BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P22188 (495 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1E8C-A nrPDB 1012 0.0 2WTZ-A nrPDB 226 1e-59 4C12-A nrPDB 215 4e-56 4BUB-A nrPDB 210 1e-54 3ZL8-A nrPDB 74 2e-13 4QDI-A nrPDB 64 2e-10 4CVK-A nrPDB 60 2e-09 3LK7-A nrPDB 60 3e-09 3ZM5-A nrPDB 49 3e-06 2JFH-A nrPDB 46 3e-05 1J6U-A nrPDB 45 6e-05 4HV4-A nrPDB 40 0.003 1GG4-A nrPDB 39 0.007 4BUC-A nrPDB 37 0.021 6H5E-B nrPDB 37 0.024 2F00-A nrPDB 37 0.027 3HN7-A nrPDB 37 0.028 1GQY-A nrPDB 35 0.050 2Q7X-A nrPDB 35 0.052 1FGS-A nrPDB 33 0.24 5ANP-A nrPDB 31 1.6 6FQB-A nrPDB 30 1.9 5F7C-A nrPDB 30 2.9 3IG0-A nrPDB 30 3.1 5VVW-A nrPDB 28 8.3 >1E8C-A nrPDB Length = 498 Score = 1012 bits (2617), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/494 (100%), Positives = 494/494 (100%) Query: 2 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA 61 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA Sbjct: 1 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA 60 Query: 62 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT 121 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT Sbjct: 61 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT 120 Query: 122 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA 181 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA Sbjct: 121 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA 180 Query: 182 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA 241 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA Sbjct: 181 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA 240 Query: 242 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES 301 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES Sbjct: 241 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES 300 Query: 302 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT 361 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT Sbjct: 301 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT 360 Query: 362 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP 421 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP Sbjct: 361 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP 420 Query: 422 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY 481 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY Sbjct: 421 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY 480 Query: 482 SDRVTVARLLGVIA 495 SDRVTVARLLGVIA Sbjct: 481 SDRVTVARLLGVIA 494 >2WTZ-A nrPDB Length = 535 Score = 226 bits (577), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 187/475 (39%), Positives = 256/475 (53%), Gaps = 21/475 (4%) Query: 20 RALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREM 79 R + +TL ++ + GDLF A+ G G R++ AIA+G A++ D A EI Sbjct: 60 RTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVL---TDPAGVAEIAGR 116 Query: 80 HGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISA 139 VPV+ L LA Y PS+ L ++G+TGT+GKTTTT L+ + G ++ Sbjct: 117 AAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAG 176 Query: 140 VMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKF 199 ++GT+G + G +P+ TT A +Q LA +V++G MEVSSH L RV +F Sbjct: 177 LIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRF 236 Query: 200 AASVFTNLSRDHLDYHGDMEHYEAAKWLLY---SEHHCGQAIINADDEVGRRWLAKLPDA 256 A FTNLSRDHLD+H M Y AK L+ S A++ DD+ GR A+ DA Sbjct: 237 AVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADA 296 Query: 257 VAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDG---EIESHLMGAFNVSNLL 313 + VS D H W +AT+V D+G +F++ G I L G +NV+N L Sbjct: 297 ITVSAADR---PAH--W-RATDVAPTDAGGQ-QFTAIDPAGVGHHIGIRLPGRYNVANCL 349 Query: 314 LALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAAR 373 +ALA L +G + ++ V GR+E +VDYAH P+AL L Sbjct: 350 VALAILDTVGVSPEQAVPGLREIR-VPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL- 407 Query: 374 LHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGML 433 H +L VFG GGDRD GKR MG IA + AD+ VVTDDNPR E+P AI +ILAG Sbjct: 408 AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAA 467 Query: 434 D-AGHAKVME--GRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRV 485 + G A+V+E R +A+ AV A+ DVVL+AGKGHE Q G + + DRV Sbjct: 468 EVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRV 522 >4C12-A nrPDB Length = 501 Score = 215 bits (547), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 143/462 (30%), Positives = 227/462 (49%), Gaps = 24/462 (5%) Query: 20 RALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREM 79 + + ++T DSR A G +FVA VG+ D ++ QG ++ K+++ + + Sbjct: 21 QQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVN-KEQSLPANVTQ- 78 Query: 80 HGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISA 139 + + S LA Y PS L GVTGTNGKT+ ++ + L + SA Sbjct: 79 -----VVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSA 133 Query: 140 VMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKF 199 +GT G + NTT V + ++ VD GA +EVSSHGLV R+ ++F Sbjct: 134 YLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEF 193 Query: 200 AASVFTNLSRDHLDYHGDMEHYEAAKWLLYSE-----HHCGQAIINADDEVGRRWLAKLP 254 ++F+NL++DHLD+HG ME Y AK LL+S+ ++N DD P Sbjct: 194 DVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTP 253 Query: 255 DAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLL 314 V D +++ A + G + F + +G ++S +G FN+SN++ Sbjct: 254 YEVFSYGIDE-----EAQFM-AKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIMA 307 Query: 315 ALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARL 374 A+ + + G L ++K L+PV GR+EV +++DYAHT D + K + A + Sbjct: 308 AMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQP 367 Query: 375 HCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLD 434 KL + G G+RD K P MG +A AD + T DNP ++P+ + ++ G Sbjct: 368 FVKQKLIFLVGMAGERDLTKTPEMGRVACR-ADYVIFTPDNPANDDPKMLTAELAKG--- 423 Query: 435 AGHAKVME--GRAEAVTCAVMQAKENDVVLVAGKGHEDYQIV 474 A H +E RAE + A+ A+ D V++A KG E YQI+ Sbjct: 424 ATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIM 465 >4BUB-A nrPDB Length = 498 Score = 210 bits (534), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 159/469 (33%), Positives = 240/469 (51%), Gaps = 27/469 (5%) Query: 29 SRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLS 88 S GDLF+ G + D IP+ + +G A++ E RE+ + Y+ Sbjct: 32 SSKVKKGDLFICRRGEKFDSHEIIPEVMEKGAVAVVVE----------REID-LDFPYIQ 80 Query: 89 QLNERL--SALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGN 146 + R + +A F+ +P ++ GVTGTNGKTTTT ++ LGE +V+ T Sbjct: 81 VFDSRYFEAKVASLFFEDPWKDVLTFGVTGTNGKTTTTMMIYHMLTSLGERGSVLTTAVK 140 Query: 147 GLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTN 206 +LG + TT A+ + + + G F A+EVSSH LVQ RV ++F +FTN Sbjct: 141 RILGNSYYDDITTPDAITILSAMKENREGGGKFFALEVSSHALVQQRVEGVRFDVGIFTN 200 Query: 207 LSRDHLDYHGDMEHYEAAKWLLYS-EHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHI 265 +SRDHLD+HG E+Y AK L+ G A++N LA + + + Sbjct: 201 ISRDHLDFHGTFENYLKAKLHLFDLLKDDGVAVLNES-------LADAFNRKSRKITFGT 