BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23847 (535 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1DPE-A nrPDB 1058 0.0 5F1Q-A nrPDB 976 0.0 3M8U-A nrPDB 563 e-161 3TPA-A nrPDB 531 e-151 4QFK-H nrPDB 449 e-126 5U4O-A nrPDB 226 1e-59 1UQW-A nrPDB 198 6e-51 3MW0-A nrPDB 154 1e-37 6HLX-A nrPDB 153 2e-37 4OEU-A nrPDB 151 6e-37 1XOC-A nrPDB 143 2e-34 4GL8-A nrPDB 141 6e-34 5ISU-A nrPDB 135 4e-32 5YH8-A nrPDB 130 2e-30 4OER-A nrPDB 127 1e-29 1OLA-A nrPDB 118 6e-27 5ZA4-A nrPDB 118 7e-27 3TCF-A nrPDB 117 9e-27 4ZE8-A nrPDB 117 2e-26 2Z23-A nrPDB 113 3e-25 4WED-A nrPDB 97 1e-20 3O9P-A nrPDB 96 4e-20 4PFU-A nrPDB 92 4e-19 3T66-A nrPDB 92 5e-19 6DQU-A nrPDB 92 5e-19 4PFT-A nrPDB 92 7e-19 3ZS6-A nrPDB 84 2e-16 4XKN-A nrPDB 79 5e-15 4OFL-A nrPDB 72 6e-13 5KZT-A nrPDB 70 2e-12 1ZTY-A nrPDB 70 3e-12 2D5W-A nrPDB 66 4e-11 3DRH-A nrPDB 65 7e-11 6EQ0-A nrPDB 64 2e-10 5YQW-A nrPDB 59 4e-09 6NPO-A nrPDB 59 7e-09 2WOP-A nrPDB 58 9e-09 4FAJ-A nrPDB 58 1e-08 5IPW-A nrPDB 57 2e-08 4ONY-A nrPDB 53 3e-07 3I5O-A nrPDB 50 2e-06 5ICQ-A nrPDB 43 4e-04 3WE0-A nrPDB 32 0.95 2CWD-A nrPDB 30 2.5 1V8F-A nrPDB 30 3.9 2XCU-A nrPDB 29 4.7 5AFO-A nrPDB 29 6.4 5WQW-A nrPDB 28 9.0 >1DPE-A nrPDB Length = 507 Score = 1058 bits (2735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/507 (99%), Positives = 505/507 (99%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 KTLVYCSEGSPEGFNPQLF SGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG Sbjct: 1 KTLVYCSEGSPEGFNPQLFISGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 60 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 148 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL Sbjct: 61 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 120 Query: 149 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 208 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI Sbjct: 121 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 180 Query: 209 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 268 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP Sbjct: 181 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 240 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ Sbjct: 241 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 300 Query: 329 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 388 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN Sbjct: 301 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 360 Query: 389 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLF 448 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFAT F Sbjct: 361 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATEF 420 Query: 449 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV Sbjct: 421 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 480 Query: 509 FEPVRKEVKGYVVDPLGKHHFENVSIE 535 FEPVRKEVKGYVVDPLGKHHFENVSIE Sbjct: 481 FEPVRKEVKGYVVDPLGKHHFENVSIE 507 >5F1Q-A nrPDB Length = 543 Score = 976 bits (2522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/535 (84%), Positives = 504/535 (94%) Query: 1 MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPL 60 M ISL+++G+LK G+ LVA+T+AASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVP+ Sbjct: 1 MTISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPI 60 Query: 61 YNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVF 120 YNRLVEFKIGTTE+ P LAE+WEVSEDGKTYTF+LRKGVKW DNK+FKPTR+ NADDV++ Sbjct: 61 YNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIY 120 Query: 121 SFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAM 180 SF RQK+ +NPYHKVSGGSYEYF+GMG+ +LI+ V KVDDNTV+F LTRPE+PFLADLAM Sbjct: 121 SFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAM 180 Query: 181 DFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQID 240 DFASILS EYAD M+KAGTPEK+DLNPIGTGPFQLQQYQKDSRI YKAF G+WGTKP+ID Sbjct: 181 DFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID 240 Query: 241 TLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQ 300 LVFSITPDASVRYAKLQKNECQ+MPYPNPADIARMK+DK+INLME PGLNVGYLS+N++ Sbjct: 241 RLVFSITPDASVRYAKLQKNECQIMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIE 300 Query: 301 KKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAK 360 KKPLD++KVRQALT AVNKDAII AVYQGAG +AKNLIPPTMWGYNDDV+DY YDP KAK Sbjct: 301 KKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAK 360 Query: 361 ALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKR 420 LLKEAGL GFSIDLWAMPVQRPYNPNARRMAEMIQ+DWAK+GV+AKIVTYEWGEYLKR Sbjct: 361 ELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKR 420 Query: 421 AKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDH 480 AKDGEH+TVMMGWTGDNGDPDNFFATLFSC A++QGSNYSKWCYKPFEDLIQPARA DH Sbjct: 421 AKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH 480 Query: 481 NKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 +KRV LYKQAQVVM++QAPALIIAHSTV+EPVRKEVKGYVVDPLGKHHF+NVS++ Sbjct: 481 DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD 535 >3M8U-A nrPDB Length = 522 Score = 563 bits (1451), Expect = e-161, Method: Compositional matrix adjust. Identities = 265/497 (53%), Positives = 342/497 (68%), Gaps = 1/497 (0%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 KT + C SP GF+P L G +Y+ASS +YNRLVEFK G+T++ P LAE W VS+DG Sbjct: 3 KTFINCVSRSPTGFSPALVMDGISYNASSQQVYNRLVEFKRGSTDIEPALAESWTVSDDG 62 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 148 TYTF+LRKGVK+H NKEF P+R+ NADDVVFSF RQ + +PYH VS +Y YF+ M Sbjct: 63 LTYTFNLRKGVKFHSNKEFTPSRDFNADDVVFSFQRQLDPNHPYHNVSKATYPYFKAMKF 122 Query: 149 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 208 L+ V+KVD +TV+ L R +A FLA L MDF SI S EYAD M+ AG PE +D PI Sbjct: 123 STLLKSVEKVDMHTVKITLNRQDATFLASLGMDFISIYSAEYADKMLAAGKPETIDTTPI 182 Query: 209 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 268 GTGPF YQ D + RY A YW K ID L+F I PDA+ RYAKLQ C ++ +P Sbjct: 183 GTGPFLFAGYQVDQKSRYLAHKEYWKGKADIDRLIFEIVPDATARYAKLQAGACDLIDFP 242 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 N AD+ +MK D +NL GLN+ Y+++N +K P D+VKVRQAL YAV+K+AII AVY+ Sbjct: 243 NAADLEKMKTDPKVNLHSQSGLNIAYIAFNTEKAPFDNVKVRQALNYAVDKNAIIDAVYR 302 Query: 329 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 388 GAGV+AKN +PPT+WGYN+++ Y Y PEKAK LLKEAG E GF D+W PV R NPN Sbjct: 303 GAGVAAKNPLPPTIWGYNNEITGYEYSPEKAKQLLKEAGFENGFETDIWVQPVVRASNPN 362 Query: 389 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLF 448 RRMAE++Q+DW KVGV++K+V+YEWG+Y+KR K GE GW+GDNGDPDNF + LF Sbjct: 363 PRRMAELVQSDWEKVGVKSKLVSYEWGDYIKRTKAGELTAGTYGWSGDNGDPDNFLSPLF 422 Query: 449 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 + + SNY+++ + L+ A D +R ++Y+QAQV++ +QAP + +AHS Sbjct: 423 G-SENVGNSNYARFKNPELDALLHKAVGLSDKAERAKIYEQAQVLLKEQAPWINVAHSIN 481 Query: 509 FEPVRKEVKGYVVDPLG 525 F P K V+ Y P G Sbjct: 482 FAPTSKRVQDYKQSPFG 498 >3TPA-A nrPDB Length = 521 Score = 531 bits (1368), Expect = e-151, Method: Compositional matrix adjust. Identities = 260/511 (50%), Positives = 332/511 (64%), Gaps = 1/511 (0%) Query: 25 SVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEV 84 S TLV C +P +P + ++ASS +YNRLVEFK G EV PGLAE+WE+ Sbjct: 4 SAPTNTLVNCIATAPMKLSPAITNDANDFNASSQQVYNRLVEFKAGKIEVEPGLAERWEI 63 Query: 85 SEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFE 144 SEDG YTF+LR+ VK+H NK F PTR LNADDVVFSF RQ + +PYH VS G+Y YF Sbjct: 64 SEDGLVYTFYLRQNVKFHSNKTFSPTRPLNADDVVFSFQRQADKNHPYHNVSAGTYFYFN 123 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 M LP ++ V+KVDD TV+ L +P PF+ +AMDF SI SKEYAD ++ G PE LD Sbjct: 124 WMNLPSILKSVEKVDDYTVKITLNKPNTPFITTVAMDFLSIYSKEYADQLLAQGKPETLD 183 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQV 264 PIGTGPF Q Q D +RY A YW K I+ L+FSITPDA RYAKL+ EC V Sbjct: 184 QQPIGTGPFIFQTNQTDHAVRYTANVDYWKGKADIERLIFSITPDAGTRYAKLKAGECDV 243 Query: 265 MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIK 324 + +PN +DIA+MK+D INL+E GLN+ Y+ N K L++VKVRQAL +A +K AI+ Sbjct: 244 IDFPNISDIAQMKKDPQINLLEREGLNLAYIGLNTTKPELNNVKVRQALHHATDKKAIVD 303 Query: 325 AVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRP 384 AVYQG G A N P + GYN + Y ++ EKAKALL EAG GF ++W PV RP Sbjct: 304 AVYQGGGTVATNPFPDAVLGYNPHLPQYEFNLEKAKALLAEAGYPNGFETEIWVQPVVRP 363 Query: 385 YNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFF 444 NPN RR AE+IQADWAK+GV+AK+VT+EW ++ KR ++GE GWT NGDPDNF Sbjct: 364 SNPNPRRTAEIIQADWAKIGVKAKLVTHEWADFNKRTREGEFAAGTYGWTSRNGDPDNFL 423 Query: 445 ATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIA 504 LFS A+ G+NYS+W + FE L+ A D R +LY+QA + +P + A Sbjct: 424 FPLFS-QANIPGTNYSRWTDEKFEALLASAAQIQDTQTRAKLYQQAVEIFQQNSPIIPFA 482 Query: 505 HSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 HS + P+ K V+G+V +P G F VS++ Sbjct: 483 HSINYVPLNKRVQGFVQNPFGYTAFYGVSLK 513 >4QFK-H nrPDB Length = 541 Score = 449 bits (1156), Expect = e-126, Method: Compositional matrix adjust. Identities = 215/502 (42%), Positives = 315/502 (62%), Gaps = 2/502 (0%) Query: 31 LVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKT 90 LVYC+E +P FNPQ+ T+G+T D + LY+RL+ T E LA W++S+DGK+ Sbjct: 31 LVYCAEANPVSFNPQVTTTGSTIDIIANQLYDRLISIDPVTAEFKSELATDWKISKDGKS 90 Query: 91 YTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPE 150 TF LRKGVK+H F PTRE NADDV+F+F R + NPYH V +Y YF+ +G+ + Sbjct: 91 VTFTLRKGVKFHTTAYFTPTREFNADDVIFTFSRLFDVYNPYHFVGDANYPYFQSVGIDQ 150 Query: 151 LISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKL-DLNPIG 209 LI ++ +V D+ V+F L E+ FLA++A DFA +LSKEYA A+ KA E L D P+G Sbjct: 151 LIRKIVRVSDHQVRFELFNAESSFLANMATDFAVVLSKEYAMAL-KANNQENLFDQYPVG 209 Query: 210 TGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPN 269 TGP+ ++Y++D +R+ YW + ++ LV+ ITP+ + R AK+ EC V +P+ Sbjct: 210 TGPYIYKEYRRDHLVRFYKNADYWKHEVALEQLVYDITPNGTTRIAKILTKECDVTAHPS 269 Query: 270 PADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQG 329 A ++ + Q IN+ LN+GY ++N ++ P D++KVRQAL +A++ + I++AVY G Sbjct: 270 SAQLSILAQRDDINVERETNLNIGYWAFNTERPPFDNLKVRQALVHAIDIEKIMQAVYYG 329 Query: 330 AGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNA 389 G+ A++++PPT W + +DP+ AK LL EAG EKGF + +WAMPV R YNPNA Sbjct: 330 NGLRARSILPPTSWAFEPQKNMPIFDPQLAKKLLTEAGYEKGFDMSIWAMPVSRIYNPNA 389 Query: 390 RRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFS 449 R+MAE++Q+D K+GV IV YEW +++R + H +V++GW D DPDNFF+ L S Sbjct: 390 RKMAELMQSDLRKIGVNVNIVEYEWNTFIQRIGEHRHDSVLLGWAADTPDPDNFFSPLLS 449 Query: 450 CAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVF 509 C A+ G N + WC F+ L+ A T D N R + Y AQ ++ +Q P IAH F Sbjct: 450 CTATFSGKNPANWCNPEFDLLLTKALDTTDLNLRKQYYDAAQSMIIEQLPLYPIAHGMRF 509 Query: 510 EPVRKEVKGYVVDPLGKHHFEN 531 + +V+G + P G N Sbjct: 510 QASSADVEGITLGPFGAISLAN 531 >5U4O-A nrPDB Length = 521 Score = 226 bits (577), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 157/549 (28%), Positives = 258/549 (46%), Gaps = 51/549 (9%) Query: 7 KSGMLKLGLSLVAMTV---AASVQAKT--LVYCSEGSPEG-------------FNPQLFT 48 K G++ ++++ ++V S AKT S+G+ EG +P T Sbjct: 4 KRGLVSCFIAILCLSVFLAGCSSNAKTGNEGSGSKGTKEGGVLTIARLSDADNLDPHFIT 63 Query: 49 SGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFK 108 + + +Y LV+ + + P LA++W+ +D + F L++GV + D F Sbjct: 64 NIPSASVVYHKVYENLVQ-RDKNMDFKPMLAKEWKQIDD-LNWEFKLQQGVTFQDGAPF- 120 Query: 109 PTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLT 168 NA+ V +F+R + + ++ + + +I E+K +D+ TVQF+L Sbjct: 121 -----NAEAVKKNFERVLDPKVGSNRAT-----------VYSMIQEIKVIDEYTVQFILK 164 Query: 169 RPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKA 228 P +P L+ A + SILS + D K L +P+GTGP+ + ++ IR + Sbjct: 165 YPYSPLLSIFASNEGSILSPKAIDEKGKG-----LAQHPVGTGPYTFKSWKPGEEIRLEK 219 Query: 229 FDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMP 288 YWG K ++D +VF + P+ + R ++ +E + ++ R+K S+ L+E Sbjct: 220 NKNYWGEKAKVDEVVFKVVPEDATRIGMIETSEAHIAENLPVTEVERVKNSPSMELIENE 279 Query: 289 GLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDD 348 GL V Y+ +NV+KKP D+ VRQA+ +A+ I+K VY G +++ P ++GY D Sbjct: 280 GLGVEYIGFNVEKKPFDNPLVRQAIAHAIETKGILKGVYNNVGTEINSVMTPKVFGYTKD 339 Query: 349 VQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMA--EMIQADWAKVGVQ 406 V+ Y YD AK LL +AG GF +W N + RMA E+IQ+ +GV Sbjct: 340 VKGYKYDINTAKKLLADAGYPNGFKTTIWT-------NDSKVRMALVEVIQSQLKGIGVD 392 Query: 407 AKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKP 466 +I E+G +L EH + GW GD D LF ++ N + Sbjct: 393 VEIKVMEYGAFLAATNKSEHAMFVGGWGNATGDGDYNQYNLFHSSSHGATGNQFFYSNPE 452 Query: 467 FEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGK 526 + LI+ AR D KR ELYKQ Q + A + I K +KG+ +DP G Sbjct: 453 VDKLIEEARKEKDETKRKELYKQLQEIELKDALLVPIRGINHIAATTKNIKGFWIDPSGY 512 Query: 527 HHFENVSIE 535 E V ++ Sbjct: 513 LRLEGVELQ 521 >1UQW-A nrPDB Length = 509 Score = 198 bits (503), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 134/466 (28%), Positives = 236/466 (50%), Gaps = 36/466 (7%) Query: 78 LAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSG 137 LAE + VS+DG TYT LR+G+K+ D +F NA V + DR + N Sbjct: 72 LAESYTVSDDGITYTVKLREGIKFQDGTDF------NAAAVKANLDRASDPAN------- 118 Query: 138 GSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKA 197 + + L + I++ + +D TV+ L +P + F+ LA +++S A+ K Sbjct: 119 ----HLKRHNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAHPATAMISPA---ALEKY 171 Query: 198 GTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-PQIDTLVFSITPDASVRYAK 256 G +++ P+GTGP++L + + ++ K F GYW P++D++ + D + R A Sbjct: 172 G--KEIGFYPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAM 229 Query: 257 LQKNECQVMPYPNPADIARM-KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTY 315 LQ E Q +P P + A + +++K+I LM P + Y+S NV +KP D+ KVR+AL Y Sbjct: 230 LQTGEAQ-FAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNY 288 Query: 316 AVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSID 375 A+N+ A++K + G A ++PP++ Y + + YDP KA+ LLKEAG GFS Sbjct: 289 AINRPALVKVAFAGYATPATGVVPPSI-AYAQSYKPWPYDPVKARELLKEAGYPNGFSTT 347 Query: 376 LWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYL-----KRAKDGEHQTVM 430 LW+ + A+++ + Q A+VG++A++ + G+ K K+ + Sbjct: 348 LWS----SHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFY 403 Query: 431 MGWTGDNGDPDNFFATLFSCAA-SEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQ 489 GW+ G+ D + LF+ N + + K +D + A T+D ++ LYK Sbjct: 404 TGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKA 463 Query: 490 AQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 AQ ++ ++P + + + K + G+ + P FE+ ++ Sbjct: 464 AQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFEDADLQ 509 >3MW0-A nrPDB Length = 502 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 138/510 (27%), Positives = 223/510 (43%), Gaps = 63/510 (12%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKW 101 NP L+T + S V Y LV+++ + VIP LA+ W SEDGKT+TF LR VK+ Sbjct: 17 LNPHLYTPNQMFAQSMV--YEPLVKYQADGS-VIPWLAKSWTHSEDGKTWTFTLRDDVKF 73 Query: 102 HDNKEFKPTRELNADDVVFSFD-RQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD 160 + + F E A++ D RQ++A + L I +VK + Sbjct: 74 SNGEPFD--AEAAAENFRAVLDNRQRHA----------------WLELANQIVDVKALSK 115 Query: 161 NTVQFVLTRPEAPFLADLAMD--FASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY 218 +Q L PFL +LA+ F I ++ + G PIGTGP+ LQ+ Sbjct: 116 TELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKA-----PIGTGPWILQES 170 Query: 219 QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPN----PAD-I 273 + + + + YWG KP I + F++ PD + R + + ++ Y N P D Sbjct: 171 KLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLL-YGNEGLLPLDTF 229 Query: 274 ARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVS 333 AR Q+ + + + L+ N K P +++ VR+AL YAVNK ++I G Sbjct: 230 ARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQV 289 Query: 334 AKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN----- 388 A L P++ N ++ YDP+KAKALL++AG W +P + Sbjct: 290 ADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAG---------WTLPAGKDIREKNGQPL 340 Query: 389 ------------ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGD 436 ++ MAE+IQAD ++G ++ E R +DG + G Sbjct: 341 RIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGA 400 Query: 437 NGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDL-IQPARATDDHNKRVELYKQAQVVMH 495 DP F +++ + ++ + KP D I AT D +R LY+ +H Sbjct: 401 PYDPHAFLSSMRVPSHADFQAQ-QGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLH 459 Query: 496 DQAPALIIAHSTVFEPVRKEVKGYVVDPLG 525 D+A L I++ ++ + E+ P+ Sbjct: 460 DEAVYLPISYISMMVVSKPELGNIPYAPIA 489 >6HLX-A nrPDB Length = 492 Score = 153 bits (386), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 131/463 (28%), Positives = 216/463 (46%), Gaps = 37/463 (7%) Query: 30 TLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGK 89 TL + G P + + GT+ + ++ LV + I ++ P LAE +EVS D K Sbjct: 3 TLYFGLSGEPSTLD-TVVQPGTSGRTVKLAIHRGLVNYGI-DGKISPELAESYEVSPDAK 60 Query: 90 TYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLP 149 +TFHLR+ K+HD + + DV S +R +P K S F Sbjct: 61 EFTFHLRQA-KFHDGTT------VTSADVKASLER---ILDPKGKAS------FRN---- 100 Query: 150 EL--ISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNP 207 EL IS+++ D+ TV+ L+ P + LA+ + I+ A A + + P Sbjct: 101 ELSSISKIETPDEKTVKLTLSTPSVAMIDYLALPESVIVP-----AAWLAKNADNPNAAP 155 Query: 208 IGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKLQKNECQVMP 266 +G GPF+ + + I K FD Y+ KP +D + + D + R L+ + ++ Sbjct: 156 VGAGPFKFAGWTRGREITVKKFDDYYKKGKPDLDEVHYVFYSDENTRVNALKSGDVDIID 215 Query: 267 YPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAV 326 Y D A + + L+ G +G L +N + +P +VRQA+ YAV++ AII Sbjct: 216 YVPAKDAADIAKGPETQLLRNTGPFMG-LQFNTKFEPFSKPEVRQAIAYAVDRSAIINTA 274 Query: 327 YQGAGVSAKNL-IPPTMWGYNDDVQDY-TYDPEKAKALLKEAGLEKGFSIDLWAMPVQRP 384 + G G + IP GY+D +Y ++ EKAKALL +AG GF + L A Q Sbjct: 275 FNGLGSPIFGIAIPKGYMGYSDAKANYFSHHVEKAKALLAKAGYPNGFEVRLLATS-QYS 333 Query: 385 YNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFF 444 + N A IQ++ AK+G++ K+ +W + +A G++ +MG G+ D D Sbjct: 334 FQQNT---AIAIQSELAKIGIKVKLDLPDWASRMAKASTGDYDFTVMGSLGEITDADWLS 390 Query: 445 ATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELY 487 + + +N + + DL+ RAT D +RV++Y Sbjct: 391 NYYYGGDKLVRTNNSPYFNDQQINDLLDKGRATVDKAERVKIY 433 >4OEU-A nrPDB Length = 494 Score = 151 bits (382), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 132/513 (25%), Positives = 237/513 (46%), Gaps = 52/513 (10%) Query: 30 TLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGK 89 TL+ E NP +DA +++ L F + + P LA+ W++S+DG Sbjct: 6 TLIIAVENEIARINP---AYSEDHDAVINLVFSGLTRFDENMS-LKPDLAKSWDISKDGL 61 Query: 90 TYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLP 149 Y LR V WHD +F +ADDV FS + KN +N + Y FE Sbjct: 62 VYDIFLRDDVLWHDGVKF------SADDVKFSIEAFKNPKN-----NSSIYVNFED---- 106 Query: 150 ELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIG 209 I V+ ++ + V+ L +P FL L++ +L K + + + NPIG Sbjct: 107 --IKSVEILNPSHVKITLFKPYPAFLDALSI---GMLPKHLLEN--ENLNTSSFNQNPIG 159 Query: 210 TGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPN 269 TGP++ +++K + +KA + ++ K + L+ D S+ A+L+ + + Sbjct: 160 TGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDA-ALID 218 Query: 270 PADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQG 329 + + K D++ ++ + L +N+ + L D+KVRQAL YAV+K++I+K + Sbjct: 219 VSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHD 278 Query: 330 AGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKG-----------FSIDLWA 378 A + + + W + + + Y YDP+KA+ LL AG +K ++WA Sbjct: 279 YAFVANHPLERS-WANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWA 337 Query: 379 MPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNG 438 M +P +A ++Q+++ K+GV +K+V G + D + ++GW G Sbjct: 338 M----SNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVD----SFLIGW-GSPL 388 Query: 439 DPD----NFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVM 494 DPD F + A +++G N+ + K + +Q AR T + +R + YK + Sbjct: 389 DPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDAL 448 Query: 495 HDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKH 527 ++ P + +A+ K++KG LG H Sbjct: 449 YENPPFIFLAYLDFALVYNKDLKGIKTRTLGHH 481 >1XOC-A nrPDB Length = 520 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 137/519 (26%), Positives = 234/519 (45%), Gaps = 54/519 (10%) Query: 27 QAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTE---VIPGLAEKWE 83 Q LV S G P LF S + D +S + N L F T E V LAE + Sbjct: 20 QGGDLVVGSIGEP-----TLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLAESIK 74 Query: 84 VSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYF 143 + G Y ++KGVK+HD KE L ADDVVF++ Y G +YE Sbjct: 75 ELDGGLAYDVKIKKGVKFHDGKE------LTADDVVFTYSVP--LSKDYKGERGSTYE-- 124 Query: 144 EGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKL 203 ++ V+K D V F L + F + A+D +IL K + A E Sbjct: 125 -------MLKSVEKKGDYEVLFKLKYKDGNFYNN-ALDSTAILPKHILGNVPIADLEEN- 175 Query: 204 DLN---PIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKN 260 + N PIG+GPF+ +++++ I+ +A D Y+ +P +DT+ + + PDA+ A+LQ Sbjct: 176 EFNRKKPIGSGPFKFKEWKQGQYIKLEANDDYFEGRPYLDTVTYKVIPDANAAEAQLQAG 235 Query: 261 ECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKD 320 + P D ++ ++ ++ L+ Y+ +N + + D KVRQALT A++++ Sbjct: 236 DINFFNVP-ATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTALDRE 294 Query: 321 AIIKAVYQGAGVSAKNLIPPTMWGY--NDDVQDYTYDPEKAKALLKEAGLE--------- 369 +I+ V G G A P W Y + DV + Y+ +KAK +L EAG + Sbjct: 295 SIVSQVLDGDGEVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDGILD 354 Query: 370 ---KGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAK--DG 424 K FS L N +A ++Q K+G++ K EW +++ + Sbjct: 355 KDGKKFSFTL----KTNQGNKVREDIAVVVQEQLKKIGIEVKTQIVEWSALVEQMNPPNW 410 Query: 425 EHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRV 484 + ++MGW+ PD + +F + ++G NY + + L++ A++ D + Sbjct: 411 DFDAMVMGWSLSTF-PDQY--DIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQYS 467 Query: 485 ELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDP 523 + Y+Q + + P + + + + ++GY P Sbjct: 468 KEYEQIYQKIAEDQPYTFLYYPNNHMAMPENLEGYKYHP 506 >4GL8-A nrPDB Length = 529 Score = 141 bits (356), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 115/442 (26%), Positives = 208/442 (47%), Gaps = 36/442 (8%) Query: 76 PGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQ--NPYH 133 PGLA+ W++S+DG YTFHLR + W D T E + D++ + N Sbjct: 76 PGLAKSWDISDDGVVYTFHLRDNLVWSDGVSI--TAEGIRKSYLRILDKETGSSFVNMIK 133 Query: 134 KVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLA-MDFASILSKEYAD 192 V + EYF+G + +K +D+ T++ L P+ FL L F + Sbjct: 134 SVIKNAEEYFDGKANESELG-IKALDEKTLEITLKSPKPYFLDMLVHQTFIPVPMHVIEK 192 Query: 193 AMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQI-DTLVFSITPDAS 251 + PE N + +GPF+L+ + ++ + + Y+ +K + D+++F +T ++ Sbjct: 193 YGQRWTDPE----NMVVSGPFKLKSRVLNEKVVLEKNNKYYNSKDVVLDSIIFFVTDNSI 248 Query: 252 VRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLN-VGYLSYNVQKKPLDDVKVR 310 Y +E + P D+ +K K + G+N + S N++ KPLD+VKVR Sbjct: 249 TAYNMYLNDELDAIFKNVPPDL--LKDLKLRDDYYSMGINSTSFYSLNMKVKPLDNVKVR 306 Query: 311 QALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTY-------DPEKAKALL 363 +AL++A+++ + ++V + + + P D DY+Y D E AK LL Sbjct: 307 KALSFAIDRKTLTESVLNDSSIPTRRATP--------DYIDYSYKSNLSLFDAEMAKKLL 358 Query: 364 KEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAK 422 +AG G + L + V+ + + R++AE IQ W K + + ++ EW Y+ Sbjct: 359 ADAGYPNGNNFPL--LKVKYNTSDSQRKIAEFIQNQWKKNLNINVQLENEEWSTYINSRV 416 Query: 423 DGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNK 482 +G ++ + GW+GD DP F + + S YS Y ++L+ + D K Sbjct: 417 NGNYEIIRSGWSGDYADPMTFLSIFQTENTSFSSYGYSNSEY---DELLIKSDNERDIFK 473 Query: 483 RVELYKQAQ-VVMHDQAPALII 503 R E+ K+A+ +++ PA+ + Sbjct: 474 RQEILKKAEAIIIERDFPAVFL 495 >5ISU-A nrPDB Length = 502 Score = 135 bits (340), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 123/481 (25%), Positives = 220/481 (45%), Gaps = 51/481 (10%) Query: 30 TLVYCSEGSPEGFNPQLFTSGTTY---DASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSE 86 +L+ G PE NP + T A PL+ + + P LA+ ++S+ Sbjct: 19 SLIIGVTGDPEVINPNYASDRVTLTIQQAVYAPLFWEV--------DGKPALAKSLDISD 70 Query: 87 DGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFS----FDRQKNAQNPYHKVSGGSYEY 142 D TYT L+ G+ WHD K L ADDVVF+ D ++N+ N + V Sbjct: 71 DNLTYTVKLKDGLTWHDGKP------LTADDVVFTVNSILDTKQNSPNRGNFV------- 117 Query: 143 FEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEK 202 F+ + +V+ VDD TV+F L AP + F I K + + +K Sbjct: 118 FDDKPV-----KVEAVDDTTVKFTLPTV-APAFENTIKTFFPI-PKHIFEGVENIEKSDK 170 Query: 203 LDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNEC 262 + NPIG+GP++ +Y+ + + F+ Y+ KP++D + F IT D + LQ E Sbjct: 171 -NKNPIGSGPYKFVEYKTGEYVSLERFNDYFDGKPKLDKVTFRITKDQNAANLALQNGEI 229 Query: 263 QVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAI 322 + P+D ++++ ++N++ P + Y ++N + L ++RQAL+YA++++ I Sbjct: 230 NLKSI-QPSDRNKVEKASAVNIITYPENRLSYATFNENQPALKSKELRQALSYALDREEI 288 Query: 323 IKAVYQGAGVS--AKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMP 380 I A Y + A + + + D V+ Y D KAK L+KE+G + + ++ + Sbjct: 289 IDAAYGSDEYAKPASSFLTENTKYFTDKVETYDQDIAKAKKLVKESGFDTSQKLTVYYLN 348 Query: 381 VQRPYNPNARRMAEMIQADWAKVGVQAKIVTYE---WGEYLKRAKDGEHQTVMMGWTGDN 437 + + +A +Q + ++GV + + K+ ++ + G+ N Sbjct: 349 NSK----SQESIALYLQQQYKEIGVTLDLKPTDPNALSNITLDRKNADYSIALNGYIMGN 404 Query: 438 GDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQ 497 DPD + + S A NYS + K + L + T D +R E+Y++ Q + D Sbjct: 405 -DPDAYKSLYLSDAP----YNYSNYHNKDLDALWEKGAVTADDKERQEIYEKIQNTIADD 459 Query: 498 A 498 A Sbjct: 460 A 460 >5YH8-A nrPDB Length = 510 Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 138/512 (26%), Positives = 227/512 (44%), Gaps = 55/512 (10%) Query: 20 MTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVI-PGL 78 M + + K L Y + NP ++ G + A S+ +Y LV T + I P L Sbjct: 3 MGLEEKKENKQLTYTTVKDIGDMNPHVY--GGSMSAESM-IYEPLVR---NTKDGIKPLL 56 Query: 79 AEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDR-QKNAQ-NPYHKVS 136 A+KW+VSEDGKTYTFHLR VK+HD F +AD V + D Q+N + + + K+S Sbjct: 57 AKKWDVSEDGKTYTFHLRDDVKFHDGTPF------DADAVKKNIDAVQENKKLHSWLKIS 110 Query: 137 GGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAM--DFASILSKEYADAM 194 LI VK D TV+ L P LA+LAM + + K++ + Sbjct: 111 -------------TLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGT 157 Query: 195 MKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRY 254 K G +K D GTGPF+L +++KD + D YWG K +++ + + P + Sbjct: 158 TKDGV-KKFD----GTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAF 212 Query: 255 AKLQKNECQV-------MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKK--PLD 305 ++K E + + ++K + +N L N KK + Sbjct: 213 LSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVS 272 Query: 306 DVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKE 365 D VRQA+ + VN+D I K + G A L + N D+ YD +KA++LL E Sbjct: 273 DKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDE 332 Query: 366 AGLEKGFSIDL---------WAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGE 416 AG +KG D+ AM + + + + AE +QA++ K+G++ I + Sbjct: 333 AGWKKGKDSDVRQKDGKNLEMAMYYDKG-SSSQKEQAEYLQAEFKKMGIKLNINGETSDK 391 Query: 417 YLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARA 476 +R G++ + G DP + A + E ++ + K + + I A Sbjct: 392 IAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIY-NSIDDAFK 450 Query: 477 TDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 + +R + YK + D+ + I+H ++ Sbjct: 451 IQNGKERSDAYKNILKQIDDEGIFIPISHGSM 482 >4OER-A nrPDB Length = 500 Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 124/491 (25%), Positives = 205/491 (41%), Gaps = 43/491 (8%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKW 101 NP L++ + + V Y LV + T V P LAE WE S+DG++YTF LR+ VK+ Sbjct: 15 LNPHLYSPNQMFAQNMV--YEPLVHYNADGT-VGPWLAESWEASQDGRSYTFKLREDVKF 71 Query: 102 HDNKEFKPTR-ELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD 160 + + F + N D V+ P H E M E++ K Sbjct: 72 SNGEVFDAAAVKANIDTVL--------QNRPRHNW----LELVNQMVSAEVVGPYK---- 115 Query: 161 NTVQFVLTRPEAPFLADLAMD--FASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY 218 V+ L +P P L +L++ F I ++ + GT + + + PIGTGP++L + Sbjct: 116 --VRINLKKPYYPLLQELSLPRPFRFIAPSQFKNG----GTADGI-VAPIGTGPWKLTET 168 Query: 219 QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVM-----PYPNPADI 273 + + D YWG KP + + + PD + R + E ++ P +P Sbjct: 169 KLGEHDVFTRNDSYWGPKPAYEQITVKVIPDPNTRAIAFEAGEIDLIYGTEGPI-SPDTF 227 Query: 274 ARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVS 333 R ++ N L L+ N D+ VR+A+ +AV+KD +I V G Sbjct: 228 ERFQKMGIYNTELSEPLETRVLALNTNHGATKDLAVRKAINHAVDKDTMIATVLYGTQKR 287 Query: 334 AKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDL-----WAMPVQRPY--- 385 A L + N ++ Y +DP A LL EAG S D+ + ++ + Sbjct: 288 ADTLFADNVPYANIGLKPYAFDPALAARLLDEAGWTAKASGDIREKDGQPLAIELCFIGT 347 Query: 386 NPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFA 445 + ++ MAE++QAD KVG+ K+ E R +DG + G DP F + Sbjct: 348 DAISKSMAEIVQADLRKVGIDVKLTGEEESSIYARQRDGRFDMIFNQTWGAPYDPHAFVS 407 Query: 446 TLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAH 505 ++ + ++ + + I + D R LYK +H++A L + Sbjct: 408 SMRVPSHADYQAQLGLPDKAKIDAEIGQVLVSTDETARQALYKDILTRLHEEAVYLPLTS 467 Query: 506 STVFEPVRKEV 516 T + EV Sbjct: 468 VTAMAVAKPEV 478 >1OLA-A nrPDB Length = 517 Score = 118 bits (296), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 128/489 (26%), Positives = 209/489 (42%), Gaps = 62/489 (12%) Query: 76 PGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDR--QKNAQNPYH 133 PG+AEKWE ++D K +TFHLR+ KW D + A D V+S+ R N +PY Sbjct: 58 PGVAEKWE-NKDFKVWTFHLRENAKWSDGTP------VTAHDFVYSWQRLADPNTASPY- 109 Query: 134 KVSGGSY-EYFEGMGLPELISE--------VKKVDDNTVQFVLTRPEAPFLADLAMDFAS 184 SY +Y + ++I+ VK +DD+T + L+ P F L S Sbjct: 110 ----ASYLQYGHIANIDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVS 165 Query: 185 ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVF 244 + K A+ K G N + G ++L+ + + RI + YW + V Sbjct: 166 PVPKS---AVEKFGDKWTQPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVT 222 Query: 245 SITPDASVRYAKLQKNECQVMPYPN-PADI-ARMKQDKSINLMEMPGLNVGYLSYNVQKK 302 + + V ++ M Y N P ++ ++K++ + P L Y N QK Sbjct: 223 YLPISSEVTDVNRYRSGEIDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQKA 282 Query: 303 PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDP------ 356 P +DV+VR AL A+++D I+ V + A + PP Y D + +P Sbjct: 283 PFNDVRVRTALKLALDRDIIVNKVKNQGDLPAYSYTPP----YTDGAK--LVEPEWFKWS 336 Query: 357 -----EKAKALLKEAGL--EKGFSIDLWAMPVQRPYNPN--ARRMAEMIQADWAK-VGVQ 406 E+AK LL EAG +K + DL YN + +++A + + W K +GV Sbjct: 337 QQKRNEEAKKLLAEAGFTADKPLTFDLL-------YNTSDLHKKLAIAVASIWKKNLGVN 389 Query: 407 AKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKP 466 + EW +L G GW D +P +F T+ S+ +N + + Sbjct: 390 VNLENQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTML----SDSSNNTAHYKSPA 445 Query: 467 FEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLG 525 F+ LI D +R ELY +A+ + + + + + V+ V GY DPL Sbjct: 446 FDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLD 505 Query: 526 KHHFENVSI 534 + +N+ I Sbjct: 506 NIYVKNLYI 514 >5ZA4-A nrPDB Length = 488 Score = 118 bits (295), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 97/329 (29%), Positives = 155/329 (47%), Gaps = 28/329 (8%) Query: 41 GFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVK 100 GF+P L +SG + A+++ ++ LV+ T + LA K +D TY LR+G Sbjct: 21 GFDP-LTSSGASSMAANLHIFEGLVDLHPVTRQPYLALAAKEPEQKDDLTYYISLREGAM 79 Query: 101 WHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD 160 +HD + +DVV+SF+R V + +P I+ V +DD Sbjct: 80 FHDGSP------VTTEDVVYSFER----------VLDPAKASLFAQFIP-FIASVTALDD 122 Query: 161 NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQK 220 N V+F L P A F L + I+ K +A A D PIG+GP++ K Sbjct: 123 NVVEFKLKYPFALFKERLTI--IKIVPKHIVEAGQSA-----FDAKPIGSGPYKFVSATK 175 Query: 221 DSRIRYKAFDGYWGTKP-QIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQD 279 D RI ++A Y G P +++ + + + D + R + Q + D R+K+ Sbjct: 176 DDRIVFEANTVYNGHYPAKVEKMTWFLLSDDAARVTAQESGRVQAIESVPYLDAERLKRK 235 Query: 280 KSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIP 339 ++ ++ GL +L +N +K P D+ KVRQAL YA++K +I V+ G +A + + Sbjct: 236 NNVESVQSFGLL--FLMFNCEKAPFDNPKVRQALHYALDKQKLIDIVFLGNAKAATSYLQ 293 Query: 340 PTMWGYNDDVQDYTYDPEKAKALLKEAGL 368 T Y Y YD KA+ LL EAG+ Sbjct: 294 DTHPDYVKASSQYDYDKAKAEKLLAEAGI 322 >3TCF-A nrPDB Length = 524 Score = 117 bits (294), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 122/488 (25%), Positives = 207/488 (42%), Gaps = 60/488 (12%) Query: 76 PGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQ--KNAQNPYH 133 PG+AE W+ ++D K +TFHLRK KW D + A D V+S+ R N +PY Sbjct: 59 PGVAESWD-NKDAKVWTFHLRKDAKWSDGTP------VTAQDFVYSWQRSVDPNTASPY- 110 Query: 134 KVSGGSY-EYFEGMGLPELISE--------VKKVDDNTVQFVLTRPEAPFLADLAMDFAS 184 SY +Y G+ E++ VK +DD+T++ L+ P F L S Sbjct: 111 ----ASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTS 166 Query: 185 ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLV 243 + K A+ K G N + G + L+ + + RI + YW K I+ + Sbjct: 167 PVPKA---AIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVT 223 Query: 244 FSITPDASVRYAKLQKNECQVMPYPNPADI-ARMKQDKSINLMEMPGLNVGYLSYNVQKK 302 + + + E + P ++ ++K++ + P L Y N QK Sbjct: 224 YLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP 283 Query: 303 PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPP----------TMWGYNDDVQDY 352 P +DV+VR AL +++D I+ V + A PP +G++ + ++ Sbjct: 284 PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRN- 342 Query: 353 TYDPEKAKALLKEAGL--EKGFSIDLWAMPVQRPYNPN--ARRMAEMIQADWAK-VGVQA 407 E+AK LL EAG +K +I+L YN + +++A + W K +GV Sbjct: 343 ----EEAKKLLAEAGYTADKPLTINLL-------YNTSDLHKKLAIAASSLWKKNIGVNV 391 Query: 408 KIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPF 467 K+V EW +L G GW D +P +F T+ S ++ N + + F Sbjct: 392 KLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSS----MNTAHYKSPAF 447 Query: 468 EDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGK 526 + ++ D +R LY +A+ + + + + + V+ V GY DPL Sbjct: 448 DSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDN 507 Query: 527 HHFENVSI 534 + N+ I Sbjct: 508 TYTRNMYI 515 >4ZE8-A nrPDB Length = 499 Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 116/453 (25%), Positives = 196/453 (43%), Gaps = 42/453 (9%) Query: 73 EVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKN-AQNP 131 +++P LAE WE D K+ F LR+ V +HD E L ADDV ++F ++ Sbjct: 55 DLVPALAESWE-RIDEKSVRFKLRQKVMFHDGVE------LTADDVAYTFSSERLWGPEA 107 Query: 132 YHKVS-GGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEY 190 K+ G SY + E + E D TV P +A + I+ KEY Sbjct: 108 IKKIPLGKSY----SLDFDEPVVE----DKYTVTLRTKTPSYLIETFVASWMSRIVPKEY 159 Query: 191 ADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDA 250 + K P+GTGP++ ++ R+ +A D YWG KP + + I + Sbjct: 160 YKKLGAVDFGNK----PVGTGPYKFVEFVAGDRVVLEANDAYWGPKPTASKITYQIVAEP 215 Query: 251 SVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVR 310 + R A L E ++ P DI + + N ++N+ ++ D K+R Sbjct: 216 ATRVAGLISGEYDIITTLTPDDIQLINSYPDLETRGTLIENFHMFTFNMNQEVFKDKKLR 275 Query: 311 QALTYAVNKDAIIKAVYQG-AGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLE 369 +AL AVN+ +++A+++ A + A P ++ + Y+ E+AK L+KE+G + Sbjct: 276 RALALAVNRPIMVEALWKKQASIPAGFNFPNYGETFDPKRKAMEYNVEEAKRLVKESGYD 335 Query: 370 KGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTV 429 G I M Y NA M+ W ++GV + TY G + ++QT Sbjct: 336 -GTPITYHTM---GNYYANAMPALMMMIEMWKQIGVNVVMKTYAPGSF-----PPDNQTW 386 Query: 430 MMGWTGDNGDPDNFFATLFSCAASEQGSN---YSKWCYKP---FEDLIQPARATDDHNKR 483 M W+ NG + ++ E G N +W +K F +L Q + +R Sbjct: 387 MRNWS--NG---QWMTDAYATIVPEFGPNGQVQKRWGWKAPAEFNELCQKVTVLPNGKER 441 Query: 484 VELYKQAQVVMHDQAPALIIAHSTVFEPVRKEV 516 + Y + + + ++APA+I+ RK+V Sbjct: 442 FDAYNRMRDIFEEEAPAVILYQPYDVYAARKDV 474 >2Z23-A nrPDB Length = 517 Score = 113 bits (282), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 115/480 (23%), Positives = 211/480 (43%), Gaps = 40/480 (8%) Query: 74 VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQ--NP 131 ++PG AE W+ ++D K +TF++RK KW + + A D V+S+ R + + +P Sbjct: 56 IVPGAAESWD-NKDFKVWTFNIRKDAKWSNGDP------VTAQDFVYSWQRLADPKTVSP 108 Query: 132 YHKVSGGSY-----EYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADL-AMDFASI 185 Y ++ + G P+ + VK +DD+T++ L+ P P+L L A S Sbjct: 109 YASYLQYAHLTNIDDIITGKAAPDTLG-VKALDDHTLEVTLSEP-VPYLDKLLAHPLMSP 166 Query: 186 LSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFS 245 ++K + + T + N +G G ++L+ + + RI + YW + V Sbjct: 167 VNKTVVEKFGEKWTQPQ---NFVGNGAYKLKDWIVNERIVLERSPTYWDNAKTVINQVTY 223 Query: 246 ITPDASVRYAKLQKNECQVMPYPN-PADI-ARMKQDKSINLMEMPGLNVGYLSYNVQKKP 303 + + V ++ M Y N P ++ ++K++ + P L Y N QK P Sbjct: 224 LPISSEVTDVNRYRSGEIDMTYNNMPIELFQKLKKEIPDQVHVDPYLCTYYYEINNQKAP 283 Query: 304 LDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQD-YTYDPEK---- 358 D +VR+AL +++D I+ V + A PP G + +++ EK Sbjct: 284 FTDARVREALKLGMDRDIIVNKVKNQGDLPAYGFTPPYTSGAELTPPEWFSWTQEKRNEV 343 Query: 359 AKALLKEAGLEKGFSIDLWAMPVQRPYNPN--ARRMAEMIQADWAK-VGVQAKIVTYEWG 415 AK LL EAG K + + YN + +++A + W K +GV K+ EW Sbjct: 344 AKKLLAEAGYTKDNPLKFSLL-----YNTSDLHKKLAIAAASIWKKNLGVDVKLENQEWK 398 Query: 416 EYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPAR 475 +L G + W D +P +F + S ++ +N + + F+ LI+ Sbjct: 399 TFLDTRHQGTYDVARAAWCADYNEPSSFLNMMLSNSS----NNTTHYKSSVFDKLIEDTL 454 Query: 476 ATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 +R +LY+QA++ + + + + + V+ V GY DPL H +++ I Sbjct: 455 KVKSEKERADLYQQAEIQLDKDSAIVPVFYYVSARLVKPYVGGYTGKDPLDNMHVKDLYI 514 >4WED-A nrPDB Length = 525 Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 98/409 (23%), Positives = 178/409 (43%), Gaps = 48/409 (11%) Query: 60 LYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVV 119 ++ LV++ G ++ P LA W++ + GKT LR+GVK+ D +F +A Sbjct: 64 MFEPLVKYGKGG-QIEPCLATDWKIEDGGKTLHLTLREGVKFQDGTKF------DAAACK 116 Query: 120 FSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLA 179 ++ +R + F M + ++ VDD + P + +L+ Sbjct: 117 WNLERWMG------------IDQFSWMNCSKHFQSLEVVDDYHITVHFKEPVLALMQELS 164 Query: 180 MDFAS-ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQ 238 + LS + DA K P+GTGP+ +Q D++ ++ +DGYWG KP Sbjct: 165 YTRPTRFLSPKSVDADGKFK-------EPVGTGPW-VQISADDTQSVFEHYDGYWGDKPT 216 Query: 239 IDTLVFSITPDASVRYAKLQKNECQVMP----YPNPADIARMKQDKSINLMEMPGLNVGY 294 + L + PDA R A L+ E ++ P + + + N++ PG Sbjct: 217 YERLEAKVIPDARSRVAALRAGEIDLVGGFWIAPLTPEEGKQLEAAGFNVVVDPGNVTLV 276 Query: 295 LSYNVQK-KPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYT 353 +++N + +PL D +VR+A++ +++ AI K +Y G A N+ + Sbjct: 277 MAFNPDRAEPLKDPQVRKAVSIGIDRAAISKVLYHGYAKPAGNMFSAALPYAGKQFDAPV 336 Query: 354 YDPEKAKALLKEAGLE---------KGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVG 404 D A ALL++AG K +++L P P +R +AE+IQ++ +VG Sbjct: 337 RDAAAASALLEKAGWTGSPIRSKDGKPLTLELVVSP---DAVPGSRVIAEVIQSEMKEVG 393 Query: 405 VQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAAS 453 + I + ++ + D Q +G+ G P + F +L + S Sbjct: 394 IDLVIRSV---DHASKHTDMLEQKYDLGFFLTYGAPYDPFGSLVALCLS 439 >3O9P-A nrPDB Length = 519 Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 102/466 (21%), Positives = 191/466 (40%), Gaps = 37/466 (7%) Query: 73 EVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQ--N 130 E++PG+A +W+ S D + +TF LR KW D + A D V+S+ R + + + Sbjct: 59 EIVPGVATQWK-SNDNRIWTFTLRDNAKWADGTP------VTAQDFVYSWQRLVDPKTLS 111 Query: 131 PYHKVSG-----GSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASI 185 P+ + + +G P+ + V VD +T++ L +P P+ +L +FA Sbjct: 112 PFAWFAALAGINNAQAIIDGKATPDQLG-VTAVDAHTLKIQLDKP-LPWFVNLTANFAFF 169 Query: 186 LSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYW-GTKPQIDTLVF 244 ++ A +++G N IG G + L++ + ++ YW K + + F Sbjct: 170 PVQK---ANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQKVTF 226 Query: 245 SITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPL 304 S + + + ++ +D + P L Y ++N QK P Sbjct: 227 LPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPT 286 Query: 305 DDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPE-----KA 359 D +VR AL+ +++ + + V A + P G+ + + + +A Sbjct: 287 ADQRVRLALSMTIDRRLMTEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQA 346 Query: 360 KALLKEAGLEKGFSIDLWAMPVQRPYNP--NARRMAEMIQADWAK-VGVQAKIVTYEWGE 416 K LL AG + L + YN N +++A + + W K +GV K+ EW Sbjct: 347 KTLLSAAGYGPQKPLKLTLL-----YNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKT 401 Query: 417 YLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARA 476 Y+ G + W GD +P F L S N S++ ++ ++ A Sbjct: 402 YIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTST----HSGNISRFNNPAYDKVLAQAST 457 Query: 477 TDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVD 522 + R Y A+ ++ +QAP I T ++ +KGY ++ Sbjct: 458 ENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPIN 503 >4PFU-A nrPDB Length = 547 Score = 92.4 bits (228), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 126/493 (25%), Positives = 207/493 (41%), Gaps = 60/493 (12%) Query: 39 PEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKG 98 P +NP FT ++ +Y + + T P LAEK E D KTY LR+G Sbjct: 19 PSNWNP--FTPWNAVPGTTGLVYETMFFYDPLTGNFDPWLAEKGEWL-DSKTYRVVLREG 75 Query: 99 VKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKV 158 + WHDN L ++DV F+F+ K K G Y + E + ++ Sbjct: 76 IYWHDN------VPLTSEDVRFTFEIAK-------KYKGIHYS-----SVWEWLDHIETP 117 Query: 159 DDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY 218 D+ TV FV P +L I+ K + + + + P+G+GP+ + Sbjct: 118 DNRTVIFVFKDPRYHEWNELLYTLP-IVPKHIWEEKDETTILQSSNEYPLGSGPYVAHSW 176 Query: 219 QKDSRIRYKAFDGYWGTK-----PQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADI 273 ++ I ++ F+ +WGTK P +V +V L K E + P + Sbjct: 177 DQNKMI-FERFENWWGTKVMGVKPAPKYVVIVRVLSNNVALGMLMKGELDFSNFMLPG-V 234 Query: 274 ARMKQDKSINLM------EMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVY 327 +K+ ++N + VG L N +K PL + R+A+ ++N D I++ VY Sbjct: 235 PILKKVYNLNTWYDEPPYHLSSTVVG-LFLNARKYPLSLPEFRRAIAMSINADPIVQRVY 293 Query: 328 QGAGVSAKNL--IPPTMWG--YNDDV---QDYTYDPEKAKALLKEAGLE----KGFSIDL 376 +GA + A L +P ++W Y +V + YDPE+AK++L + G GF Sbjct: 294 EGAVLKADPLGFLPNSVWMKYYPKEVVEKHGFKYDPEEAKSILDKLGFRDVNGDGFRETP 353 Query: 377 WAMP----VQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVM- 430 P ++ PY A + D K VG+ A+ + +Y + GE M Sbjct: 354 DGKPIKLTIECPYGWTDWMQAIQVIVDQLKVVGINAEPYFPDSSKYYENMYKGEFDIEMN 413 Query: 431 MGWTGDNGDPDNFFATLFSCAASEQ----GSNYSKWCYKPFEDLIQPARAT--DDHNKRV 484 TG + P +F T+F A E NY ++ E L++ T D+ K Sbjct: 414 ANGTGISSTPWTYFNTIFYPDALESEFSYTGNYGRYQNPEVESLLEELNRTPLDNVEKVT 473 Query: 485 ELY-KQAQVVMHD 496 EL K ++++ D Sbjct: 474 ELCGKLGEILLKD 486 >3T66-A nrPDB Length = 496 Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 112/510 (21%), Positives = 205/510 (40%), Gaps = 66/510 (12%) Query: 34 CSEGSPEGFNPQLFTSGTT-----YDASSVPLYNRLVEFKIGTTE----VIPGLAEKWEV 84 +EG+ E LF T D + +P+ + E + E + P LAE W+ Sbjct: 6 SNEGAGEKHIHFLFNVSTNSLDPHVDMTYIPVRAGITETLVRVDEENVTIAPWLAESWD- 64 Query: 85 SEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFE 144 S DG+ +T LR+ V + + KE ++A+ V S +R + S Sbjct: 65 STDGQHWTIKLREDVTFQNGKE------MDAEAVKASLERALDE----------SVAIEN 108 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 + + E+ + D T+ P F+++L SI+ T E Sbjct: 109 ALKIDEI-----EADGYTLHITTKEPFPEFISELVNPNVSIIDV----------TEEDFT 153 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQV 264 +P+GTGPF L+ + S++ +D YW ++D++ FS DAS R L+ + + Sbjct: 154 NHPVGTGPFALESFTPGSKLELVRYDEYWDGASKLDSVTFSFNEDASARSLALESGQADI 213 Query: 265 MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIK 324 + P I ++ ++ I + L+ N+ + L DV VR+A+ +++ I+ Sbjct: 214 VYRPEVESIETLQANEGIMVEATETFRTHNLTMNLDRDSLKDVNVRRAVDVLLDRQEIVD 273 Query: 325 AVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAG--LEKG----------F 372 + G A PT+ + + + A L+EAG LE G F Sbjct: 274 TIMLGYAEVADGPFIPTL-PFAPSYEKKETGTDIAIQYLEEAGYTLENGQMQKDGEPLHF 332 Query: 373 SIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEW-GEYLKRAKDGEHQTVMM 431 ++ + + P +A++ Q++ ++G++ +I E EY+ +D + T Sbjct: 333 TVLTYGSRAELPL------IAQVFQSNAKQIGIEVEIRQIEVPEEYMASNRDWDLIT-YS 385 Query: 432 GWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQ 491 T GD + + + N+S +I T D + R +L +QA Sbjct: 386 NVTSPRGDAGYYLNATYHPTGA---LNFSSVNDPELTGIIDELNRTVDQDVRAKLTEQAA 442 Query: 492 VVMHDQAPALIIAH-STVFEPVRKEVKGYV 520 + +Q + H S V +VK +V Sbjct: 443 AYIDEQKIHSFLIHPSAVVAYDENKVKNWV 472 >6DQU-A nrPDB Length = 530 Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 124/530 (23%), Positives = 213/530 (40%), Gaps = 52/530 (9%) Query: 31 LVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKT 90 +V + P+ F+P T G + L LV ++ PG AE WE + D KT Sbjct: 16 IVINNGAEPQSFDPHK-TEGVPESNVAYQLLEGLVTSD-SEGKLQPGAAESWENTPDFKT 73 Query: 91 YTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSY-------EYF 143 +TFHLRK KW + + A D VF++ R + S SY + Sbjct: 74 WTFHLRKDAKWSNGD------PVTAHDFVFAWRRLVDPATAAPYASYLSYLQVENAQDII 127 Query: 144 EGMGLP-ELISEVKKVDDNTVQFVLTRPEAPFLADLA-----MDFASILSKEYADAMMKA 197 +G P EL E K DD T T P P+ L + + ++ DA +K Sbjct: 128 DGKKKPAELGVEAK--DDYTFVVHATNP-VPYAVSLTTHQSLLPLPQKVVEKLGDAWVKK 184 Query: 198 GTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQ-IDTLVFSITPDASVRYAK 256 N +G G ++L + + +I ++ YW K I++ F + S A+ Sbjct: 185 E-------NYVGNGAYKLANHIINEKIEFERNPLYWNDKETVINSATFLAIENPSTDVAR 237 Query: 257 LQKNECQVMPYPNPAD-IARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTY 315 + + + Y P + A++K++ + L N +K P D+V +R+AL Sbjct: 238 YRAGDLDMTSYGLPPEQFAKLKKELLGEVYVTRTLGTYSYELNNKKAPFDNVNIRKALNL 297 Query: 316 AVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQD--YTYDP-----EKAKALLKEAGL 368 +++++ I V G G + + PT +Q Y+ +P E+A LL+EAG Sbjct: 298 SLDRNVITDKVL-GQGQTPTYVFTPTYIEEGHLIQQPAYSKEPMAQRNEEAIKLLEEAGY 356 Query: 369 EKGFSIDLWAMPVQRPYNPNARRMAEMIQADW---AKVGVQAKIVTYEWGEYLKRAKDGE 425 K + + N N +++A + W K + K+ EW Y+ + G Sbjct: 357 SKANPLKF---SILYNTNENHKKVAIAAASMWKANTKGLIDVKLENQEWKTYIDSRRAGR 413 Query: 426 HQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVE 485 + GW D F S ++ +N +K+ ++ + + A D R + Sbjct: 414 YDVARAGWHADYNQATTFGNYFLSNSS----NNTAKYANPEYDKAMAESYAATDAEGRAK 469 Query: 486 LYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 Y +A+ ++ + I + V+ VKGY DP + N+ I Sbjct: 470 AYAKAEEILGKDYGIVPIFNYVNPRLVKPYVKGYSGKDPQDHIYLRNLYI 519 >4PFT-A nrPDB Length = 544 Score = 91.7 bits (226), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 120/491 (24%), Positives = 210/491 (42%), Gaps = 58/491 (11%) Query: 39 PEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKG 98 P +NP FT + +Y L + + P LAEK E + + Y LRKG Sbjct: 19 PSNWNP--FTPWNAVAGTIGLVYEPLFLYDPLNDKFEPWLAEKGEWVSNNE-YVLTLRKG 75 Query: 99 VKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKV 158 ++W D L ADDVVF+F+ K K +G SY + + +++V Sbjct: 76 LRWQDG------VPLTADDVVFTFEIAK-------KYTGISYS-----PVWNWLGRIERV 117 Query: 159 DDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY 218 D+ T++FV + P + ++ I+ K + + + + NP+G+GP+ ++ + Sbjct: 118 DERTLKFVFSDPRYQEWKQMLIN-TPIVPKHIWENKTEEEVLQAANENPVGSGPYYVESW 176 Query: 219 QKDSRIRYKAFDGYWGTK-----PQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADI 273 D R +K +WG + P+ + +V +V L K E + P + Sbjct: 177 A-DDRCVFKKNGNWWGIRELGYDPKPERIVELRVLSNNVAVGMLMKGELDWSNFFLPG-V 234 Query: 274 ARMKQDKSI-----NLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 +K+ I N M N + NV K PL + R+A+ YA+N + I+ Y+ Sbjct: 235 PVLKKAYGIVTWYENAPYMLPANTAGIYINVNKYPLSIPEFRRAMAYAINPEKIVTRAYE 294 Query: 329 GAGVSAKN-----LIPPTMWGYNDDVQD---YTYDPEKAKALLKEAGL----EKGFSIDL 376 V+A N +P M Y +V D + YDPE AK +L E G + GF D Sbjct: 295 NM-VTAANPAGILPLPGYMKYYPKEVVDKYGFKYDPEMAKKILDELGFKDVNKDGFREDP 353 Query: 377 WAMP----VQRPYNPNARRMA-EMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMM 431 P ++ PY ++ + I D KVG+ + ++ +Y G+ ++ Sbjct: 354 NGKPFKLTIECPYGWTDWMVSIQSIAEDLVKVGINVEPKYPDYSKYADDLYGGKFDLILN 413 Query: 432 GW-TGDNGDPDNFFATLFSCAASEQ----GSNYSKWCYKPFEDLI-QPARATDDHNKRVE 485 + TG + ++F +F A E N+ K+ E L+ + R+ DD + Sbjct: 414 NFTTGVSATIWSYFNGVFYPDAVESEYSYSGNFGKYANPEVETLLDELNRSNDDAKIKEV 473 Query: 486 LYKQAQVVMHD 496 + K +++++ D Sbjct: 474 VAKLSEILLKD 484 >3ZS6-A nrPDB Length = 506 Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 111/473 (23%), Positives = 188/473 (39%), Gaps = 55/473 (11%) Query: 74 VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYH 133 V+PG+A+ WE + T+ F LR+ KW + + + A D V+++ R + + Sbjct: 48 VVPGVAQAWE-HKAPDTWIFKLRRDAKWSNGQP------VTAADFVYAWQRLADPK---- 96 Query: 134 KVSGGSY----EYFEGMGL------PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFA 183 +G Y E+ + P ++ +D T++ P + F AM Sbjct: 97 --TGSKYTILVEFVKNASAIIAGKQPPGDLGIRAIDPYTIEVKTEVPVSYFPELTAMAPL 154 Query: 184 SILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK----PQI 239 + ++K DA+ K G N + GP+ L +Q ++RI D YW + ++ Sbjct: 155 TPVNK---DAVAKFGDAWTRPKNIVSNGPYTLVDWQPNNRIVMAKSDKYWNARNVVIRKV 211 Query: 240 DTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNV 299 L A Y Q + +P I+ K PGL + Y + Sbjct: 212 TYLPIENDETALRMYQAGQIDYTYSIPAGGFGQIS-----KQFGKELRPGLQLATYYYYL 266 Query: 300 QKK--PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQ-DYTYDP 356 + L D +VR+AL ++++ + + Q V L+P + G D+ P Sbjct: 267 KNSDPALKDKRVREALAMVLDREILTSKITQAGEVPMYGLMPKGVKGVQRPFTPDWASWP 326 Query: 357 -----EKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN--ARRMAEMIQADW-AKVGVQAK 408 + AK LLK+AG D + YN N +++A ++W K+GV AK Sbjct: 327 MARRVDYAKNLLKQAG-----HGDANPLTFTLTYNTNDLHKKVALFAASEWRTKLGVTAK 381 Query: 409 IVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFE 468 + E+ +K+ DG+ Q GW D D FF L C +S+ Y C + Sbjct: 382 LENVEFKVLMKQRHDGKVQIARDGWFADYNDAMTFF-DLIRCGSSQNTVGY---CNPKVD 437 Query: 469 DLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVV 521 L+ A D R L QA + + P + + + V+ V GY + Sbjct: 438 SLVAEANQKLDDGARAALLTQAHDLAMNDYPMVPLFQYSADRLVKSYVGGYTL 490 >4XKN-A nrPDB Length = 473 Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 79/350 (22%), Positives = 145/350 (41%), Gaps = 24/350 (6%) Query: 186 LSKEYADAMMKA-GTPEKLDLN--PIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTL 242 L E A+ M T K D+N P+GTGP+Q++ Y++ +I F YW KP++D + Sbjct: 126 LVSELANPFMAIYDTDAKSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDHI 185 Query: 243 VFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKK 302 + D + R L+ + ++ + ++ ++++ + + G L YN K Sbjct: 186 TVTYQEDGNNRVRNLESQKDDLITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNK 245 Query: 303 PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDP------ 356 + VR+AL + +++ I +YQG P +ND + Y +P Sbjct: 246 KMTK-SVREALDHIIDRQGIADHIYQGYA-------KPATSPFNDKIP-YIKEPKLTKQN 296 Query: 357 -EKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWG 415 E+AK LL + G K + + + P ++A+++Q+D K ++ I + + Sbjct: 297 IEQAKMLLAKDGYTKEHPLKIKLITYDG--RPELSKIAQVLQSDAKKANIEIDIKSVDDI 354 Query: 416 EYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPAR 475 E + + T+ T GD FF + + +Y+ +DLI Sbjct: 355 EGYLKDRSAWDATMYSFGTIPRGDTGYFFNQAYKKDGAINKGDYNNSN---VDDLINQLN 411 Query: 476 ATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLG 525 T D +R + + P IA++ +VK Y V P G Sbjct: 412 HTVDVKERHNISNDIIKLSSRDVPNSYIAYNDQIVAANSKVKNYKVTPEG 461 >4OFL-A nrPDB Length = 499 Score = 72.0 bits (175), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 83/340 (24%), Positives = 142/340 (41%), Gaps = 47/340 (13%) Query: 40 EGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGV 99 EGF+P L S +Y PL + +F + L +++ S+DGKT+ L+ + Sbjct: 15 EGFDPMLGWSHGSYLLLHSPLLKQNEDFSWDSL-----LLSQYQPSDDGKTWLLTLKPDL 69 Query: 100 KWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVD 159 K+ D L A DV F+++ NA KV G++ L +EV +D Sbjct: 70 KFSDGSP------LTAKDVAFTYN---NAAASGGKVDMGNF----------LSAEV--ID 108 Query: 160 DNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQ 219 V+ L P++ F+ L I+S + +A A PIG GP++L +Q Sbjct: 109 PLNVRIHLKAPQSTFVNVLGS--LGIVSADKYNAKTYA-------QKPIGAGPYRLVSFQ 159 Query: 220 KDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMK-- 277 ++ +A Y G K D L+F + D +A Q + V+ P + + Sbjct: 160 PGQQMIVEANPYYAGNKNDFDKLIF-VFLDEDSAFAAAQSGQLGVVRIPPSMAVGSVNNM 218 Query: 278 --------QDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQG 329 +++ I P Y + DV +R+A+ YA+N+ + + +G Sbjct: 219 KLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTADVAIRRAINYAINRQLLADQIMEG 278 Query: 330 AGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLE 369 + A + W N D D +KAK +L++AG + Sbjct: 279 HAIPAYTGVQGLPWN-NPDSAIKDGDIDKAKQILEQAGWQ 317 >5KZT-A nrPDB Length = 536 Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 108/489 (22%), Positives = 195/489 (39%), Gaps = 68/489 (13%) Query: 74 VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYH 133 I G AE+ ++S+D YT LR+ KW + + A+D V+S+ R A +P Sbjct: 59 AIAGAAEEPKISDDKTVYTIKLREDAKWSNGD------PVTANDYVYSWRR---AVDPN- 108 Query: 134 KVSGGSYEYF-----------EGMGLPELISEVKKVDDNTVQFVLTRPEA--------PF 174 + +Y Y G PE + +K VDD T++ L++P A P Sbjct: 109 --TAATYSYLFDAIKNGGDIVAGKKKPEELG-IKAVDDYTLEVTLSKPTAYINSLFAFPT 165 Query: 175 LADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQ-KDSRIRYKAFDGYW 233 L F + ++YA N + GPF+L+ + + + Y D YW Sbjct: 166 FFPLNEKFVTEKGEKYAQNSD----------NMLFNGPFELKDWTGTNKKWTYVKNDKYW 215 Query: 234 GT-KPQIDTLVFSITPDA--SVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGL 290 K ++ + + D+ + K + V+ AD A ++ + + + Sbjct: 216 DKDKVKLKQINVQVVQDSGTGLNLYNTDKVDRTVL----SADYAAQNKNNK-DYVTVNNS 270 Query: 291 NVGYLSYNVQKKPLDDV----KVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYN 346 + Y+ +N ++ D V +R+A+ A++K + V + A NL+P Sbjct: 271 STFYIKFNQKRAGKDTVFANKNIRKAIALAIDKQSYTDTVLKNGSKPANNLVPEGFTFDP 330 Query: 347 DDVQDYT--------YDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQA 398 + +DYT YD ++A+ K AGL K ++ + NAR+ +E IQ Sbjct: 331 GNKEDYTKESGKHLEYDVKEAQKAWK-AGL-KELGVNEITVEFTSDDTENARKSSEFIQD 388 Query: 399 DWAKV--GVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQG 456 K G+ K+ + L+ ++ ++ M GW D DP F LF ++ Sbjct: 389 QLQKNLDGLTVKLKNVPFKVRLQNDQNQDYDFSMSGWGPDYQDPSTFL-DLFVTDGAQNR 447 Query: 457 SNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEV 516 +YS Y + A DD + E+ K ++++ D + + + + Sbjct: 448 MSYSNKDYDKILNDASVTYAADDQKRWDEMVKAEKILLTDDVAIQPLYQRSTAYLQKDYI 507 Query: 517 KGYVVDPLG 525 K +P G Sbjct: 508 KNLQKNPFG 516 >1ZTY-A nrPDB Length = 529 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 119/492 (24%), Positives = 202/492 (41%), Gaps = 75/492 (15%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFK--IGTTEVIPGLAEKWEVSEDGKTYTFHLRKGV 99 FNP L T+ T ++ +Y LV F G T V LAE +++++D + TF +RKGV Sbjct: 18 FNPYLATNLRT---TTDFIYEPLVVFNEMKGNTPVF-RLAESYKMADDLMSVTFDIRKGV 73 Query: 100 KWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVD 159 KW D + F ADDVV+SF K + G+ + ++ V+KVD Sbjct: 74 KWSDGEAF------TADDVVYSFGLLKAKPE------------LDQRGINKWVTSVEKVD 115 Query: 160 DNTVQFVLTRPEA--PFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQ-LQ 216 + V+F L+ + P+ L A + K+ D NP+GTGPF + Sbjct: 116 EYKVRFRLSEANSNVPYEISLIPIVAEHVWKDVKDPTTFTNE------NPVGTGPFTVID 169 Query: 217 QYQKDSRIRYKAFDGYW-GTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIAR 275 + I+ + YW ++D L + K+ +E P DI R Sbjct: 170 TFTPQLYIQCRN-PNYWDAANLEVDCLRVPQIANNDQLLGKIVNSELDWTSSFVP-DIDR 227 Query: 276 MKQDKSIN---LMEMPGLNVGYLSYN----VQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 + N G +++ +K+ LD+V R+A + A+++ II + Sbjct: 228 TYAAANPNHHYWYPAAGTQAFMVNFKNPDPAKKEALDNVDFRRAFSMALDRQTIIDIAFY 287 Query: 329 GAGVS---AKNL-IPPTMWGYNDDVQDY----TYDPEKAKALLKEAGLE----KGF---- 372 G+G A L W + Y TYD E +K LL +AG + GF Sbjct: 288 GSGTVNDFASGLGYAFEAWSDEATHKKYKGFNTYDVEGSKKLLAKAGFKDVNGDGFVETP 347 Query: 373 SIDLWAMPVQRP-----YNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQ 427 S + + +Q P +N + E +Q +VG++AK T E+ Y + +G + Sbjct: 348 SGKSFELLIQSPNGWTDFNNTVQLAVEQLQ----EVGIKAKARTPEFAVYNQAMLEGTYD 403 Query: 428 TVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFED-----LIQPARATDDHNK 482 + DP ++ + ++ A + G ++ F D L+ T D N+ Sbjct: 404 VAYTNYF-HGADPFTYWNSGYNSAL-QSGDGMPRFAMHYFTDKKLDGLLDSFYKTADKNE 461 Query: 483 RVELYKQAQVVM 494 ++ + Q ++ Sbjct: 462 QLAIAHGIQKII 473 >2D5W-A nrPDB Length = 603 Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 105/248 (42%), Gaps = 36/248 (14%) Query: 304 LDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALL 363 L+D + RQA+ +A+N++ ++KA + G A I P +N +V+ Y +D +KA+ALL Sbjct: 322 LNDKRTRQAILHALNREGLVKAFFDGLQPVAHTWIAPVNPLFNPNVKKYEFDLKKAEALL 381 Query: 364 KEAGLEKG---------------FSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAK 408 E G KG F I+ V N R + D K+G+ K Sbjct: 382 AEMGWRKGPDGILQRTVNGRTVRFEIEY----VTTAGNVVRERTQQFFAEDLKKIGIAVK 437 Query: 409 I------VTYEWGEYLKRAKDGEHQTVM-MGWTGDNGDPDNFF--------ATLFSCAAS 453 I V + E+++RA + + + W + + + F A + + Sbjct: 438 INNAPSAVVFA-DEFIQRASECKWTGMFEFAWVSNLQEDGSLFQYKNLNTGAIMVPTKEN 496 Query: 454 E-QGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPV 512 QG N W F+ L A D +R +L+ +AQ + ++ PAL + V Sbjct: 497 NYQGQNIGGWRNDEFDRLTSQAVLEFDPERRKQLFWRAQEIWAEELPALPLYFRANPYVV 556 Query: 513 RKEVKGYV 520 RK + YV Sbjct: 557 RKGLVNYV 564 >3DRH-A nrPDB Length = 590 Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 90/384 (23%), Positives = 149/384 (38%), Gaps = 68/384 (17%) Query: 73 EVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKN----- 127 + I G A + ++ KT T LRK +KW D E+ A D F+++ N Sbjct: 80 KFIKGGAADVALDKESKTATITLRKDLKWSDG------SEVTAKDYEFTYETIANPAYGS 133 Query: 128 -----------AQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRP------ 170 + YH G + G+ P+ E KV VQF +P Sbjct: 134 DRWTDSLANIVGLSDYHT---GKAKTISGITFPD--GENGKVI--KVQFKEMKPGMTQSG 186 Query: 171 EAPFLADLA--MDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKA 228 FL +A + K+ A + K P+ TGPF+ + I+Y Sbjct: 187 NGYFLETVAPYQYLKDVAPKDLASS-------PKTTTKPLVTGPFKPENVVAGESIKYVP 239 Query: 229 FDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMP 288 YWG KP+++++ + + A A L ++ ++ + ++K K ++ Sbjct: 240 NPYYWGEKPKLNSITYEVVSTAK-SVAALSSSKYDIINGMVSSQYKQVKNLKGYKVLGQQ 298 Query: 289 GLNVGYLSYNV-------------QKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAK 335 + + + YN+ +K PL D VRQA+ YA N + G A Sbjct: 299 AMYISLMYYNLGHYDAKNSINVQDRKTPLQDQNVRQAIGYARNVAEVDNKFSNGLSTPAN 358 Query: 336 NLIPPTMWGY-NDDVQDY-TYDPEKAKALLKEAGLEKGFSI--------DLWAMPVQRPY 385 +LIPP + + V+ Y D +KA LL E G + S +L + R Sbjct: 359 SLIPPIFKQFTSSSVKGYEKQDLDKANKLLDEDGWKLNKSTGYREKDGKELSLVYAARVG 418 Query: 386 NPNARRMAEMIQADWAKVGVQAKI 409 + NA +A+ W K+GV+ + Sbjct: 419 DANAETIAQNYIQQWKKIGVKVSL 442 >6EQ0-A nrPDB Length = 683 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 52/156 (33%), Positives = 73/156 (46%), Gaps = 23/156 (14%) Query: 20 MTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTT--YDASSVPLYNRLVE----FKIGT-- 71 M V T+ + G PEG+N + +G + + + L L F++ Sbjct: 78 MPDGVGVYGDTMRHVVGGRPEGWN---YIAGQSQGWGGIDIALSECLTRTAPLFQVDAKD 134 Query: 72 TEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNP 131 TE +P LA+ WE SEDG T T HL KG KW D + F NADDV+F ++ N Sbjct: 135 TEPLPNLAKSWEWSEDGHTLTMHLVKGAKWSDGEAF------NADDVMFYWEDAVVDPNV 188 Query: 132 YHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVL 167 G S E F G G + +KK+DD TV++ Sbjct: 189 SPLGGGASPEAF-GEG-----TTLKKIDDYTVEWTF 218 >5YQW-A nrPDB Length = 532 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 113/524 (21%), Positives = 208/524 (39%), Gaps = 105/524 (20%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFK--IGTTEVIPGLAEKWEVSEDGKTYTFHLRKGV 99 FNP F T ++ +Y LV F G T V LAE +++S+D + TF +RKGV Sbjct: 20 FNP--FLGATNLHTTTDFIYEPLVVFNEMHGNTPVF-RLAENFQMSDDLMSVTFDIRKGV 76 Query: 100 KWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVD 159 KW D + F ADDVV+SF+ K + G+ ++ V+KV+ Sbjct: 77 KWSDGEAFT------ADDVVYSFNLVKEKPE------------LDQSGINSWVTGVEKVN 118 Query: 160 DNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKL-DLNPIGTGPFQ-LQQ 217 D V+F L+ + ++A ++ K K P + NP+G+GPF + Sbjct: 119 DYQVKFRLSEANSNVPYEIAK--VPVVPKH---VWSKVKDPSTFTNENPVGSGPFTVIDT 173 Query: 218 YQKDSRIRYKAFDGYWGTK---------PQIDT--------------LVFSITPDASVRY 254 + I+ + YW PQI S PD Y Sbjct: 174 FTPQLYIQCEN-PNYWDAANLDVDCLRVPQIANNDQFLGKVVNGEMDWTSSFVPDIDRTY 232 Query: 255 AKLQ-KNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQAL 313 A K+ P A + K + + + L +V R+A Sbjct: 233 AAASPKHHYWYPPAGTQAFVVNFKNPDA-----------------AKNEALTNVDFRRAF 275 Query: 314 TYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGY--------NDDVQDY-TYDPEKAKALLK 364 + A+++ II + G G + + + + +D + Y +Y+ E AK LL Sbjct: 276 SMALDRQTIIDIAFYGGG-TVNDFASGLGYAFEAWSDEKTHDKFKAYNSYNAEGAKKLLA 334 Query: 365 EAGL----EKGF----SIDLWAMPVQRP-----YNPNARRMAEMIQADWAKVGVQAKIVT 411 +AG + GF S + + +Q P +N + E + A+VG++A+ T Sbjct: 335 KAGFKDVNKDGFVDTPSGKSFELLIQSPNGWTDFNNTVQLAVEQL----AEVGIKARART 390 Query: 412 YEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCA--ASEQGSNYSKWCYK--PF 467 ++ Y + +G + + DP ++ + ++ A + + ++ YK Sbjct: 391 PDFSVYNQAMLEGTYDVAYTNYF-HGADPYTYWNSAYNSALQSGDGMPRFAMHFYKNEKL 449 Query: 468 EDLIQPARATDDHNKRVEL-YKQAQVVMHDQAPALIIAHSTVFE 510 + L+ T D +++E+ + Q++ DQ +++ + +++ Sbjct: 450 DGLLNSFYKTADKQEQLEIAHGIQQIIAQDQVTIPVLSGAYMYQ 493 >6NPO-A nrPDB Length = 546 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 103/472 (21%), Positives = 185/472 (39%), Gaps = 50/472 (10%) Query: 75 IPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDR----QKNAQN 130 IP AE SEDGK YTF LRK KW + + A D VF++ R + A+ Sbjct: 78 IPAAAESSTKSEDGKKYTFKLRKDAKWSNGD------SVTAKDFVFAWQRLLDPKTAAEY 131 Query: 131 PYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEY 190 + + E P VK VDD T++ L + FL +A L++++ Sbjct: 132 AFIAFPIKNAEAVNKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKF 191 Query: 191 ADAMMKAGTPEKLDLN-PIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP-QIDTLVFSITP 248 + + G L+ + + GPF L ++ + + K D YW K ++D + +S+ Sbjct: 192 ---VKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWKLKKNDQYWDKKTVKLDEINYSVVK 248 Query: 249 DASVRYAKLQKNECQ--------VMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQ 300 + + + V Y N + + + S + + G Q Sbjct: 249 EPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGG------Q 302 Query: 301 KKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYND--DVQDYTYD--- 355 PL K+R+A+ +++K + + A L+P + D D Q+ + Sbjct: 303 DTPLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVK 362 Query: 356 PEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAK--VGVQAKIVTYE 413 P+ KA +K D + NA+++ E ++ K GV I Sbjct: 363 PDAKKAAAAWEEAKKELGKDQVTIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQP 422 Query: 414 WGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQP 473 + + LK D ++ GW+ D DP T S+ N + + ++++I+ Sbjct: 423 FKQKLKLESDQDYDISYGGWSPDYADP----MTYLDMFESKHSHNQMSFSDQKYDEIIKK 