BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23381 (471 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1R6T-A nrPDB 967 0.0 5UJI-A nrPDB 781 0.0 3HV0-A nrPDB 473 e-134 3KT6-A nrPDB 460 e-130 3I05-A nrPDB 451 e-127 4J75-A nrPDB 403 e-112 3TZE-A nrPDB 375 e-104 3FOC-A nrPDB 357 9e-99 3JXE-A nrPDB 312 3e-85 3HZR-A nrPDB 250 7e-67 3A04-A nrPDB 139 2e-33 2CYB-A nrPDB 64 1e-10 2CYA-A nrPDB 61 1e-09 1YID-B nrPDB 60 2e-09 2J5B-A nrPDB 58 8e-09 3P0I-A nrPDB 54 1e-07 2DLC-X nrPDB 52 8e-07 6NCR-A nrPDB 51 1e-06 3VGJ-A nrPDB 50 1e-06 2CYC-A nrPDB 47 2e-05 2G36-A nrPDB 45 7e-05 1JIJ-A nrPDB 45 7e-05 5DK4-A nrPDB 45 1e-04 6OTJ-A nrPDB 43 3e-04 2JAN-A nrPDB 39 0.004 3PRH-A nrPDB 38 0.010 6HB6-A nrPDB 37 0.015 2DJV-A nrPDB 37 0.015 5IJX-A nrPDB 37 0.016 1X8X-A nrPDB 37 0.021 4OUD-B nrPDB 37 0.024 5IHX-A nrPDB 36 0.028 3SZ3-A nrPDB 32 0.54 3JB9-c nrPDB 32 0.87 1LXM-A nrPDB 31 0.96 2YY5-A nrPDB 31 1.1 3TS1-A nrPDB 31 1.2 1TYB-E nrPDB 31 1.4 2RKJ-A nrPDB 30 2.4 6DFU-A nrPDB 30 2.6 6MTK-A nrPDB 30 3.2 2EBS-A nrPDB 29 4.8 6N0W-A nrPDB 28 7.5 5V0I-A nrPDB 28 9.3 >1R6T-A nrPDB Length = 477 Score = 967 bits (2500), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/467 (99%), Positives = 465/467 (99%) Query: 1 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA Sbjct: 1 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 Query: 61 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 120 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI Sbjct: 61 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 120 Query: 121 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 180 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT Sbjct: 121 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 180 Query: 181 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 240 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAY AVENAKDIIACGFDINKTFIFSDLDY Sbjct: 181 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYGDAVENAKDIIACGFDINKTFIFSDLDY 240 Query: 241 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 300 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR Sbjct: 241 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 300 Query: 301 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 360 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF Sbjct: 301 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 360 Query: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 420 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY Sbjct: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 420 Query: 421 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLS 467 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL+ Sbjct: 421 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLA 467 >5UJI-A nrPDB Length = 388 Score = 781 bits (2017), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/375 (99%), Positives = 374/375 (99%) Query: 97 GIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPF 156 GIDYDKLIVRFGSSKIDKELINRIERATGQRPH FLRRGIFFSHRDMNQVLDAYENKKPF Sbjct: 1 GIDYDKLIVRFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQVLDAYENKKPF 60 Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV Sbjct: 61 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 120 Query: 217 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG 276 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG Sbjct: 121 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG 180 Query: 277 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH 336 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH Sbjct: 181 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH 240 Query: 337 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV 396 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV Sbjct: 241 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV 300 Query: 397 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI 456 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI Sbjct: 301 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI 360 Query: 457 VKEFMTPRKLSFDFQ 471 VKEFMTPRKLSFDFQ Sbjct: 361 VKEFMTPRKLSFDFQ 375 >3HV0-A nrPDB Length = 393 Score = 473 bits (1218), Expect = e-134, Method: Compositional matrix adjust. Identities = 217/375 (57%), Positives = 289/375 (77%), Gaps = 4/375 (1%) Query: 87 PWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQV 146 PW V+ +A GIDY+KLI +FG I K++I R+ER TGQ+ HHF RR IF SHRD ++ Sbjct: 6 PWEVKADNAYGIDYNKLIDKFGCKLITKDMIERMERLTGQKAHHFFRRNIFLSHRDFEKI 65 Query: 147 LDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK-D 205 LD YE + FYLYTGRGPSSE++HVGHL+PF+FTK+LQD F VPLVIQ+TDDEK+++K + Sbjct: 66 LDVYEKGELFYLYTGRGPSSESLHVGHLVPFLFTKYLQDTFKVPLVIQLTDDEKFIFKSN 125 Query: 206 LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKG 265 LTL++ ++YA EN KDIIACGFD TFIF++L+Y+ + Y ++++I+K ++ +Q+K Sbjct: 126 LTLEETHNYAYENMKDIIACGFDPELTFIFTNLEYI---AELYPDILRIEKKISCSQIKS 182 Query: 266 IFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAP 325 IFGF DS +GK +FPA+QAAP+FS+SFP IF RTDI CL+P AIDQDPYFRM RDVAP Sbjct: 183 IFGFKDSCNVGKFAFPAVQAAPAFSSSFPHIFGGRTDIHCLVPHAIDQDPYFRMVRDVAP 242 Query: 326 RIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIE 385 R+GY KP+ +HS F P+LQG+QTKMSAS NSSIF+ D + I+ K+ K+AFSGG+ T E Sbjct: 243 RLGYLKPSSIHSIFLPSLQGSQTKMSASVQNSSIFVNDNEESIRNKIMKYAFSGGQATEE 302 Query: 386 EHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEH 445 E R+ G N DVDVS+ YL F +EDD+KLE+I K Y+SG ML+GE+K L++ L L H Sbjct: 303 EQRRLGANLDVDVSWQYLRFLMEDDEKLEEIGKKYSSGEMLSGEIKSILVQELVKLTKNH 362 Query: 446 QARRKEVTDEIVKEF 460 Q R+ + D+++ +F Sbjct: 363 QKNREAINDDVIAKF 377 >3KT6-A nrPDB Length = 438 Score = 460 bits (1184), Expect = e-130, Method: Compositional matrix adjust. Identities = 217/396 (54%), Positives = 290/396 (73%), Gaps = 8/396 (2%) Query: 77 ATEAEEDFVDPWTVQ-----TSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHF 131 +T+ +E V PW V+ A+ IDYDKLI +FG+ +++E + R ++ TG+ PHHF Sbjct: 19 STDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKRFKQVTGREPHHF 78 Query: 132 LRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPL 191 LR+G+FFS RD ++LD YE KPF+LYTGRGPSS++MH+GH+IPF+FTKWLQ+VF+VPL Sbjct: 79 LRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQEVFDVPL 138 Query: 192 VIQMTDDEKYLWK-DLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKN 250 VI++TDDEK+L+K LT++ ++A ENAKDIIA GFD TFIFSDL YMG FY+ Sbjct: 139 VIELTDDEKFLFKHKLTINDVKNFARENAKDIIAVGFDPKNTFIFSDLQYMG--GAFYET 196 Query: 251 VVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCA 310 VV++ + +T + K +FGF DSDCIGK F +IQ A +F +SFP + CLIPCA Sbjct: 197 VVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCA 256 Query: 311 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370 IDQDPYFR+ RDVA ++ Y KPALLHS FFPALQG+ TKMSASD ++IF+TDT KQI+ Sbjct: 257 IDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQK 316 Query: 371 KVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGEL 430 K+NK+AFSGG+ + + HR+ GGN DVDV++ YL+FF +DD L++ Y SG +L+GE+ Sbjct: 317 KINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKYKSGELLSGEM 376 Query: 431 KKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 KK IE LQ + Q RR +V +E + +FM P KL Sbjct: 377 KKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKL 412 >3I05-A nrPDB Length = 395 Score = 451 bits (1159), Expect = e-127, Method: Compositional matrix adjust. Identities = 217/384 (56%), Positives = 279/384 (72%), Gaps = 9/384 (2%) Query: 82 EDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHR 141 E V PW+V+ ++YDKLI FGS ID+ L+ RIER G++PHHFLRRGIFFSHR Sbjct: 9 EAVVTPWSVEGD----VNYDKLIKDFGSHAIDEALLERIERVLGKKPHHFLRRGIFFSHR 64 Query: 142 DMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKY 201 D+N +LD YE+ +PFYLYTGRGPSSE+MH+GHLIPF+FTKWLQD F VPLVIQMTDDEK+ Sbjct: 65 DLNLLLDVYESGQPFYLYTGRGPSSESMHMGHLIPFMFTKWLQDSFRVPLVIQMTDDEKF 124 Query: 202 LWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFN 261 ++++ ++Q + EN KDIIA GFD TFIF D DYMG Y+ V KI++ T + Sbjct: 125 YFRNIPMEQVEAMTTENIKDIIAMGFDPELTFIFRDFDYMGC---MYRTVAKIERAFTAS 181 Query: 262 QVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIF-RDRTDIQCLIPCAIDQDPYFRMT 320 QV+G FGF D G+ FPAIQAAPSFS +FP IF ++ CLIP AIDQDPYFR+T Sbjct: 182 QVRGCFGFAMEDNCGRWMFPAIQAAPSFSAAFPHIFPPSMGNVFCLIPQAIDQDPYFRLT 241 Query: 321 RDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGG 380 RD+APR+GY KPA++HS FFP L G + KMS+S +++ LTDT K +K K+NKHAFSGG Sbjct: 242 RDIAPRLGYLKPAVIHSKFFPGLSGPKGKMSSSS-GTAVLLTDTEKMVKDKINKHAFSGG 300 Query: 381 RDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQP 440 T +EH G N +VDV +L+FFLEDD++L +++K+Y G ++TGE+KK LI + Sbjct: 301 GATKQEHFLLGANVEVDVPIQWLSFFLEDDEELARVKKEYMLGRIMTGEVKKLLINTITA 360 Query: 441 LIAEHQARRKEVTDEIVKEFMTPR 464 + HQ +RK VTDE V+ F + R Sbjct: 361 ITKTHQEKRKLVTDEDVQLFTSTR 384 >4J75-A nrPDB Length = 409 Score = 403 bits (1035), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/400 (49%), Positives = 264/400 (66%), Gaps = 21/400 (5%) Query: 85 VDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMN 144 V PW V ++ +GI+Y+KLI FG SKI + I RIE+ T + HHF+RRGIFFSHRD++ Sbjct: 9 VTPWDVNINNEEGINYNKLIKEFGCSKITENHIKRIEKLTNSKAHHFIRRGIFFSHRDLD 68 Query: 145 QVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLW- 203 +L+ YE K FY+YTGRGPSS +MH+GHLIPF F K+LQ+ FNVPLVIQ++DDEKYL+ Sbjct: 69 FLLNYYEQHKCFYIYTGRGPSSLSMHLGHLIPFYFCKYLQEAFNVPLVIQLSDDEKYLFN 128 Query: 204 KDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQV 263 ++ +L+ + EN KDII+ G + TFIF + +Y G Y V+ I K T NQ Sbjct: 129 QNYSLEYINTLTNENVKDIISVGLNPELTFIFKNTEYAGY---LYPTVLSIHKKTTLNQS 185 Query: 264 KGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDV 323 +FGF SD IGKIS+P+ Q AP FS FP +I CL+P IDQDPYFR++RD+ Sbjct: 186 MNVFGFNHSDNIGKISYPSFQIAPCFSQCFPNFL--GKNIPCLVPQGIDQDPYFRLSRDI 243 Query: 324 APRIGYPKPALLHSTFFPALQG---------------AQTKMSASDPNSSIFLTDTAKQI 368 A ++ KP ++HS F P LQG ++ + NS IFLTDT +QI Sbjct: 244 AVKMALHKPVVVHSVFMPGLQGVNSKMSSTKKKKDDNGKSNSTFDHNNSVIFLTDTPEQI 303 Query: 369 KTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTG 428 K K+NK+AFSGG TI+EHR+ GGN D D+S+ YL + LEDD+KL +I + Y G ML+G Sbjct: 304 KNKINKYAFSGGGTTIQEHREKGGNLDKDISYQYLRYLLEDDNKLNEIGEKYKKGEMLSG 363 Query: 429 ELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSF 468 E+KK LI+VL L+ +HQ ++K +TDE + F P K S Sbjct: 364 EIKKILIDVLTELVLKHQEKKKSLTDEEISYFFDPNKPSL 403 >3TZE-A nrPDB Length = 406 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 179/389 (46%), Positives = 256/389 (65%), Gaps = 10/389 (2%) Query: 82 EDFVDPWTVQTSSAK----GIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIF 137 E + PW V+ S IDYDK+I +FG K ++ L +R+E+ +G+ H+F RRGI Sbjct: 24 EQRITPWDVEVVSTDEVPVAIDYDKIINQFGCEKFNQALADRLEKLSGKPAHYFFRRGIV 83 Query: 138 FSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTD 197 F+HRD N +LD N +PFYLYTGRGPSS+ MH+GH IPF+ K++QD F + LVIQ+TD Sbjct: 84 FAHRDFNLLLDEIANNRPFYLYTGRGPSSKTMHIGHTIPFLLCKYMQDAFKIRLVIQITD 143 Query: 198 DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKH 257 DEK+LWK + L+ A +Y EN KDI+ GFD T+IFS+++ S F +N++KI K Sbjct: 144 DEKFLWKSMRLEDAMAYGRENIKDIVTLGFDPKLTYIFSNVE---ASHHFEENILKISKT 200 Query: 258 VTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYF 317 + N+ +FGF S IG++ FPA + AP FS+SF I + CL+P A+DQDP+F Sbjct: 201 INLNEAIKVFGFDMSSNIGQVGFPAKEIAPCFSSSFRFIGK---GAMCLVPAAVDQDPFF 257 Query: 318 RMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAF 377 R+ RD A +G KP+ ++ + P L+G KMSASDPNSSI+L D I+ K+ +A+ Sbjct: 258 RLARDKAKALGEKKPSSIYVSLLPDLKGVNRKMSASDPNSSIYLDDAQDTIRKKIIAYAY 317 Query: 378 SGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV 437 SGGR T+EEHR+ GG+ DVDV F YL +FL+DD +LE+ R Y G + + E+K+ + V Sbjct: 318 SGGRKTLEEHREKGGDIDVDVPFEYLKYFLDDDQELEKYRSGYIKGEITSKEMKEKCVVV 377 Query: 438 LQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 +Q ++ +Q RK VTD+ ++ F+ K Sbjct: 378 IQEFVSRYQESRKRVTDDDLRAFIDINKF 406 >3FOC-A nrPDB Length = 451 Score = 357 bits (915), Expect = 9e-99, Method: Compositional matrix adjust. Identities = 182/413 (44%), Positives = 250/413 (60%), Gaps = 50/413 (12%) Query: 103 LIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGR 162 +I RFG++ I +L+ R E TG + H LRRG+F++HRD + L YE P Y+YTGR Sbjct: 39 IITRFGAAPITDDLLKRFETVTGTKAHPMLRRGLFYAHRDFEEFLSYYEKGHPIYIYTGR 98 Query: 163 GPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLW-KDLTLDQAYSYAVENAKD 221 GPSS A+H+GHL+PFIFTK+LQD F +VIQ+TDDEK+L + L+ + SY EN KD Sbjct: 99 GPSSGALHLGHLLPFIFTKYLQDAFKCYVVIQITDDEKFLRNRSLSYAEVDSYTRENIKD 158 Query: 222 IIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFP 281 IIACGFD +KTFIF + Y+ + + Y+ + + + +Q++ FGF++ +G +FP Sbjct: 159 IIACGFDPDKTFIFINSQYLSLKNR-YRFSCLVDRMLPISQLRASFGFSNDANVGYAAFP 217 Query: 282 AIQAAPSFSNSF---------------------------------------------PQI 296 Q P +S F ++ Sbjct: 218 PKQMLPVYSTYFDGLPFTRVPLPVGTGNEDAADAVSTKKASKKTPKKDAVLSPVHVVEEL 277 Query: 297 FRDRTDIQ---CLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSAS 353 F D Q CLI I+QDPYFR+ RD+APR+G+PK A L F P LQG+ TKMSAS Sbjct: 278 FPDSKRYQKAMCLIASGIEQDPYFRLARDLAPRMGHPKNAYLLGKFLPGLQGSGTKMSAS 337 Query: 354 DPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKL 413 DPNS+I+LTDT QIK K+N++AFSGGRDT EEHR FG + VDVS YL F++DD +L Sbjct: 338 DPNSAIYLTDTPAQIKNKINRYAFSGGRDTEEEHRAFGADLSVDVSVRYLEVFMKDDAEL 397 Query: 414 EQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 E+++ DY +G +LTGE+K LI +LQ LI EH RR +V +++ F ++L Sbjct: 398 EKLKADYKTGKLLTGEVKATLIGILQGLIKEHAERRDKVDTTMIESFTVKKEL 450 >3JXE-A nrPDB Length = 392 Score = 312 bits (799), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 174/390 (44%), Positives = 238/390 (61%), Gaps = 22/390 (5%) Query: 80 AEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFS 139 EE V PW V+ +DYDKLI FG+S + ++L+ + T F RR FFS Sbjct: 2 VEEFKVTPWEVEGV----VDYDKLIKHFGTSPLTEDLLEKTAELTKSELPIFFRRKFFFS 57 Query: 140 HRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDE 199 HRD + +L YE + F+LYTGRGPS MH+GH+IPF TKWLQ+ F V L IQ+TDDE