BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P23818
(907 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
6QKC-A nrPDB 1852 0.0
4U1Y-A nrPDB 1238 0.0
5IDF-B nrPDB 1228 0.0
5KUF-A nrPDB 645 0.0
5KUH-A nrPDB 312 4e-85
5O9A-A nrPDB 273 2e-73
3FAT-A nrPDB 273 3e-73
3DP4-A nrPDB 270 3e-72
5UOW-A nrPDB 247 2e-65
5FXI-A nrPDB 239 4e-63
5UN1-G nrPDB 222 4e-58
6IRA-D nrPDB 196 5e-50
5UN1-B nrPDB 194 1e-49
5IPR-B nrPDB 184 1e-46
4PE5-B nrPDB 181 1e-45
5UP2-B nrPDB 174 2e-43
1YAE-A nrPDB 171 1e-42
5DT6-A nrPDB 169 5e-42
5L2E-A nrPDB 169 5e-42
5EHM-A nrPDB 162 4e-40
2XXT-A nrPDB 154 2e-37
5IKB-A nrPDB 153 3e-37
4MF3-A nrPDB 153 3e-37
4IGR-A nrPDB 149 7e-36
4WXJ-A nrPDB 102 8e-22
5CC2-A nrPDB 89 9e-18
5I2K-B nrPDB 88 1e-17
3OEK-A nrPDB 85 2e-16
5H8N-A nrPDB 82 8e-16
2RCB-A nrPDB 77 2e-14
2RC9-A nrPDB 75 2e-13
4YKP-A nrPDB 68 2e-11
5TUJ-C nrPDB 56 7e-08
4ZDM-A nrPDB 55 2e-07
4F3P-A nrPDB 52 2e-06
4PSH-A nrPDB 49 1e-05
4ZV2-A nrPDB 47 3e-05
4IO3-A nrPDB 46 6e-05
4F3S-A nrPDB 46 8e-05
3K4U-A nrPDB 45 1e-04
1GGG-A nrPDB 44 3e-04
5JOS-A nrPDB 43 5e-04
4H5F-A nrPDB 42 8e-04
2PYY-A nrPDB 40 0.004
5OTA-A nrPDB 40 0.007
4MS4-A nrPDB 38 0.016
4YMX-A nrPDB 37 0.030
4ZEF-A nrPDB 37 0.031
4I62-A nrPDB 37 0.036
6FXG-A nrPDB 35 0.13
4KPT-A nrPDB 35 0.15
5LOM-A nrPDB 35 0.16
2IEE-A nrPDB 35 0.17
3I6V-A nrPDB 34 0.26
2Q2A-A nrPDB 34 0.34
3EIQ-A nrPDB 33 0.52
4OEN-A nrPDB 33 0.70
3TQL-A nrPDB 33 0.75
5ORE-A nrPDB 32 0.96
2HYI-C nrPDB 32 1.2
5EYF-A nrPDB 32 1.4
5HPQ-A nrPDB 31 2.5
5VXG-A nrPDB 31 2.7
3F41-A nrPDB 30 3.2
6J0J-A nrPDB 30 6.7
6F6P-A nrPDB 29 8.0
5GZU-A nrPDB 29 9.1
>6QKC-A nrPDB
Length = 915
Score = 1852 bits (4796), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 905/915 (98%), Positives = 906/915 (99%), Gaps = 8/915 (0%)
Query: 1 MPYIFAFFCTGFLGAVVGA--------NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 52
MPYIFAFFCTGFLGAVVGA NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP
Sbjct: 1 MPYIFAFFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 60
Query: 53 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112
PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS
Sbjct: 61 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 120
Query: 113 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 172
FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV
Sbjct: 121 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 180
Query: 173 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232
TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN
Sbjct: 181 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 240
Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292
LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSD+RDHTRVDWKRPKYTSAL
Sbjct: 241 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSAL 300
Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352
TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN
Sbjct: 301 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 360
Query: 353 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 412
VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT
Sbjct: 361 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 420
Query: 413 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 472
TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK
Sbjct: 421 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 480
Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532
AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
Query: 533 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 592
DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 600
Query: 593 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652
FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
Query: 653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 712
LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG
Sbjct: 661 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 720
Query: 713 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772
KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV
Sbjct: 721 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 780
Query: 773 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832
LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 840
Query: 833 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIP 892
RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGG GSGENGRVVSQDFPKSMQSIP
Sbjct: 841 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIP 900
Query: 893 CMSHSSGMPLGATGL 907
CMSHSSGMPLGATGL
Sbjct: 901 CMSHSSGMPLGATGL 915
>4U1Y-A nrPDB
Length = 819
Score = 1238 bits (3204), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 589/830 (70%), Positives = 703/830 (84%), Gaps = 16/830 (1%)
Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQIDIVNISDSFEMTYRFCSQFSKG 81
N+IQIGGLFP QE++AFR + Q T +L P ID + +++SF +T FCSQFS+G
Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRG 60
Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYK 141
VYAIFGFY++++VN +TSFCG LHV FITPSFP D ++ FV+Q+RP+L+ AL+S+I++Y+
Sbjct: 61 VYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQ 120
Query: 142 WQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT----EEGYRMLFQDLEKKKE 197
W F Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+ +E YR LFQDLE KKE
Sbjct: 121 WDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKE 180
Query: 198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257
R V++DCE +++N I+ Q++ + K+ GYHYI+ANLGF D DL K + GA V+GFQ+V+
Sbjct: 181 RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVD 240
Query: 258 YTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRR 317
Y D++ ++ +++W T + +++ KYTSALTYD V+VM EAF++LR+QRI+ISRR
Sbjct: 241 YDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRR 300
Query: 318 GNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIR 377
GNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F++ G+R NYT++++E+K +G R
Sbjct: 301 GNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPR 360
Query: 378 KIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEG 437
KIGYW+E DK V T+ D S ++ +T +VTTILE PYVM+KKN EGN+RYEG
Sbjct: 361 KIGYWSEVDKMVVTLTE----DDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEG 416
Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITL 497
YCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WNGMVGELVYG+AD+A+APLTITL
Sbjct: 417 YCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITL 476
Query: 498 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 557
VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSVVLFLV
Sbjct: 477 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLV 536
Query: 558 SRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGG 617
SRFSPYEWH+EEFE+G + T NEFGIFNS WF+L F QQG DISPRSLS RIV G
Sbjct: 537 SRFSPYEWHTEEFEDGEEST-----NEFGIFNSFWFALKLFFQQGADISPRSLSARIVAG 591
Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSK 677
VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTL++GSTKEFFRRSK
Sbjct: 592 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK 651
Query: 678 IAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 737
IAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV
Sbjct: 652 IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 711
Query: 738 GGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDK 797
GGNLDSKGYGIATPKGS+L PVNLAVLKLSEQGVLDKLK+KWWYDKGECG+KDSGSK+K
Sbjct: 712 GGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEK 771
Query: 798 TSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847
TSALSLSNVAGVFYIL+GGLGLAMLVALIEF YKSR+E+KRMKG L+P+
Sbjct: 772 TSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMKG--LVPR 819
>5IDF-B nrPDB
Length = 874
Score = 1228 bits (3176), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 591/830 (71%), Positives = 692/830 (83%), Gaps = 11/830 (1%)
Query: 21 FPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEPP-KLLPQIDIVNISDSFEMTYR 73
FPN I IGGLF QEH+AFRFA+ TE P L +D ++ S+SF +T
Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69
Query: 74 FCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEAL 133
FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D QFV+Q+RP L+ A+
Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129
Query: 134 ISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE-EGYRMLFQDL 192
+S++ +YKW+ FVY+YD +RG SVLQ +++ A + NWQVTA ++ + + +R + +++
Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189
Query: 193 EKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTG 252
++++E+ ++DCE ER+N IL Q+V L K+ GYHY+LANLGF DI L + GAN+TG
Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249
Query: 253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRI 312
FQ+VN + + + +Q+W D + KYTSALT+D + V+AEAF+ LRRQR+
Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309
Query: 313 DISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK 372
D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+ GRRTNYT+ V EMK
Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369
Query: 373 HDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGN 432
G RK GYWNE ++FVP +D Q D+SS +NRT +VTTILE PYVM KKN Q EGN
Sbjct: 370 VSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 428
Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492
+RYEGYCV+LA EIAKHVG Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAP
Sbjct: 429 ERYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 488
Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552
LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV
Sbjct: 489 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 548
Query: 553 VLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSL 610
VLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIFNSLWFSLGAFMQQGCDISPRSL
Sbjct: 549 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 608
Query: 611 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTK 670
SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL++GSTK
Sbjct: 609 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 668
Query: 671 EFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK 730
EFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+LLESTMNEYIEQRK
Sbjct: 669 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 728
Query: 731 PCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
PCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAVLKLSEQG+LDKLK+KWWYDKGECG+K
Sbjct: 729 PCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 788
Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
DSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ESKRMK
Sbjct: 789 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 838
>5KUF-A nrPDB
Length = 877
Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 352/848 (41%), Positives = 516/848 (60%), Gaps = 54/848 (6%)
Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74
++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + +
Sbjct: 5 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 64
Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128
C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 65 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 124
Query: 129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188
L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + L
Sbjct: 125 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 183
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
+++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG
Sbjct: 184 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 243
Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304
N+TGF+++N +T + I+++W + + D +AL YD V V++ A
Sbjct: 244 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 303
Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363
Q + + ++ C N PW G +++ +EGLTG + FN+ G RT+
Sbjct: 304 QQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 355
Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416
+ L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE
Sbjct: 356 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 409
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG
Sbjct: 410 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNG 469
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
MV EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+
Sbjct: 470 MVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLS 529
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLG 596
+IWM ++ AY+GVSVVLF+++RFSPYEW++ + + N F + NS WF +G
Sbjct: 530 PDIWMYVLLAYLGVSVVLFVIARFSPYEWYN---PHPCNPDSDVVENNFTLLNSFWFGVG 586
Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
A MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQ
Sbjct: 587 ALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQ 646
Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716
T+I YG +E GST FF++SKI+ ++KMW +M S SV V+++EEG+ RV S YA
Sbjct: 647 TKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYAL 704
Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L +
Sbjct: 705 LMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMM 763
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
K KWW G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ +
Sbjct: 764 KEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA 819
Query: 837 KRMK-GFC 843
+ K FC
Sbjct: 820 QLEKRSFC 827
>5KUH-A nrPDB
Length = 757
Score = 312 bits (800), Expect = 4e-85, Method: Compositional matrix adjust.
Identities = 203/595 (34%), Positives = 314/595 (52%), Gaps = 57/595 (9%)
Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74
++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + +
Sbjct: 5 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 64
Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128
C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 65 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 124
Query: 129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188
L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + L
Sbjct: 125 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 183
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
+++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG
Sbjct: 184 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 243
Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304
N+TGF+++N +T + I+++W + + D +AL YD V V++ A
Sbjct: 244 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 303
Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363
Q + + ++ C N PW G +++ +EGLTG + FN+ G RT+
Sbjct: 304 QQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 355
Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416
+ L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE
Sbjct: 356 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 409
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG
Sbjct: 410 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNG 469
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQKSKPGVFSFLDP 534
MV EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K P S D
Sbjct: 470 MVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSA-------DD 522
Query: 535 LAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTTSDQSNEFGI 587
LA + + G ++ F S+ S Y+ W F R Q+ +S+E GI
Sbjct: 523 LAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMW---AFMSSRRQSVLVKSSEEGI 574
Score = 179 bits (453), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 92/203 (45%), Positives = 135/203 (66%), Gaps = 8/203 (3%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PI+SA+DLAKQT+I YG +E GST FF++SKI+ ++KMW +M S SV V+++E
Sbjct: 512 RKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSE 571
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RV S YA L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R +
Sbjct: 572 EGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 628
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAM 821
+A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL L++
Sbjct: 629 IAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSV 684
Query: 822 LVALIEFCYKSRSESK-RMKGFC 843
VA+ EF YKS+ ++ + FC
Sbjct: 685 FVAVGEFLYKSKKNAQLEKRSFC 707
>5O9A-A nrPDB
Length = 264
Score = 273 bits (699), Expect = 2e-73, Method: Compositional matrix adjust.
Identities = 130/145 (89%), Positives = 140/145 (96%)
Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704
+PIESAEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+
Sbjct: 119 TPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 178
Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764
RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+L VNLAV
Sbjct: 179 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAV 238
Query: 765 LKLSEQGVLDKLKSKWWYDKGECGS 789
LKLSEQG+LDKLK+KWWYDKGECGS
Sbjct: 239 LKLSEQGLLDKLKNKWWYDKGECGS 263
Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 92/115 (80%), Positives = 102/115 (88%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
N+T +VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYG
Sbjct: 3 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYG 62
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
ARD DTK WNGMVGELVYG+AD+A+APLTIT VREEVIDFSKPFMSLGISIMIKK
Sbjct: 63 ARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKK 117
>3FAT-A nrPDB
Length = 260
Score = 273 bits (697), Expect = 3e-73, Method: Compositional matrix adjust.
Identities = 128/144 (88%), Positives = 139/144 (96%)
Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704
+PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+
Sbjct: 117 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 176
Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764
RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+LR PVNLAV
Sbjct: 177 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAV 236
Query: 765 LKLSEQGVLDKLKSKWWYDKGECG 788
LKLSE GVLDKLK+KWWYDKGECG
Sbjct: 237 LKLSEAGVLDKLKNKWWYDKGECG 260
Score = 197 bits (500), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 90/114 (78%), Positives = 102/114 (89%)
Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
RT +VTTI+E PYVM KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGA
Sbjct: 2 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 61
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
RD DTK WNGMVGELVYG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 62 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 115
>3DP4-A nrPDB
Length = 278
Score = 270 bits (689), Expect = 3e-72, Method: Compositional matrix adjust.
Identities = 126/144 (87%), Positives = 139/144 (96%)
Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704
+PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+
Sbjct: 135 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 194
Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764
RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAV
Sbjct: 195 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAV 254
Query: 765 LKLSEQGVLDKLKSKWWYDKGECG 788
LKLSEQG+LDKLK+KWWYDKGECG
Sbjct: 255 LKLSEQGILDKLKNKWWYDKGECG 278
Score = 207 bits (526), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 100/133 (75%), Positives = 108/133 (81%)
Query: 388 FVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIA 447
VP + D+S NRT +VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIA
Sbjct: 1 LVPRGSAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIA 60
Query: 448 KHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSK 507
KHV Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSK
Sbjct: 61 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 120
Query: 508 PFMSLGISIMIKK 520
PFMSLGISIMIKK
Sbjct: 121 PFMSLGISIMIKK 133
>5UOW-A nrPDB
Length = 814
Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 220/879 (25%), Positives = 398/879 (45%), Gaps = 135/879 (15%)
Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 77
P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C
Sbjct: 2 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 59
Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125
S VYAI + + LT S+ + V +T + + F+ +
Sbjct: 60 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 119
Query: 126 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 183
P +AL+ ++ + W + I D Q+ L+T E+ + + + + E
Sbjct: 120 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 177
Query: 184 GYRMLFQDLEKKKE---RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 240
G + L L + KE R++++ + A+ L+ G GY +++ G +I
Sbjct: 178 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 234
Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVM 300
+ + + + G QL+N K SA D V V+
Sbjct: 235 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 266
Query: 301 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 358
A+A L ++I RG C+ N + W G +R L ++ +G+TG ++FNE
Sbjct: 267 AQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNED 321
Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 411
G R ++ +++ + ++G ++ D K + P + G S + + +
Sbjct: 322 GDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 378
Query: 412 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 442
TI ++P+V ++ + + Y G+CV+L
Sbjct: 379 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDL 438
Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLV 498
++A+ + ++Y + +V+DGK+G ++ + AWNGM+GEL+ G+AD+ VAPLTI
Sbjct: 439 LIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNE 498
Query: 499 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 558
R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+
Sbjct: 499 RAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 557
Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIV 615
RFSP+ GR + S + E + +++WFS + G + +PRS S RI+
Sbjct: 558 RFSPF---------GRFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARIL 608
Query: 616 GGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEF 672
G VW F +II++SYTANLAAFL + R I D + + Y T++ S +
Sbjct: 609 GMVWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIY 668
Query: 673 FRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPC 732
FRR M+ +M+ + E + VR +K +A++ +S + E+ E + C
Sbjct: 669 FRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQDC 720
Query: 733 DTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDS 792
D + G G+GI K S + V+L +LK E G +++L K W EC S+ +
Sbjct: 721 DLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRSN 779
Query: 793 GSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYK 831
+ L+ N+AGVFY++ GG+ + + IE YK
Sbjct: 780 AP----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814
>5FXI-A nrPDB
Length = 846
Score = 239 bits (610), Expect = 4e-63, Method: Compositional matrix adjust.