478 Query: 474 A--RATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDP 523 A D KR E +A+ ++ ++ AL+ P+ + + YV+ P Sbjct: 479 AGGELMTDAKKRWEELGKAEELLLEEDVALV--------PLYQSARSYVMKP 522 >2WOP-A nrPDB Length = 562 Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 108/480 (22%), Positives = 193/480 (40%), Gaps = 74/480 (15%) Query: 76 PGLAE-KWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHK 134 P LAE EVS+ G+T+T+ LR+G+++ D + +DDV + R AQ+ Sbjct: 83 PDLAEGPGEVSDGGRTWTYRLRRGLRYDDGT------PITSDDVRHAVQR-VFAQD---V 132 Query: 135 VSGGSYEYFEGMGLPEL-----------ISEVKKVDDNTVQFVLTRPEAPFLADLAMDFA 183 + GG + PE + V D++T+ F LTRP + F +A A Sbjct: 133 LPGGPTYLIPLLDDPERPYPGPYRTDEPLRSVLTPDEHTIVFRLTRPFSDFDHLMAQPCA 192 Query: 184 SILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWG-----TKPQ 238 + + + ++ T +P +GP+++ +++ D+ + + + +W +P Sbjct: 193 APVPR-------RSDTGADYGRDPRSSGPYRVARHEPDTLLHLER-NPHWDRATDPIRPA 244 Query: 239 I-DTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLN-----V 292 + D + +I D V A+L E + A ++ + ++ N + Sbjct: 245 LPDRVELTIGLDVDVLDARLIAGEFDINLEGRGLQHAAQRRATADEVLRSHTDNPRTSFL 304 Query: 293 GYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKN----LIPPTMWGYND- 347 +++ P D+V VR+A+ YA +K I+ +G V+ + L PPT+ + D Sbjct: 305 HFVAMQPHIPPFDNVHVRRAVQYAADK--ILLQDARGGPVNGGDLTTALFPPTLPAHQDL 362 Query: 348 DV----QDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKV 403 D+ D D + A+A L AGL GF + QR R +A+ + A+V Sbjct: 363 DLYPTGPDLRGDLDAARAELAAAGLPDGFRA---VIGTQR---GKFRLVADAVVESLARV 416 Query: 404 GVQAKIVTYEWGEYLKRAKDGEHQTV--------MMGWTGDNGDPDNFFATLFSCAASEQ 455 G++ + + Y G +TV + W D F A L + Sbjct: 417 GIELTVKELDVATYFSLGA-GHPETVREHGLGLLVTDWGADFPTEYGFLAPLVD--GRQI 473 Query: 456 GSNYSKWCYKPFED-----LIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFE 510 N W +D LI T D R EL++ + + + A L + H Sbjct: 474 KRNGGNWNLPELDDPEVNALIDETLHTTDPAARAELWRAVERRVMEHAVLLPLVHDKTLH 533 >4FAJ-A nrPDB Length = 564 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 102/494 (20%), Positives = 198/494 (40%), Gaps = 84/494 (17%) Query: 83 EVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEY 142 +VS +GKTYT +R G KW D ++ A D V ++ R +P K + E Sbjct: 113 KVSNNGKTYTIVIRDGAKWSDG------TQITASDFVAAWQR---VVDP--KTVSPNVEL 161 Query: 143 FEGMGLPELISE---------VKKVDDNTVQFVLTRPEAPFLADLAMDFA-----SILSK 188 F + + I+ VK + + T++ L P P+ DL A K Sbjct: 162 FSAIKNAKEIASGKQAKDTLAVKSIGEKTLEIELVEP-TPYFTDLLSLTAYYPVQQKAIK 220 Query: 189 EYAD-------AMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP-QID 240 EY A++ G +L +GT K+ YW K +D Sbjct: 221 EYGKDYGVSQKAIVTNGAFNLTNLEGVGTSDKWTISKNKE----------YWDQKDVSMD 270 Query: 241 TLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM-KQDKSINLMEMPGLNVGYLSYNV 299 + F + + + N+ Q+ P + A+ K+DK + M N +L N Sbjct: 271 KINFQVVKEINTGINLY--NDGQLDEAPLAGEYAKQYKKDKEYSTTLMA--NTMFLEMNQ 326 Query: 300 --QKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDP- 356 + K L + VR+A+ YA+++++++K + V++ ++P M + +D+ + Sbjct: 327 TGENKLLQNKNVRKAINYAIDRESLVKKLLDNGSVASVGVVPKEMAFNPVNKKDFANEKL 386 Query: 357 ------------EKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKV- 403 +KAK KE L K S+DL + ++ E +Q Sbjct: 387 VEFNKKQAEEYWDKAK---KEIDLSKNTSLDLLVSDGEFE-----KKAGEFLQGQLQDSL 438 Query: 404 -GVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKW 462 G++ + +++R + + GW D DP +F A + + G + Sbjct: 439 EGLKVTVTPIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMNHGG----Y 494 Query: 463 CYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVD 522 K +++L++ D +KR + K+A+ ++ + + I + + ++K ++ Sbjct: 495 SNKNYDELLK-----DSSSKRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKIKNVLMH 549 Query: 523 PLG-KHHFENVSIE 535 +G K+ ++ + IE Sbjct: 550 SIGAKYDYKKMRIE 563 >5IPW-A nrPDB Length = 633 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 37/119 (31%), Positives = 64/119 (53%), Gaps = 21/119 (17%) Query: 62 NRLVEFKIGTTE-----VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNAD 116 ++L+E K+ + ++PGLA+ WEV E+G+ Y FHLRKGVKW D + A Sbjct: 77 SKLIEVKLAFWDKEGGKLVPGLAKSWEVLENGRVYIFHLRKGVKWSDGAPY------TAH 130 Query: 117 DVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFL 175 D+VF + + ++ +++ +G+ +V+ +DD TV+F ++P FL Sbjct: 131 DIVFWVNDIVGNDD----ITPSKPDWY-NIGV-----KVEALDDYTVKFEFSKPYGLFL 179 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 69/147 (46%), Gaps = 11/147 (7%) Query: 299 VQKKPLDDVKVRQALTYAVNKDAIIKAVYQG-AGVSAKNLIPPTMWGYNDDVQDYT-YDP 356 V +K +DV+ RQAL+ A+N++ I + ++ G A +L+ + + + + Y YDP Sbjct: 351 VLRKVFNDVRFRQALSLAINREEINEILFNGLAEPRQASLVSGSPYFDPEWEKAYAEYDP 410 Query: 357 EKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAE-------MIQADWAKVGVQAKI 409 ++A LL E GL+ + +P RP + M++ W ++GV +I Sbjct: 411 DRANKLLDEMGLKWDDKHEYRLLPDGRPLRFTITVTGQFHVDVWTMVKEYWKQIGVWVEI 470 Query: 410 VTYEWGEYLKRAKDGEHQTVMMGWTGD 436 E + +RA G+ M W D Sbjct: 471 ENLERSLFYERADAGDFDA--MVWNMD 495 >4ONY-A nrPDB Length = 595 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 86/415 (20%), Positives = 162/415 (39%), Gaps = 92/415 (22%) Query: 78 LAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFD-RQKNAQNPYHKVS 136 LAEK + + K F L KW D + + DDV+F++D + + PY+ Sbjct: 102 LAEKVAIDPERKWVEFTLNPKAKWSDGQP------VTVDDVLFTYDILTEKGRPPYNSRM 155 Query: 137 GGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRP---EAPFLADLAMDFASILSKEYADA 193 +++++K + +V+F E P L +M +L K A Sbjct: 156 -------------SRVAKIEKTGERSVRFTFNEKSDREFPMLIAGSM---PVLPKH---A 196 Query: 194 MMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-------PQIDTLVFSI 246 + + PIG+GP+ + Q RI YK YWG D + Sbjct: 197 INRDTFGNSTLEPPIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEY 256 Query: 247 TPDASVRYAKLQKNECQVMPYPNPA------DIARMKQDKSI-NLME--MPGLNVGYLSY 297 + + + +K + NP D ++Q K I + E P +G++ + Sbjct: 257 YRNETSLFESFKKGILDIFIEGNPIRWEKLYDFPAVEQGKVIKDTFEKGTPADMLGFV-F 315 Query: 298 NVQKKPLDDVKVRQAL--------------------TYAVNKDAIIKAVYQGAGVSAKNL 337 N ++ D +VRQAL T + + + + +V + A + L Sbjct: 316 NTRRPIFADRRVRQALGLLFDFEWANSNLFAGQYRRTQSFWEGSQLSSVGRPADAREREL 375 Query: 338 IPPTMWGYNDDVQDYTYDP-------------EKAKALLKEAGLE--KGFSIDLWAMPVQ 382 + P +DV + T+ P +KA LL +AG + G +ID P Sbjct: 376 LAPFPGAVREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAID----PTA 431 Query: 383 RPY-------NPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVM 430 +P+ +P+ ++A Q + +++G+ +I T + +Y +R + ++ ++ Sbjct: 432 KPFAFEIMTRSPDEEKIALAYQRNLSRLGIAVEIHTVDDAQYQQRLQTFDYDMIL 486 >3I5O-A nrPDB Length = 592 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 99/499 (19%), Positives = 186/499 (37%), Gaps = 89/499 (17%) Query: 60 LYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVV 119 +Y ++ +G IP +AE++E +D KT ++R +W D + ADD V Sbjct: 39 MYLPAFQYDLGRDAWIPVIAERYEFVDD-KTLRIYIRPEARWSDGVP------ITADDFV 91 Query: 120 FSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLA 179 ++ + K ++ G G G I VK VD V+F + L+ Sbjct: 92 YALELTK-------ELGIGP-----GGGWDTYIEYVKAVDTKVVEFKAKEENLNYFQFLS 139 Query: 180 MDFASILSKEYADAMMKAGTPEKLDLN-----PIGTGPFQLQQYQKDSRIRYKAFDGYWG 234 + ++ ++A K +N + +GP++L Y + + Y+ D +WG Sbjct: 140 YSLGAQPMPKHVYERIRAQMNIKDWINDKPEEQVVSGPYKLYYYDPNIVV-YQRVDDWWG 198 Query: 235 T------KPQ-IDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEM 287 +P+ + +++ P AS+ + + D + L E Sbjct: 199 KDIFGLPRPKYLAHVIYKDNPSASLAFER------------GDIDWNGLFIPSVWELWEK 246 Query: 288 PGL---------------NVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGV 332 GL VG++ N K L D VR+A+ YA+ + ++K Y G G Sbjct: 247 KGLPVGTWYKKEPYFIPDGVGFVYVNNTKPGLSDPAVRKAIAYAIPYNEMLKKAYFGYGS 306 Query: 333 SAKNLIPPTMWGYNDDVQDYT--------------YDPEKAKALLKEAGLEKG------- 371 A + ++ DY +D + A +L EAG +KG Sbjct: 307 QAHPSMVIDLFEPYKQYIDYELAKKTFGTEDGRIPFDLDMANKILDEAGYKKGPDGVRVG 366 Query: 372 -FSIDLWAMPVQRPYN-PNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTV 429 L + PY + M EMI + +G+ K ++ + R G + Sbjct: 367 PDGTKLGPYTISVPYGWTDWMMMCEMIAKNLRSIGIDVKTEFPDFSVWADRMTKGTFDLI 426 Query: 430 MMGWTGDNGD-PDNFFATLFSCAASE------QGSNYSKWCYKPFEDLIQPARATDDHNK 482 + G + D P N + + S+ ++ ++ +L+ A +T D Sbjct: 427 ISWSVGPSFDHPFNIYRFVLDKRLSKPVGEVTWAGDWERYDNDEVVELLDKAVSTLDPEV 486 Query: 483 RVELYKQAQVVMHDQAPAL 501 R + Y + Q +++ P++ Sbjct: 487 RKQAYFRIQQIIYRDMPSI 505 >5ICQ-A nrPDB Length = 610 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 22/162 (13%) Query: 74 VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYH 133 + P +A+ ++ TFHL + D K + A+DV+FSFD K P Sbjct: 110 LYPLIAQSIDIDPARTRVTFHLDPRAHFSDGKP------ITAEDVLFSFDLLKAKGRPQQ 163 Query: 134 KVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADA 193 +++ G + + ++ V D + +L P L A+D + ++DA Sbjct: 164 RIAYGLVKSATAPDPHRVAYDLTGVGDRELPLILA--IMPVLPKHALDV-----ERFSDA 216 Query: 194 MMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT 235 + P+G+GP+ + Q +R+ K YWG Sbjct: 217 TLA---------KPLGSGPYVVADVQAGARLLLKRDPNYWGA 249 >3WE0-A nrPDB Length = 580 Score = 31.6 bits (70), Expect = 0.95, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Query: 197 AGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAK 256 AG +L +G P + + R+R +AF+G G ++ + F ++ A Y Sbjct: 76 AGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHY-- 133 Query: 257 LQKNECQVMPYPNP 270 + K + P+PNP Sbjct: 134 VDKLGLETKPFPNP 147 >2CWD-A nrPDB Length = 161 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 3/38 (7%) Query: 360 KALLKEAGLEKGFSID---LWAMPVQRPYNPNARRMAE 394 + LLKE GLE F +D A V P +P ARR+ E Sbjct: 26 RKLLKERGLEDRFEVDSAGTGAWHVGEPMDPRARRVLE 63 >1V8F-A nrPDB Length = 276 Score = 29.6 bits (65), Expect = 3.9, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 23/42 (54%) Query: 332 VSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFS 373 V + P +G +D Y D E+ +ALL+EAG++ F+ Sbjct: 46 VVVSVFVNPLQFGPGEDYHRYPRDLERDRALLQEAGVDLLFA 87 >2XCU-A nrPDB Length = 374 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 315 YAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSI 374 Y V K AI+ + G NL+ PT WG YT+ K L++ G GF + Sbjct: 275 YPVGKIAIVGGTFVNIG--GHNLLEPTCWGIPVIYGPYTHKVNDLKEFLEKEG--AGFEV 330 >5AFO-A nrPDB Length = 362 Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 106 EFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYF 143 ++ P R + D +F KN QNP V+G +Y F Sbjct: 2 DWGPCRTASGDPFIFVTSFTKNIQNPTDNVTGQTYPDF 39 >5WQW-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 437 NGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATD 478 N N+ +L +Q +N S + Y FE I PA+AT+ Sbjct: 17 NASKTNYGVSLNEYIKLQQRNNPSNYSYSEFEKYINPAKATN 58 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5F1Q-A nrPDB 670 0.0 1DPE-A nrPDB 654 0.0 3TPA-A nrPDB 547 e-156 3M8U-A nrPDB 542 e-154 4QFK-H nrPDB 518 e-147 5U4O-A nrPDB 447 e-126 3TCF-A nrPDB 430 e-121 1OLA-A nrPDB 427 e-120 2Z23-A nrPDB 421 e-118 6DQU-A nrPDB 396 e-110 3MW0-A nrPDB 390 e-109 3O9P-A nrPDB 383 e-106 4OER-A nrPDB 382 e-106 1UQW-A nrPDB 370 e-103 6HLX-A nrPDB 359 2e-99 4GL8-A nrPDB 347 6e-96 3ZS6-A nrPDB 345 2e-95 1XOC-A nrPDB 344 4e-95 5YH8-A nrPDB 335 3e-92 4OEU-A nrPDB 334 6e-92 4PFT-A nrPDB 332 2e-91 5ISU-A nrPDB 331 4e-91 4PFU-A nrPDB 329 2e-90 3T66-A nrPDB 316 2e-86 4ZE8-A nrPDB 310 8e-85 5KZT-A nrPDB 300 1e-81 6NPO-A nrPDB 297 1e-80 4WED-A nrPDB 295 3e-80 3I5O-A nrPDB 282 2e-76 4FAJ-A nrPDB 280 8e-76 5ZA4-A nrPDB 278 5e-75 1ZTY-A nrPDB 278 5e-75 5YQW-A nrPDB 277 9e-75 2WOP-A nrPDB 272 2e-73 4XKN-A nrPDB 270 1e-72 4OFL-A nrPDB 243 1e-64 4ONY-A nrPDB 237 1e-62 3DRH-A nrPDB 236 2e-62 2D5W-A nrPDB 225 4e-59 6EQ0-A nrPDB 213 1e-55 5IPW-A nrPDB 208 4e-54 5ICQ-A nrPDB 190 1e-48 Sequences not found previously or not previously below threshold: 2GRV-A nrPDB 111 7e-25 4YRY-B nrPDB 35 0.092 1NW1-A nrPDB 34 0.25 4JZB-A nrPDB 33 0.26 6AH3-B nrPDB 33 0.35 3UE3-A nrPDB 32 0.48 5JFC-L nrPDB 32 0.53 5JOS-A nrPDB 32 0.57 2NMV-A nrPDB 32 0.57 2NVK-X nrPDB 32 0.67 1D9Z-A nrPDB 32 0.67 2GLJ-A nrPDB 32 0.84 5OL2-B nrPDB 32 0.91 4YMX-A nrPDB 31 1.4 5TUJ-C nrPDB 31 1.8 6E39-A1 nrPDB 31 1.9 4Q10-A nrPDB 30 2.2 5ZJU-A nrPDB 30 2.2 1I43-A nrPDB 30 2.9 3R0R-A nrPDB 30 3.4 1MC8-A nrPDB 29 4.2 4ZV2-A nrPDB 29 4.2 6DZU-A1 nrPDB 29 5.4 5C30-A nrPDB 29 7.6 >5F1Q-A nrPDB Length = 543 Score = 670 bits (1729), Expect = 0.0, Method: Composition-based stats. Identities = 454/535 (84%), Positives = 504/535 (94%) Query: 1 MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPL 60 M ISL+++G+LK G+ LVA+T+AASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVP+ Sbjct: 1 MTISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPI 60 Query: 61 YNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVF 120 YNRLVEFKIGTTE+ P LAE+WEVSEDGKTYTF+LRKGVKW DNK+FKPTR+ NADDV++ Sbjct: 61 YNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIY 120 Query: 121 SFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAM 180 SF RQK+ +NPYHKVSGGSYEYF+GMG+ +LI+ V KVDDNTV+F LTRPE+PFLADLAM Sbjct: 121 SFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAM 180 Query: 181 DFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQID 240 DFASILS EYAD M+KAGTPEK+DLNPIGTGPFQLQQYQKDSRI YKAF G+WGTKP+ID Sbjct: 181 DFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID 240 Query: 241 TLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQ 300 LVFSITPDASVRYAKLQKNECQ+MPYPNPADIARMK+DK+INLME PGLNVGYLS+N++ Sbjct: 241 RLVFSITPDASVRYAKLQKNECQIMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIE 300 Query: 301 KKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAK 360 KKPLD++KVRQALT AVNKDAII AVYQGAG +AKNLIPPTMWGYNDDV+DY YDP KAK Sbjct: 301 KKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAK 360 Query: 361 ALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKR 420 LLKEAGL GFSIDLWAMPVQRPYNPNARRMAEMIQ+DWAK+GV+AKIVTYEWGEYLKR Sbjct: 361 ELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKR 420 Query: 421 AKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDH 480 AKDGEH+TVMMGWTGDNGDPDNFFATLFSC A++QGSNYSKWCYKPFEDLIQPARA DH Sbjct: 421 AKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH 480 Query: 481 NKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 +KRV LYKQAQVVM++QAPALIIAHSTV+EPVRKEVKGYVVDPLGKHHF+NVS++ Sbjct: 481 DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD 535 >1DPE-A nrPDB Length = 507 Score = 654 bits (1687), Expect = 0.0, Method: Composition-based stats. Identities = 505/507 (99%), Positives = 505/507 (99%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 KTLVYCSEGSPEGFNPQLF SGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG Sbjct: 1 KTLVYCSEGSPEGFNPQLFISGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 60 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 148 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL Sbjct: 61 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 120 Query: 149 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 208 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI Sbjct: 121 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 180 Query: 209 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 268 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP Sbjct: 181 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 240 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ Sbjct: 241 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 300 Query: 329 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 388 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN Sbjct: 301 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 360 Query: 389 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLF 448 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFAT F Sbjct: 361 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATEF 420 Query: 449 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV Sbjct: 421 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 480 Query: 509 FEPVRKEVKGYVVDPLGKHHFENVSIE 535 FEPVRKEVKGYVVDPLGKHHFENVSIE Sbjct: 481 FEPVRKEVKGYVVDPLGKHHFENVSIE 507 >3TPA-A nrPDB Length = 521 Score = 547 bits (1409), Expect = e-156, Method: Composition-based stats. Identities = 260/511 (50%), Positives = 332/511 (64%), Gaps = 1/511 (0%) Query: 25 SVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEV 84 S TLV C +P +P + ++ASS +YNRLVEFK G EV PGLAE+WE+ Sbjct: 4 SAPTNTLVNCIATAPMKLSPAITNDANDFNASSQQVYNRLVEFKAGKIEVEPGLAERWEI 63 Query: 85 SEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFE 144 SEDG YTF+LR+ VK+H NK F PTR LNADDVVFSF RQ + +PYH VS G+Y YF Sbjct: 64 SEDGLVYTFYLRQNVKFHSNKTFSPTRPLNADDVVFSFQRQADKNHPYHNVSAGTYFYFN 123 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 M LP ++ V+KVDD TV+ L +P PF+ +AMDF SI SKEYAD ++ G PE LD Sbjct: 124 WMNLPSILKSVEKVDDYTVKITLNKPNTPFITTVAMDFLSIYSKEYADQLLAQGKPETLD 183 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQV 264 PIGTGPF Q Q D +RY A YW K I+ L+FSITPDA RYAKL+ EC V Sbjct: 184 QQPIGTGPFIFQTNQTDHAVRYTANVDYWKGKADIERLIFSITPDAGTRYAKLKAGECDV 243 Query: 265 MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIK 324 + +PN +DIA+MK+D INL+E GLN+ Y+ N K L++VKVRQAL +A +K AI+ Sbjct: 244 IDFPNISDIAQMKKDPQINLLEREGLNLAYIGLNTTKPELNNVKVRQALHHATDKKAIVD 303 Query: 325 AVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRP 384 AVYQG G A N P + GYN + Y ++ EKAKALL EAG GF ++W PV RP Sbjct: 304 AVYQGGGTVATNPFPDAVLGYNPHLPQYEFNLEKAKALLAEAGYPNGFETEIWVQPVVRP 363 Query: 385 YNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFF 444 NPN RR AE+IQADWAK+GV+AK+VT+EW ++ KR ++GE GWT NGDPDNF Sbjct: 364 SNPNPRRTAEIIQADWAKIGVKAKLVTHEWADFNKRTREGEFAAGTYGWTSRNGDPDNFL 423 Query: 445 ATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIA 504 LFS A+ G+NYS+W + FE L+ A D R +LY+QA + +P + A Sbjct: 424 FPLFS-QANIPGTNYSRWTDEKFEALLASAAQIQDTQTRAKLYQQAVEIFQQNSPIIPFA 482 Query: 505 HSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 HS + P+ K V+G+V +P G F VS++ Sbjct: 483 HSINYVPLNKRVQGFVQNPFGYTAFYGVSLK 513 >3M8U-A nrPDB Length = 522 Score = 542 bits (1395), Expect = e-154, Method: Composition-based stats. Identities = 265/506 (52%), Positives = 344/506 (67%), Gaps = 1/506 (0%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 KT + C SP GF+P L G +Y+ASS +YNRLVEFK G+T++ P LAE W VS+DG Sbjct: 3 KTFINCVSRSPTGFSPALVMDGISYNASSQQVYNRLVEFKRGSTDIEPALAESWTVSDDG 62 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 148 TYTF+LRKGVK+H NKEF P+R+ NADDVVFSF RQ + +PYH VS +Y YF+ M Sbjct: 63 LTYTFNLRKGVKFHSNKEFTPSRDFNADDVVFSFQRQLDPNHPYHNVSKATYPYFKAMKF 122 Query: 149 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 208 L+ V+KVD +TV+ L R +A FLA L MDF SI S EYAD M+ AG PE +D PI Sbjct: 123 STLLKSVEKVDMHTVKITLNRQDATFLASLGMDFISIYSAEYADKMLAAGKPETIDTTPI 182 Query: 209 GTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYP 268 GTGPF YQ D + RY A YW K ID L+F I PDA+ RYAKLQ C ++ +P Sbjct: 183 GTGPFLFAGYQVDQKSRYLAHKEYWKGKADIDRLIFEIVPDATARYAKLQAGACDLIDFP 242 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQ 328 N AD+ +MK D +NL GLN+ Y+++N +K P D+VKVRQAL YAV+K+AII AVY+ Sbjct: 243 NAADLEKMKTDPKVNLHSQSGLNIAYIAFNTEKAPFDNVKVRQALNYAVDKNAIIDAVYR 302 Query: 329 GAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPN 388 GAGV+AKN +PPT+WGYN+++ Y Y PEKAK LLKEAG E GF D+W PV R NPN Sbjct: 303 GAGVAAKNPLPPTIWGYNNEITGYEYSPEKAKQLLKEAGFENGFETDIWVQPVVRASNPN 362 Query: 389 ARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLF 448 RRMAE++Q+DW KVGV++K+V+YEWG+Y+KR K GE GW+GDNGDPDNF + LF Sbjct: 363 PRRMAELVQSDWEKVGVKSKLVSYEWGDYIKRTKAGELTAGTYGWSGDNGDPDNFLSPLF 422 Query: 449 SCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 + + SNY+++ + L+ A D +R ++Y+QAQV++ +QAP + +AHS Sbjct: 423 G-SENVGNSNYARFKNPELDALLHKAVGLSDKAERAKIYEQAQVLLKEQAPWINVAHSIN 481 Query: 509 FEPVRKEVKGYVVDPLGKHHFENVSI 534 F P K V+ Y P G + + Sbjct: 482 FAPTSKRVQDYKQSPFGYTYLYGTKL 507 >4QFK-H nrPDB Length = 541 Score = 518 bits (1334), Expect = e-147, Method: Composition-based stats. Identities = 211/507 (41%), Positives = 313/507 (61%) Query: 27 QAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSE 86 + + LVYC+E +P FNPQ+ T+G+T D + LY+RL+ T E LA W++S+ Sbjct: 27 KNQGLVYCAEANPVSFNPQVTTTGSTIDIIANQLYDRLISIDPVTAEFKSELATDWKISK 86 Query: 87 DGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGM 146 DGK+ TF LRKGVK+H F PTRE NADDV+F+F R + NPYH V +Y YF+ + Sbjct: 87 DGKSVTFTLRKGVKFHTTAYFTPTREFNADDVIFTFSRLFDVYNPYHFVGDANYPYFQSV 146 Query: 147 GLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLN 206 G+ +LI ++ +V D+ V+F L E+ FLA++A DFA +LSKEYA A+ D Sbjct: 147 GIDQLIRKIVRVSDHQVRFELFNAESSFLANMATDFAVVLSKEYAMALKANNQENLFDQY 206 Query: 207 PIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMP 266 P+GTGP+ ++Y++D +R+ YW + ++ LV+ ITP+ + R AK+ EC V Sbjct: 207 PVGTGPYIYKEYRRDHLVRFYKNADYWKHEVALEQLVYDITPNGTTRIAKILTKECDVTA 266 Query: 267 YPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAV 326 +P+ A ++ + Q IN+ LN+GY ++N ++ P D++KVRQAL +A++ + I++AV Sbjct: 267 HPSSAQLSILAQRDDINVERETNLNIGYWAFNTERPPFDNLKVRQALVHAIDIEKIMQAV 