BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23921 (792 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5D1Y-A nrPDB 1658 0.0 2WGH-A nrPDB 1402 0.0 2ZLF-A nrPDB 1118 0.0 5IM3-A nrPDB 570 e-163 5R1R-A nrPDB 248 8e-66 6DQW-A nrPDB 217 1e-56 6DQX-A nrPDB 194 1e-49 6CGM-A nrPDB 184 1e-46 1PEQ-A nrPDB 178 9e-45 3O0O-A nrPDB 171 1e-42 3MPI-A nrPDB 33 0.39 4V7E-CC nrPDB 31 1.9 4V3P-LD nrPDB 31 2.2 6NUW-E nrPDB 30 3.4 2O1B-A nrPDB 30 3.8 2G8G-A nrPDB 30 5.0 1QS0-B nrPDB 29 7.5 >5D1Y-A nrPDB Length = 812 Score = 1658 bits (4294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 792/792 (100%), Positives = 792/792 (100%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA Sbjct: 21 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 80 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST Sbjct: 81 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 140 Query: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK Sbjct: 141 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 200 Query: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL Sbjct: 201 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 260 Query: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY Sbjct: 261 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 320 Query: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD Sbjct: 321 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 380 Query: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL Sbjct: 381 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 440 Query: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI 480 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI Sbjct: 441 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI 500 Query: 481 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL 540 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL Sbjct: 501 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL 560 Query: 541 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA 600 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA Sbjct: 561 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA 620 Query: 601 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII 660 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII Sbjct: 621 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII 680 Query: 661 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL 720 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL Sbjct: 681 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL 740 Query: 721 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS 780 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS Sbjct: 741 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS 800 Query: 781 LENRDECLMCGS 792 LENRDECLMCGS Sbjct: 801 LENRDECLMCGS 812 >2WGH-A nrPDB Length = 676 Score = 1402 bits (3629), Expect = 0.0, Method: Compositional matrix adjust. Identities = 668/668 (100%), Positives = 668/668 (100%) Query: 75 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 134 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA Sbjct: 2 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 61 Query: 135 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 194 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS Sbjct: 62 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 121 Query: 195 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 254 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC Sbjct: 122 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 181 Query: 255 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 314 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL Sbjct: 182 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 241 Query: 315 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 374 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY Sbjct: 242 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 301 Query: 375 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 434 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE Sbjct: 302 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 361 Query: 435 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS 494 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS Sbjct: 362 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS 421 Query: 495 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE 554 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE Sbjct: 422 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE 481 Query: 555 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN 614 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN Sbjct: 482 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN 541 Query: 615 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD 674 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD Sbjct: 542 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD 601 Query: 675 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT 734 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT Sbjct: 602 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT 661 Query: 735 GMYYLRTR 742 GMYYLRTR Sbjct: 662 GMYYLRTR 669 >2ZLF-A nrPDB Length = 888 Score = 1118 bits (2893), Expect = 0.0, Method: Compositional matrix adjust. Identities = 512/765 (66%), Positives = 638/765 (83%), Gaps = 7/765 (0%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 M+V KRDGR+E V FDKIT+RI +LCYGL+ +D ++T ++I G+Y GVTT+ELD LA Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 AET A +TT HPDYA LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 Query: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 +IV+ NKD+LNSAI+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 Query: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 DI+AA+ETYNL+S ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CAL Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 Query: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 ISK+AGGIG+ + IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+Y Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 Query: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 LEPWH DIF+F+D++KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 Query: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 + +G+EFE LY YEK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NL Sbjct: 361 DCYGDEFEALYTRYEKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419 Query: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-TSE----HTYDFKKLAEVTKVVVR 475 G IK SNLC EIVEY++ DE AVCNLAS+AL ++ TSE TY+FKKL E+ KVV R Sbjct: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTR 479 Query: 476 NLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETI 535 NLN++ID NYYPV EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETI Sbjct: 480 NLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETI 539 Query: 536 YYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRN 595 Y+ ++EASC+LA++ GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RN Sbjct: 540 YHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRN 599 Query: 596 SLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEM 655 SL +APMPTAST+QILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E M Sbjct: 600 SLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGM 659 Query: 656 KNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 715 K +I NGSIQ +P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P Sbjct: 660 KQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAP 719 Query: 716 NYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDK 760 GKLTSMHFYGWK+GLKTGMYYLRT+ A+ IQFT++ +K+ D+ Sbjct: 720 TMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID-QKIADQ 763 >5IM3-A nrPDB Length = 963 Score = 570 bits (1469), Expect = e-163, Method: Compositional matrix adjust. Identities = 319/784 (40%), Positives = 460/784 (58%), Gaps = 34/784 (4%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 + + + DG + ++ + I + C GL VD A I + ++ LY GV +++T Sbjct: 148 IRITRADGSLSPLDMGRLNTIISEACEGLAE--VDGALIERETLKNLYDGVAEKDVNTAL 205 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 TA TL + P+Y+ + AR+ + L E ++ + K P + Sbjct: 206 VMTARTLVEREPNYSYVTARLLMDTLRAEALGFLGVAESATHHEMAELYAKALPAYIEKG 265 Query: 121 LDIVLANK-------DRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMR 173 + L + ++L AI ++RD + Y G +TL Y + +G E PQ MR Sbjct: 266 AEFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDRYFIHKDGIRFELPQIFFMR 325 Query: 174 VSVGIHKEDIDA---AIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEG 230 V++G+ E+ D AIE YNLLS + ++PTLFNAGT RPQLSSC+L ++ DD + G Sbjct: 326 VAMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTLFNAGTLRPQLSSCYLTTVPDD-LSG 384 Query: 231 IYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGG 290 IY + A++SK AGG+G + +RA GSYI GTNG S G+VP L+V N+TA V+QGG Sbjct: 385 IYGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQGG 444 Query: 291 NKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSL 350 KR GA YLE WHLDI EFL+L+KNTG + +R D+ A WIPDLFMKRV + W+L Sbjct: 445 -KRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDGSWTL 503 Query: 351 MCPNECPGLDEVWGEEFEKLYASYEKQG-----RVRKVVKAQQLWYAIIESQTETGTPYM 405 P++ P L +++G+ FE+ Y YE ++ KVV+A+ LW ++ ETG P++ Sbjct: 504 FSPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHKVVQAKDLWRKMLSMLFETGHPWL 563 Query: 406 LYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKK 465 +KD CN +S QQ++G + SNLCTEI T+KDE+AVCNL S+ L ++ + D K Sbjct: 564 TFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIV-DGKLDTAK 622 Query: 466 LAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQ 525 L + K VR L+ +IDINYY VP+A SN +HRP+G+G+ G DA L P+ S A Sbjct: 623 LEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLGIMGFQDALYLQHIPYGSDAAI 682 Query: 526 LLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYD------------MWNV 573 Q E I Y A++ASCDLA E+G Y+T++GS S+GIL D V Sbjct: 683 AFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQGILPIDSEKKLIEERGAKYIEV 742 Query: 574 TPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGE 633 ++ DW L+E++ K GIRNS ++A PTA+ A I G ++SIEP N+Y + LSGE Sbjct: 743 DLSETLDWAPLRERVQK-GIRNSNIMAIAPTATIANITGVSQSIEPTYQNLYVKSNLSGE 801 Query: 634 FQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLK 693 F ++NP+L++DL RGLW M N + +GS+Q I IP DLK LY T +E+ + +++ Sbjct: 802 FTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDLYATAFEVETRWIVE 861 Query: 694 MAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN 753 A+ R +IDQ+QSLN++IA + KL + W +GLKT YYLR A + + T+N Sbjct: 862 AASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGLKT-TYYLRALAATSTEKSTIN 920 Query: 754 KEKL 757 KL Sbjct: 921 TGKL 924 >5R1R-A nrPDB Length = 761 Score = 248 bits (633), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 215/784 (27%), Positives = 342/784 (43%), Gaps = 85/784 (10%) Query: 3 VIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAE 62 V KRDG ER+ DKI + GL+ V +Q+ ++ Y G+ T ++ + Sbjct: 7 VTKRDGSTERINLDKIHRVLDWAAEGLHN--VSISQVELRSHIQFYDGIKTSDIHETIIK 64 Query: 63 TAATLTTKH-PDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINP--HNGKHSPMVAKS 119 AA L ++ PDY LAAR+A+ +L K+ F LY+++ GK+ + + Sbjct: 65 AAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPA--LYDHVVKMVEMGKYDNHLLE- 121 Query: 120 TLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLL--KINGKVAERPQHMLMRVSVG 177 D ++++ I +DRD +++Y K LE YL+ ++ G++ E Q + + V+ Sbjct: 122 --DYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAAC 179 Query: 178 I-----HKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIY 232 + + + Y+ +S + +P + T Q SSC L+ D S++ I Sbjct: 180 LFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGD-SLDSIN 238 Query: 233 DTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNK 292 T GIG+ IRA GS I G G +P + + + QGG Sbjct: 239 ATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG-V 297 Query: 293 RPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMC 352 R GA ++ WHL++ L LK N G E R R + + + I L R+ +D +L Sbjct: 298 RGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFS 357 Query: 353 PNECPGLDEVW---GEEFEKLYASYEKQGRVRKV-VKAQQLWYAIIESQTETGTPYMLYK 408 P++ PGL + + EEFE+LY YEK +RK VKA +L+ +++ + TG Y+ Sbjct: 358 PSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNV 417 Query: 409 DSCNRKSN-QQNLGTIKCSNLCTEIVEYT--------SKDEVAVCNLASLALNMYVTSEH 459 D CN S + ++ SNLC I T E+A+C L++ L Sbjct: 418 DHCNTHSPFDPAIAPVRQSNLCLAIALPTKPLNDVNDENGEIALCTLSAFNLGA------ 471 Query: 460 TYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPF 519 + +L E+ + VR L+ ++D YP+P A R +GIGV A + Sbjct: 472 INNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRY 531 Query: 520 ESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDL- 578 A L + FE I Y L+AS +LAKEQG + + +KGIL D + + Sbjct: 532 SDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIA 591 Query: 579 -----WDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGE 633 +DW+ L+E I +G+RNS L A MP+ +++QI IEP + + G Sbjct: 592 NEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGI 651 Query: 634 FQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEI-SQKTVL 692 + V P + L Y+ +WE+ L Sbjct: 652 LRQVVPDY--------------------------------EHLHDAYELLWEMPGNDGYL 679 Query: 693 KMAAERGAFIDQSQSLNIHIAEPNY--GKLTSMHFY-----GWKQGLKTGMYYLRTRPAA 745 ++ FIDQS S N + + GK+ +K G+KT +YY TR A Sbjct: 680 QLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKT-LYYQNTRDGA 738 Query: 746 NPIQ 749 Q Sbjct: 739 EDAQ 742 >6DQW-A nrPDB Length = 585 Score = 217 bits (553), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 179/612 (29%), Positives = 284/612 (46%), Gaps = 92/612 (15%) Query: 149 KTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAI-ETYNLLSER-WFTHASPTLF 206 + L R YLLK E + + R+ + + E++ + ER W + +SP Sbjct: 50 QILNRGYLLK-----GETVEGAIDRICTAAARRLYKPELKESFVEMIERGWMSISSPVWA 104 Query: 207 NAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTN 266 N GT R SCF + + D IEGI L + + +K GG +R GS + N Sbjct: 105 NMGTERGLPISCFNVHVPD-KIEGITHKLGEVIMQTKIGGGTSGYFGELRERGSAVT-DN 162 Query: 267 GNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRAR 326 G S+G V +++++ + QGG +R GAFA YL+ H DI EFL + K+ G Q Sbjct: 163 GKSSGAVSFMKLFDTAMDTISQGGVRR-GAFAAYLDIDHPDIEEFLKI-KSIGNPIQ--- 217 Query: 327 DLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKA 386 +LF + +PD +M+ + + Sbjct: 218 NLFTGICVPDYWMQEM-------------------------------------IDGDADK 240 Query: 387 QQLWYAIIESQTETGTPYMLYKDSCNRKSNQ----QNLGTIKCSNLCTEIVEYTSKDEVA 442 +Q+W ++ES+ + G PY+ + D+ N+ Q QNL I SNLC+EI+ ++ DE Sbjct: 241 RQIWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDESF 299 Query: 443 VCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIG 502 +C L+S+ L +Y + T K V++ + + NYY + A KRHR +G Sbjct: 300 ICCLSSMNLELYEEWKDTEAVKLAIFFLDAVLQEFIEKTEGNYY-LSAANKFAKRHRALG 358 Query: 503 IGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVS 562 +GV G PFE EA++ +IF+ I A +AS +LA+ G E +G Sbjct: 359 LGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELARIYGEPELLKG---- 414 Query: 563 KGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNE-SIEPYT 621 YG RN+ +A PT S++ ILG IEP++ Sbjct: 415 ----------------------------YGRRNTTTMAIAPTTSSSAILGQTSPGIEPFS 446 Query: 622 SNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYK 681 SN Y + G F N +L K L E+GL +EE+ I+ GS+Q + ++ K ++K Sbjct: 447 SNYYKAGLSKGNFMRKNKYLKKLLEEKGLDNEEVWRGIMLNGGSVQHMSQLTQQEKDVFK 506 Query: 682 TVWEISQKTVLKMAAERGAFIDQSQSLNIHI-AEPNYGKLTSMHFYGWKQGLKTGMYYLR 740 T EISQ +++ A R F+DQ QSLN++I AE + + W+QG+K+ +YY R Sbjct: 507 TFKEISQLEIVQQAGIRQKFVDQGQSLNLNIPAELAIKDVNRLMIEAWQQGVKS-LYYQR 565 Query: 741 TRPAANPIQFTL 752 ++ + + +L Sbjct: 566 SQSVSKELVTSL 577 >6DQX-A nrPDB Length = 574 Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 187/605 (30%), Positives = 281/605 (46%), Gaps = 96/605 (15%) Query: 151 LERSYLLKINGKVA-ERPQHMLMRVSVGIHKEDIDA-AIETYNLLSERWFTHASPTLFNA 208 L+R YLL+ G A ER + + HK I+ A + Y+ ++ +F+ +SP N Sbjct: 41 LQRGYLLE--GTTALERIRFIAEHAE---HKLGIEGYADKFYHYMARGYFSLSSPIWSNF 95 Query: 209 GTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGN 268 G +R SCF S DSI I T + ++SK GG IR GS I NG Sbjct: 96 GLDRGLPISCFG-SYIGDSIHEIMVTTAEVGMMSKIGGGTSAYFGDIRPRGSAIK-NNGK 153 Query: 269 SNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDL 328 S+G ++++ + QG R G FA Y++ H DI E+LD+ Sbjct: 154 SDGSFNFSKLFDTVIDVISQG-TSRKGQFAGYIDIEHGDIDEWLDI-------------- 198 Query: 329 FFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQ 388 E N LM C G D W E K G K +Q Sbjct: 199 ------------HTEGNP-IQLMYYGVCVGHD--WLESM--------KAGDPYK----RQ 231 Query: 389 LWYAIIESQTETGTPYMLYKDSCNRKS----NQQNLGTIKCSNLCTEIVEYTSKDEVAVC 444 LW +++ +TETG PY+ +KD+ N +N+ T+ SNLCTEI+ +S DE VC Sbjct: 232 LWAKLLQRKTETGIPYLFFKDNANAGRPDVYKDKNM-TVHASNLCTEIMLPSSNDESFVC 290 Query: 445 NLASLALNMYVTSEHTYDFKKLAEVTKVVVRN-LNKIIDINYYPVPEACLSNKRHRPIGI 503 L+S+ L + + T + L VV+ + K D+ + + A RHR +G+ Sbjct: 291 CLSSMNLLYFDEWKDTEAPEVLTYFLDVVMSEFIEKSKDMPF--LDRAHRFATRHRALGL 348 Query: 504 GVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSK 563 GV G F+S +A N IF+T+ L+AS +LAK G E +G Sbjct: 349 GVLGWHSYLQANNIAFDSFQAMQKNNLIFKTLQEKTLKASQELAKRFGEPEILKG----- 403 Query: 564 GILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGN-NESIEPYTS 622 YG RN+ L++ PT S++ ILG+ + S+EP+ S Sbjct: 404 ---------------------------YGRRNTTLMSIAPTKSSSFILGSVSPSVEPFKS 436 Query: 623 NIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKT 682 N Y + + + NP L K L E+GL EE+ I+ +GS+Q + ++ D+ K+++KT Sbjct: 437 NYYVKDLAKIKTVYKNPFLEKLLQEKGLDTEEIWESILHNDGSVQHLEQLTDEEKEVFKT 496 Query: 683 VWEISQKTVLKMAAERGAFIDQSQSLNI--HIAEPNYGKLTSMHFYGWKQGLKTGMYYLR 740 EISQ +V++ AA+R +IDQ QS+NI H A P L ++ + GLK+ +YY Sbjct: 497 FSEISQLSVIQQAAQRQKYIDQGQSINIMVHPATPAR-DLNQLYLTAEELGLKS-IYYQY 554 Query: 741 TRPAA 745 + AA Sbjct: 555 SMSAA 559 >6CGM-A nrPDB Length = 700 Score = 184 bits (468), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 158/628 (25%), Positives = 292/628 (46%), Gaps = 83/628 (13%) Query: 155 YLLKINGK--VAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAG-TN 211 Y LK N K + ER + + V++ D + A E NL+ + + ++PT NAG Sbjct: 104 YALKTNDKKKILERYEDRISIVALFFANGDTEKAKEYVNLMINQEYQPSTPTFLNAGRKR 163 Query: 212 RPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNG 271 R +L SCFLL + +DS+ I + +SK GG+ + +S +RA G I + G Sbjct: 164 RGELVSCFLLEV-NDSLNDISRAIDISMQLSKLGGGVSLNLSKLRAKGEAIKDVENATKG 222 Query: 272 LVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFA 331 +V ++++ +N RY DQ G +R G+ A YL +H DI +FLD KK + E+ R + L Sbjct: 223 VVGVMKLLDNAFRYADQMG-QRQGSGAAYLNIFHRDINDFLDTKKISADEDVRVKTLSIG 281 Query: 332 LWIPDLFMKRVETNQDWSLMCPNEC-----PGLDEVWGEEFEKLYASYEKQGRVRK-VVK 385 + IPD F++ ++ + P+ +DE+ + ++Y + RV+K + Sbjct: 282 VVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMDEM---DMNEMYDKFVDNPRVKKEKIN 338 Query: 386 AQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE---------YT 436 ++L + ++E+G PY++++D+ N+ ++ +K SNLC+E+++ Y Sbjct: 339 PRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVKFSNLCSEVLQASQVSSYTDYD 398 Query: 437 SKDEVAV---CNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIID-INYYPVPEAC 492 +DE+ + CNL S LN+ EH K + + K+ +L + + + P Sbjct: 399 EEDEIGLDISCNLGS--LNILNVMEH----KSIEKTVKLATDSLTHVSETTDIRNAPAVR 452 Query: 493 LSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQG- 551 +NK + IG+G L +ES EA+ F + + +++ S ++AKE+G Sbjct: 453 RANKAMKSIGLGAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEIAKEKGE 512 Query: 552 PYETYEGSPVSKG--ILQYDMWNVTP-----TDLW---------DWKVLKEKIAKYGIRN 595 ++ YEGS + G +Y + +P +L+ DWK LK +A++G+ + Sbjct: 513 TFDQYEGSTYATGEYFDKYVSTDFSPKYEKIANLFEGMHIPTTEDWKKLKAFVAEHGMYH 572 Query: 596 SLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEM 655 S + PT S + + + S+ P +++ + ER + + Sbjct: 573 SYRLCIAPTGSISYVQSSTASVMP---------------------IMERIEERTYGNSK- 610 Query: 656 KNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 715 + +P + + YK +++ V+ M A IDQ S + + + Sbjct: 611 ---------TYYPMPGLASNNWFFYKEAYDMDMFKVVDMIATIQQHIDQGISFTLFLKDT 661 Query: 716 NYGK-LTSMHFYGWKQGLKTGMYYLRTR 742 + L + Y +G+KT +YY RT+ Sbjct: 662 MTTRDLNRIDLYAHHRGIKT-IYYARTK 688 >1PEQ-A nrPDB Length = 714 Score = 178 bits (451), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 176/673 (26%), Positives = 285/673 (42%), Gaps = 95/673 (14%) Query: 122 DIVLANKDRLNSAIIYDR----DFSYNYF-GFKTLERSYLLK-INGK-VAERPQHMLMRV 174 D VLA DR +++ F + F G SY LK +GK E + + V Sbjct: 74 DAVLARYDRAFVLRLFEHAHASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEHFEDRVTMV 133 Query: 175 SVGIHKEDIDAAIE-TYNLLSERWFTHASPTLFNAG-TNRPQLSSCFLLSMKDDSIEGIY 232 ++ + + D A + T +LS R F A+PT N G R +L SCFLL ++D+ +E I Sbjct: 134 ALTLAQGDETLATQLTDEMLSGR-FQPATPTFLNCGKQQRGELVSCFLLRIEDN-MESIG 191 Query: 233 DTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNK 292 + +SK GG+ +S +R G+ I S+G++P++++ + Y +Q G Sbjct: 192 RAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLG-A 250 Query: 293 RPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMC 352 R GA A+YL H DI FLD K+ E+ R + L + IPD+ + + N +L Sbjct: 251 RQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFRLAKENAQMALFS 310 Query: 353 PNEC------PGLDEVWGEEFEKLYASYEKQGRVRKV-VKAQQLWYAIIESQTETGTPYM 405 P + P D E +++L A VRK + A+ + + E Q E+G PY+ Sbjct: 311 PYDIQRRYGKPFGDIAISERYDELIAD----PHVRKTYINARDFFQTLAEIQFESGYPYI 366 Query: 406 LYKDSCNRKSNQQNLGTIKCSNLCTEIVE------------YTSKDEVAVCNLASLALNM 453 +++D+ NR + G I SNLC+EI++ YT CNL SL + Sbjct: 367 MFEDTVNRANPIA--GRINMSNLCSEILQVNSASRYDDNLDYTHIGHDISCNLGSLNI-- 422 Query: 454 YVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYY-PVPEACLSNKRHRPIGIGVQGLADAF 512 H D + + +R L + D+++ VP N IG+G L Sbjct: 423 ----AHVMDSPDIGRTVETAIRGLTAVSDMSHIRSVPSIAAGNAASHAIGLGQMNLHGYL 478 Query: 513 ILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQG-PYETYEGSPVSKG--ILQY- 568 + S EA F TI + A+ S LA+E+G + + S + G QY Sbjct: 479 AREGIAYGSPEALDFTNLYFYTITWHAVHTSMRLARERGKTFAGFAQSRYASGDYFTQYL 538 Query: 569 -DMW--------------NVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGN 613 D W +T W L++ + +YGI N L A PT S + I Sbjct: 539 QDDWQPKTAKVRALFARSGITLPTREMWLKLRDDVMRYGIYNQNLQAVPPTGSISYINHA 598 Query: 614 NESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIP 673 SI P + I R+ + T R + P + Sbjct: 599 TSSIHPIVAKIEIRK--------------EGKTGRVYY----------------PAPFMT 628 Query: 674 DDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGK-LTSMHFYGWKQGL 732 ++ +Y+ ++I + ++ AE +DQ SL + + + + Y W++G+ Sbjct: 629 NENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGI 688 Query: 733 KTGMYYLRTRPAA 745 K+ +YY+R R A Sbjct: 689 KS-LYYIRLRQLA 700 >3O0O-A nrPDB Length = 644 Score = 171 bits (432), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 155/567 (27%), Positives = 257/567 (45%), Gaps = 84/567 (14%) Query: 190 YNLLSERWFTHASPTLFNAGTN-------RP--------------------QLSSCFLLS 222 + +L R F SPTLFNAG +P LS+CF++ Sbjct: 79 FRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVP 138 Query: 223 MKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNT 282 + DSIE I++ +K+ ALI+K GG+G S +R GS++AGT+G ++G V + V+N+ Sbjct: 139 V-GDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSA 197 Query: 283 ARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKK-NTGKEEQRARDLFFALWIPDLFMKR 341 V QG +R GA L H DI EF+D KK NTG+ A FF L Sbjct: 198 ISVVKQGSRRR-GALMGILNINHPDIEEFIDAKKENTGE----AVLNFFNL--------- 243 Query: 342 VETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETG 401 S+ P + + +++ E+ E L S+ + +RK VK ++L+ I + ++G Sbjct: 244 -------SVGFPMDKKEILKLYEEDGE-LELSHPRS-TIRKKVKIRELFRKIATNAWKSG 294 Query: 402 TPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTY 461 P + + N+ I +N C EI + CNL S+ + + + Sbjct: 295 DPGLAFLGEMNKYYPLYPHRKINSTNPCGEI----GLSDYEACNLGSIDVAKFYNNGFV- 349 Query: 462 DFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFES 521 D + L E+ ++ VR L+ +ID+N +P+ + + K R +G+G+ G AD + P+ S Sbjct: 350 DLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNS 409 Query: 522 AEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGS---------PVSKGILQYDMWN 572 EA+ + I A S +L KE+G + E S P + G+ YD Sbjct: 410 QEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYD--- 466 Query: 573 VTPTDLWDWKVLKE--KIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVL 630 ++E K+ K RN L+ PT S + I + +EP YTR V Sbjct: 467 ---------DEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFV- 516 Query: 631 SGEFQIVNPHLLKDLTERGLWHEEMKNQI---IACNGSIQSIPEIPDDLKQLYKTVWEIS 687 + E P L + R + E+ +I + GS++ IP++P+ +K+++ +I Sbjct: 517 TKEDGTKEPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDID 576 Query: 688 QKTVLKMAAERGAFIDQSQSLNIHIAE 714 L M ++D + S I++ + Sbjct: 577 PMDHLLMQDAFQRYVDNNISKTINMPQ 603 >3MPI-A nrPDB Length = 397 Score = 33.5 bits (75), Expect = 0.39, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 8/78 (10%) Query: 186 AIETYNLLSERWFTHASPT--LFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISK 243 I+T NL E+ +HASPT LF P+ + +L D ++ +L L S Sbjct: 196 GIKTSNL--EKLGSHASPTGELFLDNVKVPKEN---ILGKPGDGARIVFGSLNHTRL-SA 249 Query: 244 SAGGIGVAVSCIRATGSY 261 +AGG+G+A +C+ A Y Sbjct: 250 AAGGVGLAQACLDAAIKY 267 >4V7E-CC nrPDB Length = 405 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Query: 637 VNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAA 696 VN HL + L + + ++A I+++PE+P + +++ + SQ +K+ Sbjct: 119 VNVHLRRVAVASALAATSVPSLVLARGHRIETVPELPLVISDSAESIEKTSQ--AIKILK 176 Query: 697 ERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGL 732 + GA+ D ++ + P GK+ + + K L Sbjct: 177 QVGAYADAEKAKDSVGIRPGKGKMRNRRYINRKGPL 212 >4V3P-LD nrPDB Length = 372 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Query: 637 VNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAA 696 VN HL + L + + ++A I+++PE+P + +++ + SQ +K+ Sbjct: 119 VNVHLRRVAVASALAATSVPSLVLARGHRIETVPELPLVISDSAESIEKTSQ--AIKILK 176 Query: 697 ERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGL 732 + GA+ D ++ + P GK+ + + K L Sbjct: 177 QVGAYADAEKAKDSVGIRPGKGKMRNRRYINRKGPL 212 >6NUW-E nrPDB Length = 461 Score = 30.4 bits (67), Expect = 3.4, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 12/77 (15%) Query: 70 KHPDYAILAARIAV---SNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLA 126 KHP +L RI + +NL T + S E LYN ++ GK P++++ + Sbjct: 151 KHPSLPVLITRIQLFDSNNLFLSTPNIGSINKESLYNKLDKFQGK--PLISRRPYYVAFP 208 Query: 127 NKDRLNSAIIY---DRD 140 LNS II+ D+D Sbjct: 209 ----LNSPIIFHSVDKD 221 >2O1B-A nrPDB Length = 404 Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 21/134 (15%) Query: 104 YINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKV 163 Y+ N K D +A ++ I++D F+Y FGF S L NGK Sbjct: 186 YLTYPNNPTGSTATKEVFDEAIAKFKGTDTKIVHD--FAYGAFGFDAKNPSILASENGKD 243 Query: 164 AERPQHML--------MRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQL 215 + L RV + +D+ A++ Y TH + +F A Q Sbjct: 244 VAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQ-------THTNAGMFGA----LQD 292 Query: 216 SSCFLLSMKDDSIE 229 ++ + L+ DD +E Sbjct: 293 AAIYALNHYDDFLE 306 >2G8G-A nrPDB Length = 524 Score = 29.6 bits (65), Expect = 5.0, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 12/60 (20%) Query: 552 PYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEK----------IAKYGIRNSLLIAP 601 P T+ +PV+ I QY V+ DW++ KE+ + YG +NSLL AP Sbjct: 446 PATTFSSTPVNSFITQYSTGQVSVQI--DWEIQKERSKRWNPEVQFTSNYGQQNSLLWAP 503 >1QS0-B nrPDB Length = 338 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 3/97 (3%) Query: 16 DKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYA 75 D+I S + +L Y +F+ P + M G+Y G T + L T P Sbjct: 93 DQIVSEMARLRYRSAGEFIAPLTLRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNP 152 Query: 76 ILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKH 112 A + ++++ + +F + + LYN P +G H Sbjct: 153 YDAKGLLIASIECDDPVIFLE-PKRLYN--GPFDGHH 186 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5D1Y-A nrPDB 1152 0.0 2ZLF-A nrPDB 1035 0.0 2WGH-A nrPDB 946 0.0 5IM3-A nrPDB 914 0.0 5R1R-A nrPDB 761 0.0 1PEQ-A nrPDB 589 e-168 6DQW-A nrPDB 571 e-163 6CGM-A nrPDB 566 e-161 6DQX-A nrPDB 530 e-151 3O0O-A nrPDB 488 e-138 Sequences not found previously or not previously below threshold: 1L1L-A nrPDB 51 2e-06 2GAI-A nrPDB 36 0.048 4HZC-A nrPDB 35 0.12 3U27-C nrPDB 34 0.32 6AF0-A nrPDB 33 0.52 2RG9-A nrPDB 32 0.95 3EZK-A nrPDB 32 1.2 3CWV-A nrPDB 31 2.3 2QZU-A nrPDB 31 2.4 5XVU-A nrPDB 30 4.4 5K8D-B nrPDB 30 5.4 4BDV-B nrPDB 29 5.5 2R7E-B nrPDB 29 5.8 6DQU-A nrPDB 29 7.9 >5D1Y-A nrPDB Length = 812 Score = 1152 bits (2979), Expect = 0.0, Method: Composition-based stats. Identities = 792/792 (100%), Positives = 792/792 (100%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA Sbjct: 21 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 80 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST Sbjct: 81 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 140 Query: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK Sbjct: 141 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 200 Query: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL Sbjct: 201 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 260 Query: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY Sbjct: 261 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 320 Query: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD Sbjct: 321 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 380 Query: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL Sbjct: 381 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 440 Query: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI 480 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI Sbjct: 441 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKI 500 Query: 481 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL 540 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL Sbjct: 501 IDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGAL 560 Query: 541 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA 600 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA Sbjct: 561 EASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIA 620 Query: 601 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII 660 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII Sbjct: 621 PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQII 680 Query: 661 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL 720 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL Sbjct: 681 ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL 740 Query: 721 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS 780 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS Sbjct: 741 TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCS 800 Query: 781 LENRDECLMCGS 792 LENRDECLMCGS Sbjct: 801 LENRDECLMCGS 812 >2ZLF-A nrPDB Length = 888 Score = 1035 bits (2675), Expect = 0.0, Method: Composition-based stats. Identities = 509/765 (66%), Positives = 636/765 (83%), Gaps = 7/765 (0%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 M+V KRDGR+E V FDKIT+RI +LCYGL+ +D ++T ++I G+Y GVTT+ELD LA Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 AET A +TT HPDYA LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 Query: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 +IV+ NKD+LNSAI+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 Query: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 DI+AA+ETYNL+S ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CAL Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 