BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P22543 (875 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5DFZ-C nrPDB 1788 0.0 6I3U-A nrPDB 422 e-118 2X6F-A nrPDB 415 e-116 5DXT-A nrPDB 210 2e-54 4ANW-A nrPDB 206 4e-53 4AJW-A nrPDB 203 2e-52 4BFR-A nrPDB 190 2e-48 5C4G-E nrPDB 118 1e-26 4D0L-A nrPDB 118 1e-26 6GL3-A nrPDB 117 2e-26 6FTQ-A nrPDB 37 0.039 6NHI-A nrPDB 32 1.3 1WZO-A nrPDB 30 6.7 2WSI-A nrPDB 29 8.8 >5DFZ-C nrPDB Length = 875 Score = 1788 bits (4630), Expect = 0.0, Method: Compositional matrix adjust. Identities = 873/875 (99%), Positives = 874/875 (99%) Query: 1 MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL 60 M+LNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL Sbjct: 1 MALNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL 60 Query: 61 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI 120 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI Sbjct: 61 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI 120 Query: 121 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL 180 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL Sbjct: 121 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL 180 Query: 181 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST 240 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST Sbjct: 181 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST 240 Query: 241 DLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD 300 LREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD Sbjct: 241 GLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD 300 Query: 301 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL 360 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL Sbjct: 301 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL 360 Query: 361 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS 420 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS Sbjct: 361 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS 420 Query: 421 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL 480 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL Sbjct: 421 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL 480 Query: 481 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV 540 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV Sbjct: 481 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV 540 Query: 541 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF 600 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF Sbjct: 541 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF 600 Query: 601 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI 660 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI Sbjct: 601 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI 660 Query: 661 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY 720 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY Sbjct: 661 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY 720 Query: 721 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES 780 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES Sbjct: 721 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES 780 Query: 781 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE 840 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE Sbjct: 781 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE 840 Query: 841 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT 875 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT Sbjct: 841 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT 875 >6I3U-A nrPDB Length = 615 Score = 422 bits (1084), Expect = e-118, Method: Compositional matrix adjust. Identities = 250/616 (40%), Positives = 371/616 (60%), Gaps = 32/616 (5%) Query: 280 KYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKK 339 K+ +L R+ ++ D +KP+ RD LN I++YPP +LT E+ +WK+RYYL N +K Sbjct: 4 KHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEK 63 Query: 340 ALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKAS 399 ALTK L+ N E + LEL+ W +D++D+LELL S + N +VR YAV RL++A Sbjct: 64 ALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQAD 123 Query: 400 DKELELYLLQLVEAVCFENLSTFSD-----KSNSEFTIVDAVSSQKLSG----DSMLLST 450 D++L +YLLQLV+A+ +EN + K +S+ ++ + VS+ ++ S ++++ Sbjct: 124 DEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITS 183 Query: 451 SHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKP 510 + S E E+L L FLI RA N L ++ YWY+ E ED+ Sbjct: 184 PLPSVSSPPPASKTKEVPDGENLE---QDLCTFLISRACKNSTLANYLYWYVIVECEDQD 240 Query: 511 -----------YLDQILSSFWSRLDKKS------RNILNDQVRLINVLRECCETIKRLKD 553 YL+ ++ F L K R++L Q ++ L + ++R Sbjct: 241 TQQRDPKTHEMYLN-VMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESG 299 Query: 554 TTAKKMELLVHLL-ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFK 612 KK E L LL + + L V I LPL+P V I + PET+ + KS+ P ++ FK Sbjct: 300 NRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLAKSANMPAQLFFK 359 Query: 613 TTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEF 672 T Y ++FK GDDLRQDQL++QIISLM++LL+ EN+DLKLTPYK+LAT + G +++ Sbjct: 360 TEDGGKYPVLFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFLQW 419 Query: 673 IPNDT-LASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGD 731 I +A +L I + + + P EN G+ V+D +VKSCAGYCVITYILGVGD Sbjct: 420 IQGSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGD 479 Query: 732 RHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCF 791 RHLDNLL+T G FH DFGYILG+DPKP PP MKL +++E GG +S Y +FR C+ Sbjct: 480 RHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCY 539 Query: 792 VAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLI 851 A+ LRR + LILNLF LM +NIPDI ++P+ + +V+++F L++S+E+A + Q+LI Sbjct: 540 TAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLI 599 Query: 852 NDSVNALLPIVIDHLH 867 ++SV+AL V++ +H Sbjct: 600 DESVHALFAAVVEQIH 615 >2X6F-A nrPDB Length = 696 Score = 415 bits (1067), Expect = e-116, Method: Compositional matrix adjust. Identities = 257/684 (37%), Positives = 390/684 (57%), Gaps = 88/684 (12%) Query: 277 IEEKYRRLERASKNANLDKQVKPDIKKRDYLNKII-NYPPGTKLTAHEKGSIWKYRYYLM 335 +E K+ RL R+ ++ D+ KP RD L+ I+ YPP L++ E+ +WK+R+YL Sbjct: 14 VERKHHRLARSERSGISDRDAKPTASIRDQLHTIVYRYPPTYVLSSEEQDLVWKFRFYLS 73 Query: 336 NNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRL 395 ++KKALTK L+ N + E E + L ++ +WA +D++DALELL TF + VR YAV+RL Sbjct: 74 SHKKALTKFLKCINWKLEDEVTQALWMLANWAPMDVEDALELLSPTFTHPQVRKYAVSRL 