BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P22748 (312 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5JN8-A nrPDB 559 e-160 3ZNC-A nrPDB 315 2e-86 4LU3-A nrPDB 140 1e-33 1RJ5-A nrPDB 139 1e-33 5LL9-A nrPDB 137 7e-33 6G4T-A nrPDB 137 8e-33 3FE4-A nrPDB 131 4e-31 1Z93-A nrPDB 123 9e-29 4QK3-A nrPDB 122 2e-28 3D0N-A nrPDB 120 1e-27 1FLJ-A nrPDB 115 3e-26 5DVX-A nrPDB 113 1e-25 1URT-A nrPDB 112 2e-25 2W2J-A nrPDB 112 2e-25 6FAF-A nrPDB 106 1e-23 4XIW-A nrPDB 105 2e-23 4CNR-A nrPDB 105 2e-23 4X5S-A nrPDB 99 2e-21 4COQ-A nrPDB 93 2e-19 6EKI-A nrPDB 88 5e-18 4ETQ-X nrPDB 88 5e-18 5HPJ-A nrPDB 88 5e-18 6B9J-X nrPDB 88 5e-18 4G7A-A nrPDB 87 7e-18 4XZ5-A nrPDB 84 7e-17 4TWL-A nrPDB 82 4e-16 1KOQ-A nrPDB 70 1e-12 1Y7W-A nrPDB 67 7e-12 3Q31-A nrPDB 64 7e-11 5TT3-A nrPDB 60 2e-09 3B1B-A nrPDB 52 4e-07 4UM8-B nrPDB 30 1.4 4UM9-D nrPDB 29 2.0 5Y34-A nrPDB 28 5.0 1Y1X-A nrPDB 28 5.5 2YCH-A nrPDB 27 8.6 6MSN-A nrPDB 27 9.4 >5JN8-A nrPDB Length = 266 Score = 559 bits (1440), Expect = e-160, Method: Compositional matrix adjust. Identities = 266/266 (100%), Positives = 266/266 (100%) Query: 19 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK Sbjct: 1 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 60 Query: 79 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME Sbjct: 61 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 120 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT Sbjct: 121 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 180 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY Sbjct: 181 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 240 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 DKEQTVSMKDNVRPLQQLGQRTVIKS Sbjct: 241 DKEQTVSMKDNVRPLQQLGQRTVIKS 266 >3ZNC-A nrPDB Length = 258 Score = 315 bits (806), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 148/264 (56%), Positives = 191/264 (72%), Gaps = 6/264 (2%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 WCYE+Q E CL P KW G C++++QSPINIVT + KV+ +L F GYD+KQ W Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 60 Query: 83 VQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIV 142 ++NN H+V M L A I GG LPA Y+A QLHLHWS+ GSEHS+DG HFAMEMHIV Sbjct: 61 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 120 Query: 143 HEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAES 202 H+K + +D +D+ AVLAF++E G +VN+GFQPLVEAL +I KP ++T+ ES Sbjct: 121 HKKLTSSK------EDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRES 174 Query: 203 SLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQ 262 SL D+LP K+ YFRY GSLTTP CDE V+WTV+++PI++H+ Q L FS+ LYYD++Q Sbjct: 175 SLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQ 234 Query: 263 TVSMKDNVRPLQQLGQRTVIKSGA 286 ++MKDNVRPLQ LG+R V KS A Sbjct: 235 KLNMKDNVRPLQPLGKRQVFKSHA 258 >4LU3-A nrPDB Length = 279 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/272 (34%), Positives = 135/272 (49%), Gaps = 14/272 (5%) Query: 17 ASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD 76 A HW YE ++P P C + QSPI+I T D L GYD Sbjct: 1 ADGGQHWTYEGPHGQDHWPASYP-----ECGNNAQSPIDIQTDSVTFDPDLPALQPHGYD 55 Query: 77 KKQT--WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPY-KGSEHSLDGE 133 + T + NNGH+V + L +++ GGLP Y A QLHLHW GSEH ++ E Sbjct: 56 QPGTEPLDLHNNGHTVQLSL--PSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSE 113 Query: 134 HFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKP 193 E+HIVH + + ++ EA + +AVL L+E G N ++ ++ L + Sbjct: 114 ATFAELHIVH-YDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHK 172 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 + T++ +L +LLPK+ L YFRY GSLTTP C + V+WTVF Q+ EQ+ Sbjct: 173 DQKTSVPPFNLRELLPKQ--LGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQ 230 Query: 254 QKLYYDKEQTVS-MKDNVRPLQQLGQRTVIKS 284 L+ +E+ + N R LQ L QR V S Sbjct: 231 GTLFSTEEEPSKLLVQNYRALQPLNQRMVFAS 262 >1RJ5-A nrPDB Length = 261 Score = 139 bits (351), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 94/267 (35%), Positives = 132/267 (49%), Gaps = 14/267 (5%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQT- 80 HW YE ++P P C D QSPINI T D L GYD+ T Sbjct: 4 HWTYEGPHGQDHWPTSYP-----ECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTE 58 Query: 81 -WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDL-PYKGSEHSLDGEHFAME 138 + NNGH+V + L ++ GGLP Y A QLHLHW +GSEH ++ E A E Sbjct: 59 PLDLHNNGHTVQLSL--PPTLHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAE 116 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 +H+VH + S + AQ P+ +AVL L+E G N + ++ L I + T+ Sbjct: 117 LHVVHYDSQSYSSLSEAAQKPQG-LAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTS 175 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 + S+ +L P+ +L +FRY GSLTTP C + V+WTVF Q+ Q+ + L Sbjct: 176 VPPFSVRELFPQ--QLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSS 233 Query: 259 DKEQ-TVSMKDNVRPLQQLGQRTVIKS 284 +E + + N R Q L QRT+ S Sbjct: 234 TEEDPSEPLVQNYRVPQPLNQRTIFAS 260 >5LL9-A nrPDB Length = 263 Score = 137 bits (344), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 132/247 (53%), Gaps = 14/247 (5%) Query: 45 NCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD--KKQTWTVQNNGHSVMMLLENKASISG 102 +C QSPI++ + + D L F GY+ + + + NNGHSV + L + I G Sbjct: 21 SCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQG 80 Query: 103 GGLPAPYQAKQLHLHWSD--LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPE 160 L + Y A QLHLHW + P+ GSEH++ G+HFA E+HIVH + A + Sbjct: 81 --LQSRYSATQLHLHWGNPNDPH-GSEHTVSGQHFAAELHIVHYNSD-LYPDASTASNKS 136 Query: 161 DEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRY 220 + +AVLA L+E G+ N + + L ++ + ++ +LLP E+ Y+RY Sbjct: 137 EGLAVLAVLIEMGS-FNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLP--ERTAEYYRY 193 Query: 221 LGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLY---YDKEQTVSMKDNVRPLQQLG 277 GSLTTP C+ V+WTVFR P+Q+ +EQ+LA LY D M +N R +Q+ Sbjct: 194 RGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFD 253 Query: 278 QRTVIKS 284 +R V S Sbjct: 254 ERLVYTS 260 >6G4T-A nrPDB Length = 274 Score = 137 bits (344), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 93/269 (34%), Positives = 134/269 (49%), Gaps = 21/269 (7%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 W Y S++ L P+ Q DRQSPINI++++A L S Y+ + + Sbjct: 9 WGYGQDDGPSHWHKLYPI-----AQGDRQSPINIISSQAVYSPSLQPLELS-YEACMSLS 62 Query: 83 VQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + NNGHSV + +++ ++GG L PY+ KQ H HW GSEH++DG+ F E+ Sbjct: 63 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 122 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH K S EA D +AV+ +E G + + L +AL + T Sbjct: 123 HLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMV---RFKGTK 177 Query: 200 AESSLLD---LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 256 A+ S + LLP RHY+ Y GSLTTP E V W V REPI + Q+ F L Sbjct: 178 AQFSCFNPKSLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLL 234 Query: 257 YY-DKEQTVSMKDNVRPLQQLGQRTVIKS 284 + + ++ + M +N RP Q L R V S Sbjct: 235 FTSEDDERIHMVNNFRPPQPLKGRVVKAS 263 >3FE4-A nrPDB Length = 278 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 91/276 (32%), Positives = 142/276 (51%), Gaps = 22/276 (7%) Query: 21 SHWCYEVQA-ESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79 S W Y A + +++P P C RQSPIN+ TK + + L +GY+ + Sbjct: 2 SDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA 56 Query: 80 -TWTVQNNGHSVMMLLEN--KASISGGGLPAPYQAKQLHLHW--SDLPYKGSEHSLDGEH 134 + + NNGH+V + L + + +++ G + Y A+Q+H HW + GSEH++DG Sbjct: 57 GEFPMVNNGHTVQISLPSTMRMTVADGTV---YIAQQMHFHWGGASSEISGSEHTVDGIR 113 Query: 135 FAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQ-VNEGFQPLVEALSNIPKP 193 +E+HIVH K S ++ AQD D +AVLA VE N + + L+NI P Sbjct: 114 HVIEIHIVHYNSKYKSYDI--AQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 171 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 TT+ + D+LP+ L+HY+ Y GSLTTP C E V W V + ++L R Q+ Sbjct: 172 GQRTTLTGLDVQDMLPR--NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLE 229 Query: 254 QKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289 L + +T+ ++ R Q L R V++S P + Sbjct: 230 NSLLDHRNKTI--HNDYRRTQPLNHR-VVESNFPNQ 262 >1Z93-A nrPDB Length = 266 Score = 123 bits (309), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 83/266 (31%), Positives = 126/266 (47%), Gaps = 16/266 (6%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 W Y ++ L P N + + QSPI + T + D L + S YD T Sbjct: 5 WGYASHNGPDHWHELFP-----NAKGENQSPIELHTKDIRHDPSLQPWSVS-YDGGSAKT 58 Query: 83 VQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + NNG + ++ ++ ++ + GG LP PY+ +Q HLHW GSEH++DG +A E+ Sbjct: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAEL 118 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH K + KEA D IAV+ ++ G + E FQ ++AL I Sbjct: 119 HLVHWNPKYNT--FKEALKQRDGIAVIGIFLKIGHENGE-FQIFLDALDKIKTKGKEAPF 175 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY- 258 + L P R Y+ Y GS TTP C+E +VW + +EP+ + +Q+ L Sbjct: 176 TKFDPSSLFPAS---RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSA 232 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 + E V + N RP Q + R V S Sbjct: 233 ENEPPVPLVSNWRPPQPINNRVVRAS 258 >4QK3-A nrPDB Length = 249 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 92/266 (34%), Positives = 128/266 (48%), Gaps = 25/266 (9%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 HW Y ++ P+ + +RQSP++I T AK D L S YD+ + Sbjct: 4 HWGYGKHNGPEHWHKDFPI-----AKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSL 57 Query: 82 TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 + NNGH+ + ++ KA + GG L Y+ Q H HW L +GSEH++D + +A E Sbjct: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 +H+VH K K Q P D +AVL ++ G+ G Q +V+ L +I S Sbjct: 118 LHLVHWNTKYGDFG-KAVQQP-DGLAVLGIFLKVGS-AKPGLQKVVDVLDSIKTKGKSAD 174 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 LLP E L Y+ Y GSLTTP E V W V +EPI + EQ+L F +KL Sbjct: 175 FTNFDPRGLLP--ESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKF-RKL-- 228 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 M DN RP Q L R + S Sbjct: 229 -------MVDNWRPAQPLKNRQIKAS 247 >3D0N-A nrPDB Length = 264 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 86/263 (32%), Positives = 121/263 (46%), Gaps = 15/263 (5%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 W Y ++ P+ G D+QSPI I T + K D L R YD Sbjct: 8 WGYREHNGPIHWKEFFPIADG-----DQQSPIEIKTKEVKYDSSL-RPLSIKYDPSSAKI 61 Query: 83 VQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + N+GHS + ENK+ + GG L Y+ +Q+HLHW GSEH +DG +A E+ Sbjct: 62 ISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAEL 121 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH V+ A +P D +AVL ++ G + N Q + + L +I + T Sbjct: 122 HVVHWNSDKYPSFVEAAHEP-DGLAVLGVFLQIG-EPNSQLQKITDTLDSIKEKGKQTRF 179 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL-YY 258 LL LLP Y+ Y GSLT P E V W V ++PI + +Q+ F L Sbjct: 180 TNFDLLSLLPPSWD---YWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTA 236 Query: 259 DKEQTVSMKDNVRPLQQLGQRTV 281 + E + N RP Q L R V Sbjct: 237 EGEAAAFLVSNHRPPQPLKGRKV 259 >1FLJ-A nrPDB Length = 260 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 84/267 (31%), Positives = 127/267 (47%), Gaps = 18/267 (6%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 W Y ++ L P+ G D QSPI + T + D L + S YD T Sbjct: 5 WGYASHNGPEHWHELYPIAKG-----DNQSPIELHTKDIRHDPSLQPWSVS-YDPGSAKT 58 Query: 83 VQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + NNG + ++ ++ ++ + GG L PY+ +Q HLHW GSEH++DG +A E+ Sbjct: 59 ILNNGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAEL 118 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH K + EA D IAV+ ++ G + E FQ L++AL I Sbjct: 119 HLVHWNPKYNT--FGEALKQPDGIAVVGIFLKIGREKGE-FQILLDALDKIKTKGKEAPF 175 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLY-- 257 L P R Y+ Y GS TTP C+E +VW + +EP+ + +Q +A + L+ Sbjct: 176 NHFDPSCLFP---ACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQ-MAKLRSLFAS 231 Query: 258 YDKEQTVSMKDNVRPLQQLGQRTVIKS 284 + E V + N RP Q + R V S Sbjct: 232 AENEPPVPLVGNWRPPQPIKGRVVRAS 258 >5DVX-A nrPDB Length = 260 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/266 (31%), Positives = 121/266 (45%), Gaps = 19/266 (7%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ-- 79 HW Y +P + P C QSP++I A L SG+ Sbjct: 1 HWRY---GGDPPWPRVSPA-----CAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLP 52 Query: 80 TWTVQNNGHSVMMLLENKASISGGGLPA-PYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 ++NNGHSV + L + G P Y+A QLHLHW GSEH+++G F E Sbjct: 53 ELRLRNNGHSVQLTLPPGLEMKLG--PGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAE 110 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 +H+VH K V EA +AVLA +E G + N ++ L+ L I + T Sbjct: 111 IHVVHLSTK--YARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQ 168 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 + + LLP + YF+Y GSLTTP C + V+WTVF + + L +Q+ S L+ Sbjct: 169 VPGLDISALLPSD--FSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWG 226 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 + + + N R Q L R + S Sbjct: 227 PGDSRLQL--NFRATQPLNGRVIEAS 250 >1URT-A nrPDB Length = 248 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/239 (32%), Positives = 115/239 (48%), Gaps = 10/239 (4%) Query: 50 RQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLEN---KASISGGGLP 106 RQSPINI + D +L S YD + N GH+ + ++ + ISGG L Sbjct: 6 RQSPINIQWKDSVYDPQLAPLRVS-YDAASCRYLWNTGHAFQVEFDDSCEDSGISGGPLG 64 Query: 107 APYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVL 166 Y+ KQ H HW GSEH++DG + E+H+VH N K+A E+ +AV+ Sbjct: 65 NHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNST-KYENYKKASVGENGLAVI 123 Query: 167 AFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTT 226 ++ G ++ Q LV+ L + + M + L+P R Y+ Y GSLTT Sbjct: 124 GVFLKLGAH-HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMP---ACRDYWTYPGSLTT 179 Query: 227 PTCDEKVVWTVFREPIQLHREQILAFSQKLYYDK-EQTVSMKDNVRPLQQLGQRTVIKS 284 P E V W V + P+++ Q+ F L+ + E+ M +N RPLQ L R + S Sbjct: 180 PPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSS 238 >2W2J-A nrPDB Length = 291 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 130/254 (51%), Gaps = 15/254 (5%) Query: 40 VKWG---GNCQKDRQSPINIVTTKAKVDKKLGRFFFS-GYDKKQTWTVQNNGHSVMMLLE 95 V+WG + + QSPIN+ + +A+ D L S Y + V N+GH++ ++L+ Sbjct: 36 VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILK 95 Query: 96 NKASISGGGLPA--PYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNV 153 +K+ +SGG LP ++ ++ HW +GSEH+++ + F ME+H++H ++ Sbjct: 96 SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNST-LFGSI 154 Query: 154 KEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEK 213 EA IA++A V+ G + + G + + E L +I S T+ + LLP + Sbjct: 155 DEAVGKPHGIAIIALFVQIGKE-HVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLP-DPL 212 Query: 214 LRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVS------MK 267 LR Y+ Y GSLT P C E V W +FR P+ + + QI F + + K + + Sbjct: 213 LRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILG 272 Query: 268 DNVRPLQQLGQRTV 281 DN RP Q L R + Sbjct: 273 DNFRPTQPLSDRVI 286 >6FAF-A nrPDB Length = 261 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 81/270 (30%), Positives = 121/270 (44%), Gaps = 15/270 (5%) Query: 19 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78 A W Y+ + + L P+ G N QSP++I T++ K D L S Y+ Sbjct: 2 ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55 Query: 79 QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135 + N GHS + E N++ + GG Y+ Q H HW GSEH++DG + Sbjct: 56 TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115 Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195 + E+H+ H S ++ EA D +AV+ L++ G + N Q +++AL I Sbjct: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173 Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255 LLP ++ Y GSLT P E V W + +E I + EQ+ F Sbjct: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230 Query: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTVIKS 284 L + + V M+ N RP Q L RTV S Sbjct: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260 >4XIW-A nrPDB Length = 239 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 87/252 (34%), Positives = 118/252 (46%), Gaps = 37/252 (14%) Query: 39 PVKWGGNCQKD-RQSPINIV--TTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMML-- 93 P W G C RQSPINI T+ KVD ++G F F+ Y + V N GH M + Sbjct: 12 PPTWKGVCATGKRQSPINIPLNTSAPKVDAEMGEFDFA-YGSFEKCDVLNTGHGTMQVNF 70 Query: 94 -LENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRN 152 N A I L + Q H H SEH++DG +AME H+VH K K T Sbjct: 71 PAGNLAFIGNMEL----ELLQFHFHAP------SEHAMDGRRYAMEAHLVH-KNKSTGN- 118 Query: 153 VKEAQDPEDEIAVLAFLVEAGTQV-NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKE 211 +AVL ++E G + N +E +P + + + ++ LLPK+ Sbjct: 119 ----------LAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSPKGINPVM-LLPKK 167 Query: 212 EK--LRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDN 269 K R + Y GSLTTP C E V W VF +PI++ QIL F + + +K + N Sbjct: 168 SKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFVGDNK----TYATN 223 Query: 270 VRPLQQLGQRTV 281 RPLQ L R V Sbjct: 224 TRPLQLLNSRLV 235 >4CNR-A nrPDB Length = 262 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 85/269 (31%), Positives = 127/269 (47%), Gaps = 26/269 (9%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 HW Y+ ++ P+ G +RQSP++I T D L Y + + Sbjct: 6 HWGYDKHNGPEHWHKDFPIANG-----ERQSPVDIDTDAVVQDPALKPLALD-YGEATSR 59 Query: 82 TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 + N+GHS + ++ KA + G L Y+ Q H HW +GSEH++D + +A E Sbjct: 60 RMVNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAE 119 Query: 139 MHIVHEKEK----GTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPE 194 +H+VH K GT+ AQ+P D +AV+ ++ G N Q +++AL +I Sbjct: 120 LHLVHWNTKYGDFGTA-----AQEP-DGLAVVGVFLKVG-DANPALQKVLDALDSIKTKG 172 Query: 195 MSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQ 254 ST LLP + Y+ Y GSLTTP E V W V +EPI + +Q+L F + Sbjct: 173 KSTDFPNFDPGSLLP---NVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKF-R 228 Query: 255 KLYYDKEQTVS--MKDNVRPLQQLGQRTV 281 L ++ E M N RP Q L R V Sbjct: 229 TLNFNAEGEPEELMLANWRPAQPLKNRQV 257 >4X5S-A nrPDB Length = 232 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 128/267 (47%), Gaps = 46/267 (17%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 HW YE + N+ L P + C QSP++I + KV KL + + Y+K Sbjct: 9 HWSYEGENGPENWAKLNPEYFW--CNLKNQSPVDI-SDNYKVHAKLEKLHIN-YNKAVNP 64 Query: 82 TVQNNGHSVMM-LLEN-KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + NNGH++ + +LE+ K +I G Y KQ H H SEH+++G+++ +EM Sbjct: 65 EIVNNGHTIQVNVLEDFKLNIKG----KEYHLKQFHFH------APSEHTVNGKYYPLEM 114 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH +D + IAV+ + G E L + N K E S Sbjct: 115 HLVH-------------KDKDGNIAVIGVFFKEGKANPE----LDKVFKNALKEEGSKVF 157 Query: 200 AESSLLD-LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 S ++ LLP +++Y+ Y GSLTTP C E V+W V ++PI ++QI F Sbjct: 158 DGSININALLPP---VKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELF------ 208 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKSG 285 +++ +N RP Q + R +++S Sbjct: 209 ---KSIMKHNNNRPTQPINSRYILESN 232 >4COQ-A nrPDB Length = 247 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 80/269 (29%), Positives = 118/269 (43%), Gaps = 53/269 (19%) Query: 22 HWCYEVQAESSNYPCLVP----VKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDK 77 HW Y ++ L P K G N QSPI+I + A V L S Y Sbjct: 25 HWGYSGSIGPEHWGDLSPEYLMCKIGKN-----QSPIDINSADA-VKACLAPV--SVYYV 76 Query: 78 KQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAM 137 V NNGH++ +++ + + G + KQ H H SEH+++G+H+ Sbjct: 77 SDAKYVVNNGHTIKVVMGGRGYVVVDG--KRFYLKQFHFH------APSEHTVNGKHYPF 128 Query: 138 EMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMST 197 E H VH + G I VL + G + P +E + + E Sbjct: 129 EAHFVHLDKNGN-------------ITVLGVFFKVGKE-----NPELEKVWRVMPEEPGQ 170 Query: 198 TMAESSLLD---LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQ 254 ++ +D LLP+ R Y+RY GSLTTP C E V W VF+EP+++ REQ+ F + Sbjct: 171 KRHLTARIDPEKLLPEN---RDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRK 227 Query: 255 KLYYDKEQTVSMKDNVRPLQQLGQRTVIK 283 + + DN RP+Q L R V+K Sbjct: 228 VMGF---------DNNRPVQPLNARKVMK 247 >6EKI-A nrPDB Length = 226 Score = 88.2 bits (217), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 54/269 (20%) Query: 21 SHWCYEVQAESSNYPCL----VPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD 76 HW Y + ++ L + K G N QSP++I +K+ + SG Sbjct: 4 GHWSYHGETGPQHWGDLKNEYIMCKIGKN-----QSPVDISRIVEAELEKIKINYSSGGS 58 Query: 77 KKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 136 ++ NNGH++ + E + I G+ ++ KQ H H SEH++ G+ + Sbjct: 59 -----SITNNGHTIKVSYEPGSYIIVDGIR--FELKQFHFHAP------SEHTIKGKSYP 105 Query: 137 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEAL-SNIPKPEM 195 E H VH D + +AV+ + + G + P++E + N+P+ Sbjct: 106 FEAHFVH-------------ADKDGNLAVIGVIFKEGKK-----NPIIEKIWENLPEAGK 147 Query: 196 STTMAES-SLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQ 254 + +A + DLLPK++K Y+RY GSLTTP C E V W V E ++L +EQI F + Sbjct: 148 TIKLAHKINAYDLLPKKKK---YYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRK 204 Query: 255 KLYYDKEQTVSMKDNVRPLQQLGQRTVIK 283 + D RP+Q L R +++ Sbjct: 205 LM---------GGDTNRPVQPLNARMIME 224 >4ETQ-X nrPDB Length = 269 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 63/202 (31%), Positives = 99/202 (49%), Gaps = 9/202 (4%) Query: 52 SPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQA 111 SPINI T KA + +L Y++ + T+QN G V + + ISGG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIH-YNESKPTTIQNTGKLVRINFKG-GYISGGFLPNEYVL 63 Query: 112 KQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171 LH++W GS H +D ++ E+++VH +K S + +EA+ +D + +++ ++ Sbjct: 64 SSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYS-SYEEAKKHDDGLIIISIFLQ 122 Query: 172 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD-LLPKEEKLRHYFRYLGSLTTPTCD 230 N FQ +V L +I S LD LLP + YF YLG+ + D Sbjct: 123 VLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLD---YFTYLGTTINHSAD 179 Query: 231 EKVVWTVFREPIQLHREQILAF 252 VW +F PI +H +Q+ F Sbjct: 180 --AVWIIFPTPINIHSDQLSKF 199 >5HPJ-A nrPDB Length = 217 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 115/236 (48%), Gaps = 45/236 (19%) Query: 50 RQSPINI-VTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAP 108 Q+PI+I TT+A++ Y+ + T V NNGH++ L K +++ G Sbjct: 25 NQTPIDINQTTQAELAP-----LHLDYEGQVTELV-NNGHTIQANLTGKNTLTVDG--KT 76 Query: 109 YQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAF 168 ++ KQ H H SE+ L G+ + +E H VH +KG E+AV+A Sbjct: 77 FELKQFHFH------TPSENYLKGKQYPLEAHFVHATDKG-------------ELAVVAV 117 Query: 169 LVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAES-SLLDLLPKEEKLRHYFRYLGSLTTP 227 + + G + N L L++IP + + E+ + DLLP++ R Y+R+ GSLTTP Sbjct: 118 MFDFGPRSN---NELTTLLASIPSKGQTVELKEALNPADLLPRD---REYYRFNGSLTTP 171 Query: 228 TCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIK 283 C E V W V +EP S K +K Q V M +N RPLQ L R +++ Sbjct: 172 PCSEGVRWFVMQEP---------QTSSKAQTEKLQAV-MGNNARPLQPLNARLILE 217 >6B9J-X nrPDB Length = 241 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 63/202 (31%), Positives = 99/202 (49%), Gaps = 9/202 (4%) Query: 52 SPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQA 111 SPINI T KA + +L Y++ + T+QN G V + + ISGG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIH-YNESKPTTIQNTGKLVRINFKG-GYISGGFLPNEYVL 63 Query: 112 KQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171 LH++W GS H +D ++ E+++VH +K S + +EA+ +D + +++ ++ Sbjct: 64 SSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYS-SYEEAKKHDDGLIIISIFLQ 122 Query: 172 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD-LLPKEEKLRHYFRYLGSLTTPTCD 230 N FQ +V L +I S LD LLP + YF YLG+ + D Sbjct: 123 VLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLD---YFTYLGTTINHSAD 179 Query: 231 EKVVWTVFREPIQLHREQILAF 252 VW +F PI +H +Q+ F Sbjct: 180 --AVWIIFPTPINIHSDQLSKF 199 >4G7A-A nrPDB Length = 248 Score = 87.4 bits (215), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 77/271 (28%), Positives = 127/271 (46%), Gaps = 44/271 (16%) Query: 14 RPSASAESHWCYEVQAESSNYPCLVP-VKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFF 72 R S E W YE + ++ L P W C+ QSPINI K KV L + Sbjct: 17 RGSHMLEHEWSYEGEKGPEHWAQLKPEFFW---CKLKNQSPINI-DKKYKVKANLPKLNL 72 Query: 73 SGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDG 132 Y + V NNGH++ + ++ +++ G YQ KQ H H SEH+++ Sbjct: 73 Y-YKTAKESEVVNNGHTIQINIKEDNTLNYLG--EKYQLKQFHFH------TPSEHTIEK 123 Query: 133 EHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPK 192 + + +E+H VH+ E G +I V+ + + G E L + L+ P Sbjct: 124 KSYPLEIHFVHKTEDG-------------KILVVGVMAKLGKTNKE----LDKILNVAPA 166 Query: 193 PEMSTTMAESSLLDL-LPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILA 251 E + ++ L+ +PK+++ Y Y GSLTTP C E V W V ++PI + ++Q+ Sbjct: 167 EEGEKILDKNLNLNNLIPKDKR---YMTYSGSLTTPPCTEGVRWIVLKKPISISKQQL-- 221 Query: 252 FSQKLYYDKEQTVSMKDNVRPLQQLGQRTVI 282 +K ++V + N RP+Q++ R +I Sbjct: 222 -------EKLKSVMVNPNNRPVQEINSRWII 245 >4XZ5-A nrPDB Length = 233 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/253 (28%), Positives = 110/253 (43%), Gaps = 44/253 (17%) Query: 39 PVKWG------GNCQKDR-QSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVM 91 P WG C+ + QSPIN+ A L F Y ++ + NNGH++ Sbjct: 12 PQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGF--DVYYRETALKLINNGHTLQ 69 Query: 92 MLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSR 151 + + + I G Y+ Q H H SEH DG ++ MEMH+VH Sbjct: 70 VNIPLGSYIKING--HRYELLQYHFH------TPSEHQRDGFNYPMEMHLVH-------- 113 Query: 152 NVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKE 211 +D + +AV+A L + G + NE L+ L K + + P + Sbjct: 114 -----KDGDGNLAVIAILFQEGEE-NETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPAD 167 Query: 212 EKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVR 271 +K +++Y GSLTTP C E V W VF++PIQ Q+ + L N R Sbjct: 168 KK---FYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYL----------GSNAR 214 Query: 272 PLQQLGQRTVIKS 284 P+Q+ RT++KS Sbjct: 215 PVQRQNARTLLKS 227 >4TWL-A nrPDB Length = 246 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 68/254 (26%), Positives = 110/254 (43%), Gaps = 44/254 (17%) Query: 39 PVKWGG------NCQKD-RQSPINIVTTKAKVDKKLG--RFFFSGYDKKQTWTVQNNGHS 89 P WG C K QSPI + + D+ LG R + D + ++N+GH Sbjct: 15 PENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRAVDAR----LRNSGHD 70 Query: 90 VMMLLE-NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKG 148 V++ + N S+S + YQ K++H H SEH ++GE F +E +VHE Sbjct: 71 VLVDFKGNAGSLSINRVE--YQLKRIHFH------SPSEHEMNGERFDLEAQLVHE---- 118 Query: 149 TSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLL 208 +QD + + + F + ++ SN K E++ + + + L + Sbjct: 119 -------SQDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPNQLQID 171 Query: 209 PKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKD 268 Y+RY+GS T P C E + WTV R+ + Q+L Q + E + + Sbjct: 172 DSA-----YYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV---NENAI---N 220 Query: 269 NVRPLQQLGQRTVI 282 N RPLQ R+V Sbjct: 221 NARPLQPTNFRSVF 234 >1KOQ-A nrPDB Length = 223 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 79/278 (28%), Positives = 112/278 (40%), Gaps = 71/278 (25%) Query: 21 SHWCYEVQAESSNYPCLVPVKWGGNCQKDR-------QSPINIVTTKAKVDKKLGRFFFS 73 +HW Y P WG ++ R QSP+NI T V KL + Sbjct: 2 THWGYTGHDS--------PESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVN 50 Query: 74 GYDKKQTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSL 130 K V+NNGH++ + N +++G Y KQ H H +P SE+ + Sbjct: 51 --YKPSMVDVENNGHTIQVNYPEGGNTLTVNG----RTYTLKQFHFH---VP---SENQI 98 Query: 131 DGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE-----GFQPLVE 185 G F ME H VH + E + P VLA L EAG P+ Sbjct: 99 KGRTFPMEAHFVH---------LDENKQP----LVLAVLYEAGKTNGRLSSIWNVMPMTA 145 Query: 186 ALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLH 245 + +P ++T LLPK K Y+R+ GSLTTP C E V W V + + Sbjct: 146 GKVKLNQPFDAST--------LLPKRLK---YYRFAGSLTTPPCTEGVSWLVLKTYDHID 194 Query: 246 REQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIK 283 + Q F++ + +N RP+Q L R VI+ Sbjct: 195 QAQAEKFTRAV---------GSENNRPVQPLNARVVIE 223 >1Y7W-A nrPDB Length = 291 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 61/202 (30%), Positives = 86/202 (42%), Gaps = 38/202 (18%) Query: 96 NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKE 155 N +I GG + Q H H + SEH+++G H+ +E+HIV ++ Sbjct: 111 NLPTIEIGGTTKSFVPIQFHFH-----HFLSEHTINGIHYPLELHIVMQE---------- 155 Query: 156 AQDPED----EIAVLAFLV---EAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD-- 206 QDP D ++AV+ + E G Q +E T ++ Sbjct: 156 -QDPADVATAQLAVIGIMYKYSENGDAFLNSLQTQIEGKIGDGTASYGDTGVSIDNINVK 214 Query: 207 --LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTV 264 LLP K Y Y GSLTTP CDE+V W VF P ++ REQ+ KL+ D Sbjct: 215 TQLLPSSLK---YAGYDGSLTTPGCDERVKWHVFTTPREVTREQM-----KLFVDVTMGA 266 Query: 265 SMKDNV---RPLQQLGQRTVIK 283 +V R +Q LG R V K Sbjct: 267 HAGADVVNNRMIQDLGDREVYK 288 >3Q31-A nrPDB Length = 244 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 61/198 (30%), Positives = 87/198 (43%), Gaps = 40/198 (20%) Query: 97 KASISGGGLPA---PYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNV 153 + +++ G L A Y Q H H SEH ++ EHF ME+H V Sbjct: 76 QVTLTNGSLTANSKTYTLAQFHFHTP------SEHHVNEEHFPMEVHFVF---------- 119 Query: 154 KEAQDPEDEIAVLAF---LVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPK 210 Q E AV+ F L E G V F + + NIP STT + LL Sbjct: 120 ---QTAAKETAVVGFFFQLSEVGDSVPL-FDSVFAPIDNIPDAGTSTTTGQLDFGGLL-- 173 Query: 211 EEKLRH-YFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDN 269 + RH ++Y GSLTTP C E+V+W + EP+ L + Y+K + + +K N Sbjct: 174 DHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQG---------YNKVKKI-IKYN 223 Query: 270 VRPLQQ-LGQRTVIKSGA 286 R Q LGQ +++ A Sbjct: 224 ARYTQNALGQDNLLEVAA 241 >5TT3-A nrPDB Length = 234 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 20/170 (11%) Query: 121 LPYKGSEHSLDGEHFAMEMH-IVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEG 179 + Y+G ++ LD HF M +++ K + S + +D + + VLA E G + N Sbjct: 84 INYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVH-KDAKGRLLVLAIGFEEGKE-NPN 141 Query: 180 FQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFR 239 P++E + + E +L LPK +Y+ + GSLT P C E V W V Sbjct: 142 LDPILEGI------QKKQNFKEVALDAFLPKS---INYYHFNGSLTAPPCTEGVAWFVIE 192 Query: 240 EPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289 EP+++ +Q+ +++ N RP+Q +IKS A R Sbjct: 193 EPLEVSAKQLAEIKKRM--------KNSPNQRPVQPDYNTVIIKSSAETR 234 >3B1B-A nrPDB Length = 377 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 42/146 (28%), Positives = 70/146 (47%), Gaps = 27/146 (18%) Query: 113 QLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEA 172 Q H H + SEH L G+ + +E+HIVH+ + ++ + + + F ++ Sbjct: 161 QFHFHST------SEHLLAGKIYPLELHIVHQ----VTEKLEACKGGCFSVTGILFQLDN 210 Query: 173 GTQVNEGFQPLVEALSNIPKPEMSTTMAESS----LLDLLPKEEKLRHYFRYLGSLTTPT 228 G NE +P+ +N+P E + + + L +LLP + R Y Y GSLTTP Sbjct: 211 GPD-NELLEPI---FANMPSREGTFSNLPAGTTIKLGELLPSD---RDYVTYEGSLTTPP 263 Query: 229 CDEKVVWTVFREPIQLHREQILAFSQ 254 C E ++W V +P Q ++F Q Sbjct: 264 CSEGLLWHVMTQP------QRISFGQ 283 >4UM8-B nrPDB Length = 788 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 12/40 (30%), Positives = 23/40 (57%) Query: 240 EPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQR 279 + +Q+H Q + LYY + + SM D++ +++LG R Sbjct: 119 QTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSR 158 >4UM9-D nrPDB Length = 483 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/40 (30%), Positives = 23/40 (57%) Query: 240 EPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQR 279 + +Q+H Q + LYY + + SM D++ +++LG R Sbjct: 102 QTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSR 141 >5Y34-A nrPDB Length = 596 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 10/28 (35%), Positives = 15/28 (53%) Query: 18 SAESHWCYEVQAESSNYPCLVPVKWGGN 45 A +HW + + NY C+VP W G+ Sbjct: 524 GALAHWIVIEKGKIKNYQCVVPTTWNGS 551 >1Y1X-A nrPDB Length = 191 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 83 VQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIV 142 V +G + + E A++S G+P + LH D + G E + D F H + Sbjct: 36 VDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSG-EITFD--EFKDLHHFI 92 Query: 143 HEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE-GFQPLV 184 +G + D V A L+ +G QV+E FQ L+ Sbjct: 93 LSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALM 135 >2YCH-A nrPDB Length = 377 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Query: 156 AQDPEDEIAVLAFLVEAGTQVN-EGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKL 214 A++P+ VL E+ + V G +PL + + + + +A S LDLL EE Sbjct: 186 AEEPDRVFLVLDIGAESTSLVLLRGDKPLAVRVLTLSGKDFTEAIARSFNLDLLAAEEVK 245 Query: 215 RHYFRYLGSLTTPTCDEKVV 234 R Y G T PT DE+++ Sbjct: 246 RTY----GMATLPTEDEELL 261 >6MSN-A nrPDB Length = 604 Score = 27.3 bits (59), Expect = 9.4, Method: Compositional matrix adjust. Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 130 LDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSN 189 G++FA + ++ G S V A + +LA + ++G + + Q + L + Sbjct: 353 FGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPD 412 Query: 190 IPKPEMSTTMAESSLLDLLPKEEKLR 215 IP+ +STT S +DL +K+R Sbjct: 413 IPEVHLSTT---SVKVDLKRPIDKVR 435 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5JN8-A nrPDB 364 e-101 6G4T-A nrPDB 329 1e-90 3ZNC-A nrPDB 327 4e-90 1Z93-A nrPDB 326 7e-90 4QK3-A nrPDB 326 7e-90 1FLJ-A nrPDB 324 3e-89 4CNR-A nrPDB 320 5e-88 6FAF-A nrPDB 314 2e-86 3D0N-A nrPDB 310 4e-85 4LU3-A nrPDB 300 4e-82 1RJ5-A nrPDB 293 6e-80 1URT-A nrPDB 288 2e-78 2W2J-A nrPDB 277 3e-75 3FE4-A nrPDB 274 3e-74 5LL9-A nrPDB 269 1e-72 5DVX-A nrPDB 266 1e-71 4COQ-A nrPDB 260 8e-70 4X5S-A nrPDB 255 1e-68 4G7A-A nrPDB 246 7e-66 6EKI-A nrPDB 239 2e-63 4XZ5-A nrPDB 236 8e-63 5HPJ-A nrPDB 223 1e-58 4ETQ-X nrPDB 216 1e-56 6B9J-X nrPDB 214 3e-56 4XIW-A nrPDB 212 2e-55 1KOQ-A nrPDB 211 3e-55 4TWL-A nrPDB 202 2e-52 5TT3-A nrPDB 172 2e-43 1Y7W-A nrPDB 170 6e-43 3Q31-A nrPDB 161 4e-40 3B1B-A nrPDB 140 8e-34 Sequences not found previously or not previously below threshold: 4GF1-A nrPDB 32 0.45 4XPS-A nrPDB 31 0.77 1PVG-A nrPDB 30 1.9 5M46-A nrPDB 29 3.8 2BBU-A nrPDB 28 4.9 3QHO-A nrPDB 27 7.4 CONVERGED! >5JN8-A nrPDB Length = 266 Score = 364 bits (933), Expect = e-101, Method: Composition-based stats. Identities = 266/266 (100%), Positives = 266/266 (100%) Query: 19 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK Sbjct: 1 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 60 Query: 79 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME Sbjct: 61 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 120 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT Sbjct: 121 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 180 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY Sbjct: 181 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 240 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 DKEQTVSMKDNVRPLQQLGQRTVIKS Sbjct: 241 DKEQTVSMKDNVRPLQQLGQRTVIKS 266 >6G4T-A nrPDB Length = 274 Score = 329 bits (843), Expect = 1e-90, Method: Composition-based stats. Identities = 91/272 (33%), Positives = 132/272 (48%), Gaps = 16/272 (5%) Query: 18 SAESH-WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD 76 H W Y S++ L P+ Q DRQSPINI++++A L S Y+ Sbjct: 3 MTGHHGWGYGQDDGPSHWHKLYPI-----AQGDRQSPINIISSQAVYSPSLQPLELS-YE 56 Query: 77 KKQTWTVQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGE 133 + ++ NNGHSV + +++ ++GG L PY+ KQ H HW GSEH++DG+ Sbjct: 57 ACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGK 116 Query: 134 HFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKP 193 F E+H+VH K S EA D +AV+ +E G + + L +AL + Sbjct: 117 SFPSELHLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFK 174 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 + + LLP RHY+ Y GSLTTP E V W V REPI + Q+ F Sbjct: 175 GTKAQFSCFNPKSLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFR 231 Query: 254 QKLY-YDKEQTVSMKDNVRPLQQLGQRTVIKS 284 L+ + ++ + M +N RP Q L R V S Sbjct: 232 SLLFTSEDDERIHMVNNFRPPQPLKGRVVKAS 263 >3ZNC-A nrPDB Length = 258 Score = 327 bits (838), Expect = 4e-90, Method: Composition-based stats. Identities = 148/264 (56%), Positives = 190/264 (71%), Gaps = 6/264 (2%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 WCYE+Q E CL P KW G C++++QSPINIVT + KV+ +L F GYD+KQ W Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 60 Query: 83 VQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIV 142 ++NN H+V M L A I GG LPA Y+A QLHLHWS+ GSEHS+DG HFAMEMHIV Sbjct: 61 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 120 Query: 143 HEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAES 202 H+K + D +D+ AVLAF++E G +VN+GFQPLVEAL +I KP ++T+ ES Sbjct: 121 HKKLTSSKE------DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRES 174 Query: 203 SLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQ 262 SL D+LP K+ YFRY GSLTTP CDE V+WTV+++PI++H+ Q L FS+ LYYD++Q Sbjct: 175 SLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQ 234 Query: 263 TVSMKDNVRPLQQLGQRTVIKSGA 286 ++MKDNVRPLQ LG+R V KS A Sbjct: 235 KLNMKDNVRPLQPLGKRQVFKSHA 258 >1Z93-A nrPDB Length = 266 Score = 326 bits (836), Expect = 7e-90, Method: Composition-based stats. Identities = 83/267 (31%), Positives = 126/267 (47%), Gaps = 16/267 (5%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 W Y ++ L P N + + QSPI + T + D L + S YD Sbjct: 4 EWGYASHNGPDHWHELFP-----NAKGENQSPIELHTKDIRHDPSLQPWSVS-YDGGSAK 57 Query: 82 TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 T+ NNG + ++ ++ ++ + GG LP PY+ +Q HLHW GSEH++DG +A E Sbjct: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 +H+VH K + KEA D IAV+ ++ G + E FQ ++AL I Sbjct: 118 LHLVHWNPKYNT--FKEALKQRDGIAVIGIFLKIGHENGE-FQIFLDALDKIKTKGKEAP 174 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 + L P R Y+ Y GS TTP C+E +VW + +EP+ + +Q+ L Sbjct: 175 FTKFDPSSLFPAS---RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSS 231 Query: 259 -DKEQTVSMKDNVRPLQQLGQRTVIKS 284 + E V + N RP Q + R V S Sbjct: 232 AENEPPVPLVSNWRPPQPINNRVVRAS 258 >4QK3-A nrPDB Length = 249 Score = 326 bits (836), Expect = 7e-90, Method: Composition-based stats. Identities = 86/268 (32%), Positives = 125/268 (46%), Gaps = 25/268 (9%) Query: 20 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79 HW Y ++ P+ + +RQSP++I T AK D L S YD+ Sbjct: 2 SHHWGYGKHNGPEHWHKDFPI-----AKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQAT 55 Query: 80 TWTVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 136 + + NNGH+ + ++ KA + GG L Y+ Q H HW L +GSEH++D + +A Sbjct: 56 SLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYA 115 Query: 137 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMS 196 E+H+VH K + +A D +AVL ++ G+ G Q +V+ L +I S Sbjct: 116 AELHLVHWNTK--YGDFGKAVQQPDGLAVLGIFLKVGSAK-PGLQKVVDVLDSIKTKGKS 172 Query: 197 TTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 256 LLP+ Y+ Y GSLTTP E V W V +EPI + EQ+L F + Sbjct: 173 ADFTNFDPRGLLPESL---DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL- 228 Query: 257 YYDKEQTVSMKDNVRPLQQLGQRTVIKS 284 M DN RP Q L R + S Sbjct: 229 ---------MVDNWRPAQPLKNRQIKAS 247 >1FLJ-A nrPDB Length = 260 Score = 324 bits (831), Expect = 3e-89, Method: Composition-based stats. Identities = 81/267 (30%), Positives = 123/267 (46%), Gaps = 16/267 (5%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 W Y ++ L P+ + D QSPI + T + D L + S YD Sbjct: 4 EWGYASHNGPEHWHELYPI-----AKGDNQSPIELHTKDIRHDPSLQPWSVS-YDPGSAK 57 Query: 82 TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 T+ NNG + ++ ++ ++ + GG L PY+ +Q HLHW GSEH++DG +A E Sbjct: 58 TILNNGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 +H+VH K + EA D IAV+ ++ G + E FQ L++AL I Sbjct: 118 LHLVHWNPKYNT--FGEALKQPDGIAVVGIFLKIGREKGE-FQILLDALDKIKTKGKEAP 174 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL-Y 257 L P R Y+ Y GS TTP C+E +VW + +EP+ + +Q+ Sbjct: 175 FNHFDPSCLFPA---CRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFAS 231 Query: 258 YDKEQTVSMKDNVRPLQQLGQRTVIKS 284 + E V + N RP Q + R V S Sbjct: 232 AENEPPVPLVGNWRPPQPIKGRVVRAS 258 >4CNR-A nrPDB Length = 262 Score = 320 bits (820), Expect = 5e-88, Method: Composition-based stats. Identities = 80/267 (29%), Positives = 119/267 (44%), Gaps = 16/267 (5%) Query: 20 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79 HW Y+ ++ P+ G +RQSP++I T D L Y + Sbjct: 4 SHHWGYDKHNGPEHWHKDFPIANG-----ERQSPVDIDTDAVVQDPALKPLALD-YGEAT 57 Query: 80 TWTVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 136 + + N+GHS + ++ KA + G L Y+ Q H HW +GSEH++D + +A Sbjct: 58 SRRMVNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYA 117 Query: 137 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMS 196 E+H+VH K + A D +AV+ ++ G N Q +++AL +I S Sbjct: 118 AELHLVHWNTK--YGDFGTAAQEPDGLAVVGVFLKVGD-ANPALQKVLDALDSIKTKGKS 174 Query: 197 TTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK- 255 T LLP + Y+ Y GSLTTP E V W V +EPI + +Q+L F Sbjct: 175 TDFPNFDPGSLLP---NVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLN 231 Query: 256 LYYDKEQTVSMKDNVRPLQQLGQRTVI 282 + E M N RP Q L R V Sbjct: 232 FNAEGEPEELMLANWRPAQPLKNRQVR 258 >6FAF-A nrPDB Length = 261 Score = 314 bits (805), Expect = 2e-86, Method: Composition-based stats. Identities = 80/271 (29%), Positives = 121/271 (44%), Gaps = 15/271 (5%) Query: 18 SAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDK 77 A W Y+ + + L P+ G N QSP++I T++ K D L S Y+ Sbjct: 1 MASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNP 54 Query: 78 KQTWTVQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEH 134 + N GHS + +N++ + GG Y+ Q H HW GSEH++DG Sbjct: 55 ATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVK 114 Query: 135 FAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPE 194 ++ E+H+ H S ++ EA D +AV+ L++ G + N Q +++AL I Sbjct: 115 YSAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKG 172 Query: 195 MSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQ 254 LLP ++ Y GSLT P E V W + +E I + EQ+ F Sbjct: 173 KRAPFTNFDPSTLLPSSL---DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRS 229 Query: 255 KL-YYDKEQTVSMKDNVRPLQQLGQRTVIKS 284 L + + V M+ N RP Q L RTV S Sbjct: 230 LLSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260 >3D0N-A nrPDB Length = 264 Score = 310 bits (795), Expect = 4e-85, Method: Composition-based stats. Identities = 84/266 (31%), Positives = 119/266 (44%), Gaps = 15/266 (5%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82 W Y ++ P+ G D+QSPI I T + K D L YD Sbjct: 8 WGYREHNGPIHWKEFFPIADG-----DQQSPIEIKTKEVKYDSSLRPLSI-KYDPSSAKI 61 Query: 83 VQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + N+GHS + + NK+ + GG L Y+ +Q+HLHW GSEH +DG +A E+ Sbjct: 62 ISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAEL 121 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH + EA D +AVL ++ G + N Q + + L +I + T Sbjct: 122 HVVHWNSDKY-PSFVEAAHEPDGLAVLGVFLQIG-EPNSQLQKITDTLDSIKEKGKQTRF 179 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL-YY 258 LL LLP Y+ Y GSLT P E V W V ++PI + +Q+ F L Sbjct: 180 TNFDLLSLLPPSW---DYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTA 236 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKS 284 + E + N RP Q L R V S Sbjct: 237 EGEAAAFLVSNHRPPQPLKGRKVRAS 262 >4LU3-A nrPDB Length = 279 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 95/272 (34%), Positives = 133/272 (48%), Gaps = 14/272 (5%) Query: 17 ASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD 76 A HW YE ++P P C + QSPI+I T D L GYD Sbjct: 1 ADGGQHWTYEGPHGQDHWPASYPE-----CGNNAQSPIDIQTDSVTFDPDLPALQPHGYD 55 Query: 77 KKQT--WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKG-SEHSLDGE 133 + T + NNGH+V + L +++ GGLP Y A QLHLHW G SEH ++ E Sbjct: 56 QPGTEPLDLHNNGHTVQLSLP--STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSE 113 Query: 134 HFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKP 193 E+HIVH ++ EA + +AVL L+E G N ++ ++ L + Sbjct: 114 ATFAELHIVHYDSDSY-DSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHK 172 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 + T++ +L +LLPK +L YFRY GSLTTP C + V+WTVF Q+ EQ+ Sbjct: 173 DQKTSVPPFNLRELLPK--QLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQ 230 Query: 254 QKLYYDKEQTVS-MKDNVRPLQQLGQRTVIKS 284 L+ +E+ + N R LQ L QR V S Sbjct: 231 GTLFSTEEEPSKLLVQNYRALQPLNQRMVFAS 262 >1RJ5-A nrPDB Length = 261 Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats. Identities = 91/270 (33%), Positives = 132/270 (48%), Gaps = 14/270 (5%) Query: 19 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDK- 77 HW YE ++P P C D QSPINI T D L GYD+ Sbjct: 1 GGHHWTYEGPHGQDHWPTSYPE-----CGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQL 55 Query: 78 -KQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPY-KGSEHSLDGEHF 135 + + NNGH+V + L ++ GGLP Y A QLHLHW +GSEH ++ E Sbjct: 56 GTEPLDLHNNGHTVQLSLP--PTLHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEAT 113 Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195 A E+H+VH + S ++ EA +AVL L+E G N + ++ L I + Sbjct: 114 AAELHVVHYDSQSYS-SLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQ 172 Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255 T++ S+ +L P+ +L +FRY GSLTTP C + V+WTVF Q+ Q+ + Sbjct: 173 KTSVPPFSVRELFPQ--QLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQET 230 Query: 256 LYY-DKEQTVSMKDNVRPLQQLGQRTVIKS 284 L +++ + + N R Q L QRT+ S Sbjct: 231 LSSTEEDPSEPLVQNYRVPQPLNQRTIFAS 260 >1URT-A nrPDB Length = 248 Score = 288 bits (736), Expect = 2e-78, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 117/244 (47%), Gaps = 10/244 (4%) Query: 45 NCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLEN---KASIS 101 + + RQSPINI + D +L S YD + N GH+ + ++ + IS Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAPLRVS-YDAASCRYLWNTGHAFQVEFDDSCEDSGIS 59 Query: 102 GGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPED 161 GG L Y+ KQ H HW GSEH++DG + E+H+VH N K+A E+ Sbjct: 60 GGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKY-ENYKKASVGEN 118 Query: 162 EIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYL 221 +AV+ ++ G ++ Q LV+ L + + M + L+P R Y+ Y Sbjct: 119 GLAVIGVFLKLGAH-HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPA---CRDYWTYP 174 Query: 222 GSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDK-EQTVSMKDNVRPLQQLGQRT 280 GSLTTP E V W V + P+++ Q+ F L+ + E+ M +N RPLQ L R Sbjct: 175 GSLTTPPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRK 234 Query: 281 VIKS 284 + S Sbjct: 235 LRSS 238 >2W2J-A nrPDB Length = 291 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 76/260 (29%), Positives = 130/260 (50%), Gaps = 17/260 (6%) Query: 34 YPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFS-GYDKKQTWTVQNNGHSVMM 92 + + P + + QSPIN+ + +A+ D L S Y + V N+GH++ + Sbjct: 38 WGLVFP-----DANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQV 92 Query: 93 LLENKASISGGGLP--APYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTS 150 +L++K+ +SGG LP ++ ++ HW +GSEH+++ + F ME+H++H Sbjct: 93 ILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNST-LF 151 Query: 151 RNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPK 210 ++ EA IA++A V+ G + + G + + E L +I S T+ + LLP Sbjct: 152 GSIDEAVGKPHGIAIIALFVQIGKE-HVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLP- 209 Query: 211 EEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVS----- 265 + LR Y+ Y GSLT P C E V W +FR P+ + + QI F + + K + Sbjct: 210 DPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDG 269 Query: 266 -MKDNVRPLQQLGQRTVIKS 284 + DN RP Q L R + + Sbjct: 270 ILGDNFRPTQPLSDRVIRAA 289 >3FE4-A nrPDB Length = 278 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 91/276 (32%), Positives = 140/276 (50%), Gaps = 22/276 (7%) Query: 21 SHWCY-EVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD-KK 78 S W Y E + +++P P C RQSPIN+ TK + + L +GY+ + Sbjct: 2 SDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA 56 Query: 79 QTWTVQNNGHSVMMLLEN--KASISGGGLPAPYQAKQLHLHWS--DLPYKGSEHSLDGEH 134 + + NNGH+V + L + + +++ G + Y A+Q+H HW GSEH++DG Sbjct: 57 GEFPMVNNGHTVQISLPSTMRMTVADGTV---YIAQQMHFHWGGASSEISGSEHTVDGIR 113 Query: 135 FAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGT-QVNEGFQPLVEALSNIPKP 193 +E+HIVH K S ++ AQD D +AVLA VE N + + L+NI P Sbjct: 114 HVIEIHIVHYNSKYKSYDI--AQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYP 171 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 TT+ + D+LP+ L+HY+ Y GSLTTP C E V W V + ++L R Q+ Sbjct: 172 GQRTTLTGLDVQDMLPR--NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLE 229 Query: 254 QKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289 L + +T+ ++ R Q L R V +S P + Sbjct: 230 NSLLDHRNKTIH--NDYRRTQPLNHRVV-ESNFPNQ 262 >5LL9-A nrPDB Length = 263 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 91/270 (33%), Positives = 137/270 (50%), Gaps = 17/270 (6%) Query: 21 SHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYD--KK 78 S W Y +++ P +C QSPI++ + + D L F GY+ Sbjct: 2 SKWTYFGPDGENSWSKKYP-----SCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSAN 56 Query: 79 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPY-KGSEHSLDGEHFAM 137 + + + NNGHSV + L + I G L + Y A QLHLHW + GSEH++ G+HFA Sbjct: 57 KQFLLTNNGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAA 114 Query: 138 EMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMST 197 E+HIVH + A + + +AVLA L+E G+ N + + L ++ Sbjct: 115 ELHIVHYNSD-LYPDASTASNKSEGLAVLAVLIEMGS-FNPSYDKIFSHLQHVKYKGQEA 172 Query: 198 TMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLY 257 + ++ +LLP E+ Y+RY GSLTTP C+ V+WTVFR P+Q+ +EQ+LA LY Sbjct: 173 FVPGFNIEELLP--ERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALY 230 Query: 258 ---YDKEQTVSMKDNVRPLQQLGQRTVIKS 284 D M +N R +Q+ +R V S Sbjct: 231 CTHMDDPSPREMINNFRQVQKFDERLVYTS 260 >5DVX-A nrPDB Length = 260 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 17/265 (6%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ-- 79 HW Y +P + P C QSP++I A L SG+ Sbjct: 1 HWRYG---GDPPWPRVSPA-----CAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLP 52 Query: 80 TWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 ++NNGHSV + L + G Y+A QLHLHW GSEH+++G F E+ Sbjct: 53 ELRLRNNGHSVQLTLPPGLEMKLGP-GREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEI 111 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH K V EA +AVLA +E G + N ++ L+ L I + T + Sbjct: 112 HVVHLSTK--YARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQV 169 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYD 259 + LLP + YF+Y GSLTTP C + V+WTVF + + L +Q+ S L+ Sbjct: 170 PGLDISALLPSD--FSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGP 227 Query: 260 KEQTVSMKDNVRPLQQLGQRTVIKS 284 + + + N R Q L R + S Sbjct: 228 GDSRLQL--NFRATQPLNGRVIEAS 250 >4COQ-A nrPDB Length = 247 Score = 260 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 77/263 (29%), Positives = 113/263 (42%), Gaps = 41/263 (15%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQ-KDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQT 80 HW Y ++ L P C+ QSPI+I + A V L S Y Sbjct: 25 HWGYSGSIGPEHWGDLSPEYL--MCKIGKNQSPIDINSADA-VKACLAP--VSVYYVSDA 79 Query: 81 WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMH 140 V NNGH++ +++ + + G + KQ H H SEH+++G+H+ E H Sbjct: 80 KYVVNNGHTIKVVMGGRGYVVVDG--KRFYLKQFHFH------APSEHTVNGKHYPFEAH 131 Query: 141 IVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMA 200 VH D I VL + G + N + + + P + A Sbjct: 132 FVH-------------LDKNGNITVLGVFFKVGKE-NPELEKVWRVMPEEP-GQKRHLTA 176 Query: 201 ESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDK 260 LLP+ R Y+RY GSLTTP C E V W VF+EP+++ REQ+ F + + + Sbjct: 177 