Query: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 ISK+AGGIG+ + IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+Y Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 Query: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 LEPWH DIF+F+D++KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 Query: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 + +G+EFE LY YEK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NL Sbjct: 361 DCYGDEFEALYTRYEKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419 Query: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSE-----HTYDFKKLAEVTKVVVR 475 G IK SNLC EIVEY++ DE AVCNLAS+AL ++ + TY+FKKL E+ KVV R Sbjct: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTR 479 Query: 476 NLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETI 535 NLN++ID NYYPV EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETI Sbjct: 480 NLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETI 539 Query: 536 YYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRN 595 Y+ ++EASC+LA++ GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RN Sbjct: 540 YHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRN 599 Query: 596 SLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEM 655 SL +APMPTAST+QILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E M Sbjct: 600 SLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGM 659 Query: 656 KNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 715 K +I NGSIQ +P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P Sbjct: 660 KQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAP 719 Query: 716 NYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDK 760 GKLTSMHFYGWK+GLKTGMYYLRT+ A+ IQFT++ +K+ D+ Sbjct: 720 TMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID-QKIADQ 763 >2WGH-A nrPDB Length = 676 Score = 946 bits (2445), Expect = 0.0, Method: Composition-based stats. Identities = 668/669 (99%), Positives = 668/669 (99%) Query: 75 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 134 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA Sbjct: 2 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 61 Query: 135 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 194 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS Sbjct: 62 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 121 Query: 195 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 254 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC Sbjct: 122 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 181 Query: 255 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 314 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL Sbjct: 182 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 241 Query: 315 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 374 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY Sbjct: 242 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 301 Query: 375 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 434 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE Sbjct: 302 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 361 Query: 435 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS 494 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS Sbjct: 362 YTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLS 421 Query: 495 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE 554 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE Sbjct: 422 NKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE 481 Query: 555 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN 614 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN Sbjct: 482 TYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN 541 Query: 615 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD 674 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD Sbjct: 542 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD 601 Query: 675 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT 734 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT Sbjct: 602 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKT 661 Query: 735 GMYYLRTRP 743 GMYYLRTR Sbjct: 662 GMYYLRTRA 670 >5IM3-A nrPDB Length = 963 Score = 914 bits (2362), Expect = 0.0, Method: Composition-based stats. Identities = 319/784 (40%), Positives = 460/784 (58%), Gaps = 34/784 (4%) Query: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 + + + DG + ++ + I + C GL VD A I + ++ LY GV +++T Sbjct: 148 IRITRADGSLSPLDMGRLNTIISEACEGLAE--VDGALIERETLKNLYDGVAEKDVNTAL 205 Query: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 TA TL + P+Y+ + AR+ + L E ++ + K P + Sbjct: 206 VMTARTLVEREPNYSYVTARLLMDTLRAEALGFLGVAESATHHEMAELYAKALPAYIEKG 265 Query: 121 LDIVLANK-------DRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMR 173 + L + ++L AI ++RD + Y G +TL Y + +G E PQ MR Sbjct: 266 AEFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDRYFIHKDGIRFELPQIFFMR 325 Query: 174 VSVGIHKEDIDA---AIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEG 230 V++G+ E+ D AIE YNLLS + ++PTLFNAGT RPQLSSC+L ++ DD + G Sbjct: 326 VAMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTLFNAGTLRPQLSSCYLTTVPDD-LSG 384 Query: 231 IYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGG 290 IY + A++SK AGG+G + +RA GSYI GTNG S G+VP L+V N+TA V+QGG Sbjct: 385 IYGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQGG 444 Query: 291 NKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSL 350 KR GA YLE WHLDI EFL+L+KNTG + +R D+ A WIPDLFMKRV + W+L Sbjct: 445 -KRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDGSWTL 503 Query: 351 MCPNECPGLDEVWGEEFEKLYASYEKQG-----RVRKVVKAQQLWYAIIESQTETGTPYM 405 P++ P L +++G+ FE+ Y YE ++ KVV+A+ LW ++ ETG P++ Sbjct: 504 FSPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHKVVQAKDLWRKMLSMLFETGHPWL 563 Query: 406 LYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKK 465 +KD CN +S QQ++G + SNLCTEI T+KDE+AVCNL S+ L ++ + D K Sbjct: 564 TFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIV-DGKLDTAK 622 Query: 466 LAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQ 525 L + K VR L+ +IDINYY VP+A SN +HRP+G+G+ G DA L P+ S A Sbjct: 623 LEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLGIMGFQDALYLQHIPYGSDAAI 682 Query: 526 LLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYD------------MWNV 573 Q E I Y A++ASCDLA E+G Y+T++GS S+GIL D V Sbjct: 683 AFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQGILPIDSEKKLIEERGAKYIEV 742 Query: 574 TPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGE 633 ++ DW L+E++ K GIRNS ++A PTA+ A I G ++SIEP N+Y + LSGE Sbjct: 743 DLSETLDWAPLRERVQK-GIRNSNIMAIAPTATIANITGVSQSIEPTYQNLYVKSNLSGE 801 Query: 634 FQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLK 693 F ++NP+L++DL RGLW M N + +GS+Q I IP DLK LY T +E+ + +++ Sbjct: 802 FTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDLYATAFEVETRWIVE 861 Query: 694 MAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN 753 A+ R +IDQ+QSLN++IA + KL + W +GLKT YYLR A + + T+N Sbjct: 862 AASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGLKT-TYYLRALAATSTEKSTIN 920 Query: 754 KEKL 757 KL Sbjct: 921 TGKL 924 >5R1R-A nrPDB Length = 761 Score = 761 bits (1964), Expect = 0.0, Method: Composition-based stats. Identities = 216/787 (27%), Positives = 343/787 (43%), Gaps = 85/787 (10%) Query: 3 VIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAE 62 V KRDG ER+ DKI + GL+ V +Q+ ++ Y G+ T ++ + Sbjct: 7 VTKRDGSTERINLDKIHRVLDWAAEGLHN--VSISQVELRSHIQFYDGIKTSDIHETIIK 64 Query: 63 TAATLTTKH-PDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINP--HNGKHSPMVAKS 119 AA L ++ PDY LAAR+A+ +L K+ F LY+++ GK+ + + Sbjct: 65 AAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPA--LYDHVVKMVEMGKYDNHLLE- 121 Query: 120 TLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLL--KINGKVAERPQHMLMRVSVG 