Sbjct: 58 HRDYDLILKDYEEGRGFFLYTGRGPSG-PMHIGHIIPFFATKWLQEKFGVNLYIQITDDE 116 Query: 200 KYLWKD-LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHV 258 K+L+K+ LT D +A +N DIIA GFD +KTFIF + ++ + Y+ + I K + Sbjct: 117 KFLFKENLTFDDTKRWAYDNILDIIAVGFDPDKTFIFQNSEFTKI----YEMAIPIAKKI 172 Query: 259 TFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFR 318 F+ K +FGFT+ IG I FPAIQ AP+F R R CLIP AIDQDPY+R Sbjct: 173 NFSMAKAVFGFTEQSKIGMIFFPAIQIAPTFFE------RKR----CLIPAAIDQDPYWR 222 Query: 319 MTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFS 378 + RD A +GY K A LHS F P+L KMSAS P ++I+LTD+ + ++ KV K + Sbjct: 223 LQRDFAESLGYYKTAALHSKFVPSLTSLSGKMSASKPETAIYLTDSPEDVEKKVWKFTLT 282 Query: 379 GGRDTIEEHRQFGGNCDVDVSFMYL-TFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV 437 GGR T++E R+ GG + V F +L FF EDD KL++ +G + GE K+ LI Sbjct: 283 GGRPTLKEQREKGGEPEKCVVFKWLEIFFEEDDKKLKERYYACKNGELTCGECKRYLISK 342 Query: 438 LQPLIAEHQARRKEVTDEIVKEFMTPRKLS 467 +Q + EHQ RRK+ +++V++F KL+ Sbjct: 343 IQEFLKEHQRRRKKA-EKLVEKFKYTGKLA 371 >3HZR-A nrPDB Length = 386 Score = 250 bits (639), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 128/377 (33%), Positives = 221/377 (58%), Gaps = 7/377 (1%) Query: 90 VQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDA 149 +Q+ + + DY++LI G + I + I RIE+ +G+ PHH+L RG+F + + +++ LD Sbjct: 17 LQSFTTRTTDYNQLINSVGINAITPQQIQRIEKLSGKAPHHYLSRGVFLAEKSLDKFLDD 76 Query: 150 YENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLD 209 E KKP +++ + P E + + I F ++LQD FN+ ++IQ+ DD K L ++ T++ Sbjct: 77 VEAKKPTFIFIQKYPQKE-VALEEYITLEFARYLQDAFNIQVIIQILDDIKVLNREATIN 135 Query: 210 QAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGF 269 +A + + K I+A GF+ +KTFI++D Y G Y+ + ++K +N V+ F F Sbjct: 136 EASKMSNDLMKYILAFGFNEDKTFIYTDYQYFG---KMYRTISLVEKATAYNVVQPFFNF 192 Query: 270 TDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGY 329 SD IGK++ P+I A FS S+ F + +CL+ +I + + +A + + Sbjct: 193 EYSDNIGKLASPSIMTASMFSQSYSHFFS--SPARCLVLDSIKNVQFHSIIDQIATTLNF 250 Query: 330 PKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQ 389 +P +L P L G TK ++SI L+D AKQ++ K+NK AFSGGR+T EEH++ Sbjct: 251 IQPTVLFHKMVPLLSGV-TKFDIPSDHNSILLSDNAKQVERKINKLAFSGGRNTTEEHKK 309 Query: 390 FGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARR 449 GG CD+DVSF L F D+ +++ + + Y+ G +L+GELKK + ++ I + A++ Sbjct: 310 LGGQCDIDVSFQLLNIFSSDNAQVKDVEEKYSKGELLSGELKKIVSASMKDFIVAYDAKK 369 Query: 450 KEVTDEIVKEFMTPRKL 466 K +T +K +++ K Sbjct: 370 KPITTAYLKAYISKTKF 386 >3A04-A nrPDB Length = 372 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 111/372 (29%), Positives = 181/372 (48%), Gaps = 30/372 (8%) Query: 85 VDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMN 144 +DPW + + DYD+L+ FG + L + R G P +RRGI F HRD + Sbjct: 6 LDPW----GAVEIKDYDRLLRTFGIRPFSEVL--PLLRKAGMEPSFLMRRGIIFGHRDFD 59 Query: 145 QVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQ-DVFNVPLVIQMTDDEKYLW 203 ++L+A + + TG PS + H GH + +LQ + F V + + D E + Sbjct: 60 KILEAKARGERVAVLTGFMPSGK-FHFGHKLTVDQLIYLQKNGFKV--FVAIADAEAFAV 116 Query: 204 KDLTLDQAYSYAVEN-AKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQ 262 + + ++A AVE ++IA G D T + + + +++ + VT + Sbjct: 117 RRIGREEAVRIAVEEYIANMIALGLDPKDTEFYFQTN---RGTPYFRLIQLFSGKVTAAE 173 Query: 263 VKGIFG-FTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTR 321 ++ I+G T + + ++ QAA + R ++P DQDP+ R+TR Sbjct: 174 MEAIYGELTPAKMMASLT----QAADILHVQLDEYGGYR---HVVVPVGADQDPHLRLTR 226 Query: 322 DVAPRIG----YPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAF 377 D+A R+ +PA + P L G KMS+S P+S+IFLTD + + K+ + A Sbjct: 227 DLADRMAGVVELERPASTYHKLQPGLDG--RKMSSSRPDSTIFLTDPPEVARNKLFR-AL 283 Query: 378 SGGRDTIEEHRQFGGNCDV-DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIE 436 +GGR T EE R+ GG +V V M L + DD +++ I G +L GE K+ E Sbjct: 284 TGGRATAEEQRRLGGVPEVCSVYHMDLYHLMPDDGEVKHIYTSCRLGKILCGECKQIAWE 343 Query: 437 VLQPLIAEHQAR 448 L+ +AEHQ+R Sbjct: 344 KLERFLAEHQSR 355 >2CYB-A nrPDB Length = 323 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 74/334 (22%), Positives = 142/334 (42%), Gaps = 58/334 (17%) Query: 139 SHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDD 198 + ++ Q+++ E + Y G PS E +H+GH++ LQ+ +++ + D Sbjct: 19 TEEELRQLIETKEKPRA---YVGYEPSGE-IHLGHMMTVQKLMDLQEA-GFEIIVLLADI 73 Query: 199 EKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHV 258 YL + T ++ A N K IA G D ++ +Y +S + +V+K+ + Sbjct: 74 HAYLNEKGTFEEIAEVADYNKKVFIALGLDESRAKFVLGSEYQ-LSRDYVLDVLKMARIT 132 Query: 259 TFNQVK----GIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQD 314 T N+ + + + + ++ +P +QA I D+ IDQ Sbjct: 133 TLNRARRSMDEVSRRKEDPMVSQMIYPLMQAL--------DIAHLGVDLAV---GGIDQR 181 Query: 315 PYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNK 374 + R+ PR+GY P LH+ L G KMS+S N I + D ++++ K+ K Sbjct: 182 KIHMLARENLPRLGYSSPVCLHTPILVGLDG--QKMSSSKGN-YISVRDPPEEVERKIRK 238 Query: 375 -HAFSG-------------------GRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLE 414 + +G G+ +E +FGG+ + Y +F E Sbjct: 239 AYCPAGVVEENPILDIAKYHILPRFGKIVVERDAKFGGDVE------YASF--------E 284 Query: 415 QIRKDYTSGAMLTGELKKALIEVLQPLIAEHQAR 448 ++ +D+ SG + +LK A+ + L L+ + + R Sbjct: 285 ELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARKR 318 >2CYA-A nrPDB Length = 364 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 77/326 (23%), Positives = 130/326 (39%), Gaps = 66/326 (20%) Query: 159 YTGRGPSSEAMHVGHLIPFIFTKWLQDV---FNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 Y G PS A H+G L+ K L + F+V L D+ L +A + Sbjct: 39 YIGYEPSGVA-HIGWLVWMYKVKDLVEAGVDFSVLEATWHAYINDKLGGDMDLIRAAARI 97 Query: 216 VENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVK---GIFGFTDS 272 V + A G + + F D + + ++ V+++ K + +V+ I G Sbjct: 98 VRRVME--AAGVPVERVR-FVDAEELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAE 154 Query: 273 DC---IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGY 329 + K+ +P +Q + IF DI +DQ + RDVA ++G Sbjct: 155 EAEVDASKLIYPLMQVS--------DIFYMDLDIAL---GGMDQRKAHMLARDVAEKLGR 203 Query: 330 PKPALLHSTFFPALQG---------------AQTKMSASDPNSSIFLTDTAKQIKTKVNK 374 KP +H+ +LQG A+ KMS S P +++F+ D+ I+ K+ K Sbjct: 204 KKPVAIHTPIISSLQGPGRMEASQGEIDDVLAEVKMSKSKPETAVFVVDSDDDIRRKIRK 263 Query: 375 HAFSGGRDTIEEHRQFGGNCDVDVSFMYL----TFFLEDD-----------DKLEQIRKD 419 +Q GN ++++ L F L D E++ +D Sbjct: 264 AYCPA--------KQVQGNPVLEIARYILFARDGFTLRVDRPAKYGGPVEYTSYEELERD 315 Query: 420 YTSGAMLTGELKKA----LIEVLQPL 441 YT G + +LK A LIEV++P+ Sbjct: 316 YTDGRLHPLDLKNAVAESLIEVVRPI 341 >1YID-B nrPDB Length = 351 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 78/310 (25%), Positives = 128/310 (41%), Gaps = 38/310 (12%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKW-LQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 + TG P+ A+H+GHL + + LQD L + + D + +Q + Sbjct: 25 VLTGDRPTG-ALHLGHLAGSLQNRVRLQD--EAELFVLLADVQALTDHFDRPEQVRENVL 81 Query: 217 ENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIF---GFTD 271 A D +A G D KT + S + + + ++ N+V + VK G+ + Sbjct: 82 AVALDYLAAGLDPQKTTCVVQSAVPELAELTVYFLNLVTVSHLRQNPTVKAEIAQKGYGE 141 Query: 272 SDCIGKISFPAIQAA--PSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDV------ 323 G +P QAA +F + L+P DQ P TR++ Sbjct: 142 RVPAGFFVYPVSQAADIAAFGAT-------------LVPVGDDQLPMLEQTREIVRRFNA 188 Query: 324 --APRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGR 381 AP + P+ L P L G Q KMS S N +I L D+A ++ KV G Sbjct: 189 LYAPVLAEPQAQLSRVPRLPGLDG-QAKMSKSLGN-AIALGDSADEVARKVMGMYTDPGH 246 Query: 382 DTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPL 441 + + GN F +L F D +++ ++ Y +G + ++KK LI+VL + Sbjct: 247 LRASDPGRVEGNP----VFTFLDAFDPDPARVQALKDQYRAGGLGDVKVKKHLIDVLNGV 302 Query: 442 IAEHQARRKE 451 +A + RR E Sbjct: 303 LAPIRTRRAE 312 >2J5B-A nrPDB Length = 348 Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 13/156 (8%) Query: 224 ACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVK---GIFGFTDSDCI--GKI 278 ACG +++ T +++ + + + ++ I + T ++VK I G +SDC+ +I Sbjct: 110 ACGINLDGTRFIWASEFIASNPSYIERMLDIAEFSTISRVKRCCQIMGRNESDCLKASQI 169 Query: 279 SFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHST 338 +P +QAA F ++ + DI L IDQ + + A G P L Sbjct: 170 FYPCMQAADVF-----ELVPEGIDICQL---GIDQRKVNMLAIEYANDRGLKIPISLSHH 221 Query: 339 FFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNK 374 +L G + KMS SDP +IF+ DT +++ K+++ Sbjct: 222 MLMSLSGPKKKMSKSDPQGAIFMDDTEQEVSEKISR 257 >3P0I-A nrPDB Length = 690 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 17/157 (10%) Query: 224 ACGFDINKT-FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVK---GIFGFTDSDCIG-KI 278 A G D++K F++S + + +++ V+ I + T ++K I G T+ ++ Sbjct: 110 AAGMDMDKVLFLWSSEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEGTLTAAQV 169 Query: 279 SFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYP-KPALLHS 337 +P +Q IF + DI L +DQ + R+ IG KP +L Sbjct: 170 LYPLMQCC--------DIFFLKADICQL---GLDQRKVNMLAREYCDLIGRKLKPVILSH 218 Query: 338 TFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNK 374 L+ Q KMS SDP+S+IF+ DT + + K+ + Sbjct: 219 HMLAGLKQGQAKMSKSDPDSAIFMEDTEEDVARKIRQ 255 >2DLC-X nrPDB Length = 394 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Query: 302 DIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPAL-QGAQTKMSASDPNSSIF 360 D+ C +DQ F + + P +GY K A L + P L QG KMSASDPNS I Sbjct: 182 DVDCQF-GGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG--KMSASDPNSKID 238 Query: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEH 387 L + KQ+K K+N S G +EE+ Sbjct: 239 LLEEPKQVKKKINSAFCSPG--NVEEN 263 >6NCR-A nrPDB Length = 354 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 72/333 (21%), Positives = 135/333 (40%), Gaps = 75/333 (22%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKY----LWKDL------- 206 + TG P+ + +H+GH W+ + N +Q+ +D +Y + DL Sbjct: 14 VLTGDRPTGK-LHLGH--------WIGSIMNR---LQLQNDSRYDCFFIIADLHTLTTKT 61 Query: 207 ---TLDQAYSYAVENAKDIIACGFDINKT---------------FIFSDLDYMGMSSGFY 248 + Q ++ + D ++ G D K+ IFS L + G Sbjct: 62 RKEEILQIDNHIYDVLADWLSVGIDPEKSAIYLQSAIPEIYELNLIFSMLTPLNHIMGI- 120 Query: 249 KNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIP 308 ++ ++ ++ + N+ +S G I +P +Q+A I + L+P Sbjct: 121 PSIKEMARNASLNE--------ESLSHGLIGYPVLQSA--------DILLAKAH---LVP 161 Query: 309 CAIDQDPYFRMTRDVAPRIG------YPKPALLHSTFFPALQG--AQTKMSASDPNSSIF 360 D + + +TRD+A +P+P +L AL G Q KMS S N++I+ Sbjct: 162 VGKDNEAHVELTRDIAKTFNRLYGEVFPEPDILQGEL-TALVGTNGQGKMSKS-ANNAIY 219 Query: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 420 L+D AK ++ K+ K R H G + + F+Y F +++E+ + Y Sbjct: 220 LSDDAKTVQEKIRKLYTDPNRI----HATTPGRVEGNPLFIYHDLFNPHKEEVEEFKTRY 275 Query: 421 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVT 453 G + E+K L E + + + +R E+ Sbjct: 276 RQGCIRDVEVKARLAEEINLFLNPFREKRSELV 308 >3VGJ-A nrPDB Length = 373 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 101/242 (41%), Gaps = 43/242 (17%) Query: 153 KKPFYLYTGRGPSSEAMHV--GHLIPFIFTK----------WLQDVFNVPLVIQMTDDEK 200 K+ Y G PS MH+ G L I K W+ D F L +M+ D K Sbjct: 54 KRKLICYDGFEPSGR-MHIAQGLLKSIIVNKLTSNGCTFIFWIADWF-AHLNNKMSGDLK 111 Query: 201 YLWKDLTLDQAYSYAVENAKDIIACGFDI-NKTFIFSDLDYMGMSSGFYKNVVKIQKHVT 259 + + SY +E K +CG ++ N F+++ + + ++ V+ I + Sbjct: 112 ------KIKKVGSYFIEVWK---SCGMNMENVQFLWASEEINKKPNEYWSLVLDISRSFN 162 Query: 260 FNQVK---GIFGFTDSD---CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQ 313 N++K I G ++ + C +I +P +Q A IF DI L IDQ Sbjct: 163 INRMKRCLKIMGRSEGEENYC-SQILYPCMQCA--------DIFFLNVDICQL---GIDQ 210 Query: 314 DPYFRMTRDVA-PRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKV 372 + R+ + KP +L P L Q KMS SD NS+IF+ D+ + K+ Sbjct: 211 RKVNMLAREYCDIKKIKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMDDSESDVNRKI 270 Query: 373 NK 374 K Sbjct: 271 KK 272 >2CYC-A nrPDB Length = 375 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/251 (22%), Positives = 97/251 (38%), Gaps = 82/251 (32%) Query: 247 FYKNVVKIQKHVTFNQVK---GIFGFTDSDCI--GKISFPAIQAAPSFSNSFPQIFRDRT 301 +++ V+ I K+VT ++V I G + I K+ +P +Q A F Sbjct: 130 YWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQGV-------- 181 Query: 302 DIQCLIPCAIDQDPYFRMTRDVAPRIGYP---------KPALLHSTFFPALQ-------- 344 + +DQ + +VA ++ Y KP +H LQ Sbjct: 182 ---TIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIE 238 Query: 345 --------GAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRD-------------- 382 AQ KMS S P S++F+ D+ ++I+ K+ K AF R+ Sbjct: 239 SEEEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRK-AFCPAREVRYNPVLDWVEYII 297 Query: 383 --------TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKA- 433 T+ +FGG+ Y TF E++++D+ G + +LK A Sbjct: 298 FREEPTEFTVHRPAKFGGDVT------YTTF--------EELKRDFAEGKLHPLDLKNAV 343 Query: 434 ---LIEVLQPL 441 LI +L+P+ Sbjct: 344 AEYLINLLEPI 354 >2G36-A nrPDB Length = 340 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 47/235 (20%), Positives = 98/235 (41%), Gaps = 42/235 (17%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYL----WKDLT-----L 208 + +G P+ + +H+GHL+ + W++ +Q +E + W LT + Sbjct: 15 ILSGMRPTGK-LHIGHLVGAL-ENWVK--------LQEEGNECFYFVADWHALTTHYDDV 64 Query: 209 DQAYSYAVENAKDIIACGFDINKTFIF-----SDLDYMGMSSGFYKNVVKIQKHVTFNQV 263 + Y + + +ACG D K+ IF + + + +V ++++ T+ ++ Sbjct: 65 SKLKEYTRDLVRGFLACGIDPEKSVIFVQSGVKEHAELALLFSMIVSVSRLERVPTYKEI 124 Query: 264 KGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDV 323 K + D G + +P +QAA I++ +P DQ + +TR++ Sbjct: 125 KSELNYKDLSTAGFLIYPVLQAADIL------IYKAEG-----VPVGEDQVYHIELTREI 173 Query: 324 APRIGY------PKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKV 372 A R Y P+P + S P L G + + + I L + K+++ + Sbjct: 174 ARRFNYLYDEVFPEPEAILSR-VPKLPGTDGRKMSKSYGNIINLEISEKELEQTI 227 >1JIJ-A nrPDB Length = 420 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 36/60 (60%), Gaps = 1/60 (1%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ + D + D NK+ LY G P+++++H+GHL+PF+ + Q+ + P+V+ Sbjct: 12 RGLIYQQTDEQGIEDLL-NKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVL 70 >5DK4-A nrPDB Length = 329 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 