 173 Query: 190 GNPRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAKP--PAVFTRISHYRPWINQ 242 G P + +GDSGGPL+C A+ G+ S+G +P P + R+S + WI + Sbjct: 174 GYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAE 232 >5TJX-A nrPDB Length = 263 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 119/251 (47%), Gaps = 20/251 (7%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----- 67 +C+ + I+GGTE P+ L++ + CGG LI +VLTAAHC Sbjct: 7 VCTTKTSTRIVGGTESSWGEWPWQVSLQVKLT-AQRHLCGGSLIGHQWVLTAAHCFDGLP 65 Query: 68 ---AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTL 124 R + L +IT++ Q E+I H Y S +HDI L+KL+ T Sbjct: 66 LQDVWRIYSGILELSDITKDTPFSQIKEII---IHQNYKVSEGNHDIALIKLQAPLEYTE 122 Query: 125 AVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDH 183 + PS+ + C V GWG + + LQ+V + L+ + C ++D+ Sbjct: 123 FQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI 182 Query: 184 NLQL-CVGNPRKTKSAFKGDSGGPLLCA--GVAQ--GIVSYGRSDAK--PPAVFTRISHY 236 ++ C G K A KGDSGGPL+C G+ + GI S+G A+ P V+T+++ Y Sbjct: 183 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 242 Query: 237 RPWINQILQAN 247 WI + Q++ Sbjct: 243 MDWILEKTQSS 253 >3S69-A nrPDB Length = 234 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 80/237 (33%), Positives = 107/237 (45%), Gaps = 21/237 (8%) Query: 22 IIGGTECKPHS-RPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 80 +IGG EC + R +A+ N FC G LI +VLTAAHC + + LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFF-----NSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHS 55 Query: 81 ---ITEEEDTWQKLEVIKQFRHP-KYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 + E+E T E +F P K N L DIML+KL + S + + L PS Sbjct: 56 KKVLNEDEQTRNPKE---KFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPP 112 Query: 137 FVPPGRMCRVAGWGRTGVLKPGS-DTLQEVKLRLMDPQACS--HFRDFDHNLQLCVGNPR 193 V G +C + GWG +K D + L+D C + LC G Sbjct: 113 SV--GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 K GDSGGPL+C G QGIVS+G P V+T++ Y WI I+ N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >5GVT-A nrPDB Length = 250 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 77/242 (31%), Positives = 116/242 (47%), Gaps = 20/242 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--------AGRSIT 73 I+GGT P+ L++ + + CGG +I R +VLTAAHC R Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVS-QTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 74 VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 L IT+E + + E+I H +Y S ++DI L+KL+ + T + PS Sbjct: 60 GILSLSEITKETPSSRIKELI---IHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPS 116 Query: 134 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQL-CVGN 191 + + C V GWG T + LQ+ + L+ + C +RD+ N Q+ C G Sbjct: 117 KADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGY 176 Query: 192 PRKTKSAFKGDSGGPLLC--AGVAQ--GIVSYGRSDAKP--PAVFTRISHYRPWINQILQ 245 A KGDSGGPL+C +G Q GI S+G A+ P V+T++S Y WI + Q Sbjct: 177 KEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQ 236 Query: 246 AN 247 ++ Sbjct: 237 SS 238 >4DGJ-A nrPDB Length = 235 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 69/242 (28%), Positives = 114/242 (47%), Gaps = 25/242 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSI-----TVT 75 I+GG++ K + P++ L CG L+ +++++AAHC GR++ T Sbjct: 1 IVGGSDAKEGAWPWVVGLYY----DDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 76 LGAH---NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFP 132 LG H N+T + + ++ I +P YN +DI ++ L+ K + T + + P Sbjct: 57 LGLHMKSNLTSPQTVPRLIDEI--VINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLP 114 Query: 133 SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH---FRDFDHNLQLCV 189 + PPGR C +AGWG +D LQE + L+ + C + N+ +C Sbjct: 115 EENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENM-ICA 173 Query: 190 GNPRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAKP--PAVFTRISHYRPWINQI 243 G + +GDSGGPL+C + G+ S+G A P P V+ R+S + WI Sbjct: 174 GYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQSF 233 Query: 244 LQ 245 L Sbjct: 234 LH 235 >1SC8-U nrPDB Length = 262 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 75/244 (30%), Positives = 115/244 (47%), Gaps = 26/244 (10%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKF-CGGFLIRRNFVLTAAHC-----AGRSITV 74 +IIGG ++P+ A + G + CGG LI +V++A HC V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTL--HHDIMLLKLKEK----ASLTLAVGT 128 LG + K EV H Y+ TL H+DI LLK++ K A + + T Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 129 LPFPSQFNFVPPGRMCRVAGWGR---TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL 185 + PS +N G C + G+G+ T L P + L+ ++L+ + C + + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYP--EQLKMTVVKLISHRECQQPHYYGSEV 192 Query: 186 ---QLCVGNPRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDA--KPPAVFTRISHY 236 LC +P+ + +GDSGGPL+C+ + GIVS+GR A P V+TR+SH+ Sbjct: 193 TTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHF 252 Query: 237 RPWI 240 PWI Sbjct: 253 LPWI 256 >1FIZ-A nrPDB Length = 263 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 120/252 (47%), Gaps = 27/252 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKF--CGGFLIRRNFVLTAAHCAGRSITVT---- 75 ++GG +P + P+M L+I + ++ CGG L+ ++VLTAAHC VT Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 76 -LGAHNITEEEDTWQKLEVIKQFR-----HPKYNTSTLHHDIMLLKLKEKASLTLAVGTL 129 GA+ + + K + ++F H KY + +DI L+K+ +G Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 130 PFPSQFNFVPP--GRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFRDFDHNLQ 186 P QF PP + C V GWG P S TLQE ++ L+D + C+ R ++ ++ Sbjct: 121 CLP-QFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIR 179 Query: 187 ---LCVGNPRKTKSAFKGDSGGPLLCAGVAQ------GIVSYGR--SDAKPPAVFTRISH 235 +C G PR +GDSGGPL+C A+ GI S+G + AK P V+T Sbjct: 180 STNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWP 239 Query: 236 YRPWINQILQAN 247 Y WI + +N Sbjct: 240 YLNWIASKIGSN 251 >5LHN-A nrPDB Length = 247 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 75/243 (30%), Positives = 115/243 (47%), Gaps = 23/243 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNG--PSKFCGGFLIRRNFVLTAAHC-----AGRSITV 74 I+GG + ++P+ A + G PS CGG LI +V +AAHC + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTL--HHDIMLLKLK----EKASLTLAVGT 128 LG + K EV + H Y +L H+DI LLK++ + A + ++ T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 129 LPFPSQFNFVPPGRMCRVAGWGR---TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL 185 + P +F P G C + G+G+ + L P + + VKL + H+ + N Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 186 Q-LCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGR--SDAKPPAVFTRISHYRP 238 + LC +P + KGDSGGPL+C GIVS+GR ++ P V+TR+SH+ Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLD 240 Query: 239 WIN 241 WI Sbjct: 241 WIQ 243 >1X7A-C nrPDB Length = 235 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 76/235 (32%), Positives = 106/235 (45%), Gaps = 19/235 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGP-SKFCGGFLIRRNFVLTAAHCA--GRSITVTLGA 78 I+GG KP P+ L NG FCGG +I +V+TAAHC G ITV G Sbjct: 1 IVGGENAKPGQFPWQVLL-----NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGE 55 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTST--LHHDIMLLKLKEKASLTLAVGTLPFPSQ-- 134 +N E E T Q+ VI+ H YN + HDI LL+L E +L V + + Sbjct: 56 YNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPR 193 N V+GWGR + LQ +K+ L+D C F ++ C G Sbjct: 116 TNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHE 175 Query: 194 KTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQ 242 K + +GDSGGP + GI+S+G A ++T++S Y WI + Sbjct: 176 GGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKE 230 >1BQY-A nrPDB Length = 234 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 75/235 (31%), Positives = 108/235 (45%), Gaps = 17/235 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN- 80 + GG EC + + L SNG CGG LI +++V+TAAHC + + G H+ Sbjct: 1 VFGGDECNINEHRSLVVL--FNSNG--FLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSK 56 Query: 81 --ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 + E+E T E K F + + DIML+KL S + + L PS V Sbjct: 57 KILNEDEQTRDPKE--KFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSV 114 Query: 139 PPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFRDFDH--NLQLCVGNPRKT 195 G +CR+ GWG+T K D + ++D C + N LC G + Sbjct: 115 --GSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGG 172 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQAN 247 + DSGGPL+C G+ QGIVS+G P V+T++ Y WI I+ N Sbjct: 173 RDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >6I44-A nrPDB Length = 627 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 116/251 (46%), Gaps = 20/251 (7%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----- 67 +C+ + I+GGT+ P+ L++ + CGG LI +VLTAAHC Sbjct: 371 VCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLT-AQRHLCGGSLIGHQWVLTAAHCFDGLP 429 Query: 68 ---AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTL 124 R + L +IT++ Q E+I H Y S +HDI L+KL+ T Sbjct: 430 LQDVWRIYSGILQLSDITKDTPFSQIKEIII---HQNYKVSEGNHDIALIKLQAPLQYTE 486 Query: 125 AVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDH 183 + PS+ + C V GWG + + LQ+V + L+ + C ++D+ Sbjct: 487 FQKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKI 546 Query: 184 NLQL-CVGNPRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAK--PPAVFTRISHY 236 ++ C G K A KGD+GGPL+C GI S+G A+ P V+T+++ Y Sbjct: 547 TQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 606 Query: 237 RPWINQILQAN 247 WI + Q++ Sbjct: 607 MDWILEKTQSS 617 >5XW8-A nrPDB Length = 133 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 53/132 (40%), Positives = 68/132 (51%), Gaps = 7/132 (5%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 80 +I+GG C +S PY L N S FCGG LI +V++AAHC I V LG HN Sbjct: 8 KIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHN 62 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 I E Q + K HP +N +TL +DIML+KL A+L V T+ P Sbjct: 63 IDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS--CAAA 120 Query: 141 GRMCRVAGWGRT 152 G C ++GWG T Sbjct: 121 GTECLISGWGNT 132 >2F91-A nrPDB Length = 237 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 68/234 (29%), Positives = 102/234 (43%), Gaps = 17/234 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-------RSITV 74 I+GGT+ PY + FCG + N+ +TA HC + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 G +++ E + Q + V K H ++ + L +DI LLKL + V + P Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ--LCVGNP 192 G + V GWG T D LQ+V + L+ + C D L +C G P Sbjct: 121 -GHTATGDVI-VTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 193 RKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAKP--PAVFTRISHYRPWI 240 K + +GDSGGPL + GIVS+G A+P P V+T +S++ WI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWI 232 >1FIW-A nrPDB Length = 290 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 114/245 (46%), Gaps = 27/245 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKF--CGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 IIGG + + P+M L+I T + ++ CGG L+ ++LTAAHC VT Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 80 NITEEEDTW----------QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTL 129 +E W Q+ V K H KY+ S+ +DI L+K+ + +G Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 130 PFPSQFNFVPPG--RMCRVAGWG-RTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ 186 P QF PP + C VAGWG + S LQE ++ L+D C+ R ++ ++ Sbjct: 121 CLP-QFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIR 179 Query: 187 ---LCVGNPRKTKSAFKGDSGGPLLCAGVAQ------GIVSYGR--SDAKPPAVFTRISH 235 +C G P +GDSGGPL+C A+ GI S+G + AK P V+T Sbjct: 180 STNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWS 239 Query: 236 YRPWI 240 Y WI Sbjct: 240 YLNWI 244 >2OLG-A nrPDB Length = 278 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 79/270 (29%), Positives = 122/270 (45%), Gaps = 40/270 (14%) Query: 7 PLLLFLLCS-RAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKF-CGGFLIRRNFVLTA 64 P LL C + EA +I+ G + P P+ A + S+ +F CGG LI +++TA Sbjct: 7 PELLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTA 66 Query: 65 AHC-AGRSITVT-------LGAHNITEEEDTWQKLEVI-----------KQFRHPKY--N 103 AHC AGR + V LG N + D + + V + +HP Y Sbjct: 67 AHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDG 126 Query: 104 TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQ 163 + +HDI L++L + T + + P V G+ V GWGRT + S Q Sbjct: 127 SKDRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQY-STIKQ 185 Query: 164 EVKLRLMDPQACSHFRDFD------HNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQ--- 214 ++ + ++ + C+ + F + QLC G K K + GDSGGPLL Q Sbjct: 186 KLAVPVVHAEQCA--KTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFF 242 Query: 215 --GIVSYGRSDAKP--PAVFTRISHYRPWI 240 G+VS+G + P ++T++ YR WI Sbjct: 243 LEGLVSFGATCGTEGWPGIYTKVGKYRDWI 272 >4XDE-A nrPDB Length = 257 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 110/245 (44%), Gaps = 30/245 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTL 76 ++GG + PY+A L S FC G LI +VLTAAHC A +TV L Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-----FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA-----VGTLPF 131 G + Q L V H ++ + HD+ LL+L+E A + A V + Sbjct: 58 GQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSL 117 Query: 132 PSQFNFVPPGRMCRVAGWGR--TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---Q 186 PS +C+VAGWG G + S LQE ++ + + CS ++ Sbjct: 118 PSGAARPSETTLCQVAGWGHQFEGAEEYAS-FLQEAQVPFLSLERCSAPDVHGSSILPGM 176 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGVA-------QGIVSYGR--SDAKPPAVFTRISHYR 237 LC G A +GDSGGPL+C A QGI+S+G D P V+T +++Y Sbjct: 177 LCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYL 236 Query: 238 PWINQ 242 WI + Sbjct: 237 AWIRE 241 >1KIG-H nrPDB Length = 241 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/238 (29%), Positives = 112/238 (47%), Gaps = 17/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 I+GG +C P+ A L + G FCGG ++ +VLTAAHC + TV +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG---FCGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 N +EE EV +H ++ T DI +L+LK V P + ++ Sbjct: 58 NTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEK-DWAE 116 Query: 140 PGRMCR----VAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQL-CVGNPRK 194 M + V+G+GRT S TL+ +++ +D C F + C G + Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQ 176 Query: 195 TKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWINQILQA 246 + A +GDSGGP + GIVS+G A+ V+T++S++ WI++I++A Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKA 234 >2XXL-A nrPDB Length = 408 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 80/270 (29%), Positives = 110/270 (40%), Gaps = 41/270 (15%) Query: 14 CSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKF-CGGFLIRRNFVLTAAHCA---- 68 C + + G E K SRP+MA L G S+F CGG +I ++LTAAHC Sbjct: 111 CGNFLSQRVSNGYEVKLSSRPWMALLR-YQQFGESRFLCGGAMISERYILTAAHCVHGLQ 169 Query: 69 GRSITVTLGAHNITEEEDTWQK------------LEVIKQFRHPKYNTSTLHHDIMLLKL 116 + LG H I+ EED Q+ + + K H KY+ + HDI LLKL Sbjct: 170 NDLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKL 229 Query: 117 KEKASLTLAVGTLPFPSQFNFVPPGRMCR---VAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 + + P V GWG T SD L + + L Sbjct: 230 NRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTEN-GSSSDVLLQANVPLQPRS 288 Query: 174 ACSH-FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG---------------VAQGIV 217 ACS +R QLCVG + + KGDSGGPL V+QG+V Sbjct: 289 ACSQAYRRAVPLSQLCVGGG-DLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVV 347 Query: 218 SYGRSDAKPPAVFTRISHYRPWINQILQAN 247 + G+ P ++T + Y WI + +N Sbjct: 348 TCGQ--ISLPGLYTNVGEYVQWITDTMASN 375 >4LK4-A nrPDB Length = 357 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 70/210 (33%), Positives = 105/210 (50%), Gaps = 21/210 (10%) Query: 49 KFCGGFLIRRNFVLTAAHC----AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNT 104 +FCGG + +VLTAAHC + S+ V +GA+++ +++ K +RH Y+ Sbjct: 39 QFCGGSFLGGRYVLTAAHCFDSRSAASVDVIIGAYDLNNSSQG-ERIAAQKIYRHLSYSP 97 Query: 105 STLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDT--L 162 S L +DI +++L + +SL TL P+ +P VAGWG T KP T L Sbjct: 98 SNLLNDIAIVELAQTSSLPAI--TLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPIL 155 Query: 163 QEVKLRLMDPQAC----SHFRDFDHN-LQLCVGNPRKTKSAFKGDSGGPLLC-AGVAQ-G 215 QEV + L+ C H D N C R TK + +GD+GGP++ G Q G Sbjct: 156 QEVDVDLVSQSLCQIVMQHGISSDPNSTNFCAA--RLTKDSCQGDAGGPIVVKTGREQLG 213 Query: 216 IVSYGRSDAKPP---AVFTRISHYRPWINQ 242 IVS+G V+T +S++R WI + Sbjct: 214 IVSWGDEQCAKTGTYGVYTNVSYFRDWITK 243 >1BDA-A nrPDB Length = 265 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 77/252 (30%), Positives = 117/252 (46%), Gaps = 29/252 (11%) Query: 22 IIGGTECKPHSRPYMA--YLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITV 74 I GG S P+ A + + S G CGG LI ++L+AAHC +TV Sbjct: 14 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTV 73 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL----TLAVGTLP 130 LG + QK EV K H +++ T +DI LL+LK +S + V T+ Sbjct: 74 ILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVC 133 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACS--HF--RDFDHNL 185 P +P C ++G+G+ L P S+ L+E +RL C+ H R N+ Sbjct: 134 LPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNM 193 Query: 186 QLCVGNPR------KTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAKP--PAVFTRI 233 LC G+ R A +GDSGGPL+C + GI+S+G + P V+T++ Sbjct: 194 -LCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKV 252 Query: 234 SHYRPWINQILQ 245 ++Y WI ++ Sbjct: 253 TNYLDWIRDNMR 264 >4Z6A-H nrPDB Length = 249 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 74/246 (30%), Positives = 113/246 (45%), Gaps = 29/246 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GG C P+ L + NG ++ CGG LI +V++AAHC R++ L Sbjct: 1 IVGGKVCPKGECPWQVLLLV---NG-AQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ-- 134 G H+++E + Q V + Y T +HDI LL+L + LT V L P + Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 135 ----FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKL---RLMDPQACSHFRDFDHNLQL 187 FV R V+GWG+ +L G+ L+ + L RLM + + Sbjct: 117 SERTLAFV---RFSLVSGWGQ--LLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMF 171 Query: 188 CVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWIN 241 C G +K + KGDSGGP GIVS+G+ A V+TR+S Y W+ Sbjct: 172 CAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQ 231 Query: 242 QILQAN 247 +++++ Sbjct: 232 KLMRSE 237 >1C5M-D nrPDB Length = 255 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 67/238 (28%), Positives = 112/238 (47%), Gaps = 19/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 I+GG ECK P+ A L + G FCGG ++ ++LTAAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 N +EE EV +H ++ T DI +L+LK + + V P + ++ Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPER-DWAE 116 Query: 140 PGRMCR----VAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPR 193 M + V+G+GRT S L+ +++ +D +C F N+ C G Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM-FCAGYDT 175 Query: 194 KTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWINQILQ 245 K + A +GDSGGP + GIVS+G A+ ++T+++ + WI++ ++ Sbjct: 176 KQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >3P8G-A nrPDB Length = 241 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 108/240 (45%), Gaps = 22/240 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 ++GGT+ P+ L + G CG LI N++++AAHC Sbjct: 1 VVGGTDADEGEWPWQVSLHAL---GQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 72 ITVTLGAHNITEEEDTW-QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLP 130 T LG H+ ++ Q+ + + HP +N T +DI LL+L++ A + V + Sbjct: 58 WTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPIC 117 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ-LCV 189 P + P G+ V GWG T G+ LQ+ ++R++ C + + +CV Sbjct: 118 LPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCV 177 Query: 190 GNPRKTKSAFKGDSGGPLLCAGV-----AQGIVSYGRSDAK--PPAVFTRISHYRPWINQ 242 G + +GDSGGPL G+VS+G A+ P V+TR+ +R WI + Sbjct: 178 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 237 >2ASU-B nrPDB Length = 234 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 69/240 (28%), Positives = 111/240 (46%), Gaps = 30/240 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--------AGRSIT 73 ++GG P + P+ L + FCGG L++ ++LTA C G + Sbjct: 1 VVGG---HPGNSPWTVSLR---NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 74 VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 + N E + Q++ V K P + ++LLKL+ +L V + P Sbjct: 55 LGTLFQNPQHGEPSLQRVPVAKMVCGPSGS------QLVLLKLERSVTLNQRVALICLPP 108 Query: 134 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVK-LRLMDPQACS-HFRDFDHNLQLCVGN 191 ++ VPPG C +AGWG T G+DT+ V L ++ Q C+ R ++C Sbjct: 109 EWYVVPPGTKCEIAGWGETK--GTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEG 166 Query: 192 PRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQ 245 A +GD GGPL C + V +GI+ R A+ PAVFTR+S + WI+++++ Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >3VGC-B nrPDB Length = 131 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 50/132 (37%), Positives = 68/132 (51%), Gaps = 4/132 (3%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-GRSITVTLGAHN 80 I+ G E P S P+ L+ T FCGG LI N+V+TAAHC S V G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTG---FHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 57 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + QKL++ K F++ KYN+ T+++DI LLKL AS + V + PS + Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 117 Query: 141 GRMCRVAGWGRT 152 G C GWG T Sbjct: 118 GTTCVTTGWGLT 129 >2F83-A nrPDB Length = 625 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 109/247 (44%), Gaps = 16/247 (6%) Query: 14 CSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----A 68 C+ I+GGT P+ L TS CGG +I ++LTAAHC + Sbjct: 380 CTTKIKPRIVGGTASVRGEWPWQVTLH-TTSPTQRHLCGGSIIGNQWILTAAHCFYGVES 438 Query: 69 GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGT 128 + + V G N +E ++ V + H +Y + +DI LLKL+ + T + Sbjct: 439 PKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRP 498 Query: 129 LPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL--- 185 + PS+ + C V GWG + +TLQ+ K+ L+ + C R H + Sbjct: 499 ICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHK 557 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLCAGVA----QGIVSYGRSDAK--PPAVFTRISHYRPW 239 +C G K A KGDSGGPL C GI S+G A+ P V+T + Y W Sbjct: 558 MICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDW 617 Query: 240 INQILQA 246 I + QA Sbjct: 618 ILEKTQA 624 >1A5I-A nrPDB Length = 265 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 27/236 (11%) Query: 32 SRPYMA--YLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITVTLGAHNITEE 84 S P+ A + + S+G CGG LI +VLTAAHC S + V LG + Sbjct: 24 SHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKP 83 Query: 85 EDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEK----ASLTLAVGTLPFPSQFNFVPP 140 + Q +V K H +++ T ++DI LL+LK A + +V + P +P Sbjct: 84 GEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQLPD 143 Query: 141 GRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSH---FRDFDHNLQLCVGNPR--- 193 C ++G+G+ P S+ L+E +RL C+ F N LC G+ R Sbjct: 144 WTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGE 203 Query: 194 ---KTKSAFKGDSGGPLLCAGVAQ----GIVSYGR--SDAKPPAVFTRISHYRPWI 240 A +GDSGGPL+C GI+S+G + P V+T++++Y WI Sbjct: 204 IYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNYLGWI 259 >1P57-B nrPDB Length = 255 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 27/249 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITV----TLG 77 I+GG + P+ L ++ CGG L+ ++VLTAAHC V + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAH----LCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKY------NTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 A + + +L V H Y N+ +DI L+ L LT + + Sbjct: 57 AGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 116 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LC 188 P+ + G++C V GWG T + LQE ++ ++ C+ + + ++ C Sbjct: 117 PAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFC 176 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQ--------GIVSYGR--SDAKPPAVFTRISHYRP 238 G P A +GDSGGP +C GIVS+G + A+ P V+T++S +R Sbjct: 177 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE 236 Query: 239 WINQILQAN 247 WI Q ++ + Sbjct: 237 WIFQAIKTH 245 >3T2N-A nrPDB Length = 372 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 27/249 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITV----TLG 77 I+GG + P+ L ++ CGG L+ ++VLTAAHC V + Sbjct: 118 IVGGRDTSLGRWPWQVSLRYDGAH----LCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 173 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKY------NTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 A + + +L V H Y N+ +DI L+ L LT + + Sbjct: 174 AGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 233 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LC 188 P+ + G++C V GWG T + LQE ++ ++ C+ + + ++ C Sbjct: 234 PAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFC 293 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQ--------GIVSYGR--SDAKPPAVFTRISHYRP 238 G P A +GDSGGP +C GIVS+G + A+ P V+T++S +R Sbjct: 294 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE 353 Query: 239 WINQILQAN 247 WI Q ++ + Sbjct: 354 WIFQAIKTH 362 >2JET-B nrPDB Length = 128 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 46/129 (35%), Positives = 70/129 (54%), Gaps = 4/129 (3%) Query: 25 GTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGR-SITVTLGAHNITE 83 G + P S P+ L+ T FCGG LI ++V+TAAHC + S V G + Sbjct: 1 GEDAIPGSWPWQVSLQDKTG---FHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGS 57 Query: 84 EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRM 143 +E+ Q L++ + F++PK+N T+ +DI LLKL A + V + P+ + PPG + Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 144 CRVAGWGRT 152 C GWG+T Sbjct: 118 CATTGWGKT 126 >3DFJ-A nrPDB Length = 263 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/218 (31%), Positives = 97/218 (44%), Gaps = 30/218 (13%) Query: 50 FCGGFLIRRNFVLTAAHC-----AGRSITVTLGAHNI-TEEEDTWQKLEVIKQF-RHPKY 102 CGG L+ +VL+AAHC + V LGAH + + ED K+ +K HP Y Sbjct: 25 VCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDA--KVSTLKDIIPHPSY 82 Query: 103 NTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTG----VLKPG 158 DI LL+L + + + + P+ P G C V GWG +L P Sbjct: 83 LQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPNGLHCTVTGWGHVAPSVSLLTP- 141 Query: 159 SDTLQEVKLRLMDPQACSHFRDFD------HNLQ---LCVGNPRKTKSAFKGDSGGPLLC 209 LQ++++ L+ + C+ + D H +Q +C G K A +GDSGGPL C Sbjct: 142 -KPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC 200 Query: 210 A----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWIN 241 GIVS+G + P V+T S Y WI Sbjct: 201 PVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 238 >3E0N-B nrPDB Length = 271 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/218 (31%), Positives = 97/218 (44%), Gaps = 30/218 (13%) Query: 50 FCGGFLIRRNFVLTAAHC-----AGRSITVTLGAHNI-TEEEDTWQKLEVIKQF-RHPKY 102 CGG L+ +VL+AAHC + V LGAH + + ED K+ +K HP Y Sbjct: 25 VCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDA--KVSTLKDIIPHPSY 82 Query: 103 NTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTG----VLKPG 158 DI LL+L + + + + P+ P G C V GWG +L P Sbjct: 83 LQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPNGLHCTVTGWGHVAPSVSLLTP- 141 Query: 159 SDTLQEVKLRLMDPQACSHFRDFD------HNLQ---LCVGNPRKTKSAFKGDSGGPLLC 209 LQ++++ L+ + C+ + D H +Q +C G K A +GDSGGPL C Sbjct: 142 -KPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC 200 Query: 210 A----GVAQGIVSYGRS--DAKPPAVFTRISHYRPWIN 241 GIVS+G + P V+T S Y WI Sbjct: 201 PVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 238 >6AOD-C nrPDB Length = 245 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 106/239 (44%), Gaps = 16/239 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTL 76 I+GGT P+ L TS CGG +I ++LTAAHC + + + V Sbjct: 1 IVGGTASVRGEWPWQVTLH-TTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G +E ++ V + H +Y + +DI LLKL+ T + + PS+ + Sbjct: 60 GILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFR--DFDHNLQLCVGNPR 