177 D ++++ I +DRD +++Y K LE YL+ ++ G++ E Q + + V+ Sbjct: 122 --DYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAAC 179 Query: 178 I-----HKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIY 232 + + + Y+ +S + +P + T Q SSC L+ DS++ I Sbjct: 180 LFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIEC-GDSLDSIN 238 Query: 233 DTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNK 292 T GIG+ IRA GS I G G +P + + + QGG Sbjct: 239 ATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGV- 297 Query: 293 RPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMC 352 R GA ++ WHL++ L LK N G E R R + + + I L R+ +D +L Sbjct: 298 RGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFS 357 Query: 353 PNECPGLDEVW---GEEFEKLYASYEKQGRVRKV-VKAQQLWYAIIESQTETGTPYMLYK 408 P++ PGL + + EEFE+LY YEK +RK VKA +L+ +++ + TG Y+ Sbjct: 358 PSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNV 417 Query: 409 DSCNRKSN-QQNLGTIKCSNLCTEIVEYT--------SKDEVAVCNLASLALNMYVTSEH 459 D CN S + ++ SNLC I T E+A+C L++ L Sbjct: 418 DHCNTHSPFDPAIAPVRQSNLCLAIALPTKPLNDVNDENGEIALCTLSAFNLGA------ 471 Query: 460 TYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPF 519 + +L E+ + VR L+ ++D YP+P A R +GIGV A + Sbjct: 472 INNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRY 531 Query: 520 ESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDL- 578 A L + FE I Y L+AS +LAKEQG + + +KGIL D + + Sbjct: 532 SDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIA 591 Query: 579 -----WDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGE 633 +DW+ L+E I +G+RNS L A MP+ +++QI IEP + + G Sbjct: 592 NEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGI 651 Query: 634 FQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEI-SQKTVL 692 + V P + L Y+ +WE+ L Sbjct: 652 LRQVVPDY--------------------------------EHLHDAYELLWEMPGNDGYL 679 Query: 693 KMAAERGAFIDQSQSLNIHIAEPNY--GKLTSMHFY-----GWKQGLKTGMYYLRTRPAA 745 ++ FIDQS S N + + GK+ +K G+KT +YY TR A Sbjct: 680 QLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKT-LYYQNTRDGA 738 Query: 746 NPIQFTL 752 Q L Sbjct: 739 EDAQDDL 745 >1PEQ-A nrPDB Length = 714 Score = 589 bits (1519), Expect = e-168, Method: Composition-based stats. Identities = 172/672 (25%), Positives = 282/672 (41%), Gaps = 93/672 (13%) Query: 122 DIVLANKDRLNSAIIYDR----DFSYNYF-GFKTLERSYLLK-INGKVA-ERPQHMLMRV 174 D VLA DR +++ F + F G SY LK +GK E + + V Sbjct: 74 DAVLARYDRAFVLRLFEHAHASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEHFEDRVTMV 133 Query: 175 SVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAG-TNRPQLSSCFLLSMKDDSIEGIYD 233 ++ + + D A + + + F A+PT N G R +L SCFLL ++D+ +E I Sbjct: 134 ALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFLLRIEDN-MESIGR 192 Query: 234 TLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKR 293 + +SK GG+ +S +R G+ I S+G++P++++ + Y +Q G R Sbjct: 193 AVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLG-AR 251 Query: 294 PGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCP 353 GA A+YL H DI FLD K+ E+ R + L + IPD+ + + N +L P Sbjct: 252 QGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFRLAKENAQMALFSP 311 Query: 354 NEC------PGLDEVWGEEFEKLYASYEKQGRVRKV-VKAQQLWYAIIESQTETGTPYML 406 + P D E +++L A VRK + A+ + + E Q E+G PY++ Sbjct: 312 YDIQRRYGKPFGDIAISERYDELIA----DPHVRKTYINARDFFQTLAEIQFESGYPYIM 367 Query: 407 YKDSCNRKSNQQNLGTIKCSNLCTEIVE------------YTSKDEVAVCNLASLALNMY 454 ++D+ NR + G I SNLC+EI++ YT CNL SL + Sbjct: 368 FEDTVNRANPIA--GRINMSNLCSEILQVNSASRYDDNLDYTHIGHDISCNLGSLNIA-- 423 Query: 455 VTSEHTYDFKKLAEVTKVVVRNLNKIIDINY-YPVPEACLSNKRHRPIGIGVQGLADAFI 513 H D + + +R L + D+++ VP N IG+G L Sbjct: 424 ----HVMDSPDIGRTVETAIRGLTAVSDMSHIRSVPSIAAGNAASHAIGLGQMNLHGYLA 479 Query: 514 LMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQG-PYETYEGSPVSKG--ILQY-- 568 + S EA F TI + A+ S LA+E+G + + S + G QY Sbjct: 480 REGIAYGSPEALDFTNLYFYTITWHAVHTSMRLARERGKTFAGFAQSRYASGDYFTQYLQ 539 Query: 569 DMW--------------NVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNN 614 D W +T W L++ + +YGI N L A PT S + I Sbjct: 540 DDWQPKTAKVRALFARSGITLPTREMWLKLRDDVMRYGIYNQNLQAVPPTGSISYINHAT 599 Query: 615 ESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPD 674 SI P + I R+ + T R + P + + Sbjct: 600 SSIHPIVAKIEIRK--------------EGKTGRVYY----------------PAPFMTN 629 Query: 675 DLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGK-LTSMHFYGWKQGLK 733 + +Y+ ++I + ++ AE +DQ SL + + + + Y W++G+K Sbjct: 630 ENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIK 689 Query: 734 TGMYYLRTRPAA 745 + +YY+R R A Sbjct: 690 S-LYYIRLRQLA 700 >6DQW-A nrPDB Length = 585 Score = 571 bits (1472), Expect = e-163, Method: Composition-based stats. Identities = 173/612 (28%), Positives = 278/612 (45%), Gaps = 92/612 (15%) Query: 149 KTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIE--TYNLLSERWFTHASPTLF 206 + L R YLLK E + + R+ + ++ ++ W + +SP Sbjct: 50 QILNRGYLLK-----GETVEGAIDRICTAAARRLYKPELKESFVEMIERGWMSISSPVWA 104 Query: 207 NAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTN 266 N GT R SCF + + D IEGI L + + +K GG +R GS + N Sbjct: 105 NMGTERGLPISCFNVHVP-DKIEGITHKLGEVIMQTKIGGGTSGYFGELRERGSAVTD-N 162 Query: 267 GNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRAR 326 G S+G V +++++ + QGG +R GAFA YL+ H DI EFL +K + Sbjct: 163 GKSSGAVSFMKLFDTAMDTISQGGVRR-GAFAAYLDIDHPDIEEFLKIKSI----GNPIQ 217 Query: 327 DLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKA 386 +LF + +PD +M+ + + Sbjct: 218 NLFTGICVPDYWMQEM-------------------------------------IDGDADK 240 Query: 387 QQLWYAIIESQTETGTPYMLYKDSCNRKSNQ----QNLGTIKCSNLCTEIVEYTSKDEVA 442 +Q+W ++ES+ + G PY+ + D+ N+ Q QNL I SNLC+EI+ ++ DE Sbjct: 241 RQIWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDESF 299 Query: 443 VCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIG 502 +C L+S+ L +Y + T K V++ + + NYY + A KRHR +G Sbjct: 300 ICCLSSMNLELYEEWKDTEAVKLAIFFLDAVLQEFIEKTEGNYY-LSAANKFAKRHRALG 358 Query: 503 IGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVS 562 +GV G PFE EA++ +IF+ I A +AS +LA+ G E +G Sbjct: 359 LGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELARIYGEPELLKG---- 414 Query: 563 KGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNE-SIEPYT 621 YG RN+ +A PT S++ ILG IEP++ Sbjct: 415 ----------------------------YGRRNTTTMAIAPTTSSSAILGQTSPGIEPFS 446 Query: 622 SNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYK 681 SN Y + G F N +L K L E+GL +EE+ I+ GS+Q + ++ K ++K Sbjct: 447 SNYYKAGLSKGNFMRKNKYLKKLLEEKGLDNEEVWRGIMLNGGSVQHMSQLTQQEKDVFK 506 Query: 682 TVWEISQKTVLKMAAERGAFIDQSQSLNIHIA-EPNYGKLTSMHFYGWKQGLKTGMYYLR 740 T EISQ +++ A R F+DQ QSLN++I E + + W+QG+K+ +YY R Sbjct: 507 TFKEISQLEIVQQAGIRQKFVDQGQSLNLNIPAELAIKDVNRLMIEAWQQGVKS-LYYQR 565 Query: 741 TRPAANPIQFTL 752 ++ + + +L Sbjct: 566 SQSVSKELVTSL 577 >6CGM-A nrPDB Length = 700 Score = 566 bits (1458), Expect = e-161, Method: Composition-based stats. Identities = 166/719 (23%), Positives = 313/719 (43%), Gaps = 100/719 (13%) Query: 86 LHKETKKVFSDVMEDLYNYINPHNGKHSP--MVAKSTLDIV------LANKDRLNSAII- 136 + K+ K F E +++Y + +++ K LD + L S Sbjct: 18 IQKDGKFQFDKDKEAVHSYFVDYINQNTVFFHNLKEKLDYLVENQYYEEEFLSLYSFEDI 77 Query: 137 -------YDRDFSY-NYFGFKTLERSYLLKINGK--VAERPQHMLMRVSVGIHKEDIDAA 186 Y + F + ++ Y LK N K + ER + + V++ D + A Sbjct: 78 KEVFKTAYAKKFRFPSFMSAFKFYNDYALKTNDKKKILERYEDRISIVALFFANGDTEKA 137 Query: 187 IETYNLLSERWFTHASPTLFNAG-TNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSA 245 E NL+ + + ++PT NAG R +L SCFLL + +DS+ I + +SK Sbjct: 138 KEYVNLMINQEYQPSTPTFLNAGRKRRGELVSCFLLEV-NDSLNDISRAIDISMQLSKLG 196 Query: 246 GGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWH 305 GG+ + +S +RA G I + G+V ++++ +N RY DQ G +R G+ A YL +H Sbjct: 197 GGVSLNLSKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMG-QRQGSGAAYLNIFH 255 Query: 306 LDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNEC-----PGLD 