59/254 (23%), Positives = 104/254 (40%), Gaps = 34/254 (13%) Query: 223 IACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISF 280 +A G D + FI S++ ++ + +V I + Q K ++ G +++ Sbjct: 67 LAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQFKEKSAGKEAVSAGLLTY 126 Query: 281 PAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPKPALLHST 338 P + AA I TDI +P DQ + +TRD+A R Y + + Sbjct: 127 PPLMAA--------DILLYNTDI---VPVGEDQKQHIELTRDLAERFNKRYGELFTIPEA 175 Query: 339 FFPALQGAQT--------KMSASDPNSSIFLT--DTAKQIKTKVNKHAFSGGRDTIEEHR 388 P + GA+ KMS SDPN ++T D AK I+ K+ K A + TI Sbjct: 176 RIPKV-GARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKI-KSAVTDSEGTI---- 229 Query: 389 QFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSG--AMLTGELKKALIEVLQPLIAE-H 445 ++ +S + + +E++ + Y + +L + +IE L+P+ H Sbjct: 230 RYDKEAKPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYH 289 Query: 446 QARRKEVTDEIVKE 459 E D ++ E Sbjct: 290 HWMESEELDRVLDE 303 >6OTJ-A nrPDB Length = 439 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D+ + LDA N++ LY G P+++++H+GHL+P + + Q + P+ + Sbjct: 18 RGLIAQTTDI-EALDALLNEQKIALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIAL 76 >2JAN-A nrPDB Length = 432 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D++ L A + P +Y G P++ ++H GHL+P + + Q + P+V+ Sbjct: 12 RGLIAQSTDLD-TLAAEAQRGPMTVYAGFDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVL 70 >3PRH-A nrPDB Length = 388 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 52/238 (21%), Positives = 92/238 (38%), Gaps = 39/238 (16%) Query: 223 IACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISF 280 +A G D K FI S++ + + V I + Q K ++ G +++ Sbjct: 100 LAVGLDPEKATLFIQSEVPAHAQAGWMMQCVAYIGELERMTQFKDKSKGNEAVVSGLLTY 159 Query: 281 PAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVA-------------PRI 327 P + AA I TD L+P DQ + +TR++A P + Sbjct: 160 PPLMAA--------DILLYGTD---LVPPGEDQKQHLELTRNLAERFNKKYNDIFTIPEV 208 Query: 328 GYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLT--DTAKQIKTKVNKHAFSGGRDTIE 385 PK +L KMS SDPN ++T D KQ++ K+ K A + + Sbjct: 209 KIPKVG----ARIMSLNDPLKKMSKSDPNQKAYITLLDEPKQLEKKI-KSAVTDSEGIV- 262 Query: 386 EHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAM--LTGELKKALIEVLQPL 441 +F VS + + + + +E++ Y G+L + ++ L+P+ Sbjct: 263 ---KFDKENKPGVSNLLTIYSILGNTTIEELEAKYEGKGYGEFKGDLAEVVVNALKPI 317 >6HB6-A nrPDB Length = 424 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 24/39 (61%) Query: 155 PFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 P LY G P+++++H+GHL+P + K Q + P+ + Sbjct: 33 PIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVAL 71 >2DJV-A nrPDB Length = 79 Score = 37.4 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 31/57 (54%) Query: 4 SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 ++P + L + + QG +VR LKA A K+E+ + V L+ LK A G+ +A Sbjct: 10 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 66 >5IJX-A nrPDB Length = 384 Score = 37.4 bits (85), Expect = 0.016, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 25/49 (51%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKW 182 RG+ S LD +K Y G P++ ++H+GH++PF+ W Sbjct: 44 RGLVNSVVGQRDALDKLITRKRVGFYAGVDPTAPSLHIGHMLPFMILGW 92 >1X8X-A nrPDB Length = 322 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 24/39 (61%) Query: 155 PFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 P LY G P+++++H+GHL+P + K Q + P+ + Sbjct: 33 PIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVAL 71 >4OUD-B nrPDB Length = 394 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 23/39 (58%) Query: 155 PFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 P LY G P+++++H GHL+P + K Q + P+ + Sbjct: 34 PIALYCGFDPTADSLHAGHLVPLLCLKRFQQAGHKPVAL 72 >5IHX-A nrPDB Length = 395 Score = 36.2 bits (82), Expect = 0.028, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 130 HFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNV 189 H RG+ +L +K +Y G P++ +MHVGH++PF+ W V+ + Sbjct: 40 HLEERGLIHDVVGDRDLLHRVFTEKRVGIYAGVDPTAPSMHVGHMLPFMVLAW-GYVWGL 98 Query: 190 PLV 192 P+ Sbjct: 99 PVT 101 >3SZ3-A nrPDB Length = 341 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 71/166 (42%), Gaps = 28/166 (16%) Query: 307 IPCAIDQDPYFRMTRDVAPR---IGYPKPAL--LHSTFFP-------ALQGAQTKMSASD 354 +P DQ + + RD+A R I P+ + + + P +LQ A KMS SD Sbjct: 147 VPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSD 206 Query: 355 PN--SSIFLTDTAKQIKTKVNKH---AFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLED 409 N + I L + K I K+NK A + R + + G ++ + + Sbjct: 207 DNRKNVITLLEDPKSIIKKINKAQTDAETPPRIAYDVENKAG------IANLMGLYSAAT 260 Query: 410 DDKLEQIRKDYTSGAMLTGELKK----ALIEVLQPLIAEHQARRKE 451 +I Y +G + G KK A++ +L+P+ AE+Q R + Sbjct: 261 GKTFAEIEAQY-AGVEMYGPFKKDVGEAVVAMLEPVQAEYQRIRND 305 >3JB9-c nrPDB Length = 639 Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 10/67 (14%) Query: 187 FNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSG 246 F+ P + +M +EK L K Q Y YA + AKD KT+ ++LDY+ ++G Sbjct: 331 FDDPTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKD---------KTYS-NNLDYLDENAG 380 Query: 247 FYKNVVK 253 N +K Sbjct: 381 KLSNRMK 387 >1LXM-A nrPDB Length = 814 Score = 31.2 bits (69), Expect = 0.96, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 23/93 (24%) Query: 189 VPLVIQMTDDEKYL-----WKDLTLDQAYSYAVE--------------NAKDIIACGFDI 229 VPL + + ++ + W D+T+ Y Y NAK+I A D Sbjct: 70 VPLSVTASTEDNFTKLLDKWNDVTIGN-YVYDTNDSNMQKLNQKLDETNAKNIEAIKLDS 128 Query: 230 NKTFIFSDLDYMGMSSGF---YKNVVKIQKHVT 259 N+TF++ DLD + S+ Y+ + + K +T Sbjct: 129 NRTFLWKDLDNLNNSAQLTATYRRLEDLAKQIT 161 >2YY5-A nrPDB Length = 348 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 22/119 (18%) Query: 219 AKDIIACGFDINKTFIF--SDL---DYMGMSSGFYKNVVKIQKHVTFN-----QVKGIFG 268 + ++A G D K +F SDL MG N+ ++Q+ F Q + G Sbjct: 65 VRTLLAVGLDPQKACLFLQSDLLEHSMMGYLMMVQSNLGELQRMTQFKAKKAEQTRNPNG 124 Query: 269 FTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRI 327 T + G +++PA+ A I + DI +P DQ + +TRD+A RI Sbjct: 125 -TLNIPTGLLTYPALMAGD--------ILLYQPDI---VPVGNDQKQHLELTRDLAQRI 171 >3TS1-A nrPDB Length = 419 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 11/42 (26%), Positives = 24/42 (57%) Query: 152 NKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 N++ LY G P+++++H+GHL + + Q + P+ + Sbjct: 27 NEERVTLYCGFDPTADSLHIGHLATILTMRRFQQAGHRPIAL 68 >1TYB-E nrPDB Length = 319 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 11/42 (26%), Positives = 24/42 (57%) Query: 152 NKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 N++ LY G P+++++H+GHL + + Q + P+ + Sbjct: 27 NEERVTLYCGFDPTADSLHIGHLAGILTMRRFQQAGHRPIAL 68 >2RKJ-A nrPDB Length = 392 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 159 YTGRGPSSEAMHVGHLIPFIFTKWL 183 Y G P++ ++HVGHL+P + W+ Sbjct: 68 YVGIDPTAPSLHVGHLLPLMPLFWM 92 >6DFU-A nrPDB Length = 337 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 45/176 (25%) Query: 223 IACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDC-------I 275 +ACG D NK+ IF + + + + F ++ + F D + Sbjct: 71 LACGIDPNKSTIFVQSHVPEHTQLSW----VLNCYTYFGEMSRMTQFKDKSARYAENINV 126 Query: 276 GKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALL 335 G +P + AA +++ ++ +P DQ + +TRD+A R AL Sbjct: 127 GLFDYPVLMAADIL------LYQAKS-----VPVGDDQKQHLEITRDIANRFN----ALY 171 Query: 336 HSTF-------------FPALQGAQTKMSASDPNSSIFLT------DTAKQIKTKV 372 + F +LQ + KMS SD N + +T AK+IK V Sbjct: 172 GNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAV 227 >6MTK-A nrPDB Length = 329 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 25/157 (15%) Query: 306 LIPCAIDQDPYFRMTRDVAPRIG--------YPKPALLHST-FFPALQGAQTKMSASDPN 356 ++P DQ + +TRDVA + P + ST + P G KMS S N Sbjct: 149 VVPVGKDQLQHLEITRDVAEKFNRQMGEVFVLPGAEIQESTKYVPGTDGH--KMSKSRGN 206 Query: 357 -SSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQ 415 +IFL + K++K ++ + ++EE + + + D +F+ + + ++ E Sbjct: 207 IINIFLPE--KELKKQI--MSIESDSKSLEEPK----DPETDKTFI-IYALIATPEQTEA 257 Query: 416 IRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEV 452 +R+ Y +G G K L+ LI E A+ +E+ Sbjct: 258 LRQKYLAGNFGYGHAKTELLN----LILERFAKEREL 290 >2EBS-A nrPDB Length = 789 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 22/41 (53%) Query: 322 DVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLT 362 D+ PR+G PA ++ FPA + A++PN + +T Sbjct: 274 DITPRVGNSSPAPYNNQTFPAGGFCGLSVDATNPNRLVVIT 314 >6N0W-A nrPDB Length = 480 Score = 28.1 bits (61), Expect = 7.5, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 17/124 (13%) Query: 152 NKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI-----QMTDD--EKYLWK 204 NK+ Y G P+++++H+G LIP Q + P+ + M D K + Sbjct: 34 NKEMTTAYIGFDPTADSLHIGSLIPIKILAHFQRHGHKPIALVGGATGMIGDPSGKSAER 93 Query: 205 DLTLDQAYSYAVENAKDIIACGFDI-----NKTFIFSDLDYMGMSS--GFYKNVVKIQKH 257 +L ++ Y V+ K+ ++ D N+ + ++ D+M + F KN I KH Sbjct: 94 NLLDEETLLYYVDCLKNQLSRFLDFEGDGPNRAELVNNYDWMKNVTFLDFAKN---IGKH 150 Query: 258 VTFN 261 +T N Sbjct: 151 ITVN 154 >5V0I-A nrPDB Length = 337 Score = 28.1 bits (61), Expect = 9.3, Method: Compositional matrix adjust. Identities = 38/168 (22%), Positives = 66/168 (39%), Gaps = 29/168 (17%) Query: 223 IACGFDINKTFIF-----SDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGK 277 +ACG D K+ IF + +G + Y ++ + F + ++ G Sbjct: 71 LACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSA--RYAENINAGL 128 Query: 278 ISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--------Y 329 +P + AA I +T+ L+P DQ + ++RD+A R Sbjct: 129 FDYPVLMAA--------DILLYQTN---LVPVGEDQKQHLELSRDIAQRFNALYGDIFKV 177 Query: 330 PKPALLHS-TFFPALQGAQTKMSASDPNSS--IFLTDTAKQIKTKVNK 374 P+P + S +L KMS SD N + I L + K + K+ + Sbjct: 178 PEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKR 225 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1R6T-A nrPDB 749 0.0 5UJI-A nrPDB 572 e-163 3KT6-A nrPDB 513 e-146 3HV0-A nrPDB 505 e-143 3I05-A nrPDB 499 e-141 4J75-A nrPDB 491 e-139 3TZE-A nrPDB 468 e-132 3FOC-A nrPDB 431 e-121 3JXE-A nrPDB 431 e-121 3HZR-A nrPDB 396 e-111 3A04-A nrPDB 327 9e-90 2CYB-A nrPDB 223 1e-58 1YID-B nrPDB 221 5e-58 2CYA-A nrPDB 203 1e-52 6NCR-A nrPDB 201 7e-52 2G36-A nrPDB 196 2e-50 3VGJ-A nrPDB 189 3e-48 2J5B-A nrPDB 187 9e-48 3P0I-A nrPDB 184 6e-47 5DK4-A nrPDB 176 2e-44 2CYC-A nrPDB 164 1e-40 2DLC-X nrPDB 131 6e-31 6OTJ-A nrPDB 81 9e-16 1JIJ-A nrPDB 79 3e-15 Sequences not found previously or not previously below threshold: 5NSF-B nrPDB 151 8e-37 2EL7-A nrPDB 151 1e-36 3PRH-A nrPDB 146 2e-35 3U1V-A nrPDB 146 3e-35 5V0I-A nrPDB 128 6e-30 3N9I-A nrPDB 124 7e-29 6DFU-A nrPDB 124 1e-28 3SZ3-A nrPDB 121 8e-28 5EKD-A nrPDB 111 8e-25 6MTK-A nrPDB 107 1e-23 2YY5-A nrPDB 103 2e-22 3TZL-A nrPDB 101 5e-22 4Q93-A nrPDB 94 2e-19 5TEW-A nrPDB 86 4e-17 3TS1-A nrPDB 74 2e-13 1TYB-E nrPDB 73 2e-13 6BQZ-A nrPDB 72 3e-13 2JAN-A nrPDB 72 4e-13 4OUD-B nrPDB 71 8e-13 1H3F-A nrPDB 71 1e-12 6HB6-A nrPDB 69 4e-12 1X8X-A nrPDB 69 4e-12 6BYQ-A nrPDB 61 1e-09 6N0W-A nrPDB 61 2e-09 5IHX-A nrPDB 56 4e-08 5IJX-A nrPDB 49 4e-06 2RKJ-A nrPDB 46 4e-05 2PID-A nrPDB 39 0.007 2DJV-A nrPDB 38 0.012 2VA8-A nrPDB 36 0.029 4E4R-A nrPDB 33 0.34 4Z5Q-A nrPDB 32 0.80 6G9C-A nrPDB 31 1.00 2Y7H-B nrPDB 30 2.7 3LAD-A nrPDB 30 2.8 2REO-A nrPDB 29 3.4 5U8W-A nrPDB 29 3.8 4ZTY-A nrPDB 29 4.5 5YZG-y nrPDB 28 7.8 4ITN-A nrPDB 28 8.2 >1R6T-A nrPDB Length = 477 Score = 749 bits (1934), Expect = 0.0, Method: Composition-based stats. Identities = 464/467 (99%), Positives = 465/467 (99%) Query: 1 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA Sbjct: 1 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 Query: 61 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 120 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI Sbjct: 61 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 120 Query: 121 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 180 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT Sbjct: 121 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 180 Query: 181 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 240 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAY AVENAKDIIACGFDINKTFIFSDLDY Sbjct: 181 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYGDAVENAKDIIACGFDINKTFIFSDLDY 240 Query: 241 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 300 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR Sbjct: 241 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 300 Query: 301 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 360 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF Sbjct: 301 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 360 Query: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 420 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY Sbjct: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 420 Query: 421 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLS 467 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL+ Sbjct: 421 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLA 467 >5UJI-A nrPDB Length = 388 Score = 572 bits (1473), Expect = e-163, Method: Composition-based stats. Identities = 374/375 (99%), Positives = 374/375 (99%) Query: 97 GIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPF 156 GIDYDKLIVRFGSSKIDKELINRIERATGQRPH FLRRGIFFSHRDMNQVLDAYENKKPF Sbjct: 1 GIDYDKLIVRFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQVLDAYENKKPF 60 Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV Sbjct: 61 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 120 Query: 217 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG 276 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG Sbjct: 121 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG 180 Query: 277 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH 336 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH Sbjct: 181 KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLH 240 Query: 337 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV 396 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV Sbjct: 241 STFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDV 300 Query: 397 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI 456 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI Sbjct: 301 DVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEI 360 Query: 457 VKEFMTPRKLSFDFQ 471 VKEFMTPRKLSFDFQ Sbjct: 361 VKEFMTPRKLSFDFQ 375 >3KT6-A nrPDB Length = 438 Score = 513 bits (1321), Expect = e-146, Method: Composition-based stats. Identities = 216/396 (54%), Positives = 289/396 (72%), Gaps = 8/396 (2%) Query: 77 ATEAEEDFVDPWTVQTS-----SAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHF 131 +T+ +E V PW V+ A+ IDYDKLI +FG+ +++E + R ++ TG+ PHHF Sbjct: 19 STDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKRFKQVTGREPHHF 78 Query: 132 LRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPL 191 LR+G+FFS RD ++LD YE KPF+LYTGRGPSS++MH+GH+IPF+FTKWLQ+VF+VPL Sbjct: 79 LRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQEVFDVPL 138 Query: 192 VIQMTDDEKYLW-KDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKN 250 VI++TDDEK+L+ LT++ ++A ENAKDIIA GFD TFIFSDL YMG FY+ Sbjct: 139 VIELTDDEKFLFKHKLTINDVKNFARENAKDIIAVGFDPKNTFIFSDLQYMG--GAFYET 196 Query: 251 VVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCA 310 VV++ + +T + K +FGF DSDCIGK F +IQ A +F +SFP + CLIPCA Sbjct: 197 VVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCA 256 Query: 311 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370 IDQDPYFR+ RDVA ++ Y KPALLHS FFPALQG+ TKMSASD ++IF+TDT KQI+ Sbjct: 257 IDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQK 316 Query: 371 KVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGEL 430 K+NK+AFSGG+ + + HR+ GGN DVDV++ YL+FF +DD L++ Y SG +L+GE+ Sbjct: 317 KINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKYKSGELLSGEM 376 Query: 431 KKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 KK IE LQ + Q RR +V +E + +FM P KL Sbjct: 377 KKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKL 412 >3HV0-A nrPDB Length = 393 Score = 505 bits (1301), Expect = e-143, Method: Composition-based stats. Identities = 217/380 (57%), Positives = 289/380 (76%), Gaps = 4/380 (1%) Query: 87 PWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQV 146 PW V+ +A GIDY+KLI +FG I K++I R+ER TGQ+ HHF RR IF SHRD ++ Sbjct: 6 PWEVKADNAYGIDYNKLIDKFGCKLITKDMIERMERLTGQKAHHFFRRNIFLSHRDFEKI 65 Query: 147 LDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK-D 205 LD YE + FYLYTGRGPSSE++HVGHL+PF+FTK+LQD F VPLVIQ+TDDEK+++K + Sbjct: 66 LDVYEKGELFYLYTGRGPSSESLHVGHLVPFLFTKYLQDTFKVPLVIQLTDDEKFIFKSN 125 Query: 206 LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKG 265 LTL++ ++YA EN KDIIACGFD TFIF++L+Y+ Y ++++I+K ++ +Q+K Sbjct: 126 LTLEETHNYAYENMKDIIACGFDPELTFIFTNLEYIA---ELYPDILRIEKKISCSQIKS 182 Query: 266 IFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAP 325 IFGF DS +GK +FPA+QAAP+FS+SFP IF RTDI CL+P AIDQDPYFRM RDVAP Sbjct: 183 IFGFKDSCNVGKFAFPAVQAAPAFSSSFPHIFGGRTDIHCLVPHAIDQDPYFRMVRDVAP 242 Query: 326 RIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIE 385 R+GY KP+ +HS F P+LQG+QTKMSAS NSSIF+ D + I+ K+ K+AFSGG+ T E Sbjct: 243 RLGYLKPSSIHSIFLPSLQGSQTKMSASVQNSSIFVNDNEESIRNKIMKYAFSGGQATEE 302 Query: 386 EHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEH 445 E R+ G N DVDVS+ YL F +EDD+KLE+I K Y+SG ML+GE+K L++ L L H Sbjct: 303 EQRRLGANLDVDVSWQYLRFLMEDDEKLEEIGKKYSSGEMLSGEIKSILVQELVKLTKNH 362 Query: 446 QARRKEVTDEIVKEFMTPRK 465 Q R+ + D+++ +F + Sbjct: 363 QKNREAINDDVIAKFTNKSR 382 >3I05-A nrPDB Length = 395 Score = 499 bits (1285), Expect = e-141, Method: Composition-based stats. Identities = 217/384 (56%), Positives = 279/384 (72%), Gaps = 9/384 (2%) Query: 82 EDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHR 141 E V PW+V+ ++YDKLI FGS ID+ L+ RIER G++PHHFLRRGIFFSHR Sbjct: 9 EAVVTPWSVEGD----VNYDKLIKDFGSHAIDEALLERIERVLGKKPHHFLRRGIFFSHR 64 Query: 142 DMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKY 201 D+N +LD YE+ +PFYLYTGRGPSSE+MH+GHLIPF+FTKWLQD F VPLVIQMTDDEK+ Sbjct: 65 DLNLLLDVYESGQPFYLYTGRGPSSESMHMGHLIPFMFTKWLQDSFRVPLVIQMTDDEKF 124 Query: 202 LWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFN 261 ++++ ++Q + EN KDIIA GFD TFIF D DYMG Y+ V KI++ T + Sbjct: 125 YFRNIPMEQVEAMTTENIKDIIAMGFDPELTFIFRDFDYMGC---MYRTVAKIERAFTAS 181 Query: 262 QVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIF-RDRTDIQCLIPCAIDQDPYFRMT 320 QV+G FGF D G+ FPAIQAAPSFS +FP IF ++ CLIP AIDQDPYFR+T Sbjct: 182 QVRGCFGFAMEDNCGRWMFPAIQAAPSFSAAFPHIFPPSMGNVFCLIPQAIDQDPYFRLT 241 Query: 321 RDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGG 380 RD+APR+GY KPA++HS FFP L G + KMS+S +++ LTDT K +K K+NKHAFSGG Sbjct: 242 RDIAPRLGYLKPAVIHSKFFPGLSGPKGKMSSSS-GTAVLLTDTEKMVKDKINKHAFSGG 300 Query: 381 RDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQP 440 T +EH G N +VDV +L+FFLEDD++L +++K+Y G ++TGE+KK LI + Sbjct: 301 GATKQEHFLLGANVEVDVPIQWLSFFLEDDEELARVKKEYMLGRIMTGEVKKLLINTITA 360 Query: 441 LIAEHQARRKEVTDEIVKEFMTPR 464 + HQ +RK VTDE V+ F + R Sbjct: 361 ITKTHQEKRKLVTDEDVQLFTSTR 384 >4J75-A nrPDB Length = 409 Score = 491 bits (1263), Expect = e-139, Method: Composition-based stats. Identities = 200/411 (48%), Positives = 268/411 (65%), Gaps = 24/411 (5%) Query: 74 GPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLR 133 GP + + V PW V ++ +GI+Y+KLI FG SKI + I RIE+ T + HHF+R Sbjct: 1 GPGSMSKD---VTPWDVNINNEEGINYNKLIKEFGCSKITENHIKRIEKLTNSKAHHFIR 57 Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RGIFFSHRD++ +L+ YE K FY+YTGRGPSS +MH+GHLIPF F K+LQ+ FNVPLVI Sbjct: 58 RGIFFSHRDLDFLLNYYEQHKCFYIYTGRGPSSLSMHLGHLIPFYFCKYLQEAFNVPLVI 117 Query: 194 QMTDDEKYLW-KDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVV 252 Q++DDEKYL+ ++ +L+ + EN KDII+ G + TFIF + +Y G Y V+ Sbjct: 118 QLSDDEKYLFNQNYSLEYINTLTNENVKDIISVGLNPELTFIFKNTEYAGY---LYPTVL 174 Query: 253 KIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAID 312 I K T NQ +FGF SD IGKIS+P+ Q AP FS FP +I CL+P ID Sbjct: 175 SIHKKTTLNQSMNVFGFNHSDNIGKISYPSFQIAPCFSQCFPNFL--GKNIPCLVPQGID 232 Query: 313 QDPYFRMTRDVAPRIGYPKPALLHSTFFPALQG---------------AQTKMSASDPNS 357 QDPYFR++RD+A ++ KP ++HS F P LQG ++ + NS Sbjct: 233 QDPYFRLSRDIAVKMALHKPVVVHSVFMPGLQGVNSKMSSTKKKKDDNGKSNSTFDHNNS 292 Query: 358 SIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIR 417 IFLTDT +QIK K+NK+AFSGG TI+EHR+ GGN D D+S+ YL + LEDD+KL +I Sbjct: 293 VIFLTDTPEQIKNKINKYAFSGGGTTIQEHREKGGNLDKDISYQYLRYLLEDDNKLNEIG 352 Query: 418 KDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSF 468 + Y G ML+GE+KK LI+VL L+ +HQ ++K +TDE + F P K S Sbjct: 353 EKYKKGEMLSGEIKKILIDVLTELVLKHQEKKKSLTDEEISYFFDPNKPSL 403 >3TZE-A nrPDB Length = 406 Score = 468 bits (1203), Expect = e-132, Method: Composition-based stats. Identities = 181/398 (45%), Positives = 258/398 (64%), Gaps = 12/398 (3%) Query: 73 HGPDATEAEEDFVDPWTVQTSSAK----GIDYDKLIVRFGSSKIDKELINRIERATGQRP 128 GP + E + PW V+ S IDYDK+I +FG K ++ L +R+E+ +G+ Sbjct: 17 QGPGS--MAEQRITPWDVEVVSTDEVPVAIDYDKIINQFGCEKFNQALADRLEKLSGKPA 74 Query: 129 HHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFN 188 H+F RRGI F+HRD N +LD N +PFYLYTGRGPSS+ MH+GH IPF+ K++QD F Sbjct: 75 HYFFRRGIVFAHRDFNLLLDEIANNRPFYLYTGRGPSSKTMHIGHTIPFLLCKYMQDAFK 134 Query: 189 VPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFY 248 + LVIQ+TDDEK+LWK + L+ A +Y EN KDI+ GFD T+IFS+++ S F Sbjct: 135 IRLVIQITDDEKFLWKSMRLEDAMAYGRENIKDIVTLGFDPKLTYIFSNVE---ASHHFE 191 Query: 249 KNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIP 308 +N++KI K + N+ +FGF S IG++ FPA + AP FS+SF I CL+P Sbjct: 192 ENILKISKTINLNEAIKVFGFDMSSNIGQVGFPAKEIAPCFSSSFRFI---GKGAMCLVP 248 Query: 309 CAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQI 368 A+DQDP+FR+ RD A +G KP+ ++ + P L+G KMSASDPNSSI+L D I Sbjct: 249 AAVDQDPFFRLARDKAKALGEKKPSSIYVSLLPDLKGVNRKMSASDPNSSIYLDDAQDTI 308 Query: 369 KTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTG 428 + K+ +A+SGGR T+EEHR+ GG+ DVDV F YL +FL+DD +LE+ R Y G + + Sbjct: 309 RKKIIAYAYSGGRKTLEEHREKGGDIDVDVPFEYLKYFLDDDQELEKYRSGYIKGEITSK 368 Query: 429 ELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 E+K+ + V+Q ++ +Q RK VTD+ ++ F+ K Sbjct: 369 EMKEKCVVVIQEFVSRYQESRKRVTDDDLRAFIDINKF 406 >3FOC-A nrPDB Length = 451 Score = 431 bits (1109), Expect = e-121, Method: Composition-based stats. Identities = 180/413 (43%), Positives = 248/413 (60%), Gaps = 50/413 (12%) Query: 103 LIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGR 162 +I RFG++ I +L+ R E TG + H LRRG+F++HRD + L YE P Y+YTGR Sbjct: 39 IITRFGAAPITDDLLKRFETVTGTKAHPMLRRGLFYAHRDFEEFLSYYEKGHPIYIYTGR 98 Query: 163 GPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYL-WKDLTLDQAYSYAVENAKD 221 GPSS A+H+GHL+PFIFTK+LQD F +VIQ+TDDEK+L + L+ + SY EN KD Sbjct: 99 GPSSGALHLGHLLPFIFTKYLQDAFKCYVVIQITDDEKFLRNRSLSYAEVDSYTRENIKD 158 Query: 222 IIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFP 281 IIACGFD +KTFIF + Y+ + + Y+ + + + +Q++ FGF++ +G +FP Sbjct: 159 IIACGFDPDKTFIFINSQYLSLKNR-YRFSCLVDRMLPISQLRASFGFSNDANVGYAAFP 217 Query: 282 AIQAAPSFSNSFPQIFRDRTDIQ------------------------------------- 304 Q P +S F + R + Sbjct: 218 PKQMLPVYSTYFDGLPFTRVPLPVGTGNEDAADAVSTKKASKKTPKKDAVLSPVHVVEEL 277 Query: 305 -----------CLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSAS 353 CLI I+QDPYFR+ RD+APR+G+PK A L F P LQG+ TKMSAS Sbjct: 278 FPDSKRYQKAMCLIASGIEQDPYFRLARDLAPRMGHPKNAYLLGKFLPGLQGSGTKMSAS 337 Query: 354 DPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKL 413 DPNS+I+LTDT QIK K+N++AFSGGRDT EEHR FG + VDVS YL F++DD +L Sbjct: 338 DPNSAIYLTDTPAQIKNKINRYAFSGGRDTEEEHRAFGADLSVDVSVRYLEVFMKDDAEL 397 Query: 414 EQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 E+++ DY +G +LTGE+K LI +LQ LI EH RR +V +++ F ++L Sbjct: 398 EKLKADYKTGKLLTGEVKATLIGILQGLIKEHAERRDKVDTTMIESFTVKKEL 450 >3JXE-A nrPDB Length = 392 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 172/390 (44%), Positives = 237/390 (60%), Gaps = 22/390 (5%) Query: 80 AEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFS 139 EE V PW V+ +DYDKLI FG+S + ++L+ + T F RR FFS Sbjct: 2 VEEFKVTPWEVEGV----VDYDKLIKHFGTSPLTEDLLEKTAELTKSELPIFFRRKFFFS 57 Query: 140 HRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDE 199 HRD + +L YE + F+LYTGRGPS MH+GH+IPF TKWLQ+ F V L IQ+TDDE Sbjct: 58 HRDYDLILKDYEEGRGFFLYTGRGPSG-PMHIGHIIPFFATKWLQEKFGVNLYIQITDDE 116 Query: 200 KYLWK-DLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHV 258 K+L+K +LT D +A +N DIIA GFD +KTFIF + ++ + Y+ + I K + Sbjct: 117 KFLFKENLTFDDTKRWAYDNILDIIAVGFDPDKTFIFQNSEF----TKIYEMAIPIAKKI 172 Query: 259 TFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFR 318 F+ K +FGFT+ IG I FPAIQ AP+F +CLIP AIDQDPY+R Sbjct: 173 NFSMAKAVFGFTEQSKIGMIFFPAIQIAPTFFE----------RKRCLIPAAIDQDPYWR 222 Query: 319 MTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFS 378 + RD A +GY K A LHS F P+L KMSAS P ++I+LTD+ + ++ KV K + Sbjct: 223 LQRDFAESLGYYKTAALHSKFVPSLTSLSGKMSASKPETAIYLTDSPEDVEKKVWKFTLT 282 Query: 379 GGRDTIEEHRQFGGNCDVDVSFMYLT-FFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV 437 GGR T++E R+ GG + V F +L FF EDD KL++ +G + GE K+ LI Sbjct: 283 GGRPTLKEQREKGGEPEKCVVFKWLEIFFEEDDKKLKERYYACKNGELTCGECKRYLISK 342 Query: 438 LQPLIAEHQARRKEVTDEIVKEFMTPRKLS 467 +Q + EHQ RRK+ +++V++F KL+ Sbjct: 343 IQEFLKEHQRRRKKA-EKLVEKFKYTGKLA 371 >3HZR-A nrPDB Length = 386 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 128/377 (33%), Positives = 221/377 (58%), Gaps = 7/377 (1%) Query: 90 VQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDA 149 +Q+ + + DY++LI G + I + I RIE+ +G+ PHH+L RG+F + + +++ LD Sbjct: 17 LQSFTTRTTDYNQLINSVGINAITPQQIQRIEKLSGKAPHHYLSRGVFLAEKSLDKFLDD 76 Query: 150 YENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLD 209 E KKP +++ + P E + + I F ++LQD FN+ ++IQ+ DD K L ++ T++ Sbjct: 77 VEAKKPTFIFIQKYPQKE-VALEEYITLEFARYLQDAFNIQVIIQILDDIKVLNREATIN 135 Query: 210 QAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGF 269 +A + + K I+A GF+ +KTFI++D Y G Y+ + ++K +N V+ F F Sbjct: 136 EASKMSNDLMKYILAFGFNEDKTFIYTDYQYFG---KMYRTISLVEKATAYNVVQPFFNF 192 Query: 270 TDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGY 329 SD IGK++ P+I A FS S+ F + +CL+ +I + + +A + + Sbjct: 193 EYSDNIGKLASPSIMTASMFSQSYSHFF--SSPARCLVLDSIKNVQFHSIIDQIATTLNF 250 Query: 330 PKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQ 389 +P +L P L G TK ++SI L+D AKQ++ K+NK AFSGGR+T EEH++ Sbjct: 251 IQPTVLFHKMVPLLSGV-TKFDIPSDHNSILLSDNAKQVERKINKLAFSGGRNTTEEHKK 309 Query: 390 FGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARR 449 GG CD+DVSF L F D+ +++ + + Y+ G +L+GELKK + ++ I + A++ Sbjct: 310 LGGQCDIDVSFQLLNIFSSDNAQVKDVEEKYSKGELLSGELKKIVSASMKDFIVAYDAKK 369 Query: 450 KEVTDEIVKEFMTPRKL 466 K +T +K +++ K Sbjct: 370 KPITTAYLKAYISKTKF 386 >3A04-A nrPDB Length = 372 Score = 327 bits (837), Expect = 9e-90, Method: Composition-based stats. Identities = 109/379 (28%), Positives = 182/379 (48%), Gaps = 28/379 (7%) Query: 83 DFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRD 142 + +DPW + + DYD+L+ FG + L + R G P +RRGI F HRD Sbjct: 4 ERLDPW----GAVEIKDYDRLLRTFGIRPFSEVL--PLLRKAGMEPSFLMRRGIIFGHRD 57 Query: 143 MNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYL 202 +++L+A + + TG PS + H GH + +LQ + + + D E + Sbjct: 58 FDKILEAKARGERVAVLTGFMPSGK-FHFGHKLTVDQLIYLQKN-GFKVFVAIADAEAFA 115 Query: 203 WKDLTLDQAYSYAVEN-AKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFN 261 + + ++A AVE ++IA G D T + + + +++ + VT Sbjct: 116 VRRIGREEAVRIAVEEYIANMIALGLDPKDTEFYFQTN---RGTPYFRLIQLFSGKVTAA 172 Query: 262 QVKGIFG-FTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMT 320 +++ I+G T + + ++ QAA + R ++P DQDP+ R+T Sbjct: 173 EMEAIYGELTPAKMMASLT----QAADILHVQLDEYGGYR---HVVVPVGADQDPHLRLT 225 Query: 321 RDVAPRIG----YPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHA 376 RD+A R+ +PA + P L G KMS+S P+S+IFLTD + + K+ + A Sbjct: 226 RDLADRMAGVVELERPASTYHKLQPGLDG--RKMSSSRPDSTIFLTDPPEVARNKLFR-A 282 Query: 377 FSGGRDTIEEHRQFGGNCDVD-VSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALI 435 +GGR T