BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23280 (308 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3FE4-A nrPDB 572 e-164 5DVX-A nrPDB 205 2e-53 4LU3-A nrPDB 188 3e-48 5LL9-A nrPDB 185 2e-47 1RJ5-A nrPDB 184 4e-47 6G4T-A nrPDB 159 2e-39 4QK3-A nrPDB 155 2e-38 1Z93-A nrPDB 153 8e-38 1FLJ-A nrPDB 149 1e-36 4CNR-A nrPDB 147 8e-36 3D0N-A nrPDB 146 1e-35 6FAF-A nrPDB 135 2e-32 2W2J-A nrPDB 130 5e-31 5JN8-A nrPDB 130 9e-31 3ZNC-A nrPDB 124 4e-29 1URT-A nrPDB 120 1e-27 5HPJ-A nrPDB 108 4e-24 4X5S-A nrPDB 105 2e-23 4COQ-A nrPDB 99 2e-21 4G7A-A nrPDB 98 5e-21 6EKI-A nrPDB 94 5e-20 4XZ5-A nrPDB 86 1e-17 4XIW-A nrPDB 86 2e-17 1KOQ-A nrPDB 85 4e-17 4TWL-A nrPDB 73 2e-13 4ETQ-X nrPDB 72 3e-13 6B9J-X nrPDB 72 3e-13 1Y7W-A nrPDB 67 9e-12 3B1B-A nrPDB 65 2e-11 3Q31-A nrPDB 59 3e-09 5TT3-A nrPDB 55 3e-08 1LW3-A nrPDB 30 1.4 5M3L-D nrPDB 28 4.0 6Q63-A nrPDB 28 4.6 4V93-B0 nrPDB 28 5.8 4M7V-A nrPDB 28 6.7 >3FE4-A nrPDB Length = 278 Score = 572 bits (1473), Expect = e-164, Method: Compositional matrix adjust. Identities = 270/271 (99%), Positives = 271/271 (100%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 79 +SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP Sbjct: 1 MSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 60 Query: 80 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI Sbjct: 61 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 120 Query: 140 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL Sbjct: 121 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 180 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 259 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI Sbjct: 181 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 240 Query: 260 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ 290 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ Sbjct: 241 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ 271 >5DVX-A nrPDB Length = 260 Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 104/258 (40%), Positives = 150/258 (58%), Gaps = 8/258 (3%) Query: 23 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA-GEFPMV 81 W Y + WP+ PAC G+ QSP++++ ++P+L+ L ++G++ E + Sbjct: 2 WRYG----GDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLR 57 Query: 82 NNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVH 141 NNGH+VQ++LP + M + G Y A Q+H HWG A GSEHTV+G R EIH+VH Sbjct: 58 NNGHSVQLTLPPGLEMKLGPGREYRALQLHLHWGAAGR--PGSEHTVEGHRFPAEIHVVH 115 Query: 142 YNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDV 201 ++KY D A P GLAVLAAF+E + EN+ Y +S L I G T + GLD+ Sbjct: 116 LSTKYARVDEALGRPGGLAVLAAFLE-EGPEENSAYEQLLSRLEEIAEEGSETQVPGLDI 174 Query: 202 QDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHN 261 +LP + Y+ Y GSLTTPPC + V W V V LS Q+ L ++L + + Sbjct: 175 SALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGDSRLQL 234 Query: 262 DYRRTQPLNHRVVESNFP 279 ++R TQPLN RV+E++FP Sbjct: 235 NFRATQPLNGRVIEASFP 252 >4LU3-A nrPDB Length = 279 Score = 188 bits (477), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 106/262 (40%), Positives = 155/262 (59%), Gaps = 11/262 (4%) Query: 23 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV- 81 WTY EG + HWP YP CG QSPI++Q V ++P L L GY+ Q G P+ Sbjct: 7 WTY-EGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYD-QPGTEPLDL 64 Query: 82 -NNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140 NNGHTVQ+SLPST+ + Y+A Q+H HWG S GSEH ++ E+HIV Sbjct: 65 HNNGHTVQLSLPSTLYLGGLP-RKYVAAQLHLHWGQKGSP-GGSEHQINSEATFAELHIV 122 Query: 141 HYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199 HY+S Y S A + P GLAVL +EV +N Y + +SHL +++ Q+T++ Sbjct: 123 HYDSDSYDSLSEAAERPQGLAVLGILIEVGET-KNIAYEHILSHLHEVRHKDQKTSVPPF 181 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL---DHRN 256 +++++LP+ L Y+ Y+GSLTTPPC ++V W V ++S Q+ KL+ +L + + Sbjct: 182 NLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPS 241 Query: 257 KTIHNDYRRTQPLNHRVVESNF 278 K + +YR QPLN R+V ++F Sbjct: 242 KLLVQNYRALQPLNQRMVFASF 263 >5LL9-A nrPDB Length = 263 Score = 185 bits (469), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 104/266 (39%), Positives = 152/266 (57%), Gaps = 12/266 (4%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG-EF 78 +S WTY G E W + YP+CGG QSPI+L ++Y+ SL L GY A +F Sbjct: 1 MSKWTYF-GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQF 59 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 + NNGH+V+++LPS M + + Y A Q+H HWG + + GSEHTV G E+H Sbjct: 60 LLTNNGHSVKLNLPSDMHIQGLQ-SRYSATQLHLHWGNPN-DPHGSEHTVSGQHFAAELH 117 Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 IVHYNS Y A + +GLAVLA +E+ ++ N Y SHL ++KY GQ + Sbjct: 118 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF--NPSYDKIFSHLQHVKYKGQEAFVP 175 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL----- 252 G +++++LP YY Y GSLTTPPC V W V + V++S+ Q+ LE +L Sbjct: 176 GFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMD 235 Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278 D + + N++R+ Q + R+V ++F Sbjct: 236 DPSPREMINNFRQVQKFDERLVYTSF 261 >1RJ5-A nrPDB Length = 261 Score = 184 bits (467), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 104/262 (39%), Positives = 152/262 (58%), Gaps = 11/262 (4%) Query: 23 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV- 81 WTY EG + HWP YP CGG QSPIN+Q V ++P L + GY+ Q G P+ Sbjct: 5 WTY-EGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYD-QLGTEPLDL 62 Query: 82 -NNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140 NNGHTVQ+SLP T+ + Y A Q+H HWG S + GSEH ++ E+H+V Sbjct: 63 HNNGHTVQLSLPPTLHLGGLP-RKYTAAQLHLHWGQRGS-LEGSEHHINSEATAAELHVV 120 Query: 141 HYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199 HY+S+ Y S A P GLAVL +EV EN Y + +S L I+Y Q+T++ Sbjct: 121 HYDSQSYSSLSEAAQKPQGLAVLGILIEVGET-ENPAYDHILSRLHEIRYKDQKTSVPPF 179 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL---DHRN 256 V+++ P+ L+ ++ Y+GSLTTPPC ++V W V ++S Q+ KL+ +L + + Sbjct: 180 SVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPS 239 Query: 257 KTIHNDYRRTQPLNHRVVESNF 278 + + +YR QPLN R + ++F Sbjct: 240 EPLVQNYRVPQPLNQRTIFASF 261 >6G4T-A nrPDB Length = 274 Score = 159 bits (401), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 97/264 (36%), Positives = 148/264 (56%), Gaps = 16/264 (6%) Query: 23 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82 W Y + +HW + YP G RQSPIN+ ++ Y+PSL+ L ++ YE + N Sbjct: 9 WGYGQDD-GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS-YEA-CMSLSITN 65 Query: 83 NGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 NGH+VQ+ + TV G Y +Q HFHWG GSEHTVDG E+H Sbjct: 66 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWG--KKHDVGSEHTVDGKSFPSELH 123 Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 +VH+N+K Y ++ A APDGLAV+ F+E + E+ + L +++ G + + Sbjct: 124 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFS 181 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-DHRN 256 + + +LP + +HY+TY GSLTTPP +E+V W VL + + +S Q+ K + L + Sbjct: 182 CFNPKSLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDD 240 Query: 257 KTIH--NDYRRTQPLNHRVVESNF 278 + IH N++R QPL RVV+++F Sbjct: 241 ERIHMVNNFRPPQPLKGRVVKASF 264 >4QK3-A nrPDB Length = 249 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 90/249 (36%), Positives = 136/249 (54%), Gaps = 19/249 (7%) Query: 34 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93 HW + +P G+RQSP+++ +Y+PSLK L+++ Y+ QA ++NNGH + Sbjct: 15 HWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YD-QATSLRILNNGHAFNVEFDD 72 Query: 94 TMRMTVADGT----VYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 149 + V G Y Q HFHWG S + GSEHTVD ++ E+H+VH+N+KY + Sbjct: 73 SQDKAVLKGGPLDGTYRLIQFHFHWG--SLDGQGSEHTVDKKKYAAELHLVHWNTKYGDF 130 Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209 A PDGLAVL F++V + + L +IK G+ T D + +LP +L Sbjct: 131 GKAVQQPDGLAVLGIFLKVGS--AKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESL 188 Query: 210 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPL 269 Y+TY GSLTTPP E V W VL + + +S QV K ++D ++R QPL Sbjct: 189 D-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLMVD--------NWRPAQPL 239 Query: 270 NHRVVESNF 278 +R ++++F Sbjct: 240 KNRQIKASF 248 >1Z93-A nrPDB Length = 266 Score = 153 bits (387), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 86/252 (34%), Positives = 144/252 (57%), Gaps = 14/252 (5%) Query: 34 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93 HW + +P G+ QSPI L +R++PSL+ +++ Y+ + + ++NNG T ++ Sbjct: 15 HWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVS-YDGGSAKT-ILNNGKTCRVVFDD 72 Query: 94 TMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 149 T ++ G Y +Q H HWG SS+ GSEHTVDG+++ E+H+VH+N KY ++ Sbjct: 73 TYDRSMLRGGPLPGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAAELHLVHWNPKYNTF 130 Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209 A DG+AV+ F+++ + EN + F+ L IK G+ T D + P + Sbjct: 