133 Query: 396 KKASDKELELYLLQLVEAVCFENLSTFSDKSNSEF--------------TIVDAVSSQKL 441 +A D++L LYLLQLV+A+ +E+ F +++D S L Sbjct: 134 AQAPDEDLLLYLLQLVQALKYEDPRHIVHLHGCIFPERDVVRSILDDNGSLLDQSSLSDL 193 Query: 442 SGDSMLLSTS--HANQK---LLKSISSES--------------------------ETSGT 470 S S L S ANQ+ +L +I S+ T G+ Sbjct: 194 SATSSGLHASVIPANQRAASVLAAIKSDKSVSPGSAGGSGSGGQGSVALPNPSAPATPGS 253 Query: 471 ESLPI-----------------VISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLD 513 SLP V + L FLI+RA N L ++FYWYL E E+ + Sbjct: 254 SSLPCDSNSNALMLAEGISFGSVPANLCTFLIQRACTNATLANYFYWYLSIEVEEVESVR 313 Query: 514 Q-----------ILSSFWSRLDKKSRNI------LNDQVRLINVLRECCETIKRLKDTTA 556 + +L F L+ + N+ L Q R I+ L + + + + Sbjct: 314 KQDERAHDMYAMVLKMFLKVLENGNFNLRGIFYNLRKQRRFIDELVKLVKLVAKEPGNRN 373 Query: 557 KKMELLVHLLETKVRPLVKV-----RPIALPLDPDVLICDVCPETSKVFKSSLSPLKITF 611 KK E LL + + KV PI PLDP++ I + P + +FKS+L P K+TF Sbjct: 374 KKTEKFQKLLAEQ--DMFKVNFTNFEPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTF 431 Query: 612 KTTL-NQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAI 670 T++ + Y +FK GDDLRQDQL++Q+I+LM++LL+ EN+DLKLTPYK+LAT + G + Sbjct: 432 VTSIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFL 491 Query: 671 EFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVG 730 +++ + T+A +L++ I + + H+P +N G+ V+D ++KSCAGYCVITY+LGVG Sbjct: 492 QYVDSCTVAEVLAREGNIHNFFRKHHPCDNGPYGISAEVMDTYIKSCAGYCVITYLLGVG 551 Query: 731 DRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYC 790 DRHLDNLL+T +G FH DFGYILG+DPKP PP MKL +++EA GG S ++ +FR C Sbjct: 552 DRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMKLSKEMVEAMGGISSEHHHEFRKQC 611 Query: 791 FVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNL 850 + AY LRR+A ++LNLF LM + +PDI ++P+ A+ +V E L +++E+A H Q+L Sbjct: 612 YTAYLHLRRHANVMLNLFSLMVDATVPDIALEPDKAVKKVEENLQLGLTDEEAVQHLQSL 671 Query: 851 INDSVNALLPIVIDHLHNLAQYWR 874 ++ S+ A++P +++ +H QYWR Sbjct: 672 LDVSITAVMPALVEQIHRFTQYWR 695 >5DXT-A nrPDB Length = 962 Score = 210 bits (535), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 178/664 (26%), Positives = 306/664 (46%), Gaps = 100/664 (15%) Query: 245 PNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKY-----RRLERASKNANLDKQVKP 299 PN+ P +++ D + S +KF P+ IEE R + +A L ++ Sbjct: 360 PNKETPCLELEF-DWFSSVVKF-----PDMSVIEEHANWSVSREAGFSYSHAGLSNRLAR 413 Query: 300 DIKKRD----YLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESE 355 D + R+ L I P +++T EK +W +R+Y + + L KLL S E Sbjct: 414 DNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDE 473 Query: 356 RVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVC 415 ++ L+ W I + A+ELL + + VR +AV + LE YL Sbjct: 474 VAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAV--------RCLEKYL-------- 517 Query: 416 FENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPI 475 +D S++ I +L++ + E Sbjct: 518 -------TDDKLSQYLI-----------------------QLVQVLKYEQYLDNL----- 542 Query: 476 VISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQ--ILSSFWSRLDKKSRNILND 533 L FL+++AL N R+G FF+W+LKSE +K + +L + R LN Sbjct: 543 ----LVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNR 598 Query: 534 QVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVRP--LVKVRPIALPLDPDVLICD 591 QV + L + +K+ K +K+++ L+E RP + ++ PL+P + + Sbjct: 599 QVEAMEKLINLTDILKQEKKDETQKVQMKF-LVEQMRRPDFMDALQGFLSPLNPAHQLGN 657 Query: 592 VCPETSKVFKSSLSPLKITFKT------TLNQPYHLMFKVGDDLRQDQLVVQIISLMNEL 645 + E ++ S+ PL + ++ L Q ++FK GDDLRQD L +QII +M + Sbjct: 658 LRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENI 717 Query: 646 LKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLK-----LHYPDEN 700 +N+ +DL++ PY L+ G G IE + N + G+ G L+ LH ++ Sbjct: 718 WQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKD 777 Query: 701 ATLG-VQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPK 759 G + +D F +SCAGYCV T+ILG+GDRH N++V DG FH DFG+ L K Sbjct: 778 KNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKK 837 Query: 760 PF-------PPLMKLPPQIIEAFGGAESSN---YDKFRSYCFVAYSILRRNAGLILNLFE 809 F P ++ I+ + G E + +++F+ C+ AY +R++A L +NLF Sbjct: 838 KFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFS 897 Query: 810 LMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHL-HN 868 +M S +P+++ + I +R+ L+ +E++A +F +ND+ + +D + H Sbjct: 898 MMLGSGMPELQSFDD--IAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHT 955 Query: 869 LAQY 872 + Q+ Sbjct: 956 IKQH 959 >4ANW-A nrPDB Length = 980 Score = 206 bits (523), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 172/617 (27%), Positives = 278/617 (45%), Gaps = 113/617 (18%) Query: 271 QPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKY 330 QP DP ++ R A + Q+ R L II P LTA +K +W + Sbjct: 395 QPTPDPEGDRVR--------AEMPNQL------RKQLEAIIATDPLNPLTAEDKELLWHF 440 Query: 331 RYYLMNNKKALTKLLQSTNLREE---SERVEVLELMDSW--AEIDIDDALELLGSTFKNL 385 RY + + KA KL S ++ ++ ++L + W + +D+ ++LL F + Sbjct: 441 RYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDE 500 Query: 386 SVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDS 445 +VR+ AV +L+ D ++ YLL Sbjct: 501 NVRAIAVQKLESLEDDDVLHYLL------------------------------------- 523 Query: 446 MLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSE 505 +L++++ E P S LA FL++R L N R+G F +W+L+SE Sbjct: 524 ----------QLVQAVKFE---------PYHDSALARFLLKRGLRNKRIGHFLFWFLRSE 564 Query: 506 SEDKPYLDQ----ILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMEL 561 + Q IL ++ + QV++I +L++ IK L Sbjct: 565 IAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQ 624 Query: 562 LVHLLETKVRPLVKVR---PIALPLDPDVLICDVCPETSKVFKSSLSPLKITFK----TT 614 ++ L+ K+ L + +P DP + + E KV S PL + FK T Sbjct: 625 VISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTA 684 Query: 615 L-NQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFI 673 L N+ ++FK GDDLRQD L++QI+ +M + + E++DL L PY ++TG + G IE + Sbjct: 685 LSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIV 744 Query: 674 PN-DTLASILSKYHGILG---------YLKLHYPDENATLGVQGWVLDNFVKSCAGYCVI 723 + T+A I G G +LK P E ++ FV SCAGYCV Sbjct: 745 KDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAA----VERFVYSCAGYCVA 800 Query: 724 TYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMK------LPPQ---IIEA 774 T++LG+GDRH DN+++T G+ FH DFG+ILG + K F + K L P ++ Sbjct: 801 TFVLGIGDRHNDNIMITETGNLFHIDFGHILG-NYKSFLGINKERVPFVLTPDFLFVMGT 859 Query: 775 FGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERF 834 G S ++ KF+ C AY LR + L++ LF +M + +P + + I +R+ Sbjct: 860 SGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKED--IEYIRDAL 917 Query: 835 NLNMSEEDATVHFQNLI 851 + +EEDA +F + I Sbjct: 918 TVGKNEEDAKKYFLDQI 934 >4AJW-A nrPDB Length = 934 Score = 203 bits (517), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 165/593 (27%), Positives = 275/593 (46%), Gaps = 91/593 (15%) Query: 307 LNKIINYPPGTKLTAHEKGSIWKYRYYLMNN-KKALTKLLQSTNLREESERVEVLELMDS 365 L +I+ +L HEK +WK R+ + + +AL +LL T + + ++L L+ S Sbjct: 401 LREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS 460 Query: 366 WAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDK 425 W EL +L +E + F +F D Sbjct: 461 WP------------------------------------ELPVLSALELLDF----SFPDC 480 Query: 426 SNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLI 485 F I S +KL+ D + Q LL+ + S + L +FL+ Sbjct: 481 YVGSFAIK---SLRKLTDDELF-------QYLLQLVQVLKYESYLDC------ELTKFLL 524 Query: 486 RRALVNPRLGSFFYWYLKSESEDKPYLDQ--ILSSFWSRLDKKSRNILNDQVRLINVLRE 543 RAL N ++G F +W+L+SE + ++ + R +L Q ++ L+ Sbjct: 525 GRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKA 584 Query: 544 CCETIK-RLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKS 602 + +K + TT + + ++H+ + + + + PLDP L+ +VC E S Sbjct: 585 LNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDS 644 Query: 603 SLSPLKITFKTTLNQP---YHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYK 659 + PL I + + ++FK GDDLRQD L +Q+I LM+ L K E +DL++TPY Sbjct: 645 KMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYG 704 Query: 660 ILATGPQEGAIEFI-PNDTLASI-LSKYH----------GILGYLKLHYPDENATLGVQG 707 L TG + G IE + +DT+A+I L+K + +L +LK P E + Sbjct: 705 CLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAI-- 762 Query: 708 WVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKL 767 + F SCAGYCV TY+LG+GDRH DN+++ G FH DFG+ LG F + Sbjct: 763 ---EEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRER 819 Query: 768 PP--------QIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDI 819 P +I+ S +++FR YC AY+ILRR+ L L+LF LM+ + +P++ Sbjct: 820 VPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPEL 879 Query: 820 RIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHL-HNLAQ 871 + I +++ L +EE+A HF+ N+++ ++ L HN+++ Sbjct: 880 SCSKD--IQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSK 930 >4BFR-A nrPDB Length = 952 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 155/576 (26%), Positives = 261/576 (45%), Gaps = 91/576 (15%) Query: 307 LNKIINYPPGTKLTAHEKGSIWKYRYYLMNN-KKALTKLLQSTNLREESERVEVLELMDS 365 L +I++ P ++L +E IW R N ++L KLL S + + ++ L+ Sbjct: 420 LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI 479 Query: 366 WAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDK 425 W ++ +ALELL + + VR YAV L++ SD+ Sbjct: 480 WPKLPPREALELLDFNYPDQYVREYAVGCLRQ------------------------MSDE 515 Query: 426 SNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLI 485 S++ + +L++ + E P + L+ FL+ Sbjct: 516 ELSQYLL-----------------------QLVQVLKYE---------PFLDCALSRFLL 543 Query: 486 RRALVNPRLGSFFYWYLKSESEDKPYLDQ--ILSSFWSRLDKKSRNILNDQVRLINVLRE 543 RAL N R+G F +W+L+SE Q ++ + R +L+ QV +N L+ Sbjct: 544 ERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKT 603 Query: 544 CCETIK--RLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFK 601 IK +K + AK E + H + + + PL+P V++ ++ E K Sbjct: 604 LNSLIKLNAVKLSRAKGKEAM-HTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD 662 Query: 602 SSLSPLKITFKTTL--NQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYK 659 S + PL + + + ++FK GDDLRQD L +Q++ LM+ L K +DL++ PY Sbjct: 663 SKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG 722 Query: 660 ILATGPQEGAIEFIP-NDTLASI-----------LSKYHGILGYLKLHYPDENATLGVQG 707 LATG + G IE + ++T+A I +L +LK + ++ ++ Sbjct: 723 CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIE- 781 Query: 708 WVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKL 767 F SCAGYCV +Y+LG+GDRH DN++V G FH DFG+ILG F + Sbjct: 782 ----EFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRER 837 Query: 768 PP--------QIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDI 819 P +I+ + + +FR C AY ILRR+ L + LF LM T+ +P++ Sbjct: 838 VPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPEL 897 Query: 820 RIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSV 855 + I +++ L SEE+A F+ ++++ Sbjct: 898 TSVKD--IQYLKDSLALGKSEEEALKQFKQKFDEAL 931 >5C4G-E nrPDB Length = 529 Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 125/243 (51%), Gaps = 10/243 (4%) Query: 621 LMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLAS 680 ++ K GDDLRQ+ L Q++ + + + E V L + PYKIL G IE + N Sbjct: 291 VIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIH 350 Query: 681 ILSKYHGILGYLKLHYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLL 738 + K + L ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L Sbjct: 351 QVKKQSQL--SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNIL 408 Query: 739 VTPDGHFFHADFGYILGQDPKPF---PPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYS 795 + +GH H DFG+IL P+ KL + ++ GG + ++ ++ Sbjct: 409 LDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI 468 Query: 796 ILRRNAGLILNLFELMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDS 854 R++ ++ + E+M+ S +P + I ++ERF+++M+EE + + +++ S Sbjct: 469 AARKHMDKVVQIVEIMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGS 526 Query: 855 VNA 857 + + Sbjct: 527 MRS 529 >4D0L-A nrPDB Length = 566 Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 125/243 (51%), Gaps = 10/243 (4%) Query: 621 LMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLAS 680 ++ K GDDLRQ+ L Q++ + + + E V L + PYKIL G IE + N Sbjct: 328 VIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIH 387 Query: 681 ILSKYHGILGYLKLHYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLL 738 + K + L ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L Sbjct: 388 QVKKQSQL--SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNIL 445 Query: 739 VTPDGHFFHADFGYILGQDPKPF---PPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYS 795 + +GH H DFG+IL P+ KL + ++ GG + ++ ++ Sbjct: 446 LDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI 505 Query: 796 ILRRNAGLILNLFELMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDS 854 R++ ++ + E+M+ S +P + I ++ERF+++M+EE + + +++ S Sbjct: 506 AARKHMDKVVQIVEIMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGS 563 Query: 855 VNA 857 + + Sbjct: 564 MRS 566 >6GL3-A nrPDB Length = 386 