EE R+ GG +V V M L + DD +++ I G +L GE K+ Sbjct: 283 LTGGRATAEEQRRLGGVPEVCSVYHMDLYHLMPDDGEVKHIYTSCRLGKILCGECKQIAW 342 Query: 436 EVLQPLIAEHQARRKEVTD 454 E L+ +AEHQ+R ++ Sbjct: 343 EKLERFLAEHQSRLEKAKT 361 >2CYB-A nrPDB Length = 323 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 72/336 (21%), Positives = 137/336 (40%), Gaps = 58/336 (17%) Query: 137 FFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMT 196 + ++ Q+++ E + Y G PS E +H+GH++ LQ+ +++ + Sbjct: 17 VVTEEELRQLIETKEKPRA---YVGYEPSGE-IHLGHMMTVQKLMDLQEA-GFEIIVLLA 71 Query: 197 DDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQK 256 D YL + T ++ A N K IA G D ++ +Y +S + +V+K+ + Sbjct: 72 DIHAYLNEKGTFEEIAEVADYNKKVFIALGLDESRAKFVLGSEYQ-LSRDYVLDVLKMAR 130 Query: 257 HVTFNQVK----GIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAID 312 T N+ + + + + ++ +P +QA L ID Sbjct: 131 ITTLNRARRSMDEVSRRKEDPMVSQMIYPLMQALDIAHLGVD-----------LAVGGID 179 Query: 313 QDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKV 372 Q + R+ PR+GY P LH+ L G KMS+S N I + D ++++ K+ Sbjct: 180 QRKIHMLARENLPRLGYSSPVCLHTPILVGLDG--QKMSSSKGN-YISVRDPPEEVERKI 236 Query: 373 NKHAFSG--------------------GRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDK 412 K G+ +E +FGG+ + Y +F Sbjct: 237 RKAYCPAGVVEENPILDIAKYHILPRFGKIVVERDAKFGGDVE------YASF------- 283 Query: 413 LEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQAR 448 E++ +D+ SG + +LK A+ + L L+ + + R Sbjct: 284 -EELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARKR 318 >1YID-B nrPDB Length = 351 Score = 221 bits (563), Expect = 5e-58, Method: Composition-based stats. Identities = 77/308 (25%), Positives = 126/308 (40%), Gaps = 34/308 (11%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTK-WLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 + TG P+ A+H+GHL + + LQD L + + D + +Q + Sbjct: 25 VLTGDRPTG-ALHLGHLAGSLQNRVRLQD--EAELFVLLADVQALTDHFDRPEQVRENVL 81 Query: 217 ENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIF---GFTD 271 A D +A G D KT + S + + + ++ N+V + VK G+ + Sbjct: 82 AVALDYLAAGLDPQKTTCVVQSAVPELAELTVYFLNLVTVSHLRQNPTVKAEIAQKGYGE 141 Query: 272 SDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDV-------- 323 G +P QAA + L+P DQ P TR++ Sbjct: 142 RVPAGFFVYPVSQAADIAAFG-----------ATLVPVGDDQLPMLEQTREIVRRFNALY 190 Query: 324 APRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDT 383 AP + P+ L P L G Q KMS S N +I L D+A ++ KV G Sbjct: 191 APVLAEPQAQLSRVPRLPGLDG-QAKMSKSLGN-AIALGDSADEVARKVMGMYTDPGHLR 248 Query: 384 IEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIA 443 + + GN F +L F D +++ ++ Y +G + ++KK LI+VL ++A Sbjct: 249 ASDPGRVEGNP----VFTFLDAFDPDPARVQALKDQYRAGGLGDVKVKKHLIDVLNGVLA 304 Query: 444 EHQARRKE 451 + RR E Sbjct: 305 PIRTRRAE 312 >2CYA-A nrPDB Length = 364 Score = 203 bits (516), Expect = 1e-52, Method: Composition-based stats. Identities = 72/349 (20%), Positives = 132/349 (37%), Gaps = 65/349 (18%) Query: 137 FFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDV---FNVPLVI 193 + ++ +L + Y G PS A H+G L+ K L + F+V Sbjct: 20 IVTEEELKGLL---ASGARIKGYIGYEPSGVA-HIGWLVWMYKVKDLVEAGVDFSVLEAT 75 Query: 194 QMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVK 253 L D+ L +A + V + A G + + F D + + ++ V++ Sbjct: 76 WHAYINDKLGGDMDLIRAAARIVRRVME--AAGVPVERVR-FVDAEELASDKDYWGLVIR 132 Query: 254 IQKHVTFNQVK---GIFGFTDSDC---IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLI 307 + K + +V+ I G + K+ +P +Q + F + Sbjct: 133 VAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYMDLD-----------IA 181 Query: 308 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQG---------------AQTKMSA 352 +DQ + RDVA ++G KP +H+ +LQG A+ KMS Sbjct: 182 LGGMDQRKAHMLARDVAEKLGRKKPVAIHTPIISSLQGPGRMEASQGEIDDVLAEVKMSK 241 Query: 353 SDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYL----TFFLE 408 S P +++F+ D+ I+ K+ K +Q GN ++++ L F L Sbjct: 242 SKPETAVFVVDSDDDIRRKIRKAYCPA--------KQVQGNPVLEIARYILFARDGFTLR 293 Query: 409 DD-----------DKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQ 446 D E++ +DYT G + +LK A+ E L ++ + Sbjct: 294 VDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIR 342 >6NCR-A nrPDB Length = 354 Score = 201 bits (510), Expect = 7e-52, Method: Composition-based stats. Identities = 70/326 (21%), Positives = 129/326 (39%), Gaps = 53/326 (16%) Query: 154 KPFYLYTGRGPSSEAMHVGHLIPFIFTK-WLQDVFNVPLVIQMTDDEKYLW--KDLTLDQ 210 K + TG P+ + +H+GH I I + LQ+ + D + + Q Sbjct: 10 KKKRVLTGDRPTGK-LHLGHWIGSIMNRLQLQNDSRYDCFFIIADLHTLTTKTRKEEILQ 68 Query: 211 AYSYAVENAKDIIACGFDINKT---------------FIFSDLDYMGMSSGFYKNVVKIQ 255 ++ + D ++ G D K+ IFS L + G ++ ++ Sbjct: 69 IDNHIYDVLADWLSVGIDPEKSAIYLQSAIPEIYELNLIFSMLTPLNHIMG-IPSIKEMA 127 Query: 256 KHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDP 315 ++ + N+ +S G I +P +Q+A L+P D + Sbjct: 128 RNASLNE--------ESLSHGLIGYPVLQSADILLAKAH-----------LVPVGKDNEA 168 Query: 316 YFRMTRDVAPRIG------YPKPALLHSTFFPALQG--AQTKMSASDPNSSIFLTDTAKQ 367 + +TRD+A +P+P +L AL G Q KMS S N++I+L+D AK Sbjct: 169 HVELTRDIAKTFNRLYGEVFPEPDILQGE-LTALVGTNGQGKMSKS-ANNAIYLSDDAKT 226 Query: 368 IKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLT 427 ++ K+ K R H G + + F+Y F +++E+ + Y G + Sbjct: 227 VQEKIRKLYTDPNRI----HATTPGRVEGNPLFIYHDLFNPHKEEVEEFKTRYRQGCIRD 282 Query: 428 GELKKALIEVLQPLIAEHQARRKEVT 453 E+K L E + + + +R E+ Sbjct: 283 VEVKARLAEEINLFLNPFREKRSELV 308 >2G36-A nrPDB Length = 340 Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats. Identities = 56/311 (18%), Positives = 128/311 (41%), Gaps = 32/311 (10%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKW--LQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 + +G P+ + +H+GHL+ + W LQ+ N + D + + Y Sbjct: 15 ILSGMRPTGK-LHIGHLVGAL-ENWVKLQEEGN-ECFYFVADWHALTTHYDDVSKLKEYT 71 Query: 216 VENAKDIIACGFDINKTFIF-----SDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFT 270 + + +ACG D K+ IF + + + +V ++++ T+ ++K + Sbjct: 72 RDLVRGFLACGIDPEKSVIFVQSGVKEHAELALLFSMIVSVSRLERVPTYKEIKSELNYK 131 Query: 271 DSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGY- 329 D G + +P +QAA I++ +P DQ + +TR++A R Y Sbjct: 132 DLSTAGFLIYPVLQAADIL------IYKAEG-----VPVGEDQVYHIELTREIARRFNYL 180 Query: 330 -----PKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTI 384 P+P + S P L G + + + I L + K+++ + + R Sbjct: 181 YDEVFPEPEAILSR-VPKLPGTDGRKMSKSYGNIINLEISEKELEQTILRMMTDPARVRR 239 Query: 385 EEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAE 444 + GN + + Y F +++ + + + T+ ++ + KK L++ ++ +A Sbjct: 240 SDP----GNPENCPVWKYHQAFDISEEESKWVWEGCTTASIGCVDCKKLLLKNMKRKLAP 295 Query: 445 HQARRKEVTDE 455 +++ ++ Sbjct: 296 IWENFRKIDED 306 >3VGJ-A nrPDB Length = 373 Score = 189 bits (479), Expect = 3e-48, Method: Composition-based stats. Identities = 74/322 (22%), Positives = 124/322 (38%), Gaps = 53/322 (16%) Query: 153 KKPFYLYTGRGPSSEAMHV--GHLIPFIFTK----------WLQDVFNVPLVIQMTDDEK 200 K+ Y G PS MH+ G L I K W+ D F L +M+ D K Sbjct: 54 KRKLICYDGFEPSGR-MHIAQGLLKSIIVNKLTSNGCTFIFWIADWF-AHLNNKMSGDLK 111 Query: 201 YLWKDLTLDQAYSYAVENAKDIIACGFDINKT-FIFSDLDYMGMSSGFYKNVVKIQKHVT 259 + + SY +E K +CG ++ F+++ + + ++ V+ I + Sbjct: 112 ------KIKKVGSYFIEVWK---SCGMNMENVQFLWASEEINKKPNEYWSLVLDISRSFN 162 Query: 260 FNQVK---GIFGFTDSDC--IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQD 314 N++K I G ++ + +I +P +Q A IF DI L IDQ Sbjct: 163 INRMKRCLKIMGRSEGEENYCSQILYPCMQCA--------DIFFLNVDICQL---GIDQR 211 Query: 315 PYFRMTRDVAPRIGYPK-PALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVN 373 + R+ K P +L P L Q KMS SD NS+IF+ D+ + K+ Sbjct: 212 KVNMLAREYCDIKKIKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMDDSESDVNRKIK 271 Query: 374 KHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDK---------LEQIRKDYTSGA 424 K + E+ + Y F L +K L+++ DY +G Sbjct: 272 KAYCPP---NVIENNPIYAYAKSIIFPSYNEFNLVRKEKNGGDKTYYTLQELEHDYVNGF 328 Query: 425 MLTGELKKALIEVLQPLIAEHQ 446 + +LK + + L+ + Sbjct: 329 IHPLDLKDNVAMYINKLLQPVR 350 >2J5B-A nrPDB Length = 348 Score = 187 bits (475), Expect = 9e-48, Method: Composition-based stats. Identities = 68/342 (19%), Positives = 143/342 (41%), Gaps = 35/342 (10%) Query: 141 RDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGH-LIPFIFTKWLQDVFNVPLVIQMTDDE 199 ++++ ++ + F Y G PS +H+ LI + T + + ++I + D Sbjct: 26 ETLDRLKQLVDSGRIFTAYNGFEPSGR-IHIAQALITVMNTNNMIECGG-QMIIYIADWF 83 Query: 200 KYLWKDL--TLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKH 257 + + +++ + ACG +++ T +++ + + + ++ I + Sbjct: 84 AKMNLKMNGDINKIRELGRYFIEVFKACGINLDGTRFIWASEFIASNPSYIERMLDIAEF 143 Query: 258 VTFNQVK---GIFGFTDSDC--IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAID 312 T ++VK I G +SDC +I +P +QAA F ++ + DI L ID Sbjct: 144 STISRVKRCCQIMGRNESDCLKASQIFYPCMQAADVF-----ELVPEGIDICQL---GID 195 Query: 313 QDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKV 372 Q + + A G P L +L G + KMS SDP +IF+ DT +++ K+ Sbjct: 196 QRKVNMLAIEYANDRGLKIPISLSHHMLMSLSGPKKKMSKSDPQGAIFMDDTEQEVSEKI 255 Query: 373 NKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDD------DKLEQIRKDYTSGAML 426 ++ + F + ++ L +F + +E I++D++S M Sbjct: 256 SRAYCT--------DETFDNPIFEYIKYLLLRWFGTLNLCGKIYTDIESIQEDFSS--MN 305 Query: 427 TGELKKALIEVLQPLIAEHQAR-RKEVTDEIVKEFMTPRKLS 467 ELK + + +I + +K E++ + ++ S Sbjct: 306 KRELKTDVANYINTIIDLVREHFKKPELSELLSNVKSYQQPS 347 >3P0I-A nrPDB Length = 690 Score = 184 bits (467), Expect = 6e-47, Method: Composition-based stats. Identities = 69/346 (19%), Positives = 125/346 (36%), Gaps = 37/346 (10%) Query: 145 QVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK 204 ++ + E K Y G PS MH+ I V + D + Sbjct: 30 ELRNLIEKKPLIRCYDGFEPSGR-MHIAQGIFKAVNVNKCTAAGCEFVFWVADWFALMND 88 Query: 205 DL--TLDQAYSYAVENAKDIIACGFDINKT-FIFSDLDYMGMSSGFYKNVVKIQKHVTFN 261 + L++ + A G D++K F++S + + +++ V+ I + T Sbjct: 89 KVGGELEKIRIVGRYLIEVWKAAGMDMDKVLFLWSSEEITSHADTYWRMVLDIGRQNTIA 148 Query: 262 QVK---GIFGFTDSD-CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYF 317 ++K I G T+ ++ +P +Q IF + DI L +DQ Sbjct: 149 RIKKCCTIMGKTEGTLTAAQVLYPLMQCC--------DIFFLKADICQL---GLDQRKVN 197 Query: 318 RMTRDVAPRIGYP-KPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHA 376 + R+ IG KP +L L+ Q KMS SDP+S+IF+ DT + + K+ + Sbjct: 198 MLAREYCDLIGRKLKPVILSHHMLAGLKQGQAKMSKSDPDSAIFMEDTEEDVARKIRQAY 257 Query: 377 FSGGRDTIEEHRQFGGNCDVDVSFMYLTFFL---------------EDDDKLEQIRKDYT 421 + + G D L +F E + + + Sbjct: 258 CPRVKQSASAITDDGAPVATDDRNPVLDYFQCVVYARPGAAATIDGTTYATYEDLEQAFV 317 Query: 422 SGAMLTGELKKALIEVLQPLIAEHQAR--RKEVTDEIVKEFMTPRK 465 S + LK LI+ + L+ + E E+++ + RK Sbjct: 318 SDEVSEDALKSCLIDEVNALLEPVRQHFASNEEAHELLEAVKSYRK 363 Score = 64.8 bits (156), Expect = 7e-11, Method: Composition-based stats. Identities = 96/503 (19%), Positives = 173/503 (34%), Gaps = 102/503 (20%) Query: 22 LVRSLKAGNA--SKDEIDSAVKMLVSLKMSYKAAAGEDYKADCP---PGNPAPTSNHGPD 76 ++ LK G A SK + DSA+ M + + + A + +A CP A T + P Sbjct: 220 MLAGLKQGQAKMSKSDPDSAIFM----EDTEEDVARKIRQAYCPRVKQSASAITDDGAPV 275 Query: 77 ATEAEEDFVDPWT----VQTSSAKGID------YDKLIVRFGSSKIDKELINR--IERAT 124 AT+ +D + + +A ID Y+ L F S ++ ++ + I+ Sbjct: 276 ATDDRNPVLDYFQCVVYARPGAAATIDGTTYATYEDLEQAFVSDEVSEDALKSCLIDEVN 335 Query: 125 GQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRG-PSSEAMHVGHLIPFIFTKWL 183 R F S+ + +++L+A ++ + G P +E W+ Sbjct: 336 ALLEPV---RQHFASNEEAHELLEAVKSYRK----DGATLPLAETALPAAPAKPHACMWM 388 Query: 184 QDVFNVPL-----VIQMTDDEKYLWKDLTLDQA----YSYAVENA----KDIIAC----- 225 + VPL +I++T D + T+ + A + KDI A Sbjct: 389 PALLKVPLDVAEGMIKVTKDFIAAHPEGTVTLVLPDWSAVASDEITGVEKDISAALQVNC 448 Query: 226 ------GFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKIS 279 G + + + +G F+ +V+ I + + V+ ++G + G++ Sbjct: 449 ALLKAYGLPSSVKIVTENEVILGNCDDFWVSVIGIARKNLLSHVEELYG-GEVRNAGQVI 507 Query: 280 FPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTF 339 ++ A + S + D Y + D + PAL Sbjct: 508 AALMRVATALMLSVSHVISTSLDGHINAFA----REYTKERIDCVQTLEGRIPALHRPGA 563 Query: 340 FPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSG------------------GR 381 PA+ GA + ++L D I+ K+ K + G Sbjct: 564 APAVLGA---------DDVLYLDDNDMDIRRKIKKAYSAPNEEANPVISVAQHLLAQHGA 614 Query: 382 DTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPL 441 +IE GGN + E + D SGA+ +LK A VLQ L Sbjct: 615 LSIERGEANGGNVSYNTP--------------EALVADCGSGALHPADLKAA---VLQLL 657 Query: 442 IAEHQARRKEVTDEIVKEFMTPR 464 + R + E+ K R Sbjct: 658 LDRSAQARALLNGELKKNMTVLR 680 >5DK4-A nrPDB Length = 329 Score = 176 bits (446), Expect = 2e-44, Method: Composition-based stats. Identities = 69/320 (21%), Positives = 124/320 (38%), Gaps = 37/320 (11%) Query: 157 YLYTGRGPSSEAMHVGHLIPFI-FTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 +++G PS + +G+ I + LQ +N I D+ + + Sbjct: 4 TIFSGIQPSG-VITIGNYIGALRQFVELQHEYNCYFCIV---DQHAITVWQDPHELRQNI 59 Query: 216 VENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSD 273 A +A G D + FI S++ ++ + +V I + Q K ++ Sbjct: 60 RRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQFKEKSAGKEAV 119 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPK 331 G +++P + AA I TDI +P DQ + +TRD+A R Y + Sbjct: 120 SAGLLTYPPLMAA--------DILLYNTDI---VPVGEDQKQHIELTRDLAERFNKRYGE 168 Query: 332 PALLHSTFFP-------ALQGAQTKMSASDPNSSIFLT--DTAKQIKTKVNKHAFSGGRD 382 + P +L KMS SDPN ++T D AK I+ K+ K A + Sbjct: 169 LFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKI-KSAVTDSEG 227 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSG--AMLTGELKKALIEVLQP 440 TI ++ +S + + +E++ + Y + +L + +IE L+P Sbjct: 228 TI----RYDKEAKPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRP 283 Query: 441 LIAE-HQARRKEVTDEIVKE 459 + H E D ++ E Sbjct: 284 IQERYHHWMESEELDRVLDE 303 >2CYC-A nrPDB Length = 375 Score = 164 bits (414), Expect = 1e-40, Method: Composition-based stats. Identities = 76/358 (21%), Positives = 125/358 (34%), Gaps = 87/358 (24%) Query: 149 AYENKKPFYLYTGRGPSSEAMHVGH-LIPFIFTKWLQDVF---NVPLVIQMTDDEKYLWK 204 +E P Y G S +H+G L+ Q V L + L Sbjct: 27 LFEIGAPLQHYIGFEISG-YIHLGTGLMAGAKIADFQKAGIKTRVFLADWHSWINDKLGG 85 Query: 205 DLTLDQAYSYAVENA---KDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFN 261 