BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23843 (543 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3TCF-A nrPDB 1071 0.0 1OLA-A nrPDB 947 0.0 2Z23-A nrPDB 852 0.0 6DQU-A nrPDB 566 e-162 3O9P-A nrPDB 502 e-142 3ZS6-A nrPDB 424 e-119 4GL8-A nrPDB 282 2e-76 6NPO-A nrPDB 214 1e-55 5KZT-A nrPDB 202 3e-52 4FAJ-A nrPDB 177 1e-44 5U4O-A nrPDB 137 1e-32 1UQW-A nrPDB 129 3e-30 3M8U-A nrPDB 123 2e-28 3TPA-A nrPDB 121 8e-28 1DPE-A nrPDB 116 3e-26 6HLX-A nrPDB 115 7e-26 3MW0-A nrPDB 108 5e-24 5F1Q-A nrPDB 108 6e-24 4QFK-H nrPDB 100 2e-21 5ISU-A nrPDB 98 9e-21 4ZE8-A nrPDB 93 4e-19 5ZA4-A nrPDB 91 1e-18 4OER-A nrPDB 91 1e-18 5IPW-A nrPDB 88 8e-18 2WOP-A nrPDB 80 2e-15 3T66-A nrPDB 75 6e-14 3I5O-A nrPDB 75 8e-14 5YQW-A nrPDB 71 9e-13 6EQ0-A nrPDB 69 5e-12 1XOC-A nrPDB 65 9e-11 4PFT-A nrPDB 65 1e-10 1ZTY-A nrPDB 63 4e-10 3DRH-A nrPDB 62 5e-10 4OFL-A nrPDB 60 3e-09 4ONY-A nrPDB 56 5e-08 4PFU-A nrPDB 55 6e-08 5YH8-A nrPDB 53 4e-07 5ICQ-A nrPDB 52 4e-07 4OEU-A nrPDB 49 8e-06 2D5W-A nrPDB 43 5e-04 2GRV-A nrPDB 42 7e-04 4XKN-A nrPDB 41 0.001 2WFN-A nrPDB 30 2.7 3U48-A nrPDB 30 3.2 5HXA-A nrPDB 29 5.9 5TRO-A nrPDB 28 9.1 4GM2-A nrPDB 28 9.7 >3TCF-A nrPDB Length = 524 Score = 1071 bits (2771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV Sbjct: 2 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 61 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG Sbjct: 62 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 121 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT Sbjct: 122 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 181 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE Sbjct: 182 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 241 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD Sbjct: 242 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 301 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT Sbjct: 302 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 361 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY Sbjct: 362 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 421 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV Sbjct: 422 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 481 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH Sbjct: 482 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 518 >1OLA-A nrPDB Length = 517 Score = 947 bits (2449), Expect = 0.0, Method: Compositional matrix adjust. Identities = 443/517 (85%), Positives = 483/517 (93%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 ADVPAGV LA+KQTLVRNNGSEVQSLDPHKIEGVPESN+SRDLFEGLL+SD++GHP+PGV Sbjct: 1 ADVPAGVQLADKQTLVRNNGSEVQSLDPHKIEGVPESNVSRDLFEGLLISDVEGHPSPGV 60 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AE W+NKD KVWTFHLR++AKWSDGTPVTA DFVYSWQR DPNTASPYASYLQYGHIA Sbjct: 61 AEKWENKDFKVWTFHLRENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIAN 120 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 ID+I+ GKKP TDLGVKA+DDHT EVTLSEPVPYFYKLLVHPS SPVPK+A+EKFG+KWT Sbjct: 121 IDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWT 180 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QP NIVTNGAY LK+WVVNERIVLER+P YW+NAKTVINQVTYLPI+SEVTDVNRYRSGE Sbjct: 181 QPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVTYLPISSEVTDVNRYRSGE 240 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMT N+MPIELFQKLKKEIP+EV VDPYLCTYYYEINNQK PFNDVRVRTALKL +DRD Sbjct: 241 IDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLALDRD 300 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVK QG++PAY YTPPYTDGAKL +PEWF WSQ+KRNEEAKKLLAEAG+TADKPLT Sbjct: 301 IIVNKVKNQGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLT 360 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 +LLYNTSDLHKKLAIA +S+WKKN+GVNV L NQEWKTFLDTRHQGTFDVARAGWCADY Sbjct: 361 FDLLYNTSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADY 420 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEPTSFLNTMLS+SS NTAHYKSPAFD ++A+TLKV D+ QR+ LY KAEQQLDKDSAIV Sbjct: 421 NEPTSFLNTMLSDSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIV 480 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PVYYYVNARLVKPWVGGYTGKDPLDN Y +N+YI+KH Sbjct: 481 PVYYYVNARLVKPWVGGYTGKDPLDNIYVKNLYIIKH 517 >2Z23-A nrPDB Length = 517 Score = 852 bits (2202), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/517 (78%), Positives = 448/517 (86%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 A+VP GV LAEKQ LVRNNGSE QSLDPHKIEGVPESNISRDL EGL+++D +G+ PG Sbjct: 1 ANVPTGVQLAEKQVLVRNNGSEPQSLDPHKIEGVPESNISRDLLEGLVINDPNGNIVPGA 60 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AESWDNKD KVWTF++RKDAKWS+G PVTAQDFVYSWQR DP T SPYASYLQY H+ Sbjct: 61 AESWDNKDFKVWTFNIRKDAKWSNGDPVTAQDFVYSWQRLADPKTVSPYASYLQYAHLTN 120 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 ID+I+ GK LGVKA+DDHTLEVTLSEPVPY KLL HP SPV K +EKFGEKWT Sbjct: 121 IDDIITGKAAPDTLGVKALDDHTLEVTLSEPVPYLDKLLAHPLMSPVNKTVVEKFGEKWT 180 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QP N V NGAY LKDW+VNERIVLERSPTYW+NAKTVINQVTYLPI+SEVTDVNRYRSGE Sbjct: 181 QPQNFVGNGAYKLKDWIVNERIVLERSPTYWDNAKTVINQVTYLPISSEVTDVNRYRSGE 240 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMT N+MPIELFQKLKKEIPD+VHVDPYLCTYYYEINNQK PF D RVR ALKLGMDRD Sbjct: 241 IDMTYNNMPIELFQKLKKEIPDQVHVDPYLCTYYYEINNQKAPFTDARVREALKLGMDRD 300 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVK QG++PAYG+TPPYT GA+LT PEWF W+QEKRNE AKKLLAEAGYT D PL Sbjct: 301 IIVNKVKNQGDLPAYGFTPPYTSGAELTPPEWFSWTQEKRNEVAKKLLAEAGYTKDNPLK 360 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 +LLYNTSDLHKKLAIAA+S+WKKN+GV+VKL NQEWKTFLDTRHQGT+DVARA WCADY Sbjct: 361 FSLLYNTSDLHKKLAIAAASIWKKNLGVDVKLENQEWKTFLDTRHQGTYDVARAAWCADY 420 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEP+SFLN MLSNSS NT HYKS FD ++ +TLKV E +R LY +AE QLDKDSAIV Sbjct: 421 NEPSSFLNMMLSNSSNNTTHYKSSVFDKLIEDTLKVKSEKERADLYQQAEIQLDKDSAIV 480 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PV+YYV+ARLVKP+VGGYTGKDPLDN + +++YI+K Sbjct: 481 PVFYYVSARLVKPYVGGYTGKDPLDNMHVKDLYIIKQ 517 >6DQU-A nrPDB Length = 530 Score = 566 bits (1458), Expect = e-162, Method: Compositional matrix adjust. Identities = 279/519 (53%), Positives = 361/519 (69%), Gaps = 4/519 (0%) Query: 29 VPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAE 88 VP G L EKQ +V NNG+E QS DPHK EGVPESN++ L EGL+ SD +G PG AE Sbjct: 4 VPEGTQLDEKQHIVINNGAEPQSFDPHKTEGVPESNVAYQLLEGLVTSDSEGKLQPGAAE 63 Query: 89 SWDNK-DAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGI 147 SW+N D K WTFHLRKDAKWS+G PVTA DFV++W+R VDP TA+PYASYL Y + Sbjct: 64 SWENTPDFKTWTFHLRKDAKWSNGDPVTAHDFVFAWRRLVDPATAAPYASYLSYLQVENA 123 Query: 148 DEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQ 207 +I++GKK +LGV+A DD+T V + PVPY L H S P+P+ +EK G+ W + Sbjct: 124 QDIIDGKKKPAELGVEAKDDYTFVVHATNPVPYAVSLTTHQSLLPLPQKVVEKLGDAWVK 183 Query: 208 PGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEI 267 N V NGAY L + ++NE+I ER+P YWN+ +TVIN T+L I + TDV RYR+G++ Sbjct: 184 KENYVGNGAYKLANHIINEKIEFERNPLYWNDKETVINSATFLAIENPSTDVARYRAGDL 243 Query: 268 DMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDI 327 DMT+ +P E F KLKKE+ EV+V L TY YE+NN+K PF++V +R AL L +DR++ Sbjct: 244 DMTSYGLPPEQFAKLKKELLGEVYVTRTLGTYSYELNNKKAPFDNVNIRKALNLSLDRNV 303 Query: 328 IVNKVKAQGNMPAYGYTPPYT-DGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 I +KV QG P Y +TP Y +G + QP + +RNEEA KLL EAGY+ PL Sbjct: 304 ITDKVLGQGQTPTYVFTPTYIEEGHLIQQPAYSKEPMAQRNEEAIKLLEEAGYSKANPLK 363 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIG--VNVKLVNQEWKTFLDTRHQGTFDVARAGWCA 444 ++LYNT++ HKK+AIAA+S+WK N ++VKL NQEWKT++D+R G +DVARAGW A Sbjct: 364 FSILYNTNENHKKVAIAAASMWKANTKGLIDVKLENQEWKTYIDSRRAGRYDVARAGWHA 423 Query: 445 DYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSA 504 DYN+ T+F N LSNSS NTA Y +P +D MAE+ TD R Y KAE+ L KD Sbjct: 424 DYNQATTFGNYFLSNSSNNTAKYANPEYDKAMAESYAATDAEGRAKAYAKAEEILGKDYG 483 Query: 505 IVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 IVP++ YVN RLVKP+V GY+GKDP D+ Y RN+YI+KH Sbjct: 484 IVPIFNYVNPRLVKPYVKGYSGKDPQDHIYLRNLYIIKH 522 >3O9P-A nrPDB Length = 519 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 252/517 (48%), Positives = 339/517 (65%), Gaps = 2/517 (0%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 A+VP+G LAEKQ LVR+ E SLDP K G+PE + RDLFEGL+ + G PGV Sbjct: 5 AEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGV 64 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 A W + D ++WTF LR +AKW+DGTPVTAQDFVYSWQR VDP T SP+A + I Sbjct: 65 ATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINN 124 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 I++GK LGV A+D HTL++ L +P+P+F L + + PV KA +E G++WT Sbjct: 125 AQAIIDGKATPDQLGVTAVDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVES-GKEWT 183 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 +PGN++ NGAY LK+ VVNE++V+ + YW+NAKTV+ +VT+LPI E RY +G+ Sbjct: 184 KPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGD 243 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 ID+T S P ++QKL K+IP +V+ P L TYYY N QK P D RVR AL + +DR Sbjct: 244 IDITE-SFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRR 302 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 ++ KV G PA+ +TP T G + SQE+ N +AK LL+ AGY KPL Sbjct: 303 LMTEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLK 362 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 + LLYNTS+ H+K+AIA +S+WKKN+GV+VKL NQEWKT++D+R+ G FDV RA W DY Sbjct: 363 LTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDY 422 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEP++FL + S S N + + +PA+D ++A+ R A Y AE+ L + + I Sbjct: 423 NEPSTFLTLLTSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIA 482 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 P+Y Y N RL+KPW+ GY +P D Y+R MYIVKH Sbjct: 483 PIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH 519 >3ZS6-A nrPDB Length = 506 Score = 424 bits (1091), Expect = e-119, Method: Compositional matrix adjust. Identities = 220/509 (43%), Positives = 306/509 (60%), Gaps = 4/509 (0%) Query: 35 LAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKD 94 LA++Q L R +EV+SLDP IE + I DLFEGL D G PGVA++W++K Sbjct: 1 LADQQDLTRQVPAEVESLDPAHIESWTGNTIGLDLFEGLARIDASGAVVPGVAQAWEHKA 60 Query: 95 AKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGK 154 W F LR+DAKWS+G PVTA DFVY+WQR DP T S Y +++ + I+ GK Sbjct: 61 PDTWIFKLRRDAKWSNGQPVTAADFVYAWQRLADPKTGSKYTILVEF--VKNASAIIAGK 118 Query: 155 KPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTN 214 +P DLG++AID +T+EV PV YF +L +PV K A+ KFG+ WT+P NIV+N Sbjct: 119 QPPGDLGIRAIDPYTIEVKTEVPVSYFPELTAMAPLTPVNKDAVAKFGDAWTRPKNIVSN 178 Query: 215 GAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSM 274 G YTL DW N RIV+ +S YWN VI +VTYLPI ++ T + Y++G+ID T S+ Sbjct: 179 GPYTLVDWQPNNRIVMAKSDKYWNARNVVIRKVTYLPIENDETALRMYQAGQIDYTY-SI 237 Query: 275 PIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA 334 P F ++ K+ E+ L TYYY + N P D RVR AL + +DR+I+ +K+ Sbjct: 238 PAGGFGQISKQFGKELRPGLQLATYYYYLKNSDPALKDKRVREALAMVLDREILTSKITQ 297 Query: 335 QGNMPAYGYTPPYTDGAKLT-QPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNT 393 G +P YG P G + P+W W +R + AK LL +AG+ PLT L YNT Sbjct: 298 AGEVPMYGLMPKGVKGVQRPFTPDWASWPMARRVDYAKNLLKQAGHGDANPLTFTLTYNT 357 Query: 394 SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFL 453 +DLHKK+A+ A+S W+ +GV KL N E+K + RH G +AR GW ADYN+ +F Sbjct: 358 NDLHKKVALFAASEWRTKLGVTAKLENVEFKVLMKQRHDGKVQIARDGWFADYNDAMTFF 417 Query: 454 NTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVN 513 + + SS NT Y +P DS++AE + D+ R AL T+A D +VP++ Y Sbjct: 418 DLIRCGSSQNTVGYCNPKVDSLVAEANQKLDDGARAALLTQAHDLAMNDYPMVPLFQYSA 477 Query: 514 ARLVKPWVGGYTGKDPLDNTYTRNMYIVK 542 RLVK +VGGYT + +D +++MY++K Sbjct: 478 DRLVKSYVGGYTLTNYIDMRASQDMYLIK 506 >4GL8-A nrPDB Length = 529 Score = 282 bits (722), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 164/483 (33%), Positives = 268/483 (55%), Gaps = 17/483 (3%) Query: 21 GNVALAADVPAGVTLAEKQTLV--RNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSD- 77 G + P + + + LV N GSE +LD I S I +F G+L D Sbjct: 10 GTLEAQTQGPGSMNESNRNKLVFKLNIGSEPATLDAQLINDTVGSGIVSQMFLGILDGDP 69 Query: 78 LDGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYA 136 G PG+A+SWD + D V+TFHLR + WSDG +TA+ S+ R +D T S + Sbjct: 70 RTGGYRPGLAKSWDISDDGVVYTFHLRDNLVWSDGVSITAEGIRKSYLRILDKETGSSFV 129 Query: 137 SYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA 196 + ++ I +E +GK ++LG+KA+D+ TLE+TL P PYF +LVH + PVP Sbjct: 130 NMIK-SVIKNAEEYFDGKANESELGIKALDEKTLEITLKSPKPYFLDMLVHQTFIPVPMH 188 Query: 197 AIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEV 256 IEK+G++WT P N+V +G + LK V+NE++VLE++ Y+N+ V++ + + + + Sbjct: 189 VIEKYGQRWTDPENMVVSGPFKLKSRVLNEKVVLEKNNKYYNSKDVVLDSIIFFVTDNSI 248 Query: 257 TDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVR 316 T N Y + E+D ++P +L + LK + D+ + T +Y +N + P ++V+VR Sbjct: 249 TAYNMYLNDELDAIFKNVPPDLLKDLK--LRDDYYSMGINSTSFYSLNMKVKPLDNVKVR 306 Query: 317 TALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE 376 AL +DR + V ++P TP Y D + + F E AKKLLA+ Sbjct: 307 KALSFAIDRKTLTESVLNDSSIPTRRATPDYIDYSYKSNLSLFD------AEMAKKLLAD 360 Query: 377 AGY--TADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGT 434 AGY + PL + + YNTSD +K+A + WKKN+ +NV+L N+EW T++++R G Sbjct: 361 AGYPNGNNFPL-LKVKYNTSDSQRKIAEFIQNQWKKNLNINVQLENEEWSTYINSRVNGN 419 Query: 435 FDVARAGWCADYNEPTSFLNTMLS-NSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYT 493 +++ R+GW DY +P +FL+ + N+S ++ Y + +D ++ ++ D +R + Sbjct: 420 YEIIRSGWSGDYADPMTFLSIFQTENTSFSSYGYSNSEYDELLIKSDNERDIFKRQEILK 479 Query: 494 KAE 496 KAE Sbjct: 480 KAE 482 >6NPO-A nrPDB Length = 546 Score = 214 bits (544), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 158/516 (30%), Positives = 253/516 (49%), Gaps = 20/516 (3%) Query: 22 NVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGH 81 N + D + LA KQ + E+ ++D K S I + EGL D + Sbjct: 17 NSSSGGDSKSEEKLAAKQVFNKTENQEIPTMDTSKSTDTLGSQILGNTMEGLYRLDKENK 76 Query: 82 PAPGVAES-WDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQ 140 P P AES ++D K +TF LRKDAKWS+G VTA+DFV++WQR +DP TA+ YA ++ Sbjct: 77 PIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDSVTAKDFVFAWQRLLDPKTAAEYA-FIA 135 Query: 141 YGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEK 200 + I + + +G+KP+T+LGVKA+DD TLEV L + VPYF L+ PS P+ + +++ Sbjct: 136 F-PIKNAEAVNKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKE 194 Query: 201 FGEKW-TQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDV 259 G+K+ + V NG + L DW + L+++ YW+ ++++ Y + T+V Sbjct: 195 KGDKYGLESDTTVYNGPFVLTDWKHEQGWKLKKNDQYWDKKTVKLDEINYSVVKEPATNV 254 Query: 260 NRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINN----QKPPFNDVRV 315 N Y SG+ID S+ F + +E V T++ +N Q P ++ Sbjct: 255 NLYDSGQIDF---SLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGGQDTPLKSKKL 311 Query: 316 RTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYT----DGAKLTQPEWFGWSQEKRNEEAK 371 R A+ L +D+ + N + G+ PA P DG + G + + A Sbjct: 312 REAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVKPDAKKAAAA 371 Query: 372 KLLAEAGYTADKPLTINLL-YNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTR 430 A+ D+ +TI L Y+T + K + K GV V + Q +K L Sbjct: 372 WEEAKKELGKDQ-VTIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLE 430 Query: 431 HQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIM--AETLKVTDEAQR 488 +D++ GW DY +P ++L+ S S N + +D I+ A +TD +R Sbjct: 431 SDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQMSFSDQKYDEIIKKAGGELMTDAKKR 490 Query: 489 TALYTKAEQ-QLDKDSAIVPVYYYVNARLVKPWVGG 523 KAE+ L++D A+VP+Y + ++KP V G Sbjct: 491 WEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKG 526 >5KZT-A nrPDB Length = 536 Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 165/525 (31%), Positives = 257/525 (48%), Gaps = 30/525 (5%) Query: 38 KQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPA-PGVAESWDNKDAK 96 +Q L + + S D K + N+ EGL D DG PA G AE D K Sbjct: 14 EQVLNLTESALIPSADSTKADDQVGLNVVNQTNEGLYALDKDGIPAIAGAAEEPKISDDK 73 Query: 97 -VWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKK 155 V+T LR+DAKWS+G PVTA D+VYSW+R+VDPNTA+ Y SYL + I +I+ GKK Sbjct: 74 TVYTIKLREDAKWSNGDPVTANDYVYSWRRAVDPNTAATY-SYL-FDAIKNGGDIVAGKK 131 Query: 156 PITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQ-PGNIVTN 214 +LG+KA+DD+TLEVTLS+P Y L P+ P+ + + + GEK+ Q N++ N Sbjct: 132 KPEELGIKAVDDYTLEVTLSKPTAYINSLFAFPTFFPLNEKFVTEKGEKYAQNSDNMLFN 191 Query: 215 GAYTLKDWV-VNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNS 273 G + LKDW N++ ++ YW+ K + Q+ + T +N Y + ++D T S Sbjct: 192 GPFELKDWTGTNKKWTYVKNDKYWDKDKVKLKQINVQVVQDSGTGLNLYNTDKVDRTVLS 251 Query: 274 MPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPP----FNDVRVRTALKLGMDRDIIV 329 + K D V V+ T+Y + N ++ F + +R A+ L +D+ Sbjct: 252 AD---YAAQNKNNKDYVTVNN-SSTFYIKFNQKRAGKDTVFANKNIRKAIALAIDKQSYT 307 Query: 330 NKVKAQGNMPAYGYTPP---YTDGAKLTQPEWFGWSQEKRNEEAKKL----LAEAGYTAD 382 + V G+ PA P + G K + G E +EA+K L E G Sbjct: 308 DTVLKNGSKPANNLVPEGFTFDPGNKEDYTKESGKHLEYDVKEAQKAWKAGLKELGVN-- 365 Query: 383 KPLTINLLYNTSDLHKKLAIAASSLWKKNI-GVNVKLVNQEWKTFLDTRHQGTFDVARAG 441 +T+ + ++ +K + +KN+ G+ VKL N +K L +D + +G Sbjct: 366 -EITVEFTSDDTENARKSSEFIQDQLQKNLDGLTVKLKNVPFKVRLQNDQNQDYDFSMSG 424 Query: 442 WCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIM--AETLKVTDEAQRTALYTKAEQ-Q 498 W DY +P++FL+ +++ + N Y + +D I+ A D+ +R KAE+ Sbjct: 425 WGPDYQDPSTFLDLFVTDGAQNRMSYSNKDYDKILNDASVTYAADDQKRWDEMVKAEKIL 484 Query: 499 LDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYT-RNMYIVK 542 L D AI P+Y A L K ++ K+P YT + Y+ K Sbjct: 485 LTDDVAIQPLYQRSTAYLQKDYIKNLQ-KNPFGPDYTYKETYLTK 528 >4FAJ-A nrPDB Length = 564 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 144/538 (26%), Positives = 244/538 (45%), Gaps = 31/538 (5%) Query: 1 MTNITKRSLVAAGVLAALMA--GNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIE 58 M K + G+L ++A G D +Q G+ VQSLDP Sbjct: 20 MKKYKKFCFLGIGLLPLVLASCGTNTATKDSQDATEKKVEQVATLTAGTPVQSLDPATAV 79 Query: 59 GVPESNISRDLFEGLLVSDLDGHPAPGVAESWD--NKDAKVWTFHLRKDAKWSDGTPVTA 116 + ++ EGL D P P +A + + K +T +R AKWSDGT +TA Sbjct: 80 DQTSITLLANVMEGLYRLDEKNQPQPAIAAGQPKVSNNGKTYTIVIRDGAKWSDGTQITA 139 Query: 117 QDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSE 176 DFV +WQR VDP T SP + I EI GK+ L VK+I + TLE+ L E Sbjct: 140 SDFVAAWQRVVDPKTVSPNVEL--FSAIKNAKEIASGKQAKDTLAVKSIGEKTLEIELVE 197 Query: 177 PVPYFYKLLVHPSTSPVPKAAIEKFGEKW-TQPGNIVTNGAYTLKDWV---VNERIVLER 232 P PYF LL + PV + AI+++G+ + IVTNGA+ L + +++ + + Sbjct: 198 PTPYFTDLLSLTAYYPVQQKAIKEYGKDYGVSQKAIVTNGAFNLTNLEGVGTSDKWTISK 257 Query: 233 SPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHV 292 + YW+ ++++ + + T +N Y G++D + E ++ KK+ E Sbjct: 258 NKEYWDQKDVSMDKINFQVVKEINTGINLYNDGQLDEA--PLAGEYAKQYKKD--KEYST 313 Query: 293 DPYLCTYYYEINN--QKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDG 350 T + E+N + + VR A+ +DR+ +V K+ G++ + G P Sbjct: 314 TLMANTMFLEMNQTGENKLLQNKNVRKAINYAIDRESLVKKLLDNGSVASVGVVPKEMAF 373 Query: 351 AKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPL------TINLLYNTSDLHKKLAIAA 404 + + + ++ EK E KK E A K + +++LL + + KK Sbjct: 374 NPVNKKD---FANEKLVEFNKKQAEEYWDKAKKEIDLSKNTSLDLLVSDGEFEKKAGEFL 430 Query: 405 SSLWKKNI-GVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMN 463 + ++ G+ V + F++ + F ++ +GW ADY +P SFL +NS MN Sbjct: 431 QGQLQDSLEGLKVTVTPIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMN 490 Query: 464 TAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWV 521 Y + +D ++ ++ ++R KAE+ L D +VP++ A+L K + Sbjct: 491 HGGYSNKNYDELLKDS-----SSKRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKI 543 >5U4O-A nrPDB Length = 521 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 131/522 (25%), Positives = 226/522 (43%), Gaps = 55/522 (10%) Query: 6 KRSLVAAGV----LAALMAG---NVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIE 58 KR LV+ + L+ +AG N + E L S+ +LDPH I Sbjct: 4 KRGLVSCFIAILCLSVFLAGCSSNAKTGNEGSGSKGTKEGGVLTIARLSDADNLDPHFIT 63 Query: 59 GVPESNIS-RDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQ 117 +P +++ ++E L+ D + P +A+ W D W F L++ + DG P A+ Sbjct: 64 NIPSASVVYHKVYENLVQRDKNMDFKPMLAKEWKQIDDLNWEFKLQQGVTFQDGAPFNAE 123 Query: 118 DFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEP 177 +++R +DP S A+ I EI K ID++T++ L P Sbjct: 124 AVKKNFERVLDPKVGSNRATVYSM-----IQEI------------KVIDEYTVQFILKYP 166 Query: 178 VPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYW 237 + S + AI++ G+ Q + V G YT K W E I LE++ YW Sbjct: 167 YSPLLSIFASNEGSILSPKAIDEKGKGLAQ--HPVGTGPYTFKSWKPGEEIRLEKNKNYW 224 Query: 238 NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLC 297 K +++V + + + T + + E + N +P+ +++K E+ + L Sbjct: 225 GE-KAKVDEVVFKVVPEDATRIGMIETSEAHIAEN-LPVTEVERVKNSPSMELIENEGLG 282 Query: 298 TYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPE 357 Y N +K PF++ VR A+ ++ I+ V Y T+ + P+ Sbjct: 283 VEYIGFNVEKKPFDNPLVRQAIAHAIETKGILKGV----------YNNVGTEINSVMTPK 332 Query: 358 WFGWSQEKRNEE-----AKKLLAEAGYTADKPLTINLLYNTSDLHKKLA-IAASSLWKKN 411 FG++++ + + AKKLLA+AGY TI N S + L + S L K Sbjct: 333 VFGYTKDVKGYKYDINTAKKLLADAGYPNGFKTTI--WTNDSKVRMALVEVIQSQL--KG 388 Query: 412 IGVNVKLVNQEWKTFLDTRHQGTFDVARAGWC-----ADYNEPTSFLNTMLSNSSMNTAH 466 IGV+V++ E+ FL ++ + GW DYN+ F ++ ++ N Sbjct: 389 IGVDVEIKVMEYGAFLAATNKSEHAMFVGGWGNATGDGDYNQYNLF-HSSSHGATGNQFF 447 Query: 467 YKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV 508 Y +P D ++ E K DE +R LY + ++ KD+ +VP+ Sbjct: 448 YSNPEVDKLIEEARKEKDETKRKELYKQLQEIELKDALLVPI 489 >1UQW-A nrPDB Length = 509 Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 122/473 (25%), Positives = 207/473 (43%), Gaps = 37/473 (7%) Query: 46 GSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAKVWTFHLRK 104 GS +LDP+ +++ ++GL D + +AES+ + D +T LR+ Sbjct: 32 GSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLRE 91 Query: 105 DAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKA 164 K+ DGT A + R+ DP A+ + Y +IA + A Sbjct: 92 GIKFQDGTDFNAAAVKANLDRASDP--ANHLKRHNLYKNIAKTE---------------A 134 Query: 165 IDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFG-EKWTQPGNIVTNGAYTLKDWV 223 ID T+++TL +P F +L HP+T+ + AA+EK+G E P V G Y L W Sbjct: 135 IDPTTVKITLKQPFSAFINILAHPATAMISPAALEKYGKEIGFYP---VGTGPYELDTWN 191 Query: 224 VNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLK 283 + + +++ YW ++ +T+ P+A T ++GE +P E L+ Sbjct: 192 QTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQFA-FPIPYEQATLLE 250 Query: 284 KEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGY 343 K E+ P + Y +N + PF++ +VR AL ++R +V A PA G Sbjct: 251 KNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYATPATGV 310 Query: 344 TPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIA 403 PP A+ +P W + +A++LL EAGY T+ +N S K L Sbjct: 311 VPPSIAYAQSYKP----WPYDPV--KARELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFT 364 Query: 404 ASSLWKKNIGVNVKLVNQEWKTF-LDTRHQGTFDVAR--AGWCADYNEPTSFLNTMLSNS 460 L + I V ++ + ++ + Q V GW A E L+ + ++ Sbjct: 365 QQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEADWALSPLFASQ 424 Query: 461 S-----MNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV 508 + NTA Y + D +A+ LK D A++T LY A+ + ++S +P+ Sbjct: 425 NWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPWIPL 477 >3M8U-A nrPDB Length = 522 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 115/467 (24%), Positives = 209/467 (44%), Gaps = 31/467 (6%) Query: 84 PGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVT------AQDFVYSWQRSVDPNTASPYA 136 P +AESW + D +TF+LRK K+ T A D V+S+QR +DPN Sbjct: 50 PALAESWTVSDDGLTYTFNLRKGVKFHSNKEFTPSRDFNADDVVFSFQRQLDPNHPYHNV 109 Query: 137 SYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA 196 S Y + + K V+ +D HT+++TL+ F L S Sbjct: 110 SKATYPYFKAM------KFSTLLKSVEKVDMHTVKITLNRQDATFLASLGMDFISIYSAE 163 Query: 197 AIEKF---GEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIA 253 +K G+ T + G + + V+++ YW K I+++ + + Sbjct: 164 YADKMLAAGKPETIDTTPIGTGPFLFAGYQVDQKSRYLAHKEYWK-GKADIDRLIFEIVP 222 Query: 254 SEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDV 313 + ++G D+ + +L +K+K + +H L Y N +K PF++V Sbjct: 223 DATARYAKLQAGACDLIDFPNAADL-EKMKTDPKVNLHSQSGLNIAYIAFNTEKAPFDNV 281 Query: 314 RVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKL 373 +VR AL +D++ I++ V + A PP G E G+ E E+AK+L Sbjct: 282 KVRQALNYAVDKNAIIDAVYRGAGVAAKNPLPPTIWG---YNNEITGY--EYSPEKAKQL 336 Query: 374 LAEAGYT--ADKPLTINLLYNTSDLH-KKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTR 430 L EAG+ + + + + S+ + +++A S W+K +GV KLV+ EW ++ Sbjct: 337 LKEAGFENGFETDIWVQPVVRASNPNPRRMAELVQSDWEK-VGVKSKLVSYEWGDYIKRT 395 Query: 431 HQGTFDVARAGWCADYNEPTSFLNTMLSNSSM---NTAHYKSPAFDSIMAETLKVTDEAQ 487 G GW D +P +FL+ + + ++ N A +K+P D+++ + + ++D+A+ Sbjct: 396 KAGELTAGTYGWSGDNGDPDNFLSPLFGSENVGNSNYARFKNPELDALLHKAVGLSDKAE 455 Query: 488 RTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTY 534 R +Y +A+ L + + + V + +N V Y + P TY Sbjct: 456 RAKIYEQAQVLLKEQAPWINVAHSINFAPTSKRVQDYK-QSPFGYTY 501 >3TPA-A nrPDB Length = 521 Score = 121 bits (304), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 120/462 (25%), Positives = 207/462 (44%), Gaps = 40/462 (8%) Query: 84 PGVAESWD-NKDAKVWTFHLRKDAKW------SDGTPVTAQDFVYSWQRSVDPNTASPY- 135 PG+AE W+ ++D V+TF+LR++ K+ S P+ A D V+S+QR D N PY Sbjct: 55 PGLAERWEISEDGLVYTFYLRQNVKFHSNKTFSPTRPLNADDVVFSFQRQADKN--HPYH 112 Query: 136 ---ASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSP 192 A Y + + IL+ V+ +DD+T+++TL++P F + S Sbjct: 113 NVSAGTYFYFNWMNLPSILKS--------VEKVDDYTVKITLNKPNTPFITTVAMDFLSI 164 Query: 193 VPKAAIEKF---GEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTY 249 K ++ G+ T + G + + + + + YW K I ++ + Sbjct: 165 YSKEYADQLLAQGKPETLDQQPIGTGPFIFQTNQTDHAVRYTANVDYWK-GKADIERLIF 223 Query: 250 LPIASEVTDVNRYRSGEIDMTNNSMP-IELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP 308 T + ++GE D+ + P I ++KK+ + L Y +N KP Sbjct: 224 SITPDAGTRYAKLKAGECDVID--FPNISDIAQMKKDPQINLLEREGLNLAYIGLNTTKP 281 Query: 309 PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNE 368 N+V+VR AL D+ IV+ V G A T P+ D P + E E Sbjct: 282 ELNNVKVRQALHHATDKKAIVDAVYQGGGTVA---TNPFPDAVLGYNPHLPQY--EFNLE 336 Query: 369 EAKKLLAEAGY--TADKPLTINLLYNTSDLH-KKLAIAASSLWKKNIGVNVKLVNQEWKT 425 +AK LLAEAGY + + + + S+ + ++ A + W K IGV KLV EW Sbjct: 337 KAKALLAEAGYPNGFETEIWVQPVVRPSNPNPRRTAEIIQADWAK-IGVKAKLVTHEWAD 395 Query: 426 FLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSM---NTAHYKSPAFDSIMAETLKV 482 F +G F GW + +P +FL + S +++ N + + F++++A ++ Sbjct: 396 FNKRTREGEFAAGTYGWTSRNGDPDNFLFPLFSQANIPGTNYSRWTDEKFEALLASAAQI 455 Query: 483 TDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGY 524 D R LY +A + ++S I+P + +N + V G+ Sbjct: 456 QDTQTRAKLYQQAVEIFQQNSPIIPFAHSINYVPLNKRVQGF 497 >1DPE-A nrPDB Length = 507 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 122/488 (25%), Positives = 206/488 (42%), Gaps = 60/488 (12%) Query: 84 PGVAESWD-NKDAKVWTFHLRKDAKWSDGTP------VTAQDFVYSWQRSVDPNTASPY- 135 PG+AE W+ ++D K +TFHLRK KW D + A D V+S+ R N +PY Sbjct: 48 PGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQ--KNAQNPYH 105 Query: 136 ----ASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTS 191 SY +Y G+ E++ VK +DD+T++ L+ P F L S Sbjct: 106 KVSGGSY-EYFEGMGLPELISE--------VKKVDDNTVQFVLTRPEAPFLADLAMDFAS 156 Query: 192 PVPKA---AIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVT 248 + K A+ K G N + G + L+ + + RI + YW K I+ + Sbjct: 157 ILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLV 215 Query: 249 YLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP 308 + + + E + P ++ ++K++ + P L Y N QK Sbjct: 216 FSITPDASVRYAKLQKNECQVMPYPNPADI-ARMKQDKSINLMEMPGLNVGYLSYNVQKK 274 Query: 309 PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRN- 367 P +DV+VR AL +++D I+ V + A PP +G++ + ++ Sbjct: 275 PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTM----------WGYNDDVQDY 324 Query: 368 ----EEAKKLLAEAGYTADKPLTINLL-------YNTSDLHKKLAIAASSLWKKNIGVNV 416 E+AK LL EAG +K +I+L YN + +++A + W K +GV Sbjct: 325 TYDPEKAKALLKEAGL--EKGFSIDLWAMPVQRPYNPN--ARRMAEMIQADWAK-VGVQA 379 Query: 417 KLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSS----MNTAHYKSPAF 472 K+V EW +L G GW D +P +F T S ++ N + + F Sbjct: 380 KIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATEFSCAASEQGSNYSKWCYKPF 439 Query: 473 DSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDN 532 + ++ D +R LY +A+ + + + + + V+ V GY DPL Sbjct: 440 EDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGK 498 Query: 533 TYTRNMYI 540 + N+ I Sbjct: 499 HHFENVSI 506 >6HLX-A nrPDB Length = 492 Score = 115 bits (287), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 122/503 (24%), Positives = 215/503 (42%), Gaps = 56/503 (11%) Query: 40 TLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAKVW 98 TL E +LD G + + GL+ +DG +P +AES++ + DAK + Sbjct: 3 TLYFGLSGEPSTLDTVVQPGTSGRTVKLAIHRGLVNYGIDGKISPELAESYEVSPDAKEF 62 Query: 99 TFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPIT 158 TFHLR+ AK+ DGT VT+ D S +R +DP + + + ++ I +I Sbjct: 63 TFHLRQ-AKFHDGTTVTSADVKASLERILDPKGKASFRN-----ELSSISKI-------- 108 Query: 159 DLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT 218 + D+ T+++TLS P L P + VP A + K + V G + Sbjct: 109 ----ETPDEKTVKLTLSTPSVAMIDYLALPESVIVPAAWLAKNADNPNAAP--VGAGPFK 162 Query: 219 LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIEL 278 W I +++ Y+ K +++V Y+ + E T VN +SG++D+ + +P + Sbjct: 163 FAGWTRGREITVKKFDDYYKKGKPDLDEVHYVFYSDENTRVNALKSGDVDII-DYVPAKD 221 Query: 279 FQKLKKEIPDEV--HVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQG 336 + K ++ + P++ + N + PF+ VR A+ +DR I+N Sbjct: 222 AADIAKGPETQLLRNTGPFMGL---QFNTKFEPFSKPEVRQAIAYAVDRSAIINTAFNGL 278 Query: 337 NMPAYGYTPPYTDGAKLTQPEWFGWSQEKRN------EEAKKLLAEAGYTADKPLTINLL 390 P +G P + G+S K N E+AK LLA+AGY + LL Sbjct: 279 GSPIFGIAIP---------KGYMGYSDAKANYFSHHVEKAKALLAKAGYP--NGFEVRLL 327 Query: 391 YNTS-DLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEP 449 + + AIA S K IG+ VKL +W + + G +D G + + Sbjct: 328 ATSQYSFQQNTAIAIQSELAK-IGIKVKLDLPDWASRMAKASTGDYDFTVMGSLGEITDA 386 Query: 450 TSFLNTMLSNSSM----NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAI 505 N + N+ ++ + ++ + D+A+R +Y + +D+ + Sbjct: 387 DWLSNYYYGGDKLVRTNNSPYFNDQQINDLLDKGRATVDKAERVKIY---DAFVDRALEL 443 Query: 506 VPVYYYV---NARLVKPWVGGYT 525 P+ Y++ VK V G+T Sbjct: 444 SPLVYFMWREQNYAVKKGVTGFT 466 >3MW0-A nrPDB Length = 502 Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 124/500 (24%), Positives = 209/500 (41%), Gaps = 58/500 (11%) Query: 49 VQSLDPHKIEGVPESNISRDL-FEGLLVSDLDGHPAPGVAESW-DNKDAKVWTFHLRKDA 106 V L+PH P ++ + +E L+ DG P +A+SW ++D K WTF LR D Sbjct: 14 VGPLNPHLY--TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDV 71 Query: 107 KWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAID 166 K+S+G P A+ +++ +D + LE I D VKA+ Sbjct: 72 KFSNGEPFDAEAAAENFRAVLDNRQRHAW---------------LELANQIVD--VKALS 114 Query: 167 DHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPG--NIVTNGAYTLKDWVV 224 L++TL F + L P P A +F T G + G + L++ + Sbjct: 115 KTELQITLKSAYYPFLQELALP--RPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKL 172 Query: 225 NERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM---TNNSMPIELFQK 281 N+ V R+ YW K I ++T+ I T + +G+ID+ +P++ F + Sbjct: 173 NQYDVFVRNENYWGE-KPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFAR 231 Query: 282 LKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMD-RDIIVNKVKAQGNMPA 340 + + + T +N K P N++ VR AL ++ + +I N + + Sbjct: 232 FSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVAD 291 Query: 341 YGYTP--PYTD-GAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA----------DKPLTI 387 + P PY + G K +Q + ++AK LL +AG+T +PL I Sbjct: 292 TLFAPSVPYANLGLKPSQYD---------PQKAKALLEKAGWTLPAGKDIREKNGQPLRI 342 Query: 388 NLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD-VARAGWCADY 446 L + +D K + IG +V L+ +E + + G F + W A Y Sbjct: 343 ELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPY 402 Query: 447 NEPTSFLNTMLSNSSMNTAHYKS----PAFDSIMAETLKVTDEAQRTALYTKAEQQLDKD 502 + P +FL++M S + + P D + E L DE QR ALY +L + Sbjct: 403 D-PHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDE 461 Query: 503 SAIVPVYYYVNARLVKPWVG 522 + +P+ Y + KP +G Sbjct: 462 AVYLPISYISMMVVSKPELG 481 >5F1Q-A nrPDB Length = 543 Score = 108 bits (270), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 114/479 (23%), Positives = 202/479 (42%), Gaps = 51/479 (10%) Query: 84 PGVAESWD-NKDAKVWTFHLRKDAKWSDGTPV------TAQDFVYSWQRSVDPNTASPYA 136 P +AE W+ ++D K +TF+LRK KW D A D +YS+ R D Sbjct: 76 PSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKV 135 Query: 137 SYLQYGHIAGIDEILEGKKPITDL--GVKAIDDHTLEVTLSEP-VPYFYKLLVHPSTSPV 193 S Y + G+ + DL V +DD+T+ L+ P P+ L + ++ Sbjct: 136 SGGSYEYFQGMG--------MGDLITNVVKVDDNTVRFELTRPESPFLADLAMDFASILS 187 Query: 194 PKAA--IEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLP 251 + A + K G N + G + L+ + + RI+ + P +W K I+++ + Sbjct: 188 AEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGT-KPKIDRLVFSI 246 Query: 252 IASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFN 311 + + E + P ++ ++K++ + P L Y N +K P + Sbjct: 247 TPDASVRYAKLQKNECQIMPYPNPADI-ARMKEDKTINLMEQPGLNVGYLSFNIEKKPLD 305 Query: 312 DVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPP----YTDGAKLTQPEWFGWSQEKRN 367 +++VR AL + +++D I++ V A PP Y D K + + K Sbjct: 306 NLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKD-----YAYDPAK-- 358 Query: 368 EEAKKLLAEAG----YTADK-PLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQE 422 AK+LL EAG ++ D + + YN + +++A S W K IGV K+V E Sbjct: 359 --AKELLKEAGLPDGFSIDLWAMPVQRPYNPN--ARRMAEMIQSDWAK-IGVKAKIVTYE 413 Query: 423 WKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSM----NTAHYKSPAFDSIMAE 478 W +L G + GW D +P +F T+ S + N + + F+ ++ Sbjct: 414 WGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQP 473 Query: 479 TLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYT----GKDPLDNT 533 D +R ALY +A+ +++ + + + + V+ V GY GK DN Sbjct: 474 ARAEADHDKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNV 532 >4QFK-H nrPDB Length = 541 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 115/473 (24%), Positives = 202/473 (42%), Gaps = 54/473 (11%) Query: 65 ISRDLFEGLLVSD-LDGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVT------A 116 I+ L++ L+ D + +A W +KD K TF LRK K+ T A Sbjct: 56 IANQLYDRLISIDPVTAEFKSELATDWKISKDGKSVTFTLRKGVKFHTTAYFTPTREFNA 115 Query: 117 QDFVYSWQRSVDPNTASPY-----ASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLE 171 D ++++ R D +PY A+Y Y GID+++ ++D V+ + Sbjct: 116 DDVIFTFSRLFD--VYNPYHFVGDANY-PYFQSVGIDQLIRKIVRVSDHQVRFELFNAES 172 Query: 172 VTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLE 231 L+ F +L + E +++ V G Y K++ + + Sbjct: 173 SFLANMATDFAVVLSKEYAMALKANNQENLFDQYP-----VGTGPYIYKEYRRDHLVRFY 227 Query: 232 RSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVH 291 ++ YW + + + Q+ Y + T + + + E D+T + +L L + V Sbjct: 228 KNADYWKH-EVALEQLVYDITPNGTTRIAKILTKECDVTAHPSSAQL-SILAQRDDINVE 285 Query: 292 VDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGA 351 + L Y+ N ++PPF++++VR AL +D + I+ V + A PP + Sbjct: 286 RETNLNIGYWAFNTERPPFDNLKVRQALVHAIDIEKIMQAVYYGNGLRARSILPPTS--- 342 Query: 352 KLTQPEWFGWSQEKRN-------EEAKKLLAEAGYTADKPLTI-----NLLYNTSDLHKK 399 W+ E + + AKKLL EAGY ++I + +YN + +K Sbjct: 343 ---------WAFEPQKNMPIFDPQLAKKLLTEAGYEKGFDMSIWAMPVSRIYNPN--ARK 391 Query: 400 LAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSN 459 +A S +K IGVNV +V EW TF+ + D GW AD +P +F + +LS Sbjct: 392 MAELMQSDLRK-IGVNVNIVEYEWNTFIQRIGEHRHDSVLLGWAADTPDPDNFFSPLLSC 450 Query: 460 ----SSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV 508 S N A++ +P FD ++ + L TD R Y A+ + + + P+ Sbjct: 451 TATFSGKNPANWCNPEFDLLLTKALDTTDLNLRKQYYDAAQSMIIEQLPLYPI 503 >5ISU-A nrPDB Length = 502 Score = 97.8 bits (242), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 119/476 (25%), Positives = 210/476 (44%), Gaps = 49/476 (10%) Query: 77 DLDGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPY 135 ++DG PA +A+S D + D +T L+ W DG P+TA D V++ +D SP Sbjct: 55 EVDGKPA--LAKSLDISDDNLTYTVKLKDGLTWHDGKPLTADDVVFTVNSILDTKQNSP- 111 Query: 136 ASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPK 195 G+ D KP+ V+A+DD T++ TL P F + + P+PK Sbjct: 112 ----NRGNFVFDD------KPVK---VEAVDDTTVKFTLPTVAPAFENTI--KTFFPIPK 156 Query: 196 AAIEKFG--EKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIA 253 E EK + N + +G Y ++ E + LER Y+ + K +++VT+ Sbjct: 157 HIFEGVENIEKSDKNKNPIGSGPYKFVEYKTGEYVSLERFNDYF-DGKPKLDKVTFRITK 215 Query: 254 SEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDV 313 + ++GEI++ S+ K++K + P Y N +P Sbjct: 216 DQNAANLALQNGEINL--KSIQPSDRNKVEKASAVNIITYPENRLSYATFNENQPALKSK 273 Query: 314 RVRTALKLGMDRDIIVNKVKAQGNMPAYG---YTPPYTDGAKLTQ-PEWFGWSQEKRNEE 369 +R AL +DR+ I++ AYG Y P + + LT+ ++F E +++ Sbjct: 274 ELRQALSYALDREEIID--------AAYGSDEYAKPAS--SFLTENTKYFTDKVETYDQD 323 Query: 370 ---AKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLV----NQE 422 AKKL+ E+G+ + LT+ L N S + +A+ +K+ IGV + L N Sbjct: 324 IAKAKKLVKESGFDTSQKLTVYYL-NNSKSQESIALYLQQQYKE-IGVTLDLKPTDPNAL 381 Query: 423 WKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKV 482 LD R + +A G+ N+P ++ + LS++ N ++Y + D++ + Sbjct: 382 SNITLD-RKNADYSIALNGYIMG-NDPDAYKSLYLSDAPYNYSNYHNKDLDALWEKGAVT 439 Query: 483 TDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNM 538 D+ +R +Y K + + D+ I P+ Y + GG P T R++ Sbjct: 440 ADDKERQEIYEKIQNTIADDAVIYPISYDNAVLALDSRYGGQKAATPQPVTMFRDL 495 >4ZE8-A nrPDB Length = 499 Score = 92.8 bits (229), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 106/376 (28%), Positives = 170/376 (45%), Gaps = 34/376 (9%) Query: 49 VQSLDPHKIEGVPESNISRDLF-EGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAK 107 + ++ P + + ++ I+RD F +G + +D PA +AESW+ D K F LR+ Sbjct: 24 ISNVGPRIVNQIFDTLIARDFFAKGAPGNAIDLVPA--LAESWERIDEKSVRFKLRQKVM 81 Query: 108 WSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDD 167 + DG +TA D Y+ ++S +G A I +I GK D ++D Sbjct: 82 FHDGVELTADDVAYT------------FSSERLWGPEA-IKKIPLGKSYSLDFDEPVVED 128 Query: 168 HTLEVTLSEPVP-YFYKLLVHPSTSP-VPKAAIEKFGEKWTQPGNI-VTNGAYTLKDWVV 224 VTL P Y + V S VPK +K G GN V G Y ++V Sbjct: 129 K-YTVTLRTKTPSYLIETFVASWMSRIVPKEYYKKLGA--VDFGNKPVGTGPYKFVEFVA 185 Query: 225 NERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKK 284 +R+VLE + YW K +++TY +A T V SGE D+ P ++ +L Sbjct: 186 GDRVVLEANDAYW-GPKPTASKITYQIVAEPATRVAGLISGEYDIITTLTPDDI--QLIN 242 Query: 285 EIPDEVHVDPYLCTYY-YEINNQKPPFNDVRVRTALKLGMDRDIIVNKV-KAQGNMPAYG 342 PD + ++ + N + F D ++R AL L ++R I+V + K Q ++PA Sbjct: 243 SYPDLETRGTLIENFHMFTFNMNQEVFKDKKLRRALALAVNRPIMVEALWKKQASIPAGF 302 Query: 343 YTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAI 402 P Y + + + E EEAK+L+ E+GY P+T + + N + Sbjct: 303 NFPNYGETFDPKRK-----AMEYNVEEAKRLVKESGYDG-TPITYHTMGNYYANAMPALM 356 Query: 403 AASSLWKKNIGVNVKL 418 +WK+ IGVNV + Sbjct: 357 MMIEMWKQ-IGVNVVM 371 >5ZA4-A nrPDB Length = 488 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 91/347 (26%), Positives = 150/347 (43%), Gaps = 46/347 (13%) Query: 52 LDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPG------VAESWDNKDAKVWTFHLRKD 105 DP G + +FEGL+ D HP A+ + KD + LR+ Sbjct: 22 FDPLTSSGASSMAANLHIFEGLV----DLHPVTRQPYLALAAKEPEQKDDLTYYISLREG 77 Query: 106 AKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAI 165 A + DG+PVT +D VYS++R +DP AS +A ++ + IA V A+ Sbjct: 78 AMFHDGSPVTTEDVVYSFERVLDPAKASLFAQFIPF--IA---------------SVTAL 120 Query: 166 DDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVN 225 DD+ +E L P F + L VPK +E + + +G Y + Sbjct: 121 DDNVVEFKLKYPFALFKERLT--IIKIVPKHIVEAGQSAFD--AKPIGSGPYKFVSATKD 176 Query: 226 ERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKE 285 +RIV E + Y + + ++T+ ++ + V SG + S+P ++LK++ Sbjct: 177 DRIVFEANTVYNGHYPAKVEKMTWFLLSDDAARVTAQESGRVQAI-ESVPYLDAERLKRK 235 Query: 286 IPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTP 345 + V + N +K PF++ +VR AL +D+ +++ V A Y Sbjct: 236 --NNVESVQSFGLLFLMFNCEKAPFDNPKVRQALHYALDKQKLIDIVFLGNAKAATSYL- 292 Query: 346 PYTDGAKLTQPEWFGWSQEKRNEEAK--KLLAEAGYTADKPLTINLL 390 + T P++ S + ++AK KLLAEAG T LT LL Sbjct: 293 ------QDTHPDYVKASSQYDYDKAKAEKLLAEAGITN---LTFQLL 330 >4OER-A nrPDB Length = 500 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 120/504 (23%), Positives = 216/504 (42%), Gaps = 60/504 (11%) Query: 49 VQSLDPHKIEGVPESNISRDL-FEGLLVSDLDGHPAPGVAESWD-NKDAKVWTFHLRKDA 106 V L+PH P ++++ +E L+ + DG P +AESW+ ++D + +TF LR+D Sbjct: 12 VGPLNPHLYS--PNQMFAQNMVYEPLVHYNADGTVGPWLAESWEASQDGRSYTFKLREDV 69 Query: 107 KWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAID 166 K+S+G A +V N + + ++ + +++++ + + Sbjct: 70 KFSNGEVFDAA--------AVKANIDTVLQNRPRHNWLELVNQMVSA---------EVVG 112 Query: 167 DHTLEVTLSEPVPYFYKLLVHPST-SPVPKAAIEKFGEKWTQPGNI--VTNGAYTLKDWV 