253 Query: 266 NPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYP 325 + N R L EV++ G + G ++ + +G FN N A+A L LGY Sbjct: 254 SKNADYR-LGNIEVSWE--GTQFVLETPDGLLKVFTRAIGDFNAYNAAAAIAALHQLGYD 310 Query: 326 LADLLKTAARLQPVCGRMEVFTAPGKP--TVVVDYAHTPDALEKALQAARLHCAGKLWCV 383 DL + V GR EV K VVVD+AH+PDALEK L+ R G++ V Sbjct: 311 PKDLASSLETFTGVEGRFEVVRGAKKIGLNVVVDFAHSPDALEKLLKNVRKISQGRVIVV 370 Query: 384 FGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEG 443 FG GG+ D+GKRP+M +A + ADV ++T D+PR E+P I+ D++ G+ V+ Sbjct: 371 FGAGGNSDRGKRPMMSEVASKLADVVILTTDDPRGEDPEQIMEDLIKGIDKRKPYLVLFD 430 Query: 444 RAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQ-RLDYSDRVTVARLL 491 R EA+ A+ A D V++AG+GHE YQI+ + ++ + DR V ++ Sbjct: 431 RREAIETALTIANRGDSVVIAGRGHERYQIIDEEKKVPFQDREVVEEII 479 >3ZL8-A nrPDB Length = 437 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 98/378 (25%), Positives = 157/378 (41%), Gaps = 47/378 (12%) Query: 23 REMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGV 82 R L+S+ GD+FVAV G + DG +I +A+ G AIIAE K +D V Sbjct: 7 RRFVLNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIFLVESSV 66 Query: 83 PVIYLSQL-NERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVM 141 L++L E+L +G +VGVTG++GKTTT ++L LL +V Sbjct: 67 DT--LAKLAREKLGNFSG----------TVVGVTGSSGKTTTKEILY---NLLKNKRSVF 111 Query: 142 GTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAA 201 T GN + TE G + + ++ G + M S G + H Sbjct: 112 KTPGN------MNTE--YGLPLSILNDYKG---EEILVLEMAASRPGDIAHLCKIAPPDV 160 Query: 202 SVFTNLSRDHLDYHGDMEHYEAAKW-LLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVS 260 +V N+ HL++ G E K ++ A+ DD R+ + + + + Sbjct: 161 AVLLNVGSAHLEFFGTRERIMETKMEIIKHSKENAIAVTLFDDPDLRKEVPRYRNTLFFG 220 Query: 261 ME--DHINPN-CHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALA 317 E D + + + E DS T++ S W G++ N+ +L Sbjct: 221 KEGGDSVLKDWWYYEGSTIAEFEAFDSLFTVKLSGYWNGGQL----------LNIAASLC 270 Query: 318 TLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCA 377 + LG + D+ A+ L+ V GR V G V Y +P+A + +++A L Sbjct: 271 VMRTLGETV-DIFDLAS-LKTVPGRFNVREKKGVLIVDDTYNASPEAFQTSIEAL-LRFP 327 Query: 378 GKLWCVFGCG---GDRDK 392 GK + V G G+R K Sbjct: 328 GKKFAVVGAMKELGERSK 345 >4QDI-A nrPDB Length = 472 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 89/381 (23%), Positives = 145/381 (38%), Gaps = 75/381 (19%) Query: 13 WVPDA-PSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEA 71 W D P ++ + DSR A +GD F+A+ G + D ++ Q +A G I E Sbjct: 33 WHKDQIPQTEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVE---RP 89 Query: 72 TDGEIREMHGVPV-IYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQW 130 D EI ++ + L QL G + E + L+++ +TG++GKTTT ++L Sbjct: 90 IDAEIAQLVVADTRLALGQL--------GAYRREQNAQLKVIALTGSSGKTTTKEMLG-- 139 Query: 131 SQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLV 190 +L ++ PT T G+ + D G +E+ Sbjct: 140 ----------------SILSRLAPTLITRGNLNN---------DLGVPMMLLELRK---- 170 Query: 191 QHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQ-----AIINADDEV 245 +H+ A ++ A+ + +DY + A L H G+ I A E+ Sbjct: 171 EHQYAVMELGAN-----HQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEI 225 Query: 246 GRRWLAKLPDAVAV--------------SMEDHINPNCHGRWLKATEVNYHDSGATIRFS 291 R LP VA+ + I G + ATE+ A + Sbjct: 226 YRHI---LPQGVAIVPQQDDFTAEIREAAKSHQIMSFGEGGDVFATEIELLPQSANFQLH 282 Query: 292 SSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGK 351 + G + G NV N A+A LALG L D++K + Q GR+ Sbjct: 283 TPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQK--A 340 Query: 352 PTVVVD--YAHTPDALEKALQ 370 P + +D Y P ++ A Q Sbjct: 341 PHLFIDDTYNANPTSMRAAAQ 361 >4CVK-A nrPDB Length = 475 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 93/359 (25%), Positives = 154/359 (42%), Gaps = 49/359 (13%) Query: 25 MTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPV 84 ++ DSR G+LF+A+ G + DG Y+ + A+G A + E RE+ P+ Sbjct: 28 VSTDSRAIGPGELFIALSGPRFDGHDYLAEVAAKGAVAALVE----------REVADAPL 77 Query: 85 IYLSQLNER-----LSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQL-LGEIS 138 L + R L AL R + P L +TG++GKTT ++LA + G+ Sbjct: 78 PQLLVRDTRAALGRLGALNRRKFTGP-----LAAMTGSSGKTTVKEMLASILRTQAGDAE 132 Query: 139 AVMGTVGNGLLGKVIPTENTTGSAVDV-----QHELAGLVDQGATFCAMEVSSHGLVQHR 193 +V+ T GN N G + + QH A +++ GA S G + + Sbjct: 133 SVLATRGN--------LNNDLGVPLTLLQLAPQHRSA-VIELGA-------SRIGEIAYT 176 Query: 194 VAALKFAASVFTNLSRDHL-DYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAK 252 V + ++ TN H+ ++ G + EA +L G A++N DD+ W A+ Sbjct: 177 VELTRPHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKAR 236 Query: 253 LPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGAT-IRFSSSWGDGEIESHLMGAFNVSN 311 ++ P +A ++ G R G+ +++ +L+G NV+N Sbjct: 237 ASGRPLLTFSLD-RPQAD---FRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVAN 292 Query: 312 LLLALATLLALGYPLADLLKTAARLQPVCGR-MEVFTAPGKPTVVVDYAHTPDALEKAL 369 L A A ALG PL ++ LQPV GR + TA G + Y P ++ A+ Sbjct: 293 ALAAAAAAHALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAI 351 >3LK7-A nrPDB Length = 451 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 21/150 (14%) Query: 110 RLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHEL 169 +L+G+TG+NGKTTTT ++A+ G+ + G +G P +A D Sbjct: 113 QLIGITGSNGKTTTTTMIAEVLNAGGQRGLLAGNIG-------FPASEVVQAANDKDT-- 163 Query: 170 AGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLY 229 ME+SS L+ V + +V TNL HLDYHG E Y AAKW + Sbjct: 164 ----------LVMELSSFQLMG--VKEFRPHIAVITNLMPTHLDYHGSFEDYVAAKWNIQ 211 Query: 230 SEHHCGQAIINADDEVGRRWLAKLPDAVAV 259 ++ ++ ++ + LAK A V Sbjct: 212 NQMSSSDFLVLNFNQGISKELAKTTKATIV 241 >3ZM5-A nrPDB Length = 465 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 39/125 (31%), Positives = 56/125 (44%), Gaps = 16/125 (12%) Query: 22 LREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHG 81 L + DSR+ GDLFV + G + DG +I A G A ++E +E+ Sbjct: 26 LEKAEFDSRLIGTGDLFVPLKGAR-DGHDFIETAFENGAAVTLSE----------KEVSN 74 Query: 82 VPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVM 141 P I + + +LA Y+ + + VTG+NGKTTT +LA LL Sbjct: 75 HPYILVDDVLTAFQSLAS--YYLEKTTVDVFAVTGSNGKTTTKDMLA---HLLSTRYKTY 129 Query: 142 GTVGN 146 T GN Sbjct: 130 KTQGN 134 >2JFH-A nrPDB Length = 445 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 29/169 (17%) Query: 111 LVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELA 170 +V +TG+NGK+T T L+ + ++ G V G +G +P Sbjct: 107 IVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIG-------LPA--------------L 145 Query: 171 GLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDMEHYEAAKWLLY 229 L+D +E+SS L ++L+ A+ N++ DH+D Y ++ Y AAK +Y Sbjct: 146 MLLDDECELYVLELSSFQL--ETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIY 203 Query: 230 SEHHCGQAIINADDEVGR--RWLAKLPDAVAVSMED-HINPNCHGRWLK 275 ++NADD + R + + V+M D H+N WL+ Sbjct: 204 ENAKV--CVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLR 250 >1J6U-A nrPDB Length = 469 