RIDPEKLLPEN---RDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGF-- 231 Query: 261 EQTVSMKDNVRPLQQLGQRTVIK 283 DN RP+Q L R V+K Sbjct: 232 -------DNNRPVQPLNARKVMK 247 >4X5S-A nrPDB Length = 232 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 73/272 (26%), Positives = 123/272 (45%), Gaps = 41/272 (15%) Query: 15 PSASAE-SHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFS 73 S AE HW YE + N+ L P + C QSP++I + KV KL + + Sbjct: 1 GSHMAEVHHWSYEGENGPENWAKLNPEYFW--CNLKNQSPVDI-SDNYKVHAKLEKLHIN 57 Query: 74 GYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGE 133 Y+K + NNGH++ + + ++ G Y KQ H H SEH+++G+ Sbjct: 58 -YNKAVNPEIVNNGHTIQVNVLEDFKLNIKG--KEYHLKQFHFH------APSEHTVNGK 108 Query: 134 HFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKP 193 ++ +EMH+VH +D + IAV+ + G N + + + + + Sbjct: 109 YYPLEMHLVH-------------KDKDGNIAVIGVFFKEGK-ANPELDKVFK--NALKEE 152 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 ++ LLP +++Y+ Y GSLTTP C E V+W V ++PI ++QI F Sbjct: 153 GSKVFDGSININALLPP---VKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFK 209 Query: 254 QKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSG 285 + +N RP Q + R +++S Sbjct: 210 S---------IMKHNNNRPTQPINSRYILESN 232 >4G7A-A nrPDB Length = 248 Score = 246 bits (629), Expect = 7e-66, Method: Composition-based stats. Identities = 69/270 (25%), Positives = 120/270 (44%), Gaps = 40/270 (14%) Query: 14 RPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFS 73 R S E W YE + ++ L P + C+ QSPINI K KV L + Sbjct: 17 RGSHMLEHEWSYEGEKGPEHWAQLKPEFFW--CKLKNQSPINI-DKKYKVKANLPKLNLY 73 Query: 74 GYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGE 133 Y + V NNGH++ + ++ +++ L YQ KQ H H SEH+++ + Sbjct: 74 -YKTAKESEVVNNGHTIQINIKEDNTLNY--LGEKYQLKQFHFH------TPSEHTIEKK 124 Query: 134 HFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKP 193 + +E+H VH + + +I V+ + + G N+ ++ + Sbjct: 125 SYPLEIHFVH-------------KTEDGKILVVGVMAKLGKT-NKELDKILNVAPA--EE 168 Query: 194 EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFS 253 +L +L+PK+++ Y Y GSLTTP C E V W V ++PI + ++Q+ Sbjct: 169 GEKILDKNLNLNNLIPKDKR---YMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLK 225 Query: 254 QKLYYDKEQTVSMKDNVRPLQQLGQRTVIK 283 + + N RP+Q++ R +I+ Sbjct: 226 SVM---------VNPNNRPVQEINSRWIIE 246 >6EKI-A nrPDB Length = 226 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 71/265 (26%), Positives = 118/265 (44%), Gaps = 46/265 (17%) Query: 21 SHWCYEVQAESSNYPCLVPVKWGGNCQ-KDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79 HW Y + ++ L C+ QSP++I V+ +L + + Sbjct: 4 GHWSYHGETGPQHWGDLKNEYI--MCKIGKNQSPVDISR---IVEAELEKIKIN--YSSG 56 Query: 80 TWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 ++ NNGH++ + E + I G+ ++ KQ H H SEH++ G+ + E Sbjct: 57 GSSITNNGHTIKVSYEPGSYIIVDGI--RFELKQFHFH------APSEHTIKGKSYPFEA 108 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H VH D + +AV+ + + G N + + E N+P+ + + Sbjct: 109 HFVH-------------ADKDGNLAVIGVIFKEGK-KNPIIEKIWE---NLPEAGKTIKL 151 Query: 200 AE-SSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 A + DLLPK++K Y+RY GSLTTP C E V W V E ++L +EQI F + + Sbjct: 152 AHKINAYDLLPKKKK---YYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMG- 207 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIK 283 D RP+Q L R +++ Sbjct: 208 --------GDTNRPVQPLNARMIME 224 >4XZ5-A nrPDB Length = 233 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 75/265 (28%), Positives = 113/265 (42%), Gaps = 40/265 (15%) Query: 21 SHWCYEVQAESSNYPCLVPVKWGGNCQ-KDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79 HW Y + + L P C+ QSPIN+ A L F Y ++ Sbjct: 2 PHWGYFGEEGPQYWGELAPEF--STCKTGKNQSPINLKPQTAVGTTSLPGFDV--YYRET 57 Query: 80 TWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 + NNGH++ + + + I G Y+ Q H H SEH DG ++ MEM Sbjct: 58 ALKLINNGHTLQVNIPLGSYIKING--HRYELLQYHFH------TPSEHQRDGFNYPMEM 109 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H+VH +D + +AV+A L + G + NE L+ L K + Sbjct: 110 HLVH-------------KDGDGNLAVIAILFQEGEE-NETLAKLMSFLPQTLKKQEIHES 155 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYD 259 + P ++K +++Y GSLTTP C E V W VF++PIQ Q+ + L Sbjct: 156 VKIHPAKFFPADKK---FYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYL--- 209 Query: 260 KEQTVSMKDNVRPLQQLGQRTVIKS 284 N RP+Q+ RT++KS Sbjct: 210 -------GSNARPVQRQNARTLLKS 227 >5HPJ-A nrPDB Length = 217 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 69/263 (26%), Positives = 111/263 (42%), Gaps = 47/263 (17%) Query: 22 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81 W Y + + ++ + Q+PI+I T +L + Q Sbjct: 1 EWSYTGEHGTEHWGDSF----ATCAEGVNQTPIDINQTT---QAELAPLHLD--YEGQVT 51 Query: 82 TVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHI 141 + NNGH++ L K +++ G ++ KQ H H SE+ L G+ + +E H Sbjct: 52 ELVNNGHTIQANLTGKNTLTVDG--KTFELKQFHFH------TPSENYLKGKQYPLEAHF 103 Query: 142 VHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAE 201 VH +K E+AV+A + + G + N L L++IP + + E Sbjct: 104 VHATDK-------------GELAVVAVMFDFGPRSN---NELTTLLASIPSKGQTVELKE 147 Query: 202 -SSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDK 260 + DLLP++ R Y+R+ GSLTTP C E V W V +EP + Q Sbjct: 148 ALNPADLLPRD---REYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQ------- 197 Query: 261 EQTVSMKDNVRPLQQLGQRTVIK 283 M +N RPLQ L R +++ Sbjct: 198 ---AVMGNNARPLQPLNARLILE 217 >4ETQ-X nrPDB Length = 269 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 68/232 (29%), Positives = 109/232 (46%), Gaps = 11/232 (4%) Query: 52 SPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQA 111 SPINI T KA + +L Y++ + T+QN G V + + ISGG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIH-YNESKPTTIQNTGKLVRINFKG-GYISGGFLPNEYVL 63 Query: 112 KQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171 LH++W GS H +D ++ E+++VH +K S + +EA+ +D + +++ ++ Sbjct: 64 SSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYS-SYEEAKKHDDGLIIISIFLQ 122 Query: 172 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD-LLPKEEKLRHYFRYLGSLTTPTCD 230 N FQ +V L +I S LD LLP + YF YLG+ + D Sbjct: 123 VLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKL---DYFTYLGTTINHSAD 179 Query: 231 EKVVWTVFREPIQLHREQILAFSQK--LYYDKEQTVSMKDNVRPLQQLGQRT 280 VW +F PI +H +Q+ F L + + + +N R +L T Sbjct: 180 --AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLNDDT 229 >6B9J-X nrPDB Length = 241 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 68/232 (29%), Positives = 109/232 (46%), Gaps = 11/232 (4%) Query: 52 SPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQA 111 SPINI T KA + +L Y++ + T+QN G V + + ISGG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIH-YNESKPTTIQNTGKLVRINFKG-GYISGGFLPNEYVL 63 Query: 112 KQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171 LH++W GS H +D ++ E+++VH +K S + +EA+ +D + +++ ++ Sbjct: 64 SSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYS-SYEEAKKHDDGLIIISIFLQ 122 Query: 172 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD-LLPKEEKLRHYFRYLGSLTTPTCD 230 N FQ +V L +I S LD LLP + YF YLG+ + D Sbjct: 123 VLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKL---DYFTYLGTTINHSAD 179 Query: 231 EKVVWTVFREPIQLHREQILAFSQK--LYYDKEQTVSMKDNVRPLQQLGQRT 280 VW +F PI +H +Q+ F L + + + +N R +L T Sbjct: 180 --AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLNDDT 229 >4XIW-A nrPDB Length = 239 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 80/265 (30%), Positives = 114/265 (43%), Gaps = 39/265 (14%) Query: 23 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINI--VTTKAKVDKKLGRFFFSGYDKKQT 80 W Y A + G RQSPINI T+ KVD ++G F F Y + Sbjct: 4 WNYGEVAGPPTWK-------GVCATGKRQSPINIPLNTSAPKVDAEMGEFDF-AYGSFEK 55 Query: 81 WTVQNNGH-SVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 V N GH ++ + G + + Q H H SEH++DG +AME Sbjct: 56 CDVLNTGHGTMQVNFPAGNLAFIGNM--ELELLQFHFH------APSEHAMDGRRYAMEA 107 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQ-VNEGFQPLVEALSNIPKPEMSTT 198 H+VH+ + +AVL ++E G N +E +P + + Sbjct: 108 HLVHKNKST------------GNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP 155 Query: 199 MAESSLLDLLPKEEK--LRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 256 + + LLPK+ K R + Y GSLTTP C E V W VF +PI++ QIL F + + Sbjct: 156 -KGINPVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFV 214 Query: 257 YYDKEQTVSMKDNVRPLQQLGQRTV 281 +K + N RPLQ L R V Sbjct: 215 GDNK----TYATNTRPLQLLNSRLV 235 >1KOQ-A nrPDB Length = 223 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 72/264 (27%), Positives = 103/264 (39%), Gaps = 43/264 (16%) Query: 21 SHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQT 80 +HW Y ++ L ++ QSP+NI T V KL + K Sbjct: 2 THWGYTGHDSPESWGNLS-EEFRLCSTGKNQSPVNITET---VSGKLPAIKVN--YKPSM 