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 67/241 (27%), Positives = 124/241 (51%), Gaps = 10/241 (4%) Query: 621 LMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLAS 680 ++ K GDDLRQ+ L Q++ + + + E V L + PYKIL G IE + N Sbjct: 149 VIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIH 208 Query: 681 ILSKYHGILGYLKLHYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLL 738 + K + L ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L Sbjct: 209 QVKKQSQL--SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNIL 266 Query: 739 VTPDGHFFHADFGYILGQDPKPF---PPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYS 795 + +GH H DFG+IL P+ KL + ++ GG + ++ ++ Sbjct: 267 LDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI 326 Query: 796 ILRRNAGLILNLFELMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDS 854 R++ ++ + E+M+ S +P + I ++ERF+++M+EE + + +++ S Sbjct: 327 AARKHMDKVVQIVEIMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGS 384 Query: 855 V 855 + Sbjct: 385 M 385 >6FTQ-A nrPDB Length = 390 Score = 37.0 bits (84), Expect = 0.039, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 3/72 (4%) Query: 700 NATLGVQG---WVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQ 756 +AT+G W ++ + A +C I VG H N + DG H DFGY G Sbjct: 263 SATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFCSGDGKKAHQDFGYFYGS 322 Query: 757 DPKPFPPLMKLP 768 P + P Sbjct: 323 SYVAAPDSSRTP 334 >6NHI-A nrPDB Length = 457 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%) Query: 381 TFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSE 429 T + +S R Y +N L+K EL+ Q +E FENLST + K E Sbjct: 21 TAQEVSRRKYIINTLQK----NFELFGFQPLETPSFENLSTLTGKYGEE 65 >1WZO-A nrPDB Length = 246 Score = 29.6 bits (65), Expect = 6.7, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 35/75 (46%) Query: 604 LSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILAT 663 L P + + Q L V +LRQ+ +++ + ELL+ + + L PY +L T Sbjct: 154 LGPFLVVEEVEDPQDLWLRAYVNGELRQEGHTSRMLYSVAELLEFISEFMTLEPYDVLLT 213 Query: 664 GPQEGAIEFIPNDTL 678 G +G + P D + Sbjct: 214 GTPKGISQVRPGDVM 228 >2WSI-A nrPDB Length = 306 Score = 29.3 bits (64), Expect = 8.8, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 7/89 (7%) Query: 208 FPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFY 267 FPM LP VFI++E + L+ + L E R +++ D + +K Y Sbjct: 97 FPMQRLPTVFIDQEETFPTLENFVLETSERYCLSLYESQRQS-GASVNMADAFRDFIKIY 155 Query: 268 DPDQP------NNDPIEEKYRRLERASKN 290 + + DP E + ++R N Sbjct: 156 PETEAIVIGIRHTDPFGEALKPIQRTDSN 184 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5DFZ-C nrPDB 1389 0.0 2X6F-A nrPDB 686 0.0 6I3U-A nrPDB 676 0.0 5DXT-A nrPDB 667 0.0 4BFR-A nrPDB 607 e-174 4AJW-A nrPDB 590 e-169 4ANW-A nrPDB 570 e-162 6GL3-A nrPDB 288 6e-78 5C4G-E nrPDB 287 1e-77 4D0L-A nrPDB 286 3e-77 Sequences not found previously or not previously below threshold: 6FTQ-A nrPDB 37 0.044 3MGW-A nrPDB 32 0.98 2ENQ-A nrPDB 32 1.4 2WSI-A nrPDB 32 1.6 5YK0-A nrPDB 32 1.6 1WZO-A nrPDB 31 1.8 4AW2-A nrPDB 30 3.4 5A9Q-8 nrPDB 30 3.8 3UVF-A nrPDB 30 4.2 6AWL-A nrPDB 30 4.5 4RHP-A nrPDB 30 4.8 4RAP-A nrPDB 30 4.8 4Q2T-A nrPDB 30 5.9 4R3Z-B nrPDB 29 7.1 6E9W-A nrPDB 29 7.4 5FET-A nrPDB 29 8.3 2R70-A nrPDB 29 9.1 3NI7-A nrPDB 29 9.5 CONVERGED! >5DFZ-C nrPDB Length = 875 Score = 1389 bits (3596), Expect = 0.0, Method: Composition-based stats. Identities = 873/875 (99%), Positives = 874/875 (99%) Query: 1 MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL 60 M+LNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL Sbjct: 1 MALNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSL 60 Query: 61 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI 120 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI Sbjct: 61 QVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQI 120 Query: 121 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL 180 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL Sbjct: 121 PFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWL 180 Query: 181 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST 240 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST Sbjct: 181 DEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLST 240 Query: 241 DLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD 300 LREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD Sbjct: 241 GLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPD 300 Query: 301 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL 360 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL Sbjct: 301 IKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVL 360 Query: 361 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS 420 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS Sbjct: 361 ELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLS 420 Query: 421 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL 480 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL Sbjct: 421 TFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL 480 Query: 481 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV 540 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV Sbjct: 481 AEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINV 540 Query: 541 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF 600 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF Sbjct: 541 LRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVF 600 Query: 601 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI 660 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI Sbjct: 601 KSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKI 660 Query: 661 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY 720 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY Sbjct: 661 LATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGY 720 Query: 721 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES 780 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES Sbjct: 721 CVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAES 780 Query: 781 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE 840 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE Sbjct: 781 SNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSE 840 Query: 841 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT 875 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT Sbjct: 841 EDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT 875 >2X6F-A nrPDB Length = 696 Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats. Identities = 255/682 (37%), Positives = 387/682 (56%), Gaps = 84/682 (12%) Query: 277 IEEKYRRLERASKNANLDKQVKPDIKKRDYLNKII-NYPPGTKLTAHEKGSIWKYRYYLM 335 +E K+ RL R+ ++ D+ KP RD L+ I+ YPP L++ E+ +WK+R+YL Sbjct: 14 VERKHHRLARSERSGISDRDAKPTASIRDQLHTIVYRYPPTYVLSSEEQDLVWKFRFYLS 73 Query: 336 NNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRL 395 ++KKALTK L+ N + E E + L ++ +WA +D++DALELL TF + VR YAV+RL Sbjct: 74 SHKKALTKFLKCINWKLEDEVTQALWMLANWAPMDVEDALELLSPTFTHPQVRKYAVSRL 133 Query: 396 KKASDKELELYLLQLVEAVCFENLSTFSDKSNSEF--------------TIVDAVSSQKL 441 +A D++L LYLLQLV+A+ +E+ F +++D S L Sbjct: 134 AQAPDEDLLLYLLQLVQALKYEDPRHIVHLHGCIFPERDVVRSILDDNGSLLDQSSLSDL 193 Query: 442 SGDSMLLSTS--HANQK---LLKSISSES--------------------------ETSGT 470 S S L S ANQ+ +L +I S+ T G+ Sbjct: 194 SATSSGLHASVIPANQRAASVLAAIKSDKSVSPGSAGGSGSGGQGSVALPNPSAPATPGS 253 Query: 471 ESLPI-----------------VISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLD 513 SLP V + L FLI+RA N L ++FYWYL E E+ + Sbjct: 254 SSLPCDSNSNALMLAEGISFGSVPANLCTFLIQRACTNATLANYFYWYLSIEVEEVESVR 313 Query: 514 Q-----------ILSSFWSRLDKKSRNI------LNDQVRLINVLRECCETIKRLKDTTA 556 + +L F L+ + N+ L Q R I+ L + + + + Sbjct: 314 KQDERAHDMYAMVLKMFLKVLENGNFNLRGIFYNLRKQRRFIDELVKLVKLVAKEPGNRN 373 Query: 557 KKMELLVHLLETKVR---PLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKT 613 KK E LL + PI PLDP++ I + P + +FKS+L P K+TF T Sbjct: 374 KKTEKFQKLLAEQDMFKVNFTNFEPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVT 433 Query: 614 TL-NQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEF 672 ++ + Y +FK GDDLRQDQL++Q+I+LM++LL+ EN+DLKLTPYK+LAT + G +++ Sbjct: 434 SIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQY 493 Query: 673 IPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDR 732 + + T+A +L++ I + + H+P +N G+ V+D ++KSCAGYCVITY+LGVGDR Sbjct: 494 VDSCTVAEVLAREGNIHNFFRKHHPCDNGPYGISAEVMDTYIKSCAGYCVITYLLGVGDR 553 Query: 733 HLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFV 792 HLDNLL+T +G FH DFGYILG+DPKP PP MKL +++EA GG S ++ +FR C+ Sbjct: 554 HLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMKLSKEMVEAMGGISSEHHHEFRKQCYT 613 Query: 793 AYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLIN 852 AY LRR+A ++LNLF LM + +PDI ++P+ A+ +V E L +++E+A H Q+L++ Sbjct: 614 AYLHLRRHANVMLNLFSLMVDATVPDIALEPDKAVKKVEENLQLGLTDEEAVQHLQSLLD 673 Query: 853 DSVNALLPIVIDHLHNLAQYWR 874 S+ A++P +++ +H QYWR Sbjct: 674 VSITAVMPALVEQIHRFTQYWR 695 >6I3U-A nrPDB Length = 615 Score = 676 bits (1744), Expect = 0.0, Method: Composition-based stats. Identities = 248/615 (40%), Positives = 369/615 (60%), Gaps = 30/615 (4%) Query: 280 KYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKK 339 K+ +L R+ ++ D +KP+ RD LN I++YPP +LT E+ +WK+RYYL N +K Sbjct: 4 KHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEK 63 Query: 340 ALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKAS 399 ALTK L+ N E + LEL+ W +D++D+LELL S + N +VR YAV RL++A Sbjct: 64 ALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQAD 123 Query: 400 DKELELYLLQLVEAVCFENLSTFSD-----KSNSEFTIVDAVSSQKLS----GDSMLLST 450 D++L +YLLQLV+A+ +EN + K +S+ ++ + VS+ ++ S ++++ Sbjct: 124 DEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITS 183 Query: 451 SHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKP 510 + S E E+L L FLI RA N L ++ YWY+ E ED+ Sbjct: 184 PLPSVSSPPPASKTKEVPDGENLE---QDLCTFLISRACKNSTLANYLYWYVIVECEDQD 240 Query: 511 YLDQ----------ILSSFWSRLDKKS------RNILNDQVRLINVLRECCETIKRLKDT 554 + ++ F L K R++L Q ++ L + ++R Sbjct: 241 TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGN 300 Query: 555 TAKKMELLVHLL-ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKT 613 KK E L LL + + L V I LPL+P V I + PET+ + KS+ P ++ FKT Sbjct: 301 RKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLAKSANMPAQLFFKT 360 Query: 614 TLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFI 673 Y ++FK GDDLRQDQL++QIISLM++LL+ EN+DLKLTPYK+LAT + G +++I Sbjct: 361 EDGGKYPVLFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFLQWI 420 Query: 674 PNDT-LASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDR 732 +A +L I + + + P EN G+ V+D +VKSCAGYCVITYILGVGDR Sbjct: 421 QGSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDR 480 Query: 733 HLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFV 792 HLDNLL+T G FH DFGYILG+DPKP PP MKL +++E GG +S Y +FR C+ Sbjct: 481 HLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYT 540 Query: 793 AYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLIN 852 A+ LRR + LILNLF LM +NIPDI ++P+ + +V+++F L++S+E+A + Q+LI+ Sbjct: 541 AFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLID 600 Query: 853 DSVNALLPIVIDHLH 867 +SV+AL V++ +H Sbjct: 601 ESVHALFAAVVEQIH 615 >5DXT-A nrPDB Length = 962 Score = 667 bits (1722), Expect = 0.0, Method: Composition-based stats. Identities = 181/674 (26%), Positives = 309/674 (45%), Gaps = 101/674 (14%) Query: 235 NPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKY-----RRLERASK 289 NP T PN+ P +++ D + S +KF P+ IEE R + Sbjct: 351 NPIGVTG-SNPNKETPCLELEF-DWFSSVVKF-----PDMSVIEEHANWSVSREAGFSYS 403 Query: 290 NANLDKQVKPDIKKRD----YLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLL 345 +A L ++ D + R+ L I P +++T EK +W +R+Y + + L KLL Sbjct: 404 HAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLL 463 Query: 346 QSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELEL 405 S E ++ L+ W I + A+ELL + + VR +AV + LE Sbjct: 464 LSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAV--------RCLEK 515 Query: 406 YLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSES 465 YL +D S++ I +L++ + E Sbjct: 516 YL---------------TDDKLSQYLI-----------------------QLVQVLKYEQ 537 Query: 466 ETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQ--ILSSFWSRL 523 L FL+++AL N R+G FF+W+LKSE +K + +L + R Sbjct: 538 YLDNL---------LVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRA 588 Query: 524 DKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVRP--LVKVRPIAL 581 LN QV + L + +K+ K +K+++ L+E RP + ++ Sbjct: 589 CGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKF-LVEQMRRPDFMDALQGFLS 647 Query: 582 PLDPDVLICDVCPETSKVFKSSLSPLKITFKT------TLNQPYHLMFKVGDDLRQDQLV 635 PL+P + ++ E ++ S+ PL + ++ L Q ++FK GDDLRQD L Sbjct: 648 PLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLT 707 Query: 636 VQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLK-- 693 +QII +M + +N+ +DL++ PY L+ G G IE + N + G+ G L+ Sbjct: 