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 20/182 (10%) Query: 298 EIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEV-FTAPGKPTVVV 356 E++ + G NV N L +A +LGY LA +L+ + V R + F P V+ Sbjct: 268 ELKLKVPGFHNVLNALAVIALFDSLGYDLAPVLEALEEFRGVHRRFSIAFHDPETNIYVI 327 Query: 357 D-YAHTPDALEKALQAAR-LHCAGKLWCVFG----CGGDRDKGKRPLMGAIAEEFADVAV 410 D YAHTPD + LQ A+ + K+ +F +R+ G A A + AD V Sbjct: 328 DDYAHTPDEIRNLLQTAKEVFENEKIVVIFQPHRYSRLEREDGN----FAKALQLADEVV 383 Query: 411 VTDDNPRTEEPR-----AIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAG 465 VT+ EE + +I D L + A +E E V+ EN V L G Sbjct: 384 VTEVYDAFEEKKNGISGKMIWDSLKSL--GKEAYFVEKLPE--LEKVISVSENTVFLFVG 439 Query: 466 KG 467 G Sbjct: 440 AG 441 >4HV4-A nrPDB Length = 494 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 24/144 (16%) Query: 112 VGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAG 171 + V GT+GKTTTT +L S + E + + T NG L K T GS+ ++ +A Sbjct: 125 IAVAGTHGKTTTTAML---SSIYAE-AGLDPTFVNGGLVKAAGTHARLGSS---RYLIAE 177 Query: 172 LVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDMEHYEAAKW-LLY 229 + A+F L+ ++ TN+ DH+D Y GD E+ + L+ Sbjct: 178 ADESDASFL---------------HLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLH 222 Query: 230 SEHHCGQAIINADDEVGRRWLAKL 253 + G+A++ DD V R L ++ Sbjct: 223 NLPFYGRAVMCIDDPVVRELLPRV 246 >1GG4-A nrPDB Length = 452 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 36/326 (11%) Query: 22 LREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHG 81 L +T D+R G LFVA+ G + D + QA A G A++ + Sbjct: 24 LDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDID--------- 74 Query: 82 VPVIYLSQLNERLSALAGRFYHE-PSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAV 140 +P + + LA + P+ R+V +TG++GKT+ ++ A A+ Sbjct: 75 LPQLIVKDTRLAFGELAAWVRQQVPA---RVVALTGSSGKTSVKEMTA----------AI 121 Query: 141 MGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSH--GLVQHRVAALK 198 + GN L T + + V L L + + +E+ ++ G + V+ + Sbjct: 122 LSQCGNTLY-----TAGNLNNDIGVPMTLLRLTPE-YDYAVIELGANHQGEIAWTVSLTR 175 Query: 199 FAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSE-HHCGQAIINADDEVGRRWLAKLPDAV 257 A++ NL+ HL+ G + AK ++S G AI+NAD+ W + Sbjct: 176 PEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNW----QSVI 231 Query: 258 AVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALA 317 +PN AT ++ G + G ++ L G N++N L A A Sbjct: 232 GSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAA 291 Query: 318 TLLALGYPLADLLKTAARLQPVCGRM 343 +++G L + A L+ V GR+ Sbjct: 292 LSMSVGATLDAIKAGLANLKAVPGRL 317 >4BUC-A nrPDB Length = 450 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 23/126 (18%) Query: 100 RFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTT 159 +F+ + D ++VG+TGT+GK+T T A+M V +G K N Sbjct: 113 QFFLDNVDPKKVVGITGTDGKSTAT--------------ALMYHVLSGRGFKTFLGGNFG 158 Query: 160 GSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDME 219 AV+ L G D + +E+SS L L + + N+S DHLD+H + Sbjct: 159 TPAVEA---LEGEYD----YYVLEMSSFQLFWSERPYL--SNFLVLNISEDHLDWHSSFK 209 Query: 220 HYEAAK 225 Y +K Sbjct: 210 EYVDSK 215 >6H5E-B nrPDB Length = 437 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 63/311 (20%), Positives = 114/311 (36%), Gaps = 60/311 (19%) Query: 111 LVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGL---LGKVIPTENTTGSAVDVQH 167 +V ++GTNGKTTT+ L+ + I + G + + ++T + + V Sbjct: 50 IVFISGTNGKTTTSNLIGHTLKA-NNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIE 108 Query: 168 ELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWL 227 +D+G+ ++ + ++ VFTN RD +D G+++ + Sbjct: 109 -----IDEGSIPRVLKEVTPSMM------------VFTNFFRDQMDRFGEIDI--MVNNI 149 Query: 228 LYSEHHCG-QAIINADDEVGRRWLAKLPDAVAVSMEDHIN-------------PNCHGRW 273 + + G + ++NADD R V M+ H + PNC GR Sbjct: 150 AETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNC-GRL 208 Query: 274 LKATEVNYHDSG------------ATIRFSS---------SWGDGEIESHLMGAFNVSNL 312 L+ ++Y+ G A SS + D + + + G FN N Sbjct: 209 LQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNA 268 Query: 313 LLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAA 372 L A L LG + GRM+ F K +++ A P + +L Sbjct: 269 LAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKE-AMINLAKNPAGMNASLSVG 327 Query: 373 RLHCAGKLWCV 383 K++ + Sbjct: 328 EQLEGEKVYVI 338 >2F00-A nrPDB Length = 491 Score = 36.6 bits (83), Expect = 0.027, Method: Compositional matrix adjust. Identities = 74/306 (24%), Positives = 115/306 (37%), Gaps = 55/306 (17%) Query: 82 VPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVM 141 +PVI +++ L RF H + + GT+GKTTTT A S + E Sbjct: 103 IPVIRRAEMLAELM----RFRHG-------IAIAGTHGKTTTT---AMVSSIYAEAGLDP 148 Query: 142 GTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAA 201 V GL+ A V L G A S H L+ Sbjct: 149 TFVNGGLV-----------KAAGVHARLG----HGRYLIAEADESDASFLH----LQPMV 189 Query: 202 SVFTNLSRDHLD-YHGDMEHYEAAKW-LLYSEHHCGQAIINADDEVGRRWLAK------- 252 ++ TN+ DH+D Y GD E+ + L++ G+A++ DD V R L + Sbjct: 190 AIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTT 249 Query: 253 --LPDAVAVSMEDH--INPNCHGRWLKATEVNYHDS-GATIRFSSSWGDGEIESHLMGAF 307 + V +ED+ I P H L+ + + A R ++ + Sbjct: 250 YGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGI 309 Query: 308 NVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEK 367 + +L AL + G D L L+PV G+ G +V DY H P ++ Sbjct: 310 DDEAILRALESFQGTGRRF-DFLGEFP-LEPVNGKS------GTAMLVDDYGHHPTEVDA 361 Query: 368 ALQAAR 373 ++AAR Sbjct: 362 TIKAAR 367 >3HN7-A nrPDB Length = 524 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 39/191 (20%), Positives = 72/191 (37%), Gaps = 17/191 (8%) Query: 289 RFSSSWGDGE-----IESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRM 343 +F+ S+ D + + + G NV+N L+A+A +G + + + RM Sbjct: 319 QFTVSFNDNKEATALVNWSMSGLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRM 378 Query: 344 EVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAG-KLWCVFGCGGDRDKGKRPLMGAIA 402 E+ V D+AH P A+ L A+ A +LW + + K MG Sbjct: 379 ELIGDVNDILVFDDFAHHPTAITTTLDGAKKKLADRRLWAIIEPRSNTMK-----MGIHQ 433 Query: 403 EEFADVAVVTDDNPRTEEP------RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAK 456 + A A + D E + +I++ G +V+ + + AK Sbjct: 434 DSLAQSATLADHTLWYEPTGLEWGLKEVIDNATIANPSIGSQQVLSSVDDIIKHICTHAK 493 Query: 457 ENDVVLVAGKG 467 D +++ G Sbjct: 494 AGDAIVIMSNG 504 >1GQY-A nrPDB Length = 475 Score = 35.4 bits (80), Expect = 0.050, Method: Compositional matrix adjust. Identities = 55/216 (25%), Positives = 94/216 (43%), Gaps = 41/216 (18%) Query: 45 QADGRRYIPQAIA--QGVAAIIAEA--KDEATDGEIREMHGVPVIYLSQLNERLSALAGR 100 QA + YI A +G + ++ + KD+ + + +PVI +Q+ + R Sbjct: 61 QAGAKIYIGHAEEHIEGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIM----R 116 Query: 101 FYHEPSDNLRLVGVTGTNGKTTTTQLLAQ-WSQLLGEISAVMGTVGNGLLGKVIPTENTT 159 F H + V GT+GKTTTT +++ ++Q + + T NG L K Sbjct: 117 FRHG-------IAVAGTHGKTTTTAMISMIYTQ-----AKLDPTFVNGGLVKSAGKNAHL 164 Query: 160 GSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDM 218 G++ ++ +A + A+F L+ SV TN+ DH+D Y GD Sbjct: 165 GAS---RYLIAEADESDASFL---------------HLQPMVSVVTNMEPDHMDTYEGDF 206 Query: 219 EHYEAAK-WLLYSEHHCGQAIINADDEVGRRWLAKL 253 E +A L++ G A++ ADD V + K+ Sbjct: 207 EKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKV 242 >2Q7X-A nrPDB Length = 326 Score = 35.4 bits (80), Expect = 0.052, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 18/96 (18%) Query: 60 VAAIIAEAKDEATDGEIRE-----------------MHGVPVIYLSQLNERLSALAGRFY 102 +AAI+ A D + GE+R+ M +P Y R S AG F Sbjct: 30 IAAIVTVADDGGSSGELRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFA 89 Query: 103 HEPSDNLRLVGVTGTNGKT-TTTQLLAQWSQLLGEI 137 P NL + G++ G T QLL+++ G+I Sbjct: 90 GHPLGNLIIAGLSEMQGSTYNAMQLLSKFFHTTGKI 125 >1FGS-A nrPDB Length = 428 Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust. Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 24/180 (13%) Query: 289 RFSSSWGDGEI---ESHLMGAFNVSNLLLALATLLALG----YPLADL-LKTAARLQPVC 340 RF+ DG I E L+G + N+ +A+ T +PL ++ Sbjct: 239 RFTYEDQDGRISDLEVPLVGDYQQRNMAIAIQTAKVYAKQTEWPLTPQNIRQGLAASHWP 298 Query: 341 GRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGA 400 R+E + P +V+D AH PD + + A + + + + G D+D + Sbjct: 299 ARLEKIS--DTPLIVIDGAHNPDGINGLITALKQLFSQPITVIAGILADKDYAA--MADR 354 Query: 401 IAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDV 460 + F+ V +V P PRA + +AG+ + EGR + + A NDV Sbjct: 355 LTAAFSTVYLV----PVPGTPRA--------LPEAGYEALHEGRLKDSWQEALAASLNDV 402 >5ANP-A nrPDB Length = 277 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 18/33 (54%) Query: 336 LQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKA 368 LQPV G+ + P + T V DYA A EKA Sbjct: 28 LQPVLGQFTIPEVPKEQTSVYDYAELLSAAEKA 60 >6FQB-A nrPDB Length = 465 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 15/114 (13%) Query: 106 SDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDV 165 + N +V VTGTNGKT TT L +G + V G V P+ + + Sbjct: 63 AKNYEIVVVTGTNGKTLTTAL------TVGILKEVYGQVLTN------PSGANMITGIAT 110 Query: 166 QHELAGLVDQGATFCAMEVSSHGLVQHRVA-ALKFAASVFTNLSRDHLDYHGDM 218 A G +E+ L R+ ++ + V TN+ RD +D G++ Sbjct: 111 TFLTAKSSKTGKNIAVLEIDEASL--SRICDYIQPSLFVITNIFRDQMDRFGEI 162 >5F7C-A nrPDB Length = 761 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 20/34 (58%) Query: 222 EAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPD 255 + KW+L+++ +A+IN ++ RW LPD Sbjct: 112 QGGKWILFTQDGTKRAVINVEEPALDRWSELLPD 145 >3IG0-A nrPDB Length = 242 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 16 DAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRR 50 D R LR++TLD AAA +LF ++G D RR Sbjct: 194 DPSVRVLRQVTLDD-AAAADELFSILMGEDVDARR 227 >5VVW-A nrPDB Length = 315 Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust. Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 24/144 (16%) Query: 112 VGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAG 171 + V GT+GKTTTT L+A + A G ++G + T ++ +A Sbjct: 111 IAVAGTHGKTTTTSLIAS-------VFAAGGLDPTFVIGGRLNAAGTNAQLGASRYLVAE 163 Query: 172 LVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHL-DYHGDMEHYEAAKW-LLY 229 + A+F + Q VA V TN+ DH+ Y GD + L+ Sbjct: 164 ADESDASFLHL--------QPMVA-------VVTNIDADHMATYGGDFNKLKKTFVEFLH 208 Query: 230 SEHHCGQAIINADDEVGRRWLAKL 253 + G A++ DD V R L ++ Sbjct: 209 NLPFYGLAVMCVDDPVVREILPQI 232 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1E8C-A nrPDB 656 0.0 4C12-A nrPDB 488 e-138 4BUB-A nrPDB 447 e-126 2WTZ-A nrPDB 417 e-117 3ZL8-A nrPDB 292 2e-79 