360 DI +FLD KK + E+ R + L + IPD F++ ++ + P+ +D Sbjct: 256 RDINDFLDTKKISADEDVRVKTLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMD 315 Query: 361 EVWGEEFEKLYASYEKQGRVRK-VVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQN 419 E+ + ++Y + RV+K + ++L + ++E+G PY++++D+ N+ + Sbjct: 316 EM---DMNEMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNH 372 Query: 420 LGTIKCSNLCTEIVE---------YTSKDEVAV---CNLASLALNMYVTSEHTYDFKKLA 467 + +K SNLC+E+++ Y +DE+ + CNL SL + + K + Sbjct: 373 ISKVKFSNLCSEVLQASQVSSYTDYDEEDEIGLDISCNLGSLNILN------VMEHKSIE 426 Query: 468 EVTKVVVRNLNKIIDI-NYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQL 526 + K+ +L + + + P +NK + IG+G L +ES EA+ Sbjct: 427 KTVKLATDSLTHVSETTDIRNAPAVRRANKAMKSIGLGAMNLHGYLAQNGIAYESPEARD 486 Query: 527 LNKQIFETIYYGALEASCDLAKEQG-PYETYEGSPVSKG--ILQYDMWNVTP-------- 575 F + + +++ S ++AKE+G ++ YEGS + G +Y + +P Sbjct: 487 FANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYATGEYFDKYVSTDFSPKYEKIANL 546 Query: 576 ------TDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRV 629 DWK LK +A++G+ +S + PT S + + + S+ P Sbjct: 547 FEGMHIPTTEDWKKLKAFVAEHGMYHSYRLCIAPTGSISYVQSSTASVMP---------- 596 Query: 630 LSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQK 689 +++ + ER + + + +P + + YK +++ Sbjct: 597 -----------IMERIEERTYGNSK----------TYYPMPGLASNNWFFYKEAYDMDMF 635 Query: 690 TVLKMAAERGAFIDQSQSLNIHIAEPNYGK-LTSMHFYGWKQGLKTGMYYLRTRPAANP 747 V+ M A IDQ S + + + + L + Y +G+KT +YY RT+ Sbjct: 636 KVVDMIATIQQHIDQGISFTLFLKDTMTTRDLNRIDLYAHHRGIKT-IYYARTKDTGQD 693 >6DQX-A nrPDB Length = 574 Score = 530 bits (1365), Expect = e-151, Method: Composition-based stats. Identities = 185/605 (30%), Positives = 278/605 (45%), Gaps = 94/605 (15%) Query: 151 LERSYLLKINGKVAERPQHMLMRVSVGIHKEDID-AAIETYNLLSERWFTHASPTLFNAG 209 L+R YLL+ ER + + HK I+ A + Y+ ++ +F+ +SP N G Sbjct: 41 LQRGYLLEGT-TALERIRFIAEHAE---HKLGIEGYADKFYHYMARGYFSLSSPIWSNFG 96 Query: 210 TNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNS 269 +R SCF S DSI I T + ++SK GG IR GS I NG S Sbjct: 97 LDRGLPISCFG-SYIGDSIHEIMVTTAEVGMMSKIGGGTSAYFGDIRPRGSAIK-NNGKS 154 Query: 270 NGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLF 329 +G ++++ + Q G R G FA Y++ H DI E+LD+ Sbjct: 155 DGSFNFSKLFDTVIDVISQ-GTSRKGQFAGYIDIEHGDIDEWLDI--------------- 198 Query: 330 FALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQL 389 E N LM C G D W E K G K +QL Sbjct: 199 -----------HTEGNP-IQLMYYGVCVGHD--WLESM--------KAGDPYK----RQL 232 Query: 390 WYAIIESQTETGTPYMLYKDSCNRKSNQ----QNLGTIKCSNLCTEIVEYTSKDEVAVCN 445 W +++ +TETG PY+ +KD+ N +N+ T+ SNLCTEI+ +S DE VC Sbjct: 233 WAKLLQRKTETGIPYLFFKDNANAGRPDVYKDKNM-TVHASNLCTEIMLPSSNDESFVCC 291 Query: 446 LASLALNMYVTSEHTYDFKKLAEVTKVVVRNL-NKIIDINYYPVPEACLSNKRHRPIGIG 504 L+S+ L + + T + L VV+ K D+ + + A RHR +G+G Sbjct: 292 LSSMNLLYFDEWKDTEAPEVLTYFLDVVMSEFIEKSKDMPF--LDRAHRFATRHRALGLG 349 Query: 505 VQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKG 564 V G F+S +A N IF+T+ L+AS +LAK G E +G Sbjct: 350 VLGWHSYLQANNIAFDSFQAMQKNNLIFKTLQEKTLKASQELAKRFGEPEILKG------ 403 Query: 565 ILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGN-NESIEPYTSN 623 YG RN+ L++ PT S++ ILG+ + S+EP+ SN Sbjct: 404 --------------------------YGRRNTTLMSIAPTKSSSFILGSVSPSVEPFKSN 437 Query: 624 IYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTV 683 Y + + + NP L K L E+GL EE+ I+ +GS+Q + ++ D+ K+++KT Sbjct: 438 YYVKDLAKIKTVYKNPFLEKLLQEKGLDTEEIWESILHNDGSVQHLEQLTDEEKEVFKTF 497 Query: 684 WEISQKTVLKMAAERGAFIDQSQSLNI--HIAEPNYGKLTSMHFYGWKQGLKTGMYYLRT 741 EISQ +V++ AA+R +IDQ QS+NI H A P L ++ + GLK+ +YY + Sbjct: 498 SEISQLSVIQQAAQRQKYIDQGQSINIMVHPATPAR-DLNQLYLTAEELGLKS-IYYQYS 555 Query: 742 RPAAN 746 AA Sbjct: 556 MSAAQ 560 >3O0O-A nrPDB Length = 644 Score = 488 bits (1257), Expect = e-138, Method: Composition-based stats. Identities = 156/616 (25%), Positives = 269/616 (43%), Gaps = 87/616 (14%) Query: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTN-------RP-------------------- 213 + + +L R F SPTLFNAG +P Sbjct: 70 RIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLH 129 Query: 214 QLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLV 273 LS+CF++ + DSIE I++ +K+ ALI+K GG+G S +R GS++AGT+G ++G V Sbjct: 130 MLSACFVVPV-GDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPV 188 Query: 274 PMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALW 333 + V+N+ V QG +R GA L H DI EF+D KK E A FF L Sbjct: 189 SFMHVFNSAISVVKQGSRRR-GALMGILNINHPDIEEFIDAKKENTGE---AVLNFFNL- 243 Query: 334 IPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAI 393 S+ P + + +++ E+ E L S+ + +RK VK ++L+ I Sbjct: 244 ---------------SVGFPMDKKEILKLYEEDGE-LELSHPRS-TIRKKVKIRELFRKI 286 Query: 394 IESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNM 453 + ++G P + + N+ I +N C EI + CNL S+ + Sbjct: 287 ATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEI----GLSDYEACNLGSIDVAK 342 Query: 454 YVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFI 513 + + D + L E+ ++ VR L+ +ID+N +P+ + + K R +G+G+ G AD Sbjct: 343 FYNNGFV-DLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLY 401 Query: 514 LMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGS---------PVSKG 564 + P+ S EA+ + I A S +L KE+G + E S P + G Sbjct: 402 KLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMG 461 Query: 565 ILQYDMWNVTPTDLWDWKVLKE--KIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTS 622 + YD ++E K+ K RN L+ PT S + I + +EP Sbjct: 462 MSNYD------------DEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFL 509 Query: 623 NIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQI---IACNGSIQSIPEIPDDLKQL 679 YTR V + E P L + R + E+ +I + GS++ IP++P+ +K++ Sbjct: 510 LAYTRFV-TKEDGTKEPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKV 568 Query: 680 YKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNY-GKLTSMHFYGWKQGLKTGMYY 738 + +I L M ++D + S I++ + + +++ + ++ Y Sbjct: 569 FVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVY 628 Query: 739 ----LRTRPAANPIQF 750 L+T+ ++ Sbjct: 629 RDGSLQTQVLTKALKT 644 >1L1L-A nrPDB Length = 739 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 82/532 (15%), Positives = 166/532 (31%), Gaps = 85/532 (15%) Query: 250 VAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIF 309 + +S IR G+ I G G ++G +P++ + + ++ NK G DI Sbjct: 252 LDLSDIRPYGAEIHGFGGTASGPMPLISMLLDVNEVLN---NKAGGRLTA---VDAADIC 305 Query: 310 EFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEK 369 + G V + + +L N+ + ++ + Sbjct: 306 NLIGKAVVAGN---------------------VRRSAELALGS-NDDQDFISMKQDQEKL 343 Query: 370 LYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQN------LGTI 423 ++ + V V A + I E G P ++ D + G + Sbjct: 344 MHHRWASNNSV-AVDSAFSGYQPIAAGIRENGEPGIVNLDLSKNYGRIVDGYQAGIDGDV 402 Query: 424 KCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDI 483 + +N C EI + CNL + + E +D L EV + R ++ Sbjct: 403 EGTNPCGEISLANGEP----CNL--FEVFPLIAEEQGWD---LQEVFALAARYAKRVT-F 452 Query: 484 NYYPVPEACLSNKRHRPIGIGVQGLADA-FILMRYPFESAEAQLLNKQIFETIYYGALEA 542 + Y + +++R IGI + G+ D + + + + E I Sbjct: 453 SPYDWEISREIIQKNRRIGISMSGIQDWLLTRLGNRVVTGFKDDFDPETHEAI------- 505 Query: 543 SCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPM 602 + K ++ D K I+++ Sbjct: 506 --------------KVPVYDKRAIKMVDQLYKAVVKADQDYSKTLGCNESIKHTT---VK 548 Query: 603 PTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIAC 662 P+ + A++ G +E + + +R+ FQ +P LL L G E I Sbjct: 549 PSGTVAKLAGASEGMHFHYGAYLIQRI---RFQDSDP-LLPALKACGYRTEA---DIYTE 601 Query: 663 NGSI--QSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGA-FIDQSQSLNIHIAEPNYGK 719 N + I + D + + +S A + D + S I + + Sbjct: 602 NTTCVEFPIKAVGADNPN-FASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQDSEGDQ 660 Query: 720 LTSMHFYGWKQGLKTGM---YYLRTRPAANPIQFTLNKEKLKDKEKVSKEEE 768 + S+ ++ K+ Y+ + A + + +E EE Sbjct: 661 VESL-LRQYRFITKSTSLLPYFGGSLQQAPKEPIDKETYEKRSQEITGNVEE 