223 + + + L +P +Y LL S P A +F T G + + G + L + Sbjct: 113 PYKVRINLKKP---YYPLLQELSLPRPFRFIAPSQFKNGGTADGIVAPIGTGPWKLTETK 169 Query: 224 VNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM---TNNSMPIELFQ 280 + E V R+ +YW K Q+T I T + +GEID+ T + + F+ Sbjct: 170 LGEHDVFTRNDSYW-GPKPAYEQITVKVIPDPNTRAIAFEAGEIDLIYGTEGPISPDTFE 228 Query: 281 KLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPA 340 + +K + L T +N D+ VR A+ +D+D ++ V A Sbjct: 229 RFQKMGIYNTELSEPLETRVLALNTNHGATKDLAVRKAINHAVDKDTMIATVLYGTQKRA 288 Query: 341 ---YGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTAD----------KPLTI 387 + PY + +P F + A +LL EAG+TA +PL I Sbjct: 289 DTLFADNVPYANIG--LKPYAFDPAL------AARLLDEAGWTAKASGDIREKDGQPLAI 340 Query: 388 NLLYNTSD-LHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD-VARAGWCAD 445 L + +D + K +A + +K +G++VKL +E + + G FD + W A Sbjct: 341 ELCFIGTDAISKSMAEIVQADLRK-VGIDVKLTGEEESSIYARQRDGRFDMIFNQTWGAP 399 Query: 446 YNEPTSFLNTMLSNSSMN-TAHYKSP---AFDSIMAETLKVTDEAQRTALYTKAEQQLDK 501 Y +P +F+++M S + A P D+ + + L TDE R ALY +L + Sbjct: 400 Y-DPHAFVSSMRVPSHADYQAQLGLPDKAKIDAEIGQVLVSTDETARQALYKDILTRLHE 458 Query: 502 DSAIVPVYYYVNARLVKPWVGGYT 525 ++ +P+ + KP VG T Sbjct: 459 EAVYLPLTSVTAMAVAKPEVGKIT 482 >5IPW-A nrPDB Length = 633 Score = 88.2 bits (217), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 113/420 (26%), Positives = 165/420 (39%), Gaps = 86/420 (20%) Query: 80 GHPAPGVAESWDN-KDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASY 138 G PG+A+SW+ ++ +V+ FHLRK KWSDG P TA D V+ W Sbjct: 92 GKLVPGLAKSWEVLENGRVYIFHLRKGVKWSDGAPYTAHDIVF-WVND------------ 138 Query: 139 LQYGHIAGIDEILEGKKPITDLGVK--AIDDHTLEVTLSEP-------VPY--------F 181 I G D+I K ++GVK A+DD+T++ S+P VPY Sbjct: 139 -----IVGNDDITPSKPDWYNIGVKVEALDDYTVKFEFSKPYGLFLLKVPYGGFTGAPAH 193 Query: 182 YKLLVHPSTSP---VPKAAIEKFGEKWTQPGN-----IVTNGAYTLKDWV-----VNERI 228 Y HP +P + K +E W N + TL W + Sbjct: 194 YLKQFHPKYTPMEEIEKKMVEGVHNTWVDLFNDKNDFLENTELPTLSPWKPITDPTEQFY 253 Query: 229 VLERSPTYW-----NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMT------------N 271 +LER+P +W N I+ V + + ++ + + SGEIDM N Sbjct: 254 ILERNPYFWAVDIEGNQLPYIDYVRHEYVKNDEVILLKAISGEIDMQWRHIGGLGAGAGN 313 Query: 272 NSMPIELFQ----KLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDI 327 ++ +E Q ++ K I Y + + FNDVR R AL L ++R+ Sbjct: 314 FTLLMENSQSGGYRVLKWIAANGSASRISLNYAHSDEVLRKVFNDVRFRQALSLAINREE 373 Query: 328 IVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTAD----- 382 I N++ G A G+ PEW E + A KLL E G D Sbjct: 374 I-NEILFNG--LAEPRQASLVSGSPYFDPEWEKAYAEYDPDRANKLLDEMGLKWDDKHEY 430 Query: 383 ------KPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD 436 +PL + T H + WK+ IGV V++ N E F + G FD Sbjct: 431 RLLPDGRPLRFTITV-TGQFHVDVWTMVKEYWKQ-IGVWVEIENLERSLFYERADAGDFD 488 >2WOP-A nrPDB Length = 562 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 113/484 (23%), Positives = 203/484 (41%), Gaps = 69/484 (14%) Query: 82 PAPGVAESWD--NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYL 139 PAP +AE + + WT+ LR+ ++ DGTP+T+ D ++ QR + +YL Sbjct: 81 PAPDLAEGPGEVSDGGRTWTYRLRRGLRYDDGTPITSDDVRHAVQRVFAQDVLPGGPTYL 140 Query: 140 QYGHIAGIDEILEGKKPI-----TDLGVKAI---DDHTLEVTLSEPVPYFYKLLVHPSTS 191 I + + ++P TD ++++ D+HT+ L+ P F L+ P + Sbjct: 141 -------IPLLDDPERPYPGPYRTDEPLRSVLTPDEHTIVFRLTRPFSDFDHLMAQPCAA 193 Query: 192 PVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLP 251 PVP+ + G + + + ++G Y + + + LER+P +W+ A I LP Sbjct: 194 PVPRRS--DTGADYGR--DPRSSGPYRVARHEPDTLLHLERNP-HWDRATDPIRPA--LP 246 Query: 252 IASEVT---DVN----RYRSGEIDMTNNSMPIELFQKLKKEIPDEV---HVDPYLCTYYY 301 E+T DV+ R +GE D+ ++ + ++ DEV H D ++ + Sbjct: 247 DRVELTIGLDVDVLDARLIAGEFDINLEGRGLQHAAQ-RRATADEVLRSHTDNPRTSFLH 305 Query: 302 EINNQK--PPFNDVRVRTALKLGMDRDIIVNKVKA----QGNMPAYGYTPPYTDGAKL-- 353 + Q PPF++V VR A++ D+ I++ + G++ + P L Sbjct: 306 FVAMQPHIPPFDNVHVRRAVQYAADK-ILLQDARGGPVNGGDLTTALFPPTLPAHQDLDL 364 Query: 354 --TQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIAA--SSLWK 409 T P+ G R E A L + G+ A + T +L A SL + Sbjct: 365 YPTGPDLRGDLDAARAELAAAGLPD-GFRA--------VIGTQRGKFRLVADAVVESLAR 415 Query: 410 KNIGVNVKLVNQEWKTFLDTRHQGTFDVARAG-----WCADYNEPTSFLNTMLSNSSM-- 462 I + VK ++ L H T G W AD+ FL ++ + Sbjct: 416 VGIELTVKELDVATYFSLGAGHPETVREHGLGLLVTDWGADFPTEYGFLAPLVDGRQIKR 475 Query: 463 -----NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLV 517 N P ++++ ETL TD A R L+ E+++ + + ++P+ + Sbjct: 476 NGGNWNLPELDDPEVNALIDETLHTTDPAARAELWRAVERRVMEHAVLLPLVHDKTLHFR 535 Query: 518 KPWV 521 PWV Sbjct: 536 NPWV 539 >3T66-A nrPDB Length = 496 Score = 75.5 bits (184), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 120/477 (25%), Positives = 191/477 (40%), Gaps = 80/477 (16%) Query: 51 SLDPH-KIEGVP-ESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKW 108 SLDPH + +P + I+ L + V + + AP +AESWD+ D + WT LR+D + Sbjct: 25 SLDPHVDMTYIPVRAGITETL---VRVDEENVTIAPWLAESWDSTDGQHWTIKLREDVTF 81 Query: 109 SDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDH 168 +G + A+ S +R++D + A A IDEI D + Sbjct: 82 QNGKEMDAEAVKASLERALDESVAIENA--------LKIDEI-------------EADGY 120 Query: 169 TLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERI 228 TL +T EP P F LV+P+ S I+ E +T + V G + L+ + ++ Sbjct: 121 TLHITTKEPFPEFISELVNPNVS-----IIDVTEEDFT--NHPVGTGPFALESFTPGSKL 173 Query: 229 VLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPD 288 L R YW+ A ++ VT+ SG+ D+ +E + L+ Sbjct: 174 ELVRYDEYWDGASK-LDSVTFSFNEDASARSLALESGQADIVYRP-EVESIETLQANEGI 231 Query: 289 EVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYT 348 V T+ +N + DV VR A+ + +DR IV+ + GY Sbjct: 232 MVEATETFRTHNLTMNLDRDSLKDVNVRRAVDVLLDRQEIVDTI-------MLGYA-EVA 283 Query: 349 DGAKL-TQPEWFGWSQEKRN---EEAKKLLAEAGYTAD--------KPLTINLLYNTSDL 396 DG + T P F S EK+ + A + L EAGYT + +PL +L S Sbjct: 284 DGPFIPTLP--FAPSYEKKETGTDIAIQYLEEAGYTLENGQMQKDGEPLHFTVLTYGSRA 341 Query: 397 HKKLAIAASSLWKKNIGVNVKL-----------VNQEWKTFLDTRHQGTFDVARAGWCAD 445 L K IG+ V++ N++W L T T AG+ Sbjct: 342 ELPLIAQVFQSNAKQIGIEVEIRQIEVPEEYMASNRDWD--LITYSNVTSPRGDAGY--- 396 Query: 446 YNEPTSFLN-TMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDK 501 +LN T ++N + P I+ E + D+ R L +A +D+ Sbjct: 397 ------YLNATYHPTGALNFSSVNDPELTGIIDELNRTVDQDVRAKLTEQAAAYIDE 447 >3I5O-A nrPDB Length = 592 Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 123/513 (23%), Positives = 205/513 (39%), Gaps = 95/513 (18%) Query: 61 PESNISRDLFEGLLVSDLD-GHPA--PGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQ 117 P+S D F L D G A P +AE ++ D K ++R +A+WSDG P+TA Sbjct: 29 PQSTWGTDQFMYLPAFQYDLGRDAWIPVIAERYEFVDDKTLRIYIRPEARWSDGVPITAD 88 Query: 118 DFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEP 177 DFVY+ + + + L G G D +E VKA+D +E E Sbjct: 89 DFVYALELTKE----------LGIGPGGGWDTYIE--------YVKAVDTKVVEFKAKEE 130 Query: 178 -VPYFYKLLVHPSTSPVPKAAIEKFGEK-----WT--QPGNIVTNGAYTLKDWVVNERIV 229 + YF L P+PK E+ + W +P V +G Y L + N +V Sbjct: 131 NLNYFQFLSYSLGAQPMPKHVYERIRAQMNIKDWINDKPEEQVVSGPYKLYYYDPN-IVV 189 Query: 230 LERSPTYWNNAKTVINQVTYL--------PIASEVTDVNRYRSGEIDMTNNSMP--IELF 279 +R +W + + YL P AS + G+ID +P EL+ Sbjct: 190 YQRVDDWWGKDIFGLPRPKYLAHVIYKDNPSASLA-----FERGDIDWNGLFIPSVWELW 244 Query: 280 QKLKKEIPDEVHVDPYLC---TYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKV---- 332 +K + +PY + +NN KP +D VR A+ + + ++ K Sbjct: 245 EKKGLPVGTWYKKEPYFIPDGVGFVYVNNTKPGLSDPAVRKAIAYAIPYNEMLKKAYFGY 304 Query: 333 --KAQGNMPAYGYTP--PYTDG--AKLTQPEWFGWSQEKRN----EEAKKLLAEAGY--- 379 +A +M + P Y D AK T FG +++ R + A K+L EAGY Sbjct: 305 GSQAHPSMVIDLFEPYKQYIDYELAKKT----FG-TEDGRIPFDLDMANKILDEAGYKKG 359 Query: 380 ----------TADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDT 429 T P TI++ Y +D + A +L ++IG++VK ++ + D Sbjct: 360 PDGVRVGPDGTKLGPYTISVPYGWTDWMMMCEMIAKNL--RSIGIDVKTEFPDFSVWADR 417 Query: 430 RHQGTFDVARAGWCA--DYNEPTSFLNTMLSNS----------SMNTAHYKSPAFDSIMA 477 +GTFD+ W ++ P + +L + + Y + ++ Sbjct: 418 MTKGTFDLI-ISWSVGPSFDHPFNIYRFVLDKRLSKPVGEVTWAGDWERYDNDEVVELLD 476 Query: 478 ETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYY 510 + + D R Y + +Q + +D +P +Y Sbjct: 477 KAVSTLDPEVRKQAYFRIQQIIYRDMPSIPAFY 509 >5YQW-A nrPDB Length = 532 Score = 71.2 bits (173), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 116/505 (22%), Positives = 208/505 (41%), Gaps = 90/505 (17%) Query: 69 LFEGLLV-SDLDGH-PAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQR 125 ++E L+V +++ G+ P +AE++ + D TF +RK KWSDG TA D VYS+ Sbjct: 36 IYEPLVVFNEMHGNTPVFRLAENFQMSDDLMSVTFDIRKGVKWSDGEAFTADDVVYSF-- 93 Query: 126 SVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEP---VPY-F 181 N Q +GI+ + GV+ ++D+ ++ LSE VPY Sbjct: 94 ----NLVKEKPELDQ----SGINSWV--------TGVEKVNDYQVKFRLSEANSNVPYEI 137 Query: 182 YKLLVHPSTSPVPKAAIEKFGEKWTQPG-NIVTNGAYTLKDWVVNERIVLERSPTYWNNA 240 K+ V VPK K + T N V +G +T+ D + + +P YW+ A Sbjct: 138 AKVPV------VPKHVWSKVKDPSTFTNENPVGSGPFTVIDTFTPQLYIQCENPNYWDAA 191 Query: 241 KTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYY 300 ++ + IA+ + + +GE+D T++ +P ++ + P + P T Sbjct: 192 NLDVDCLRVPQIANNDQFLGKVVNGEMDWTSSFVP-DIDRTYAAASPKHHYWYPPAGTQA 250 Query: 301 YEINNQKP------PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLT 354 + +N + P +V R A + +DR I++ G G + G Sbjct: 251 FVVNFKNPDAAKNEALTNVDFRRAFSMALDRQTIIDIAFYGG-----GTVNDFASGLGYA 305 Query: 355 QPEWFGWSQEKRN-----------EEAKKLLAEAGYT-------ADKPL--TINLLYNT- 393 + WS EK + E AKKLLA+AG+ D P + LL + Sbjct: 306 ---FEAWSDEKTHDKFKAYNSYNAEGAKKLLAKAGFKDVNKDGFVDTPSGKSFELLIQSP 362 Query: 394 ---SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT 450 +D + + +A L +G+ + ++ + +GT+DVA + +P Sbjct: 363 NGWTDFNNTVQLAVEQL--AEVGIKARARTPDFSVYNQAMLEGTYDVAYTNYFHG-ADPY 419 Query: 451 SFLNTMLSNSSMNTA---------HYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDK 501 ++ N+ NS++ + YK+ D ++ K D+ ++ + +Q + + Sbjct: 420 TYWNSAY-NSALQSGDGMPRFAMHFYKNEKLDGLLNSFYKTADKQEQLEIAHGIQQIIAQ 478 Query: 502 DSAIVPV------YYYVNARLVKPW 520 D +PV Y Y R W Sbjct: 479 DQVTIPVLSGAYMYQYNTTRFTGWW 503 >6EQ0-A nrPDB Length = 683 Score = 68.9 bits (167), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 104/252 (41%), Gaps = 41/252 (16%) Query: 79 DGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRS-VDPNTASPYA 136 D P P +A+SW+ ++D T HL K AKWSDG A D ++ W+ + VDPN + Sbjct: 134 DTEPLPNLAKSWEWSEDGHTLTMHLVKGAKWSDGEAFNADDVMFYWEDAVVDPNVSP--- 190 Query: 137 SYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVP--YFYKLLVHPSTSPVP 194 G A + EG +K IDD+T+E T P Y Y + +PS P P Sbjct: 191 ----LGGGASPEAFGEGTT------LKKIDDYTVEWTFKAAFPKQYLYT-MAYPSFCPGP 239 Query: 195 KAAIEKFGEKWTQPG-------------NIVTNGAYTLKDWVVNERIVLERSPTYW---- 237 ++ K+++ N+ GA+ + ++ IVL R+P YW Sbjct: 240 SHILKPQHPKYSKNTYNQFKNAFPPEYMNMPVMGAWVPVSYRPDDLIVLRRNPYYWKVDE 299 Query: 238 -NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKK----EIPDEVHV 292 +N+V Y DV +G D +N P LK+ P + Sbjct: 300 KGQQLPYLNEVHYKLSTWADRDVQAV-AGSGDFSNLEQPENFVASLKRAADPNAPARLAF 358 Query: 293 DPYLCTYYYEIN 304 P L Y ++N Sbjct: 359 GPRLIGYNLQMN 370 >1XOC-A nrPDB Length = 520 Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 101/469 (21%), Positives = 190/469 (40%), Gaps = 47/469 (10%) Query: 63 SNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKV-WTFHLRKDAKWSDGTPVTAQDFVY 121 ++I L+ L +D + +AES D + + ++K K+ DG +TA D V+ Sbjct: 46 TDIENMLYSFLTKTDEKLNVKLSLAESIKELDGGLAYDVKIKKGVKFHDGKELTADDVVF 105 Query: 122 SWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYF 181 ++ + + G E+L+ V+ D+ + L F Sbjct: 106 TYSVPLSKDYK---------GERGSTYEMLKS--------VEKKGDYEVLFKLKYKDGNF 148 Query: 182 YKLLVHPSTSPVPK-----AAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTY 236 Y + ST+ +PK I E + +G + K+W + I LE + Y Sbjct: 149 YNNALD-STAILPKHILGNVPIADLEENEFNRKKPIGSGPFKFKEWKQGQYIKLEANDDY 207 Query: 237 WNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYL 296 + + ++ VTY I + ++G+I+ N +P ++ +K ++ D L Sbjct: 208 FE-GRPYLDTVTYKVIPDANAAEAQLQAGDINFFN--VPATDYKTAEKFNNLKIVTDLAL 264 Query: 297 CTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKV-KAQGNMPAYGYTPPYTDGAKLTQ 355 Y N + F D +VR AL +DR+ IV++V G + +P + K Sbjct: 265 SYVYIGWNEKNELFKDKKVRQALTTALDRESIVSQVLDGDGEVAYIPESPLSWNYPKDID 324 Query: 356 PEWFGWSQEKRNEEAKKLLAEAGYTA----------DKPLTINLLYNTSD-LHKKLAIAA 404 F ++++K AK++LAEAG+ K + L N + + + +A+ Sbjct: 325 VPKFEYNEKK----AKQMLAEAGWKDTNGDGILDKDGKKFSFTLKTNQGNKVREDIAVVV 380 Query: 405 SSLWKKNIGVNVKLVNQEWKTFLDTRH--QGTFDVARAGWC-ADYNEPTSFLNTMLSNSS 461 KK IG+ VK EW ++ + FD GW + + + ++ Sbjct: 381 QEQLKK-IGIEVKTQIVEWSALVEQMNPPNWDFDAMVMGWSLSTFPDQYDIFHSSQIKKG 439 Query: 462 MNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYY 510 +N YK+ D +M + ++D Q + Y + Q++ +D +YY Sbjct: 440 LNYVWYKNAEADKLMKDAKSISDRKQYSKEYEQIYQKIAEDQPYTFLYY 488 >4PFT-A nrPDB Length = 544 Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 115/485 (23%), Positives = 197/485 (40%), Gaps = 73/485 (15%) Query: 69 LFEGLLVSD-LDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQ--R 125 ++E L + D L+ P +AE + + LRK +W DG P+TA D V++++ + Sbjct: 38 VYEPLFLYDPLNDKFEPWLAEKGEWVSNNEYVLTLRKGLRWQDGVPLTADDVVFTFEIAK 97 Query: 126 SVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLL 185 + SP ++L G I +DE TL+ S+P +K + Sbjct: 98 KYTGISYSPVWNWL--GRIERVDE------------------RTLKFVFSDPRYQEWKQM 137 Query: 186 VHPSTSPVPKAAIE-KFGEKWTQPG--NIVTNGAYTLKDWVVNERIVLERSPTYWNNAKT 242 + +T VPK E K E+ Q N V +G Y ++ W ++R V +++ +W + Sbjct: 138 LI-NTPIVPKHIWENKTEEEVLQAANENPVGSGPYYVESW-ADDRCVFKKNGNWWGIREL 195 Query: 243 VIN----QVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLC- 297 + ++ L + S V GE+D +N +P K I PY+ Sbjct: 196 GYDPKPERIVELRVLSNNVAVGMLMKGELDWSNFFLPGVPVLKKAYGIVTWYENAPYMLP 255 Query: 298 --TYYYEINNQKPPFNDVRVRTALKLGMDRDIIV-----NKVKA---QGNMPAYGYTPPY 347 T IN K P + R A+ ++ + IV N V A G +P GY Y Sbjct: 256 ANTAGIYINVNKYPLSIPEFRRAMAYAINPEKIVTRAYENMVTAANPAGILPLPGYMKYY 315 Query: 348 TDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYT-----------ADKP--LTINLLYNTS 394 +G+ + E AKK+L E G+ KP LTI Y + Sbjct: 316 PKEVVDK----YGFKYDP--EMAKKILDELGFKDVNKDGFREDPNGKPFKLTIECPYGWT 369 Query: 395 DLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT-SFL 453 D + A L K +G+NV+ ++ + D + G FD+ + + S+ Sbjct: 370 DWMVSIQSIAEDLVK--VGINVEPKYPDYSKYADDLYGGKFDLILNNFTTGVSATIWSYF 427 Query: 454 NTML--------SNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAI 505 N + + S N Y +P ++++ E + D+A+ + K + L KD Sbjct: 428 NGVFYPDAVESEYSYSGNFGKYANPEVETLLDELNRSNDDAKIKEVVAKLSEILLKDLPF 487 Query: 506 VPVYY 510 +P++Y Sbjct: 488 IPLWY 492 >1ZTY-A nrPDB Length = 529 Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 108/505 (21%), Positives = 206/505 (40%), Gaps = 90/505 (17%) Query: 69 LFEGLLV-SDLDGH-PAPGVAESWDNKDAKV-WTFHLRKDAKWSDGTPVTAQDFVYSWQR 125 ++E L+V +++ G+ P +AES+ D + TF +RK KWSDG TA D VYS Sbjct: 33 IYEPLVVFNEMKGNTPVFRLAESYKMADDLMSVTFDIRKGVKWSDGEAFTADDVVYS--- 89 Query: 126 SVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEP---VPYFY 182 +G + E+ + V+ +D++ + LSE VPY Sbjct: 90 ---------------FGLLKAKPELDQRGINKWVTSVEKVDEYKVRFRLSEANSNVPYEI 134 Query: 183 KLLVHPSTSPVPKAAIEKFGEKWTQ--PGNIVTNGAYTLKDWVVNERIVLERSPTYWNNA 240 L+ P+ + K + T N V G +T+ D + + R+P YW+ A Sbjct: 135 SLI------PIVAEHVWKDVKDPTTFTNENPVGTGPFTVIDTFTPQLYIQCRNPNYWDAA 188 Query: 241 KTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYY 300 ++ + IA+ + + + E+D T++ +P ++ + P+ + P T Sbjct: 189 NLEVDCLRVPQIANNDQLLGKIVNSELDWTSSFVP-DIDRTYAAANPNHHYWYPAAGTQA 247 Query: 301 YEINNQKP------PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLT 354 + +N + P ++V R A + +DR I+ ++ YG + D A Sbjct: 248 FMVNFKNPDPAKKEALDNVDFRRAFSMALDRQTII-------DIAFYG-SGTVNDFASGL 299 Query: 355 QPEWFGWSQEKRN-----------EEAKKLLAEAGYT-------ADKPL--TINLLYNT- 393 + WS E + E +KKLLA+AG+ + P + LL + Sbjct: 300 GYAFEAWSDEATHKKYKGFNTYDVEGSKKLLAKAGFKDVNGDGFVETPSGKSFELLIQSP 359 Query: 394 ---SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT 450 +D + + +A L + +G+ K E+ + +GT+DVA + +P Sbjct: 360 NGWTDFNNTVQLAVEQL--QEVGIKAKARTPEFAVYNQAMLEGTYDVAYTNYFHG-ADPF 416 Query: 451 SFLNTMLSNSSMNTA---------HYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDK 501 ++ N+ NS++ + ++ D ++ K D+ ++ A+ ++ + + Sbjct: 417 TYWNSGY-NSALQSGDGMPRFAMHYFTDKKLDGLLDSFYKTADKNEQLAIAHGIQKIIAE 475 Query: 502 DSAIVPV------YYYVNARLVKPW 520 + +PV Y Y R W Sbjct: 476 NQVTIPVMSGAWMYQYNTTRFTGWW 500 >3DRH-A nrPDB Length = 590 Score = 62.4 bits (150), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 115/491 (23%), Positives = 204/491 (41%), Gaps = 69/491 (14%) Query: 85 GVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHI 144 G A+ +K++K T LRKD KWSDG+ VTA+D+ ++++ +P S + +I Sbjct: 85 GAADVALDKESKTATITLRKDLKWSDGSEVTAKDYEFTYETIANPAYGSDRWT-DSLANI 143 Query: 145 AGIDEILEGK-KPITDLGV-KAIDDHTLEVTLSEPVP--------YFYKLLV-HPSTSPV 193 G+ + GK K I+ + + ++V E P YF + + + V Sbjct: 144 VGLSDYHTGKAKTISGITFPDGENGKVIKVQFKEMKPGMTQSGNGYFLETVAPYQYLKDV 203 Query: 194 PKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIA 253 + + T+P + G + ++ V E I +P YW K +N +TY + Sbjct: 204 APKDLASSPKTTTKP---LVTGPFKPENVVAGESIKYVPNPYYWGE-KPKLNSITY-EVV 258 Query: 254 SEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEV--HVDPYLCTYYY---------- 301 S V S + D+ N M ++++K +V Y+ YY Sbjct: 259 STAKSVAALSSSKYDII-NGMVSSQYKQVKNLKGYKVLGQQAMYISLMYYNLGHYDAKNS 317 Query: 302 -EINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFG 360 + ++K P D VR A+ + + NK + PA PP + T G Sbjct: 318 INVQDRKTPLQDQNVRQAIGYARNVAEVDNKFSNGLSTPANSLIPPIF--KQFTSSSVKG 375 Query: 361 WSQEKRNEEAKKLLAEAGYTADKPL--------TINLLY--NTSDLHKK-LAIAASSLWK 409 + ++ ++A KLL E G+ +K ++L+Y D + + +A WK Sbjct: 376 YEKQDL-DKANKLLDEDGWKLNKSTGYREKDGKELSLVYAARVGDANAETIAQNYIQQWK 434 Query: 410 KNIGVNVKLVN---QEWKTFLDTRHQGT------FDVARAGWCADYNEPTSFLNTMLSNS 460 K IGV V L N E+ +++D H T +D+ W +EP+ + + + Sbjct: 435 K-IGVKVSLYNGKLMEFNSWVD--HMTTPPGANDWDITDGSWSL-ASEPSQ-QDLFSAAA 489 Query: 461 SMNTAHYKSPAFDSIMAETLKVTDEAQ------RTALYTKAEQQLDKDSAIVPVYYYVNA 514 N H+ DS + + L D A+ R A + K ++ ++K + ++P + +N Sbjct: 490 PYNFGHFN----DSEITKDLNDIDSAKSENPTYRKAAFVKYQEDMNKKAYVIPTNFMLNY 545 Query: 515 RLVKPWVGGYT 525 V V G T Sbjct: 546 TPVNKRVVGMT 556 >4OFL-A nrPDB Length = 499 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 91/435 (20%), Positives = 172/435 (39%), Gaps = 72/435 (16%) Query: 94 DAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEG 153 D K W L+ D K+SDG+P+TA+D +++ N A+ + G+ Sbjct: 57 DGKTWLLTLKPDLKFSDGSPLTAKDVAFTY------NNAAASGGKVDMGNF--------- 101 Query: 154 KKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVT 213 L + ID + + L P F +L K + + +K + Sbjct: 102 ------LSAEVIDPLNVRIHLKAPQSTFVNVLGSLGIVSADKYNAKTYAQK------PIG 149 Query: 214 NGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTN-- 271 G Y L + +++++E +P Y N K +++ ++ E + +SG++ + Sbjct: 150 AGPYRLVSFQPGQQMIVEANPYYAGN-KNDFDKLIFV-FLDEDSAFAAAQSGQLGVVRIP 207 Query: 272 NSMPIELFQKLKKEIPDEVHVDPYLC---------TYYYEINNQKPPFNDVRVRTALKLG 322 SM + +K + V + + Y I N DV +R A+ Sbjct: 208 PSMAVGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTA--DVAIRRAINYA 265 Query: 323 MDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTAD 382 ++R ++ +++ +PAY G P+ ++ ++AK++L +AG+ + Sbjct: 266 INRQLLADQIMEGHAIPAY----TGVQGLPWNNPD--SAIKDGDIDKAKQILEQAGWQLN 319 Query: 383 K---------PLTINLLYNTSDLHKK-LAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQ 432 P I L Y + D ++ LA A S+ K IG++V L + W+T H Sbjct: 320 SQGTREKNGLPAKITLWYTSGDTTRRDLAQALRSMLKP-IGIDVDLKSGSWETVERNMHA 378 Query: 433 GTFDVARAGWCADYNEPTSFLNTMLSNSS----MNTAHYKSPAFDSIMAETLKVTDEAQR 488 + GW + +P + SN++ N +YK+P D + + L Q Sbjct: 379 ---NPTLFGWGS--LDPMELYHHYSSNAAGVEYYNPGYYKNPMVDKHLQQALDAPTWQQA 433 Query: 489 TALYTKAEQQLDKDS 503 + QQ+D D Sbjct: 434 VPFW----QQVDWDG 444 >4ONY-A nrPDB Length = 595 Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 61/241 (25%), Positives = 99/241 (41%), Gaps = 37/241 (15%) Query: 100 FHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITD 159 F L AKWSDG PVT D ++++ + PY S + +A I++ E Sbjct: 117 FTLNPKAKWSDGQPVTVDDVLFTYDILTE-KGRPPYNSRMS--RVAKIEKTGE------- 166 Query: 160 LGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEK--FGEKWTQPGNIVTNGAY 217 ++ T +E + +L+ S +PK AI + FG +P + +G Y Sbjct: 167 --------RSVRFTFNEKSDREFPMLIAGSMPVLPKHAINRDTFGNSTLEPP--IGSGPY 216 Query: 218 TLKDWVVNERIVLERSPTYWNN---AKTVINQVTYLPIA---SEVTDVNRYRSGEIDMTN 271 + +RIV +R+P YW ++ N + I +E + ++ G +D+ Sbjct: 217 VVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNETSLFESFKKGILDIFI 276 Query: 272 NSMPIELFQKL--------KKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGM 323 PI ++KL K I D + N ++P F D RVR AL L Sbjct: 277 EGNPIR-WEKLYDFPAVEQGKVIKDTFEKGTPADMLGFVFNTRRPIFADRRVRQALGLLF 335 Query: 324 D 324 D Sbjct: 336 D 336 >4PFU-A nrPDB Length = 547 Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 107/488 (21%), Positives = 201/488 (41%), Gaps = 77/488 (15%) Query: 69 LFEGLLVSD-LDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSV 127 ++E + D L G+ P +AE + D+K + LR+ W D P+T++D ++++ Sbjct: 38 VYETMFFYDPLTGNFDPWLAEKGEWLDSKTYRVVLREGIYWHDNVPLTSEDVRFTFE--- 94 Query: 128 DPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVH 187 A Y H + + E L+ ++ D+ T+ +P + + L++ Sbjct: 95 ---IAKKYKGI----HYSSVWEWLD--------HIETPDNRTVIFVFKDPRYHEWNELLY 139 Query: 188 PSTSPVPKAAIEKFGE-KWTQPGN--IVTNGAYTLKDWVVNERIVLERSPTYWN----NA 240 + VPK E+ E Q N + +G Y W N +++ ER +W Sbjct: 140 -TLPIVPKHIWEEKDETTILQSSNEYPLGSGPYVAHSWDQN-KMIFERFENWWGTKVMGV 197 Query: 241 KTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMP-IELFQKLKK------EIPDEVHVD 293 K V + + S + GE+D +N +P + + +K+ E P H+ Sbjct: 198 KPAPKYVVIVRVLSNNVALGMLMKGELDFSNFMLPGVPILKKVYNLNTWYDEPP--YHLS 255 Query: 294 PYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPA--YGYTPPYTDGA 351 + + +N +K P + R A+ + ++ D IV +V + A G+ P + Sbjct: 256 STVVGLF--LNARKYPLSLPEFRRAIAMSINADPIVQRVYEGAVLKADPLGFLPN-SVWM 312 Query: 352 KLTQPEWFGWSQEKRN-----EEAKKLLAEAGY----------TAD-KP--LTINLLYNT 393 K E EK EEAK +L + G+ T D KP LTI Y Sbjct: 313 KYYPKE----VVEKHGFKYDPEEAKSILDKLGFRDVNGDGFRETPDGKPIKLTIECPYGW 368 Query: 394 SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDV-ARAGWCADYNEPTSF 452 +D + + + L K +G+N + + + + ++G FD+ A + P ++ Sbjct: 369 TDWMQAIQVIVDQL--KVVGINAEPYFPDSSKYYENMYKGEFDIEMNANGTGISSTPWTY 426 Query: 453 LNTMLSNSSM--------NTAHYKSPAFDSIMAETLKV-TDEAQR-TALYTKAEQQLDKD 502 NT+ ++ N Y++P +S++ E + D ++ T L K + L KD Sbjct: 427 FNTIFYPDALESEFSYTGNYGRYQNPEVESLLEELNRTPLDNVEKVTELCGKLGEILLKD 486 Query: 503 SAIVPVYY 510 +P++Y Sbjct: 487 LPFIPLWY 494 >5YH8-A nrPDB Length = 510 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 111/518 (21%), Positives = 200/518 (38%), Gaps = 92/518 (17%) Query: 37 EKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDA 95 E + L ++ ++PH + G S S ++E L+ + DG P +A+ WD ++D Sbjct: 10 ENKQLTYTTVKDIGDMNPH-VYGGSMSAESM-IYEPLVRNTKDG-IKPLLAKKWDVSEDG 66 Query: 96 KVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKK 155 K +TFHLR D K+ DGTP A +V N ID + E KK Sbjct: 67 KTYTFHLRDDVKFHDGTPFDAD--------AVKKN----------------IDAVQENKK 102 Query: 156 -----PITDL--GVKAIDDHTLEVTLSE-----------PVPYFYKLLVHPS--TSPVPK 195 I+ L VK D +T+E+ L E P PY + V P + K Sbjct: 103 LHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVF---VSPKDFKNGTTK 159 Query: 196 AAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASE 255 ++KF G + L + +E ++ YW K+ +N+V + + Sbjct: 160 DGVKKFD----------GTGPFKLGEHKKDESADFNKNDQYWGE-KSKLNKVQAKVMPAG 208 Query: 256 VTDVNRYRSGEI------DMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP- 308 T + GE D +S+ + ++LK +V + T +N+ K Sbjct: 209 ETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKD 268 Query: 309 -PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRN 367 +D VR A+ ++RD I ++ PA P +++ Sbjct: 269 NAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMP-----TRKYDL 323 Query: 368 EEAKKLLAEAGYTADKP----------LTINLLYNTSDLHKKLAIAASSLWKKNIGVNVK 417 ++A+ LL EAG+ K L + + Y+ +K K +G+ + Sbjct: 324 KKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLN 383 Query: 418 LVNQEWKTFLDTRHQGTFDVA-RAGWCADYNEPTSFLNTMLSNSSMNTA----HYKSPAF 472 + + + R G +D+ W Y +P S + + + +A K + Sbjct: 384 INGETSDKIAERRTSGDYDLMFNQTWGLLY-DPQSTIAAFKAKNGYESATSGIENKDKIY 442 Query: 473 DSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYY 510 +SI + K+ + +R+ Y +Q+D + +P+ + Sbjct: 443 NSI-DDAFKIQNGKERSDAYKNILKQIDDEGIFIPISH 479 >5ICQ-A nrPDB Length = 610 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 116/535 (21%), Positives = 209/535 (39%), Gaps = 113/535 (21%) Query: 51 SLDPHKIE-GVPESNISRDLFEGLLVSDLDGHPA---PGVAESWDNKDAKVW-TFHLRKD 105 SL+P ++ G + ++F+GL+ D P P +A+S D A+ TFHL Sbjct: 76 SLNPFNVKSGTAAQGLVGNVFQGLMARSQD-EPFTLYPLIAQSIDIDPARTRVTFHLDPR 134 Query: 106 AKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAI 165 A +SDG P+TA+D ++S+ + P + YG + A Sbjct: 135 AHFSDGKPITAEDVLFSFD--LLKAKGRP-QQRIAYGLVK---------------SATAP 176 Query: 166 DDHTLEVTLSEPVPYFYKLLVHPSTSPV-PKAA--IEKFGEK-WTQPGNIVTNGAYTLKD 221 D H + L+ L++ + PV PK A +E+F + +P + +G Y + D Sbjct: 177 DPHRVAYDLTGVGDRELPLIL--AIMPVLPKHALDVERFSDATLAKP---LGSGPYVVAD 231 Query: 222 WVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQK 281 R++L+R P YW + +Q + + D+ +R G NS+ E F+ Sbjct: 232 VQAGARLLLKRDPNYW--GADIPSQRGFYNF--DEIDLQYFRDG------NSL-FEAFKA 280 Query: 282 LKKEIPDEVHVDPYLCTYYYE------------------------INNQKPPFNDVRVRT 317 + DE + Y + N ++ F D R+R Sbjct: 281 GLIDYRDETSTTRWSTGYDFPALRDGRMARESLKNENPKGLNGFVFNTRRALFKDARLRE 340 Query: 318 ALKLGMDRDII-----------------VNKVKAQGNMPA---YGYTPPYTDG--AKLTQ 355 A + D + + +++ + G + P+ D A++ + Sbjct: 341 AFGMMFDFEWVNANYYAGLYTRTKSFFDESELSSSGRGASEKERALLAPWPDAVRAEILE 400 Query: 356 PEWF-----GWSQEK-RNEEAKKLLAEAGYTAD--------KPLTINLLYNTSDLHKKLA 401 EW G +++ A LLA AG D +P + ++ D ++LA Sbjct: 401 GEWRPPVSDGSGRDRDMARRALDLLAAAGCRVDGDRLMKDGEPFSFEIMVKDRD-QERLA 459 Query: 402 IA-ASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY---NEPTSFLNTML 457 +A ASSL + + V V+LV++ + R + FD+ + A NE ++ Sbjct: 460 LAYASSLARIGVEVRVRLVDE--VQYQRRRQKFDFDMMIGQYVASASPGNEQRMRWSSAT 517 Query: 458 SN--SSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYY 510 +N SS N A SPA D +++ L + ++ L +VP+++ Sbjct: 518 ANQESSFNLAGAASPAIDGMISALLSARSQEDFVTAVRAYDRVLLSGFYVVPLFH 572 >4OEU-A nrPDB Length = 494 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 105/492 (21%), Positives = 189/492 (38%), Gaps = 91/492 (18%) Query: 38 KQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAK 96 K TL+ +E+ ++P E + +F GL D + P +A+SWD +KD Sbjct: 4 KDTLIIAVENEIARINPAYSED--HDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGL 61 Query: 97 VWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKP 156 V+ LR D W DG +A D +S + +P S + Y+ + I + EIL Sbjct: 62 VYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNS--SIYVNFEDIKSV-EIL----- 113 Query: 157 ITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPG-NIVTNG 215 + +++TL +P P F L S +PK +E + N + G Sbjct: 114 ---------NPSHVKITLFKPYPAFLDAL---SIGMLPKHLLENENLNTSSFNQNPIGTG 161 Query: 216 AYTLKDWVVNERIVLERSPTYW----NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMT- 270 Y W E + + + ++ + +I + IAS + + ID++ Sbjct: 162 PYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSL 221 Query: 271 -NNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIV 329 N E F L+++ D + ++N+ D++VR AL +D++ IV Sbjct: 222 LNIFKNDENFGILREKSAD-------YRALMFNLDNE--FLKDLKVRQALNYAVDKESIV 272 Query: 330 NKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRN-------EEAKKLLAEAGYTAD 382 + + Y + P W+ K ++A+ LL AG+ + Sbjct: 273 KNL-----LHDYAFVA--------NHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKN 319 Query: 383 KP---------LTINLLYNTSD-LHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQ 432 K L + ++D L LA S ++K IGV K+V + Sbjct: 320 KDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRK-IGVVSKVV---------AKPA 369 Query: 433 GTFDVARA-----GWCA----DYNEPTSF---LNTMLSNSSMNTAHYKSPAFDSIMAETL 480 G+FD ++ GW + D++ F ++ L++ N HY D + + Sbjct: 370 GSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKAR 429 Query: 481 KVTDEAQRTALY 492 ++ +R Y Sbjct: 430 NTSNLEERKKYY 441 >2D5W-A nrPDB Length = 603 Score = 42.7 bits (99), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 105/501 (20%), Positives = 184/501 (36%), Gaps = 114/501 (22%) Query: 102 LRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLG 161 +R DAKWSDG P+T +D + Y + G G+ + ++ Sbjct: 87 IRPDAKWSDGRPITTEDVAF----------------YFEVGKAKGMPVLNPDFWERVNVR 130 Query: 162 VKAIDDHTLEVTLSEPVPYFY-----------KLLVHPSTSPVPKAA--------IEKFG 202 +K + TL + EP Y+Y K ++ P V AA EK Sbjct: 131 IKDARNFTL---IFEPA-YYYDTYGPINTYAPKHIMGPEWERVKAAARGLDPDKDAEKLN 186 Query: 203 E-------KWTQP-----GNIVTNGAYTLKDWVVNERIVLERSPTY----WNNAKTVINQ 246 E K+ P G +V +G + LK WV I +ER+P + + + Sbjct: 187 ELYRNFFLKFATPQALNRGAMVYSGPFKLKRWVPGNSIEMERNPNFPIKPEGGESKYVQK 246 Query: 247 VTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQ----KLKKEIPDEVHV--DPYLCTYY 300 V Y I + + + G ID T +S+ + Q +L + P + P + Sbjct: 247 VVYRFIQNTNSLLVAVIGGSIDAT-SSVSLTFDQGRSPQLVRRAPGRFDIWFVPGAIWEH 305 Query: 301 YEINN-------QKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMP-AYGYTPPYTDGAK 352 +IN + ND R R A+ ++R+ +V K G P A+ + P Sbjct: 306 IDINKFENCQVVKDLGLNDKRTRQAILHALNREGLV-KAFFDGLQPVAHTWIAPVN---P 361 Query: 353 LTQPEWFGWSQEKRNEEAKKLLAEAGYTA--DKPLTINLLYNTSDLHKKLAIAASSLWK- 409 L P + + + EA LLAE G+ D L + T + A ++ + Sbjct: 362 LFNPNVKKYEFDLKKAEA--LLAEMGWRKGPDGILQRTVNGRTVRFEIEYVTTAGNVVRE 419 Query: 410 ----------KNIGVNVKLVNQEWKTFL---------DTRHQGTFDVARAGWCADYNEPT 450 K IG+ VK+ N + + G F+ A W ++ E Sbjct: 420 RTQQFFAEDLKKIGIAVKINNAPSAVVFADEFIQRASECKWTGMFEFA---WVSNLQEDG 476 Query: 451 SFLNTMLSNS-------------SMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQ 497 S N+ N +++ FD + ++ + D +R L+ +A++ Sbjct: 477 SLFQYKNLNTGAIMVPTKENNYQGQNIGGWRNDEFDRLTSQAVLEFDPERRKQLFWRAQE 536 Query: 498 QLDKDSAIVPVYYYVNARLVK 518 ++ +P+Y+ N +V+ Sbjct: 537 IWAEELPALPLYFRANPYVVR 557 >2GRV-A nrPDB Length = 621 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 69/301 (22%), Positives = 120/301 (39%), Gaps = 55/301 (18%) Query: 99 TFHLRKDAKWSDGTPVTAQDFVYSWQRSVD-PNTASPYASYLQYGHIAGIDEILEGKKPI 157 T+ +R +A+W+D P+ A D+ Y W++ V P P Y I G+ + GK+ + Sbjct: 120 TYKIRPEAQWTDNAPIAADDYWYLWRQMVSQPGVVDPAG----YDLITGVQSVEGGKQAV 175 Query: 158 TDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAY 217 VT S+P P + +L + + K FG + VT G + Sbjct: 176 --------------VTFSQPYPAWRELFNDILPAHIVKDIPGGFGAGLAR-AMPVTGGQF 220 Query: 218 TLKDW-VVNERIVLERSPTYWN-NAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMP 275 ++ + I+L R+ +W+ AK + V + + + R+G+ + Sbjct: 221 RVETIDPQRDEILLARNDRFWSVPAKP--DLVLFRRGGAPAALADSIRNGDTQVAQVHGG 278 Query: 276 IELFQKLKKEIPD---EVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDII---- 328 F +L IPD V P + + Q+P D +VR A+ +D D++ Sbjct: 279 AATFAQLSA-IPDVRTARIVTPRV--MQLTLRAQQPKLADPQVRKAILGLIDVDLLASVG 335 Query: 329 ------VNKVKAQGNMPA-YGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA 381 V +AQ P+ GY P T P ++A +LL +AGY + Sbjct: 336 AGDDNTVTLAQAQVRSPSDPGYVP--------TAPPAM------TRDDALELLRDAGYVS 381 Query: 382 D 382 + Sbjct: 382 E 382 >4XKN-A nrPDB Length = 473 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 83/360 (23%), Positives = 133/360 (36%), Gaps = 54/360 (15%) Query: 71 EGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPN 130 E L ++ G + +S+ + L+ + K+ +G +TA+ S + S+ + Sbjct: 37 ESLFKTNDQGKIEKALVKSYHQPNDTTLDIELKDNIKFQNGQKLTAEKVKSSLENSMKKS 96 Query: 131 TASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPST 190 Y+ PI+ + K L + + P L +P Sbjct: 97 DLVKYSL------------------PISSITAKG---QKLTIKTNSAYPELVSELANPF- 134 Query: 191 SPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYL 250 AI K V G Y +KD+ + +I L YW K ++ +T Sbjct: 135 -----MAIYDTDAKSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQ-GKPKLDHITVT 188 Query: 251 PIASEVTDVNRYRSGEIDM-----TNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINN 305 V S + D+ N IE Q LK + E L Y + N Sbjct: 189 YQEDGNNRVRNLESQKDDLITDVPVNKVQDIENNQNLK--VSKESGFRTSLLMYNH--TN 244 Query: 306 QKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPA---YGYTPPYTDGAKLTQPEWFGWS 362 +K + VR AL +DR I + + PA + PY KLT+ Sbjct: 245 KKMTKS---VREALDHIIDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNI---- 297 Query: 363 QEKRNEEAKKLLAEAGYTADKPLTINLL-YNTS-DLHKKLAIAASSLWKKNIGVNVKLVN 420 E+AK LLA+ GYT + PL I L+ Y+ +L K + S K NI +++K V+ Sbjct: 298 -----EQAKMLLAKDGYTKEHPLKIKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVD 352 >2WFN-A nrPDB Length = 278 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 55 HKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDA 95 +K+ +P +N SRD G + L APG+ WD+ DA Sbjct: 178 NKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDA 218 >3U48-A nrPDB Length = 775 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 2/33 (6%) Query: 511 YVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 Y+ A++ K V GY GKD DNT M VKH Sbjct: 152 YLGAQIAKAMVKGYQGKDFSDNTSI--MACVKH 182 >5HXA-A nrPDB Length = 483 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 12/80 (15%) Query: 323 MDRDIIV-NKVK--AQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGY 379 M R I+V N+V +G A G D K T WFGWS E +E + ++ + G Sbjct: 9 MSRLIVVSNRVAPTQEGRPAAGGLAIGVLDALKETGGVWFGWSGETVSEPSAPVIEKQG- 67 Query: 380 TADKPLTINLLYNTSDLHKK 399 N+ Y T L K+ Sbjct: 68 --------NVTYATVGLTKR 79 >5TRO-A nrPDB Length = 573 Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 113 PVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDE 149 P T +DF W + NT P +++ YG A I E Sbjct: 256 PETGKDFGKKWANDLYQNTYEPGSTFKSYGLAAAIQE 292 >4GM2-A nrPDB Length = 205 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 31/53 (58%) Query: 222 WVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSM 274 ++++RI+ SP Y + ++ +I+Q+ YL S+ ++ Y + D+ NN + Sbjct: 24 LLLSKRIIFLSSPIYPHISEQIISQLLYLEYESKRKPIHLYINSTGDIDNNKI 76 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3TCF-A nrPDB 684 0.0 1OLA-A nrPDB 658 0.0 2Z23-A nrPDB 629 e-180 6DQU-A nrPDB 553 e-158 3O9P-A nrPDB 541 e-154 3ZS6-A nrPDB 510 e-145 4GL8-A nrPDB 436 e-123 1DPE-A nrPDB 421 e-118 5F1Q-A nrPDB 417 e-117 5U4O-A nrPDB 415 e-116 3M8U-A nrPDB 401 e-112 4FAJ-A nrPDB 401 e-112 3TPA-A nrPDB 393 e-110 6NPO-A nrPDB 390 e-109 5KZT-A nrPDB 373 e-103 4QFK-H nrPDB 371 e-103 1UQW-A nrPDB 362 e-100 3MW0-A nrPDB 359 3e-99 4OER-A nrPDB 351 5e-97 6HLX-A nrPDB 344 5e-95 5ISU-A nrPDB 344 9e-95 1XOC-A nrPDB 318 4e-87 4PFT-A nrPDB 308 3e-84 4PFU-A nrPDB 308 4e-84 5YQW-A nrPDB 307 7e-84 1ZTY-A nrPDB 305 5e-83 5YH8-A nrPDB 295 3e-80 4OEU-A nrPDB 292 3e-79 3I5O-A nrPDB 286 2e-77 3T66-A nrPDB 285 3e-77 5ZA4-A nrPDB 278 3e-75 4ZE8-A nrPDB 277 1e-74 2WOP-A nrPDB 271 4e-73 4OFL-A nrPDB 247 1e-65 3DRH-A nrPDB 246 1e-65 2D5W-A nrPDB 242 3e-64 5ICQ-A nrPDB 240 1e-63 5IPW-A nrPDB 237 1e-62 4XKN-A nrPDB 231 6e-61 4ONY-A nrPDB 230 1e-60 6EQ0-A nrPDB 210 1e-54 2GRV-A nrPDB 156 2e-38 Sequences not found previously or not previously below threshold: 4WED-A nrPDB 212 3e-55 1NW1-A nrPDB 35 0.073 2PMP-A nrPDB 35 0.11 5JOS-A nrPDB 32 0.67 1WDT-A nrPDB 32 0.88 1VQZ-A nrPDB 31 1.3 5TUJ-C nrPDB 31 1.5 4EVS-A nrPDB 30 3.3 3V7C-A nrPDB 29 4.8 4DUR-A nrPDB 29 5.9 1XTP-A nrPDB 29 7.2 4F06-A nrPDB 28 9.0 3ZXV-A nrPDB 28 9.6 4B9G-A nrPDB 28 10.0 >3TCF-A nrPDB Length = 524 Score = 684 bits (1764), Expect = 0.0, Method: Composition-based stats. Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV Sbjct: 2 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 61 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG Sbjct: 62 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 121 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT Sbjct: 122 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 181 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE Sbjct: 182 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 241 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD Sbjct: 242 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 301 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT Sbjct: 302 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 361 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY Sbjct: 362 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 421 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV Sbjct: 422 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 481 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH Sbjct: 482 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 518 >1OLA-A nrPDB Length = 517 Score = 658 bits (1698), Expect = 0.0, Method: Composition-based stats. Identities = 443/517 (85%), Positives = 483/517 (93%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 ADVPAGV LA+KQTLVRNNGSEVQSLDPHKIEGVPESN+SRDLFEGLL+SD++GHP+PGV Sbjct: 1 ADVPAGVQLADKQTLVRNNGSEVQSLDPHKIEGVPESNVSRDLFEGLLISDVEGHPSPGV 60 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AE W+NKD KVWTFHLR++AKWSDGTPVTA DFVYSWQR DPNTASPYASYLQYGHIA Sbjct: 61 AEKWENKDFKVWTFHLRENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIAN 120 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 ID+I+ GKKP TDLGVKA+DDHT EVTLSEPVPYFYKLLVHPS SPVPK+A+EKFG+KWT Sbjct: 121 IDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWT 180 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QP NIVTNGAY LK+WVVNERIVLER+P YW+NAKTVINQVTYLPI+SEVTDVNRYRSGE Sbjct: 181 QPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVTYLPISSEVTDVNRYRSGE 240 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMT N+MPIELFQKLKKEIP+EV VDPYLCTYYYEINNQK PFNDVRVRTALKL +DRD Sbjct: 241 IDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLALDRD 300 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVK QG++PAY YTPPYTDGAKL +PEWF WSQ+KRNEEAKKLLAEAG+TADKPLT Sbjct: 301 IIVNKVKNQGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLT 360 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 +LLYNTSDLHKKLAIA +S+WKKN+GVNV L NQEWKTFLDTRHQGTFDVARAGWCADY Sbjct: 361 FDLLYNTSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADY 420 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEPTSFLNTMLS+SS NTAHYKSPAFD ++A+TLKV D+ QR+ LY KAEQQLDKDSAIV Sbjct: 421 NEPTSFLNTMLSDSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIV 480 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PVYYYVNARLVKPWVGGYTGKDPLDN Y +N+YI+KH Sbjct: 481 PVYYYVNARLVKPWVGGYTGKDPLDNIYVKNLYIIKH 517 >2Z23-A nrPDB Length = 517 Score = 629 bits (1621), Expect = e-180, Method: Composition-based stats. Identities = 404/517 (78%), Positives = 448/517 (86%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGV 86 A+VP GV LAEKQ LVRNNGSE QSLDPHKIEGVPESNISRDL EGL+++D +G+ PG Sbjct: 1 ANVPTGVQLAEKQVLVRNNGSEPQSLDPHKIEGVPESNISRDLLEGLVINDPNGNIVPGA 60 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AESWDNKD KVWTF++RKDAKWS+G PVTAQDFVYSWQR DP T SPYASYLQY H+ Sbjct: 61 AESWDNKDFKVWTFNIRKDAKWSNGDPVTAQDFVYSWQRLADPKTVSPYASYLQYAHLTN 120 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 ID+I+ GK LGVKA+DDHTLEVTLSEPVPY KLL HP SPV K +EKFGEKWT Sbjct: 121 IDDIITGKAAPDTLGVKALDDHTLEVTLSEPVPYLDKLLAHPLMSPVNKTVVEKFGEKWT 180 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 QP N V NGAY LKDW+VNERIVLERSPTYW+NAKTVINQVTYLPI+SEVTDVNRYRSGE Sbjct: 181 QPQNFVGNGAYKLKDWIVNERIVLERSPTYWDNAKTVINQVTYLPISSEVTDVNRYRSGE 240 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 IDMT N+MPIELFQKLKKEIPD+VHVDPYLCTYYYEINNQK PF D RVR ALKLGMDRD Sbjct: 241 IDMTYNNMPIELFQKLKKEIPDQVHVDPYLCTYYYEINNQKAPFTDARVREALKLGMDRD 300 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 IIVNKVK QG++PAYG+TPPYT GA+LT PEWF W+QEKRNE AKKLLAEAGYT D PL Sbjct: 301 IIVNKVKNQGDLPAYGFTPPYTSGAELTPPEWFSWTQEKRNEVAKKLLAEAGYTKDNPLK 360 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 +LLYNTSDLHKKLAIAA+S+WKKN+GV+VKL NQEWKTFLDTRHQGT+DVARA WCADY Sbjct: 361 FSLLYNTSDLHKKLAIAAASIWKKNLGVDVKLENQEWKTFLDTRHQGTYDVARAAWCADY 420 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 NEP+SFLN MLSNSS NT HYKS FD ++ +TLKV E +R LY +AE QLDKDSAIV Sbjct: 421 NEPSSFLNMMLSNSSNNTTHYKSSVFDKLIEDTLKVKSEKERADLYQQAEIQLDKDSAIV 480 Query: 507 PVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 PV+YYV+ARLVKP+VGGYTGKDPLDN + +++YI+K Sbjct: 481 PVFYYVSARLVKPYVGGYTGKDPLDNMHVKDLYIIKQ 517 >6DQU-A nrPDB Length = 530 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 279/519 (53%), Positives = 361/519 (69%), Gaps = 4/519 (0%) Query: 29 VPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAE 88 VP G L EKQ +V NNG+E QS DPHK EGVPESN++ L EGL+ SD +G PG AE Sbjct: 4 VPEGTQLDEKQHIVINNGAEPQSFDPHKTEGVPESNVAYQLLEGLVTSDSEGKLQPGAAE 63 Query: 89 SWDN-KDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGI 147 SW+N D K WTFHLRKDAKWS+G PVTA DFV++W+R VDP TA+PYASYL Y + Sbjct: 64 SWENTPDFKTWTFHLRKDAKWSNGDPVTAHDFVFAWRRLVDPATAAPYASYLSYLQVENA 123 Query: 148 DEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQ 207 +I++GKK +LGV+A DD+T