131 KEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFTKFDPSSLFPAS- 187 Query: 210 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK---TIHNDYRRT 266 + Y+TY GS TTPPC E + W +L + + +S Q+ KL + L N+ + +++R Sbjct: 188 RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPP 247 Query: 267 QPLNHRVVESNF 278 QP+N+RVV ++F Sbjct: 248 QPINNRVVRASF 259 >1FLJ-A nrPDB Length = 260 Score = 149 bits (377), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 87/266 (32%), Positives = 141/266 (53%), Gaps = 15/266 (5%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 79 +W Y+ E HW + YP G QSPI L +R++PSL+ +++ Y+ + + Sbjct: 2 AKEWGYASHNGPE-HWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVS-YDPGSAKT- 58 Query: 80 MVNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135 ++NNG T ++ T ++ G Y +Q H HWG SS+ GSEHTVDG+++ Sbjct: 59 ILNNGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAA 116 Query: 136 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 E+H+VH+N KY ++ A PDG+AV+ F+++ E + + L IK G+ Sbjct: 117 ELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGR--EKGEFQILLDALDKIKTKGKEAP 174 Query: 196 LTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 D + P + Y+TYHGS TTPPC E + W +L + + +S Q+ KL + Sbjct: 175 FNHFDPSCLFP-ACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAE 233 Query: 256 NK---TIHNDYRRTQPLNHRVVESNF 278 N+ + ++R QP+ RVV ++F Sbjct: 234 NEPPVPLVGNWRPPQPIKGRVVRASF 259 >4CNR-A nrPDB Length = 262 Score = 147 bits (370), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 89/253 (35%), Positives = 135/253 (53%), Gaps = 15/253 (5%) Query: 34 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93 HW + +P G+RQSP+++ V +P+LK L + E + MVN+GH+ + Sbjct: 17 HWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRR--MVNDGHSFNVEYDD 74 Query: 94 TM-RMTVADGTV---YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 149 + + + DG + Y Q HFHWG SS+ GSEHTVD ++ E+H+VH+N+KY + Sbjct: 75 SQDKAVLKDGPLTGTYRLVQFHFHWG--SSDDQGSEHTVDRKKYAAELHLVHWNTKYGDF 132 Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209 A PDGLAV+ F++V + N + L +IK G+ T D +LP N+ Sbjct: 133 GTAAQEPDGLAVVGVFLKVGD--ANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLP-NV 189 Query: 210 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKT---IHNDYRRT 266 Y+TY GSLTTPP E+V W VL + + +S Q+ K + + + ++R Sbjct: 190 LDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELMLANWRPA 249 Query: 267 QPLNHRVVESNFP 279 QPL +R V FP Sbjct: 250 QPLKNRQVRG-FP 261 >3D0N-A nrPDB Length = 264 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 87/253 (34%), Positives = 137/253 (54%), Gaps = 15/253 (5%) Query: 34 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93 HW + +P G +QSPI ++ +V+Y+ SL+ L++ Y+ + + + N+GH+ + Sbjct: 18 HWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIK-YDPSSAKI-ISNSGHSFNVDFDD 75 Query: 94 TMRMTVADGT----VYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNS-KYKS 148 T +V G Y +Q+H HWG A GSEH VDG+ + E+H+VH+NS KY S Sbjct: 76 TENKSVLRGGPLTGSYRLRQVHLHWGSADDH--GSEHIVDGVSYAAELHVVHWNSDKYPS 133 Query: 149 YDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRN 208 + A PDGLAVL F+++ N+ L +IK G++T T D+ +LP + Sbjct: 134 FVEAAHEPDGLAVLGVFLQIGE--PNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPS 191 Query: 209 LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKT---IHNDYRR 265 Y+TY GSLT PP E+V W VL + +S Q+ K + L + + +++R Sbjct: 192 WD-YWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRP 250 Query: 266 TQPLNHRVVESNF 278 QPL R V ++F Sbjct: 251 PQPLKGRKVRASF 263 >6FAF-A nrPDB Length = 261 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 137/266 (51%), Gaps = 18/266 (6%) Query: 22 DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81 DW Y + E W + YP G QSP++++ ++ +++ SLK ++++ A E ++ Sbjct: 5 DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61 Query: 82 NNGHTVQISLPSTMRMTVADGTVYIAQ----QMHFHWGGASSEISGSEHTVDGIRHVIEI 137 N GH+ ++ +V G + Q HFHWG S+ GSEHTVDG+++ E+ Sbjct: 62 NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWG--STNEHGSEHTVDGVKYSAEL 119 Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 H+ H+NS KY S A DGLAV+ ++V N + L IK G+R Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252 T D +LP +L ++TY GSLT PP E+V W + + + +S Q+ + L N Sbjct: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236 Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278 D+ HN+ R TQPL R V ++F Sbjct: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261 >2W2J-A nrPDB Length = 291 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 135/259 (52%), Gaps = 17/259 (6%) Query: 33 AHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLP 92 W +P G+ QSPINL + RY+PSL + ++ + + N+GHT+Q+ L Sbjct: 36 VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILK 95 Query: 93 STMRMT---VADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKS 148 S ++ + G + ++ FHWG + GSEHTV+ +E+H++H+NS + S Sbjct: 96 SKSVLSGGPLPQGHEFELYEVRFHWGRENQR--GSEHTVNFKAFPMELHLIHWNSTLFGS 153 Query: 149 YDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRN 208 D A P G+A++A FV++ E+ L +I+Y G+ T+ + +LP Sbjct: 154 IDEAVGKPHGIAIIALFVQIGK--EHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDP 211 Query: 209 -LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLEN--------SLLDHRNKTI 259 L+ Y+ Y GSLT PPC+E V W + + +S+ Q+ + L++ + + Sbjct: 212 LLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGIL 271 Query: 260 HNDYRRTQPLNHRVVESNF 278 +++R TQPL+ RV+ + F Sbjct: 272 GDNFRPTQPLSDRVIRAAF 290 >5JN8-A nrPDB Length = 266 Score = 130 bits (326), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 89/268 (33%), Positives = 136/268 (50%), Gaps = 21/268 (7%) Query: 21 SDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA 75 S W Y E + +++P P C RQSPIN+ TK + + L +GY+ + Sbjct: 3 SHWCY-EVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 76 GEFPMVNNGHTVQISLPSTMRMTVADGTV---YIAQQMHFHWGGASSEISGSEHTVDGIR 132 + + NNGH+V + L + + +++ G + Y A+Q+H HW GSEH++DG Sbjct: 62 T-WTVQNNGHSVMMLLEN--KASISGGGLPAPYQAKQLHLHWSDLP--YKGSEHSLDGEH 116 Query: 133 HVIEIHIVHYNSKYKSYDI--AQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 190 +E+HIVH K S ++ AQD D +AVLA VE N + + L+NI P Sbjct: 117 FAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQV-NEGFQPLVEALSNIPKP 175 Query: 191 GQRTTLTGLDVQDMLPR--NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLE 248 TT+ + D+LP+ L+HY+ Y GSLTTP C E V W V + ++L R Q+ Sbjct: 176 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 235 Query: 249 NSLLDHRNKTI--HNDYRRTQPLNHRVV 274 L + +T+ ++ R Q L R V Sbjct: 236 QKLYYDKEQTVSMKDNVRPLQQLGQRTV 263 >3ZNC-A nrPDB Length = 258 Score = 124 bits (312), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 84/261 (32%), Positives = 131/261 (50%), Gaps = 17/261 (6%) Query: 23 WTY---SEGALDEAHWPQHYP-ACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEF 78 W Y +E P+ +P AC +QSPIN+ + + NP L + GY+ Q ++ Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD-QKQQW 59 Query: 79 PMVNNGHTVQISLPSTMRMTVAD-GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137 P+ NN HTV+++L + D Y A Q+H HW + +GSEH++DG +E+ Sbjct: 60 PIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGND--NGSEHSIDGRHFAMEM 117 Query: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 HIVH K +D+ D AVLA +EV + N + + L +I P +T+ Sbjct: 118 HIVHK----KLTSSKEDSKDKFAVLAFMIEVGDK-VNKGFQPLVEALPSISKPHSTSTVR 172 Query: 198 GLDVQDMLPRNLQHY--YTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL--D 253 +QDMLP + + Y + Y+GSLTTP C E V W V +K+ + Q + +L + Sbjct: 173 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 232 Query: 254 HRNKTIHNDYRRTQPLNHRVV 274 + + ++ R QPL R V Sbjct: 233 DQKLNMKDNVRPLQPLGKRQV 253 >1URT-A nrPDB Length = 248 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/243 (32%), Positives = 126/243 (51%), Gaps = 15/243 (6%) Query: 44 GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGT 103 G RQSPIN+Q Y+P L L ++ Y+ + + + N GH Q+ + + G Sbjct: 4 GTRQSPINIQWKDSVYDPQLAPLRVS-YDAASCRY-LWNTGHAFQVEFDDSCEDSGISGG 61 Query: 104 V----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNS-KYKSYDIAQDAPDG 158 Y +Q HFHWG +++ GSEH VDG + E+H+VH+NS KY++Y A +G Sbjct: 62 PLGNHYRLKQFHFHWG--ATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENG 119 Query: 159 LAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGS 218 LAV+ F+++ + + + L +++ + + D ++P + Y+TY GS Sbjct: 120 LAVIGVFLKLGAH--HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMP-ACRDYWTYPGS 176 Query: 219 LTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK---TIHNDYRRTQPLNHRVVE 275 LTTPP E+V W V V++S +Q+ L R + + N+YR QPL R + Sbjct: 177 LTTPPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLR 236 Query: 276 SNF 278 S+F Sbjct: 237 SSF 239 >5HPJ-A nrPDB Length = 217 Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 125/255 (49%), Gaps = 42/255 (16%) Query: 22 DWTYSEGALDEAHWPQHYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPM 80 +W+Y+ G HW + C G Q+PI++ +T L L++ YE Q E + Sbjct: 1 EWSYT-GEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHL-DYEGQVTE--L 53 Query: 81 VNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140 VNNGHT+Q +L +TV DG + +Q HFH + SE+ + G ++ +E H V Sbjct: 54 VNNGHTIQANLTGKNTLTV-DGKTFELKQFHFH--------TPSENYLKGKQYPLEAHFV 104 Query: 141 HYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT-GL 199 H K + LAV+A + N + LA+I GQ L L Sbjct: 105 HATDKGE-----------LAVVAVMFDFGPRSNN----ELTTLLASIPSKGQTVELKEAL 149 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 259 + D+LPR+ + YY ++GSLTTPPC+E V WFV+ + S+ Q KL+ + Sbjct: 150 NPADLLPRD-REYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQ--------AVM 200 Query: 260 HNDYRRTQPLNHRVV 274 N+ R QPLN R++ Sbjct: 201 GNNARPLQPLNARLI 215 >4X5S-A nrPDB Length = 232 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/270 (31%), Positives = 135/270 (50%), Gaps = 44/270 (16%) Query: 14 GGQAQHVSDWTYSEGALDEAHWPQHYPA---CGGQRQSPINLQRTKVRYNPSLKGLNMTG 70 G V W+Y EG +W + P C + QSP+++ + + L+ L++ Sbjct: 1 GSHMAEVHHWSY-EGENGPENWAKLNPEYFWCNLKNQSPVDISDN-YKVHAKLEKLHINY 58 Query: 71 YETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDG 130 + E +VNNGHT+Q+++ ++ + G Y +Q HFH + SEHTV+G Sbjct: 59 NKAVNPE--IVNNGHTIQVNVLEDFKLNIK-GKEYHLKQFHFH--------APSEHTVNG 107 Query: 131 IRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFV-EVKNYPE-NTYYSNFISHLANIK 188 + +E+H+VH +D +AV+ F E K PE + + N + K Sbjct: 108 KYYPLEMHLVH-----------KDKDGNIAVIGVFFKEGKANPELDKVFKNAL------K 150 Query: 189 YPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLE 248 G + +++ +LP +++YYTY GSLTTPPCTE V W VL + S+ Q+ +L Sbjct: 151 EEGSKVFDGSININALLPP-VKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQI-ELF 208 Query: 249 NSLLDHRNKTIHNDYRRTQPLNHR-VVESN 277 S++ H N R TQP+N R ++ESN Sbjct: 209 KSIMKHNNN------RPTQPINSRYILESN 232 >4COQ-A nrPDB Length = 247 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 120/258 (46%), Gaps = 44/258 (17%) Query: 23 WTYSEGALDEAHW----PQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEF 78 W YS G++ HW P++ G+ QSPI++ L +++ Y ++ Sbjct: 26 WGYS-GSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAPVSV--YYVSDAKY 81 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 +VNNGHT+++ + V DG + +Q HFH + SEHTV+G + E H Sbjct: 82 -VVNNGHTIKVVM-GGRGYVVVDGKRFYLKQFHFH--------APSEHTVNGKHYPFEAH 131 Query: 139 IVHYNSKYKSYDIAQDAPDGLAVLAAFVEV-KNYPENTYYSNFISHLANIKYPGQRTTLT 197 VH D + VL F +V K PE + + PGQ+ LT Sbjct: 132 FVHL-----------DKNGNITVLGVFFKVGKENPELEKVWRVMP-----EEPGQKRHLT 175 Query: 198 G-LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 +D + +LP N + YY Y GSLTTPPC+E V W V + V++SR Q+ K + N Sbjct: 176 ARIDPEKLLPEN-RDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNN 234 Query: 257 KTIHNDYRRTQPLNHRVV 274 + + QPLN R V Sbjct: 235 RPV-------QPLNARKV 245 >4G7A-A nrPDB Length = 248 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 80/260 (30%), Positives = 123/260 (47%), Gaps = 39/260 (15%) Query: 22 DWTYSEGALDEAHWPQHYPA---CGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEF 78 +W+Y EG HW Q P C + QSPIN+ + K + +L LN+ Y A E Sbjct: 25 EWSY-EGEKGPEHWAQLKPEFFWCKLKNQSPINIDK-KYKVKANLPKLNL--YYKTAKES 80 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 +VNNGHT+QI++ + G Y +Q HFH + SEHT++ + +EIH Sbjct: 81 EVVNNGHTIQINIKEDNTLNYL-GEKYQLKQFHFH--------TPSEHTIEKKSYPLEIH 131 Query: 139 IVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG 198 VH DG +L V K N ++ G++ Sbjct: 132 FVH------------KTEDG-KILVVGVMAKLGKTNKELDKILN--VAPAEEGEKILDKN 176 Query: 199 LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKT 258 L++ +++P++ + Y TY GSLTTPPCTE V W VL + +S+ Q+ KL++ +++ N Sbjct: 177 LNLNNLIPKD-KRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNN-- 233 Query: 259 IHNDYRRTQPLNHRVVESNF 278 R Q +N R + F Sbjct: 234 -----RPVQEINSRWIIEGF 248 >6EKI-A nrPDB Length = 226 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 81/268 (30%), Positives = 118/268 (44%), Gaps = 61/268 (22%) Query: 20 VSDWTYSEGALDEAHW---PQHYPACG-GQRQSPINLQRT------KVRYNPSLKGLNMT 69 V W+Y G HW Y C G+ QSP+++ R K++ N S G ++T Sbjct: 3 VGHWSY-HGETGPQHWGDLKNEYIMCKIGKNQSPVDISRIVEAELEKIKINYSSGGSSIT 61 Query: 70 GYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVD 129 NNGHT+++S + V DG + +Q HFH + SEHT+ Sbjct: 62 ------------NNGHTIKVSYEPGSYIIV-DGIRFELKQFHFH--------APSEHTIK 100 Query: 130 GIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAA-FVEVKNYPENTYYSNFISHL-ANI 187 G + E H VH D LAV+ F E K P I + N+ Sbjct: 101 GKSYPFEAHFVH-----------ADKDGNLAVIGVIFKEGKKNP-------IIEKIWENL 142 Query: 188 KYPGQRTTLT-GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK 246 G+ L ++ D+LP+ + YY Y GSLTTPPC+E V W V+ + ++LS+ Q+ K Sbjct: 143 PEAGKTIKLAHKINAYDLLPKK-KKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEK 201 Query: 247 LENSLLDHRNKTIHNDYRRTQPLNHRVV 274 + N R QPLN R++ Sbjct: 202 FRKLMGGDTN-------RPVQPLNARMI 222 >4XZ5-A nrPDB Length = 233 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/238 (28%), Positives = 109/238 (45%), Gaps = 34/238 (14%) Query: 44 GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGT 103 G+ QSPINL+ SL G ++ ET ++NNGHT+Q+++P + + +G Sbjct: 28 GKNQSPINLKPQTAVGTTSLPGFDVYYRET---ALKLINNGHTLQVNIPLGSYIKI-NGH 83 Query: 104 VYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLA 163 Y Q HFH + SEH DG + +E+H+VH +D LAV+A Sbjct: 84 RYELLQYHFH--------TPSEHQRDGFNYPMEMHLVH-----------KDGDGNLAVIA 124 Query: 164 AFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPP 223 + EN + +S L + + P + + +Y Y GSLTTPP Sbjct: 125 ILFQEGE--ENETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPAD-KKFYKYSGSLTTPP 181 Query: 224 CTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQ 281 C+E V+W V ++ S TQ+ K+ L ++ R Q N R + ++P++ Sbjct: 182 CSEGVYWMVFKQPIQASVTQLEKMHEYL--------GSNARPVQRQNARTLLKSWPDR 231 >4XIW-A nrPDB Length = 239 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 76/267 (28%), Positives = 121/267 (45%), Gaps = 42/267 (15%) Query: 20 VSDWTYSEGALDEAHWPQHYPACG-GQRQSPINLQRTKVRYNPSLKGLN--MTGYETQAG 76 ++ W Y E A P C G+RQSPIN + N S ++ M ++ G Sbjct: 1 MAAWNYGE----VAGPPTWKGVCATGKRQSPIN-----IPLNTSAPKVDAEMGEFDFAYG 51 Query: 77 EFP---MVNNGH-TVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIR 132 F ++N GH T+Q++ P+ + + + + Q HFH + SEH +DG R Sbjct: 52 SFEKCDVLNTGHGTMQVNFPAGNLAFIGNMELELLQ-FHFH--------APSEHAMDGRR 102 Query: 133 HVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQ 192 + +E H+VH N + LAVL +E +N S + + + Sbjct: 103 YAMEAHLVHKNKSTGN----------LAVLGIMLEPGGLIKNPALSTALEVAPEVPL-AK 151 Query: 193 RTTLTGLDVQDMLPR----NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLE 248 + + G++ +LP+ + + Y GSLTTPPC+E V WFV +K+ +Q+ Sbjct: 152 KPSPKGINPVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFM 211 Query: 249 NSLLDHRNKTIHNDYRRTQPLNHRVVE 275 + D NKT + R Q LN R+VE Sbjct: 212 RFVGD--NKTYATNTRPLQLLNSRLVE 236 >1KOQ-A nrPDB Length = 223 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 101/241 (41%), Gaps = 57/241 (23%) Query: 44 GQRQSPINLQRT--------KVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTM 95 G+ QSP+N+ T KV Y PS+ + NNGHT+Q++ P Sbjct: 28 GKNQSPVNITETVSGKLPAIKVNYKPSMVDVE--------------NNGHTIQVNYPEGG 73 Query: 96 RMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDA 155 +G Y +Q HFH SE+ + G +E H VH + + Sbjct: 74 NTLTVNGRTYTLKQFHFH--------VPSENQIKGRTFPMEAHFVHLDENKQ-------- 117 Query: 156 PDGLAVLAAFVEVKNYPENTYYSNFISHLANIK--YPGQRTTLTGLDVQDMLPRNLQHYY 213 P LAVL E + +S + N+ G+ D +LP+ L+ YY Sbjct: 118 PLVLAVLY---------EAGKTNGRLSSIWNVMPMTAGKVKLNQPFDASTLLPKRLK-YY 167 Query: 214 TYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRV 273 + GSLTTPPCTE V W VL + + + Q K ++ N+ + QPLN RV Sbjct: 168 RFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSENNRPV-------QPLNARV 220 Query: 274 V 274 V Sbjct: 221 V 221 >4TWL-A nrPDB Length = 246 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 64/239 (26%), Positives = 103/239 (43%), Gaps = 31/239 (12%) Query: 38 HYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMR 96 + CG G QSPI L+ +V ++ +L L +A + + N+GH V + Sbjct: 24 EWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRN---YRAVDARLRNSGHDVLVDFKGNAG 80 Query: 97 MTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAP 156 + Y +++HFH S SEH ++G R +E +VH + K ++ Sbjct: 81 SLSINRVEYQLKRIHFH--------SPSEHEMNGERFDLEAQLVHESQDQKRAVVS---- 128 Query: 157 DGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL-TGLDVQDMLPRNLQHYYTY 215 +L F P + +FI +N Q+ + G+ + L + YY Y Sbjct: 129 ----ILFRFGRAD--PFLSDLEDFIKQFSN----SQKNEINAGVVDPNQLQIDDSAYYRY 178 Query: 216 HGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVV 274 GS T PPCTE + W V+ +S QV L+ ++ N+ N+ R QP N R V Sbjct: 179 MGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV----NENAINNARPLQPTNFRSV 233 >4ETQ-X nrPDB Length = 269 