Identities = 184/697 (26%), Positives = 329/697 (47%), Gaps = 108/697 (15%)
Query: 188 LFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESG 247
L + + + R++++ + + L+ G GY +++ G +I N + +
Sbjct: 206 LLMEARELEARVIILSASEDDAATVYRAAAMLDMTGSGYVWLV---GEREISGNALRYAP 262
Query: 248 ANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL 307
+ G QL+N K SA D V V+A+A L
Sbjct: 263 DGIIGLQLIN----------------------------GKNESAHISDAVGVVAQAVHEL 294
Query: 308 -RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEKGRRTNYT 365
++ I RG C+ N + W G +R L ++ +G+TG V+FNE G R
Sbjct: 295 LEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQ 349
Query: 366 LHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIVTTILEDP 418
++ +++ + ++G +N D K + P + G S + + + TI ++P
Sbjct: 350 YSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLK---IVTIHQEP 406
Query: 419 YVMLKKNA-------------------------NQFEGNDRYE------GYCVELAAEIA 447
+V +K + G+ R+ G+C++L ++A
Sbjct: 407 FVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLA 466
Query: 448 KHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVI 503
+ + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI R + I
Sbjct: 467 RTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYI 526
Query: 504 DFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPY 563
+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ RFSP
Sbjct: 527 EFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSP- 584
Query: 564 EWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGGVWWFF 622
F + + S+ ++ + +++WFS G + G + +PRS S RI+G VW F
Sbjct: 585 ------FGRFKVNSQSESTDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGF 638
Query: 623 TLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIA 679
+II++SYTANLAAFL ++R I D + + Y T++ S +FRR
Sbjct: 639 AMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--V 696
Query: 680 VFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG 739
M+ +M+ + E + VR +K +A++ +S + E+ E + CD + G
Sbjct: 697 ELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGE 750
Query: 740 NLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTS 799
G+GI K S + V+L++LK E G ++ L K W EC S+ + +
Sbjct: 751 LFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDL-DKTWVRYQECDSRSNAP----A 805
Query: 800 ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
L+ N+AGVF ++ GG+ + + IE YK ++
Sbjct: 806 TLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDA 842
>5UN1-G nrPDB
Length = 451
Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 139/419 (33%), Positives = 231/419 (55%), Gaps = 37/419 (8%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAP 492
G+CV+L ++A+ + ++Y + +V+DGK+G ++ + AWNGM+GEL+ G+AD+ VAP
Sbjct: 62 GFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAP 121
Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552
LTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V
Sbjct: 122 LTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 180
Query: 553 VLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLS 611
+L+L+ RFSP+ GR + + + +++WFS + G + +PRS S
Sbjct: 181 MLYLLDRFSPF---------GRFE------DALTLSSAMWFSWRVLLNSGLGEGAPRSFS 225
Query: 612 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGS 668
RI+G VW F +II++SYTANLAAFL + R I D + + Y T++ S
Sbjct: 226 ARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSS 285
Query: 669 TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQ 728
+FRR M+ +M+ + E + VR +K +A++ +S + E+ E
Sbjct: 286 VDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EA 337
Query: 729 RKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
+ CD + G G+GI K S + V+L +LK E G +++L K W EC
Sbjct: 338 SQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECD 396
Query: 789 SKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847
S+ + + L+ N+AGVF ++ GG+ + + IE YKSR+E+KRMKG ++ Q
Sbjct: 397 SRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLFQ 451
>6IRA-D nrPDB
Length = 853
Score = 196 bits (497), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 193/774 (24%), Positives = 344/774 (44%), Gaps = 106/774 (13%)
Query: 114 PVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN---W 170
P T QF ++ + ++ I+ Y W F + G + T + + W
Sbjct: 140 PTSTFFQFGASIQQQ-ATVMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGW 198
Query: 171 QVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYIL 230
+ V L T+ E + Q L+K ++++ C + IL + L G + +I+
Sbjct: 199 DMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIV 257
Query: 231 ANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKY 288
+L G ++ +F +G V+Y D W S
Sbjct: 258 PSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------------- 287
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISR-RGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
A DG+ ++ A S+ + I + + + P VP + + V ++
Sbjct: 288 LEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHT---LHPFMVNVTWD 344
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAAT--DAQAGGDNSSV 404
G ++ F E+G + + L VI + D K+G W + A ++ D
Sbjct: 345 G--KDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPD 402
Query: 405 QNRTYIVTTILEDPYVML---------------------KKNANQFEGNDRYE---GYCV 440
N IVT + E P+V++ K N + EG + + G+C+
Sbjct: 403 DNHLSIVT-LEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCI 461
Query: 441 ELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVRE 500
++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI R
Sbjct: 462 DILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTINEERS 519
Query: 501 EVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVS 558
EV+DFS PF+ GIS+M+ + + P +FL+P + +W M V I ++ +F+
Sbjct: 520 EVVDFSVPFVETGISVMVSRSNGTVSPS--AFLEPFSASVWVMMFVMLLIVSAIAVFVFE 577
Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGG 617
FSP ++ +G+ + F I ++W G + +P+ + +I+
Sbjct: 578 YFSPVG-YNRNLAKGK----APHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVS 632
Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAY------GTLEAGSTKE 671
VW FF +I ++SYTANLAAF+ R V + D Q Y GT+ GST+
Sbjct: 633 VWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTER 692
Query: 672 FFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-K 730
R + + YM + E+ ++ ++ K A++ ++ + Y R +
Sbjct: 693 NIRNN--------YPYMHQYMTKFNQKGVEDALVSLKTGKLD-AFIYDAAVLNYKAGRDE 743
Query: 731 PCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
C + +G + GYGIA KGS + ++LA+L+ G +++L++ W G C
Sbjct: 744 GCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGIC- 800
Query: 789 SKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE-FCYKSRSESKRMKG 841
+ ++ +S L + N+AGVFY+L + L+++ + E YKSR+E+KRMKG
Sbjct: 801 -HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMKG 853
>5UN1-B nrPDB
Length = 448
Score = 194 bits (493), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 130/425 (30%), Positives = 226/425 (53%), Gaps = 45/425 (10%)
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
+G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA +AV LTI
Sbjct: 56 KGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTI 113
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVV 553
R EV+DFS PF+ GIS+M+ + + P +FL+P + ++W M V I +V
Sbjct: 114 NEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLLIVSAVA 171
Query: 554 LFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 612
+F+ FSP ++ F G+ ++W G + +P+ +
Sbjct: 172 VFVFEYFSPVGYNGPSFTIGK---------------AIWLLWGLVFNNSLPVQNPKGTTS 216
Query: 613 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEA 666
+I+ VW FF +I ++SYTANLAAF+ R V + D Q +GT+
Sbjct: 217 KIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPN 276
Query: 667 GSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYI 726
GST+ R + + +M +YM R+ ++ ++ ++ K A++ ++ + Y+
Sbjct: 277 GSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDAAVLNYM 327
Query: 727 EQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783
R + C + +G + GYGIA K S + V+LA+L+L G +++L++ W
Sbjct: 328 AGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL-- 385
Query: 784 KGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE-FCYKSRSESKRMKGF 842
G C + ++ +S L + N+AGVFY+L + L+++ ++E YKSR+E+KRMKG
Sbjct: 386 TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGL 443
Query: 843 CLIPQ 847
++ Q
Sbjct: 444 EVLFQ 448
>5IPR-B nrPDB
Length = 825
Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 187/833 (22%), Positives = 366/833 (43%), Gaps = 127/833 (15%)
Query: 57 PQIDIVNI--SDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP 114
P++++V + SD + R C S F + + + V +TP
Sbjct: 61 PRVELVTMQESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILG 120
Query: 115 VDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRV 161
+ + ++ Q P +++ +++I++ Y W F + G +
Sbjct: 121 IHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENK 180
Query: 162 LDTAAEKN---WQVTAVNILTTTEEGYRMLFQD-LEKKKERLVVVDCESERLNAILGQIV 217
+ + E + W++ V L + + Q+ L+K + ++++ C E I
Sbjct: 181 VRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAH 240
Query: 218 KLEKNGIGYHYILANLGFMDIDL--NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDA 275
+ G G+ +I+ +L D D ++F TG V+Y +W
Sbjct: 241 SVGLTGYGFTWIVPSLVAGDTDTVPDEFP------TGLISVSY---------DEW----- 280
Query: 276 RDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGI 335
D+ P A DG+ ++ A ++ + I + ++ + + V +
Sbjct: 281 ------DYDLP----ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YEAH 328
Query: 336 DIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAATD 394
++R L V FEG ++ F+E G + + L +I + + ++G + + + D
Sbjct: 329 MLKRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPVFD 386
Query: 395 AQAGGDNSSVQNRTYIVTTILEDPYVMLK--------------------KNANQFEGNDR 434
+ ++ + + T+ E P+V+++ + N+ E
Sbjct: 387 LYPNSEEHKDEHLS--IVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGN 444
Query: 435 Y-----EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
Y +G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA +A
Sbjct: 445 YIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMA 502
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAY 547
V LTI R EV+DFS PF+ GIS+M+ + + P +FL+P + ++W M V
Sbjct: 503 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLL 560
Query: 548 IGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-S 606
I +V +F+ FSP ++ F G+ ++W G + +
Sbjct: 561 IVSAVAVFVFEYFSPVGYNGPSFTIGK---------------AIWLLWGLVFNNSLPVQN 605
Query: 607 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIA 660
P+ + +I+ VW FF +I ++SYTANLAAF+ R V + D Q
Sbjct: 606 PKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFR 665
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
+GT+ GST+ R + + +M +YM R+ ++ ++ ++ K A++ ++
Sbjct: 666 FGTVPNGSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDA 716
Query: 721 TMNEYIEQRKP-CDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777
+ Y+ R C + +G + GYGIA K S + V+LA+L+L G +++L+
Sbjct: 717 AVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELE 776
Query: 778 SKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
+ W G C + ++ +S L + N+AGVFY+L + L+++ ++E +
Sbjct: 777 ALWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825
>4PE5-B nrPDB
Length = 820
Score = 181 bits (459), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 191/771 (24%), Positives = 341/771 (44%), Gaps = 136/771 (17%)
Query: 116 DTSNQFVLQLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN--- 169
D S+ F Q P +++ +++I++ Y W F + G + + E +
Sbjct: 112 DESSMF-FQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVG 170
Query: 170 WQVTAVNILTTT-EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHY 228
W++ V +L + ++G + L+K + ++++ C E I + G GY +
Sbjct: 171 WELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTW 230
Query: 229 ILANLGFMDIDL--NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRP 286
I+ +L D D ++F TG V+Y +W D+ P
Sbjct: 231 IVPSLVAGDTDTVPSEFP------TGLISVSY---------DEW-----------DYGLP 264
Query: 287 KYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF 346
A DG+ ++ A + + I ++ C Q + R L V F
Sbjct: 265 ----ARVRDGIAIITTAASDMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTF 318
Query: 347 EGLTGNVQFNEKGRRTNYTLHVIEM-KHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQ 405
EG ++ F+E G + + L +I + K ++G W + S+Q
Sbjct: 319 EG--RDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKD-----------------KSLQ 359
Query: 406 NRTYI-----------VTTILEDPYVMLKK--------------------NANQFEGNDR 434
+ Y+ + T+ E P+V+++ + N+ +
Sbjct: 360 MKYYVWPRMTQDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPG 419
Query: 435 Y-----EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
Y +G+C+++ +I+K V ++Y L +V++GK+G + T WNGM+GE+V RA +A
Sbjct: 420 YIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGT--WNGMIGEVVMKRAYMA 477
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAY 547
V LTI R EV+DFS PF+ GIS+M+ + + P +FL+P + +W M V
Sbjct: 478 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSACVWVMMFVMLL 535
Query: 548 IGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-S 606
I +V +F+ FSP ++ +GR+ F I ++W G + +
Sbjct: 536 IVSAVAVFVFEYFSPVGYN-RSLADGREPG----GPSFTIGKAIWLLWGLVFNNSVPVQN 590
Query: 607 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIA 660
P+ + +I+ VW FF +I ++SYTANLAAF+ E V + D Q
Sbjct: 591 PKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFR 650
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
+GT+ GST+ R + + +M YM R ++ ++ ++ K A++ ++
Sbjct: 651 FGTVPNGSTERNIRNN----YAEMHAYMGKFNQ----RGVDDALLSLKTGKLD-AFIYDA 701
Query: 721 TMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777
+ Y+ R + C + +G S GYGIA K S + V+LA+L+L G +++L+
Sbjct: 702 AVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELE 761
Query: 778 SKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF 828
+ W G C + ++ +S L N+AGVFY+ LG AM ++LI F
Sbjct: 762 ALWL--TGIC--HNEKNEVMSSQLDCDNMAGVFYM----LGAAMALSLITF 804
>5UP2-B nrPDB
Length = 831
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 174/738 (23%), Positives = 321/738 (43%), Gaps = 96/738 (13%)
Query: 132 ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN---WQVTAVNILTTTEEGYRML 188
+++I++ Y W F I G + T + + W+V L T+ + L
Sbjct: 149 VMLNIMEEYDWHVFSVITSNFPGYRDFISFIKTTVDNSFVGWEVQNYITLDTSYTDAQTL 208
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
Q L+K ++++ C + I + L G G+ +I+ +L
Sbjct: 209 TQ-LKKIHSSVILLYCSKDEATYIFEEARSLGLMGYGFVWIVPSL--------------- 252
Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLR 308
VTG TD IP S + DW A DG+ ++ A ++
Sbjct: 253 -VTG-----NTDIIPYEF-----PSGLVSVSYDDWDYG--IEARVRDGLGIITTAASAML 299
Query: 309 RQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHV 368
+ I + C + + V ++G ++ F E G + N L V
Sbjct: 300 EKHSVIPEAKTS--CYGQNERNDPPLHTLHNFMINVTWDG--KDLSFTEDGYQANPKLVV 355
Query: 369 IEMKHD-GIRKIGYW-----------------NEDDKFVPAATDAQAGGDNSSVQNRTYI 410
+ + + K+G W + DD + T +A V+N Y+
Sbjct: 356 LLLNMEREWEKVGKWEAKSLNMKYPVWPRIDSDHDDNHLSIVTLEEA--PFVIVENIDYL 413
Query: 411 VTTILEDP-----YVMLKKNANQFEGNDRY-EGYCVELAAEIAKHVGYSYRLEIVSDGKY 464
T + + Y L + + + +G+C+++ +++K V ++Y L +V++GK+
Sbjct: 414 TGTCVRNTVPCRKYFRLANSTTEGTSVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKH 473
Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524
G + + WNGM+GE+VY RA +AV LTI R +DFS PF+ GIS+M+ + +
Sbjct: 474 GKKIKN--VWNGMIGEVVYKRAVMAVGSLTINEERSVAVDFSVPFVETGISVMVSRSAGT 531
Query: 525 -KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQS 582
P +FL+P + +W M V + ++ +F+ FSP ++ +G+D
Sbjct: 532 VSPS--AFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFSPVG-YNRNLAQGKDP----HG 584
Query: 583 NEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVE 641
F I ++W G + +P+ + +I+ +W FF +I ++SYTANLAAF+
Sbjct: 585 PSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWAFFAVIFLASYTANLAAFMIQR 644
Query: 642 RMVSPIESAEDLAKQTEIAY------GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695
R V + D Q Y GT+ GST+ R + + M YM
Sbjct: 645 RFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIRNN----YPDMHQYMVKFHQ-- 698
Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPK 752
+ ++ ++ ++ K A++ ++ + Y+ R + C + +G + GYGIA K
Sbjct: 699 --KGVQDALVSLKTGKLD-AFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQK 755
Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYI 812
GS + P++LA+L+ G +++L+ W G C ++ ++ +S L + N+AGVFY+
Sbjct: 756 GSRWKRPIDLALLQFVGDGEMEELEKLWL--TGICHTEK--NEVMSSQLDIDNMAGVFYM 811
Query: 813 LIGGLGLAMLVALIEFCY 830
L + L+++ + E +
Sbjct: 812 LAAAMALSLITFVWEHLF 829
>1YAE-A nrPDB
Length = 312
Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 94/207 (45%), Positives = 126/207 (60%), Gaps = 25/207 (12%)
Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462
S+ NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DG
Sbjct: 9 SLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDG 68
Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 522
KYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +KP
Sbjct: 69 KYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPN 128
Query: 523 KSKPGVFSFL--------------------DPLAYEIWMCIVFAYIGVSVVLFLVSRFSP 562
+ PGVFSFL D LA + + G ++ F S+ S
Sbjct: 129 GTNPGVFSFLNGGSLVPRGSERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKIST 188
Query: 563 YE--WHSEEFEEGRDQTTSDQSNEFGI 587
Y+ W F R Q+ +SNE GI
Sbjct: 189 YDKMWA---FMSSRRQSVLVKSNEEGI 212
Score = 154 bits (389), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 79/165 (47%), Positives = 112/165 (67%), Gaps = 7/165 (4%)
Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT 700
ERM SPI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++
Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208
Query: 701 EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPV 760
EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R +
Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265
Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSN 805
+A+L+L E+G L +K KWW G C ++S + SAL + N
Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQN 306
>5DT6-A nrPDB
Length = 267
Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 82/143 (57%), Positives = 105/143 (73%), Gaps = 1/143 (0%)
Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704
+PI++ EDL QT++ YGTL GST EFFRRS+I + KMW YM +A V T +EG+
Sbjct: 125 TPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSVHTYDEGI 183
Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764
RVR+SKGKYA L+ES NEY+ R PCDTMKVG N+D+KG+G+ATP GS LR +N AV
Sbjct: 184 RRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAV 243
Query: 765 LKLSEQGVLDKLKSKWWYDKGEC 787
L L E G L ++++KWW+DK EC
Sbjct: 244 LTLKENGELLRIRNKWWFDKTEC 266
Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 63/119 (52%), Positives = 84/119 (70%), Gaps = 3/119 (2%)
Query: 405 QNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462
+N TYIV+++LE+PY+ LK+ GNDR+EGYC +LA +A +G Y + +V DG
Sbjct: 5 RNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDG 64
Query: 463 KYGARDPDTKA-WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
YGA + W+GMVGEL+ AD+A++ +TIT RE VIDFSKPFM+LGISIMIKK
Sbjct: 65 NYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKK 123
>5L2E-A nrPDB
Length = 688
Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 123/538 (22%), Positives = 245/538 (45%), Gaps = 55/538 (10%)
Query: 25 IQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCSQF 78
I IG +F ++ FR A+ L + ++L + V+ ++ F+ C
Sbjct: 6 IHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELM 65
Query: 79 SKGVYAIFGFYERRTVNMLTSFCGALHV----------------CFITPSFPVDTSNQFV 122
++G+ A+ + L S A+H+ C +T S + ++ +
Sbjct: 66 NQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRS---NRNDDYT 122
Query: 123 LQLRPE--LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTT 180
L +RP L E ++ ++ Y WQ F+ YD++ + +Q LD +++ V +
Sbjct: 123 LSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 182
Query: 181 TEEGYRMLF-----QDLEKKKE--RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANL 233
+ LF ++L + ++ R ++ + + ++V+ H+I+ N
Sbjct: 183 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINE 242
Query: 234 GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQ-WRTSDARDHTRVDWKRP-----K 287
D+D+ + ++ ++ T +P I Q+ +R + T D K P +
Sbjct: 243 EINDVDVQELVRR--SIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNME 300
Query: 288 YTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
++ YD V ++A AF + R S + C+ + PW G + +++
Sbjct: 301 ISNLYIYDTVLLLANAFHKKLQDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGVN 358
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHD-----GIRKIGYWNEDDKFVPAATDAQAGGDNS 402
GLTG+++F E G N ++ + G+RK+G WN + TD + +
Sbjct: 359 GLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMR 418
Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462
V R V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D
Sbjct: 419 GVVLR---VVTVLEEPFVMVSENV--LGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDH 473
Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
KYG+ D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++
Sbjct: 474 KYGSPQED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 530
Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 10/154 (6%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAEPSV 695
R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + S
Sbjct: 529 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSE 588
Query: 696 F-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753
V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA G
Sbjct: 589 NNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 646
Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787
S R + +L+L + G +D LK KWW G+C
Sbjct: 647 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 680
>5EHM-A nrPDB
Length = 268
Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/149 (54%), Positives = 105/149 (70%), Gaps = 4/149 (2%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PIESAEDLAKQT I YG L+ GST FFR SKI+ +++MW++M+SA PSVF +
Sbjct: 120 RKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNG 179
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RV K KG YA+L+EST EY+ +R C+ +VGG LD+K YGIATP S R +N
Sbjct: 180 EGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAIN 238
Query: 762 LAVLKLSEQGVLDKLKSKWWYDK---GEC 787
+LKL E+G L LK+KWW +K G+C
Sbjct: 239 SVILKLQEEGKLHILKTKWWKEKRGGGKC 267
Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 58/120 (48%), Positives = 92/120 (76%)
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460
+++++N+T +VTTIL +PY M K++A GND++EGY V+L EI+K +G++Y++++V
Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61
Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K
Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121
>2XXT-A nrPDB
Length = 261
Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 87/186 (46%), Positives = 117/186 (62%), Gaps = 14/186 (7%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYG
Sbjct: 3 NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYG 62
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQK 523
A+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K P
Sbjct: 63 AQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGTPID 122
Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTTSDQ 581
S D LA + + G ++ F S+ S Y+ W F R Q+ +
Sbjct: 123 SA-------DDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWA---FMSSRRQSVLVK 172
Query: 582 SNEFGI 587
SNE GI
Sbjct: 173 SNEEGI 178
Score = 145 bits (367), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 70/144 (48%), Positives = 100/144 (69%), Gaps = 3/144 (2%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ E
Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNE 175
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R +
Sbjct: 176 EGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 232
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785
+A+L+L E+G L +K KWW G
Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256
>5IKB-A nrPDB
Length = 257
Score = 153 bits (387), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 76/146 (52%), Positives = 100/146 (68%), Gaps = 4/146 (2%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PIES +DLA QT I YGT+ GS+ FF+ S+ +++MW YM S +PSVFV++TE
Sbjct: 115 RKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTE 174
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RV S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R +
Sbjct: 175 EGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFD 231
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGEC 787
LA+L+L E L+ LK KWW + G+C
Sbjct: 232 LAILQLQENNRLEILKRKWW-EGGKC 256
Score = 140 bits (352), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 76/161 (47%), Positives = 107/161 (66%), Gaps = 10/161 (6%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
N T +VTTILE+PY+MLK N EGNDRYEG+CV++ E+A+ + ++Y++ +V DG YG
Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQK 523
+ + W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K P +
Sbjct: 63 VPEAN-GTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTPIE 121
Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564
S +D LA + + + G S+ F SR+ Y+
Sbjct: 122 S-------VDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQ 155
>4MF3-A nrPDB
Length = 261
Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 92/202 (45%), Positives = 124/202 (61%), Gaps = 15/202 (7%)
Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462
S+ NRT IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y +++V DG
Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60
Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK-- 520
KYGA++ D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K
Sbjct: 61 KYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGT 119
Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTT 578
P S D LA + + G ++ F S+ S YE W F R QT
Sbjct: 120 PIDSA-------DDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMW---AFMSSRQQTA 169
Query: 579 SDQSNEFGIFNSLWFSLGAFMQ 600
++++ GI L M+
Sbjct: 170 LVRNSDEGIQRVLTTDYALLME 191
Score = 142 bits (358), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 69/144 (47%), Positives = 98/144 (68%), Gaps = 3/144 (2%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PI+SA+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + + VR ++
Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSD 175
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R +
Sbjct: 176 EGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKIT 232
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785
+A+L+L E+G L +K KWW G
Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256
>4IGR-A nrPDB
Length = 258
Score = 149 bits (375), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 68/115 (59%), Positives = 91/115 (79%), Gaps = 1/115 (0%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
NR+ IVTT+LE+P+VM +K+ GNDR+EGYC++L E+A +G+SY + +V DGKYG
Sbjct: 5 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYG 64
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
A+D D WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K
Sbjct: 65 AQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRK 118
Score = 140 bits (354), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 71/144 (49%), Positives = 98/144 (68%), Gaps = 4/144 (2%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ FEKMW +M S++PS V+ E
Sbjct: 117 RKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVKNNE 175
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ R + YA L+EST EYI QR C+ ++GG +DSKGYGI TP GS R +
Sbjct: 176 EGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRDKIT 232
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785
+A+L+L E+ L +K KWW G
Sbjct: 233 IAILQLQEEDKLHIMKEKWWRGSG 256
>4WXJ-A nrPDB
Length = 269
Score = 102 bits (254), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 1/137 (0%)
Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704
+ I S DL Q ++ +GT+ G+T +F S W M S +P F + EEG+
Sbjct: 126 TDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGV 185
Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764
RV+ SKG YA+L+E+T +Y QR C+ ++G + K YGIA P + R +++ +
Sbjct: 186 DRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRSNLSVGI 244
Query: 765 LKLSEQGVLDKLKSKWW 781
L+LSE+G L KL++KW+
Sbjct: 245 LRLSERGELFKLRNKWF 261
Score = 93.6 bits (231), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 44/114 (38%), Positives = 67/114 (58%), Gaps = 2/114 (1%)
Query: 409 YIVTTILEDPYVMLKKNAN--QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
Y V T + PY ++ +EGN+R+EGY V+L +A+ + + E V D KYG+
Sbjct: 11 YTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGS 70
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
D +T W+G++ +L+ A + + LTIT R V+DF+ PFM LGISI+ K
Sbjct: 71 YDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYK 124
>5CC2-A nrPDB
Length = 265
Score = 89.0 bits (219), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 38/110 (34%), Positives = 72/110 (65%), Gaps = 3/110 (2%)
Query: 411 VTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPD 470
V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D KYG+ D
Sbjct: 7 VVTVLEEPFVMVSENV--LGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQED 64
Query: 471 TKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++
Sbjct: 65 -GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 113
Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 10/154 (6%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAEPSV 695
R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + S
Sbjct: 112 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSE 171
Query: 696 F-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753
V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA G
Sbjct: 172 NNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 229
Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787
S R + +L+L + G +D LK KWW G+C
Sbjct: 230 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 263
>5I2K-B nrPDB
Length = 293
Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 38/88 (43%), Positives = 64/88 (72%), Gaps = 4/88 (4%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAP 492
G+C++L ++A+ + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAP
Sbjct: 66 GFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 125
Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKK 520
LTI R + I+FSKPF G++I++KK
Sbjct: 126 LTINNERAQYIEFSKPFKYQGLTILVKK 153
Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
Y T++ S +FRR M+ +M+ + E + VR +K +A++ +S
Sbjct: 174 YATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDS 226
Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
+ E+ E + CD + G G+GI K S + V+L++LK E G ++ L K
Sbjct: 227 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DKT 284
Query: 781 WYDKGECGS 789
W EC S
Sbjct: 285 WVRYQECDS 293
>3OEK-A nrPDB
Length = 286
Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 36/85 (42%), Positives = 59/85 (69%), Gaps = 2/85 (2%)
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
+G+C+++ +A +G+SY L +V++GK+G + WNGM+GE+ Y RAD+A+ LTI
Sbjct: 60 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKI--DGVWNGMIGEVFYQRADMAIGSLTI 117
Query: 496 TLVREEVIDFSKPFMSLGISIMIKK 520
R E++DFS PF+ GIS+M+ +
Sbjct: 118 NEERSEIVDFSVPFVETGISVMVAR 142
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/126 (25%), Positives = 66/126 (52%), Gaps = 14/126 (11%)
Query: 659 IAYGTLEAGSTKEFFRRSKIAVFEKMWTYM-KSAEPSVFVRTTEEGMIRVRKSKGKYAYL 717
+ +GT+ GST++ R + + M +YM + +P V EE + +++ K A++
Sbjct: 164 LKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGKLD-AFI 213
Query: 718 LESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLD 774
++ + Y+ ++ + C + +G + GYGIA KGS + P++LA+L+ ++
Sbjct: 214 YDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIE 273
Query: 775 KLKSKW 780
L+ W
Sbjct: 274 MLERLW 279
>5H8N-A nrPDB
Length = 285
Score = 82.4 bits (202), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 36/85 (42%), Positives = 60/85 (70%), Gaps = 2/85 (2%)
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
+G+C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI
Sbjct: 59 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 116
Query: 496 TLVREEVIDFSKPFMSLGISIMIKK 520
R EV+DFS PF+ GIS+M+ +
Sbjct: 117 NEERSEVVDFSVPFVETGISVMVSR 141
Score = 38.5 bits (88), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
+GT+ GST+ R + + YM + E+ ++ ++ K A++ ++
Sbjct: 165 FGTVPNGSTERNIRNN--------YPYMHQYMTKFNQKGVEDALVSLKTGKLD-AFIYDA 215
Query: 721 TMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777
+ Y R + C + +G + GYGIA KGS + ++LA+L+ G +++L+
Sbjct: 216 AVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELE 275
Query: 778 SKW 780
+ W
Sbjct: 276 TLW 278
>2RCB-A nrPDB
Length = 292
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 36/84 (42%), Positives = 54/84 (64%), Gaps = 4/84 (4%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGA-RDPDTKAWNGMVGELVYGRADVAVAPLTI 495
GYC++L +A+ + + + L IV DGKYGA RD W G+VG+L+ GRA +AV +I
Sbjct: 68 GYCIDLLERLAEDLAFDFELYIVGDGKYGALRD---GRWTGLVGDLLAGRAHMAVTSFSI 124
Query: 496 TLVREEVIDFSKPFMSLGISIMIK 519
R +V+DF+ PF S + IM++
Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVR 148
Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 11/130 (8%)
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY-AYLLE 719
+GT+ S + + + A F +M +M+ TT G+ + K A++++
Sbjct: 171 FGTVWESSAEAYIK----ASFPEMHAHMRRHS----APTTPHGVAMLTSDPPKLNAFIMD 222
Query: 720 STMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778
++ +Y + C + VG +GYGI P+ S L ++ + + G +D L
Sbjct: 223 KSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHD 282
Query: 779 KWWYDKGECG 788
K WY CG
Sbjct: 283 K-WYKMVPCG 291
>2RC9-A nrPDB
Length = 294
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 33/83 (39%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496
GYC++L ++A+ + + + L IV DGKYGA W G+VG+L+ G A++AV +I
Sbjct: 70 GYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NGHWTGLVGDLLSGTANMAVTSFSIN 127
Query: 497 LVREEVIDFSKPFMSLGISIMIK 519
R +VIDF+ PF S + I+++
Sbjct: 128 TARSQVIDFTSPFFSTSLGILVR 150
Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 10/123 (8%)
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY-AYLLE 719
+GT+ S +++ R+S F +M YM+ V T +G+ ++ K A++++
Sbjct: 173 FGTVRESSAEDYVRQS----FPEMHEYMRRYN----VPATPDGVQYLKNDPEKLDAFIMD 224
Query: 720 STMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778
+ +Y + C + VG +GYGI P S L ++ + + G +D L
Sbjct: 225 KALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHD 284
Query: 779 KWW 781
KW+
Sbjct: 285 KWY 287
>4YKP-A nrPDB
Length = 256
Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 3/137 (2%)
Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
R + ++ E P++ EGND + G ++ ++++ +G++Y D K+GA
Sbjct: 8 RHLRLGSVEEQPFMFFATEG--CEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGA 65
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526
+ T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K +
Sbjct: 66 LNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLN 125
Query: 527 GVFSFLDPLAYEIWMCI 543
V LD Y+ W I
Sbjct: 126 QVLELLDQDKYK-WGVI 141
Score = 36.2 bits (82), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 23/49 (46%)
Query: 732 CDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
CD VG S Y PK S + ++ +LK E+G +D L KW
Sbjct: 200 CDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKW 248
>5TUJ-C nrPDB
Length = 235
Score = 56.2 bits (134), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 13/102 (12%)
Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491
N +Y G+ ++LA +AK +G ++E V P T W+G++ L G+ D+ ++
Sbjct: 31 NGQYTGFDIDLAKALAKELGV--KVEFV---------PTT--WDGIIPALQTGKFDIVMS 77
Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 533
+TIT R++ +DFS P+M+ G +I++KK K F L+
Sbjct: 78 GMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLN 119
Score = 29.3 bits (64), Expect = 9.0, Method: Composition-based stats.
Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 22/140 (15%)
Query: 647 IESAEDLAK---QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEG 703
I+S EDL K + + GT + KEF ++KI FE E
Sbjct: 112 IKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE----------------NNAEA 155
Query: 704 MIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKGSA-LRGPVN 761
V + A + +S + Y ++ P + V + G A KG L VN
Sbjct: 156 FQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKGDPELLNWVN 214
Query: 762 LAVLKLSEQGVLDKLKSKWW 781
+ ++ + G DKL KW+
Sbjct: 215 NWLKQMKKDGTYDKLYEKWF 234
>4ZDM-A nrPDB
Length = 261
Score = 55.1 bits (131), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 47/85 (55%)
Query: 435 YEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLT 494
Y G VE+ + +++ + ++Y D K+G ++ T WNG++ +L+ + D+ V L+
Sbjct: 37 YTGVNVEIVSMMSQDLNFTYNFITPEDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALS 96
Query: 495 ITLVREEVIDFSKPFMSLGISIMIK 519
VR+ IDFS M G+ ++K
Sbjct: 97 NNAVRKADIDFSLSMMDGGLGALVK 121
Score = 33.5 bits (75), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 687 YMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGY 746
Y + AE +V V + EG+ R+R G + ++ E Y + CD +++G
Sbjct: 161 YNRIAEDAVKVGSYGEGLERMRA--GGFVFIDEIPGINY-ATKGECDIVQIGETFQPFEL 217
Query: 747 GIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784
K S + V+ +L + EQGV+ +L +K+ K
Sbjct: 218 AFGLRKNSPFKNLVDTFMLGIREQGVISELYAKYENQK 255
>4F3P-A nrPDB
Length = 249
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 13/92 (14%)
Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487
+F+ D+Y G+ ++L AEIAK G++Y+++ + + G++ L D
Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
VA++ +TI R + IDFS P+ G++ M++
Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQ 116
Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 21/45 (46%)
Query: 737 VGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781
G + YGI PKGS L VN + ++ G K+ KW+
Sbjct: 197 AGAPVSGDKYGIGFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241
>4PSH-A nrPDB
Length = 227
Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 34/131 (25%), Positives = 66/131 (50%), Gaps = 22/131 (16%)
Query: 404 VQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461
+++R Y++ + D P+ + +N N G+ V+LA EIA+ +G L+IV
Sbjct: 5 IKSRGYLLVGLSADFPPFEFVDENGNIV-------GFDVDLAKEIARRLGV--ELKIVD- 54
Query: 462 GKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 521
++G++ L+ + DV ++ +TIT R++V+ FS P+ G I+++K
Sbjct: 55 ----------MTFDGLIPSLLTKKIDVIISGMTITEERKKVVAFSDPYFDAGQVIVVRKD 104
Query: 522 QKSKPGVFSFL 532
+P + L
Sbjct: 105 SDFRPKTYEDL 115
>4ZV2-A nrPDB
Length = 233
Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%)
Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491
N + G+ ++LA IAK +G + + ++G++ L G+ DV +A
Sbjct: 29 NGKLVGFDIDLAKAIAKKLGVKVEFKPMD-------------FDGIIPALQSGKIDVVIA 75
Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524
+TIT R++ +DFS P+ G +I++KK S
Sbjct: 76 GMTITEERKKQVDFSDPYFEAGQAIVVKKGNDS 108
Score = 32.3 bits (72), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 725 YIEQRKPCDTMKVGGNLDSKGYGIATPKG-SALRGPVNLAVLKLSEQGVLDKLKSKWW 781
Y++Q VG + YGIA KG S L +N A+ ++ + G DK+ KW+
Sbjct: 174 YVKQNPNAGVKIVGETFSGEPYGIAVRKGNSELLEKINKALEEMKKDGTYDKIYEKWF 231
>4IO3-A nrPDB
Length = 248
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 32/61 (52%)
Query: 724 EYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783
EY+ C+ VG + D +GI TPK +++ +L L E G+LD LK KW+
Sbjct: 185 EYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQT 244
Query: 784 K 784
K
Sbjct: 245 K 245
Score = 36.6 bits (83), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
Query: 434 RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPL 493
+ GY ++L + +G+ +++ P ++ G+V L G D+A+ +
Sbjct: 36 KLTGYVLDLIEYLRDKMGFVADVQLA---------PPNTSYTGLVLALANGDYDIAIGDI 86
Query: 494 TITLVREEVIDFSKPFMSLGISIMIKK 520
T+T R E++ FS + I+++K
Sbjct: 87 TVTSARREIVAFSNSISDNSMRILMRK 113
>4F3S-A nrPDB
Length = 255
Score = 45.8 bits (107), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 19/37 (51%), Positives = 30/37 (81%)
Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPF 509
AW+GM+G + G+ADVA + ++IT R++VIDFS+P+
Sbjct: 56 AWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPY 92
>3K4U-A nrPDB
Length = 245
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 30/160 (18%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
P+ M K N G+ V+LA E+AK +G +L S W+G+
Sbjct: 17 PFEMKDKKGNVI-------GFDVDLAREMAKAMGVKLKLVPTS-------------WDGL 56
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537
+ LV + D+ ++ +TI+ R ++F +P++ +G S+++KK + GV S+ D
Sbjct: 57 IPGLVTEKFDIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEK--GVKSYKDLDKP 114
Query: 538 EIWMCIVFAYIGVSVV-----LFLVSRFSPYEWHSEEFEE 572
E+ + F GVS LF ++ Y+ +E +E
Sbjct: 115 ELTLVTKF---GVSAEYAAKRLFKNAKLKTYDTEAEAVQE 151
>1GGG-A nrPDB
Length = 226
Score = 44.3 bits (103), Expect = 3e-04, Method: Composition-based stats.
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 13/92 (14%)
Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487
+F+ D Y G+ V+L A IAK + Y L+ + ++G++ L D
Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
+A+A +TIT R++ IDFS + G+ +M+K
Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVK 95
Score = 40.4 bits (93), Expect = 0.004, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Query: 737 VGGNLDSKGYGIATPKGS-ALRGPVNLAVLKLSEQGVLDKLKSKWW 781
VG +L+++ YGIA PKGS LR VN A+ L E G +++ KW+
Sbjct: 176 VGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWF 221
>5JOS-A nrPDB
Length = 247
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 13/92 (14%)
Query: 434 RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPL 493
+Y G+ +++A +AK +G ++E V P T W ++ +L + D+A+ +
Sbjct: 44 QYTGFDIDVAKSLAKSLGV--KVEFV---------PTT--WPTLMSDLQADKFDIAMGGV 90
Query: 494 TITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525
T+T R++ DFS P+M+ G + +++K K
Sbjct: 91 TVTPERQKKADFSDPYMTFGKTPLVRKEDADK 122
>4H5F-A nrPDB
Length = 243
Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats.
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 13/96 (13%)
Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
+G ++ G +++A IA +G +LEI+S +++ ++ L G+AD+A
Sbjct: 32 DGKNQVVGADIDMAQAIADELGV--KLEILS-----------MSFDNVLTSLQTGKADLA 78
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525
VA ++ T R+EV DFS P+ IS ++ K K
Sbjct: 79 VAGISATDERKEVFDFSIPYYENKISFLVHKADVEK 114
>2PYY-A nrPDB
Length = 228
Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 20/49 (40%), Positives = 24/49 (48%)
Query: 737 VGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKG 785
VG L + YGI P S R P+N A+L L E G L KW+ K
Sbjct: 177 VGSILREESYGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWFDPKN 225
Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 20/110 (18%)
Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
+V T + P+V+ K G+ ++L IA +G +L
Sbjct: 6 LVATRVIPPFVLSNKG--------ELSGFSIDLWRSIATQIGIESKLI------------ 45
Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
+ + ++ + + ++ +A ++IT RE+ DFS P + G+ IM++
Sbjct: 46 EYSSVPELISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95
>5OTA-A nrPDB
Length = 265
Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 26/39 (66%)
Query: 472 KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510
+AW+G++ L GR D +A + I RE+VI FS+P++
Sbjct: 51 QAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYL 89
>4MS4-A nrPDB
Length = 420
Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 337 IQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE-DDKFVPAATDA 395
I RA+ FEG++G+V F+ G R +TL + +++ +KIGY++ D + TD
Sbjct: 345 IYRAMNSSSFEGVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYDSTKDDLSWSKTDK 403
Query: 396 QAGG 399
GG
Sbjct: 404 WIGG 407
>4YMX-A nrPDB
Length = 260
Score = 37.4 bits (85), Expect = 0.030, Method: Composition-based stats.
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 13/76 (17%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G D G+ +++A IAK +G +LEI +D D K G++ L GR D+ +
Sbjct: 58 GKDEIVGFDIDIANAIAKKLGV--KLEI--------KDMDFK---GLIPALQAGRVDMVI 104
Query: 491 APLTITLVREEVIDFS 506
A +T T R++ +DFS
Sbjct: 105 AGMTPTAERKKSVDFS 120
>4ZEF-A nrPDB
Length = 251
Score = 37.4 bits (85), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 18/37 (48%), Positives = 24/37 (64%)
Query: 484 GRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
G+AD VA +TIT R++ DFS P+ GI I +KK
Sbjct: 86 GQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKK 122
>4I62-A nrPDB
Length = 269
Score = 37.0 bits (84), Expect = 0.036, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 13/91 (14%)
Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
+G ++ G +ELA IA +G L +S ++ ++ + G+AD+A
Sbjct: 59 DGKNQIVGSDIELAKAIATELGVELELSPMS-------------FDNVLASVQSGKADLA 105
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
++ ++ T R +V DFS P+ + +++KK
Sbjct: 106 ISGVSKTDERSKVFDFSTPYYTAKNKLIVKK 136
>6FXG-A nrPDB
Length = 227
Score = 35.4 bits (80), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 13/93 (13%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G ++ G V++ E+AK ++LE+ G ++ + L G+ D +
Sbjct: 22 GQKKWVGIDVDIMQEVAKI--NDWKLEMSYPG-----------FDAALQNLKAGQVDGII 68
Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523
A +TIT R+E DFS P+ + ++I K K
Sbjct: 69 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 101
>4KPT-A nrPDB
Length = 251
Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 13/93 (13%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G ++ G V++ E+AK ++LE+ G ++ + L G+ D +
Sbjct: 46 GQKKWVGIDVDIMQEVAKI--NDWKLEMSYPG-----------FDAALQNLKAGQVDGII 92
Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523
A +TIT R+E DFS P+ + ++I K K
Sbjct: 93 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 125
>5LOM-A nrPDB
Length = 269
Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 17/100 (17%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
PY + N + G+ +EL +A +G+ + + ++ A P
Sbjct: 43 PYAFTTADGN-------FTGFDIELFLNVAGRLGFKKEQVVFTGQEFSALMP-------- 87
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIM 517
+ GR DVA A + T R+E +DFS +++ +S++
Sbjct: 88 --SVANGRFDVAAAAIGTTAKRKETVDFSDGYLAGFLSVL 125
>2IEE-A nrPDB
Length = 271
Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats.
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 14/90 (15%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G+D+ GY VE+ E AK +G + +GM+ + G+ D A
Sbjct: 42 GSDKLTGYEVEVVREAAKRLGLKVEFK-------------EMGIDGMLTAVNSGQVDAAA 88
Query: 491 APLTITLVREEVIDFSKPF-MSLGISIMIK 519
+ +T REE FS P+ S G +I+ K
Sbjct: 89 NDIDVTKDREEKFAFSTPYKYSYGTAIVRK 118
>3I6V-A nrPDB
Length = 232
Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 14/37 (37%), Positives = 25/37 (67%)
Query: 474 WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510
W+ ++ LV G D +A ++IT R+EVIDF++ ++
Sbjct: 53 WDSIIPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89
>2Q2A-A nrPDB
Length = 272
Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496
G+ V+L + K G Y L+ + W+ + L D+ ++ +TIT
Sbjct: 65 GFDVDLLDAVMKAAGLDYELKNI-------------GWDPLFASLQSKEVDMGISGITIT 111
Query: 497 LVREEVIDFSKPFMSLGISIMIKK 520
R++ DFS P+ I++K+
Sbjct: 112 DERKQSYDFSDPYFEATQVILVKQ 135
>3EIQ-A nrPDB
Length = 414
Score = 33.1 bits (74), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 501 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 556
+V++ +K FM I I++KK + + G+ F + E W +C ++ + ++ +
Sbjct: 227 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 286
Query: 557 VSRFSPYEWHSEEFEEGRDQTTS 579
++ +W +E+ RD T S
Sbjct: 287 INTRRKVDWLTEKM-HARDFTVS 308
>4OEN-A nrPDB
Length = 223
Score = 32.7 bits (73), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 22/142 (15%)
Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491
+++Y G +EL IAK G+ +EI + G ++ + + G+AD +A
Sbjct: 22 SNQYTGIDMELIKAIAKDQGF--EIEITNPG-----------FDAAISAVQAGQADGIIA 68
Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551
+++T R+ DFS+ + + + +K+ + S+ D + V G +
Sbjct: 69 GMSVTDARKATFDFSESYYTANTILGVKESSN----IASYED-----LKGKTVGVKNGTA 119
Query: 552 VVLFLVSRFSPYEWHSEEFEEG 573
FL S Y + + F +G
Sbjct: 120 SQTFLTENQSKYGYKIKTFADG 141
>3TQL-A nrPDB
Length = 227
Score = 32.7 bits (73), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 12/49 (24%), Positives = 26/49 (53%)
Query: 472 KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
+ W+ ++ L G+ D + IT R++ +DF+ P+ + +S + K
Sbjct: 48 QPWDSLIPSLKLGKFDALFGGMNITTARQKEVDFTDPYYTNSVSFIADK 96
>5ORE-A nrPDB
Length = 263
Score = 32.3 bits (72), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 474 WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMS--LGISIMIKKPQKSKPGV 528
W+G++ L + D +A +++T R+EVI FS P+ + G ++M PG+
Sbjct: 52 WDGIMPSLTGKKYDAIMAAMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGL 108
>2HYI-C nrPDB
Length = 413
Score = 32.0 bits (71), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 14/77 (18%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 501 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 556
E+++ + FM+ I I++K+ + + G+ F + E W +C ++ + ++ +
Sbjct: 224 EILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIF 283
Query: 557 VSRFSPYEWHSEEFEEG 573
+ +W +E+ E
Sbjct: 284 CNTKRKVDWLTEKMREA 300
>5EYF-A nrPDB
Length = 245
Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525
L G D +A +TIT R++ +DFS + G ++++KK + K
Sbjct: 74 LKNGNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIK 118
Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 737 VGGNLDSKGYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGE 786
VGG ++ YGIA KG VN A+ ++ G DK+ KW+ ++ E
Sbjct: 191 VGGTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETE 241
>5HPQ-A nrPDB
Length = 255
Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 22/109 (20%)
Query: 435 YEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLT 494
Y G+ V++A +A+ +G +L +V +W ++ + R D+A++ ++
Sbjct: 45 YAGFDVDMAQRLAESLGA--KLVVVP-----------TSWPNLMRDFADDRFDIAMSGIS 91
Query: 495 ITLVREEVIDFSKPFMSLG---ISIMIKKP------QKSKPGVFSFLDP 534
I L R+ FS P++ G I++ ++ Q +PGV + ++P
Sbjct: 92 INLERQRQAYFSIPYLRDGKTPITLCSEEARFQTLEQIDQPGVTAIVNP 140
>5VXG-A nrPDB
Length = 358
Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 15/101 (14%)
Query: 579 SDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLS-GRIVGGVWWFFTLIIISSYTANLAAF 637
SD F + N+ AF+ G DI+ R L G I +++ TANL
Sbjct: 131 SDHCMTFDVANACL----AFIN-GMDIAARMLERGEI-------DYALVVDGETANLVYE 178
Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKI 678
T+ERM SP + E+ + E+A TL G+ RS++
Sbjct: 179 KTLERMTSPDVTEEEF--RNELAALTLGCGAAAMVMARSEL 217
>3F41-A nrPDB
Length = 629
Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 13/81 (16%)
Query: 184 GYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKF 243
G ++ +L+K K + +D + ++ +++ + +EKNG+ Y+ I A +
Sbjct: 462 GKSLIVAELDKDK---MPIDPKPVKIESVMTEQQLVEKNGLHYYRIAAT--------DHI 510
Query: 244 KESGANVTGFQLVNYTDTIPA 264
S AN+ F +N+T T+PA
Sbjct: 511 WPSAANIDEF--INFTRTMPA 529
>6J0J-A nrPDB
Length = 302
Score = 29.6 bits (65), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 38/165 (23%), Positives = 68/165 (41%), Gaps = 31/165 (18%)
Query: 357 EKGRRTNYTLHVIEMKHD--GIRKIGYWN----EDDKFVPAATDAQAGGDNSSVQNRTYI 410
EK R+ Y L ++E++ + GI ++ Y + +F D Q GD ++
Sbjct: 117 EKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIA----- 171
Query: 411 VTTILEDPYVMLKKNANQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
+ K +F + D +GY AA ++ S + E+ ++ K ARD
Sbjct: 172 -----------ISKEGVKFSSSGDVGQGYTFLQAAGVSDR---STKSEVKAEVKAEARDD 217
Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514
D + + YG+AD + + + + EE I S +GI
Sbjct: 218 DEEPLSRK-----YGKADSSANAIGVEVTMEEPITLSFALRFMGI 257
>6F6P-A nrPDB
Length = 106
Score = 29.3 bits (64), Expect = 8.0, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 24/41 (58%)
Query: 176 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQI 216
++L E+GY L ++L K + L + D E ERL+ + Q+
Sbjct: 10 SVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQL 50
>5GZU-A nrPDB
Length = 885
Score = 29.3 bits (64), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 19/113 (16%)
Query: 718 LESTMNEYIEQRKPCDTMKVGG--------NLDSKGYGIATPKGSALRGPVNLAVLKLSE 769
++ST+ Y+ P + + VGG N+++KG G++ GS P + +L
Sbjct: 259 VDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGLSEKAGSQAGSPGTIVYSELVN 318
Query: 770 QGVLDKLKSKWWYDKGEC-----GSKDSGSKDKTSA------LSLSNVAGVFY 811
+ +++W D + GS +D SA + +N+AG Y
Sbjct: 319 NYINKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGFMY 371
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
6QKC-A nrPDB 1344 0.0
5IDF-B nrPDB 1098 0.0
4U1Y-A nrPDB 1085 0.0
5KUF-A nrPDB 983 0.0
5IPR-B nrPDB 744 0.0
5UOW-A nrPDB 742 0.0
6IRA-D nrPDB 740 0.0
4PE5-B nrPDB 730 0.0
5FXI-A nrPDB 727 0.0
5UP2-B nrPDB 725 0.0
5KUH-A nrPDB 612 e-175
5L2E-A nrPDB 494 e-140
5UN1-G nrPDB 487 e-138
5UN1-B nrPDB 485 e-137
1YAE-A nrPDB 244 2e-64
2XXT-A nrPDB 228 8e-60
3FAT-A nrPDB 228 9e-60
5O9A-A nrPDB 228 1e-59
3DP4-A nrPDB 227 2e-59
4MF3-A nrPDB 225 6e-59
4IGR-A nrPDB 216 3e-56
5IKB-A nrPDB 205 6e-53
5EHM-A nrPDB 205 1e-52
5DT6-A nrPDB 197 2e-50
5CC2-A nrPDB 175 6e-44
4WXJ-A nrPDB 173 4e-43
5I2K-B nrPDB 164 1e-40
5H8N-A nrPDB 157 2e-38
4YKP-A nrPDB 154 2e-37
3OEK-A nrPDB 144 2e-34
2RC9-A nrPDB 143 3e-34
5TUJ-C nrPDB 131 2e-30
4ZDM-A nrPDB 120 3e-27
3K4U-A nrPDB 120 3e-27
2RCB-A nrPDB 120 4e-27
4PSH-A nrPDB 113 4e-25
4ZV2-A nrPDB 104 1e-22
5JOS-A nrPDB 104 2e-22
4F3P-A nrPDB 101 2e-21
1GGG-A nrPDB 98 2e-20
4IO3-A nrPDB 96 8e-20
4H5F-A nrPDB 91 2e-18
4F3S-A nrPDB 64 2e-10
Sequences not found previously or not previously below threshold:
4YMX-A nrPDB 85 1e-16
4G4P-A nrPDB 84 3e-16
4I62-A nrPDB 81 3e-15
2Q2A-A nrPDB 79 9e-15
4ZEF-A nrPDB 74 3e-13
2PYY-A nrPDB 70 5e-12
5HPQ-A nrPDB 69 9e-12
5X2N-B nrPDB 68 2e-11
4OEN-A nrPDB 68 2e-11
4KPT-A nrPDB 66 7e-11
6FXG-A nrPDB 66 8e-11
5EYF-A nrPDB 65 1e-10
4MS4-A nrPDB 62 9e-10
5X2M-A nrPDB 62 1e-09
4F11-A nrPDB 62 1e-09
4KQP-A nrPDB 61 2e-09
3TQL-A nrPDB 61 3e-09
2IEE-A nrPDB 60 5e-09
5OTA-A nrPDB 60 5e-09
2Y7I-A nrPDB 60 6e-09
3VV5-A nrPDB 59 9e-09
5K5S-A nrPDB 58 2e-08
5FBH-B nrPDB 58 2e-08
5LOM-A nrPDB 58 2e-08
5ORE-A nrPDB 57 3e-08
1HSL-A nrPDB 55 1e-07
3I6V-A nrPDB 54 3e-07
1IIT-A nrPDB 54 3e-07
1ISS-A nrPDB 54 3e-07
3DEL-B nrPDB 54 4e-07
5OWF-A nrPDB 52 8e-07
1YK0-A nrPDB 52 1e-06
3A3K-A nrPDB 46 6e-05
4Q0C-A nrPDB 42 0.001
2Q88-A nrPDB 41 0.003
4PX2-A nrPDB 33 0.46
4DX0-A nrPDB 33 0.72
4V8M-A5 nrPDB 32 1.2
5XXU-I nrPDB 32 1.7
5OPT-Z nrPDB 31 2.1
3AXY-C nrPDB 31 2.6
3IP9-A nrPDB 31 2.9
4V6W-AI nrPDB 30 4.9
2F6U-A nrPDB 30 5.5
5A5X-A nrPDB 29 8.6
>6QKC-A nrPDB
Length = 915
Score = 1344 bits (3478), Expect = 0.0, Method: Composition-based stats.