326 Query: 327 YQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYN 386 Y G G+ A++++PPT W + +DP+ AK LL EAG EKGF + +WAMPV R YN Sbjct: 327 YYGNGLRARSILPPTSWAFEPQKNMPIFDPQLAKKLLTEAGYEKGFDMSIWAMPVSRIYN 386 Query: 387 PNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFAT 446 PNAR+MAE++Q+D K+GV IV YEW +++R + H +V++GW D DPDNFF+ Sbjct: 387 PNARKMAELMQSDLRKIGVNVNIVEYEWNTFIQRIGEHRHDSVLLGWAADTPDPDNFFSP 446 Query: 447 LFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHS 506 L SC A+ G N + WC F+ L+ A T D N R + Y AQ ++ +Q P IAH Sbjct: 447 LLSCTATFSGKNPANWCNPEFDLLLTKALDTTDLNLRKQYYDAAQSMIIEQLPLYPIAHG 506 Query: 507 TVFEPVRKEVKGYVVDPLGKHHFENVS 533 F+ +V+G + P G N Sbjct: 507 MRFQASSADVEGITLGPFGAISLANAR 533 >5U4O-A nrPDB Length = 521 Score = 447 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 153/547 (27%), Positives = 254/547 (46%), Gaps = 47/547 (8%) Query: 7 KSGMLKLGLSLVAMTV---AASVQAKT--LVYCSEGSPEG-------------FNPQLFT 48 K G++ ++++ ++V S AKT S+G+ EG +P T Sbjct: 4 KRGLVSCFIAILCLSVFLAGCSSNAKTGNEGSGSKGTKEGGVLTIARLSDADNLDPHFIT 63 Query: 49 SGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFK 108 + + +Y LV+ + P LA++W+ +D + F L++GV + D F Sbjct: 64 NIPSASVVYHKVYENLVQRD-KNMDFKPMLAKEWKQIDD-LNWEFKLQQGVTFQDGAPF- 120 Query: 109 PTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLT 168 NA+ V +F+R + + ++ + + +I E+K +D+ TVQF+L Sbjct: 121 -----NAEAVKKNFERVLDPKVGSNRAT-----------VYSMIQEIKVIDEYTVQFILK 164 Query: 169 RPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKA 228 P +P L+ A + SILS + D K L +P+GTGP+ + ++ IR + Sbjct: 165 YPYSPLLSIFASNEGSILSPKAIDEKGK-----GLAQHPVGTGPYTFKSWKPGEEIRLEK 219 Query: 229 FDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMP 288 YWG K ++D +VF + P+ + R ++ +E + ++ R+K S+ L+E Sbjct: 220 NKNYWGEKAKVDEVVFKVVPEDATRIGMIETSEAHIAENLPVTEVERVKNSPSMELIENE 279 Query: 289 GLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDD 348 GL V Y+ +NV+KKP D+ VRQA+ +A+ I+K VY G +++ P ++GY D Sbjct: 280 GLGVEYIGFNVEKKPFDNPLVRQAIAHAIETKGILKGVYNNVGTEINSVMTPKVFGYTKD 339 Query: 349 VQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAK 408 V+ Y YD AK LL +AG GF +W + + E+IQ+ +GV + Sbjct: 340 VKGYKYDINTAKKLLADAGYPNGFKTTIWT-----NDSKVRMALVEVIQSQLKGIGVDVE 394 Query: 409 IVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFE 468 I E+G +L EH + GW GD D LF ++ N + + Sbjct: 395 IKVMEYGAFLAATNKSEHAMFVGGWGNATGDGDYNQYNLFHSSSHGATGNQFFYSNPEVD 454 Query: 469 DLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHH 528 LI+ AR D KR ELYKQ Q + A + I K +KG+ +DP G Sbjct: 455 KLIEEARKEKDETKRKELYKQLQEIELKDALLVPIRGINHIAATTKNIKGFWIDPSGYLR 514 Query: 529 FENVSIE 535 E V ++ Sbjct: 515 LEGVELQ 521 >3TCF-A nrPDB Length = 524 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 121/524 (23%), Positives = 205/524 (39%), Gaps = 34/524 (6%) Query: 26 VQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 + +TLV + + +P G S L+ L+ + PG+AE W+ + Sbjct: 11 AEKQTLVRNNGSEVQSLDPHKI-EGVPESNISRDLFEGLLVSDLDG-HPAPGVAESWD-N 67 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEG 145 +D K +TFHLRK KW D + A D V+S+ R + S Y + G Sbjct: 68 KDAKVWTFHLRKDAKWSDGTP------VTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 121 Query: 146 MG------LPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGT 199 + P VK +DD+T++ L+ P F L S + K A+ K G Sbjct: 122 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA---AIEKFGE 178 Query: 200 PEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKLQ 258 N + G + L+ + + RI + YW K I+ + + + + Sbjct: 179 KWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYR 238 Query: 259 KNECQVMPYPNPAD-IARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 E + P + ++K++ + P L Y N QK P +DV+VR AL + Sbjct: 239 SGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGM 298 Query: 318 NKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDP-----EKAKALLKEAGLEKGF 372 ++D I+ V + A PP G ++ E+AK LL EAG Sbjct: 299 DRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADK 358 Query: 373 SIDLWAMPVQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVMM 431 + + + +++A + W K +GV K+V EW +L G Sbjct: 359 PLTINLLYNTSDL---HKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARA 415 Query: 432 GWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQ 491 GW D +P +F T+ S + N + + F+ ++ D +R LY +A+ Sbjct: 416 GWCADYNEPTSFLNTMLSNS----SMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAE 471 Query: 492 VVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 + + + + + V+ V GY DPL + N+ I Sbjct: 472 QQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYI 515 >1OLA-A nrPDB Length = 517 Score = 427 bits (1097), Expect = e-120, Method: Composition-based stats. Identities = 123/524 (23%), Positives = 207/524 (39%), Gaps = 34/524 (6%) Query: 26 VQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 +TLV + + +P G S L+ L+ + PG+AEKWE + Sbjct: 10 ADKQTLVRNNGSEVQSLDPHKI-EGVPESNVSRDLFEGLLISDV-EGHPSPGVAEKWE-N 66 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEG 145 +D K +TFHLR+ KW D + A D V+S+ R + S Y + Sbjct: 67 KDFKVWTFHLRENAKWSDGTP------VTAHDFVYSWQRLADPNTASPYASYLQYGHIAN 120 Query: 146 MG------LPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGT 199 + P VK +DD+T + L+ P F L S + K A+ K G Sbjct: 121 IDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVSPVPK---SAVEKFGD 177 Query: 200 PEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKLQ 258 N + G ++L+ + + RI + YW K I+ + + + + Sbjct: 178 KWTQPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVTYLPISSEVTDVNRYR 237 Query: 259 KNECQVMPYPNPAD-IARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 E + P + ++K++ + P L Y N QK P +DV+VR AL A+ Sbjct: 238 SGEIDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLAL 297 Query: 318 NKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDP-----EKAKALLKEAGLEKGF 372 ++D I+ V + A + PP G ++ E+AK LL EAG Sbjct: 298 DRDIIVNKVKNQGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADK 357 Query: 373 SIDLWAMPVQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVMM 431 + + +++A + + W K +GV + EW +L G Sbjct: 358 PLTFDLLYNTSDL---HKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARA 414 Query: 432 GWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQ 491 GW D +P +F T+ S + +N + + F+ LI D +R ELY +A+ Sbjct: 415 GWCADYNEPTSFLNTMLS----DSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAE 470 Query: 492 VVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 + + + + + V+ V GY DPL + +N+ I Sbjct: 471 QQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNIYVKNLYI 514 >2Z23-A nrPDB Length = 517 Score = 421 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 117/525 (22%), Positives = 210/525 (40%), Gaps = 36/525 (6%) Query: 26 VQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 + + LV + P+ +P G S L LV ++PG AE W+ + Sbjct: 10 AEKQVLVRNNGSEPQSLDPHKI-EGVPESNISRDLLEGLVINDP-NGNIVPGAAESWD-N 66 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSY----- 140 +D K +TF++RK KW + + A D V+S+ R + + S Y Sbjct: 67 KDFKVWTFNIRKDAKWSNGDP------VTAQDFVYSWQRLADPKTVSPYASYLQYAHLTN 120 Query: 141 --EYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAG 198 + G P+ + VK +DD+T++ L+ P LA S ++K + K G Sbjct: 121 IDDIITGKAAPDTLG-VKALDDHTLEVTLSEPVPYLDKLLAHPLMSPVNKTVVE---KFG 176 Query: 199 TPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKL 257 N +G G ++L+ + + RI + YW K I+ + + + Sbjct: 177 EKWTQPQNFVGNGAYKLKDWIVNERIVLERSPTYWDNAKTVINQVTYLPISSEVTDVNRY 236 Query: 258 QKNECQVMPYPNPAD-IARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYA 316 + E + P + ++K++ + P L Y N QK P D +VR+AL Sbjct: 237 RSGEIDMTYNNMPIELFQKLKKEIPDQVHVDPYLCTYYYEINNQKAPFTDARVREALKLG 296 Query: 317 VNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEK-----AKALLKEAGLEKG 371 +++D I+ V + A PP G ++ ++ AK LL EAG K Sbjct: 297 MDRDIIVNKVKNQGDLPAYGFTPPYTSGAELTPPEWFSWTQEKRNEVAKKLLAEAGYTKD 356 Query: 372 FSIDLWAMPVQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVM 430 + + +++A + W K +GV K+ EW +L G + Sbjct: 357 NPLKFSLLYNTSDL---HKKLAIAAASIWKKNLGVDVKLENQEWKTFLDTRHQGTYDVAR 413 Query: 431 MGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQA 490 W D +P +F + S + +N + + F+ LI+ +R +LY+QA Sbjct: 414 AAWCADYNEPSSFLNMMLSNS----SNNTTHYKSSVFDKLIEDTLKVKSEKERADLYQQA 469 Query: 491 QVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 ++ + + + + + V+ V GY DPL H +++ I Sbjct: 470 EIQLDKDSAIVPVFYYVSARLVKPYVGGYTGKDPLDNMHVKDLYI 514 >6DQU-A nrPDB Length = 530 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 118/538 (21%), Positives = 209/538 (38%), Gaps = 39/538 (7%) Query: 17 LVAMTVAASVQAKT-LVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVI 75 +V + + K +V + P+ F+P T G + L LV ++ Sbjct: 1 MVIVPEGTQLDEKQHIVINNGAEPQSFDPHK-TEGVPESNVAYQLLEGLVTSD-SEGKLQ 58 Query: 76 PGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKV 135 PG AE WE + D KT+TFHLRK KW + + A D VF++ R + Sbjct: 59 PGAAESWENTPDFKTWTFHLRKDAKWSNGDP------VTAHDFVFAWRRLVDPATAAPYA 112 Query: 136 SGGSY-------EYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSK 188 S SY + +G P + V+ DD T T P ++ L + Sbjct: 113 SYLSYLQVENAQDIIDGKKKPAELG-VEAKDDYTFVVHATNPVPYAVSLTTHQSLLPLPQ 171 Query: 189 EYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-PQIDTLVFSIT 247 + + K G N +G G ++L + + +I ++ YW K I++ F Sbjct: 172 KVVE---KLGDAWVKKENYVGNGAYKLANHIINEKIEFERNPLYWNDKETVINSATFLAI 228 Query: 248 PDASVRYAKLQKNECQVMPYPNPAD-IARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDD 306 + S A+ + + + Y P + A++K++ + L N +K P D+ Sbjct: 229 ENPSTDVARYRAGDLDMTSYGLPPEQFAKLKKELLGEVYVTRTLGTYSYELNNKKAPFDN 288 Query: 307 VKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMW-GYNDDVQDYTYDP-----EKAK 360 V +R+AL +++++ I V P + G+ Y+ +P E+A Sbjct: 289 VNIRKALNLSLDRNVITDKVLGQGQTPTYVFTPTYIEEGHLIQQPAYSKEPMAQRNEEAI 348 Query: 361 ALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWA---KVGVQAKIVTYEWGEY 417 LL+EAG K + + N N +++A + W K + K+ EW Y Sbjct: 349 KLLEEAGYSKANPLKF---SILYNTNENHKKVAIAAASMWKANTKGLIDVKLENQEWKTY 405 Query: 418 LKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARAT 477 + + G + GW D F S + +N +K+ ++ + + A Sbjct: 406 IDSRRAGRYDVARAGWHADYNQATTFGNYFLSNS----SNNTAKYANPEYDKAMAESYAA 461 Query: 478 DDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 534 D R + Y +A+ ++ + I + V+ VKGY DP + N+ I Sbjct: 462 TDAEGRAKAYAKAEEILGKDYGIVPIFNYVNPRLVKPYVKGYSGKDPQDHIYLRNLYI 519 >3MW0-A nrPDB Length = 502 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 128/498 (25%), Positives = 219/498 (43%), Gaps = 39/498 (7%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKW 101 NP L+T + S +Y LV+++ + VIP LA+ W SEDGKT+TF LR VK+ Sbjct: 17 LNPHLYTPNQMFAQSM--VYEPLVKYQADGS-VIPWLAKSWTHSEDGKTWTFTLRDDVKF 73 Query: 102 HDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDN 161 + + F E A++ D + + + L I +VK + Sbjct: 74 SNGEPFD--AEAAAENFRAVLD---------------NRQRHAWLELANQIVDVKALSKT 116 Query: 162 TVQFVLTRPEAPFLADLAMD--FASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQ 219 +Q L PFL +LA+ F I ++ + G PIGTGP+ LQ+ + Sbjct: 117 ELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKA-----PIGTGPWILQESK 171 Query: 220 KDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVM---PYPNPAD-IAR 275 + + + YWG KP I + F++ PD + R + + ++ P D AR Sbjct: 172 LNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFAR 231 Query: 276 MKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAK 335 Q+ + + + L+ N K P +++ VR+AL YAVNK ++I G A Sbjct: 232 FSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVAD 291 Query: 336 NLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDL-----WAMPVQRPY---NP 387 L P++ N ++ YDP+KAKALL++AG D+ + ++ + + Sbjct: 292 TLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDA 351 Query: 388 NARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATL 447 ++ MAE+IQAD ++G ++ E R +DG + G DP F +++ Sbjct: 352 LSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSM 411 Query: 448 FSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHST 507 + ++ + + I AT D +R LY+ +HD+A L I++ + Sbjct: 412 RVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYIS 471 Query: 508 VFEPVRKEVKGYVVDPLG 525 + + E+ P+ Sbjct: 472 MMVVSKPELGNIPYAPIA 489 >3O9P-A nrPDB Length = 519 Score = 383 bits (983), Expect = e-106, Method: Composition-based stats. Identities = 110/524 (20%), Positives = 207/524 (39%), Gaps = 36/524 (6%) Query: 26 VQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 + + LV + P +P G L+ LV E++PG+A +W+ S Sbjct: 14 AEKQELVRHIKDEPASLDPAKA-VGLPEIQVIRDLFEGLVNQNEKG-EIVPGVATQWK-S 70 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQ--NPYHKVSG-----G 138 D + +TF LR KW D + A D V+S+ R + + +P+ + Sbjct: 71 NDNRIWTFTLRDNAKWADGTP------VTAQDFVYSWQRLVDPKTLSPFAWFAALAGINN 124 Query: 139 SYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAG 198 + +G P+ + V VD +T++ L +P P+ +L +FA ++ A +++G Sbjct: 125 AQAIIDGKATPDQLG-VTAVDAHTLKIQLDKP-LPWFVNLTANFAFFPVQK---ANVESG 179 Query: 199 TPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKL 257 N IG G + L++ + ++ YW K + + F S + Sbjct: 180 KEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRY 239 Query: 258 QKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 + + ++ +D + P L Y ++N QK P D +VR AL+ + Sbjct: 240 LAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTI 299 Query: 318 NKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEK-----AKALLKEAGLEKGF 372 ++ + + V A + P G+ + + ++ AK LL AG Sbjct: 300 DRRLMTEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQK 359 Query: 373 SIDLWAMPVQRPYNPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVMM 431 + L + + N +++A + + W K +GV K+ EW Y+ G + Sbjct: 360 PLKLTLL---YNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRA 416 Query: 432 GWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQ 491 W GD +P F L S N S++ ++ ++ A + R Y A+ Sbjct: 417 SWVGDYNEPSTFLTLLTST----HSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAE 472 Query: 492 VVMHDQAPALIIAHSTVFEPVRKEVKGYVV-DPLGKHHFENVSI 534 ++ +QAP I T ++ +KGY + +P + + I Sbjct: 473 KILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYI 516 >4OER-A nrPDB Length = 500 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 120/493 (24%), Positives = 196/493 (39%), Gaps = 39/493 (7%) Query: 42 FNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKW 101 NP L++ + + +Y LV + T V P LAE WE S+DG++YTF LR+ VK+ Sbjct: 15 LNPHLYSPNQMFAQNM--VYEPLVHYNADGT-VGPWLAESWEASQDGRSYTFKLREDVKF 71 Query: 102 HDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDN 161 + + F A V + D P H + L + + V Sbjct: 72 SNGEVFD------AAAVKANIDTVL-QNRPRH----------NWLELVNQMVSAEVVGPY 114 Query: 162 TVQFVLTRPEAPFLADLAMD--FASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQ 219 V+ L +P P L +L++ F I ++ + G + PIGTGP++L + + Sbjct: 115 KVRINLKKPYYPLLQELSLPRPFRFIAPSQFKNGGTADGI-----VAPIGTGPWKLTETK 169 Query: 220 KDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPY----PNPADIAR 275 + D YWG KP + + + PD + R + E ++ +P R Sbjct: 170 LGEHDVFTRNDSYWGPKPAYEQITVKVIPDPNTRAIAFEAGEIDLIYGTEGPISPDTFER 229 Query: 276 MKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAK 335 ++ N L L+ N D+ VR+A+ +AV+KD +I V G A Sbjct: 230 FQKMGIYNTELSEPLETRVLALNTNHGATKDLAVRKAINHAVDKDTMIATVLYGTQKRAD 289 Query: 336 NLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQ--------RPYNP 387 L + N ++ Y +DP A LL EAG S D+ Q + Sbjct: 290 TLFADNVPYANIGLKPYAFDPALAARLLDEAGWTAKASGDIREKDGQPLAIELCFIGTDA 349 Query: 388 NARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATL 447 ++ MAE++QAD KVG+ K+ E R +DG + G DP F +++ Sbjct: 350 ISKSMAEIVQADLRKVGIDVKLTGEEESSIYARQRDGRFDMIFNQTWGAPYDPHAFVSSM 409 Query: 448 FSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHST 507 + ++ + + I + D R LYK +H++A L + T Sbjct: 410 RVPSHADYQAQLGLPDKAKIDAEIGQVLVSTDETARQALYKDILTRLHEEAVYLPLTSVT 469 Query: 508 VFEPVRKEVKGYV 520 + EV Sbjct: 470 AMAVAKPEVGKIT 482 >1UQW-A nrPDB Length = 509 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 136/515 (26%), Positives = 241/515 (46%), Gaps = 36/515 (6%) Query: 28 AKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSED 87 AK +V + +P + A + Y L ++ LAE + VS+D Sbjct: 24 AKDVVVAVGSNFTTLDPYDANDTLS-QAVAKSFYQGLFGLD-KEMKLKNVLAESYTVSDD 81 Query: 88 GKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMG 147 G TYT LR+G+K+ D +F NA V + DR + N + + Sbjct: 82 GITYTVKLREGIKFQDGTDF------NAAAVKANLDRASDPAN-----------HLKRHN 124 Query: 148 LPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNP 207 L + I++ + +D TV+ L +P + F+ LA +++S + K ++ P Sbjct: 125 LYKNIAKTEAIDPTTVKITLKQPFSAFINILAHPATAMISPAALEKYGK-----EIGFYP 179 Query: 208 IGTGPFQLQQYQKDSRIRYKAFDGYWGTK-PQIDTLVFSITPDASVRYAKLQKNECQVMP 266 +GTGP++L + + ++ K F GYW P++D++ + D + R A LQ E Q Sbjct: 180 VGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQFAF 239 Query: 267 YPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAV 326 ++++K+I LM P + Y+S NV +KP D+ KVR+AL YA+N+ A++K Sbjct: 240 PIPYEQATLLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVA 299 Query: 327 YQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYN 386 + G A ++PP++ Y + + YDP KA+ LLKEAG GFS LW + Sbjct: 300 FAGYATPATGVVPPSI-AYAQSYKPWPYDPVKARELLKEAGYPNGFSTTLW----SSHNH 354 Query: 387 PNARRMAEMIQADWAKVGVQAKIVTYEWGEYL-----KRAKDGEHQTVMMGWTGDNGDPD 441 A+++ + Q A+VG++A++ + G+ K K+ + GW+ G+ D Sbjct: 355 STAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEAD 414 Query: 442 NFFATLFSCAA-SEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPA 500 + LF+ N + + K +D + A T+D ++ LYK AQ ++ ++P Sbjct: 415 WALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPW 474 Query: 501 LIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 + + + K + G+ + P FE+ ++ Sbjct: 475 IPLVVEKLVSAHSKNLTGFWIMPDTGFSFEDADLQ 509 >6HLX-A nrPDB Length = 492 Score = 359 bits (920), Expect = 2e-99, Method: Composition-based stats. Identities = 135/510 (26%), Positives = 228/510 (44%), Gaps = 33/510 (6%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 TL + G P + + GT+ + ++ LV + I ++ P LAE +EVS D Sbjct: 2 GTLYFGLSGEPSTLD-TVVQPGTSGRTVKLAIHRGLVNYGIDG-KISPELAESYEVSPDA 59 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGL 148 K +TFHLR+ K+HD + + DV S +R + + + S Sbjct: 60 KEFTFHLRQ-AKFHDGTT------VTSADVKASLERILDPKGKASFRNELSS-------- 104 Query: 149 PELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPI 208 IS+++ D+ TV+ L+ P + LA+ + I+ A A + + P+ Sbjct: 105 ---ISKIETPDEKTVKLTLSTPSVAMIDYLALPESVIVP-----AAWLAKNADNPNAAPV 156 Query: 209 GTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKLQKNECQVMPY 267 G GPF+ + + I K FD Y+ KP +D + + D + R L+ + ++ Y Sbjct: 157 GAGPFKFAGWTRGREITVKKFDDYYKKGKPDLDEVHYVFYSDENTRVNALKSGDVDIIDY 216 Query: 268 PNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVY 327 D A + + L+ G +G L +N + +P +VRQA+ YAV++ AII + Sbjct: 217 VPAKDAADIAKGPETQLLRNTGPFMG-LQFNTKFEPFSKPEVRQAIAYAVDRSAIINTAF 275 Query: 328 QGAGVSAKNL-IPPTMWGYNDDVQDY-TYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPY 385 G G + IP GY+D +Y ++ EKAKALL +AG GF + L A Q + Sbjct: 276 NGLGSPIFGIAIPKGYMGYSDAKANYFSHHVEKAKALLAKAGYPNGFEVRLLA-TSQYSF 334 Query: 386 NPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFA 445 N A IQ++ AK+G++ K+ +W + +A G++ +MG G+ D D Sbjct: 335 QQN---TAIAIQSELAKIGIKVKLDLPDWASRMAKASTGDYDFTVMGSLGEITDADWLSN 391 Query: 446 TLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAH 505 + + +N + + DL+ RAT D +RV++Y + +P + Sbjct: 392 YYYGGDKLVRTNNSPYFNDQQINDLLDKGRATVDKAERVKIYDAFVDRALELSPLVYFMW 451 Query: 506 STVFEPVRKEVKGYVVDPLGKHHFENVSIE 535 V+K V G+ P +SIE Sbjct: 452 REQNYAVKKGVTGFTNMPGFLTFQSGLSIE 481 >4GL8-A nrPDB Length = 529 Score = 347 bits (891), Expect = 6e-96, Method: Composition-based stats. Identities = 114/492 (23%), Positives = 222/492 (45%), Gaps = 29/492 (5%) Query: 34 CSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTF 93 P + QL T ++ +++ T PGLA+ W++S+DG YTF Sbjct: 35 NIGSEPATLDAQLIND-TVGSGIVSQMFLGILDGDPRTGGYRPGLAKSWDISDDGVVYTF 93 Query: 94 HLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQ------NPYHKVSGGSYEYFEGMG 147 HLR + W D + A+ + S+ R + + N V + EYF+G Sbjct: 94 HLRDNLVWSDGV------SITAEGIRKSYLRILDKETGSSFVNMIKSVIKNAEEYFDGKA 147 Query: 148 LPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNP 207 + +K +D+ T++ L P+ FL L + + K G N Sbjct: 148 NESELG-IKALDEKTLEITLKSPKPYFLDMLVHQTFIPVPMHVIE---KYGQRWTDPENM 203 Query: 208 IGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQ-IDTLVFSITPDASVRYAKLQKNECQVMP 266 + +GPF+L+ + ++ + + Y+ +K +D+++F +T ++ Y +E + Sbjct: 204 VVSGPFKLKSRVLNEKVVLEKNNKYYNSKDVVLDSIIFFVTDNSITAYNMYLNDELDAIF 263 Query: 267 YPNPADIARMKQDKSINLMEMPGLN-VGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKA 325 P D+ +K K + G+N + S N++ KPLD+VKVR+AL++A+++ + ++ Sbjct: 264 KNVPPDL--LKDLKLRDDYYSMGINSTSFYSLNMKVKPLDNVKVRKALSFAIDRKTLTES 321 Query: 326 VYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPY 385 V + + + P + Y+ +D E AK LL +AG G + L + V+ Sbjct: 322 