193 C V GWG + +TLQ+ K+ L+ + C +R H + +C G Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKM-ICAGYRE 178 Query: 194 KTKSAFKGDSGGPLLCAGVA----QGIVSYGRSDAK--PPAVFTRISHYRPWINQILQA 246 K A KGD+GGPL C GI S+G A+ P V+T + Y WI + QA Sbjct: 179 GGKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQA 237 >1SI5-H nrPDB Length = 240 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 99/210 (47%), Gaps = 22/210 (10%) Query: 50 FCGGFLIRRNFVLTAAHC----AGRSITVTLGAHNI--TEEEDTWQKLEVIKQFRHPKYN 103 CGG LI+ ++VLTA C + LG H++ +E Q L V + P+ + Sbjct: 24 ICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGS 83 Query: 104 TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQ 163 D++L+KL A L V T+ P+ + +P C V GWG TG++ L+ Sbjct: 84 ------DLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYTGLINY-DGLLR 136 Query: 164 EVKLRLMDPQACSHFRDFDHNL---QLCVGNPRKTKSAFKGDSGGPLLCAG----VAQGI 216 L +M + CS L ++C G + +GD GGPL+C + G+ Sbjct: 137 VAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGV 196 Query: 217 VSYGRSDAKP--PAVFTRISHYRPWINQIL 244 + GR A P P +F R+++Y WI++I+ Sbjct: 197 IVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >5KWM-A nrPDB Length = 230 Score = 83.6 bits (205), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 100/225 (44%), Gaps = 21/225 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS----ITVTLG 77 I+GG + P+ L VT +G +FCGG L N V+TAAHC S I V G Sbjct: 1 IVGGEDANVQDHPFTVAL--VTPDG-QQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLK---EKASLTLAVGTLPFPSQ 134 ++ E T K V + HP+Y + D+ +L L+ ++A + LA + Sbjct: 58 RTVMSSNEGTVSK--VTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAPIELA------KAD 109 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPR 193 P + GWG T +D LQ+ + + C + ++ + +C G P Sbjct: 110 DAGYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPE 169 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHY 236 +GDSGGP++ G+ S+G A+P P V+ R+ Y Sbjct: 170 GGVDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGKPGVYARVGAY 214 >4IGD-A nrPDB Length = 406 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/268 (26%), Positives = 116/268 (43%), Gaps = 36/268 (13%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 LP+ SR +I G + + P++A L + NG FCGG L+ ++++TAA Sbjct: 140 LPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHL--NG-QPFCGGSLLGSSWIVTAA 196 Query: 66 HCAGRSIT------------------VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTL 107 HC +S+ + LG H ++ Q L V HP+Y+ +T Sbjct: 197 HCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTF 256 Query: 108 HHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKL 167 +D+ L++L E L V + P G M V+GWG+ L+ +TL E+++ Sbjct: 257 ENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQ-FLQRFPETLMEIEI 313 Query: 168 RLMDPQACSH----FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQ------GIV 217 ++D C + +C G K A GDSGGP++ + G V Sbjct: 314 PIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTV 373 Query: 218 SYGRSDAKPP--AVFTRISHYRPWINQI 243 S+G K V++ I H + WI ++ Sbjct: 374 SWGDDCGKKDRYGVYSYIHHNKDWIQRV 401 >2PKA-B nrPDB Length = 152 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 52/149 (34%), Positives = 76/149 (51%), Gaps = 15/149 (10%) Query: 109 HDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDT------L 162 HD+MLL+L+ A +T AV L P+Q + G C +GWG ++PG D + Sbjct: 8 HDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGS---IEPGPDDFEFPDEI 62 Query: 163 QEVKLRLMDPQACSHFR-DFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR 221 Q V+L L+ C+ D LC G K GDSGGPL+C G+ QGI S+G Sbjct: 63 QCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGH 122 Query: 222 S---DAKPPAVFTRISHYRPWINQILQAN 247 + A P+++T++ Y WI+ + N Sbjct: 123 TPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1YM0-A nrPDB Length = 238 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 67/244 (27%), Positives = 115/244 (47%), Gaps = 24/244 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVTLG 77 I+GG E +P+ P+ + +S+ S FCGG +I +V+ AAHC A +++ +G Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSD--SHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN- 136 H+ + Q +V F + Y+ +TL +D+ ++K + + VG + P N Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 137 FVPPGRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACS--HFRDFDHNLQLCVGN 191 +V R + +GWG GV P L+ V L + C + D ++ +C + Sbjct: 119 YVY--RKSQCSGWGTINSGGVCCPA--VLRYVTLNITTNAFCDAVYTSDTIYDDMICATD 174 Query: 192 PR--KTKSAFKGDSGGPLLC---AGVAQ--GIVSYGRSDAKP-PAVFTRISHYRPWINQI 243 + + +GDSGGPL +G+ GIVS+G A P V++R+ + WI Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDT 234 Query: 244 LQAN 247 + N Sbjct: 235 ITNN 238 >2OQ5-A nrPDB Length = 232 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 66/238 (27%), Positives = 110/238 (46%), Gaps = 31/238 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---------AGRSI 72 I+GGTE + P+ A L+ S+ CG LI ++++AAHC S Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSH----RCGATLINATWLVSAAHCFTTYKNPARWTASF 56 Query: 73 TVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFP 132 VT+ + +++ V ++++HP ++ +DI L +L T AV + P Sbjct: 57 GVTIKPSKMKRGL---RRIIVHEKYKHPSHD-----YDISLAELSSPVPYTNAVHRVCLP 108 Query: 133 SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QLCV 189 PG + V G+G + L++ ++ L+D C+ + ++ + LC Sbjct: 109 DASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCA 168 Query: 190 GNPRKTKSAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKP--PAVFTRISHYRPWI 240 G+ A +GDSGGPL+ + GIVS+G AKP P V+TR++ R WI Sbjct: 169 GSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 226 >1EQ9-A nrPDB Length = 222 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 19/232 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GG + PY L + S CG ++ N VLTAAHC + V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G + ++E D + +V + Y+ L +D+ L+ L V + + Sbjct: 57 GTNYLSESGDVY---DVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDE 113 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRK 194 + C + GWG T + + LQE++L + + C +R D ++ ++ Sbjct: 114 DLES-NPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICTLT---KR 169 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYGRSDA-KPPAVFTRISHYRPWINQILQ 245 + A GDSGGPL+ G GIVS+G A P V+TR+S + WIN L+ Sbjct: 170 GEGACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLK 221 >4DJZ-B nrPDB Length = 251 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 67/252 (26%), Positives = 110/252 (43%), Gaps = 36/252 (14%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT-------- 73 I G + + P++A L + NG FCGG L+ ++++TAAHC +S+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHL--NG-QPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 74 ----------VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLT 123 + LG H ++ Q L V HP+Y+ +T +D+ L++L E L Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 117 Query: 124 LAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH----FR 179 V + P G M V+GWG+ L+ +TL E+++ ++D C + Sbjct: 118 AFVMPICLPEGPQ--QEGAMVIVSGWGKQ-FLQRFPETLMEIEIPIVDHSTCQKAYAPLK 174 Query: 180 DFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQ------GIVSYGRSDAKPP--AVFT 231 +C G K A GDSGGP++ + G VS+G K V++ Sbjct: 175 KKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYS 234 Query: 232 RISHYRPWINQI 243 I H + WI ++ Sbjct: 235 YIHHNKDWIQRV 246 >2B9L-A nrPDB Length = 394 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 64/244 (26%), Positives = 109/244 (44%), Gaps = 33/244 (13%) Query: 34 PYMAYL---EIVTSNGPSKF-CGGFLIRRNFVLTAAHCAGR------SITVTLGAHNITE 83 P+M + ++ +G + CGG LI + VLT AHC +I + G + Sbjct: 143 PWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLT 202 Query: 84 EEDT--WQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E++ +Q+ ++ + H +N T+ +D+ LL L +GT+ P Q Sbjct: 203 EKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQSQIFDST 262 Query: 142 RMCRVAGWGRT--GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQ-------LCVGN 191 C +GWG+ G S+ L++++L +D C + R+ L+ +C G Sbjct: 263 E-CFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGG 321 Query: 192 PRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRS--DAKPPAVFTRISHYRPWINQ 242 + K GD G PL C + GIV++G D P V+ ++H+R WI+Q Sbjct: 322 -EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVAHFRNWIDQ 380 Query: 243 ILQA 246 +QA Sbjct: 381 EMQA 384 >3F6U-H nrPDB Length = 240 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 60/209 (28%), Positives = 97/209 (46%), Gaps = 18/209 (8%) Query: 51 CGGFLIRRNFVLTAAHCAGRS--ITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLH 108 CG LI ++VLTAAHC S + V LG +++ E L++ + F HP Y+ ST Sbjct: 27 CGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTD 86 Query: 109 HDIMLLKLKEKASLTLAVGTLPFP----SQFNFVPPGRMCRVAGWGRTGVLKPGSD---- 160 +DI LL L + A+L+ + + P ++ G+ V GWG + + Sbjct: 87 NDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRT 146 Query: 161 -TLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQ 214 L +K+ ++ CS + LC G + A +GDSGGP++ + Sbjct: 147 FVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLV 206 Query: 215 GIVSYGRSDA--KPPAVFTRISHYRPWIN 241 G+VS+G V+T++S Y WI+ Sbjct: 207 GLVSWGEGCGLLHNYGVYTKVSRYLDWIH 235 >5O32-I nrPDB Length = 244 Score = 76.6 bits (187), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 107/242 (44%), Gaps = 33/242 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG + P+ ++ + CGG I ++LTAAHC S T + I Sbjct: 1 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKT---HRYQI 53 Query: 82 TEEEDTWQKLE--------VIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 W + V + H YN T +DI L+++K+ + P+ Sbjct: 54 WTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 113 Query: 134 QFNFVP----PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQ 186 + P P C V+GWGR +LQ +++L+ CS F R ++ ++ Sbjct: 114 CVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLI--SNCSKFYGNRFYEKEME 170 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGV-----AQGIVSYGRSDAKP--PAVFTRISHYRPW 239 C G + A KGDSGGPL+C G+VS+G + KP P V+T++++Y W Sbjct: 171 -CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 229 Query: 240 IN 241 I+ Sbjct: 230 IS 231 >2XRC-A nrPDB Length = 565 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 69/242 (28%), Positives = 108/242 (44%), Gaps = 33/242 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG + P+ ++ + CGG I ++LTAAHC S T + I Sbjct: 322 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKT---HRYQI 374 Query: 82 TEEEDTW----QKLEVIKQFR----HPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 W K VI+ H YN T +DI L+++K+ + P+ Sbjct: 375 WTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 434 Query: 134 QFNFVP----PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQ 186 + P P C V+GWGR +LQ +++L+ CS F R ++ ++ Sbjct: 435 CVPWSPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLI--SNCSKFYGNRFYEKEME 491 Query: 187 LCVGNPRKTKSAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKP--PAVFTRISHYRPW 239 C G + A KGDSGGPL+C G+VS+G + KP P V+T++++Y W Sbjct: 492 -CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 550 Query: 240 IN 241 I+ Sbjct: 551 IS 552 >1M9U-A nrPDB Length = 241 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 100/241 (41%), Gaps = 26/241 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTLG 77 +IGGT P P+ + S S CG L+ L+A+HC +I V G Sbjct: 1 VIGGTNASPGEFPWQLSQQ-RQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYN--TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 ++ T Q V H Y T++ +DI +L L SL + P+ Sbjct: 60 LWQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-------FRDFDHNLQLC 188 N G C ++GWGRT D LQ+ + ++ C+ +D+ +C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDN--HIC 176 Query: 189 VGNPRKTKSAFKGDSGGPLLC-------AGVAQGIVSYGRSDAKP--PAVFTRISHYRPW 239 V +P A GDSGGPL C GV +VS G P P+V+TR+S Y W Sbjct: 177 VQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGW 236 Query: 240 I 240 I Sbjct: 237 I 237 >6BQM-A nrPDB Length = 506 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 71/248 (28%), Positives = 112/248 (45%), Gaps = 31/248 (12%) Query: 19 AGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI----TV 74 + IIGG + PYM + + N FCGG + +VLTAAHC + V Sbjct: 8 SSRIIGGEQATAGEWPYM--VALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDV 65 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGA ++ + +T +++ V + + H Y T+++ +DI +L+L E+ L + S Sbjct: 66 LLGAFDMN-DVNTAERIHVRQIYVHNSYITASMGNDIAVLEL-ERDPLPRRSVQISDSSD 123 Query: 135 FNFVPPGRMCRVAGWG-RTGVLKPGSD-------------TLQEVKLRLMDPQACSHFRD 180 FN + V G+G R V SD L E K + D A +++ Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 181 FDHNLQLCVGNPRKTKSAFKGDSGGPLL---CAGVAQ-GIVSYGR--SDAKPPAVFTRIS 234 +N C G+ K A GD+GGP+ G Q G+VS+G A P V+T +S Sbjct: 184 LTNN-AFCAGS--FGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLS 240 Query: 235 HYRPWINQ 242 + W++ Sbjct: 241 VFNDWLDD 248 >3I77-A nrPDB Length = 230 Score = 73.6 bits (179), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 66/233 (28%), Positives = 98/233 (42%), Gaps = 24/233 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---AGRSITVTLGA 78 ++GGT P+M L + G FCGG L ++ VLTAAHC +G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG---FCGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P + T D L+KL + + TL + T +Q F Sbjct: 58 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 117 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPRKT 195 VAGWG L + + + AC F N +C G P Sbjct: 118 T-------VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 196 K-SAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKP--PAVFTRISHYRPWI 240 +GDSGGP+ A GIVS+G A+P P V+T +S + I Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAI 223 >2HLC-A nrPDB Length = 230 Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 103/232 (44%), Gaps = 19/232 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 II G E PY A L+I + +CGG LI ++LTAAHC S+ V LG+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKE-KASLTLAVGTLPFPSQFNFV 138 E E +I H +N T +D+ L+K+ + + + LP + N Sbjct: 61 VQYEGEAVVNSERIIS---HSMFNPDTYLNDVALIKIPHVEYTDNIQPIRLPSGEELNNK 117 Query: 139 PPGRMCRVAGWGRTGVLKPGSDT--LQEVKLRLMDPQACSHFRDFDHNLQLCV-GNPRKT 195 V+GWG++ +DT LQ ++D C+ ++ + G+ Sbjct: 118 FENIWATVSGWGQS-----NTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDG 172 Query: 196 KSAFKGDSGGPLLCA--GVAQGIVSY---GRSDAKPPAVFTRISHYRPWINQ 242 KS GDSGGP + + + G+VS+ ++ P F+R++ Y WI Q Sbjct: 173 KSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >2QY0-B nrPDB Length = 242 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 113/251 (45%), Gaps = 39/251 (15%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---------AGRSI 72 IIGG + K + P+ + I G G L+ ++LTAAH + S+ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRGG------GALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 73 TVTLGAHNITEEEDTWQKLEVIKQFRHPKY---NTSTLHHDIMLLKLKEKASLTLAVGTL 129 V LG N+ EE + + HP Y + DI LL+L+ S+TL L Sbjct: 55 DVFLGHTNV-EELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELEN--SVTLGPNLL 111 Query: 130 P--FPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF-------RD 180 P P F G M V+G+G + + + L+ V+L + +PQAC ++ Sbjct: 112 PICLPDNDTFYDLGLMGYVSGFGV--MEEKIAHDLRFVRLPVANPQACENWLRGKNRMDV 169 Query: 181 FDHNLQLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGRSDAKPPAVFTRIS 234 F N+ C G+P + A +GDSGG P VA GIVS+G ++ +T++ Sbjct: 170 FSQNM-FCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVL 228 Query: 235 HYRPWINQILQ 245 +Y WI + ++ Sbjct: 229 NYVDWIKKEME 239 >3NXP-A nrPDB Length = 424 Score = 70.1 bits (170), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 69/262 (26%), Positives = 111/262 (42%), Gaps = 41/262 (15%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 164 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 70 RSITVTLGAHNITEEEDTWQKLEVIKQ-FRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ ++++ + HP+YN L DI L+KLK+ + + + Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 281 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC--- 175 + P + + + G RV GWG V K LQ V L +++ C Sbjct: 282 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 341 Query: 176 SHFRDFDHNLQLCVG---NPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRS---D 223 + R D+ C G + K A +GDSGGP + GIVS+G D Sbjct: 342 TRIRITDN--MFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 399 Query: 224 AKPPAVFTRISHYRPWINQILQ 245 K +T + + WI +++ Sbjct: 400 GK-YGFYTHVFRLKKWIQKVID 420 >2OCV-B nrPDB Length = 259 Score = 70.1 bits (170), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 37/231 (16%) Query: 50 FCGGFLIRRNFVLTAAHC----------AGRSITVTLGAHNITEEEDTWQKLEVIKQ-FR 98 CG LI +VLTAAHC + V +G H+ T E +K+ ++++ + Sbjct: 27 LCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYV 86 Query: 99 HPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ---FNFVPPGRMCRVAGWGR--- 151 HP+YN L DI LLKLK+ + + + P + + + G RV GWG Sbjct: 87 HPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRE 146 Query: 152 ---TGVLKPGSDTLQEVKLRLMDPQAC---SHFRDFDHNLQLCVG---NPRKTKSAFKGD 202 T + + LQ V L +++ C + R D+ C G N K A +GD Sbjct: 147 TWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDN--MFCAGFKVNDTKRGDACEGD 204 Query: 203 SGGPLLCAG------VAQGIVSYGRS-DAKPP-AVFTRISHYRPWINQILQ 245 SGGP + GIVS+G D K +T + + WI +++ Sbjct: 205 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKAWIQKVID 255 >1GPZ-A nrPDB Length = 399 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 72/252 (28%), Positives = 115/252 (45%), Gaps = 39/252 (15%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---------AGRS 71 +IIGG + K + P+ + I G G L+ ++LTAAH + S Sbjct: 157 QIIGGQKAKMGNFPWQVFTNIHGRGG------GALLGDRWILTAAHTLYPKEHEAQSNAS 210 Query: 72 ITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHH---DIMLLKLKEKASLTLAVGT 128 + V LG N+ EE + + HP Y ++ DI LL+L+ S+TL Sbjct: 211 LDVFLGHTNV-EELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELEN--SVTLGPNL 267 Query: 129 LP--FPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF-------R 179 LP P F G M V+G+G + + + L+ V+L + +PQAC ++ Sbjct: 268 LPICLPDNDTFYDLGLMGYVSGFGV--MEEKIAHDLRFVRLPVANPQACENWLRGKNRMD 325 Query: 180 DFDHNLQLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGRSDAKPPAVFTRI 233 F N+ C G+P + A +GDSGG P VA GIVS+G ++ +T++ Sbjct: 326 VFSQNM-FCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKV 384 Query: 234 SHYRPWINQILQ 245 +Y WI + ++ Sbjct: 385 LNYVDWIKKEME 396 >1VR1-H nrPDB Length = 261 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 70/261 (26%), Positives = 113/261 (43%), Gaps = 39/261 (14%) Query: 22 IIGGTECKPHSRPY--MAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 I+ G++ + P+ M + + S G CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 70 RSITVTLGAHNITEEEDTWQKLEVIKQ-FRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ ++++ + HP+YN L DI L+KLK+ + + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC--- 175 + P + + + G RV GWG V K LQ V L +++ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 176 SHFRDFDHNLQLCVGNPRKTK--SAFKGDSGGPLLCAG------VAQGIVSYGRS---DA 224 + R D N+ P + K A +GDSGGP + GIVS+G D Sbjct: 181 TRIRITD-NMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 239 Query: 225 KPPAVFTRISHYRPWINQILQ 245 K +T + + WI +++ Sbjct: 240 K-YGFYTHVFRLKKWIQKVID 259 >3K65-B nrPDB Length = 308 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/262 (25%), Positives = 111/262 (42%), Gaps = 41/262 (15%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 48 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 70 RSITVTLGAHNITEEEDTWQKLEVIKQ-FRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ ++++ + HP+YN L DI L+KLK+ + + + Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 165 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC--- 175 + P + + + G RV GWG V K LQ V L +++ C Sbjct: 166 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 225 Query: 176 SHFRDFDHNLQLCVG---NPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRS---D 223 + R D+ C G + K A +GD+GGP + GIVS+G D Sbjct: 226 TRIRITDN--MFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 283 Query: 224 AKPPAVFTRISHYRPWINQILQ 245 K +T + + WI +++ Sbjct: 284 GK-YGFYTHVFRLKKWIQKVID 304 >3BEU-A nrPDB Length = 224 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 95/232 (40%), Gaps = 28/232 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---AGRSITVTLGA 78 ++GGT P+M L S CGG L ++ VLTAAHC +G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P + T D L+KL + + TL + T +Q F Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 112 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPRKT 195 VAGWG L + + + AC F N +C G K Sbjct: 113 T-------VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQ 165 Query: 196 KSAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKPP--AVFTRISHYRPWI 240 + +GDSGGP+ A GIVS+G A+ V+T +S + I Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAI 217 >4BXW-A nrPDB Length = 423 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 112/246 (45%), Gaps = 27/246 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 79 I+ G +CK P+ A L FCGG ++ +VLTAAHC +I+V +G Sbjct: 170 IVNGMDCKLGECPWQAAL---VDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEI 226 Query: 80 NITEEED----TWQKLEVIKQFRHP----KYNTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 + + E + K+ V K+F P K++ + +DI ++++K + V Sbjct: 227 DKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACL 286 Query: 132 PSQFNFVPPGRMCR----VAGWGRTGVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNL 185 P+ +F M + V+G+GR P S TL+ +K+ +D C S N+ Sbjct: 287 PTA-DFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNM 345 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPPAV--FTRISHYRPW 239 C G + A +GDSGGP GIVS G A+ +T++S + PW Sbjct: 346 -FCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPW 404 Query: 240 INQILQ 245 I +I++ Sbjct: 405 IKRIMR 410 >4NZQ-A nrPDB Length = 557 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 69/262 (26%), Positives = 111/262 (42%), Gaps = 41/262 (15%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 297 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 70 RSITVTLGAHNITEEEDTWQKLEVIKQ-FRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ ++++ + HP+YN L DI L+KLK+ + + + Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 414 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC--- 175 + P + + + G RV GWG V K LQ V L +++ C Sbjct: 415 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 474 Query: 176 SHFRDFDHNLQLCVG---NPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRS---D 223 + R D+ C G + K A +GDSGGP + GIVS+G D Sbjct: 475 TRIRITDN--MFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 532 Query: 224 AKPPAVFTRISHYRPWINQILQ 245 K +T + + WI +++ Sbjct: 533 GK-YGFYTHVFRLKKWIQKVID 553 >1MKW-K nrPDB Length = 308 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 107/262 (40%), Gaps = 41/262 (15%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G + + P+ L + CG LI +VLTAAHC Sbjct: 48 GRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 70 RSITVTLGAHNITEEEDTWQKLEVI-KQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ ++ K + HP+YN L DI LLKLK L+ + Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIH 165 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC--- 175 + P + + G RV GWG T V + LQ V L L++ C Sbjct: 166 PVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAS 225 Query: 176 SHFRDFDHNLQLCVG---NPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRS---D 223 + R D+ C G K A +GDSGGP + GIVS+G D Sbjct: 226 TRIRITDN--MFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRD 283 Query: 224 AKPPAVFTRISHYRPWINQILQ 245 K +T + + WI +++ Sbjct: 284 GK-YGFYTHVFRLKKWIQKVID 304 >4IW4-E nrPDB Length = 279 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 71/263 (26%), Positives = 113/263 (42%), Gaps = 45/263 (17%) Query: 22 IIGGTECKPHSRPYMAYLEIV-TSNGPSK--FCGGFLIRRNFVLTAAHC----------- 67 IIGG +P P+ A + + TS P+ F G L+ +++LTAAH Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 68 --AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125 + +TV LG H++ ++ + HP +N +HDI L++L+E L Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGA-VNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 126 VGTLPFPSQFNFVP-PGRMCRVAGWGRTG-------VLKPG----SDTLQEVKLRLMDPQ 173 V + P P P + VAGWG + ++ G SD LQ VKL ++ Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 174 ACS---HFRDFDHNL---QLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGR 221 C R ++++ C G K GDSGG + V QG+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 222 SDA----KPPAVFTRISHYRPWI 240 + + V+T++S+Y W+ Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWV 262 >1MD7-A nrPDB Length = 328 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 71/251 (28%), Positives = 114/251 (45%), Gaps = 39/251 (15%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---------AGRSI 72 IIGG + K + P+ + I G G L+ ++LTAAH + S+ Sbjct: 90 IIGGQKAKMGNFPWQVFTNIHGRGG------GALLGDRWILTAAHTLYPKEHEAQSNASL 143 Query: 73 TVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHH---DIMLLKLKEKASLTLAVGTL 129 V LG N+ EE + + HP Y ++ DI LL+L+ S+TL L Sbjct: 144 DVFLGHTNV-EELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELEN--SVTLGPNLL 200 Query: 130 P--FPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD------- 180 P P F G M V+G+G + + + L+ V+L + +PQAC ++ Sbjct: 201 PICLPDNDTFYDLGLMGYVSGFGV--MEEKIAHDLRFVRLPVANPQACENWLRGKNRMDV 258 Query: 181 FDHNLQLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGRSDAKPPAVFTRIS 234 F N+ C G+P + A +GD+GG P VA GIVS+G ++ +T++ Sbjct: 259 FSQNM-FCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVL 317 Query: 235 HYRPWINQILQ 245 +Y WI + ++ Sbjct: 318 NYVDWIKKEME 328 >1ETT-H nrPDB Length = 259 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 39/232 (16%) Query: 50 FCGGFLIRRNFVLTAAHC----------AGRSITVTLGAHNITEEEDTWQKLEVI-KQFR 98 CG LI +VLTAAHC + V +G H+ T E +K+ ++ K + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYI 86 Query: 99 HPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ---FNFVPPGRMCRVAGWGR--- 151 HP+YN L DI LLKLK L+ + + P + + G RV GWG Sbjct: 87 HPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRE 146 Query: 152 ---TGVLKPGSDTLQEVKLRLMDPQAC---SHFRDFDHNLQLCVG---NPRKTKSAFKGD 202 T V + LQ V L L++ C + R D+ C G K A +GD Sbjct: 147 TWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDN--MFCAGYKPGEGKRGDACEGD 204 Query: 203 SGGPLLCAG------VAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQ 245 SGGP + GIVS+G D K +T + + WI +++ Sbjct: 205 SGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGK-YGFYTHVFRLKKWIQKVID 255 >1PQ7-A nrPDB Length = 224 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/232 (28%), Positives = 102/232 (43%), Gaps = 23/232 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVTLG 77 I+GGT P++ + I + GP +CGG L+ N VLTAAHC A + G Sbjct: 1 IVGGTSASAGDFPFI--VSISRNGGP--WCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 + + T T L ++ HP Y S ++D+ +LKL +G + + Sbjct: 57 SLSRTSGGIT-SSLSSVRV--HPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDT---LQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNP 192 G VAGWG T + GS T L +V + ++ C + N C G Sbjct: 112 PVAGSSATVAGWGAT--SEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVS 169 Query: 193 RKTKSAFKGDSGGPLL-CAGVAQGIVSYGRSDAKP--PAVFTRISHYRPWIN 241 K + +GDSGGP++ + G VS+G A+P V+ + R +I+ Sbjct: 170 SGGKDSCQGDSGGPIVDSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >2KAI-A nrPDB Length = 80 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 35/84 (41%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG EC+ +S P+ ++ + S CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGRECEKNSHPW----QVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTS 105 E E+T Q V F HP +N S Sbjct: 57 FENENTAQFFGVTADFPHPGFNLS 80 >5TO3-B nrPDB Length = 409 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 39/232 (16%) Query: 50 FCGGFLIRRNFVLTAAHC----------AGRSITVTLGAHNITEEEDTWQKLEVIKQ-FR 98 CG LI +VLTAAHC + V +G H+ T E +K+ ++++ + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 86 Query: 99 HPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ---FNFVPPGRMCRVAGWGR--- 151 HP+YN L DI L+KLK+ + + + + P + + + G RV GWG Sbjct: 87 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 146 Query: 152 ---TGVLKPGSDTLQEVKLRLMDPQAC---SHFRDFDHNLQLCVG---NPRKTKSAFKGD 202 V K LQ V L +++ C + R D+ C G + K A +GD Sbjct: 147 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDN--MFCAGYKPDEGKRGDACEGD 204 Query: 203 SGGPLLCAG------VAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQ 245 SGGP + GIVS G D K +T + + WI +++ Sbjct: 205 SGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGK-YGFYTHVFRLKKWIQKVID 255 >4KKD-A nrPDB Length = 433 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 70/263 (26%), Positives = 112/263 (42%), Gaps = 45/263 (17%) Query: 22 IIGGTECKPHSRPYMAYLEIV-TSNGPSK--FCGGFLIRRNFVLTAAHC----------- 67 IIGG +P P+ A + + TS P+ F G L+ +++LTAAH Sbjct: 155 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 214 Query: 68 --AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125 + +TV LG H++ ++ + HP +N +HDI L++L+E L Sbjct: 215 PVSKEHVTVYLGLHDVRDKSGAVNS-SAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 126 VGTLPFPSQFNFVP-PGRMCRVAGWGRTG-------VLKPG----SDTLQEVKLRLMDPQ 173 V + P P P + VAGWG + ++ G SD LQ VKL ++ Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 174 ACS---HFRDFDHNL---QLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGR 221 C R ++++ C G K GDSG + V QG+VS+G Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWGG 393 Query: 222 SDA----KPPAVFTRISHYRPWI 240 + + V+T++S+Y W+ Sbjct: 394 PEECGSKQVYGVYTKVSNYVDWV 416 >2FMJ-A nrPDB Length = 222 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/232 (26%), Positives = 97/232 (41%), Gaps = 30/232 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---AGRSITVTLGA 78 ++GGT P+M L S CGG L ++ VLTAAHC +G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P YN + D L+KL + + TL + T +Q F Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLAQPINQPTLKIATTTAYNQGTF 110 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRKT 195 VAGWG L + + + AC ++ + N ++C G Sbjct: 111 T-------VAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 196 KSAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKPP--AVFTRISHYRPWI 240 +GDSGGP+ A GIVS+G A+ V+T +S + I Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAI 215 >1ZJK-A nrPDB Length = 403 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 71/269 (26%), Positives = 112/269 (41%), Gaps = 38/269 (14%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLT 63 LP+ + L +R G+I GG + KP P+ + T+ G L+ N+VLT Sbjct: 144 LPVCEPVCGLSARTTGGQIYGGQKAKPGDFPWQVLILGGTT------AAGALLYDNWVLT 197 Query: 64 AAHCA------GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKL 116 AAH ++ + +G T E + F H Y + + +DI L+KL Sbjct: 198 AAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAV--FIHEGYTHDAGFDNDIALIKL 255 Query: 117 KEKASLTLAVG--TLPFPSQFNFVPPGRMCRVAGWGRT--GVLKPGSDTLQEVKLRLMDP 172 K + + LP +F+ + +GWG T G L + L V + ++D Sbjct: 256 NNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFL---ARNLMYVDIPIVDH 312 Query: 173 QACS-------HFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSY 219 Q C+ + R LC G K + +GDSGG L+ GIVS+ Sbjct: 313 QKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSW 372 Query: 220 GR---SDAKPPAVFTRISHYRPWINQILQ 245 G +A V+T++ +Y PWI I+ Sbjct: 373 GSMNCGEAGQYGVYTKVINYIPWIENIIS 401 >1Q3X-A nrPDB Length = 328 Score = 63.5 bits (153), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 71/269 (26%), Positives = 111/269 (41%), Gaps = 38/269 (14%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLT 63 LP+ + L +R G I GG + KP P+ + T+ G L+ N+VLT Sbjct: 69 LPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTT------AAGALLYDNWVLT 122 Query: 64 AAHCA------GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKL 116 AAH ++ + +G T E + F H Y + + +DI L+KL Sbjct: 123 AAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAV--FIHEGYTHDAGFDNDIALIKL 180 Query: 117 KEKASLTLAVG--TLPFPSQFNFVPPGRMCRVAGWGRT--GVLKPGSDTLQEVKLRLMDP 172 K + + LP +F+ + +GWG T G L + L V + ++D Sbjct: 181 NNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFL---ARNLMYVDIPIVDH 237 Query: 173 QACS-------HFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSY 219 Q C+ + R LC G K + +GDSGG L+ GIVS+ Sbjct: 238 QKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSW 297 Query: 220 GR---SDAKPPAVFTRISHYRPWINQILQ 245 G +A V+T++ +Y PWI I+ Sbjct: 298 GSMNCGEAGQYGVYTKVINYIPWIENIIS 326 >1ELV-A nrPDB Length = 333 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 41/260 (15%) Query: 18 EAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVT 75 E IIGG++ + P+ + + + + GG LI +VLTAAH R T+ Sbjct: 79 EKQRIIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREPTMY 131 Query: 76 LGAHNITEEEDTWQKLEVIKQ-FRHPKYN-------TSTLHHDIMLLKLKEKASLTLAVG 127 +G+ ++ K+ + F HP + + +DI L++LK+ + V Sbjct: 132 VGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVS 191 Query: 128 TLPFP---SQFNFVPPGRMCRVAGWGRT----------GVLKPGSDTLQEVKLRLMDPQA 174 + P S +N + G + ++GWGRT P + + ++++ P A Sbjct: 192 PICLPGTSSDYNLM-DGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTA 250 Query: 175 CSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDAKPP 227 + F N+ +C G + S KGDSGG A G+VS+G Sbjct: 251 DAEAYVFTPNM-ICAGGEKGMDSC-KGDSGGAFAVQDPNDKTKFYAAGLVSWG-PQCGTY 307 Query: 228 AVFTRISHYRPWINQILQAN 247 ++TR+ +Y WI + +Q N Sbjct: 308 GLYTRVKNYVDWIMKTMQEN 327 >5UBM-A nrPDB Length = 252 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 110/256 (42%), Gaps = 41/256 (16%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 IIGG++ + P+ + + + + GG LI +VLTAAH R T+ +G+ Sbjct: 2 IIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREPTMYVGST 54 Query: 80 NITEEEDTWQKLEVIKQ-FRHPKYN-------TSTLHHDIMLLKLKEKASLTLAVGTLPF 131 ++ K+ + F HP + + +DI L++LK+ + V + Sbjct: 55 SVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICL 114 Query: 132 P---SQFNFVPPGRMCRVAGWGRT----------GVLKPGSDTLQEVKLRLMDPQACSHF 178 P S +N + G + ++GWGRT P + + ++++ P A + Sbjct: 115 PGTSSDYNLM-DGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEA 173 Query: 179 RDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDAKPPAVFT 231 F N+ +C G + S KGDSGG A G+VS+G ++T Sbjct: 174 YVFTPNM-ICAGGEKGMDSC-KGDSGGAFAVQDPNDKTKFYAAGLVSWG-PQCGTYGLYT 230 Query: 232 RISHYRPWINQILQAN 247 R+ +Y WI + +Q N Sbjct: 231 RVKNYVDWIMKTMQEN 246 >4J1Y-A nrPDB Length = 397 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 63/260 (24%), Positives = 110/260 (42%), Gaps = 41/260 (15%) Query: 18 EAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVT 75 E IGG++ + P+ + + + + GG LI +VLTAAH R T+ Sbjct: 143 EKARAIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREPTMY 195 Query: 76 LGAHNITEEEDTWQKLEVIKQ-FRHPKYN-------TSTLHHDIMLLKLKEKASLTLAVG 127 +G+ ++ K+ + F HP + + +DI L++LK+ + V Sbjct: 196 VGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVS 255 Query: 128 TLPFP---SQFNFVPPGRMCRVAGWGRT----------GVLKPGSDTLQEVKLRLMDPQA 174 + P S +N + G + ++GWGRT P + + ++++ P A Sbjct: 256 PICLPGTSSDYNLM-DGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTA 314 Query: 175 CSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDAKPP 227 + F N+ +C G + S KGDSGG A G+VS+G Sbjct: 315 DAEAYVFTPNM-ICAGGEKGMDSC-KGDSGGAFAVQDPNDKTKFYAAGLVSWG-PQCGTY 371 Query: 228 AVFTRISHYRPWINQILQAN 247 ++TR+ +Y WI + +Q N Sbjct: 372 GLYTRVKNYVDWIMKTMQEN 391 >3H7T-A nrPDB Length = 235 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 57/240 (23%), Positives = 103/240 (42%), Gaps = 25/240 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG + P+ + ++ P FCGG ++ NFV+TAA C + + H Sbjct: 1 IIGGKKSDITKEPWA--VGVLVDEKP--FCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDI------MLLKLKEKASLTLAVGTLPFPSQF 135 + T + K+ +Y+ T+ ++ M +KL +K + + + +L + + Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPE- 115 Query: 136 NFVPPGRMCRVAGWGRTGV--LKPGSDTLQEVKLRLMDPQAC-SHFRDFD-----HNLQL 187 P V+GWG T L+ D L E ++D ++C ++ + ++ Sbjct: 116 ----PDTSVLVSGWGSTNFKSLEYSGD-LMEANFTVVDRKSCEEQYKQIEADKYIYDGVF 170 Query: 188 CVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRS-DAKPPAVFTRISHYRPWINQILQA 246 C G GD+G P + G G+ SY S ++ P+VF R+ +Y I I+ Sbjct: 171 CAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDIISG 230 >1AKS-B nrPDB Length = 98 Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 5/90 (5%) Query: 162 LQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVS- 218 LQ +K ++ +C S+ N+ +CVG + K + +GDSGGP++C G QGIVS Sbjct: 10 LQCLKAPVLSNSSCKSSYPGQITGNM-ICVGFLQGGKDSCQGDSGGPVVCNGQLQGIVSW 68 Query: 219 -YGRSDAKPPAVFTRISHYRPWINQILQAN 247 YG + P V+T++ +Y WI Q + AN Sbjct: 69 GYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1EPT-B nrPDB Length = 82 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 72 ITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 I V LG HNI E Q + K HP +N +TL +DIML+KL A+L V T+ Sbjct: 3 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 62 Query: 132 PSQFNFVPPGRMCRVAGWGRT 152 P + G C ++GWG T Sbjct: 63 PR--SCAAAGTECLISGWGNT 81 >3H7O-A nrPDB Length = 228 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/201 (25%), Positives = 85/201 (42%), Gaps = 8/201 (3%) Query: 51 CGGFLIRRNFVLTAAHCA--GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLH 108 CGG ++ + FVLTAAHC + T+ + + ED + + Y T+ Sbjct: 28 CGGAILSQWFVLTAAHCVFDQKPETIVIQYESTNLWEDPGKSDPYVSHVYLSFYRQETME 87 Query: 109 HDIMLLKLKEKASLT-LAVGTLPFPSQFNFVPP-GRMCRVAGWGRTGVLKPGSDTLQEVK 166 +DI +L+L L L P F P G V+G+G + P L+ + Sbjct: 88 NDIAILELSRPLKLDGLKSKPAKLPD-IEFRPKTGSDVLVSGYGDGQTMDPKDHDLKSAQ 146 Query: 167 LRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSY-GRSDA 224 L ++D C + + +LQ+ + S GD+G P + G+ +Y + Sbjct: 147 LTVVDLDECRTKYGPIFLSLQVFCAQ-KVGVSLESGDAGDPTVQQDTLVGVAAYFPKRPE 205 Query: 225 KPPAVFTRISHYRPWINQILQ 245 P VFT++ Y WI I++ Sbjct: 206 GAPEVFTKVGSYVSWIQDIIK 226 >4FXG-H nrPDB Length = 242 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 105/251 (41%), Gaps = 38/251 (15%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA------GRSITVT 75 I GG + KP P+ +++ G + G L+ N+VLTAAH ++ + Sbjct: 1 IYGGQKAKPGDFPW----QVLILGGTT--AAGALLYDNWVLTAAHAVYEQKHDASALDIR 54 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKLKEKASLTLAVG--TLPFP 132 +G T E + F H Y + + +DI L+KL K + + LP Sbjct: 55 MGTLKRLSPHYTQAWSEAV--FIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRK 112 Query: 133 SQFNFVPPGRMCRVAGWGRT--GVLKPGSDTLQEVKLRLMDPQACS-------HFRDFDH 183 +F+ + +GWG T G L + L V + ++D Q C+ + R Sbjct: 113 EAESFMRTDDIGTASGWGLTQRGFL---ARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVT 169 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGR---SDAKPPAVFTRIS 234 LC G K + +GD+GG L+ GIVS+G +A V+T++ Sbjct: 170 ANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVI 229 Query: 235 HYRPWINQILQ 245 +Y PWI I+ Sbjct: 230 NYIPWIENIIS 240 >1RIW-B nrPDB Length = 147 Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 17/144 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 72 ITVTLGAHNITEEEDTWQKLEVIKQ-FRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 + V +G H+ T E +K+ ++++ + HP+YN L DI L+KLK+ + + + + Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWG 150 P + + + G RV GWG Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWG 142 >4X0L-C nrPDB Length = 259 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 35/186 (18%) Query: 89 QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAG 148 Q +E+ K HP Y+ DI L+KLK+K S+ V + PS+ ++ GR+ V+G Sbjct: 82 QLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSK-DYAEVGRVGYVSG 136 Query: 149 WGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD--------------------HNLQLC 188 WGR K +D L+ V L + D C R ++ + C Sbjct: 137 WGRNANFK-FTDHLKYVMLPVADQDQC--IRHYEGSTVPEKKTPKSPVGVQPILNEHTFC 193 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGV------AQGIVSYGRSDAKPP-AVFTRISHYRPWIN 241 G + + GD+G + A GI+S+ +S A V+ +++ + W+ Sbjct: 194 AGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQ 253 Query: 242 QILQAN 247 + + N Sbjct: 254 KTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 35/186 (18%) Query: 89 QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAG 148 Q +E+ K HP Y+ DI L+KLK+K S+ V + PS+ ++ GR+ V+G Sbjct: 138 QLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSK-DYAEVGRVGYVSG 192 Query: 149 WGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD--------------------HNLQLC 188 WGR K +D L+ V L + D C R ++ + C Sbjct: 193 WGRNANFK-FTDHLKYVMLPVADQDQC--IRHYEGSTVPEKKTPKSPVGVQPILNEHTFC 249 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGV------AQGIVSYGRSDAKPP-AVFTRISHYRPWIN 241 G + + GD+G + A GI+S+ +S A V+ +++ + W+ Sbjct: 250 AGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQ 309 Query: 242 QILQAN 247 + + N Sbjct: 310 KTIAEN 315 >1BBR-H nrPDB Length = 150 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 15/116 (12%) Query: 50 FCGGFLIRRNFVLTAAHC----------AGRSITVTLGAHNITEEEDTWQKLEVI-KQFR 98 CG LI +VLTAAHC + V +G H+ T E +K+ ++ K + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYI 86 Query: 99 HPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ---FNFVPPGRMCRVAGWG 150 HP+YN L DI LLKLK L+ + + P + + G RV GWG Sbjct: 87 HPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWG 142 >3RU4-E nrPDB Length = 96 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Query: 160 DTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQ 214 D LQ+ L L+ C + + +C G S+ GDSGGPL+C A Sbjct: 4 DRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWTLV 61 Query: 215 GIVSYGRS--DAKPPAVFTRISHYRPWINQILQAN 247 GIVS+G S P V+ R++ W+ Q L AN Sbjct: 62 GIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 96 >4F4O-C nrPDB Length = 347 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 51/261 (19%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG+ S P+ A + I N S G LI ++LT A + LG N Sbjct: 103 IMGGSLDAKGSFPWQAKM-ISHHNLTS---GATLINEQWLLTTAK------NLRLGHKND 152 Query: 82 TEEEDTW----------QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 T+ +D Q++E+ K HP +T DI L+KLK+K + V + Sbjct: 153 TKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV----DIGLIKLKQKVPVNERVMPICL 208 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD--------- 182 PS+ ++V G + V+GWGR L ++ L+ V L + D + C + + Sbjct: 209 PSK-DYVNVGLVGYVSGWGRNANLN-FTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPK 266 Query: 183 ---------HNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIVSYGRS-DAKP 226 + C G + + GD+G A GI+S+ +S Sbjct: 267 SPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAE 326 Query: 227 PAVFTRISHYRPWINQILQAN 247 V+ R++ WI + N Sbjct: 327 YGVYVRVTSILDWIQTTIADN 347 >2WIN-I nrPDB Length = 507 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 56/246 (22%), Positives = 94/246 (38%), Gaps = 64/246 (26%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTLGAHNITEEE 85 H +P+ A + ++ + + C G ++ FVLTAAHC SI V++G Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEK----- 286 Query: 86 DTWQKLEVIKQFRHPKYNTST---------LHHDIMLLKLKEKASLTLAVGTLPFP---- 132 + LE+ HP YN + +D+ L+KLK K + + P Sbjct: 287 ---RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 343 Query: 133 -SQFNFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQAC--- 175 ++ +PP C+ + L P D T +EV ++ D + Sbjct: 344 TTRALRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 399 Query: 176 --------SHFRDFDHNLQ---LCVG--NPRKTKSAFKGDSGGPLLCAG----VAQGIVS 218 +D + LC G +P + +GDSGGPL+ + G++S Sbjct: 400 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 459 Query: 219 YGRSDA 224 +G D Sbjct: 460 WGVVDV 465 >1DLE-A nrPDB Length = 298 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 57/246 (23%), Positives = 96/246 (39%), Gaps = 64/246 (26%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTLGAHNITEEE 85 H +P+ A + ++ + + C G ++ FVLTAAHC SI V++G Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEK----- 79 Query: 86 DTWQKLEVIKQFRHPKYNTST---------LHHDIMLLKLKEKASLTLAVGTLPFP---- 132 + LE+ HP YN + +D+ L+KLK K + + P Sbjct: 80 ---RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 136 Query: 133 -SQFNFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQ-ACSH 177 ++ +PP C+ + L P D T +EV ++ D + +C Sbjct: 137 TTRALRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 192 Query: 178 ----------FRDFDHNLQ---LCVG--NPRKTKSAFKGDSGGPLLCAG----VAQGIVS 218 +D + LC G +P + +GDSGGPL+ + G++S Sbjct: 193 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 252 Query: 219 YGRSDA 224 +G D Sbjct: 253 WGVVDV 258 >2JET-C nrPDB Length = 99 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 6/53 (11%) Query: 201 GDSGGPLLCA--GVAQ--GIVSYGRS--DAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C GV GIVS+G P V++R++ PW+ QIL+AN Sbjct: 47 GDSGGPLVCQKDGVWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILEAN 99 >2OK5-A nrPDB Length = 752 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 56/245 (22%), Positives = 94/245 (38%), Gaps = 64/245 (26%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTLGAHNITEEE 85 H +P+ A + ++ + + C G ++ FVLTAAHC SI V++G Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEK----- 530 Query: 86 DTWQKLEVIKQFRHPKYNTST---------LHHDIMLLKLKEKASLTLAVGTLPFP---- 132 + LE+ HP YN + +D+ L+KLK K + + P Sbjct: 531 ---RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 587 Query: 133 -SQFNFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQAC--- 175 ++ +PP C+ + L P D T +EV ++ D + Sbjct: 588 TTRALRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 643 Query: 176 --------SHFRDFDHNLQ---LCVG--NPRKTKSAFKGDSGGPLLCAG----VAQGIVS 218 +D + LC G +P + +GDSGGPL+ + G++S Sbjct: 644 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 703 Query: 219 YGRSD 223 +G D Sbjct: 704 WGVVD 708 >3H5C-B nrPDB Length = 317 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%) Query: 42 VTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAHNITEEEDTWQKLEVIKQFRH 99 +T++ FCGG +IR NFVLT A C+ R+ITV + +++ +++ H Sbjct: 111 LTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP---LMIKITHVHVH 167 Query: 100 PKYNTSTLHHDIMLLKLK-----EKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGV 154 +Y+ +D+ LL+L+ A L + F +P R ++GW R G Sbjct: 168 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHL-LIPRTRG-LLSGWARNGT 225 Query: 155 LKPGSDTLQEVKL 167 S T + V L Sbjct: 226 DLGNSLTTRPVTL 238 >3F1S-B nrPDB Length = 283 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%) Query: 42 VTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAHNITEEEDTWQKLEVIKQFRH 99 +T++ FCGG +IR NFVLT A C+ R+ITV + +++ +++ H Sbjct: 70 LTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP---LMIKITHVHVH 126 Query: 100 PKYNTSTLHHDIMLLKLK-----EKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGV 154 +Y+ +D+ LL+L+ A L + F +P R ++GW R G Sbjct: 127 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHL-LIPRTRG-LLSGWARNGT 184 Query: 155 LKPGSDTLQEVKL 167 S T + V L Sbjct: 185 DLGNSLTTRPVTL 197 >2I6S-A nrPDB Length = 517 Score = 33.5 bits (75), Expect = 0.097, Method: Compositional matrix adjust. Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 15/110 (13%) Query: 51 CGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQF-------RHPKYN 103 C G LI +VLTAAHC +L N+ + + W K +I++ K N Sbjct: 257 CRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKN 316 Query: 104 TSTLH---HDIMLLKLKEKASLTLAVG--TLPFPSQFNFV---PPGRMCR 145 L DI LLKL +K ++ LP + N P G CR Sbjct: 317 QGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCR 366 >2PFE-A nrPDB Length = 186 Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 5/53 (9%) Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 R T A GDSGGP L AQG+ S G D + I+ ++P IN +L Sbjct: 130 RTTACAEGGDSGGPWLTGSQAQGVTSGGTGDCRSGG----ITFFQP-INPLLS 177 >2EA3-A nrPDB Length = 189 Score = 31.6 bits (70), Expect = 0.35, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQA 246 R T A GDSGG LL AQG+ S G + + + ++P +N ILQA Sbjct: 127 RTTVCAEPGDSGGSLLAGNQAQGVTSGGSGNCRTGGT----TFFQP-VNPILQA 175 >1VDW-A nrPDB Length = 254 Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Query: 174 ACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPL-LCAGVAQGIV 217 A RDFDHN+ GNP+ +++ SG + VA+ I+ Sbjct: 10 AIDIIRDFDHNIMPLFGNPKASETISISPSGDETKVVDKVAENII 54 >3SVL-A nrPDB Length = 193 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFL 55 +IGG C+ H R + +L+ + N P +F GG + Sbjct: 120 VIGGARCQYHLRQILVFLDAMVMNKP-EFMGGVI 152 >2HNT-C nrPDB Length = 70 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC 67 I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHC 44 >1BBR-E nrPDB Length = 109 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 18/100 (18%) Query: 161 TLQEVKLRLMDPQAC---SHFRDFDHNLQLCVG---NPRKTKSAFKGDSGGPLLCAG--- 211 LQ V L L++ C + R D+ C G K A +GDSGGP + Sbjct: 9 VLQVVNLPLVERPVCKASTRIRITDN--MFCAGYKPGEGKRGDACEGDSGGPFVMKSPYN 66 Query: 212 ---VAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQ 245 GIVS+G D K +T + + WI +++ Sbjct: 67 NRWYQMGIVSWGEGCDRDGK-YGFYTHVFRLKKWIQKVID 105 >6EPE-S nrPDB Length = 530 Score = 27.3 bits (59), Expect = 6.1, Method: Compositional matrix adjust. Identities = 10/21 (47%), Positives = 15/21 (71%) Query: 90 KLEVIKQFRHPKYNTSTLHHD 110 KL+V++ F H + T+TL HD Sbjct: 219 KLDVVRSFLHARLRTATLRHD 239 >2HNT-F nrPDB Length = 105 Score = 26.9 bits (58), Expect = 7.2, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 20/89 (22%) Query: 166 KLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSY 219 ++R+ D C+ ++ + K A +GDSGGP + GIVS+ Sbjct: 24 RIRITDNMFCAGYKP----------DEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW 73 Query: 220 GRS---DAKPPAVFTRISHYRPWINQILQ 245 G D K +T + + WI +++ Sbjct: 74 GEGCDRDGK-YGFYTHVFRLKKWIQKVID 101 >4NWK-A nrPDB Length = 219 Score = 26.9 bits (58), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/21 (71%), Positives = 15/21 (71%), Gaps = 1/21 (4%) Query: 197 SAFKGDSGGPLLC-AGVAQGI 216 S KG SGGPLLC AG A GI Sbjct: 148 SYLKGSSGGPLLCPAGHAVGI 168 >6C2N-A nrPDB Length = 203 Score = 26.9 bits (58), Expect = 9.0, Method: Compositional matrix adjust. Identities = 15/21 (71%), Positives = 15/21 (71%), Gaps = 1/21 (4%) Query: 197 SAFKGDSGGPLLC-AGVAQGI 216 S KG SGGPLLC AG A GI Sbjct: 154 SYLKGSSGGPLLCPAGHAVGI 174 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1NN6-A nrPDB 342 8e-95 1UTJ-A nrPDB 313 5e-86 1EUF-A nrPDB 310 4e-85 1FI8-A nrPDB 307 2e-84 1F7Z-A nrPDB 307 3e-84 5C67-A nrPDB 304 2e-83 4AN7-A nrPDB 304 2e-83 5FXL-A nrPDB 301 2e-82 1A0J-A nrPDB 301 2e-82 4WWY-A nrPDB 300 3e-82 1IAU-A nrPDB 294 2e-80 2RDL-A nrPDB 292 8e-80 3RP2-A nrPDB 291 2e-79 3G01-A nrPDB 288 2e-78 4NFE-A nrPDB 284 2e-77 2TLD-E nrPDB 284 2e-77 1SGF-G nrPDB 282 9e-77 2EEK-A nrPDB 281 2e-76 3TK9-A nrPDB 281 2e-76 5TJX-A nrPDB 280 3e-76 1FXY-A nrPDB 280 3e-76 6I44-A nrPDB 280 3e-76 2F83-A nrPDB 278 1e-75 1BRU-P nrPDB 274 3e-74 1SPJ-A nrPDB 274 3e-74 5GVT-A nrPDB 273 5e-74 1KYN-A nrPDB 272 8e-74 3QUM-P nrPDB 268 2e-72 1PYT-D nrPDB 268 2e-72 4H4F-A nrPDB 267 3e-72 5MS3-A nrPDB 267 3e-72 5UGG-A nrPDB 267 4e-72 1X7A-C nrPDB 266 7e-72 4DUR-A nrPDB 266 8e-72 3LC3-A nrPDB 264 2e-71 2V35-A nrPDB 263 4e-71 1AO5-A nrPDB 263 4e-71 1NPM-A nrPDB 263 5e-71 3T2N-A nrPDB 263 6e-71 6QHB-A nrPDB 262 1e-70 3W94-A nrPDB 261 2e-70 2CGA-A nrPDB 261 2e-70 6AOD-C nrPDB 261 2e-70 3BSQ-A nrPDB 261 2e-70 1TON-A nrPDB 260 5e-70 1KIG-H nrPDB 259 9e-70 2F91-A nrPDB 258 1e-69 1ORF-A nrPDB 257 3e-69 1FDP-A nrPDB 257 4e-69 4MPW-A nrPDB 257 4e-69 4GSO-A nrPDB 255 9e-69 3K65-B nrPDB 255 1e-68 2AIQ-A nrPDB 255 1e-68 1MKW-K nrPDB 255 1e-68 4DGJ-A nrPDB 255 1e-68 1P57-B nrPDB 255 2e-68 2PSX-A nrPDB 254 2e-68 3NXP-A nrPDB 254 2e-68 1SGF-A nrPDB 254 2e-68 1C5M-D nrPDB 254 2e-68 1ELT-A nrPDB 253 3e-68 5ZFH-A nrPDB 253 4e-68 3E0N-B nrPDB 253 5e-68 3P8G-A nrPDB 253 5e-68 4NZQ-A nrPDB 253 7e-68 3DFJ-A nrPDB 253 7e-68 1GVZ-A nrPDB 252 8e-68 1LTO-A nrPDB 252 1e-67 3S9B-A nrPDB 252 1e-67 1FUJ-A nrPDB 251 2e-67 4E7N-A nrPDB 251 2e-67 5FCR-A nrPDB 251 2e-67 1VR1-H nrPDB 250 5e-67 1BDA-A nrPDB 250 5e-67 1EKB-B nrPDB 250 5e-67 1FON-A nrPDB 249 6e-67 1MZD-A nrPDB 249 7e-67 4IGD-A nrPDB 247 2e-66 2OCV-B nrPDB 247 3e-66 1A5I-A nrPDB 247 4e-66 1ETT-H nrPDB 246 6e-66 2BDH-A nrPDB 244 3e-65 1YC0-A nrPDB 244 3e-65 3F6U-H nrPDB 242 8e-65 1FIZ-A nrPDB 242 9e-65 5LHN-A nrPDB 240 3e-64 4Z6A-H nrPDB 240 3e-64 2OQ5-A nrPDB 240 5e-64 1Q3X-A nrPDB 240 5e-64 1SC8-U nrPDB 239 9e-64 1OP0-A nrPDB 238 2e-63 1FIW-A nrPDB 237 3e-63 1ZJK-A nrPDB 237 3e-63 2R0L-A nrPDB 237 5e-63 1BQY-A nrPDB 236 7e-63 4XDE-A nrPDB 236 8e-63 3S69-A nrPDB 235 1e-62 5TO3-B nrPDB 233 4e-62 2XXL-A nrPDB 233 6e-62 4DJZ-B nrPDB 232 1e-61 1AZZ-A nrPDB 231 2e-61 4Q7Y-A nrPDB 231 3e-61 5LPF-A nrPDB 229 9e-61 2OLG-A nrPDB 228 1e-60 4KKD-A nrPDB 226 7e-60 1GPZ-A nrPDB 226 8e-60 2ZKS-A nrPDB 226 9e-60 1MD7-A nrPDB 225 2e-59 5XRF-A nrPDB 223 4e-59 1AE5-A nrPDB 223 5e-59 4IW4-E nrPDB 222 1e-58 1EQ9-A nrPDB 222 1e-58 2QY0-B nrPDB 222 1e-58 4FXG-H nrPDB 220 6e-58 4BXW-A nrPDB 219 9e-58 1YM0-A nrPDB 219 1e-57 1ELV-A nrPDB 214 3e-56 5KWM-A nrPDB 213 6e-56 2XRC-A nrPDB 211 2e-55 5UBM-A nrPDB 211 2e-55 1PPF-E nrPDB 209 1e-54 4J1Y-A nrPDB 208 2e-54 5O32-I nrPDB 206 7e-54 2B9L-A nrPDB 206 8e-54 2HLC-A nrPDB 205 1e-53 6BQM-A nrPDB 203 8e-53 3I77-A nrPDB 201 2e-52 2ASU-B nrPDB 201 3e-52 4LK4-A nrPDB 197 3e-51 3BEU-A nrPDB 196 8e-51 1PQ7-A nrPDB 193 7e-50 4F4O-C nrPDB 191 2e-49 4WJG-C nrPDB 189 1e-48 2FMJ-A nrPDB 189 1e-48 4X0L-C nrPDB 188 2e-48 1SI5-H nrPDB 185 2e-47 5XW8-A nrPDB 181 3e-46 3H7O-A nrPDB 180 4e-46 1M9U-A nrPDB 178 3e-45 3H7T-A nrPDB 176 1e-44 2PKA-B nrPDB 170 5e-43 3VGC-B nrPDB 166 6e-42 2JET-B nrPDB 166 1e-41 1RIW-B nrPDB 157 4e-39 1BBR-H nrPDB 151 2e-37 2WIN-I nrPDB 144 3e-35 1DLE-A nrPDB 142 1e-34 2OK5-A nrPDB 140 4e-34 1AKS-B nrPDB 131 2e-31 2KAI-A nrPDB 119 8e-28 1EPT-B nrPDB 110 7e-25 3F1S-B nrPDB 102 1e-22 3RU4-E nrPDB 101 2e-22 2JET-C nrPDB 100 5e-22 3H5C-B nrPDB 100 1e-21 Sequences not found previously or not previously below threshold: 1BBR-E nrPDB 104 4e-23 2HNT-F nrPDB 104 5e-23 2I6S-A nrPDB 101 4e-22 2HNT-C nrPDB 80 9e-16 2HNT-E nrPDB 79 2e-15 1P3E-A nrPDB 41 7e-04 2PFE-A nrPDB 37 0.009 2OUA-A nrPDB 35 0.024 2EA3-A nrPDB 35 0.035 5ILB-A nrPDB 34 0.042 4FLN-A nrPDB 34 0.042 2SFA-A nrPDB 32 0.15 5JYK-A nrPDB 31 0.35 3LT3-A nrPDB 31 0.42 1DUE-A nrPDB 31 0.46 2SGA-A nrPDB 31 0.47 5ILA-A nrPDB 31 0.49 4NCX-A nrPDB 31 0.69 3TJO-A nrPDB 30 0.87 3NUM-A nrPDB 30 0.87 4V1Y-A nrPDB 30 0.91 3H7V-A nrPDB 30 0.97 4JCN-A nrPDB 29 2.3 4FVB-A nrPDB 29 2.4 3W95-A nrPDB 29 2.4 1HPG-A nrPDB 29 2.5 1Q2Q-A nrPDB 28 3.2 6F07-A nrPDB 28 3.3 3LEC-A nrPDB 28 3.5 2HRV-A nrPDB 28 3.5 6HQA-B nrPDB 28 3.7 4BF7-A nrPDB 28 4.5 4ASC-A nrPDB 27 7.9 >1NN6-A nrPDB Length = 228 Score = 342 bits (878), Expect = 8e-95, Method: Composition-based stats. Identities = 228/228 (100%), Positives = 228/228 (100%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 140 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF 199 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN Sbjct: 181 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 228 >1UTJ-A nrPDB Length = 242 Score = 313 bits (802), Expect = 5e-86, Method: Composition-based stats. Identities = 84/247 (34%), Positives = 132/247 (53%), Gaps = 13/247 (5%) Query: 6 LPLLLFLLCSRAEAG---EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVL 62 + L+ LL A A +I+GG ECKP+S+P+ L N FCGG L+ N+V+ Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSL-----NSGYHFCGGSLVNENWVV 56 Query: 63 TAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL 122 +AAHC + V LG HNI E + Q + + RHP Y++ + +DIML+KL + A+L Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATL 116 Query: 123 TLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDF 181 V + P+ + P G MC V+GWG T S+ LQ + + ++ C++ + Sbjct: 117 NTYVQPVALPT--SCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGM 174 Query: 182 DHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHYRPW 239 N C G K + +GDSGGP++C G QG+VS+G A+P P V+ ++ + W Sbjct: 175 ITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFNDW 234 Query: 240 INQILQA 246 + + + Sbjct: 235 LTSTMAS 241 >1EUF-A nrPDB Length = 227 Score = 310 bits (794), Expect = 4e-85, Method: Composition-based stats. Identities = 124/225 (55%), Positives = 150/225 (66%), Gaps = 2/225 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMA+L TS G S CGGFL+R +FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTS-GKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E E T Q + V + HP YN TL +DIMLLKL KA +T V + P V PG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAFK 200 MC VAGWGR GV P +D LQEV L + + C + F+++ Q+C G+P K K++F Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSFS 179 Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 GDSGGPL+C GVAQGIVSYGR+D P V+TRIS + WI+ ++ Sbjct: 180 GDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMR 224 >1FI8-A nrPDB Length = 228 Score = 307 bits (788), Expect = 2e-84, Method: Composition-based stats. Identities = 117/228 (51%), Positives = 154/228 (67%), Gaps = 2/228 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMAYL+I+ SK CGGFLIR +FVLTAAHC+G I VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E Q + V+K HP YN+ T+ +DIMLLKLK KA + AV L P + V PG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF--RDFDHNLQLCVGNPRKTKSAF 199 +C VAGWG+ G + SDTLQEV+L + + Q C + FD ++C G+P+ +++F Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 +GDSGGPL+C VA GIVSYG++D P FT++S + WI + ++ + Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 228 >1F7Z-A nrPDB Length = 233 Score = 307 bits (787), Expect = 3e-84, Method: Composition-based stats. Identities = 85/230 (36%), Positives = 118/230 (51%), Gaps = 11/230 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY L N FCGG LI +V++AAHC I V LG HNI Sbjct: 11 IVGGYTCQENSVPYQVSL-----NSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNI 65 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K +HP ++ TL++DIML+KL L V T+ PS + P G Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPS--SCAPAG 123 Query: 142 RMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAF 199 C ++GWG T D LQ + L+ C + + + +CVG K + Sbjct: 124 TQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSC 183 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQAN 247 +GDSGGP++C G QGIVS+G A P P V+T++ +Y WI + AN Sbjct: 184 QGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >5C67-A nrPDB Length = 224 Score = 304 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 83/230 (36%), Positives = 115/230 (50%), Gaps = 11/230 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY L N S FCGG LI +V++AAHC I V LG HNI Sbjct: 1 IVGGYTCEENSLPYQVSL-----NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K RHPKYN TL +DIML+KL A + V T+ P+ G Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP--AAG 113 Query: 142 RMCRVAGWGRT-GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAF 199 C ++GWG T D L+ + ++ C + + N CVG K + Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 + D+GGP++C G QG+VS+G A P V+T++ +Y WI + AN Sbjct: 174 QRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >4AN7-A nrPDB Length = 231 Score = 304 bits (779), Expect = 2e-83, Method: Composition-based stats. Identities = 86/232 (37%), Positives = 118/232 (50%), Gaps = 11/232 (4%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 +I+GG C +S PY L N S FCGG LI +V++AAHC I V LG H Sbjct: 7 DKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEH 61 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NI E Q + K HP +N +TL +DIML+KL A+L V T+ P + Sbjct: 62 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SCAA 119 Query: 140 PGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKS 197 G C ++GWG T LQ +K ++ +C S + +CVG K Sbjct: 120 AGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKD 179 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C G QGIVS+G A P V+T++ +Y WI Q + AN Sbjct: 180 SCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >5FXL-A nrPDB Length = 246 Score = 301 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 83/232 (35%), Positives = 121/232 (52%), Gaps = 11/232 (4%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 +I+GG C ++ PY L N FCGG LI +V++AAHC I V LG Sbjct: 22 DKIVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGED 76 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NI E Q + K HP YN++TL++DIML+KLK ASL V ++ P+ + Sbjct: 77 NINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCAS 134 Query: 140 PGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKS 197 G C ++GWG T D L+ +K ++ +C S + + C G K Sbjct: 135 AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKD 194 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C+G QGIVS+G A P V+T++ +Y WI Q + +N Sbjct: 195 SCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >1A0J-A nrPDB Length = 223 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 86/230 (37%), Positives = 125/230 (54%), Gaps = 11/230 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ +S Y A L+ FCGG LI +V++AAHC I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E T Q ++ +K HP YN+ L +DIML+KL + ASL V T+ PS + G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPS--SCASSG 113 Query: 142 RMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAF 199 C V+GWG +G DTL+ + L ++ +C+ + + C G K + Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 +GDSGGP++C G QG+VS+G A P V+T++ +YR WI+ + +N Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >4WWY-A nrPDB Length = 224 Score = 300 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 80/230 (34%), Positives = 115/230 (50%), Gaps = 11/230 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C+ +S PY L N FCGG LI +V++A HC I V LG HNI Sbjct: 1 IVGGYNCEENSVPYQVSL-----NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K RHP+Y+ TL++DIML+KL +A + V T+ P+ G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPP--ATG 113 Query: 142 RMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAF 199 C ++GWG T D LQ + ++ C + + + CVG K + Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 + DSGGP++C G QG+VS+G A P V+T++ +Y WI + AN Sbjct: 174 QRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1IAU-A nrPDB Length = 227 Score = 294 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 119/226 (52%), Positives = 147/226 (65%), Gaps = 3/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMAYL I K CGGFLIR +FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLMI-WDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E T Q + V + HP YN +DIMLL+L+ KA T AV L PS V PG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF--RDFDHNLQLCVGNPRKTKSAF 199 + C VAGWG+T L S TLQEVK+ + + + C +D ++LCVG+P K++F Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 KGDSGGPL+C VAQGIVSYGR++ PP T++S + WI + ++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 225 >2RDL-A nrPDB Length = 226 Score = 292 bits (748), Expect = 8e-80, Method: Composition-based stats. Identities = 160/226 (70%), Positives = 185/226 (81%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGGTEC+PH+RPYMAYLEIVT C GFLIRRNFV+TAAHCAGRSITV LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 +EDTWQKLEV KQF HPKY+ + +DIMLLKLKEKA+LTL VGTLP ++ N +PPG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKG 201 R+CR GWGRT V +P SDTLQEVK+R++DPQAC HF DF QLCVGNP+K ++ +KG Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRNVYKG 180 Query: 202 DSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 DSGGPLLCAG+AQGI SY +AKPP+VFTRISHYRPWIN+IL+ N Sbjct: 181 DSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILREN 226 >3RP2-A nrPDB Length = 224 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 134/224 (59%), Positives = 164/224 (73%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E PHSRPYMA+L+IVT G CGGFLI R FVLTAAHC GR ITV LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 + E T QK++V KQ H YN+ HDIMLLKL++K LT AV +P PS +F+ PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKG 201 MC AGWG+TGV P S TL+EV+LR+MD +AC +R +++ Q+CVG+P ++AF G Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRAAFMG 180 Query: 202 DSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 DSGGPLLCAGVA GIVSYG DAKPPA+FTR+S Y PWIN ++ Sbjct: 181 DSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVIN 224 >3G01-A nrPDB Length = 227 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 109/226 (48%), Positives = 136/226 (60%), Gaps = 2/226 (0%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E PHSRPYMAY E + G FCGGFL+R FVLTAAHC GRS+TVTLGAHNI Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 +E+T Q + V K HP YN +DIMLLKL A T AV L P + V PG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGNPRKTKSAF 199 C VAGWG+ TL EVKL + Q C ++ ++CVG+ + ++F Sbjct: 121 DECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASF 180 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 +GDSGGPL+C A GIVSYG++D P VFTR+ + WI + ++ Sbjct: 181 RGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >4NFE-A nrPDB Length = 237 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 93/242 (38%), Positives = 126/242 (52%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ + S+G + CGG L+ +VLTAAHC ++ V LG HN+ Sbjct: 1 IVGGWECEKHSQPWQVAVY---SHGWAH-CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGTLP 130 E EDT Q++ V F HP YN S L HD+MLL+L E A +T V L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC 188 P+Q + G C +GWG + +LQ V L L+ C+ + + LC Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQILQ 245 G K GDSGGPL+C GV QGI S+G + PAV+T++ HYR WI + Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 234 Query: 246 AN 247 AN Sbjct: 235 AN 236 >2TLD-E nrPDB Length = 220 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 83/229 (36%), Positives = 120/229 (52%), Gaps = 12/229 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG C ++ PY L N FCGG LI +V++AAHC I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E Q + K HP YN++TL++DIML+KLK ASL V ++ P+ + G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCASAG 113 Query: 142 RMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAF 199 C ++GWG T D L+ +K ++ +C S + + C G + Sbjct: 114 TQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE--GGDSC 171 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAK-PPAVFTRISHYRPWINQILQAN 247 +GDSGGP++C+G QGIVS+G AK P V+T++ +Y WI Q + +N Sbjct: 172 QGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTIASN 220 >1SGF-G nrPDB Length = 237 Score = 282 bits (722), Expect = 9e-77, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 120/242 (49%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG +C+ +S+P+ + T CGG L+ N+VLTAAHC + V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYT----QYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTST-----------LHHDIMLLKLKEKASLTLAVGTLP 130 ++E + Q V K HP +N S +D+MLL+L + A +T V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 131 FPSQFNFVPPGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFR-DFDHNLQLC 188 P++ + G C +GWG T +D L V L+L+ + C+ + + LC Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQ 245 G K KGDSGGPL+C GV QGI S+G + P V+T+++ + WI + Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 246 AN 247 N Sbjct: 235 KN 236 >2EEK-A nrPDB Length = 220 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 74/227 (32%), Positives = 115/227 (50%), Gaps = 10/227 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC HS+ + L N FCGG L+ +++V++AAHC + V LG H+I Sbjct: 1 IVGGYECTKHSQAHQVSL-----NSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHI 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E T Q + RHP Y++ +++DIML+KL + A+L V + P++ Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTE--CAADA 113 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAFK 200 MC V+GWG T D LQ + L ++ C + + C G K + + Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQ 245 GDSGGP++C GV QG+VS+G A+ P V+ ++ W+ + Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTMA 220 >3TK9-A nrPDB Length = 226 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 109/226 (48%), Positives = 145/226 (64%), Gaps = 4/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E KPHSRPYMA+++ + K CGG L+R++FVLTAAHC G SI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQ-EKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+E T Q + V + HP YN ++IMLL+L+ KA T AV L PS V PG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGNPRKTKSAF 199 ++C VAGWG + + TLQEV L + C ++ ++CVG+P+KT++ F Sbjct: 120 QLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 245 KGDSGGPL+C VAQGI+SYG PP V+ ++SH+ PWI + ++ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMK 224 >5TJX-A nrPDB Length = 263 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 68/248 (27%), Positives = 107/248 (43%), Gaps = 14/248 (5%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--- 69 +C+ + I+GGTE P+ L++ + CGG LI +VLTAAHC Sbjct: 7 VCTTKTSTRIVGGTESSWGEWPWQVSLQVKLT-AQRHLCGGSLIGHQWVLTAAHCFDGLP 65 Query: 70 --RSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVG 127 + G +++ ++ + H Y S +HDI L+KL+ T Sbjct: 66 LQDVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQK 125 Query: 128 TLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNL 185 + PS+ + C V GWG + + LQ+V + L+ + C Sbjct: 126 PISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 185 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYRPW 239 +C G K A KGDSGGPL+C GI S+G A+ P V+T+++ Y W Sbjct: 186 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 245 Query: 240 INQILQAN 247 I + Q++ Sbjct: 246 ILEKTQSS 253 >1FXY-A nrPDB Length = 228 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 108/232 (46%), Gaps = 11/232 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 I+GG CK P+ A L + G FCGG ++ ++LTAAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 N +EE EV +H ++ T DI +L+LK + + V P+ Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPP--A 115 Query: 140 PGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKS 197 G C ++GWG T D LQ + ++ C + + + CVG K Sbjct: 116 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKD 175 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 + +GDSGGP++C G QG+VS+G A P V+T++ +Y WI + AN Sbjct: 176 SCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >6I44-A nrPDB Length = 627 Score = 280 bits (717), Expect = 3e-76, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 107/248 (43%), Gaps = 14/248 (5%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--- 69 +C+ + I+GGT+ P+ L++ + CGG LI +VLTAAHC Sbjct: 371 VCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLT-AQRHLCGGSLIGHQWVLTAAHCFDGLP 429 Query: 70 --RSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVG 127 + G +++ ++ + H Y S +HDI L+KL+ T Sbjct: 430 LQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQK 489 Query: 128 TLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNL 185 + PS+ + C V GWG + + LQ+V + L+ + C Sbjct: 490 PICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 549 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYRPW 239 +C G K A KGD+GGPL+C GI S+G A+ P V+T+++ Y W Sbjct: 550 MVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 609 Query: 240 INQILQAN 247 I + Q++ Sbjct: 610 ILEKTQSS 617 >2F83-A nrPDB Length = 625 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 72/248 (29%), Positives = 106/248 (42%), Gaps = 14/248 (5%) Query: 12 LLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--- 68 C+ I+GGT P+ L TS CGG +I ++LTAAHC Sbjct: 378 NECTTKIKPRIVGGTASVRGEWPWQVTLH-TTSPTQRHLCGGSIIGNQWILTAAHCFYGV 436 Query: 69 --GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAV 126 + + V G N +E ++ V + H +Y + +DI LLKL+ + T + Sbjct: 437 ESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQ 496 Query: 127 GTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR--DFDHN 184 + PS+ + C V GWG + +TLQ+ K+ L+ + C + Sbjct: 497 RPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITH 556 Query: 185 LQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAK--PPAVFTRISHYRP 238 +C G K A KGDSGGPL C GI S+G A+ P V+T + Y Sbjct: 557 KMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616 Query: 239 WINQILQA 246 WI + QA Sbjct: 617 WILEKTQA 624 >1BRU-P nrPDB Length = 241 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 121/242 (50%), Gaps = 17/242 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAH 79 ++GG + +P+S P+ L+ +S CGG L+ +++VLTAAHC + R+ V LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 +++ E ++V K H +N++ L +DI LLKL SLT + P+ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF---DHNLQLCVGNPRK 194 +P +C V GWGR D LQ+ +L ++D CS + +C G Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG-DG 179 Query: 195 TKSAFKGDSGGPLLC-----AGVAQGIVSYGRSDA----KPPAVFTRISHYRPWINQILQ 245 S+ GDSGGPL C GIVS+G S P+VFTR+S+Y WIN ++ Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIA 239 Query: 246 AN 247 N Sbjct: 240 NN 241 >1SPJ-A nrPDB Length = 238 Score = 274 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 85/243 (34%), Positives = 121/243 (49%), Gaps = 23/243 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ A L + CGG L+ R +VLTAAHC + + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALYHF----STFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHH-----------DIMLLKLKEKA-SLTLAVGTL 129 ++E+T Q + V + F HP +N S L + D+MLL+L E A ++T AV + Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 130 PFPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFR-DFDHNLQL 187 P++ V G C +GWG D LQ V L+++ C + L Sbjct: 117 ELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFML 174 Query: 188 CVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQIL 244 CVG+ K GDSGGPL+C GV QG+ S+G P+V R+ Y WI + Sbjct: 175 CVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 Query: 245 QAN 247 N Sbjct: 235 AEN 237 >5GVT-A nrPDB Length = 250 Score = 273 bits (698), Expect = 5e-74, Method: Composition-based stats. Identities = 69/239 (28%), Positives = 108/239 (45%), Gaps = 14/239 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GGT P+ L++ + CGG +I R +VLTAAHC + Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLV-SQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G +++E + + H +Y S ++DI L+KL+ + T + PS+ + Sbjct: 60 GILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHN-LQLCVGNPRK 194 C V GWG T + LQ+ + L+ + C +RD+ N +C G Sbjct: 120 TNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 195 TKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQAN 247 A KGDSGGPL+C GI S+G A+ P V+T++S Y WI + Q++ Sbjct: 180 GTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSS 238 >1KYN-A nrPDB Length = 235 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 116/226 (51%), Positives = 152/226 (67%), Gaps = 3/226 (1%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG E +PHSRPYMAYL+I + G S+ CGGFL+R +FVLTAAHC G +I VTLGAHNI Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSR-CGGFLVREDFVLTAAHCWGSNINVTLGAHNI 59 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 E+T Q + + RHP+YN T+ +DIMLL+L + V + P + PG Sbjct: 60 QRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 142 RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFK 200 +C VAGWGR ++ G+DTL+EV+LR+ + C F +D Q+CVG+ R+ K+AFK Sbjct: 120 TLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFK 178 Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQA 246 GDSGGPLLC VA GIVSYG+S PP VFTR+S + PWI +++ Sbjct: 179 GDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRS 224 >3QUM-P nrPDB Length = 237 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 119/242 (49%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG EC+ HS+P+ + ++ CGG L+ +VLTAAHC + LG H++ Sbjct: 1 IVGGWECEKHSQPWQVLV----ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHH-----------DIMLLKLKEKASLTLAVGTLP 130 EDT Q +V F HP Y+ S L + D+MLL+L E A LT AV + Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC 188 P+Q + G C +GWG + LQ V L ++ C+ LC Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQILQ 245 G KS GDSGGPL+C GV QGI S+G + P+++T++ HYR WI + Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 234 Query: 246 AN 247 AN Sbjct: 235 AN 236 >1PYT-D nrPDB Length = 251 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 85/251 (33%), Positives = 117/251 (46%), Gaps = 15/251 (5%) Query: 9 LLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA 68 + + ++GG + PHS P+ L+ + N CGG LI N VLTAAHC Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 69 GRS--ITVTLGAHNI-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125 + V LG +N+ E+E + V F H K+N+ + +DI L+KL E L Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDT 120 Query: 126 VGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH-- 183 + PS+ + +P C V GWGR P + LQ+ ++D CS + Sbjct: 121 IQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTV 180 Query: 184 -NLQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDA----KPPAVFTRIS 234 +C G SA GDSGGPL C +GIVS+G + K P VFTR+S Sbjct: 181 KETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVS 239 Query: 235 HYRPWINQILQ 245 Y WINQ LQ Sbjct: 240 AYIDWINQKLQ 250 >4H4F-A nrPDB Length = 249 Score = 267 bits (683), Expect = 3e-72, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 118/239 (49%), Gaps = 16/239 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 79 ++GG + +PHS P+ L+ + ++ CGG LI NFVLTAAHC R+ V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 80 NI-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 N+ E+E+ + V H ++N L +DI L+KL E L+ + P + + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 139 PPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF---DHNLQLCVGNPRKT 195 P C V GWGR P +D LQ+ ++D CS + +C G Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 179 Query: 196 KSAFKGDSGGPLLCA-----GVAQGIVSY----GRSDAKPPAVFTRISHYRPWINQILQ 245 SA GDSGGPL C GIVS+ G + K P V+TR+S Y WIN+ +Q Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >5MS3-A nrPDB Length = 228 Score = 267 bits (683), Expect = 3e-72, Method: Composition-based stats. Identities = 80/233 (34%), Positives = 124/233 (53%), Gaps = 15/233 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG EC+PHS+P+ A L G CGG L+ N+VLTAAHC TV LG H++ Sbjct: 1 VLGGHECQPHSQPWQAAL----FQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNT---STLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 ++ Q++ V++ HP YN+ +HD+MLL+L+++ASL V + + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--ADHCT 114 Query: 139 PPGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTK 196 PG+ C V+GWG T + DTL ++++ + C + + +C G+ + Sbjct: 115 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA- 173 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYGRSDAK---PPAVFTRISHYRPWINQILQA 246 +GDSGGPL+C G QGI S+G P V+T I Y WI +I+ + Sbjct: 174 DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 226 >5UGG-A nrPDB Length = 251 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 113/242 (46%), Gaps = 24/242 (9%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITV 74 G ++GG PHS P+ L FCGG LI +VLTAAHC +S V Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRF---GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 76 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGAH E Q++EV + F P DI LLKL A +T V PS Sbjct: 77 ILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSP 130 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQLCVGN 191 V C + GWG T G+ L+E +L +++ + C+ + + +LC G+ Sbjct: 131 NYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGH 189 Query: 192 PRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 245 + +GDSGGPL+C + QG+ S+G A+ P V+ R+S + WI +++ Sbjct: 190 LAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 249 Query: 246 AN 247 N Sbjct: 250 NN 251 >1X7A-C nrPDB Length = 235 Score = 266 bits (680), Expect = 7e-72, Method: Composition-based stats. Identities = 74/237 (31%), Positives = 106/237 (44%), Gaps = 17/237 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 I+GG KP P+ L + FCGG +I +V+TAAHC G ITV G + Sbjct: 1 IVGGENAKPGQFPWQVLL----NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEY 56 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNT--STLHHDIMLLKLKEKASLTLAVGTLPFPSQF-- 135 N E E T Q+ VI+ H YN + HDI LL+L E +L V + + Sbjct: 57 NTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYT 116 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRK 194 N V+GWGR + LQ +K+ L+D C F ++ C G Sbjct: 117 NIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEG 176 Query: 195 TKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQ 245 K + +GDSGGP + GI+S+G A ++T++S Y WI + + Sbjct: 177 GKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >4DUR-A nrPDB Length = 791 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 113/242 (46%), Gaps = 24/242 (9%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITV 74 G ++GG PHS P+ L FCGG LI +VLTAAHC +S V Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRF---GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 616 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGAH E Q++EV + F P DI LLKL A +T V PS Sbjct: 617 ILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSP 670 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQLCVGN 191 V C + GWG T G+ L+E +L +++ + C+ + + +LC G+ Sbjct: 671 NYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGH 729 Query: 192 PRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 245 + +GDSGGPL+C + QG+ S+G A+ P V+ R+S + WI +++ Sbjct: 730 LAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 789 Query: 246 AN 247 N Sbjct: 790 NN 791 >3LC3-A nrPDB Length = 235 Score = 264 bits (675), Expect = 2e-71, Method: Composition-based stats. Identities = 73/237 (30%), Positives = 108/237 (45%), Gaps = 17/237 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 ++GG + KP P+ L + FCGG ++ +++TAAHC G ITV G H Sbjct: 1 VVGGEDAKPGQFPWQVVL----NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEH 56 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNT--STLHHDIMLLKLKEKASLTLAVGTLPFPSQF-- 135 NI E E T QK VI+ H YN + +HDI LL+L E L V + + Sbjct: 57 NIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYT 116 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQLCVGNPRK 194 N V+GWGR + LQ +++ L+D C F +N C G Sbjct: 117 NIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEG 176 Query: 195 TKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQ 245 + + +GDSGGP + GI+S+G A ++T++S Y WI + + Sbjct: 177 GRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >2V35-A nrPDB Length = 240 Score = 263 bits (673), Expect = 4e-71, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 16/241 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGR--SITVTLGAH 79 ++GGTE + +S P L+ + + + CGG LIR+N+V+TAAHC R + V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTL--HHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 N+ + + T Q + V K HP +NT + +DI LL+L + +L V P Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC---SHFRDFDHNLQLCVGNPRK 194 + C + GWG T + TLQ+ L +D C S++ N +C G Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG-DG 179 Query: 195 TKSAFKGDSGGPLLC----AGVAQGIVSY----GRSDAKPPAVFTRISHYRPWINQILQA 246 +S +GDSGGPL C G+ S+ G + + P VFTR+S Y WIN ++ + Sbjct: 180 VRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIAS 239 Query: 247 N 247 N Sbjct: 240 N 240 >1AO5-A nrPDB Length = 237 Score = 263 bits (673), Expect = 4e-71, Method: Composition-based stats. Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG C+ +S+P+ + CGG L+ RN+VLTAAHC V LG + + Sbjct: 1 VVGGFNCEKNSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGTLP 130 +EE + Q V K F HP +N S L D+MLL+L + A +T V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFR-DFDHNLQLC 188 P++ PG C +GWG + D LQ V + L+ + C+ ++ LC Sbjct: 117 LPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAV---FTRISHYRPWINQILQ 245 G K + DSGGPL+C G+ QG SYG P V +T + + WI + Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 234 Query: 246 AN 247 N Sbjct: 235 KN 236 >1NPM-A nrPDB Length = 225 Score = 263 bits (672), Expect = 5e-71, Method: Composition-based stats. Identities = 73/232 (31%), Positives = 114/232 (49%), Gaps = 15/232 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+ G EC PHS+P+ A L G CGG L+ +VLTAAHC + +V LG H++ Sbjct: 1 ILEGRECIPHSQPWQAAL----FQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYN---TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 138 + Q+++V + +HP YN HDIML++L+ A+L V + Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLCP 114 Query: 139 PPGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTK 196 G+ C ++GWG T + +TL ++++ C + +C G+ Sbjct: 115 KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGA- 173 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQ 245 +GDSGGPL+C G+ QGI S+G + P V+T+I Y WI + + Sbjct: 174 DTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMD 225 >3T2N-A nrPDB Length = 372 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 68/263 (25%), Positives = 110/263 (41%), Gaps = 29/263 (11%) Query: 10 LFLLCSRAE--AGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC 67 + C R + I+GG + P+ L + CGG L+ ++VLTAAHC Sbjct: 104 ICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWVLTAAHC 159 Query: 68 AGRSITV----TLGAHNITEEEDTWQKLEVIKQFRHPKY------NTSTLHHDIMLLKLK 117 V + A + + +L V H Y N+ +DI L+ L Sbjct: 160 FPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLS 219 Query: 118 EKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH 177 LT + + P+ + G++C V GWG T + LQE ++ ++ C+ Sbjct: 220 SPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG 279 Query: 178 FRDFDHNL---QLCVGNPRKTKSAFKGDSGGPLLCA--------GVAQGIVSYGRSD--A 224 + + + C G P A +GDSGGP +C GIVS+G A Sbjct: 280 ADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALA 339 Query: 225 KPPAVFTRISHYRPWINQILQAN 247 + P V+T++S +R WI Q ++ + Sbjct: 340 QKPGVYTKVSDFREWIFQAIKTH 362 >6QHB-A nrPDB Length = 223 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 73/228 (32%), Positives = 113/228 (49%), Gaps = 11/228 (4%) Query: 23 IGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNIT 82 + G C S PY A L CGG LI +VLTAAHC ++ V LG HN+ Sbjct: 2 VHGGPCDKTSHPYQAALYT----SGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLG 57 Query: 83 EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGR 142 ++E + ++ V++ HP Y+ ++ DIMLL+L A L+ + P + + Sbjct: 58 QQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTT 115 Query: 143 MCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFKG 201 C + GWG+T DT+Q + L+ + C H + LC G+ + K + +G Sbjct: 116 SCHILGWGKTA-DGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQG 174 Query: 202 DSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQA 246 DSGGPL+C +G+VS+G + P V+T + Y WI + +QA Sbjct: 175 DSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 222 >3W94-A nrPDB Length = 235 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 104/237 (43%), Gaps = 19/237 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT------VT 75 ++GG + + P+M L +G CG LI R+++LTAAHC T Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHG----CGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 76 LGAHNITE-EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LG H + Q +V + + YN T DI ++ L++ + T V + S+ Sbjct: 57 LGLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASE 116 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGNP 192 P GR C +AGWGR D LQE ++ L+D C + LC G P Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYP 176 Query: 193 RKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQI 243 + +GDSGGPL+C G+ S+G +P P + R+S + WI + Sbjct: 177 EGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAET 233 >2CGA-A nrPDB Length = 245 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 82/250 (32%), Positives = 113/250 (45%), Gaps = 16/250 (6%) Query: 9 LLFLLCSRAEAG--EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAH 66 +G I+ G E P S P+ L+ T FCGG LI N+V+TAAH Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKT---GFHFCGGSLINENWVVTAAH 57 Query: 67 C-AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125 C S V G + + QKL++ K F++ KYN+ T+++DI LLKL AS + Sbjct: 58 CGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQT 117 Query: 126 VGTLPFPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFRDF-DH 183 V + PS + G C GWG T D LQ+ L L+ C + Sbjct: 118 VSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIK 177 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYR 237 + +C G S+ GDSGGPL+C GIVS+G S P V+ R++ Sbjct: 178 DAMICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALV 235 Query: 238 PWINQILQAN 247 W+ Q L AN Sbjct: 236 NWVQQTLAAN 245 >6AOD-C nrPDB Length = 245 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 69/238 (28%), Positives = 102/238 (42%), Gaps = 14/238 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-----GRSITVTL 76 I+GGT P+ L TS CGG +I ++LTAAHC + + V Sbjct: 1 IVGGTASVRGEWPWQVTLH-TTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G +E ++ V + H +Y + +DI LLKL+ T + + PS+ + Sbjct: 60 GILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR--DFDHNLQLCVGNPRK 194 C V GWG + +TLQ+ K+ L+ + C + +C G Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 195 TKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQA 246 K A KGD+GGPL C GI S+G A+ P V+T + Y WI + QA Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQA 237 >3BSQ-A nrPDB Length = 227 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 85/229 (37%), Positives = 120/229 (52%), Gaps = 13/229 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G C S P+ L +G CGG L+ +VLTAAHC TV LG+ + Sbjct: 1 IIDGAPCARGSHPWQVAL----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 + Q+++ K FRHP Y+T T +D+ML+KL +A L+ V + PS+ PPG Sbjct: 57 GDRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 112 Query: 142 RMCRVAGWGRT-GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAF 199 C V+GWG T L V ++L+ PQ C+ ++D N LC G P K+A Sbjct: 113 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 172 Query: 200 KGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQ 245 GDSGGPL+C G QG+VS+G P V+T++ + WIN ++ Sbjct: 173 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1TON-A nrPDB Length = 235 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 24/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 I+GG +C+ +S+P+ + CGG LI ++V+TAAHC + V LG +N+ Sbjct: 1 IVGGYKCEKNSQPWQVAVI------NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNL 54 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTS-----------TLHHDIMLLKLKEKASLTLAVGTLP 130 ++E Q+ V + FRHP Y +D+MLL L E A +T V + Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLC 188 P++ V G C +GWG T + S LQ V + L+ + C ++D ++ LC Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP---PAVFTRISHYRPWINQILQ 245 G K GDSGGPL+C GV QGI S G + PA++ ++ + WI ++++ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 246 AN 247 N Sbjct: 233 EN 234 >1KIG-H nrPDB Length = 241 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 109/237 (45%), Gaps = 15/237 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 79 I+GG +C P+ A L + G FCGG ++ +VLTAAHC + TV +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG---FCGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF---N 136 N +EE EV +H ++ T DI +L+LK V P + Sbjct: 58 NTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEA 117 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN-LQLCVGNPRKT 195 + + V+G+GRT S TL+ +++ +D C F C G + Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQP 177 Query: 196 KSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWINQILQA 246 + A +GDSGGP + GIVS+G A+ V+T++S++ WI++I++A Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKA 234 >2F91-A nrPDB Length = 237 Score = 258 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 66/235 (28%), Positives = 101/235 (42%), Gaps = 17/235 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-------GRSITV 74 I+GGT+ PY + FCG + N+ +TA HC + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 G +++ E + Q + V K H ++ + L +DI LLKL + V + P Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH--NLQLCVGNP 192 + V GWG T D LQ+V + L+ + C D + +C G P Sbjct: 121 GHT--ATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 193 RKTKSAFKGDSGGPLLCAG----VAQGIVSYGRSDAKP--PAVFTRISHYRPWIN 241 K + +GDSGGPL + GIVS+G A+P P V+T +S++ WI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >1ORF-A nrPDB Length = 234 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 94/236 (39%), Positives = 133/236 (56%), Gaps = 15/236 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-AGRSITVTLGAHN 80 IIGG E PHSRPYM L + C G LI +++VLTAAHC + V LGAH+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRK----TICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 56 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 IT EE T Q + V K+F +P Y+ +T D+ LL+L EKA + V L P + + V P Sbjct: 57 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKP 116 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN-----LQLCVGNPRKT 195 G MC+VAGWGRT SDTL+EV++ ++D + C+ ++ N +C G+ R Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYG----RSDAKPPAVFTRIS-HYRPWINQILQA 246 + + GDSG PLLC GV +G+ S+G D + P V+ +S + WI ++ Sbjct: 177 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 232 >1FDP-A nrPDB Length = 235 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 84/236 (35%), Positives = 129/236 (54%), Gaps = 16/236 (6%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA----GRSITVT 75 G I+GG E + H+RPYMA +++ + CGG L+ +VL+AAHC + V Sbjct: 6 GRILGGREAEAHARPYMASVQL----NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVL 61 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 LGAH++++ E + + +V++ HP T+ HD++LL+L EKA+L AV LP+ Sbjct: 62 LGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVD 121 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS---HFRDFDHNLQLCVGNP 192 V PG +C VAGWG D+LQ V L ++D C+ H +C Sbjct: 122 RDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--E 179 Query: 193 RKTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQ 245 + + KGDSGGPL+C GV +G+V+ G + K P ++TR++ Y WI+ +L Sbjct: 180 SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >4MPW-A nrPDB Length = 245 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 76/244 (31%), Positives = 116/244 (47%), Gaps = 30/244 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS------ITVT 75 I+GG E P+ L + FCGG LI +VLTAAHC G + V Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPY-WMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 59 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 L ++ ++ Q L V + HP++ T+ + DI LL+L+E ++ V T+ P Sbjct: 60 LREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPAS 116 Query: 136 NFVPPGRMCRVAGWGRTGVLK--PGSDTLQEVKLRLMDPQACSHFRD----------FDH 183 PPG C V GWG + P L++VK+ +M+ C Sbjct: 117 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 176 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYR 237 + LC GN R + + +GDSGGPL+C + G+VS+G A+P P ++TR+++Y Sbjct: 177 DDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 234 Query: 238 PWIN 241 WI+ Sbjct: 235 DWIH 238 >4GSO-A nrPDB Length = 232 Score = 255 bits (653), Expect = 9e-69, Method: Composition-based stats. Identities = 74/232 (31%), Positives = 107/232 (46%), Gaps = 13/232 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG EC + P++A+L FCG LI + +V+TAAHC + + LG H+ Sbjct: 1 VLGGDECDINEHPFLAFLY-----SHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSK 55 Query: 82 TEEEDTWQKLEVIKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + Q ++F P N + L DIML+KL + S + + L PS V Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV-- 113 Query: 141 GRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNPRKTKSA 198 G +CR+ GWG T + D + L+D + C + LC G K Sbjct: 114 GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDT 173 Query: 199 FKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C G QGIVSYG P ++T + Y WI + + N Sbjct: 174 CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >3K65-B nrPDB Length = 308 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 106/259 (40%), Gaps = 35/259 (13%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 48 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 70 RSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 165 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGRTGV------LKPGSDTLQEVKLRLMDPQACSHF 178 + P + + + G RV GWG K LQ V L +++ C Sbjct: 166 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 225 Query: 179 -RDFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--P 226 R + C G P + K A +GD+GGP + GIVS+G + Sbjct: 226 TRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 285 Query: 227 PAVFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 286 YGFYTHVFRLKKWIQKVID 304 >2AIQ-A nrPDB Length = 231 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 71/231 (30%), Positives = 104/231 (45%), Gaps = 12/231 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 +IGG EC + ++A + S CGG LI + +VLTA HC ++ + LG HN+ Sbjct: 1 VIGGDECNINEHRFLALVYANGS-----LCGGTLINQEWVLTARHCDRGNMRIYLGMHNL 55 Query: 82 TE-EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 +D ++ K F N + DIML++L + + L PS V Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV-- 113 Query: 141 GRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAF 199 G +CR+ GWG T D + ++D C LC G K Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGKDTC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQILQAN 247 KGDSGGPL+C G QGI+S G + + P ++T++ Y WI I+ N Sbjct: 174 KGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >1MKW-K nrPDB Length = 308 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 71/266 (26%), Positives = 106/266 (39%), Gaps = 35/266 (13%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----- 67 L G I+ G + + P+ L + CG LI +VLTAAHC Sbjct: 41 LFESYIEGRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPP 98 Query: 68 AGRSIT-----VTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKA 120 ++ T V +G H+ T E +K+ + K + HP+YN L DI LLKLK Sbjct: 99 WDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPI 158 Query: 121 SLTLAVGTLPFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMD 171 L+ + + P + + G RV GWG T V + LQ V L L++ Sbjct: 159 ELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVE 218 Query: 172 PQAC-SHFRDFDHNLQLCVGNPRK---TKSAFKGDSGGPLLCA------GVAQGIVSYGR 221 C + R + C G A +GDSGGP + GIVS+G Sbjct: 219 RPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE 278 Query: 222 SDAK--PPAVFTRISHYRPWINQILQ 245 + +T + + WI +++ Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVID 304 >4DGJ-A nrPDB Length = 235 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 63/239 (26%), Positives = 103/239 (43%), Gaps = 21/239 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA------GRSITVT 75 I+GG++ K + P++ L CG L+ +++++AAHC T Sbjct: 1 IVGGSDAKEGAWPWVVGLYY----DDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 76 LGAHNITEEEDTWQKLE--VIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 LG H + + Q + + + +P YN +DI ++ L+ K + T + + P Sbjct: 57 LGLH-MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPE 115 Query: 134 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGN 191 + PPGR C +AGWG +D LQE + L+ + C +C G Sbjct: 116 ENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY 175 Query: 192 PRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQIL 244 + +GDSGGPL+C G+ S+G A P V+ R+S + WI L Sbjct: 176 EEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQSFL 234 >1P57-B nrPDB Length = 255 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 106/249 (42%), Gaps = 27/249 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITV----TLG 77 I+GG + P+ L + CGG L+ ++VLTAAHC V + Sbjct: 1 IVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKY------NTSTLHHDIMLLKLKEKASLTLAVGTLPF 131 A + + +L V H Y N+ +DI L+ L LT + + Sbjct: 57 AGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 116 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QLC 188 P+ + G++C V GWG T + LQE ++ ++ C+ + + + C Sbjct: 117 PAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFC 176 Query: 189 VGNPRKTKSAFKGDSGGPLLCA--------GVAQGIVSYGRSD--AKPPAVFTRISHYRP 238 G P A +GDSGGP +C GIVS+G A+ P V+T++S +R Sbjct: 177 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE 236 Query: 239 WINQILQAN 247 WI Q ++ + Sbjct: 237 WIFQAIKTH 245 >2PSX-A nrPDB Length = 227 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 69/232 (29%), Positives = 117/232 (50%), Gaps = 12/232 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G++C H++P+ A L + + +CG L+ ++LTAAHC + V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPN---QLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSL 57 Query: 82 T-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + E Q + +K HP Y+ +D+ML+KL + T V + S Sbjct: 58 SPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS--A 115 Query: 141 GRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSA 198 G C V+GWG T + LQ + + ++ + C + + C G+ + + + Sbjct: 116 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 174 Query: 199 FKGDSGGPLLCAGVAQGIVSYGR-SDAKP--PAVFTRISHYRPWINQILQAN 247 +GDSGGP++C G QG+VS+G A+P P V+T + + WI + +QAN Sbjct: 175 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3NXP-A nrPDB Length = 424 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 106/259 (40%), Gaps = 35/259 (13%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 164 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 70 RSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 281 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGRTGV------LKPGSDTLQEVKLRLMDPQACSHF 178 + P + + + G RV GWG K LQ V L +++ C Sbjct: 282 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 341 Query: 179 -RDFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--P 226 R + C G P + K A +GDSGGP + GIVS+G + Sbjct: 342 TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 401 Query: 227 PAVFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 402 YGFYTHVFRLKKWIQKVID 420 >1SGF-A nrPDB Length = 240 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 73/237 (30%), Positives = 113/237 (47%), Gaps = 23/237 (9%) Query: 27 ECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEED 86 +C+ +S+P+ + CGG L+ RN+VLTAAHC V LG +N E+E Sbjct: 10 DCE-NSQPWHVAVYRFNKYQ----CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEP 64 Query: 87 TWQKLEVIKQFRHPKYNT-----------STLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 + Q V K HP +N +D+MLL+L + A +T V + P++ Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEE 124 Query: 136 NFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFRDF-DHNLQLCVGNPR 193 + G C +GWG T +K D LQ V L+L+ + C + + LC G Sbjct: 125 PKL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMD 182 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 + DSGGPL+C G+ QGI S+G + P+V+T++ + WI + + N Sbjct: 183 GGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >1C5M-D nrPDB Length = 255 Score = 254 bits (649), Expect = 2e-68, Method: Composition-based stats. Identities = 64/237 (27%), Positives = 108/237 (45%), Gaps = 15/237 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAH 79 I+GG ECK P+ A L + G FCGG ++ ++LTAAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF---N 136 N +EE EV +H ++ T DI +L+LK + + V P + + Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 117 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNPRKT 195 + + V+G+GRT S L+ +++ +D +C C G K Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQ 177 Query: 196 KSAFKGDSGGPLLC----AGVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQA 246 + A +GDSGGP + GIVS+G A+ ++T+++ + WI++ ++ Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 234 >1ELT-A nrPDB Length = 236 Score = 253 bits (648), Expect = 3e-68, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 17/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 79 ++GG +P+S P+ L+ + + CGG LIR+ +V+TAAHC R+ V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTL--HHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 N+ E Q + V F H +N+ + +DI LL+L +ASL AV P Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF---DHNLQLCVGNPRK 194 +P C + GWG+T P SD+L++ L +D CS + +C G Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG--G 178 Query: 195 TKSAFKGDSGGPLLCA--------GVAQGIVSYGRSDAKPPAVFTRISHYRPWINQIL 244 S GDSGGPL C GV + S G + +K P VFTR+S Y W+N I+ Sbjct: 179 ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >5ZFH-A nrPDB Length = 224 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 77/231 (33%), Positives = 114/231 (49%), Gaps = 13/231 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G +CK S P+ L G CGG L+ + +VLTAAHC V LG+ I Sbjct: 1 IIDGYKCKEGSHPWQVAL----LKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKI 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPG 141 + + QK++ K FRHP Y+T T +DIML++L E ++ V + P PPG Sbjct: 57 --GDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPG 112 Query: 142 RMCRVAGWGRT-GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAF 199 C V+GWG T L ++L+ + C ++D LC G P + Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTC 172 Query: 200 KGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C QG+VS+G P V+T++ Y+ W+ + ++ + Sbjct: 173 NGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >3E0N-B nrPDB Length = 271 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 94/247 (38%), Gaps = 26/247 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-----GRSITVTL 76 I GG+ P+ + CGG L+ +VL+AAHC + V L Sbjct: 1 ITGGSSAVAGQWPWQVSITYE----GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 GAH + + + + HP Y DI LL+L + + + + P+ Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQA 116 Query: 137 FVPPGRMCRVAGWGRTGVLKP--GSDTLQEVKLRLMDPQACSHFR---------DFDHNL 185 P G C V GWG LQ++++ L+ + C+ F Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQED 176 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPW 239 +C G K A +GDSGGPL C GIVS+G + P V+T S Y W Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 240 INQILQA 246 I + Sbjct: 237 IQSKVTE 243 >3P8G-A nrPDB Length = 241 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 106/240 (44%), Gaps = 22/240 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA----------GRS 71 ++GGT+ P+ L + G CG LI N++++AAHC Sbjct: 1 VVGGTDADEGEWPWQVSLHAL---GQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 72 ITVTLGAHNITEEE-DTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLP 130 T LG H+ ++ Q+ + + HP +N T +DI LL+L++ A + V + Sbjct: 58 WTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPIC 117 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCV 189 P + P G+ V GWG T G+ LQ+ ++R++ C + +CV Sbjct: 118 LPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCV 177 Query: 190 GNPRKTKSAFKGDSGGPLLCAG-----VAQGIVSYGRSDA--KPPAVFTRISHYRPWINQ 242 G + +GDSGGPL G+VS+G A P V+TR+ +R WI + Sbjct: 178 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 237 >4NZQ-A nrPDB Length = 557 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 106/259 (40%), Gaps = 35/259 (13%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 G I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 297 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 70 RSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 414 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGRTGV------LKPGSDTLQEVKLRLMDPQACSHF 178 + P + + + G RV GWG K LQ V L +++ C Sbjct: 415 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 474 Query: 179 -RDFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--P 226 R + C G P + K A +GDSGGP + GIVS+G + Sbjct: 475 TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 534 Query: 227 PAVFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 535 YGFYTHVFRLKKWIQKVID 553 >3DFJ-A nrPDB Length = 263 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 94/247 (38%), Gaps = 26/247 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-----GRSITVTL 76 I GG+ P+ + CGG L+ +VL+AAHC + V L Sbjct: 1 ITGGSSAVAGQWPWQVSITYE----GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 GAH + + + + HP Y DI LL+L + + + + P+ Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANA 116 Query: 137 FVPPGRMCRVAGWGRTGVLKP--GSDTLQEVKLRLMDPQACSHFR---------DFDHNL 185 P G C V GWG LQ++++ L+ + C+ F Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQED 176 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPW 239 +C G K A +GDSGGPL C GIVS+G + P V+T S Y W Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 240 INQILQA 246 I + Sbjct: 237 IQSKVTE 243 >1GVZ-A nrPDB Length = 237 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 125/242 (51%), Gaps = 22/242 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG EC+ HS+P+ + + CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPWQVAVY----HQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGTLP 130 +++EDT Q +V F P+++ S L HD+MLL+L + A +T AV L Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 131 FPSQFNFVPPGRMCRVAGWGRTGV-LKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC 188 P+Q + G C +GWG GS TLQ V+LRL + C+ + + LC Sbjct: 117 LPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLC 174 Query: 189 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQILQ 245 + + S GDSGG L+C GV QGI S+G S+ VFT++ ++ WI + ++ Sbjct: 175 ATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIE 234 Query: 246 AN 247 N Sbjct: 235 KN 236 >1LTO-A nrPDB Length = 245 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 74/244 (30%), Positives = 114/244 (46%), Gaps = 30/244 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG------RSITVT 75 I+GG E P+ L + FCGG LI +VLTAAHC G ++ V Sbjct: 1 IVGGQEAPRSKWPWQVSLRVR-DRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQ 59 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 L ++ ++ Q L V + HP++ DI LL+L+E +++ V T+ P Sbjct: 60 LREQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPAS 116 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSD--TLQEVKLRLMDPQACSHFRD----------FDH 183 PPG C V GWG +P L++VK+ +M+ C Sbjct: 117 ETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIR 176 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAKP--PAVFTRISHYR 237 + LC GN + + + KGDSGGPL+C + G+VS+ A+P P ++TR+++Y Sbjct: 177 DDMLCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYL 234 Query: 238 PWIN 241 WI+ Sbjct: 235 DWIH 238 >3S9B-A nrPDB Length = 234 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 108/232 (46%), Gaps = 11/232 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 ++GG EC + P++ L TS + C G LI R +VLTAAHC R+I + LG H+ Sbjct: 1 VVGGDECNINEHPFLVALY--TSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSK 58 Query: 82 T-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ED ++ K F + L DIML++L+ + + + + PS+ V Sbjct: 59 NIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV-- 116 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH--NLQLCVGNPRKTKSA 198 G CR+ GWG+ D + ++ + C + + LC G + + Sbjct: 117 GSRCRIMGWGKISTTTY-PDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDT 175 Query: 199 FKGDSGGPLLCAGVAQGIVSYGRSDAK---PPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C G GIV+ G PAV+T++ Y WI I+ N Sbjct: 176 CHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >1FUJ-A nrPDB Length = 221 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 91/231 (39%), Positives = 124/231 (53%), Gaps = 17/231 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTLG 77 I+GG E +PHSRPYMA L++ + G S FCGG LI +FVLTAAHC R + V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AHN+ +E T Q V + F Y+ +DI+L++L A+L+ +V T+ P Q Sbjct: 60 AHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKS 197 VP G C GWGR G P + LQE+ + ++ F +C PR+ Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT--------FFCRPHNICTFVPRRKAG 170 Query: 198 AFKGDSGGPLLCAGVAQGI---VSYGRSDAKPPAVFTRISHYRPWINQILQ 245 GDSGGPL+C G+ QGI V +G + P FTR++ Y WI L+ Sbjct: 171 ICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >4E7N-A nrPDB Length = 238 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 72/235 (30%), Positives = 105/235 (44%), Gaps = 13/235 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG EC + ++ L TS + FCGG LI + +VLTAAHC ++ + LG H+ Sbjct: 1 IIGGDECNINEHRFLVALY--TSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSK 58 Query: 82 TE-EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ED ++ K F N + DIML++L + + + Sbjct: 59 KVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPPSV 116 Query: 141 GRMCRVAGWGRTGVL-KPGSDTLQEVKLRLMDPQACSHFRD----FDHNLQLCVGNPRKT 195 G +CR+ GWGR D V + L++ + C + LC G Sbjct: 117 GSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGG 176 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 K KGDSGGPL+C G QGI S+G + PA +T++ + WI I+ N Sbjct: 177 KDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGN 231 >5FCR-A nrPDB Length = 234 