V + PVPY L H S P+P+ +EK G+ W + Sbjct: 124 QDIIDGKKKPAELGVEAKDDYTFVVHATNPVPYAVSLTTHQSLLPLPQKVVEKLGDAWVK 183 Query: 208 PGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEI 267 N V NGAY L + ++NE+I ER+P YWN+ +TVIN T+L I + TDV RYR+G++ Sbjct: 184 KENYVGNGAYKLANHIINEKIEFERNPLYWNDKETVINSATFLAIENPSTDVARYRAGDL 243 Query: 268 DMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDI 327 DMT+ +P E F KLKKE+ EV+V L TY YE+NN+K PF++V +R AL L +DR++ Sbjct: 244 DMTSYGLPPEQFAKLKKELLGEVYVTRTLGTYSYELNNKKAPFDNVNIRKALNLSLDRNV 303 Query: 328 IVNKVKAQGNMPAYGYTPPYT-DGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLT 386 I +KV QG P Y +TP Y +G + QP + +RNEEA KLL EAGY+ PL Sbjct: 304 ITDKVLGQGQTPTYVFTPTYIEEGHLIQQPAYSKEPMAQRNEEAIKLLEEAGYSKANPLK 363 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIG--VNVKLVNQEWKTFLDTRHQGTFDVARAGWCA 444 ++LYNT++ HKK+AIAA+S+WK N ++VKL NQEWKT++D+R G +DVARAGW A Sbjct: 364 FSILYNTNENHKKVAIAAASMWKANTKGLIDVKLENQEWKTYIDSRRAGRYDVARAGWHA 423 Query: 445 DYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSA 504 DYN+ T+F N LSNSS NTA Y +P +D MAE+ TD R Y KAE+ L KD Sbjct: 424 DYNQATTFGNYFLSNSSNNTAKYANPEYDKAMAESYAATDAEGRAKAYAKAEEILGKDYG 483 Query: 505 IVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 IVP++ YVN RLVKP+V GY+GKDP D+ Y RN+YI+KH Sbjct: 484 IVPIFNYVNPRLVKPYVKGYSGKDPQDHIYLRNLYIIKH 522 >3O9P-A nrPDB Length = 519 Score = 541 bits (1394), Expect = e-154, Method: Composition-based stats. Identities = 252/519 (48%), Positives = 339/519 (65%), Gaps = 2/519 (0%) Query: 25 LAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAP 84 A+VP+G LAEKQ LVR+ E SLDP K G+PE + RDLFEGL+ + G P Sbjct: 3 AMAEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVP 62 Query: 85 GVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHI 144 GVA W + D ++WTF LR +AKW+DGTPVTAQDFVYSWQR VDP T SP+A + I Sbjct: 63 GVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGI 122 Query: 145 AGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEK 204 I++GK LGV A+D HTL++ L +P+P+F L + + PV KA +E G++ Sbjct: 123 NNAQAIIDGKATPDQLGVTAVDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVES-GKE 181 Query: 205 WTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRS 264 WT+PGN++ NGAY LK+ VVNE++V+ + YW+NAKTV+ +VT+LPI E RY + Sbjct: 182 WTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLA 241 Query: 265 GEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMD 324 G+ID+T S P ++QKL K+IP +V+ P L TYYY N QK P D RVR AL + +D Sbjct: 242 GDIDITE-SFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTID 300 Query: 325 RDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKP 384 R ++ KV G PA+ +TP T G + SQE+ N +AK LL+ AGY KP Sbjct: 301 RRLMTEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKP 360 Query: 385 LTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCA 444 L + LLYNTS+ H+K+AIA +S+WKKN+GV+VKL NQEWKT++D+R+ G FDV RA W Sbjct: 361 LKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVG 420 Query: 445 DYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSA 504 DYNEP++FL + S S N + + +PA+D ++A+ R A Y AE+ L + + Sbjct: 421 DYNEPSTFLTLLTSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAP 480 Query: 505 IVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH 543 I P+Y Y N RL+KPW+ GY +P D Y+R MYIVKH Sbjct: 481 IAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH 519 >3ZS6-A nrPDB Length = 506 Score = 510 bits (1314), Expect = e-145, Method: Composition-based stats. Identities = 220/509 (43%), Positives = 306/509 (60%), Gaps = 4/509 (0%) Query: 35 LAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKD 94 LA++Q L R +EV+SLDP IE + I DLFEGL D G PGVA++W++K Sbjct: 1 LADQQDLTRQVPAEVESLDPAHIESWTGNTIGLDLFEGLARIDASGAVVPGVAQAWEHKA 60 Query: 95 AKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGK 154 W F LR+DAKWS+G PVTA DFVY+WQR DP T S Y +++ + I+ GK Sbjct: 61 PDTWIFKLRRDAKWSNGQPVTAADFVYAWQRLADPKTGSKYTILVEF--VKNASAIIAGK 118 Query: 155 KPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTN 214 +P DLG++AID +T+EV PV YF +L +PV K A+ KFG+ WT+P NIV+N Sbjct: 119 QPPGDLGIRAIDPYTIEVKTEVPVSYFPELTAMAPLTPVNKDAVAKFGDAWTRPKNIVSN 178 Query: 215 GAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSM 274 G YTL DW N RIV+ +S YWN VI +VTYLPI ++ T + Y++G+ID T S+ Sbjct: 179 GPYTLVDWQPNNRIVMAKSDKYWNARNVVIRKVTYLPIENDETALRMYQAGQIDYT-YSI 237 Query: 275 PIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA 334 P F ++ K+ E+ L TYYY + N P D RVR AL + +DR+I+ +K+ Sbjct: 238 PAGGFGQISKQFGKELRPGLQLATYYYYLKNSDPALKDKRVREALAMVLDREILTSKITQ 297 Query: 335 QGNMPAYGYTPPYTDGAK-LTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNT 393 G +P YG P G + P+W W +R + AK LL +AG+ PLT L YNT Sbjct: 298 AGEVPMYGLMPKGVKGVQRPFTPDWASWPMARRVDYAKNLLKQAGHGDANPLTFTLTYNT 357 Query: 394 SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFL 453 +DLHKK+A+ A+S W+ +GV KL N E+K + RH G +AR GW ADYN+ +F Sbjct: 358 NDLHKKVALFAASEWRTKLGVTAKLENVEFKVLMKQRHDGKVQIARDGWFADYNDAMTFF 417 Query: 454 NTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVN 513 + + SS NT Y +P DS++AE + D+ R AL T+A D +VP++ Y Sbjct: 418 DLIRCGSSQNTVGYCNPKVDSLVAEANQKLDDGARAALLTQAHDLAMNDYPMVPLFQYSA 477 Query: 514 ARLVKPWVGGYTGKDPLDNTYTRNMYIVK 542 RLVK +VGGYT + +D +++MY++K Sbjct: 478 DRLVKSYVGGYTLTNYIDMRASQDMYLIK 506 >4GL8-A nrPDB Length = 529 Score = 436 bits (1122), Expect = e-123, Method: Composition-based stats. Identities = 165/505 (32%), Positives = 274/505 (54%), Gaps = 16/505 (3%) Query: 21 GNVALAADVPAGVTLAEKQTLVR--NNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSD- 77 G + P + + + LV N GSE +LD I S I +F G+L D Sbjct: 10 GTLEAQTQGPGSMNESNRNKLVFKLNIGSEPATLDAQLINDTVGSGIVSQMFLGILDGDP 69 Query: 78 LDGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYA 136 G PG+A+SWD + D V+TFHLR + WSDG +TA+ S+ R +D T S + Sbjct: 70 RTGGYRPGLAKSWDISDDGVVYTFHLRDNLVWSDGVSITAEGIRKSYLRILDKETGSSFV 129 Query: 137 SYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA 196 + ++ I +E +GK ++LG+KA+D+ TLE+TL P PYF +LVH + PVP Sbjct: 130 NMIK-SVIKNAEEYFDGKANESELGIKALDEKTLEITLKSPKPYFLDMLVHQTFIPVPMH 188 Query: 197 AIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEV 256 IEK+G++WT P N+V +G + LK V+NE++VLE++ Y+N+ V++ + + + + Sbjct: 189 VIEKYGQRWTDPENMVVSGPFKLKSRVLNEKVVLEKNNKYYNSKDVVLDSIIFFVTDNSI 248 Query: 257 TDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVR 316 T N Y + E+D ++P +L + LK + D+ + T +Y +N + P ++V+VR Sbjct: 249 TAYNMYLNDELDAIFKNVPPDLLKDLK--LRDDYYSMGINSTSFYSLNMKVKPLDNVKVR 306 Query: 317 TALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE 376 AL +DR + V ++P TP Y D + + F E AKKLLA+ Sbjct: 307 KALSFAIDRKTLTESVLNDSSIPTRRATPDYIDYSYKSNLSLF------DAEMAKKLLAD 360 Query: 377 AGYTADKPLT-INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTF 435 AGY + + YNTSD +K+A + WKKN+ +NV+L N+EW T++++R G + Sbjct: 361 AGYPNGNNFPLLKVKYNTSDSQRKIAEFIQNQWKKNLNINVQLENEEWSTYINSRVNGNY 420 Query: 436 DVARAGWCADYNEPTSFLNTMLS-NSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTK 494 ++ R+GW DY +P +FL+ + N+S ++ Y + +D ++ ++ D +R + K Sbjct: 421 EIIRSGWSGDYADPMTFLSIFQTENTSFSSYGYSNSEYDELLIKSDNERDIFKRQEILKK 480 Query: 495 AEQQLDK-DSAIVPVYYYVNARLVK 518 AE + + D V + ++ L + Sbjct: 481 AEAIIIERDFPAVFLNITSSSYLFR 505 >1DPE-A nrPDB Length = 507 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 123/523 (23%), Positives = 206/523 (39%), Gaps = 38/523 (7%) Query: 39 QTLVRNNGSEVQSLDPHK-IEGVPESNISRDLFEGLLVSDL-DGHPAPGVAESWD-NKDA 95 +TLV + + +P I G S L+ L+ + PG+AE W+ ++D Sbjct: 1 KTLVYCSEGSPEGFNPQLFISGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDG 60 Query: 96 KVWTFHLRKDAKWSDGTPV------TAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDE 149 K +TFHLRK KW D A D V+S+ R + S Y + G+ Sbjct: 61 KTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMG- 119 Query: 150 ILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIE---KFGEKWT 206 P VK +DD+T++ L+ P F L S + K + K G Sbjct: 120 -----LPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEK 174 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 N + G + L+ + + RI + YW K I+ + + + + E Sbjct: 175 LDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGT-KPQIDTLVFSITPDASVRYAKLQKNE 233 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 + P ++ ++K++ + P L Y N QK P +DV+VR AL +++D Sbjct: 234 CQVMPYPNPADI-ARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKD 292 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKP-- 384 I+ V + A PP G ++ E+AK LL EAG Sbjct: 293 AIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYT-----YDPEKAKALLKEAGLEKGFSID 347 Query: 385 ---LTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAG 441 + + YN + +++A + W K +GV K+V EW +L G G Sbjct: 348 LWAMPVQRPYNPN--ARRMAEMIQADWAK-VGVQAKIVTYEWGEYLKRAKDGEHQTVMMG 404 Query: 442 WCADYNEPTSFLNTMLSNSS----MNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQ 497 W D +P +F T S ++ N + + F+ ++ D +R LY +A+ Sbjct: 405 WTGDNGDPDNFFATEFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQV 464 Query: 498 QLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYI 540 + + + + + V+ V GY DPL + N+ I Sbjct: 465 VMHDQAPALIIAHSTVFEPVRKEVKGYV-VDPLGKHHFENVSI 506 >5F1Q-A nrPDB Length = 543 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 119/551 (21%), Positives = 216/551 (39%), Gaps = 51/551 (9%) Query: 11 AAGVLAALMAGNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHK-IEGVPESNISRDL 69 G++A +A +V +TLV + + +P G S + Sbjct: 14 GIGLVALTIAASVQA-------------KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPI 60 Query: 70 FEGLLVSDL-DGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPV------TAQDFVY 121 + L+ + P +AE W+ ++D K +TF+LRK KW D A D +Y Sbjct: 61 YNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIY 120 Query: 122 SWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYF 181 S+ R D S Y + G+ V +DD+T+ L+ P F Sbjct: 121 SFMRQKDDKNPYHKVSGGSYEYFQGMG------MGDLITNVVKVDDNTVRFELTRPESPF 174 Query: 182 YKLLVHPSTSPVPKAAIE---KFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWN 238 L S + + K G N + G + L+ + + RI+ + P +W Sbjct: 175 LADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWG 234 Query: 239 NAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCT 298 K I+++ + + + E + P ++ ++K++ + P L Sbjct: 235 T-KPKIDRLVFSITPDASVRYAKLQKNECQIMPYPNPADI-ARMKEDKTINLMEQPGLNV 292 Query: 299 YYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEW 358 Y N +K P ++++VR AL + +++D I++ V A PP G ++ Sbjct: 293 GYLSFNIEKKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDY 352 Query: 359 FGWSQEKRNEEAKKLLAEAGYTADKP-----LTINLLYNTSDLHKKLAIAASSLWKKNIG 413 +AK+LL EAG + + YN + +++A S W K IG Sbjct: 353 -----AYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPN--ARRMAEMIQSDWAK-IG 404 Query: 414 VNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSM----NTAHYKS 469 V K+V EW +L G + GW D +P +F T+ S + N + + Sbjct: 405 VKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCY 464 Query: 470 PAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDP 529 F+ ++ D +R ALY +A+ +++ + + + + V+ V GY DP Sbjct: 465 KPFEDLIQPARAEADHDKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYV-VDP 523 Query: 530 LDNTYTRNMYI 540 L + N+ + Sbjct: 524 LGKHHFDNVSL 534 >5U4O-A nrPDB Length = 521 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 124/547 (22%), Positives = 219/547 (40%), Gaps = 42/547 (7%) Query: 6 KRSLVAAGV----LAALMAG---NVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIE 58 KR LV+ + L+ +AG N + E L S+ +LDPH I Sbjct: 4 KRGLVSCFIAILCLSVFLAGCSSNAKTGNEGSGSKGTKEGGVLTIARLSDADNLDPHFIT 63 Query: 59 GVPESNIS-RDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQ 117 +P +++ ++E L+ D + P +A+ W D W F L++ + DG P A+ Sbjct: 64 NIPSASVVYHKVYENLVQRDKNMDFKPMLAKEWKQIDDLNWEFKLQQGVTFQDGAPFNAE 123 Query: 118 DFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEP 177 +++R +DP S A+ +K ID++T++ L P Sbjct: 124 AVKKNFERVLDPKVGSNRATVYSMIQ-----------------EIKVIDEYTVQFILKYP 166 Query: 178 VPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYW 237 + S + AI++ G+ Q + V G YT K W E I LE++ YW Sbjct: 167 YSPLLSIFASNEGSILSPKAIDEKGKGLAQ--HPVGTGPYTFKSWKPGEEIRLEKNKNYW 224 Query: 238 NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLC 297 K +++V + + + T + + E + N +P+ +++K E+ + L Sbjct: 225 GE-KAKVDEVVFKVVPEDATRIGMIETSEAHIAEN-LPVTEVERVKNSPSMELIENEGLG 282 Query: 298 TYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPE 357 Y N +K PF++ VR A+ ++ I+ V P G + Sbjct: 283 VEYIGFNVEKKPFDNPLVRQAIAHAIETKGILKGVYNNVGTEINSVMTPKVFG---YTKD 339 Query: 358 WFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVK 417 G+ + AKKLLA+AGY TI N S + L S K IGV+V+ Sbjct: 340 VKGYKYDINT--AKKLLADAGYPNGFKTTI--WTNDSKVRMALVEVIQSQL-KGIGVDVE 394 Query: 418 LVNQEWKTFLDTRHQGTFDVARAGWCADYNE----PTSFLNTMLSNSSMNTAHYKSPAFD 473 + E+ FL ++ + GW + + ++ ++ N Y +P D Sbjct: 395 IKVMEYGAFLAATNKSEHAMFVGGWGNATGDGDYNQYNLFHSSSHGATGNQFFYSNPEVD 454 Query: 474 SIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNT 533 ++ E K DE +R LY + ++ KD+ +VP+ + + G+ DP Sbjct: 455 KLIEEARKEKDETKRKELYKQLQEIELKDALLVPIRGINHIAATTKNIKGFWI-DPSGYL 513 Query: 534 YTRNMYI 540 + + Sbjct: 514 RLEGVEL 520 >3M8U-A nrPDB Length = 522 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 120/515 (23%), Positives = 224/515 (43%), Gaps = 33/515 (6%) Query: 39 QTLVRNNGSEVQSLDPHKI-EGVPESNISRDLFEGLLVSDL-DGHPAPGVAESWD-NKDA 95 +T + P + +G+ + S+ ++ L+ P +AESW + D Sbjct: 3 KTFINCVSRSPTGFSPALVMDGISYNASSQQVYNRLVEFKRGSTDIEPALAESWTVSDDG 62 Query: 96 KVWTFHLRKDAKWSDGTPVT------AQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDE 149 +TF+LRK K+ T A D V+S+QR +DPN S Y + + Sbjct: 63 LTYTFNLRKGVKFHSNKEFTPSRDFNADDVVFSFQRQLDPNHPYHNVSKATYPYFKAM-- 120 Query: 150 ILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKF---GEKWT 206 K V+ +D HT+++TL+ F L S +K G+ T Sbjct: 121 ----KFSTLLKSVEKVDMHTVKITLNRQDATFLASLGMDFISIYSAEYADKMLAAGKPET 176 Query: 207 QPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGE 266 + G + + V+++ YW K I+++ + + + ++G Sbjct: 177 IDTTPIGTGPFLFAGYQVDQKSRYLAHKEYWK-GKADIDRLIFEIVPDATARYAKLQAGA 235 Query: 267 IDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD 326 D+ + +L +K+K + +H L Y N +K PF++V+VR AL +D++ Sbjct: 236 CDLIDFPNAADL-EKMKTDPKVNLHSQSGLNIAYIAFNTEKAPFDNVKVRQALNYAVDKN 294 Query: 327 IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA--DKP 384 I++ V + A PP G E G+ E E+AK+LL EAG+ + Sbjct: 295 AIIDAVYRGAGVAAKNPLPPTIWG---YNNEITGY--EYSPEKAKQLLKEAGFENGFETD 349 Query: 385 LTINLLYNTSDLH-KKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWC 443 + + + S+ + +++A S W+K +GV KLV+ EW ++ G GW Sbjct: 350 IWVQPVVRASNPNPRRMAELVQSDWEK-VGVKSKLVSYEWGDYIKRTKAGELTAGTYGWS 408 Query: 444 ADYNEPTSFLNTMLSNSSM---NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLD 500 D +P +FL+ + + ++ N A +K+P D+++ + + ++D+A+R +Y +A+ L Sbjct: 409 GDNGDPDNFLSPLFGSENVGNSNYARFKNPELDALLHKAVGLSDKAERAKIYEQAQVLLK 468 Query: 501 KDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYT 535 + + + V + +N V Y + P TY Sbjct: 469 EQAPWINVAHSINFAPTSKRVQDYK-QSPFGYTYL 502 >4FAJ-A nrPDB Length = 564 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 144/540 (26%), Positives = 244/540 (45%), Gaps = 31/540 (5%) Query: 1 MTNITKRSLVAAGVLAALMA--GNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIE 58 M K + G+L ++A G D +Q G+ VQSLDP Sbjct: 20 MKKYKKFCFLGIGLLPLVLASCGTNTATKDSQDATEKKVEQVATLTAGTPVQSLDPATAV 79 Query: 59 GVPESNISRDLFEGLLVSDLDGHPAPGVAESWD--NKDAKVWTFHLRKDAKWSDGTPVTA 116 + ++ EGL D P P +A + + K +T +R AKWSDGT +TA Sbjct: 80 DQTSITLLANVMEGLYRLDEKNQPQPAIAAGQPKVSNNGKTYTIVIRDGAKWSDGTQITA 139 Query: 117 QDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSE 176 DFV +WQR VDP T SP + I EI GK+ L VK+I + TLE+ L E Sbjct: 140 SDFVAAWQRVVDPKTVSPNVEL--FSAIKNAKEIASGKQAKDTLAVKSIGEKTLEIELVE 197 Query: 177 PVPYFYKLLVHPSTSPVPKAAIEKFGEKW-TQPGNIVTNGAYTLKDWV---VNERIVLER 232 P PYF LL + PV + AI+++G+ + IVTNGA+ L + +++ + + Sbjct: 198 PTPYFTDLLSLTAYYPVQQKAIKEYGKDYGVSQKAIVTNGAFNLTNLEGVGTSDKWTISK 257 Query: 233 SPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHV 292 + YW+ ++++ + + T +N Y G++D + E ++ KK+ E Sbjct: 258 NKEYWDQKDVSMDKINFQVVKEINTGINLYNDGQLD--EAPLAGEYAKQYKKD--KEYST 313 Query: 293 DPYLCTYYYEINN--QKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDG 350 T + E+N + + VR A+ +DR+ +V K+ G++ + G P Sbjct: 314 TLMANTMFLEMNQTGENKLLQNKNVRKAINYAIDRESLVKKLLDNGSVASVGVVPKEMAF 373 Query: 351 AKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPL------TINLLYNTSDLHKKLAIAA 404 + + ++ + EK E KK E A K + +++LL + + KK Sbjct: 374 NPVNKKDF---ANEKLVEFNKKQAEEYWDKAKKEIDLSKNTSLDLLVSDGEFEKKAGEFL 430 Query: 405 SSLWKKNI-GVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMN 463 + ++ G+ V + F++ + F ++ +GW ADY +P SFL +NS MN Sbjct: 431 QGQLQDSLEGLKVTVTPIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMN 490 Query: 464 TAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGG 523 Y + +D ++ ++ ++R KAE+ L D +VP++ A+L K + Sbjct: 491 HGGYSNKNYDELLKDS-----SSKRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKIKN 545 >3TPA-A nrPDB Length = 521 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 124/523 (23%), Positives = 222/523 (42%), Gaps = 33/523 (6%) Query: 36 AEKQTLVRNNGSEVQSLDPHKIEGVPE-SNISRDLFEGLLVSDL-DGHPAPGVAESWD-N 92 A TLV + L P + + S+ ++ L+ PG+AE W+ + Sbjct: 5 APTNTLVNCIATAPMKLSPAITNDANDFNASSQQVYNRLVEFKAGKIEVEPGLAERWEIS 64 Query: 93 KDAKVWTFHLRKDAKWSDGT------PVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 +D V+TF+LR++ K+ P+ A D V+S+QR D N S Y + Sbjct: 65 EDGLVYTFYLRQNVKFHSNKTFSPTRPLNADDVVFSFQRQADKNHPYHNVSAGTYFYFNW 124 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKF---GE 203 ++ P V+ +DD+T+++TL++P F + S K ++ G+ Sbjct: 125 MN------LPSILKSVEKVDDYTVKITLNKPNTPFITTVAMDFLSIYSKEYADQLLAQGK 178 Query: 204 KWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYR 263 T + G + + + + + YW K I ++ + T + + Sbjct: 179 PETLDQQPIGTGPFIFQTNQTDHAVRYTANVDYWK-GKADIERLIFSITPDAGTRYAKLK 237 Query: 264 SGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGM 323 +GE D+ + I ++KK+ + L Y +N KP N+V+VR AL Sbjct: 238 AGECDVIDFPN-ISDIAQMKKDPQINLLEREGLNLAYIGLNTTKPELNNVKVRQALHHAT 296 Query: 324 DRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA-- 381 D+ IV+ V G A P+ D P + E E+AK LLAEAGY Sbjct: 297 DKKAIVDAVYQGGGTVATN---PFPDAVLGYNPHLPQY--EFNLEKAKALLAEAGYPNGF 351 Query: 382 DKPLTINLLYNTSDLH-KKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARA 440 + + + + S+ + ++ A + W K IGV KLV EW F +G F Sbjct: 352 ETEIWVQPVVRPSNPNPRRTAEIIQADWAK-IGVKAKLVTHEWADFNKRTREGEFAAGTY 410 Query: 441 GWCADYNEPTSFLNTMLSNSSM---NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQ 497 GW + +P +FL + S +++ N + + F++++A ++ D R LY +A + Sbjct: 411 GWTSRNGDPDNFLFPLFSQANIPGTNYSRWTDEKFEALLASAAQIQDTQTRAKLYQQAVE 470 Query: 498 QLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYI 540 ++S I+P + +N + V G+ ++P T + + Sbjct: 471 IFQQNSPIIPFAHSINYVPLNKRVQGFV-QNPFGYTAFYGVSL 512 >6NPO-A nrPDB Length = 546 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 157/535 (29%), Positives = 256/535 (47%), Gaps = 20/535 (3%) Query: 22 NVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGH 81 N + D + LA KQ + E+ ++D K S I + EGL D + Sbjct: 17 NSSSGGDSKSEEKLAAKQVFNKTENQEIPTMDTSKSTDTLGSQILGNTMEGLYRLDKENK 76 Query: 82 PAPGVAES-WDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQ 140 P P AES ++D K +TF LRKDAKWS+G VTA+DFV++WQR +DP TA+ YA Sbjct: 77 PIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDSVTAKDFVFAWQRLLDPKTAAEYAFIA- 135 Query: 141 YGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEK 200 I + + +G+KP+T+LGVKA+DD TLEV L + VPYF L+ PS P+ + +++ Sbjct: 136 -FPIKNAEAVNKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKE 194 Query: 201 FGEKW-TQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDV 259 G+K+ + V NG + L DW + L+++ YW+ ++++ Y + T+V Sbjct: 195 KGDKYGLESDTTVYNGPFVLTDWKHEQGWKLKKNDQYWDKKTVKLDEINYSVVKEPATNV 254 Query: 260 NRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQK----PPFNDVRV 315 N Y SG+ID S+ F + +E V T++ +N ++ P ++ Sbjct: 255 NLYDSGQIDF---SLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGGQDTPLKSKKL 311 Query: 316 RTALKLGMDRDIIVNKVKAQGNMPAYGYTPPY----TDGAKLTQPEWFGWSQEKRNEEAK 371 R A+ L +D+ + N + G+ PA P DG + G + + A Sbjct: 312 REAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVKPDAKKAAAA 371 Query: 372 KLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNI-GVNVKLVNQEWKTFLDTR 430 A+ D+ +TI L + KK+ +KN+ GV V + Q +K L Sbjct: 372 