Identities = 905/915 (98%), Positives = 906/915 (99%), Gaps = 8/915 (0%)
Query: 1 MPYIFAFFCTGFLGAVVGA--------NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 52
MPYIFAFFCTGFLGAVVGA NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP
Sbjct: 1 MPYIFAFFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 60
Query: 53 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112
PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS
Sbjct: 61 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 120
Query: 113 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 172
FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV
Sbjct: 121 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 180
Query: 173 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232
TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN
Sbjct: 181 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 240
Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292
LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSD+RDHTRVDWKRPKYTSAL
Sbjct: 241 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSAL 300
Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352
TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN
Sbjct: 301 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 360
Query: 353 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 412
VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT
Sbjct: 361 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 420
Query: 413 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 472
TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK
Sbjct: 421 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 480
Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532
AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
Query: 533 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 592
DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 600
Query: 593 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652
FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
Query: 653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 712
LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG
Sbjct: 661 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 720
Query: 713 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772
KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV
Sbjct: 721 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 780
Query: 773 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832
LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 840
Query: 833 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIP 892
RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGG GSGENGRVVSQDFPKSMQSIP
Sbjct: 841 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIP 900
Query: 893 CMSHSSGMPLGATGL 907
CMSHSSGMPLGATGL
Sbjct: 901 CMSHSSGMPLGATGL 915
>5IDF-B nrPDB
Length = 874
Score = 1098 bits (2840), Expect = 0.0, Method: Composition-based stats.
Identities = 589/830 (70%), Positives = 691/830 (83%), Gaps = 11/830 (1%)
Query: 21 FPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIVNISDSFEMTYR 73
FPN I IGGLF QEH+AFRFA+ + +P L +D ++ S+SF +T
Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69
Query: 74 FCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEAL 133
FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D QFV+Q+RP L+ A+
Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129
Query: 134 ISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE-EGYRMLFQDL 192
+S++ +YKW+ FVY+YD +RG SVLQ +++ A + NWQVTA ++ + + +R + +++
Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189
Query: 193 EKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTG 252
++++E+ ++DCE ER+N IL Q+V L K+ GYHY+LANLGF DI L + GAN+TG
Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249
Query: 253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRI 312
FQ+VN + + + +Q+W D + KYTSALT+D + V+AEAF+ LRRQR+
Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309
Query: 313 DISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK 372
D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+ GRRTNYT+ V EMK
Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369
Query: 373 HDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGN 432
G RK GYWNE ++FVP +D Q D+SS +NRT +VTTILE PYVM KKN Q EGN
Sbjct: 370 VSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 428
Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492
+RYEGYCV+LA EIAKHVG Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAP
Sbjct: 429 ERYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 488
Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552
LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV
Sbjct: 489 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 548
Query: 553 VLFLVSRFSPYEWHSE-EFEEGRD-QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSL 610
VLFLVSRFSPYEWH E EE RD Q+ D NEFGIFNSLWFSLGAFMQQGCDISPRSL
Sbjct: 549 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 608
Query: 611 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTK 670
SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL++GSTK
Sbjct: 609 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 668
Query: 671 EFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK 730
EFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+LLESTMNEYIEQRK
Sbjct: 669 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 728
Query: 731 PCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
PCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAVLKLSEQG+LDKLK+KWWYDKGECG+K
Sbjct: 729 PCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 788
Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
DSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ESKRMK
Sbjct: 789 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 838
>4U1Y-A nrPDB
Length = 819
Score = 1085 bits (2805), Expect = 0.0, Method: Composition-based stats.
Identities = 587/825 (71%), Positives = 699/825 (84%), Gaps = 14/825 (1%)
Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQIDIVNISDSFEMTYRFCSQFSKG 81
N+IQIGGLFP QE++AFR + Q T +L P ID + +++SF +T FCSQFS+G
Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRG 60
Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYK 141
VYAIFGFY++++VN +TSFCG LHV FITPSFP D ++ FV+Q+RP+L+ AL+S+I++Y+
Sbjct: 61 VYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQ 120
Query: 142 WQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT----EEGYRMLFQDLEKKKE 197
W F Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+ +E YR LFQDLE KKE
Sbjct: 121 WDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKE 180
Query: 198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257
R V++DCE +++N I+ Q++ + K+ GYHYI+ANLGF D DL K + GA V+GFQ+V+
Sbjct: 181 RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVD 240
Query: 258 YTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRR 317
Y D++ ++ +++W T + +++ KYTSALTYD V+VM EAF++LR+QRI+ISRR
Sbjct: 241 YDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRR 300
Query: 318 GNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIR 377
GNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F++ G+R NYT++++E+K +G R
Sbjct: 301 GNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPR 360
Query: 378 KIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEG 437
KIGYW+E DK V T+ D S ++ +T +VTTILE PYVM+KKN EGN+RYEG
Sbjct: 361 KIGYWSEVDKMVVTLTE----DDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEG 416
Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITL 497
YCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WNGMVGELVYG+AD+A+APLTITL
Sbjct: 417 YCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITL 476
Query: 498 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 557
VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSVVLFLV
Sbjct: 477 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLV 536
Query: 558 SRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGG 617
SRFSPYEWH+EEFE+G + T NEFGIFNS WF+L F QQG DISPRSLS RIV G
Sbjct: 537 SRFSPYEWHTEEFEDGEEST-----NEFGIFNSFWFALKLFFQQGADISPRSLSARIVAG 591
Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSK 677
VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTL++GSTKEFFRRSK
Sbjct: 592 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK 651
Query: 678 IAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 737
IAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV
Sbjct: 652 IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 711
Query: 738 GGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDK 797
GGNLDSKGYGIATPKGS+L PVNLAVLKLSEQGVLDKLK+KWWYDKGECG+KDSGSK+K
Sbjct: 712 GGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEK 771
Query: 798 TSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842
TSALSLSNVAGVFYIL+GGLGLAMLVALIEF YKSR+E+KRMKG
Sbjct: 772 TSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMKGL 816
>5KUF-A nrPDB
Length = 877
Score = 983 bits (2541), Expect = 0.0, Method: Composition-based stats.
Identities = 347/844 (41%), Positives = 511/844 (60%), Gaps = 42/844 (4%)
Query: 23 NNIQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTY 72
+ ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE +
Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASK 62
Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE- 128
+ C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 63 KACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDF 122
Query: 129 --LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYR 186
L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ +
Sbjct: 123 SSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKD-AK 181
Query: 187 MLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKES 246
L +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ S
Sbjct: 182 PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS 241
Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAE 302
G N+TGF+++N +T + I+++W + + D +AL YD V V++
Sbjct: 242 GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV 301
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRR 361
A Q + + ++ C N PW G +++ +EGLTG + FN+ G R
Sbjct: 302 AVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLR 353
Query: 362 TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDA-QAGGDNSSVQNRTYIVTTILEDPYV 420
T++ L VI +K +G+ KIG W+ + + S+ NR+ IVTTILE+PYV
Sbjct: 354 TDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYV 413
Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNGMV E
Sbjct: 414 LFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRE 473
Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
L+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ +IW
Sbjct: 474 LIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIW 533
Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
M ++ AY+GVSVVLF+++RFSPYEW++ + + N F + NS WF +GA MQ
Sbjct: 534 MYVLLAYLGVSVVLFVIARFSPYEWYNP---HPCNPDSDVVENNFTLLNSFWFGVGALMQ 590
Query: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660
QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQT+I
Sbjct: 591 QGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIE 650
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
YG +E GST FF++SKI+ ++KMW +M S SV V+++EEG+ RV S YA L+ES
Sbjct: 651 YGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYALLMES 708
Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
T E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L +K KW
Sbjct: 709 TTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKW 767
Query: 781 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
W G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ ++ K
Sbjct: 768 WRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEK 823
Query: 841 -GFC 843
FC
Sbjct: 824 RSFC 827
>5IPR-B nrPDB
Length = 825
Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats.
Identities = 185/834 (22%), Positives = 360/834 (43%), Gaps = 125/834 (14%)
Query: 55 LLPQIDIVNI--SDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112
+ P++++V + SD + R C S F + + + V +TP
Sbjct: 59 VTPRVELVTMQESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPI 118
Query: 113 FPVDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQ 159
+ + ++ Q P +++ +++I++ Y W F + G +
Sbjct: 119 LGIHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFE 178
Query: 160 RVLDTAAEKN---WQVTAVNILTTTEEGYRMLFQ-DLEKKKERLVVVDCESERLNAILGQ 215
+ + E + W++ V L + + Q L+K + ++++ C E I
Sbjct: 179 NKVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEV 238
Query: 216 IVKLEKNGIGYHYILANLGFMDID--LNKFKESGANVTGFQLVNYTDTIPARIMQQWRTS 273
+ G G+ +I+ +L D D ++F TG V+Y +W
Sbjct: 239 AHSVGLTGYGFTWIVPSLVAGDTDTVPDEFP------TGLISVSYD---------EW--- 280
Query: 274 DARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQ 333
D+ P A DG+ ++ A ++ + I + ++ + + V +
Sbjct: 281 --------DYDLP----ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YE 326
Query: 334 GIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFVPAA 392
++R L V FEG ++ F+E G + + L +I + ++G + + +
Sbjct: 327 AHMLKRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPV 384
Query: 393 TDAQAGGDNSSVQNRTYIVTTILEDPYVML---------------------KKNANQFEG 431
D + + + T+ E P+V++ + EG
Sbjct: 385 FDLYPNSEEHKDE--HLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEG 442
Query: 432 ND----RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487
+ +G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA
Sbjct: 443 GNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAY 500
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFA 546
+AV LTI R EV+DFS PF+ GIS+M+ + + +FL+P + ++W M V
Sbjct: 501 MAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVML 559
Query: 547 YIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI- 605
I +V +F+ FSP ++ F I ++W G +
Sbjct: 560 LIVSAVAVFVFEYFSPVGYN---------------GPSFTIGKAIWLLWGLVFNNSLPVQ 604
Query: 606 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------I 659
+P+ + +I+ VW FF +I ++SYTANLAAF+ R V + D Q
Sbjct: 605 NPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAF 664
Query: 660 AYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLE 719
+GT+ GST+ R + + +M +YM R+ ++ ++ ++ K A++ +
Sbjct: 665 RFGTVPNGSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYD 715
Query: 720 STMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
+ + Y+ R + C + +G + GYGIA K S + V+LA+L+L G +++L
Sbjct: 716 AAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEEL 775
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
++ W G C + ++ +S L + N+AGVFY+L + L+++ ++E +
Sbjct: 776 EALWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825
>5UOW-A nrPDB
Length = 814
Score = 742 bits (1916), Expect = 0.0, Method: Composition-based stats.
Identities = 213/877 (24%), Positives = 396/877 (45%), Gaps = 131/877 (14%)
Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 77
P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C
Sbjct: 2 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 59
Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125
S VYAI + + LT S+ + V +T + + F+ +
Sbjct: 60 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 119
Query: 126 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 183
P +AL+ ++ + W + I D Q+ L+T E+ + + + + E
Sbjct: 120 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 177
Query: 184 GYRMLFQ---DLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 240
G + L + ++ + R++++ + A+ L+ G GY +++ G +I
Sbjct: 178 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 234
Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVM 300
+ + + + G QL+N K SA D V V+
Sbjct: 235 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 266
Query: 301 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 358
A+A L ++I RG C+ N + W G +R L ++ +G+TG ++FNE
Sbjct: 267 AQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNED 321
Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 411
G R ++ +++ + ++G ++ D K + P + G S + + +
Sbjct: 322 GDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 378
Query: 412 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 442
TI ++P+V ++ + + Y G+CV+L
Sbjct: 379 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDL 438
Query: 443 AAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPLTITLV 498
++A+ + ++Y + +V+DGK+G + + + AWNGM+GEL+ G+AD+ VAPLTI
Sbjct: 439 LIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNE 498
Query: 499 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 558
R + I+FSKPF G++I++KK + + SF+ P +W+ + + V+V+L+L+
Sbjct: 499 RAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 557
Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGG 617
RFSP+ + + + + + + +++WFS + G + +PRS S RI+G
Sbjct: 558 RFSPFG-------RFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGM 610
Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFR 674
VW F +II++SYTANLAAFL + R I D + + Y T++ S +FR
Sbjct: 611 VWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFR 670
Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDT 734
R M+ +M+ + E + VR +K +A++ +S + E+ E + CD
Sbjct: 671 RQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQDCDL 722
Query: 735 MKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGS 794
+ G G+GI K S + V+L +LK E G +++L K W EC S+ +
Sbjct: 723 VTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRSNAP 781
Query: 795 KDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYK 831
+ L+ N+AGVFY++ GG+ + + IE YK
Sbjct: 782 ----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814
>6IRA-D nrPDB
Length = 853
Score = 740 bits (1910), Expect = 0.0, Method: Composition-based stats.
Identities = 193/838 (23%), Positives = 350/838 (41%), Gaps = 114/838 (13%)
Query: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120
++N +D + C S F + + + P +
Sbjct: 73 LMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSHTFVPILGIHGGAS 132
Query: 121 FVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAE 167
++ Q +Q+ ++ I+ Y W F + G + T +
Sbjct: 133 MIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVD 192
Query: 168 KN---WQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGI 224
+ W + V L T+ E + Q L+K ++++ C + IL + L G
Sbjct: 193 NSFVGWDMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGY 251
Query: 225 GYHYILANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVD 282
+ +I+ +L G ++ +F +G V+Y D W S
Sbjct: 252 DFFWIVPSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------- 287
Query: 283 WKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQ 342
A DG+ ++ A S+ + I + C P + +
Sbjct: 288 ------LEARVRDGIGILTTAASSMLEKFSYIPEAKAS--CYGQMERPEVPMHTLHPFMV 339
Query: 343 QVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAAT--DAQAGG 399
V ++G ++ F E+G + + L VI + D K+G W + A ++
Sbjct: 340 NVTWDG--KDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFS 397
Query: 400 DNSSVQNRTYIVTTILEDPYV---------------------MLKKNANQFEG---NDRY 435
D N + T+ E P+V +K N + EG
Sbjct: 398 DCEPDDNH-LSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCC 456
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
+G+C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTI 514
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 554
R EV+DFS PF+ GIS+M+ + + +FL+P + +W M V I ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSRSNGTVSPS-AFLEPFSASVWVMMFVMLLIVSAIAV 573
Query: 555 FLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGR 613
F+ FSP + + +G+ F I ++W G + +P+ + +
Sbjct: 574 FVFEYFSPVGY-NRNLAKGKAP----HGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSK 628
Query: 614 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAG 667
I+ VW FF +I ++SYTANLAAF+ R V + D Q +GT+ G
Sbjct: 629 IMVSVWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNG 688
Query: 668 STKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIE 727
ST+ R + + M YM + E+ ++ ++ K A++ ++ + Y
Sbjct: 689 STERNIRNN----YPYMHQYMTKFNQ----KGVEDALVSLKTGKLD-AFIYDAAVLNYKA 739
Query: 728 QR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784
R + C + +G + GYGIA KGS + ++LA+L+ G +++L++ W
Sbjct: 740 GRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--T 797
Query: 785 GECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF-CYKSRSESKRMKG 841
G C + ++ +S L + N+AGVFY+L + L+++ + E YKSR+E+KRMKG
Sbjct: 798 GIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMKG 853
>4PE5-B nrPDB
Length = 820
Score = 730 bits (1883), Expect = 0.0, Method: Composition-based stats.
Identities = 186/832 (22%), Positives = 352/832 (42%), Gaps = 115/832 (13%)
Query: 55 LLPQIDIVNIS--DSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112
++P++++V ++ D + R C S F + + + +TP
Sbjct: 38 VVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPI 97
Query: 113 FPVDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQ 159
+ + ++ Q P +++ +++I++ Y W F + G
Sbjct: 98 LGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFV 157
Query: 160 RVLDTAAEKN---WQVTAVNILTTT-EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQ 215
+ + E + W++ V +L + ++G + L+K + ++++ C E I
Sbjct: 158 NKIRSTIENSFVGWELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEV 217
Query: 216 IVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDA 275
+ G GY +I+ +L D D + TG V+Y +W
Sbjct: 218 ANSVGLTGYGYTWIVPSLVAGDTDTVPSEFP----TGLISVSYD---------EW----- 259
Query: 276 RDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGI 335
D+ P A DG+ ++ A + + I ++ C Q
Sbjct: 260 ------DYGLP----ARVRDGIAIITTAASDMLSEHSFIPEPKSS--CYNTHEKRIYQSN 307
Query: 336 DIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFVPAATD 394
+ R L V FEG ++ F+E G + + L +I + ++G W + +
Sbjct: 308 MLNRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVW 365
Query: 395 AQAGGDNSSVQNRTYIVTTILEDPYVML-------------------------KKNANQF 429
+ D+ + T+ E P+V++ K +
Sbjct: 366 PRMTQDD------HLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPG 419
Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
+G+C+++ +I+K V ++Y L +V++GK+G + WNGM+GE+V RA +A
Sbjct: 420 YIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKI--NGTWNGMIGEVVMKRAYMA 477
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYI 548
V LTI R EV+DFS PF+ GIS+M+ + + +FL+P + +W M V I
Sbjct: 478 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSACVWVMMFVMLLI 536
Query: 549 GVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SP 607
+V +F+ FSP + + +GR+ F I ++W G + +P
Sbjct: 537 VSAVAVFVFEYFSPVGY-NRSLADGREPG----GPSFTIGKAIWLLWGLVFNNSVPVQNP 591
Query: 608 RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAY 661
+ + +I+ VW FF +I ++SYTANLAAF+ E V + D Q +
Sbjct: 592 KGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRF 651
Query: 662 GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLEST 721
GT+ GST+ R + + +M YM R ++ ++ ++ K A++ ++
Sbjct: 652 GTVPNGSTERNIRNN----YAEMHAYMGKFNQ----RGVDDALLSLKTGKLD-AFIYDAA 702
Query: 722 MNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778
+ Y+ R + C + +G S GYGIA K S + V+LA+L+L G +++L++
Sbjct: 703 VLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEA 762
Query: 779 KWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
W G C + ++ +S L N+AGVFY+L + L+++ + E +
Sbjct: 763 LWL--TGIC--HNEKNEVMSSQLDCDNMAGVFYMLGAAMALSLITFISEHLF 810
>5FXI-A nrPDB
Length = 846
Score = 727 bits (1877), Expect = 0.0, Method: Composition-based stats.
Identities = 211/903 (23%), Positives = 390/903 (43%), Gaps = 150/903 (16%)
Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTEP----PKLLPQIDIVNISDSFEMTYRFCSQ 77
P + IG + ++ ++ FR A++Q + L + + ++ +M C
Sbjct: 2 PKIVNIGAVLSTRKHEQ--MFREAVNQANKRHGSWKIQLQATSVTHKPNAIQMALSVCED 59
Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125
S VYAI + + T S+ + V +T + + F+ +
Sbjct: 60 LISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTV 119
Query: 126 RPELQE--ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEK--------------- 168
P + ++ Y W + + D Q+ L+T E+
Sbjct: 120 PPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKSKKRNYENLDQ 179
Query: 169 ----NWQVTAVNILTTTEEGYRM---LFQDLEKKKERLVVVDCESERLNAILGQIVKLEK 221
N + + + G + L + + + R++++ + + L+
Sbjct: 180 LSYDNKRGPKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDM 239
Query: 222 NGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRV 281
G GY +++ G +I N + + + G QL+N
Sbjct: 240 TGSGYVWLV---GEREISGNALRYAPDGIIGLQLIN------------------------ 272
Query: 282 DWKRPKYTSALTYDGVKVMAEAFQSLRR-QRIDISRRGNAGDCLANPAVPWGQGIDIQRA 340
K SA D V V+A+A L + I RG C+ N + W G +R
Sbjct: 273 ----GKNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRV 323
Query: 341 LQQVRF-EGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAA 392
L ++ +G+TG V+FNE G R ++ +++ + ++G +N D K + P
Sbjct: 324 LMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGG 383
Query: 393 TDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYE---------------- 436
+ G S + + + TI ++P+V +K + + +
Sbjct: 384 ETEKPRGYQMSTRLK---IVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPND 440
Query: 437 ---------------GYCVELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGM 477
G+C++L ++A+ + ++Y + +V+DGK+G + + + K WNGM
Sbjct: 441 TSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGM 500
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537
+GEL+ G+AD+ VAPLTI R + I+FSKPF G++I++KK + + SF+ P
Sbjct: 501 MGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQS 559
Query: 538 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGA 597
+W+ + + V+V+L+L+ RFSP+ + + S+ ++ + +++WFS G
Sbjct: 560 TLWLLVGLSVHVVAVMLYLLDRFSPFG-------RFKVNSQSESTDALTLSSAMWFSWGV 612
Query: 598 FMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
+ G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 613 LLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLR 672
Query: 657 T---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGK 713
+ Y T++ S +FRR M+ +M+ + E + VR +K
Sbjct: 673 NPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL- 725
Query: 714 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVL 773
+A++ +S + E+ E + CD + G G+GI K S + V+L++LK E G +
Sbjct: 726 HAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFM 784
Query: 774 DKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSR 833
+ L K W EC S+ + + L+ N+AGVF ++ GG+ + + IE YK
Sbjct: 785 EDL-DKTWVRYQECDSRSNAP----ATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRH 839
Query: 834 SES 836
++
Sbjct: 840 KDA 842
>5UP2-B nrPDB
Length = 831
Score = 725 bits (1870), Expect = 0.0, Method: Composition-based stats.
