BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P23258 (451 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1Z5V-A nrPDB 936 0.0 5FM1-C nrPDB 342 2e-94 6E88-B nrPDB 285 2e-77 4FFB-B nrPDB 281 6e-76 5UCY-B nrPDB 277 7e-75 5MLV-I nrPDB 277 8e-75 6GJ4-B nrPDB 276 2e-74 5IJ0-B nrPDB 273 1e-73 2BTQ-B nrPDB 247 8e-66 6E88-A nrPDB 233 1e-61 5MLV-E nrPDB 225 3e-59 5UBQ-C nrPDB 224 6e-59 5W3H-A nrPDB 221 4e-58 2XRP-B nrPDB 220 9e-58 5ND4-A nrPDB 208 5e-54 2BTQ-A nrPDB 198 4e-51 3ZID-A nrPDB 42 6e-04 2B4V-A nrPDB 33 0.35 1JLV-A nrPDB 30 2.4 1CRU-A nrPDB 29 3.4 5CXX-A nrPDB 29 5.3 4XCQ-A nrPDB 28 6.8 3S46-A nrPDB 28 9.3 >1Z5V-A nrPDB Length = 474 Score = 936 bits (2419), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/449 (99%), Positives = 448/449 (99%) Query: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY 60 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPE IVEEFATEGTDRKDVFFYQADDEHY Sbjct: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEAIVEEFATEGTDRKDVFFYQADDEHY 60 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 120 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD Sbjct: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 120 Query: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD Sbjct: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 Query: 181 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 VVVQPYNSLLTLKRLTQNADC+VVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST Sbjct: 181 VVVQPYNSLLTLKRLTQNADCLVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 Query: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP Sbjct: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 Query: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL Sbjct: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 Query: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE Sbjct: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 Query: 421 MDTSREIVQQLIDEYHAATRPDYISWGTQ 449 MDTSREIVQQLIDEYHAATRPDYISWGTQ Sbjct: 421 MDTSREIVQQLIDEYHAATRPDYISWGTQ 449 >5FM1-C nrPDB Length = 473 Score = 342 bits (878), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 181/454 (39%), Positives = 279/454 (61%), Gaps = 18/454 (3%) Query: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVE--EFATEGTDRKDVFFYQADDE 58 M EIITLQ GQCGN +G W QL EH I +G+ + + +TE D FF + Sbjct: 1 MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRN 60 Query: 59 HYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDI 118 + PRA+++D EP VI + N+ + ++P N +++ G AGN+WA+G+ G + +DI Sbjct: 61 KFTPRAIMMDSEPSVIADVENT-FRGFFDPRNTWVASDGASAGNSWANGYDIGTRNQDDI 119 Query: 119 FDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEM 178 + ID+E D +D+ EGF L HS+AGGTGSGLGS LLE L DRYPKK++ TYSVFP + Sbjct: 120 LNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARS-- 177 Query: 179 SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSA 238 S+VVVQ YN++L L+RL +++D VV DN +L I+ N NQL+STI+S+ Sbjct: 178 SEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISS 237 Query: 239 STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD--QSVASVRKTTVLDVMRR 296 T ++R+P YM + + + ++LIP+P LHFL +TP T+D + + + DVM Sbjct: 238 VTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLD 297 Query: 297 LLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASI 356 LL P N +VST + N Y + N I G V+P Q+ +++ ++++R F W +++ Sbjct: 298 LLDPSNSLVSTAMN---NPTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAM 352 Query: 357 QVALSRKSPYL---PSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDM 413 V + R+SPYL P+ + VSG+M++N +++ ++FE C +DK+ + AFL + D+ Sbjct: 353 HVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDL 412 Query: 414 F---KDNFDEMDTSREIVQQLIDEYHAATRPDYI 444 F ++ DE SRE+VQ L+++Y AA + Y+ Sbjct: 413 FQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYL 446 >6E88-B nrPDB Length = 426 Score = 285 bits (730), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 153/439 (34%), Positives = 263/439 (59%), Gaps = 22/439 (5%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P+G + +R DV++ +A++ Y+P Sbjct: 2 REIVHVQAGQCGNQIGSKFWEVISDEHGIQPDGTFKGETDLQLERIDVYYNEANNGKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAVL+DLEP + S+ + P+ +L+ P+N + GAGNNWA G +++G ++ +++ D+ Sbjct: 62 RAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDNVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I +EA+G D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ ++SV P+ ++SD Sbjct: 120 IRKEAEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMSSFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + NP++ +N LVS MS TT Sbjct: 179 VVEPYNATLSVHQLVENTDETYCIDNEALYDICYRTLKLTNPTYGDLNHLVSLTMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N DL L +++P PRLHF M G+ PL+ + + R TV ++ +++ K Sbjct: 239 CLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLSA-KGTQAYRALTVAELTQQMFDAK 297 Query: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 N+M + GR Y+ + + +G + +V + + ++ + + F+ W P +++ Sbjct: 298 NMMAACDPRHGR-------YLTVAAMFRGRMSMREVDEQMLNVQNKNSSYFVEWIPNNVK 350 Query: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 A+ P +++ + N T+I LF+R Q+ + +R+AFL + E M + Sbjct: 351 TAVCDIP---PRGLKMAATFVGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEME 407 Query: 418 FDEMDTSREIVQQLIDEYH 436 F E +++ + LI EY Sbjct: 408 FTEAESN---MNDLISEYQ 423 >4FFB-B nrPDB Length = 463 Score = 281 bits (718), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 156/441 (35%), Positives = 254/441 (57%), Gaps = 11/441 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REII + GQCGNQIG FW+ +C EHG+ G +R +V+F +A ++P Sbjct: 2 REIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 R++ +DLEP I ++ NS L+ P+N + AGN WA G +++G ++ + + D+ Sbjct: 62 RSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQ--SSAGNVWAKGHYTEGAELVDSVMDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I REA+G DSL+GF + HS+ GGTGSG+G+ L+ ++ + +P +++ T+SV P+ + SD Sbjct: 120 IRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSP-KRSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 V+PYN+ L++ +L +++D +DN AL I L + PS+ +N LVS++MS TT Sbjct: 179 RVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LRYPG +N+DL L +L+P PRLHF M GY PLT S S R TV ++ +++ K Sbjct: 239 SLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGS-QSFRSLTVPELTQQMFDAK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + N Y+ + +G+V +V + +++ + F+ W P ++Q A+ Sbjct: 298 NMMAAAD---PRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 + P ++ +AN TSI LF+R Q+ + KR+AFL + E M + F E Sbjct: 355 SVA---PQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEA 411 Query: 422 DTSREIVQQLIDEYHAATRPD 442 +++ + +Y AT D Sbjct: 412 ESNMNDLVSEYQQYQEATVED 432 >5UCY-B nrPDB Length = 429 Score = 277 bits (709), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 152/439 (34%), Positives = 260/439 (59%), Gaps = 22/439 (5%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P Sbjct: 2 REIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ P+ +L+ P+N + G AGNNWA G +++G ++ + + D+ Sbjct: 62 RAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTG--AGNNWAKGHYTEGAELIDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +EA+G D L+GF + HS+ GGTGSG+G+ L+ ++ + YP ++++T+SV P+ ++SD Sbjct: 120 VRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +NAD +V+DN AL I L + P++ +N LVS MS T Sbjct: 179 VVEPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTC 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N+DL L +LIP PRLHF M G+ PLT+ S R TV ++ +++ K Sbjct: 239 CLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGS-QQYRALTVPELTQQMFDAK 297 Query: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 N+M + GR Y+ + +G + +V + + ++ + + F+ W P +I+ Sbjct: 298 NMMCAADPRHGR-------YLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIK 350 Query: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 ++ P +++ + N T+I +F+R Q+ + +R+AFL + E M + Sbjct: 