VLNDSSIPTRRATPDYI-DYSYKSNLSLFDAEMAKKLLADAGYPNGNNFPL--LKVKYNT 378 Query: 386 NPNARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFF 444 + + R++AE IQ W K + + ++ EW Y+ +G ++ + GW+GD DP F Sbjct: 379 SDSQRKIAEFIQNQWKKNLNINVQLENEEWSTYINSRVNGNYEIIRSGWSGDYADPMTFL 438 Query: 445 ATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQ-VVMHDQAPALII 503 + + S + +++L+ + D KR E+ K+A+ +++ PA+ + Sbjct: 439 SIFQTENTSFSSYG---YSNSEYDELLIKSDNERDIFKRQEILKKAEAIIIERDFPAVFL 495 Query: 504 AHSTVFEPVRKE 515 ++ R + Sbjct: 496 NITSSSYLFRND 507 >3ZS6-A nrPDB Length = 506 Score = 345 bits (886), Expect = 2e-95, Method: Composition-based stats. Identities = 105/506 (20%), Positives = 188/506 (37%), Gaps = 31/506 (6%) Query: 29 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 88 + L E +P S T + + L+ L + V+PG+A+ WE + Sbjct: 5 QDLTRQVPAEVESLDPAHIESW-TGNTIGLDLFEGLARIDA-SGAVVPGVAQAWE-HKAP 61 Query: 89 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVS----GGSYEYFE 144 T+ F LR+ KW + + + A D V+++ R + + + Sbjct: 62 DTWIFKLRRDAKWSNGQP------VTAADFVYAWQRLADPKTGSKYTILVEFVKNASAII 115 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 P ++ +D T++ P + F AM + ++K DA+ K G Sbjct: 116 AGKQPPGDLGIRAIDPYTIEVKTEVPVSYFPELTAMAPLTPVNK---DAVAKFGDAWTRP 172 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQID-TLVFSITPDASVRYAKLQKNECQ 263 N + GP+ L +Q ++RI D YW + + + + + Q + Sbjct: 173 KNIVSNGPYTLVDWQPNNRIVMAKSDKYWNARNVVIRKVTYLPIENDETALRMYQAGQID 232 Query: 264 VMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAII 323 ++ + L L Y L D +VR+AL ++++ + Sbjct: 233 YTYSIPAGGFGQISKQFGKELRPGLQLATYYYYLKNSDPALKDKRVREALAMVLDREILT 292 Query: 324 KAVYQGAGVSAKNLIPPTMWGYNDDV-QDYTYDP-----EKAKALLKEAGLEKGFSIDLW 377 + Q V L+P + G D+ P + AK LLK+AG + Sbjct: 293 SKITQAGEVPMYGLMPKGVKGVQRPFTPDWASWPMARRVDYAKNLLKQAGHGDANPLTF- 351 Query: 378 AMPVQRPYNPNARRMAEMIQADWA-KVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGD 436 + N +++A ++W K+GV AK+ E+ +K+ DG+ Q GW D Sbjct: 352 --TLTYNTNDLHKKVALFAASEWRTKLGVTAKLENVEFKVLMKQRHDGKVQIARDGWFAD 409 Query: 437 NGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHD 496 D FF L C +S+ N +C + L+ A D R L QA + + Sbjct: 410 YNDAMTFF-DLIRCGSSQ---NTVGYCNPKVDSLVAEANQKLDDGARAALLTQAHDLAMN 465 Query: 497 QAPALIIAHSTVFEPVRKEVKGYVVD 522 P + + + V+ V GY + Sbjct: 466 DYPMVPLFQYSADRLVKSYVGGYTLT 491 >1XOC-A nrPDB Length = 520 Score = 344 bits (883), Expect = 4e-95, Method: Composition-based stats. Identities = 132/518 (25%), Positives = 228/518 (44%), Gaps = 44/518 (8%) Query: 23 AASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTE---VIPGLA 79 Q LV S G P LF S + D +S + N L F T E V LA Sbjct: 16 GKPQQGGDLVVGSIGE-----PTLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLA 70 Query: 80 EKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGS 139 E + + G Y ++KGVK+HD K EL ADDVVF++ + Y G + Sbjct: 71 ESIKELDGGLAYDVKIKKGVKFHDGK------ELTADDVVFTYSVPLSK--DYKGERGST 122 Query: 140 YEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGT 199 Y E++ V+K D V F L + F + A+D +IL K + A Sbjct: 123 Y---------EMLKSVEKKGDYEVLFKLKYKDGNFYNN-ALDSTAILPKHILGNVPIADL 172 Query: 200 PEKL--DLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKL 257 E PIG+GPF+ +++++ I+ +A D Y+ +P +DT+ + + PDA+ A+L Sbjct: 173 EENEFNRKKPIGSGPFKFKEWKQGQYIKLEANDDYFEGRPYLDTVTYKVIPDANAAEAQL 232 Query: 258 QKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 Q + P D ++ ++ ++ L+ Y+ +N + + D KVRQALT A+ Sbjct: 233 QAGDINFFNVP-ATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTAL 291 Query: 318 NKDAIIKAVYQGAGVSAKNLIPPTMWGYND--DVQDYTYDPEKAKALLKEAGLE------ 369 ++++I+ V G G A P W Y DV + Y+ +KAK +L EAG + Sbjct: 292 DRESIVSQVLDGDGEVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDG 351 Query: 370 --KGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAK--DGE 425 N +A ++Q K+G++ K EW +++ + + Sbjct: 352 ILDKDGKKFSFTLKTNQGNKVREDIAVVVQEQLKKIGIEVKTQIVEWSALVEQMNPPNWD 411 Query: 426 HQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVE 485 ++MGW+ PD + +F + ++G NY + + L++ A++ D + + Sbjct: 412 FDAMVMGWSLSTF-PDQY--DIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQYSK 468 Query: 486 LYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDP 523 Y+Q + + P + + + + ++GY P Sbjct: 469 EYEQIYQKIAEDQPYTFLYYPNNHMAMPENLEGYKYHP 506 >5YH8-A nrPDB Length = 510 Score = 335 bits (859), Expect = 3e-92, Method: Composition-based stats. Identities = 129/517 (24%), Positives = 219/517 (42%), Gaps = 47/517 (9%) Query: 20 MTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLA 79 M + + K L Y + NP ++ G + A S+ +Y LV + P LA Sbjct: 3 MGLEEKKENKQLTYTTVKDIGDMNPHVY--GGSMSAESM-IYEPLVRNTKDG--IKPLLA 57 Query: 80 EKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGS 139 +KW+VSEDGKTYTFHLR VK+HD F AD V + D + + Sbjct: 58 KKWDVSEDGKTYTFHLRDDVKFHDGTPFD------ADAVKKNIDAVQENK---------- 101 Query: 140 YEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMD--FASILSKEYADAMMKA 197 + + + LI VK D TV+ L P LA+LAM + + K++ + K Sbjct: 102 -KLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKD 160 Query: 198 GTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKL 257 G + GTGPF+L +++KD + D YWG K +++ + + P + + Sbjct: 161 GVKKFD-----GTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSM 215 Query: 258 QKNECQV-------MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKK--PLDDVK 308 +K E + + ++K + +N L N KK + D Sbjct: 216 KKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKT 275 Query: 309 VRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGL 368 VRQA+ + VN+D I K + G A L + N D+ YD +KA++LL EAG Sbjct: 276 VRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGW 335 Query: 369 EKGFSIDLWAMPVQR--------PYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKR 420 +KG D+ + + + + AE +QA++ K+G++ I + +R Sbjct: 336 KKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAER 395 Query: 421 AKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDH 480 G++ + G DP + A + E ++ + K + I A + Sbjct: 396 RTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNS-IDDAFKIQNG 454 Query: 481 NKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVK 517 +R + YK + D+ + I+H ++ K+++ Sbjct: 455 KERSDAYKNILKQIDDEGIFIPISHGSMTVVAPKDLE 491 >4OEU-A nrPDB Length = 494 Score = 334 bits (856), Expect = 6e-92, Method: Composition-based stats. Identities = 130/514 (25%), Positives = 234/514 (45%), Gaps = 44/514 (8%) Query: 25 SVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEV 84 + TL+ E NP +DA +++ L F + P LA+ W++ Sbjct: 1 KIPKDTLIIAVENEIARINPAY---SEDHDAVINLVFSGLTRFDE-NMSLKPDLAKSWDI 56 Query: 85 SEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFE 144 S+DG Y LR V WHD +F ADDV FS + KN +N + Y F Sbjct: 57 SKDGLVYDIFLRDDVLWHDGVKFS------ADDVKFSIEAFKNPKN-----NSSIYVNF- 104 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 E I V+ ++ + V+ L +P FL L+ +L K + + + Sbjct: 105 -----EDIKSVEILNPSHVKITLFKPYPAFLDALS---IGMLPKHLLEN--ENLNTSSFN 154 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQV 264 NPIGTGP++ +++K + +KA + ++ K + L+ D S+ A+L+ + Sbjct: 155 QNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDA 214 Query: 265 MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIK 324 + + + K D++ ++ + L +N+ + L D+KVRQAL YAV+K++I+K Sbjct: 215 -ALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVK 273 Query: 325 AVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKG----FSIDLWAMP 380 + A + + + W + + + Y YDP+KA+ LL AG +K F D + Sbjct: 274 NLLHDYAFVANHPLERS-WANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILE 332 Query: 381 VQ---RPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDN 437 + +P +A ++Q+++ K+GV +K+V G + + + ++GW G Sbjct: 333 FEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYS----KVDSFLIGW-GSP 387 Query: 438 GDPD----NFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVV 493 DPD F + A +++G N+ + K + +Q AR T + +R + YK Sbjct: 388 LDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDA 447 Query: 494 MHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKH 527 +++ P + +A+ K++KG LG H Sbjct: 448 LYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHH 481 >4PFT-A nrPDB Length = 544 Score = 332 bits (851), Expect = 2e-91, Method: Composition-based stats. Identities = 115/512 (22%), Positives = 205/512 (40%), Gaps = 57/512 (11%) Query: 28 AKTLVYCSE--GSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 KTL + P +NP FT + +Y L + + P LAEK E Sbjct: 6 NKTLYWGGALWSPPSNWNP--FTPWNAVAGTIGLVYEPLFLYDPLNDKFEPWLAEKGEWV 63 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEG 145 + + Y LRKG++W D L ADDVVF+F+ K Y Sbjct: 64 SNNE-YVLTLRKGLRWQDGVP------LTADDVVFTFEIAK------------KYTGISY 104 Query: 146 MGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDL 205 + + +++VD+ T++FV + P + ++ I+ K + + + + Sbjct: 105 SPVWNWLGRIERVDERTLKFVFSDPRYQEWKQMLIN-TPIVPKHIWENKTEEEVLQAANE 163 Query: 206 NPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-----PQIDTLVFSITPDASVRYAKLQKN 260 NP+G+GP+ ++ + D R +K +WG + P+ + +V +V L K Sbjct: 164 NPVGSGPYYVESW-ADDRCVFKKNGNWWGIRELGYDPKPERIVELRVLSNNVAVGMLMKG 222 Query: 261 ECQVMPYPNPADIARMKQDKSINLMEMP-----GLNVGYLSYNVQKKPLDDVKVRQALTY 315 E + P + +K+ I N + NV K PL + R+A+ Y Sbjct: 223 ELDWSNFFLPG-VPVLKKAYGIVTWYENAPYMLPANTAGIYINVNKYPLSIPEFRRAMAY 281 Query: 316 AVNKDAIIKAVYQGAGVSAKN----LIPPTMWGYNDDVQD---YTYDPEKAKALLKEAGL 368 A+N + I+ Y+ +A +P M Y +V D + YDPE AK +L E G Sbjct: 282 AINPEKIVTRAYENMVTAANPAGILPLPGYMKYYPKEVVDKYGFKYDPEMAKKILDELGF 341 Query: 369 ----EKGFSIDLWAMP----VQRPYNPNARRMAEM-IQADWAKVGVQAKIVTYEWGEYLK 419 + GF D P ++ PY ++ I D KVG+ + ++ +Y Sbjct: 342 KDVNKDGFREDPNGKPFKLTIECPYGWTDWMVSIQSIAEDLVKVGINVEPKYPDYSKYAD 401 Query: 420 RAKDGEHQTVMMGW-TGDNGDPDNFFATLFSCAASEQ----GSNYSKWCYKPFEDLIQPA 474 G+ ++ + TG + ++F +F A E N+ K+ E L+ Sbjct: 402 DLYGGKFDLILNNFTTGVSATIWSYFNGVFYPDAVESEYSYSGNFGKYANPEVETLLDEL 461 Query: 475 RATDDHNKRVELYKQAQVVMHDQAPALIIAHS 506 ++D K E+ + ++ P + + ++ Sbjct: 462 NRSNDDAKIKEVVAKLSEILLKDLPFIPLWYN 493 >5ISU-A nrPDB Length = 502 Score = 331 bits (849), Expect = 4e-91, Method: Composition-based stats. Identities = 119/521 (22%), Positives = 219/521 (42%), Gaps = 38/521 (7%) Query: 19 AMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGL 78 A + +L+ G PE NP + T +Y L + P L Sbjct: 8 ANGSGKAKDGGSLIIGVTGDPEVINPNYASDRVTL-TIQQAVYAPLFW----EVDGKPAL 62 Query: 79 AEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGG 138 A+ ++S+D TYT L+ G+ WHD K L ADDVVF+ + + + Sbjct: 63 AKSLDISDDNLTYTVKLKDGLTWHDGKP------LTADDVVFTVNSILDTKQNSPNRG-- 114 Query: 139 SYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAG 198 + +V+ VDD TV+F L F + + K + + Sbjct: 115 ------NFVFDDKPVKVEAVDDTTVKFTLPTVAPAFEN--TIKTFFPIPKHIFEGVENIE 166 Query: 199 TPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQ 258 +K + NPIG+GP++ +Y+ + + F+ Y+ KP++D + F IT D + LQ Sbjct: 167 KSDK-NKNPIGSGPYKFVEYKTGEYVSLERFNDYFDGKPKLDKVTFRITKDQNAANLALQ 225 Query: 259 KNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVN 318 E + P+D ++++ ++N++ P + Y ++N + L ++RQAL+YA++ Sbjct: 226 NGEINL-KSIQPSDRNKVEKASAVNIITYPENRLSYATFNENQPALKSKELRQALSYALD 284 Query: 319 KDAIIKAVY--QGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDL 376 ++ II A Y A + + + D V+ Y D KAK L+KE+G + + + Sbjct: 285 REEIIDAAYGSDEYAKPASSFLTENTKYFTDKVETYDQDIAKAKKLVKESGFDTSQKLTV 344 Query: 377 WAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEW---GEYLKRAKDGEHQTVMMGW 433 + + + + +A +Q + ++GV + + K+ ++ + G+ Sbjct: 345 YYL----NNSKSQESIALYLQQQYKEIGVTLDLKPTDPNALSNITLDRKNADYSIALNGY 400 Query: 434 TGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVV 493 DPD + + S A NYS + K + L + T D +R E+Y++ Q Sbjct: 401 IM-GNDPDAYKSLYLSDAP----YNYSNYHNKDLDALWEKGAVTADDKERQEIYEKIQNT 455 Query: 494 MHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVS 533 + D A I++ + G P F ++S Sbjct: 456 IADDAVIYPISYDNAVLALDSRYGGQKAATPQPVTMFRDLS 496 >4PFU-A nrPDB Length = 547 Score = 329 bits (844), Expect = 2e-90, Method: Composition-based stats. Identities = 123/524 (23%), Positives = 211/524 (40%), Gaps = 59/524 (11%) Query: 28 AKTLVYCSE--GSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVS 85 +T+ Y P +NP FT ++ +Y + + T P LAEK E Sbjct: 6 NETMYYGGSLWSPPSNWNP--FTPWNAVPGTTGLVYETMFFYDPLTGNFDPWLAEKGEWL 63 Query: 86 EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEG 145 D KTY LR+G+ WHDN L ++DV F+F+ K Y+ Sbjct: 64 -DSKTYRVVLREGIYWHDNVP------LTSEDVRFTFEIAK------------KYKGIHY 104 Query: 146 MGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDL 205 + E + ++ D+ TV FV P +L I+ K + + + + Sbjct: 105 SSVWEWLDHIETPDNRTVIFVFKDPRYHEWNELLYTL-PIVPKHIWEEKDETTILQSSNE 163 Query: 206 NPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-----PQIDTLVFSITPDASVRYAKLQKN 260 P+G+GP+ + ++ I ++ F+ +WGTK P +V +V L K Sbjct: 164 YPLGSGPYVAHSWDQNKMI-FERFENWWGTKVMGVKPAPKYVVIVRVLSNNVALGMLMKG 222 Query: 261 ECQVMPYPNPADIARMKQDKSINLMEMPGLN-----VGYLSYNVQKKPLDDVKVRQALTY 315 E + P + +K+ ++N V L N +K PL + R+A+ Sbjct: 223 ELDFSNFMLPG-VPILKKVYNLNTWYDEPPYHLSSTVVGLFLNARKYPLSLPEFRRAIAM 281 Query: 316 AVNKDAIIKAVYQGAGVSAK--NLIPPTMW--GYNDDV---QDYTYDPEKAKALLKEAGL 368 ++N D I++ VY+GA + A +P ++W Y +V + YDPE+AK++L + G Sbjct: 282 SINADPIVQRVYEGAVLKADPLGFLPNSVWMKYYPKEVVEKHGFKYDPEEAKSILDKLGF 341 Query: 369 E----KGFSIDLWAMP----VQRPYNPNARRMA-EMIQADWAKVGVQAKIVTYEWGEYLK 419 GF P ++ PY A ++I VG+ A+ + +Y + Sbjct: 342 RDVNGDGFRETPDGKPIKLTIECPYGWTDWMQAIQVIVDQLKVVGINAEPYFPDSSKYYE 401 Query: 420 RAKDGEHQTVMM-GWTGDNGDPDNFFATLFSCAASEQ----GSNYSKWCYKPFEDLIQPA 474 GE M TG + P +F T+F A E NY ++ E L++ Sbjct: 402 NMYKGEFDIEMNANGTGISSTPWTYFNTIFYPDALESEFSYTGNYGRYQNPEVESLLEEL 461 Query: 475 RAT--DDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEV 516 T D+ K EL + ++ P + + + + + V Sbjct: 462 NRTPLDNVEKVTELCGKLGEILLKDLPFIPLWYGAMAFITQDNV 505 >3T66-A nrPDB Length = 496 Score = 316 bits (809), Expect = 2e-86, Method: Composition-based stats. Identities = 106/517 (20%), Positives = 196/517 (37%), Gaps = 58/517 (11%) Query: 34 CSEGSPEGFNPQLFTSGTT-----YDASSVPLY----NRLVEFKIGTTEVIPGLAEKWEV 84 +EG+ E LF T D + +P+ LV + P LAE W+ Sbjct: 6 SNEGAGEKHIHFLFNVSTNSLDPHVDMTYIPVRAGITETLVRVDEENVTIAPWLAESWD- 64 Query: 85 SEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFE 144 S DG+ +T LR+ V + + K E++A+ V S +R + Sbjct: 65 STDGQHWTIKLREDVTFQNGK------EMDAEAVKASLERALDESVAIENALK------- 111 Query: 145 GMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLD 204 I E++ D T+ P F+++L SI+ T E Sbjct: 112 -------IDEIEA-DGYTLHITTKEPFPEFISELVNPNVSII----------DVTEEDFT 153 Query: 205 LNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQV 264 +P+GTGPF L+ + S++ +D YW ++D++ FS DAS R L+ + + Sbjct: 154 NHPVGTGPFALESFTPGSKLELVRYDEYWDGASKLDSVTFSFNEDASARSLALESGQADI 213 Query: 265 MPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIK 324 + P I ++ ++ I + L+ N+ + L DV VR+A+ +++ I+ Sbjct: 214 VYRPEVESIETLQANEGIMVEATETFRTHNLTMNLDRDSLKDVNVRRAVDVLLDRQEIVD 273 Query: 325 AVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGL--------EKGFSIDL 376 + G A PT+ + + + A L+EAG + G + Sbjct: 274 TIMLGYAEVADGPFIPTLP-FAPSYEKKETGTDIAIQYLEEAGYTLENGQMQKDGEPLHF 332 Query: 377 WAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEW-GEYLKRAKDGEHQTVMMGWTG 435 + +A++ Q++ ++G++ +I E EY+ +D + T Sbjct: 333 TVLTYGS--RAELPLIAQVFQSNAKQIGIEVEIRQIEVPEEYMASNRDWDL-ITYSNVTS 389 Query: 436 DNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMH 495 GD + + + N+S +I T D + R +L +QA + Sbjct: 390 PRGDAGYYLNATYHPTGA---LNFSSVNDPELTGIIDELNRTVDQDVRAKLTEQAAAYID 446 Query: 496 DQAPALIIAHSTVFEPV-RKEVKGYVVDPLGKHHFEN 531 +Q + H + +VK +V + N Sbjct: 447 EQKIHSFLIHPSAVVAYDENKVKNWVTTRSEYYMITN 483 >4ZE8-A nrPDB Length = 499 Score = 310 bits (795), Expect = 8e-85, Method: Composition-based stats. Identities = 120/506 (23%), Positives = 204/506 (40%), Gaps = 50/506 (9%) Query: 27 QAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKI-------GTTEVIPGLA 79 + + L G P P S +++ L+ +++P LA Sbjct: 3 ERRALRLGVNGLPNSLEPVNAISNV-GPRIVNQIFDTLIARDFFAKGAPGNAIDLVPALA 61 Query: 80 EKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSF--DRQKNAQNPYHKVSG 137 E WE D K+ F LR+ V +HD EL ADDV ++F +R + G Sbjct: 62 ESWE-RIDEKSVRFKLRQKVMFHDGV------ELTADDVAYTFSSERLWGPEAIKKIPLG 114 Query: 138 GSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKA 197 SY + E + E D TV P +A + I+ KEY + Sbjct: 115 KSYS----LDFDEPVVE----DKYTVTLRTKTPSYLIETFVASWMSRIVPKEYYKKLGAV 166 Query: 198 GTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKL 257 K P+GTGP++ ++ R+ +A D YWG KP + + I + + R A L Sbjct: 167 DFGNK----PVGTGPYKFVEFVAGDRVVLEANDAYWGPKPTASKITYQIVAEPATRVAGL 222 Query: 258 QKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 E ++ P DI + + N ++N+ ++ D K+R+AL AV Sbjct: 223 ISGEYDIITTLTPDDIQLINSYPDLETRGTLIENFHMFTFNMNQEVFKDKKLRRALALAV 282 Query: 318 NKDAIIKAVY-QGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDL 376 N+ +++A++ + A + A P ++ + Y+ E+AK L+KE+G G I Sbjct: 283 NRPIMVEALWKKQASIPAGFNFPNYGETFDPKRKAMEYNVEEAKRLVKESGY-DGTPITY 341 Query: 377 WAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGD 436 M Y NA M+ W ++GV + TY G + ++QT M W+ Sbjct: 342 HTM---GNYYANAMPALMMMIEMWKQIGVNVVMKTYAPGSF-----PPDNQTWMRNWSN- 392 Query: 437 NGDPDNFFATLFSCAASEQGSN---YSKWCYK---PFEDLIQPARATDDHNKRVELYKQA 490 + ++ E G N +W +K F +L Q + +R + Y + Sbjct: 393 ----GQWMTDAYATIVPEFGPNGQVQKRWGWKAPAEFNELCQKVTVLPNGKERFDAYNRM 448 Query: 491 QVVMHDQAPALIIAHSTVFEPVRKEV 516 + + ++APA+I+ RK+V Sbjct: 449 RDIFEEEAPAVILYQPYDVYAARKDV 474 >5KZT-A nrPDB Length = 536 Score = 300 bits (768), Expect = 1e-81, Method: Composition-based stats. Identities = 96/498 (19%), Positives = 187/498 (37%), Gaps = 36/498 (7%) Query: 55 ASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELN 114 L I G AE+ ++S+D YT LR+ KW + + Sbjct: 40 NVVNQTNEGLYALDKDGIPAIAGAAEEPKISDDKTVYTIKLREDAKWSNGDP------VT 93 Query: 115 ADDVVFSFDRQKNAQNPYHK-----VSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTR 169 A+D V+S+ R + + G PE + +K VDD T++ L++ Sbjct: 94 ANDYVYSWRRAVDPNTAATYSYLFDAIKNGGDIVAGKKKPEELG-IKAVDDYTLEVTLSK 152 Query: 170 PEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQ-KDSRIRYKA 228 P A + A L++++ + N + GPF+L+ + + + Y Sbjct: 153 PTAYINSLFAFPTFFPLNEKFVTEKGEKYAQNSD--NMLFNGPFELKDWTGTNKKWTYVK 210 Query: 229 FDGYWGT-KPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEM 287 D YW K ++ + + D+ ++ AD A ++ + + + Sbjct: 211 NDKYWDKDKVKLKQINVQVVQDSGTGLNLYNTDKVD--RTVLSADYAAQNKNNK-DYVTV 267 Query: 288 PGLNVGYLSYNVQKK----PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMW 343 + Y+ +N ++ + +R+A+ A++K + V + A NL+P Sbjct: 268 NNSSTFYIKFNQKRAGKDTVFANKNIRKAIALAIDKQSYTDTVLKNGSKPANNLVPEGFT 327 Query: 344 GYNDDVQDY--------TYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEM 395 + +DY YD ++A+ +AGL K ++ + NAR+ +E Sbjct: 328 FDPGNKEDYTKESGKHLEYDVKEAQKAW-KAGL-KELGVNEITVEFTSDDTENARKSSEF 385 Query: 396 IQADWAKV--GVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAAS 453 IQ K G+ K+ + L+ ++ ++ M GW D DP F LF + Sbjct: 386 IQDQLQKNLDGLTVKLKNVPFKVRLQNDQNQDYDFSMSGWGPDYQDPSTFL-DLFVTDGA 444 Query: 454 EQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVR 513 + +YS Y + A DD + E+ K ++++ D + + + Sbjct: 445 QNRMSYSNKDYDKILNDASVTYAADDQKRWDEMVKAEKILLTDDVAIQPLYQRSTAYLQK 504 Query: 514 KEVKGYVVDPLGKHHFEN 531 +K +P G + Sbjct: 505 DYIKNLQKNPFGPDYTYK 522 >6NPO-A nrPDB Length = 546 Score = 297 bits (759), Expect = 1e-80, Method: Composition-based stats. Identities = 95/480 (19%), Positives = 176/480 (36%), Gaps = 34/480 (7%) Query: 62 NRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFS 121 L + IP AE SEDGK YTF LRK KW + + A D VF+ Sbjct: 66 EGLYRLDKEN-KPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGD------SVTAKDFVFA 118 Query: 122 FDRQKNAQN----PYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLAD 177 + R + + + + E P VK VDD T++ L + FL Sbjct: 119 WQRLLDPKTAAEYAFIAFPIKNAEAVNKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNL 178 Query: 178 LAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP 237 +A L++++ E + GPF L ++ + + K D YW K Sbjct: 179 VAFPSYYPLNEKFVKEKGDKYGLESDTT--VYNGPFVLTDWKHEQGWKLKKNDQYWDKKT 236 Query: 238 -QIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLS 296 ++D + +S+ + + + + ++ + ++ Sbjct: 237 VKLDEINYSVVKEPATNVNLYDSGQIDF--SLLTGEFVDKYRNNKEEYGVYNEPSTFFIR 294 Query: 297 YNVQK----KPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYND--DVQ 350 N ++ PL K+R+A+ +++K + + A L+P + D D Q Sbjct: 295 LNQKRGGQDTPLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQ 354 Query: 351 DYTYD---PEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAK--VGV 405 + + P+ KA +K D + NA+++ E ++ K GV Sbjct: 355 ETFKNGVKPDAKKAAAAWEEAKKELGKDQVTIEFLNYDTGNAKKVGEYVKDQIEKNLKGV 414 Query: 406 QAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYK 465 I + + LK D ++ GW+ D DP + S+ N + + Sbjct: 415 TVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYL----DMFESKHSHNQMSFSDQ 470 Query: 466 