Identities = 183/879 (20%), Positives = 354/879 (40%), Gaps = 109/879 (12%)
Query: 4 IFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFA-LSQLTEPPKLLPQIDIV 62
++ F G LG +FP + I + + R ++ + +V
Sbjct: 8 LYTFLYAGDLGHGAEKSFP-VLNIAVILGRTRYITERDIRSLWTRDMSLDFDVNVVTLLV 66
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
+D + C S F + + + P + + +
Sbjct: 67 QQTDPKSIITHVCDLMSGTKIHGVVFGDDTDQEAIAQILDFVSSQTFIPILGIHGGSSMI 126
Query: 123 L----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN 169
+ Q +++ +++I++ Y W F I G + T + +
Sbjct: 127 MADKDEMSTFFQFGASIKQQATVMLNIMEEYDWHVFSVITSNFPGYRDFISFIKTTVDNS 186
Query: 170 ---WQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGY 226
W+V L T+ + L Q L+K ++++ C + I + L G G+
Sbjct: 187 FVGWEVQNYITLDTSYTDAQTLTQ-LKKIHSSVILLYCSKDEATYIFEEARSLGLMGYGF 245
Query: 227 HYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRP 286
+I+ +L + D+ ++ +G V+Y DW
Sbjct: 246 VWIVPSLVTGNTDIIPYEFP----SGLVSVSYD----------------------DWDYG 279
Query: 287 KYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF 346
A DG+ ++ A ++ + I + C + + V +
Sbjct: 280 --IEARVRDGLGIITTAASAMLEKHSVIPEAKTS--CYGQNERNDPPLHTLHNFMINVTW 335
Query: 347 EGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYW-----------------NEDDKF 388
+G ++ F E G + N L V+ + K+G W + DD
Sbjct: 336 DG--KDLSFTEDGYQANPKLVVLLLNMEREWEKVGKWEAKSLNMKYPVWPRIDSDHDDNH 393
Query: 389 VPAATDAQAGGDNSSVQNRTYIVTTILEDP-----YVMLKKNANQFEG-NDRYEGYCVEL 442
+ T +A V+N Y+ T + + Y L + + +G+C+++
Sbjct: 394 LSIVTLEEA--PFVIVENIDYLTGTCVRNTVPCRKYFRLANSTTEGTSVKKCCKGFCIDI 451
Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502
+++K V ++Y L +V++GK+G + + WNGM+GE+VY RA +AV LTI R
Sbjct: 452 LKKLSKTVKFTYDLYLVTNGKHGKKIKN--VWNGMIGEVVYKRAVMAVGSLTINEERSVA 509
Query: 503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 561
+DFS PF+ GIS+M+ + + +FL+P + +W M V + ++ +F+ FS
Sbjct: 510 VDFSVPFVETGISVMVSRSAGTVSPS-AFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFS 568
Query: 562 PYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 620
P + + +G+D F I ++W G + +P+ + +I+ +W
Sbjct: 569 PVGY-NRNLAQGKDP----HGPSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWA 623
Query: 621 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFR 674
FF +I ++SYTANLAAF+ R V + D Q +GT+ GST+ R
Sbjct: 624 FFAVIFLASYTANLAAFMIQRRFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIR 683
Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCD 733
+ + M YM + ++ ++ ++ K A++ ++ + Y+ R + C
Sbjct: 684 NN----YPDMHQYMVKFHQ----KGVQDALVSLKTGKLD-AFIYDAAVLNYMAGRDEGCK 734
Query: 734 TMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791
+ +G + GYGIA KGS + P++LA+L+ G +++L+ W G C
Sbjct: 735 LVTIGSGYIFATTGYGIALQKGSRWKRPIDLALLQFVGDGEMEELEKLWL--TGIC--HT 790
Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 791 EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHLF 829
>5KUH-A nrPDB
Length = 757
Score = 612 bits (1579), Expect = e-175, Method: Composition-based stats.
Identities = 197/601 (32%), Positives = 309/601 (51%), Gaps = 37/601 (6%)
Query: 23 NNIQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTY 72
+ ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE +
Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASK 62
Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE- 128
+ C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 63 KACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDF 122
Query: 129 --LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYR 186
L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ +
Sbjct: 123 SSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKD-AK 181
Query: 187 MLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKES 246
L +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ S
Sbjct: 182 PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS 241
Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAE 302
G N+TGF+++N +T + I+++W + + D +AL YD V V++
Sbjct: 242 GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV 301
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRR 361
A Q + + ++ C N PW G +++ +EGLTG + FN+ G R
Sbjct: 302 AVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLR 353
Query: 362 TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDA-QAGGDNSSVQNRTYIVTTILEDPYV 420
T++ L VI +K +G+ KIG W+ + + S+ NR+ IVTTILE+PYV
Sbjct: 354 TDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYV 413
Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNGMV E
Sbjct: 414 LFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRE 473
Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
L+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K D LA +
Sbjct: 474 LIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKG-----TPIDSADDLAKQTK 528
Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
+ G ++ F S+ S Y+ F R Q+ +S+E GI L M+
Sbjct: 529 IEYGAVEDGSTMTFFKKSKISTYD-KMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLME 587
Query: 601 Q 601
Sbjct: 588 S 588
Score = 273 bits (699), Expect = 2e-73, Method: Composition-based stats.
Identities = 96/220 (43%), Positives = 142/220 (64%), Gaps = 12/220 (5%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PI+SA+DLAKQT+I YG +E GST FF++SKI+ ++KMW +M S SV V+
Sbjct: 509 ILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVK 568
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
++EEG+ RV S YA L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R
Sbjct: 569 SSEEGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 625
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLG 818
+ +A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL
Sbjct: 626 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLV 681
Query: 819 LAMLVALIEFCYKSRSESKRMK-GFCLIPQQSINEAIRTS 857
L++ VA+ EF YKS+ ++ K FC ++ E +R S
Sbjct: 682 LSVFVAVGEFLYKSKKNAQLEKRSFC----SAMVEELRMS 717
>5L2E-A nrPDB
Length = 688
Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats.
Identities = 126/581 (21%), Positives = 255/581 (43%), Gaps = 54/581 (9%)
Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCS 76
+ I IG +F ++ FR A+ L + ++L + V+ ++ F+ C
Sbjct: 4 SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACE 63
Query: 77 QFSKGVYAIFGFYERRTVNMLTSFCGALHVCFI--------TPSFP-----VDTSNQFVL 123
++G+ A+ + L S A+H+ + TP + ++ + L
Sbjct: 64 LMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTL 123
Query: 124 QLRPE--LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT 181
+RP L E ++ ++ Y WQ F+ YD++ + +Q LD +++ V +
Sbjct: 124 SVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNI 183
Query: 182 EEGYRMLF-----QDLEKKKE--RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLG 234
+ LF ++L + ++ R ++ + + ++V+ H+I+ N
Sbjct: 184 NKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEE 243
Query: 235 FMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQ-WRTSDARDHTRVDWKRP-----KY 288
D+D+ + ++ ++ T +P I Q+ +R + T D K P +
Sbjct: 244 INDVDVQELVRR--SIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEI 301
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEG 348
++ YD V ++A AF + R S + C+ + PW G + +++ G
Sbjct: 302 SNLYIYDTVLLLANAFHKKLQDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGVNG 359
Query: 349 LTGNVQFNEKGRRTNYTLHVIEMKH-----DGIRKIGYWNEDDKFVPAATDAQAGGDNSS 403
LTG+++F E G N ++ + G+RK+G WN + TD + +
Sbjct: 360 LTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRG 419
Query: 404 VQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGK 463
V R V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D K
Sbjct: 420 VVLR---VVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHK 474
Query: 464 YGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523
YG+ D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++
Sbjct: 475 YGSPQED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRG-- 531
Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564
L L+ + + + +P+E
Sbjct: 532 ---TSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFE 569
Score = 176 bits (447), Expect = 3e-44, Method: Composition-based stats.
Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAE 692
+ R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + +
Sbjct: 526 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 585
Query: 693 PSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIAT 750
S V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA
Sbjct: 586 GSENNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 643
Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
GS R + +L+L + G +D LK KWW G+C
Sbjct: 644 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 681
>5UN1-G nrPDB
Length = 451
Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats.
Identities = 144/476 (30%), Positives = 243/476 (51%), Gaps = 66/476 (13%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYC 439
+ TI ++P+V ++ + + Y G+C
Sbjct: 5 LKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFC 64
Query: 440 VELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPLTI 495
V+L ++A+ + ++Y + +V+DGK+G + + + AWNGM+GEL+ G+AD+ VAPLTI
Sbjct: 65 VDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTI 124
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555
R + I+FSKPF G++I++KK + + SF+ P +W+ + + V+V+L+
Sbjct: 125 NNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLY 183
Query: 556 LVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRI 614
L+ RFSP+ GR + + + +++WFS + G + +PRS S RI
Sbjct: 184 LLDRFSPF---------GRFE------DALTLSSAMWFSWRVLLNSGLGEGAPRSFSARI 228
Query: 615 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKE 671
+G VW F +II++SYTANLAAFL + R I D + + Y T++ S
Sbjct: 229 LGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDI 288
Query: 672 FFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP 731
+FRR M+ +M+ + E + VR +K +A++ +S + E+ E +
Sbjct: 289 YFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQK 340
Query: 732 CDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791
CD + G G+GI K S + V+L +LK E G +++L K W EC S+
Sbjct: 341 CDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRS 399
Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847
+ + L+ N+AGVF ++ GG+ + + IE YKSR+E+KRMKG ++ Q
Sbjct: 400 NAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLFQ 451
>5UN1-B nrPDB
Length = 448
Score = 485 bits (1249), Expect = e-137, Method: Composition-based stats.
Identities = 135/477 (28%), Positives = 237/477 (49%), Gaps = 68/477 (14%)
Query: 408 TYIVTTILEDPYVML---------------------KKNANQFEGND----RYEGYCVEL 442
+ T+ E P+V++ + EG + +G+C+++
Sbjct: 3 HLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDI 62
Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502
+IAK V ++Y L +V++GK+G + WNGM+GE+V RA +AV LTI R EV
Sbjct: 63 LKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTINEERSEV 120
Query: 503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 561
+DFS PF+ GIS+M+ + + +FL+P + ++W M V I +V +F+ FS
Sbjct: 121 VDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFS 179
Query: 562 PYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 620
P ++ F I ++W G + +P+ + +I+ VW
Sbjct: 180 PVGYN---------------GPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWA 224
Query: 621 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------IAYGTLEAGSTKEFFR 674
FF +I ++SYTANLAAF+ R V + D Q +GT+ GST+ R
Sbjct: 225 FFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIR 284
Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCD 733
+ + +M +YM R+ ++ ++ ++ K A++ ++ + Y+ R + C
Sbjct: 285 NN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDAAVLNYMAGRDEGCK 335
Query: 734 TMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791
+ +G + GYGIA K S + V+LA+L+L G +++L++ W G C +
Sbjct: 336 LVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HN 391
Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF-CYKSRSESKRMKGFCLIPQ 847
++ +S L + N+AGVFY+L + L+++ ++E YKSR+E+KRMKG ++ Q
Sbjct: 392 EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGLEVLFQ 448
>1YAE-A nrPDB
Length = 312
Score = 244 bits (622), Expect = 2e-64, Method: Composition-based stats.
Identities = 95/226 (42%), Positives = 129/226 (57%), Gaps = 21/226 (9%)
Query: 396 QAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYR 455
+ S+ NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y
Sbjct: 2 KPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYE 61
Query: 456 LEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515
+ +V DGKYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGIS
Sbjct: 62 IRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGIS 121
Query: 516 IMIKKPQKSKPGVFSFL--------------------DPLAYEIWMCIVFAYIGVSVVLF 555
I+ +KP + PGVFSFL D LA + + G ++ F
Sbjct: 122 ILYRKPNGTNPGVFSFLNGGSLVPRGSERMESPIDSADDLAKQTKIEYGAVEDGATMTFF 181
Query: 556 LVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQ 601
S+ S Y+ F R Q+ +SNE GI L M+
Sbjct: 182 KKSKISTYD-KMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMES 226
Score = 225 bits (573), Expect = 6e-59, Method: Composition-based stats.
Identities = 79/165 (47%), Positives = 112/165 (67%), Gaps = 7/165 (4%)
Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT 700
ERM SPI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++
Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208
Query: 701 EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPV 760
EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R +
Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265
Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSN 805
+A+L+L E+G L +K KWW G C ++S + SAL + N
Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQN 306
>2XXT-A nrPDB
Length = 261
Score = 228 bits (581), Expect = 8e-60, Method: Composition-based stats.
Identities = 86/197 (43%), Positives = 117/197 (59%), Gaps = 6/197 (3%)
Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464
NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKY
Sbjct: 2 SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKY 61
Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524
GA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K
Sbjct: 62 GAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKG--- 118
Query: 525 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNE 584
D LA + + G ++ F S+ S Y+ F R Q+ +SNE
Sbjct: 119 --TPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYD-KMWAFMSSRRQSVLVKSNE 175
Query: 585 FGIFNSLWFSLGAFMQQ 601
GI L M+
Sbjct: 176 EGIQRVLTSDYAFLMES 192
Score = 217 bits (552), Expect = 2e-56, Method: Composition-based stats.
Identities = 71/151 (47%), Positives = 102/151 (67%), Gaps = 4/151 (2%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V+
Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 172
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
+ EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R
Sbjct: 173 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 229
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
+ +A+L+L E+G L +K KWW G C
Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPE 259
>3FAT-A nrPDB
Length = 260
Score = 228 bits (581), Expect = 9e-60, Method: Composition-based stats.
Identities = 128/147 (87%), Positives = 140/147 (95%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
+ +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT
Sbjct: 114 KKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTA 173
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+LR PVN
Sbjct: 174 EGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVN 233
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGECG 788
LAVLKLSE GVLDKLK+KWWYDKGECG
Sbjct: 234 LAVLKLSEAGVLDKLKNKWWYDKGECG 260
Score = 196 bits (497), Expect = 4e-50, Method: Composition-based stats.
Identities = 98/184 (53%), Positives = 122/184 (66%), Gaps = 6/184 (3%)
Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
RT +VTTI+E PYVM KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGA
Sbjct: 2 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 61
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526
RD DTK WNGMVGELVYG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 62 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKG----- 116
Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFG 586
+ LA + + G + F S+ + YE + + + ++ G
Sbjct: 117 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYE-KMWTYMRSAEPSVFTRTTAEG 175
Query: 587 IFNS 590
+
Sbjct: 176 VARV 179
>5O9A-A nrPDB
Length = 264
Score = 228 bits (580), Expect = 1e-59, Method: Composition-based stats.
Identities = 130/151 (86%), Positives = 142/151 (94%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ + +PIESAEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVR
Sbjct: 113 IMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 172
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
TT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+L
Sbjct: 173 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGN 232
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
VNLAVLKLSEQG+LDKLK+KWWYDKGECGS
Sbjct: 233 AVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 263
Score = 202 bits (513), Expect = 6e-52, Method: Composition-based stats.
Identities = 97/186 (52%), Positives = 122/186 (65%), Gaps = 6/186 (3%)
Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464
N+T +VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKY
Sbjct: 2 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 61
Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524
GARD DTK WNGMVGELVYG+AD+A+APLTIT VREEVIDFSKPFMSLGISIMIKK
Sbjct: 62 GARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKG--- 118
Query: 525 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNE 584
+ L+ + + G + F S+ + ++ + + + ++
Sbjct: 119 --TPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFD-KMWTYMRSAEPSVFVRTTA 175
Query: 585 FGIFNS 590
G+
Sbjct: 176 EGVARV 181
>3DP4-A nrPDB
Length = 278
Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats.
Identities = 126/150 (84%), Positives = 141/150 (94%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ + +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +
Sbjct: 129 IMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 188
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
TT +G+ RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL
Sbjct: 189 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGT 248
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
PVNLAVLKLSEQG+LDKLK+KWWYDKGECG
Sbjct: 249 PVNLAVLKLSEQGILDKLKNKWWYDKGECG 278
Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats.
Identities = 108/203 (53%), Positives = 129/203 (63%), Gaps = 6/203 (2%)
Query: 388 FVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIA 447
VP + D+S NRT +VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIA
Sbjct: 1 LVPRGSAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIA 60
Query: 448 KHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSK 507
KHV Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSK
Sbjct: 61 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 120
Query: 508 PFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHS 567
PFMSLGISIMIKK + LA + + G + F S+ + YE
Sbjct: 121 PFMSLGISIMIKKG-----TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYE-KM 174
Query: 568 EEFEEGRDQTTSDQSNEFGIFNS 590
+ + + + ++ G+
Sbjct: 175 WSYMKSAEPSVFTKTTADGVARV 197
>4MF3-A nrPDB
Length = 261
Score = 225 bits (573), Expect = 6e-59, Method: Composition-based stats.
Identities = 89/199 (44%), Positives = 121/199 (60%), Gaps = 7/199 (3%)
Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462
S+ NRT IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y +++V DG
Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60
Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 522
KYGA++ D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K
Sbjct: 61 KYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKG- 118
Query: 523 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQS 582
D LA + + G ++ F S+ S YE F R QT ++
Sbjct: 119 ----TPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYE-KMWAFMSSRQQTALVRN 173
Query: 583 NEFGIFNSLWFSLGAFMQQ 601
++ GI L M+
Sbjct: 174 SDEGIQRVLTTDYALLMES 192
Score = 214 bits (545), Expect = 1e-55, Method: Composition-based stats.
Identities = 70/152 (46%), Positives = 101/152 (66%), Gaps = 4/152 (2%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PI+SA+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + + VR
Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVR 172
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
++EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R
Sbjct: 173 NSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRD 229
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
+ +A+L+L E+G L +K KWW G C +
Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEE 260
>4IGR-A nrPDB
Length = 258
Score = 216 bits (551), Expect = 3e-56, Method: Composition-based stats.
Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 8/196 (4%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
NR+ IVTT+LE+P+VM +K+ GNDR+EGYC++L E+A +G+SY + +V DGKYG
Sbjct: 5 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYG 64
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525
A+D D WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K
Sbjct: 65 AQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKG---- 119
Query: 526 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585
D LA + + G ++ F S+ S +E F + + ++NE
Sbjct: 120 -TPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFE-KMWAFMSSK-PSALVKNNEE 176
Query: 586 GIFNSLWFSLGAFMQQ 601
GI +L M+
Sbjct: 177 GIQRTLTADYALLMES 192
Score = 205 bits (521), Expect = 8e-53, Method: Composition-based stats.
Identities = 72/150 (48%), Positives = 100/150 (66%), Gaps = 5/150 (3%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ FEKMW +M S++PS V+
Sbjct: 114 ILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVK 172
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
EEG+ R + YA L+EST EYI QR C+ ++GG +DSKGYGI TP GS R
Sbjct: 173 NNEEGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRD 229
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
+ +A+L+L E+ L +K KWW G C
Sbjct: 230 KITIAILQLQEEDKLHIMKEKWWRGSG-CP 258
>5IKB-A nrPDB
Length = 257
Score = 205 bits (522), Expect = 6e-53, Method: Composition-based stats.
Identities = 79/198 (39%), Positives = 116/198 (58%), Gaps = 7/198 (3%)
Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465
N T +VTTILE+PY+MLK N EGNDRYEG+CV++ E+A+ + ++Y++ +V DG YG
Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62
Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525
+ + W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K
Sbjct: 63 VPEAN-GTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKG---- 117
Query: 526 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585
+D LA + + + G S+ F SR+ Y+ + + + +S E
Sbjct: 118 -TPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQ-RMWNYMYSKQPSVFVKSTEE 175
Query: 586 GIFNSLWFSLGAFMQQGC 603
GI L + ++
Sbjct: 176 GIARVLNSNYAFLLESTM 193
Score = 202 bits (514), Expect = 4e-52, Method: Composition-based stats.
Identities = 76/150 (50%), Positives = 101/150 (67%), Gaps = 4/150 (2%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PIES +DLA QT I YGT+ GS+ FF+ S+ +++MW YM S +PSVFV+
Sbjct: 112 ILYRKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVK 171
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
+TEEG+ RV S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R
Sbjct: 172 STEEGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRD 228
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
+LA+L+L E L+ LK KWW + G+C
Sbjct: 229 EFDLAILQLQENNRLEILKRKWW-EGGKCP 257
>5EHM-A nrPDB
Length = 268
Score = 205 bits (520), Expect = 1e-52, Method: Composition-based stats.
Identities = 81/152 (53%), Positives = 106/152 (69%), Gaps = 4/152 (2%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ R +PIESAEDLAKQT I YG L+ GST FFR SKI+ +++MW++M+SA PSVF
Sbjct: 117 ILYRKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTA 176
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
+ EG+ RV K KG YA+L+EST EY+ +R C+ +VGG LD+K YGIATP S R
Sbjct: 177 SNGEGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRT 235
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDK---GEC 787
+N +LKL E+G L LK+KWW +K G+C
Sbjct: 236 AINSVILKLQEEGKLHILKTKWWKEKRGGGKC 267
Score = 191 bits (485), Expect = 1e-48, Method: Composition-based stats.
Identities = 70/190 (36%), Positives = 112/190 (58%), Gaps = 6/190 (3%)
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460
+++++N+T +VTTIL +PY M K++A GND++EGY V+L EI+K +G++Y++++V
Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61
Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K
Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121
Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSD 580
+ LA + + G + F S+ S Y+ F E +
Sbjct: 122 G-----TPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQ-RMWSFMESARPSVFT 175
Query: 581 QSNEFGIFNS 590
SN G+
Sbjct: 176 ASNGEGVERV 185
>5DT6-A nrPDB
Length = 267
Score = 197 bits (501), Expect = 2e-50, Method: Composition-based stats.
Identities = 82/146 (56%), Positives = 105/146 (71%), Gaps = 1/146 (0%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
+ +PI++ EDL QT++ YGTL GST EFFRRS+I + KMW YM A V T +
Sbjct: 122 KKGTPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMN-ANQHHSVHTYD 180
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761
EG+ RVR+SKGKYA L+ES NEY+ R PCDTMKVG N+D+KG+G+ATP GS LR +N
Sbjct: 181 EGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLN 240
Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGEC 787
AVL L E G L ++++KWW+DK EC
Sbjct: 241 EAVLTLKENGELLRIRNKWWFDKTEC 266
Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats.
Identities = 73/190 (38%), Positives = 103/190 (54%), Gaps = 10/190 (5%)
Query: 404 VQNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461
+N TYIV+++LE+PY+ LK+ GNDR+EGYC +LA +A +G Y + +V D
Sbjct: 4 DRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQD 63
Query: 462 GKYGARDPDT-KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
G YGA + W+GMVGEL+ AD+A++ +TIT RE VIDFSKPFM+LGISIMIKK
Sbjct: 64 GNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKK 123
Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSD 580
K + L + + G + F S+ + E +Q S
Sbjct: 124 GTPIKTP-----EDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNA--NQHHSV 176
Query: 581 QSNEFGIFNS 590
+ + GI
Sbjct: 177 HTYDEGIRRV 186
>5CC2-A nrPDB
Length = 265
Score = 175 bits (444), Expect = 6e-44, Method: Composition-based stats.
Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAE 692
+ R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + +
Sbjct: 109 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 168
Query: 693 PSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIAT 750
S V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA
Sbjct: 169 GSENNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 226
Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
GS R + +L+L + G +D LK KWW G+C
Sbjct: 227 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 264
Score = 142 bits (357), Expect = 8e-34, Method: Composition-based stats.
Identities = 42/156 (26%), Positives = 82/156 (52%), Gaps = 8/156 (5%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468
V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D KYG+
Sbjct: 5 LRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQ 62
Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 528
D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++
Sbjct: 63 ED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRG-----TS 116
Query: 529 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564
L L+ + + + +P+E
Sbjct: 117 IQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFE 152
>4WXJ-A nrPDB
Length = 269
Score = 173 bits (437), Expect = 4e-43, Method: Composition-based stats.
Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 1/146 (0%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ + I S DL Q ++ +GT+ G+T +F S W M S +P F +
Sbjct: 120 ILSYKGTDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTK 179
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
EEG+ RV+ SKG YA+L+E+T +Y QR C+ ++G + K YGIA P + R
Sbjct: 180 NNEEGVDRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRS 238
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDK 784
+++ +L+LSE+G L KL++KW+
Sbjct: 239 NLSVGILRLSERGELFKLRNKWFNSN 264
Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats.
Identities = 53/184 (28%), Positives = 83/184 (45%), Gaps = 8/184 (4%)
Query: 409 YIVTTILEDPYVMLKKNAN--QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
Y V T + PY ++ +EGN+R+EGY V+L +A+ + + E V D KYG+
Sbjct: 11 YTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGS 70
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526
D +T W+G++ +L+ A + + LTIT R V+DF+ PFM LGISI+ K
Sbjct: 71 YDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKGTDIGS 130
Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFG 586
L L + + G + V F S + ++NE G
Sbjct: 131 -----LHDLVDQNKVQFGTIRGGATSVYFSESN-DTDNRMAWNKMLSFKPDAFTKNNEEG 184
Query: 587 IFNS 590
+
Sbjct: 185 VDRV 188
>5I2K-B nrPDB
Length = 293
Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats.
Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 639 TVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695
+ + + I D + + Y T++ S +FRR M+ +M+
Sbjct: 149 ILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN--- 203
Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755
+ E + VR +K +A++ +S + E+ E + CD + G G+GI K S
Sbjct: 204 -YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSP 260
Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
+ V+L++LK E G ++ L K W EC S
Sbjct: 261 WKQNVSLSILKSHENGFMEDL-DKTWVRYQECDS 293
Score = 132 bits (333), Expect = 5e-31, Method: Composition-based stats.
Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 43/211 (20%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYE-------------------------------G 437
+ TI ++P+V +K + + + G
Sbjct: 7 LKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYG 66
Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPL 493
+C++L ++A+ + ++Y + +V+DGK+G + + + K WNGM+GEL+ G+AD+ VAPL
Sbjct: 67 FCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPL 126
Query: 494 TITLVREEVIDFSKPFMSLGISIMIKKP------QKS--KPGVFSFLDPLAYEIWMCIVF 545
TI R + I+FSKPF G++I++KK + F+ + + I F
Sbjct: 127 TINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYF 186
Query: 546 AYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQ 576
++ YE +E + RD
Sbjct: 187 RRQVELSTMYRHMEKHNYESAAEAIQAVRDN 217
>5H8N-A nrPDB
Length = 285
Score = 157 bits (397), Expect = 2e-38, Method: Composition-based stats.
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 20/156 (12%)
Query: 643 MVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVF 696
+ + D Q +GT+ GST+ R + + M YM
Sbjct: 141 RGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYMTKFNQ--- 193
Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKG 753
+ E+ ++ ++ K A++ ++ + Y R + C + +G + GYGIA KG
Sbjct: 194 -KGVEDALVSLKTGKLD-AFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKG 251
Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
S + ++LA+L+ G +++L++ W G C +
Sbjct: 252 SPWKRQIDLALLQFVGDGEMEELETLWL--TGICHN 285
Score = 133 bits (335), Expect = 3e-31, Method: Composition-based stats.
Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 27/174 (15%)
Query: 403 SVQNRTYIVTTILEDPYV---------------------MLKKNANQFEG---NDRYEGY 438
S + + T+ E P+V +K N + EG +G+
Sbjct: 2 SPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGF 61
Query: 439 CVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLV 498
C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI
Sbjct: 62 CIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTINEE 119
Query: 499 REEVIDFSKPFMSLGISIMIKKP-QKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551
R EV+DFS PF+ GIS+M+ + Q + F P Y G +
Sbjct: 120 RSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGST 173
>4YKP-A nrPDB
Length = 256
Score = 154 bits (389), Expect = 2e-37, Method: Composition-based stats.
Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 3/161 (1%)
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460
+ ++ R + ++ E P++ EGND + G ++ ++++ +G++Y
Sbjct: 2 SKNLIGRHLRLGSVEEQPFMFFATEG--CEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPD 59
Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
D K+GA + T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K
Sbjct: 60 DRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKG 119
Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS 561
+ V LD Y+ W I + + SR+S
Sbjct: 120 EGTTLNQVLELLDQDKYK-WGVIGSRHPETLLKTHRDSRYS 159
Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 57/149 (38%), Gaps = 9/149 (6%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
V+ + + +L Q + +G + + + + + + + ++ + V ++
Sbjct: 116 VVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRL------VDEGVELK 169
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
+ +R G + ++ E + + CD VG S Y PK S +
Sbjct: 170 DLNHAIETLR--GGLFVFIDEGPVLAHNLISD-CDVFSVGEEFQSFEYAFGLPKDSPYKS 226
Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787
++ +LK E+G +D L KW C
Sbjct: 227 LIDSHLLKFREEGFIDILWEKWSSGNSVC 255
>3OEK-A nrPDB
Length = 286
Score = 144 bits (363), Expect = 2e-34, Method: Composition-based stats.
Identities = 34/156 (21%), Positives = 69/156 (44%), Gaps = 20/156 (12%)
Query: 643 MVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVF 696
+ + D Q + +GT+ GST++ R + + M +YM
Sbjct: 142 RGTTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQ--- 194
Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKG 753
EE + +++ K A++ ++ + Y+ ++ + C + +G + GYGIA KG
Sbjct: 195 -PRVEEALTQLKAGKLD-AFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKG 252
Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
S + P++LA+L+ ++ L+ W G C +
Sbjct: 253 SRWKRPIDLALLQFLGDDEIEMLERLWL--SGICHN 286
Score = 130 bits (327), Expect = 2e-30, Method: Composition-based stats.
Identities = 45/176 (25%), Positives = 76/176 (43%), Gaps = 29/176 (16%)
Query: 403 SVQNRTYIVTTILEDPYVMLKK--------------------------NANQFEGNDRYE 436
+ V T+ E P+V+++ +
Sbjct: 1 GDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCK 60
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496
G+C+++ +A +G+SY L +V++GK+G + WNGM+GE+ Y RAD+A+ LTI
Sbjct: 61 GFCIDILKRLAHTIGFSYDLYLVTNGKHGKKID--GVWNGMIGEVFYQRADMAIGSLTIN 118
Query: 497 LVREEVIDFSKPFMSLGISIMIKKPQK-SKPGVFSFLDPLAYEIWMCIVFAYIGVS 551
R E++DFS PF+ GIS+M+ + S F P + G +
Sbjct: 119 EERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRPQEQYPPLKFGTVPNGST 174
>2RC9-A nrPDB
Length = 294
Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats.
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 13/150 (8%)
Query: 638 LTVERMVSPIESAEDLAKQTE---IAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694
+ V + + D +GT+ S +++ R+S F +M YM+
Sbjct: 147 ILVRTRGTELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQS----FPEMHEYMRRYN-- 200
Query: 695 VFVRTTEEGMIRVRKSKGKY-AYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPK 752
V T +G+ ++ K A++++ + +Y + C + VG +GYGI P
Sbjct: 201 --VPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPP 258
Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
S L ++ + + G +D L KW+
Sbjct: 259 NSPLTSNISELISQYKSHGFMDVLHDKWYK 288
Score = 116 bits (289), Expect = 7e-26, Method: Composition-based stats.
Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 37/156 (23%)
Query: 408 TYIVTTILEDPYVMLKKNAN-----------------------------------QFEGN 432
V T++E P+V ++ + +
Sbjct: 6 HLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFK 65
Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492
GYC++L ++A+ + + + L IV DGKYGA W G+VG+L+ G A++AV
Sbjct: 66 KCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NGHWTGLVGDLLSGTANMAVTS 123
Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 528
+I R +VIDF+ PF S + I+++ G+
Sbjct: 124 FSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGI 159
>5TUJ-C nrPDB
Length = 235
Score = 131 bits (329), Expect = 2e-30, Method: Composition-based stats.
Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 20/156 (12%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+ KN +Y G+ ++LA +AK +G + W+G
Sbjct: 23 KPFSFKDKNG-------QYTGFDIDLAKALAKELGVKVEFVPTT-------------WDG 62
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
++ L G+ D+ ++ +TIT R++ +DFS P+M+ G +I++KK K F L+
Sbjct: 63 IIPALQTGKFDIVMSGMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLNKPD 122
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEE 572
++ + + + ++ +E ++E F+E
Sbjct: 123 VKVAVQLGTTSEQAAKEFLPKAKIRTFENNAEAFQE 158
Score = 53.2 bits (126), Expect = 5e-07, Method: Composition-based stats.
Identities = 36/150 (24%), Positives = 56/150 (37%), Gaps = 22/150 (14%)
Query: 638 LTVERMVSPIESAEDLAK---QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694
L + I+S EDL K + + GT + KEF ++KI FE
Sbjct: 103 LVKKDNADKIKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE------------ 150
Query: 695 VFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753
E V + A + +S + Y ++ P + V + G A KG
Sbjct: 151 ----NNAEAFQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKG 205
Query: 754 SA-LRGPVNLAVLKLSEQGVLDKLKSKWWY 782
L VN + ++ + G DKL KW+
Sbjct: 206 DPELLNWVNNWLKQMKKDGTYDKLYEKWFK 235
>4ZDM-A nrPDB
Length = 261
Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats.
Identities = 31/144 (21%), Positives = 63/144 (43%), Gaps = 2/144 (1%)
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNA-NQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459
++++ + I E P++ Y G VE+ + +++ + ++Y
Sbjct: 2 SNNLNGMHLRLGIIPEMPFISEPSLGCTNIRDPSCYTGVNVEIVSMMSQDLNFTYNFITP 61
Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
D K+G ++ T WNG++ +L+ + D+ V L+ VR+ IDFS M G+ ++K
Sbjct: 62 EDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALSNNAVRKADIDFSLSMMDGGLGALVK 121
Query: 520 KPQKSKPGVFSFLDPLAYEIWMCI 543
L+ Y+ W +
Sbjct: 122 SDGTDLSHPLELLNQDKYQ-WGVV 144
Score = 62.5 bits (150), Expect = 8e-10, Method: Composition-based stats.
Identities = 29/142 (20%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
V+ + + +L Q + +G +++ + + ++ A + ++ AE +V V
Sbjct: 119 LVKSDGTDLSHPLELLNQDKYQWGVVDSRNPELLLASNQNADYNRI------AEDAVKVG 172
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758
+ EG+ R+R G + ++ E Y + CD +++G K S +
Sbjct: 173 SYGEGLERMRA--GGFVFIDEIPGINYAT-KGECDIVQIGETFQPFELAFGLRKNSPFKN 229
Query: 759 PVNLAVLKLSEQGVLDKLKSKW 780
V+ +L + EQGV+ +L +K+
Sbjct: 230 LVDTFMLGIREQGVISELYAKY 251
>3K4U-A nrPDB
Length = 245
Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats.
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 24/157 (15%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
P+ M K N G+ V+LA E+AK +G +L S W+G+
Sbjct: 17 PFEMKDKKGNVI-------GFDVDLAREMAKAMGVKLKLVPTS-------------WDGL 56
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537
+ LV + D+ ++ +TI+ R ++F +P++ +G S+++KK + GV S+ D
Sbjct: 57 IPGLVTEKFDIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEK--GVKSYKDLDKP 114
Query: 538 EIWMCIVFAYIG--VSVVLFLVSRFSPYEWHSEEFEE 572
E+ + F + LF ++ Y+ +E +E
Sbjct: 115 ELTLVTKFGVSAEYAAKRLFKNAKLKTYDTEAEAVQE 151
Score = 41.7 bits (96), Expect = 0.002, Method: Composition-based stats.
Identities = 27/165 (16%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 626 IISSYTANLAAFLTVERMVSPIESAEDLAKQTEI----AYGTLEAGSTKEFFRRSKIAVF 681
+ Y + L + + ++S +DL + E+ +G + K F+ +K+ +
Sbjct: 84 FVEPYIVVGQSLLVKKGLEKGVKSYKDL-DKPELTLVTKFGVSAEYAAKRLFKNAKLKTY 142
Query: 682 EKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMN-EYIEQRKPCDTMKVGGN 740
+ T E + V K ++ + N ++ Q+ + + +
Sbjct: 143 D----------------TEAEAVQEVLNGKADM-FIFDLPFNVAFMAQKGQGYLVHLDTS 185
Query: 741 LDSKGYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784
L + G A KG +N + ++ G D+L +W+ D
Sbjct: 186 LTYEPLGWAIKKGDPDFLNWLNHFLAQIKHDGSYDELYERWFVDT 230
>2RCB-A nrPDB
Length = 292
Score = 120 bits (300), Expect = 4e-27, Method: Composition-based stats.
Identities = 30/150 (20%), Positives = 60/150 (40%), Gaps = 13/150 (8%)
Query: 638 LTVERMVSPIESAEDLAKQTE---IAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694
+ V + + D +GT+ S + + + S F +M +M+
Sbjct: 145 IMVRTRGTELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKAS----FPEMHAHMRRH--- 197
Query: 695 VFVRTTEEGMIRVRKSKGKY-AYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPK 752
TT G+ + K A++++ ++ +Y + C + VG +GYGI P+
Sbjct: 198 -SAPTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQ 256
Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
S L ++ + + G +D L KW+
Sbjct: 257 NSPLTSNLSEFISRYKSSGFIDLLHDKWYK 286
Score = 119 bits (298), Expect = 6e-27, Method: Composition-based stats.
Identities = 58/285 (20%), Positives = 100/285 (35%), Gaps = 48/285 (16%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGN---------------------------------DRY 435
V T++E P+V +++ +
Sbjct: 7 LRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPRTLRRCC 66
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
GYC++L +A+ + + + L IV DGKYGA W G+VG+L+ GRA +AV +I
Sbjct: 67 YGYCIDLLERLAEDLAFDFELYIVGDGKYGALRD--GRWTGLVGDLLAGRAHMAVTSFSI 124
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555
R +V+DF+ PF S + IM++ G+ + S +
Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVRTRGTELSGIH-DPKLHHPSQGFRFGTVWE-SSAEAY 182
Query: 556 LVSRFSPYEWHSEEFEEGRDQ-------TTSDQSNEFGIFNSLWFSLGAFMQQGCDISPR 608
+ + F H + + N F + SL + C +
Sbjct: 183 IKASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSL-LDYEVSIDADCKLLTV 241
Query: 609 SLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 653
I G + L S T+NL+ F++ + I+ D
Sbjct: 242 GKPFAIEG---YGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK 283
>4PSH-A nrPDB
Length = 227
Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats.
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 22/175 (12%)
Query: 402 SSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459
+++R Y++ + D P+ + +N N G+ V+LA EIA+ +G L+IV
Sbjct: 3 DEIKSRGYLLVGLSADFPPFEFVDENGNI-------VGFDVDLAKEIARRLGV--ELKIV 53
Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
++G++ L+ + DV ++ +TIT R++V+ FS P+ G I+++
Sbjct: 54 D-----------MTFDGLIPSLLTKKIDVIISGMTITEERKKVVAFSDPYFDAGQVIVVR 102
Query: 520 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGR 574
K +P + L + + V RF + E + GR
Sbjct: 103 KDSDFRPKTYEDLVGKTVAVQIGTTGDIEVSKYDGIKVVRFDKFTDAFLELKRGR 157
Score = 36.3 bits (82), Expect = 0.058, Method: Composition-based stats.
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 702 EGMIRVRKSKGKYAYL-----------LESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 750
+G+ VR K A+L L+S + P D + G L S+ YGIA
Sbjct: 136 DGIKVVRFDKFTDAFLELKRGRADAVVLDSATARAFVAKNP-DLVISSGVLSSEQYGIAV 194
Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783
K +VL+ ++ D L KW+ +
Sbjct: 195 RKEDTDLLEFINSVLRELKKSPYDVLIEKWFSE 227
>4ZV2-A nrPDB
Length = 233
Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats.
Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 21/157 (13%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
P+ +N + G+ ++LA IAK +G + + ++G+
Sbjct: 22 PFGFKDENG-------KLVGFDIDLAKAIAKKLGVKVEFKPMD-------------FDGI 61
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537
+ L G+ DV +A +TIT R++ +DFS P+ G +I++KK S L
Sbjct: 62 IPALQSGKIDVVIAGMTITEERKKQVDFSDPYFEAGQAIVVKKGNDS-IKSLEDLKGKKV 120
Query: 538 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGR 574
+ + V + ++ SE F+E +
Sbjct: 121 GVQLGSTSEQHVKKVAKDAGVKVKKFDNFSEAFQELK 157
Score = 55.6 bits (132), Expect = 1e-07, Method: Composition-based stats.
Identities = 29/146 (19%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFV 697
+ V++ I+S EDL + G ++++ ++ K+ +
Sbjct: 100 IVVKKGNDSIKSLEDLKGK---KVGVQLGSTSEQHVKKVAKDAGVKVKKF---------- 146
Query: 698 RTTEEGMIRVRKSKGKYAYLLESTM-NEYIEQRKPCDTMKVGGNLDSKGYGIATPKG-SA 755
E ++ + A + ++ + Y++Q VG + YGIA KG S
Sbjct: 147 DNFSEAFQELKSGRVD-AVVTDNAVALAYVKQNPNAGVKIVGETFSGEPYGIAVRKGNSE 205
Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWW 781
L +N A+ ++ + G DK+ KW+
Sbjct: 206 LLEKINKALEEMKKDGTYDKIYEKWF 231
>5JOS-A nrPDB
Length = 247
Score = 104 bits (258), Expect = 2e-22, Method: Composition-based stats.
Identities = 30/166 (18%), Positives = 67/166 (40%), Gaps = 21/166 (12%)
Query: 408 TYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
T V T + P+ + +Y G+ +++A +AK +G +
Sbjct: 24 TLRVGTTGDYKPFSYRDPDG-------QYTGFDIDVAKSLAKSLGVKVEFVPTT------ 70
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526
W ++ +L + D+A+ +T+T R++ DFS P+M+ G + +++K K
Sbjct: 71 -------WPTLMSDLQADKFDIAMGGVTVTPERQKKADFSDPYMTFGKTPLVRKEDADKF 123
Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEE 572
++ + + + ++ + YE + E F+E
Sbjct: 124 KSLEDINRPDVRVAVNPGGTNEKFAREHLKKAKITVYENNVEIFQE 169
Score = 38.2 bits (87), Expect = 0.018, Method: Composition-based stats.
Identities = 31/153 (20%), Positives = 57/153 (37%), Gaps = 28/153 (18%)
Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFR----RSKIAVFE---KMWTYMKS 690
L + +S ED+ + ++ G+ ++F R ++KI V+E +++ + S
Sbjct: 114 LVRKEDADKFKSLEDIN-RPDVRVAVNPGGTNEKFAREHLKKAKITVYENNVEIFQEVAS 172
Query: 691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 750
V + T E + +K G A L++ G
Sbjct: 173 GRADVMITDTVEALYYAKKHPGLAAVLVD-------------------KPFTHSEKGYMM 213
Query: 751 PKG-SALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
PKG VN + ++ +QG +KL KW
Sbjct: 214 PKGDQEFLNYVNQWLDQMKQQGTYEKLYEKWLK 246
>4F3P-A nrPDB
Length = 249
Score = 101 bits (251), Expect = 2e-21, Method: Composition-based stats.
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 21/137 (15%)
Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487
+F+ D+Y G+ ++L AEIAK G++Y+++ + + G++ L D
Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 547
VA++ +TI R + IDFS P+ G++ M++ + + ++ ++ A
Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQANNTTIKSID--------DLNGKVIAAK 136
Query: 548 IGVSVVLFLVSRFSPYE 564
G + + ++ + P E
Sbjct: 137 TGTATIDWIKAHLKPKE 153
Score = 45.5 bits (106), Expect = 1e-04, Method: Composition-based stats.
Identities = 33/154 (21%), Positives = 57/154 (37%), Gaps = 21/154 (13%)
Query: 630 YTANLAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYM 688
Y + LAA V+ + I+S +DL K GT K + +I F
Sbjct: 107 YDSGLAA--MVQANNTTIKSIDDLNGKVIAAKTGTATIDWIKAHLKPKEIRQFP------ 158
Query: 689 KSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV-GGNLDSKGYG 747
++ + + + A + ++ + + +KV G + YG
Sbjct: 159 ----------NIDQAYLALEAGRVDAA-MHDTPNVLFFVNNEGKGRVKVAGAPVSGDKYG 207
Query: 748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781
I PKGS L VN + ++ G K+ KW+
Sbjct: 208 IGFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241
>1GGG-A nrPDB
Length = 226
Score = 97.9 bits (242), Expect = 2e-20, Method: Composition-based stats.
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487
+F+ D Y G+ V+L A IAK + Y L+ + ++G++ L D
Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 531
+A+A +TIT R++ IDFS + G+ +M+K V
Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDL 107
Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 698 RTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKGSA- 755
+ + + ++ A L ++ Y + VG +L+++ YGIA PKGS
Sbjct: 137 PNIDNAYMELGTNRAD-AVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDE 195
Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWW 781
LR VN A+ L E G +++ KW+
Sbjct: 196 LRDKVNGALKTLRENGTYNEIYKKWF 221
>4IO3-A nrPDB
Length = 248
Score = 95.6 bits (236), Expect = 8e-20, Method: Composition-based stats.
Identities = 33/153 (21%), Positives = 63/153 (41%), Gaps = 16/153 (10%)
Query: 639 TVERMVSPIESAEDLAKQTEIAY---GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695
+ R + I+ +DL K +I Y G + ++++ R +
Sbjct: 109 ILMRKGTLIDGMDDL-KNGKIPYNRIGIRIGTAGEDYYLREISGGSRNFYP--------- 158
Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755
+++ +E + ++ ++ EY+ C+ VG + D +GI TPK
Sbjct: 159 -LKSRQEMYDSLLAGIIDVSF-MDIGTAEYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWL 216
Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
+++ +L L E G+LD LK KW+ K C
Sbjct: 217 YAKDLDVNILSLRETGILDNLKKKWFQTKA-CP 248
Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats.
Identities = 23/122 (18%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGND-RYEGYCVELAAEIAKHVGYSYRLEIV 459
++ ++ T + I P+ ++ + N + GY ++L + +G+ +++
Sbjct: 2 SARLKGITLRIGVIESVPFTIVANVIDTSGRNTTKLTGYVLDLIEYLRDKMGFVADVQLA 61
Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
P ++ G+V L G D+A+ +T+T R E++ FS + I+++
Sbjct: 62 ---------PPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNSMRILMR 112
Query: 520 KP 521
K
Sbjct: 113 KG 114
>4H5F-A nrPDB
Length = 243
Score = 91.0 bits (224), Expect = 2e-18, Method: Composition-based stats.
Identities = 28/129 (21%), Positives = 58/129 (44%), Gaps = 17/129 (13%)
Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464
+ + + T+ P+ + +G ++ G +++A IA +G +
Sbjct: 11 KGKLVVATSPDYAPFEF----QSLVDGKNQVVGADIDMAQAIADELGVKLEI-------- 58
Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524
+ +++ ++ L G+AD+AVA ++ T R+EV DFS P+ IS ++ K
Sbjct: 59 -----LSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVHKADVE 113
Query: 525 KPGVFSFLD 533
K + L+
Sbjct: 114 KYKDLTSLE 122
>4YMX-A nrPDB
Length = 260
Score = 85.2 bits (209), Expect = 1e-16, Method: Composition-based stats.