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 14/232 (6%) Query: 45 QRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV 104 Q+ SPIN++ K N LK L++ E++ + N G V+I+ Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTT--IQNTGKLVRINFKGGYISGGFLPNE 60 Query: 105 YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYN-SKYKSYDIAQDAPDGLAVLA 163 Y+ +H +WG GS H +D ++ EI++VH+N KY SY+ A+ DGL +++ Sbjct: 61 YVLSSLHIYWGKEDD--YGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 164 AFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQD-MLPRNLQHYYTYHGSLTTP 222 F++V ++ +N Y+ ++ L +I+ + D +LP L Y+TY G TT Sbjct: 119 IFLQVLDH-KNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLD-YFTYLG--TTI 174 Query: 223 PCTENVHWFVLADFVKLSRTQVWKLEN--SLLDHRNKT--IHNDYRRTQPLN 270 + + W + + + Q+ K SL +H K I +YR LN Sbjct: 175 NHSADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLN 226 >6B9J-X nrPDB Length = 241 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 110/232 (47%), Gaps = 14/232 (6%) Query: 45 QRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV 104 Q+ SPIN++ K N LK L++ E++ + N G V+I+ Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTT--IQNTGKLVRINFKGGYISGGFLPNE 60 Query: 105 YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYN-SKYKSYDIAQDAPDGLAVLA 163 Y+ +H +WG + GS H +D ++ EI++VH+N KY SY+ A+ DGL +++ Sbjct: 61 YVLSSLHIYWG--KEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 164 AFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQD-MLPRNLQHYYTYHGSLTTP 222 F++V ++ +N Y+ ++ L +I+ + D +LP L Y+TY G TT Sbjct: 119 IFLQVLDH-KNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLD-YFTYLG--TTI 174 Query: 223 PCTENVHWFVLADFVKLSRTQVWKLEN--SLLDHRNKT--IHNDYRRTQPLN 270 + + W + + + Q+ K SL +H K I +YR LN Sbjct: 175 NHSADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLN 226 >1Y7W-A nrPDB Length = 291 Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 81/286 (28%), Positives = 120/286 (41%), Gaps = 55/286 (19%) Query: 18 QHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPS--------LKGLNMT 69 QH DW L E + YPAC G QSPI++ ++ S L GLN+ Sbjct: 27 QHGFDWP----GLQEGGTTK-YPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVD 81 Query: 70 GYETQAGEFPMVN------NGHTVQISLPSTMRMTVADGTV---YIAQQMHFHWGGASSE 120 G QA + N G V P+ T+ G ++ Q HFH Sbjct: 82 G--AQADGITLTNAKVDLEQGMKVTFDQPAANLPTIEIGGTTKSFVPIQFHFHH------ 133 Query: 121 ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF 180 SEHT++GI + +E+HIV + D A A LAV+ + Y EN F Sbjct: 134 -FLSEHTINGIHYPLELHIV-----MQEQDPADVATAQLAVIGIMYK---YSENG--DAF 182 Query: 181 ISHL----------ANIKYPGQRTTLTGLDVQ-DMLPRNLQHYYTYHGSLTTPPCTENVH 229 ++ L Y ++ ++V+ +LP +L+ Y Y GSLTTP C E V Sbjct: 183 LNSLQTQIEGKIGDGTASYGDTGVSIDNINVKTQLLPSSLK-YAGYDGSLTTPGCDERVK 241 Query: 230 WFVLADFVKLSRTQV-WKLENSLLDHRNKTIHNDYRRTQPLNHRVV 274 W V +++R Q+ ++ ++ H + N+ R Q L R V Sbjct: 242 WHVFTTPREVTREQMKLFVDVTMGAHAGADVVNN-RMIQDLGDREV 286 >3B1B-A nrPDB Length = 377 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/240 (25%), Positives = 101/240 (42%), Gaps = 60/240 (25%) Query: 44 GQRQSPINLQRTKVRYNPSLKGLNMTGYETQ---------AGEFPMVNNGHTVQ------ 88 G++QSPIN+ + +V K N G +TQ ++NNGHT+Q Sbjct: 64 GRKQSPINVPQYQVLDGKGSKIAN--GLQTQWSYPDLMSNGTSVQVINNGHTIQVQWTYN 121 Query: 89 ------ISLPSTMRMT-------------VADGTVYIAQQMHFHWGGASSEISGSEHTVD 129 I++P+ T AD + Q HFH S SEH + Sbjct: 122 YAGHATIAIPAMHNQTNRIVDVLEMRPNDAADRVTAVPTQFHFH--------STSEHLLA 173 Query: 130 GIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKY 189 G + +E+HIVH ++ + +V ++ N P+N +++ Sbjct: 174 GKIYPLELHIVHQVTE----KLEACKGGCFSVTGILFQLDNGPDNELLEPIFANM----- 224 Query: 190 PGQRTTLTGL------DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQ 243 P + T + L + ++LP + + Y TY GSLTTPPC+E + W V+ ++S Q Sbjct: 225 PSREGTFSNLPAGTTIKLGELLPSD-RDYVTYEGSLTTPPCSEGLLWHVMTQPQRISFGQ 283 >3Q31-A nrPDB Length = 244 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 63/207 (30%), Positives = 89/207 (42%), Gaps = 36/207 (17%) Query: 29 ALDEAHWPQHYPACG-GQRQSPINLQRTKVRY--NPSLKGLNMTGYETQAGEFPMVNNGH 85 LDEA+ AC G+ QSPI + + Y + SLK L++ A + N G Sbjct: 24 GLDEAN-----EACAKGKHQSPIVIDSAAIDYAASGSLK-LDLP----LADGSKLENLGF 73 Query: 86 TVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK 145 +Q++L T A+ Y Q HFH + SEH V+ +E+H V Sbjct: 74 GLQVTL--TNGSLTANSKTYTLAQFHFH--------TPSEHHVNEEHFPMEVHFVF---- 119 Query: 146 YKSYDIAQDAPDGLAVLAAFVEVKNYPENT-YYSNFISHLANIKYPGQRTTLTGLDVQDM 204 Q A AV+ F ++ ++ + + + + NI G TT LD + Sbjct: 120 -------QTAAKETAVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTTTGQLDFGGL 172 Query: 205 LPR-NLQHYYTYHGSLTTPPCTENVHW 230 L N Y Y GSLTTPPCTE V W Sbjct: 173 LDHFNRHGVYQYTGSLTTPPCTEEVMW 199 >5TT3-A nrPDB Length = 234 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 60/249 (24%), Positives = 104/249 (41%), Gaps = 40/249 (16%) Query: 21 SDWTYSEGALDEAHWPQ---HYPAC-GGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 76 + W Y W + + C G+ QSPIN++ + + + +A Sbjct: 8 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAV 67 Query: 77 EFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 F HT++ S T + G Y+ +HFH + E ++ + Sbjct: 68 FF----THHTLKASFEPTNHINYR-GHDYVLDNVHFH--------APMEFLINNKTRPLS 114 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLA-AFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 H VH +DA L VLA F E K P N L I+ ++ Sbjct: 115 AHFVH-----------KDAKGRLLVLAIGFEEGKENP------NLDPILEGIQ---KKQN 154 Query: 196 LTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 + + LP+++ +YY ++GSLT PPCTE V WFV+ + +++S Q+ +++ + + Sbjct: 155 FKEVALDAFLPKSI-NYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSP 213 Query: 256 N-KTIHNDY 263 N + + DY Sbjct: 214 NQRPVQPDY 222 >1LW3-A nrPDB Length = 657 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 12/79 (15%) Query: 223 PCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHR---------- 272 P + N+ F ++ ++ WKL + LL++R + I N+ R +N R Sbjct: 188 PVSNNLPLFAF-EYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPAL 246 Query: 273 -VVESNFPNQEYTLGSEFQ 290 VV +N P++E + F+ Sbjct: 247 LVVPANIPDEELKRVASFR 265 >5M3L-D nrPDB Length = 140 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209 DI D P+ + A F V+ +N Y F +H + G T++ LD DML L Sbjct: 34 DIIDDHPE---IKAPFSRVRG--DNIYSPEFGAHSQRV-LSGLDITISMLDTPDMLAAQL 87 Query: 210 QHYYTYHGSLTTPP 223 H H P Sbjct: 88 AHLKVQHVERNLKP 101 >6Q63-A nrPDB Length = 774 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Query: 64 KGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISG 123 +G+ +T T+AG F + T++ SLP + VA V I F + GA ++S Sbjct: 115 QGVTITA-PTEAGVFYGI---QTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSR 170 Query: 124 SEHTVDGIRHVIEIHIVH 141 T+D ++ I++ +H Sbjct: 171 HFFTIDEVKTYIDMLALH 188 >4V93-B0 nrPDB Length = 158 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209 DI D P+ + A F V+ +N Y F +H + G T++ LD DML L Sbjct: 52 DIIDDHPE---IKAPFSRVRG--DNIYSPEFGAHSQRV-LSGLDITISMLDTPDMLAAQL 105 Query: 210 QHYYTYHGSLTTPP 223 H H P Sbjct: 106 AHLKVQHVERNLKP 119 >4M7V-A nrPDB Length = 175 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 11/70 (15%) Query: 245 WKLENSLLDHRNKTIHNDY---RRT------QPLNHRVVESNFPNQEYTLGSEFQFYLHK 295 W L N L + KTIHN R T +PL +R N +Y +E +H Sbjct: 30 WHLPNDLKFFKEKTIHNTLVLGRATFEGMGCRPLPNRTTIVLTSNPDYQ--AEGVLVMHS 87 Query: 296 IEEILDYLRR 305 +EEIL Y + Sbjct: 88 VEEILAYADK 97 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3FE4-A nrPDB 386 e-108 4QK3-A nrPDB 322 2e-88 1Z93-A nrPDB 320 5e-88 1FLJ-A nrPDB 319 7e-88 6G4T-A nrPDB 318 2e-87 4CNR-A nrPDB 316 6e-87 3D0N-A nrPDB 304 3e-83 6FAF-A nrPDB 301 2e-82 5DVX-A nrPDB 300 4e-82 1RJ5-A nrPDB 295 2e-80 4LU3-A nrPDB 293 7e-80 5LL9-A nrPDB 286 7e-78 2W2J-A nrPDB 285 2e-77 1URT-A nrPDB 280 7e-76 5JN8-A nrPDB 266 1e-71 3ZNC-A nrPDB 265 2e-71 4X5S-A nrPDB 251 4e-67 4COQ-A nrPDB 250 7e-67 4G7A-A nrPDB 239 1e-63 6EKI-A nrPDB 236 6e-63 4XZ5-A nrPDB 234 4e-62 5HPJ-A nrPDB 233 9e-62 4XIW-A nrPDB 231 2e-61 1KOQ-A nrPDB 211 3e-55 4ETQ-X nrPDB 211 3e-55 6B9J-X nrPDB 209 1e-54 4TWL-A nrPDB 206 8e-54 1Y7W-A nrPDB 199 1e-51 5TT3-A nrPDB 195 2e-50 3B1B-A nrPDB 170 6e-43 3Q31-A nrPDB 167 6e-42 Sequences not found previously or not previously below threshold: 5TTH-B nrPDB 32 0.24 4N4R-A nrPDB 29 2.2 5HR5-A nrPDB 29 2.8 4D7Q-A nrPDB 29 3.5 4Q35-A nrPDB 29 3.5 1PQ3-A nrPDB 28 4.5 4HGN-A nrPDB 27 7.7 5YI6-A nrPDB 27 8.8 CONVERGED! >3FE4-A nrPDB Length = 278 Score = 386 bits (991), Expect = e-108, Method: Composition-based stats. Identities = 270/271 (99%), Positives = 271/271 (100%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 79 +SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP Sbjct: 1 MSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 60 Query: 80 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI Sbjct: 61 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 120 Query: 140 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL Sbjct: 121 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 180 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 259 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI Sbjct: 181 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 240 Query: 260 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ 290 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ Sbjct: 241 HNDYRRTQPLNHRVVESNFPNQEYTLGSEFQ 271 >4QK3-A nrPDB Length = 249 Score = 322 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 90/262 (34%), Positives = 135/262 (51%), Gaps = 20/262 (7%) Query: 21 SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPM 80 W Y + HW + +P G+RQSP+++ +Y+PSLK L+++ QA + Sbjct: 3 HHWGYGKHN-GPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSY--DQATSLRI 59 Query: 81 VNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 +NNGH + + V G Y Q HFHWG S + GSEHTVD ++ E Sbjct: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWG--SLDGQGSEHTVDKKKYAAE 117 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 +H+VH+N+KY + A PDGLAVL F++V + L +IK G+ Sbjct: 118 LHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG--SAKPGLQKVVDVLDSIKTKGKSADF 175 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 T D + +LP +L Y+TY GSLTTPP E V W VL + + +S QV K + Sbjct: 176 TNFDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLM----- 229 Query: 257 KTIHNDYRRTQPLNHRVVESNF 278 +++R QPL +R ++++F Sbjct: 230 ---VDNWRPAQPLKNRQIKASF 248 >1Z93-A nrPDB Length = 266 Score = 320 bits (820), Expect = 5e-88, Method: Composition-based stats. Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 15/266 (5%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 79 +W Y+ HW + +P G+ QSPI L +R++PSL+ +++ A Sbjct: 2 AKEWGYASHN-GPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKT-- 58 Query: 80 MVNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135 ++NNG T ++ T ++ G Y +Q H HWG SS+ GSEHTVDG+++ Sbjct: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAA 116 Query: 136 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 E+H+VH+N KY ++ A DG+AV+ F+++ + EN + F+ L IK G+ Sbjct: 117 ELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAP 174 Query: 196 LTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 T D + P + + Y+TY GS TTPPC E + W +L + + +S Q+ KL + L Sbjct: 175 FTKFDPSSLFPAS-RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAE 233 Query: 256 NK---TIHNDYRRTQPLNHRVVESNF 278 N+ + +++R QP+N+RVV ++F Sbjct: 234 NEPPVPLVSNWRPPQPINNRVVRASF 259 >1FLJ-A nrPDB Length = 260 Score = 319 bits (818), Expect = 7e-88, Method: Composition-based stats. Identities = 86/266 (32%), Positives = 137/266 (51%), Gaps = 15/266 (5%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP 79 +W Y+ HW + YP G QSPI L +R++PSL+ +++ A Sbjct: 2 AKEWGYASHN-GPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKT-- 58 Query: 80 MVNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135 ++NNG T ++ T ++ G Y +Q H HWG SS+ GSEHTVDG+++ Sbjct: 59 ILNNGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAA 116 Query: 136 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 E+H+VH+N KY ++ A PDG+AV+ F+++ E + + L IK G+ Sbjct: 117 ELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGR--EKGEFQILLDALDKIKTKGKEAP 174 Query: 196 LTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 D + P + Y+TYHGS TTPPC E + W +L + + +S Q+ KL + Sbjct: 175 FNHFDPSCLFPA-CRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAE 233 Query: 256 NK---TIHNDYRRTQPLNHRVVESNF 278 N+ + ++R QP+ RVV ++F Sbjct: 234 NEPPVPLVGNWRPPQPIKGRVVRASF 259 >6G4T-A nrPDB Length = 274 Score = 318 bits (814), Expect = 2e-87, Method: Composition-based stats. Identities = 93/266 (34%), Positives = 143/266 (53%), Gaps = 16/266 (6%) Query: 21 SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPM 80 W Y + +HW + YP G RQSPIN+ ++ Y+PSL+ L ++ + Sbjct: 7 HGWGYGQDD-GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSY--EACMSLSI 63 Query: 81 VNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 NNGH+VQ+ + TV G Y +Q HFHWG GSEHTVDG E Sbjct: 64 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKK--HDVGSEHTVDGKSFPSE 121 Query: 137 IHIVHYN-SKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 +H+VH+N KY ++ A APDGLAV+ F+E + E+ + L +++ G + Sbjct: 122 LHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQ 179 Query: 196 LTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 + + + +LP + +HY+TY GSLTTPP +E+V W VL + + +S Q+ K + L Sbjct: 180 FSCFNPKSLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSE 238 Query: 256 NKT---IHNDYRRTQPLNHRVVESNF 278 + + N++R QPL RVV+++F Sbjct: 239 DDERIHMVNNFRPPQPLKGRVVKASF 264 >4CNR-A nrPDB Length = 262 Score = 316 bits (810), Expect = 6e-87, Method: Composition-based stats. Identities = 91/266 (34%), Positives = 134/266 (50%), Gaps = 16/266 (6%) Query: 21 SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPM 80 W Y + HW + +P G+RQSP+++ V +P+LK L + E A M Sbjct: 5 HHWGYDKHN-GPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGE--ATSRRM 61 Query: 81 VNNGHTVQISLPSTMRMTVAD----GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 VN+GH+ + + V Y Q HFHWG SS+ GSEHTVD ++ E Sbjct: 62 VNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWG--SSDDQGSEHTVDRKKYAAE 119 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 +H+VH+N+KY + A PDGLAV+ F++V + N + L +IK G+ T Sbjct: 120 LHLVHWNTKYGDFGTAAQEPDGLAVVGVFLKVGD--ANPALQKVLDALDSIKTKGKSTDF 177 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 D +LP N+ Y+TY GSLTTPP E+V W VL + + +S Q+ K + Sbjct: 178 PNFDPGSLLP-NVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEG 236 Query: 257 KT---IHNDYRRTQPLNHRVVESNFP 279 + + ++R QPL +R V FP Sbjct: 237 EPEELMLANWRPAQPLKNRQVR-GFP 261 >3D0N-A nrPDB Length = 264 Score = 304 bits (779), Expect = 3e-83, Method: Composition-based stats. Identities = 90/264 (34%), Positives = 142/264 (53%), Gaps = 16/264 (6%) Query: 23 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82 W Y E HW + +P G +QSPI ++ +V+Y+ SL+ L++ Y+ + + + N Sbjct: 8 WGYREHN-GPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIK-YDPSSAKI-ISN 64 Query: 83 NGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 +GH+ + T +V G Y +Q+H HWG S++ GSEH VDG+ + E+H Sbjct: 65 SGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWG--SADDHGSEHIVDGVSYAAELH 122 Query: 139 IVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 +VH+NS KY S+ A PDGLAVL F+++ N+ L +IK G++T T Sbjct: 123 VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEP--NSQLQKITDTLDSIKEKGKQTRFT 180 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK 257 D+ +LP + Y+TY GSLT PP E+V W VL + +S Q+ K + L + Sbjct: 181 NFDLLSLLPPSW-DYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGE 239 Query: 258 T---IHNDYRRTQPLNHRVVESNF 278 + +++R QPL R V ++F Sbjct: 240 AAAFLVSNHRPPQPLKGRKVRASF 263 >6FAF-A nrPDB Length = 261 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 84/265 (31%), Positives = 135/265 (50%), Gaps = 16/265 (6%) Query: 22 DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81 DW Y + W + YP G QSP++++ ++ +++ SLK ++++ A E ++ Sbjct: 5 DWGYDDKN-GPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61 Query: 82 NNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137 N GH+ ++ +V G Y Q HFHWG S+ GSEHTVDG+++ E+ Sbjct: 62 NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWG--STNEHGSEHTVDGVKYSAEL 119 Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 H+ H+NS KY S A DGLAV+ ++V N + L IK G+R Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 T D +LP +L ++TY GSLT PP E+V W + + + +S Q+ + + L + Sbjct: 178 TNFDPSTLLPSSL-DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236 Query: 257 K---TIHNDYRRTQPLNHRVVESNF 278 + ++ R TQPL R V ++F Sbjct: 237 DNAVPMQHNNRPTQPLKGRTVRASF 261 >5DVX-A nrPDB Length = 260 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 104/259 (40%), Positives = 149/259 (57%), Gaps = 8/259 (3%) Query: 22 DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA-GEFPM 80 W Y + WP+ PAC G+ QSP++++ ++P+L+ L ++G++ E + Sbjct: 1 HWRYG----GDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRL 56 Query: 81 VNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140 NNGH+VQ++LP + M + G Y A Q+H HWG A GSEHTV+G R EIH+V Sbjct: 57 RNNGHSVQLTLPPGLEMKLGPGREYRALQLHLHWGAAGRP--GSEHTVEGHRFPAEIHVV 114 Query: 141 HYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLD 200 H ++KY D A P GLAVLAAF+E EN+ Y +S L I G T + GLD Sbjct: 115 HLSTKYARVDEALGRPGGLAVLAAFLEEGP-EENSAYEQLLSRLEEIAEEGSETQVPGLD 173 Query: 201 VQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIH 260 + +LP + Y+ Y GSLTTPPC + V W V V LS Q+ L ++L + + Sbjct: 174 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGDSRLQ 233 Query: 261 NDYRRTQPLNHRVVESNFP 279 ++R TQPLN RV+E++FP Sbjct: 234 LNFRATQPLNGRVIEASFP 252 >1RJ5-A nrPDB Length = 261 Score = 295 bits (755), Expect = 2e-80, Method: Composition-based