PFEDLIQPA--RATDDHNKRVELYKQAQV-VMHDQAPALIIAHSTVFEPVRKEVKGYVVD 522 ++++I+ A D KR E +A+ ++ + + + S ++ VKG V Sbjct: 471 KYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKGVVKH 530 >4WED-A nrPDB Length = 525 Score = 295 bits (756), Expect = 3e-80, Method: Composition-based stats. Identities = 118/559 (21%), Positives = 222/559 (39%), Gaps = 63/559 (11%) Query: 3 ISLKKSGMLKLGLSLVAMTVAASV---------QAKTLVYCSEGSPEGFNPQLFTSGTTY 53 +S+K+ L+ + + +A A TL +PQ S Sbjct: 1 MSVKRRTFLQGAAGAIGLAMAQGALSKIVYAQGAAGTLRVAIAKPAGNLDPQ---SHYAI 57 Query: 54 DASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTREL 113 A ++ LV++ G ++ P LA W++ + GKT LR+GVK+ D +F Sbjct: 58 WAIQDLMFEPLVKYGKGG-QIEPCLATDWKIEDGGKTLHLTLREGVKFQDGTKFD----- 111 Query: 114 NADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAP 173 A ++ +R + F M + ++ VDD + P Sbjct: 112 -AAACKWNLERWMG------------IDQFSWMNCSKHFQSLEVVDDYHITVHFKEPVLA 158 Query: 174 FLADLAMDFAS-ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGY 232 + +L+ + LS + DA K P+GTGP+ +Q D++ ++ +DGY Sbjct: 159 LMQELSYTRPTRFLSPKSVDADGKFK-------EPVGTGPW-VQISADDTQSVFEHYDGY 210 Query: 233 WGTKPQIDTLVFSITPDASVRYAKLQKNECQVMP----YPNPADIARMKQDKSINLMEMP 288 WG KP + L + PDA R A L+ E ++ P + + + N++ P Sbjct: 211 WGDKPTYERLEAKVIPDARSRVAALRAGEIDLVGGFWIAPLTPEEGKQLEAAGFNVVVDP 270 Query: 289 GLNVGYLSYNVQK-KPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYND 347 G +++N + +PL D +VR+A++ +++ AI K +Y G A N+ + Sbjct: 271 GNVTLVMAFNPDRAEPLKDPQVRKAVSIGIDRAAISKVLYHGYAKPAGNMFSAALPYAGK 330 Query: 348 DVQDYTYDPEKAKALLKEAGL-------EKGFSIDLWAMPVQRPYNPNARRMAEMIQADW 400 D A ALL++AG + G + L + V P +R +AE+IQ++ Sbjct: 331 QFDAPVRDAAAASALLEKAGWTGSPIRSKDGKPLTL-ELVVSPDAVPGSRVIAEVIQSEM 389 Query: 401 AKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYS 460 +VG+ I + + + ++ G+ G P + F +L + S ++ Sbjct: 390 KEVGIDLVIRSVDHASKHTDMLEQKYDL---GFFLTYGAPYDPFGSLVALCLSTFKNDVE 446 Query: 461 KW--CYK-PFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVK 517 + LI A A + ++ + D + + K V+ Sbjct: 447 GKLVTDPVNLDPLINAATAATGDQIEPTI-QKVYDWLRDNDAIAPLVYVPSIWAHSKRVQ 505 Query: 518 GYVVDPLGKHH--FENVSI 534 G+ P+ ++ +EN+ + Sbjct: 506 GFT-SPVTEYDMPYENIVL 523 >3I5O-A nrPDB Length = 592 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 98/523 (18%), Positives = 189/523 (36%), Gaps = 69/523 (13%) Query: 45 QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDN 104 L+ +T+ + +Y ++ +G IP +AE++E +D KT ++R +W D Sbjct: 25 NLYAPQSTW-GTDQFMYLPAFQYDLGRDAWIPVIAERYEFVDD-KTLRIYIRPEARWSDG 82 Query: 105 KEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQ 164 + ADD V++ + K G G I VK VD V+ Sbjct: 83 VP------ITADDFVYALELTKE------------LGIGPGGGWDTYIEYVKAVDTKVVE 124 Query: 165 FVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLN-----PIGTGPFQLQQYQ 219 F + L+ + ++ ++A K +N + +GP++L Y Sbjct: 125 FKAKEENLNYFQFLSYSLGAQPMPKHVYERIRAQMNIKDWINDKPEEQVVSGPYKLYYYD 184 Query: 220 KDSRIRYKAFDGYWGTK----PQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIAR 275 + + Y+ D +WG P+ L I D ++ + P+ Sbjct: 185 PNI-VVYQRVDDWWGKDIFGLPRPKYLAHVIYKDNPSASLAFERGDIDWNGLFIPSVWEL 243 Query: 276 -MKQDKSINLMEMP-----GLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQG 329 K+ + VG++ N K L D VR+A+ YA+ + ++K Y G Sbjct: 244 WEKKGLPVGTWYKKEPYFIPDGVGFVYVNNTKPGLSDPAVRKAIAYAIPYNEMLKKAYFG 303 Query: 330 AGVSAKNLIPPTMWGYNDDVQDYT--------------YDPEKAKALLKEAGLEKG---- 371 G A + ++ DY +D + A +L EAG +KG Sbjct: 304 YGSQAHPSMVIDLFEPYKQYIDYELAKKTFGTEDGRIPFDLDMANKILDEAGYKKGPDGV 363 Query: 372 ----FSIDLWAMPVQRPYNPNAR-RMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEH 426 L + PY M EMI + +G+ K ++ + R G Sbjct: 364 RVGPDGTKLGPYTISVPYGWTDWMMMCEMIAKNLRSIGIDVKTEFPDFSVWADRMTKGTF 423 Query: 427 QTVMMGWTGDNGD-PDNFFATLFSCAASE------QGSNYSKWCYKPFEDLIQPARATDD 479 ++ G + D P N + + S+ ++ ++ +L+ A +T D Sbjct: 424 DLIISWSVGPSFDHPFNIYRFVLDKRLSKPVGEVTWAGDWERYDNDEVVELLDKAVSTLD 483 Query: 480 HNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVD 522 R + Y + Q +++ P++ ++ + + Y ++ Sbjct: 484 PEVRKQAYFRIQQIIYRDMPSIPAFYTAHWYEYSTK---YWIN 523 >4FAJ-A nrPDB Length = 564 Score = 280 bits (717), Expect = 8e-76, Method: Composition-based stats. Identities = 93/546 (17%), Positives = 205/546 (37%), Gaps = 66/546 (12%) Query: 22 VAASVQAKTLVYCSEGSP-EGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAE 80 A + + + + G+P + +P T+ + + L A Sbjct: 52 DATEKKVEQVATLTAGTPVQSLDPATAVDQTSITLLAN-VMEGLYRLDEKNQPQPAIAAG 110 Query: 81 KWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKV----S 136 + +VS +GKTYT +R G KW D ++ A D V ++ R + + V + Sbjct: 111 QPKVSNNGKTYTIVIRDGAKWSDGT------QITASDFVAAWQRVVDPKTVSPNVELFSA 164 Query: 137 GGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASIL----SKEYAD 192 + + + VK + + T++ L P F L++ + KEY Sbjct: 165 IKNAKEIASGKQAKDTLAVKSIGEKTLEIELVEPTPYFTDLLSLTAYYPVQQKAIKEYGK 224 Query: 193 -------AMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP-QIDTLVF 244 A++ G +L +GT YW K +D + F Sbjct: 225 DYGVSQKAIVTNGAFNLTNLEGVGTSDKWTIS----------KNKEYWDQKDVSMDKINF 274 Query: 245 SITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNV--QKK 302 + + + + P + A+ + K N +L N + K Sbjct: 275 QVVKEINTGINLYNDGQLD--EAPLAGEYAKQYK-KDKEYSTTLMANTMFLEMNQTGENK 331 Query: 303 PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDY------TYDP 356 L + VR+A+ YA+++++++K + V++ ++P M + +D+ ++ Sbjct: 332 LLQNKNVRKAINYAIDRESLVKKLLDNGSVASVGVVPKEMAFNPVNKKDFANEKLVEFNK 391 Query: 357 EKAKALLKEA----GLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKV--GVQAKIV 410 ++A+ +A L K S+DL + ++ E +Q G++ + Sbjct: 392 KQAEEYWDKAKKEIDLSKNTSLDLLVSDGEF-----EKKAGEFLQGQLQDSLEGLKVTVT 446 Query: 411 TYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDL 470 +++R + + GW D DP +F A + + G + K +++L Sbjct: 447 PIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMNHGG----YSNKNYDEL 502 Query: 471 IQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLG-KHHF 529 ++ + + KR + K+A+ ++ + + I + + ++K ++ +G K+ + Sbjct: 503 LKDSSS-----KRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKIKNVLMHSIGAKYDY 557 Query: 530 ENVSIE 535 + + IE Sbjct: 558 KKMRIE 563 >5ZA4-A nrPDB Length = 488 Score = 278 bits (710), Expect = 5e-75, Method: Composition-based stats. Identities = 122/525 (23%), Positives = 212/525 (40%), Gaps = 59/525 (11%) Query: 25 SVQAKTLVYCSEGSP--EGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKW 82 S + + + P GF+P L +SG + A+++ ++ LV+ T + LA K Sbjct: 3 SSPSGSTIEAGIAYPISTGFDP-LTSSGASSMAANLHIFEGLVDLHPVTRQPYLALAAKE 61 Query: 83 EVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEY 142 +D TY LR+G +HD + +DVV+SF+R + + Sbjct: 62 PEQKDDLTYYISLREGAMFHDGSP------VTTEDVVYSFERVLDPAKASLFAQFIPF-- 113 Query: 143 FEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEK 202 I+ V +DDN V+F L P A F L + I+ K +A A Sbjct: 114 ---------IASVTALDDNVVEFKLKYPFALFKERLTI--IKIVPKHIVEAGQSA----- 157 Query: 203 LDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP-QIDTLVFSITPDASVRYAKLQKNE 261 D PIG+GP++ KD RI ++A Y G P +++ + + + D + R + Sbjct: 158 FDAKPIGSGPYKFVSATKDDRIVFEANTVYNGHYPAKVEKMTWFLLSDDAARVTAQESGR 217 Query: 262 CQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDA 321 Q + D R+K+ ++ ++ GL +L +N +K P D+ KVRQAL YA++K Sbjct: 218 VQAIESVPYLDAERLKRKNNVESVQSFGL--LFLMFNCEKAPFDNPKVRQALHYALDKQK 275 Query: 322 IIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPV 381 +I V+ G +A + + T Y Y YD KA+ LL EAG+ + Sbjct: 276 LIDIVFLGNAKAATSYLQDTHPDYVKASSQYDYDKAKAEKLLAEAGITN------LTFQL 329 Query: 382 QRPYNPNARRMAEMIQADWAKVG-VQAKIVTYEWGEYLKRAKD-GEHQTVMMGWTGDNGD 439 + + A +I W + V+ + + G D G ++ V+ GD Sbjct: 330 LATDHAWVKECAPLILESWNALSVVKVTLQHLQSGALYSAHVDKGAYEVVIA-----PGD 384 Query: 440 PDNFFATL-----------FSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYK 488 P F L + +N +++ + L+ A + ++ Sbjct: 385 PSVFGNDLDLLLSWWYRGDVWPKRRFRWANTAEYH--EVQKLLDEAIK--NPAGSKVAWQ 440 Query: 489 QAQVVMHDQAPALIIAHSTVFEPVR-KEVKGYVVDPLGKHHFENV 532 +A ++ +Q P I H + K++ + P F V Sbjct: 441 KAINIIAEQVPLYPIIHRKLPTAWNTKKLTDFQPLPTTGLSFLGV 485 >1ZTY-A nrPDB Length = 529 Score = 278 bits (710), Expect = 5e-75, Method: Composition-based stats. Identities = 112/514 (21%), Positives = 209/514 (40%), Gaps = 64/514 (12%) Query: 41 GFNPQLFTSGTTYDASSVPLYNRLVEFK--IGTTEVIPGLAEKWEVSEDGKTYTFHLRKG 98 FNP L T+ T ++ +Y LV F G T V LAE +++++D + TF +RKG Sbjct: 17 NFNPYLATNLRT---TTDFIYEPLVVFNEMKGNTPVF-RLAESYKMADDLMSVTFDIRKG 72 Query: 99 VKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKV 158 VKW D + F ADDVV+SF K + G+ + ++ V+KV Sbjct: 73 VKWSDGEAF------TADDVVYSFGLLKAKPE------------LDQRGINKWVTSVEKV 114 Query: 159 DDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQ- 217 D+ V+F L+ + ++++ I+++ + T + NP+GTGPF + Sbjct: 115 DEYKVRFRLSEANSNVPYEISL--IPIVAEHVWKDVKDPTTF--TNENPVGTGPFTVIDT 170 Query: 218 YQKDSRIRYKAFDGYWGTKP-QIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM 276 + I+ YW ++D L + K+ +E P DI R Sbjct: 171 FTPQLYIQC-RNPNYWDAANLEVDCLRVPQIANNDQLLGKIVNSELDWTSSFVP-DIDRT 228 Query: 277 KQDKSIN---LMEMPGLNVGYLSYNV----QKKPLDDVKVRQALTYAVNKDAIIKAVYQG 329 + N G +++ +K+ LD+V R+A + A+++ II + G Sbjct: 229 YAAANPNHHYWYPAAGTQAFMVNFKNPDPAKKEALDNVDFRRAFSMALDRQTIIDIAFYG 288 Query: 330 AGVS---AKNL-IPPTMWGYNDDVQDYT----YDPEKAKALLKEAGLE----KGF----S 373 +G A L W + Y YD E +K LL +AG + GF S Sbjct: 289 SGTVNDFASGLGYAFEAWSDEATHKKYKGFNTYDVEGSKKLLAKAGFKDVNGDGFVETPS 348 Query: 374 IDLWAMPVQRPYNPNA-RRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMG 432 + + +Q P ++ +VG++AK T E+ Y + +G + Sbjct: 349 GKSFELLIQSPNGWTDFNNTVQLAVEQLQEVGIKAKARTPEFAVYNQAMLEGTYDVAYTN 408 Query: 433 WTGDNGDPDNFFATLFSCAASEQGSNYSKWC-----YKPFEDLIQPARATDDHNKRVELY 487 + DP ++ + + +A + G ++ K + L+ T D N+++ + Sbjct: 409 YF-HGADPFTYWNSGY-NSALQSGDGMPRFAMHYFTDKKLDGLLDSFYKTADKNEQLAIA 466 Query: 488 KQAQVVMHDQAPALII-AHSTVFEPVRKEVKGYV 520 Q ++ + + + + + +++ G+ Sbjct: 467 HGIQKIIAENQVTIPVMSGAWMYQYNTTRFTGWW 500 >5YQW-A nrPDB Length = 532 Score = 277 bits (708), Expect = 9e-75, Method: Composition-based stats. Identities = 103/514 (20%), Positives = 197/514 (38%), Gaps = 63/514 (12%) Query: 41 GFNPQLFTSGTTYDASSVPLYNRLVEFK--IGTTEVIPGLAEKWEVSEDGKTYTFHLRKG 98 FNP L T ++ +Y LV F G T V LAE +++S+D + TF +RKG Sbjct: 19 NFNPFLG--ATNLHTTTDFIYEPLVVFNEMHGNTPVF-RLAENFQMSDDLMSVTFDIRKG 75 Query: 99 VKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKV 158 VKW D + F ADDVV+SF+ K + G+ ++ V+KV Sbjct: 76 VKWSDGEAF------TADDVVYSFNLVKEKPE------------LDQSGINSWVTGVEKV 117 Query: 159 DDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQ- 217 +D V+F L+ + ++A ++ K + T + NP+G+GPF + Sbjct: 118 NDYQVKFRLSEANSNVPYEIAK--VPVVPKHVWSKVKDPSTF--TNENPVGSGPFTVIDT 173 Query: 218 YQKDSRIRYKAFDGYWGTKP-QIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM 276 + I+ + YW +D L + K+ E P Sbjct: 174 FTPQLYIQCE-NPNYWDAANLDVDCLRVPQIANNDQFLGKVVNGEMDWTSSFVPDIDRTY 232 Query: 277 KQDKSINLMEMPGLNVGYLSYN------VQKKPLDDVKVRQALTYAVNKDAIIKAVYQGA 330 + P N + + L +V R+A + A+++ II + G Sbjct: 233 AAASPKHHYWYPPAGTQAFVVNFKNPDAAKNEALTNVDFRRAFSMALDRQTIIDIAFYGG 292 Query: 331 GVSAKNLIPPTMWGYN--------DDVQDY-TYDPEKAKALLKEAGL----EKGF----S 373 G + + + D + Y +Y+ E AK LL +AG + GF S Sbjct: 293 GTV-NDFASGLGYAFEAWSDEKTHDKFKAYNSYNAEGAKKLLAKAGFKDVNKDGFVDTPS 351 Query: 374 IDLWAMPVQRPYNPNA-RRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMG 432 + + +Q P ++ A+VG++A+ T ++ Y + +G + Sbjct: 352 GKSFELLIQSPNGWTDFNNTVQLAVEQLAEVGIKARARTPDFSVYNQAMLEGTYDVAYTN 411 Query: 433 WTGDNGDPDNFFATLFSCAASEQGSNYSK-----WCYKPFEDLIQPARATDDHNKRVELY 487 + DP ++ + + +A + G + + + + L+ T D +++E+ Sbjct: 412 YF-HGADPYTYWNSAY-NSALQSGDGMPRFAMHFYKNEKLDGLLNSFYKTADKQEQLEIA 469 Query: 488 KQAQVVMHDQAPALI-IAHSTVFEPVRKEVKGYV 520 Q ++ + ++ + +++ G+ Sbjct: 470 HGIQQIIAQDQVTIPVLSGAYMYQYNTTRFTGWW 503 >2WOP-A nrPDB Length = 562 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 107/563 (19%), Positives = 203/563 (36%), Gaps = 68/563 (12%) Query: 16 SLVAMTVAASVQAKTLVYCSEGSPEGFNP---QLFTSGTTYDASSVPLYNRLVEFKIGTT 72 + A+ + + TL S + +P + L + Sbjct: 20 GVGALVNPSRRRGGTLRLVSSADVDSLDPARTYYVWVWLLQRLLNRTLMAYPTDPGPAGL 79 Query: 73 EVIPGLAE-KWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQK----- 126 P LAE EVS+ G+T+T+ LR+G+++ D + +DDV + R Sbjct: 80 VPAPDLAEGPGEVSDGGRTWTYRLRRGLRYDDGTP------ITSDDVRHAVQRVFAQDVL 133 Query: 127 --NAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFAS 184 + Y E + V D++T+ F LTRP + F +A A+ Sbjct: 134 PGGPTYLIPLLDDPERPYPGPYRTDEPLRSVLTPDEHTIVFRLTRPFSDFDHLMAQPCAA 193 Query: 185 ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWG-----TKPQI 239 + + ++ T +P +GP+++ +++ D+ + + +W +P + Sbjct: 194 PVPR-------RSDTGADYGRDPRSSGPYRVARHEPDTLLHLERNP-HWDRATDPIRPAL 245 Query: 240 -DTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLN-----VG 293 D + +I D V A+L E + A ++ + ++ N + Sbjct: 246 PDRVELTIGLDVDVLDARLIAGEFDINLEGRGLQHAAQRRATADEVLRSHTDNPRTSFLH 305 Query: 294 YLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNL----IPPTMWGYN--- 346 +++ P D+V VR+A+ YA +K I+ +G V+ +L PPT+ + Sbjct: 306 FVAMQPHIPPFDNVHVRRAVQYAADK--ILLQDARGGPVNGGDLTTALFPPTLPAHQDLD 363 Query: 347 --DDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVG 404 D D + A+A L AGL GF + R +A+ + A+VG Sbjct: 364 LYPTGPDLRGDLDAARAELAAAGLPDGFRAVIGTQ------RGKFRLVADAVVESLARVG 417 Query: 405 VQAKIVTYEWGEYL-------KRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGS 457 ++ + + Y + ++ ++ W D F A L + Sbjct: 418 IELTVKELDVATYFSLGAGHPETVREHGLGLLVTDWGADFPTEYGFLAPLV--DGRQIKR 475 Query: 458 NYSKWCYKPFED-----LIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPV 512 N W +D LI T D R EL++ + + + A L + H Sbjct: 476 NGGNWNLPELDDPEVNALIDETLHTTDPAARAELWRAVERRVMEHAVLLPLVHDKTLHFR 535 Query: 513 RKEVKGYVVDP-LGKHHFENVSI 534 V V P G + + + + Sbjct: 536 NPWVTNVYVHPAFGLYDIQAMGL 558 >4XKN-A nrPDB Length = 473 Score = 270 bits (690), Expect = 1e-72, Method: Composition-based stats. Identities = 81/464 (17%), Positives = 170/464 (36%), Gaps = 39/464 (8%) Query: 62 NRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFS 121 L + ++ L + + + T L+ +K+ + + +L A+ V S Sbjct: 37 ESLFKTN-DQGKIEKALVKSY-HQPNDTTLDIELKDNIKFQNGQ------KLTAEKVKSS 88 Query: 122 FDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMD 181 + + S +G + +++LA Sbjct: 89 LENSMKKSDLVKYSLPISSITAKGQK---------------LTIKTNSAYPELVSELANP 133 Query: 182 FASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDT 241 F +I ++ P+GTGP+Q++ Y++ +I F YW KP++D Sbjct: 134 FMAIYD---------TDAKSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDH 184 Query: 242 LVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQK 301 + + D + R L+ + ++ + ++ ++++ + + G L YN Sbjct: 185 ITVTYQEDGNNRVRNLESQKDDLITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTN 244 Query: 302 KPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKA 361 K + VR+AL + +++ I +YQG A + + + + + E+AK Sbjct: 245 KKMT-KSVREALDHIIDRQGIADHIYQGYAKPATSPFNDKIPYI-KEPKLTKQNIEQAKM 302 Query: 362 LLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRA 421 LL + G K + + + P ++A+++Q+D K ++ I + + E + Sbjct: 303 LLAKDGYTKEHPLKIKL--ITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGYLKD 360 Query: 422 KDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHN 481 + T+ T GD FF + + + + +DLI T D Sbjct: 361 RSAWDATMYSFGTIPRGDTGYFFNQAYKKDGAINKGD---YNNSNVDDLINQLNHTVDVK 417 Query: 482 KRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLG 525 +R + + P IA++ +VK Y V P G Sbjct: 418 ERHNISNDIIKLSSRDVPNSYIAYNDQIVAANSKVKNYKVTPEG 461 >4OFL-A nrPDB Length = 499 Score = 243 bits (621), Expect = 1e-64, Method: Composition-based stats. Identities = 98/468 (20%), Positives = 174/468 (37%), Gaps = 64/468 (13%) Query: 28 AKTLVYCSEGSP-EGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSE 86 TL P EGF+P L S +Y PL + +F + L +++ S+ Sbjct: 2 THTLQLAIGDEPTEGFDPMLGWSHGSYLLLHSPLLKQNEDFSWDSL-----LLSQYQPSD 56 Query: 87 DGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGM 146 DGKT+ L+ +K+ D L A DV F+++ NA KV G++ Sbjct: 57 DGKTWLLTLKPDLKFSDGSP------LTAKDVAFTYN---NAAASGGKVDMGNF------ 101 Query: 147 GLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLN 206 + +D V+ L P++ F+ L I+S + +A A Sbjct: 102 ------LSAEVIDPLNVRIHLKAPQSTFVNVLGS--LGIVSADKYNAKTYA-------QK 146 Query: 207 PIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMP 266 PIG GP++L +Q ++ +A Y G K D L+F + D +A Q + V+ Sbjct: 147 PIGAGPYRLVSFQPGQQMIVEANPYYAGNKNDFDKLIF-VFLDEDSAFAAAQSGQLGVVR 205 Query: 267 YPNPADIARMKQ----------DKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYA 316 P + + ++ I P Y + DV +R+A+ YA Sbjct: 206 IPPSMAVGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTADVAIRRAINYA 265 Query: 317 VNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGL-------- 368 +N+ + + +G + A + W N D D +KAK +L++AG Sbjct: 266 INRQLLADQIMEGHAIPAYTGVQGLPW-NNPDSAIKDGDIDKAKQILEQAGWQLNSQGTR 324 Query: 369 -EKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQ 427 + G + + R +A+ +++ +G+ + + W + Sbjct: 325 EKNGLPAKITLWYTS--GDTTRRDLAQALRSMLKPIGIDVDLKSGSWETVERNMHA---N 379 Query: 428 TVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPAR 475 + GW DP + S AA + N + + +Q A Sbjct: 380 PTLFGWGS--LDPMELYHHYSSNAAGVEYYNPGYYKNPMVDKHLQQAL 425 >4ONY-A nrPDB Length = 595 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 94/569 (16%), Positives = 193/569 (33%), Gaps = 94/569 (16%) Query: 29 KTLVYCSEGSPEGFNPQ-----------LFTSGTTYDASSVPLYNRLVEFKIGTTEVIPG 77 +L G+ + NP L+ G + L ++ + + Sbjct: 45 GSLTVGVVGTFDSLNPFVLKSMRTTARGLYNDGEFGNMVYQTL---MLRSRDEPFTLYSL 101 Query: 78 LAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSG 137 LAEK + + K F L KW D + + DDV+F++D P + Sbjct: 102 LAEKVAIDPERKWVEFTLNPKAKWSDGQP------VTVDDVLFTYDILTEKGRPPYNSRM 155 Query: 138 GSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKA 197 +++++K + +V+F L +L K A+ + Sbjct: 156 ------------SRVAKIEKTGERSVRFTFNEKSDREFPMLIAGSMPVLPKH---AINRD 200 Query: 198 GTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTK-------PQIDTLVFSITPDA 250 PIG+GP+ + Q RI YK YWG D + + Sbjct: 201 TFGNSTLEPPIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNE 260 Query: 251 SVRYAKLQKNECQVMPYPNPADIARMKQDKSINL---------MEMPGLNVGYLSYNVQK 301 + + +K + NP ++ ++ P +G++ +N ++ Sbjct: 261 TSLFESFKKGILDIFIEGNPIRWEKLYDFPAVEQGKVIKDTFEKGTPADMLGFV-FNTRR 319 Query: 302 KPLDDVKVRQALTYAVN--------------------KDAIIKAVYQGAGVSAKNLIPPT 341 D +VRQAL + + + + +V + A + L+ P Sbjct: 320 PIFADRRVRQALGLLFDFEWANSNLFAGQYRRTQSFWEGSQLSSVGRPADARERELLAPF 379 Query: 342 MWGYNDDVQDYTYDP-------------EKAKALLKEAG--LEKGFSIDLWAMPVQRPY- 385 +DV + T+ P +KA LL +AG + G +ID A P Sbjct: 380 PGAVREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAIDPTAKPFAFEIM 439 Query: 386 --NPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDN- 442 +P+ ++A Q + +++G+ +I T + +Y +R + ++ ++ G + P N Sbjct: 440 TRSPDEEKIALAYQRNLSRLGIAVEIHTVDDAQYQQRLQTFDYDMIL-GALASSLSPGNE 498 Query: 443 -FFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPAL 501 + + + N++ + +I+ A + V + V+ + Sbjct: 499 QWLRWGSASRDVQGSFNFAGVADPAVDAMIEALLAARNRADFVSAVRALDRVLISGDYYV 558 Query: 502 IIAH-STVFEPVRKEVKGYVVDPLGKHHF 529 + H + ++ PL + Sbjct: 559 PLYHLPYQWVARWDRIEHPQKTPLSGYQL 587 >3DRH-A nrPDB Length = 590 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 106/505 (20%), Positives = 185/505 (36%), Gaps = 69/505 (13%) Query: 67 FKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQK 126 F + I G A + ++ KT T LRK +KW D E+ A D F+++ Sbjct: 74 FTDSGFKFIKGGAADVALDKESKTATITLRKDLKWSDG------SEVTAKDYEFTYETIA 127 Query: 127 NAQNPYHKVSGGSYEYFEGM----GLPELISEVKKVDDN-----TVQFVLTRP------E 171 N + + G + IS + D VQF +P Sbjct: 128 NPAYGSDRWTDSLANIVGLSDYHTGKAKTISGITFPDGENGKVIKVQFKEMKPGMTQSGN 187 Query: 172 APFLADLA--MDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAF 229 FL +A + K+ A + K P+ TGPF+ + I+Y Sbjct: 188 GYFLETVAPYQYLKDVAPKDLASS-------PKTTTKPLVTGPFKPENVVAGESIKYVPN 240 Query: 230 DGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPG 289 YWG KP+++++ + + A A L ++ ++ + ++K K ++ Sbjct: 241 PYYWGEKPKLNSITYEVVSTAKS-VAALSSSKYDIINGMVSSQYKQVKNLKGYKVLGQQA 299 Query: 290 LNVGYLSYNV-------------QKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKN 336 + + + YN+ +K PL D VRQA+ YA N + G A + Sbjct: 300 MYISLMYYNLGHYDAKNSINVQDRKTPLQDQNVRQAIGYARNVAEVDNKFSNGLSTPANS 359 Query: 337 LIPPTMWGYN-DDVQDYT-YDPEKAKALLKEAGLEKGFSI--------DLWAMPVQRPYN 386 LIPP + V+ Y D +KA LL E G + S +L + R + Sbjct: 360 LIPPIFKQFTSSSVKGYEKQDLDKANKLLDEDGWKLNKSTGYREKDGKELSLVYAARVGD 419 Query: 387 PNARRMAEMIQADWAKVGVQAKIVT---YEWGEYLKRAKDG----EHQTVMMGWTGDNGD 439 NA +A+ W K+GV+ + E+ ++ + W+ + + Sbjct: 420 ANAETIAQNYIQQWKKIGVKVSLYNGKLMEFNSWVDHMTTPPGANDWDITDGSWSLAS-E 478 Query: 440 PDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQ--PARATDDHNKRVELYKQAQVVMHDQ 497 P LFS AA N+ + + + +++ R + + Q M+ + Sbjct: 479 PSQ--QDLFSAAAP---YNFGHFNDSEITKDLNDIDSAKSENPTYRKAAFVKYQEDMNKK 533 Query: 498 APALIIAHSTVFEPVRKEVKGYVVD 522 A + + PV K V G +D Sbjct: 534 AYVIPTNFMLNYTPVNKRVVGMTLD 558 >2D5W-A