711 >2GAI-A nrPDB Length = 633 Score = 36.4 bits (82), Expect = 0.048, Method: Composition-based stats. Identities = 23/142 (16%), Positives = 42/142 (29%), Gaps = 26/142 (18%) Query: 40 TMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNL-----------HK 88 TM + Q LY GV T + T +T+ DYA AR ++ + + Sbjct: 265 TMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERR 324 Query: 89 ETKKVFSDVMEDLYNYIN----PHNGKHSPMVAKSTLDIVLANK-----------DRLNS 133 ++ D E + GK+ K +++ + Sbjct: 325 KSNAKIQDAHEAIRPTNVFMTPEEAGKYLNSDQKKLYELIWKRFLASQMKPSQYEETRFV 384 Query: 134 AIIYDRDFSYNYFGFKTLERSY 155 D + + K + Y Sbjct: 385 LRTKDGKYRFKGTVLKKIFDGY 406 >4HZC-A nrPDB Length = 281 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 59/146 (40%), Gaps = 10/146 (6%) Query: 607 TAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSI 666 ++++ + ++P +I R + E +P L L L ++ ++ Sbjct: 6 SSKVNAGLDQVDPIWHSI---RAEAEEATRNDPVLGAFLYATILNQPSLEEAVMHRIAER 62 Query: 667 QSIPEIPDD-LKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGK---LTS 722 P++ D L+Q + T+ E + + + + A D+ + + + Y K Sbjct: 63 LGHPDVSADILRQTFDTMLEANPEWSHVLRVDIQAVYDRDPAYSRFMDPVLYLKGFHAIQ 122 Query: 723 MHFYG---WKQGLKTGMYYLRTRPAA 745 H +KQG K YYL++R ++ Sbjct: 123 THRLAHWLYKQGRKDFAYYLQSRSSS 148 >3U27-C nrPDB Length = 220 Score = 33.7 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 39/131 (29%) Query: 88 KETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFG 147 K ++ L + +P KS L + + + I + D S YF Sbjct: 69 KSFYGGAANANTKLAGEVIGILSGPTPAEVKSGLAAAVDFIENEAAFISANDDDSIAYFA 128 Query: 148 FKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFN 207 L + E + +D A++ ++ ++ S T F Sbjct: 129 HCISRTGTYLSKTAGIPEGESLAYLIAPPLEAMYALDVALKAADVRLVAFYGPPSETNFG 188 Query: 208 AGTNRPQLSSC 218 G S+C Sbjct: 189 GGLLTGSQSAC 199 >6AF0-A nrPDB Length = 939 Score = 32.9 bits (73), Expect = 0.52, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 50/154 (32%), Gaps = 24/154 (15%) Query: 48 YSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYN---- 103 Y G ++D A ET L ++H DY R+A L + K D + LY Sbjct: 590 YEG----DIDK-AIETYEQLLSRHSDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQENPS 644 Query: 104 --YINPHNGKHSPMVAKSTLDIVLANKDRL----NSAIIYDRDFSYNYFGFKTLERSYLL 157 + G V +A ++ YD+ Y G L +L+ Sbjct: 645 DLEVRGLYGWFLSKVNSKKRPANIAEDPEQRHYKHTLQSYDKHDRYALVGMGNL---HLM 701 Query: 158 KINGKVAERPQHMLMRVSVGIHKEDIDAAIETYN 191 E Q R + + A+E ++ Sbjct: 702 AAREMRRETEQDRQKRSAA------YNRAVEFFD 729 >2RG9-A nrPDB Length = 249 Score = 32.1 bits (71), Expect = 0.95, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 31/97 (31%), Gaps = 1/97 (1%) Query: 191 NLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALI-SKSAGGIG 249 + +S F++ P L + + S L+ + ++ + I + L G Sbjct: 26 DFVSSGSFSNNIPLLRQSTIPVSEASRFVLVELTNEGGDSITAAIDVTNLYVVAYQAGQQ 85 Query: 250 VAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYV 286 G+ G + +P Y + RY Sbjct: 86 SYFLKDAPRGAETQDFTGTTRSSLPFNGSYPDLERYA 122 >3EZK-A nrPDB Length = 577 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 19/152 (12%), Positives = 54/152 (35%), Gaps = 9/152 (5%) Query: 298 AIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECP 357 A + H + E + + + W P+ F + ++ + ++ P Sbjct: 17 AGKILIKHPSLAE-----RKDEDGIHWIKSQWDGKWYPEKFSDYLRLHKIVKIPNNSDKP 71 Query: 358 GLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLY--KDSCNRKS 415 L + + ++ K + Y + K + W + + + ++Y + C Sbjct: 72 ELFQTYKDKNNKR-SRYMGLPNL-KRANIKTQWTREMVEEWKKCRDDIVYFAETYCAITH 129 Query: 416 NQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLA 447 + ++ + ++++ S + VCNL+ Sbjct: 130 IDYGVIKVQLRDYQRDMLKIMSSKRMTVCNLS 161 >3CWV-A nrPDB Length = 369 Score = 31.0 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 33/100 (33%), Gaps = 6/100 (6%) Query: 200 HASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATG 259 H P +F+ T C L +D+ + + + + +R Sbjct: 224 HPEPVVFDF-TWDGLRVQCALQWCEDE--DSTLLSFANAVRTVRHGAHVKGVTQALR--- 277 Query: 260 SYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAI 299 +A +G + G P RV V G +R AFA Sbjct: 278 GALAKLSGETRGAFPWARVAQGLTAIVAVSGPRRQMAFAG 317 >2QZU-A nrPDB Length = 491 Score = 31.0 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 42/128 (32%), Gaps = 10/128 (7%) Query: 249 GVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDI 308 G+ ++ + GS + G + + + N + D K G Y+ WHLD Sbjct: 81 GMLMTGMYPIGSKVTGNCNSETAPYGV-ELSQNARCWSDVL--KDQGYNMGYIGKWHLDA 137 Query: 309 --FEFLDLKKNTGKEEQR-----ARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDE 361 ++D N GK R F WI W+ P + Sbjct: 138 PYKPYVDTYNNRGKVAWNEWCPPERRHGFDHWIAYGTYDYHLKPMYWNTTAPRDSFYYVN 197 Query: 362 VWGEEFEK 369 WG E+E Sbjct: 198 QWGPEYEA 205 >5XVU-A nrPDB Length = 332 Score = 29.8 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 47/132 (35%), Gaps = 16/132 (12%) Query: 3 VIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVT---------- 52 ++ RD + +M D +I+ + +GL + + ++V Y G Sbjct: 146 IMHRDVKPHNIMIDHENRQIRLISWGLAEFYHPGQEYNVRVASRYYKGPELLIDLQLYDY 205 Query: 53 TVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKH 112 ++++ +L A + K P L K KV EDL+ Y+ +N K Sbjct: 206 SLDIWSLGCMLAGMIFKKEP---FFCGHDNYDQLVKIA-KVLG--TEDLHAYLKKYNIKL 259 Query: 113 SPMVAKSTLDIV 124 P + Sbjct: 260 KPHYLNILGEYE 271 >5K8D-B nrPDB Length = 865 Score = 29.8 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 25/74 (33%), Gaps = 8/74 (10%) Query: 302 EPWHLDIF--------EFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCP 353 W + +F K TG Q + L ++++ + + + W+L Sbjct: 524 NAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ 583 Query: 354 NECPGLDEVWGEEF 367 N + + + F Sbjct: 584 NGKVKVFQGNQDSF 597 >4BDV-B nrPDB Length = 685 Score = 29.4 bits (64), Expect = 5.5, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 25/74 (33%), Gaps = 8/74 (10%) Query: 302 EPWHLDIF--------EFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCP 353 W + +F K TG Q + L ++++ + + + W+L Sbjct: 570 NAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ 629 Query: 354 NECPGLDEVWGEEF 367 N + + + F Sbjct: 630 NGKVKVFQGNQDSF 643 >2R7E-B nrPDB Length = 770 Score = 29.4 bits (64), Expect = 5.8, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 25/74 (33%), Gaps = 8/74 (10%) Query: 302 EPWHLDIF--------EFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCP 353 W + +F K TG Q + L ++++ + + + W+L Sbjct: 655 NAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ 714 Query: 354 NECPGLDEVWGEEF 367 N + + + F Sbjct: 715 NGKVKVFQGNQDSF 728 >6DQU-A nrPDB Length = 530 Score = 29.0 bits (63), Expect = 7.9, Method: Composition-based stats. Identities = 27/196 (13%), Positives = 54/196 (27%), Gaps = 29/196 (14%) Query: 28 GLNMDFVDPAQIT----MKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAV 83 G DP + V L G+ T + + AA PD+ Sbjct: 21 GAEPQSFDPHKTEGVPESNVAYQLLEGLVTSDSEGKLQPGAAESWENTPDFKTWT----- 75 Query: 84 SNLHKETKKVFSDVMEDLYNYI-----------NPHNGKHSPMV-AKSTLDIVLANKDRL 131 +L K+ K D + ++++ + + ++ DI+ K Sbjct: 76 FHLRKDAKWSNGDPVTA-HDFVFAWRRLVDPATAAPYASYLSYLQVENAQDIIDGKKKPA 134 Query: 132 NSAIIYDRDFSYNY-------FGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDID 184 + D+++ + LL + KV E+ ++ + Sbjct: 135 ELGVEAKDDYTFVVHATNPVPYAVSLTTHQSLLPLPQKVVEKLGDAWVKKENYVGNGAYK 194 Query: 185 AAIETYNLLSERWFTH 200 A N E Sbjct: 195 LANHIINEKIEFERNP 210 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.120 0.289 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,983,651 Number of Sequences: 36641 Number of extensions: 923237 Number of successful extensions: 2832 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 2669 Number of HSP's gapped (non-prelim): 60 length of query: 792 length of database: 10,336,785 effective HSP length: 105 effective length of query: 687 effective length of database: 6,489,480 effective search space: 4458272760 effective search space used: 4458272760 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)