708 LQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFN 767 Query: 694 ---LHYPDENATLG-VQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHAD 749 LH ++ G + +D F +SCAGYCV T+ILG+GDRH N++V DG FH D Sbjct: 768 SHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHID 827 Query: 750 FGYILGQDPKPF-------PPLMKLPPQIIEAFGGAESSN---YDKFRSYCFVAYSILRR 799 FG+ L K F P ++ I+ + G E + +++F+ C+ AY +R+ Sbjct: 828 FGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQ 887 Query: 800 NAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALL 859 +A L +NLF +M S +P+++ + I +R+ L+ +E++A +F +ND+ + Sbjct: 888 HANLFINLFSMMLGSGMPELQSFDD--IAYIRKTLALDKTEQEALEYFMKQMNDAHHGGW 945 Query: 860 PIVIDHL-HNLAQY 872 +D + H + Q+ Sbjct: 946 TTKMDWIFHTIKQH 959 >4BFR-A nrPDB Length = 952 Score = 607 bits (1565), Expect = e-174, Method: Composition-based stats. Identities = 168/632 (26%), Positives = 280/632 (44%), Gaps = 95/632 (15%) Query: 272 PNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYR 331 P D I EK L + K + L +I++ P ++L +E IW R Sbjct: 388 PPFDKIIEKAAELASGDSANVSSRGGKKFLAV---LKEILDRDPLSQLCENEMDLIWTLR 444 Query: 332 YYLMNN-KKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSY 390 N ++L KLL S + + ++ L+ W ++ +ALELL + + VR Y Sbjct: 445 QDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREY 504 Query: 391 AVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLST 450 AV L++ SD+EL YLL Sbjct: 505 AVGCLRQMSDEELSQYLL------------------------------------------ 522 Query: 451 SHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKP 510 +L++ + E P + L+ FL+ RAL N R+G F +W+L+SE Sbjct: 523 -----QLVQVLKYE---------PFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPA 568 Query: 511 YLDQ--ILSSFWSRLDKKSRNILNDQVRLINVLRECCETIK--RLKDTTAKKMELLVHLL 566 Q ++ + R +L+ QV +N L+ IK +K + AK E + H Sbjct: 569 VSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAM-HTC 627 Query: 567 ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQ--PYHLMFK 624 + + + PL+P V++ ++ E K S + PL + + + ++FK Sbjct: 628 LKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFK 687 Query: 625 VGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIP-NDTLASIL- 682 GDDLRQD L +Q++ LM+ L K +DL++ PY LATG + G IE + ++T+A I Sbjct: 688 NGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQL 747 Query: 683 ----------SKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDR 732 +L +LK + ++ ++ F SCAGYCV +Y+LG+GDR Sbjct: 748 NSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIE-----EFTLSCAGYCVASYVLGIGDR 802 Query: 733 HLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPP--------QIIEAFGGAESSNYD 784 H DN++V G FH DFG+ILG F + P +I+ + + Sbjct: 803 HSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFG 862 Query: 785 KFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDAT 844 +FR C AY ILRR+ L + LF LM T+ +P++ + I +++ L SEE+A Sbjct: 863 RFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD--IQYLKDSLALGKSEEEAL 920 Query: 845 VHFQNLINDSVNALLPIVIDHL-HNLAQYWRT 875 F+ ++++ ++ + H + + +R+ Sbjct: 921 KQFKQKFDEALRESWTTKVNWMAHTVRKDYRS 952 >4AJW-A nrPDB Length = 934 Score = 590 bits (1522), Expect = e-169, Method: Composition-based stats. Identities = 169/629 (26%), Positives = 280/629 (44%), Gaps = 98/629 (15%) Query: 271 QPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKY 330 P P EK L R + ++ L +I+ +L HEK +WK Sbjct: 372 HPVYFPALEKILELGRHGERG-------RITEEELQLREILERRGSGELYEHEKDLVWKM 424 Query: 331 RYYLMNN-KKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRS 389 R+ + + +AL +LL T + + ++L L+ SW Sbjct: 425 RHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWP---------------------- 462 Query: 390 YAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLS 449 EL +L +E + F +F D F I S +KL+ D + Sbjct: 463 --------------ELPVLSALELLDF----SFPDCYVGSFAIK---SLRKLTDDELF-- 499 Query: 450 TSHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDK 509 Q LL+ + S + L +FL+ RAL N ++G F +W+L+SE Sbjct: 500 -----QYLLQLVQVLKYES------YLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVP 548 Query: 510 PYLDQ--ILSSFWSRLDKKSRNILNDQVRLINVLRECCETIK-RLKDTTAKKMELLVHLL 566 + ++ + R +L Q ++ L+ + +K + TT + + ++H+ Sbjct: 549 SVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMC 608 Query: 567 ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQP---YHLMF 623 + + + + PLDP L+ +VC E S + PL I + + ++F Sbjct: 609 MRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIF 668 Query: 624 KVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFI-PNDTLASIL 682 K GDDLRQD L +Q+I LM+ L K E +DL++TPY L TG + G IE + +DT+A+I Sbjct: 669 KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ 728 Query: 683 -----------SKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGD 731 +L +LK P E ++ F SCAGYCV TY+LG+GD Sbjct: 729 LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIE-----EFTLSCAGYCVATYVLGIGD 783 Query: 732 RHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPP--------QIIEAFGGAESSNY 783 RH DN+++ G FH DFG+ LG F + P +I+ S + Sbjct: 784 RHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF 843 Query: 784 DKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDA 843 ++FR YC AY+ILRR+ L L+LF LM+ + +P++ + I +++ L +EE+A Sbjct: 844 ERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKD--IQYLKDSLALGKTEEEA 901 Query: 844 TVHFQNLINDSVNALLPIVIDHL-HNLAQ 871 HF+ N+++ ++ L HN+++ Sbjct: 902 LKHFRVKFNEALRESWKTKVNWLAHNVSK 930 >4ANW-A nrPDB Length = 980 Score = 570 bits (1468), Expect = e-162, Method: Composition-based stats. Identities = 173/662 (26%), Positives = 283/662 (42%), Gaps = 114/662 (17%) Query: 240 TDLREPNRNDP-QIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVK 298 T P++ + I I L + H QP DP ++ R A + Q+ Sbjct: 365 TSATNPDKENSMSISILLDNYCHPIA--LPKHQPTPDPEGDRVR--------AEMPNQL- 413 Query: 299 PDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREES---E 355 R L II P LTA +K +W +RY + + KA KL S ++ + Sbjct: 414 -----RKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAK 468 Query: 356 RVEVLELMDSW--AEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEA 413 ++L + W + +D+ ++LL F + +VR+ AV +L+ D ++ YLLQ Sbjct: 469 TYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQ---- 524 Query: 414 VCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESL 473 L++++ E Sbjct: 525 -------------------------------------------LVQAVKFE--------- 532 Query: 474 PIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQ----ILSSFWSRLDKKSRN 529 P S LA FL++R L N R+G F +W+L+SE + Q