Identities = 29/138 (21%), Positives = 54/138 (39%), Gaps = 21/138 (15%)
Query: 397 AGGDNSSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSY 454
++ + IV D P+ K G D G+ +++A IAK +G
Sbjct: 26 KFNTVDQIKQKGVIVMGTSADFPPFEFHKVEG----GKDEIVGFDIDIANAIAKKLGVKL 81
Query: 455 RLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514
++ + + G++ L GR D+ +A +T T R++ +DFS +
Sbjct: 82 EIKDMD-------------FKGLIPALQAGRVDMVIAGMTPTAERKKSVDFSDLYYDSRQ 128
Query: 515 SIMIKKPQKSKPGVFSFL 532
+++K S F L
Sbjct: 129 VVVVK--NDSPISKFDDL 144
Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats.
Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 26/152 (17%)
Query: 638 LTVERMVSPIESAEDLAKQT-EIAYGTLEAGSTKE--FFRRSKIAVFEKMWTYMKSAEPS 694
+ V + SPI +DL +T + GT + K+ + ++ +M
Sbjct: 129 VVVVKNDSPISKFDDLKVKTIAVQIGTTSEEAAKKIPNVKLKQLNRVSD--EFMDLQNGR 186
Query: 695 VFVRTTEEGMIR--VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPK 752
E+ + + +++ K ++ N G +A K
Sbjct: 187 CDAIVVEDTVAKAYLKEYKDMKILYMDEINN------------------VENGSAVAVAK 228
Query: 753 GS-ALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783
G+ +L VN + +L + G DKL KW+
Sbjct: 229 GNKSLLDVVNEVIKELKQSGEYDKLVDKWFKQ 260
>4G4P-A nrPDB
Length = 244
Score = 83.7 bits (205), Expect = 3e-16, Method: Composition-based stats.
Identities = 32/175 (18%), Positives = 63/175 (36%), Gaps = 29/175 (16%)
Query: 400 DNSSVQNRTYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEI 458
++ + Y + T L P+ +Y G V+L IAK + L+
Sbjct: 16 YFQGMEGKKYTIGTDLTFAPFEFQDSKG-------KYIGIDVDLLDAIAKDQDFEVDLKP 68
Query: 459 VSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMI 518
+ ++ V + + D +A ++IT R++ DFS P+ G+ + +
Sbjct: 69 LG-------------FDSAVQAIQSKQIDGMIAGMSITDERKKSFDFSDPYFDSGLQLAV 115
Query: 519 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573
KK ++ V A +G FL Y++ + F++
Sbjct: 116 KKGNDKIKSYD--------DLKGKTVAAKVGTESANFLEKNKEKYDYTIKNFDDA 162
>4I62-A nrPDB
Length = 269
Score = 80.6 bits (197), Expect = 3e-15, Method: Composition-based stats.
Identities = 28/133 (21%), Positives = 61/133 (45%), Gaps = 19/133 (14%)
Query: 402 SSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459
+++++ +V + D P+ K +G ++ G +ELA IA +G L +
Sbjct: 33 EAIKSKGKLVVALNPDFAPFEYQK----VVDGKNQIVGSDIELAKAIATELGVELELSPM 88
Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
S ++ ++ + G+AD+A++ ++ T R +V DFS P+ + +++K
Sbjct: 89 S-------------FDNVLASVQSGKADLAISGVSKTDERSKVFDFSTPYYTAKNKLIVK 135
Query: 520 KPQKSKPGVFSFL 532
K + + L
Sbjct: 136 KSDLATYQSVNDL 148
Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats.
Identities = 46/237 (19%), Positives = 93/237 (39%), Gaps = 31/237 (13%)
Query: 552 VVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLS 611
+V+ L F+P+E+ ++ +G++Q ++ + ++ LG ++SP S
Sbjct: 41 LVVALNPDFAPFEY--QKVVDGKNQIV---GSDIELAKAIATELGV----ELELSPMSFD 91
Query: 612 GRIVGGVWWFFTLIIISSYTANLAAFLTVER-----MVSPIESAEDL---AKQTEIAYGT 663
++ V + IS + T ER +P +A++ K Y +
Sbjct: 92 N-VLASVQSGKADLAISGVSK------TDERSKVFDFSTPYYTAKNKLIVKKSDLATYQS 144
Query: 664 LEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMN 723
+ + K+ K ++ E M + V + + ++ + A + E +
Sbjct: 145 VNDLAQKK-VGAQKGSIQETMAKDLLQNSSLVSLPKNGNLITDLKSGQVD-AVIFEEPVA 202
Query: 724 EYIEQRKPCDTMKVGGNLDSK---GYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKL 776
+ + P D N + + Y +A K S L+ V+ + KL E G LDKL
Sbjct: 203 KGFVENNP-DLAIADLNFEKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKL 258
>2Q2A-A nrPDB
Length = 272
Score = 79.1 bits (193), Expect = 9e-15, Method: Composition-based stats.
Identities = 23/113 (20%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+ ++K + G+ V+L + K G Y L+ W+
Sbjct: 53 APFEYMQK--------GKIVGFDVDLLDAVMKAAGLDYELK-------------NIGWDP 91
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
+ L D+ ++ +TIT R++ DFS P+ I++K+ K +
Sbjct: 92 LFASLQSKEVDMGISGITITDERKQSYDFSDPYFEATQVILVKQGSPVKNALD 144
Score = 49.0 bits (115), Expect = 1e-05, Method: Composition-based stats.
Identities = 29/151 (19%), Positives = 63/151 (41%), Gaps = 20/151 (13%)
Query: 635 AAFLTVERMVSPIESAEDLAKQT-EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEP 693
A + + + SP+++A DL +T + T + ++ F + ++K E
Sbjct: 127 ATQVILVKQGSPVKNALDLKGKTIGVQNATTGQEAAEKLFGKG---------PHIKKFET 177
Query: 694 SVFVRTTEEGMIRVRKSKGKYAYLLESTM-NEYIEQRKPCDTMKVG--GNLDSKGYGIAT 750
+V ++ + A + ++ + NEY++ + N S+ YG+
Sbjct: 178 TVV------AIMELLNGGVD-AVITDNAVANEYVKNNPNKKLQVIEDPKNFASEYYGMIF 230
Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781
PK S L+ V+ A+ + G ++ KW+
Sbjct: 231 PKNSELKAKVDEALKNVINSGKYTEIYKKWF 261
>4ZEF-A nrPDB
Length = 251
Score = 73.7 bits (179), Expect = 3e-13, Method: Composition-based stats.
Identities = 34/179 (18%), Positives = 60/179 (33%), Gaps = 28/179 (15%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+ + Y G V+L A+ G++ + + ++
Sbjct: 39 APFEFQNAQGD-------YVGIDVDLVKRAAELQGFTVEFKFIG-------------FSS 78
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
V + G+AD VA +TIT R++ DFS P+ GI I +KK + S+ D
Sbjct: 79 AVQAVESGQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKKGND---KIKSYDDLKG 135
Query: 537 YEIWMCIV-----FAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNS 590
++ + I F + + + E G D G +
Sbjct: 136 KKVGVKIGTESADFLEKNKKKYDYSIKYLDTTDALYSALEIGEVDAMMDDYPVIGYGVA 194
>2PYY-A nrPDB
Length = 228
Score = 69.8 bits (169), Expect = 5e-12, Method: Composition-based stats.
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 687 YMKSAEPSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSK 744
Y++ SV V EE ++ K A + ++ + + + VG L +
Sbjct: 126 YLREHHISVLEVPKIEEAYKALQTKKAD-AVVFDAPVLLFYAANEGKGKVEIVGSILREE 184
Query: 745 GYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784
YGI P S R P+N A+L L E G L KW+ K
Sbjct: 185 SYGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWFDPK 224
Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats.
Identities = 23/111 (20%), Positives = 47/111 (42%), Gaps = 20/111 (18%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468
+V T + P+V G+ ++L IA +G +L +Y +
Sbjct: 5 LLVATRVIPPFV--------LSNKGELSGFSIDLWRSIATQIGIESKLI-----EYSSVP 51
Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
++ + + ++ +A ++IT RE+ DFS P + G+ IM++
Sbjct: 52 E-------LISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95
>5HPQ-A nrPDB
Length = 255
Score = 69.0 bits (167), Expect = 9e-12, Method: Composition-based stats.
Identities = 22/125 (17%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
+ TT P+ + Y G+ V++A +A+ +G + S
Sbjct: 27 VATTGDYKPFSYRTEEG-------GYAGFDVDMAQRLAESLGAKLVVVPTS--------- 70
Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
W ++ + R D+A++ ++I L R+ FS P++ G + + ++++
Sbjct: 71 ----WPNLMRDFADDRFDIAMSGISINLERQRQAYFSIPYLRDGKTPITLCSEEARFQTL 126
Query: 530 SFLDP 534
+D
Sbjct: 127 EQIDQ 131
>5X2N-B nrPDB
Length = 478
Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 53/455 (11%), Positives = 137/455 (30%), Gaps = 98/455 (21%)
Query: 20 NFPNNIQIGGLFPNQQSQEH------------------------AAFRFALSQLTEPPKL 55
+ P +I++GGLFP ++ ++A+ ++ +L
Sbjct: 14 SMPGDIKLGGLFPIKEQSNEVSNDLTKLNSVSCDSLNKDGLGRALVMKYAVEEINANSQL 73
Query: 56 LPQID----------------------IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRT 93
LP + + S+ + + + A+ G
Sbjct: 74 LPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVECNYTDYETDMVAVIGPQSSEM 133
Query: 94 VNMLTSFCGALHVCFITPSFPVDTSN------QFVLQLRPELQE--ALISIIDHYKWQTF 145
V ++ G + I+ D + F + ++++ A++ +I + W
Sbjct: 134 VTVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVPSDIRQVDAMVQLIKKFNWNWV 193
Query: 146 VYI-YDADRGLSVLQRVLDTAAEKNWQVTAVNIL---TTTEEGYRMLFQDLEKKKERLVV 201
+ + + G +Q+ A + V ++ + + + +++ + ++VV
Sbjct: 194 AVVGSEEEYGQQGVQQFSKKAEDMGVCVAYQGLIPIYDDPKPAIQTIINNIQTTEVKVVV 253
Query: 202 VDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKE--SGANVTGFQLVNYT 259
V + +++K G +I ++ + + S V GF T
Sbjct: 254 VFSLVSPAVSFFEEVIKKNLTG---VWIASSSWAISDKVYSLPNIDSIGTVIGFIDETET 310
Query: 260 DTIPARIMQQWRTSDARDHTRVDWKRPKY-----------------------TSALTYDG 296
+ + + + P T+ Y
Sbjct: 311 LELLSPFTEVLFKKIHEASPTEKPEDPYNPCPECWSLSPANVSLVKEESVQRTAFSVYAA 370
Query: 297 VKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFN 356
V +A A L + ++ PW + L++ +++F+
Sbjct: 371 VYTVAHALHKLLECNSAACKWSSSTRLY-----PWK----LLEVLKEFSVNISNTSLKFD 421
Query: 357 EKGRRTNYTLHVIE--MKHDGIRKIGYWNEDDKFV 389
+ G N VI+ ++ + +G + + +
Sbjct: 422 QNG-NPNIGYSVIQRIWENQSLSSVGSYRSANLSI 455
>4OEN-A nrPDB
Length = 223
Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 30/157 (19%), Positives = 59/157 (37%), Gaps = 29/157 (18%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+V + ++Y G +EL IAK G+ + ++
Sbjct: 14 APFVFQNSS-------NQYTGIDMELIKAIAKDQGFEIEI-------------TNPGFDA 53
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
+ + G+AD +A +++T R+ DFS+ + + + +K + S+ D
Sbjct: 54 AISAVQAGQADGIIAGMSVTDARKATFDFSESYYTANTILGVK----ESSNIASYED--- 106
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573
+ V G + FL S Y + + F +G
Sbjct: 107 --LKGKTVGVKNGTASQTFLTENQSKYGYKIKTFADG 141
>4KPT-A nrPDB
Length = 251
Score = 66.0 bits (159), Expect = 7e-11, Method: Composition-based stats.
Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 22/143 (15%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G ++ G V++ E+AK + + ++ + L G+ D +
Sbjct: 46 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 92
Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 550
A +TIT R+E DFS P+ + ++I K K ++ V A G
Sbjct: 93 AGMTITDERKETFDFSNPYYTSALTIATTKDSKLS---------DYSDLKGKAVGAKNGT 143
Query: 551 SVVLFLVSRFSPYEWHSEEFEEG 573
+ +L Y + + + +G
Sbjct: 144 AAQTWLQENQKKYGYTIKTYSDG 166
>6FXG-A nrPDB
Length = 227
Score = 65.6 bits (158), Expect = 8e-11, Method: Composition-based stats.
Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 22/143 (15%)
Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
G ++ G V++ E+AK + + ++ + L G+ D +
Sbjct: 22 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 68
Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 550
A +TIT R+E DFS P+ + ++I K K ++ V A G
Sbjct: 69 AGMTITDERKETFDFSNPYYTSALTIATTKDSKLS---------DYSDLKGKAVGAKNGT 119
Query: 551 SVVLFLVSRFSPYEWHSEEFEEG 573
+ +L Y + + + +G
Sbjct: 120 AAQTWLQENQKKYGYTIKTYSDG 142
>5EYF-A nrPDB
Length = 245
Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats.
Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 15/109 (13%)
Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495
+G+ V++A I K + + +GK + +K + L G D +A +TI
Sbjct: 39 QGFDVDIAKAITKKI-------LGDNGKTEFVEVTSKT---RIPLLKNGNIDAIIATMTI 88
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 544
T R++ +DFS + G ++++KK + K +D L + V
Sbjct: 89 TDERKKQVDFSDVYFDAGQALLVKKGSQIKS-----VDDLNASTTVLAV 132
Score = 53.2 bits (126), Expect = 5e-07, Method: Composition-based stats.
Identities = 30/146 (20%), Positives = 57/146 (39%), Gaps = 17/146 (11%)
Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701
+ S I+S +DL T + ++ ++ R+ + +
Sbjct: 112 KKGSQIKSVDDLNASTTVL--AVKGSTSAANIRQHAPDA------------KILELENYA 157
Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA-LRGPV 760
E ++ +G A ++ + I P + VGG ++ YGIA KG V
Sbjct: 158 EAFTALQSGQGD-AMTTDNAILLGIADENP-EYELVGGTFTNEPYGIAINKGQENFLKAV 215
Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGE 786
N A+ ++ G DK+ KW+ ++ E
Sbjct: 216 NQALEEMHADGTYDKIYQKWFPNETE 241
>4F3S-A nrPDB
Length = 255
Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 37/180 (20%), Positives = 72/180 (40%), Gaps = 27/180 (15%)
Query: 402 SSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461
S V+ RT V P ++ K + +G +EL + +
Sbjct: 4 SIVEGRTLNVAVSPASPPMLFKSAD------GKLQGIDLELFSSYCQS------------ 45
Query: 462 GKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 521
++ + AW+GM+G + G+ADVA + ++IT R++VIDFS+P+ ++
Sbjct: 46 -RHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSF-YLVSMA 103
Query: 522 QKSKPGVFSFLDPLAYEIWMCIVFAY------IGVSVVLFLVSRFSPYEWHSEEFEEGRD 575
K + + + Y I AY + +S+ Y ++E + ++
Sbjct: 104 N-HKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKN 162
Score = 35.1 bits (79), Expect = 0.15, Method: Composition-based stats.
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK-PCDTMKVGGNLDSKGYGIATPKGS 754
T E M ++ A++ E + ++K P ++ V N+D GIA KGS
Sbjct: 149 LYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQ--LGIAFKKGS 206
Query: 755 ALRGPVNLAVLKLSEQG 771
+R N L L EQG
Sbjct: 207 PVRDDFN---LWLKEQG 220
>4MS4-A nrPDB
Length = 420
Score = 62.1 bits (149), Expect = 9e-10, Method: Composition-based stats.
Identities = 68/413 (16%), Positives = 134/413 (32%), Gaps = 45/413 (10%)
Query: 23 NNIQIGGLFPNQQ-----SQEHAAFRFALSQLTEPPKLLPQIDIVNIS-----DSFEMTY 72
+ IG LFP A AL + +LP ++ I D + T
Sbjct: 4 RAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK 63
Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCG------ALHVCFITPSFPVDTSNQFVLQLR 126
I +V+ L + L +P+ +
Sbjct: 64 YLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTH 123
Query: 127 PEL---QEALISIIDHYKWQTFVYIY-DADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE 182
P + + + + W+ I + S L + + E ++T +
Sbjct: 124 PSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQ---SFF 180
Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFM------ 236
+ ++L+++ R++V + ++ K G Y + L
Sbjct: 181 SDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIY 240
Query: 237 ----DIDLNKFKESGANVTGFQLV----NYTDTIPARIMQQWRTSDARDHTRVDWKRPKY 288
+ +++ E+ ++V T +I Q++ + R + +
Sbjct: 241 DPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGF 300
Query: 289 TSA-LTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
A L YD + +A A + S N + I RA+ FE
Sbjct: 301 QEAPLAYDAIWALALAL-NKTSGGGGRSGVRLEDFNYNNQTITDQ----IYRAMNSSSFE 355
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE-DDKFVPAATDAQAGG 399
G++G+V F+ G R +TL + +++ +KIGY++ D + TD GG
Sbjct: 356 GVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGG 407
>5X2M-A nrPDB
Length = 461
Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 67/430 (15%), Positives = 126/430 (29%), Gaps = 89/430 (20%)
Query: 16 VVGANF--PNNIQIGG-LFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTY 72
V ANF P I LF + RF++ ++ LLP + + F+
Sbjct: 26 VAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSL--GYQMFD--- 80
Query: 73 RFCSQFSK--GVYAIFGFYE--RRTVNMLTSFCGALHVCF---------ITPSFPVDTSN 119
CS G++ + + R + T A+ V I P F +
Sbjct: 81 -HCSDIHSFPGIFKLLSVNDLIRPWEDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLFP 139
Query: 120 ------------------QFVLQLR--PELQEALISIIDHYKWQTFVYIYDADRGLSVLQ 159
F+ + ++ A++ II ++ W+ ++Y D
Sbjct: 140 MVSYGCSGSVFSKENLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGL 199
Query: 160 RVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKL 219
E + A Y +F+ +E++ +++VV A++ V+L
Sbjct: 200 EQFKNKIEDSEICLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQL 259
Query: 220 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHT 279
+I D + ++ G Q + + ++ +D
Sbjct: 260 NVTNK--VWI-------ADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSA 310
Query: 280 RVDWKRPKYTSAL--------------------------TYDGVKVMAEAFQSLRRQRID 313
+ Y V +A A +
Sbjct: 311 ISQTDGGDTEQKMFCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTL----- 365
Query: 314 ISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH 373
R + C N V I L++ F L VQF+E G +L V+
Sbjct: 366 ---RCGSDRCPKNITV---HPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVVFWNS 419
Query: 374 DG-IRKIGYW 382
G ++G +
Sbjct: 420 SGNAEEVGSY 429
>4F11-A nrPDB
Length = 433
Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 45/311 (14%), Positives = 102/311 (32%), Gaps = 30/311 (9%)
Query: 104 LHVCFITPSFPVDTSNQFVLQLRPE---LQEALISIIDHYKWQTFVYIYDADRGLSVLQR 160
L TP + + P + A++ ++ HY+W+ + + S ++
Sbjct: 113 LSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRN 172
Query: 161 VLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLE 220
L T + + + + + + L+ R+++ + + +
Sbjct: 173 DL-TGVLYGEDIEISDTESFSND-PCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEEN 230
Query: 221 KNGIGYHYILANLGFMDIDLNKFKESGAN------------VTGFQLVNYT---DTIPAR 265
G Y +I+ G+ + + + AN + G+ V++
Sbjct: 231 MYGSKYQWIIP--GWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKT 288
Query: 266 IMQQWRTSDARDHTRVDWKR-PKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCL 324
I + R++ P YDG+ V+A ++ ++ + +
Sbjct: 289 ISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIA----KTLQRAMETLHASSRHQRI 344
Query: 325 ANPAVPWGQ-GIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWN 383
+ G I A+ + F G+TG V F G R T+ + + K+G +N
Sbjct: 345 QDFNYTDHTLGRIILNAMNETNFFGVTGQVVF-RNGERMG-TIKFTQFQDSREVKVGEYN 402
Query: 384 EDDKFVPAATD 394
+ D
Sbjct: 403 AVADTLEIIND 413
>4KQP-A nrPDB
Length = 232
Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 25/142 (17%), Positives = 54/142 (38%), Gaps = 21/142 (14%)
Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491
+ ++ G V+L IAK+ G+ + + + V + G AD ++
Sbjct: 27 DKQFTGIDVDLLNAIAKNQGFKLKWNFIG-------------FQAAVDSVQSGHADGMMS 73
Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551
++IT R++V D+ P+ S ++I S ++ + A G +
Sbjct: 74 GMSITDARKQVFDYGSPYYSSNLTIATSSTDDSIKSW--------KDLKGKTLGAKNGTA 125
Query: 552 VVLFLVSRFSPYEWHSEEFEEG 573
+L + Y + + F +
Sbjct: 126 SFDYLNAHAKEYGYTVKTFTDA 147
>3TQL-A nrPDB
Length = 227
Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats.
Identities = 18/103 (17%), Positives = 41/103 (39%), Gaps = 20/103 (19%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
PYV + + + EG+ ++ + K + + + W+ +
Sbjct: 14 PYVYMGPSG-------QVEGFGADIVKAVCKQMQAVCTI-------------SNQPWDSL 53
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
+ L G+ D + IT R++ +DF+ P+ + +S + K
Sbjct: 54 IPSLKLGKFDALFGGMNITTARQKEVDFTDPYYTNSVSFIADK 96
>2IEE-A nrPDB
Length = 271
Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats.
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 426 ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGR 485
+ G+D+ GY VE+ E AK +G + + +GM+ + G+
Sbjct: 37 HDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMGI-------------DGMLTAVNSGQ 83
Query: 486 ADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532
D A + +T REE FS P+ + +++K S L
Sbjct: 84 VDAAANDIDVTKDREEKFAFSTPYKYSYGTAIVRKDDLSGIKTLKDL 130
>5OTA-A nrPDB
Length = 265
Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats.
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 13/88 (14%)
Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
+ + G+ ++L ++ K + + +AW+G++ L GR D
Sbjct: 22 DAGGKLIGFDIDLGNDLCKRMNIECKF-------------VEQAWDGIIPSLTAGRYDAI 68
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIM 517
+A + I RE+VI FS+P++ ++ +
Sbjct: 69 MAAMGIQPAREKVIAFSRPYLLTPMTFL 96
>2Y7I-A nrPDB
Length = 229
Score = 59.8 bits (143), Expect = 6e-09, Method: Composition-based stats.