stats. Identities = 102/264 (38%), Positives = 149/264 (56%), Gaps = 9/264 (3%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGE-F 78 WTY EG + HWP YP CGG QSPIN+Q V ++P L + GY+ E Sbjct: 2 GHHWTY-EGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPL 60 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 + NNGHTVQ+SLP T+ + Y A Q+H HWG S GSEH ++ E+H Sbjct: 61 DLHNNGHTVQLSLPPTLHLGGL-PRKYTAAQLHLHWGQRGSLE-GSEHHINSEATAAELH 118 Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 +VHY+S+ Y S A P GLAVL +EV EN Y + +S L I+Y Q+T++ Sbjct: 119 VVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGET-ENPAYDHILSRLHEIRYKDQKTSVP 177 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL---DH 254 V+++ P+ L+ ++ Y+GSLTTPPC ++V W V ++S Q+ KL+ +L + Sbjct: 178 PFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEED 237 Query: 255 RNKTIHNDYRRTQPLNHRVVESNF 278 ++ + +YR QPLN R + ++F Sbjct: 238 PSEPLVQNYRVPQPLNQRTIFASF 261 >4LU3-A nrPDB Length = 279 Score = 293 bits (750), Expect = 7e-80, Method: Composition-based stats. Identities = 106/274 (38%), Positives = 154/274 (56%), Gaps = 11/274 (4%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGE-F 78 WTY EG + HWP YP CG QSPI++Q V ++P L L GY+ E Sbjct: 4 GQHWTY-EGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPL 62 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 + NNGHTVQ+SLPST+ + Y+A Q+H HWG S GSEH ++ E+H Sbjct: 63 DLHNNGHTVQLSLPSTLYLGGL-PRKYVAAQLHLHWGQKGSPG-GSEHQINSEATFAELH 120 Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 IVHY+S Y S A + P GLAVL +EV +N Y + +SHL +++ Q+T++ Sbjct: 121 IVHYDSDSYDSLSEAAERPQGLAVLGILIEVGET-KNIAYEHILSHLHEVRHKDQKTSVP 179 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK 257 +++++LP+ L Y+ Y+GSLTTPPC ++V W V ++S Q+ KL+ +L + Sbjct: 180 PFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEE 239 Query: 258 T---IHNDYRRTQPLNHRVVESNF--PNQEYTLG 286 + +YR QPLN R+V ++F YT G Sbjct: 240 PSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTG 273 >5LL9-A nrPDB Length = 263 Score = 286 bits (732), Expect = 7e-78, Method: Composition-based stats. Identities = 104/266 (39%), Positives = 151/266 (56%), Gaps = 12/266 (4%) Query: 20 VSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA-GEF 78 +S WTY G E W + YP+CGG QSPI+L ++Y+ SL L GY A +F Sbjct: 1 MSKWTYF-GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQF 59 Query: 79 PMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138 + NNGH+V+++LPS M + Y A Q+H HWG + + GSEHTV G E+H Sbjct: 60 LLTNNGHSVKLNLPSDMHIQGLQS-RYSATQLHLHWGNPN-DPHGSEHTVSGQHFAAELH 117 Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 IVHYNS Y A + +GLAVLA +E+ ++ N Y SHL ++KY GQ + Sbjct: 118 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF--NPSYDKIFSHLQHVKYKGQEAFVP 175 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL----- 252 G +++++LP YY Y GSLTTPPC V W V + V++S+ Q+ LE +L Sbjct: 176 GFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMD 235 Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278 D + + N++R+ Q + R+V ++F Sbjct: 236 DPSPREMINNFRQVQKFDERLVYTSF 261 >2W2J-A nrPDB Length = 291 Score = 285 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 134/258 (51%), Gaps = 17/258 (6%) Query: 34 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93 W +P G+ QSPINL + RY+PSL + ++ + + N+GHT+Q+ L S Sbjct: 37 EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS 96 Query: 94 TMRMTVAD---GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKSY 149 ++ G + ++ FHWG + GSEHTV+ +E+H++H+NS + S Sbjct: 97 KSVLSGGPLPQGHEFELYEVRFHWGRENQR--GSEHTVNFKAFPMELHLIHWNSTLFGSI 154 Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRN- 208 D A P G+A++A FV++ E+ L +I+Y G+ T+ + +LP Sbjct: 155 DEAVGKPHGIAIIALFVQIGK--EHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPL 212 Query: 209 LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENS--------LLDHRNKTIH 260 L+ Y+ Y GSLT PPC+E V W + + +S+ Q+ + L++ + + Sbjct: 213 LRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILG 272 Query: 261 NDYRRTQPLNHRVVESNF 278 +++R TQPL+ RV+ + F Sbjct: 273 DNFRPTQPLSDRVIRAAF 290 >1URT-A nrPDB Length = 248 Score = 280 bits (715), Expect = 7e-76, Method: Composition-based stats. Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 15/246 (6%) Query: 41 ACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVA 100 + G RQSPIN+Q Y+P L L ++ Y+ + + + N GH Q+ + + Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAPLRVS-YDAASCRY-LWNTGHAFQVEFDDSCEDSGI 58 Query: 101 DGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNS-KYKSYDIAQDA 155 G Y +Q HFHWG +++ GSEH VDG + E+H+VH+NS KY++Y A Sbjct: 59 SGGPLGNHYRLKQFHFHWG--ATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVG 116 Query: 156 PDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTY 215 +GLAV+ F+++ + + + L +++ + + D ++P + Y+TY Sbjct: 117 ENGLAVIGVFLKLGAH--HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPA-CRDYWTY 173 Query: 216 HGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK---TIHNDYRRTQPLNHR 272 GSLTTPP E+V W V V++S +Q+ L R + + N+YR QPL R Sbjct: 174 PGSLTTPPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDR 233 Query: 273 VVESNF 278 + S+F Sbjct: 234 KLRSSF 239 >5JN8-A nrPDB Length = 266 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 88/269 (32%), Positives = 131/269 (48%), Gaps = 17/269 (6%) Query: 21 SDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA 75 S W Y E + +++P P C RQSPIN+ TK + + L +GY+ + Sbjct: 3 SHWCY-EVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 76 GEFPMVNNGHTVQISLPSTMRMTVAD-GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHV 134 + + NNGH+V + L + ++ Y A+Q+H HW GSEH++DG Sbjct: 62 T-WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWS--DLPYKGSEHSLDGEHFA 118 Query: 135 IEIHIVHYNSKYKS--YDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQ 192 +E+HIVH K S AQD D +AVLA VE N + + L+NI P Sbjct: 119 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQV-NEGFQPLVEALSNIPKPEM 177 Query: 193 RTTLTGLDVQDMLPR--NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENS 250 TT+ + D+LP+ L+HY+ Y GSLTTP C E V W V + ++L R Q+ Sbjct: 178 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 237 Query: 251 LLDHRNKT--IHNDYRRTQPLNHRVVESN 277 L + +T + ++ R Q L R V + Sbjct: 238 LYYDKEQTVSMKDNVRPLQQLGQRTVIKS 266 >3ZNC-A nrPDB Length = 258 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 84/264 (31%), Positives = 131/264 (49%), Gaps = 17/264 (6%) Query: 23 WTY---SEGALDEAHWPQHYP-ACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEF 78 W Y +E P+ +P AC +QSPIN+ + + NP L + GY+ Q ++ Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD-QKQQW 59 Query: 79 PMVNNGHTVQISLPSTMRMTVAD-GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137 P+ NN HTV+++L + D Y A Q+H HW + GSEH++DG +E+ Sbjct: 60 PIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDN--GSEHSIDGRHFAMEM 117 Query: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 HIVH K +D+ D AVLA +EV + N + + L +I P +T+ Sbjct: 118 HIVHK----KLTSSKEDSKDKFAVLAFMIEVGDKV-NKGFQPLVEALPSISKPHSTSTVR 172 Query: 198 GLDVQDMLPRNLQHY--YTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR 255 +QDMLP + + Y + Y+GSLTTP C E V W V +K+ + Q + +L Sbjct: 173 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 232 Query: 256 NK--TIHNDYRRTQPLNHRVVESN 277 ++ + ++ R QPL R V + Sbjct: 233 DQKLNMKDNVRPLQPLGKRQVFKS 256 >4X5S-A nrPDB Length = 232 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 75/267 (28%), Positives = 127/267 (47%), Gaps = 39/267 (14%) Query: 14 GGQAQHVSDWTYSEGALDEAHWPQHYPA---CGGQRQSPINLQRTKVRYNPSLKGLNMTG 70 G V W+Y EG +W + P C + QSP+++ + + L+ L++ Sbjct: 1 GSHMAEVHHWSY-EGENGPENWAKLNPEYFWCNLKNQSPVDISDN-YKVHAKLEKLHINY 58 Query: 71 YETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDG 130 + E +VNNGHT+Q+++ ++ + G Y +Q HFH + SEHTV+G Sbjct: 59 NKAVNPE--IVNNGHTIQVNVLEDFKLNI-KGKEYHLKQFHFH--------APSEHTVNG 107 Query: 131 IRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 190 + +E+H+VH +D +AV+ F + N + +K Sbjct: 108 KYYPLEMHLVH-----------KDKDGNIAVIGVFFKEGK--ANPELDKVFKN--ALKEE 152 Query: 191 GQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENS 250 G + +++ +LP +++YYTY GSLTTPPCTE V W VL + S+ Q+ ++ Sbjct: 153 GSKVFDGSININALLPP-VKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSI 211 Query: 251 LLDHRNKTIHNDYRRTQPLNHRVVESN 277 + HN+ R TQP+N R + + Sbjct: 212 MK-------HNNNRPTQPINSRYILES 231 >4COQ-A nrPDB Length = 247 Score = 250 bits (638), Expect = 7e-67, Method: Composition-based stats. Identities = 81/258 (31%), Positives = 114/258 (44%), Gaps = 42/258 (16%) Query: 22 DWTYSEGALDEAHWPQHYPA---CG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGE 77 W YS G++ HW P C G+ QSPI++ L +++ + Sbjct: 25 HWGYS-GSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAPVSVYY---VSDA 79 Query: 78 FPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137 +VNNGHT+++ + V DG + +Q HFH + SEHTV+G + E Sbjct: 80 