351 SSICDIP---PKGLKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEME 407 Query: 418 FDEMDTSREIVQQLIDEYH 436 F E +++ + L+ EY Sbjct: 408 FTEAESN---MNDLVSEYQ 423 >5MLV-I nrPDB Length = 448 Score = 277 bits (708), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 151/439 (34%), Positives = 259/439 (58%), Gaps = 22/439 (5%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQ+G FW + EHG+ GI + +R +V+F +A Y+P Sbjct: 2 REIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAVL+DLEP + ++ + + L+ P+NI + GAGN WA G +++G ++ + + D+ Sbjct: 62 RAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQ--SGAGNIWAKGHYTEGAELADAVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + REA+ D+L+GF L HS+ GGTGSG+G+ LL ++ + YP +++ T+SV P + SD Sbjct: 120 VRREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAP-APKSSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N+D +DN AL+ I + L I++PS+ +N LVS +M+ TT Sbjct: 179 VVEPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 + R+PG +N+DL L +++P PRLHF M G+ PL S +S + +V ++ +++ Sbjct: 239 SFRFPGELNSDLRKLAVNMVPFPRLHFFMVGFAPLAAIGS-SSFQAVSVPELTQQMFDAN 297 Query: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 N+MV+ GR Y+ + + +G+V +V + ++ ++ + A F+ W P ++ Sbjct: 298 NMMVAADPRHGR-------YLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVL 350 Query: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 A+ P ++S + N TSI +F R Q+ + +R+AFL + E M + Sbjct: 351 KAVCSVPP---KDLKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEME 407 Query: 418 FDEMDTSREIVQQLIDEYH 436 F E +++ + L+ EY Sbjct: 408 FTEAESN---MNDLVSEYQ 423 >6GJ4-B nrPDB Length = 445 Score = 276 bits (705), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 150/439 (34%), Positives = 257/439 (58%), Gaps = 22/439 (5%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P Sbjct: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ + P+ +++ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 62 RAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +E++ D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 120 VRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 179 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N DL L +++P PRLHF M G+ PLT+ S R TV ++ +++ K Sbjct: 239 CLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS-QQYRALTVPELTQQMFDSK 297 Query: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 N+M + GR Y+ + I +G + +V + + ++ + + F+ W P +++ Sbjct: 298 NMMAACDPRHGR-------YLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK 350 Query: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 A+ P ++S + N T+I LF+R Q+ + +R+AFL + E M + Sbjct: 351 TAVCDIP---PRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEME 407 Query: 418 FDEMDTSREIVQQLIDEYH 436 F E +++ + L+ EY Sbjct: 408 FTEAESN---MNDLVSEYQ 423 >5IJ0-B nrPDB Length = 426 Score = 273 bits (698), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 151/439 (34%), Positives = 254/439 (57%), Gaps = 22/439 (5%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R V++ +A Y+P Sbjct: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ + + L+ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +E + D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+PG +N DL L +++P PRLHF M G+ PLT S R TV ++ +++ K Sbjct: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGS-QQYRALTVPELTQQMFDAK 297 Query: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 N+M + GR Y+ + + +G + +V + + I+ + + F+ W P +++ Sbjct: 298 NMMAACDPRHGR-------YLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVK 350 Query: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 VA+ P ++S + N T+I LF+R Q+ + +R+AFL + E M + Sbjct: 351 VAVCDIP---PRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEME 407 Query: 418 FDEMDTSREIVQQLIDEYH 436 F E +++ + L+ EY Sbjct: 408 FTEAESN---MNDLVSEYQ 423 >2BTQ-B nrPDB Length = 426 Score = 247 bits (630), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 158/439 (35%), Positives = 249/439 (56%), Gaps = 16/439 (3%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRK-DVFFYQADDEHYI 61 REI+++ +GQCGNQI FW+ EHG++ G ++E + + +VFF++ D Y+ Sbjct: 2 REILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKEGSNAAANSNMEVFFHKVRDGKYV 61 Query: 62 PRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFS-QGEKIHEDIFD 120 PRAVL+DLEP VI I ++L++ +I GA NNWA G++ +GEK+ + I + Sbjct: 62 PRAVLVDLEPGVIARIEGGDMSQLFDESSIV--RKIPGAANNWARGYNVEGEKVIDQIMN 119 Query: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 +ID + + L+GF++ HSI GG+GSGLGS +LERL YPKK + T+SV P+ +SD Sbjct: 120 VIDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSP-LISD 178 Query: 181 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 V+PYN++LTL+R+ NAD V+LDN AL RIA +L+ ++P++ +N +++ I+S+ T Sbjct: 179 SAVEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLN-RSPNYMDLNNIIALIVSSVT 237 Query: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 +LR+PG +N DL + +L+P P HFL + P+ VR T D+ R Sbjct: 238 ASLRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMRGAGQEGQVR-TNFPDLARETFAQ 296 Query: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 N + D Q Y+A + +G+V V +++ I RK N+ + PAS + L Sbjct: 297 DNFTAAI--DWQQG-VYLAASALFRGDVKAKDVDENMATI--RKSLNYASYMPASGGLKL 351 Query: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 + P SGL + NHT I+++FER Q+D + A+ + + + D Sbjct: 352 G-YAETAPEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSR---DM 407 Query: 421 MDTSREIVQQLIDEYHAAT 439 M +R + L Y A+ Sbjct: 408 MAKARNQIATLAQSYRDAS 426 >6E88-A nrPDB Length = 434 Score = 233 bits (594), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 139/439 (31%), Positives = 240/439 (54%), Gaps = 16/439 (3%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 RE+I++ +GQ G QIG W+ C EHGI P+G + +T + FF Y+P Sbjct: 2 REVISIHVGQAGVQIGNACWELYCLEHGIQPDGTMPTQSTNEGESFTTFFSDTGSGRYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 R++ +DLEP V+ I Y KL++PE + + A NN+A G ++ G+++ + + D Sbjct: 62 RSIFVDLEPTVVDEIRTGTYKKLFHPEQMITGKED--AANNYARGHYTVGKELIDTVLDR 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I R AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 120 IRRLADNCSGLQGFFVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVSTA 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYNS+LT +++DC ++DN A+ I L ++ PS++ +N+++S ++S+ T Sbjct: 179 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDVERPSYTNLNRIISQVVSSITA 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+ G +N DL +L+P PR+HF + YTPL + + A +V D+ +P Sbjct: 239 SLRFDGALNVDLNEFQTNLVPYPRIHFPLAAYTPLISAEK-AYHEALSVSDITNSCFEPA 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N MV Y+A+ + +G+V P V+ ++ I+ ++ F+ W P +V ++ Sbjct: 298 NQMVKCDPRHGK---YMAVCLLYRGDVVPKDVNTAIAAIKTKRTIQFVDWCPTGFKVGIN 354 Query: 362 RKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 + P + ++ + M++N T+I+ + R ++D + + AF+ + E M + Sbjct: 355 YQPPTVVPGGDLAKVPRAVCMLSNTTAIAEAWSRLDYKFDLMYAKRAFVHWYVGEGMEEG 414 Query: 417 NFDEMDTSREIVQQLIDEY 435 F E +RE + L +Y Sbjct: 415 EFTE---AREDLAALEKDY 430 >5MLV-E nrPDB Length = 455 Score = 225 bits (573), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 147/453 (32%), Positives = 244/453 (53%), Gaps = 38/453 (8%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGT----------DRKDVFF 52 RE+I++ +GQ G QIG W+ C EHGI P+G F TE + D FF Sbjct: 2 REVISVHVGQAGVQIGNACWELYCLEHGIGPDG----FPTENSEVHKNNSYLNDGFGTFF 57 Query: 53 YQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQG 111 + ++PR++ +DLEP VI + PY L++PE + + A NN+A G ++ G Sbjct: 58 SETGQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKED--ASNNYARGHYTVG 115 Query: 112 EKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSV 171 +++ + + + I R AD L+GF++ HS GGTGSGLG+ LLERLN Y KK +SV Sbjct: 116 KEMIDSVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSV 175 Query: 172 FPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQL 231 +P ++S VV+PYNS+LT N+DC ++DN A I L I+ P++ +N+L Sbjct: 176 YP-APQVSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRL 234 Query: 232 VSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVL 291 ++ ++S+ T +LR+ G +N DL +L+P PR+HF + Y+P+ + + A +V Sbjct: 235 IAQVVSSITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVS-AAKAFHESNSVQ 293 Query: 292 DVMRRLLQPKNVMVS----TGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLAN 347 ++ + +P N MV TGR Y+A + +G+V P V ++ I+ R+ Sbjct: 294 EITNQCFEPYNQMVKCDPRTGR-------YMATCLLYRGDVIPRDVQAAVTSIKSRRTIQ 346 Query: 348 FIPWGPASIQVALSRKSP-YLPSAHRV----SGLMMANHTSISSLFERTCRQYDKLRKRE 402 F+ W P ++ + + P ++P + + M++N TSI+ + R ++D + + Sbjct: 347 FVDWCPTGFKIGICYEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKR 406 Query: 403 AFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEY 435 AF+ + E M + F E +RE + L +Y Sbjct: 407 AFVHWYVGEGMEEGEFSE---AREDLAALERDY 436 >5UBQ-C nrPDB Length = 441 Score = 224 bits (571), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 141/441 (31%), Positives = 247/441 (56%), Gaps = 18/441 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60 RE+I++ +GQ G Q+G W+ C EHGI P+G + T G D + FF + + Sbjct: 2 REVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKH 61 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF 119 +PRAV LDLEP VI + Y +L++PE + + A NN+A G ++ G++I + Sbjct: 62 VPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKED--AANNFARGHYTIGKEIVDLCL 119 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 D I + AD L+GF++ +S+ GGTGSGLGS LLERL+ Y KK ++++P+ ++S Sbjct: 120 DRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSP-QVS 178 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV+PYNS+L+ L ++ D V+LDN A+ I L I+ P+++ +N+L++ ++S+ Sbjct: 179 TAVVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSL 238 Query: 240 TTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQ 299 T +LR+ G +N D+ +L+P PR+HF+++ Y P+ + + A + +V ++ + Sbjct: 239 TASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEK-AYHEQLSVAEITNSAFE 297 Query: 300 PKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA 359 P N+M Y+A + +G+V P V+ S+ I+ ++ F+ W P +V Sbjct: 298 PANMMAKCDPRHGK---YMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVG 354 Query: 360 LSRKSPYLPSAHRVSGLMMA-----NHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMF 414 ++ + P + ++ +M A N T+I+ +F R ++D + + AF+ + E M Sbjct: 355 INYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGME 414 Query: 415 KDNFDEMDTSREIVQQLIDEY 435 + F E +RE + L +Y Sbjct: 415 EGEFSE---AREDLAALEKDY 432 >5W3H-A nrPDB Length = 447 Score = 221 bits (564), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 148/456 (32%), Positives = 252/456 (55%), Gaps = 29/456 (6%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATE---GTDRKDVFFYQADDEH 59 RE+I++ +GQ G QIG W+ EHGI P+G +E+ ++ G + FF++ Sbjct: 2 REVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGK 61 Query: 60 YIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDI 118 ++PRA+ +DLEP VI + N PY L++PE + + A NN+A G ++ G +I D+ Sbjct: 62 FVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKED--AANNYARGHYTVGREILGDV 119 Query: 119 FDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEM 178 D I + AD D L+GF+ HS+ GGTGSGLGS LLE L+ Y KK ++V+P ++ Sbjct: 120 LDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYP-APQV 178 Query: 179 SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSA 238 S VV+PYN++LT ++ADC ++DN A+ + L I PSF+ +N L++ ++S+ Sbjct: 179 STSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSS 238 Query: 239 STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLL 298 T +LR+ G +N DL +L+P PR+HF + Y+P+ + +S A +V ++ Sbjct: 239 VTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLS-KSKAFHESNSVSEITNACF 297 Query: 299 QPKNVMVSTG-RDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 +P N MV RD + Y+A + +G+V V +++++++ +K + W P + Sbjct: 298 EPGNQMVKCDPRDGK----YMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFK 353 Query: 358 VALSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKED 412 + + + P +++ + M++N TSI+ ++R R++D + + AF+ + E Sbjct: 354 IGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEG 413 Query: 413 MFKDNFDEMDTSREIVQQLIDEYHAATRPDYISWGT 448 M + F E +RE + AA DYI G Sbjct: 414 MEEGEFTE---AREDL--------AALERDYIEVGA 438 >2XRP-B nrPDB Length = 452 Score = 220 bits (561), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 139/441 (31%), Positives = 238/441 (53%), Gaps = 18/441 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60 RE I++ +GQ G QIG W+ C EHGI P+G + T G D + FF + + Sbjct: 2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKH 61 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF 119 +PRAV +DLEP VI + Y +L++PE + + A NN+A G ++ G++I + + Sbjct: 62 VPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKED--AANNYARGHYTIGKEIIDLVL 119 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 D I + AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 120 DRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVS 178 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV+PYNS+LT +++DC ++DN A+ I L I+ P+++ +N+L+ I+S+ Sbjct: 179 TAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSI 238 Query: 240 TTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQ 299 T +LR+ G +N DL +L+P PR HF + Y P+ + + A + +V ++ + Sbjct: 239 TASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEK-AYHEQLSVAEITNACFE 297 Query: 300 PKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA 359 P N MV Y+A + +G+V P V+ ++ I+ ++ F+ W P +V Sbjct: 298 PANQMVKCDPRHGK---YMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVG 354 Query: 360 LSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMF 414 ++ + P + ++ + M++N T+I+ + R ++D + + AF+ + E M Sbjct: 355 INYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGME 414 Query: 415 KDNFDEMDTSREIVQQLIDEY 435 + F E +RE + L +Y Sbjct: 415 EGEFSE---AREDMAALEKDY 432 >5ND4-A nrPDB Length = 412 Score = 208 bits (529), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 134/439 (30%), Positives = 230/439 (52%), Gaps = 40/439 (9%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 RE I++ +GQ G QIG W+ C EHGI P+G ++P Sbjct: 1 RECISIHVGQAGVQIGNACWELYCLEHGIQPDG------------------------HVP 36 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAV +DLEP VI + Y +L++PE + + A NN+A G ++ G++I + + D Sbjct: 37 RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKED--AANNYARGHYTIGKEIIDLVLDR 94 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I + AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 95 IRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVSTA 153 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYNS+LT +++DC ++DN A+ I L I+ P+++ +N+L+ I+S+ T Sbjct: 154 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 213 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+ G +N DL +L+P PR HF + Y P+ + + A + +V ++ +P Sbjct: 214 SLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEK-AYHEQLSVAEITNACFEPA 272 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N MV Y+A + +G+V P V+ ++ I+ ++ F+ W P +V ++ Sbjct: 273 NQMVKCDPRHGK---YMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGIN 329 Query: 362 RKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 + P + ++ + M++N T+I+ + R ++D + + AF+ + E M + Sbjct: 330 YEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEG 389 Query: 417 NFDEMDTSREIVQQLIDEY 435 F E +RE + L +Y Sbjct: 390 EFSE---AREDMAALEKDY 405 >2BTQ-A nrPDB Length = 473 Score = 198 bits (504), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 136/446 (30%), Positives = 240/446 (53%), Gaps = 35/446 (7%) Query: 6 ITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKD--VFFY---QADDEHY 60 I + +GQ GNQI FWK +C EHGI P + + A R + FF ++ Y Sbjct: 7 IVVSIGQAGNQIAASFWKTVCLEHGIDP--LTGQTAPGVAPRGNWSSFFSKLGESSSGSY 64 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGF-SQGEKIHEDIF 119 +PRA+++DLEP VI ++ + L+NP N L GAG N+A G+ G ++ ++ Sbjct: 65 VPRAIMVDLEPSVIDNV-KATSGSLFNPAN--LISRTEGAGGNFAVGYLGAGREVLPEVM 121 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 +D E D D++ G ++ H+I GGTGSG G+ L+E L ++Y + V + +V P+ ++S Sbjct: 122 SRLDYEIDKCDNVGGIIVLHAIGGGTGSGFGALLIESLKEKYGEIPVLSCAVLPSP-QVS 180 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV +PYN++ L L ++AD ++ DN AL +A + +I++P+ +N L++ ++ Sbjct: 181 SVVTEPYNTVFALNTLRRSADACLIFDNEALFDLAHRKWNIESPTVDDLNLLITEALAGI 240 Query: 240 TTTLRYPGYMNND--LIGLIASLIPTPRLHFLMTGYTPLT-TDQSVASVRKTTVLDVMRR 296 T ++R+ G++ + L L+ +L+P P LHFLM + PLT D+S + + ++++ Sbjct: 241 TASMRFSGFLTVEISLRELLTNLVPQPSLHFLMCAFAPLTPPDRS--KFEELGIEEMIKS 298 Query: 297 LLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWG 352 L +V + GR T Y I+ D +L +RE+ + W Sbjct: 299 LFDNGSVFAACSPMEGRFLSTAVLYRGIME------DKPLADAALAAMREKLPLTY--WI 350 Query: 353 PASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKED 412 P + ++ + P + +HR S +++AN+T I+ + +R C +DKL +R+AF + E Sbjct: 351 PTAFKIGYVEQ-PGI--SHRKSMVLLANNTEIARVLDRICHNFDKLWQRKAFANWYLNEG 407 Query: 413 MFKDNFDEMDTSREIVQQLIDEYHAA 438 M + ++++ R Q+L+ Y A Sbjct: 408 MSE---EQINVLRASAQELVQSYQVA 430 >3ZID-A nrPDB Length = 373 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 32/136 (23%), Positives = 63/136 (46%), Gaps = 12/136 (8%) Query: 99 GAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLN 158 G G N + G + E I + I++ D + + S++GGTGS ++ L Sbjct: 74 GVGANRSKGKQGFWENQEMILEEIEKRGD----FDLIFVMTSVSGGTGSSFSPLMIHELK 129 Query: 159 DRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQ-NADCVVVLDNTALNRIATDR 217 RY + +V P ++E + + N+ L+ + + AD ++++DN L R + D Sbjct: 130 KRYKNATIVPIAVLPFREEGT---IYLQNAAFCLREMIEVEADGMILVDNQYLKRFSGD- 185 Query: 218 LHIQNPSFSQINQLVS 233 ++ +IN +V+ Sbjct: 186 ---IASAYDRINTMVA 198 >2B4V-A nrPDB Length = 468 Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 20/99 (20%) Query: 240 TTTLRY-PGYMNNDLIGLIASLIPTPRLHF------LMTGYTPLTTDQSVASVRKTTVLD 292 T RY P Y+ N+L+GL + P +L F YTPL+ ++ + +T +LD Sbjct: 104 TVIKRYVPHYLRNNLLGLTEARTPVVKLRFANDEKVARARYTPLSEEEDRKA--RTALLD 161 Query: 293 VMRRLLQPKNVMV---STGR--------DRQTNHCYIAI 320 V + + +V GR DR T C IAI Sbjct: 162 VRNQCVGDNDVEYIAEKMGRDNVEGIRVDRTTYGCRIAI 200 >1JLV-A nrPDB Length = 209 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 25/42 (59%) Query: 369 SAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRK 410 S + V+G +A + +++ +ERT ++ EA +E+FRK Sbjct: 164 STYDVAGFELAKYPHVAAWYERTRKEAPGAAINEAGIEEFRK 205 >1CRU-A nrPDB Length = 454 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPEN-IYLSEHGGGA--GNNWASGFSQGEKIHEDIF 119 +A + + +VI S LN P+A L+ P+N I+L+E G N SG + +F Sbjct: 11 KAKSENFDKKVILSNLNKPHALLWGPDNQIWLTERATGKILRVNPESGSVK------TVF 64 Query: 120 DI--IDREADGSDSLEGFVL 137 + I +ADG + L GF Sbjct: 65 QVPEIVNDADGQNGLLGFAF 84 >5CXX-A nrPDB Length = 275 Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 16/31 (51%) Query: 236 MSASTTTLRYPGYMNNDLIGLIASLIPTPRL 266 S T Y GYM +DLIG + + P P + Sbjct: 155 FSMGARTSLYIGYMRSDLIGYVGAFAPAPGI 185 >4XCQ-A nrPDB Length = 318 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 21/47 (44%) Query: 131 SLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDE 177 S + + ++AGGTGSG+ +L YP K V P E Sbjct: 88 SCDIVIFVATMAGGTGSGITPPILGLAKQMYPNKHFGFVGVLPKATE 134 >3S46-A nrPDB Length = 367 Score = 28.1 bits (61), Expect = 9.3, Method: Compositional matrix adjust. Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 14/95 (14%) Query: 6 ITLQLGQCGNQIGF------EFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEH 59 + L++ +IGF E + L +HG+ EGI FAT + D ++ A E Sbjct: 126 VHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVEGIFTHFATADEESDD--YFNAQLER 183 Query: 60 YIPRAVLLDLE--PRVIHSILNSPYAKLYNPENIY 92 + + +L ++ P ++H+ ++ L++ E I+ Sbjct: 184 F--KTILASMKEVPELVHA--SNSATTLWHVETIF 214 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1Z5V-A nrPDB 658 0.0 6GJ4-B nrPDB 622 e-178 5UCY-B nrPDB 615 e-177 5IJ0-B nrPDB 614 e-176 6E88-B nrPDB 613 e-176 2XRP-B nrPDB 601 e-172 6E88-A nrPDB 600 e-172 4FFB-B nrPDB 585 e-167 5UBQ-C nrPDB 583 e-167 5MLV-I nrPDB 577 e-165 5MLV-E nrPDB 573 e-164 5W3H-A nrPDB 572 e-163 5ND4-A nrPDB 563 e-161 5FM1-C nrPDB 504 e-143 2BTQ-B nrPDB 477 e-135 2BTQ-A nrPDB 456 e-129 3ZID-A nrPDB 143 2e-34 Sequences not found previously or not previously below threshold: 4XCQ-A nrPDB 44 1e-04 3V3T-A nrPDB 42 8e-04 2R6R-1 nrPDB 39 0.005 4B46-A nrPDB 38 0.011 2CH6-A nrPDB 37 0.017 4B45-A nrPDB 37 0.018 6G58-A nrPDB 37 0.022 1OFU-A nrPDB 35 0.066 2VAW-A nrPDB 35 0.075 5T6E-A nrPDB 35 0.084 4XD9-B nrPDB 32 0.43 6GI9-A nrPDB 31 1.2 2VAP-A nrPDB 30 2.2 1QF6-A nrPDB 30 2.2 1BWR-A nrPDB 30 2.3 4EI8-A nrPDB 30 2.6 >1Z5V-A nrPDB Length = 474 Score = 658 bits (1698), Expect = 0.0, Method: Composition-based stats. Identities = 447/449 (99%), Positives = 448/449 (99%) Query: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY 60 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPE IVEEFATEGTDRKDVFFYQADDEHY Sbjct: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEAIVEEFATEGTDRKDVFFYQADDEHY 60 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 120 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD Sbjct: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 120 Query: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD Sbjct: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 Query: 181 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 VVVQPYNSLLTLKRLTQNADC+VVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST Sbjct: 181 VVVQPYNSLLTLKRLTQNADCLVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 Query: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP Sbjct: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 Query: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL Sbjct: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 Query: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE Sbjct: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 Query: 421 MDTSREIVQQLIDEYHAATRPDYISWGTQ 449 MDTSREIVQQLIDEYHAATRPDYISWGTQ Sbjct: 421 MDTSREIVQQLIDEYHAATRPDYISWGTQ 449 >6GJ4-B nrPDB Length = 445 Score = 622 bits (1603), Expect = e-178, Method: Composition-based stats. Identities = 148/438 (33%), Positives = 255/438 (58%), Gaps = 11/438 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P Sbjct: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ + P+ +++ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 62 RAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +E++ D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 120 VRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 179 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N DL L +++P PRLHF M G+ PLT+ S R TV ++ +++ K Sbjct: 239 CLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS-QQYRALTVPELTQQMFDSK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + Y+ + I +G + +V + + ++ + + F+ W P +++ A+ Sbjct: 298 NMMAACDPRHGR---YLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 P ++S + N T+I LF+R Q+ + +R+AFL + E M + F E Sbjct: 355 DIPP---RGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEA 411 Query: 422 DTSREIVQQLIDEYHAAT 439 +++ + +Y AT Sbjct: 412 ESNMNDLVSEYQQYQDAT 429 >5UCY-B nrPDB Length = 429 Score = 615 bits (1587), Expect = e-177, Method: Composition-based stats. Identities = 150/438 (34%), Positives = 258/438 (58%), Gaps = 11/438 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P Sbjct: 2 REIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ P+ +L+ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 62 RAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQ--TGAGNNWAKGHYTEGAELIDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +EA+G D L+GF + HS+ GGTGSG+G+ L+ ++ + YP ++++T+SV P+ ++SD Sbjct: 120 VRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +NAD +V+DN AL I L + P++ +N LVS MS T Sbjct: 179 VVEPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTC 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N+DL L +LIP PRLHF M G+ PLT+ S R TV ++ +++ K Sbjct: 239 CLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGS-QQYRALTVPELTQQMFDAK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + Y+ + +G + +V + + ++ + + F+ W P +I+ ++ Sbjct: 298 NMMCAADPRHGR---YLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSIC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 P +++ + N T+I +F+R Q+ + +R+AFL + E M + F E Sbjct: 355 DIPP---KGLKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEA 411 Query: 422 DTSREIVQQLIDEYHAAT 439 +++ + +Y AT Sbjct: 412 ESNMNDLVSEYQQYQDAT 429 >5IJ0-B nrPDB Length = 426 Score = 614 bits (1583), Expect = e-176, Method: Composition-based stats. Identities = 147/435 (33%), Positives = 250/435 (57%), Gaps = 11/435 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R V++ +A Y+P Sbjct: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RA+L+DLEP + S+ + + L+ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + +E + D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+PG +N DL L +++P PRLHF M G+ PLT S R TV ++ +++ K Sbjct: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGS-QQYRALTVPELTQQMFDAK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + Y+ + + +G + +V + + I+ + + F+ W P +++VA+ Sbjct: 298 NMMAACDPRHGR---YLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 P ++S + N T+I LF+R Q+ + +R+AFL + E M + F E Sbjct: 355 DIPP---RGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEA 411 Query: 422 DTSREIVQQLIDEYH 436 +++ + +Y Sbjct: 412 ESNMNDLVSEYQQYQ 426 >6E88-B nrPDB Length = 426 Score = 613 bits (1580), Expect = e-176, Method: Composition-based stats. Identities = 148/435 (34%), Positives = 259/435 (59%), Gaps = 11/435 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQIG +FW+ + EHGI P+G + +R DV++ +A++ Y+P Sbjct: 2 REIVHVQAGQCGNQIGSKFWEVISDEHGIQPDGTFKGETDLQLERIDVYYNEANNGKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAVL+DLEP + S+ + P+ +L+ P+N + GAGNNWA G +++G ++ +++ D+ Sbjct: 62 RAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDNVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I +EA+G D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ ++SV P+ ++SD Sbjct: 120 IRKEAEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMSSFSVVPSP-KVSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N D +DN AL I L + NP++ +N LVS MS TT Sbjct: 179 VVEPYNATLSVHQLVENTDETYCIDNEALYDICYRTLKLTNPTYGDLNHLVSLTMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 LR+PG +N DL L +++P PRLHF M G+ PL + + + R TV ++ +++ K Sbjct: 239 CLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL-SAKGTQAYRALTVAELTQQMFDAK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + Y+ + + +G + +V + + ++ + + F+ W P +++ A+ Sbjct: 298 NMMAACDPRHGR---YLTVAAMFRGRMSMREVDEQMLNVQNKNSSYFVEWIPNNVKTAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 P +++ + N T+I LF+R Q+ + +R+AFL + E M + F E Sbjct: 355 DIPP---RGLKMAATFVGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEA 411 Query: 422 DTSREIVQQLIDEYH 436 +++ + +Y Sbjct: 412 ESNMNDLISEYQQYQ 426 >2XRP-B nrPDB Length = 452 Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats. Identities = 139/448 (31%), Positives = 238/448 (53%), Gaps = 18/448 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60 RE I++ +GQ G QIG W+ C EHGI P+G + T G D + FF + + Sbjct: 2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKH 61 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF 119 +PRAV +DLEP VI + Y +L++PE + + A NN+A G ++ G++I + + Sbjct: 62 VPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKED--AANNYARGHYTIGKEIIDLVL 119 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 D I + AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 120 DRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAP-QVS 178 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV+PYNS+LT +++DC ++DN A+ I L I+ P+++ +N+L+ I+S+ Sbjct: 179 TAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSI 238 Query: 240 TTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQ 299 T +LR+ G +N DL +L+P PR HF + Y P+ + + A + +V ++ + Sbjct: 239 TASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEK-AYHEQLSVAEITNACFE 297 Query: 300 PKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA 359 P N MV Y+A + +G+V P V+ ++ I+ ++ F+ W P +V Sbjct: 298 PANQMVKCDPRHGK---YMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVG 354 Query: 360 LSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMF 414 ++ + P + ++ + M++N T+I+ + R ++D + + AF+ + E M Sbjct: 355 INYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGME 414 Query: 415 KDNFDEMDTSREIVQQLIDEYHAATRPD 442 + F E +RE + L +Y Sbjct: 415 EGEFSE---AREDMAALEKDYEEVGVDS 439 >6E88-A nrPDB Length = 434 Score = 600 bits (1547), Expect = e-172, Method: Composition-based stats. Identities = 139/441 (31%), Positives = 240/441 (54%), Gaps = 16/441 (3%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 RE+I++ +GQ G QIG W+ C EHGI P+G + +T + FF Y+P Sbjct: 2 REVISIHVGQAGVQIGNACWELYCLEHGIQPDGTMPTQSTNEGESFTTFFSDTGSGRYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 R++ +DLEP V+ I Y KL++PE + + A NN+A G ++ G+++ + + D Sbjct: 62 RSIFVDLEPTVVDEIRTGTYKKLFHPEQMITGKED--AANNYARGHYTVGKELIDTVLDR 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I R AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 120 IRRLADNCSGLQGFFVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAP-QVSTA 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYNS+LT +++DC ++DN A+ I L ++ PS++ +N+++S ++S+ T Sbjct: 179 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDVERPSYTNLNRIISQVVSSITA 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+ G +N DL +L+P PR+HF + YTPL + + A +V D+ +P Sbjct: 239 SLRFDGALNVDLNEFQTNLVPYPRIHFPLAAYTPLISAEK-AYHEALSVSDITNSCFEPA 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N MV Y+A+ + +G+V P V+ ++ I+ ++ F+ W P +V ++ Sbjct: 298 NQMVKCDPRHGK---YMAVCLLYRGDVVPKDVNTAIAAIKTKRTIQFVDWCPTGFKVGIN 354 Query: 362 RKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 + P + ++ + M++N T+I+ + R ++D + + AF+ + E M + Sbjct: 355 YQPPTVVPGGDLAKVPRAVCMLSNTTAIAEAWSRLDYKFDLMYAKRAFVHWYVGEGMEEG 414 Query: 417 NFDEMDTSREIVQQLIDEYHA 437 F E +RE + L +Y Sbjct: 415 EFTE---AREDLAALEKDYEE 432 >4FFB-B nrPDB Length = 463 Score = 585 bits (1507), Expect = e-167, Method: Composition-based stats. Identities = 156/441 (35%), Positives = 254/441 (57%), Gaps = 11/441 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REII + GQCGNQIG FW+ +C EHG+ G +R +V+F +A ++P Sbjct: 2 REIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 R++ +DLEP I ++ NS L+ P+N + AGN WA G +++G ++ + + D+ Sbjct: 62 RSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQ--SSAGNVWAKGHYTEGAELVDSVMDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I REA+G DSL+GF + HS+ GGTGSG+G+ L+ ++ + +P +++ T+SV P+ + SD Sbjct: 120 IRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSP-KRSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 V+PYN+ L++ +L +++D +DN AL I L + PS+ +N LVS++MS TT Sbjct: 179 RVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LRYPG +N+DL L +L+P PRLHF M GY PLT S S R TV ++ +++ K Sbjct: 239 SLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGS-QSFRSLTVPELTQQMFDAK 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+M + N Y+ + +G+V +V + +++ + F+ W P ++Q A+ Sbjct: 298 NMMAAADPR---NGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 +P ++ +AN TSI LF+R Q+ + KR+AFL + E M + F E Sbjct: 355 SVAP---QGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEA 411 Query: 422 DTSREIVQQLIDEYHAATRPD 442 +++ + +Y AT D Sbjct: 412 ESNMNDLVSEYQQYQEATVED 432 >5UBQ-C nrPDB Length = 441 Score = 583 bits (1504), Expect = e-167, Method: Composition-based stats. Identities = 140/443 (31%), Positives = 248/443 (55%), Gaps = 18/443 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60 