Identities = 21/118 (17%), Positives = 50/118 (42%), Gaps = 22/118 (18%)
Query: 402 SSVQNRTYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460
+SV RT T PY + +++ G+ +++A + K +
Sbjct: 1 ASVSARTLHFGTSATYAPYEFVD-------ADNKIVGFDIDVANAVCKEMQAECSF---- 49
Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMI 518
++++ ++ L + + D +A + +T RE+ + FS+P+ G+S ++
Sbjct: 50 ---------TNQSFDSLIPSLRFKKFDAVIAGMDMTPKREQQVSFSQPYYE-GLSAVV 97
>3VV5-A nrPDB
Length = 260
Score = 59.0 bits (141), Expect = 9e-09, Method: Composition-based stats.
Identities = 23/146 (15%), Positives = 56/146 (38%), Gaps = 18/146 (12%)
Query: 427 NQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRA 486
N F+ ++ G+ V+L IA+ +G ++++ ++ +L GR
Sbjct: 50 NYFDERNQLTGFEVDLGNAIAERLGLK-------------PRWIAQSFDTLLIQLNQGRF 96
Query: 487 DVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 546
D +A IT R +DF+ P G +++ + + D + + +
Sbjct: 97 DFVIASHGITEERARAVDFTNPHYCTG-GVIVSRKGGPRTA----KDLQGKVVGVQVGTT 151
Query: 547 YIGVSVVLFLVSRFSPYEWHSEEFEE 572
Y+ + + + Y+ + ++
Sbjct: 152 YMEAAQKIPGIKEVRTYQRDPDALQD 177
Score = 37.4 bits (85), Expect = 0.031, Method: Composition-based stats.
Identities = 22/109 (20%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 686 TYMKSAEPSVFVRTT------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG 739
TYM++A+ ++ + + + + E I++RK +T++VG
Sbjct: 151 TYMEAAQKIPGIKEVRTYQRDPDALQDLLAGRIDTWITDRFVAKEAIKERKLENTLQVGE 210
Query: 740 NLDSKGYGIATPKGS-ALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787
+ + +A KG+ +L +N A+ +L + G ++ KW+ + C
Sbjct: 211 LVFQERVAMAVAKGNKSLLDALNRALAELMQDGTYARISQKWFGEDVRC 259
>5K5S-A nrPDB
Length = 615
Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats.
Identities = 38/290 (13%), Positives = 99/290 (34%), Gaps = 39/290 (13%)
Query: 44 FALSQLTEPPKLLPQIDI--------VNISDSFEMTYRF----------------CSQFS 79
FA+ ++ P LLP + + +S + E T F CS+
Sbjct: 76 FAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHI 135
Query: 80 KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV------DTSNQFVLQLRPELQEA- 132
A+ G + + G ++ ++ + + F+ + + +A
Sbjct: 136 PSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQAT 195
Query: 133 -LISIIDHYKWQTF-VYIYDADRGLSVLQRVLDTAAEKN--WQVTAVNILTTTEEGYRML 188
+ II++++W D D G +++ + A E++ + + + EE + +
Sbjct: 196 AMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHV 255
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMD--IDLNKFKES 246
+ ++ +++VV L ++ +IV+ G ++ + I + ++
Sbjct: 256 VEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHV 313
Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDG 296
GF L +++ + + + + +G
Sbjct: 314 VGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEG 363
>5FBH-B nrPDB
Length = 568
Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats.
Identities = 38/290 (13%), Positives = 99/290 (34%), Gaps = 39/290 (13%)
Query: 44 FALSQLTEPPKLLPQIDI--------VNISDSFEMTYRF----------------CSQFS 79
FA+ ++ P LLP + + +S + E T F CS+
Sbjct: 103 FAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHI 162
Query: 80 KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV------DTSNQFVLQLRPELQEA- 132
A+ G + + G ++ ++ + + F+ + + +A
Sbjct: 163 PSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQAT 222
Query: 133 -LISIIDHYKWQTF-VYIYDADRGLSVLQRVLDTAAEKN--WQVTAVNILTTTEEGYRML 188
+ II++++W D D G +++ + A E++ + + + EE + +
Sbjct: 223 AMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHV 282
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMD--IDLNKFKES 246
+ ++ +++VV L ++ +IV+ G ++ + I + ++
Sbjct: 283 VEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHV 340
Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDG 296
GF L +++ + + + + +G
Sbjct: 341 VGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEG 390
>5LOM-A nrPDB
Length = 269
Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats.
Identities = 28/139 (20%), Positives = 57/139 (41%), Gaps = 20/139 (14%)
Query: 387 KFVPAATDAQAGGDNSSVQNRTYIVTTI-LEDPYVMLKKNANQFEGNDRYEGYCVELAAE 445
VP + + T V T+ PY + N + G+ +EL
Sbjct: 13 GLVPRGS--HMDNPLGLIDPTTISVGTMGDAKPYAFTTADGN-------FTGFDIELFLN 63
Query: 446 IAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDF 505
+A +G+ ++V G+ ++ ++ + GR DVA A + T R+E +DF
Sbjct: 64 VAGRLGFKKE-QVVFTGQ---------EFSALMPSVANGRFDVAAAAIGTTAKRKETVDF 113
Query: 506 SKPFMSLGISIMIKKPQKS 524
S +++ +S++ + +
Sbjct: 114 SDGYLAGFLSVLTSEAGIT 132
Score = 35.5 bits (80), Expect = 0.12, Method: Composition-based stats.
Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 19/153 (12%)
Query: 634 LAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAE 692
LA FL+V + I A L K+ + GTL+ ++ F + + F
Sbjct: 118 LAGFLSVLTSEAGITDAAGLKGKRLGVVQGTLQEIYAEKNFAGTDLVKFPD--------- 168
Query: 693 PSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPK 752
+ + +L +Y + + D+ G K
Sbjct: 169 -------NNSAVSALNNGTVDAHFLDFEAAKDYSARYPALKIAVNIPSFDAPA-GFVIRK 220
Query: 753 GSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784
G+ LR ++ + + + G KL KW+
Sbjct: 221 GNDALRNALDKGLKEAMQDGTWKKLHEKWFPGT 253
>5ORE-A nrPDB
Length = 263
Score = 57.5 bits (137), Expect = 3e-08, Method: Composition-based stats.
Identities = 20/107 (18%), Positives = 46/107 (42%), Gaps = 15/107 (14%)
Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491
+ +G+ ++LA + + + ++ + W+G++ L + D +A
Sbjct: 23 GGKLDGFEIDLANALCEKMKAKCQI-------------VAQNWDGIMPSLTGKKYDAIMA 69
Query: 492 PLTITLVREEVIDFSKPFMS--LGISIMIKKPQKSKPGVFSFLDPLA 536
+++T R+EVI FS P+ + G ++M PG+ +
Sbjct: 70 AMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGLGETYSLDS 116
Score = 32.8 bits (73), Expect = 0.76, Method: Composition-based stats.
Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKG-YGI---ATPK 752
++ EE + + + A L +T+ ++ K+ G L S G +G+ K
Sbjct: 162 YKSVEEHNLDLTSGRLD-AVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAVGLRK 220
Query: 753 -GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
+AL+ + A+ SE G + L KW+
Sbjct: 221 EDTALKADFDAAIKAASEDGTIKTLSLKWFK 251
>1HSL-A nrPDB
Length = 238
Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 21/155 (13%), Positives = 48/155 (30%), Gaps = 28/155 (18%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+ G+ ++LA E+ K + +
Sbjct: 15 APFESKNAQGE-------LVGFDIDLAKELCKRINTQCTF-------------VENPLDA 54
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
++ L + D ++ L+IT R++ I F+ + +++ K S + P
Sbjct: 55 LIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKN--------SDIQPTV 106
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFE 571
+ V G + F ++P ++
Sbjct: 107 ASLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQ 141
>3I6V-A nrPDB
Length = 232
Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats.
Identities = 22/93 (23%), Positives = 38/93 (40%), Gaps = 20/93 (21%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
PY + +G+ EL E+ K G + W+ +
Sbjct: 17 PYNFINDAGEV-------DGFERELGDELCKRAGLTCE-------------WVKNDWDSI 56
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510
+ LV G D +A ++IT R+EVIDF++ ++
Sbjct: 57 IPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89
Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats.
Identities = 29/160 (18%), Positives = 58/160 (36%), Gaps = 6/160 (3%)
Query: 625 IIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKM 684
++ +Y +A + I+ ++ T +Y G+ ++ A +
Sbjct: 60 LVSGNYDTIIAGMSITDERDEVIDFTQNYIPPTASSYVATSDGADLSGIVAAQTATIQAG 119
Query: 685 WTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSK 744
+ +S V T EE + VR + + + I + M VG ++
Sbjct: 120 Y-IAESGATLVEFATPEETIAAVRNGEADAVFA-DRDYLVPIVAESGGELMFVGDDVPLG 177
Query: 745 GYGIAT---PKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781
G G+ LRG + A+ + E G L+ + KW+
Sbjct: 178 G-GVGMGLRESDGELRGKFDAAITSMKEDGTLNTMIKKWF 216
>1IIT-A nrPDB
Length = 232
Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats.
Identities = 24/136 (17%), Positives = 54/136 (39%), Gaps = 21/136 (15%)
Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468
V + P+V + N + G +++ +A+ ++ Y ++
Sbjct: 6 LKVGVVGNPPFVFYGE-----GKNAAFTGISLDVWRAVAESQKWNSE--------YVRQN 52
Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEV--IDFSKPFMSLGISIMIKKPQKSKP 526
+ + + G D+ + P+++T R + I F++P+ S GI ++I P + P
Sbjct: 53 SISAG----ITAVAEGELDILIGPISVTPERAAIEGITFTQPYFSSGIGLLI--PGTATP 106
Query: 527 GVFSFLDPLAYEIWMC 542
S D E+ +
Sbjct: 107 LFRSVGDLKNKEVAVV 122
Score = 33.2 bits (74), Expect = 0.51, Method: Composition-based stats.
Identities = 15/92 (16%), Positives = 33/92 (35%), Gaps = 1/92 (1%)
Query: 691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIA 749
+ V I + + K A + + Y ++ P + + + YG
Sbjct: 134 YQADVRETNNLTAAITLLQKKQVEAVMFDRPALIYYTRQNPNLNLEVTEIRVSLEPYGFV 193
Query: 750 TPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781
+ S L+ +N+ +L L V+ + +W
Sbjct: 194 LKENSPLQKTINVEMLNLLYSRVIAEFTERWL 225
>1ISS-A nrPDB
Length = 490
Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats.
Identities = 52/354 (14%), Positives = 112/354 (31%), Gaps = 58/354 (16%)
Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPS-----FPVDTSNQFVLQLRPE---LQEAL 133
+ + G + + + I S T ++ L++ P A+
Sbjct: 124 IAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAM 183
Query: 134 ISIIDHYKWQTFVYIYDA-DRGLSVLQRVLDTAAEKNWQVTAVNIL--TTTEEGYRMLFQ 190
+ I+ Y W ++ + G S + + AA++ + + + E+ + L +
Sbjct: 184 LDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLR 243
Query: 191 DLEKK--KERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
L ++ K R+VV CE + +L + +L G ++ + G+ D D +
Sbjct: 244 KLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGE--FSLIGSDGWADRD-EVIEGYEV 300
Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDW------------------------- 283
G + + +TR W
Sbjct: 301 EANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKK 360
Query: 284 ---KRPKYTSALTYDG-VKVMAEAFQSL---RRQRIDISRRGNAGDCLANPAVPWGQGID 336
D + + A ++ + G+ G C A + G
Sbjct: 361 VCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPID---GRK 417
Query: 337 IQRALQQVRFEGLTG-NVQFNEKGRRTNYTLHVIEMKHDGIRK-----IGYWNE 384
+ L + F G++G V F+EKG ++ +++ + +G W+E
Sbjct: 418 LLDFLIKSSFVGVSGEEVWFDEKGDAPG-RYDIMNLQYTEANRYDYVHVGTWHE 470
>3DEL-B nrPDB
Length = 242
Score = 53.6 bits (127), Expect = 4e-07, Method: Composition-based stats.
Identities = 27/168 (16%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477
P+ + K G+ ++LA EI+ +G + + +++ +
Sbjct: 23 PFEFVDKRGEV-------VGFDIDLAREISNKLGKTLDVR-------------EFSFDAL 62
Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPL 535
+ L R D + ++IT R + I P+ I +++ K + P + +
Sbjct: 63 ILNLKQHRIDAVITGMSITPSRLKEI-LMIPYYGEEIKHLVLVFKGENKHPLPLTQYRSV 121
Query: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSN 583
A + AY+ + + S S E E G+ + +
Sbjct: 122 AVQT-GTYQEAYLQSLSEVHIRSFDSTLEVLME-VMHGKSPVAVLEPS 167
>5OWF-A nrPDB
Length = 259
Score = 52.5 bits (124), Expect = 8e-07, Method: Composition-based stats.
Identities = 16/102 (15%), Positives = 38/102 (37%), Gaps = 13/102 (12%)
Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489
+ + G+ ++L E+ K + ++ ++ L + D
Sbjct: 42 DAKGEFIGFDIDLGNEMCKRMQVK-------------CTWVASDFDALIPSLKAKKIDAI 88
Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 531
++ L+IT R++ I FS + ++ K +P + S
Sbjct: 89 ISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLESL 130
>1YK0-A nrPDB
Length = 480
Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats.
Identities = 49/374 (13%), Positives = 105/374 (28%), Gaps = 54/374 (14%)
Query: 31 FPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYE 90
+ A R T L P + + R V A G
Sbjct: 69 LTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKP 128
Query: 91 RRTVNMLTSFCGALHVCFITPSFPV---------------DTSNQFVLQLRPE---LQEA 132
+ + + A V + + + D+ + ++ P + E
Sbjct: 129 DLILGPVCEYAAA-PVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEM 187
Query: 133 LISIIDHYKWQTFVYIYDADR----GLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188
++++ H+ W +Y D+ L+ V + E+ + + T + +
Sbjct: 188 MLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDI 247
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
+++ + ER+V++ S+ + +I+ + Y + L + + G
Sbjct: 248 VRNI-QASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGD 306
Query: 249 N--------VTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALT---YDGV 297
+ Q V T+ +++ + Y + +D +
Sbjct: 307 KHDFEAKQAYSSLQTVTLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAI 365
Query: 298 KVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE 357
+ A + R G N FEG+ G V +
Sbjct: 366 LLYVLALHEVLRAGYSKKDGGKIIQQTWNR-----------------TFEGIAGQVSIDA 408
Query: 358 KGRRTNYTLHVIEM 371
G R VI M
Sbjct: 409 NGDR-YGDFSVIAM 421
>3A3K-A nrPDB
Length = 435
Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats.
Identities = 50/405 (12%), Positives = 127/405 (31%), Gaps = 63/405 (15%)
Query: 41 AFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAI-----------FGFY 89
A AL+++ P LLP + + S E CS + + A+ G
Sbjct: 26 AVELALARVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPG 85
Query: 90 ERRTVNMLTSFCGALHVCFIT---PSFPVDTSNQFVLQLRPELQEALI-----SIIDHYK 141
+ + F V +T P+ + +++ L R + ++
Sbjct: 86 CVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLG 145
Query: 142 WQTFVYIYDADRGLSV-----LQRVLDTAAEKNWQVT-AVNILTTTEEGYRMLFQDLEKK 195
W+ + ADR + L + +T + + ++
Sbjct: 146 WEHQALVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLLRAVRR 205
Query: 196 KERLVVVDCESERLNAILGQIVKLEKNGIGYHY---------------ILANLGFMDIDL 240
K R++ + + ++ + G Y + ++ + D
Sbjct: 206 KGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKSAQGLVPQKPWERGDG 265
Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTR----VDWKRPKYTSALTYDG 296
+ + +++ Y + ++ + + V+ A +DG
Sbjct: 266 QD-RSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTVEDGLKNIIPASFHDG 324
Query: 297 VKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFN 356
+ + +A Q ++ G +I + + F+G+TG ++ +
Sbjct: 325 LLLYVQAVTETLAQGGTVTD-----------------GENITQRMWNRSFQGVTGYLKID 367
Query: 357 EKGRR-TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGD 400
G R T+++L ++ + R + +N + + A ++ +
Sbjct: 368 RNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQELMAVSEHKLYWP 412
>4Q0C-A nrPDB
Length = 584
Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats.
Identities = 19/117 (16%), Positives = 45/117 (38%), Gaps = 21/117 (17%)
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
P+ + + + +++ G + + G + + V +
Sbjct: 351 APFTLFRTD-------EQFGGISAAVLQLLQLRTGLDFEIIGVDTVEE------------ 391
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 533
++ +L G AD+A L + RE + FS+P++ G+ +++ + P LD
Sbjct: 392 LIAKLRSGEADMA-GALFVNSARESFLSFSRPYVRNGM-VIVTRQDPDAPVDADHLD 446
>2Q88-A nrPDB
Length = 257
Score = 40.9 bits (94), Expect = 0.003, Method: Composition-based stats.
Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
E P+ + + G ++A EI K +G + + S +YGA
Sbjct: 22 EPPF-------TAVGADGKVSGAAPDVAREIFKRLGVAD--VVASISEYGA--------- 63
Query: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL--D 533
M+ L GR D A L + R + +S+P + + +KK + + +
Sbjct: 64 -MIPGLQAGRHDAITAGLFMKPERCAAVAYSQPILCDAEAFALKKGNPLGLKSYKDIADN 122
Query: 534 PLAY 537
P A
Sbjct: 123 PDAK 126
>4PX2-A nrPDB
Length = 638
Score = 33.2 bits (74), Expect = 0.46, Method: Composition-based stats.
Identities = 16/99 (16%), Positives = 29/99 (29%), Gaps = 1/99 (1%)
Query: 151 ADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLN 210
G Q V++T W+++ E L QDL+K +V
Sbjct: 12 DMPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAE 71
Query: 211 AILGQIVKLEKNGIGYH-YILANLGFMDIDLNKFKESGA 248
+ L Y IL + + + + +
Sbjct: 72 IFQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPD 110
>4DX0-A nrPDB
Length = 243
Score = 32.8 bits (73), Expect = 0.72, Method: Composition-based stats.
Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 2/84 (2%)
Query: 630 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMK 689
Y A LA ER +E E +AK ++ T+E + ++ I W +
Sbjct: 16 YMAKLAE--QAERYEEMVEFMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIIS 73
Query: 690 SAEPSVFVRTTEEGMIRVRKSKGK 713
S E R E+ + +++ +GK
Sbjct: 74 SIEQKEESRGNEDHVSSIKEYRGK 97
>4V8M-A5 nrPDB
Length = 220
Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats.
Identities = 9/43 (20%), Positives = 22/43 (51%)
Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRN 862
+ + F + + + ++R + ++ + NE +RT TL +N
Sbjct: 57 GLRLDTGNFAWGTEASAQRARILDVVYNATSNELVRTKTLVKN 99
>5XXU-I nrPDB
Length = 205
Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats.
Identities = 12/44 (27%), Positives = 25/44 (56%)
Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNS 863
A+ + + + S+ +K+ + ++ S NE +RT+TL +NS
Sbjct: 57 ALRLDTGNYSWSSQKIAKKTRLLGVVYNASNNELVRTNTLVKNS 100
>5OPT-Z nrPDB
Length = 221
Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats.
Identities = 9/43 (20%), Positives = 22/43 (51%)
Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRN 862
+ + F + + + ++R + ++ + NE +RT TL +N
Sbjct: 57 GLRLDTGNFAWSTEAIAQRARILDVVYNATSNELVRTKTLVKN 99
>3AXY-C nrPDB
Length = 240
Score = 30.9 bits (68), Expect = 2.6, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 2/84 (2%)
Query: 630 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMK 689
Y A LA ER +E E +AK ++ T+E + ++ I W +
Sbjct: 13 YMAKLAE--QAERYEEMVEYMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIVS 70
Query: 690 SAEPSVFVRTTEEGMIRVRKSKGK 713
S E R EE + +++ +GK
Sbjct: 71 SIEQKEEGRGNEEHVTLIKEYRGK 94
>3IP9-A nrPDB
Length = 356
Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats.
Identities = 47/322 (14%), Positives = 93/322 (28%), Gaps = 44/322 (13%)
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF--PVDTS-- 118
++SD + + GV + G + + + ITP+ PV T
Sbjct: 51 DVSDPKQGISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERG 110
Query: 119 --NQFVLQLRPELQEALIS--IIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTA 174
N F R + Q + + DH+K I+D L AA VT
Sbjct: 111 LWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAA-NAAGVTE 169
Query: 175 VNI--LTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232
V + ++ + L +++ ++ I+ Q
Sbjct: 170 VMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAK-------- 221
Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292
L D ++ A++ G + +T + + + + P+ +
Sbjct: 222 LVSGDGIVSN---ELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLY 278
Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352
+Y M + + + + AL++ F G
Sbjct: 279 SY---AAMQAIAGAAKAAGSVEPEK-------------------VAEALKKGSFPTALGE 316
Query: 353 VQFNEKGRRTNYTLHVIEMKHD 374
+ F+EKG + E K
Sbjct: 317 ISFDEKGDPKLPGYVMYEWKKG 338
>4V6W-AI nrPDB
Length = 208
Score = 30.1 bits (66), Expect = 4.9, Method: Composition-based stats.
Identities = 12/44 (27%), Positives = 23/44 (52%)
Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNS 863
A+ + F + S +++ + ++ S NE +RT TL +NS
Sbjct: 57 ALRLETGNFAWASEGVARKTRIADVVYNASNNELVRTKTLVKNS 100
>2F6U-A nrPDB
Length = 234
Score = 29.7 bits (65), Expect = 5.5, Method: Composition-based stats.
Identities = 16/135 (11%), Positives = 41/135 (30%), Gaps = 10/135 (7%)
Query: 138 DHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQ-VTAVNILTTTEEGYRMLFQDLEKKK 196
H +W+ + +I D + ++ A+ V T E R L + + +
Sbjct: 2 SHMRWRKWRHITKLDPDRTNTDEIIKAVADSGTDAVMISGTQNVTYEKARTLIEKVSQYG 61
Query: 197 ERLVVVDCESERLNA---------ILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESG 247
+VV + + +L G ++ + + +
Sbjct: 62 LPIVVEPSDPSNVVYDVDYLFVPTVLNSADGDWITGKHAQWVRMHYENLQKFTEIIESEF 121
Query: 248 ANVTGFQLVNYTDTI 262
+ G+ ++N +
Sbjct: 122 IQIEGYIVLNPDSAV 136
>5A5X-A nrPDB
Length = 453
Score = 29.0 bits (63), Expect = 8.6, Method: Composition-based stats.
Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 14/105 (13%)
Query: 429 FEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGEL-VYGRAD 487
F+ + G+ ELA A+ +G ++E + + + +L G
Sbjct: 20 FQDRNGETGFEYELAKRFAERLGVELKIETADNL------------DDLYAQLSREGGPA 67
Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532
+A A LT + + +S ++ + I+ + Q +P L
Sbjct: 68 LAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQ-QRPTRPEDL 111
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.310 0.125 0.321
Lambda K H
0.267 0.0384 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,151,175
Number of Sequences: 36641
Number of extensions: 1138745
Number of successful extensions: 3891
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3263
Number of HSP's gapped (non-prelim): 261
length of query: 907
length of database: 10,336,785
effective HSP length: 106
effective length of query: 801
effective length of database: 6,452,839
effective search space: 5168724039
effective search space used: 5168724039
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 63 (29.0 bits)