55 Query: 81 WTVQNNGHSVMMLLE-NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139 V+NNGH++ + +++ G Y KQ H H SE+ + G F ME Sbjct: 56 VDVENNGHTIQVNYPEGGNTLTVNG--RTYTLKQFHFH------VPSENQIKGRTFPMEA 107 Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199 H VH + E + P VLA L EAG N + + Sbjct: 108 HFVH---------LDENKQP----LVLAVLYEAGKT-NGRLSSIWNVMP--MTAGKVKLN 151 Query: 200 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYD 259 LLPK K Y+R+ GSLTTP C E V W V + + + Q F++ + + Sbjct: 152 QPFDASTLLPKRLK---YYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSE 208 Query: 260 KEQTVSMKDNVRPLQQLGQRTVIK 283 N RP+Q L R VI+ Sbjct: 209 ---------NNRPVQPLNARVVIE 223 >4TWL-A nrPDB Length = 246 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 66/266 (24%), Positives = 112/266 (42%), Gaps = 36/266 (13%) Query: 20 ESHWCY--EVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDK 77 E + Y N+ L P W + QSPI + + D+ LG+ + + Sbjct: 2 EDEFSYIDGNPNGPENWGNLKPE-WETCGKGMEQSPIQLRDNRVIFDQTLGKLRRN--YR 58 Query: 78 KQTWTVQNNGHSVMMLLE-NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 136 ++N+GH V++ + N S+S + YQ K++H H SEH ++GE F Sbjct: 59 AVDARLRNSGHDVLVDFKGNAGSLSINRV--EYQLKRIHFH------SPSEHEMNGERFD 110 Query: 137 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMS 196 +E +VH E+QD + + + F + ++ SN K E++ Sbjct: 111 LEAQLVH-----------ESQDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEIN 159 Query: 197 TTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 256 + + + L + Y+RY+GS T P C E + WTV R+ + Q+L Q + Sbjct: 160 AGVVDPNQLQIDDSA-----YYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV 214 Query: 257 YYDKEQTVSMKDNVRPLQQLGQRTVI 282 + +N RPLQ R+V Sbjct: 215 NEN------AINNARPLQPTNFRSVF 234 >5TT3-A nrPDB Length = 234 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 62/271 (22%), Positives = 99/271 (36%), Gaps = 46/271 (16%) Query: 21 SHWCYE-VQAESSNYPCLVPVKWGGNCQ-KDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78 + W Y+ + + L K C+ QSPINI + F Y Sbjct: 8 TKWDYKNKENGPHRWDKLH--KDFEVCKSGKSQSPINIE--HYYHTQDKADLQF-KYAAS 62 Query: 79 QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138 + V H++ E I+ G Y +H H E ++ + + Sbjct: 63 KPKAVFFTHHTLKASFEPTNHINYRG--HDYVLDNVHFHAPM------EFLINNKTRPLS 114 Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198 H VH +D + + VLA E G + N P++E + + Sbjct: 115 AHFVH-------------KDAKGRLLVLAIGFEEGKE-NPNLDPILEGI------QKKQN 154 Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258 E +L LPK +Y+ + GSLT P C E V W V EP+++ +Q+ +++ Sbjct: 155 FKEVALDAFLPKS---INYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRM-- 209 Query: 259 DKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289 N RP+Q +IKS A R Sbjct: 210 ------KNSPNQRPVQPDYNTVIIKSSAETR 234 >1Y7W-A nrPDB Length = 291 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 72/298 (24%), Positives = 108/298 (36%), Gaps = 43/298 (14%) Query: 13 ARPSASAESHWCYEVQAESSNYPCL--VPVKWGGNCQKDRQSPINIVTTKA--------K 62 R S + Y+ ++P L C QSPI+I T + Sbjct: 11 GRGSEEPNPNDGYDYMQHGFDWPGLQEGGTTKYPACSGSNQSPIDINTNQLMEPSSRSGT 70 Query: 63 VDKKLGRFFFSGYDKKQTWTVQNNG----HSVMMLLE----NKASISGGGLPAPYQAKQL 114 L G + T+ N + + + N +I GG + Q Sbjct: 71 SAVSLNGLNVDG-AQADGITLTNAKVDLEQGMKVTFDQPAANLPTIEIGGTTKSFVPIQF 129 Query: 115 HLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLV---E 171 H H + SEH+++G H+ +E+HIV +++ A ++AV+ + E Sbjct: 130 HFH-----HFLSEHTINGIHYPLELHIVMQEQDP-------ADVATAQLAVIGIMYKYSE 177 Query: 172 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLD----LLPKEEKLRHYFRYLGSLTTP 227 G Q +E T ++ LLP K Y Y GSLTTP Sbjct: 178 NGDAFLNSLQTQIEGKIGDGTASYGDTGVSIDNINVKTQLLPSSLK---YAGYDGSLTTP 234 Query: 228 TCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSG 285 CDE+V W VF P ++ REQ+ F + N R +Q LG R V K Sbjct: 235 GCDERVKWHVFTTPREVTREQMKLFVDVTMGAHAGADVV--NNRMIQDLGDREVYKYN 290 >3Q31-A nrPDB Length = 244 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 69/281 (24%), Positives = 102/281 (36%), Gaps = 45/281 (16%) Query: 13 ARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKK-LGRFF 71 A + + Y N+ L + QSPI I + + Sbjct: 1 AAGGLDDANKFNYTGLGGPLNWYGLD-EANEACAKGKHQSPIVIDSAAIDYAASGSLKLD 59 Query: 72 FSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLD 131 D + ++N G + + L N + + Y Q H H SEH ++ Sbjct: 60 LPLADGSK---LENLGFGLQVTLTNGSLTAN---SKTYTLAQFHFH------TPSEHHVN 107 Query: 132 GEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLV---EAGTQVNEGFQPLVEALS 188 EHF ME+H V Q E AV+ F E G V F + + Sbjct: 108 EEHFPMEVHFVF-------------QTAAKETAVVGFFFQLSEVGDSV-PLFDSVFAPID 153 Query: 189 NIPKPEMSTTMAESSLLDLLPKEEKLRH-YFRYLGSLTTPTCDEKVVWTVFREPIQLHRE 247 NIP STT + LL + RH ++Y GSLTTP C E+V+W + EP+ L + Sbjct: 154 NIPDAGTSTTTGQLDFGGLL--DHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQ 211 Query: 248 QILAFSQKLYYDKEQTVSMKDNVRPLQQ-LGQRTVIKSGAP 287 + + Y N R Q LGQ +++ A Sbjct: 212 GYNKVKKIIKY----------NARYTQNALGQDNLLEVAAQ 242 >3B1B-A nrPDB Length = 377 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 59/289 (20%), Positives = 104/289 (35%), Gaps = 56/289 (19%) Query: 19 AESHWCYEVQAESSNYPCLVPVKWGGNCQKDR-QSPINIVTTKA---KVDKKLGRFFFSG 74 + HW N+ C+ R QSPIN+ + K K Sbjct: 36 SGDHWD-HGLNG-ENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQTQW 93 Query: 75 YDK-----KQTWTVQNNGHSVMM----LLENKASISGGGLPA------------------ 107 + V NNGH++ + A+I+ + Sbjct: 94 SYPDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAAD 153 Query: 108 --PYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAV 165 Q H H + SEH L G+ + +E+HIVH+ + ++ + + Sbjct: 154 RVTAVPTQFHFHST------SEHLLAGKIYPLELHIVHQ----VTEKLEACKGGCFSVTG 203 Query: 166 LAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESS----LLDLLPKEEKLRHYFRYL 221 + F ++ G NE +P+ +N+P E + + + L +LLP + R Y Y Sbjct: 204 ILFQLDNGPD-NELLEPI---FANMPSREGTFSNLPAGTTIKLGELLPSD---RDYVTYE 256 Query: 222 GSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNV 270 GSLTTP C E ++W V +P ++ Q + + + + + Sbjct: 257 GSLTTPPCSEGLLWHVMTQPQRISFGQWNRYRLAVGLKECNSTETAADA 305 >4GF1-A nrPDB Length = 460 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 17/44 (38%) Query: 131 DGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGT 174 +G+ F + H V K + A+D ++ + E G Sbjct: 56 EGKSFPLREHFVFAKGGKEPSLIIHAEDYASHLSSVEVYYELGK 99 >4XPS-A nrPDB Length = 720 Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 44/139 (31%), Gaps = 23/139 (16%) Query: 14 RPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFS 73 R S A SH A+++N+ + P W K K Sbjct: 17 RGSHMASSH------AQTANWTEIYPGVWKATVGKPE------SYDLLKAAGAQPNKDAL 64 Query: 74 GYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGE 133 +K ++ N G S+ + K + L Q L++ + +G Sbjct: 65 SKTEKVSFPFANGGVSLEVS-GGKTYLRF-PLQKEEQLYGFGLNFQTVHQRGK------- 115 Query: 134 HFAMEMHIVHEKEKGTSRN 152 +E+H+ H K + R Sbjct: 116 --ILELHVDHYGGKDSGRT 132 >1PVG-A nrPDB Length = 418 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Query: 54 INIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISG 102 +N K + D + R + + ++ T V+N+G + + + NK +I Sbjct: 74 VNAADNKVR-DPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYI 121 >5M46-A nrPDB Length = 440 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 74 GYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQ 113 Y ++ +GHSV + P PY+ Q Sbjct: 140 AYHGCTVGSMAFSGHSVQADAAKADGLILLPYPDPYRPYQ 179 >2BBU-A nrPDB Length = 164 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%) Query: 189 NIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLG 222 ++P E S+ + E LP R Y+ Y G Sbjct: 116 SLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSG 149 >3QHO-A nrPDB Length = 458 Score = 27.4 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 20/64 (31%), Gaps = 15/64 (23%) Query: 15 PSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSG 74 P + W Y + WGGN + P+N+ K + F Sbjct: 259 PKTDSSYKWGYNA------W-------WGGNLMAVKDYPVNLPRNKLVYSPHV--FGPDV 303 Query: 75 YDKK 78 Y++ Sbjct: 304 YNQP 307 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.128 0.400 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,277,024 Number of Sequences: 36641 Number of extensions: 480360 Number of successful extensions: 1500 Number of sequences better than 10.0: 37 Number of HSP's better than 10.0 without gapping: 71 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1185 Number of HSP's gapped (non-prelim): 81 length of query: 312 length of database: 10,336,785 effective HSP length: 97 effective length of query: 215 effective length of database: 6,782,608 effective search space: 1458260720 effective search space used: 1458260720 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)