IL ++ + Sbjct: 533 PYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLH 592 Query: 530 ILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVR---PIALPLDPD 586 QV++I +L++ IK L ++ L+ K+ L + +P DP Sbjct: 593 DFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPG 652 Query: 587 VLICDVCPETSKVFKSSLSPLKITFKTTL-----NQPYHLMFKVGDDLRQDQLVVQIISL 641 + + E KV S PL + FK N+ ++FK GDDLRQD L++QI+ + Sbjct: 653 LKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRI 712 Query: 642 MNELLKNENVDLKLTPYKILATGPQEGAIEFIPND-TLASILSKYHGILG---------Y 691 M + + E++DL L PY ++TG + G IE + + T+A I G G + Sbjct: 713 MESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHW 772 Query: 692 LKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFG 751 LK P E ++ FV SCAGYCV T++LG+GDRH DN+++T G+ FH DFG Sbjct: 773 LKEKSPTEEKFQA----AVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFG 828 Query: 752 YILGQDPKPFPPLMKLPP--------QIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGL 803 +ILG + P ++ G S ++ KF+ C AY LR + L Sbjct: 829 HILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNL 888 Query: 804 ILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVI 863 ++ LF +M + +P + + I +R+ + +EEDA +F + I + + Sbjct: 889 LIILFSMMLMTGMPQLTSKED--IEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQF 946 Query: 864 DH 865 + Sbjct: 947 NW 948 >6GL3-A nrPDB Length = 386 Score = 288 bits (738), Expect = 6e-78, Method: Composition-based stats. Identities = 67/242 (27%), Positives = 124/242 (51%), Gaps = 10/242 (4%) Query: 621 LMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLAS 680 ++ K GDDLRQ+ L Q++ + + + E V L + PYKIL G IE + N Sbjct: 149 VIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIH 208 Query: 681 ILSKYHGILGYLKLHYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLL 738 + K + L ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L Sbjct: 209 QVKKQSQL--SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNIL 266 Query: 739 VTPDGHFFHADFGYILGQDPKPFPP---LMKLPPQIIEAFGGAESSNYDKFRSYCFVAYS 795 + +GH H DFG+IL P+ KL + ++ GG + ++ ++ Sbjct: 267 LDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI 326 Query: 796 ILRRNAGLILNLFELMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDS 854 R++ ++ + E+M+ S +P + I ++ERF+++M+EE + + +++ S Sbjct: 327 AARKHMDKVVQIVEIMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGS 384 Query: 855 VN 856 + Sbjct: 385 MR 386 >5C4G-E nrPDB Length = 529 Score = 287 bits (735), Expect = 1e-77, Method: Composition-based stats. Identities = 113/529 (21%), Positives = 218/529 (41%), Gaps = 64/529 (12%) Query: 370 DIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSE 429 DI A+ L K V++Y NRL +++++ YL QL+ + ++ + Sbjct: 24 DISMAISYL-YNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNM--YIHMDEDVGDAIKP 80 Query: 430 FTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISP-LAEFLIRRA 488 + + S S LL ++++ IS++ + GT+ +++S L ++R Sbjct: 81 YIVHRCRQSINFSLQCALLLGAYSSDM---HISTQRHSRGTKLRKLILSDELKPANLKRT 137 Query: 489 LVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRL---DKKSRNILNDQVRLINVLRECC 545 NP++ E+ED+P F L K+ + + + ++ E Sbjct: 138 AANPKV----------ENEDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELS 187 Query: 546 ETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLS 605 +L H + V V + D + V + F ++ Sbjct: 188 LLNHKLPARVWLPTAGFDHHVVR-VPHTQAV--VLNSKDKAPYLIYVEVLECENFDTTSV 244 Query: 606 PLKI----------------------TFKTTLNQPYH---------LMFKVGDDLRQDQL 634 P +I + PY ++ K GDDLRQ+ L Sbjct: 245 PARIPENRRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELL 304 Query: 635 VVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKL 694 Q++ + + + E V L + PYKIL G IE + N + K + L Sbjct: 305 AFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL--SLLD 362 Query: 695 HYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGY 752 ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L+ +GH H DFG+ Sbjct: 363 YFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGF 422 Query: 753 ILGQDPKPFPP---LMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFE 809 IL P+ KL + ++ GG + ++ ++ R++ ++ + E Sbjct: 423 ILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVE 482 Query: 810 LMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNA 857 +M+ S +P + I ++ERF+++M+EE + + +++ S+ + Sbjct: 483 IMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 529 >4D0L-A nrPDB Length = 566 Score = 286 bits (732), Expect = 3e-77, Method: Composition-based stats. Identities = 67/243 (27%), Positives = 125/243 (51%), Gaps = 10/243 (4%) Query: 621 LMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLAS 680 ++ K GDDLRQ+ L Q++ + + + E V L + PYKIL G IE + N Sbjct: 328 VIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIH 387 Query: 681 ILSKYHGILGYLKLHYPDENATLGVQGWV--LDNFVKSCAGYCVITYILGVGDRHLDNLL 738 + K + L ++ E+ + + ++ NFV+SCAGYC++ Y+L V DRH N+L Sbjct: 388 QVKKQSQL--SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNIL 445 Query: 739 VTPDGHFFHADFGYILGQDPKPFPP---LMKLPPQIIEAFGGAESSNYDKFRSYCFVAYS 795 + +GH H DFG+IL P+ KL + ++ GG + ++ ++ Sbjct: 446 LDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI 505 Query: 796 ILRRNAGLILNLFELMKT-SNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDS 854 R++ ++ + E+M+ S +P + I ++ERF+++M+EE + + +++ S Sbjct: 506 AARKHMDKVVQIVEIMQQGSQLPCFH--GSSTIRNLKERFHMSMTEEQLQLLVEQMVDGS 563 Query: 855 VNA 857 + + Sbjct: 564 MRS 566 >6FTQ-A nrPDB Length = 390 Score = 36.6 bits (83), Expect = 0.044, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 679 ASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLL 738 A I+ +G L W ++ + A +C I VG H N Sbjct: 256 AEIIFNPSATIGALSE-----------SLWPIEARNAAIANHCFTCAINRVGTEHFPNEF 304 Query: 739 VTPDGHFFHADFGYILGQDPKPFP 762 + DG H DFGY G P Sbjct: 305 CSGDGKKAHQDFGYFYGSSYVAAP 328 >3MGW-A nrPDB Length = 181 Score = 32.4 bits (72), Expect = 0.98, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Query: 630 RQDQLVVQIISLMNELLKNENVDLKLTPYKILAT--GPQEGAIEFIPNDTLASILSKYHG 687 RQD+L +Q + ++L +++ V ++ YK L T G + G +A I+S+ Sbjct: 18 RQDKLTLQGVDASHKLAEHDLV--RMNKYKELITRVGQKHGL----DPAIIAGIISRESR 71 Query: 688 ILGYLKLHYPDENA 701 G H ++ Sbjct: 72 -AGSALDHGWGDHG 84 >2ENQ-A nrPDB Length = 158 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 12/27 (44%), Gaps = 2/27 (7%) Query: 235 NPGLSTDLREPNRNDPQIKISLGDKYH 261 NP T PN+ P +++ D + Sbjct: 134 NPIGVTG-SNPNKETPCLELEF-DWFS 158 >2WSI-A nrPDB Length = 306 Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 