WEEAKKELGKDQ-VTIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLE 430 Query: 431 HQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAET--LKVTDEAQR 488 +D++ GW DY +P ++L+ S S N + +D I+ + +TD +R Sbjct: 431 SDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQMSFSDQKYDEIIKKAGGELMTDAKKR 490 Query: 489 TALYTKAEQQLD-KDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVK 542 KAE+ L +D A+VP+Y + ++KP V G + + Y+ + Sbjct: 491 WEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKGVVKHNISPEYSYKWAYVTE 545 >5KZT-A nrPDB Length = 536 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 156/536 (29%), Positives = 251/536 (46%), Gaps = 30/536 (5%) Query: 27 ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPA-PG 85 + +Q L + + S D K + N+ EGL D DG PA G Sbjct: 3 KKGSDSGKASGEQVLNLTESALIPSADSTKADDQVGLNVVNQTNEGLYALDKDGIPAIAG 62 Query: 86 VAESWDNKDAKV-WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHI 144 AE D K +T LR+DAKWS+G PVTA D+VYSW+R+VDPNTA+ Y+ + I Sbjct: 63 AAEEPKISDDKTVYTIKLREDAKWSNGDPVTANDYVYSWRRAVDPNTAATYS--YLFDAI 120 Query: 145 AGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEK 204 +I+ GKK +LG+KA+DD+TLEVTLS+P Y L P+ P+ + + + GEK Sbjct: 121 KNGGDIVAGKKKPEELGIKAVDDYTLEVTLSKPTAYINSLFAFPTFFPLNEKFVTEKGEK 180 Query: 205 WTQP-GNIVTNGAYTLKDWV-VNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRY 262 + Q N++ NG + LKDW N++ ++ YW+ K + Q+ + T +N Y Sbjct: 181 YAQNSDNMLFNGPFELKDWTGTNKKWTYVKNDKYWDKDKVKLKQINVQVVQDSGTGLNLY 240 Query: 263 RSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPP----FNDVRVRTA 318 + ++D T + + + K T+Y + N ++ F + +R A Sbjct: 241 NTDKVDRTV--LSADYAAQNKNNKD--YVTVNNSSTFYIKFNQKRAGKDTVFANKNIRKA 296 Query: 319 LKLGMDRDIIVNKVKAQGNMPAYGYTP---PYTDGAKLTQPEWFGWSQEKRNEEA----K 371 + L +D+ + V G+ PA P + G K + G E +EA K Sbjct: 297 IALAIDKQSYTDTVLKNGSKPANNLVPEGFTFDPGNKEDYTKESGKHLEYDVKEAQKAWK 356 Query: 372 KLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNI-GVNVKLVNQEWKTFLDTR 430 L E G +T+ + ++ +K + +KN+ G+ VKL N +K L Sbjct: 357 AGLKELGV---NEITVEFTSDDTENARKSSEFIQDQLQKNLDGLTVKLKNVPFKVRLQND 413 Query: 431 HQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKV--TDEAQR 488 +D + +GW DY +P++FL+ +++ + N Y + +D I+ + D+ +R Sbjct: 414 QNQDYDFSMSGWGPDYQDPSTFLDLFVTDGAQNRMSYSNKDYDKILNDASVTYAADDQKR 473 Query: 489 TALYTKAEQQLD-KDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYT-RNMYIVK 542 KAE+ L D AI P+Y A L K ++ K+P YT + Y+ K Sbjct: 474 WDEMVKAEKILLTDDVAIQPLYQRSTAYLQKDYIKNLQ-KNPFGPDYTYKETYLTK 528 >4QFK-H nrPDB Length = 541 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 121/530 (22%), Positives = 215/530 (40%), Gaps = 36/530 (6%) Query: 28 DVPAGVTLAEKQTLVRNNGSEVQSLDPH-KIEGVPESNISRDLFEGLLVSD-LDGHPAPG 85 D + + Q LV + S +P G I+ L++ L+ D + Sbjct: 18 DSKEEILEEKNQGLVYCAEANPVSFNPQVTTTGSTIDIIANQLYDRLISIDPVTAEFKSE 77 Query: 86 VAESWD-NKDAKVWTFHLRKDAKWSDGTPVT------AQDFVYSWQRSVDPNTASPYASY 138 +A W +KD K TF LRK K+ T A D ++++ R D + Sbjct: 78 LATDWKISKDGKSVTFTLRKGVKFHTTAYFTPTREFNADDVIFTFSRLFDVYNPYHFVGD 137 Query: 139 LQYGHI--AGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA 196 Y + GID+++ ++D V+ + L+ F +L + Sbjct: 138 ANYPYFQSVGIDQLIRKIVRVSDHQVRFELFNAESSFLANMATDFAVVLSKEYAMALKAN 197 Query: 197 AIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEV 256 E +++ V G Y K++ + + ++ YW + + + Q+ Y + Sbjct: 198 NQENLFDQY-----PVGTGPYIYKEYRRDHLVRFYKNADYWKH-EVALEQLVYDITPNGT 251 Query: 257 TDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVR 316 T + + + E D+T + +L L + V + L Y+ N ++PPF++++VR Sbjct: 252 TRIAKILTKECDVTAHPSSAQL-SILAQRDDINVERETNLNIGYWAFNTERPPFDNLKVR 310 Query: 317 TALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE 376 AL +D + I+ V + A PP + + + + AKKLL E Sbjct: 311 QALVHAIDIEKIMQAVYYGNGLRARSILPPTSWAFEPQKN-----MPIFDPQLAKKLLTE 365 Query: 377 AGYTADKPLTI-----NLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRH 431 AGY ++I + +YN + +K+A S +K IGVNV +V EW TF+ Sbjct: 366 AGYEKGFDMSIWAMPVSRIYNPN--ARKMAELMQSDLRK-IGVNVNIVEYEWNTFIQRIG 422 Query: 432 QGTFDVARAGWCADYNEPTSFLNTMLSN----SSMNTAHYKSPAFDSIMAETLKVTDEAQ 487 + D GW AD +P +F + +LS S N A++ +P FD ++ + L TD Sbjct: 423 EHRHDSVLLGWAADTPDPDNFFSPLLSCTATFSGKNPANWCNPEFDLLLTKALDTTDLNL 482 Query: 488 RTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRN 537 R Y A+ + + + P+ + + + V G T P N Sbjct: 483 RKQYYDAAQSMIIEQLPLYPIAHGMRFQASSADVEGITL-GPFGAISLAN 531 >1UQW-A nrPDB Length = 509 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 120/495 (24%), Positives = 211/495 (42%), Gaps = 35/495 (7%) Query: 39 QTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAKV 97 + +V GS +LDP+ +++ ++GL D + +AES+ + D Sbjct: 25 KDVVVAVGSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGIT 84 Query: 98 WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPI 157 +T LR+ K+ DGT A + R+ DP A+ + Y +IA Sbjct: 85 YTVKLREGIKFQDGTDFNAAAVKANLDRASDP--ANHLKRHNLYKNIAKT---------- 132 Query: 158 TDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAY 217 +AID T+++TL +P F +L HP+T+ + AA+EK+G++ V G Y Sbjct: 133 -----EAIDPTTVKITLKQPFSAFINILAHPATAMISPAALEKYGKEIG--FYPVGTGPY 185 Query: 218 TLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIE 277 L W + + +++ YW ++ +T+ P+A T ++GE +P E Sbjct: 186 ELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQFA-FPIPYE 244 Query: 278 LFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGN 337 L+K E+ P + Y +N + PF++ +VR AL ++R +V A Sbjct: 245 QATLLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYA 304 Query: 338 MPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLH 397 PA G PP A+ +P W + +A++LL EAGY T+ +N S Sbjct: 305 TPATGVVPPSIAYAQSYKP----WPYDPV--KARELLKEAGYPNGFSTTLWSSHNHSTAQ 358 Query: 398 KKLAIAASSLWKKNIGVNVKLVNQEWKTFL---DTRHQGTFDVARAGWCADYNEPTSFLN 454 K L L + I V ++ + + + + GW A E L+ Sbjct: 359 KVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEADWALS 418 Query: 455 TMLSNSSM-----NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVY 509 + ++ + NTA Y + D +A+ LK D A++T LY A+ + ++S +P+ Sbjct: 419 PLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPWIPLV 478 Query: 510 YYVNARLVKPWVGGY 524 + G+ Sbjct: 479 VEKLVSAHSKNLTGF 493 >3MW0-A nrPDB Length = 502 Score = 359 bits (920), Expect = 3e-99, Method: Composition-based stats. Identities = 117/512 (22%), Positives = 206/512 (40%), Gaps = 50/512 (9%) Query: 36 AEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDL-FEGLLVSDLDGHPAPGVAESW-DNK 93 A + V L+PH P ++ + +E L+ DG P +A+SW ++ Sbjct: 1 AAPDEITTAWPVNVGPLNPHLY--TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSE 58 Query: 94 DAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEG 153 D K WTF LR D K+S+G P A+ +++ +D + ++ + ++I++ Sbjct: 59 DGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLD--------NRQRHAWLELANQIVD- 109 Query: 154 KKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPG--NI 211 VKA+ L++TL F + L P P A +F T G Sbjct: 110 --------VKALSKTELQITLKSAYYPFLQELALP--RPFRFIAPSQFKNHETMNGIKAP 159 Query: 212 VTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM-- 269 + G + L++ +N+ V R+ YW K I ++T+ I T + +G+ID+ Sbjct: 160 IGTGPWILQESKLNQYDVFVRNENYWGE-KPAIKKITFNVIPDPTTRAVAFETGDIDLLY 218 Query: 270 -TNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDII 328 +P++ F + + + + T +N K P N++ VR AL +++ + Sbjct: 219 GNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSL 278 Query: 329 VNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGY--------- 379 ++ A P A L + ++AK LL +AG+ Sbjct: 279 IDNALYGTQQVADTLFAPSVPYANLGLKP-----SQYDPQKAKALLEKAGWTLPAGKDIR 333 Query: 380 -TADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD-V 437 +PL I L + +D K + IG +V L+ +E + + G F + Sbjct: 334 EKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMI 393 Query: 438 ARAGWCADYNEPTSFLNTMLSNSSMNT----AHYKSPAFDSIMAETLKVTDEAQRTALYT 493 W A Y +P +FL++M S + P D + E L DE QR ALY Sbjct: 394 FHRTWGAPY-DPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYR 452 Query: 494 KAEQQLDKDSAIVPVYYYVNARLVKPWVGGYT 525 +L ++ +P+ Y + KP +G Sbjct: 453 DILTRLHDEAVYLPISYISMMVVSKPELGNIP 484 >4OER-A nrPDB Length = 500 Score = 351 bits (900), Expect = 5e-97, Method: Composition-based stats. Identities = 112/509 (22%), Positives = 205/509 (40%), Gaps = 52/509 (10%) Query: 40 TLVRNNGSEVQSLDPHKIEGVPESNISRDL-FEGLLVSDLDGHPAPGVAESWD-NKDAKV 97 L + V L+PH P ++++ +E L+ + DG P +AESW+ ++D + Sbjct: 3 KLNFSWPVNVGPLNPHLYS--PNQMFAQNMVYEPLVHYNADGTVGPWLAESWEASQDGRS 60 Query: 98 WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPI 157 +TF LR+D K+S+G A + + + ++ + +++++ Sbjct: 61 YTFKLREDVKFSNGEVFDAAAVKANIDTVL--------QNRPRHNWLELVNQMV------ 106 Query: 158 TDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPG--NIVTNG 215 + + + + + L +P + L P P A +F T G + G Sbjct: 107 ---SAEVVGPYKVRINLKKPYYPLLQELSLP--RPFRFIAPSQFKNGGTADGIVAPIGTG 161 Query: 216 AYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM---TNN 272 + L + + E V R+ +YW K Q+T I T + +GEID+ T Sbjct: 162 PWKLTETKLGEHDVFTRNDSYWG-PKPAYEQITVKVIPDPNTRAIAFEAGEIDLIYGTEG 220 Query: 273 SMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKV 332 + + F++ +K + L T +N D+ VR A+ +D+D ++ V Sbjct: 221 PISPDTFERFQKMGIYNTELSEPLETRVLALNTNHGATKDLAVRKAINHAVDKDTMIATV 280 Query: 333 KAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA----------D 382 A A + + A +LL EAG+TA Sbjct: 281 LYGTQKRADTLFADNVPYANIGLKPY-----AFDPALAARLLDEAGWTAKASGDIREKDG 335 Query: 383 KPLTINLLYNTSDL-HKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD-VARA 440 +PL I L + +D K +A + +K +G++VKL +E + + G FD + Sbjct: 336 QPLAIELCFIGTDAISKSMAEIVQADLRK-VGIDVKLTGEEESSIYARQRDGRFDMIFNQ 394 Query: 441 GWCADYNEPTSFLNTMLSNSSMNTAHY----KSPAFDSIMAETLKVTDEAQRTALYTKAE 496 W A Y +P +F+++M S + D+ + + L TDE R ALY Sbjct: 395 TWGAPY-DPHAFVSSMRVPSHADYQAQLGLPDKAKIDAEIGQVLVSTDETARQALYKDIL 453 Query: 497 QQLDKDSAIVPVYYYVNARLVKPWVGGYT 525 +L +++ +P+ + KP VG T Sbjct: 454 TRLHEEAVYLPLTSVTAMAVAKPEVGKIT 482 >6HLX-A nrPDB Length = 492 Score = 344 bits (883), Expect = 5e-95, Method: Composition-based stats. Identities = 116/493 (23%), Positives = 204/493 (41%), Gaps = 34/493 (6%) Query: 39 QTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAKV 97 TL E +LD G + + GL+ +DG +P +AES++ + DAK Sbjct: 2 GTLYFGLSGEPSTLDTVVQPGTSGRTVKLAIHRGLVNYGIDGKISPELAESYEVSPDAKE 61 Query: 98 WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPI 157 +TFHLR+ AK+ DGT VT+ D S +R +DP + + + L Sbjct: 62 FTFHLRQ-AKFHDGTTVTSADVKASLERILDPKGKASFRNELS----------------- 103 Query: 158 TDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAY 217 + ++ D+ T+++TLS P L P + VP A + K + V G + Sbjct: 104 SISKIETPDEKTVKLTLSTPSVAMIDYLALPESVIVPAAWLAKNADNP--NAAPVGAGPF 161 Query: 218 TLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIE 277 W I +++ Y+ K +++V Y+ + E T VN +SG++D+ + +P + Sbjct: 162 KFAGWTRGREITVKKFDDYYKKGKPDLDEVHYVFYSDENTRVNALKSGDVDIIDY-VPAK 220 Query: 278 LFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGN 337 + K ++ + + N + PF+ VR A+ +DR I+N Sbjct: 221 DAADIAKGPETQLLRNTGPF-MGLQFNTKFEPFSKPEVRQAIAYAVDRSAIINTAFNGLG 279 Query: 338 MPAYGY-TPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDL 396 P +G P G + +F E+AK LLA+AGY + + L + Sbjct: 280 SPIFGIAIPKGYMGYSDAKANYFS----HHVEKAKALLAKAGYPNGFEVRL-LATSQYSF 334 Query: 397 HKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTM 456 + AIA S K IG+ VKL +W + + G +D G + + N Sbjct: 335 QQNTAIAIQSELAK-IGIKVKLDLPDWASRMAKASTGDYDFTVMGSLGEITDADWLSNYY 393 Query: 457 LSNSSM----NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYV 512 + N+ ++ + ++ + D+A+R +Y + + S +V + Sbjct: 394 YGGDKLVRTNNSPYFNDQQINDLLDKGRATVDKAERVKIYDAFVDRALELSPLVYFMWRE 453 Query: 513 NARLVKPWVGGYT 525 VK V G+T Sbjct: 454 QNYAVKKGVTGFT 466 >5ISU-A nrPDB Length = 502 Score = 344 bits (881), Expect = 9e-95, Method: Composition-based stats. Identities = 112/527 (21%), Positives = 214/527 (40%), Gaps = 40/527 (7%) Query: 22 NVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGH 81 + A + + +L+ + + ++P+ I + ++ L ++DG Sbjct: 1 SNASSDKANGSGKAKDGGSLIIGVTGDPEVINPNYASDRVTLTIQQAVYAPLF-WEVDGK 59 Query: 82 PAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQ 140 P +A+S D + D +T L+ W DG P+TA D V++ +D SP Sbjct: 60 --PALAKSLDISDDNLTYTVKLKDGLTWHDGKPLTADDVVFTVNSILDTKQNSPNRGNFV 117 Query: 141 YGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEK 200 + + V+A+DD T++ TL P F + + P+PK E Sbjct: 118 FDD--------------KPVKVEAVDDTTVKFTLPTVAPAFENTI--KTFFPIPKHIFEG 161 Query: 201 FG--EKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTD 258 EK + N + +G Y ++ E + LER Y++ K +++VT+ + Sbjct: 162 VENIEKSDKNKNPIGSGPYKFVEYKTGEYVSLERFNDYFD-GKPKLDKVTFRITKDQNAA 220 Query: 259 VNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTA 318 ++GEI++ S+ K++K + P Y N +P +R A Sbjct: 221 NLALQNGEINL--KSIQPSDRNKVEKASAVNIITYPENRLSYATFNENQPALKSKELRQA 278 Query: 319 LKLGMDRDIIVNKVKAQ--GNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE 376 L +DR+ I++ PA + T + ++ +AKKL+ E Sbjct: 279 LSYALDREEIIDAAYGSDEYAKPASSFLTENTKYFTD-----KVETYDQDIAKAKKLVKE 333 Query: 377 AGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLV----NQEWKTFLDTRHQ 432 +G+ + LT+ L N S + +A+ + K IGV + L N LD ++ Sbjct: 334 SGFDTSQKLTVYYL-NNSKSQESIALYLQQQY-KEIGVTLDLKPTDPNALSNITLDRKNA 391 Query: 433 GTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALY 492 + +A G+ N+P ++ + LS++ N ++Y + D++ + D+ +R +Y Sbjct: 392 -DYSIALNGYIMG-NDPDAYKSLYLSDAPYNYSNYHNKDLDALWEKGAVTADDKERQEIY 449 Query: 493 TKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMY 539 K + + D+ I P+ Y + GG P T R++ Sbjct: 450 EKIQNTIADDAVIYPISYDNAVLALDSRYGGQKAATPQPVTMFRDLS 496 >1XOC-A nrPDB Length = 520 Score = 318 bits (814), Expect = 4e-87, Method: Composition-based stats. Identities = 105/526 (19%), Positives = 195/526 (37%), Gaps = 45/526 (8%) Query: 37 EKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDA- 95 + LV + E + ++I L+ L +D + +AES D Sbjct: 20 QGGDLVVGSIGEPTLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLAESIKELDGG 79 Query: 96 KVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKK 155 + ++K K+ DG +TA D V+++ + + S + Sbjct: 80 LAYDVKIKKGVKFHDGKELTADDVVFTYSVPLSKDYKGERGSTYEMLK------------ 127 Query: 156 PITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAA-----IEKFGEKWTQPGN 210 V+ D+ + L FY ST+ +PK I E Sbjct: 128 -----SVEKKGDYEVLFKLKYKDGNFYNN-ALDSTAILPKHILGNVPIADLEENEFNRKK 181 Query: 211 IVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMT 270 + +G + K+W + I LE + Y+ + ++ VTY I + ++G D+ Sbjct: 182 PIGSGPFKFKEWKQGQYIKLEANDDYF-EGRPYLDTVTYKVIPDANAAEAQLQAG--DIN 238 Query: 271 NNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVN 330 ++P ++ +K ++ D L Y N + F D +VR AL +DR+ IV+ Sbjct: 239 FFNVPATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTALDRESIVS 298 Query: 331 KVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA--------- 381 +V AY P + + E ++AK++LAEAG+ Sbjct: 299 QVLDGDGEVAYIPESPLSWN---YPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDGILDK 355 Query: 382 -DKPLTINLLYNTSD-LHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRH--QGTFDV 437 K + L N + + + +A+ KK IG+ VK EW ++ + FD Sbjct: 356 DGKKFSFTLKTNQGNKVREDIAVVVQEQLKK-IGIEVKTQIVEWSALVEQMNPPNWDFDA 414 Query: 438 ARAGWC-ADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAE 496 GW + + + ++ +N YK+ D +M + ++D Q + Y + Sbjct: 415 MVMGWSLSTFPDQYDIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQYSKEYEQIY 474 Query: 497 QQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVK 542 Q++ +D +YY N + + GY D ++ K Sbjct: 475 QKIAEDQPYTFLYYPNNHMAMPENLEGYKYHPKRDLYNIEKWWLAK 520 >4PFT-A nrPDB Length = 544 Score = 308 bits (790), Expect = 3e-84, Method: Composition-based stats. Identities = 106/499 (21%), Positives = 186/499 (37%), Gaps = 58/499 (11%) Query: 47 SEVQSLDPHKIEGVPESNISRDLFEGLLVSD-LDGHPAPGVAESWDNKDAKVWTFHLRKD 105 S + +P I ++E L + D L+ P +AE + + LRK Sbjct: 17 SPPSNWNPFTPWNAVAGTIGL-VYEPLFLYDPLNDKFEPWLAEKGEWVSNNEYVLTLRKG 75 Query: 106 AKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAI 165 +W DG P+TA D V++++ + S + G I + + Sbjct: 76 LRWQDGVPLTADDVVFTFEIAKKYTGISYSPVWNWLGRI------------------ERV 117 Query: 166 DDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKW---TQPGNIVTNGAYTLKDW 222 D+ TL+ S+P +K ++ +T VPK E E+ N V +G Y ++ W Sbjct: 118 DERTLKFVFSDPRYQEWKQML-INTPIVPKHIWENKTEEEVLQAANENPVGSGPYYVESW 176 Query: 223 VVNERIVLERSPTYWN----NAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIEL 278 ++R V +++ +W ++ L + S V GE+D +N +P Sbjct: 177 -ADDRCVFKKNGNWWGIRELGYDPKPERIVELRVLSNNVAVGMLMKGELDWSNFFLPGVP 235 Query: 279 FQKLKKEIPDEVHVDPYL---CTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQ 335 K I PY+ T IN K P + R A+ ++ + IV + Sbjct: 236 VLKKAYGIVTWYENAPYMLPANTAGIYINVNKYPLSIPEFRRAMAYAINPEKIVTRAYEN 295 Query: 336 GNMPAYGY-TPPYTDGAKLTQPEWF-GWSQEKRNEEAKKLLAEAGYT------------- 380 A P K E + + E AKK+L E G+ Sbjct: 296 MVTAANPAGILPLPGYMKYYPKEVVDKYGFKYDPEMAKKILDELGFKDVNKDGFREDPNG 355 Query: 381 ADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARA 440 LTI Y +D + A L K +G+NV+ ++ + D + G FD+ Sbjct: 356 KPFKLTIECPYGWTDWMVSIQSIAEDLVK--VGINVEPKYPDYSKYADDLYGGKFDLILN 413 Query: 441 GWCADYNEP-TSFLNTMLSNS--------SMNTAHYKSPAFDSIMAETLKVTDEAQRTAL 491 + + S+ N + S N Y +P ++++ E + D+A+ + Sbjct: 414 NFTTGVSATIWSYFNGVFYPDAVESEYSYSGNFGKYANPEVETLLDELNRSNDDAKIKEV 473 Query: 492 YTKAEQQLDKDSAIVPVYY 510 K + L KD +P++Y Sbjct: 474 VAKLSEILLKDLPFIPLWY 492 >4PFU-A nrPDB Length = 547 Score = 308 bits (789), Expect = 4e-84, Method: Composition-based stats. Identities = 101/513 (19%), Positives = 197/513 (38%), Gaps = 62/513 (12%) Query: 47 SEVQSLDPHK-IEGVPESNISRDLFEGLLVSD-LDGHPAPGVAESWDNKDAKVWTFHLRK 104 S + +P VP + ++E + D L G+ P +AE + D+K + LR+ Sbjct: 17 SPPSNWNPFTPWNAVPGTT--GLVYETMFFYDPLTGNFDPWLAEKGEWLDSKTYRVVLRE 74 Query: 105 DAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKA 164 W D P+T++D ++++ + H + + E L+ ++ Sbjct: 75 GIYWHDNVPLTSEDVRFTFEIAKKYKGI----------HYSSVWEWLD--------HIET 116 Query: 165 IDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKW---TQPGNIVTNGAYTLKD 221 D+ T+ +P + + L++ + VPK E+ E + + +G Y Sbjct: 117 PDNRTVIFVFKDPRYHEWNELLY-TLPIVPKHIWEEKDETTILQSSNEYPLGSGPYVAHS 175 Query: 222 WVVNERIVLERSPTYWNNA----KTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIE 277 W N +++ ER +W K V + + S + GE+D +N +P Sbjct: 176 WDQN-KMIFERFENWWGTKVMGVKPAPKYVVIVRVLSNNVALGMLMKGELDFSNFMLPGV 234 Query: 278 LFQKLKKEIPDEVHVDPY---LCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA 334 K + PY +N +K P + R A+ + ++ D IV +V Sbjct: 235 PILKKVYNLNTWYDEPPYHLSSTVVGLFLNARKYPLSLPEFRRAIAMSINADPIVQRVYE 294 Query: 335 QGNMPAY--GYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYT-----------A 381 + A G+ P + + EEAK +L + G+ Sbjct: 295 GAVLKADPLGFLPNSVWMKYYPKEVVEKHGFKYDPEEAKSILDKLGFRDVNGDGFRETPD 354 Query: 382 DKP--LTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDV-A 438 KP LTI Y +D + + + L K +G+N + + + + ++G FD+ Sbjct: 355 GKPIKLTIECPYGWTDWMQAIQVIVDQL--KVVGINAEPYFPDSSKYYENMYKGEFDIEM 412 Query: 439 RAGWCADYNEPTSFLNTMLSNSSM--------NTAHYKSPAFDSIMAETLKVT--DEAQR 488 A + P ++ NT+ ++ N Y++P +S++ E + + + Sbjct: 413 NANGTGISSTPWTYFNTIFYPDALESEFSYTGNYGRYQNPEVESLLEELNRTPLDNVEKV 472 Query: 489 TALYTKAEQQLDKDSAIVPVYYYVNARLVKPWV 521 T L K + L KD +P++Y A + + V Sbjct: 473 TELCGKLGEILLKDLPFIPLWYGAMAFITQDNV 505 >5YQW-A nrPDB Length = 532 Score = 307 bits (787), Expect = 7e-84, Method: Composition-based stats. Identities = 107/529 (20%), Positives = 202/529 (38%), Gaps = 70/529 (13%) Query: 36 AEKQTLVRNNG---SEVQSLDPHKIEGVPESNISRDLFEGLLVSDL--DGHPAPGVAESW 90 AE+ L + + V++ +P + + ++E L+V + P +AE++ Sbjct: 1 AERSELTIHPKEFTTFVRNFNPFLGATNLHTT-TDFIYEPLVVFNEMHGNTPVFRLAENF 59 Query: 91 D-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDE 149 + D TF +RK KWSDG TA D VYS+ + E Sbjct: 60 QMSDDLMSVTFDIRKGVKWSDGEAFTADDVVYSFNLVKEK------------------PE 101 Query: 150 ILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT-QP 208 + + GV+ ++D+ ++ LSE + VPK K + T Sbjct: 102 LDQSGINSWVTGVEKVNDYQVKFRLSEANSNVPYEIA--KVPVVPKHVWSKVKDPSTFTN 159 Query: 209 GNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEID 268 N V +G +T+ D + + +P YW+ A ++ + IA+ + + +GE+D Sbjct: 160 ENPVGSGPFTVIDTFTPQLYIQCENPNYWDAANLDVDCLRVPQIANNDQFLGKVVNGEMD 219 Query: 269 MTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP------PFNDVRVRTALKLG 322 T++ +P ++ + P + P T + +N + P +V R A + Sbjct: 220 WTSSFVP-DIDRTYAAASPKHHYWYPPAGTQAFVVNFKNPDAAKNEALTNVDFRRAFSMA 278 Query: 323 MDRDIIVNKVKAQGNMP---AYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGY 379 +DR I++ G A G + + + F E AKKLLA+AG+ Sbjct: 279 LDRQTIIDIAFYGGGTVNDFASGLGYAFEAWSDEKTHDKFKAYNSYNAEGAKKLLAKAGF 338 Query: 380 T-------------ADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTF 426 L I +D + + +A L +G+ + ++ + Sbjct: 339 KDVNKDGFVDTPSGKSFELLIQSPNGWTDFNNTVQLAVEQLA--EVGIKARARTPDFSVY 396 Query: 427 LDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTA---------HYKSPAFDSIMA 477 +GT+DVA + +P ++ N+ NS++ + YK+ D ++ Sbjct: 397 NQAMLEGTYDVAYTNYFHG-ADPYTYWNSAY-NSALQSGDGMPRFAMHFYKNEKLDGLLN 454 Query: 478 ETLKVTDEAQRTALYTKAEQQLDKDSAIVPV------YYYVNARLVKPW 520 K D+ ++ + +Q + +D +PV Y Y R W Sbjct: 455 SFYKTADKQEQLEIAHGIQQIIAQDQVTIPVLSGAYMYQYNTTRFTGWW 503 >1ZTY-A nrPDB Length = 529 Score = 305 bits (780), Expect = 5e-83, Method: Composition-based stats. Identities = 102/516 (19%), Positives = 199/516 (38%), Gaps = 74/516 (14%) Query: 49 VQSLDPHKIEGVPESNISRDLFEGLLVSDL--DGHPAPGVAESWDNKDAK-VWTFHLRKD 105 V++ +P+ + + ++E L+V + P +AES+ D TF +RK Sbjct: 15 VRNFNPYLATNL--RTTTDFIYEPLVVFNEMKGNTPVFRLAESYKMADDLMSVTFDIRKG 72 Query: 106 AKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAI 165 KWSDG TA D VYS+ G + E+ + V+ + Sbjct: 73 VKWSDGEAFTADDVVYSF------------------GLLKAKPELDQRGINKWVTSVEKV 114 Query: 166 DDHTLEVTLSEP---VPYFYKLLVHPSTSPVPKAAIEKFGEKWT-QPGNIVTNGAYTLKD 221 D++ + LSE VPY L+ V + + + T N V G +T+ D Sbjct: 115 DEYKVRFRLSEANSNVPYEISLI-----PIVAEHVWKDVKDPTTFTNENPVGTGPFTVID 169 Query: 222 WVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQK 281 + + R+P YW+ A ++ + IA+ + + + E+D T++ +P ++ + Sbjct: 170 TFTPQLYIQCRNPNYWDAANLEVDCLRVPQIANNDQLLGKIVNSELDWTSSFVP-DIDRT 228 Query: 282 LKKEIPDEVHVDPYLCTYYYEINNQKP------PFNDVRVRTALKLGMDRDIIVNKVKAQ 335 P+ + P T + +N + P ++V R A + +DR I++ Sbjct: 229 YAAANPNHHYWYPAAGTQAFMVNFKNPDPAKKEALDNVDFRRAFSMALDRQTIIDIAFYG 288 Query: 336 GNMP---AYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYT------------ 380 A G + + + + E +KKLLA+AG+ Sbjct: 289 SGTVNDFASGLGYAFEAWSDEATHKKYKGFNTYDVEGSKKLLAKAGFKDVNGDGFVETPS 348 Query: 381 -ADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVAR 439 L I +D + + +A L + +G+ K E+ + +GT+DVA Sbjct: 349 GKSFELLIQSPNGWTDFNNTVQLAVEQL--QEVGIKAKARTPEFAVYNQAMLEGTYDVAY 406 Query: 440 AGWCADYNEPTSFLNTMLSNSSMNTA---------HYKSPAFDSIMAETLKVTDEAQRTA 490 + +P ++ N+ NS++ + ++ D ++ K D+ ++ A Sbjct: 407 TNYFHG-ADPFTYWNSGY-NSALQSGDGMPRFAMHYFTDKKLDGLLDSFYKTADKNEQLA 464 Query: 491 LYTKAEQQLDKDSAIVPV------YYYVNARLVKPW 520 + ++ + ++ +PV Y Y R W Sbjct: 465 IAHGIQKIIAENQVTIPVMSGAWMYQYNTTRFTGWW 500 >5YH8-A nrPDB Length = 510 Score = 295 bits (756), Expect = 3e-80, Method: Composition-based stats. Identities = 98/513 (19%), Positives = 188/513 (36%), Gaps = 56/513 (10%) Query: 33 VTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD- 91 E + L ++ ++PH G + ++E L+ + DG P +A+ WD Sbjct: 6 EEKKENKQLTYTTVKDIGDMNPHVYGG--SMSAESMIYEPLVRNTKDG-IKPLLAKKWDV 62 Query: 92 NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEIL 151 ++D K +TFHLR D K+ DGTP A + + + Sbjct: 63 SEDGKTYTFHLRDDVKFHDGTPFDADAVKKNIDAVQENKKLHSW---------------- 106 Query: 152 EGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPG-- 209 K VK D +T+E+ L E L P P + + F T+ G Sbjct: 107 -LKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMP--RPYVFVSPKDFKNGTTKDGVK 163 Query: 210 NIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEI-- 267 G + L + +E ++ YW K+ +N+V + + T + GE Sbjct: 164 KFDGTGPFKLGEHKKDESADFNKNDQYWGE-KSKLNKVQAKVMPAGETAFLSMKKGETNF 222 Query: 268 ----DMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKP--PFNDVRVRTALKL 321 D +S+ + ++LK +V + T +N+ K +D VR A+ Sbjct: 223 AFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGH 282 Query: 322 GMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA 381 ++RD I ++ PA P +++ ++A+ LL EAG+ Sbjct: 283 MVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMP-----TRKYDLKKAESLLDEAGWKK 337 Query: 382 DKP----------LTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRH 431 K L + + Y+ +K K +G+ + + + + R Sbjct: 338 GKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRT 397 Query: 432 QGTFDVA-RAGWCADYNEPTSFLNTMLSNSSMNTA----HYKSPAFDSIMAETLKVTDEA 486 G +D+ W Y +P S + + + +A K ++S + + K+ + Sbjct: 398 SGDYDLMFNQTWGLLY-DPQSTIAAFKAKNGYESATSGIENKDKIYNS-IDDAFKIQNGK 455 Query: 487 QRTALYTKAEQQLDKDSAIVPVYYYVNARLVKP 519 +R+ Y +Q+D + +P+ + + Sbjct: 456 ERSDAYKNILKQIDDEGIFIPISHGSMTVVAPK 488 >4OEU-A nrPDB Length = 494 Score = 292 bits (747), Expect = 3e-79, Method: Composition-based stats. Identities = 102/523 (19%), Positives = 191/523 (36%), Gaps = 57/523 (10%) Query: 38 KQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAK 96 K TL+ +E+ ++P E + +F GL D + P +A+SWD +KD Sbjct: 4 KDTLIIAVENEIARINPAYSED--HDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGL 61 Query: 97 VWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKP 156 V+ LR D W DG +A D +S + +P S + Y+ + I Sbjct: 62 VYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNS--SIYVNFEDIKS---------- 109 Query: 157 ITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFG-EKWTQPGNIVTNG 215 V+ ++ +++TL +P P F L S +PK +E + N + G Sbjct: 110 -----VEILNPSHVKITLFKPYPAFLDAL---SIGMLPKHLLENENLNTSSFNQNPIGTG 161 Query: 216 AYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMP 275 Y W E + + + ++ K ++ I ++G+ID + Sbjct: 162 PYKFVKWKKGEYVEFKANEHFY-LDKVKTPRLIIKHIFDPSIASAELKNGKIDAA--LID 218 Query: 276 IELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQ 335 + L K + + + N D++VR AL +D++ IV + Sbjct: 219 VSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHD 278 Query: 336 GNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKP---------LT 386 Y + + + F + ++A+ LL AG+ +K L Sbjct: 279 -----YAFVANHPLERSWANSKNFK-IYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILE 332 Query: 387 INLLYNTSD-LHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCAD 445 + ++D L LA S ++K IGV K+V + +F D GW + Sbjct: 333 FEIWAMSNDPLRVSLAGILQSEFRK-IGVVSKVVAKPAGSF----DYSKVDSFLIGWGSP 387 Query: 446 Y-NEPTSF------LNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQ 498 + +F ++ L++ N HY D + + ++ +R Y Sbjct: 388 LDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDA 447 Query: 499 LDKDSAIVPVYYYVNARLVKPWVGGYTGKD--PLDNTYTRNMY 539 L ++ + + Y A + + G + +T N+Y Sbjct: 448 LYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVY 490 >3I5O-A nrPDB Length = 592 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 110/526 (20%), Positives = 197/526 (37%), Gaps = 77/526 (14%) Query: 59 GVPESNISRDLFEGLLVSDLDG---HPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVT 115 P+S D F L D P +AE ++ D K ++R +A+WSDG P+T Sbjct: 27 YAPQSTWGTDQFMYLPAFQYDLGRDAWIPVIAERYEFVDDKTLRIYIRPEARWSDGVPIT 86 Query: 116 AQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLS 175 A DFVY+ + + + L G G D +E VKA+D +E Sbjct: 87 ADDFVYALELTKE----------LGIGPGGGWDTYIE--------YVKAVDTKVVEFKAK 128 Query: 176 EP-VPYFYKLLVHPSTSPVPKAAIEKFGEKW-------TQPGNIVTNGAYTLKDWVVNER 227 E + YF L P+PK E+ + +P V +G Y L + N Sbjct: 129 EENLNYFQFLSYSLGAQPMPKHVYERIRAQMNIKDWINDKPEEQVVSGPYKLYYYDPN-I 187 Query: 228 IVLERSPTYWNN---AKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMP--IELFQKL 282 +V +R +W + ++ + + G+ID +P EL++K Sbjct: 188 VVYQRVDDWWGKDIFGLPRPKYLAHVIYKDNPSASLAFERGDIDWNGLFIPSVWELWEKK 247 Query: 283 KKEIPDEVHVDPYL---CTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMP 339 + +PY + +NN KP +D VR A+ + + ++ K Sbjct: 248 GLPVGTWYKKEPYFIPDGVGFVYVNNTKPGLSDPAVRKAIAYAIPYNEMLKKAYFGYGSQ 307 Query: 340 AYG-----YTPPYTDGAKLTQPEWFGWSQEKRN----EEAKKLLAEAGYTAD-------- 382 A+ PY + +++ R + A K+L EAGY Sbjct: 308 AHPSMVIDLFEPYKQYIDYELAKKTFGTEDGRIPFDLDMANKILDEAGYKKGPDGVRVGP 367 Query: 383 -----KPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDV 437 P TI++ Y +D + A +L ++IG++VK ++ + D +GTFD+ Sbjct: 368 DGTKLGPYTISVPYGWTDWMMMCEMIAKNL--RSIGIDVKTEFPDFSVWADRMTKGTFDL 425 Query: 438 ARAGW--CADYNEPTSFLNTMLSNS----------SMNTAHYKSPAFDSIMAETLKVTDE 485 W ++ P + +L + + Y + ++ + + D Sbjct: 426 II-SWSVGPSFDHPFNIYRFVLDKRLSKPVGEVTWAGDWERYDNDEVVELLDKAVSTLDP 484 Query: 486 AQRTALYTKAEQQLDKDSAIVPVYYYVNA--RLVKPWVGGYTGKDP 529 R Y + +Q + +D +P +Y + K W+ + +P Sbjct: 485 EVRKQAYFRIQQIIYRDMPSIPAFYTAHWYEYSTKYWINWPSEDNP 530 >3T66-A nrPDB Length = 496 Score = 285 bits (730), Expect = 3e-77, Method: Composition-based stats. Identities = 118/530 (22%), Positives = 199/530 (37%), Gaps = 60/530 (11%) Query: 30 PAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDG-HPAPGVAE 88 + A ++ + SLDPH + + + E L+ D + AP +AE Sbjct: 4 SSSNEGAGEKHIHFLFNVSTNSLDPH--VDMTYIPVRAGITETLVRVDEENVTIAPWLAE 61 Query: 89 SWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGID 148 SWD+ D + WT LR+D + +G + A+ S +R++D + A A ID Sbjct: 62 SWDSTDGQHWTIKLREDVTFQNGKEMDAEAVKASLERALDESVAIENAL--------KID 113 Query: 149 EILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQP 208 EI D +TL +T EP P F LV+P+ S I+ E +T Sbjct: 114 EIEA-------------DGYTLHITTKEPFPEFISELVNPNVSI-----IDVTEEDFT-- 153 Query: 209 GNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEID 268 + V G + L+ + ++ L R YW+ A ++ VT+ SG+ D Sbjct: 154 NHPVGTGPFALESFTPGSKLELVRYDEYWDGAS-KLDSVTFSFNEDASARSLALESGQAD 212 Query: 269 MTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDII 328 + +E + L+ V T+ +N + DV VR A+ + +DR I Sbjct: 213 IVYRP-EVESIETLQANEGIMVEATETFRTHNLTMNLDRDSLKDVNVRRAVDVLLDRQEI 271 Query: 329 VNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADK----- 383 V+ + A G P A + + G + A + L EAGYT + Sbjct: 272 VDTIMLGYAEVADGPFIPTLPFAPSYEKKETG------TDIAIQYLEEAGYTLENGQMQK 325 Query: 384 ---PLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEW-KTFLDTRHQGTFDVAR 439 PL +L S L K IG+ V++ E + ++ + + Sbjct: 326 DGEPLHFTVLTYGSRAELPLIAQVFQSNAKQIGIEVEIRQIEVPEEYMASNRDWDL-ITY 384 Query: 440 AGWCADYNEPTSFLN-TMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQ 498 + + + +LN T ++N + P I+ E + D+ R L +A Sbjct: 385 SNVTSPRGDAGYYLNATYHPTGALNFSSVNDPELTGIIDELNRTVDQDVRAKLTEQAAAY 444 Query: 499 LDKDSAIVPVYYYVNARL-----VKPWVGG----YTGKDPLDNTYTRNMY 539 +D+ + + VK WV Y + LD N+Y Sbjct: 445 IDEQKIHSFLIHPSAVVAYDENKVKNWVTTRSEYYMITNQLDVNA-ENLY 493 >5ZA4-A nrPDB Length = 488 Score = 278 bits (712), Expect = 3e-75, Method: Composition-based stats. Identities = 114/501 (22%), Positives = 190/501 (37%), Gaps = 63/501 (12%) Query: 52 LDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPG------VAESWDNKDAKVWTFHLRKD 105 DP G + +FEGL+ D HP A+ + KD + LR+ Sbjct: 22 FDPLTSSGASSMAANLHIFEGLV----DLHPVTRQPYLALAAKEPEQKDDLTYYISLREG 77 Query: 106 AKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAI 165 A + DG+PVT +D VYS++R +DP AS +A ++ + V A+ Sbjct: 78 AMFHDGSPVTTEDVVYSFERVLDPAKASLFAQFIPF-----------------IASVTAL 120 Query: 166 DDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVN 225 DD+ +E L P F + L VPK +E + + +G Y + Sbjct: 121 DDNVVEFKLKYPFALFKERLTI--IKIVPKHIVE--AGQSAFDAKPIGSGPYKFVSATKD 176 Query: 226 ERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKE 285 +RIV E + Y + + ++T+ ++ + V SG + S+P ++LK+ Sbjct: 177 DRIVFEANTVYNGHYPAKVEKMTWFLLSDDAARVTAQESGRVQAIE-SVPYLDAERLKR- 234 Query: 286 IPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTP 345 + V + N +K PF++ +VR AL +D+ +++ V A Y Sbjct: 235 -KNNVESVQSFGLLFLMFNCEKAPFDNPKVRQALHYALDKQKLIDIVFLGNAKAATSYL- 292 Query: 346 PYTDGAKLTQPEWFGWSQEKRNEEAK--KLLAEAGYTADKPLTINLLYNTSDLHKKLAIA 403 + T P++ S + ++AK KLLAEAG T LT LL K+ A Sbjct: 293 ------QDTHPDYVKASSQYDYDKAKAEKLLAEAGITN---LTFQLLATDHAWVKECAPL 343 Query: 404 ASSLWKKNIGVNVKLVNQEWKTFLDT-RHQGTFDVARAGWCADY--NEPTSFLNTMLSNS 460 W V V L + + +G ++V A N+ L+ Sbjct: 344 ILESWNALSVVKVTLQHLQSGALYSAHVDKGAYEVVIAPGDPSVFGNDLDLLLSWWYRGD 403 Query: 461 SM--------NTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYV 512 NTA Y ++ E +K + A + KA + + + P+ + Sbjct: 404 VWPKRRFRWANTAEYH--EVQKLLDEAIK--NPAGSKVAWQKAINIIAEQVPLYPIIHRK 459 Query: 513 NARLVKPWVGGYTGKDPLDNT 533 T PL T Sbjct: 460 --LPTAWNTKKLTDFQPLPTT 478 >4ZE8-A nrPDB Length = 499 Score = 277 bits (708), Expect = 1e-74, Method: Composition-based stats. Identities = 109/501 (21%), Positives = 194/501 (38%), Gaps = 41/501 (8%) Query: 35 LAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSD--LDGHP------APGV 86 + E++ L SL+P I +F+ L+ D G P P + Sbjct: 1 MQERRALRLGVNGLPNSLEPVNAISNVGPRIVNQIFDTLIARDFFAKGAPGNAIDLVPAL 60 Query: 87 AESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 AESW+ D K F LR+ + DG +TA D Y++ +S +G Sbjct: 61 AESWERIDEKSVRFKLRQKVMFHDGVELTADDVAYTF------------SSERLWGP-EA 107 Query: 147 IDEILEGKKPITDLGVKAI-DDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKW 205 I +I GK D + D +T+ + P + + VPK +K G Sbjct: 108 IKKIPLGKSYSLDFDEPVVEDKYTVTLRTKTPSYLIETFVASWMSRIVPKEYYKKLGA-V 166 Query: 206 TQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSG 265 V G Y ++V +R+VLE + YW K +++TY +A T V SG Sbjct: 167 DFGNKPVGTGPYKFVEFVAGDRVVLEANDAYWG-PKPTASKITYQIVAEPATRVAGLISG 225 Query: 266 EIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYY-YEINNQKPPFNDVRVRTALKLGMD 324 E D+ P ++ +L PD + ++ + N + F D ++R AL L ++ Sbjct: 226 EYDIITTLTPDDI--QLINSYPDLETRGTLIENFHMFTFNMNQEVFKDKKLRRALALAVN 283 Query: 325 RDIIVNKV-KAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADK 383 R I+V + K Q ++PA P Y + + + E EEAK+L+ E+GY Sbjct: 284 RPIMVEALWKKQASIPAGFNFPNYGETFDPKRK-----AMEYNVEEAKRLVKESGYD-GT 337 Query: 384 PLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWC 443 P+T + + N + +WK+ IGVNV + +F + + W Sbjct: 338 PITYHTMGNYYANAMPALMMMIEMWKQ-IGVNVVMKTYAPGSFPPDNQTWMRNWSNGQW- 395 Query: 444 ADYNEPTSFLNTMLSNSSMNTAHYKSP---AFDSIMAETLKVTDEAQRTALYTKAEQQLD 500 + + + + + F+ + + + + +R Y + + Sbjct: 396 --MTDAYATIVPEFGPNGQVQKRWGWKAPAEFNELCQKVTVLPNGKERFDAYNRMRDIFE 453 Query: 501 KDSAIVPVYYYVNARLVKPWV 521 +++ V +Y + + V Sbjct: 454 EEAPAVILYQPYDVYAARKDV 474 >2WOP-A nrPDB Length = 562 Score = 271 bits (693), Expect = 4e-73, Method: Composition-based stats. Identities = 116/527 (22%), Positives = 207/527 (39%), Gaps = 58/527 (11%) Query: 38 KQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLD-----GHPAPGVAESWD- 91 TL + ++V SLDP + V + R L L+ D PAP +AE Sbjct: 32 GGTLRLVSSADVDSLDPARTYYVWVWLLQRLLNRTLMAYPTDPGPAGLVPAPDLAEGPGE 91 Query: 92 -NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEI 150 + + WT+ LR+ ++ DGTP+T+ D ++ QR + +YL + E Sbjct: 92 VSDGGRTWTYRLRRGLRYDDGTPITSDDVRHAVQRVFAQDVLPGGPTYLI--PLLDDPER 149 Query: 151 LEGKKPITDLGVKAI---DDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQ 207 TD ++++ D+HT+ L+ P F L+ P +PVP+ G + + Sbjct: 150 PYPGPYRTDEPLRSVLTPDEHTIVFRLTRPFSDFDHLMAQPCAAPVPRR--SDTGADYGR 207 Query: 208 PGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVI-----NQVTYLPIASEVTDVNRY 262 ++G Y + + + LER+P +W+ A I ++V R Sbjct: 208 D--PRSSGPYRVARHEPDTLLHLERNP-HWDRATDPIRPALPDRVELTIGLDVDVLDARL 264 Query: 263 RSGEIDMTNNSMPIELFQKLKKEIPDEV---HVDPYLCTYYYEINNQK--PPFNDVRVRT 317 +GE D+ ++ + ++ DEV H D ++ + + Q PPF++V VR Sbjct: 265 IAGEFDINLEGRGLQHAAQ-RRATADEVLRSHTDNPRTSFLHFVAMQPHIPPFDNVHVRR 323 Query: 318 ALKLGMDRDIIVNK---VKAQGNMPAYGYTPPYTDGAK----LTQPEWFGWSQEKRNEEA 370 A++ D+ ++ + G++ + P T P+ G R E A Sbjct: 324 AVQYAADKILLQDARGGPVNGGDLTTALFPPTLPAHQDLDLYPTGPDLRGDLDAARAELA 383 Query: 371 KKLLAEAGYTADKPLTINLLYNTSDLHKKLAI--AASSLWKKNIGVNVKLVNQEWKTFLD 428 L + G+ A + T +L SL + I + VK ++ L Sbjct: 384 AAGLPD-GFRA--------VIGTQRGKFRLVADAVVESLARVGIELTVKELDVATYFSLG 434 Query: 429 TRHQGTFDVARAG-----WCADYNEPTSFLNTMLSNS-------SMNTAHYKSPAFDSIM 476 H T G W AD+ FL ++ + N P ++++ Sbjct: 435 AGHPETVREHGLGLLVTDWGADFPTEYGFLAPLVDGRQIKRNGGNWNLPELDDPEVNALI 494 Query: 477 AETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGG 523 ETL TD A R L+ E+++ + + ++P+ + PWV Sbjct: 495 DETLHTTDPAARAELWRAVERRVMEHAVLLPLVHDKTLHFRNPWVTN 541 >4OFL-A nrPDB Length = 499 Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats. Identities = 96/482 (19%), Positives = 180/482 (37%), Gaps = 69/482 (14%) Query: 40 TLVRNNGSEVQS-LDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD-NKDAKV 97 TL G E DP G + L LL + D + + + D K Sbjct: 4 TLQLAIGDEPTEGFDPML--GWSHGSYLL-LHSPLLKQNEDFSWDSLLLSQYQPSDDGKT 60 Query: 98 WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPI 157 W L+ D K+SDG+P+TA+D +++ N A+ + G+ Sbjct: 61 WLLTLKPDLKFSDGSPLTAKDVAFTY------NNAAASGGKVDMGNF------------- 101 Query: 158 TDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAY 217 L + ID + + L P F +L K + + +K + G Y Sbjct: 102 --LSAEVIDPLNVRIHLKAPQSTFVNVLGSLGIVSADKYNAKTYAQK------PIGAGPY 153 Query: 218 TLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM--TNNSMP 275 L + +++++E +P Y N K +++ + E + +SG++ + SM Sbjct: 154 RLVSFQPGQQMIVEANPYYAGN-KNDFDKLIF-VFLDEDSAFAAAQSGQLGVVRIPPSMA 211 Query: 276 IELFQKLKKEIPDEVH-------VDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDII 328 + +K + V P + DV +R A+ ++R ++ Sbjct: 212 VGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTADVAIRRAINYAINRQLL 271 Query: 329 VNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGY--------- 379 +++ +PAY G P+ ++ ++AK++L +AG+ Sbjct: 272 ADQIMEGHAIPAY----TGVQGLPWNNPD--SAIKDGDIDKAKQILEQAGWQLNSQGTRE 325 Query: 380 TADKPLTINLLYNTSDLHKK-LAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVA 438 P I L Y + D ++ LA A S+ K IG++V L + W+T H + Sbjct: 326 KNGLPAKITLWYTSGDTTRRDLAQALRSML-KPIGIDVDLKSGSWETVERNMHA---NPT 381 Query: 439 RAGWCADYNEPTSFLNTMLSNSS----MNTAHYKSPAFDSIMAETLKVTDEAQRTALYTK 494 GW + +P + SN++ N +YK+P D + + L Q + + Sbjct: 382 LFGWGS--LDPMELYHHYSSNAAGVEYYNPGYYKNPMVDKHLQQALDAPTWQQAVPFWQQ 439 Query: 495 AE 496 + Sbjct: 440 VD 441 >3DRH-A nrPDB Length = 590 Score = 246 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 109/501 (21%), Positives = 198/501 (39%), Gaps = 58/501 (11%) Query: 71 EGLLVSDLDGHPAPG-VAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDP 129 +GL +D G A+ +K++K T LRKD KWSDG+ VTA+D+ ++++ +P Sbjct: 70 DGLFFTDSGFKFIKGGAADVALDKESKTATITLRKDLKWSDGSEVTAKDYEFTYETIANP 129 Query: 130 NTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAID---DHTLEVTLSEPVP------- 179 S + +I G+ + GK G+ D ++V E P Sbjct: 130 AYGSDRWT-DSLANIVGLSDYHTGKAKTIS-GITFPDGENGKVIKVQFKEMKPGMTQSGN 187 Query: 180 -YFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWN 238 YF + + + A + + G + ++ V E I +P YW Sbjct: 188 GYFLETVA--PYQYLKDVAPKDLASSPKTTTKPLVTGPFKPENVVAGESIKYVPNPYYWG 245 Query: 239 NAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEV--HVDPYL 296 K +N +TY + S V S + D+ N + ++++K +V Y+ Sbjct: 246 E-KPKLNSITYEVV-STAKSVAALSSSKYDIINGMVS-SQYKQVKNLKGYKVLGQQAMYI 302 Query: 297 CTYYYEI-----------NNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTP 345 YY + ++K P D VR A+ + + NK + PA P Sbjct: 303 SLMYYNLGHYDAKNSINVQDRKTPLQDQNVRQAIGYARNVAEVDNKFSNGLSTPANSLIP 362 Query: 346 PYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPL--------TINLLY--NTSD 395 P + T G+ ++ ++A KLL E G+ +K ++L+Y D Sbjct: 363 PI--FKQFTSSSVKGYEKQ-DLDKANKLLDEDGWKLNKSTGYREKDGKELSLVYAARVGD 419 Query: 396 LH-KKLAIAASSLWKKNIGVNVKLVN---QEWKTFLDTRH----QGTFDVARAGWCADYN 447 + + +A WKK IGV V L N E+ +++D +D+ W + Sbjct: 420 ANAETIAQNYIQQWKK-IGVKVSLYNGKLMEFNSWVDHMTTPPGANDWDITDGSWSL-AS 477 Query: 448 EPTSFLNTMLSNSSMNTAHYKSPAFDSIMA--ETLKVTDEAQRTALYTKAEQQLDKDSAI 505 EP+ + + + N H+ + ++ K + R A + K ++ ++K + + Sbjct: 478 EPSQ-QDLFSAAAPYNFGHFNDSEITKDLNDIDSAKSENPTYRKAAFVKYQEDMNKKAYV 536 Query: 506 VPVYYYVNARLVKPWVGGYTG 526 +P + +N V V G T Sbjct: 537 IPTNFMLNYTPVNKRVVGMTL 557 >2D5W-A nrPDB Length = 603 Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats. Identities = 109/595 (18%), Positives = 199/595 (33%), Gaps = 128/595 (21%) Query: 37 EKQTLVRNNGSEV----QSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVA-ESWD 91 + +LV E +S I + LF + + D P +A E Sbjct: 4 QDNSLVIGASQEPRVLAGDFLRVISNQAIKSEIEQYLFAPFIGFNADSQNFPVLATEVPT 63 Query: 92 NKDAK-------------VWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASY 138 ++ + +R DAKWSDG P+T +D + ++ Sbjct: 64 LENGRLRVTDIGGGKKRLEMDITIRPDAKWSDGRPITTEDVAFYFE-------------- 109 Query: 139 LQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFY----------KLLVHP 188 G G+ + ++ +K + TL EP Y+ K ++ P Sbjct: 110 --VGKAKGMPVLNPDFWERVNVRIKDARNFTLIF---EPAYYYDTYGPINTYAPKHIMGP 164 Query: 189 STSPV--------PKAAIEKFGEKW------------TQPGNIVTNGAYTLKDWVVNERI 228 V P EK E + G +V +G + LK WV I Sbjct: 165 EWERVKAAARGLDPDKDAEKLNELYRNFFLKFATPQALNRGAMVYSGPFKLKRWVPGNSI 224 Query: 229 VLERSPTY----WNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQ---- 280 +ER+P + + +V Y I + + + G ID T+ S+ + Q Sbjct: 225 EMERNPNFPIKPEGGESKYVQKVVYRFIQNTNSLLVAVIGGSIDATS-SVSLTFDQGRSP 