BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23818 (907 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6QKC-A nrPDB 1852 0.0 4U1Y-A nrPDB 1238 0.0 5IDF-B nrPDB 1228 0.0 5KUF-A nrPDB 645 0.0 5KUH-A nrPDB 312 4e-85 5O9A-A nrPDB 273 2e-73 3FAT-A nrPDB 273 3e-73 3DP4-A nrPDB 270 3e-72 5UOW-A nrPDB 247 2e-65 5FXI-A nrPDB 239 4e-63 5UN1-G nrPDB 222 4e-58 6IRA-D nrPDB 196 5e-50 5UN1-B nrPDB 194 1e-49 5IPR-B nrPDB 184 1e-46 4PE5-B nrPDB 181 1e-45 5UP2-B nrPDB 174 2e-43 1YAE-A nrPDB 171 1e-42 5DT6-A nrPDB 169 5e-42 5L2E-A nrPDB 169 5e-42 5EHM-A nrPDB 162 4e-40 2XXT-A nrPDB 154 2e-37 5IKB-A nrPDB 153 3e-37 4MF3-A nrPDB 153 3e-37 4IGR-A nrPDB 149 7e-36 4WXJ-A nrPDB 102 8e-22 5CC2-A nrPDB 89 9e-18 5I2K-B nrPDB 88 1e-17 3OEK-A nrPDB 85 2e-16 5H8N-A nrPDB 82 8e-16 2RCB-A nrPDB 77 2e-14 2RC9-A nrPDB 75 2e-13 4YKP-A nrPDB 68 2e-11 5TUJ-C nrPDB 56 7e-08 4ZDM-A nrPDB 55 2e-07 4F3P-A nrPDB 52 2e-06 4PSH-A nrPDB 49 1e-05 4ZV2-A nrPDB 47 3e-05 4IO3-A nrPDB 46 6e-05 4F3S-A nrPDB 46 8e-05 3K4U-A nrPDB 45 1e-04 1GGG-A nrPDB 44 3e-04 5JOS-A nrPDB 43 5e-04 4H5F-A nrPDB 42 8e-04 2PYY-A nrPDB 40 0.004 5OTA-A nrPDB 40 0.007 4MS4-A nrPDB 38 0.016 4YMX-A nrPDB 37 0.030 4ZEF-A nrPDB 37 0.031 4I62-A nrPDB 37 0.036 6FXG-A nrPDB 35 0.13 4KPT-A nrPDB 35 0.15 5LOM-A nrPDB 35 0.16 2IEE-A nrPDB 35 0.17 3I6V-A nrPDB 34 0.26 2Q2A-A nrPDB 34 0.34 3EIQ-A nrPDB 33 0.52 4OEN-A nrPDB 33 0.70 3TQL-A nrPDB 33 0.75 5ORE-A nrPDB 32 0.96 2HYI-C nrPDB 32 1.2 5EYF-A nrPDB 32 1.4 5HPQ-A nrPDB 31 2.5 5VXG-A nrPDB 31 2.7 3F41-A nrPDB 30 3.2 6J0J-A nrPDB 30 6.7 6F6P-A nrPDB 29 8.0 5GZU-A nrPDB 29 9.1 >6QKC-A nrPDB Length = 915 Score = 1852 bits (4796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 905/915 (98%), Positives = 906/915 (99%), Gaps = 8/915 (0%) Query: 1 MPYIFAFFCTGFLGAVVGA--------NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 52 MPYIFAFFCTGFLGAVVGA NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP Sbjct: 1 MPYIFAFFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 60 Query: 53 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS Sbjct: 61 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 120 Query: 113 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 172 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV Sbjct: 121 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 180 Query: 173 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN Sbjct: 181 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 240 Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSD+RDHTRVDWKRPKYTSAL Sbjct: 241 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSAL 300 Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN Sbjct: 301 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 360 Query: 353 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 412 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT Sbjct: 361 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 420 Query: 413 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 472 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK Sbjct: 421 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 480 Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL Sbjct: 481 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540 Query: 533 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 592 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 600 Query: 593 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660 Query: 653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 712 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG Sbjct: 661 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 720 Query: 713 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV Sbjct: 721 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 780 Query: 773 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS Sbjct: 781 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 840 Query: 833 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIP 892 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGG GSGENGRVVSQDFPKSMQSIP Sbjct: 841 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIP 900 Query: 893 CMSHSSGMPLGATGL 907 CMSHSSGMPLGATGL Sbjct: 901 CMSHSSGMPLGATGL 915 >4U1Y-A nrPDB Length = 819 Score = 1238 bits (3204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 589/830 (70%), Positives = 703/830 (84%), Gaps = 16/830 (1%) Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQIDIVNISDSFEMTYRFCSQFSKG 81 N+IQIGGLFP QE++AFR + Q T +L P ID + +++SF +T FCSQFS+G Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRG 60 Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYK 141 VYAIFGFY++++VN +TSFCG LHV FITPSFP D ++ FV+Q+RP+L+ AL+S+I++Y+ Sbjct: 61 VYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQ 120 Query: 142 WQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT----EEGYRMLFQDLEKKKE 197 W F Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+ +E YR LFQDLE KKE Sbjct: 121 WDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKE 180 Query: 198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257 R V++DCE +++N I+ Q++ + K+ GYHYI+ANLGF D DL K + GA V+GFQ+V+ Sbjct: 181 RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVD 240 Query: 258 YTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRR 317 Y D++ ++ +++W T + +++ KYTSALTYD V+VM EAF++LR+QRI+ISRR Sbjct: 241 YDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRR 300 Query: 318 GNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIR 377 GNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F++ G+R NYT++++E+K +G R Sbjct: 301 GNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPR 360 Query: 378 KIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEG 437 KIGYW+E DK V T+ D S ++ +T +VTTILE PYVM+KKN EGN+RYEG Sbjct: 361 KIGYWSEVDKMVVTLTE----DDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEG 416 Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITL 497 YCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WNGMVGELVYG+AD+A+APLTITL Sbjct: 417 YCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITL 476 Query: 498 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 557 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSVVLFLV Sbjct: 477 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLV 536 Query: 558 SRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGG 617 SRFSPYEWH+EEFE+G + T NEFGIFNS WF+L F QQG DISPRSLS RIV G Sbjct: 537 SRFSPYEWHTEEFEDGEEST-----NEFGIFNSFWFALKLFFQQGADISPRSLSARIVAG 591 Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSK 677 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTL++GSTKEFFRRSK Sbjct: 592 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK 651 Query: 678 IAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 737 IAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV Sbjct: 652 IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 711 Query: 738 GGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDK 797 GGNLDSKGYGIATPKGS+L PVNLAVLKLSEQGVLDKLK+KWWYDKGECG+KDSGSK+K Sbjct: 712 GGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEK 771 Query: 798 TSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847 TSALSLSNVAGVFYIL+GGLGLAMLVALIEF YKSR+E+KRMKG L+P+ Sbjct: 772 TSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMKG--LVPR 819 >5IDF-B nrPDB Length = 874 Score = 1228 bits (3176), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/830 (71%), Positives = 692/830 (83%), Gaps = 11/830 (1%) Query: 21 FPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEPP-KLLPQIDIVNISDSFEMTYR 73 FPN I IGGLF QEH+AFRFA+ TE P L +D ++ S+SF +T Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69 Query: 74 FCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEAL 133 FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D QFV+Q+RP L+ A+ Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129 Query: 134 ISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE-EGYRMLFQDL 192 +S++ +YKW+ FVY+YD +RG SVLQ +++ A + NWQVTA ++ + + +R + +++ Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189 Query: 193 EKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTG 252 ++++E+ ++DCE ER+N IL Q+V L K+ GYHY+LANLGF DI L + GAN+TG Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249 Query: 253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRI 312 FQ+VN + + + +Q+W D + KYTSALT+D + V+AEAF+ LRRQR+ Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309 Query: 313 DISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK 372 D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+ GRRTNYT+ V EMK Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369 Query: 373 HDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGN 432 G RK GYWNE ++FVP +D Q D+SS +NRT +VTTILE PYVM KKN Q EGN Sbjct: 370 VSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 428 Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492 +RYEGYCV+LA EIAKHVG Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAP Sbjct: 429 ERYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 488 Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV Sbjct: 489 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 548 Query: 553 VLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSL 610 VLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIFNSLWFSLGAFMQQGCDISPRSL Sbjct: 549 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 608 Query: 611 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTK 670 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL++GSTK Sbjct: 609 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 668 Query: 671 EFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK 730 EFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+LLESTMNEYIEQRK Sbjct: 669 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 728 Query: 731 PCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790 PCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAVLKLSEQG+LDKLK+KWWYDKGECG+K Sbjct: 729 PCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 788 Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840 DSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ESKRMK Sbjct: 789 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 838 >5KUF-A nrPDB Length = 877 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/848 (41%), Positives = 516/848 (60%), Gaps = 54/848 (6%) Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74 ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + + Sbjct: 5 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 64 Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128 C Q S GV AIFG + N + S C AL V I + D + F + L P+ Sbjct: 65 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 124 Query: 129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188 L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + L Sbjct: 125 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 183 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248 +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG Sbjct: 184 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 243 Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304 N+TGF+++N +T + I+++W + + D +AL YD V V++ A Sbjct: 244 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 303 Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363 Q + + ++ C N PW G +++ +EGLTG + FN+ G RT+ Sbjct: 304 QQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 355 Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416 + L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE Sbjct: 356 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 409 Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 +PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG Sbjct: 410 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNG 469 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536 MV EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ Sbjct: 470 MVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLS 529 Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLG 596 +IWM ++ AY+GVSVVLF+++RFSPYEW++ + + N F + NS WF +G Sbjct: 530 PDIWMYVLLAYLGVSVVLFVIARFSPYEWYN---PHPCNPDSDVVENNFTLLNSFWFGVG 586 Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656 A MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQ Sbjct: 587 ALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQ 646 Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716 T+I YG +E GST FF++SKI+ ++KMW +M S SV V+++EEG+ RV S YA Sbjct: 647 TKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYAL 704 Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776 L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L + Sbjct: 705 LMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMM 763 Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836 K KWW G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ + Sbjct: 764 KEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA 819 Query: 837 KRMK-GFC 843 + K FC Sbjct: 820 QLEKRSFC 827 >5KUH-A nrPDB Length = 757 Score = 312 bits (800), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 203/595 (34%), Positives = 314/595 (52%), Gaps = 57/595 (9%) Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74 ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + + Sbjct: 5 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 64 Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128 C Q S GV AIFG + N + S C AL V I + D + F + L P+ Sbjct: 65 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 124 Query: 129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188 L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + L Sbjct: 125 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 183 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248 +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG Sbjct: 184 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 243 Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304 N+TGF+++N +T + I+++W + + D +AL YD V V++ A Sbjct: 244 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 303 Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363 Q + + ++ C N PW G +++ +EGLTG + FN+ G RT+ Sbjct: 304 QQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 355 Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416 + L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE Sbjct: 356 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 409 Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 +PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG Sbjct: 410 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNG 469 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQKSKPGVFSFLDP 534 MV EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K P S D Sbjct: 470 MVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSA-------DD 522 Query: 535 LAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTTSDQSNEFGI 587 LA + + G ++ F S+ S Y+ W F R Q+ +S+E GI Sbjct: 523 LAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMW---AFMSSRRQSVLVKSSEEGI 574 Score = 179 bits (453), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 92/203 (45%), Positives = 135/203 (66%), Gaps = 8/203 (3%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PI+SA+DLAKQT+I YG +E GST FF++SKI+ ++KMW +M S SV V+++E Sbjct: 512 RKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSE 571 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RV S YA L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 572 EGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 628 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAM 821 +A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL L++ Sbjct: 629 IAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSV 684 Query: 822 LVALIEFCYKSRSESK-RMKGFC 843 VA+ EF YKS+ ++ + FC Sbjct: 685 FVAVGEFLYKSKKNAQLEKRSFC 707 >5O9A-A nrPDB Length = 264 Score = 273 bits (699), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 130/145 (89%), Positives = 140/145 (96%) Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704 +PIESAEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ Sbjct: 119 TPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 178 Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764 RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+L VNLAV Sbjct: 179 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAV 238 Query: 765 LKLSEQGVLDKLKSKWWYDKGECGS 789 LKLSEQG+LDKLK+KWWYDKGECGS Sbjct: 239 LKLSEQGLLDKLKNKWWYDKGECGS 263 Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 92/115 (80%), Positives = 102/115 (88%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 N+T +VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYG Sbjct: 3 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYG 62 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 ARD DTK WNGMVGELVYG+AD+A+APLTIT VREEVIDFSKPFMSLGISIMIKK Sbjct: 63 ARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKK 117 >3FAT-A nrPDB Length = 260 Score = 273 bits (697), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 128/144 (88%), Positives = 139/144 (96%) Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704 +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ Sbjct: 117 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 176 Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764 RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+LR PVNLAV Sbjct: 177 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAV 236 Query: 765 LKLSEQGVLDKLKSKWWYDKGECG 788 LKLSE GVLDKLK+KWWYDKGECG Sbjct: 237 LKLSEAGVLDKLKNKWWYDKGECG 260 Score = 197 bits (500), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 90/114 (78%), Positives = 102/114 (89%) Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 RT +VTTI+E PYVM KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGA Sbjct: 2 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 61 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 RD DTK WNGMVGELVYG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKK Sbjct: 62 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 115 >3DP4-A nrPDB Length = 278 Score = 270 bits (689), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 126/144 (87%), Positives = 139/144 (96%) Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704 +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ Sbjct: 135 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 194 Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764 RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAV Sbjct: 195 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAV 254 Query: 765 LKLSEQGVLDKLKSKWWYDKGECG 788 LKLSEQG+LDKLK+KWWYDKGECG Sbjct: 255 LKLSEQGILDKLKNKWWYDKGECG 278 Score = 207 bits (526), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 100/133 (75%), Positives = 108/133 (81%) Query: 388 FVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIA 447 VP + D+S NRT +VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIA Sbjct: 1 LVPRGSAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIA 60 Query: 448 KHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSK 507 KHV Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSK Sbjct: 61 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 120 Query: 508 PFMSLGISIMIKK 520 PFMSLGISIMIKK Sbjct: 121 PFMSLGISIMIKK 133 >5UOW-A nrPDB Length = 814 Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 220/879 (25%), Positives = 398/879 (45%), Gaps = 135/879 (15%) Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 77 P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C Sbjct: 2 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 59 Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125 S VYAI + + LT S+ + V +T + + F+ + Sbjct: 60 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 119 Query: 126 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 183 P +AL+ ++ + W + I D Q+ L+T E+ + + + + E Sbjct: 120 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 177 Query: 184 GYRMLFQDLEKKKE---RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 240 G + L L + KE R++++ + A+ L+ G GY +++ G +I Sbjct: 178 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 234 Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVM 300 + + + + G QL+N K SA D V V+ Sbjct: 235 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 266 Query: 301 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 358 A+A L ++I RG C+ N + W G +R L ++ +G+TG ++FNE Sbjct: 267 AQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNED 321 Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 411 G R ++ +++ + ++G ++ D K + P + G S + + + Sbjct: 322 GDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 378 Query: 412 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 442 TI ++P+V ++ + + Y G+CV+L Sbjct: 379 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDL 438 Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLV 498 ++A+ + ++Y + +V+DGK+G ++ + AWNGM+GEL+ G+AD+ VAPLTI Sbjct: 439 LIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNE 498 Query: 499 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 558 R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ Sbjct: 499 RAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 557 Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIV 615 RFSP+ GR + S + E + +++WFS + G + +PRS S RI+ Sbjct: 558 RFSPF---------GRFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARIL 608 Query: 616 GGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEF 672 G VW F +II++SYTANLAAFL + R I D + + Y T++ S + Sbjct: 609 GMVWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIY 668 Query: 673 FRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPC 732 FRR M+ +M+ + E + VR +K +A++ +S + E+ E + C Sbjct: 669 FRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQDC 720 Query: 733 DTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDS 792 D + G G+GI K S + V+L +LK E G +++L K W EC S+ + Sbjct: 721 DLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRSN 779 Query: 793 GSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYK 831 + L+ N+AGVFY++ GG+ + + IE YK Sbjct: 780 AP----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >5FXI-A nrPDB Length = 846 Score = 239 bits (610), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 184/697 (26%), Positives = 329/697 (47%), Gaps = 108/697 (15%) Query: 188 LFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESG 247 L + + + R++++ + + L+ G GY +++ G +I N + + Sbjct: 206 LLMEARELEARVIILSASEDDAATVYRAAAMLDMTGSGYVWLV---GEREISGNALRYAP 262 Query: 248 ANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL 307 + G QL+N K SA D V V+A+A L Sbjct: 263 DGIIGLQLIN----------------------------GKNESAHISDAVGVVAQAVHEL 294 Query: 308 -RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEKGRRTNYT 365 ++ I RG C+ N + W G +R L ++ +G+TG V+FNE G R Sbjct: 295 LEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQ 349 Query: 366 LHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIVTTILEDP 418 ++ +++ + ++G +N D K + P + G S + + + TI ++P Sbjct: 350 YSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLK---IVTIHQEP 406 Query: 419 YVMLKKNA-------------------------NQFEGNDRYE------GYCVELAAEIA 447 +V +K + G+ R+ G+C++L ++A Sbjct: 407 FVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLA 466 Query: 448 KHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVI 503 + + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI R + I Sbjct: 467 RTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYI 526 Query: 504 DFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPY 563 +FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ RFSP Sbjct: 527 EFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSP- 584 Query: 564 EWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGGVWWFF 622 F + + S+ ++ + +++WFS