KYVVNNGHTIKVVM-GGRGYVVVDGKRFYLKQFHFH--------APSEHTVNGKHYPFEA 130 Query: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 H VH D + VL F +V EN + PGQ+ LT Sbjct: 131 HFVHL-----------DKNGNITVLGVFFKVGK--ENPELEKVWRVMPE--EPGQKRHLT 175 Query: 198 G-LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 +D + +LP N + YY Y GSLTTPPC+E V W V + V++SR Q+ K + N Sbjct: 176 ARIDPEKLLPEN-RDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNN 234 Query: 257 KTIHNDYRRTQPLNHRVV 274 R QPLN R V Sbjct: 235 -------RPVQPLNARKV 245 >4G7A-A nrPDB Length = 248 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 77/268 (28%), Positives = 123/268 (45%), Gaps = 40/268 (14%) Query: 14 GGQAQHVSDWTYSEGALDEAHWPQHYPA---CGGQRQSPINLQRTKVRYNPSLKGLNMTG 70 G +W+Y EG HW Q P C + QSPIN+ K + +L LN+ Sbjct: 18 GSHMLE-HEWSY-EGEKGPEHWAQLKPEFFWCKLKNQSPINID-KKYKVKANLPKLNL-- 72 Query: 71 YETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDG 130 Y A E +VNNGHT+QI++ + G Y +Q HFH + SEHT++ Sbjct: 73 YYKTAKESEVVNNGHTIQINIKEDNTLNYL-GEKYQLKQFHFH--------TPSEHTIEK 123 Query: 131 IRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 190 + +EIH VH + + V+ ++ N ++ Sbjct: 124 KSYPLEIHFVH-----------KTEDGKILVVGVMAKLGKT--NKELDKILNVAPA--EE 168 Query: 191 GQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENS 250 G++ L++ +++P++ + Y TY GSLTTPPCTE V W VL + +S+ Q+ KL++ Sbjct: 169 GEKILDKNLNLNNLIPKD-KRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSV 227 Query: 251 LLDHRNKTIHNDYRRTQPLNHRVVESNF 278 +++ N R Q +N R + F Sbjct: 228 MVNPNN-------RPVQEINSRWIIEGF 248 >6EKI-A nrPDB Length = 226 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 73/260 (28%), Positives = 113/260 (43%), Gaps = 45/260 (17%) Query: 20 VSDWTYSEGALDEAHWPQH---YPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQA 75 V W+Y G HW Y C G+ QSP+++ R L+ + + + Sbjct: 3 VGHWSY-HGETGPQHWGDLKNEYIMCKIGKNQSPVDISR---IVEAELEKIKINY---SS 55 Query: 76 GEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135 G + NNGHT+++S + + DG + +Q HFH + SEHT+ G + Sbjct: 56 GGSSITNNGHTIKVSYEPGSYI-IVDGIRFELKQFHFH--------APSEHTIKGKSYPF 106 Query: 136 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 E H VH D LAV+ + +N +L G+ Sbjct: 107 EAHFVH-----------ADKDGNLAVIGVIFKEGK--KNPIIEKIWENL---PEAGKTIK 150 Query: 196 LT-GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDH 254 L ++ D+LP+ + YY Y GSLTTPPC+E V W V+ + ++LS+ Q+ K + Sbjct: 151 LAHKINAYDLLPKK-KKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGGD 209 Query: 255 RNKTIHNDYRRTQPLNHRVV 274 N R QPLN R++ Sbjct: 210 TN-------RPVQPLNARMI 222 >4XZ5-A nrPDB Length = 233 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 73/264 (27%), Positives = 115/264 (43%), Gaps = 39/264 (14%) Query: 22 DWTYSEGALDEAHWPQHYPA---CG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGE 77 W Y G +W + P C G+ QSPINL+ SL G ++ E Sbjct: 3 HWGYF-GEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRE---TA 58 Query: 78 FPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137 ++NNGHT+Q+++P + + +G Y Q HFH + SEH DG + +E+ Sbjct: 59 LKLINNGHTLQVNIPLGSYIKI-NGHRYELLQYHFH--------TPSEHQRDGFNYPMEM 109 Query: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197 H+VH +D LAV+A + EN + +S L + Sbjct: 110 HLVH-----------KDGDGNLAVIAILFQEGE--ENETLAKLMSFLPQTLKKQEIHESV 156 Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK 257 + P + + +Y Y GSLTTPPC+E V+W V ++ S TQ+ K+ L Sbjct: 157 KIHPAKFFPAD-KKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGS---- 211 Query: 258 TIHNDYRRTQPLNHRVVESNFPNQ 281 + R Q N R + ++P++ Sbjct: 212 ----NARPVQRQNARTLLKSWPDR 231 >5HPJ-A nrPDB Length = 217 Score = 233 bits (594), Expect = 9e-62, Method: Composition-based stats. Identities = 83/255 (32%), Positives = 124/255 (48%), Gaps = 42/255 (16%) Query: 22 DWTYSEGALDEAHWPQHYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPM 80 +W+Y+ G HW + C G Q+PI++ +T L L++ YE Q E + Sbjct: 1 EWSYT-GEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHLD-YEGQVTE--L 53 Query: 81 VNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140 VNNGHT+Q +L +TV DG + +Q HFH + SE+ + G ++ +E H V Sbjct: 54 VNNGHTIQANLTGKNTLTV-DGKTFELKQFHFH--------TPSENYLKGKQYPLEAHFV 104 Query: 141 HYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG-L 199 H K LAV+A + N + LA+I GQ L L Sbjct: 105 HATDK-----------GELAVVAVMFDFGPRSNNE----LTTLLASIPSKGQTVELKEAL 149 Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 259 + D+LPR+ + YY ++GSLTTPPC+E V WFV+ + S+ Q KL+ + Sbjct: 150 NPADLLPRD-REYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQAVMG------- 201 Query: 260 HNDYRRTQPLNHRVV 274 N+ R QPLN R++ Sbjct: 202 -NNARPLQPLNARLI 215 >4XIW-A nrPDB Length = 239 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 71/264 (26%), Positives = 117/264 (44%), Gaps = 36/264 (13%) Query: 20 VSDWTYSEGALDEAHWPQHYPACG-GQRQSPINL--QRTKVRYNPSLKGLNMTGYETQAG 76 ++ W Y E A P C G+RQSPIN+ + + + + + + Sbjct: 1 MAAWNYGEVAGP----PTWKGVCATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFE-- 54 Query: 77 EFPMVNNGH-TVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135 + ++N GH T+Q++ P+ + + + Q HFH + SEH +DG R+ + Sbjct: 55 KCDVLNTGHGTMQVNFPAGNLAFIGNMEL-ELLQFHFH--------APSEHAMDGRRYAM 105 Query: 136 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 195 E H+VH N LAVL +E +N S + + ++ + Sbjct: 106 EAHLVHKNKS----------TGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLA-KKPS 154 Query: 196 LTGLDVQDMLPRN----LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSL 251 G++ +LP+ + + Y GSLTTPPC+E V WFV +K+ +Q+ + Sbjct: 155 PKGINPVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFV 214 Query: 252 LDHRNKTIHNDYRRTQPLNHRVVE 275 D NKT + R Q LN R+VE Sbjct: 215 GD--NKTYATNTRPLQLLNSRLVE 236 >1KOQ-A nrPDB Length = 223 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 105/258 (40%), Gaps = 42/258 (16%) Query: 21 SDWTYSEGALDEAHWP---QHYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 76 + W Y+ G W + + C G+ QSP+N+ T + L + + + Sbjct: 2 THWGYT-GHDSPESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVNY---KPS 54 Query: 77 EFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 + NNGHT+Q++ P +G Y +Q HFH SE+ + G +E Sbjct: 55 MVDVENNGHTIQVNYPEGGNTLTVNGRTYTLKQFHFH--------VPSENQIKGRTFPME 106 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 H VH + + VLA E N S+ + + G+ Sbjct: 107 AHFVHLDENKQPL-----------VLAVLYEAGKT--NGRLSSIWNVMP--MTAGKVKLN 151 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 D +LP+ L+ YY + GSLTTPPCTE V W VL + + + Q K ++ N Sbjct: 152 QPFDASTLLPKRLK-YYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSENN 210 Query: 257 KTIHNDYRRTQPLNHRVV 274 R QPLN RVV Sbjct: 211 -------RPVQPLNARVV 221 >4ETQ-X nrPDB Length = 269 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 109/233 (46%), Gaps = 14/233 (6%) Query: 45 QRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV 104 Q+ SPIN++ K N LK L++ E++ + N G V+I+ Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTT--IQNTGKLVRINFKGGYISGGFLPNE 60 Query: 105 YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYN-SKYKSYDIAQDAPDGLAVLA 163 Y+ +H +WG + GS H +D ++ EI++VH+N KY SY+ A+ DGL +++ Sbjct: 61 YVLSSLHIYWGKE--DDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 164 AFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG-LDVQDMLPRNLQHYYTYHGSLTTP 222 F++V ++ +N Y+ ++ L +I+ + ++LP L Y+TY G TT Sbjct: 119 IFLQVLDH-KNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKL-DYFTYLG--TTI 174 Query: 223 PCTENVHWFVLADFVKLSRTQVWKLENS--LLDHRNKT--IHNDYRRTQPLNH 271 + + W + + + Q+ K L +H K I +YR LN Sbjct: 175 NHSADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >6B9J-X nrPDB Length = 241 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 109/233 (46%), Gaps = 14/233 (6%) Query: 45 QRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV 104 Q+ SPIN++ K N LK L++ E++ + N G V+I+ Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTT--IQNTGKLVRINFKGGYISGGFLPNE 60 Query: 105 YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYN-SKYKSYDIAQDAPDGLAVLA 163 Y+ +H +WG + GS H +D ++ EI++VH+N KY SY+ A+ DGL +++ Sbjct: 61 YVLSSLHIYWGKE--DDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 164 AFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG-LDVQDMLPRNLQHYYTYHGSLTTP 222 F++V ++ +N Y+ ++ L +I+ + ++LP L Y+TY G TT Sbjct: 119 IFLQVLDH-KNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKL-DYFTYLG--TTI 174 Query: 223 PCTENVHWFVLADFVKLSRTQVWKLENS--LLDHRNKT--IHNDYRRTQPLNH 271 + + W + + + Q+ K L +H K I +YR LN Sbjct: 175 NHSADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4TWL-A nrPDB Length = 246 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 37/261 (14%) Query: 22 DWTYSEG-ALDEAHWPQH---YPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 76 +++Y +G +W + CG G QSPI L+ +V ++ +L L +A Sbjct: 4 EFSYIDGNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNY---RAV 60 Query: 77 EFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 + + N+GH V + + Y +++HFH S SEH ++G R +E Sbjct: 61 DARLRNSGHDVLVDFKGNAGSLSINRVEYQLKRIHFH--------SPSEHEMNGERFDLE 112 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK-NYPENTYYSNFISHLANIKYPGQRTT 195 +VH + K AV++ P + +FI +N Q+ Sbjct: 113 AQLVHESQDQKR-----------AVVSILFRFGRADPFLSDLEDFIKQFSN----SQKNE 157 Query: 196 L-TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDH 254 + G+ + L + YY Y GS T PPCTE + W V+ +S QV L+ ++ Sbjct: 158 INAGVVDPNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV--- 214 Query: 255 RNKTIHNDYRRTQPLNHRVVE 275 N+ N+ R QP N R V Sbjct: 215 -NENAINNARPLQPTNFRSVF 234 >1Y7W-A nrPDB Length = 291 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 76/290 (26%), Positives = 114/290 (39%), Gaps = 55/290 (18%) Query: 16 QAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPS--------LKGLN 67 QH DW + YPAC G QSPI++ ++ S L GLN Sbjct: 25 YMQHGFDW-----PGLQEGGTTKYPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLN 79 Query: 68 MTGYETQAGEFPMVN------NGHTVQISLPSTMRMTVADGTV---YIAQQMHFHWGGAS 118 + G QA + N G V P+ T+ G ++ Q HFH Sbjct: 80 VDG--AQADGITLTNAKVDLEQGMKVTFDQPAANLPTIEIGGTTKSFVPIQFHFHH---- 133 Query: 119 SEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYS 178 SEHT++GI + +E+HIV + D A A LAV+ + Sbjct: 134 ---FLSEHTINGIHYPLELHIV-----MQEQDPADVATAQLAVIGIMYKYSENG-----D 180 Query: 179 NFISHLAN----------IKYPGQRTTLTGLDVQD-MLPRNLQHYYTYHGSLTTPPCTEN 227 F++ L Y ++ ++V+ +LP +L+ Y Y GSLTTP C E Sbjct: 181 AFLNSLQTQIEGKIGDGTASYGDTGVSIDNINVKTQLLPSSLK-YAGYDGSLTTPGCDER 239 Query: 228 VHWFVLADFVKLSRTQVWKL-ENSLLDHRNKTIHNDYRRTQPLNHRVVES 276 V W V +++R Q+ + ++ H + N+ R Q L R V Sbjct: 240 VKWHVFTTPREVTREQMKLFVDVTMGAHAGADVVNN-RMIQDLGDREVYK 288 >5TT3-A nrPDB Length = 234 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 58/261 (22%), Positives = 105/261 (40%), Gaps = 43/261 (16%) Query: 21 SDWTYSEGALDEAHW---PQHYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 76 + W Y W + + C G+ QSPIN++ + + + +A Sbjct: 8 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAV 67 Query: 77 EFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIE 136 F HT++ S T + G Y+ +HFH + E ++ + Sbjct: 68 FF----THHTLKASFEPTNHINY-RGHDYVLDNVHFH--------APMEFLINNKTRPLS 114 Query: 137 IHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196 H VH +DA L VLA E EN + + ++ Sbjct: 115 AHFVH-----------KDAKGRLLVLAIGFEEGK--ENPNLDPILEGIQ------KKQNF 155 Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN 256 + + LP+++ +YY ++GSLT PPCTE V WFV+ + +++S Q+ +++ + + N Sbjct: 156 KEVALDAFLPKSI-NYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPN 214 Query: 257 KTIHNDYRRTQPLNHRVVESN 277 + R QP + V+ + Sbjct: 215 Q------RPVQPDYNTVIIKS 229 >3B1B-A nrPDB Length = 377 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 53/269 (19%) Query: 22 DWTYS---EGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLK-------GLNMTGY 71 W + E + + G++QSPIN+ + +V K + Sbjct: 39 HWDHGLNGENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQTQWSYPDL 98 Query: 72 ETQAGEFPMVNNGHTVQI------------SLPSTMRMT-------------VADGTVYI 106 + ++NNGHT+Q+ ++P+ T AD + Sbjct: 99 MSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAADRVTAV 158 Query: 107 AQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFV 166 Q HFH S SEH + G + +E+HIVH ++ + +V Sbjct: 159 PTQFHFH--------STSEHLLAGKIYPLELHIVHQVTE----KLEACKGGCFSVTGILF 206 Query: 167 EVKNYPENTYYSNFISHLANIKYPGQRTTLTG---LDVQDMLPRNLQHYYTYHGSLTTPP 223 ++ N P+N +++ + G + L + + ++LP + + Y TY GSLTTPP Sbjct: 207 QLDNGPDNELLEPIFANMPS--REGTFSNLPAGTTIKLGELLPSD-RDYVTYEGSLTTPP 263 Query: 224 CTENVHWFVLADFVKLSRTQVWKLENSLL 252 C+E + W V+ ++S Q + ++ Sbjct: 264 CSEGLLWHVMTQPQRISFGQWNRYRLAVG 292 >3Q31-A nrPDB Length = 244 Score = 167 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 66/261 (25%), Positives = 103/261 (39%), Gaps = 41/261 (15%) Query: 14 GGQAQHVSDWTYSEGALDEAHW---PQHYPAC-GGQRQSPINLQRTKVRYNPS-LKGLNM 68 G + + Y+ G +W + AC G+ QSPI + + Y S L++ Sbjct: 2 AGGLDDANKFNYT-GLGGPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAASGSLKLDL 60 Query: 69 TGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTV 128 A + N G +Q++L T A+ Y Q HFH + SEH V Sbjct: 61 ----PLADGSKLENLGFGLQVTL--TNGSLTANSKTYTLAQFHFH--------TPSEHHV 106 Query: 129 DGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPEN-TYYSNFISHLANI 187 + +E+H V Q A AV+ F ++ ++ + + + + NI Sbjct: 107 NEEHFPMEVHFVF-----------QTAAKETAVVGFFFQLSEVGDSVPLFDSVFAPIDNI 155 Query: 188 KYPGQRTTLTGLDVQDMLPR-NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK 246 G TT LD +L N Y Y GSLTTPPCTE V W + + + L+ K Sbjct: 156 PDAGTSTTTGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNK 215 Query: 247 LENSLLDHRNKTIHNDYRRTQ 267 ++ + + R TQ Sbjct: 216 VKKIIKY--------NARYTQ 228 >5TTH-B nrPDB Length = 672 Score = 32.4 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 26/75 (34%), Gaps = 9/75 (12%) Query: 229 HWFVLADFVKLSRTQVWKLENSLLDHRNKT-IHNDYRRTQPLNHRVV------ESNFPNQ 281 W + + +S Q + + +K YR PLN R + + + + Sbjct: 247 LW--MMEPKDISEWQHEEFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYVPEMKPSMFDV 304 Query: 282 EYTLGSEFQFYLHKI 296 +GS Y KI Sbjct: 305 SREMGSSVALYSRKI 319 >4N4R-A nrPDB Length = 786 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 216 HGSLTTPPCTENV-HWFVL-ADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRV 273 +GS T+ C W V+ ++ + QV ++ N+ I P+ + Sbjct: 167 NGSFTS--CLPGSDTWSVVGSEVIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKR 224 Query: 274 VESNF--PNQEYTLGSEFQFYL 293 S F PN +YT + F+FYL Sbjct: 225 -RSGFLIPNAKYTTKNYFEFYL 245 >5HR5-A nrPDB Length = 531 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 25/182 (13%), Positives = 52/182 (28%), Gaps = 29/182 (15%) Query: 52 LQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMH 111 ++ KV Y + L+ ++ ++N G ++ + VY +H Sbjct: 195 IECYKVTY----QPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKI---VYYLMNIH 247 Query: 112 FHWGGASSEISG-SEH------------TVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDG 158 H G SE +V G + + K+ D Sbjct: 248 VHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQAL------RKFLEEQEIADLKVW 301 Query: 159 LAVLAAFVEVKNYPENTYYS-NFISHLA-NIKYPGQRTTLTGLDVQDMLPRNLQHY-YTY 215 + L ++ TY ++ + + + + R+ + Y Y Y Sbjct: 302 TSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRY 361 Query: 216 HG 217 G Sbjct: 362 PG 363 >4D7Q-A nrPDB Length = 352 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 27/69 (39%), Gaps = 1/69 (1%) Query: 131 IRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 190 E++ V + Y+ +I+ L F+E K +N + ++ I++ Sbjct: 194 KAKPFELNFVDSSPGYQINNISSQNDKTFKQLNQFLEEKRNIQNI-FPKLQNNNLTIEFK 252 Query: 191 GQRTTLTGL 199 +T L+ Sbjct: 253 NPKTFLSKF 261 >4Q35-A nrPDB Length = 802 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 216 HGSLTTPPCTENV-HWFVL-ADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRV 273 +GS T+ C W V+ ++ + QV ++ N+ I P+ + Sbjct: 167 NGSFTS--CLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKR 224 Query: 274 VESNF--PNQEYTLGSEFQFYL 293 S F PN +YT + F+FYL Sbjct: 225 -RSGFLIPNAKYTTTNYFEFYL 245 >1PQ3-A nrPDB Length = 306 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 19/48 (39%), Gaps = 7/48 (14%) Query: 44 GQRQSPINLQRTKVRYNPSLKGLN-------MTGYETQAGEFPMVNNG 84 G+RQ PI+L ++P+L +T E + N G Sbjct: 217 GKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTG 264 >4HGN-A nrPDB Length = 176 Score = 27.3 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 34/90 (37%), Gaps = 12/90 (13%) Query: 44 GQRQSPINLQRTKVR---------YNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPST 94 G S IN ++++ + + L+ +G + +G+ +Q+++ Sbjct: 1 GSHMSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIK---DGYAIQLAVKKG 57 Query: 95 MRMTVADGTVYIAQQMHFHWGGASSEISGS 124 + + + G A ++ F G GS Sbjct: 58 LHIAIITGGRTEAVRIRFAALGVKDLYMGS 87 >5YI6-A nrPDB Length = 262 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 6/89 (6%) Query: 127 TVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLA---AFVEVKNYPENTYYSNFISH 183 T+DG + ++I N+++ +A DG + FV N + Sbjct: 74 TIDGKAY---LYISSPNNEFIENFVAGLLEDGKLRVGNVEFFVRKAKILPIPKKFNILKT 130 Query: 184 LANIKYPGQRTTLTGLDVQDMLPRNLQHY 212 ++ I T GL D+LP N + Y Sbjct: 131 ISPIYLKTMIETEDGLKTYDLLPNNSKFY 159 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.133 0.419 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,989,238 Number of Sequences: 36641 Number of extensions: 526823 Number of successful extensions: 1628 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 61 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1286 Number of HSP's gapped (non-prelim): 80 length of query: 308 length of database: 10,336,785 effective HSP length: 97 effective length of query: 211 effective length of database: 6,782,608 effective search space: 1431130288 effective search space used: 1431130288 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)