283 Query: 281 KLKKEIPDEVH--VDPYLCTYYYEIN-------NQKPPFNDVRVRTALKLGMDRDIIVNK 331 +L + P P + +IN + ND R R A+ ++R+ +V Sbjct: 284 QLVRRAPGRFDIWFVPGAIWEHIDINKFENCQVVKDLGLNDKRTRQAILHALNREGLVKA 343 Query: 332 VKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA--DKPLTINL 389 A+ + P L P + E ++A+ LLAE G+ D L + Sbjct: 344 FFDGLQPVAHTWIAPVN---PLFNPNVKKY--EFDLKKAEALLAEMGWRKGPDGILQRTV 398 Query: 390 LYNTSDLHKKLAIAASSLWK-----------KNIGVNVKLVNQEWKTFL---------DT 429 T + A ++ + K IG+ VK+ N + Sbjct: 399 NGRTVRFEIEYVTTAGNVVRERTQQFFAEDLKKIGIAVKINNAPSAVVFADEFIQRASEC 458 Query: 430 RHQGTFDVARAGWCADYNEPTSFLNTMLSNSS-------------MNTAHYKSPAFDSIM 476 + G F+ A W ++ E S N+ N +++ FD + Sbjct: 459 KWTGMFEFA---WVSNLQEDGSLFQYKNLNTGAIMVPTKENNYQGQNIGGWRNDEFDRLT 515 Query: 477 AETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLD 531 ++ + D +R L+ +A++ ++ +P+Y+ N +V+ + Y Sbjct: 516 SQAVLEFDPERRKQLFWRAQEIWAEELPALPLYFRANPYVVRKGLVNYVASAYSG 570 >5ICQ-A nrPDB Length = 610 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 100/536 (18%), Positives = 186/536 (34%), Gaps = 85/536 (15%) Query: 36 AEKQTLVRNNGSEVQSLDPHKI-EGVPESNISRDLFEGLLVSDLDGHPA--PGVAESWDN 92 + L SL+P + G + ++F+GL+ D P +A+S D Sbjct: 61 KKGGRLRVGLPGTFDSLNPFNVKSGTAAQGLVGNVFQGLMARSQDEPFTLYPLIAQSIDI 120 Query: 93 KDAKV-WTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEIL 151 A+ TFHL A +SDG P+TA+D ++S+ + YG + Sbjct: 121 DPARTRVTFHLDPRAHFSDGKPITAEDVLFSFDLLKAKGRP---QQRIAYGLVKSA---- 173 Query: 152 EGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNI 211 A D H + L+ L++ +PK A++ Sbjct: 174 -----------TAPDPHRVAYDLTGVGDRELPLILAI-MPVLPKHALDVERFSDATLAKP 221 Query: 212 VTNGAYTLKDWVVNERIVLERSPTYWNNAKTV------INQVTYLPIASEVTDVNRYRSG 265 + +G Y + D R++L+R P YW +++ + +++G Sbjct: 222 LGSGPYVVADVQAGARLLLKRDPNYWGADIPSQRGFYNFDEIDLQYFRDGNSLFEAFKAG 281 Query: 266 EIDM----------TNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRV 315 ID T P ++ +E + + + N ++ F D R+ Sbjct: 282 LIDYRDETSTTRWSTGYDFPALRDGRMARES---LKNENPKGLNGFVFNTRRALFKDARL 338 Query: 316 RTALKLGMDRDIIVNKVKAQGNMPAYGY--------------------TPPYTDGA---- 351 R A + D + + A + P+ D Sbjct: 339 REAFGMMFDFEWVNANYYAGLYTRTKSFFDESELSSSGRGASEKERALLAPWPDAVRAEI 398 Query: 352 ---KLTQPEWFGWSQEKR-NEEAKKLLAEAGYTAD--------KPLTINLLYNTSDLHKK 399 + P G +++ A LLA AG D +P + ++ D ++ Sbjct: 399 LEGEWRPPVSDGSGRDRDMARRALDLLAAAGCRVDGDRLMKDGEPFSFEIMVKDRD-QER 457 Query: 400 LAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY---NEPTSFLNTM 456 LA+A +S + IGV V++ + + R + FD+ + A NE ++ Sbjct: 458 LALAYASSLAR-IGVEVRVRLVDEVQYQRRRQKFDFDMMIGQYVASASPGNEQRMRWSSA 516 Query: 457 LSN--SSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYY 510 +N SS N A SPA D +++ L + ++ L +VP+++ Sbjct: 517 TANQESSFNLAGAASPAIDGMISALLSARSQEDFVTAVRAYDRVLLSGFYVVPLFH 572 >5IPW-A nrPDB Length = 633 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 104/429 (24%), Positives = 161/429 (37%), Gaps = 88/429 (20%) Query: 80 GHPAPGVAESWDN-KDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASY 138 G PG+A+SW+ ++ +V+ FHLRK KWSDG P TA D V+ Sbjct: 92 GKLVPGLAKSWEVLENGRVYIFHLRKGVKWSDGAPYTAHDIVF----------------- 134 Query: 139 LQYGHIAGIDEILEGKKPITDLGVK--AIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKA 196 I G D+I K ++GVK A+DD+T++ S+P F + + + P Sbjct: 135 -WVNDIVGNDDITPSKPDWYNIGVKVEALDDYTVKFEFSKPYGLFLLKVPYGGFTGAPAH 193 Query: 197 AIEKFGEKWT----------------------------QPGNIVTNGAYTLKDWVVNERI 228 +++F K+T + + T + + Sbjct: 194 YLKQFHPKYTPMEEIEKKMVEGVHNTWVDLFNDKNDFLENTELPTLSPWKPITDPTEQFY 253 Query: 229 VLERSPTYW-----NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMT------------N 271 +LER+P +W N I+ V + + ++ + + SGEIDM N Sbjct: 254 ILERNPYFWAVDIEGNQLPYIDYVRHEYVKNDEVILLKAISGEIDMQWRHIGGLGAGAGN 313 Query: 272 NSMPIELFQ----KLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDI 327 ++ +E Q ++ K I Y + + FNDVR R AL L ++R+ Sbjct: 314 FTLLMENSQSGGYRVLKWIAANGSASRISLNYAHSDEVLRKVFNDVRFRQALSLAINREE 373 Query: 328 IVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTAD----- 382 I + P G+ PEW E + A KLL E G D Sbjct: 374 INEILFNGLAEP---RQASLVSGSPYFDPEWEKAYAEYDPDRANKLLDEMGLKWDDKHEY 430 Query: 383 ------KPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD 436 +PL + T H + WK+ IGV V++ N E F + G FD Sbjct: 431 RLLPDGRPLRFTITV-TGQFHVDVWTMVKEYWKQ-IGVWVEIENLERSLFYERADAGDFD 488 Query: 437 VARAGWCAD 445 W D Sbjct: 489 AMV--WNMD 495 >4XKN-A nrPDB Length = 473 Score = 231 bits (589), Expect = 6e-61, Method: Composition-based stats. Identities = 92/501 (18%), Positives = 171/501 (34%), Gaps = 49/501 (9%) Query: 32 GVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWD 91 G + + L + + +S+ P++ + + + E L ++ G + +S+ Sbjct: 2 GSMHSSGKDLNISLPLKTKSIAPYETDVPVKIGAA----ESLFKTNDQGKIEKALVKSYH 57 Query: 92 NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEIL 151 + L+ + K+ +G +TA+ S + S+ + Y+ + G Sbjct: 58 QPNDTTLDIELKDNIKFQNGQKLTAEKVKSSLENSMKKSDLVKYSLPISSITAKG----- 112 Query: 152 EGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNI 211 L + + P L +P AI K Sbjct: 113 ----------------QKLTIKTNSAYPELVSELANPFM------AIYDTDAKSDVNQTP 150 Query: 212 VTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTN 271 V G Y +KD+ + +I L YW K ++ +T V S + D+ Sbjct: 151 VGTGPYQIKDYKQSRKISLSNFKDYW-QGKPKLDHITVTYQEDGNNRVRNLESQKDDLIT 209 Query: 272 NSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNK 331 + +P+ Q ++ +V + T N+ VR AL +DR I + Sbjct: 210 D-VPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNKKMT-KSVREALDHIIDRQGIADH 267 Query: 332 VKAQGNMPA---YGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTIN 388 + PA + PY KLT+ E+AK LLA+ GYT + PL I Sbjct: 268 IYQGYAKPATSPFNDKIPYIKEPKLTKQNI---------EQAKMLLAKDGYTKEHPLKIK 318 Query: 389 LLYNTSDLH-KKLAIAASSLWKK-NIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADY 446 L+ K+A S KK NI +++K V+ + + +L R + G Sbjct: 319 LITYDGRPELSKIAQVLQSDAKKANIEIDIKSVD-DIEGYLKDRSAWDATMYSFGTIPRG 377 Query: 447 NEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIV 506 + F + ++N Y + D ++ + D +R + + +D Sbjct: 378 DTGYFFNQAYKKDGAINKGDYNNSNVDDLINQLNHTVDVKERHNISNDIIKLSSRDVPNS 437 Query: 507 PVYYYVNARLVKPWVGGYTGK 527 + Y V Y Sbjct: 438 YIAYNDQIVAANSKVKNYKVT 458 >4ONY-A nrPDB Length = 595 Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats. Identities = 105/562 (18%), Positives = 198/562 (35%), Gaps = 92/562 (16%) Query: 38 KQTLVRNNGSEVQSLDPHKIEGVPESN--------ISRDLFEGLL--VSDLDGHPAPGVA 87 K +L SL+P ++ + + +++ L+ D +A Sbjct: 44 KGSLTVGVVGTFDSLNPFVLKSMRTTARGLYNDGEFGNMVYQTLMLRSRDEPFTLYSLLA 103 Query: 88 ESWDNKDAKVWT-FHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAG 146 E + W F L AKWSDG PVT D ++++ + PY S + Sbjct: 104 EKVAIDPERKWVEFTLNPKAKWSDGQPVTVDDVLFTYD-ILTEKGRPPYNSRMS------ 156 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEK--FGEK 204 ++ + ++ T +E + +L+ S +PK AI + FG Sbjct: 157 -----------RVAKIEKTGERSVRFTFNEKSDREFPMLIAGSMPVLPKHAINRDTFGNS 205 Query: 205 WTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTV------INQVTYLPIASEVTD 258 +P + +G Y + +RIV +R+P YW ++++ +E + Sbjct: 206 TLEP--PIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNETSL 263 Query: 259 VNRYRSGEIDMTNNSMPIELFQKLK--------KEIPDEVHVDPYLCTYYYEINNQKPPF 310 ++ G +D+ PI ++KL K I D + N ++P F Sbjct: 264 FESFKKGILDIFIEGNPIR-WEKLYDFPAVEQGKVIKDTFEKGTPADMLGFVFNTRRPIF 322 Query: 311 NDVRVRTALKLGMDRDIIVNKVKAQG----------------NMPAYG----YTPPYTDG 350 D RVR AL L D + + + A PA P+ Sbjct: 323 ADRRVRQALGLLFDFEWANSNLFAGQYRRTQSFWEGSQLSSVGRPADARERELLAPFPGA 382 Query: 351 AK-------LTQPEWFGWSQEKRN-EEAKKLLAEAGYTAD---------KPLTINLLYNT 393 + P G ++ ++A LL++AG+ KP ++ + Sbjct: 383 VREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAIDPTAKPFAFEIMTRS 442 Query: 394 SDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDV---ARAGWCADYNEPT 450 D +K+A+A + +G+ V++ + + +D+ A A + NE Sbjct: 443 PD-EEKIALAYQRNLSR-LGIAVEIHTVDDAQYQQRLQTFDYDMILGALASSLSPGNEQW 500 Query: 451 SFLNTMLSN--SSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV 508 + + S N A PA D+++ L + A + ++ L VP+ Sbjct: 501 LRWGSASRDVQGSFNFAGVADPAVDAMIEALLAARNRADFVSAVRALDRVLISGDYYVPL 560 Query: 509 YYYVNARLVKPWVGGYTGKDPL 530 Y+ + + + K PL Sbjct: 561 YHLPYQWVARWDRIEHPQKTPL 582 >4WED-A nrPDB Length = 525 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 107/544 (19%), Positives = 191/544 (35%), Gaps = 58/544 (10%) Query: 3 NITKRSLV--AAGVLAALMAGNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGV 60 ++ +R+ + AAG + MA A TL +LDP + Sbjct: 2 SVKRRTFLQGAAGAIGLAMA----QGALSKIVYAQGAAGTLRVAIAKPAGNLDPQSHYAI 57 Query: 61 PESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDA-KVWTFHLRKDAKWSDGTPVTAQDF 119 I +FE L+ G P +A W +D K LR+ K+ DGT A Sbjct: 58 W--AIQDLMFEPLVKYGKGGQIEPCLATDWKIEDGGKTLHLTLREGVKFQDGTKFDAAAC 115 Query: 120 VYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVP 179 ++ +R GID+ ++ +DD+ + V EPV Sbjct: 116 KWNLER------------------WMGIDQFSWMNCSKHFQSLEVVDDYHITVHFKEPVL 157 Query: 180 YFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNN 239 + L + T P + + + V G + + + V E YW + Sbjct: 158 ALMQELSY--TRPTRFLSPKSVDAD-GKFKEPVGTGPWVQISAD-DTQSVFEHYDGYWGD 213 Query: 240 AKTVINQVTYLPIASEVTDVNRYRSGEIDMTNN----SMPIELFQKLKKEIPDEVHVDPY 295 K ++ I + V R+GEID+ + E ++L+ V VDP Sbjct: 214 -KPTYERLEAKVIPDARSRVAALRAGEIDLVGGFWIAPLTPEEGKQLEAA-GFNVVVDPG 271 Query: 296 LCTYYYEINNQKP-PFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLT 354 T N + P D +VR A+ +G+DR I + PA ++ Sbjct: 272 NVTLVMAFNPDRAEPLKDPQVRKAVSIGIDRAAISKVLYHGYAKPAGNM---FSAALPYA 328 Query: 355 QPEWFGWSQEKRNEEAKKLLAEAGY-------TADKPLTINLLYNTSDL--HKKLAIAAS 405 ++ ++ A LL +AG+ KPLT+ L+ + + + +A Sbjct: 329 GKQFDAPVRDAAA--ASALLEKAGWTGSPIRSKDGKPLTLELVVSPDAVPGSRVIAEVIQ 386 Query: 406 SLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDV-ARAGWCADYNEPTSFLNTMLSNSSMNT 464 S K +G+++ + + + + + +D+ + A Y+ S + LS + Sbjct: 387 SE-MKEVGIDLVIRSVDHASKHTDMLEQKYDLGFFLTYGAPYDPFGSLVALCLSTFKNDV 445 Query: 465 AH--YKSP-AFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWV 521 P D ++ T + + K L + AI P+ Y + V Sbjct: 446 EGKLVTDPVNLDPLINAATAATGDQIEPTI-QKVYDWLRDNDAIAPLVYVPSIWAHSKRV 504 Query: 522 GGYT 525 G+T Sbjct: 505 QGFT 508 >6EQ0-A nrPDB Length = 683 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 109/527 (20%), Positives = 177/527 (33%), Gaps = 86/527 (16%) Query: 72 GLLVSD-LDGHPAPGVAESWD-NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQ-RSVD 128 L D D P P +A+SW+ ++D T HL K AKWSDG A D ++ W+ VD Sbjct: 126 PLFQVDAKDTEPLPNLAKSWEWSEDGHTLTMHLVKGAKWSDGEAFNADDVMFYWEDAVVD 185 Query: 129 PNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVP-YFYKLLVH 187 PN + G A + EG +K IDD+T+E T P + + + Sbjct: 186 PNVSP-------LGGGASPEAFGEG------TTLKKIDDYTVEWTFKAAFPKQYLYTMAY 232 Query: 188 PSTSPVPKAAIEKFGEKWTQPG-------------NIVTNGAYTLKDWVVNERIVLERSP 234 PS P P ++ K+++ N+ GA+ + ++ IVL R+P Sbjct: 233 PSFCPGPSHILKPQHPKYSKNTYNQFKNAFPPEYMNMPVMGAWVPVSYRPDDLIVLRRNP 292 Query: 235 TYW-----NNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKK----E 285 YW +N+V Y DV +G D +N P LK+ Sbjct: 293 YYWKVDEKGQQLPYLNEVHYKLSTWADRDVQAV-AGSGDFSNLEQPENFVASLKRAADPN 351 Query: 286 IPDEVHVDPYLCTYYYEINNQKPPFNDVR--------------VRTALKLGMDRDIIVNK 331 P + P L Y ++N + + R A+ +DR I + Sbjct: 352 APARLAFGPRLIGYNLQMNFSANGWGNPDERGQAIRELNRNEVFRQAVTSALDRKAIGDS 411 Query: 332 VKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTA---------- 381 + P P E AK LA G Sbjct: 412 LVKG---PFTAIYPGGISSGTSFYDRASTVYYPFNLEGAKAALASIGLKDTDGDGFLNFP 468 Query: 382 -----DKPLTINLLYNTSDLH-KKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTF 435 + + I LL N K LA K +G+ V + + + + G F Sbjct: 469 KETLGGRNVEITLLVNNGYATDKSLAEGLVGQMAK-LGLRVVIHSLDSNQRDAAHYGGQF 527 Query: 436 D---VARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFD---------SIMAETLKVT 483 D + + + T L + +S N + D I+ + + Sbjct: 528 DWLVRRNSTELSSVVQNTEQLAPVGPRTSWNHRSPEGKELDLMPFEKEMADIVRKFISSQ 587 Query: 484 DEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPL 530 D A+R L + ++ ++ + + Y A +V P+ Sbjct: 588 DNAERADLMKQYQKVYTQNLYTIGLTEYPGALIVNKRFSNVPQGTPI 634 >2GRV-A nrPDB Length = 621 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 76/463 (16%), Positives = 149/463 (32%), Gaps = 64/463 (13%) Query: 40 TLVRNNGSEVQSLDPHKIEGVP------ESNISRDLFEGLLV-SDLDG---HPAPGVAES 89 ++ S +PH + S + F + + G + ES Sbjct: 49 QIIMAIDSIGPGFNPHLLSDQSPVNAAIASLVLPSSFRPVPDPTSPTGSRWELDTTLLES 108 Query: 90 WD--NKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVD-PNTASPYASYLQYGHIAG 146 + ++ T+ +R +A+W+D P+ A D+ Y W++ V P P Y I G Sbjct: 109 AEVTQENPFTVTYKIRPEAQWTDNAPIAADDYWYLWRQMVSQPGVVDPAG----YDLITG 164 Query: 147 IDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWT 206 + + GK+ + VT S+P P + +L + + K FG Sbjct: 165 VQSVEGGKQAV--------------VTFSQPYPAWRELFNDILPAHIVKDIPGGFGAGLA 210 Query: 207 QPGNIVTNGAYTLKDWVV-NERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSG 265 + VT G + ++ + I+L R+ +W+ + V + + + R+G Sbjct: 211 R-AMPVTGGQFRVETIDPQRDEILLARNDRFWSVP-AKPDLVLFRRGGAPAALADSIRNG 268 Query: 266 EIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDR 325 + + F +L + Q+P D +VR A+ +D Sbjct: 269 DTQVAQVHGGAATFAQLSAIPDVRTARIVTPRVMQLTLRAQQPKLADPQVRKAILGLIDV 328 Query: 326 DIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGY------ 379 D++ + + ++A +LL +AGY Sbjct: 329 DLLASV---GAGDDNTVTLAQAQVRSPSDPGYVPTAPPAMTRDDALELLRDAGYVSEPVP 385 Query: 380 -------------------TADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVK-LV 419 PLTI L ++D ++ +N+G++ L Sbjct: 386 PPDNTADDPPPDNGRERIVKDGVPLTIVLGVASNDPTSVAVANTAADQLRNVGIDASVLA 445 Query: 420 NQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSM 462 + D D A GW + + L + ++ Sbjct: 446 LDPVALYGDALVNNRVD-AVVGWRQAGGDLATVLASRYGCRAL 487 >1NW1-A nrPDB Length = 429 Score = 35.1 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 31/94 (32%), Gaps = 7/94 (7%) Query: 418 LVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMA 477 L++ E+ ++ F W DY+ + N + + Sbjct: 299 LIDFEYASY--NYRAFDFANHFIEWTIDYDIDE---APFYKIQTENFPE-NDQMLEFFLN 352 Query: 478 ETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYY 511 L+ + LY K+E + + VPV ++ Sbjct: 353 -YLREQGNTRENELYKKSEDLVQETLPFVPVSHF 385 >2PMP-A nrPDB Length = 160 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 40/108 (37%), Gaps = 10/108 (9%) Query: 328 IVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADK-PLT 386 +V+ + +P G + P+W G + +EA +L+ EAGY T Sbjct: 47 VVDAILGALGLPDIG------QIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNLDAT 100 Query: 387 INLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGT 434 + L HK S K +G + +VN + KT G Sbjct: 101 LILQRPKISPHK---ETIRSNLSKLLGADPSVVNLKAKTHEKVDSLGE 145 >5JOS-A nrPDB Length = 247 Score = 32.0 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 402 IAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWC--------ADYNEPTSFL 453 I + K++GV V+ V W T + FD+A G AD+++P Sbjct: 50 IDVAKSLAKSLGVKVEFVPTTWPTLMSDLQADKFDIAMGGVTVTPERQKKADFSDPYMTF 109 >1WDT-A nrPDB Length = 665 Score = 31.6 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 49/183 (26%), Gaps = 28/183 (15%) Query: 237 WNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPD-----EVH 291 W K +V + + V + G D E +KL +E P + Sbjct: 363 WQGEKPESEEVPFARLPDPNVPVALHPKGRTDEARLG---EALRKLLEEDPSLKLERQEE 419 Query: 292 VDPYLCTYY--YEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTD 349 L + + K D G++ + V KV P + Sbjct: 420 TGELLLWGHGELHLATAKERLQD--------YGVEVEFSVPKV------PYRETIKKVAE 465 Query: 350 GAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWK 409 G + + G Q + +E G+ I S + + K Sbjct: 466 GQGKYKKQTGGHGQYGDVWLRLEPASEYGFEW----RITGGVIPSKYQEAIEEGIKEAAK 521 Query: 410 KNI 412 K + Sbjct: 522 KGV 524 >1VQZ-A nrPDB Length = 341 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 90 WDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDE 149 WD K F++R+ K++ G V++ Y + +A +++ Sbjct: 248 WDWNYGKSPEFNVRRGIKFTSGKV-----EVFANVTESKIQDIKIYGDFFGIEDVAAVED 302 Query: 150 ILEGKKPITDLGVKAIDDHTLEVT 173 +L G K + +KA+ T+++T Sbjct: 303 VLRGVKYEREDVLKAL--KTIDIT 324 >5TUJ-C nrPDB Length = 235 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 8/58 (13%) Query: 402 IAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWC--------ADYNEPTS 451 I + K +GV V+ V W + G FD+ +G D+++P Sbjct: 39 IDLAKALAKELGVKVEFVPTTWDGIIPALQTGKFDIVMSGMTITPERKKKVDFSDPYM 96 >4EVS-A nrPDB Length = 371 Score = 29.7 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 41/143 (28%), Gaps = 10/143 (6%) Query: 73 LLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTA 132 L + VAE + F R + +P AQ + + V Sbjct: 20 LFGQNFKMGIDAWVAEHGNKVGGHTVEFVYRDEV-----SPNPAQSKALAQELIVKEKVQ 74 Query: 133 SPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSP 192 Y +A + E K P+ L T +T P + +T P Sbjct: 75 YIAGLYFTPNAMAVAPLLQEAKVPMVVLNAA-----TSSITEKSPYIVRTSFTMFQNTVP 129 Query: 193 VPKAAIEKFGEKWTQPGNIVTNG 215 K A +K +K + G Sbjct: 130 AAKVAKQKGAKKVAIAVSDYGPG 152 >3V7C-A nrPDB Length = 329 Score = 29.3 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 20/53 (37%) Query: 217 YTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDM 269 Y + N ++ + + ++ YL + E + +R S +ID Sbjct: 271 YIAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF 323 >4DUR-A nrPDB Length = 791 Score = 28.9 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 19/51 (37%), Gaps = 2/51 (3%) Query: 442 WCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALY 492 W + ++ + N ++ + ++P D + TD +R L Sbjct: 190 WDSQSPHAHGYIPSKFPNKNLKKNYCRNP--DRELRPWCFTTDPNKRWELC 238 >1XTP-A nrPDB Length = 254 Score = 28.6 bits (62), Expect = 7.2, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 26/85 (30%), Gaps = 1/85 (1%) Query: 377 AGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFD 436 AG + LY T+DL + + ++ G+ V T T+D Sbjct: 102 AGIGRITKNLLTKLYATTDLLEPVKHMLEEAKRELAGMPVG-KFILASMETATLPPNTYD 160 Query: 437 VARAGWCADYNEPTSFLNTMLSNSS 461 + W A Y F+ Sbjct: 161 LIVIQWTAIYLTDADFVKFFKHCQQ 185 >4F06-A nrPDB Length = 371 Score = 28.2 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 40/143 (27%), Gaps = 10/143 (6%) Query: 73 LLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTA 132 L + VAE + F R + +P AQ + + V Sbjct: 20 LFGKNYKMGIDAWVAEHGNKVAGHTVEFVYRDEV-----SPNPAQSKALAQELIVKEKVQ 74 Query: 133 SPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSP 192 Y +A + E K P+ + T +T P + +T P Sbjct: 75 YLAGLYFTPNAMAVAPLLQEAKVPMVVMNAA-----TSSITEKSPYIVRTSFTMFQNTVP 129 Query: 193 VPKAAIEKFGEKWTQPGNIVTNG 215 K A +K K + G Sbjct: 130 AAKVAKQKGATKVAIAVSDYGPG 152 >3ZXV-A nrPDB Length = 486 Score = 28.2 bits (61), Expect = 9.6, Method: Composition-based stats. Identities = 23/179 (12%), Positives = 49/179 (27%), Gaps = 26/179 (14%) Query: 55 HKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRK---------- 104 H G F LL + D + ++ ++ K TF + Sbjct: 225 HHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMH 284 Query: 105 --DAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGV 162 + W DG P+ + Y+ S A + G + +L P + Sbjct: 285 CHQSLWKDGAPLMYDETGYA--------GLSDTARHYIGGLLHHAPSLLAFTNPTVNSYK 336 Query: 163 KAIDDHTLEVTL------SEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNG 215 + + + + L +P + + + G + ++ G Sbjct: 337 RLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAG 395 >4B9G-A nrPDB Length = 161 Score = 28.2 bits (61), Expect = 10.0, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 31/88 (35%), Gaps = 3/88 (3%) Query: 410 KNIGVNVKLVNQEWKT-FLDTR--HQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAH 466 + IG V + N + + + G F + G + + + + + + Sbjct: 65 QQIGKLVNVNNPDQNMNYYIRKDSGAGKFMAGQKGSFSVKENTSYTFSAIYTGGEYPNSG 124 Query: 467 YKSPAFDSIMAETLKVTDEAQRTALYTK 494 Y S + + + D QRT + TK Sbjct: 125 YSSGTYAGHLTVSFYSNDNKQRTEIATK 152 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.128 0.326 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,435,420 Number of Sequences: 36641 Number of extensions: 770515 Number of successful extensions: 2318 Number of sequences better than 10.0: 59 Number of HSP's better than 10.0 without gapping: 95 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1830 Number of HSP's gapped (non-prelim): 125 length of query: 543 length of database: 10,336,785 effective HSP length: 102 effective length of query: 441 effective length of database: 6,599,403 effective search space: 2910336723 effective search space used: 2910336723 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 61 (28.2 bits)