nrPDB Length = 603 Score = 225 bits (573), Expect = 4e-59, Method: Composition-based stats. Identities = 102/586 (17%), Positives = 188/586 (32%), Gaps = 113/586 (19%) Query: 25 SVQAKTLVYCSEGSPEGF--NPQLFTSGTTYDASSVP-LYNRLVEFKIGTTEVIPGLAEK 81 Q +LV + P + S + L+ + F + P LA + Sbjct: 2 GPQDNSLVIGASQEPRVLAGDFLRVISNQAIKSEIEQYLFAPFIGFNADSQNF-PVLATE 60 Query: 82 WEVSEDGK-------------TYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNA 128 E+G+ +R KW D R + +DV F F+ K Sbjct: 61 VPTLENGRLRVTDIGGGKKRLEMDITIRPDAKWSDG------RPITTEDVAFYFEVGKAK 114 Query: 129 QNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSK 188 P E + V+ D + P + + K Sbjct: 115 GMP-----------VLNPDFWERV-NVRIKDARNFTLIF-EPAYYYDTYG--PINTYAPK 159 Query: 189 EYADAMMKAGTPEKLDLNP-----------------------------IGTGPFQLQQYQ 219 + L+P + +GPF+L+++ Sbjct: 160 HIMGPEWERVKAAARGLDPDKDAEKLNELYRNFFLKFATPQALNRGAMVYSGPFKLKRWV 219 Query: 220 KDSRIRYKAFDGY-----WGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPY------- 267 + I + + G + +V+ + + + Sbjct: 220 PGNSIEMERNPNFPIKPEGGESKYVQKVVYRFIQNTNSLLVAVIGGSIDATSSVSLTFDQ 279 Query: 268 PNPADIARMKQDKSINLMEMPGLNVGYLSYN-------VQKKPLDDVKVRQALTYAVNKD 320 + R + ++ +PG ++ N V+ L+D + RQA+ +A+N++ Sbjct: 280 GRSPQLVR-RAPGRFDIWFVPGAIWEHIDINKFENCQVVKDLGLNDKRTRQAILHALNRE 338 Query: 321 AIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEK---------- 370 ++KA + G A I P +N +V+ Y +D +KA+ALL E G K Sbjct: 339 GLVKAFFDGLQPVAHTWIAPVNPLFNPNVKKYEFDLKKAEALLAEMGWRKGPDGILQRTV 398 Query: 371 -GFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWG-----EYLKRAKDG 424 G ++ V N R + D K+G+ KI E+++RA + Sbjct: 399 NGRTVRFEIEYVTTAGNVVRERTQQFFAEDLKKIGIAVKINNAPSAVVFADEFIQRASEC 458 Query: 425 EHQTVM-MGWTGDNGDPDNFF--------ATLFSCAASE-QGSNYSKWCYKPFEDLIQPA 474 + + W + + + F A + + QG N W F+ L A Sbjct: 459 KWTGMFEFAWVSNLQEDGSLFQYKNLNTGAIMVPTKENNYQGQNIGGWRNDEFDRLTSQA 518 Query: 475 RATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV 520 D +R +L+ +AQ + ++ PAL + VRK + YV Sbjct: 519 VLEFDPERRKQLFWRAQEIWAEELPALPLYFRANPYVVRKGLVNYV 564 >6EQ0-A nrPDB Length = 683 Score = 213 bits (543), Expect = 1e-55, Method: Composition-based stats. Identities = 107/569 (18%), Positives = 185/569 (32%), Gaps = 83/569 (14%) Query: 20 MTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYN------RLVEFKIGTTE 73 M V T+ + G PEG+N + + + L L + TE Sbjct: 78 MPDGVGVYGDTMRHVVGGRPEGWN-YIAGQSQGWGGIDIALSECLTRTAPLFQVDAKDTE 136 Query: 74 VIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYH 133 +P LA+ WE SEDG T T HL KG KW D + F NADDV+F ++ N Sbjct: 137 PLPNLAKSWEWSEDGHTLTMHLVKGAKWSDGEAF------NADDVMFYWEDAVVDPNVSP 190 Query: 134 KVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEA-PFLADLAMDFASILSKEYAD 192 G S E F + +KK+DD TV++ +L +A Sbjct: 191 LGGGASPEAFGEG------TTLKKIDDYTVEWTFKAAFPKQYLYTMAYPSFCPGPSHILK 244 Query: 193 AMMKAGTPEKLDL----------NPIGTGPFQLQQYQKDSRIRYKAFDGYW--GTK---- 236 + + N G + Y+ D I + YW K Sbjct: 245 PQHPKYSKNTYNQFKNAFPPEYMNMPVMGAWVPVSYRPDDLIVLRRNPYYWKVDEKGQQL 304 Query: 237 PQIDTLVFSITPDASVRYAKLQKNECQVMPYPNP-ADIARMKQDKSINLMEMPGLNVGYL 295 P ++ + + ++ A + P +A +K+ N + Sbjct: 305 PYLNEVHYKLSTWADRDVQAV-AGSGDFSNLEQPENFVASLKRAADPNAPARLAFGPRLI 363 Query: 296 SYNVQ------------------KKPLDDVKVRQALTYAVNKDAIIKAVYQG--AGVSAK 335 YN+Q ++ + RQA+T A+++ AI ++ +G + Sbjct: 364 GYNLQMNFSANGWGNPDERGQAIRELNRNEVFRQAVTSALDRKAIGDSLVKGPFTAIYPG 423 Query: 336 NLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQ------------- 382 + T + Y ++ E AKA L GL+ P + Sbjct: 424 GISSGTSFYDRASTVYYPFNLEGAKAALASIGLKDTDGDGFLNFPKETLGGRNVEITLLV 483 Query: 383 RPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQ-TVMMGWTGDNGDPD 441 + +AE + AK+G++ I + + + G+ V T + Sbjct: 484 NNGYATDKSLAEGLVGQMAKLGLRVVIHSLDSNQRDAAHYGGQFDWLVRRNSTELSSVVQ 543 Query: 442 NFFATLFSCAASEQGSNYSKWCYKPFE---------DLIQPARATDDHNKRVELYKQAQV 492 N + N+ K + D+++ ++ D+ +R +L KQ Q Sbjct: 544 N--TEQLAPVGPRTSWNHRSPEGKELDLMPFEKEMADIVRKFISSQDNAERADLMKQYQK 601 Query: 493 VMHDQAPALIIAHSTVFEPVRKEVKGYVV 521 V + + V K Sbjct: 602 VYTQNLYTIGLTEYPGALIVNKRFSNVPQ 630 >5IPW-A nrPDB Length = 633 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 91/467 (19%), Positives = 163/467 (34%), Gaps = 76/467 (16%) Query: 55 ASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELN 114 S + +L + +++PGLA+ WEV E+G+ Y FHLRKGVKW D + Sbjct: 75 GISKLIEVKLAFWDKEGGKLVPGLAKSWEVLENGRVYIFHLRKGVKWSDGAPY------T 128 Query: 115 ADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPF 174 A D+VF + + + +V+ +DD TV+F ++P F Sbjct: 129 AHDIVFWVNDIVGNDDITPSKP----------DWYNIGVKVEALDDYTVKFEFSKPYGLF 178 Query: 175 LADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTG----------------------- 211 L + + Y TP + + G Sbjct: 179 LLKVPYGGFTGAPAHYLKQFHPKYTPMEEIEKKMVEGVHNTWVDLFNDKNDFLENTELPT 238 Query: 212 --PFQLQQYQKDSRIRYKAFDGYW------GTKPQIDTLVFSITPDASVRYAKLQKNECQ 263 P++ + + +W P ID + + V K E Sbjct: 239 LSPWKPITDPTEQFYILERNPYFWAVDIEGNQLPYIDYVRHEYVKNDEVILLKAISGEID 298 Query: 264 V---------MPYPNPADIARMKQDKSINL--MEMPGLNVGYLSYN------VQKKPLDD 306 + N + Q + + +S N V +K +D Sbjct: 299 MQWRHIGGLGAGAGNFTLLMENSQSGGYRVLKWIAANGSASRISLNYAHSDEVLRKVFND 358 Query: 307 VKVRQALTYAVNKDAIIKAVYQGAGVS-AKNLIPPTMWGYNDDVQDY-TYDPEKAKALLK 364 V+ RQAL+ A+N++ I + ++ G +L+ + + + + Y YDP++A LL Sbjct: 359 VRFRQALSLAINREEINEILFNGLAEPRQASLVSGSPYFDPEWEKAYAEYDPDRANKLLD 418 Query: 365 EAGLEKGFSIDLWAMPVQRPYNPNARRMAEM-------IQADWAKVGVQAKIVTYEWGEY 417 E GL+ + +P RP + ++ W ++GV +I E + Sbjct: 419 EMGLKWDDKHEYRLLPDGRPLRFTITVTGQFHVDVWTMVKEYWKQIGVWVEIENLERSLF 478 Query: 418 LKRAKDGEHQTVMMGWTGDN-GDPDNFFATLFSCAASEQGSNYSKWC 463 +RA G+ ++ W D P + +F + + Y W Sbjct: 479 YERADAGDFDAMV--WNMDRAAQPLSSPMVIFPGSENIADFWYIGWS 523 >5ICQ-A nrPDB Length = 610 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 80/542 (14%), Positives = 174/542 (32%), Gaps = 78/542 (14%) Query: 21 TVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLV-EFKIGTTEVIPGLA 79 A+ + L G+ + NP SGT ++ L+ + + P +A Sbjct: 56 ADPAAKKGGRLRVGLPGTFDSLNPFNVKSGTAAQGLVGNVFQGLMARSQDEPFTLYPLIA 115 Query: 80 EKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGS 139 + ++ TFHL + D K + A+DV+FSFD K P +++ G Sbjct: 116 QSIDIDPARTRVTFHLDPRAHFSDGKP------ITAEDVLFSFDLLKAKGRPQQRIAYGL 169 Query: 140 YEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGT 199 + + ++ V D + +L +L K A+ Sbjct: 170 VKSATAPDPHRVAYDLTGVGDRELPLILA-------------IMPVLPKH---ALDVERF 213 Query: 200 PEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKP-------QIDTLVFSITPDASV 252 + P+G+GP+ + Q +R+ K YWG D + D + Sbjct: 214 SDATLAKPLGSGPYVVADVQAGARLLLKRDPNYWGADIPSQRGFYNFDEIDLQYFRDGNS 273 Query: 253 RYAKLQKNECQVMPYPNPADIARMKQDKSI--------NLMEMPGLNVGYLSYNVQKKPL 304 + + + + ++ +L + +N ++ Sbjct: 274 LFEAFKAGLIDYRDETSTTRWSTGYDFPALRDGRMARESLKNENPKGLNGFVFNTRRALF 333 Query: 305 DDVKVRQALTYAVNKDAIIKAVY--------------------QGAGVSAKNLIPPTMWG 344 D ++R+A + + + Y +GA + L+ P Sbjct: 334 KDARLREAFGMMFDFEWVNANYYAGLYTRTKSFFDESELSSSGRGASEKERALLAPWPDA 393 Query: 345 YNDDVQDYTY----------DPEKAKA---LLKEAGLE-KGFSIDLWAMPVQRPY---NP 387 ++ + + D + A+ LL AG G + P + Sbjct: 394 VRAEILEGEWRPPVSDGSGRDRDMARRALDLLAAAGCRVDGDRLMKDGEPFSFEIMVKDR 453 Query: 388 NARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATL 447 + R+A + A++GV+ ++ + +Y +R + + ++ + + P N Sbjct: 454 DQERLALAYASSLARIGVEVRVRLVDEVQYQRRRQKFDFDMMIGQYVA-SASPGNEQRMR 512 Query: 448 FSCAAS--EQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAH 505 +S A + E N + + +I + V + V+ + + H Sbjct: 513 WSSATANQESSFNLAGAASPAIDGMISALLSARSQEDFVTAVRAYDRVLLSGFYVVPLFH 572 Query: 506 ST 507 ++ Sbjct: 573 AS 574 >2GRV-A nrPDB Length = 621 Score = 111 bits (278), Expect = 7e-25, Method: Composition-based stats. Identities = 75/473 (15%), Positives = 144/473 (30%), Gaps = 75/473 (15%) Query: 30 TLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPG---------LAE 80 ++ + GFNP L + + +A+ L F+ P L E Sbjct: 49 QIIMAIDSIGPGFNPHLLSDQSPVNAAIASLVLP-SSFRPVPDPTSPTGSRWELDTTLLE 107 Query: 81 KWEVS-EDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGS 139 EV+ E+ T T+ +R +W DN + ADD + + + + V Sbjct: 108 SAEVTQENPFTVTYKIRPEAQWTDNAP------IAADDYWYLWRQMVSQP---GVVDPAG 158 Query: 140 YEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGT 199 Y+ G + V+ ++P + F IL + Sbjct: 159 YDLITG------VQSVE--GGKQAVVTFSQPYPAWREL----FNDILPAHIVKDIPGGFG 206 Query: 200 PEKLDLNPIGTGPFQLQQYQKD-SRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQ 258 P+ G F+++ I D +W + D ++F + ++ Sbjct: 207 AGLARAMPVTGGQFRVETIDPQRDEILLARNDRFWSVPAKPDLVLFRRGGAPAALADSIR 266 Query: 259 KNECQVMP-YPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAV 317 + QV + A A++ + + V L+ Q+ L D +VR+A+ + Sbjct: 267 NGDTQVAQVHGGAATFAQLSAIPDVRTARIVTPRVMQLTLRAQQPKLADPQVRKAILGLI 326 Query: 318 NKDAII-------KAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGL-- 368 + D + V P + + + A LL++AG Sbjct: 327 DVDLLASVGAGDDNTVTLAQAQVRSPSDPGYVPTAPPAMTR-----DDALELLRDAGYVS 381 Query: 369 -----------------------EKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGV 405 + G + + +P + +A VG+ Sbjct: 382 EPVPPPDNTADDPPPDNGRERIVKDGVPLTIVL--GVASNDPTSVAVANTAADQLRNVGI 439 Query: 406 QAKIVTYE-WGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGS 457 A ++ + Y + V+ GW GD A+ + C A E Sbjct: 440 DASVLALDPVALYGDALVNNRVDAVV-GWRQAGGDLATVLASRYGCRALEATP 491 >4YRY-B nrPDB Length = 468 Score = 34.8 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 40/129 (31%), Gaps = 9/129 (6%) Query: 359 AKALLKEAGLE----KGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEW 414 A A L + G + F + P +R+ E + K+GV + T Sbjct: 155 AAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVG 214 Query: 415 GEYLKRAKDGEHQTVMMGWTGDN----GDPDNFFATLFSCAASEQGSNYSK-WCYKPFED 469 + E+ V +G G P ++S N K + + ++ Sbjct: 215 KTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDT 274 Query: 470 LIQPARATD 478 I+ + Sbjct: 275 PIRVGKKVA 283 >1NW1-A nrPDB Length = 429 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 36/99 (36%), Gaps = 11/99 (11%) Query: 407 AKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKP 466 ++ +E+ Y RA + + WT D + F + + E Sbjct: 297 LVLIDFEYASYNYRA--FDFANHFIEWTIDYDIDEAPFYKIQTENFPE---------NDQ 345 Query: 467 FEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAH 505 + + + ELYK+++ ++ + P + ++H Sbjct: 346 MLEFFLNYLREQGNTRENELYKKSEDLVQETLPFVPVSH 384 >4JZB-A nrPDB Length = 362 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 29/81 (35%), Gaps = 3/81 (3%) Query: 442 NFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPAL 501 F T + +E +NY +I+ + R E Y++A V +Q A Sbjct: 280 TFLTTAPAEKVAEFKANYGS-TDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAA 338 Query: 502 IIAHSTVFEPVRK--EVKGYV 520 + A + F K K Y Sbjct: 339 LEAQNAAFAASVKVLWSKTYK 359 >6AH3-B nrPDB Length = 875 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 20/71 (28%) Query: 212 PFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPA 271 PF Y ++S + +A W KP + F D E + Sbjct: 603 PFTQLGYIENSFYKKEASKTKWDRKPMGKRINFEKIKDIHNTKLPAYSGEIGDFFSSDWR 662 Query: 272 DIARMKQDKSI 282 + ++ Sbjct: 663 FLQILRNGIDY 673 >3UE3-A nrPDB Length = 554 Score = 32.4 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 17/52 (32%), Gaps = 4/52 (7%) Query: 231 GYWGTKPQIDTLVFSITPDASVRYAKLQ----KNECQVMPYPNPADIARMKQ 278 YW K Q D + + D + R + Q + D +K+ Sbjct: 47 DYWDAKTQFDEITAELKKDPNNRRLRRQLPNKNLNLDELADVVGMDRKTLKK 98 >5JFC-L nrPDB Length = 474 Score = 32.4 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 17/125 (13%), Positives = 37/125 (29%), Gaps = 9/125 (7%) Query: 363 LKEAGLEKGFSIDLWAMPVQRPYN-PNARRMAEMIQ---ADWAKVGVQAKIVTYEWGEYL 418 L + G E L Y P R E+++ + ++GV+ + Sbjct: 173 LAKMGYEVTIYEALHQPGGVLIYGIPEFRLPKEIVKKELENLRRLGVKIETNVLVGKTIT 232 Query: 419 KRAKDGEHQTVMMGWTGD----NGDPDNFFATLFSCAASEQGSNYSK-WCYKPFEDLIQP 473 E+ + +G P ++S N K + + ++ I+ Sbjct: 233 FEELREEYDAIFIGTGAGTPRIYPWPGVNLNGIYSANEFLTRINLMKAYKFPEYDTPIKV 292 Query: 474 ARATD 478 + Sbjct: 293 GKRVA 297 >5JOS-A nrPDB Length = 247 Score = 32.1 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 21/142 (14%), Positives = 47/142 (33%), Gaps = 12/142 (8%) Query: 371 GFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVM 430 G + D + P ++ ++ +GV+ + V W + + + M Sbjct: 28 GTTGDYKPFSYRDPDGQYTGFDIDVAKSLAKSLGVKVEFVPTTWPTLMSDLQADKFDIAM 87 Query: 431 MGWT--------GDNGDPDNFF--ATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDH 480 G T D DP F L +++ + + P T++ Sbjct: 88 GGVTVTPERQKKADFSDPYMTFGKTPLVRKEDADKFKSLEDINRPDVRVAVNPG-GTNEK 146 Query: 481 NKRVELYKQAQVVMHDQAPALI 502 R E K+A++ +++ + Sbjct: 147 FAR-EHLKKAKITVYENNVEIF 167 >2NMV-A nrPDB Length = 661 Score = 32.1 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 8/47 (17%), Positives = 24/47 (51%), Gaps = 5/47 (10%) Query: 390 RRMAEMIQADWAKVGVQA-----KIVTYEWGEYLKRAKDGEHQTVMM 431 ++M+E + ++G++ +I T E E ++ + G++ ++ Sbjct: 455 KKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVG 501 >2NVK-X nrPDB Length = 488 Score = 32.1 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 35/111 (31%), Gaps = 10/111 (9%) Query: 330 AGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKAL--------LKEAGLEKGFSIDLWAMPV 381 G IP + ++ D E K L L+ AG KG + M Sbjct: 159 GGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVR 218 Query: 382 QRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMG 432 ++MAE++ A + G+ T ++ DG+ Sbjct: 219 SIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSV--EKQDDGKLLVKYKN 267 >1D9Z-A nrPDB Length = 657 Score = 32.1 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 23/47 (48%), Gaps = 5/47 (10%) Query: 390 RRMAEMIQADWAKVGVQA-----KIVTYEWGEYLKRAKDGEHQTVMM 431 ++MAE + + G++ +I T E E ++ + G++ ++ Sbjct: 454 KKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVG 500 >2GLJ-A nrPDB Length = 461 Score = 31.7 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 35/235 (14%), Positives = 70/235 (29%), Gaps = 29/235 (12%) Query: 188 KEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFD------------GYWGT 235 K YA+ K + P+ TG L + R+ K Y+G Sbjct: 71 KVYANNRGKGLIMFLIGKEPLYTGFKILGAHIDSPRLDLKQNPLYEDTDLAMLETHYYGG 130 Query: 236 KPQIDTLVFS-----ITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGL 290 + + + + E P +DI + + + Sbjct: 131 IKKYQWVTLPLAIHGVIVKKDGTIVNVCVGEDDNDPVFGVSDILVHLASEQLEKKASKVI 190 Query: 291 NVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDV- 349 L+ + PL D + +Q + + I+K + + +S ++ + + Sbjct: 191 EGEDLNILIGSIPLKDGEEKQKVKH-----NIMKILNEKYDISEEDFVSAELEIVPAGKA 245 Query: 350 QDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVG 404 +DY +D G + I + NA++ I D +VG Sbjct: 246 RDYGFDRSMV------MGYGQDDRICAYTSFEAMLEMKNAKKTCITILVDKEEVG 294 >5OL2-B nrPDB Length = 260 Score = 31.7 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 34/97 (35%), Gaps = 1/97 (1%) Query: 241 TLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQ 300 +V I KL N ++ P+ I + +++ +++ Sbjct: 2 NIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEEAIKLKEEMGAHVTVITM 61 Query: 301 KKPLDDVKVRQALTYAVNKDA-IIKAVYQGAGVSAKN 336 P D+ +++AL ++ + + GA A + Sbjct: 62 GPPQADMALKEALAMGADRGILLTDRAFAGADTWATS 98 >4YMX-A nrPDB Length = 260 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 30/92 (32%), Gaps = 4/92 (4%) Query: 401 AKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGW--TGDNGDPDNFFATLFSCAASEQGSN 458 K+GV+ +I ++ + + G V+ G T + +F + N Sbjct: 75 KKLGVKLEIKDMDFKGLIPALQAGRVDMVIAGMTPTAERKKSVDFSDLYYDSRQVVVVKN 134 Query: 459 YSKWCYKPFEDLIQPARATDDHNKRVELYKQA 490 S F+DL A E K+ Sbjct: 135 DSPIS--KFDDLKVKTIAVQIGTTSEEAAKKI 164 >5TUJ-C nrPDB Length = 235 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 34/107 (31%), Gaps = 12/107 (11%) Query: 401 AKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTG--------DNGDPDNF--FATLFSC 450 ++GV+ + V W + + G+ VM G T D DP L Sbjct: 47 KELGVKVEFVPTTWDGIIPALQTGKFDIVMSGMTITPERKKKVDFSDPYMTAGQTILVKK 106 Query: 451 AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQ 497 +++ ++ + + T E +A++ + Sbjct: 107 DNADKIKSFEDLNKP--DVKVAVQLGTTSEQAAKEFLPKAKIRTFEN 151 >6E39-A1 nrPDB Length = 233 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 37/97 (38%), Gaps = 7/97 (7%) Query: 212 PFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDA--SVRYAKLQ-KNECQVMPYP 268 P+ + + Y+ KP +D+ + P+ + + +LQ + Sbjct: 140 PYVNYSSRHTITQPFSYHSRYFTPKPVLDSTIDYFQPNNKRNQLWLRLQTAGNVDHVGLG 199 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLD 305 + + Q+ +I + + V + +N++ PL+ Sbjct: 200 TAFENSIYDQEYNIRV----TMYVQFREFNLKDPPLN 232 >4Q10-A nrPDB Length = 365 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 6/48 (12%), Positives = 21/48 (43%), Gaps = 1/48 (2%) Query: 461 KWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV 508 + F+ Q + + R +L ++++ D P++++ + + Sbjct: 272 WYNNGQFDKRKQETENKFEKDLRKKLVNN-EIILDDDFPSVMVYDAYM 318 >5ZJU-A nrPDB Length = 209 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 37/97 (38%), Gaps = 7/97 (7%) Query: 212 PFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDA--SVRYAKLQ-KNECQVMPYP 268 P+ + + Y+ KP +D+ + P+ + + +LQ + Sbjct: 116 PYVNYSSRHTITQPFSYHSRYFTPKPVLDSTIDYFQPNNKRNQLWLRLQTAGNVDHVGLG 175 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLD 305 + + Q+ +I + + V + +N++ PL+ Sbjct: 176 TAFENSIYDQEYNIRV----TMYVQFREFNLKDPPLN 208 >1I43-A nrPDB Length = 445 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 28/204 (13%), Positives = 63/204 (30%), Gaps = 37/204 (18%) Query: 215 LQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIA 274 + + + + Q D+L S++YA ++ V + Sbjct: 18 VDTTVVNEDVALVENETCNDQNVQFDSL-------PSMKYASFLNSDGSVAIHAG----E 66 Query: 275 RMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA 334 R+ + + + P +N +N + +D + R+A Y G Sbjct: 67 RLGRGIVTDAITTPVVNTSAYFFNKTSELIDFKEKRRA-----------SFEYGRYGNPT 115 Query: 335 KNLIPPTMWGYNDDVQDYTYDPEKAKA-LLKEAGLEKGFSIDLWAMPVQRPYNPNA---R 390 ++ + E A++ LL +G+ + L +P R Sbjct: 116 TVVLEEKISA-----------LEGAESTLLMASGMCASTVMLLALVPAGGHIVTTTDCYR 164 Query: 391 RMAEMIQADWAKVGVQAKIVTYEW 414 + I+ K+G+ A ++ Sbjct: 165 KTRIFIETILPKMGITATVIDPAD 188 >3R0R-A nrPDB Length = 226 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 212 PFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDA--SVRYAKLQ-KNECQVMPYP 268 P+ + + Y+ KP +D+ + P+ + + +LQ + Sbjct: 135 PYVNYSSRHTITQPFSYHSRYFTPKPVLDSTIDYFQPNNKRNQLWLRLQTAGNVDHVGLG 194 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPL 304 + + Q+ +I + + V + +N++ PL Sbjct: 195 TAFENSIYDQEYNIRV----TMYVQFREFNLKDPPL 226 >1MC8-A nrPDB Length = 343 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 6/99 (6%) Query: 338 IPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQ 397 I P + + EK + +EA L+ ++ + R Y A ++ EM+ Sbjct: 73 IKPAYVFDGKPPEFKRKELEKRREAREEAELKWKEALAKGNLEEARKYAQRATKVNEMLI 132 Query: 398 ADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGD 436 D K+ +++ ++ +GE Q M GD Sbjct: 133 EDAKKL---LQLMGIP---IIQAPSEGEAQAAYMASKGD 165 >4ZV2-A nrPDB Length = 233 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 23/56 (41%), Gaps = 8/56 (14%) Query: 394 EMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTG--------DNGDPD 441 ++ +A K+GV+ + ++ + + G+ V+ G T D DP Sbjct: 38 DLAKAIAKKLGVKVEFKPMDFDGIIPALQSGKIDVVIAGMTITEERKKQVDFSDPY 93 >6DZU-A1 nrPDB Length = 189 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 212 PFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDA--SVRYAKLQ-KNECQVMPYP 268 P+ + + Y+ KP +D+ + P+ + + +LQ + Sbjct: 98 PYVNYSSRHTITQPFSYHSRYFTPKPVLDSTIDYFQPNNKRNQLWLRLQTAGNVDHVGLG 157 Query: 269 NPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPL 304 + + Q+ +I + + V + +N++ PL Sbjct: 158 TAFENSIYDQEYNIRV----TMYVQFREFNLKDPPL 189 >5C30-A nrPDB Length = 201 Score = 28.6 bits (62), Expect = 7.6, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 37/128 (28%), Gaps = 8/128 (6%) Query: 242 LVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQK 301 + F P+ Y E A + + NL + +S + Sbjct: 55 VNFHSLPEPERNYNLQMSGETLKTLLALGAHVGMADEKAEDNLKKTKLPKTYMMSNGYKP 114 Query: 302 KPLDDVKVRQ--ALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKA 359 PLD VR A T V++ G V A++ + +P Sbjct: 115 APLDLSHVRLTPAQTTLVDR-----LAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLV 169 Query: 360 -KALLKEA 366 LL EA Sbjct: 170 PYRLLDEA 177 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.309 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,746,407 Number of Sequences: 36641 Number of extensions: 725232 Number of successful extensions: 2792 Number of sequences better than 10.0: 68 Number of HSP's better than 10.0 without gapping: 97 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 2283 Number of HSP's gapped (non-prelim): 128 length of query: 535 length of database: 10,336,785 effective HSP length: 102 effective length of query: 433 effective length of database: 6,599,403 effective search space: 2857541499 effective search space used: 2857541499 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)