RE+I++ +GQ G Q+G W+ C EHGI P+G + T G D + FF + + Sbjct: 2 REVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKH 61 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF 119 +PRAV LDLEP VI + Y +L++PE + + A NN+A G ++ G++I + Sbjct: 62 VPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKED--AANNFARGHYTIGKEIVDLCL 119 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 D I + AD L+GF++ +S+ GGTGSGLGS LLERL+ Y KK ++++P+ ++S Sbjct: 120 DRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSP-QVS 178 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV+PYNS+L+ L ++ D V+LDN A+ I L I+ P+++ +N+L++ ++S+ Sbjct: 179 TAVVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSL 238 Query: 240 TTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQ 299 T +LR+ G +N D+ +L+P PR+HF+++ Y P+ + + A + +V ++ + Sbjct: 239 TASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEK-AYHEQLSVAEITNSAFE 297 Query: 300 PKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA 359 P N+M Y+A + +G+V P V+ S+ I+ ++ F+ W P +V Sbjct: 298 PANMMAKCDPRHGK---YMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVG 354 Query: 360 LSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMF 414 ++ + P + ++ + M++N T+I+ +F R ++D + + AF+ + E M Sbjct: 355 INYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGME 414 Query: 415 KDNFDEMDTSREIVQQLIDEYHA 437 + F E +RE + L +Y Sbjct: 415 EGEFSE---AREDLAALEKDYEE 434 >5MLV-I nrPDB Length = 448 Score = 577 bits (1486), Expect = e-165, Method: Composition-based stats. Identities = 148/437 (33%), Positives = 256/437 (58%), Gaps = 11/437 (2%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 REI+ +Q GQCGNQ+G FW + EHG+ GI + +R +V+F +A Y+P Sbjct: 2 REIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYVP 61 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAVL+DLEP + ++ + + L+ P+NI + GAGN WA G +++G ++ + + D+ Sbjct: 62 RAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQ--SGAGNIWAKGHYTEGAELADAVLDV 119 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 + REA+ D+L+GF L HS+ GGTGSG+G+ LL ++ + YP +++ T+SV P + SD Sbjct: 120 VRREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAPAP-KSSDT 178 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYN+ L++ +L +N+D +DN AL+ I + L I++PS+ +N LVS +M+ TT Sbjct: 179 VVEPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTT 238 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 + R+PG +N+DL L +++P PRLHF M G+ PL S +S + +V ++ +++ Sbjct: 239 SFRFPGELNSDLRKLAVNMVPFPRLHFFMVGFAPLAAIGS-SSFQAVSVPELTQQMFDAN 297 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N+MV+ Y+ + + +G+V +V + ++ ++ + A F+ W P ++ A+ Sbjct: 298 NMMVAADPRHGR---YLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVLKAVC 354 Query: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 P ++S + N TSI +F R Q+ + +R+AFL + E M + F E Sbjct: 355 SVPP---KDLKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEMEFTEA 411 Query: 422 DTSREIVQQLIDEYHAA 438 +++ + +Y A Sbjct: 412 ESNMNDLVSEYQQYQEA 428 >5MLV-E nrPDB Length = 455 Score = 573 bits (1477), Expect = e-164, Method: Composition-based stats. Identities = 141/452 (31%), Positives = 238/452 (52%), Gaps = 22/452 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGT------DRKDVFFYQAD 56 RE+I++ +GQ G QIG W+ C EHGI P+G E + D FF + Sbjct: 2 REVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTENSEVHKNNSYLNDGFGTFFSETG 61 Query: 57 DEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIH 115 ++PR++ +DLEP VI + PY L++PE + + A NN+A G ++ G+++ Sbjct: 62 QGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKED--ASNNYARGHYTVGKEMI 119 Query: 116 EDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQ 175 + + + I R AD L+GF++ HS GGTGSGLG+ LLERLN Y KK +SV+P Sbjct: 120 DSVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAP 179 Query: 176 DEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTI 235 ++S VV+PYNS+LT N+DC ++DN A I L I+ P++ +N+L++ + Sbjct: 180 -QVSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQV 238 Query: 236 MSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMR 295 +S+ T +LR+ G +N DL +L+P PR+HF + Y+P+ + + A +V ++ Sbjct: 239 VSSITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSA-AKAFHESNSVQEITN 297 Query: 296 RLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPAS 355 + +P N MV Y+A + +G+V P V ++ I+ R+ F+ W P Sbjct: 298 QCFEPYNQMVKCDPRTGR---YMATCLLYRGDVIPRDVQAAVTSIKSRRTIQFVDWCPTG 354 Query: 356 IQVALSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRK 410 ++ + + P ++ + M++N TSI+ + R ++D + + AF+ + Sbjct: 355 FKIGICYEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVG 414 Query: 411 EDMFKDNFDEMDTSREIVQQLIDEYHAATRPD 442 E M + F E +RE + L +Y + Sbjct: 415 EGMEEGEFSE---AREDLAALERDYEEVGQDS 443 >5W3H-A nrPDB Length = 447 Score = 572 bits (1474), Expect = e-163, Method: Composition-based stats. Identities = 143/452 (31%), Positives = 245/452 (54%), Gaps = 19/452 (4%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEF---ATEGTDRKDVFFYQADDEH 59 RE+I++ +GQ G QIG W+ EHGI P+G +E+ G + FF++ Sbjct: 2 REVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGK 61 Query: 60 YIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDI 118 ++PRA+ +DLEP VI + N PY L++PE + + A NN+A G ++ G +I D+ Sbjct: 62 FVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKED--AANNYARGHYTVGREILGDV 119 Query: 119 FDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEM 178 D I + AD D L+GF+ HS+ GGTGSGLGS LLE L+ Y KK ++V+P ++ Sbjct: 120 LDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAP-QV 178 Query: 179 SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSA 238 S VV+PYN++LT ++ADC ++DN A+ + L I PSF+ +N L++ ++S+ Sbjct: 179 STSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSS 238 Query: 239 STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLL 298 T +LR+ G +N DL +L+P PR+HF + Y+P+ + +S A +V ++ Sbjct: 239 VTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLS-KSKAFHESNSVSEITNACF 297 Query: 299 QPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQV 358 +P N MV Y+A + +G+V V +++++++ +K + W P ++ Sbjct: 298 EPGNQMVKCDPRDGK---YMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKI 354 Query: 359 ALSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDM 413 + + P +++ + M++N TSI+ ++R R++D + + AF+ + E M Sbjct: 355 GICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGM 414 Query: 414 FKDNFDEMDTSREIVQQLIDEYHAATRPDYIS 445 + F E +RE + L +Y Y Sbjct: 415 EEGEFTE---AREDLAALERDYIEVGADSYAE 443 >5ND4-A nrPDB Length = 412 Score = 563 bits (1452), Expect = e-161, Method: Composition-based stats. Identities = 134/446 (30%), Positives = 230/446 (51%), Gaps = 40/446 (8%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62 RE I++ +GQ G QIG W+ C EHGI P+G ++P Sbjct: 1 RECISIHVGQAGVQIGNACWELYCLEHGIQPDG------------------------HVP 36 Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 RAV +DLEP VI + Y +L++PE + + A NN+A G ++ G++I + + D Sbjct: 37 RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKED--AANNYARGHYTIGKEIIDLVLDR 94 Query: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 I + AD L+GF + HS GGTGSG S L+ERL+ Y KK +S++P ++S Sbjct: 95 IRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAP-QVSTA 153 Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 VV+PYNS+LT +++DC ++DN A+ I L I+ P+++ +N+L+ I+S+ T Sbjct: 154 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 213 Query: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 +LR+ G +N DL +L+P PR HF + Y P+ + + A + +V ++ +P Sbjct: 214 SLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEK-AYHEQLSVAEITNACFEPA 272 Query: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 N MV Y+A + +G+V P V+ ++ I+ ++ F+ W P +V ++ Sbjct: 273 NQMVKCDPRHGK---YMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGIN 329 Query: 362 RKSPYLPSAHRVSGL-----MMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 + P + ++ + M++N T+I+ + R ++D + + AF+ + E M + Sbjct: 330 YEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEG 389 Query: 417 NFDEMDTSREIVQQLIDEYHAATRPD 442 F E +RE + L +Y Sbjct: 390 EFSE---AREDMAALEKDYEEVGVDS 412 >5FM1-C nrPDB Length = 473 Score = 504 bits (1298), Expect = e-143, Method: Composition-based stats. Identities = 181/455 (39%), Positives = 278/455 (61%), Gaps = 18/455 (3%) Query: 1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGI--VEEFATEGTDRKDVFFYQADDE 58 M EIITLQ GQCGN +G W QL EH I +G+ + + +TE D FF + Sbjct: 1 MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRN 60 Query: 59 HYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDI 118 + PRA+++D EP VI + N + ++P N +++ G AGN+WA+G+ G + +DI Sbjct: 61 KFTPRAIMMDSEPSVIADVEN-TFRGFFDPRNTWVASDGASAGNSWANGYDIGTRNQDDI 119 Query: 119 FDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEM 178 + ID+E D +D+ EGF L HS+AGGTGSGLGS LLE L DRYPKK++ TYSVFP + Sbjct: 120 LNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARS-- 177 Query: 179 SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSA 238 S+VVVQ YN++L L+RL +++D VV DN +L I+ N NQL+STI+S+ Sbjct: 178 SEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISS 237 Query: 239 STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD--QSVASVRKTTVLDVMRR 296 T ++R+P YM + + + ++LIP+P LHFL +TP T+D + + + DVM Sbjct: 238 VTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLD 297 Query: 297 LLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASI 356 LL P N +VST + N Y + N I G V+P Q+ +++ ++++R F W +++ Sbjct: 298 LLDPSNSLVSTAMN---NPTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAM 352 Query: 357 QVALSRKSPYL---PSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDM 413 V + R+SPYL P+ + VSG+M++N +++ ++FE C +DK+ + AFL + D+ Sbjct: 353 HVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDL 412 Query: 414 F---KDNFDEMDTSREIVQQLIDEYHAATRPDYIS 445 F ++ DE SRE+VQ L+++Y AA + Y+ Sbjct: 413 FQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYLD 447 >2BTQ-B nrPDB Length = 426 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 156/439 (35%), Positives = 247/439 (56%), Gaps = 16/439 (3%) Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRK-DVFFYQADDEHYI 61 REI+++ +GQCGNQI FW+ EHG++ G ++E + + +VFF++ D Y+ Sbjct: 2 REILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKEGSNAAANSNMEVFFHKVRDGKYV 61 Query: 62 PRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFS-QGEKIHEDIFD 120 PRAVL+DLEP VI I ++L++ +I GA NNWA G++ +GEK+ + I + Sbjct: 62 PRAVLVDLEPGVIARIEGGDMSQLFDESSIV--RKIPGAANNWARGYNVEGEKVIDQIMN 119 Query: 121 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 180 +ID + + L+GF++ HSI GG+GSGLGS +LERL YPKK + T+SV P+ +SD Sbjct: 120 VIDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSP-LISD 178 Query: 181 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 240 V+PYN++LTL+R+ NAD V+LDN AL RIA +L+ ++P++ +N +++ I+S+ T Sbjct: 179 SAVEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLN-RSPNYMDLNNIIALIVSSVT 237 Query: 241 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 300 +LR+PG +N DL + +L+P P HFL + P+ VR T D+ R Sbjct: 238 ASLRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMRGAGQEGQVR-TNFPDLARETFAQ 296 Query: 301 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 360 N + Y+A + +G+V V +++ I RK N+ + PAS + L Sbjct: 297 DNFTAAID---WQQGVYLAASALFRGDVKAKDVDENMATI--RKSLNYASYMPASGGLKL 351 Query: 361 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 420 + P SGL + NHT I+++FER Q+D + A+ + + + D Sbjct: 352 GY-AETAPEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSR---DM 407 Query: 421 MDTSREIVQQLIDEYHAAT 439 M +R + L Y A+ Sbjct: 408 MAKARNQIATLAQSYRDAS 426 >2BTQ-A nrPDB Length = 473 Score = 456 bits (1174), Expect = e-129, Method: Composition-based stats. Identities = 128/444 (28%), Positives = 237/444 (53%), Gaps = 27/444 (6%) Query: 6 ITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKD--VFFY---QADDEHY 60 I + +GQ GNQI FWK +C EHGI P + + A R + FF ++ Y Sbjct: 7 IVVSIGQAGNQIAASFWKTVCLEHGIDP--LTGQTAPGVAPRGNWSSFFSKLGESSSGSY 64 Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGF-SQGEKIHEDIF 119 +PRA+++DLEP VI ++ + L+NP N+ GAG N+A G+ G ++ ++ Sbjct: 65 VPRAIMVDLEPSVIDNVK-ATSGSLFNPANLI--SRTEGAGGNFAVGYLGAGREVLPEVM 121 Query: 120 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMS 179 +D E D D++ G ++ H+I GGTGSG G+ L+E L ++Y + V + +V P+ ++S Sbjct: 122 SRLDYEIDKCDNVGGIIVLHAIGGGTGSGFGALLIESLKEKYGEIPVLSCAVLPSP-QVS 180 Query: 180 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS 239 VV +PYN++ L L ++AD ++ DN AL +A + +I++P+ +N L++ ++ Sbjct: 181 SVVTEPYNTVFALNTLRRSADACLIFDNEALFDLAHRKWNIESPTVDDLNLLITEALAGI 240 Query: 240 TTTLRYPGYMNND--LIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRL 297 T ++R+ G++ + L L+ +L+P P LHFLM + PLT + + + ++++ L Sbjct: 241 TASMRFSGFLTVEISLRELLTNLVPQPSLHFLMCAFAPLTPP-DRSKFEELGIEEMIKSL 299 Query: 298 LQPKNVMVSTGRDRQTNHCYIAILNIIQGEV-DPTQVHKSLQRIRERKLANFIPWGPASI 356 +V + +++ + +G + D +L +RE+ + W P + Sbjct: 300 FDNGSVFAACSPMEGR---FLSTAVLYRGIMEDKPLADAALAAMREKLPLTY--WIPTAF 354 Query: 357 QVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 ++ + +HR S +++AN+T I+ + +R C +DKL +R+AF + E M + Sbjct: 355 KIGYVEQPGI---SHRKSMVLLANNTEIARVLDRICHNFDKLWQRKAFANWYLNEGMSE- 410 Query: 417 NFDEMDTSREIVQQLIDEYHAATR 440 ++++ R Q+L+ Y A Sbjct: 411 --EQINVLRASAQELVQSYQVAEE 432 >3ZID-A nrPDB Length = 373 Score = 143 bits (360), Expect = 2e-34, Method: Composition-based stats. Identities = 43/231 (18%), Positives = 91/231 (39%), Gaps = 36/231 (15%) Query: 5 IITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRA 64 ++ L +GQCGN+I +Q G R ++ + + Sbjct: 4 VLMLGVGQCGNRILDAVNRQA-----------------FGGSRLAKYYSKQRFPSRV-ET 45 Query: 65 VLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDR 124 + ++ + + + + N+ G G N + G + E I + I++ Sbjct: 46 IAINTAINDLKELKFTAAKDRLHVPNL------HGVGANRSKGKQGFWENQEMILEEIEK 99 Query: 125 EADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQ 184 D + + S++GGTGS ++ L RY + +V P ++E + + Sbjct: 100 RGD----FDLIFVMTSVSGGTGSSFSPLMIHELKKRYKNATIVPIAVLPFREEGT---IY 152 Query: 185 PYNSLLTLKRLTQ-NADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVST 234 N+ L+ + + AD ++++DN L R + D ++ +IN +V+ Sbjct: 153 LQNAAFCLREMIEVEADGMILVDNQYLKRFSGD----IASAYDRINTMVAQ 199 >4XCQ-A nrPDB Length = 318 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 51/129 (39%), Gaps = 11/129 (8%) Query: 84 KLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAG 143 L + ++ Y + G G + ++ I I + D + + ++AG Sbjct: 44 SLKHAKHTYHIPYAEGCGKERKKAVGYAQTYYKQIIAQIMEKFSSCDIV---IFVATMAG 100 Query: 144 GTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADC-- 201 GTGSG+ +L YP K V P + ++ + + N++ + ++ + Sbjct: 101 GTGSGITPPILGLAKQMYPNKHFGFVGVLP---KATEDIDEHMNAIACWNDIMRSTNEGK 157 Query: 202 ---VVVLDN 207 + +LDN Sbjct: 158 DISIYLLDN 166 >3V3T-A nrPDB Length = 360 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 50/129 (38%), Gaps = 11/129 (8%) Query: 84 KLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAG 143 L + ++ Y + G G + ++ I I + D + + ++AG Sbjct: 44 SLKHAKHTYHIPYAEGCGKERKKAVGYAQTYYKQIIAQIMEKFSSCDIV---IFVATMAG 100 Query: 144 GTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADC-- 201 G GSG+ +L YP K V P + ++ + + N++ + ++ + Sbjct: 101 GAGSGITPPILGLAKQMYPNKHFGFVGVLP---KATEDIDEHMNAIACWNDIMRSTNEGK 157 Query: 202 ---VVVLDN 207 + +LDN Sbjct: 158 DISIYLLDN 166 >2R6R-1 nrPDB Length = 338 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 68/163 (41%), Gaps = 9/163 (5%) Query: 101 GNNWASGFSQGEK---IHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERL 157 G G G K E + ID+ + + + + GGTG+G ++ + Sbjct: 58 GEKVTRGLGAGAKPEVGEEAALEDIDKIKEILRDTDMVFISAGLGGGTGTGAAP-VIAKT 116 Query: 158 NDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDR 217 L + P + E + +L L++L +++D +V+ N + ++ Sbjct: 117 AKEMG-ILTVAVATLPFRFEGPRKM---EKALKGLEKLKESSDAYIVIHNDKIKELSNRT 172 Query: 218 LHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL 260 L I++ +F +++ ++S + T+ + P +N D + +L Sbjct: 173 LTIKD-AFKEVDSVLSKAVRGITSIVVTPAVINVDFADVRTTL 214 >4B46-A nrPDB Length = 395 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 29/137 (21%), Positives = 53/137 (38%), Gaps = 10/137 (7%) Query: 96 HGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLE 155 G G G + G E+ +++ ID ++ F++ + GGTGSG L + Sbjct: 64 KGHGVGADNELGAEIAEEDIDEVQGAIDSI--PVHEVDAFLVVSGLGGGTGSGGAPVLAK 121 Query: 156 RLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAT 215 L Y + V + P DE + N+ + + + D ++V DN A Sbjct: 122 HLKRIYTE-PVYGLGILPGSDEGG---IYTLNAARSFQTFVREVDNLLVFDNDAW----R 173 Query: 216 DRLHIQNPSFSQINQLV 232 + +IN+ + Sbjct: 174 KTGESVQGGYDEINEEI 190 >2CH6-A nrPDB Length = 344 Score = 37.0 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 36/78 (46%) Query: 85 LYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGG 144 L + + L+E G + N+W G + + ++ + R+A + L S++GG Sbjct: 19 LVSEDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGG 78 Query: 145 TGSGLGSYLLERLNDRYP 162 G L+E L DR+P Sbjct: 79 DQEDAGRILIEELRDRFP 96 >4B45-A nrPDB Length = 349 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 13/148 (8%) Query: 89 ENIYLSEH---GGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGT 145 E + + + G G G + G + E ++ +D + E + + GG+ Sbjct: 50 ETVLIGQDRVNGHGVGGDNELGAAVMESDQTEVMSALDGRV--TAEAESIFVVAGLGGGS 107 Query: 146 GSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVL 205 GSG L + L Y V + P DE + + N+ +LK + + AD V+++ Sbjct: 108 GSGGAPVLAKALAGVY-DVPVYVLGILPGADEGA---LYQVNAGRSLKTVAREADAVLLV 163 Query: 206 DNTALNRIATDRLHIQNPSFSQINQLVS 233 DN A R A + + + + IN+ ++ Sbjct: 164 DNDA-FRSAGESM---SEGYDAINEAIA 187 >6G58-A nrPDB Length = 404 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 32/215 (14%), Positives = 69/215 (32%), Gaps = 39/215 (18%) Query: 246 PGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMV 305 YMN DL + ++ LH T + ++ A + V R L++ Sbjct: 30 SAYMNVDLNAVASNFKVFSTLH---PNKTVMAVVKANAY--GLGSVKVARHLMENGATFF 84 Query: 306 STGRDRQTNHCYI---AILNIIQGEVDPTQVHKSLQRIRERKLANFIP--WGPASIQVAL 360 + + + ++ G + + K+ I+ R W +I+ Sbjct: 85 AVATLDEAIELRMHGITAKILVLGVLPAKDIDKA---IQHRVALTVPSKQWLKEAIKNIS 141 Query: 361 SRKSPYLPSAHRVSGLM----MANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKD 416 + L ++ M + + + + E +QY++L +F+ Sbjct: 142 GEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIE-IIQQYEQL--------------VFEG 186 Query: 417 NFDEMDTSREIVQQLIDEYH-------AATRPDYI 444 F + E ++Y A +P+YI Sbjct: 187 VFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYI 221 >1OFU-A nrPDB Length = 320 Score = 35.1 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 65/167 (38%), Gaps = 17/167 (10%) Query: 96 HGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLE 155 G GAG N G + E I ++++ + + + GGTG+G + E Sbjct: 67 KGLGAGANPEVGRQAALEDRERISEVLE-------GADMVFITTGMGGGTGTGAAPIIAE 119 Query: 156 RLNDRYPKKLVQTYSVF--PNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRI 213 + + T +V P E + + ++ L ++ D ++ + N L I Sbjct: 120 VAKE----MGILTVAVVTRPFPFEGRKRM---QIADEGIRALAESVDSLITIPNEKLLTI 172 Query: 214 ATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL 260 + +F++ + +++ + + ++ PG +N D + + Sbjct: 173 LGKDASLLA-AFAKADDVLAGAVRGISDIIKRPGMINVDFADVKTVM 218 >2VAW-A nrPDB Length = 394 Score = 35.1 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 65/167 (38%), Gaps = 17/167 (10%) Query: 96 HGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLE 155 G GAG N G + E I ++++ + + + GGTG+G + E Sbjct: 67 KGLGAGANPEVGRQAALEDRERISEVLE-------GADMVFITTGMGGGTGTGAAPIIAE 119 Query: 156 RLNDRYPKKLVQTYSVF--PNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRI 213 + + T +V P E + + ++ L ++ D ++ + N L I Sbjct: 120 VAKE----MGILTVAVVTRPFPFEGRKRM---QIADEGIRALAESVDSLITIPNEKLLTI 172 Query: 214 ATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL 260 + +F++ + +++ + + ++ PG +N D + + Sbjct: 173 LGKDASLLA-AFAKADDVLAGAVRGISDIIKRPGMINVDFADVKTVM 218 >5T6E-A nrPDB Length = 411 Score = 34.7 bits (78), Expect = 0.084, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 22/56 (39%), Gaps = 7/56 (12%) Query: 359 ALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQY----DKLRK---REAFLEQ 407 +S++ L + L + N T + L++ Y + + + ++FL Sbjct: 30 KVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHW 85 >4XD9-B nrPDB Length = 221 Score = 32.4 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 15/42 (35%) Query: 22 WKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPR 63 W+ + GI A +R+ Y + ++PR Sbjct: 113 WELFARKKGIGKYSNKPGAALADKERRKKLVYDEESGEWVPR 154 >6GI9-A nrPDB Length = 373 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 17/124 (13%), Positives = 37/124 (29%), Gaps = 16/124 (12%) Query: 16 QIGFEFWKQLCAEHG-ISPEGIVEEFATEGTDRKDVFFYQADDEHY-----IPRAVLLDL 69 +I + W H I P G A+ + PRA+ LD Sbjct: 97 RIAVQLWHTGRLSHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRALELDE 156 Query: 70 EPRVIHSILNS---------PYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKI-HEDIF 119 P +++ + +L++ L + + N + + + Sbjct: 157 IPGIVNDFRQAVANAREAGFDLVELHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVL 216 Query: 120 DIID 123 +++D Sbjct: 217 EVVD 220 >2VAP-A nrPDB Length = 364 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 5/100 (5%) Query: 162 PKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDR-LHI 220 K T +V + + V+ N++ L+RL Q+ D +VV+ N L I + L + Sbjct: 148 KKIGALTVAVVTLPF-VMEGKVRMKNAMEGLERLKQHTDTLVVIPNEKLFEIVPNMPLKL 206 Query: 221 QNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL 260 +F ++++ + + G +N D + A + Sbjct: 207 ---AFKVADEVLINAVKGLVELITKDGLINVDFADVKAVM 243 >1QF6-A nrPDB Length = 642 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 8/60 (13%), Positives = 20/60 (33%) Query: 390 RTCRQYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEYHAATRPDYISWGTQ 449 R C + ++ A+ M + + ++ + + A + D+ G Q Sbjct: 191 RFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQ 250 >1BWR-A nrPDB Length = 233 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 2/58 (3%) Query: 30 GISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYN 87 G+ P G E R + A H PRA LD +P +HS + +Y+ Sbjct: 137 GLLPRGQHPNPLREKNRRVNELVRAALAGH--PRAHFLDADPGFVHSDGTISHHDMYD 192 >4EI8-A nrPDB Length = 389 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 45/268 (16%), Positives = 94/268 (35%), Gaps = 28/268 (10%) Query: 54 QADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEK 113 Q + Y RA+L++ + + I + I L + GA N G K Sbjct: 40 QIKNNKYPYRAILVNTNSQDFNKIEIKNTGNV---RKIQLEGYEQGAARNPQVGEEAFVK 96 Query: 114 IHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLND-RYPKKLVQTYSVF 172 IF+ + +E + D + + GGTG+G +E L + Y + + Sbjct: 97 HETKIFEAVKQEFEDRDF---IWITCGLGGGTGTGALLKAIEMLYEHDY------NFGLL 147 Query: 173 PNQDEMSDVVVQPYNSLLTLKRLTQNADC---VVVLDNTALNRIATDRLHIQNPSFSQIN 229 ++ + N+ ++ + N + +V++DN L + +NPS Sbjct: 148 LTLPRDAEALKVLENATSRIRSIAMNQEAFGSIVLIDNAKLY----RKFEEENPS----- 198 Query: 230 QLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTT 289 + ++ + +Y +++ + +S P HF + + + V S+ K Sbjct: 199 ---ALANEYTSYSNKYIADALHEINLVTSSFTPFSDTHFDASEFAQVINTPGVLSLAKLE 255 Query: 290 VLDVMRRLLQPKNVMVSTGRDRQTNHCY 317 + P + G + Y Sbjct: 256 LKSNQLDTENPLGYLTQLGNALEKGVLY 283 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.132 0.354 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,526,308 Number of Sequences: 36641 Number of extensions: 638156 Number of successful extensions: 2052 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 1820 Number of HSP's gapped (non-prelim): 74 length of query: 451 length of database: 10,336,785 effective HSP length: 100 effective length of query: 351 effective length of database: 6,672,685 effective search space: 2342112435 effective search space used: 2342112435 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)