40/98 (40%), Gaps = 7/98 (7%) Query: 208 FPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFY 267 FPM LP VFI++E + L+ + L E R +++ D + +K Y Sbjct: 97 FPMQRLPTVFIDQEETFPTLENFVLETSERYCLSLYESQRQSGA-SVNMADAFRDFIKIY 155 Query: 268 DPDQP------NNDPIEEKYRRLERASKNANLDKQVKP 299 + + DP E + ++R N +++P Sbjct: 156 PETEAIVIGIRHTDPFGEALKPIQRTDSNWPDFMRLQP 193 >5YK0-A nrPDB Length = 452 Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 3/38 (7%) Query: 730 GDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKL 767 GD H N ++ PDG DFG + P P ++L Sbjct: 290 GDAHPGNFMLLPDGRMGIIDFGAV---APMPGGFPIEL 324 >1WZO-A nrPDB Length = 246 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 32/67 (47%) Query: 628 DLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHG 687 +LRQ+ +++ + ELL+ + + L PY +L TG +G + P D + + Sbjct: 178 ELRQEGHTSRMLYSVAELLEFISEFMTLEPYDVLLTGTPKGISQVRPGDVMRLEIEGLGA 237 Query: 688 ILGYLKL 694 + ++ Sbjct: 238 LENPIEE 244 >4AW2-A nrPDB Length = 437 Score = 30.5 bits (67), Expect = 3.4, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 41/121 (33%), Gaps = 18/121 (14%) Query: 677 TLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHL-- 734 T + L + +Y + L + D + A + + ++ + H Sbjct: 137 TTLHYAFQDDNNLYLVMDYYVGGDL-LTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLH 195 Query: 735 --------DNLLVTPDGHFFHADFGYILG-------QDPKPFPPLMKLPPQIIEAFGGAE 779 DN+L+ +GH ADFG L Q + P+I++A G + Sbjct: 196 YVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEGGK 255 Query: 780 S 780 Sbjct: 256 G 256 >5A9Q-8 nrPDB Length = 656 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 479 PLAEFLIRRALVNPRLGSFFYWYLKSESEDKP--YLDQILSSFWSRLDKKSRNILNDQVR 536 + + L +A+ N RLGS W ++++ D+ L + R +++++ Sbjct: 468 SICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGP 527 Query: 537 LI 538 + Sbjct: 528 AM 529 >3UVF-A nrPDB Length = 255 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 57 IVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDY 90 +VSL++ DK +N LPI+ Y P +++ +DY Sbjct: 67 MVSLRIRDKNHLKNFILPIFDKY-PMLSNKQYDY 99 >6AWL-A nrPDB Length = 318 Score = 30.1 bits (66), Expect = 4.5, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 31/105 (29%), Gaps = 5/105 (4%) Query: 758 PKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIP 817 P P + L +++ F Y A N ++ M + P Sbjct: 210 PHNIPSSLSLLTSMVDDMWHYAGDQSTDFNWYTRRAMLAAIYNTTELV-----MMQDSSP 264 Query: 818 DIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIV 862 D RV + N+ + + + L+ + A + + Sbjct: 265 DFEDTWRFLENRVNDAMNMGHTAKQVKSTGEALVQGLMGAAVTLK 309 >4RHP-A nrPDB Length = 235 Score = 30.1 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 31/105 (29%), Gaps = 5/105 (4%) Query: 758 PKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIP 817 P P + L +++ F Y A N ++ M + P Sbjct: 127 PHNIPSSLSLLTSMVDDMWHYAGDQSTDFNWYTRRAMLAAIYNTTELV-----MMQDSSP 181 Query: 818 DIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIV 862 D RV + N+ + + + L+ + A + + Sbjct: 182 DFEDTWRFLENRVNDAMNMGHTAKQVKSTGEALVQGLMGAAVTLK 226 >4RAP-A nrPDB Length = 406 Score = 30.1 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Query: 723 ITYILGV---GDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLP-PQIIEA 774 TY +G+ GD + + G FH GYILG DP+ P + L P++I A Sbjct: 163 ATYRVGLYFGGDTNNQPVDFRKVG--FHRSAGYILGVDPREAPVRLDLSAPRVIAA 216 >4Q2T-A nrPDB Length = 607 Score = 29.7 bits (65), Expect = 5.9, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 21/45 (46%) Query: 744 HFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRS 788 FHA FG +LG+D K F ++++ G + DK + Sbjct: 382 RVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKE 426 >4R3Z-B nrPDB Length = 675 Score = 29.3 bits (64), Expect = 7.1, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 21/45 (46%) Query: 744 HFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRS 788 FHA FG +LG+D K F ++++ G + DK + Sbjct: 450 RVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKE 494 >6E9W-A nrPDB Length = 443 Score = 29.3 bits (64), Expect = 7.4, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 23/50 (46%), Gaps = 7/50 (14%) Query: 735 DNLLVTPDGHFFHADFGYILGQDPKPF-------PPLMKLPPQIIEAFGG 777 DN+L+ GH ADFG + + + + P+++++ GG Sbjct: 230 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGG 279 >5FET-A nrPDB Length = 847 Score = 29.3 bits (64), Expect = 8.3, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 731 DRHLDNLLVTPDGHFFHADFG---YILGQDPKPFPPLMKLPPQIIEAFG 776 D +N+L+ G+ DFG I G+ + P++I G Sbjct: 658 DLKPENILLDKQGYVKLIDFGCAKKIQGRAYTLVGTPHYMAPEVILGKG 706 >2R70-A nrPDB Length = 852 Score = 28.9 bits (63), Expect = 9.1, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 38/101 (37%), Gaps = 6/101 (5%) Query: 218 IEREI--MNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNND 275 IER I + ++ L PG + EP ++ P +++ L + Y D Sbjct: 537 IERSIDDIRGKLRQLVLLAQPGYLSGGVEPEQSSPTVELDLLGWSAT----YSKDLGIYV 592 Query: 276 PIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPG 316 P+ +K R A+ ++ + + K++ Y Sbjct: 593 PVLDKERLFCSAAYPKGVENKSLKSKVGIEQAYKVVRYEAL 633 >3NI7-A nrPDB Length = 213 Score = 28.9 bits (63), Expect = 9.5, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 66/173 (38%), Gaps = 26/173 (15%) Query: 371 IDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVC--FENLSTFSDKSNS 428 +D A+EL + +VR Y + S E+ LY + E + F+ + K Sbjct: 13 VDTAVEL-AAHTSWEAVRLYDIAARLAVSLDEIRLYFREKDELIDAWFDRADSRMLKEAE 71 Query: 429 EFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPL-------- 480 +D V+S+++ M+ + A Q+ + S+ + + + Sbjct: 72 SAGFLDLVASERIHHLIMIWLDALAVQRKVTRQMIMSKLEFGHIHIQIPAVMRVSRTVQW 131 Query: 481 --------AEFLIRRALVNPRLGS-----FFYWYLKSESEDKPYLDQILSSFW 520 A F+ RRAL L + FF+W ++ ESE+ + Q L Sbjct: 132 VREAAQRDATFM-RRALEESTLTTIYLMTFFFW-MRDESENSRHTRQFLKRHL 182 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.129 0.357 Lambda K H 0.267 0.0388 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,077,885 Number of Sequences: 36641 Number of extensions: 1339962 Number of successful extensions: 3630 Number of sequences better than 10.0: 33 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 3502 Number of HSP's gapped (non-prelim): 77 length of query: 875 length of database: 10,336,785 effective HSP length: 106 effective length of query: 769 effective length of database: 6,452,839 effective search space: 4962233191 effective search space used: 4962233191 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)