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 77/237 (32%), Positives = 117/237 (49%), Gaps = 17/237 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVTL 76 I+GG E H+RPYMA +++ + CGG L+ +VL+AAHC S+ V L Sbjct: 1 ILGGQEAAAHARPYMASVQV----NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 GAH+++ E + +V HP +L D++L KL + ASL V LP + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS---HFRDFDHNLQLCVGNPR 193 V PG +C VAGWG D L ++++ +M+ C+ + +C Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ES 174 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 + +GDSG PL+C +G+V++G + K P V+TR+S YR WI I N Sbjct: 175 NRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >1VR1-H nrPDB Length = 261 Score = 250 bits (638), Expect = 5e-67, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 106/259 (40%), Gaps = 35/259 (13%) Query: 22 IIGGTECKPHSRPYMAYL--EIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AG 69 I+ G++ + P+ L + S G CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 70 RSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVG 127 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 128 TLPFPSQ---FNFVPPGRMCRVAGWGRTGV------LKPGSDTLQEVKLRLMDPQACSHF 178 + P + + + G RV GWG K LQ V L +++ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 179 -RDFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--P 226 R + C P + K A +GDSGGP + GIVS+G + Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 240 Query: 227 PAVFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 241 YGFYTHVFRLKKWIQKVID 259 >1BDA-A nrPDB Length = 265 Score = 250 bits (638), Expect = 5e-67, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 111/252 (44%), Gaps = 27/252 (10%) Query: 21 EIIGGTECKPHSRPYMAYL--EIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI-----T 73 I GG S P+ A + + S G CGG LI ++L+AAHC T Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 74 VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEK----ASLTLAVGTL 129 V LG + QK EV K H +++ T +DI LL+LK A + V T+ Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 130 PFPSQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSH---FRDFDHNL 185 P +P C ++G+G+ L P S+ L+E +RL C+ + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 186 QLCVGNPRKTK------SAFKGDSGGPLLCAG----VAQGIVSYGRSDAKP--PAVFTRI 233 LC G+ R A +GDSGGPL+C GI+S+G + P V+T++ Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKV 252 Query: 234 SHYRPWINQILQ 245 ++Y WI ++ Sbjct: 253 TNYLDWIRDNMR 264 >1EKB-B nrPDB Length = 235 Score = 250 bits (638), Expect = 5e-67, Method: Composition-based stats. Identities = 60/238 (25%), Positives = 104/238 (43%), Gaps = 19/238 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA------GRSITVT 75 I+GG++ + + P++ L + CG L+ R+++++AAHC Sbjct: 1 IVGGSDSREGAWPWVVALYF----DDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 76 LGAHNITE-EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LG H + + + + +P YN ++DI ++ L+ K + T + + P + Sbjct: 57 LGLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEE 116 Query: 135 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGNP 192 PPGR+C +AGWG +D LQE + L+ + C +C G Sbjct: 117 NQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYE 176 Query: 193 RKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQIL 244 + +GDSGGPL+C + G+ S+G A P V+ R+ + WI L Sbjct: 177 AGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFL 234 >1FON-A nrPDB Length = 240 Score = 249 bits (637), Expect = 6e-67, Method: Composition-based stats. Identities = 71/242 (29%), Positives = 113/242 (46%), Gaps = 20/242 (8%) Query: 24 GGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLGAHNI 81 G + P+S + L+ CGG LI ++V+TA HC R+ V LG ++ Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 82 TEEEDTWQKLEVI--KQFRHPKYNTSTL--HHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 + E + Q + + F HP +N++ + +DI L+KL A L V P + Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QLCVGNPRK 194 +P C ++GWGR P D LQ+ L +D + CS + + + +C G Sbjct: 121 LPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT- 179 Query: 195 TKSAFKGDSGGPLLC-----AGVAQGIVS----YGRSDAKPPAVFTRISHYRPWINQILQ 245 +S GDSGGPL C + G+ S +G + K P VFTR+S + WI++ + Sbjct: 180 -RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIA 238 Query: 246 AN 247 +N Sbjct: 239 SN 240 >1MZD-A nrPDB Length = 240 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 89/238 (37%), Positives = 126/238 (52%), Gaps = 19/238 (7%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVT 75 EIIGG E PHSRP+MA ++ G CGG LI +VLTAAHC G+S TV Sbjct: 2 EIIGGKEVSPHSRPFMASIQY----GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 57 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 LGAH++++ E + Q LE+ K + + +DIML+KL+ A L V L S+ Sbjct: 58 LGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSK- 116 Query: 136 NFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACS-----HFRDFDHNLQLCV 189 + G C+V GWG T SDTL+EV + ++ + C+ + F +C Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 190 GNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD--AKPPAVFTRIS-HYRPWINQIL 244 G+ + K + KGD+GGPL+C GV IVS G A P ++T ++ Y+ WI L Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >4IGD-A nrPDB Length = 406 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 110/268 (41%), Gaps = 36/268 (13%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 LP+ SR +I G + + P++A L + FCGG L+ ++++TAA Sbjct: 140 LPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHL---NGQPFCGGSLLGSSWIVTAA 196 Query: 66 HC------------------AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTL 107 HC + + LG H ++ Q L V HP+Y+ +T Sbjct: 197 HCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTF 256 Query: 108 HHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKL 167 +D+ L++L E L V + P G M V+GWG+ L+ +TL E+++ Sbjct: 257 ENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEI 313 Query: 168 RLMDPQACSHFR----DFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIV 217 ++D C +C G K A GDSGGP++ G V Sbjct: 314 PIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTV 373 Query: 218 SYGRSDAKP--PAVFTRISHYRPWINQI 243 S+G K V++ I H + WI ++ Sbjct: 374 SWGDDCGKKDRYGVYSYIHHNKDWIQRV 401 >2OCV-B nrPDB Length = 259 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 103/257 (40%), Gaps = 35/257 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 I+ G + + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGWDAEKGIAPWQVML--FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTEND 58 Query: 72 ITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 + V +G H+ T E +K+ + K + HP+YN L DI LLKLK+ + + + Sbjct: 59 LLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC-SHFR 179 P + + + G RV GWG T + + LQ V L +++ C + R Sbjct: 119 CLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTR 178 Query: 180 DFDHNLQLCVGN---PRKTKSAFKGDSGGPLLCA------GVAQGIVSYGRSD--AKPPA 228 + C G K A +GDSGGP + GIVS+G Sbjct: 179 IRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 229 VFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 239 FYTHVFRLKAWIQKVID 255 >1A5I-A nrPDB Length = 265 Score = 247 bits (630), Expect = 4e-66, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 27/248 (10%) Query: 24 GGTECKPHSRPYMAYL--EIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI-----TVTL 76 GG S P+ A + + S+G CGG LI +VLTAAHC S V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEK----ASLTLAVGTLPFP 132 G + + Q +V K H +++ T ++DI LL+LK A + +V + P Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 133 SQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSH---FRDFDHNLQLC 188 +P C ++G+G+ P S+ L+E +RL C+ F N LC Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 189 VGNPRKTK------SAFKGDSGGPLLCAG----VAQGIVSYGRSDAKP--PAVFTRISHY 236 G+ R + A +GDSGGPL+C GI+S+G + P V+T++++Y Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNY 255 Query: 237 RPWINQIL 244 WI + Sbjct: 256 LGWIRDNM 263 >1ETT-H nrPDB Length = 259 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 104/257 (40%), Gaps = 35/257 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSIT--- 73 I+ G + + P+ L + CG LI +VLTAAHC ++ T Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 74 --VTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 V +G H+ T E +K+ + K + HP+YN L DI LLKLK L+ + + Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWGR------TGVLKPGSDTLQEVKLRLMDPQAC-SHFR 179 P + + G RV GWG T V + LQ V L L++ C + R Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR 178 Query: 180 DFDHNLQLCVGNPRK---TKSAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--PPA 228 + C G A +GDSGGP + GIVS+G + Sbjct: 179 IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 229 VFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 239 FYTHVFRLKKWIQKVID 255 >2BDH-A nrPDB Length = 223 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 79/230 (34%), Positives = 118/230 (51%), Gaps = 12/230 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G +C PHS+P+ A L + FC G L+ +VL+AAHC S T+ LG H++ Sbjct: 1 IINGEDCSPHSQPWQAALVME----NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 56 Query: 82 T-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ++E Q +E RHP+YN L +D+ML+KL E S + + ++ SQ Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--A 114 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAF 199 G C V+GWG LQ V + ++ + CS + H C G + K + Sbjct: 115 GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSC 173 Query: 200 KGDSGGPLLCAGVAQGIVSYGRSDAKP---PAVFTRISHYRPWINQILQA 246 GDSGGPL+C G QG+VS+G++ P V+T + + WI + +QA Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >1YC0-A nrPDB Length = 283 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 80/273 (29%), Positives = 120/273 (43%), Gaps = 34/273 (12%) Query: 2 LLLPLPLLLFL---LCSR------AEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCG 52 LL LP C R IIGG+ P S P++A + I S FC Sbjct: 7 LLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS-----FCA 61 Query: 53 GFLIRRNFVLTAAHCAGRS-----ITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTST- 106 G L+ +V++AAHC S ++V LG H D Q + K + Y+ Sbjct: 62 GSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNP 121 Query: 107 LHHDIMLLKLKEK----ASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVL-KPGSDT 161 HD++L++LK+K A+ + V + P + P G C++AGWG S + Sbjct: 122 SDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSS 181 Query: 162 LQEVKLRLMDPQACSHFRDFDHN---LQLCVGNPRKTKSAFKGDSGGPLLCA----GVAQ 214 L+E + L+ CS + + LC G A +GDSGGPL C Sbjct: 182 LREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLY 241 Query: 215 GIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 245 GI+S+G + P V+TR+++Y WIN ++ Sbjct: 242 GIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 274 >3F6U-H nrPDB Length = 240 Score = 242 bits (619), Expect = 8e-65, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 104/241 (43%), Gaps = 21/241 (8%) Query: 23 IGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT--VTLGAHN 80 I G + P+ L + CG LI ++VLTAAHC S V LG ++ Sbjct: 2 IDGKMTRRGDSPWQVVL---LDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD 58 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS----QFN 136 + E L++ + F HP Y+ ST +DI LL L + A+L+ + + P + Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSD-----TLQEVKLRLMDPQACSHF-RDFDHNLQLCVG 190 G+ V GWG + + L +K+ ++ CS + LC G Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAG 178 Query: 191 NPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRPWINQIL 244 + A +GDSGGP++ + G+VS+G V+T++S Y WI+ + Sbjct: 179 ILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHI 238 Query: 245 Q 245 + Sbjct: 239 R 239 >1FIZ-A nrPDB Length = 263 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 107/251 (42%), Gaps = 25/251 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPS--KFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 ++GG +P + P+M L+I + CGG L+ ++VLTAAHC VT Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 80 NITEEE----------DTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTL 129 E Q+ V + H KY + +DI L+K+ +G Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 130 PFPSQFNFVP-PGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFRDFD---HN 184 P P + C V GWG P S TLQE ++ L+D + C+ R ++ + Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 185 LQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRSDAK--PPAVFTRISHY 236 +C G PR +GDSGGPL+C V GI S+G A+ P V+T Y Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 237 RPWINQILQAN 247 WI + +N Sbjct: 241 LNWIASKIGSN 251 >5LHN-A nrPDB Length = 247 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 71/246 (28%), Positives = 110/246 (44%), Gaps = 23/246 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNG--PSKFCGGFLIRRNFVLTAAHCA-----GRSITV 74 I+GG + ++P+ A + G PS CGG LI +V +AAHC + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKY--NTSTLHHDIMLLKLKEK----ASLTLAVGT 128 LG + K EV + H Y ++ H+DI LLK++ A + ++ T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 129 LPFPSQFNFVPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFRDFDHNL-- 185 + P +F P G C + G+G+ L+ ++L+ + C + + Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 186 -QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPAVFTRISHYRP 238 LC +P + KGDSGGPL+C GIVS+GR A P V+TR+SH+ Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLD 240 Query: 239 WINQIL 244 WI + Sbjct: 241 WIQSHI 246 >4Z6A-H nrPDB Length = 249 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 105/240 (43%), Gaps = 19/240 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GG C P+ L + ++ CGG LI +V++AAHC R++ L Sbjct: 1 IVGGKVCPKGECPWQVLLLV----NGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ-- 134 G H+++E + Q V + Y T +HDI LL+L + LT V L P + Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 135 -FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLR-LMDPQACSHFRDFDHNLQLCVGNP 192 + R V+GWG+ + L + + LM + + C G Sbjct: 117 SERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYS 176 Query: 193 RKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKPP--AVFTRISHYRPWINQILQA 246 +K + KGDSGGP GIVS+G+ A V+TR+S Y W+ +++++ Sbjct: 177 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRS 236 >2OQ5-A nrPDB Length = 232 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 66/236 (27%), Positives = 101/236 (42%), Gaps = 23/236 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA-----GRSITVTL 76 I+GGTE + P+ A L+ S CG LI ++++AAHC T + Sbjct: 1 IVGGTEVEEGEWPWQASLQW----DGSHRCGATLINATWLVSAAHCFTTYKNPARWTASF 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G + + K + + H KY + +DI L +L T AV + P Sbjct: 57 G----VTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY 112 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH---FRDFDHNLQLCVGNPR 193 PG + V G+G + L++ ++ L+D C+ + D LC G+ Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLE 172 Query: 194 KTKSAFKGDSGGPLLCA-----GVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQ 242 A +GDSGGPL+ + GIVS+G AK P V+TR++ R WI Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 228 >1Q3X-A nrPDB Length = 328 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 106/267 (39%), Gaps = 34/267 (12%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLT 63 LP+ + L +R G I GG + KP P+ + G L+ N+VLT Sbjct: 69 LPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLT 122 Query: 64 AAHCA------GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKL 116 AAH ++ + +G T E F H Y + + +DI L+KL Sbjct: 123 AAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKL 180 Query: 117 KEKASLTLAVGTLPFP--SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQA 174 K + + + P +F+ + +GWG T + L V + ++D Q Sbjct: 181 NNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQK 239 Query: 175 CS-------HFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIVSYG- 220 C+ + R LC G K + +GDSGG L+ GIVS+G Sbjct: 240 CTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGS 299 Query: 221 --RSDAKPPAVFTRISHYRPWINQILQ 245 +A V+T++ +Y PWI I+ Sbjct: 300 MNCGEAGQYGVYTKVINYIPWIENIIS 326 >1SC8-U nrPDB Length = 262 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 113/254 (44%), Gaps = 25/254 (9%) Query: 14 CSRAEAG---EIIGGTECKPHSRPYMAYLEIVTSNGP-SKFCGGFLIRRNFVLTAAHCA- 68 C + +IIGG ++P+ A + G + CGG LI +V++A HC Sbjct: 5 CGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFI 64 Query: 69 ----GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTL--HHDIMLLKLKEK--- 119 V LG + K EV H Y+ TL H+DI LLK++ K Sbjct: 65 DYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGR 124 Query: 120 -ASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSH 177 A + + T+ PS +N G C + G+G+ + L+ ++L+ + C Sbjct: 125 CAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQ 184 Query: 178 FRDFDHNL---QLCVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDA--KPPA 228 + + LC +P+ + +GDSGGPL+C+ GIVS+GR A P Sbjct: 185 PHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPG 244 Query: 229 VFTRISHYRPWINQ 242 V+TR+SH+ PWI Sbjct: 245 VYTRVSHFLPWIRS 258 >1OP0-A nrPDB Length = 234 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 101/233 (43%), Gaps = 13/233 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 +IGG EC + ++ N FCGG LI +V+TAAHC + LG H+ Sbjct: 1 VIGGNECDINEHRFLVAF----FNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSK 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTST-LHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + Q ++F P N + L DIML+KL + S + + L + Sbjct: 57 KVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPSV 114 Query: 141 GRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVGNPRKTKS 197 G +CR+ GWG T V + D + L+D C LC G + K Sbjct: 115 GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKD 174 Query: 198 AFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C G QGIVSYG P ++T + Y WI + + N Sbjct: 175 TCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >1FIW-A nrPDB Length = 290 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 73/250 (29%), Positives = 107/250 (42%), Gaps = 25/250 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPS--KFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 IIGG + + P+M L+I T + CGG L+ ++LTAAHC VT Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 80 NITEEE----------DTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTL 129 +E Q+ V K H KY+ S+ +DI L+K+ + +G Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 130 PFPSQFNFVPP-GRMCRVAGWGRTGVL-KPGSDTLQEVKLRLMDPQACSHFRDFD---HN 184 P P + C VAGWG + S LQE ++ L+D C+ R ++ + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 185 LQLCVGNPRKTKSAFKGDSGGPLLCAG------VAQGIVSYGRSDAK--PPAVFTRISHY 236 +C G P +GDSGGPL+C V GI S+G A+ P V+T Y Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 237 RPWINQILQA 246 WI + + Sbjct: 241 LNWIASKIGS 250 >1ZJK-A nrPDB Length = 403 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 107/267 (40%), Gaps = 34/267 (12%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLT 63 LP+ + L +R G+I GG + KP P+ + G L+ N+VLT Sbjct: 144 LPVCEPVCGLSARTTGGQIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLT 197 Query: 64 AAHCA------GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKL 116 AAH ++ + +G T E F H Y + + +DI L+KL Sbjct: 198 AAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKL 255 Query: 117 KEKASLTLAVGTLPFP--SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQA 174 K + + + P +F+ + +GWG T + L V + ++D Q Sbjct: 256 NNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQK 314 Query: 175 CS-------HFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIVSYG- 220 C+ + R LC G K + +GDSGG L+ GIVS+G Sbjct: 315 CTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGS 374 Query: 221 --RSDAKPPAVFTRISHYRPWINQILQ 245 +A V+T++ +Y PWI I+ Sbjct: 375 MNCGEAGQYGVYTKVINYIPWIENIIS 401 >2R0L-A nrPDB Length = 248 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 74/244 (30%), Positives = 114/244 (46%), Gaps = 25/244 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS-----ITVTL 76 IIGG+ P S P++A + I S FC G L+ +V++AAHC S ++V L Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTST-LHHDIMLLKLKEK----ASLTLAVGTLPF 131 G H D Q + K + Y+ HD++L++LK+K A+ + V + Sbjct: 56 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 115 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVL-KPGSDTLQEVKLRLMDPQACSHFRDFDHN---LQL 187 P + P G C++AGWG S +L+E + L+ CS + + L Sbjct: 116 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 175 Query: 188 CVGNPRKTKSAFKGDSGGPLLCA----GVAQGIVSYGRSDAK--PPAVFTRISHYRPWIN 241 C G A +GDSGGPL C GI+S+G + P V+TR+++Y WIN Sbjct: 176 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 235 Query: 242 QILQ 245 ++ Sbjct: 236 DRIR 239 >1BQY-A nrPDB Length = 234 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 101/233 (43%), Gaps = 13/233 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 + GG EC + + L N CGG LI +++V+TAAHC + + G H+ Sbjct: 1 VFGGDECNINEHRSLVVL----FNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSK 56 Query: 82 T-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 ED + K F + + DIML+KL S + + L + Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPSV 114 Query: 141 GRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPRKTKS 197 G +CR+ GWG+T K D + ++D C + N LC G + + Sbjct: 115 GSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRD 174 Query: 198 AFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 DSGGPL+C G+ QGIVS+G P V+T++ Y WI I+ N Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >4XDE-A nrPDB Length = 257 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 105/244 (43%), Gaps = 28/244 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 ++GG + PY+A L FC G LI +VLTAAHC +TV L Sbjct: 3 VVGGLVALRGAHPYIAALYW-----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKAS-----LTLAVGTLPF 131 G + Q L V H ++ + HD+ LL+L+E A L+ V + Sbjct: 58 GQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSL 117 Query: 132 PSQFNFVPPGRMCRVAGWGRTGVL-KPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QL 187 PS +C+VAGWG + + LQE ++ + + CS ++ L Sbjct: 118 PSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGML 177 Query: 188 CVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDA--KPPAVFTRISHYRP 238 C G A +GDSGGPL+C QGI+S+G P V+T +++Y Sbjct: 178 CAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLA 237 Query: 239 WINQ 242 WI + Sbjct: 238 WIRE 241 >3S69-A nrPDB Length = 234 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 71/233 (30%), Positives = 98/233 (42%), Gaps = 13/233 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 +IGG EC + + N FC G LI +VLTAAHC + + LG H+ Sbjct: 1 VIGGDECNINEHRSLVAF----FNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSK 56 Query: 82 TEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + Q ++F P N L DIML+KL + S + + +P + Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPPSV 114 Query: 141 GRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVGNPRKTKS 197 G +C + GWG +K D + L+D C LC G K Sbjct: 115 GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKD 174 Query: 198 AFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 GDSGGPL+C G QGIVS+G P V+T++ Y WI I+ N Sbjct: 175 TCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >5TO3-B nrPDB Length = 409 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 104/257 (40%), Gaps = 35/257 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 72 ITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + + Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWGRTGV------LKPGSDTLQEVKLRLMDPQACSHF-R 179 P + + + G RV GWG K LQ V L +++ C R Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTR 178 Query: 180 DFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA------GVAQGIVSYGRSDAK--PPA 228 + C G P + K A +GDSGGP + GIVS G + Sbjct: 179 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYG 238 Query: 229 VFTRISHYRPWINQILQ 245 +T + + WI +++ Sbjct: 239 FYTHVFRLKKWIQKVID 255 >2XXL-A nrPDB Length = 408 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 78/268 (29%), Positives = 103/268 (38%), Gaps = 35/268 (13%) Query: 13 LCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA---- 68 C + + G E K SRP+MA L CGG +I ++LTAAHC Sbjct: 110 DCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQ 169 Query: 69 GRSITVTLGAHNITEEEDTWQK------------LEVIKQFRHPKYNTSTLHHDIMLLKL 116 + LG H I+ EED Q+ + + K H KY+ + HDI LLKL Sbjct: 170 NDLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKL 229 Query: 117 KEKASLTLAVGTLPFPSQFNFVPPG---RMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 + + P V GWG T SD L + + L Sbjct: 230 NRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRS 288 Query: 174 ACSH-FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG----------VAQGIVSYG-- 220 ACS +R QLCVG + + KGDSGGPL V GIVS G Sbjct: 289 ACSQAYRRAVPLSQLCVGGGD-LQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVV 347 Query: 221 -RSDAKPPAVFTRISHYRPWINQILQAN 247 P ++T + Y WI + +N Sbjct: 348 TCGQISLPGLYTNVGEYVQWITDTMASN 375 >4DJZ-B nrPDB Length = 251 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 36/252 (14%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-------------- 67 I G + + P++A L + FCGG L+ ++++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHL---NGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 68 ----AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLT 123 + + LG H ++ Q L V HP+Y+ +T +D+ L++L E L Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 117 Query: 124 LAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR---- 179 V + P G M V+GWG+ L+ +TL E+++ ++D C Sbjct: 118 AFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAPLK 174 Query: 180 DFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIVSYGRSDAKP--PAVFT 231 +C G K A GDSGGP++ G VS+G K V++ Sbjct: 175 KKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYS 234 Query: 232 RISHYRPWINQI 243 I H + WI ++ Sbjct: 235 YIHHNKDWIQRV 246 >1AZZ-A nrPDB Length = 226 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 76/226 (33%), Positives = 113/226 (50%), Gaps = 13/226 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS--ITVTLGAH 79 I+GG E P+S P+ A L I FCGG LI ++LTAAHC + + V LGAH Sbjct: 1 IVGGVEAVPNSWPHQAALFI----DDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NI E+E T ++ H YN+ + +DI +++L +LT A+ T+ PS V Sbjct: 57 NIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPS--TDVG 114 Query: 140 PGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSA 198 G + GWG + SD L++V + +M C + +C+ + K Sbjct: 115 VGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICI-DSTGGKGT 173 Query: 199 FKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWIN 241 GDSGGPL G+ GI S+G + +A P FTR++++ WI Sbjct: 174 CNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >4Q7Y-A nrPDB Length = 250 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 87/234 (37%), Positives = 116/234 (49%), Gaps = 14/234 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSIT----VTLG 77 IIGG E PHSRPYMA + G CGGFL+R +V++AAHC V LG Sbjct: 1 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AH ++ E T Q + HP Y+ T +DI LL+L A L AVG L P + Sbjct: 57 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRAR 116 Query: 138 VP-PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCV-GNPRK 194 P G CRVAGWG + L E K+R++DP C S ++ LC Sbjct: 117 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 176 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQ 245 + DSGGPL+C A G+VS+ D K P V+T++S + WI +++ Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 230 >5LPF-A nrPDB Length = 234 Score = 229 bits (584), Expect = 9e-61, Method: Composition-based stats. Identities = 74/236 (31%), Positives = 114/236 (48%), Gaps = 21/236 (8%) Query: 25 GTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEE 84 G+ C S+P+ L NG S C G L+ +++VLTAAHC + + +G ++ Sbjct: 7 GSPCARGSQPWQVSL----FNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLL 62 Query: 85 EDTWQKLEVIKQFRHPKYN--------TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 + Q + HPKY+ T HD+MLLKL L V L P + Sbjct: 63 QG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYR-- 119 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDT-LQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRK 194 PG C+VAGWG T + + L + ++ P+ C + N +C G + Sbjct: 120 CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDR 178 Query: 195 TKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQAN 247 + + DSGGPL+C QGI+S+G A+ PAV+T+I Y WIN+++++N Sbjct: 179 GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >2OLG-A nrPDB Length = 278 Score = 228 bits (582), Expect = 1e-60, Method: Composition-based stats. Identities = 73/273 (26%), Positives = 116/273 (42%), Gaps = 36/273 (13%) Query: 7 PLLLFLLCS-RAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKF-CGGFLIRRNFVLTA 64 P LL C + EA +I+ G + P P+ A + S+ +F CGG LI +++TA Sbjct: 7 PELLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTA 66 Query: 65 AHCAGRSI--------TVTLGAHNITEEEDTWQKLEV-----------IKQFRHPKYNTS 105 AHC + V LG N + D + + V + +HP Y Sbjct: 67 AHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDG 126 Query: 106 TLH--HDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQ 163 + HDI L++L + T + + P V G+ V GWGRT S Q Sbjct: 127 SKDRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTET-GQYSTIKQ 185 Query: 164 EVKLRLMDPQACSH----FRDFDHNLQLCVGNPRKTKSAFKGDSGGPL-----LCAGVAQ 214 ++ + ++ + C+ + QLC G K K + GDSGGPL + Sbjct: 186 KLAVPVVHAEQCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLE 244 Query: 215 GIVSYGRSDAKP--PAVFTRISHYRPWINQILQ 245 G+VS+G + P ++T++ YR WI ++ Sbjct: 245 GLVSFGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >4KKD-A nrPDB Length = 433 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 70/288 (24%), Positives = 111/288 (38%), Gaps = 48/288 (16%) Query: 4 LPLPLLLFLLCSRAEA---GEIIGGTECKPHSRPYMAYLEIVTSN---GPSKFCGGFLIR 57 LP L SR+ IIGG +P P+ A + + ++ F G L+ Sbjct: 134 LPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLS 193 Query: 58 RNFVLTAAHC-------------AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNT 104 +++LTAAH + +TV LG H++ ++ + HP +N Sbjct: 194 ASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNI 252 Query: 105 STLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP-PGRMCRVAGWGRTGVL-------- 155 +HDI L++L+E L V + P P P + VAGWG + Sbjct: 253 QNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIIS 312 Query: 156 ---KPGSDTLQEVKLRLMDPQACSHFRD------FDHNLQLCVGNPRKTKSAFKGDSGGP 206 + SD LQ VKL ++ C + C G K GDSG Sbjct: 313 SGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEA 372 Query: 207 LL------CAGVAQGIVSYG----RSDAKPPAVFTRISHYRPWINQIL 244 + V QG+VS+G + V+T++S+Y W+ + + Sbjct: 373 FVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >1GPZ-A nrPDB Length = 399 Score = 226 bits (576), Expect = 8e-60, Method: Composition-based stats. Identities = 67/265 (25%), Positives = 113/265 (42%), Gaps = 33/265 (12%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 LP+ + + +IIGG + K + P+ + I GG L+ ++LTAA Sbjct: 142 LPVCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAA 195 Query: 66 HC---------AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTS---TLHHDIML 113 H + S+ V LG N+ E + + HP Y DI L Sbjct: 196 HTLYPKEHEAQSNASLDVFLGHTNVEEL-MKLGNHPIRRVSVHPDYRQDESYNFEGDIAL 254 Query: 114 LKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 L+L+ +L + + P F G M V+G+G + + L+ V+L + +PQ Sbjct: 255 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVME--EKIAHDLRFVRLPVANPQ 312 Query: 174 ACSHFRDFDHNL------QLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGR 221 AC ++ + + C G+P + A +GDSGG P VA GIVS+G Sbjct: 313 ACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI 372 Query: 222 SDAKPPAVFTRISHYRPWINQILQA 246 ++ +T++ +Y WI + ++ Sbjct: 373 GCSRGYGFYTKVLNYVDWIKKEMEE 397 >2ZKS-A nrPDB Length = 240 Score = 226 bits (576), Expect = 9e-60, Method: Composition-based stats. Identities = 77/234 (32%), Positives = 117/234 (50%), Gaps = 19/234 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS---ITVTLGA 78 IIGG E PHSRPYMA L+ S CGG L+ +VLTAAHC + + + LG Sbjct: 1 IIGGREVIPHSRPYMASLQ----RNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNT-STLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 H + T + +HP+Y L +D+ LL+L K + + L PS+ Sbjct: 57 HTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQV 113 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN---LQLCVGNPRK 194 V G C +AGWG T S L+E+ L+++D + C++ R ++ + +C+ K Sbjct: 114 VAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 173 Query: 195 TKSAFKGDSGGPLLCAG--VAQGIVSYGRSDAK---PPAVFTRISHYRPWINQI 243 ++ KGDSGGPL+C V G++S+ P V T ++ Y WI ++ Sbjct: 174 DQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 227 >1MD7-A nrPDB Length = 328 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 112/264 (42%), Gaps = 33/264 (12%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 LP+ + + IIGG + K + P+ + I GG L+ ++LTAA Sbjct: 74 LPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAA 127 Query: 66 HC---------AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTS---TLHHDIML 113 H + S+ V LG N+ E + + HP Y DI L Sbjct: 128 HTLYPKEHEAQSNASLDVFLGHTNVEEL-MKLGNHPIRRVSVHPDYRQDESYNFEGDIAL 186 Query: 114 LKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 L+L+ +L + + P F G M V+G+G + + L+ V+L + +PQ Sbjct: 187 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVME--EKIAHDLRFVRLPVANPQ 244 Query: 174 ACSHFRDFDHNL------QLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGR 221 AC ++ + + C G+P + A +GD+GG P VA GIVS+G Sbjct: 245 ACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI 304 Query: 222 SDAKPPAVFTRISHYRPWINQILQ 245 ++ +T++ +Y WI + ++ Sbjct: 305 GCSRGYGFYTKVLNYVDWIKKEME 328 >5XRF-A nrPDB Length = 242 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 66/238 (27%), Positives = 102/238 (42%), Gaps = 11/238 (4%) Query: 16 RAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVT 75 + + +IGG EC + ++A TS + C G LI +VL AAHC R + + Sbjct: 1 QKSSELVIGGNECDTNEHRFLAA--FFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIY 58 Query: 76 LGAHNITEEEDTWQKLE-VIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LG HN + + D Q+ + + + + D++LLKL + S + + L Sbjct: 59 LGMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LP 116 Query: 135 FNFVPPGRMCRVAGWGR-TGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ--LCVGN 191 + G +CRV GWG + D + L++ C LC G Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 192 PRKTKSAFKGDSGGPLLCAGVAQGIVSYG---RSDAKPPAVFTRISHYRPWINQILQA 246 DSGGPL+C G QGIV +G + P ++TR+S+Y WI I+ Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAG 234 >1AE5-A nrPDB Length = 225 Score = 223 bits (569), Expect = 5e-59, Method: Composition-based stats. Identities = 71/230 (30%), Positives = 107/230 (46%), Gaps = 16/230 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI----TVTLG 77 I+GG + +P P++A ++ N FCGG LI FV+TAA C TV LG Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 A+++ E ++ I Y+ +D+MLL+L +A+LT +V LP P Q Sbjct: 57 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKS 197 V G C+VAGWG S + V + + C +C G + Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------RPNNVCTGVLTRRGG 169 Query: 198 AFKGDSGGPLLCAGVAQGIVSYGRS-DAKPPAVFTRISHYRPWINQILQA 246 GD G PL+C G+A G+ S+ + P FTR++ +R WI+ +L Sbjct: 170 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 219 >4IW4-E nrPDB Length = 279 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 45/267 (16%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSN---GPSKFCGGFLIRRNFVLTAAHC----------- 67 IIGG +P P+ A + + ++ F G L+ +++LTAAH Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 68 --AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125 + +TV LG H++ ++ + HP +N +HDI L++L+E L Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 126 VGTLPFPSQFNFVP-PGRMCRVAGWGRTGVL-----------KPGSDTLQEVKLRLMDPQ 173 V + P P P + VAGWG + + SD LQ VKL ++ Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 174 ACSHFRD------FDHNLQLCVGNPRKTKSAFKGDSGGPLL------CAGVAQGIVSYG- 220 C + C G K GDSGG + V QG+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 221 ---RSDAKPPAVFTRISHYRPWINQIL 244 + V+T++S+Y W+ + + Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >1EQ9-A nrPDB Length = 222 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 15/231 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG-----RSITVTL 76 I+GG + PY L + S CG ++ N VLTAAHC + V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 77 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 G + ++E D +V + Y+ L +D+ L+ L V + + Sbjct: 57 GTNYLSESGD---VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDE 113 Query: 137 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTK 196 + C + GWG T + + LQE++L + + C + + +C ++ + Sbjct: 114 DLESN-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICT-LTKRGE 171 Query: 197 SAFKGDSGGPLLCAGVAQGIVSYGRSDA-KPPAVFTRISHYRPWINQILQA 246 A GDSGGPL+ G GIVS+G A P V+TR+S + WIN L+ Sbjct: 172 GACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >2QY0-B nrPDB Length = 242 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 107/249 (42%), Gaps = 33/249 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC---------AGRSI 72 IIGG + K + P+ + I GG L+ ++LTAAH + S+ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 73 TVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTS---TLHHDIMLLKLKEKASLTLAVGTL 129 V LG N+ E + + HP Y DI LL+L+ +L + + Sbjct: 55 DVFLGHTNVEEL-MKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 113 Query: 130 PFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---- 185 P F G M V+G+G + + L+ V+L + +PQAC ++ + + Sbjct: 114 CLPDNDTFYDLGLMGYVSGFGVME--EKIAHDLRFVRLPVANPQACENWLRGKNRMDVFS 171 Query: 186 --QLCVGNPRKTKSAFKGDSGG------PLLCAGVAQGIVSYGRSDAKPPAVFTRISHYR 237 C G+P + A +GDSGG P VA GIVS+G ++ +T++ +Y Sbjct: 172 QNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYV 231 Query: 238 PWINQILQA 246 WI + ++ Sbjct: 232 DWIKKEMEE 240 >4FXG-H nrPDB Length = 242 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 61/249 (24%), Positives = 98/249 (39%), Gaps = 34/249 (13%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA------GRSITVT 75 I GG + KP P+ + G L+ N+VLTAAH ++ + Sbjct: 1 IYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 54 Query: 76 LGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIMLLKLKEKASLTLAVGTLPFP-- 132 +G T E F H Y + + +DI L+KL K + + + P Sbjct: 55 MGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRK 112 Query: 133 SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-------HFRDFDHNL 185 +F+ + +GWG T + L V + ++D Q C+ + R Sbjct: 113 EAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTAN 171 Query: 186 QLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIVSYG---RSDAKPPAVFTRISHY 236 LC G K + +GD+GG L+ GIVS+G +A V+T++ +Y Sbjct: 172 MLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINY 231 Query: 237 RPWINQILQ 245 PWI I+ Sbjct: 232 IPWIENIIS 240 >4BXW-A nrPDB Length = 423 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 65/245 (26%), Positives = 107/245 (43%), Gaps = 23/245 (9%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGA 78 I+ G +CK P+ A L FCGG ++ +VLTAAHC +I+V +G Sbjct: 169 RIVNGMDCKLGECPWQAAL---VDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGE 225 Query: 79 HNITEEED----TWQKLEVIKQFRHP----KYNTSTLHHDIMLLKLKEKASLTLAVGTLP 130 + + E + K+ V K+F P K++ + +DI ++++K + V Sbjct: 226 IDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPAC 285 Query: 131 FPSQF---NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN-LQ 186 P+ + V+G+GR P S TL+ +K+ +D C + Sbjct: 286 LPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNM 345 Query: 187 LCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAK--PPAVFTRISHYRPWI 240 C G + A +GDSGGP GIVS G A+ +T++S + PWI Sbjct: 346 FCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPWI 405 Query: 241 NQILQ 245 +I++ Sbjct: 406 KRIMR 410 >1YM0-A nrPDB Length = 238 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 60/241 (24%), Positives = 103/241 (42%), Gaps = 18/241 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS----ITVTLG 77 I+GG E +P+ P+ + + S FCGG +I +V+ AAHC +++ +G Sbjct: 1 IVGGIEARPYEFPWQVS--VRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 H+ + Q +V F + Y+ +TL +D+ ++K + + VG + P N Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 138 VPPGRMCRVAGWGRTGVLKP-GSDTLQEVKLRLMDPQACSHFR--DFDHNLQLCVGNPRK 194 R + +GWG L+ V L + C D ++ +C + Sbjct: 119 Y-VYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTG 177 Query: 195 --TKSAFKGDSGGPLLCAG-----VAQGIVSYGRSDAKP-PAVFTRISHYRPWINQILQA 246 + + +GDSGGPL GIVS+G A P V++R+ + WI + Sbjct: 178 MTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTITN 237 Query: 247 N 247 N Sbjct: 238 N 238 >1ELV-A nrPDB Length = 333 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 61/271 (22%), Positives = 106/271 (39%), Gaps = 39/271 (14%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 +P+ E IIGG++ + P+ + + + GG LI +VLTAA Sbjct: 67 VPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFF-------DNPWAGGALINEYWVLTAA 119 Query: 66 HCA--GRSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-------TSTLHHDIMLLK 115 H R T+ +G+ ++ K+ F HP + + +DI L++ Sbjct: 120 HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVR 179 Query: 116 LKEKASLTLAVGTLPFP--SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 LK+ + V + P S + G + ++GWGRT + L+ +L + + Sbjct: 180 LKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLR 238 Query: 174 ACSHFRD----------FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGI 216 C + +C G + + KGDSGG A G+ Sbjct: 239 KCKEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDKTKFYAAGL 297 Query: 217 VSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 VS+G ++TR+ +Y WI + +Q N Sbjct: 298 VSWGPQCGT-YGLYTRVKNYVDWIMKTMQEN 327 >5KWM-A nrPDB Length = 230 Score = 213 bits (542), Expect = 6e-56, Method: Composition-based stats. Identities = 56/225 (24%), Positives = 90/225 (40%), Gaps = 17/225 (7%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA----GRSITVTLG 77 I+GG + P+ L + +FCGG L N V+TAAHC I V G Sbjct: 1 IVGGEDANVQDHPFTVAL---VTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 ++ E T K V + HP+Y + D+ +L L+ + + Sbjct: 58 RTVMSSNEGTVSK--VTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDA 111 Query: 138 -VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKT 195 P + GWG T +D LQ+ + + C + ++ + +C G P Sbjct: 112 GYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGG 171 Query: 196 KSAFKGDSGGPLLCAGVAQGIVSYGRSDAK--PPAVFTRISHYRP 238 +GDSGGP++ G+ S+G A+ P V+ R+ Y Sbjct: 172 VDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGKPGVYARVGAYYD 216 >2XRC-A nrPDB Length = 565 Score = 211 bits (537), Expect = 2e-55, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 106/256 (41%), Gaps = 25/256 (9%) Query: 3 LLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVL 62 LLP I+GG + P+ + + CGG I ++L Sbjct: 303 LLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI----KDASGITCGGIYIGGCWIL 358 Query: 63 TAAHCAGRSITVT--LGAHNITEEEDTWQKL---EVIKQFRHPKYNTSTLHHDIMLLKLK 117 TAAHC S T + + +++ V + H YN T +DI L+++K Sbjct: 359 TAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMK 418 Query: 118 EKASLTLAVGTLPFPSQFNFVP----PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 + + P+ + P P C V+GWGR + +LQ +++L+ Sbjct: 419 KDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN- 476 Query: 174 ACSHFRD--FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-----VAQGIVSYGRSDAKP 226 CS F F C G + A KGDSGGPL+C G+VS+G + KP Sbjct: 477 -CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKP 535 Query: 227 --PAVFTRISHYRPWI 240 P V+T++++Y WI Sbjct: 536 EFPGVYTKVANYFDWI 551 >5UBM-A nrPDB Length = 252 Score = 211 bits (537), Expect = 2e-55, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 102/256 (39%), Gaps = 39/256 (15%) Query: 21 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGA 78 IIGG++ + P+ + + + GG LI +VLTAAH R T+ +G+ Sbjct: 1 RIIGGSDADIKNFPWQVFF-------DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGS 53 Query: 79 HNITEEEDTWQKLEV-IKQFRHPKYN-------TSTLHHDIMLLKLKEKASLTLAVGTLP 130 ++ K+ F HP + + +DI L++LK+ + V + Sbjct: 54 TSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 131 FP--SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD-------- 180 P S + G + ++GWGRT + L+ +L + + C + Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAE 172 Query: 181 --FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDAKPPAVFT 231 +C G + + KGDSGG A G+VS+G ++T Sbjct: 173 AYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYT 230 Query: 232 RISHYRPWINQILQAN 247 R+ +Y WI + +Q N Sbjct: 231 RVKNYVDWIMKTMQEN 246 >1PPF-E nrPDB Length = 218 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 20/231 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVT----LG 77 I+GG +PH+ P+M L++ FCG LI NFV++AAHC LG Sbjct: 1 IVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 AHN++ E T Q V + F Y+ L +DI++L+L A++ V P+Q Sbjct: 57 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 115 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKS 197 + G C GWG G + + LQE+ + ++ C +C + Sbjct: 116 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR-------SNVCTLVRGRQAG 167 Query: 198 AFKGDSGGPLLCAGVAQGIVSY---GRSDAKPPAVFTRISHYRPWINQILQ 245 GDSG PL+C G+ GI S+ G + P F ++ + WI+ I+Q Sbjct: 168 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >4J1Y-A nrPDB Length = 397 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 60/271 (22%), Positives = 105/271 (38%), Gaps = 39/271 (14%) Query: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65 +P+ E IGG++ + P+ + + + GG LI +VLTAA Sbjct: 131 VPVCGVPREPFEEKARAIGGSDADIKNFPWQVFF-------DNPWAGGALINEYWVLTAA 183 Query: 66 HCA--GRSITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-------TSTLHHDIMLLK 115 H R T+ +G+ ++ K+ F HP + + +DI L++ Sbjct: 184 HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVR 243 Query: 116 LKEKASLTLAVGTLPFP--SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173 LK+ + V + P S + G + ++GWGRT + L+ +L + + Sbjct: 244 LKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLR 302 Query: 174 ACSHFRD----------FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGI 216 C + +C G + + KGDSGG A G+ Sbjct: 303 KCKEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDKTKFYAAGL 361 Query: 217 VSYGRSDAKPPAVFTRISHYRPWINQILQAN 247 VS+G ++TR+ +Y WI + +Q N Sbjct: 362 VSWGPQCGT-YGLYTRVKNYVDWIMKTMQEN 391 >5O32-I nrPDB Length = 244 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 65/237 (27%), Positives = 103/237 (43%), Gaps = 25/237 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVT--LGAH 79 I+GG + P+ + + CGG I ++LTAAHC S T + Sbjct: 1 IVGGKRAQLGDLPWQVAI----KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 56 Query: 80 NITEEEDTWQKL---EVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 136 + +++ V + H YN T +DI L+++K+ + P+ Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 116 Query: 137 FVP----PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVG 190 + P P C V+GWGR + +LQ +++L+ CS F F C G Sbjct: 117 WSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 173 Query: 191 NPRKTKSAFKGDSGGPLLCAG-----VAQGIVSYGRSDAKP--PAVFTRISHYRPWI 240 + A KGDSGGPL+C G+VS+G + KP P V+T++++Y WI Sbjct: 174 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 230 >2B9L-A nrPDB Length = 394 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 62/252 (24%), Positives = 102/252 (40%), Gaps = 33/252 (13%) Query: 26 TECKPHSRPYMAYLE----IVTSNGPSKFCGGFLIRRNFVLTAAHCAGR------SITVT 75 E + P+M + I S CGG LI + VLT AHC +I + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 76 LGAHNITEEED--TWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 G + E++ +Q+ ++ + H +N T+ +D+ LL L +GT+ P Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 134 QFNFVPPGRMCRVAGWGRTGVLK--PGSDTLQEVKLRLMDPQACSH--------FRDFDH 183 Q C +GWG+ S+ L++++L +D C + Sbjct: 255 QSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCAG-------VAQGIVSYGRSDA--KPPAVFTRIS 234 +C G + K GD G PL C + GIV++G P V+ ++ Sbjct: 314 QTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVA 372 Query: 235 HYRPWINQILQA 246 H+R WI+Q +QA Sbjct: 373 HFRNWIDQEMQA 384 >2HLC-A nrPDB Length = 230 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 61/230 (26%), Positives = 99/230 (43%), Gaps = 15/230 (6%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 II G E PY A L+I + +CGG LI ++LTAAHC +++V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS--QFNFVP 139 + E + + H +N T +D+ L+K+ T + + PS + N Sbjct: 61 VQYEG-EAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELNNKF 118 Query: 140 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSH--FRDFDHNLQLCVGNPRKTKS 197 V+GWG++ LQ ++D C+ +C G+ KS Sbjct: 119 ENIWATVSGWGQSNTDTV---ILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 198 AFKGDSGGPLLCAG--VAQGIVSY--GRSD-AKPPAVFTRISHYRPWINQ 242 GDSGGP + + + G+VS+ G + P F+R++ Y WI Q Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >6BQM-A nrPDB Length = 506 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 67/247 (27%), Positives = 106/247 (42%), Gaps = 29/247 (11%) Query: 19 AGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI----TV 74 + IIGG + PYM L N FCGG + +VLTAAHC + V Sbjct: 8 SSRIIGGEQATAGEWPYMVAL--TARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDV 65 Query: 75 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 134 LGA ++ + +T +++ V + + H Y T+++ +DI +L+L+ L + S Sbjct: 66 LLGAFDMN-DVNTAERIHVRQIYVHNSYITASMGNDIAVLELERD-PLPRRSVQISDSSD 123 Query: 135 FNFVPPGRMCRVAGWG-RTGVLKPGSD---TLQEVKLRLMDPQAC---------SHFRDF 181 FN + V G+G R V SD L +V++ + C + Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 182 DHNLQLCVGNPRKTKSAFKGDSGGPLLCAGV----AQGIVSYGRSD--AKPPAVFTRISH 235 N C G+ K A GD+GGP+ G+VS+G A P V+T +S Sbjct: 184 LTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSV 241 Query: 236 YRPWINQ 242 + W++ Sbjct: 242 FNDWLDD 248 >3I77-A nrPDB Length = 230 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 97/233 (41%), Gaps = 24/233 (10%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA---GRSITVTLGA 78 ++GGT P+M L + G FCGG L ++ VLTAAHC G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG---FCGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P + T D L+KL + + TL + T +Q F Sbjct: 58 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 117 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPR-K 194 VAGWG L + + + AC F N +C G P Sbjct: 118 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 195 TKSAFKGDSGGPLLCA-----GVAQGIVSYGRSDAKP--PAVFTRISHYRPWI 240 +GDSGGP+ + GIVS+G A+P P V+T +S + I Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAI 223 >2ASU-B nrPDB Length = 234 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 68/239 (28%), Positives = 106/239 (44%), Gaps = 28/239 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGR------SITVT 75 ++GG P + P+ L + FCGG L++ ++LTA C V Sbjct: 1 VVGGH---PGNSPWTVSLR---NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 76 LG--AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 LG N E + Q++ V K P + ++LLKL+ +L V + P Sbjct: 55 LGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ------LVLLKLERSVTLNQRVALICLPP 108 Query: 134 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNP 192 ++ VPPG C +AGWG T L L ++ Q C+ R ++C Sbjct: 109 EWYVVPPGTKCEIAGWGETKGTG-NDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGL 167 Query: 193 RKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQ 245 A +GD GGPL C + V +GI+ R A+ PAVFTR+S + WI+++++ Sbjct: 168 LAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >4LK4-A nrPDB Length = 357 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 70/246 (28%), Positives = 111/246 (45%), Gaps = 22/246 (8%) Query: 14 CSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNG-PSKFCGGFLIRRNFVLTAAHCAGR-- 70 + + II G+ P + L ++ +FCGG + +VLTAAHC Sbjct: 3 STADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRS 62 Query: 71 --SITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGT 128 S+ V +GA+++ ++ K +RH Y+ S L +DI +++L + +SL T Sbjct: 63 AASVDVIIGAYDLNNSSQGE-RIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPA--IT 119 Query: 129 LPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDT--LQEVKLRLMDPQACSHFRDFD---- 182 L P+ +P VAGWG T KP T LQEV + L+ C Sbjct: 120 LAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSD 179 Query: 183 -HNLQLCVGNPRKTKSAFKGDSGGPLLCA-GVAQ-GIVSYGRSDAKP---PAVFTRISHY 236 ++ C K + +GD+GGP++ G Q GIVS+G V+T +S++ Sbjct: 180 PNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYF 237 Query: 237 RPWINQ 242 R WI + Sbjct: 238 RDWITK 243 >3BEU-A nrPDB Length = 224 Score = 196 bits (498), Expect = 8e-51, Method: Composition-based stats. Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 28/232 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA---GRSITVTLGA 78 ++GGT P+M L S CGG L ++ VLTAAHC G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P + T D L+KL + + TL + T +Q F Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF 112 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPRKT 195 VAGWG L + + + AC F N +C G K Sbjct: 113 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQ 165 Query: 196 KSAFKGDSGGPLLCA-----GVAQGIVSYGRSDAK--PPAVFTRISHYRPWI 240 + +GDSGGP+ V GIVS+G A+ V+T +S + I Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAI 217 >1PQ7-A nrPDB Length = 224 Score = 193 bits (490), Expect = 7e-50, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 19/230 (8%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTLG 77 I+GGT P++ + S +CGG L+ N VLTAAHC + G Sbjct: 1 IVGGTSASAGDFPFIVSI----SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNF 137 + + T T V HP Y+ + +D+ +LKL +G + + Sbjct: 57 SLSRTSGGITSSLSSVR---VHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDT-LQEVKLRLMDPQACSHFRDF--DHNLQLCVGNPRK 194 G VAGWG T + L +V + ++ C N C G Sbjct: 112 PVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSG 171 Query: 195 TKSAFKGDSGGPLL-CAGVAQGIVSYGRSDAKPP--AVFTRISHYRPWIN 241 K + +GDSGGP++ + G VS+G A+P V+ + R +I+ Sbjct: 172 GKDSCQGDSGGPIVDSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >4F4O-C nrPDB Length = 347 Score = 191 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 61/281 (21%), Positives = 102/281 (36%), Gaps = 53/281 (18%) Query: 4 LPLPLLLFLLCSRA--EAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFV 61 LP + + I+GG+ S P+ A + + G LI ++ Sbjct: 83 LPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTS----GATLINEQWL 138 Query: 62 LTAAHCAGRSITVTLGAHN----------ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDI 111 LT A + LG N + Q++E+ K HP +T DI Sbjct: 139 LTTA------KNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV----DI 188 Query: 112 MLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMD 171 L+KLK+K + V + PS+ ++V G + V+GWGR L ++ L+ V L + D Sbjct: 189 GLIKLKQKVPVNERVMPICLPSK-DYVNVGLVGYVSGWGRNANLN-FTEHLKYVMLPVAD 246 Query: 172 PQACSHFR------------------DFDHNLQLCVGNPRKTKSAFKGDSGGPLLC---- 209 + C + + C G + + GD+G Sbjct: 247 QEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKD 306 Query: 210 --AGVAQGIVSYGRSD-AKPPAVFTRISHYRPWINQILQAN 247 A GI+S+ +S V+ R++ WI + N Sbjct: 307 DDTWYAAGILSFDKSCRTAEYGVYVRVTSILDWIQTTIADN 347 >4WJG-C nrPDB Length = 315 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 63/277 (22%), Positives = 102/277 (36%), Gaps = 45/277 (16%) Query: 4 LPLPLLLFLLCSRAEA--GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFV 61 LP + I+GG S P+ A + + G LI ++ Sbjct: 51 LPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTT----GATLINEQWL 106 Query: 62 LTAA------HCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLK 115 LT A H + T A +T Q +E+ K HP Y+ DI L+K Sbjct: 107 LTTAKNLFLNH--SENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIK 160 Query: 116 LKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC 175 LK+K S+ V + PS+ ++ GR+ V+GWGR K +D L+ V L + D C Sbjct: 161 LKQKVSVNERVMPICLPSK-DYAEVGRVGYVSGWGRNANFK-FTDHLKYVMLPVADQDQC 218 Query: 176 SHFR------------------DFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AG 211 + C G + + GD+G Sbjct: 219 IRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTW 278 Query: 212 VAQGIVSYGRSDA-KPPAVFTRISHYRPWINQILQAN 247 A GI+S+ +S A V+ +++ + W+ + + N Sbjct: 279 YATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 315 >2FMJ-A nrPDB Length = 222 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 61/232 (26%), Positives = 92/232 (39%), Gaps = 30/232 (12%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA---GRSITVTLGA 78 ++GGT P+M L S CGG L ++ VLTAAHC G + ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 79 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNF 137 + + + K+ K + P YN D L+KL + + TL + T +Q F Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPINQPTLKIATTTAYNQGTF 110 Query: 138 VPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVGNPRKT 195 VAGWG L + + + AC N ++C G Sbjct: 111 -------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 196 KSAFKGDSGGPLLCA-----GVAQGIVSYGRSDAK--PPAVFTRISHYRPWI 240 +GDSGGP+ + GIVS+G A+ V+T +S + I Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAI 215 >4X0L-C nrPDB Length = 259 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 61/271 (22%), Positives = 100/271 (36%), Gaps = 43/271 (15%) Query: 8 LLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA-- 65 + I+GG S P+ A + + G LI ++LT A Sbjct: 1 VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTT----GATLINEQWLLTTAKN 56 Query: 66 ----HCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKAS 121 H + T A +T Q +E+ K HP Y+ DI L+KLK+K S Sbjct: 57 LFLNH--SENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVS 110 Query: 122 LTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR-- 179 + V + PS+ ++ GR+ V+GWGR K +D L+ V L + D C Sbjct: 111 VNERVMPICLPSK-DYAEVGRVGYVSGWGRNANFK-FTDHLKYVMLPVADQDQCIRHYEG 168 Query: 180 ----------------DFDHNLQLCVGNPRKTKSAFKGDSGGPLLC------AGVAQGIV 217 + C G + + GD+G A GI+ Sbjct: 169 STVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGIL 228 Query: 218 SYGRSDA-KPPAVFTRISHYRPWINQILQAN 247 S+ +S A V+ +++ + W+ + + N Sbjct: 229 SFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 259 >1SI5-H nrPDB Length = 240 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 64/240 (26%), Positives = 105/240 (43%), Gaps = 31/240 (12%) Query: 22 IIGG--TECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVT 75 ++ G T +M L CGG LI+ ++VLTA C + Sbjct: 1 VVNGIPTRTNIG---WMVSLRYR----NKHICGGSLIKESWVLTARQCFPSRDLKDYEAW 53 Query: 76 LGAHNI--TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 LG H++ +E Q L V + P+ + D++L+KL A L V T+ P+ Sbjct: 54 LGIHDVHGRGDEKCKQVLNVSQLVYGPEGS------DLVLMKLARPAVLDDFVSTIDLPN 107 Query: 134 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFR---DFDHNLQLCVG 190 + +P C V GWG TG++ L+ L +M + CS + ++C G Sbjct: 108 YGSTIPEKTSCSVYGWGYTGLINY-DGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG 166 Query: 191 NPRKTKSAFKGDSGGPLLCAG----VAQGIVSYGRSDA--KPPAVFTRISHYRPWINQIL 244 + +GD GGPL+C + G++ GR A P +F R+++Y WI++I+ Sbjct: 167 AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >5XW8-A nrPDB Length = 133 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 53/134 (39%), Positives = 69/134 (51%), Gaps = 7/134 (5%) Query: 20 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 79 +I+GG C +S PY L N S FCGG LI +V++AAHC I V LG H Sbjct: 7 DKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEH 61 Query: 80 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 139 NI E Q + K HP +N +TL +DIML+KL A+L V T+ P + Sbjct: 62 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SCAA 119 Query: 140 PGRMCRVAGWGRTG 153 G C ++GWG T Sbjct: 120 AGTECLISGWGNTK 133 >3H7O-A nrPDB Length = 228 Score = 180 bits (458), Expect = 4e-46, Method: Composition-based stats. Identities = 53/229 (23%), Positives = 90/229 (39%), Gaps = 9/229 (3%) Query: 24 GGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAHNI 81 GG + P+ + S CGG ++ + FVLTAAHC + T+ + + Sbjct: 2 GGEKTDIKQVPWTVAVR-TYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYEST 60 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASL-TLAVGTLPFPSQFNFVPP 140 ED + + Y T+ +DI +L+L L L P Sbjct: 61 NLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 141 GRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQ-LCVGNPRKTKSA 198 G V+G+G + P L+ +L ++D C + + +LQ C + S Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA--QKVGVSL 178 Query: 199 FKGDSGGPLLCAGVAQGIVS-YGRSDAKPPAVFTRISHYRPWINQILQA 246 GD+G P + G+ + + + P VFT++ Y WI I++ Sbjct: 179 ESGDAGDPTVQQDTLVGVAAYFPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >1M9U-A nrPDB Length = 241 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 69/239 (28%), Positives = 96/239 (40%), Gaps = 22/239 (9%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTLG 77 +IGGT P P+ + S S CG L+ L+A+HC +I V G Sbjct: 1 VIGGTNASPGEFPWQLS-QQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 78 AHNITEEEDTWQKLEVIKQFRHPKYNTST--LHHDIMLLKLKEKASLTLAVGTLPFPSQF 135 ++ T Q V H Y T +DI +L L SL + P+ Sbjct: 60 LWQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH-----NLQLCVG 190 N G C ++GWGRT D LQ+ + ++ C+ + +CV Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 191 NPRKTKSAFKGDSGGPLLCA-------GVAQGIVSYGRSDAKP--PAVFTRISHYRPWI 240 +P A GDSGGPL C GV +VS G P P+V+TR+S Y WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 >3H7T-A nrPDB Length = 235 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 53/234 (22%), Positives = 92/234 (39%), Gaps = 13/234 (5%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG + P+ + + FCGG ++ NFV+TAA C + + H Sbjct: 1 IIGGKKSDITKEPWAVGVLV----DEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTL-AVGTLPFPSQFNFVPP 140 + T + K+ +Y+ T+ ++ +++ + L + PS P Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEP 116 Query: 141 GRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACSHFR------DFDHNLQLCVGNPR 193 V+GWG T S L E ++D ++C + ++ C G Sbjct: 117 DTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEY 176 Query: 194 KTKSAFKGDSGGPLLCAGVAQGIVSYGRS-DAKPPAVFTRISHYRPWINQILQA 246 GD+G P + G G+ SY S ++ P+VF R+ +Y I I+ Sbjct: 177 DETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDIISG 230 >2PKA-B nrPDB Length = 152 Score = 170 bits (431), Expect = 5e-43, Method: Composition-based stats. Identities = 50/152 (32%), Positives = 72/152 (47%), Gaps = 9/152 (5%) Query: 103 NTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGV---LKPGS 159 + HD+MLL+L+ A +T AV L P+Q + G C +GWG Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 160 DTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVS 218 D +Q V+L L+ C+ D LC G K GDSGGPL+C G+ QGI S Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITS 119 Query: 219 YG---RSDAKPPAVFTRISHYRPWINQILQAN 247 +G A P+++T++ Y WI+ + N Sbjct: 120 WGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >3VGC-B nrPDB Length = 131 Score = 166 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 50/134 (37%), Positives = 68/134 (50%), Gaps = 4/134 (2%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-AGRSITVTLGAHN 80 I+ G E P S P+ L+ T FCGG LI N+V+TAAHC S V G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKT---GFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 57 Query: 81 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 140 + QKL++ K F++ KYN+ T+++DI LLKL AS + V + PS + Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 117 Query: 141 GRMCRVAGWGRTGV 154 G C GWG T Sbjct: 118 GTTCVTTGWGLTRY 131 >2JET-B nrPDB Length = 128 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 46/131 (35%), Positives = 69/131 (52%), Gaps = 4/131 (3%) Query: 25 GTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-AGRSITVTLGAHNITE 83 G + P S P+ L+ T FCGG LI ++V+TAAHC S V G + Sbjct: 1 GEDAIPGSWPWQVSLQDKT---GFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGS 57 Query: 84 EEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRM 143 +E+ Q L++ + F++PK+N T+ +DI LLKL A + V + P+ + PPG + Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 144 CRVAGWGRTGV 154 C GWG+T Sbjct: 118 CATTGWGKTKY 128 >1RIW-B nrPDB Length = 147 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 17/149 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 72 ITVTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 + V +G H+ T E +K+ + K + HP+YN L DI L+KLK+ + + + + Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWGRTGVL 155 P + + + G RV GWG Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 151 bits (383), Expect = 2e-37, Method: Composition-based stats. Identities = 43/149 (28%), Positives = 63/149 (42%), Gaps = 17/149 (11%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSIT--- 73 I+ G + + P+ L + CG LI +VLTAAHC ++ T Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 74 --VTLGAHNITEEEDTWQKLEV-IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTL 129 V +G H+ T E +K+ + K + HP+YN L DI LLKLK L+ + + Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 130 PFPSQ---FNFVPPGRMCRVAGWGRTGVL 155 P + + G RV GWG Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2WIN-I nrPDB Length = 507 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 91/238 (38%), Gaps = 56/238 (23%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQK 90 H +P+ A + ++ + + C G ++ FVLTAAHC TV H+I ++ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 287 Query: 91 -LEVIKQFRHPKYN---------TSTLHHDIMLLKLKEKASLTLAVGTLPFP-----SQF 135 LE+ HP YN +D+ L+KLK K + + P ++ Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 347 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQ-ACSHFRDF 181 +PP C+ + L P D T +EV ++ D + +C + Sbjct: 348 LRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 403 Query: 182 -------------DHNLQLCVGN--PRKTKSAFKGDSGGPLLCAG----VAQGIVSYG 220 LC G P + +GDSGGPL+ + G++S+G Sbjct: 404 APGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 >1DLE-A nrPDB Length = 298 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 91/238 (38%), Gaps = 56/238 (23%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQK 90 H +P+ A + ++ + + C G ++ FVLTAAHC TV H+I ++ Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 80 Query: 91 -LEVIKQFRHPKYN---------TSTLHHDIMLLKLKEKASLTLAVGTLPFP-----SQF 135 LE+ HP YN +D+ L+KLK K + + P ++ Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 140 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQ-ACSHFRDF 181 +PP C+ + L P D T +EV ++ D + +C + Sbjct: 141 LRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 196 Query: 182 -------------DHNLQLCVGN--PRKTKSAFKGDSGGPLLCAG----VAQGIVSYG 220 LC G P + +GDSGGPL+ + G++S+G Sbjct: 197 APGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 >2OK5-A nrPDB Length = 752 Score = 140 bits (354), Expect = 4e-34, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 91/238 (38%), Gaps = 56/238 (23%) Query: 31 HSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQK 90 H +P+ A + ++ + + C G ++ FVLTAAHC TV H+I ++ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 531 Query: 91 -LEVIKQFRHPKYN---------TSTLHHDIMLLKLKEKASLTLAVGTLPFP-----SQF 135 LE+ HP YN +D+ L+KLK K + + P ++ Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 591 Query: 136 NFVPPGRMCRVAGWGRTGVLKPGSD-------------TLQEVKLRLMDPQ-ACSHFRDF 181 +PP C+ + L P D T +EV ++ D + +C + Sbjct: 592 LRLPPTTTCQ----QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 647 Query: 182 -------------DHNLQLCVGN--PRKTKSAFKGDSGGPLLCAG----VAQGIVSYG 220 LC G P + +GDSGGPL+ + G++S+G Sbjct: 648 APGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 >1AKS-B nrPDB Length = 98 Score = 131 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 33/98 (33%), Positives = 50/98 (51%), Gaps = 3/98 (3%) Query: 153 GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAG 211 LQ +K ++ +C S + +CVG + K + +GDSGGP++C G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 212 VAQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 QGIVS+G A P V+T++ +Y WI Q + AN Sbjct: 61 QLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >2KAI-A nrPDB Length = 80 Score = 119 bits (300), Expect = 8e-28, Method: Composition-based stats. Identities = 34/82 (41%), Positives = 45/82 (54%), Gaps = 4/82 (4%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 81 IIGG EC+ +S P+ + + S CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGRECEKNSHPWQVAIY----HYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL 56 Query: 82 TEEEDTWQKLEVIKQFRHPKYN 103 E E+T Q V F HP +N Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >1EPT-B nrPDB Length = 82 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 70 RSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTL 129 I V LG HNI E Q + K HP +N +TL +DIML+KL A+L V T+ Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 130 PFPSQFNFVPPGRMCRVAGWGRTG 153 P + G C ++GWG T Sbjct: 61 SLPR--SCAAAGTECLISGWGNTK 82 >1BBR-E nrPDB Length = 109 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 12/105 (11%) Query: 153 GVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRK---TKSAFKGDSGGPLL 208 V + LQ V L L++ C + R + C G A +GDSGGP + Sbjct: 1 SVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFV 60 Query: 209 CA------GVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 245 GIVS+G + +T + + WI +++ Sbjct: 61 MKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 105 >2HNT-F nrPDB Length = 105 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 158 GSDTLQEVKLRLMDPQACSHF-RDFDHNLQLCVGN-PRKTK--SAFKGDSGGPLLCA--- 210 LQ V L +++ C R + C G P + K A +GDSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 211 ---GVAQGIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 245 GIVS+G + +T + + WI +++ Sbjct: 62 NNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 101 >3F1S-B nrPDB Length = 283 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 49/229 (21%), Positives = 84/229 (36%), Gaps = 32/229 (13%) Query: 34 PYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAHNITEEEDTWQKL 91 P+ L T++ FCGG +IR NFVLT A C+ R+ITV + Sbjct: 65 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMI 118 Query: 92 EVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF---NFVPPGRMCRVAG 148 ++ H +Y+ +D+ LL+L+ A + P + + + P ++G Sbjct: 119 KITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 178 Query: 149 WGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC----VGNPRKTKSAFKGDS 203 W R G S T + V L++ + C C V + Sbjct: 179 WARNGTDLGNSLTTRPV--TLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGS----- 231 Query: 204 GGPLLC-----AGVAQGIV-SYGRSDAKPPAVFTRISHYRPWINQILQA 246 ++ + G++ S + T++S Y W QI+ A Sbjct: 232 ---VVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >3RU4-E nrPDB Length = 96 Score = 101 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 9/98 (9%) Query: 157 PGSDTLQEVKLRLMDPQACSHFRDF-DHNLQLCVGNPRKTKSAFKGDSGGPLLCA----G 211 D LQ+ L L+ C + + +C G S+ GDSGGPL+C Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAW 58 Query: 212 VAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQAN 247 GIVS+G S P V+ R++ W+ Q L AN Sbjct: 59 TLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 96 >2I6S-A nrPDB Length = 517 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 47/231 (20%), Positives = 79/231 (34%), Gaps = 53/231 (22%) Query: 34 PYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQK-LE 92 P+ + + C G LI +VLTAAHC +L N+ + + W K Sbjct: 244 PWHVTI----KPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFL 299 Query: 93 VIKQFRHPKYNTSTLHH---------DIMLLKLKEKASLTLAVGTLPFP-----SQFNFV 138 + K P ++ + DI LLKL +K ++ + P + Sbjct: 300 IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRR 359 Query: 139 PPGRMCRVAGWGRTGVLKPGSDTL--------QEVKLRL---MDPQACS----------- 176 P G CR L ++ + L ++ +C+ Sbjct: 360 PQGSTCR----DHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFP 415 Query: 177 ---HFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQ----GIVSYG 220 R+ + LC G +S KG+SGG + + G+VS+G Sbjct: 416 NLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWG 465 >2JET-C nrPDB Length = 99 Score = 100 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 9/97 (9%) Query: 158 GSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCA----GV 212 + LQ+ L ++ C + ++ C G + GDSGGPL+C Sbjct: 5 TPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGVWT 62 Query: 213 AQGIVSYGRSDA--KPPAVFTRISHYRPWINQILQAN 247 GIVS+G P V++R++ PW+ QIL+AN Sbjct: 63 LAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILEAN 99 >3H5C-B nrPDB Length = 317 Score = 99.5 bits (247), Expect = 1e-21, Method: Composition-based stats. Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 14/161 (8%) Query: 34 PYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA--GRSITVTLGAHNITEEEDTWQKL 91 P+ L T++ FCGG +IR NFVLT A C+ R+ITV + Sbjct: 106 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMI 159 Query: 92 EVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF---NFVPPGRMCRVAG 148 ++ H +Y+ +D+ LL+L+ A + P + + + P ++G Sbjct: 160 KITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 219 Query: 149 WGRTGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLC 188 W R G S T + V L++ + C C Sbjct: 220 WARNGTDLGNSLTTRPV--TLVEGEECGQVLNVTVTTRTYC 258 >2HNT-C nrPDB Length = 70 Score = 79.9 bits (196), Expect = 9e-16, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 29/72 (40%), Gaps = 12/72 (16%) Query: 22 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----------AGRS 71 I+ G++ + P+ L + CG LI +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 72 ITVTLGAHNITE 83 + V +G H+ T Sbjct: 59 LLVRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 79.1 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 94 IKQFRHPKYN-TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ---FNFVPPGRMCRVAGW 149 K + HP+YN L DI L+KLK+ + + + + P + + + G RV GW Sbjct: 9 EKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGW 68 Query: 150 GRTGVL 155 G Sbjct: 69 GNLKET 74 >1P3E-A nrPDB Length = 215 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 18/121 (14%) Query: 38 YLEIVTSNGPSKFCGGFLIRRNFVLTAAHCA----GRSI----TVTLGAHNITEEEDTWQ 89 + +T G S C G LI N +LT HC RS +V G ++ T + Sbjct: 21 SIAYITFGGSS--CTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSA- 77 Query: 90 KLEVIKQFRHPKY-NTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAG 148 + + + Y NT +D ++K ++ VG N G +++G Sbjct: 78 --NMTEFYVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNLT--GTTIKISG 131 Query: 149 W 149 + Sbjct: 132 Y 132 >2PFE-A nrPDB Length = 186 Score = 36.7 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 16/29 (55%) Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPAV 229 GDSGGP L AQG+ S G D + + Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDCRSGGI 166 >2OUA-A nrPDB Length = 188 Score = 35.2 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 45/178 (25%), Gaps = 51/178 (28%) Query: 62 LTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKAS 121 +TA HC V++G + + F +D ++ + Sbjct: 31 VTAGHCGSVGTQVSIG---------NGRGVFERSVFP---------GNDAAFVRGTSNFT 72 Query: 122 LTLAVGTLPFP-----SQFNFVPPGR----MCRVAGW--GRTGVLKPGSDTLQEVKLRLM 170 LT V S + P G GW G Q L Sbjct: 73 LTNLVSRYNSGGYATVSGSSTAPIGSQVCRSGSTTGWYCGTIQARNQTVSYPQGTVHSLT 132 Query: 171 DPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPA 228 C+ GDSGG + AQG+ S G + + Sbjct: 133 RTSVCAEP----------------------GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >2EA3-A nrPDB Length = 189 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 15/28 (53%) Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPA 228 GDSGG LL AQG+ S G + + Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >5ILB-A nrPDB Length = 474 Score = 34.4 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 27/89 (30%), Gaps = 19/89 (21%) Query: 26 TECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEE 85 +S P+ + ++ F+I +LT AHC V + + Sbjct: 17 HTAPDYSLPWQKQRQFTSTGS------AFMIGDGKLLTNAHCVEHDTQVKV-------KR 63 Query: 86 DTWQKLEVIKQFRHPKYNTSTLHHDIMLL 114 + V K + DI LL Sbjct: 64 RGDDRKYVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 34.4 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 27/89 (30%), Gaps = 19/89 (21%) Query: 26 TECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEE 85 +S P+ + ++ F+I +LT AHC V + + Sbjct: 57 HTAPDYSLPWQKQRQFTSTGS------AFMIGDGKLLTNAHCVEHDTQVKV-------KR 103 Query: 86 DTWQKLEVIKQFRHPKYNTSTLHHDIMLL 114 + V K + DI LL Sbjct: 104 RGDDRKYVAKVLV------RGVDCDIALL 126 >2SFA-A nrPDB Length = 191 Score = 32.5 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 13/28 (46%) Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPA 228 GDSGG L A G+ S G + + Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >5JYK-A nrPDB Length = 566 Score = 31.3 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 17/45 (37%), Gaps = 6/45 (13%) Query: 32 SRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTL 76 S P+ + + + GF+I VLT AH V L Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHTQVKL 153 >3LT3-A nrPDB Length = 217 Score = 31.3 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 58/166 (34%), Gaps = 30/166 (18%) Query: 53 GFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIM 112 GF+I + V+T AH V G++N+T E Y+ S D+ Sbjct: 42 GFVISPDRVMTNAH-------VVAGSNNVTVYAGDK-PFEATVV----SYDPSV---DVA 86 Query: 113 LLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDP 172 +L A L L F ++ G V G+ G ++E +RL P Sbjct: 87 IL-----AVPHLPPPPLVFAAEPAKT--GADVVVLGYPGGGNFTATPARIREA-IRLSGP 138 Query: 173 QACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLL-CAGVAQGIV 217 ++ +GD+GGPL+ G G+V Sbjct: 139 DIYGDPEPVTRDV------YTIRADVEQGDAGGPLIDLNGQVLGVV 178 >1DUE-A nrPDB Length = 242 Score = 31.0 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 39/108 (36%), Gaps = 16/108 (14%) Query: 53 GFLIRRNFVLTAAHC--------AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNT 104 G LI +N VLT H + S ++ + E + + EV + + P Sbjct: 59 GVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEP---- 114 Query: 105 STLHHDIMLLKLKEK---ASLTLAVGTLPFPSQFNFVPPGRMCRVAGW 149 D+ L++LK SL + + N + G + G+ Sbjct: 115 FGAGVDLALIRLKPDQNGVSLGDKISPAKIGT-SNDLKDGDKLELIGY 161 >2SGA-A nrPDB Length = 181 Score = 31.0 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 13/28 (46%) Query: 201 GDSGGPLLCAGVAQGIVSYGRSDAKPPA 228 GDSGG L A G+ S G + + Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGG 162 >5ILA-A nrPDB Length = 301 Score = 31.0 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 17/45 (37%), Gaps = 6/45 (13%) Query: 32 SRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTL 76 S P+ + + + GF+I VLT AH V L Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHTQVKL 153 >4NCX-A nrPDB Length = 506 Score = 30.6 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 17/38 (44%) Query: 111 IMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAG 148 + L + + +L+ A+ L P +PP C +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >3TJO-A nrPDB Length = 231 Score = 30.2 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 51/170 (30%), Gaps = 39/170 (22%) Query: 53 GFLIRRN-FVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDI 111 GF++ + ++T AH V + N E + ++ DI Sbjct: 67 GFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKA--------------DI 112 Query: 112 MLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLR--L 169 L+K+ + L + + + + PG G +LQ + Sbjct: 113 ALIKIDHQGKL-----PVLLLGRSSELRPGEFVVAIG---------SPFSLQNTVTTGIV 158 Query: 170 MDPQACSHFRDFDHNLQLCVGNPRKTKSAF--KGDSGGPLL-CAGVAQGI 216 Q ++ A G++GGPL+ G GI Sbjct: 159 STTQRGGKELGLRNSDM-----DYIQTDAIINYGNAGGPLVNLDGEVIGI 203 >3NUM-A nrPDB Length = 332 Score = 30.2 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 51/170 (30%), Gaps = 39/170 (22%) Query: 53 GFLIRRN-FVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDI 111 GF++ + ++T AH V + N E + ++ DI Sbjct: 50 GFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKA--------------DI 95 Query: 112 MLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLR--L 169 L+K+ + L + + + + PG G +LQ + Sbjct: 96 ALIKIDHQGKL-----PVLLLGRSSELRPGEFVVAIG---------SPFSLQNTVTTGIV 141 Query: 170 MDPQACSHFRDFDHNLQLCVGNPRKTKSAF--KGDSGGPLL-CAGVAQGI 216 Q ++ A G++GGPL+ G GI Sbjct: 142 STTQRGGKELGLRNSDM-----DYIQTDAIINYGNAGGPLVNLDGEVIGI 186 >4V1Y-A nrPDB Length = 494 Score = 30.2 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 23/59 (38%), Gaps = 6/59 (10%) Query: 56 IRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKY-NTSTLHHDIML 113 + ++V H I V LG H + + ++ + P + N T + I+L Sbjct: 41 LGDSWV----HVQDGRI-VALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILL 94 >3H7V-A nrPDB Length = 330 Score = 30.2 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 30/92 (32%), Gaps = 10/92 (10%) Query: 62 LTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKAS 121 LT A RS G + ED ++ + P + + TL+ DI L + Sbjct: 16 LTTAQGVWRS---RSGIY--LRLEDEQGQVGYGEIAPLPGWGSETLNADIALCQ-----Q 65 Query: 122 LTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTG 153 L + + +P + W G Sbjct: 66 LPGHLTPEIMATIPEALPAAQFGFATAWQSVG 97 >4JCN-A nrPDB Length = 216 Score = 28.6 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 16/120 (13%), Positives = 36/120 (30%), Gaps = 14/120 (11%) Query: 37 AYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSI----TVTLGAHNITEEEDTWQKLE 92 + +G G ++ N +LT H + +++ E + K Sbjct: 22 VSFIYIPIDGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFV 81 Query: 93 VIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFP---SQFNFVPPGRMCRVAGW 149 + +P + D+ +L++ +G + P S V G+ Sbjct: 82 GQEIIPYPG------NSDLAILRVS-PNEHNQHIGQVVKPATISSNTDTRINENITVTGY 134 >4FVB-A nrPDB Length = 152 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 201 GDSGGPLLCAGVAQGIVSYGRS 222 GD+GG L C GIVS G + Sbjct: 110 GDAGGILRCQHGVVGIVSTGGN 131 >3W95-A nrPDB Length = 171 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 201 GDSGGPLLCAGVAQGIVSYGRS 222 GD+GG L C GIVS G + Sbjct: 129 GDAGGILRCQHGVVGIVSTGGN 150 >1HPG-A nrPDB Length = 187 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 12/33 (36%), Gaps = 2/33 (6%) Query: 198 AFK--GDSGGPLLCAGVAQGIVSYGRSDAKPPA 228 A GDSGG VA GI S + Sbjct: 136 ACSAGGDSGGAHFAGSVALGIHSGSSGCSGTAG 168 >1Q2Q-A nrPDB Length = 363 Score = 28.3 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 12/29 (41%) Query: 217 VSYGRSDAKPPAVFTRISHYRPWINQILQ 245 VS G DA+ V T + W+ + Sbjct: 213 VSPGMLDAQAYGVKTNVQDMANWVMANMA 241 >6F07-A nrPDB Length = 620 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%), Gaps = 2/33 (6%) Query: 86 DTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKE 118 D Q L+ F HP + L +DI +++LK Sbjct: 522 DKVQLLDSGDSFYHPVFKI--LQNDIKIIELKN 552 >3LEC-A nrPDB Length = 230 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 8/43 (18%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNG 46 LP+ LL C A AGE++ G PY + L+ V+ +G Sbjct: 35 LPIFLLQMGYCDFAIAGEVVNG--------PYQSALKNVSEHG 69 >2HRV-A nrPDB Length = 142 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 14/27 (51%), Gaps = 1/27 (3%) Query: 195 TKSAFK-GDSGGPLLCAGVAQGIVSYG 220 + + GD GG LLC GIV+ G Sbjct: 97 GEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >6HQA-B nrPDB Length = 722 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 19/49 (38%), Gaps = 1/49 (2%) Query: 85 EDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 133 + + + P + L +DI +++ +A + L+ PS Sbjct: 333 DPSDENNPSKDTLPLPLKSAQDLRNDIAMIQ-DSRAKIKLSAAQASLPS 380 >4BF7-A nrPDB Length = 352 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 22/62 (35%), Gaps = 3/62 (4%) Query: 94 IKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTG 153 + + +P + L ++ L+L ++ L + PG +GW T Sbjct: 63 QRIWVNPSDGSYNLEYN---LELAKRVQDAGMSVYLDLHLSDTWADPGDQATPSGWSTTD 119 Query: 154 VL 155 + Sbjct: 120 ID 121 >4ASC-A nrPDB Length = 315 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 14/30 (46%) Query: 4 LPLPLLLFLLCSRAEAGEIIGGTECKPHSR 33 LP P LF L + ++GG E K R Sbjct: 85 LPSPRCLFGLGEALNSIYVVGGREIKDGER 114 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.157 0.573 Lambda K H 0.267 0.0483 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,530,008 Number of Sequences: 36641 Number of extensions: 503747 Number of successful extensions: 2609 Number of sequences better than 10.0: 194 Number of HSP's better than 10.0 without gapping: 311 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 1016 Number of HSP's gapped (non-prelim): 375 length of query: 247 length of database: 10,336,785 effective HSP length: 95 effective length of query: 152 effective length of database: 6,855,890 effective search space: 1042095280 effective search space used: 1042095280 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.7 bits)