G + G + +PRS S RI+G VW F Sbjct: 585 ------FGRFKVNSQSESTDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGF 638 Query: 623 TLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIA 679 +II++SYTANLAAFL ++R I D + + Y T++ S +FRR Sbjct: 639 AMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--V 696 Query: 680 VFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG 739 M+ +M+ + E + VR +K +A++ +S + E+ E + CD + G Sbjct: 697 ELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGE 750 Query: 740 NLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTS 799 G+GI K S + V+L++LK E G ++ L K W EC S+ + + Sbjct: 751 LFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDL-DKTWVRYQECDSRSNAP----A 805 Query: 800 ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836 L+ N+AGVF ++ GG+ + + IE YK ++ Sbjct: 806 TLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDA 842 >5UN1-G nrPDB Length = 451 Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 139/419 (33%), Positives = 231/419 (55%), Gaps = 37/419 (8%) Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAP 492 G+CV+L ++A+ + ++Y + +V+DGK+G ++ + AWNGM+GEL+ G+AD+ VAP Sbjct: 62 GFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAP 121 Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552 LTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V Sbjct: 122 LTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 180 Query: 553 VLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLS 611 +L+L+ RFSP+ GR + + + +++WFS + G + +PRS S Sbjct: 181 MLYLLDRFSPF---------GRFE------DALTLSSAMWFSWRVLLNSGLGEGAPRSFS 225 Query: 612 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGS 668 RI+G VW F +II++SYTANLAAFL + R I D + + Y T++ S Sbjct: 226 ARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSS 285 Query: 669 TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQ 728 +FRR M+ +M+ + E + VR +K +A++ +S + E+ E Sbjct: 286 VDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EA 337 Query: 729 RKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 + CD + G G+GI K S + V+L +LK E G +++L K W EC Sbjct: 338 SQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECD 396 Query: 789 SKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847 S+ + + L+ N+AGVF ++ GG+ + + IE YKSR+E+KRMKG ++ Q Sbjct: 397 SRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLFQ 451 >6IRA-D nrPDB Length = 853 Score = 196 bits (497), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 193/774 (24%), Positives = 344/774 (44%), Gaps = 106/774 (13%) Query: 114 PVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN---W 170 P T QF ++ + ++ I+ Y W F + G + T + + W Sbjct: 140 PTSTFFQFGASIQQQ-ATVMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGW 198 Query: 171 QVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYIL 230 + V L T+ E + Q L+K ++++ C + IL + L G + +I+ Sbjct: 199 DMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIV 257 Query: 231 ANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKY 288 +L G ++ +F +G V+Y D W S Sbjct: 258 PSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------------- 287 Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISR-RGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347 A DG+ ++ A S+ + I + + + P VP + + V ++ Sbjct: 288 LEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHT---LHPFMVNVTWD 344 Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAAT--DAQAGGDNSSV 404 G ++ F E+G + + L VI + D K+G W + A ++ D Sbjct: 345 G--KDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPD 402 Query: 405 QNRTYIVTTILEDPYVML---------------------KKNANQFEGNDRYE---GYCV 440 N IVT + E P+V++ K N + EG + + G+C+ Sbjct: 403 DNHLSIVT-LEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCI 461 Query: 441 ELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVRE 500 ++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI R Sbjct: 462 DILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTINEERS 519 Query: 501 EVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVS 558 EV+DFS PF+ GIS+M+ + + P +FL+P + +W M V I ++ +F+ Sbjct: 520 EVVDFSVPFVETGISVMVSRSNGTVSPS--AFLEPFSASVWVMMFVMLLIVSAIAVFVFE 577 Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGG 617 FSP ++ +G+ + F I ++W G + +P+ + +I+ Sbjct: 578 YFSPVG-YNRNLAKGK----APHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVS 632 Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAY------GTLEAGSTKE 671 VW FF +I ++SYTANLAAF+ R V + D Q Y GT+ GST+ Sbjct: 633 VWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTER 692 Query: 672 FFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-K 730 R + + YM + E+ ++ ++ K A++ ++ + Y R + Sbjct: 693 NIRNN--------YPYMHQYMTKFNQKGVEDALVSLKTGKLD-AFIYDAAVLNYKAGRDE 743 Query: 731 PCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 C + +G + GYGIA KGS + ++LA+L+ G +++L++ W G C Sbjct: 744 GCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGIC- 800 Query: 789 SKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE-FCYKSRSESKRMKG 841 + ++ +S L + N+AGVFY+L + L+++ + E YKSR+E+KRMKG Sbjct: 801 -HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMKG 853 >5UN1-B nrPDB Length = 448 Score = 194 bits (493), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 130/425 (30%), Positives = 226/425 (53%), Gaps = 45/425 (10%) Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 +G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA +AV LTI Sbjct: 56 KGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTI 113 Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVV 553 R EV+DFS PF+ GIS+M+ + + P +FL+P + ++W M V I +V Sbjct: 114 NEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLLIVSAVA 171 Query: 554 LFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 612 +F+ FSP ++ F G+ ++W G + +P+ + Sbjct: 172 VFVFEYFSPVGYNGPSFTIGK---------------AIWLLWGLVFNNSLPVQNPKGTTS 216 Query: 613 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEA 666 +I+ VW FF +I ++SYTANLAAF+ R V + D Q +GT+ Sbjct: 217 KIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPN 276 Query: 667 GSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYI 726 GST+ R + + +M +YM R+ ++ ++ ++ K A++ ++ + Y+ Sbjct: 277 GSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDAAVLNYM 327 Query: 727 EQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783 R + C + +G + GYGIA K S + V+LA+L+L G +++L++ W Sbjct: 328 AGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL-- 385 Query: 784 KGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE-FCYKSRSESKRMKGF 842 G C + ++ +S L + N+AGVFY+L + L+++ ++E YKSR+E+KRMKG Sbjct: 386 TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGL 443 Query: 843 CLIPQ 847 ++ Q Sbjct: 444 EVLFQ 448 >5IPR-B nrPDB Length = 825 Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 187/833 (22%), Positives = 366/833 (43%), Gaps = 127/833 (15%) Query: 57 PQIDIVNI--SDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP 114 P++++V + SD + R C S F + + + V +TP Sbjct: 61 PRVELVTMQESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILG 120 Query: 115 VDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRV 161 + + ++ Q P +++ +++I++ Y W F + G + Sbjct: 121 IHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENK 180 Query: 162 LDTAAEKN---WQVTAVNILTTTEEGYRMLFQD-LEKKKERLVVVDCESERLNAILGQIV 217 + + E + W++ V L + + Q+ L+K + ++++ C E I Sbjct: 181 VRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAH 240 Query: 218 KLEKNGIGYHYILANLGFMDIDL--NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDA 275 + G G+ +I+ +L D D ++F TG V+Y +W Sbjct: 241 SVGLTGYGFTWIVPSLVAGDTDTVPDEFP------TGLISVSY---------DEW----- 280 Query: 276 RDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGI 335 D+ P A DG+ ++ A ++ + I + ++ + + V + Sbjct: 281 ------DYDLP----ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YEAH 328 Query: 336 DIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAATD 394 ++R L V FEG ++ F+E G + + L +I + + ++G + + + D Sbjct: 329 MLKRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPVFD 386 Query: 395 AQAGGDNSSVQNRTYIVTTILEDPYVMLK--------------------KNANQFEGNDR 434 + ++ + + T+ E P+V+++ + N+ E Sbjct: 387 LYPNSEEHKDEHLS--IVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGN 444 Query: 435 Y-----EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 Y +G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA +A Sbjct: 445 YIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMA 502 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAY 547 V LTI R EV+DFS PF+ GIS+M+ + + P +FL+P + ++W M V Sbjct: 503 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLL 560 Query: 548 IGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-S 606 I +V +F+ FSP ++ F G+ ++W G + + Sbjct: 561 IVSAVAVFVFEYFSPVGYNGPSFTIGK---------------AIWLLWGLVFNNSLPVQN 605 Query: 607 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIA 660 P+ + +I+ VW FF +I ++SYTANLAAF+ R V + D Q Sbjct: 606 PKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFR 665 Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720 +GT+ GST+ R + + +M +YM R+ ++ ++ ++ K A++ ++ Sbjct: 666 FGTVPNGSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDA 716 Query: 721 TMNEYIEQRKP-CDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777 + Y+ R C + +G + GYGIA K S + V+LA+L+L G +++L+ Sbjct: 717 AVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELE 776 Query: 778 SKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830 + W G C + ++ +S L + N+AGVFY+L + L+++ ++E + Sbjct: 777 ALWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825 >4PE5-B nrPDB Length = 820 Score = 181 bits (459), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 191/771 (24%), Positives = 341/771 (44%), Gaps = 136/771 (17%) Query: 116 DTSNQFVLQLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN--- 169 D S+ F Q P +++ +++I++ Y W F + G + + E + Sbjct: 112 DESSMF-FQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVG 170 Query: 170 WQVTAVNILTTT-EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHY 228 W++ V +L + ++G + L+K + ++++ C E I + G GY + Sbjct: 171 WELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTW 230 Query: 229 ILANLGFMDIDL--NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRP 286 I+ +L D D ++F TG V+Y +W D+ P Sbjct: 231 IVPSLVAGDTDTVPSEFP------TGLISVSY---------DEW-----------DYGLP 264 Query: 287 KYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF 346 A DG+ ++ A + + I ++ C Q + R L V F Sbjct: 265 ----ARVRDGIAIITTAASDMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTF 318 Query: 347 EGLTGNVQFNEKGRRTNYTLHVIEM-KHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQ 405 EG ++ F+E G + + L +I + K ++G W + S+Q Sbjct: 319 EG--RDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKD-----------------KSLQ 359 Query: 406 NRTYI-----------VTTILEDPYVMLKK--------------------NANQFEGNDR 434 + Y+ + T+ E P+V+++ + N+ + Sbjct: 360 MKYYVWPRMTQDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPG 419 Query: 435 Y-----EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 Y +G+C+++ +I+K V ++Y L +V++GK+G + T WNGM+GE+V RA +A Sbjct: 420 YIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGT--WNGMIGEVVMKRAYMA 477 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAY 547 V LTI R EV+DFS PF+ GIS+M+ + + P +FL+P + +W M V Sbjct: 478 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSACVWVMMFVMLL 535 Query: 548 IGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-S 606 I +V +F+ FSP ++ +GR+ F I ++W G + + Sbjct: 536 IVSAVAVFVFEYFSPVGYN-RSLADGREPG----GPSFTIGKAIWLLWGLVFNNSVPVQN 590 Query: 607 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIA 660 P+ + +I+ VW FF +I ++SYTANLAAF+ E V + D Q Sbjct: 591 PKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFR 650 Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720 +GT+ GST+ R + + +M YM R ++ ++ ++ K A++ ++ Sbjct: 651 FGTVPNGSTERNIRNN----YAEMHAYMGKFNQ----RGVDDALLSLKTGKLD-AFIYDA 701 Query: 721 TMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777 + Y+ R + C + +G S GYGIA K S + V+LA+L+L G +++L+ Sbjct: 702 AVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELE 761 Query: 778 SKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF 828 + W G C + ++ +S L N+AGVFY+ LG AM ++LI F Sbjct: 762 ALWL--TGIC--HNEKNEVMSSQLDCDNMAGVFYM----LGAAMALSLITF 804 >5UP2-B nrPDB Length = 831 Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 174/738 (23%), Positives = 321/738 (43%), Gaps = 96/738 (13%) Query: 132 ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN---WQVTAVNILTTTEEGYRML 188 +++I++ Y W F I G + T + + W+V L T+ + L Sbjct: 149 VMLNIMEEYDWHVFSVITSNFPGYRDFISFIKTTVDNSFVGWEVQNYITLDTSYTDAQTL 208 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248 Q L+K ++++ C + I + L G G+ +I+ +L Sbjct: 209 TQ-LKKIHSSVILLYCSKDEATYIFEEARSLGLMGYGFVWIVPSL--------------- 252 Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLR 308 VTG TD IP S + DW A DG+ ++ A ++ Sbjct: 253 -VTG-----NTDIIPYEF-----PSGLVSVSYDDWDYG--IEARVRDGLGIITTAASAML 299 Query: 309 RQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHV 368 + I + C + + V ++G ++ F E G + N L V Sbjct: 300 EKHSVIPEAKTS--CYGQNERNDPPLHTLHNFMINVTWDG--KDLSFTEDGYQANPKLVV 355 Query: 369 IEMKHD-GIRKIGYW-----------------NEDDKFVPAATDAQAGGDNSSVQNRTYI 410 + + + K+G W + DD + T +A V+N Y+ Sbjct: 356 LLLNMEREWEKVGKWEAKSLNMKYPVWPRIDSDHDDNHLSIVTLEEA--PFVIVENIDYL 413 Query: 411 VTTILEDP-----YVMLKKNANQFEGNDRY-EGYCVELAAEIAKHVGYSYRLEIVSDGKY 464 T + + Y L + + + +G+C+++ +++K V ++Y L +V++GK+ Sbjct: 414 TGTCVRNTVPCRKYFRLANSTTEGTSVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKH 473 Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524 G + + WNGM+GE+VY RA +AV LTI R +DFS PF+ GIS+M+ + + Sbjct: 474 GKKIKN--VWNGMIGEVVYKRAVMAVGSLTINEERSVAVDFSVPFVETGISVMVSRSAGT 531 Query: 525 -KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQS 582 P +FL+P + +W M V + ++ +F+ FSP ++ +G+D Sbjct: 532 VSPS--AFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFSPVG-YNRNLAQGKDP----HG 584 Query: 583 NEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVE 641 F I ++W G + +P+ + +I+ +W FF +I ++SYTANLAAF+ Sbjct: 585 PSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWAFFAVIFLASYTANLAAFMIQR 644 Query: 642 RMVSPIESAEDLAKQTEIAY------GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695 R V + D Q Y GT+ GST+ R + + M YM Sbjct: 645 RFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIRNN----YPDMHQYMVKFHQ-- 698 Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPK 752 + ++ ++ ++ K A++ ++ + Y+ R + C + +G + GYGIA K Sbjct: 699 --KGVQDALVSLKTGKLD-AFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQK 755 Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYI 812 GS + P++LA+L+ G +++L+ W G C ++ ++ +S L + N+AGVFY+ Sbjct: 756 GSRWKRPIDLALLQFVGDGEMEELEKLWL--TGICHTEK--NEVMSSQLDIDNMAGVFYM 811 Query: 813 LIGGLGLAMLVALIEFCY 830 L + L+++ + E + Sbjct: 812 LAAAMALSLITFVWEHLF 829 >1YAE-A nrPDB Length = 312 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 94/207 (45%), Positives = 126/207 (60%), Gaps = 25/207 (12%) Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462 S+ NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DG Sbjct: 9 SLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDG 68 Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 522 KYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +KP Sbjct: 69 KYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPN 128 Query: 523 KSKPGVFSFL--------------------DPLAYEIWMCIVFAYIGVSVVLFLVSRFSP 562 + PGVFSFL D LA + + G ++ F S+ S Sbjct: 129 GTNPGVFSFLNGGSLVPRGSERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKIST 188 Query: 563 YE--WHSEEFEEGRDQTTSDQSNEFGI 587 Y+ W F R Q+ +SNE GI Sbjct: 189 YDKMWA---FMSSRRQSVLVKSNEEGI 212 Score = 154 bits (389), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 79/165 (47%), Positives = 112/165 (67%), Gaps = 7/165 (4%) Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT 700 ERM SPI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208 Query: 701 EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPV 760 EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265 Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSN 805 +A+L+L E+G L +K KWW G C ++S + SAL + N Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQN 306 >5DT6-A nrPDB Length = 267 Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 82/143 (57%), Positives = 105/143 (73%), Gaps = 1/143 (0%) Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704 +PI++ EDL QT++ YGTL GST EFFRRS+I + KMW YM +A V T +EG+ Sbjct: 125 TPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSVHTYDEGI 183 Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764 RVR+SKGKYA L+ES NEY+ R PCDTMKVG N+D+KG+G+ATP GS LR +N AV Sbjct: 184 RRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAV 243 Query: 765 LKLSEQGVLDKLKSKWWYDKGEC 787 L L E G L ++++KWW+DK EC Sbjct: 244 LTLKENGELLRIRNKWWFDKTEC 266 Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 63/119 (52%), Positives = 84/119 (70%), Gaps = 3/119 (2%) Query: 405 QNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462 +N TYIV+++LE+PY+ LK+ GNDR+EGYC +LA +A +G Y + +V DG Sbjct: 5 RNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDG 64 Query: 463 KYGARDPDTKA-WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 YGA + W+GMVGEL+ AD+A++ +TIT RE VIDFSKPFM+LGISIMIKK Sbjct: 65 NYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKK 123 >5L2E-A nrPDB Length = 688 Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 123/538 (22%), Positives = 245/538 (45%), Gaps = 55/538 (10%) Query: 25 IQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCSQF 78 I IG +F ++ FR A+ L + ++L + V+ ++ F+ C Sbjct: 6 IHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELM 65 Query: 79 SKGVYAIFGFYERRTVNMLTSFCGALHV----------------CFITPSFPVDTSNQFV 122 ++G+ A+ + L S A+H+ C +T S + ++ + Sbjct: 66 NQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRS---NRNDDYT 122 Query: 123 LQLRPE--LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTT 180 L +RP L E ++ ++ Y WQ F+ YD++ + +Q LD +++ V + Sbjct: 123 LSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 182 Query: 181 TEEGYRMLF-----QDLEKKKE--RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANL 233 + LF ++L + ++ R ++ + + ++V+ H+I+ N Sbjct: 183 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINE 242 Query: 234 GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQ-WRTSDARDHTRVDWKRP-----K 287 D+D+ + ++ ++ T +P I Q+ +R + T D K P + Sbjct: 243 EINDVDVQELVRR--SIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNME 300 Query: 288 YTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347 ++ YD V ++A AF + R S + C+ + PW G + +++ Sbjct: 301 ISNLYIYDTVLLLANAFHKKLQDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGVN 358 Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHD-----GIRKIGYWNEDDKFVPAATDAQAGGDNS 402 GLTG+++F E G N ++ + G+RK+G WN + TD + + Sbjct: 359 GLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMR 418 Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462 V R V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D Sbjct: 419 GVVLR---VVTVLEEPFVMVSENV--LGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDH 473 Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 KYG+ D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++ Sbjct: 474 KYGSPQED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 530 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 10/154 (6%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAEPSV 695 R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + S Sbjct: 529 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSE 588 Query: 696 F-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753 V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA G Sbjct: 589 NNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 646 Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787 S R + +L+L + G +D LK KWW G+C Sbjct: 647 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 680 >5EHM-A nrPDB Length = 268 Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 81/149 (54%), Positives = 105/149 (70%), Gaps = 4/149 (2%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PIESAEDLAKQT I YG L+ GST FFR SKI+ +++MW++M+SA PSVF + Sbjct: 120 RKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNG 179 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RV K KG YA+L+EST EY+ +R C+ +VGG LD+K YGIATP S R +N Sbjct: 180 EGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAIN 238 Query: 762 LAVLKLSEQGVLDKLKSKWWYDK---GEC 787 +LKL E+G L LK+KWW +K G+C Sbjct: 239 SVILKLQEEGKLHILKTKWWKEKRGGGKC 267 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 58/120 (48%), Positives = 92/120 (76%) Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460 +++++N+T +VTTIL +PY M K++A GND++EGY V+L EI+K +G++Y++++V Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61 Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121 >2XXT-A nrPDB Length = 261 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/186 (46%), Positives = 117/186 (62%), Gaps = 14/186 (7%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYG Sbjct: 3 NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYG 62 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQK 523 A+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K P Sbjct: 63 AQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGTPID 122 Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTTSDQ 581 S D LA + + G ++ F S+ S Y+ W F R Q+ + Sbjct: 123 SA-------DDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWA---FMSSRRQSVLVK 172 Query: 582 SNEFGI 587 SNE GI Sbjct: 173 SNEEGI 178 Score = 145 bits (367), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 70/144 (48%), Positives = 100/144 (69%), Gaps = 3/144 (2%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ E Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNE 175 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 176 EGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 232 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785 +A+L+L E+G L +K KWW G Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256 >5IKB-A nrPDB Length = 257 Score = 153 bits (387), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 76/146 (52%), Positives = 100/146 (68%), Gaps = 4/146 (2%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PIES +DLA QT I YGT+ GS+ FF+ S+ +++MW YM S +PSVFV++TE Sbjct: 115 RKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTE 174 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RV S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R + Sbjct: 175 EGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFD 231 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGEC 787 LA+L+L E L+ LK KWW + G+C Sbjct: 232 LAILQLQENNRLEILKRKWW-EGGKC 256 Score = 140 bits (352), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 76/161 (47%), Positives = 107/161 (66%), Gaps = 10/161 (6%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 N T +VTTILE+PY+MLK N EGNDRYEG+CV++ E+A+ + ++Y++ +V DG YG Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQK 523 + + W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K P + Sbjct: 63 VPEAN-GTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTPIE 121 Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564 S +D LA + + + G S+ F SR+ Y+ Sbjct: 122 S-------VDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQ 155 >4MF3-A nrPDB Length = 261 Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 92/202 (45%), Positives = 124/202 (61%), Gaps = 15/202 (7%) Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462 S+ NRT IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y +++V DG Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60 Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK-- 520 KYGA++ D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 61 KYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGT 119 Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHSEEFEEGRDQTT 578 P S D LA + + G ++ F S+ S YE W F R QT Sbjct: 120 PIDSA-------DDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMW---AFMSSRQQTA 169 Query: 579 SDQSNEFGIFNSLWFSLGAFMQ 600 ++++ GI L M+ Sbjct: 170 LVRNSDEGIQRVLTTDYALLME 191 Score = 142 bits (358), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 69/144 (47%), Positives = 98/144 (68%), Gaps = 3/144 (2%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PI+SA+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + + VR ++ Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSD 175 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 176 EGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKIT 232 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785 +A+L+L E+G L +K KWW G Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256 >4IGR-A nrPDB Length = 258 Score = 149 bits (375), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 68/115 (59%), Positives = 91/115 (79%), Gaps = 1/115 (0%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 NR+ IVTT+LE+P+VM +K+ GNDR+EGYC++L E+A +G+SY + +V DGKYG Sbjct: 5 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYG 64 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 A+D D WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K Sbjct: 65 AQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRK 118 Score = 140 bits (354), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 71/144 (49%), Positives = 98/144 (68%), Gaps = 4/144 (2%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ FEKMW +M S++PS V+ E Sbjct: 117 RKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVKNNE 175 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ R + YA L+EST EYI QR C+ ++GG +DSKGYGI TP GS R + Sbjct: 176 EGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRDKIT 232 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKG 785 +A+L+L E+ L +K KWW G Sbjct: 233 IAILQLQEEDKLHIMKEKWWRGSG 256 >4WXJ-A nrPDB Length = 269 Score = 102 bits (254), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 1/137 (0%) Query: 645 SPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGM 704 + I S DL Q ++ +GT+ G+T +F S W M S +P F + EEG+ Sbjct: 126 TDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGV 185 Query: 705 IRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAV 764 RV+ SKG YA+L+E+T +Y QR C+ ++G + K YGIA P + R +++ + Sbjct: 186 DRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRSNLSVGI 244 Query: 765 LKLSEQGVLDKLKSKWW 781 L+LSE+G L KL++KW+ Sbjct: 245 LRLSERGELFKLRNKWF 261 Score = 93.6 bits (231), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 44/114 (38%), Positives = 67/114 (58%), Gaps = 2/114 (1%) Query: 409 YIVTTILEDPYVMLKKNAN--QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 Y V T + PY ++ +EGN+R+EGY V+L +A+ + + E V D KYG+ Sbjct: 11 YTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGS 70 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 D +T W+G++ +L+ A + + LTIT R V+DF+ PFM LGISI+ K Sbjct: 71 YDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYK 124 >5CC2-A nrPDB Length = 265 Score = 89.0 bits (219), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 38/110 (34%), Positives = 72/110 (65%), Gaps = 3/110 (2%) Query: 411 VTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPD 470 V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D KYG+ D Sbjct: 7 VVTVLEEPFVMVSENV--LGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQED 64 Query: 471 TKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++ Sbjct: 65 -GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 113 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 10/154 (6%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAEPSV 695 R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + S Sbjct: 112 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSE 171 Query: 696 F-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753 V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA G Sbjct: 172 NNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 229 Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787 S R + +L+L + G +D LK KWW G+C Sbjct: 230 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 263 >5I2K-B nrPDB Length = 293 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 38/88 (43%), Positives = 64/88 (72%), Gaps = 4/88 (4%) Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAP 492 G+C++L ++A+ + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAP Sbjct: 66 GFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 125 Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKK 520 LTI R + I+FSKPF G++I++KK Sbjct: 126 LTINNERAQYIEFSKPFKYQGLTILVKK 153 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720 Y T++ S +FRR M+ +M+ + E + VR +K +A++ +S Sbjct: 174 YATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDS 226 Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780 + E+ E + CD + G G+GI K S + V+L++LK E G ++ L K Sbjct: 227 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DKT 284 Query: 781 WYDKGECGS 789 W EC S Sbjct: 285 WVRYQECDS 293 >3OEK-A nrPDB Length = 286 Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 36/85 (42%), Positives = 59/85 (69%), Gaps = 2/85 (2%) Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 +G+C+++ +A +G+SY L +V++GK+G + WNGM+GE+ Y RAD+A+ LTI Sbjct: 60 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKI--DGVWNGMIGEVFYQRADMAIGSLTI 117 Query: 496 TLVREEVIDFSKPFMSLGISIMIKK 520 R E++DFS PF+ GIS+M+ + Sbjct: 118 NEERSEIVDFSVPFVETGISVMVAR 142 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/126 (25%), Positives = 66/126 (52%), Gaps = 14/126 (11%) Query: 659 IAYGTLEAGSTKEFFRRSKIAVFEKMWTYM-KSAEPSVFVRTTEEGMIRVRKSKGKYAYL 717 + +GT+ GST++ R + + M +YM + +P V EE + +++ K A++ Sbjct: 164 LKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGKLD-AFI 213 Query: 718 LESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLD 774 ++ + Y+ ++ + C + +G + GYGIA KGS + P++LA+L+ ++ Sbjct: 214 YDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIE 273 Query: 775 KLKSKW 780 L+ W Sbjct: 274 MLERLW 279 >5H8N-A nrPDB Length = 285 Score = 82.4 bits (202), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 36/85 (42%), Positives = 60/85 (70%), Gaps = 2/85 (2%) Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 +G+C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI Sbjct: 59 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 116 Query: 496 TLVREEVIDFSKPFMSLGISIMIKK 520 R EV+DFS PF+ GIS+M+ + Sbjct: 117 NEERSEVVDFSVPFVETGISVMVSR 141 Score = 38.5 bits (88), Expect = 0.013, Method: Compositional matrix adjust. Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 12/123 (9%) Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720 +GT+ GST+ R + + YM + E+ ++ ++ K A++ ++ Sbjct: 165 FGTVPNGSTERNIRNN--------YPYMHQYMTKFNQKGVEDALVSLKTGKLD-AFIYDA 215 Query: 721 TMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLK 777 + Y R + C + +G + GYGIA KGS + ++LA+L+ G +++L+ Sbjct: 216 AVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELE 275 Query: 778 SKW 780 + W Sbjct: 276 TLW 278 >2RCB-A nrPDB Length = 292 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 36/84 (42%), Positives = 54/84 (64%), Gaps = 4/84 (4%) Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGA-RDPDTKAWNGMVGELVYGRADVAVAPLTI 495 GYC++L +A+ + + + L IV DGKYGA RD W G+VG+L+ GRA +AV +I Sbjct: 68 GYCIDLLERLAEDLAFDFELYIVGDGKYGALRD---GRWTGLVGDLLAGRAHMAVTSFSI 124 Query: 496 TLVREEVIDFSKPFMSLGISIMIK 519 R +V+DF+ PF S + IM++ Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVR 148 Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 11/130 (8%) Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY-AYLLE 719 +GT+ S + + + A F +M +M+ TT G+ + K A++++ Sbjct: 171 FGTVWESSAEAYIK----ASFPEMHAHMRRHS----APTTPHGVAMLTSDPPKLNAFIMD 222 Query: 720 STMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778 ++ +Y + C + VG +GYGI P+ S L ++ + + G +D L Sbjct: 223 KSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHD 282 Query: 779 KWWYDKGECG 788 K WY CG Sbjct: 283 K-WYKMVPCG 291 >2RC9-A nrPDB Length = 294 Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 33/83 (39%), Positives = 53/83 (63%), Gaps = 2/83 (2%) Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496 GYC++L ++A+ + + + L IV DGKYGA W G+VG+L+ G A++AV +I Sbjct: 70 GYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NGHWTGLVGDLLSGTANMAVTSFSIN 127 Query: 497 LVREEVIDFSKPFMSLGISIMIK 519 R +VIDF+ PF S + I+++ Sbjct: 128 TARSQVIDFTSPFFSTSLGILVR 150 Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 10/123 (8%) Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY-AYLLE 719 +GT+ S +++ R+S F +M YM+ V T +G+ ++ K A++++ Sbjct: 173 FGTVRESSAEDYVRQS----FPEMHEYMRRYN----VPATPDGVQYLKNDPEKLDAFIMD 224 Query: 720 STMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778 + +Y + C + VG +GYGI P S L ++ + + G +D L Sbjct: 225 KALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHD 284 Query: 779 KWW 781 KW+ Sbjct: 285 KWY 287 >4YKP-A nrPDB Length = 256 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 3/137 (2%) Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 R + ++ E P++ EGND + G ++ ++++ +G++Y D K+GA Sbjct: 8 RHLRLGSVEEQPFMFFATEG--CEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGA 65 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526 + T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K + Sbjct: 66 LNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLN 125 Query: 527 GVFSFLDPLAYEIWMCI 543 V LD Y+ W I Sbjct: 126 QVLELLDQDKYK-WGVI 141 Score = 36.2 bits (82), Expect = 0.059, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 23/49 (46%) Query: 732 CDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780 CD VG S Y PK S + ++ +LK E+G +D L KW Sbjct: 200 CDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKW 248 >5TUJ-C nrPDB Length = 235 Score = 56.2 bits (134), Expect = 7e-08, Method: Composition-based stats. Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 13/102 (12%) Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491 N +Y G+ ++LA +AK +G ++E V P T W+G++ L G+ D+ ++ Sbjct: 31 NGQYTGFDIDLAKALAKELGV--KVEFV---------PTT--WDGIIPALQTGKFDIVMS 77 Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 533 +TIT R++ +DFS P+M+ G +I++KK K F L+ Sbjct: 78 GMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLN 119 Score = 29.3 bits (64), Expect = 9.0, Method: Composition-based stats. Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 22/140 (15%) Query: 647 IESAEDLAK---QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEG 703 I+S EDL K + + GT + KEF ++KI FE E Sbjct: 112 IKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE----------------NNAEA 155 Query: 704 MIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKGSA-LRGPVN 761 V + A + +S + Y ++ P + V + G A KG L VN Sbjct: 156 FQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKGDPELLNWVN 214 Query: 762 LAVLKLSEQGVLDKLKSKWW 781 + ++ + G DKL KW+ Sbjct: 215 NWLKQMKKDGTYDKLYEKWF 234 >4ZDM-A nrPDB Length = 261 Score = 55.1 bits (131), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 47/85 (55%) Query: 435 YEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLT 494 Y G VE+ + +++ + ++Y D K+G ++ T WNG++ +L+ + D+ V L+ Sbjct: 37 YTGVNVEIVSMMSQDLNFTYNFITPEDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALS 96 Query: 495 ITLVREEVIDFSKPFMSLGISIMIK 519 VR+ IDFS M G+ ++K Sbjct: 97 NNAVRKADIDFSLSMMDGGLGALVK 121 Score = 33.5 bits (75), Expect = 0.46, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 687 YMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGY 746 Y + AE +V V + EG+ R+R G + ++ E Y + CD +++G Sbjct: 161 YNRIAEDAVKVGSYGEGLERMRA--GGFVFIDEIPGINY-ATKGECDIVQIGETFQPFEL 217 Query: 747 GIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784 K S + V+ +L + EQGV+ +L +K+ K Sbjct: 218 AFGLRKNSPFKNLVDTFMLGIREQGVISELYAKYENQK 255 >4F3P-A nrPDB Length = 249 Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 13/92 (14%) Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487 +F+ D+Y G+ ++L AEIAK G++Y+++ + + G++ L D Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 VA++ +TI R + IDFS P+ G++ M++ Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQ 116 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 737 VGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781 G + YGI PKGS L VN + ++ G K+ KW+ Sbjct: 197 AGAPVSGDKYGIGFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241 >4PSH-A nrPDB Length = 227 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 34/131 (25%), Positives = 66/131 (50%), Gaps = 22/131 (16%) Query: 404 VQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461 +++R Y++ + D P+ + +N N G+ V+LA EIA+ +G L+IV Sbjct: 5 IKSRGYLLVGLSADFPPFEFVDENGNIV-------GFDVDLAKEIARRLGV--ELKIVD- 54 Query: 462 GKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 521 ++G++ L+ + DV ++ +TIT R++V+ FS P+ G I+++K Sbjct: 55 ----------MTFDGLIPSLLTKKIDVIISGMTITEERKKVVAFSDPYFDAGQVIVVRKD 104 Query: 522 QKSKPGVFSFL 532 +P + L Sbjct: 105 SDFRPKTYEDL 115 >4ZV2-A nrPDB Length = 233 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%) Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491 N + G+ ++LA IAK +G + + ++G++ L G+ DV +A Sbjct: 29 NGKLVGFDIDLAKAIAKKLGVKVEFKPMD-------------FDGIIPALQSGKIDVVIA 75 Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524 +TIT R++ +DFS P+ G +I++KK S Sbjct: 76 GMTITEERKKQVDFSDPYFEAGQAIVVKKGNDS 108 Score = 32.3 bits (72), Expect = 0.87, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 725 YIEQRKPCDTMKVGGNLDSKGYGIATPKG-SALRGPVNLAVLKLSEQGVLDKLKSKWW 781 Y++Q VG + YGIA KG S L +N A+ ++ + G DK+ KW+ Sbjct: 174 YVKQNPNAGVKIVGETFSGEPYGIAVRKGNSELLEKINKALEEMKKDGTYDKIYEKWF 231 >4IO3-A nrPDB Length = 248 Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 32/61 (52%) Query: 724 EYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783 EY+ C+ VG + D +GI TPK +++ +L L E G+LD LK KW+ Sbjct: 185 EYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQT 244 Query: 784 K 784 K Sbjct: 245 K 245 Score = 36.6 bits (83), Expect = 0.049, Method: Compositional matrix adjust. Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 9/87 (10%) Query: 434 RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPL 493 + GY ++L + +G+ +++ P ++ G+V L G D+A+ + Sbjct: 36 KLTGYVLDLIEYLRDKMGFVADVQLA---------PPNTSYTGLVLALANGDYDIAIGDI 86 Query: 494 TITLVREEVIDFSKPFMSLGISIMIKK 520 T+T R E++ FS + I+++K Sbjct: 87 TVTSARREIVAFSNSISDNSMRILMRK 113 >4F3S-A nrPDB Length = 255 Score = 45.8 bits (107), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 19/37 (51%), Positives = 30/37 (81%) Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPF 509 AW+GM+G + G+ADVA + ++IT R++VIDFS+P+ Sbjct: 56 AWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPY 92 >3K4U-A nrPDB Length = 245 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 30/160 (18%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 P+ M K N G+ V+LA E+AK +G +L S W+G+ Sbjct: 17 PFEMKDKKGNVI-------GFDVDLAREMAKAMGVKLKLVPTS-------------WDGL 56 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537 + LV + D+ ++ +TI+ R ++F +P++ +G S+++KK + GV S+ D Sbjct: 57 IPGLVTEKFDIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEK--GVKSYKDLDKP 114 Query: 538 EIWMCIVFAYIGVSVV-----LFLVSRFSPYEWHSEEFEE 572 E+ + F GVS LF ++ Y+ +E +E Sbjct: 115 ELTLVTKF---GVSAEYAAKRLFKNAKLKTYDTEAEAVQE 151 >1GGG-A nrPDB Length = 226 Score = 44.3 bits (103), Expect = 3e-04, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487 +F+ D Y G+ V+L A IAK + Y L+ + ++G++ L D Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 +A+A +TIT R++ IDFS + G+ +M+K Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVK 95 Score = 40.4 bits (93), Expect = 0.004, Method: Composition-based stats. Identities = 21/46 (45%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Query: 737 VGGNLDSKGYGIATPKGS-ALRGPVNLAVLKLSEQGVLDKLKSKWW 781 VG +L+++ YGIA PKGS LR VN A+ L E G +++ KW+ Sbjct: 176 VGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWF 221 >5JOS-A nrPDB Length = 247 Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 13/92 (14%) Query: 434 RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPL 493 +Y G+ +++A +AK +G ++E V P T W ++ +L + D+A+ + Sbjct: 44 QYTGFDIDVAKSLAKSLGV--KVEFV---------PTT--WPTLMSDLQADKFDIAMGGV 90 Query: 494 TITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525 T+T R++ DFS P+M+ G + +++K K Sbjct: 91 TVTPERQKKADFSDPYMTFGKTPLVRKEDADK 122 >4H5F-A nrPDB Length = 243 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 13/96 (13%) Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 +G ++ G +++A IA +G +LEI+S +++ ++ L G+AD+A Sbjct: 32 DGKNQVVGADIDMAQAIADELGV--KLEILS-----------MSFDNVLTSLQTGKADLA 78 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525 VA ++ T R+EV DFS P+ IS ++ K K Sbjct: 79 VAGISATDERKEVFDFSIPYYENKISFLVHKADVEK 114 >2PYY-A nrPDB Length = 228 Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust. Identities = 20/49 (40%), Positives = 24/49 (48%) Query: 737 VGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKG 785 VG L + YGI P S R P+N A+L L E G L KW+ K Sbjct: 177 VGSILREESYGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWFDPKN 225 Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 20/110 (18%) Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469 +V T + P+V+ K G+ ++L IA +G +L Sbjct: 6 LVATRVIPPFVLSNKG--------ELSGFSIDLWRSIATQIGIESKLI------------ 45 Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 + + ++ + + ++ +A ++IT RE+ DFS P + G+ IM++ Sbjct: 46 EYSSVPELISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95 >5OTA-A nrPDB Length = 265 Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 26/39 (66%) Query: 472 KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510 +AW+G++ L GR D +A + I RE+VI FS+P++ Sbjct: 51 QAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYL 89 >4MS4-A nrPDB Length = 420 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 337 IQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE-DDKFVPAATDA 395 I RA+ FEG++G+V F+ G R +TL + +++ +KIGY++ D + TD Sbjct: 345 IYRAMNSSSFEGVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYDSTKDDLSWSKTDK 403 Query: 396 QAGG 399 GG Sbjct: 404 WIGG 407 >4YMX-A nrPDB Length = 260 Score = 37.4 bits (85), Expect = 0.030, Method: Composition-based stats. Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 13/76 (17%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G D G+ +++A IAK +G +LEI +D D K G++ L GR D+ + Sbjct: 58 GKDEIVGFDIDIANAIAKKLGV--KLEI--------KDMDFK---GLIPALQAGRVDMVI 104 Query: 491 APLTITLVREEVIDFS 506 A +T T R++ +DFS Sbjct: 105 AGMTPTAERKKSVDFS 120 >4ZEF-A nrPDB Length = 251 Score = 37.4 bits (85), Expect = 0.031, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 24/37 (64%) Query: 484 GRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 G+AD VA +TIT R++ DFS P+ GI I +KK Sbjct: 86 GQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKK 122 >4I62-A nrPDB Length = 269 Score = 37.0 bits (84), Expect = 0.036, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 13/91 (14%) Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 +G ++ G +ELA IA +G L +S ++ ++ + G+AD+A Sbjct: 59 DGKNQIVGSDIELAKAIATELGVELELSPMS-------------FDNVLASVQSGKADLA 105 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 ++ ++ T R +V DFS P+ + +++KK Sbjct: 106 ISGVSKTDERSKVFDFSTPYYTAKNKLIVKK 136 >6FXG-A nrPDB Length = 227 Score = 35.4 bits (80), Expect = 0.13, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 13/93 (13%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G ++ G V++ E+AK ++LE+ G ++ + L G+ D + Sbjct: 22 GQKKWVGIDVDIMQEVAKI--NDWKLEMSYPG-----------FDAALQNLKAGQVDGII 68 Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523 A +TIT R+E DFS P+ + ++I K K Sbjct: 69 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 101 >4KPT-A nrPDB Length = 251 Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 13/93 (13%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G ++ G V++ E+AK ++LE+ G ++ + L G+ D + Sbjct: 46 GQKKWVGIDVDIMQEVAKI--NDWKLEMSYPG-----------FDAALQNLKAGQVDGII 92 Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523 A +TIT R+E DFS P+ + ++I K K Sbjct: 93 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 125 >5LOM-A nrPDB Length = 269 Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 17/100 (17%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 PY + N + G+ +EL +A +G+ + + ++ A P Sbjct: 43 PYAFTTADGN-------FTGFDIELFLNVAGRLGFKKEQVVFTGQEFSALMP-------- 87 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIM 517 + GR DVA A + T R+E +DFS +++ +S++ Sbjct: 88 --SVANGRFDVAAAAIGTTAKRKETVDFSDGYLAGFLSVL 125 >2IEE-A nrPDB Length = 271 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 14/90 (15%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G+D+ GY VE+ E AK +G + +GM+ + G+ D A Sbjct: 42 GSDKLTGYEVEVVREAAKRLGLKVEFK-------------EMGIDGMLTAVNSGQVDAAA 88 Query: 491 APLTITLVREEVIDFSKPF-MSLGISIMIK 519 + +T REE FS P+ S G +I+ K Sbjct: 89 NDIDVTKDREEKFAFSTPYKYSYGTAIVRK 118 >3I6V-A nrPDB Length = 232 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 25/37 (67%) Query: 474 WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510 W+ ++ LV G D +A ++IT R+EVIDF++ ++ Sbjct: 53 WDSIIPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89 >2Q2A-A nrPDB Length = 272 Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust. Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 13/84 (15%) Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496 G+ V+L + K G Y L+ + W+ + L D+ ++ +TIT Sbjct: 65 GFDVDLLDAVMKAAGLDYELKNI-------------GWDPLFASLQSKEVDMGISGITIT 111 Query: 497 LVREEVIDFSKPFMSLGISIMIKK 520 R++ DFS P+ I++K+ Sbjct: 112 DERKQSYDFSDPYFEATQVILVKQ 135 >3EIQ-A nrPDB Length = 414 Score = 33.1 bits (74), Expect = 0.52, Method: Compositional matrix adjust. Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Query: 501 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 556 +V++ +K FM I I++KK + + G+ F + E W +C ++ + ++ + Sbjct: 227 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 286 Query: 557 VSRFSPYEWHSEEFEEGRDQTTS 579 ++ +W +E+ RD T S Sbjct: 287 INTRRKVDWLTEKM-HARDFTVS 308 >4OEN-A nrPDB Length = 223 Score = 32.7 bits (73), Expect = 0.70, Method: Compositional matrix adjust. Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 22/142 (15%) Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491 +++Y G +EL IAK G+ +EI + G ++ + + G+AD +A Sbjct: 22 SNQYTGIDMELIKAIAKDQGF--EIEITNPG-----------FDAAISAVQAGQADGIIA 68 Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551 +++T R+ DFS+ + + + +K+ + S+ D + V G + Sbjct: 69 GMSVTDARKATFDFSESYYTANTILGVKESSN----IASYED-----LKGKTVGVKNGTA 119 Query: 552 VVLFLVSRFSPYEWHSEEFEEG 573 FL S Y + + F +G Sbjct: 120 SQTFLTENQSKYGYKIKTFADG 141 >3TQL-A nrPDB Length = 227 Score = 32.7 bits (73), Expect = 0.75, Method: Compositional matrix adjust. Identities = 12/49 (24%), Positives = 26/49 (53%) Query: 472 KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 + W+ ++ L G+ D + IT R++ +DF+ P+ + +S + K Sbjct: 48 QPWDSLIPSLKLGKFDALFGGMNITTARQKEVDFTDPYYTNSVSFIADK 96 >5ORE-A nrPDB Length = 263 Score = 32.3 bits (72), Expect = 0.96, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Query: 474 WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMS--LGISIMIKKPQKSKPGV 528 W+G++ L + D +A +++T R+EVI FS P+ + G ++M PG+ Sbjct: 52 WDGIMPSLTGKKYDAIMAAMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGL 108 >2HYI-C nrPDB Length = 413 Score = 32.0 bits (71), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/77 (18%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 501 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 556 E+++ + FM+ I I++K+ + + G+ F + E W +C ++ + ++ + Sbjct: 224 EILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIF 283 Query: 557 VSRFSPYEWHSEEFEEG 573 + +W +E+ E Sbjct: 284 CNTKRKVDWLTEKMREA 300 >5EYF-A nrPDB Length = 245 Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525 L G D +A +TIT R++ +DFS + G ++++KK + K Sbjct: 74 LKNGNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIK 118 Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 737 VGGNLDSKGYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGE 786 VGG ++ YGIA KG VN A+ ++ G DK+ KW+ ++ E Sbjct: 191 VGGTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETE 241 >5HPQ-A nrPDB Length = 255 Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 22/109 (20%) Query: 435 YEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLT 494 Y G+ V++A +A+ +G +L +V +W ++ + R D+A++ ++ Sbjct: 45 YAGFDVDMAQRLAESLGA--KLVVVP-----------TSWPNLMRDFADDRFDIAMSGIS 91 Query: 495 ITLVREEVIDFSKPFMSLG---ISIMIKKP------QKSKPGVFSFLDP 534 I L R+ FS P++ G I++ ++ Q +PGV + ++P Sbjct: 92 INLERQRQAYFSIPYLRDGKTPITLCSEEARFQTLEQIDQPGVTAIVNP 140 >5VXG-A nrPDB Length = 358 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 15/101 (14%) Query: 579 SDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLS-GRIVGGVWWFFTLIIISSYTANLAAF 637 SD F + N+ AF+ G DI+ R L G I +++ TANL Sbjct: 131 SDHCMTFDVANACL----AFIN-GMDIAARMLERGEI-------DYALVVDGETANLVYE 178 Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKI 678 T+ERM SP + E+ + E+A TL G+ RS++ Sbjct: 179 KTLERMTSPDVTEEEF--RNELAALTLGCGAAAMVMARSEL 217 >3F41-A nrPDB Length = 629 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 13/81 (16%) Query: 184 GYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKF 243 G ++ +L+K K + +D + ++ +++ + +EKNG+ Y+ I A + Sbjct: 462 GKSLIVAELDKDK---MPIDPKPVKIESVMTEQQLVEKNGLHYYRIAAT--------DHI 510 Query: 244 KESGANVTGFQLVNYTDTIPA 264 S AN+ F +N+T T+PA Sbjct: 511 WPSAANIDEF--INFTRTMPA 529 >6J0J-A nrPDB Length = 302 Score = 29.6 bits (65), Expect = 6.7, Method: Compositional matrix adjust. Identities = 38/165 (23%), Positives = 68/165 (41%), Gaps = 31/165 (18%) Query: 357 EKGRRTNYTLHVIEMKHD--GIRKIGYWN----EDDKFVPAATDAQAGGDNSSVQNRTYI 410 EK R+ Y L ++E++ + GI ++ Y + +F D Q GD ++ Sbjct: 117 EKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIA----- 171 Query: 411 VTTILEDPYVMLKKNANQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469 + K +F + D +GY AA ++ S + E+ ++ K ARD Sbjct: 172 -----------ISKEGVKFSSSGDVGQGYTFLQAAGVSDR---STKSEVKAEVKAEARDD 217 Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514 D + + YG+AD + + + + EE I S +GI Sbjct: 218 DEEPLSRK-----YGKADSSANAIGVEVTMEEPITLSFALRFMGI 257 >6F6P-A nrPDB Length = 106 Score = 29.3 bits (64), Expect = 8.0, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 24/41 (58%) Query: 176 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQI 216 ++L E+GY L ++L K + L + D E ERL+ + Q+ Sbjct: 10 SVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQL 50 >5GZU-A nrPDB Length = 885 Score = 29.3 bits (64), Expect = 9.1, Method: Compositional matrix adjust. Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 19/113 (16%) Query: 718 LESTMNEYIEQRKPCDTMKVGG--------NLDSKGYGIATPKGSALRGPVNLAVLKLSE 769 ++ST+ Y+ P + + VGG N+++KG G++ GS P + +L Sbjct: 259 VDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGLSEKAGSQAGSPGTIVYSELVN 318 Query: 770 QGVLDKLKSKWWYDKGEC-----GSKDSGSKDKTSA------LSLSNVAGVFY 811 + +++W D + GS +D SA + +N+AG Y Sbjct: 319 NYINKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGFMY 371 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6QKC-A nrPDB 1344 0.0 5IDF-B nrPDB 1098 0.0 4U1Y-A nrPDB 1085 0.0 5KUF-A nrPDB 983 0.0 5IPR-B nrPDB 744 0.0 5UOW-A nrPDB 742 0.0 6IRA-D nrPDB 740 0.0 4PE5-B nrPDB 730 0.0 5FXI-A nrPDB 727 0.0 5UP2-B nrPDB 725 0.0 5KUH-A nrPDB 612 e-175 5L2E-A nrPDB 494 e-140 5UN1-G nrPDB 487 e-138 5UN1-B nrPDB 485 e-137 1YAE-A nrPDB 244 2e-64 2XXT-A nrPDB 228 8e-60 3FAT-A nrPDB 228 9e-60 5O9A-A nrPDB 228 1e-59 3DP4-A nrPDB 227 2e-59 4MF3-A nrPDB 225 6e-59 4IGR-A nrPDB 216 3e-56 5IKB-A nrPDB 205 6e-53 5EHM-A nrPDB 205 1e-52 5DT6-A nrPDB 197 2e-50 5CC2-A nrPDB 175 6e-44 4WXJ-A nrPDB 173 4e-43 5I2K-B nrPDB 164 1e-40 5H8N-A nrPDB 157 2e-38 4YKP-A nrPDB 154 2e-37 3OEK-A nrPDB 144 2e-34 2RC9-A nrPDB 143 3e-34 5TUJ-C nrPDB 131 2e-30 4ZDM-A nrPDB 120 3e-27 3K4U-A nrPDB 120 3e-27 2RCB-A nrPDB 120 4e-27 4PSH-A nrPDB 113 4e-25 4ZV2-A nrPDB 104 1e-22 5JOS-A nrPDB 104 2e-22 4F3P-A nrPDB 101 2e-21 1GGG-A nrPDB 98 2e-20 4IO3-A nrPDB 96 8e-20 4H5F-A nrPDB 91 2e-18 4F3S-A nrPDB 64 2e-10 Sequences not found previously or not previously below threshold: 4YMX-A nrPDB 85 1e-16 4G4P-A nrPDB 84 3e-16 4I62-A nrPDB 81 3e-15 2Q2A-A nrPDB 79 9e-15 4ZEF-A nrPDB 74 3e-13 2PYY-A nrPDB 70 5e-12 5HPQ-A nrPDB 69 9e-12 5X2N-B nrPDB 68 2e-11 4OEN-A nrPDB 68 2e-11 4KPT-A nrPDB 66 7e-11 6FXG-A nrPDB 66 8e-11 5EYF-A nrPDB 65 1e-10 4MS4-A nrPDB 62 9e-10 5X2M-A nrPDB 62 1e-09 4F11-A nrPDB 62 1e-09 4KQP-A nrPDB 61 2e-09 3TQL-A nrPDB 61 3e-09 2IEE-A nrPDB 60 5e-09 5OTA-A nrPDB 60 5e-09 2Y7I-A nrPDB 60 6e-09 3VV5-A nrPDB 59 9e-09 5K5S-A nrPDB 58 2e-08 5FBH-B nrPDB 58 2e-08 5LOM-A nrPDB 58 2e-08 5ORE-A nrPDB 57 3e-08 1HSL-A nrPDB 55 1e-07 3I6V-A nrPDB 54 3e-07 1IIT-A nrPDB 54 3e-07 1ISS-A nrPDB 54 3e-07 3DEL-B nrPDB 54 4e-07 5OWF-A nrPDB 52 8e-07 1YK0-A nrPDB 52 1e-06 3A3K-A nrPDB 46 6e-05 4Q0C-A nrPDB 42 0.001 2Q88-A nrPDB 41 0.003 4PX2-A nrPDB 33 0.46 4DX0-A nrPDB 33 0.72 4V8M-A5 nrPDB 32 1.2 5XXU-I nrPDB 32 1.7 5OPT-Z nrPDB 31 2.1 3AXY-C nrPDB 31 2.6 3IP9-A nrPDB 31 2.9 4V6W-AI nrPDB 30 4.9 2F6U-A nrPDB 30 5.5 5A5X-A nrPDB 29 8.6 >6QKC-A nrPDB Length = 915 Score = 1344 bits (3478), Expect = 0.0, Method: Composition-based stats. Identities = 905/915 (98%), Positives = 906/915 (99%), Gaps = 8/915 (0%) Query: 1 MPYIFAFFCTGFLGAVVGA--------NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 52 MPYIFAFFCTGFLGAVVGA NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP Sbjct: 1 MPYIFAFFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEP 60 Query: 53 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS Sbjct: 61 PKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 120 Query: 113 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 172 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV Sbjct: 121 FPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQV 180 Query: 173 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN Sbjct: 181 TAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 240 Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSD+RDHTRVDWKRPKYTSAL Sbjct: 241 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSAL 300 Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN Sbjct: 301 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 360 Query: 353 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 412 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT Sbjct: 361 VQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVT 420 Query: 413 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 472 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK Sbjct: 421 TILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK 480 Query: 473 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL Sbjct: 481 AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540 Query: 533 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 592 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLW 600 Query: 593 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660 Query: 653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 712 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG Sbjct: 661 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 720 Query: 713 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV Sbjct: 721 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 780 Query: 773 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS Sbjct: 781 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 840 Query: 833 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIP 892 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGG GSGENGRVVSQDFPKSMQSIP Sbjct: 841 RSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIP 900 Query: 893 CMSHSSGMPLGATGL 907 CMSHSSGMPLGATGL Sbjct: 901 CMSHSSGMPLGATGL 915 >5IDF-B nrPDB Length = 874 Score = 1098 bits (2840), Expect = 0.0, Method: Composition-based stats. Identities = 589/830 (70%), Positives = 691/830 (83%), Gaps = 11/830 (1%) Query: 21 FPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIVNISDSFEMTYR 73 FPN I IGGLF QEH+AFRFA+ + +P L +D ++ S+SF +T Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69 Query: 74 FCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEAL 133 FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D QFV+Q+RP L+ A+ Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129 Query: 134 ISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE-EGYRMLFQDL 192 +S++ +YKW+ FVY+YD +RG SVLQ +++ A + NWQVTA ++ + + +R + +++ Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189 Query: 193 EKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTG 252 ++++E+ ++DCE ER+N IL Q+V L K+ GYHY+LANLGF DI L + GAN+TG Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249 Query: 253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRI 312 FQ+VN + + + +Q+W D + KYTSALT+D + V+AEAF+ LRRQR+ Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309 Query: 313 DISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK 372 D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+ GRRTNYT+ V EMK Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369 Query: 373 HDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGN 432 G RK GYWNE ++FVP +D Q D+SS +NRT +VTTILE PYVM KKN Q EGN Sbjct: 370 VSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 428 Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492 +RYEGYCV+LA EIAKHVG Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAP Sbjct: 429 ERYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 488 Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 552 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV Sbjct: 489 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 548 Query: 553 VLFLVSRFSPYEWHSE-EFEEGRD-QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSL 610 VLFLVSRFSPYEWH E EE RD Q+ D NEFGIFNSLWFSLGAFMQQGCDISPRSL Sbjct: 549 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 608 Query: 611 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTK 670 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL++GSTK Sbjct: 609 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 668 Query: 671 EFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK 730 EFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+LLESTMNEYIEQRK Sbjct: 669 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 728 Query: 731 PCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790 PCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAVLKLSEQG+LDKLK+KWWYDKGECG+K Sbjct: 729 PCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 788 Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840 DSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ESKRMK Sbjct: 789 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 838 >4U1Y-A nrPDB Length = 819 Score = 1085 bits (2805), Expect = 0.0, Method: Composition-based stats. Identities = 587/825 (71%), Positives = 699/825 (84%), Gaps = 14/825 (1%) Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQIDIVNISDSFEMTYRFCSQFSKG 81 N+IQIGGLFP QE++AFR + Q T +L P ID + +++SF +T FCSQFS+G Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRG 60 Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYK 141 VYAIFGFY++++VN +TSFCG LHV FITPSFP D ++ FV+Q+RP+L+ AL+S+I++Y+ Sbjct: 61 VYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQ 120 Query: 142 WQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT----EEGYRMLFQDLEKKKE 197 W F Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+ +E YR LFQDLE KKE Sbjct: 121 WDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKE 180 Query: 198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257 R V++DCE +++N I+ Q++ + K+ GYHYI+ANLGF D DL K + GA V+GFQ+V+ Sbjct: 181 RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVD 240 Query: 258 YTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRR 317 Y D++ ++ +++W T + +++ KYTSALTYD V+VM EAF++LR+QRI+ISRR Sbjct: 241 YDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRR 300 Query: 318 GNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIR 377 GNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F++ G+R NYT++++E+K +G R Sbjct: 301 GNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPR 360 Query: 378 KIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEG 437 KIGYW+E DK V T+ D S ++ +T +VTTILE PYVM+KKN EGN+RYEG Sbjct: 361 KIGYWSEVDKMVVTLTE----DDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEG 416 Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITL 497 YCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WNGMVGELVYG+AD+A+APLTITL Sbjct: 417 YCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITL 476 Query: 498 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 557 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSVVLFLV Sbjct: 477 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLV 536 Query: 558 SRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGG 617 SRFSPYEWH+EEFE+G + T NEFGIFNS WF+L F QQG DISPRSLS RIV G Sbjct: 537 SRFSPYEWHTEEFEDGEEST-----NEFGIFNSFWFALKLFFQQGADISPRSLSARIVAG 591 Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSK 677 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTL++GSTKEFFRRSK Sbjct: 592 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK 651 Query: 678 IAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 737 IAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV Sbjct: 652 IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 711 Query: 738 GGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDK 797 GGNLDSKGYGIATPKGS+L PVNLAVLKLSEQGVLDKLK+KWWYDKGECG+KDSGSK+K Sbjct: 712 GGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEK 771 Query: 798 TSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842 TSALSLSNVAGVFYIL+GGLGLAMLVALIEF YKSR+E+KRMKG Sbjct: 772 TSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMKGL 816 >5KUF-A nrPDB Length = 877 Score = 983 bits (2541), Expect = 0.0, Method: Composition-based stats. Identities = 347/844 (41%), Positives = 511/844 (60%), Gaps = 42/844 (4%) Query: 23 NNIQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTY 72 + ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASK 62 Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE- 128 + C Q S GV AIFG + N + S C AL V I + D + F + L P+ Sbjct: 63 KACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDF 122 Query: 129 --LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYR 186 L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + Sbjct: 123 SSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKD-AK 181 Query: 187 MLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKES 246 L +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ S Sbjct: 182 PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS 241 Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAE 302 G N+TGF+++N +T + I+++W + + D +AL YD V V++ Sbjct: 242 GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV 301 Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRR 361 A Q + + ++ C N PW G +++ +EGLTG + FN+ G R Sbjct: 302 AVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLR 353 Query: 362 TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDA-QAGGDNSSVQNRTYIVTTILEDPYV 420 T++ L VI +K +G+ KIG W+ + + S+ NR+ IVTTILE+PYV Sbjct: 354 TDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYV 413 Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480 + KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNGMV E Sbjct: 414 LFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRE 473 Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540 L+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ +IW Sbjct: 474 LIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIW 533 Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600 M ++ AY+GVSVVLF+++RFSPYEW++ + + N F + NS WF +GA MQ Sbjct: 534 MYVLLAYLGVSVVLFVIARFSPYEWYNP---HPCNPDSDVVENNFTLLNSFWFGVGALMQ 590 Query: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660 QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQT+I Sbjct: 591 QGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIE 650 Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720 YG +E GST FF++SKI+ ++KMW +M S SV V+++EEG+ RV S YA L+ES Sbjct: 651 YGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYALLMES 708 Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780 T E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L +K KW Sbjct: 709 TTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKW 767 Query: 781 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840 W G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ ++ K Sbjct: 768 WRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEK 823 Query: 841 -GFC 843 FC Sbjct: 824 RSFC 827 >5IPR-B nrPDB Length = 825 Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats. Identities = 185/834 (22%), Positives = 360/834 (43%), Gaps = 125/834 (14%) Query: 55 LLPQIDIVNI--SDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112 + P++++V + SD + R C S F + + + V +TP Sbjct: 59 VTPRVELVTMQESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPI 118 Query: 113 FPVDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQ 159 + + ++ Q P +++ +++I++ Y W F + G + Sbjct: 119 LGIHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFE 178 Query: 160 RVLDTAAEKN---WQVTAVNILTTTEEGYRMLFQ-DLEKKKERLVVVDCESERLNAILGQ 215 + + E + W++ V L + + Q L+K + ++++ C E I Sbjct: 179 NKVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEV 238 Query: 216 IVKLEKNGIGYHYILANLGFMDID--LNKFKESGANVTGFQLVNYTDTIPARIMQQWRTS 273 + G G+ +I+ +L D D ++F TG V+Y +W Sbjct: 239 AHSVGLTGYGFTWIVPSLVAGDTDTVPDEFP------TGLISVSYD---------EW--- 280 Query: 274 DARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQ 333 D+ P A DG+ ++ A ++ + I + ++ + + V + Sbjct: 281 --------DYDLP----ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YE 326 Query: 334 GIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFVPAA 392 ++R L V FEG ++ F+E G + + L +I + ++G + + + Sbjct: 327 AHMLKRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPV 384 Query: 393 TDAQAGGDNSSVQNRTYIVTTILEDPYVML---------------------KKNANQFEG 431 D + + + T+ E P+V++ + EG Sbjct: 385 FDLYPNSEEHKDE--HLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEG 442 Query: 432 ND----RYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487 + +G+C+++ +IAK V ++Y L +V++GK+G + WNGM+GE+V RA Sbjct: 443 GNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAY 500 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFA 546 +AV LTI R EV+DFS PF+ GIS+M+ + + +FL+P + ++W M V Sbjct: 501 MAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVML 559 Query: 547 YIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI- 605 I +V +F+ FSP ++ F I ++W G + Sbjct: 560 LIVSAVAVFVFEYFSPVGYN---------------GPSFTIGKAIWLLWGLVFNNSLPVQ 604 Query: 606 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------I 659 +P+ + +I+ VW FF +I ++SYTANLAAF+ R V + D Q Sbjct: 605 NPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAF 664 Query: 660 AYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLE 719 +GT+ GST+ R + + +M +YM R+ ++ ++ ++ K A++ + Sbjct: 665 RFGTVPNGSTERNIRNN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYD 715 Query: 720 STMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776 + + Y+ R + C + +G + GYGIA K S + V+LA+L+L G +++L Sbjct: 716 AAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEEL 775 Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830 ++ W G C + ++ +S L + N+AGVFY+L + L+++ ++E + Sbjct: 776 EALWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825 >5UOW-A nrPDB Length = 814 Score = 742 bits (1916), Expect = 0.0, Method: Composition-based stats. Identities = 213/877 (24%), Positives = 396/877 (45%), Gaps = 131/877 (14%) Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 77 P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C Sbjct: 2 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 59 Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125 S VYAI + + LT S+ + V +T + + F+ + Sbjct: 60 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 119 Query: 126 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 183 P +AL+ ++ + W + I D Q+ L+T E+ + + + + E Sbjct: 120 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 177 Query: 184 GYRMLFQ---DLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 240 G + L + ++ + R++++ + A+ L+ G GY +++ G +I Sbjct: 178 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 234 Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVM 300 + + + + G QL+N K SA D V V+ Sbjct: 235 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 266 Query: 301 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 358 A+A L ++I RG C+ N + W G +R L ++ +G+TG ++FNE Sbjct: 267 AQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNED 321 Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 411 G R ++ +++ + ++G ++ D K + P + G S + + + Sbjct: 322 GDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 378 Query: 412 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 442 TI ++P+V ++ + + Y G+CV+L Sbjct: 379 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDL 438 Query: 443 AAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPLTITLV 498 ++A+ + ++Y + +V+DGK+G + + + AWNGM+GEL+ G+AD+ VAPLTI Sbjct: 439 LIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNE 498 Query: 499 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 558 R + I+FSKPF G++I++KK + + SF+ P +W+ + + V+V+L+L+ Sbjct: 499 RAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 557 Query: 559 RFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGG 617 RFSP+ + + + + + + +++WFS + G + +PRS S RI+G Sbjct: 558 RFSPFG-------RFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGM 610 Query: 618 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFR 674 VW F +II++SYTANLAAFL + R I D + + Y T++ S +FR Sbjct: 611 VWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFR 670 Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDT 734 R M+ +M+ + E + VR +K +A++ +S + E+ E + CD Sbjct: 671 RQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQDCDL 722 Query: 735 MKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGS 794 + G G+GI K S + V+L +LK E G +++L K W EC S+ + Sbjct: 723 VTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRSNAP 781 Query: 795 KDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYK 831 + L+ N+AGVFY++ GG+ + + IE YK Sbjct: 782 ----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >6IRA-D nrPDB Length = 853 Score = 740 bits (1910), Expect = 0.0, Method: Composition-based stats. Identities = 193/838 (23%), Positives = 350/838 (41%), Gaps = 114/838 (13%) Query: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120 ++N +D + C S F + + + P + Sbjct: 73 LMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSHTFVPILGIHGGAS 132 Query: 121 FVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAE 167 ++ Q +Q+ ++ I+ Y W F + G + T + Sbjct: 133 MIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVD 192 Query: 168 KN---WQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGI 224 + W + V L T+ E + Q L+K ++++ C + IL + L G Sbjct: 193 NSFVGWDMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGY 251 Query: 225 GYHYILANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVD 282 + +I+ +L G ++ +F +G V+Y D W S Sbjct: 252 DFFWIVPSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------- 287 Query: 283 WKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQ 342 A DG+ ++ A S+ + I + C P + + Sbjct: 288 ------LEARVRDGIGILTTAASSMLEKFSYIPEAKAS--CYGQMERPEVPMHTLHPFMV 339 Query: 343 QVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHD-GIRKIGYWNEDDKFVPAAT--DAQAGG 399 V ++G ++ F E+G + + L VI + D K+G W + A ++ Sbjct: 340 NVTWDG--KDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFS 397 Query: 400 DNSSVQNRTYIVTTILEDPYV---------------------MLKKNANQFEG---NDRY 435 D N + T+ E P+V +K N + EG Sbjct: 398 DCEPDDNH-LSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCC 456 Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 +G+C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTI 514 Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 554 R EV+DFS PF+ GIS+M+ + + +FL+P + +W M V I ++ + Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSRSNGTVSPS-AFLEPFSASVWVMMFVMLLIVSAIAV 573 Query: 555 FLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGR 613 F+ FSP + + +G+ F I ++W G + +P+ + + Sbjct: 574 FVFEYFSPVGY-NRNLAKGKAP----HGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSK 628 Query: 614 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAG 667 I+ VW FF +I ++SYTANLAAF+ R V + D Q +GT+ G Sbjct: 629 IMVSVWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNG 688 Query: 668 STKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIE 727 ST+ R + + M YM + E+ ++ ++ K A++ ++ + Y Sbjct: 689 STERNIRNN----YPYMHQYMTKFNQ----KGVEDALVSLKTGKLD-AFIYDAAVLNYKA 739 Query: 728 QR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784 R + C + +G + GYGIA KGS + ++LA+L+ G +++L++ W Sbjct: 740 GRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--T 797 Query: 785 GECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF-CYKSRSESKRMKG 841 G C + ++ +S L + N+AGVFY+L + L+++ + E YKSR+E+KRMKG Sbjct: 798 GIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMKG 853 >4PE5-B nrPDB Length = 820 Score = 730 bits (1883), Expect = 0.0, Method: Composition-based stats. Identities = 186/832 (22%), Positives = 352/832 (42%), Gaps = 115/832 (13%) Query: 55 LLPQIDIVNIS--DSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPS 112 ++P++++V ++ D + R C S F + + + +TP Sbjct: 38 VVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPI 97 Query: 113 FPVDTSNQFVL----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQ 159 + + ++ Q P +++ +++I++ Y W F + G Sbjct: 98 LGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFV 157 Query: 160 RVLDTAAEKN---WQVTAVNILTTT-EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQ 215 + + E + W++ V +L + ++G + L+K + ++++ C E I Sbjct: 158 NKIRSTIENSFVGWELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEV 217 Query: 216 IVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDA 275 + G GY +I+ +L D D + TG V+Y +W Sbjct: 218 ANSVGLTGYGYTWIVPSLVAGDTDTVPSEFP----TGLISVSYD---------EW----- 259 Query: 276 RDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGI 335 D+ P A DG+ ++ A + + I ++ C Q Sbjct: 260 ------DYGLP----ARVRDGIAIITTAASDMLSEHSFIPEPKSS--CYNTHEKRIYQSN 307 Query: 336 DIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFVPAATD 394 + R L V FEG ++ F+E G + + L +I + ++G W + + Sbjct: 308 MLNRYLINVTFEG--RDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVW 365 Query: 395 AQAGGDNSSVQNRTYIVTTILEDPYVML-------------------------KKNANQF 429 + D+ + T+ E P+V++ K + Sbjct: 366 PRMTQDD------HLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPG 419 Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 +G+C+++ +I+K V ++Y L +V++GK+G + WNGM+GE+V RA +A Sbjct: 420 YIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKI--NGTWNGMIGEVVMKRAYMA 477 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYI 548 V LTI R EV+DFS PF+ GIS+M+ + + +FL+P + +W M V I Sbjct: 478 VGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSACVWVMMFVMLLI 536 Query: 549 GVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SP 607 +V +F+ FSP + + +GR+ F I ++W G + +P Sbjct: 537 VSAVAVFVFEYFSPVGY-NRSLADGREPG----GPSFTIGKAIWLLWGLVFNNSVPVQNP 591 Query: 608 RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAY 661 + + +I+ VW FF +I ++SYTANLAAF+ E V + D Q + Sbjct: 592 KGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRF 651 Query: 662 GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLEST 721 GT+ GST+ R + + +M YM R ++ ++ ++ K A++ ++ Sbjct: 652 GTVPNGSTERNIRNN----YAEMHAYMGKFNQ----RGVDDALLSLKTGKLD-AFIYDAA 702 Query: 722 MNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKS 778 + Y+ R + C + +G S GYGIA K S + V+LA+L+L G +++L++ Sbjct: 703 VLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEA 762 Query: 779 KWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830 W G C + ++ +S L N+AGVFY+L + L+++ + E + Sbjct: 763 LWL--TGIC--HNEKNEVMSSQLDCDNMAGVFYMLGAAMALSLITFISEHLF 810 >5FXI-A nrPDB Length = 846 Score = 727 bits (1877), Expect = 0.0, Method: Composition-based stats. Identities = 211/903 (23%), Positives = 390/903 (43%), Gaps = 150/903 (16%) Query: 22 PNNIQIGGLFPNQQSQEHAAFRFALSQLTEP----PKLLPQIDIVNISDSFEMTYRFCSQ 77 P + IG + ++ ++ FR A++Q + L + + ++ +M C Sbjct: 2 PKIVNIGAVLSTRKHEQ--MFREAVNQANKRHGSWKIQLQATSVTHKPNAIQMALSVCED 59 Query: 78 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 125 S VYAI + + T S+ + V +T + + F+ + Sbjct: 60 LISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTV 119 Query: 126 RPELQE--ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEK--------------- 168 P + ++ Y W + + D Q+ L+T E+ Sbjct: 120 PPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKSKKRNYENLDQ 179 Query: 169 ----NWQVTAVNILTTTEEGYRM---LFQDLEKKKERLVVVDCESERLNAILGQIVKLEK 221 N + + + G + L + + + R++++ + + L+ Sbjct: 180 LSYDNKRGPKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDM 239 Query: 222 NGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRV 281 G GY +++ G +I N + + + G QL+N Sbjct: 240 TGSGYVWLV---GEREISGNALRYAPDGIIGLQLIN------------------------ 272 Query: 282 DWKRPKYTSALTYDGVKVMAEAFQSLRR-QRIDISRRGNAGDCLANPAVPWGQGIDIQRA 340 K SA D V V+A+A L + I RG C+ N + W G +R Sbjct: 273 ----GKNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRV 323 Query: 341 LQQVRF-EGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAA 392 L ++ +G+TG V+FNE G R ++ +++ + ++G +N D K + P Sbjct: 324 LMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGG 383 Query: 393 TDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYE---------------- 436 + G S + + + TI ++P+V +K + + + Sbjct: 384 ETEKPRGYQMSTRLK---IVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPND 440 Query: 437 ---------------GYCVELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGM 477 G+C++L ++A+ + ++Y + +V+DGK+G + + + K WNGM Sbjct: 441 TSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGM 500 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537 +GEL+ G+AD+ VAPLTI R + I+FSKPF G++I++KK + + SF+ P Sbjct: 501 MGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQS 559 Query: 538 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGA 597 +W+ + + V+V+L+L+ RFSP+ + + S+ ++ + +++WFS G Sbjct: 560 TLWLLVGLSVHVVAVMLYLLDRFSPFG-------RFKVNSQSESTDALTLSSAMWFSWGV 612 Query: 598 FMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656 + G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + Sbjct: 613 LLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLR 672 Query: 657 T---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGK 713 + Y T++ S +FRR M+ +M+ + E + VR +K Sbjct: 673 NPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL- 725 Query: 714 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVL 773 +A++ +S + E+ E + CD + G G+GI K S + V+L++LK E G + Sbjct: 726 HAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFM 784 Query: 774 DKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSR 833 + L K W EC S+ + + L+ N+AGVF ++ GG+ + + IE YK Sbjct: 785 EDL-DKTWVRYQECDSRSNAP----ATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRH 839 Query: 834 SES 836 ++ Sbjct: 840 KDA 842 >5UP2-B nrPDB Length = 831 Score = 725 bits (1870), Expect = 0.0, Method: Composition-based stats. Identities = 183/879 (20%), Positives = 354/879 (40%), Gaps = 109/879 (12%) Query: 4 IFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFA-LSQLTEPPKLLPQIDIV 62 ++ F G LG +FP + I + + R ++ + +V Sbjct: 8 LYTFLYAGDLGHGAEKSFP-VLNIAVILGRTRYITERDIRSLWTRDMSLDFDVNVVTLLV 66 Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122 +D + C S F + + + P + + + Sbjct: 67 QQTDPKSIITHVCDLMSGTKIHGVVFGDDTDQEAIAQILDFVSSQTFIPILGIHGGSSMI 126 Query: 123 L----------QLRPELQE---ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKN 169 + Q +++ +++I++ Y W F I G + T + + Sbjct: 127 MADKDEMSTFFQFGASIKQQATVMLNIMEEYDWHVFSVITSNFPGYRDFISFIKTTVDNS 186 Query: 170 ---WQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGY 226 W+V L T+ + L Q L+K ++++ C + I + L G G+ Sbjct: 187 FVGWEVQNYITLDTSYTDAQTLTQ-LKKIHSSVILLYCSKDEATYIFEEARSLGLMGYGF 245 Query: 227 HYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRP 286 +I+ +L + D+ ++ +G V+Y DW Sbjct: 246 VWIVPSLVTGNTDIIPYEFP----SGLVSVSYD----------------------DWDYG 279 Query: 287 KYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF 346 A DG+ ++ A ++ + I + C + + V + Sbjct: 280 --IEARVRDGLGIITTAASAMLEKHSVIPEAKTS--CYGQNERNDPPLHTLHNFMINVTW 335 Query: 347 EGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYW-----------------NEDDKF 388 +G ++ F E G + N L V+ + K+G W + DD Sbjct: 336 DG--KDLSFTEDGYQANPKLVVLLLNMEREWEKVGKWEAKSLNMKYPVWPRIDSDHDDNH 393 Query: 389 VPAATDAQAGGDNSSVQNRTYIVTTILEDP-----YVMLKKNANQFEG-NDRYEGYCVEL 442 + T +A V+N Y+ T + + Y L + + +G+C+++ Sbjct: 394 LSIVTLEEA--PFVIVENIDYLTGTCVRNTVPCRKYFRLANSTTEGTSVKKCCKGFCIDI 451 Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502 +++K V ++Y L +V++GK+G + + WNGM+GE+VY RA +AV LTI R Sbjct: 452 LKKLSKTVKFTYDLYLVTNGKHGKKIKN--VWNGMIGEVVYKRAVMAVGSLTINEERSVA 509 Query: 503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 561 +DFS PF+ GIS+M+ + + +FL+P + +W M V + ++ +F+ FS Sbjct: 510 VDFSVPFVETGISVMVSRSAGTVSPS-AFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFS 568 Query: 562 PYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 620 P + + +G+D F I ++W G + +P+ + +I+ +W Sbjct: 569 PVGY-NRNLAQGKDP----HGPSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWA 623 Query: 621 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFR 674 FF +I ++SYTANLAAF+ R V + D Q +GT+ GST+ R Sbjct: 624 FFAVIFLASYTANLAAFMIQRRFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIR 683 Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCD 733 + + M YM + ++ ++ ++ K A++ ++ + Y+ R + C Sbjct: 684 NN----YPDMHQYMVKFHQ----KGVQDALVSLKTGKLD-AFIYDAAVLNYMAGRDEGCK 734 Query: 734 TMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791 + +G + GYGIA KGS + P++LA+L+ G +++L+ W G C Sbjct: 735 LVTIGSGYIFATTGYGIALQKGSRWKRPIDLALLQFVGDGEMEELEKLWL--TGIC--HT 790 Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830 ++ +S L + N+AGVFY+L + L+++ + E + Sbjct: 791 EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHLF 829 >5KUH-A nrPDB Length = 757 Score = 612 bits (1579), Expect = e-175, Method: Composition-based stats. Identities = 197/601 (32%), Positives = 309/601 (51%), Gaps = 37/601 (6%) Query: 23 NNIQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTY 72 + ++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASK 62 Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE- 128 + C Q S GV AIFG + N + S C AL V I + D + F + L P+ Sbjct: 63 KACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDF 122 Query: 129 --LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYR 186 L A++ ++ +KW+T +YD GL LQ ++ + N ++ + T++ + Sbjct: 123 SSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKD-AK 181 Query: 187 MLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKES 246 L +++++ KE V+ DC E IL Q + + YHYI L +D+ ++ S Sbjct: 182 PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS 241 Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR----PKYTSALTYDGVKVMAE 302 G N+TGF+++N +T + I+++W + + D +AL YD V V++ Sbjct: 242 GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV 301 Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRR 361 A Q + + ++ C N PW G +++ +EGLTG + FN+ G R Sbjct: 302 AVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLR 353 Query: 362 TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDA-QAGGDNSSVQNRTYIVTTILEDPYV 420 T++ L VI +K +G+ KIG W+ + + S+ NR+ IVTTILE+PYV Sbjct: 354 TDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYV 413 Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480 + KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNGMV E Sbjct: 414 LFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRE 473 Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540 L+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K D LA + Sbjct: 474 LIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKG-----TPIDSADDLAKQTK 528 Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600 + G ++ F S+ S Y+ F R Q+ +S+E GI L M+ Sbjct: 529 IEYGAVEDGSTMTFFKKSKISTYD-KMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLME 587 Query: 601 Q 601 Sbjct: 588 S 588 Score = 273 bits (699), Expect = 2e-73, Method: Composition-based stats. Identities = 96/220 (43%), Positives = 142/220 (64%), Gaps = 12/220 (5%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PI+SA+DLAKQT+I YG +E GST FF++SKI+ ++KMW +M S SV V+ Sbjct: 509 ILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVK 568 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 ++EEG+ RV S YA L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R Sbjct: 569 SSEEGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 625 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLG 818 + +A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL Sbjct: 626 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLV 681 Query: 819 LAMLVALIEFCYKSRSESKRMK-GFCLIPQQSINEAIRTS 857 L++ VA+ EF YKS+ ++ K FC ++ E +R S Sbjct: 682 LSVFVAVGEFLYKSKKNAQLEKRSFC----SAMVEELRMS 717 >5L2E-A nrPDB Length = 688 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 126/581 (21%), Positives = 255/581 (43%), Gaps = 54/581 (9%) Query: 23 NNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCS 76 + I IG +F ++ FR A+ L + ++L + V+ ++ F+ C Sbjct: 4 SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACE 63 Query: 77 QFSKGVYAIFGFYERRTVNMLTSFCGALHVCFI--------TPSFP-----VDTSNQFVL 123 ++G+ A+ + L S A+H+ + TP + ++ + L Sbjct: 64 LMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTL 123 Query: 124 QLRPE--LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTT 181 +RP L E ++ ++ Y WQ F+ YD++ + +Q LD +++ V + Sbjct: 124 SVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNI 183 Query: 182 EEGYRMLF-----QDLEKKKE--RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLG 234 + LF ++L + ++ R ++ + + ++V+ H+I+ N Sbjct: 184 NKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEE 243 Query: 235 FMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQ-WRTSDARDHTRVDWKRP-----KY 288 D+D+ + ++ ++ T +P I Q+ +R + T D K P + Sbjct: 244 INDVDVQELVRR--SIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEI 301 Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEG 348 ++ YD V ++A AF + R S + C+ + PW G + +++ G Sbjct: 302 SNLYIYDTVLLLANAFHKKLQDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGVNG 359 Query: 349 LTGNVQFNEKGRRTNYTLHVIEMKH-----DGIRKIGYWNEDDKFVPAATDAQAGGDNSS 403 LTG+++F E G N ++ + G+RK+G WN + TD + + Sbjct: 360 LTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRG 419 Query: 404 VQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGK 463 V R V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D K Sbjct: 420 VVLR---VVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHK 474 Query: 464 YGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 523 YG+ D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++ Sbjct: 475 YGSPQED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRG-- 531 Query: 524 SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564 L L+ + + + +P+E Sbjct: 532 ---TSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFE 569 Score = 176 bits (447), Expect = 3e-44, Method: Composition-based stats. Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 10/158 (6%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAE 692 + R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + Sbjct: 526 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 585 Query: 693 PSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIAT 750 S V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA Sbjct: 586 GSENNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 643 Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 GS R + +L+L + G +D LK KWW G+C Sbjct: 644 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 681 >5UN1-G nrPDB Length = 451 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 144/476 (30%), Positives = 243/476 (51%), Gaps = 66/476 (13%) Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYC 439 + TI ++P+V ++ + + Y G+C Sbjct: 5 LKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFC 64 Query: 440 VELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPLTI 495 V+L ++A+ + ++Y + +V+DGK+G + + + AWNGM+GEL+ G+AD+ VAPLTI Sbjct: 65 VDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTI 124 Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555 R + I+FSKPF G++I++KK + + SF+ P +W+ + + V+V+L+ Sbjct: 125 NNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLY 183 Query: 556 LVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRI 614 L+ RFSP+ GR + + + +++WFS + G + +PRS S RI Sbjct: 184 LLDRFSPF---------GRFE------DALTLSSAMWFSWRVLLNSGLGEGAPRSFSARI 228 Query: 615 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKE 671 +G VW F +II++SYTANLAAFL + R I D + + Y T++ S Sbjct: 229 LGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDI 288 Query: 672 FFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP 731 +FRR M+ +M+ + E + VR +K +A++ +S + E+ E + Sbjct: 289 YFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQK 340 Query: 732 CDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791 CD + G G+GI K S + V+L +LK E G +++L K W EC S+ Sbjct: 341 CDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRS 399 Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847 + + L+ N+AGVF ++ GG+ + + IE YKSR+E+KRMKG ++ Q Sbjct: 400 NAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLFQ 451 >5UN1-B nrPDB Length = 448 Score = 485 bits (1249), Expect = e-137, Method: Composition-based stats. Identities = 135/477 (28%), Positives = 237/477 (49%), Gaps = 68/477 (14%) Query: 408 TYIVTTILEDPYVML---------------------KKNANQFEGND----RYEGYCVEL 442 + T+ E P+V++ + EG + +G+C+++ Sbjct: 3 HLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDI 62 Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502 +IAK V ++Y L +V++GK+G + WNGM+GE+V RA +AV LTI R EV Sbjct: 63 LKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTINEERSEV 120 Query: 503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 561 +DFS PF+ GIS+M+ + + +FL+P + ++W M V I +V +F+ FS Sbjct: 121 VDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFS 179 Query: 562 PYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 620 P ++ F I ++W G + +P+ + +I+ VW Sbjct: 180 PVGYN---------------GPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWA 224 Query: 621 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------IAYGTLEAGSTKEFFR 674 FF +I ++SYTANLAAF+ R V + D Q +GT+ GST+ R Sbjct: 225 FFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIR 284 Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCD 733 + + +M +YM R+ ++ ++ ++ K A++ ++ + Y+ R + C Sbjct: 285 NN----YLEMHSYMVKFNQ----RSVQDALLSLKSGKLD-AFIYDAAVLNYMAGRDEGCK 335 Query: 734 TMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791 + +G + GYGIA K S + V+LA+L+L G +++L++ W G C + Sbjct: 336 LVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HN 391 Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF-CYKSRSESKRMKGFCLIPQ 847 ++ +S L + N+AGVFY+L + L+++ ++E YKSR+E+KRMKG ++ Q Sbjct: 392 EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGLEVLFQ 448 >1YAE-A nrPDB Length = 312 Score = 244 bits (622), Expect = 2e-64, Method: Composition-based stats. Identities = 95/226 (42%), Positives = 129/226 (57%), Gaps = 21/226 (9%) Query: 396 QAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYR 455 + S+ NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y Sbjct: 2 KPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYE 61 Query: 456 LEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515 + +V DGKYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGIS Sbjct: 62 IRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGIS 121 Query: 516 IMIKKPQKSKPGVFSFL--------------------DPLAYEIWMCIVFAYIGVSVVLF 555 I+ +KP + PGVFSFL D LA + + G ++ F Sbjct: 122 ILYRKPNGTNPGVFSFLNGGSLVPRGSERMESPIDSADDLAKQTKIEYGAVEDGATMTFF 181 Query: 556 LVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQ 601 S+ S Y+ F R Q+ +SNE GI L M+ Sbjct: 182 KKSKISTYD-KMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMES 226 Score = 225 bits (573), Expect = 6e-59, Method: Composition-based stats. Identities = 79/165 (47%), Positives = 112/165 (67%), Gaps = 7/165 (4%) Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT 700 ERM SPI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208 Query: 701 EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPV 760 EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265 Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSN 805 +A+L+L E+G L +K KWW G C ++S + SAL + N Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQN 306 >2XXT-A nrPDB Length = 261 Score = 228 bits (581), Expect = 8e-60, Method: Composition-based stats. Identities = 86/197 (43%), Positives = 117/197 (59%), Gaps = 6/197 (3%) Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464 NR+ IVTTILE+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKY Sbjct: 2 SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKY 61 Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524 GA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 62 GAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKG--- 118 Query: 525 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNE 584 D LA + + G ++ F S+ S Y+ F R Q+ +SNE Sbjct: 119 --TPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYD-KMWAFMSSRRQSVLVKSNE 175 Query: 585 FGIFNSLWFSLGAFMQQ 601 GI L M+ Sbjct: 176 EGIQRVLTSDYAFLMES 192 Score = 217 bits (552), Expect = 2e-56, Method: Composition-based stats. Identities = 71/151 (47%), Positives = 102/151 (67%), Gaps = 4/151 (2%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PI+SA+DLAKQT+I YG +E G+T FF++SKI+ ++KMW +M S SV V+ Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 172 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 + EEG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R Sbjct: 173 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 229 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789 + +A+L+L E+G L +K KWW G C Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPE 259 >3FAT-A nrPDB Length = 260 Score = 228 bits (581), Expect = 9e-60, Method: Composition-based stats. Identities = 128/147 (87%), Positives = 140/147 (95%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 + +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT Sbjct: 114 KKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTA 173 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+LR PVN Sbjct: 174 EGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVN 233 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGECG 788 LAVLKLSE GVLDKLK+KWWYDKGECG Sbjct: 234 LAVLKLSEAGVLDKLKNKWWYDKGECG 260 Score = 196 bits (497), Expect = 4e-50, Method: Composition-based stats. Identities = 98/184 (53%), Positives = 122/184 (66%), Gaps = 6/184 (3%) Query: 407 RTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 RT +VTTI+E PYVM KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGA Sbjct: 2 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 61 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526 RD DTK WNGMVGELVYG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKK Sbjct: 62 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKG----- 116 Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFG 586 + LA + + G + F S+ + YE + + + ++ G Sbjct: 117 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYE-KMWTYMRSAEPSVFTRTTAEG 175 Query: 587 IFNS 590 + Sbjct: 176 VARV 179 >5O9A-A nrPDB Length = 264 Score = 228 bits (580), Expect = 1e-59, Method: Composition-based stats. Identities = 130/151 (86%), Positives = 142/151 (94%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + + +PIESAEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVR Sbjct: 113 IMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 172 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 TT EG+ RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+L Sbjct: 173 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGN 232 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789 VNLAVLKLSEQG+LDKLK+KWWYDKGECGS Sbjct: 233 AVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 263 Score = 202 bits (513), Expect = 6e-52, Method: Composition-based stats. Identities = 97/186 (52%), Positives = 122/186 (65%), Gaps = 6/186 (3%) Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464 N+T +VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKY Sbjct: 2 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 61 Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524 GARD DTK WNGMVGELVYG+AD+A+APLTIT VREEVIDFSKPFMSLGISIMIKK Sbjct: 62 GARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKG--- 118 Query: 525 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNE 584 + L+ + + G + F S+ + ++ + + + ++ Sbjct: 119 --TPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFD-KMWTYMRSAEPSVFVRTTA 175 Query: 585 FGIFNS 590 G+ Sbjct: 176 EGVARV 181 >3DP4-A nrPDB Length = 278 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 126/150 (84%), Positives = 141/150 (94%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + + +PIESAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF + Sbjct: 129 IMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 188 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 TT +G+ RVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL Sbjct: 189 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGT 248 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 PVNLAVLKLSEQG+LDKLK+KWWYDKGECG Sbjct: 249 PVNLAVLKLSEQGILDKLKNKWWYDKGECG 278 Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats. Identities = 108/203 (53%), Positives = 129/203 (63%), Gaps = 6/203 (2%) Query: 388 FVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIA 447 VP + D+S NRT +VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIA Sbjct: 1 LVPRGSAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIA 60 Query: 448 KHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSK 507 KHV Y+L IV DGKYGARDP+TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSK Sbjct: 61 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 120 Query: 508 PFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHS 567 PFMSLGISIMIKK + LA + + G + F S+ + YE Sbjct: 121 PFMSLGISIMIKKG-----TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYE-KM 174 Query: 568 EEFEEGRDQTTSDQSNEFGIFNS 590 + + + + ++ G+ Sbjct: 175 WSYMKSAEPSVFTKTTADGVARV 197 >4MF3-A nrPDB Length = 261 Score = 225 bits (573), Expect = 6e-59, Method: Composition-based stats. Identities = 89/199 (44%), Positives = 121/199 (60%), Gaps = 7/199 (3%) Query: 403 SVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462 S+ NRT IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y +++V DG Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60 Query: 463 KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 522 KYGA++ D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 61 KYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKG- 118 Query: 523 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQS 582 D LA + + G ++ F S+ S YE F R QT ++ Sbjct: 119 ----TPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYE-KMWAFMSSRQQTALVRN 173 Query: 583 NEFGIFNSLWFSLGAFMQQ 601 ++ GI L M+ Sbjct: 174 SDEGIQRVLTTDYALLMES 192 Score = 214 bits (545), Expect = 1e-55, Method: Composition-based stats. Identities = 70/152 (46%), Positives = 101/152 (66%), Gaps = 4/152 (2%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PI+SA+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + + VR Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVR 172 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 ++EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R Sbjct: 173 NSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRD 229 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790 + +A+L+L E+G L +K KWW G C + Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEE 260 >4IGR-A nrPDB Length = 258 Score = 216 bits (551), Expect = 3e-56, Method: Composition-based stats. Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 8/196 (4%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 NR+ IVTT+LE+P+VM +K+ GNDR+EGYC++L E+A +G+SY + +V DGKYG Sbjct: 5 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYG 64 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525 A+D D WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K Sbjct: 65 AQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKG---- 119 Query: 526 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585 D LA + + G ++ F S+ S +E F + + ++NE Sbjct: 120 -TPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFE-KMWAFMSSK-PSALVKNNEE 176 Query: 586 GIFNSLWFSLGAFMQQ 601 GI +L M+ Sbjct: 177 GIQRTLTADYALLMES 192 Score = 205 bits (521), Expect = 8e-53, Method: Composition-based stats. Identities = 72/150 (48%), Positives = 100/150 (66%), Gaps = 5/150 (3%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ FEKMW +M S++PS V+ Sbjct: 114 ILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVK 172 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 EEG+ R + YA L+EST EYI QR C+ ++GG +DSKGYGI TP GS R Sbjct: 173 NNEEGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRD 229 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 + +A+L+L E+ L +K KWW G C Sbjct: 230 KITIAILQLQEEDKLHIMKEKWWRGSG-CP 258 >5IKB-A nrPDB Length = 257 Score = 205 bits (522), Expect = 6e-53, Method: Composition-based stats. Identities = 79/198 (39%), Positives = 116/198 (58%), Gaps = 7/198 (3%) Query: 406 NRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYG 465 N T +VTTILE+PY+MLK N EGNDRYEG+CV++ E+A+ + ++Y++ +V DG YG Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62 Query: 466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 525 + + W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K Sbjct: 63 VPEAN-GTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKG---- 117 Query: 526 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585 +D LA + + + G S+ F SR+ Y+ + + + +S E Sbjct: 118 -TPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQ-RMWNYMYSKQPSVFVKSTEE 175 Query: 586 GIFNSLWFSLGAFMQQGC 603 GI L + ++ Sbjct: 176 GIARVLNSNYAFLLESTM 193 Score = 202 bits (514), Expect = 4e-52, Method: Composition-based stats. Identities = 76/150 (50%), Positives = 101/150 (67%), Gaps = 4/150 (2%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PIES +DLA QT I YGT+ GS+ FF+ S+ +++MW YM S +PSVFV+ Sbjct: 112 ILYRKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVK 171 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 +TEEG+ RV S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R Sbjct: 172 STEEGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRD 228 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 +LA+L+L E L+ LK KWW + G+C Sbjct: 229 EFDLAILQLQENNRLEILKRKWW-EGGKCP 257 >5EHM-A nrPDB Length = 268 Score = 205 bits (520), Expect = 1e-52, Method: Composition-based stats. Identities = 81/152 (53%), Positives = 106/152 (69%), Gaps = 4/152 (2%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + R +PIESAEDLAKQT I YG L+ GST FFR SKI+ +++MW++M+SA PSVF Sbjct: 117 ILYRKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTA 176 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 + EG+ RV K KG YA+L+EST EY+ +R C+ +VGG LD+K YGIATP S R Sbjct: 177 SNGEGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRT 235 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDK---GEC 787 +N +LKL E+G L LK+KWW +K G+C Sbjct: 236 AINSVILKLQEEGKLHILKTKWWKEKRGGGKC 267 Score = 191 bits (485), Expect = 1e-48, Method: Composition-based stats. Identities = 70/190 (36%), Positives = 112/190 (58%), Gaps = 6/190 (3%) Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460 +++++N+T +VTTIL +PY M K++A GND++EGY V+L EI+K +G++Y++++V Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61 Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121 Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSD 580 + LA + + G + F S+ S Y+ F E + Sbjct: 122 G-----TPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQ-RMWSFMESARPSVFT 175 Query: 581 QSNEFGIFNS 590 SN G+ Sbjct: 176 ASNGEGVERV 185 >5DT6-A nrPDB Length = 267 Score = 197 bits (501), Expect = 2e-50, Method: Composition-based stats. Identities = 82/146 (56%), Positives = 105/146 (71%), Gaps = 1/146 (0%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 + +PI++ EDL QT++ YGTL GST EFFRRS+I + KMW YM A V T + Sbjct: 122 KKGTPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMN-ANQHHSVHTYD 180 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVN 761 EG+ RVR+SKGKYA L+ES NEY+ R PCDTMKVG N+D+KG+G+ATP GS LR +N Sbjct: 181 EGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLN 240 Query: 762 LAVLKLSEQGVLDKLKSKWWYDKGEC 787 AVL L E G L ++++KWW+DK EC Sbjct: 241 EAVLTLKENGELLRIRNKWWFDKTEC 266 Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats. Identities = 73/190 (38%), Positives = 103/190 (54%), Gaps = 10/190 (5%) Query: 404 VQNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461 +N TYIV+++LE+PY+ LK+ GNDR+EGYC +LA +A +G Y + +V D Sbjct: 4 DRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQD 63 Query: 462 GKYGARDPDT-KAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 G YGA + W+GMVGEL+ AD+A++ +TIT RE VIDFSKPFM+LGISIMIKK Sbjct: 64 GNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKK 123 Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSD 580 K + L + + G + F S+ + E +Q S Sbjct: 124 GTPIKTP-----EDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNA--NQHHSV 176 Query: 581 QSNEFGIFNS 590 + + GI Sbjct: 177 HTYDEGIRRV 186 >5CC2-A nrPDB Length = 265 Score = 175 bits (444), Expect = 6e-44, Method: Composition-based stats. Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 10/158 (6%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKSAE 692 + R + I+S +DL+KQT+I YGT+ + + R + FE+ MW + + Sbjct: 109 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 168 Query: 693 PSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIAT 750 S V ++ G+ +V+ G YA++ ++ + EY+ P C VG + +GYGIA Sbjct: 169 GSENNVLESQAGIQKVKY--GNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 226 Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 GS R + +L+L + G +D LK KWW G+C Sbjct: 227 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 264 Score = 142 bits (357), Expect = 8e-34, Method: Composition-based stats. Identities = 42/156 (26%), Positives = 82/156 (52%), Gaps = 8/156 (5%) Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468 V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y + + D KYG+ Sbjct: 5 LRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQ 62 Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 528 D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +++++ Sbjct: 63 ED-GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRG-----TS 116 Query: 529 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 564 L L+ + + + +P+E Sbjct: 117 IQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFE 152 >4WXJ-A nrPDB Length = 269 Score = 173 bits (437), Expect = 4e-43, Method: Composition-based stats. Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 1/146 (0%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 + + I S DL Q ++ +GT+ G+T +F S W M S +P F + Sbjct: 120 ILSYKGTDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTK 179 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 EEG+ RV+ SKG YA+L+E+T +Y QR C+ ++G + K YGIA P + R Sbjct: 180 NNEEGVDRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRS 238 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDK 784 +++ +L+LSE+G L KL++KW+ Sbjct: 239 NLSVGILRLSERGELFKLRNKWFNSN 264 Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats. Identities = 53/184 (28%), Positives = 83/184 (45%), Gaps = 8/184 (4%) Query: 409 YIVTTILEDPYVMLKKNAN--QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 Y V T + PY ++ +EGN+R+EGY V+L +A+ + + E V D KYG+ Sbjct: 11 YTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGS 70 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526 D +T W+G++ +L+ A + + LTIT R V+DF+ PFM LGISI+ K Sbjct: 71 YDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKGTDIGS 130 Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFG 586 L L + + G + V F S + ++NE G Sbjct: 131 -----LHDLVDQNKVQFGTIRGGATSVYFSESN-DTDNRMAWNKMLSFKPDAFTKNNEEG 184 Query: 587 IFNS 590 + Sbjct: 185 VDRV 188 >5I2K-B nrPDB Length = 293 Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats. Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 12/154 (7%) Query: 639 TVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695 + + + I D + + Y T++ S +FRR M+ +M+ Sbjct: 149 ILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN--- 203 Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755 + E + VR +K +A++ +S + E+ E + CD + G G+GI K S Sbjct: 204 -YESAAEAIQAVRDNKL-HAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSP 260 Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789 + V+L++LK E G ++ L K W EC S Sbjct: 261 WKQNVSLSILKSHENGFMEDL-DKTWVRYQECDS 293 Score = 132 bits (333), Expect = 5e-31, Method: Composition-based stats. Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 43/211 (20%) Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYE-------------------------------G 437 + TI ++P+V +K + + + G Sbjct: 7 LKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYG 66 Query: 438 YCVELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPL 493 +C++L ++A+ + ++Y + +V+DGK+G + + + K WNGM+GEL+ G+AD+ VAPL Sbjct: 67 FCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPL 126 Query: 494 TITLVREEVIDFSKPFMSLGISIMIKKP------QKS--KPGVFSFLDPLAYEIWMCIVF 545 TI R + I+FSKPF G++I++KK + F+ + + I F Sbjct: 127 TINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYF 186 Query: 546 AYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQ 576 ++ YE +E + RD Sbjct: 187 RRQVELSTMYRHMEKHNYESAAEAIQAVRDN 217 >5H8N-A nrPDB Length = 285 Score = 157 bits (397), Expect = 2e-38, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 20/156 (12%) Query: 643 MVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVF 696 + + D Q +GT+ GST+ R + + M YM Sbjct: 141 RGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYMTKFNQ--- 193 Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKG 753 + E+ ++ ++ K A++ ++ + Y R + C + +G + GYGIA KG Sbjct: 194 -KGVEDALVSLKTGKLD-AFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKG 251 Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789 S + ++LA+L+ G +++L++ W G C + Sbjct: 252 SPWKRQIDLALLQFVGDGEMEELETLWL--TGICHN 285 Score = 133 bits (335), Expect = 3e-31, Method: Composition-based stats. Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 27/174 (15%) Query: 403 SVQNRTYIVTTILEDPYV---------------------MLKKNANQFEG---NDRYEGY 438 S + + T+ E P+V +K N + EG +G+ Sbjct: 2 SPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGF 61 Query: 439 CVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLV 498 C+++ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI Sbjct: 62 CIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTINEE 119 Query: 499 REEVIDFSKPFMSLGISIMIKKP-QKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551 R EV+DFS PF+ GIS+M+ + Q + F P Y G + Sbjct: 120 RSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGST 173 >4YKP-A nrPDB Length = 256 Score = 154 bits (389), Expect = 2e-37, Method: Composition-based stats. Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 3/161 (1%) Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460 + ++ R + ++ E P++ EGND + G ++ ++++ +G++Y Sbjct: 2 SKNLIGRHLRLGSVEEQPFMFFATEG--CEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPD 59 Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 D K+GA + T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K Sbjct: 60 DRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKG 119 Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS 561 + V LD Y+ W I + + SR+S Sbjct: 120 EGTTLNQVLELLDQDKYK-WGVIGSRHPETLLKTHRDSRYS 159 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 57/149 (38%), Gaps = 9/149 (6%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 V+ + + +L Q + +G + + + + + + + ++ + V ++ Sbjct: 116 VVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRL------VDEGVELK 169 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 + +R G + ++ E + + CD VG S Y PK S + Sbjct: 170 DLNHAIETLR--GGLFVFIDEGPVLAHNLISD-CDVFSVGEEFQSFEYAFGLPKDSPYKS 226 Query: 759 PVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787 ++ +LK E+G +D L KW C Sbjct: 227 LIDSHLLKFREEGFIDILWEKWSSGNSVC 255 >3OEK-A nrPDB Length = 286 Score = 144 bits (363), Expect = 2e-34, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 69/156 (44%), Gaps = 20/156 (12%) Query: 643 MVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVF 696 + + D Q + +GT+ GST++ R + + M +YM Sbjct: 142 RGTTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQ--- 194 Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKG 753 EE + +++ K A++ ++ + Y+ ++ + C + +G + GYGIA KG Sbjct: 195 -PRVEEALTQLKAGKLD-AFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKG 252 Query: 754 SALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789 S + P++LA+L+ ++ L+ W G C + Sbjct: 253 SRWKRPIDLALLQFLGDDEIEMLERLWL--SGICHN 286 Score = 130 bits (327), Expect = 2e-30, Method: Composition-based stats. Identities = 45/176 (25%), Positives = 76/176 (43%), Gaps = 29/176 (16%) Query: 403 SVQNRTYIVTTILEDPYVMLKK--------------------------NANQFEGNDRYE 436 + V T+ E P+V+++ + Sbjct: 1 GDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCK 60 Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTIT 496 G+C+++ +A +G+SY L +V++GK+G + WNGM+GE+ Y RAD+A+ LTI Sbjct: 61 GFCIDILKRLAHTIGFSYDLYLVTNGKHGKKID--GVWNGMIGEVFYQRADMAIGSLTIN 118 Query: 497 LVREEVIDFSKPFMSLGISIMIKKPQK-SKPGVFSFLDPLAYEIWMCIVFAYIGVS 551 R E++DFS PF+ GIS+M+ + S F P + G + Sbjct: 119 EERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRPQEQYPPLKFGTVPNGST 174 >2RC9-A nrPDB Length = 294 Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 13/150 (8%) Query: 638 LTVERMVSPIESAEDLAKQTE---IAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694 + V + + D +GT+ S +++ R+S F +M YM+ Sbjct: 147 ILVRTRGTELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQS----FPEMHEYMRRYN-- 200 Query: 695 VFVRTTEEGMIRVRKSKGKY-AYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPK 752 V T +G+ ++ K A++++ + +Y + C + VG +GYGI P Sbjct: 201 --VPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPP 258 Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782 S L ++ + + G +D L KW+ Sbjct: 259 NSPLTSNISELISQYKSHGFMDVLHDKWYK 288 Score = 116 bits (289), Expect = 7e-26, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 37/156 (23%) Query: 408 TYIVTTILEDPYVMLKKNAN-----------------------------------QFEGN 432 V T++E P+V ++ + + Sbjct: 6 HLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFK 65 Query: 433 DRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAP 492 GYC++L ++A+ + + + L IV DGKYGA W G+VG+L+ G A++AV Sbjct: 66 KCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NGHWTGLVGDLLSGTANMAVTS 123 Query: 493 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 528 +I R +VIDF+ PF S + I+++ G+ Sbjct: 124 FSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGI 159 >5TUJ-C nrPDB Length = 235 Score = 131 bits (329), Expect = 2e-30, Method: Composition-based stats. Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 20/156 (12%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+ KN +Y G+ ++LA +AK +G + W+G Sbjct: 23 KPFSFKDKNG-------QYTGFDIDLAKALAKELGVKVEFVPTT-------------WDG 62 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536 ++ L G+ D+ ++ +TIT R++ +DFS P+M+ G +I++KK K F L+ Sbjct: 63 IIPALQTGKFDIVMSGMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLNKPD 122 Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEE 572 ++ + + + ++ +E ++E F+E Sbjct: 123 VKVAVQLGTTSEQAAKEFLPKAKIRTFENNAEAFQE 158 Score = 53.2 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 36/150 (24%), Positives = 56/150 (37%), Gaps = 22/150 (14%) Query: 638 LTVERMVSPIESAEDLAK---QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694 L + I+S EDL K + + GT + KEF ++KI FE Sbjct: 103 LVKKDNADKIKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE------------ 150 Query: 695 VFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKG 753 E V + A + +S + Y ++ P + V + G A KG Sbjct: 151 ----NNAEAFQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKG 205 Query: 754 SA-LRGPVNLAVLKLSEQGVLDKLKSKWWY 782 L VN + ++ + G DKL KW+ Sbjct: 206 DPELLNWVNNWLKQMKKDGTYDKLYEKWFK 235 >4ZDM-A nrPDB Length = 261 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 63/144 (43%), Gaps = 2/144 (1%) Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNA-NQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459 ++++ + I E P++ Y G VE+ + +++ + ++Y Sbjct: 2 SNNLNGMHLRLGIIPEMPFISEPSLGCTNIRDPSCYTGVNVEIVSMMSQDLNFTYNFITP 61 Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 D K+G ++ T WNG++ +L+ + D+ V L+ VR+ IDFS M G+ ++K Sbjct: 62 EDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALSNNAVRKADIDFSLSMMDGGLGALVK 121 Query: 520 KPQKSKPGVFSFLDPLAYEIWMCI 543 L+ Y+ W + Sbjct: 122 SDGTDLSHPLELLNQDKYQ-WGVV 144 Score = 62.5 bits (150), Expect = 8e-10, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 64/142 (45%), Gaps = 9/142 (6%) Query: 639 TVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698 V+ + + +L Q + +G +++ + + ++ A + ++ AE +V V Sbjct: 119 LVKSDGTDLSHPLELLNQDKYQWGVVDSRNPELLLASNQNADYNRI------AEDAVKVG 172 Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRG 758 + EG+ R+R G + ++ E Y + CD +++G K S + Sbjct: 173 SYGEGLERMRA--GGFVFIDEIPGINYAT-KGECDIVQIGETFQPFELAFGLRKNSPFKN 229 Query: 759 PVNLAVLKLSEQGVLDKLKSKW 780 V+ +L + EQGV+ +L +K+ Sbjct: 230 LVDTFMLGIREQGVISELYAKY 251 >3K4U-A nrPDB Length = 245 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 24/157 (15%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 P+ M K N G+ V+LA E+AK +G +L S W+G+ Sbjct: 17 PFEMKDKKGNVI-------GFDVDLAREMAKAMGVKLKLVPTS-------------WDGL 56 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537 + LV + D+ ++ +TI+ R ++F +P++ +G S+++KK + GV S+ D Sbjct: 57 IPGLVTEKFDIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEK--GVKSYKDLDKP 114 Query: 538 EIWMCIVFAYIG--VSVVLFLVSRFSPYEWHSEEFEE 572 E+ + F + LF ++ Y+ +E +E Sbjct: 115 ELTLVTKFGVSAEYAAKRLFKNAKLKTYDTEAEAVQE 151 Score = 41.7 bits (96), Expect = 0.002, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 61/165 (36%), Gaps = 24/165 (14%) Query: 626 IISSYTANLAAFLTVERMVSPIESAEDLAKQTEI----AYGTLEAGSTKEFFRRSKIAVF 681 + Y + L + + ++S +DL + E+ +G + K F+ +K+ + Sbjct: 84 FVEPYIVVGQSLLVKKGLEKGVKSYKDL-DKPELTLVTKFGVSAEYAAKRLFKNAKLKTY 142 Query: 682 EKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMN-EYIEQRKPCDTMKVGGN 740 + T E + V K ++ + N ++ Q+ + + + Sbjct: 143 D----------------TEAEAVQEVLNGKADM-FIFDLPFNVAFMAQKGQGYLVHLDTS 185 Query: 741 LDSKGYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784 L + G A KG +N + ++ G D+L +W+ D Sbjct: 186 LTYEPLGWAIKKGDPDFLNWLNHFLAQIKHDGSYDELYERWFVDT 230 >2RCB-A nrPDB Length = 292 Score = 120 bits (300), Expect = 4e-27, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 60/150 (40%), Gaps = 13/150 (8%) Query: 638 LTVERMVSPIESAEDLAKQTE---IAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694 + V + + D +GT+ S + + + S F +M +M+ Sbjct: 145 IMVRTRGTELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKAS----FPEMHAHMRRH--- 197 Query: 695 VFVRTTEEGMIRVRKSKGKY-AYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPK 752 TT G+ + K A++++ ++ +Y + C + VG +GYGI P+ Sbjct: 198 -SAPTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQ 256 Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782 S L ++ + + G +D L KW+ Sbjct: 257 NSPLTSNLSEFISRYKSSGFIDLLHDKWYK 286 Score = 119 bits (298), Expect = 6e-27, Method: Composition-based stats. Identities = 58/285 (20%), Positives = 100/285 (35%), Gaps = 48/285 (16%) Query: 409 YIVTTILEDPYVMLKKNANQFEGN---------------------------------DRY 435 V T++E P+V +++ + Sbjct: 7 LRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPRTLRRCC 66 Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 GYC++L +A+ + + + L IV DGKYGA W G+VG+L+ GRA +AV +I Sbjct: 67 YGYCIDLLERLAEDLAFDFELYIVGDGKYGALRD--GRWTGLVGDLLAGRAHMAVTSFSI 124 Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555 R +V+DF+ PF S + IM++ G+ + S + Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVRTRGTELSGIH-DPKLHHPSQGFRFGTVWE-SSAEAY 182 Query: 556 LVSRFSPYEWHSEEFEEGRDQ-------TTSDQSNEFGIFNSLWFSLGAFMQQGCDISPR 608 + + F H + + N F + SL + C + Sbjct: 183 IKASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSL-LDYEVSIDADCKLLTV 241 Query: 609 SLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 653 I G + L S T+NL+ F++ + I+ D Sbjct: 242 GKPFAIEG---YGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK 283 >4PSH-A nrPDB Length = 227 Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats. Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 22/175 (12%) Query: 402 SSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459 +++R Y++ + D P+ + +N N G+ V+LA EIA+ +G L+IV Sbjct: 3 DEIKSRGYLLVGLSADFPPFEFVDENGNI-------VGFDVDLAKEIARRLGV--ELKIV 53 Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 ++G++ L+ + DV ++ +TIT R++V+ FS P+ G I+++ Sbjct: 54 D-----------MTFDGLIPSLLTKKIDVIISGMTITEERKKVVAFSDPYFDAGQVIVVR 102 Query: 520 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGR 574 K +P + L + + V RF + E + GR Sbjct: 103 KDSDFRPKTYEDLVGKTVAVQIGTTGDIEVSKYDGIKVVRFDKFTDAFLELKRGR 157 Score = 36.3 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 12/93 (12%) Query: 702 EGMIRVRKSKGKYAYL-----------LESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 750 +G+ VR K A+L L+S + P D + G L S+ YGIA Sbjct: 136 DGIKVVRFDKFTDAFLELKRGRADAVVLDSATARAFVAKNP-DLVISSGVLSSEQYGIAV 194 Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783 K +VL+ ++ D L KW+ + Sbjct: 195 RKEDTDLLEFINSVLRELKKSPYDVLIEKWFSE 227 >4ZV2-A nrPDB Length = 233 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 21/157 (13%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 P+ +N + G+ ++LA IAK +G + + ++G+ Sbjct: 22 PFGFKDENG-------KLVGFDIDLAKAIAKKLGVKVEFKPMD-------------FDGI 61 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 537 + L G+ DV +A +TIT R++ +DFS P+ G +I++KK S L Sbjct: 62 IPALQSGKIDVVIAGMTITEERKKQVDFSDPYFEAGQAIVVKKGNDS-IKSLEDLKGKKV 120 Query: 538 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGR 574 + + V + ++ SE F+E + Sbjct: 121 GVQLGSTSEQHVKKVAKDAGVKVKKFDNFSEAFQELK 157 Score = 55.6 bits (132), Expect = 1e-07, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 59/146 (40%), Gaps = 16/146 (10%) Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFV 697 + V++ I+S EDL + G ++++ ++ K+ + Sbjct: 100 IVVKKGNDSIKSLEDLKGK---KVGVQLGSTSEQHVKKVAKDAGVKVKKF---------- 146 Query: 698 RTTEEGMIRVRKSKGKYAYLLESTM-NEYIEQRKPCDTMKVGGNLDSKGYGIATPKG-SA 755 E ++ + A + ++ + Y++Q VG + YGIA KG S Sbjct: 147 DNFSEAFQELKSGRVD-AVVTDNAVALAYVKQNPNAGVKIVGETFSGEPYGIAVRKGNSE 205 Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWW 781 L +N A+ ++ + G DK+ KW+ Sbjct: 206 LLEKINKALEEMKKDGTYDKIYEKWF 231 >5JOS-A nrPDB Length = 247 Score = 104 bits (258), Expect = 2e-22, Method: Composition-based stats. Identities = 30/166 (18%), Positives = 67/166 (40%), Gaps = 21/166 (12%) Query: 408 TYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466 T V T + P+ + +Y G+ +++A +AK +G + Sbjct: 24 TLRVGTTGDYKPFSYRDPDG-------QYTGFDIDVAKSLAKSLGVKVEFVPTT------ 70 Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526 W ++ +L + D+A+ +T+T R++ DFS P+M+ G + +++K K Sbjct: 71 -------WPTLMSDLQADKFDIAMGGVTVTPERQKKADFSDPYMTFGKTPLVRKEDADKF 123 Query: 527 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEE 572 ++ + + + ++ + YE + E F+E Sbjct: 124 KSLEDINRPDVRVAVNPGGTNEKFAREHLKKAKITVYENNVEIFQE 169 Score = 38.2 bits (87), Expect = 0.018, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 57/153 (37%), Gaps = 28/153 (18%) Query: 638 LTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFR----RSKIAVFE---KMWTYMKS 690 L + +S ED+ + ++ G+ ++F R ++KI V+E +++ + S Sbjct: 114 LVRKEDADKFKSLEDIN-RPDVRVAVNPGGTNEKFAREHLKKAKITVYENNVEIFQEVAS 172 Query: 691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 750 V + T E + +K G A L++ G Sbjct: 173 GRADVMITDTVEALYYAKKHPGLAAVLVD-------------------KPFTHSEKGYMM 213 Query: 751 PKG-SALRGPVNLAVLKLSEQGVLDKLKSKWWY 782 PKG VN + ++ +QG +KL KW Sbjct: 214 PKGDQEFLNYVNQWLDQMKQQGTYEKLYEKWLK 246 >4F3P-A nrPDB Length = 249 Score = 101 bits (251), Expect = 2e-21, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 21/137 (15%) Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487 +F+ D+Y G+ ++L AEIAK G++Y+++ + + G++ L D Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 547 VA++ +TI R + IDFS P+ G++ M++ + + ++ ++ A Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQANNTTIKSID--------DLNGKVIAAK 136 Query: 548 IGVSVVLFLVSRFSPYE 564 G + + ++ + P E Sbjct: 137 TGTATIDWIKAHLKPKE 153 Score = 45.5 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 57/154 (37%), Gaps = 21/154 (13%) Query: 630 YTANLAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYM 688 Y + LAA V+ + I+S +DL K GT K + +I F Sbjct: 107 YDSGLAA--MVQANNTTIKSIDDLNGKVIAAKTGTATIDWIKAHLKPKEIRQFP------ 158 Query: 689 KSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV-GGNLDSKGYG 747 ++ + + + A + ++ + + +KV G + YG Sbjct: 159 ----------NIDQAYLALEAGRVDAA-MHDTPNVLFFVNNEGKGRVKVAGAPVSGDKYG 207 Query: 748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781 I PKGS L VN + ++ G K+ KW+ Sbjct: 208 IGFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241 >1GGG-A nrPDB Length = 226 Score = 97.9 bits (242), Expect = 2e-20, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%) Query: 428 QFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRAD 487 +F+ D Y G+ V+L A IAK + Y L+ + ++G++ L D Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 531 +A+A +TIT R++ IDFS + G+ +M+K V Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDL 107 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 698 RTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATPKGSA- 755 + + + ++ A L ++ Y + VG +L+++ YGIA PKGS Sbjct: 137 PNIDNAYMELGTNRAD-AVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDE 195 Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWW 781 LR VN A+ L E G +++ KW+ Sbjct: 196 LRDKVNGALKTLRENGTYNEIYKKWF 221 >4IO3-A nrPDB Length = 248 Score = 95.6 bits (236), Expect = 8e-20, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 63/153 (41%), Gaps = 16/153 (10%) Query: 639 TVERMVSPIESAEDLAKQTEIAY---GTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSV 695 + R + I+ +DL K +I Y G + ++++ R + Sbjct: 109 ILMRKGTLIDGMDDL-KNGKIPYNRIGIRIGTAGEDYYLREISGGSRNFYP--------- 158 Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755 +++ +E + ++ ++ EY+ C+ VG + D +GI TPK Sbjct: 159 -LKSRQEMYDSLLAGIIDVSF-MDIGTAEYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWL 216 Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788 +++ +L L E G+LD LK KW+ K C Sbjct: 217 YAKDLDVNILSLRETGILDNLKKKWFQTKA-CP 248 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 54/122 (44%), Gaps = 10/122 (8%) Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGND-RYEGYCVELAAEIAKHVGYSYRLEIV 459 ++ ++ T + I P+ ++ + N + GY ++L + +G+ +++ Sbjct: 2 SARLKGITLRIGVIESVPFTIVANVIDTSGRNTTKLTGYVLDLIEYLRDKMGFVADVQLA 61 Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 P ++ G+V L G D+A+ +T+T R E++ FS + I+++ Sbjct: 62 ---------PPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNSMRILMR 112 Query: 520 KP 521 K Sbjct: 113 KG 114 >4H5F-A nrPDB Length = 243 Score = 91.0 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 58/129 (44%), Gaps = 17/129 (13%) Query: 405 QNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKY 464 + + + T+ P+ + +G ++ G +++A IA +G + Sbjct: 11 KGKLVVATSPDYAPFEF----QSLVDGKNQVVGADIDMAQAIADELGVKLEI-------- 58 Query: 465 GARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524 + +++ ++ L G+AD+AVA ++ T R+EV DFS P+ IS ++ K Sbjct: 59 -----LSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVHKADVE 113 Query: 525 KPGVFSFLD 533 K + L+ Sbjct: 114 KYKDLTSLE 122 >4YMX-A nrPDB Length = 260 Score = 85.2 bits (209), Expect = 1e-16, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 54/138 (39%), Gaps = 21/138 (15%) Query: 397 AGGDNSSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSY 454 ++ + IV D P+ K G D G+ +++A IAK +G Sbjct: 26 KFNTVDQIKQKGVIVMGTSADFPPFEFHKVEG----GKDEIVGFDIDIANAIAKKLGVKL 81 Query: 455 RLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514 ++ + + G++ L GR D+ +A +T T R++ +DFS + Sbjct: 82 EIKDMD-------------FKGLIPALQAGRVDMVIAGMTPTAERKKSVDFSDLYYDSRQ 128 Query: 515 SIMIKKPQKSKPGVFSFL 532 +++K S F L Sbjct: 129 VVVVK--NDSPISKFDDL 144 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 26/152 (17%) Query: 638 LTVERMVSPIESAEDLAKQT-EIAYGTLEAGSTKE--FFRRSKIAVFEKMWTYMKSAEPS 694 + V + SPI +DL +T + GT + K+ + ++ +M Sbjct: 129 VVVVKNDSPISKFDDLKVKTIAVQIGTTSEEAAKKIPNVKLKQLNRVSD--EFMDLQNGR 186 Query: 695 VFVRTTEEGMIR--VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPK 752 E+ + + +++ K ++ N G +A K Sbjct: 187 CDAIVVEDTVAKAYLKEYKDMKILYMDEINN------------------VENGSAVAVAK 228 Query: 753 GS-ALRGPVNLAVLKLSEQGVLDKLKSKWWYD 783 G+ +L VN + +L + G DKL KW+ Sbjct: 229 GNKSLLDVVNEVIKELKQSGEYDKLVDKWFKQ 260 >4G4P-A nrPDB Length = 244 Score = 83.7 bits (205), Expect = 3e-16, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 63/175 (36%), Gaps = 29/175 (16%) Query: 400 DNSSVQNRTYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEI 458 ++ + Y + T L P+ +Y G V+L IAK + L+ Sbjct: 16 YFQGMEGKKYTIGTDLTFAPFEFQDSKG-------KYIGIDVDLLDAIAKDQDFEVDLKP 68 Query: 459 VSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMI 518 + ++ V + + D +A ++IT R++ DFS P+ G+ + + Sbjct: 69 LG-------------FDSAVQAIQSKQIDGMIAGMSITDERKKSFDFSDPYFDSGLQLAV 115 Query: 519 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573 KK ++ V A +G FL Y++ + F++ Sbjct: 116 KKGNDKIKSYD--------DLKGKTVAAKVGTESANFLEKNKEKYDYTIKNFDDA 162 >4I62-A nrPDB Length = 269 Score = 80.6 bits (197), Expect = 3e-15, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 61/133 (45%), Gaps = 19/133 (14%) Query: 402 SSVQNRTYIVTTILED--PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 459 +++++ +V + D P+ K +G ++ G +ELA IA +G L + Sbjct: 33 EAIKSKGKLVVALNPDFAPFEYQK----VVDGKNQIVGSDIELAKAIATELGVELELSPM 88 Query: 460 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 S ++ ++ + G+AD+A++ ++ T R +V DFS P+ + +++K Sbjct: 89 S-------------FDNVLASVQSGKADLAISGVSKTDERSKVFDFSTPYYTAKNKLIVK 135 Query: 520 KPQKSKPGVFSFL 532 K + + L Sbjct: 136 KSDLATYQSVNDL 148 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 46/237 (19%), Positives = 93/237 (39%), Gaps = 31/237 (13%) Query: 552 VVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLS 611 +V+ L F+P+E+ ++ +G++Q ++ + ++ LG ++SP S Sbjct: 41 LVVALNPDFAPFEY--QKVVDGKNQIV---GSDIELAKAIATELGV----ELELSPMSFD 91 Query: 612 GRIVGGVWWFFTLIIISSYTANLAAFLTVER-----MVSPIESAEDL---AKQTEIAYGT 663 ++ V + IS + T ER +P +A++ K Y + Sbjct: 92 N-VLASVQSGKADLAISGVSK------TDERSKVFDFSTPYYTAKNKLIVKKSDLATYQS 144 Query: 664 LEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMN 723 + + K+ K ++ E M + V + + ++ + A + E + Sbjct: 145 VNDLAQKK-VGAQKGSIQETMAKDLLQNSSLVSLPKNGNLITDLKSGQVD-AVIFEEPVA 202 Query: 724 EYIEQRKPCDTMKVGGNLDSK---GYGIATPKGSA-LRGPVNLAVLKLSEQGVLDKL 776 + + P D N + + Y +A K S L+ V+ + KL E G LDKL Sbjct: 203 KGFVENNP-DLAIADLNFEKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKL 258 >2Q2A-A nrPDB Length = 272 Score = 79.1 bits (193), Expect = 9e-15, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 44/113 (38%), Gaps = 21/113 (18%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+ ++K + G+ V+L + K G Y L+ W+ Sbjct: 53 APFEYMQK--------GKIVGFDVDLLDAVMKAAGLDYELK-------------NIGWDP 91 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529 + L D+ ++ +TIT R++ DFS P+ I++K+ K + Sbjct: 92 LFASLQSKEVDMGISGITITDERKQSYDFSDPYFEATQVILVKQGSPVKNALD 144 Score = 49.0 bits (115), Expect = 1e-05, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 63/151 (41%), Gaps = 20/151 (13%) Query: 635 AAFLTVERMVSPIESAEDLAKQT-EIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEP 693 A + + + SP+++A DL +T + T + ++ F + ++K E Sbjct: 127 ATQVILVKQGSPVKNALDLKGKTIGVQNATTGQEAAEKLFGKG---------PHIKKFET 177 Query: 694 SVFVRTTEEGMIRVRKSKGKYAYLLESTM-NEYIEQRKPCDTMKVG--GNLDSKGYGIAT 750 +V ++ + A + ++ + NEY++ + N S+ YG+ Sbjct: 178 TVV------AIMELLNGGVD-AVITDNAVANEYVKNNPNKKLQVIEDPKNFASEYYGMIF 230 Query: 751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781 PK S L+ V+ A+ + G ++ KW+ Sbjct: 231 PKNSELKAKVDEALKNVINSGKYTEIYKKWF 261 >4ZEF-A nrPDB Length = 251 Score = 73.7 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 60/179 (33%), Gaps = 28/179 (15%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+ + Y G V+L A+ G++ + + ++ Sbjct: 39 APFEFQNAQGD-------YVGIDVDLVKRAAELQGFTVEFKFIG-------------FSS 78 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536 V + G+AD VA +TIT R++ DFS P+ GI I +KK + S+ D Sbjct: 79 AVQAVESGQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKKGND---KIKSYDDLKG 135 Query: 537 YEIWMCIV-----FAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNS 590 ++ + I F + + + E G D G + Sbjct: 136 KKVGVKIGTESADFLEKNKKKYDYSIKYLDTTDALYSALEIGEVDAMMDDYPVIGYGVA 194 >2PYY-A nrPDB Length = 228 Score = 69.8 bits (169), Expect = 5e-12, Method: Composition-based stats. Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 687 YMKSAEPSVF-VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSK 744 Y++ SV V EE ++ K A + ++ + + + VG L + Sbjct: 126 YLREHHISVLEVPKIEEAYKALQTKKAD-AVVFDAPVLLFYAANEGKGKVEIVGSILREE 184 Query: 745 GYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784 YGI P S R P+N A+L L E G L KW+ K Sbjct: 185 SYGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWFDPK 224 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 47/111 (42%), Gaps = 20/111 (18%) Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468 +V T + P+V G+ ++L IA +G +L +Y + Sbjct: 5 LLVATRVIPPFV--------LSNKGELSGFSIDLWRSIATQIGIESKLI-----EYSSVP 51 Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519 ++ + + ++ +A ++IT RE+ DFS P + G+ IM++ Sbjct: 52 E-------LISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95 >5HPQ-A nrPDB Length = 255 Score = 69.0 bits (167), Expect = 9e-12, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 50/125 (40%), Gaps = 20/125 (16%) Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469 + TT P+ + Y G+ V++A +A+ +G + S Sbjct: 27 VATTGDYKPFSYRTEEG-------GYAGFDVDMAQRLAESLGAKLVVVPTS--------- 70 Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529 W ++ + R D+A++ ++I L R+ FS P++ G + + ++++ Sbjct: 71 ----WPNLMRDFADDRFDIAMSGISINLERQRQAYFSIPYLRDGKTPITLCSEEARFQTL 126 Query: 530 SFLDP 534 +D Sbjct: 127 EQIDQ 131 >5X2N-B nrPDB Length = 478 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 53/455 (11%), Positives = 137/455 (30%), Gaps = 98/455 (21%) Query: 20 NFPNNIQIGGLFPNQQSQEH------------------------AAFRFALSQLTEPPKL 55 + P +I++GGLFP ++ ++A+ ++ +L Sbjct: 14 SMPGDIKLGGLFPIKEQSNEVSNDLTKLNSVSCDSLNKDGLGRALVMKYAVEEINANSQL 73 Query: 56 LPQID----------------------IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRT 93 LP + + S+ + + + A+ G Sbjct: 74 LPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVECNYTDYETDMVAVIGPQSSEM 133 Query: 94 VNMLTSFCGALHVCFITPSFPVDTSN------QFVLQLRPELQE--ALISIIDHYKWQTF 145 V ++ G + I+ D + F + ++++ A++ +I + W Sbjct: 134 VTVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVPSDIRQVDAMVQLIKKFNWNWV 193 Query: 146 VYI-YDADRGLSVLQRVLDTAAEKNWQVTAVNIL---TTTEEGYRMLFQDLEKKKERLVV 201 + + + G +Q+ A + V ++ + + + +++ + ++VV Sbjct: 194 AVVGSEEEYGQQGVQQFSKKAEDMGVCVAYQGLIPIYDDPKPAIQTIINNIQTTEVKVVV 253 Query: 202 VDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKE--SGANVTGFQLVNYT 259 V + +++K G +I ++ + + S V GF T Sbjct: 254 VFSLVSPAVSFFEEVIKKNLTG---VWIASSSWAISDKVYSLPNIDSIGTVIGFIDETET 310 Query: 260 DTIPARIMQQWRTSDARDHTRVDWKRPKY-----------------------TSALTYDG 296 + + + + P T+ Y Sbjct: 311 LELLSPFTEVLFKKIHEASPTEKPEDPYNPCPECWSLSPANVSLVKEESVQRTAFSVYAA 370 Query: 297 VKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFN 356 V +A A L + ++ PW + L++ +++F+ Sbjct: 371 VYTVAHALHKLLECNSAACKWSSSTRLY-----PWK----LLEVLKEFSVNISNTSLKFD 421 Query: 357 EKGRRTNYTLHVIE--MKHDGIRKIGYWNEDDKFV 389 + G N VI+ ++ + +G + + + Sbjct: 422 QNG-NPNIGYSVIQRIWENQSLSSVGSYRSANLSI 455 >4OEN-A nrPDB Length = 223 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 59/157 (37%), Gaps = 29/157 (18%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+V + ++Y G +EL IAK G+ + ++ Sbjct: 14 APFVFQNSS-------NQYTGIDMELIKAIAKDQGFEIEI-------------TNPGFDA 53 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536 + + G+AD +A +++T R+ DFS+ + + + +K + S+ D Sbjct: 54 AISAVQAGQADGIIAGMSVTDARKATFDFSESYYTANTILGVK----ESSNIASYED--- 106 Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573 + V G + FL S Y + + F +G Sbjct: 107 --LKGKTVGVKNGTASQTFLTENQSKYGYKIKTFADG 141 >4KPT-A nrPDB Length = 251 Score = 66.0 bits (159), Expect = 7e-11, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 22/143 (15%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G ++ G V++ E+AK + + ++ + L G+ D + Sbjct: 46 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 92 Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 550 A +TIT R+E DFS P+ + ++I K K ++ V A G Sbjct: 93 AGMTITDERKETFDFSNPYYTSALTIATTKDSKLS---------DYSDLKGKAVGAKNGT 143 Query: 551 SVVLFLVSRFSPYEWHSEEFEEG 573 + +L Y + + + +G Sbjct: 144 AAQTWLQENQKKYGYTIKTYSDG 166 >6FXG-A nrPDB Length = 227 Score = 65.6 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 22/143 (15%) Query: 431 GNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490 G ++ G V++ E+AK + + ++ + L G+ D + Sbjct: 22 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 68 Query: 491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 550 A +TIT R+E DFS P+ + ++I K K ++ V A G Sbjct: 69 AGMTITDERKETFDFSNPYYTSALTIATTKDSKLS---------DYSDLKGKAVGAKNGT 119 Query: 551 SVVLFLVSRFSPYEWHSEEFEEG 573 + +L Y + + + +G Sbjct: 120 AAQTWLQENQKKYGYTIKTYSDG 142 >5EYF-A nrPDB Length = 245 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 15/109 (13%) Query: 436 EGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTI 495 +G+ V++A I K + + +GK + +K + L G D +A +TI Sbjct: 39 QGFDVDIAKAITKKI-------LGDNGKTEFVEVTSKT---RIPLLKNGNIDAIIATMTI 88 Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 544 T R++ +DFS + G ++++KK + K +D L + V Sbjct: 89 TDERKKQVDFSDVYFDAGQALLVKKGSQIKS-----VDDLNASTTVLAV 132 Score = 53.2 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 57/146 (39%), Gaps = 17/146 (11%) Query: 642 RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTE 701 + S I+S +DL T + ++ ++ R+ + + Sbjct: 112 KKGSQIKSVDDLNASTTVL--AVKGSTSAANIRQHAPDA------------KILELENYA 157 Query: 702 EGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA-LRGPV 760 E ++ +G A ++ + I P + VGG ++ YGIA KG V Sbjct: 158 EAFTALQSGQGD-AMTTDNAILLGIADENP-EYELVGGTFTNEPYGIAINKGQENFLKAV 215 Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGE 786 N A+ ++ G DK+ KW+ ++ E Sbjct: 216 NQALEEMHADGTYDKIYQKWFPNETE 241 >4F3S-A nrPDB Length = 255 Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 37/180 (20%), Positives = 72/180 (40%), Gaps = 27/180 (15%) Query: 402 SSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461 S V+ RT V P ++ K + +G +EL + + Sbjct: 4 SIVEGRTLNVAVSPASPPMLFKSAD------GKLQGIDLELFSSYCQS------------ 45 Query: 462 GKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 521 ++ + AW+GM+G + G+ADVA + ++IT R++VIDFS+P+ ++ Sbjct: 46 -RHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSF-YLVSMA 103 Query: 522 QKSKPGVFSFLDPLAYEIWMCIVFAY------IGVSVVLFLVSRFSPYEWHSEEFEEGRD 575 K + + + Y I AY + +S+ Y ++E + ++ Sbjct: 104 N-HKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKN 162 Score = 35.1 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Query: 696 FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRK-PCDTMKVGGNLDSKGYGIATPKGS 754 T E M ++ A++ E + ++K P ++ V N+D GIA KGS Sbjct: 149 LYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQ--LGIAFKKGS 206 Query: 755 ALRGPVNLAVLKLSEQG 771 +R N L L EQG Sbjct: 207 PVRDDFN---LWLKEQG 220 >4MS4-A nrPDB Length = 420 Score = 62.1 bits (149), Expect = 9e-10, Method: Composition-based stats. Identities = 68/413 (16%), Positives = 134/413 (32%), Gaps = 45/413 (10%) Query: 23 NNIQIGGLFPNQQ-----SQEHAAFRFALSQLTEPPKLLPQIDIVNIS-----DSFEMTY 72 + IG LFP A AL + +LP ++ I D + T Sbjct: 4 RAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK 63 Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCG------ALHVCFITPSFPVDTSNQFVLQLR 126 I +V+ L + L +P+ + Sbjct: 64 YLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTH 123 Query: 127 PEL---QEALISIIDHYKWQTFVYIY-DADRGLSVLQRVLDTAAEKNWQVTAVNILTTTE 182 P + + + + W+ I + S L + + E ++T + Sbjct: 124 PSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQ---SFF 180 Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFM------ 236 + ++L+++ R++V + ++ K G Y + L Sbjct: 181 SDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIY 240 Query: 237 ----DIDLNKFKESGANVTGFQLV----NYTDTIPARIMQQWRTSDARDHTRVDWKRPKY 288 + +++ E+ ++V T +I Q++ + R + + Sbjct: 241 DPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGF 300 Query: 289 TSA-LTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347 A L YD + +A A + S N + I RA+ FE Sbjct: 301 QEAPLAYDAIWALALAL-NKTSGGGGRSGVRLEDFNYNNQTITDQ----IYRAMNSSSFE 355 Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE-DDKFVPAATDAQAGG 399 G++G+V F+ G R +TL + +++ +KIGY++ D + TD GG Sbjct: 356 GVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGG 407 >5X2M-A nrPDB Length = 461 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 67/430 (15%), Positives = 126/430 (29%), Gaps = 89/430 (20%) Query: 16 VVGANF--PNNIQIGG-LFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTY 72 V ANF P I LF + RF++ ++ LLP + + F+ Sbjct: 26 VAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSL--GYQMFD--- 80 Query: 73 RFCSQFSK--GVYAIFGFYE--RRTVNMLTSFCGALHVCF---------ITPSFPVDTSN 119 CS G++ + + R + T A+ V I P F + Sbjct: 81 -HCSDIHSFPGIFKLLSVNDLIRPWEDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLFP 139 Query: 120 ------------------QFVLQLR--PELQEALISIIDHYKWQTFVYIYDADRGLSVLQ 159 F+ + ++ A++ II ++ W+ ++Y D Sbjct: 140 MVSYGCSGSVFSKENLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGL 199 Query: 160 RVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKL 219 E + A Y +F+ +E++ +++VV A++ V+L Sbjct: 200 EQFKNKIEDSEICLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQL 259 Query: 220 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHT 279 +I D + ++ G Q + + ++ +D Sbjct: 260 NVTNK--VWI-------ADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSA 310 Query: 280 RVDWKRPKYTSAL--------------------------TYDGVKVMAEAFQSLRRQRID 313 + Y V +A A + Sbjct: 311 ISQTDGGDTEQKMFCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTL----- 365 Query: 314 ISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH 373 R + C N V I L++ F L VQF+E G +L V+ Sbjct: 366 ---RCGSDRCPKNITV---HPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVVFWNS 419 Query: 374 DG-IRKIGYW 382 G ++G + Sbjct: 420 SGNAEEVGSY 429 >4F11-A nrPDB Length = 433 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 45/311 (14%), Positives = 102/311 (32%), Gaps = 30/311 (9%) Query: 104 LHVCFITPSFPVDTSNQFVLQLRPE---LQEALISIIDHYKWQTFVYIYDADRGLSVLQR 160 L TP + + P + A++ ++ HY+W+ + + S ++ Sbjct: 113 LSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRN 172 Query: 161 VLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLE 220 L T + + + + + + L+ R+++ + + + Sbjct: 173 DL-TGVLYGEDIEISDTESFSND-PCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEEN 230 Query: 221 KNGIGYHYILANLGFMDIDLNKFKESGAN------------VTGFQLVNYT---DTIPAR 265 G Y +I+ G+ + + + AN + G+ V++ Sbjct: 231 MYGSKYQWIIP--GWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKT 288 Query: 266 IMQQWRTSDARDHTRVDWKR-PKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCL 324 I + R++ P YDG+ V+A ++ ++ + + Sbjct: 289 ISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIA----KTLQRAMETLHASSRHQRI 344 Query: 325 ANPAVPWGQ-GIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWN 383 + G I A+ + F G+TG V F G R T+ + + K+G +N Sbjct: 345 QDFNYTDHTLGRIILNAMNETNFFGVTGQVVF-RNGERMG-TIKFTQFQDSREVKVGEYN 402 Query: 384 EDDKFVPAATD 394 + D Sbjct: 403 AVADTLEIIND 413 >4KQP-A nrPDB Length = 232 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 54/142 (38%), Gaps = 21/142 (14%) Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491 + ++ G V+L IAK+ G+ + + + V + G AD ++ Sbjct: 27 DKQFTGIDVDLLNAIAKNQGFKLKWNFIG-------------FQAAVDSVQSGHADGMMS 73 Query: 492 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 551 ++IT R++V D+ P+ S ++I S ++ + A G + Sbjct: 74 GMSITDARKQVFDYGSPYYSSNLTIATSSTDDSIKSW--------KDLKGKTLGAKNGTA 125 Query: 552 VVLFLVSRFSPYEWHSEEFEEG 573 +L + Y + + F + Sbjct: 126 SFDYLNAHAKEYGYTVKTFTDA 147 >3TQL-A nrPDB Length = 227 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 41/103 (39%), Gaps = 20/103 (19%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 PYV + + + EG+ ++ + K + + + W+ + Sbjct: 14 PYVYMGPSG-------QVEGFGADIVKAVCKQMQAVCTI-------------SNQPWDSL 53 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520 + L G+ D + IT R++ +DF+ P+ + +S + K Sbjct: 54 IPSLKLGKFDALFGGMNITTARQKEVDFTDPYYTNSVSFIADK 96 >2IEE-A nrPDB Length = 271 Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 13/107 (12%) Query: 426 ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGR 485 + G+D+ GY VE+ E AK +G + + +GM+ + G+ Sbjct: 37 HDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMGI-------------DGMLTAVNSGQ 83 Query: 486 ADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532 D A + +T REE FS P+ + +++K S L Sbjct: 84 VDAAANDIDVTKDREEKFAFSTPYKYSYGTAIVRKDDLSGIKTLKDL 130 >5OTA-A nrPDB Length = 265 Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 13/88 (14%) Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 + + G+ ++L ++ K + + +AW+G++ L GR D Sbjct: 22 DAGGKLIGFDIDLGNDLCKRMNIECKF-------------VEQAWDGIIPSLTAGRYDAI 68 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIM 517 +A + I RE+VI FS+P++ ++ + Sbjct: 69 MAAMGIQPAREKVIAFSRPYLLTPMTFL 96 >2Y7I-A nrPDB Length = 229 Score = 59.8 bits (143), Expect = 6e-09, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 50/118 (42%), Gaps = 22/118 (18%) Query: 402 SSVQNRTYIVTTILE-DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460 +SV RT T PY + +++ G+ +++A + K + Sbjct: 1 ASVSARTLHFGTSATYAPYEFVD-------ADNKIVGFDIDVANAVCKEMQAECSF---- 49 Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMI 518 ++++ ++ L + + D +A + +T RE+ + FS+P+ G+S ++ Sbjct: 50 ---------TNQSFDSLIPSLRFKKFDAVIAGMDMTPKREQQVSFSQPYYE-GLSAVV 97 >3VV5-A nrPDB Length = 260 Score = 59.0 bits (141), Expect = 9e-09, Method: Composition-based stats. Identities = 23/146 (15%), Positives = 56/146 (38%), Gaps = 18/146 (12%) Query: 427 NQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRA 486 N F+ ++ G+ V+L IA+ +G ++++ ++ +L GR Sbjct: 50 NYFDERNQLTGFEVDLGNAIAERLGLK-------------PRWIAQSFDTLLIQLNQGRF 96 Query: 487 DVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 546 D +A IT R +DF+ P G +++ + + D + + + Sbjct: 97 DFVIASHGITEERARAVDFTNPHYCTG-GVIVSRKGGPRTA----KDLQGKVVGVQVGTT 151 Query: 547 YIGVSVVLFLVSRFSPYEWHSEEFEE 572 Y+ + + + Y+ + ++ Sbjct: 152 YMEAAQKIPGIKEVRTYQRDPDALQD 177 Score = 37.4 bits (85), Expect = 0.031, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Query: 686 TYMKSAEPSVFVRTT------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG 739 TYM++A+ ++ + + + + E I++RK +T++VG Sbjct: 151 TYMEAAQKIPGIKEVRTYQRDPDALQDLLAGRIDTWITDRFVAKEAIKERKLENTLQVGE 210 Query: 740 NLDSKGYGIATPKGS-ALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGEC 787 + + +A KG+ +L +N A+ +L + G ++ KW+ + C Sbjct: 211 LVFQERVAMAVAKGNKSLLDALNRALAELMQDGTYARISQKWFGEDVRC 259 >5K5S-A nrPDB Length = 615 Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 38/290 (13%), Positives = 99/290 (34%), Gaps = 39/290 (13%) Query: 44 FALSQLTEPPKLLPQIDI--------VNISDSFEMTYRF----------------CSQFS 79 FA+ ++ P LLP + + +S + E T F CS+ Sbjct: 76 FAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHI 135 Query: 80 KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV------DTSNQFVLQLRPELQEA- 132 A+ G + + G ++ ++ + + F+ + + +A Sbjct: 136 PSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQAT 195 Query: 133 -LISIIDHYKWQTF-VYIYDADRGLSVLQRVLDTAAEKN--WQVTAVNILTTTEEGYRML 188 + II++++W D D G +++ + A E++ + + + EE + + Sbjct: 196 AMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHV 255 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMD--IDLNKFKES 246 + ++ +++VV L ++ +IV+ G ++ + I + ++ Sbjct: 256 VEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHV 313 Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDG 296 GF L +++ + + + + +G Sbjct: 314 VGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEG 363 >5FBH-B nrPDB Length = 568 Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 38/290 (13%), Positives = 99/290 (34%), Gaps = 39/290 (13%) Query: 44 FALSQLTEPPKLLPQIDI--------VNISDSFEMTYRF----------------CSQFS 79 FA+ ++ P LLP + + +S + E T F CS+ Sbjct: 103 FAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHI 162 Query: 80 KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV------DTSNQFVLQLRPELQEA- 132 A+ G + + G ++ ++ + + F+ + + +A Sbjct: 163 PSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQAT 222 Query: 133 -LISIIDHYKWQTF-VYIYDADRGLSVLQRVLDTAAEKN--WQVTAVNILTTTEEGYRML 188 + II++++W D D G +++ + A E++ + + + EE + + Sbjct: 223 AMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHV 282 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMD--IDLNKFKES 246 + ++ +++VV L ++ +IV+ G ++ + I + ++ Sbjct: 283 VEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHV 340 Query: 247 GANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDG 296 GF L +++ + + + + +G Sbjct: 341 VGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEG 390 >5LOM-A nrPDB Length = 269 Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 57/139 (41%), Gaps = 20/139 (14%) Query: 387 KFVPAATDAQAGGDNSSVQNRTYIVTTI-LEDPYVMLKKNANQFEGNDRYEGYCVELAAE 445 VP + + T V T+ PY + N + G+ +EL Sbjct: 13 GLVPRGS--HMDNPLGLIDPTTISVGTMGDAKPYAFTTADGN-------FTGFDIELFLN 63 Query: 446 IAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDF 505 +A +G+ ++V G+ ++ ++ + GR DVA A + T R+E +DF Sbjct: 64 VAGRLGFKKE-QVVFTGQ---------EFSALMPSVANGRFDVAAAAIGTTAKRKETVDF 113 Query: 506 SKPFMSLGISIMIKKPQKS 524 S +++ +S++ + + Sbjct: 114 SDGYLAGFLSVLTSEAGIT 132 Score = 35.5 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 19/153 (12%) Query: 634 LAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAE 692 LA FL+V + I A L K+ + GTL+ ++ F + + F Sbjct: 118 LAGFLSVLTSEAGITDAAGLKGKRLGVVQGTLQEIYAEKNFAGTDLVKFPD--------- 168 Query: 693 PSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPK 752 + + +L +Y + + D+ G K Sbjct: 169 -------NNSAVSALNNGTVDAHFLDFEAAKDYSARYPALKIAVNIPSFDAPA-GFVIRK 220 Query: 753 GSA-LRGPVNLAVLKLSEQGVLDKLKSKWWYDK 784 G+ LR ++ + + + G KL KW+ Sbjct: 221 GNDALRNALDKGLKEAMQDGTWKKLHEKWFPGT 253 >5ORE-A nrPDB Length = 263 Score = 57.5 bits (137), Expect = 3e-08, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 46/107 (42%), Gaps = 15/107 (14%) Query: 432 NDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVA 491 + +G+ ++LA + + + ++ + W+G++ L + D +A Sbjct: 23 GGKLDGFEIDLANALCEKMKAKCQI-------------VAQNWDGIMPSLTGKKYDAIMA 69 Query: 492 PLTITLVREEVIDFSKPFMS--LGISIMIKKPQKSKPGVFSFLDPLA 536 +++T R+EVI FS P+ + G ++M PG+ + Sbjct: 70 AMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGLGETYSLDS 116 Score = 32.8 bits (73), Expect = 0.76, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 6/91 (6%) Query: 697 VRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKG-YGI---ATPK 752 ++ EE + + + A L +T+ ++ K+ G L S G +G+ K Sbjct: 162 YKSVEEHNLDLTSGRLD-AVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAVGLRK 220 Query: 753 -GSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782 +AL+ + A+ SE G + L KW+ Sbjct: 221 EDTALKADFDAAIKAASEDGTIKTLSLKWFK 251 >1HSL-A nrPDB Length = 238 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 21/155 (13%), Positives = 48/155 (30%), Gaps = 28/155 (18%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+ G+ ++LA E+ K + + Sbjct: 15 APFESKNAQGE-------LVGFDIDLAKELCKRINTQCTF-------------VENPLDA 54 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536 ++ L + D ++ L+IT R++ I F+ + +++ K S + P Sbjct: 55 LIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKN--------SDIQPTV 106 Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFE 571 + V G + F ++P ++ Sbjct: 107 ASLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQ 141 >3I6V-A nrPDB Length = 232 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 38/93 (40%), Gaps = 20/93 (21%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 PY + +G+ EL E+ K G + W+ + Sbjct: 17 PYNFINDAGEV-------DGFERELGDELCKRAGLTCE-------------WVKNDWDSI 56 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFM 510 + LV G D +A ++IT R+EVIDF++ ++ Sbjct: 57 IPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 58/160 (36%), Gaps = 6/160 (3%) Query: 625 IIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKM 684 ++ +Y +A + I+ ++ T +Y G+ ++ A + Sbjct: 60 LVSGNYDTIIAGMSITDERDEVIDFTQNYIPPTASSYVATSDGADLSGIVAAQTATIQAG 119 Query: 685 WTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSK 744 + +S V T EE + VR + + + I + M VG ++ Sbjct: 120 Y-IAESGATLVEFATPEETIAAVRNGEADAVFA-DRDYLVPIVAESGGELMFVGDDVPLG 177 Query: 745 GYGIAT---PKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781 G G+ LRG + A+ + E G L+ + KW+ Sbjct: 178 G-GVGMGLRESDGELRGKFDAAITSMKEDGTLNTMIKKWF 216 >1IIT-A nrPDB Length = 232 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 54/136 (39%), Gaps = 21/136 (15%) Query: 409 YIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARD 468 V + P+V + N + G +++ +A+ ++ Y ++ Sbjct: 6 LKVGVVGNPPFVFYGE-----GKNAAFTGISLDVWRAVAESQKWNSE--------YVRQN 52 Query: 469 PDTKAWNGMVGELVYGRADVAVAPLTITLVREEV--IDFSKPFMSLGISIMIKKPQKSKP 526 + + + G D+ + P+++T R + I F++P+ S GI ++I P + P Sbjct: 53 SISAG----ITAVAEGELDILIGPISVTPERAAIEGITFTQPYFSSGIGLLI--PGTATP 106 Query: 527 GVFSFLDPLAYEIWMC 542 S D E+ + Sbjct: 107 LFRSVGDLKNKEVAVV 122 Score = 33.2 bits (74), Expect = 0.51, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 33/92 (35%), Gaps = 1/92 (1%) Query: 691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIA 749 + V I + + K A + + Y ++ P + + + YG Sbjct: 134 YQADVRETNNLTAAITLLQKKQVEAVMFDRPALIYYTRQNPNLNLEVTEIRVSLEPYGFV 193 Query: 750 TPKGSALRGPVNLAVLKLSEQGVLDKLKSKWW 781 + S L+ +N+ +L L V+ + +W Sbjct: 194 LKENSPLQKTINVEMLNLLYSRVIAEFTERWL 225 >1ISS-A nrPDB Length = 490 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 52/354 (14%), Positives = 112/354 (31%), Gaps = 58/354 (16%) Query: 82 VYAIFGFYERRTVNMLTSFCGALHVCFITPS-----FPVDTSNQFVLQLRPE---LQEAL 133 + + G + + + I S T ++ L++ P A+ Sbjct: 124 IAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAM 183 Query: 134 ISIIDHYKWQTFVYIYDA-DRGLSVLQRVLDTAAEKNWQVTAVNIL--TTTEEGYRMLFQ 190 + I+ Y W ++ + G S + + AA++ + + + E+ + L + Sbjct: 184 LDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLR 243 Query: 191 DLEKK--KERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248 L ++ K R+VV CE + +L + +L G ++ + G+ D D + Sbjct: 244 KLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGE--FSLIGSDGWADRD-EVIEGYEV 300 Query: 249 NVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDW------------------------- 283 G + + +TR W Sbjct: 301 EANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKK 360 Query: 284 ---KRPKYTSALTYDG-VKVMAEAFQSL---RRQRIDISRRGNAGDCLANPAVPWGQGID 336 D + + A ++ + G+ G C A + G Sbjct: 361 VCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPID---GRK 417 Query: 337 IQRALQQVRFEGLTG-NVQFNEKGRRTNYTLHVIEMKHDGIRK-----IGYWNE 384 + L + F G++G V F+EKG ++ +++ + +G W+E Sbjct: 418 LLDFLIKSSFVGVSGEEVWFDEKGDAPG-RYDIMNLQYTEANRYDYVHVGTWHE 470 >3DEL-B nrPDB Length = 242 Score = 53.6 bits (127), Expect = 4e-07, Method: Composition-based stats. Identities = 27/168 (16%), Positives = 59/168 (35%), Gaps = 25/168 (14%) Query: 418 PYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGM 477 P+ + K G+ ++LA EI+ +G + + +++ + Sbjct: 23 PFEFVDKRGEV-------VGFDIDLAREISNKLGKTLDVR-------------EFSFDAL 62 Query: 478 VGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPL 535 + L R D + ++IT R + I P+ I +++ K + P + + Sbjct: 63 ILNLKQHRIDAVITGMSITPSRLKEI-LMIPYYGEEIKHLVLVFKGENKHPLPLTQYRSV 121 Query: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSN 583 A + AY+ + + S S E E G+ + + Sbjct: 122 AVQT-GTYQEAYLQSLSEVHIRSFDSTLEVLME-VMHGKSPVAVLEPS 167 >5OWF-A nrPDB Length = 259 Score = 52.5 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Query: 430 EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVA 489 + + G+ ++L E+ K + ++ ++ L + D Sbjct: 42 DAKGEFIGFDIDLGNEMCKRMQVK-------------CTWVASDFDALIPSLKAKKIDAI 88 Query: 490 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 531 ++ L+IT R++ I FS + ++ K +P + S Sbjct: 89 ISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLESL 130 >1YK0-A nrPDB Length = 480 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 49/374 (13%), Positives = 105/374 (28%), Gaps = 54/374 (14%) Query: 31 FPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYE 90 + A R T L P + + R V A G Sbjct: 69 LTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKP 128 Query: 91 RRTVNMLTSFCGALHVCFITPSFPV---------------DTSNQFVLQLRPE---LQEA 132 + + + A V + + + D+ + ++ P + E Sbjct: 129 DLILGPVCEYAAA-PVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEM 187 Query: 133 LISIIDHYKWQTFVYIYDADR----GLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRML 188 ++++ H+ W +Y D+ L+ V + E+ + + T + + Sbjct: 188 MLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDI 247 Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248 +++ + ER+V++ S+ + +I+ + Y + L + + G Sbjct: 248 VRNI-QASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGD 306 Query: 249 N--------VTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALT---YDGV 297 + Q V T+ +++ + Y + +D + Sbjct: 307 KHDFEAKQAYSSLQTVTLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAI 365 Query: 298 KVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE 357 + A + R G N FEG+ G V + Sbjct: 366 LLYVLALHEVLRAGYSKKDGGKIIQQTWNR-----------------TFEGIAGQVSIDA 408 Query: 358 KGRRTNYTLHVIEM 371 G R VI M Sbjct: 409 NGDR-YGDFSVIAM 421 >3A3K-A nrPDB Length = 435 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 50/405 (12%), Positives = 127/405 (31%), Gaps = 63/405 (15%) Query: 41 AFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAI-----------FGFY 89 A AL+++ P LLP + + S E CS + + A+ G Sbjct: 26 AVELALARVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPG 85 Query: 90 ERRTVNMLTSFCGALHVCFIT---PSFPVDTSNQFVLQLRPELQEALI-----SIIDHYK 141 + + F V +T P+ + +++ L R + ++ Sbjct: 86 CVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLG 145 Query: 142 WQTFVYIYDADRGLSV-----LQRVLDTAAEKNWQVT-AVNILTTTEEGYRMLFQDLEKK 195 W+ + ADR + L + +T + + ++ Sbjct: 146 WEHQALVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLLRAVRR 205 Query: 196 KERLVVVDCESERLNAILGQIVKLEKNGIGYHY---------------ILANLGFMDIDL 240 K R++ + + ++ + G Y + ++ + D Sbjct: 206 KGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKSAQGLVPQKPWERGDG 265 Query: 241 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTR----VDWKRPKYTSALTYDG 296 + + +++ Y + ++ + + V+ A +DG Sbjct: 266 QD-RSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTVEDGLKNIIPASFHDG 324 Query: 297 VKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFN 356 + + +A Q ++ G +I + + F+G+TG ++ + Sbjct: 325 LLLYVQAVTETLAQGGTVTD-----------------GENITQRMWNRSFQGVTGYLKID 367 Query: 357 EKGRR-TNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGD 400 G R T+++L ++ + R + +N + + A ++ + Sbjct: 368 RNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQELMAVSEHKLYWP 412 >4Q0C-A nrPDB Length = 584 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 45/117 (38%), Gaps = 21/117 (17%) Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476 P+ + + + +++ G + + G + + V + Sbjct: 351 APFTLFRTD-------EQFGGISAAVLQLLQLRTGLDFEIIGVDTVEE------------ 391 Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 533 ++ +L G AD+A L + RE + FS+P++ G+ +++ + P LD Sbjct: 392 LIAKLRSGEADMA-GALFVNSARESFLSFSRPYVRNGM-VIVTRQDPDAPVDADHLD 446 >2Q88-A nrPDB Length = 257 Score = 40.9 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 21/124 (16%) Query: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475 E P+ + + G ++A EI K +G + + S +YGA Sbjct: 22 EPPF-------TAVGADGKVSGAAPDVAREIFKRLGVAD--VVASISEYGA--------- 63 Query: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL--D 533 M+ L GR D A L + R + +S+P + + +KK + + + Sbjct: 64 -MIPGLQAGRHDAITAGLFMKPERCAAVAYSQPILCDAEAFALKKGNPLGLKSYKDIADN 122 Query: 534 PLAY 537 P A Sbjct: 123 PDAK 126 >4PX2-A nrPDB Length = 638 Score = 33.2 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 29/99 (29%), Gaps = 1/99 (1%) Query: 151 ADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLN 210 G Q V++T W+++ E L QDL+K +V Sbjct: 12 DMPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAE 71 Query: 211 AILGQIVKLEKNGIGYH-YILANLGFMDIDLNKFKESGA 248 + L Y IL + + + + + Sbjct: 72 IFQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPD 110 >4DX0-A nrPDB Length = 243 Score = 32.8 bits (73), Expect = 0.72, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 2/84 (2%) Query: 630 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMK 689 Y A LA ER +E E +AK ++ T+E + ++ I W + Sbjct: 16 YMAKLAE--QAERYEEMVEFMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIIS 73 Query: 690 SAEPSVFVRTTEEGMIRVRKSKGK 713 S E R E+ + +++ +GK Sbjct: 74 SIEQKEESRGNEDHVSSIKEYRGK 97 >4V8M-A5 nrPDB Length = 220 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 22/43 (51%) Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRN 862 + + F + + + ++R + ++ + NE +RT TL +N Sbjct: 57 GLRLDTGNFAWGTEASAQRARILDVVYNATSNELVRTKTLVKN 99 >5XXU-I nrPDB Length = 205 Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 25/44 (56%) Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNS 863 A+ + + + S+ +K+ + ++ S NE +RT+TL +NS Sbjct: 57 ALRLDTGNYSWSSQKIAKKTRLLGVVYNASNNELVRTNTLVKNS 100 >5OPT-Z nrPDB Length = 221 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 22/43 (51%) Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRN 862 + + F + + + ++R + ++ + NE +RT TL +N Sbjct: 57 GLRLDTGNFAWSTEAIAQRARILDVVYNATSNELVRTKTLVKN 99 >3AXY-C nrPDB Length = 240 Score = 30.9 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 2/84 (2%) Query: 630 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMK 689 Y A LA ER +E E +AK ++ T+E + ++ I W + Sbjct: 13 YMAKLAE--QAERYEEMVEYMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIVS 70 Query: 690 SAEPSVFVRTTEEGMIRVRKSKGK 713 S E R EE + +++ +GK Sbjct: 71 SIEQKEEGRGNEEHVTLIKEYRGK 94 >3IP9-A nrPDB Length = 356 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 47/322 (14%), Positives = 93/322 (28%), Gaps = 44/322 (13%) Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF--PVDTS-- 118 ++SD + + GV + G + + + ITP+ PV T Sbjct: 51 DVSDPKQGISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERG 110 Query: 119 --NQFVLQLRPELQEALIS--IIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTA 174 N F R + Q + + DH+K I+D L AA VT Sbjct: 111 LWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAA-NAAGVTE 169 Query: 175 VNI--LTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILAN 232 V + ++ + L +++ ++ I+ Q Sbjct: 170 VMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAK-------- 221 Query: 233 LGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSAL 292 L D ++ A++ G + +T + + + + P+ + Sbjct: 222 LVSGDGIVSN---ELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLY 278 Query: 293 TYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGN 352 +Y M + + + + AL++ F G Sbjct: 279 SY---AAMQAIAGAAKAAGSVEPEK-------------------VAEALKKGSFPTALGE 316 Query: 353 VQFNEKGRRTNYTLHVIEMKHD 374 + F+EKG + E K Sbjct: 317 ISFDEKGDPKLPGYVMYEWKKG 338 >4V6W-AI nrPDB Length = 208 Score = 30.1 bits (66), Expect = 4.9, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 23/44 (52%) Query: 820 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNS 863 A+ + F + S +++ + ++ S NE +RT TL +NS Sbjct: 57 ALRLETGNFAWASEGVARKTRIADVVYNASNNELVRTKTLVKNS 100 >2F6U-A nrPDB Length = 234 Score = 29.7 bits (65), Expect = 5.5, Method: Composition-based stats. Identities = 16/135 (11%), Positives = 41/135 (30%), Gaps = 10/135 (7%) Query: 138 DHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQ-VTAVNILTTTEEGYRMLFQDLEKKK 196 H +W+ + +I D + ++ A+ V T E R L + + + Sbjct: 2 SHMRWRKWRHITKLDPDRTNTDEIIKAVADSGTDAVMISGTQNVTYEKARTLIEKVSQYG 61 Query: 197 ERLVVVDCESERLNA---------ILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESG 247 +VV + + +L G ++ + + + Sbjct: 62 LPIVVEPSDPSNVVYDVDYLFVPTVLNSADGDWITGKHAQWVRMHYENLQKFTEIIESEF 121 Query: 248 ANVTGFQLVNYTDTI 262 + G+ ++N + Sbjct: 122 IQIEGYIVLNPDSAV 136 >5A5X-A nrPDB Length = 453 Score = 29.0 bits (63), Expect = 8.6, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 14/105 (13%) Query: 429 FEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGEL-VYGRAD 487 F+ + G+ ELA A+ +G ++E + + + +L G Sbjct: 20 FQDRNGETGFEYELAKRFAERLGVELKIETADNL------------DDLYAQLSREGGPA 67 Query: 488 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 532 +A A LT + + +S ++ + I+ + Q +P L Sbjct: 68 LAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQ-QRPTRPEDL 111 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.125 0.321 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,151,175 Number of Sequences: 36641 Number of extensions: 1138745 Number of successful extensions: 3891 Number of sequences better than 10.0: 92 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 3263 Number of HSP's gapped (non-prelim): 261 length of query: 907 length of database: 10,336,785 effective HSP length: 106 effective length of query: 801 effective length of database: 6,452,839 effective search space: 5168724039 effective search space used: 5168724039 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)