DL + Q + K I G D K + + +++ V+ I K+VT + Sbjct: 86 DLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEIL-EKGDYWQTVIDISKNVTLS 144 Query: 262 QVK---GIFGFTDSDCI--GKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPY 316 +V I G + I K+ +P +Q A F + +DQ Sbjct: 145 RVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQGV-----------TIAHAGMDQRKA 193 Query: 317 FRMTRDVAPRIGYP---------KPALLHSTFFPALQ----------------GAQTKMS 351 + +VA ++ Y KP +H LQ AQ KMS Sbjct: 194 HVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESEEEFKEIKAQMKMS 253 Query: 352 ASDPNSSIFLTDTAKQIKTKVNKHAFSGGRD----------------------TIEEHRQ 389 S P S++F+ D+ ++I+ K+ K AF R+ T+ + Sbjct: 254 KSKPYSAVFIHDSPEEIRQKLRK-AFCPAREVRYNPVLDWVEYIIFREEPTEFTVHRPAK 312 Query: 390 FGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQA 447 FGG+ Y TF E++++D+ G + +LK A+ E L L+ + Sbjct: 313 FGGDV------TYTTF--------EELKRDFAEGKLHPLDLKNAVAEYLINLLEPIRR 356 >5NSF-B nrPDB Length = 318 Score = 151 bits (380), Expect = 8e-37, Method: Composition-based stats. Identities = 57/327 (17%), Positives = 117/327 (35%), Gaps = 50/327 (15%) Query: 137 FFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMT 196 S ++ +VL E G PS + +H+GH + LQ+ ++I + Sbjct: 26 IISEEELREVLKKDEKSAG----IGFEPSGK-IHLGHYLQIKKMIDLQNA-GFDIIIWLA 79 Query: 197 DDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQK 256 D YL + LD+ N K A G + + + NV ++ Sbjct: 80 DLGAYLNQKGELDEIRKIGDYNKKVFEAMGLKAK----YVYGSEHNLDKDYTLNVYRLAL 135 Query: 257 HVTFNQVKGIFGF----TDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAID 312 T + + ++ + ++ +P +Q N + ++ Sbjct: 136 KTTLKRARRSMELIAREDENPKVAEVIYPIMQVNAIHYNGVD-----------VAVGGME 184 Query: 313 QDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKV 372 Q + R++ P+ K +H+ L G + KMS+S N I + D+ ++I+ K+ Sbjct: 185 QRKIHMLARELLPK----KVVCIHNPVLTGLDG-EGKMSSSKGN-FIAVDDSPEEIRAKI 238 Query: 373 NKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDD-----------DKLEQIRKDYT 421 K G GN ++++ +L + L + E++ + Sbjct: 239 KKAYCPAG--------VVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFK 290 Query: 422 SGAMLTGELKKALIEVLQPLIAEHQAR 448 + + LK A+ E L ++ + R Sbjct: 291 NKELHPMRLKNAVAEELIKILEPIRKR 317 >2EL7-A nrPDB Length = 337 Score = 151 bits (380), Expect = 1e-36, Method: Composition-based stats. Identities = 65/318 (20%), Positives = 119/318 (37%), Gaps = 33/318 (10%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKW--LQDVFNVPLVIQMTDDEKYLWK-DLTLDQAYSY 214 + +G PS E +H+G+ + I +W + + + D Sbjct: 4 VLSGIQPSGE-IHIGNYLGAIK-QWVAIGEKLGRDAFFCIVDYHALTNPLAYDPSTLAQR 61 Query: 215 AVENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDS 272 E A IA G D K F+ S + S + + + Q K ++ Sbjct: 62 TFEAALVNIAAGLDPEKVTLFVQSHVPEHTELSWVFTTLTPLGDLTRMTQFKDKASKQET 121 Query: 273 DCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG---- 328 G + +P +QAA I + D +P DQ + +TR++A R Sbjct: 122 VWSGLLMYPVLQAA--------DILIYKADT---VPVGEDQVQHIELTREIARRFNHLFG 170 Query: 329 --YPKPALLHSTFFPALQG--AQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTI 384 +P+P L + P + G + KMS S N+ I L + + I K+ R + Sbjct: 171 ETFPEPQALLNPEAPRVPGIDGKAKMSKSLGNT-IGLLEPEESIWQKIQHLPDDPQRIRL 229 Query: 385 EEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAE 444 + G+ + + F YL++F D +E ++++Y + T +K+ L + L + Sbjct: 230 SDP----GDPERTILFTYLSYFAPKDL-VEALKEEYRKAGVGTYVVKRILFDHLMEALRP 284 Query: 445 HQARRKEVTDEIVKEFMT 462 + R E + M Sbjct: 285 IRE-RAEALKKDPDYVMD 301 >3PRH-A nrPDB Length = 388 Score = 146 bits (368), Expect = 2e-35, Method: Composition-based stats. Identities = 66/320 (20%), Positives = 118/320 (36%), Gaps = 37/320 (11%) Query: 157 YLYTGRGPSSEAMHVGHLIPFIFT-KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 +++G PS ++ +G+ I + LQ +N I D L+ Sbjct: 37 TIFSGIQPSG-SVTLGNYIGAMKQFVELQHDYNSYFCI--VDQHAITVPQDRLE-LRKNI 92 Query: 216 VENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSD 273 A +A G D K FI S++ + + V I + Q K ++ Sbjct: 93 RNLAALYLAVGLDPEKATLFIQSEVPAHAQAGWMMQCVAYIGELERMTQFKDKSKGNEAV 152 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPA 333 G +++P + AA I TD L+P DQ + +TR++A R Sbjct: 153 VSGLLTYPPLMAA--------DILLYGTD---LVPPGEDQKQHLELTRNLAERFNKKYND 201 Query: 334 LLHST---------FFPALQGAQTKMSASDPNSSIFLT--DTAKQIKTKVNKHAFSGGRD 382 + +L KMS SDPN ++T D KQ++ K+ K A + Sbjct: 202 IFTIPEVKIPKVGARIMSLNDPLKKMSKSDPNQKAYITLLDEPKQLEKKI-KSAVTDSEG 260 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAM--LTGELKKALIEVLQP 440 + +F VS + + + + +E++ Y G+L + ++ L+P Sbjct: 261 IV----KFDKENKPGVSNLLTIYSILGNTTIEELEAKYEGKGYGEFKGDLAEVVVNALKP 316 Query: 441 LIAEHQAR-RKEVTDEIVKE 459 + + E D I+ E Sbjct: 317 IQDRYYELIESEELDRILDE 336 >3U1V-A nrPDB Length = 338 Score = 146 bits (367), Expect = 3e-35, Method: Composition-based stats. Identities = 63/320 (19%), Positives = 117/320 (36%), Gaps = 37/320 (11%) Query: 157 YLYTGRGPSSEAMHVGHLIPFI-FTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 +++ P+ + +G I + LQ +N I D+ + + Sbjct: 3 TIFSAICPTG-VITIGRYIGALRQFVELQHEYNCYFCIA---DQSAITVWQDPHELRQNI 58 Query: 216 VENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSD 273 A +A G D + FI S++ ++ + +V I + K + ++ Sbjct: 59 RRLAALYLAVGIDPTQATLFIASEVPAHAQAAWMLQCIVYIGELERMTLFKELSAGKEAV 118 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPK 331 G ++ P I AA I TDI +P + +TRD+A R Y + Sbjct: 119 SAGLLTHPPIYAA--------MILLYNTDI---VPVGEYGKQLYELTRDLAERFNKRYGE 167 Query: 332 PALLHSTFFP-------ALQGAQTKMSASDPNSSIFLT--DTAKQIKTKVNKHAFSGGRD 382 + P +L M SDPN ++T D AK I+ K+ K A + Sbjct: 168 LFTIPEARIPKVGARIMSLVDPTKSMYQSDPNPKAYITLLDDAKTIEKKI-KSAVTDSEG 226 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSG--AMLTGELKKALIEVLQP 440 TI ++ +S + + +E++ + Y + +L + +IE L+P Sbjct: 227 TI----RYDKEAKPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRP 282 Query: 441 LIAE-HQARRKEVTDEIVKE 459 + H E D ++ E Sbjct: 283 IQERYHHWMESEELDRVLDE 302 >2DLC-X nrPDB Length = 394 Score = 131 bits (330), Expect = 6e-31, Method: Composition-based stats. Identities = 67/328 (20%), Positives = 119/328 (36%), Gaps = 43/328 (13%) Query: 146 VLDAYE-NKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK 204 + D E K+ LY G P+ H G+ +P + + + D +L Sbjct: 29 IKDVLEVQKRHLKLYWGTAPTGRP-HCGYFVPMTKLADFLKA-GCEVTVLLADLHAFLDN 86 Query: 205 DLTLDQAYSY---AVEN-AKDII-ACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVT 259 + +Y E K I+ + I K Y ++ + ++ ++ V+ Sbjct: 87 MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQ-LTPDYTMDIFRLSNIVS 145 Query: 260 FNQVKG----IFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDP 315 N K + + + + +P +QA D+ C +DQ Sbjct: 146 QNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF----------LDVDCQF-GGVDQRK 194 Query: 316 YFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKH 375 F + + P +GY K A L + P L KMSASDPNS I L + KQ+K K+N Sbjct: 195 IFVLAEENLPSLGYKKRAHLMNPMVPGLAQG-GKMSASDPNSKIDLLEEPKQVKKKINSA 253 Query: 376 AFSGGRDTIEEHRQFGGNCDVDVSFMYL-------TFFLEDDDK---------LEQIRKD 419 S G +EE+ V L FF++ +K E+++ Sbjct: 254 FCSPG--NVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLA 311 Query: 420 YTSGAMLTGELKKALIEVLQPLIAEHQA 447 + + +LK + + + L+ + Sbjct: 312 FKEEKLSPPDLKIGVADAINELLEPIRQ 339 >5V0I-A nrPDB Length = 337 Score = 128 bits (321), Expect = 6e-30, Method: Composition-based stats. Identities = 56/313 (17%), Positives = 110/313 (35%), Gaps = 35/313 (11%) Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 +++G PS E + +G+ + + +W+ + + + D + + + Sbjct: 8 IVFSGAQPSGE-LTIGNYMGALR-QWVNMQDDYHCIYCIVDQHAITVRQDA-QKLRKATL 64 Query: 217 ENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFG-FTDSD 273 + +ACG D K+ F+ S + + Q K + ++ Sbjct: 65 DTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSARYAENI 124 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPK 331 G +P + AA I +T+ L+P DQ + ++RD+A R Y Sbjct: 125 NAGLFDYPVLMAA--------DILLYQTN---LVPVGEDQKQHLELSRDIAQRFNALYGD 173 Query: 332 PALLHSTFFP-------ALQGAQTKMSASDP--NSSIFLTDTAKQIKTKVNKHAFSGGRD 382 + F P +L KMS SD N+ I L + K + K+ + Sbjct: 174 IFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEP 233 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAM---LTGELKKALIEVLQ 439 + ++ VS + + ++ K + G M L GE+ A+ +L Sbjct: 234 PV---VRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFE-GKMYGHLKGEVADAVSGMLT 289 Query: 440 PLIAEHQARRKEV 452 L + R + Sbjct: 290 ELQERYHRFRNDE 302 >3N9I-A nrPDB Length = 346 Score = 124 bits (312), Expect = 7e-29, Method: Composition-based stats. Identities = 57/306 (18%), Positives = 109/306 (35%), Gaps = 33/306 (10%) Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 +++G PS E + +G+ + + +W+Q + + + D + + Sbjct: 17 IVFSGAQPSGE-LTIGNYMGALR-QWVQMQDDYDCIYCIVDLHAITARQ-DPALLRKRTL 73 Query: 217 ENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFG-FTDSD 273 + +ACG D K+ F+ S + S + Q K + ++ Sbjct: 74 DTLALYLACGIDPKKSTIFVQSHVPEHSQLSWALNCYTYFGELSRMTQFKDKSARYAENI 133 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPK 331 G +P + AA Q +P DQ + ++RD+A R Y Sbjct: 134 NAGLFDYPVLMAADILLYQTNQ-----------VPVGEDQKQHLELSRDIASRFNNLYGD 182 Query: 332 PALLHSTFFP-------ALQGAQTKMSASDP--NSSIFLTDTAKQIKTKVNKHAFSGGRD 382 + F P +LQ KMS SD N+ I L + K + K+ + Sbjct: 183 IFKIPEPFIPKAGARVMSLQDPTKKMSKSDDNRNNVIELLEDPKSVVKKIKRAMTDSDEP 242 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLI 442 + ++ VS + + ++ +T G M G LK A+ + + ++ Sbjct: 243 AL---IRYDVEKKAGVSNLLDILSGVTGQSIPELEAQFT-GQMY-GHLKGAVADAVSGML 297 Query: 443 AEHQAR 448 +E Q R Sbjct: 298 SELQER 303 >6DFU-A nrPDB Length = 337 Score = 124 bits (310), Expect = 1e-28, Method: Composition-based stats. Identities = 56/306 (18%), Positives = 110/306 (35%), Gaps = 33/306 (10%) Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 +++G PS E + +G+ + + W++ + + + D + + + Sbjct: 8 IVFSGVQPSGE-LTIGNYLGALRN-WVKMQEDYECIFCVVDLHAITVRQDPVA-LRKATL 64 Query: 217 ENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFG-FTDSD 273 + +ACG D NK+ F+ S + S + Q K + ++ Sbjct: 65 DVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENI 124 Query: 274 CIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG----- 328 +G +P + AA +P DQ + +TRD+A R Sbjct: 125 NVGLFDYPVLMAADILLYQAKS-----------VPVGDDQKQHLEITRDIANRFNALYGN 173 Query: 329 -YPKPALLHST---FFPALQGAQTKMSASDP--NSSIFLTDTAKQIKTKVNKHAFSGGRD 382 + P + +LQ + KMS SD N+ + L + K + K+ + Sbjct: 174 IFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEP 233 Query: 383 TIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLI 442 + ++ VS + D + + K++ G M G LK A+ + + L+ Sbjct: 234 PV---VRYDVQNKAGVSNLLDILSAVTDKPIADLEKEFE-GKMY-GHLKTAVADEVSTLL 288 Query: 443 AEHQAR 448 A Q R Sbjct: 289 ASLQER 294 >3SZ3-A nrPDB Length = 341 Score = 121 bits (303), Expect = 8e-28, Method: Composition-based stats. Identities = 57/316 (18%), Positives = 112/316 (35%), Gaps = 43/316 (13%) Query: 157 YLYTGRGPSSEAMHVGHLIPFI-FTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYA 215 + +G PS E + +G+ + + + +QD ++ + D + + Sbjct: 8 IVLSGVQPSGE-LSIGNYLGALRQWQQMQDDYDCQYCV--VDLHAITVRQ-DPQALHEAT 63 Query: 216 VENAKDIIACGFDINKT--FIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFG-FTDS 272 ++ +A G D K+ F+ S + ++ + Q K + + Sbjct: 64 LDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYAND 123 Query: 273 DCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGY--- 329 G +P + AA I +P DQ + + RD+A R Sbjct: 124 VNAGLFGYPVLMAA--------DILLYGAH---QVPVGSDQKQHLELARDIATRFNNIYS 172 Query: 330 -PKPA-LLHSTFFP-------ALQGAQTKMSASDPN--SSIFLTDTAKQIKTKVNKHAFS 378 +P + + P +LQ A KMS SD N + I L + K I K+NK Sbjct: 173 PEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSIIKKINKAQTD 232 Query: 379 GGRDTIEEHRQFGGNCD--VDVSFMYLTFFLEDDDKLEQIRKDYTSGAM---LTGELKKA 433 E + + + ++ + + +I Y M ++ +A Sbjct: 233 -----AETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEA 287 Query: 434 LIEVLQPLIAEHQARR 449 ++ +L+P+ AE+Q R Sbjct: 288 VVAMLEPVQAEYQRIR 303 >5EKD-A nrPDB Length = 343 Score = 111 bits (277), Expect = 8e-25, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 124/327 (37%), Gaps = 44/327 (13%) Query: 149 AYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT-KWLQDVFNVPLVIQMTDDEKYLWKDLT 207 A + +++G P+ +H+G+ + I + LQD ++ L + D +T Sbjct: 11 ALQKDSKKRVFSGIQPTG-ILHLGNYLGAIESWVRLQDEYDSVLY-SIVD-----LHSIT 63 Query: 208 LDQAYSYAVENAKDI----IACGFDINKTFIFSDLD--YMGMSSGFYKNVVKIQKHVTFN 261 + Q + ++ D+ +ACG + K+ +F S +V++ + + Sbjct: 64 VPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLH 123 Query: 262 QVKGIFGF-TDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMT 320 Q K +G +++P +QAA +P DQ + + Sbjct: 124 QWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTH-----------VPVGEDQVQHMELV 172 Query: 321 RDVAPRIG------YPKPALLHSTF--FPALQGAQTKMSASDPN--SSIFLTDTAKQIKT 370 +D+A +P P + ++ +L+ KMS SDP+ +++ +TD+ ++I Sbjct: 173 QDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQ 232 Query: 371 KVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGEL 430 K K + + G VS + +E++ + S M T Sbjct: 233 KFRKAVTDFTSEVTYDPAGRAG-----VSNIVAVHAAVTGLSVEEVVR--RSAGMNTARY 285 Query: 431 KKALIE-VLQPLIAEHQARRKEVTDEI 456 K A+ + V++ + K D+ Sbjct: 286 KLAVADAVIEKFAPIKREIEKLKLDKD 312 >6MTK-A nrPDB Length = 329 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 111/311 (35%), Gaps = 50/311 (16%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDL-------TLDQ 210 + TG + H+G+L+ I + + L + +D + +L Q Sbjct: 11 ILTGIQATGTP-HLGNLLGAI-------IPAIELAKKPENDSLFFIANLHTLTQIKDAAQ 62 Query: 211 AYSYAVENAKDIIACGFDINKTFIF--SDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFG 268 E A +ACG D KT + SD+ + + Q+ + K Sbjct: 63 LRQNTYEIAAAWLACGLDTEKTIFYRQSDIPETCELTWYLDCFFPFQRLTLAHSFKDKAD 122 Query: 269 FTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG 328 G ++P + AA I ++ +P DQ + +TRDVA + Sbjct: 123 RLQDVNAGLFNYPILMAA--------DILLYDAEV---VPVGKDQLQHLEITRDVAEKFN 171 Query: 329 YPKPALL---------HSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSG 379 + + + P G KMS S N I + K++K ++ Sbjct: 172 RQMGEVFVLPGAEIQESTKYVPGTDG--HKMSKSRGN-IINIFLPEKELKKQIMSIESD- 227 Query: 380 GRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQ 439 ++EE + + + D +F+ + + ++ E +R+ Y +G G K E+L Sbjct: 228 -SKSLEEPK----DPETDKTFI-IYALIATPEQTEALRQKYLAGNFGYGHAKT---ELLN 278 Query: 440 PLIAEHQARRK 450 ++ R+ Sbjct: 279 LILERFAKERE 289 >2YY5-A nrPDB Length = 348 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 62/325 (19%), Positives = 118/325 (36%), Gaps = 44/325 (13%) Query: 159 YTGRGPSSEAMHVGHLIPFIF-TKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVE 217 TG S + H+G+ + + LQ+ L + + D D + Sbjct: 8 LTGIQASGKQ-HLGNYLGVMQSLIELQE--QCQLFVFVADLHSITV-DFQPQALKQNNFD 63 Query: 218 NAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVV-----KIQKHVTFNQVKGIFGFTDS 272 + ++A G D K +F D + S Y +V ++Q+ F K + Sbjct: 64 LVRTLLAVGLDPQKACLFLQSDLLEHSMMGYLMMVQSNLGELQRMTQFKAKKAEQTRNPN 123 Query: 273 DCI----GKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPR-- 326 + G +++PA+ A I + DI +P DQ + +TRD+A R Sbjct: 124 GTLNIPTGLLTYPALMA--------GDILLYQPDI---VPVGNDQKQHLELTRDLAQRIQ 172 Query: 327 ----IGYPKPALLHST---FFPALQGAQTKMSASD--PNSSIFLTDTAKQIKTKVNKHAF 377 + P + + L KMS S N I+L D + + K+ + A Sbjct: 173 KKFKLKLRLPQFVQNKDTNRIMDLFDPTKKMSKSSKNQNGVIYLDDPKEVVVKKIRQ-AT 231 Query: 378 SGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKL-----EQIRKDYTSGAMLTGELKK 432 + + I + ++ + + L + +++ + L +LK Sbjct: 232 TDSFNKIRFASKTQPGVTNMLTILKALLKEPVNQSLTNQLGNDLEAYFSTKSYL--DLKN 289 Query: 433 ALIEVLQPLIAEHQARRKEVTDEIV 457 AL E L+ Q +R++++ E V Sbjct: 290 ALTEATVNLLVNIQRKREQISREQV 314 >3TZL-A nrPDB Length = 322 Score = 101 bits (252), Expect = 5e-22, Method: Composition-based stats. Identities = 51/308 (16%), Positives = 111/308 (36%), Gaps = 33/308 (10%) Query: 158 LYTGRGPSSEAMHVGHLIPFIFTK-WLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 + TG PS + +H+G+ I Q+ + + + + ++ ++ Sbjct: 6 VLTGLQPSGD-LHIGNYFGAIKQMVDAQE--KSQMFMFIANYHAMTSSQDG-EKLKQNSL 61 Query: 217 ENAKDIIACGFDINKTFIF--SDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDC 274 + A ++ G D K+ + SD+ + + + K S Sbjct: 62 KAAAAFLSLGIDPQKSVFWLQSDVKEVMELYWILSQFTPMGLLERAHSYKDKVAKGLSAS 121 Query: 275 IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG------ 328 G S+P + AA ++P DQ + + RD+A ++ Sbjct: 122 HGLFSYPVLMAADILLFDTR-----------IVPVGKDQIQHVEIARDIALKVNNEWGEI 170 Query: 329 YPKPALLHSTFFPALQGAQT-KMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEH 387 + P + + G KMS S ++I + + K +K +++ T E Sbjct: 171 FTLPEARVNEEVAVVVGTDGAKMSKS-YQNTIDIFSSEKTLKKQISSIVTD---STALED 226 Query: 388 RQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQA 447 + NC++ F FL++ + ++++ Y G G K L E++ E + Sbjct: 227 PKDHENCNI---FKIAKLFLDESGQ-KELQIRYEKGGEGYGHFKIYLNELVNAYFKEARE 282 Query: 448 RRKEVTDE 455 + E+ ++ Sbjct: 283 KYNELLEK 290 >4Q93-A nrPDB Length = 372 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 63/338 (18%), Positives = 114/338 (33%), Gaps = 41/338 (12%) Query: 130 HFLRRGI--FFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVF 187 H + R + + ++L ++ +Y G + + HV + +P Sbjct: 12 HLITRNLQEVLGEEKLKEIL----KERELKIYWGTATTGKP-HVAYFVPMSKIADFLKA- 65 Query: 188 NVPLVIQMTDDEKYLWKDLTLDQA----YSYAVENAKDII-ACGFDINKTFIFSDLDYMG 242 + I D YL + SY K ++ + G + K DY Sbjct: 66 GCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQ- 124 Query: 243 MSSGFYKNVVKIQKHVTFNQVK----GIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFR 298 +S + +V ++ VT + K + + + + +P +QA F Sbjct: 125 LSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQF- 183 Query: 299 DRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSS 358 IDQ F P +GY K L + P L G+ KMS+S+ S Sbjct: 184 ----------GGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGS--KMSSSEEESK 231 Query: 359 IFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDD------- 411 I L D + +K K+ K G +E + V L D+ Sbjct: 232 IDLLDRKEDVKKKLKKAFCEPG--NVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTY 289 Query: 412 -KLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQAR 448 + KD+ + + G+LK ++ L L+ + + Sbjct: 290 TAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREK 327 >5TEW-A nrPDB Length = 344 Score = 85.6 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 56/305 (18%), Positives = 99/305 (32%), Gaps = 44/305 (14%) Query: 170 HVGHLIPFIF-TKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFD 228 H+G+ + I + + + D + K + + A +ACG D Sbjct: 25 HLGNYVGAIRPAVRAAQNPDTESFLFLADYHG-IIKCHEQEMIHQSTQAVAATWLACGLD 83 Query: 229 INKTFIF--SDLDYMGMSSGFYKNVV---KIQKHVTFN---QVKGIFGFTDSD---CIGK 277 +T + SD+ + + + + + + Q G D D +G Sbjct: 84 PERTTFYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGL 143 Query: 278 ISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIG--YPKPALL 335 S+P + A + + +P DQ + M RD+A R + + L Sbjct: 144 FSYPILMTADILMFNANE-----------VPVGRDQIQHVEMARDIAGRFNHRFQELFTL 192 Query: 336 HS-------TFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHR 388 L G KMS S N+ I L + K+ + VNK ++E Sbjct: 193 PEVKIDENVELLVGLDG--RKMSKSYGNT-IPLWENDKKTQKSVNKIIT-----NMKEPG 244 Query: 389 QFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQAR 448 + D F F + E + + GE KK + +AE + R Sbjct: 245 E-PKQPDESPLFEIYKAFSTPSETAE--FTQMLADGLAWGEAKKLSAAKINAELAELRER 301 Query: 449 RKEVT 453 +T Sbjct: 302 YNALT 306 >6OTJ-A nrPDB Length = 439 Score = 81.3 bits (199), Expect = 9e-16, Method: Composition-based stats. Identities = 60/324 (18%), Positives = 118/324 (36%), Gaps = 39/324 (12%) Query: 133 RRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLV 192 RG+ D+ + LDA N++ LY G P+++++H+GHL+P + + Q + P+ Sbjct: 17 SRGLIAQTTDI-EALDALLNEQKIALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIA 75 Query: 193 IQ-----MTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGF 247 + M D + + +L+ A V I +F + M ++ + Sbjct: 76 LVGGATGMIGDPSFKAAERSLNSAE--TVAGWVGSIRSQLTPFLSFEGGNAAIMANNADW 133 Query: 248 YKNV------VKIQKHVTFNQV---KGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFR 298 + ++ I KH + N + + + D D G ISF + A S + Sbjct: 134 FGSMNCLDFLRDIGKHFSVNAMLNKESVKQRIDRDGAG-ISF--TEFAYSLLQGYDFAEL 190 Query: 299 DRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSS 358 ++ L DQ D+ R+ + L G TK ++ + Sbjct: 191 NKRHGAVLEIGGSDQWGNITAGIDLTRRLNQKQVFGLTLPLVTKSDG--TKFGKTEGG-A 247 Query: 359 IFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRK 418 ++L K + + F + + DV Y TF ++ + + + Sbjct: 248 VWLN------AKKTSPYQF-------YQFWLKVADADVYKFLKYFTFLSIEEIGVVEAKD 294 Query: 419 DYTSGAMLTGELKKALIEVLQPLI 442 + E ++ L E + LI Sbjct: 295 KASGSK---PEAQRILAEEMTRLI 315 >1JIJ-A nrPDB Length = 420 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 59/325 (18%), Positives = 116/325 (35%), Gaps = 45/325 (13%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ + D + D NK+ LY G P+++++H+GHL+PF+ + Q+ + P+V+ Sbjct: 12 RGLIYQQTDEQGIEDLL-NKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVL 70 Query: 194 Q-----MTDD------EKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 M D E+ L + +D+ + +I G D + + ++ D++G Sbjct: 71 IGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTD-HGAVLVNNRDWLG 129 Query: 243 MSSGFYKNVVKIQKHVTFNQVKGI----FGFTDSDCIGKISFPAIQAAPSFSNSFPQIFR 298 + KHV N + G + ++ +QA Sbjct: 130 QI-SLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQA--------IDFGH 180 Query: 299 DRTDIQCLIPC-AIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNS 357 ++ C I DQ ++ R+ Y + + P + + K + Sbjct: 181 LNRELNCKIQVGGSDQWGNITSGIELMRRM-YGQTDA-YGLTIPLVTKSDGKKFGKSESG 238 Query: 358 SIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIR 417 +++L D K + E QF N + +L +F + Sbjct: 239 AVWL-DAEKT---------------SPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRL 282 Query: 418 KDYTSGAMLTGELKKALIEVLQPLI 442 + + A E +K L E + I Sbjct: 283 EQSKNEAPHLREAQKTLAEEVTKFI 307 >3TS1-A nrPDB Length = 419 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 60/339 (17%), Positives = 116/339 (34%), Gaps = 52/339 (15%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D + L N++ LY G P+++++H+GHL + + Q + P+ + Sbjct: 10 RGLVNQTTDEDG-LRKLLNEERVTLYCGFDPTADSLHIGHLATILTMRRFQQAGHRPIAL 68 Query: 194 ------QMTD-----DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 + D E+ L T++ + E + D N I ++ D++G Sbjct: 69 VGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIG 128 Query: 243 MSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG----KISFPAIQAAPSFSNSFPQIFR 298 + + KH + N + G + S+ +QA + + Sbjct: 129 -PLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQA-------YDFLRL 180 Query: 299 DRTDIQCLIPCAIDQ----DPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASD 354 T+ L DQ + R G + L G + + S Sbjct: 181 YETEGCRLQIGGSDQWGNITAGLELIR---KTKGEARAFGLTIPLVTKADGTKFGKTES- 236 Query: 355 PNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFL-EDDDKL 413 +I+L K K + + F QF N D YL +F +++ Sbjct: 237 --GTIWLD------KEKTSPYEF----------YQFWINTDDRDVIRYLKYFTFLSKEEI 278 Query: 414 EQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEV 452 E + ++ +K L E + L+ +A R+ + Sbjct: 279 EALEQELREAP-EKRAAQKTLAEEVTKLVHGEEALRQAI 316 >1TYB-E nrPDB Length = 319 Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 60/339 (17%), Positives = 116/339 (34%), Gaps = 52/339 (15%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D + L N++ LY G P+++++H+GHL + + Q + P+ + Sbjct: 10 RGLVNQTTDEDG-LRKLLNEERVTLYCGFDPTADSLHIGHLAGILTMRRFQQAGHRPIAL 68 Query: 194 ------QMTD-----DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 + D E+ L T++ + E + D N I ++ D++G Sbjct: 69 VGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIG 128 Query: 243 MSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG----KISFPAIQAAPSFSNSFPQIFR 298 + + KH + N + G + S+ +QA + + Sbjct: 129 -PLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQA-------YDFLRL 180 Query: 299 DRTDIQCLIPCAIDQ----DPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASD 354 T+ L DQ + R G + L G + + S Sbjct: 181 YETEGCRLQIGGSDQWGNITAGLELIR---KTKGEARAFGLTIPLVTKADGTKFGKTES- 236 Query: 355 PNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFL-EDDDKL 413 +I+L K K + + F QF N D YL +F +++ Sbjct: 237 --GTIWLD------KEKTSPYEF----------YQFWINTDDRDVIRYLKYFTFLSKEEI 278 Query: 414 EQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEV 452 E + ++ +K L E + L+ +A R+ + Sbjct: 279 EALEQELREAP-EKRAAQKTLAEEVTKLVHGEEALRQAI 316 >6BQZ-A nrPDB Length = 408 Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 58/326 (17%), Positives = 109/326 (33%), Gaps = 54/326 (16%) Query: 131 FLRRGI--FFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQD--- 185 ++RG S D+ L + +P + G P++ +H+GH + K QD Sbjct: 17 LIQRGTHEIISEEDL---LKKLKENRPLKIKAGFDPTAPDLHLGHTVLINKLKTFQDLGH 73 Query: 186 --VFNVPLVIQMTDD---EKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 240 F + M D + L+ +Q + A + + D NKT + + ++ Sbjct: 74 EVTFLIGDYTAMIGDPTGKSATRPPLSREQVEANAKTYQEQVFKI-LDPNKTKVRFNSEW 132 Query: 241 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDC------IGKISFPAIQAAPSFSNSFP 294 S +++++ T +++ FT I + +P +Q S + Sbjct: 133 FNQKSA--ADLIQLASQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQGYDSIALEAD 190 Query: 295 QIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASD 354 + DQ M R + R G + L G KMS S Sbjct: 191 -----------VELGGTDQTFNLLMGRTLQSRYGQESQVCITVPILEGLDGVN-KMSKSL 238 Query: 355 PNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLE 414 N I + D + KV + ++ F L+F D +++ Sbjct: 239 GN-YIGVFDAPGAMYQKVLSMP----------------DSLIERYFDLLSFKSLD--EIK 279 Query: 415 QIRKDYTSGAMLTGELKKALIEVLQP 440 + + +G E+K+ L L Sbjct: 280 ALLDEIAAGR-NPQEVKRILALELVE 304 >2JAN-A nrPDB Length = 432 Score = 72.5 bits (176), Expect = 4e-13, Method: Composition-based stats. Identities = 48/249 (19%), Positives = 91/249 (36%), Gaps = 36/249 (14%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D++ + + P +Y G P++ ++H GHL+P + + Q + P+V+ Sbjct: 12 RGLIAQSTDLDTLAAEAQRG-PMTVYAGFDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVL 70 Query: 194 Q-----MTDD-----EKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGM 243 M D E+ L + T+ + + + + ++L++ G Sbjct: 71 AGGATGMIGDPRDVGERSLNEADTVAEWTERIRGQLERFVDFDDSPMGAIVENNLEWTGS 130 Query: 244 SSGFYKNVVKIQKHVTFNQVKG---IFGFTDSDCIGK--ISFPAIQAAPSFSNSFPQIFR 298 S + + I KH + N + I + I S+ +QA + Sbjct: 131 LSA-IEFLRDIGKHFSVNVMLARDTIRRRLAGEGISYTEFSYLLLQAND-------YVEL 182 Query: 299 DRTDIQCLIPCAIDQ----DPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQ-TKMSAS 353 R L DQ R+ R ++G A +H+ P + A TK S Sbjct: 183 HRRHGCTLQIGGADQWGNIIAGVRLVRQ---KLG----ATVHALTVPLVTAADGTKFGKS 235 Query: 354 DPNSSIFLT 362 S++L Sbjct: 236 TGGGSLWLD 244 >4OUD-B nrPDB Length = 394 Score = 71.3 bits (173), Expect = 8e-13, Method: Composition-based stats. Identities = 51/305 (16%), Positives = 99/305 (32%), Gaps = 34/305 (11%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D + + P LY G P+++++H GHL+P + K Q + P+ + Sbjct: 14 RGLVAQVTDEEALAERLAQG-PIALYCGFDPTADSLHAGHLVPLLCLKRFQQAGHKPVAL 72 Query: 194 ------QMTD-----DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 + D E+ L + T+ + + + N ++ D+ G Sbjct: 73 VGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFG 132 Query: 243 MSSGFYKNVVKIQKHVTFNQ------VKGIFGFTD-SDCIGKISFPAIQAAPSFSNSFPQ 295 + + I KH + NQ VK D + S+ +Q + Sbjct: 133 NMNVL-TFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQ-------GYDF 184 Query: 296 IFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDP 355 ++ L DQ D+ R+ + L G + + Sbjct: 185 ACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKAGKT---E 241 Query: 356 NSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQ 415 +++L D K K + A + + +FG ++ ED + + Sbjct: 242 GGAVWL-DPKKTSPYKFYQFAINAADADVYRWLKFGTFMSIE---EINALEEEDKNSGKA 297 Query: 416 IRKDY 420 R Y Sbjct: 298 PRAQY 302 >1H3F-A nrPDB Length = 432 Score = 70.5 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 44/247 (17%), Positives = 90/247 (36%), Gaps = 32/247 (12%) Query: 144 NQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLW 203 ++L + +P + G P+ +H+GH + + Q++ + +V+ + D + Sbjct: 26 EELLAKLKEGRPLTVKLGADPTRPDLHLGHAVVLRKMRQFQELGH-KVVLIIGDFTGMIG 84 Query: 204 KDLTLDQAY-----SYAVENAKDIIA-----CGFDINKTFIFSDLDYMGMSSGFYKNVVK 253 + ENAK +A + + + + +++ + +K VV+ Sbjct: 85 DPSGRSKTRPPLTLEETRENAKTYVAQAGKILRQEPHLFELRYNSEWLEGLT--FKEVVR 142 Query: 254 IQKHVTFNQVKGIFGFTDSDCIG------KISFPAIQAAPSFSNSFPQIFRDRTDIQCLI 307 + +T Q+ F G ++ +P QA S + R D++ Sbjct: 143 LTSLMTVAQMLEREDFKKRYEAGIPISLHELLYPFAQAYDSVA--------IRADVEM-- 192 Query: 308 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQ 367 DQ + R+V G L G + KMS S N I LT+ + Sbjct: 193 -GGTDQRFNLLVGREVQRAYGQSPQVCFLMPLLVGLDG-REKMSKSLDN-YIGLTEPPEA 249 Query: 368 IKTKVNK 374 + K+ + Sbjct: 250 MFKKLMR 256 >6HB6-A nrPDB Length = 424 Score = 69.0 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 77/232 (33%), Gaps = 27/232 (11%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D + + P LY G P+++++H+GHL+P + K Q + P+ + Sbjct: 13 RGLVAQVTDEEALAERLAQG-PIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVAL 71 Query: 194 ------QMTD-----DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 + D E+ L + T+ + + + N ++ D+ G Sbjct: 72 VGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFG 131 Query: 243 MSSGFYKNVVKIQKHVTFNQ------VKGIFGFTD-SDCIGKISFPAIQAAPSFSNSFPQ 295 + + I KH + NQ VK D + S+ +Q + Sbjct: 132 NMNVL-TFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQ-------GYDF 183 Query: 296 IFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQ 347 ++ L DQ D+ R+ + L G + Sbjct: 184 ACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTK 235 >1X8X-A nrPDB Length = 322 Score = 69.0 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 77/232 (33%), Gaps = 27/232 (11%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG+ D + + P LY G P+++++H+GHL+P + K Q + P+ + Sbjct: 13 RGLVAQVTDEEALAERLAQG-PIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVAL 71 Query: 194 ------QMTD-----DEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMG 242 + D E+ L + T+ + + + N ++ D+ G Sbjct: 72 VGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFG 131 Query: 243 MSSGFYKNVVKIQKHVTFNQ------VKGIFGFTD-SDCIGKISFPAIQAAPSFSNSFPQ 295 + + I KH + NQ VK D + S+ +Q + Sbjct: 132 NMNVL-TFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQ-------GYDF 183 Query: 296 IFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQ 347 ++ L DQ D+ R+ + L G + Sbjct: 184 ACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTK 235 >6BYQ-A nrPDB Length = 410 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 56/312 (17%), Positives = 95/312 (30%), Gaps = 61/312 (19%) Query: 148 DAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQD-----VFNVPLVIQMTDD---- 198 YE + F + G P++ +H+GH + LQ F + M D Sbjct: 39 KYYETNERFIVKAGFDPTAPDLHLGHTVLIQKLALLQQYGARVKFLIGDFTAMIGDPTGK 98 Query: 199 ---EKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGM--SSGFYKNVVK 253 K L ++ L+ A +Y + K D T + + ++ + G + K Sbjct: 99 NETRKPLNREQVLENAKTYEEQIYKI-----LDQKHTEVCFNSTWLDALGAKGMIELCAK 153 Query: 254 IQKHVTFNQVKGIFGFTDSDCIG--KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAI 311 + ++ I + +P +Q S + DI+ Sbjct: 154 FSVARMLERDDFAKRHKENRPISIVEFLYPLLQGYDSVA--------MGADIE---LGGN 202 Query: 312 DQDPYFRMTRDVAPRIGYPKPALLHS-TFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370 DQ + R + G K + + L G Q KMS S N Sbjct: 203 DQKFNLLVGRFLQRAYGLNKEQSIITMPLLEGLDGVQ-KMSKSLGNYV------------ 249 Query: 371 KVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSG----AML 426 T E + FG V M+ + L LE+I D G + Sbjct: 250 ----------GITEEPNAMFGKIMSVSDDLMWRYYTLLSAKTLEEIE-DLKHGILNQTLH 298 Query: 427 TGELKKALIEVL 438 +K+ L + Sbjct: 299 PKAVKEDLAGEI 310 >6N0W-A nrPDB Length = 480 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 45/244 (18%), Positives = 88/244 (36%), Gaps = 32/244 (13%) Query: 134 RGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVI 193 RG++ DM + NK+ Y G P+++++H+G LIP Q + P+ + Sbjct: 19 RGLWA---DMTPGTEDQLNKEMTTAYIGFDPTADSLHIGSLIPIKILAHFQRHGHKPIAL 75 Query: 194 Q-----MTDDE--KYLWKDLTLDQAYSYAVENAKDIIACGFD-----INKTFIFSDLDYM 241 M D K ++L ++ Y V+ K+ ++ D N+ + ++ D+M Sbjct: 76 VGGATGMIGDPSGKSAERNLLDEETLLYYVDCLKNQLSRFLDFEGDGPNRAELVNNYDWM 135 Query: 242 GMSSGFYKNVVKIQKHVTFNQVKG-------IFGFTDSDCIGK--ISFPAIQAAPSFSNS 292 + F I KH+T N + G +D + ++ +Q Sbjct: 136 KNVT-FLDFAKNIGKHITVNYMMAKDSVKKRFSGEDGADGMSFTEFTYQLLQ-------G 187 Query: 293 FPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSA 352 + + + L DQ ++ R + L + G++ S Sbjct: 188 YDYLHLYKEKGVKLQMGGSDQWGNITTGTELIRRKAQGEAFALTTKLITKADGSKFGKSE 247 Query: 353 SDPN 356 S N Sbjct: 248 SGEN 251 >5IHX-A nrPDB Length = 395 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 47/307 (15%), Positives = 99/307 (32%), Gaps = 66/307 (21%) Query: 112 IDKELINRIER------------ATGQRPH---HFLRRGIFFSHRDMNQVLDAYENKKPF 156 I + + RIE G+R H RG+ +L +K Sbjct: 7 ITQAYLQRIEEGKKEWAQFAQEIKEGKRKSFVEHLEERGLIHDVVGDRDLLHRVFTEKRV 66 Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAV 216 +Y G P++ +MHVGH++PF+ W V+ +P+ + + + Sbjct: 67 GIYAGVDPTAPSMHVGHMLPFMVLAW-GYVWGLPVTFLLGGATSRVGDPTGRLKGREQVH 125 Query: 217 ENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNV------------------------- 251 + + + + + ++ G G+ + + Sbjct: 126 SSVRKANMASMHMQLKKLGASIERYGEKHGYKRQMIWRRTLTNNNVWWNKTPLLEVLRDL 185 Query: 252 ---VKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSF-------------SNSFPQ 295 ++I + + VK D + ++P +QA + S+ + Sbjct: 186 GAYIRIGPMLGRDTVKNRMERGDGMSFAEFTYPLMQAWDWWMLFKNGCQVQVGGSDQYGN 245 Query: 296 IFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDP 355 I ++ + + Q+ ++ D+ IG+ P L S + K S Sbjct: 246 ILFGVGAVKTISKNTVLQEDNNPLSDDLDKPIGFTTPLLTTS--------SGEKFGKSAG 297 Query: 356 NSSIFLT 362 N +I+L Sbjct: 298 N-AIWLD 303 >5IJX-A nrPDB Length = 384 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 45/351 (12%), Positives = 99/351 (28%), Gaps = 63/351 (17%) Query: 112 IDKELINRIERA------------TGQR---PHHFLRRGIFFSHRDMNQVLDAYENKKPF 156 I ++ + R A G++ RG+ S LD +K Sbjct: 7 ITQQHLRRTAEAEEQWKLQAKEIEAGRKQSFLSFLEERGLVNSVVGQRDALDKLITRKRV 66 Query: 157 YLYTGRGPSSEAMHVGHLIPFIFTKW-----LQDVFNVPLVIQMTDD-------EKYLWK 204 Y G P++ ++H+GH++PF+ W L+ VF + D + Sbjct: 67 GFYAGVDPTAPSLHIGHMLPFMILGWAYVHGLKAVFLIGGSTAKIGDPTGRLEGRPLMDG 126 Query: 205 DLTLDQAYSYAVENAKDIIAC-------GFD--------INKTFIFSDLDYMGMSSGFYK 249 + ++ + + GF+ + + + + Sbjct: 127 ATRRANIANIHLQLKRLGFSFEKYGRKHGFEWEWAWRRALENNNTWWNKQSLKEVMEVLG 186 Query: 250 NVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPS--FSNSFPQIFRDRTDIQCLI 307 +++ + + VK + I + +P +Q Q+ +D I Sbjct: 187 TSLRLGPMLGRDYVKSRLASGEGMSIAEFCYPIMQGWDFWYLFQRKVQVQVGGSDQYGNI 246 Query: 308 PCAIDQDPYFRMTR---DVAPRIGY-PKPALLHSTFFPALQGAQTKMSASDPNSSIFLTD 363 +D + AP+ P A + P L A + ++++L Sbjct: 247 LFGMDAIKGILKANPESEWAPKKDEDPDLANPYGITTPLLTTASGEKIGKSAGNAVWLDK 306 Query: 364 T---------------AKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVS 399 ++ + F E + + V+ Sbjct: 307 DMTSCYDLYQYFVRVADSDVERYLKMFTFVPTPAIKELMEEHAKDPSKRVA 357 >2RKJ-A nrPDB Length = 392 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 35/266 (13%), Positives = 81/266 (30%), Gaps = 34/266 (12%) Query: 131 FLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQ-DVFNV 189 F RG + + + Y G P++ ++HVGHL+P + W+ + + Sbjct: 40 FEERGYVKDTAGTKEHIAELMRTRRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKA 99 Query: 190 PLVI--------------QMTDDEKYLWKDLTLDQAYSYAVENAKD----IIACGFDINK 231 +I + D + + + + + ++ + A G++ + Sbjct: 100 FTLIGGSTAKIGDPTGRLKSRDHLSSSDATMNMTKIHYQLKKLWENVDTQMRARGYEADW 159 Query: 232 TFI--------FSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAI 283 + + M + ++I ++ + VK D + ++P + Sbjct: 160 ARKRGIVNNNHWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMTQGDGVSFAEFTYPIM 219 Query: 284 QAAP---SFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHST-- 338 Q F Q+ +D I ++ R + Y P Sbjct: 220 QGWDWFELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKYVTPKTALDECV 279 Query: 339 --FFPALQGAQTKMSASDPNSSIFLT 362 P L + ++I+L Sbjct: 280 GFTVPLLTDSSGAKFGKSAGNAIWLD 305 >2PID-A nrPDB Length = 356 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 33/264 (12%), Positives = 85/264 (32%), Gaps = 50/264 (18%) Query: 134 RGIF---FSHR----DMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDV 186 RG+F F ++ ++ D P +Y G P+++++HVGHL+ + LQ Sbjct: 18 RGLFKDFFPETGTKIELPELFDRGTASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRA 77 Query: 187 FNVPLVIQMTDDEKYLW---------KDLTLDQAYSYAVENAKDIIACGFDINKTFI--- 234 + ++ + L + L ++ + A + A + + F Sbjct: 78 GH-NVIALVGGATARLGDPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGR 136 Query: 235 ----------------FSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKI 278 +D++ G ++ + + ++K + + + Sbjct: 137 SWGSFTVLDNSAWYQKQHLVDFLAAVGGHFRMGTLLSRQSVQLRLKS----PEGMSLAEF 192 Query: 279 SFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHST 338 + +QA + + + + DQ + ++ + Sbjct: 193 FYQVLQA-------YDFYYLFQRYGCRVQLGGSDQLGNIMSGYEFINKLTGEDVFGITVP 245 Query: 339 FFPALQGAQTKMSASDPNSSIFLT 362 + GA+ SA ++++L Sbjct: 246 LITSTTGAKLGKSA---GNAVWLN 266 >2DJV-A nrPDB Length = 79 Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 31/57 (54%) Query: 4 SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 ++P + L + + QG +VR LKA A K+E+ + V L+ LK A G+ +A Sbjct: 10 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 66 >2VA8-A nrPDB Length = 715 Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 56/152 (36%), Gaps = 7/152 (4%) Query: 321 RDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQI--KTKVNKHAFS 378 + +A +G +P + P ++G + IF +T K++ + + Sbjct: 189 KQIAKWLG-AEPVATNWRPVPLIEGVIYPERKKKEYNVIFKDNTTKKVHGDDAIIAYTLD 247 Query: 379 G----GRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKAL 434 G+ + + + Y+ F D++ L +I K + K+ L Sbjct: 248 SLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDDIEEGGSDEKELL 307 Query: 435 IEVLQPLIAEHQARRKEVTDEIVKEFMTPRKL 466 ++ +A H A + ++++E RK+ Sbjct: 308 KSLISKGVAYHHAGLSKALRDLIEEGFRQRKI 339 >4E4R-A nrPDB Length = 331 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 36/96 (37%), Gaps = 10/96 (10%) Query: 191 LVIQMTDDEKYLWKDLTLDQ------AYSYAVENAKDIIACGFDINKTFIFSDLDYMGMS 244 + + DE+Y++ D ++ AVE+AK ++ G D + S Sbjct: 155 IFFMIKGDEQYIFGDCAINPELDSQGLAEIAVESAKSALSFGMDPKVAMLSFSTKGSAKS 214 Query: 245 SGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISF 280 V K+Q+ V Q K ++ G+ F Sbjct: 215 DD----VTKVQEAVKLAQQKAEEEKLEAIIDGEFQF 246 >4Z5Q-A nrPDB Length = 423 Score = 31.6 bits (70), Expect = 0.80, Method: Composition-based stats. Identities = 33/201 (16%), Positives = 63/201 (31%), Gaps = 31/201 (15%) Query: 289 FSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQT 348 S S+ ++F D I+ +P P + +TR R A Q + Sbjct: 48 LSQSYAKLFEDGDPIRVQLPFGE---PAWLVTRYDDARFVLTDRRFSRH---LATQRDEP 101 Query: 349 KMSASDPNSSIFLTDTAKQIK-TKVNKHAFSGGRDTIEE------------HRQFGGNCD 395 +M+ SI D + + AF+ R + + GG Sbjct: 102 RMTPRAVPESILTMDPPDHTRLRTLVSKAFTPRRIESKRAWIGELAAGLVADMKAGGAPA 161 Query: 396 -----------VDVSFMYLTFFLEDDDKLEQ-IRKDYTSGAMLTGELKKALIEVLQPLIA 443 V V L +D +L ++G + E ++ +++ + Sbjct: 162 ELVGSYALAIPVTVICELLGVPEDDRTRLRGWCDAALSTGELTDEECVQSFMDLQKYFED 221 Query: 444 EHQARRKEVTDEIVKEFMTPR 464 + RR E D++ + R Sbjct: 222 LVKERRAEPRDDLTSALIEAR 242 >6G9C-A nrPDB Length = 495 Score = 31.2 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 18/40 (45%), Gaps = 3/40 (7%) Query: 50 YKAAAGEDYKADCPPG---NPAPTSNHGPDATEAEEDFVD 86 Y+ A G YK CP G NP ++ P + +E + Sbjct: 449 YQCAGGTAYKMKCPTGLMFNPKTSTCDYPSNVDCQEKTIT 488 >2Y7H-B nrPDB Length = 529 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 106 RFGSS-KIDKELINRIERATGQRPHHFLRR--GIFFSHRDMNQVLDAYENK 153 FG E + ER G+ PH R G + + + +V D+ ENK Sbjct: 386 SFGKRTPFTDEHLQPFERVYGEDPHGLSPRTEGEWSFNAEETEVADSEENK 436 >3LAD-A nrPDB Length = 476 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 17/40 (42%) Query: 78 TEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELI 117 TE + V V K +DKLIV G + +L+ Sbjct: 247 TEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLL 286 >2REO-A nrPDB Length = 305 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%), Gaps = 4/40 (10%) Query: 393 NCDVDVSFMYLTF----FLEDDDKLEQIRKDYTSGAMLTG 428 N + Y F+ D LE+ + + SG ++ G Sbjct: 141 NPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGG 180 >5U8W-A nrPDB Length = 481 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 19/41 (46%) Query: 77 ATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELI 117 A+E ++ V + + +DKLIV G + +L+ Sbjct: 250 ASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLL 290 >4ZTY-A nrPDB Length = 769 Score = 28.9 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Query: 5 EPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPP 64 +P +LL+ + EL++ LKA A +ID V ++ L+ KAA Y+A Sbjct: 179 DPITLLDKL--VPVYVELLKQLKAAGAESVQIDEPV-LVFDLRPEVKAAFKPAYEAIAAA 235 Query: 65 GNPAP 69 G+ P Sbjct: 236 GDAVP 240 >5YZG-y nrPDB Length = 307 Score = 28.2 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 19/48 (39%) Query: 376 AFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSG 423 A +GG + R+ + F Y + EDD + + ++Y Sbjct: 155 AEAGGSQALPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKK 202 >4ITN-A nrPDB Length = 315 Score = 28.2 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 24/66 (36%) Query: 102 KLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTG 161 K I R + + + + E TG+ R + D +V ++ ++G Sbjct: 175 KEIRRADALVLTYQEVEPFEFFTGKPTFKMFREFCCLLNSDFEEVPFDILKEREVIAFSG 234 Query: 162 RGPSSE 167 G + + Sbjct: 235 LGDNGQ 240 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.129 0.333 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,749,044 Number of Sequences: 36641 Number of extensions: 635837 Number of successful extensions: 2275 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 91 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 2000 Number of HSP's gapped (non-prelim): 125 length of query: 471 length of database: 10,336,785 effective HSP length: 101 effective length of query: 370 effective length of database: 6,636,044 effective search space: 2455336280 effective search space used: 2455336280 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)