4QDI-A nrPDB 270 7e-73 4CVK-A nrPDB 235 4e-62 3ZM5-A nrPDB 172 5e-43 1J6U-A nrPDB 170 2e-42 3LK7-A nrPDB 163 1e-40 2JFH-A nrPDB 131 8e-31 Sequences not found previously or not previously below threshold: 1GG4-A nrPDB 166 2e-41 3HN7-A nrPDB 100 2e-21 6CAU-A nrPDB 96 4e-20 4HV4-A nrPDB 94 1e-19 2F00-A nrPDB 90 2e-18 1GQY-A nrPDB 87 1e-17 4BUC-A nrPDB 86 3e-17 5VVW-A nrPDB 75 6e-14 6H5E-B nrPDB 73 3e-13 3EAG-A nrPDB 70 2e-12 6FQB-A nrPDB 60 2e-09 1FGS-A nrPDB 58 1e-08 2VOR-A nrPDB 52 6e-07 3MVN-A nrPDB 46 5e-05 1SFF-A nrPDB 36 0.025 2ZUS-A nrPDB 35 0.082 6CR0-A nrPDB 33 0.38 5GT2-A nrPDB 32 0.75 6EAS-A nrPDB 32 0.81 2C41-A nrPDB 31 0.90 6GI9-A nrPDB 31 1.0 3IPI-A nrPDB 31 1.2 6FKT-A nrPDB 29 3.6 2CZH-A nrPDB 29 3.7 3GP8-A nrPDB 28 7.2 1HG3-A nrPDB 28 8.1 >1E8C-A nrPDB Length = 498 Score = 656 bits (1693), Expect = 0.0, Method: Composition-based stats. Identities = 494/494 (100%), Positives = 494/494 (100%) Query: 2 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA 61 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA Sbjct: 1 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVA 60 Query: 62 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT 121 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT Sbjct: 61 AIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKT 120 Query: 122 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA 181 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA Sbjct: 121 TTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCA 180 Query: 182 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA 241 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA Sbjct: 181 MEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINA 240 Query: 242 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES 301 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES Sbjct: 241 DDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIES 300 Query: 302 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT 361 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT Sbjct: 301 HLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHT 360 Query: 362 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP 421 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP Sbjct: 361 PDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP 420 Query: 422 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY 481 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY Sbjct: 421 RAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDY 480 Query: 482 SDRVTVARLLGVIA 495 SDRVTVARLLGVIA Sbjct: 481 SDRVTVARLLGVIA 494 >4C12-A nrPDB Length = 501 Score = 488 bits (1256), Expect = e-138, Method: Composition-based stats. Identities = 145/473 (30%), Positives = 230/473 (48%), Gaps = 25/473 (5%) Query: 19 SRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIRE 78 + + ++T DSR A G +FVA VG+ D ++ QG ++ K+++ + + Sbjct: 20 EQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVN-KEQSLPANVTQ 78 Query: 79 MHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEIS 138 + + S LA Y PS L GVTGTNGKT+ ++ + L + S Sbjct: 79 V------VVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNS 132 Query: 139 AVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALK 198 A +GT G + NTT V + ++ VD GA +EVSSHGLV R+ ++ Sbjct: 133 AYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVE 192 Query: 199 FAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSE-----HHCGQAIINADDEVGRRWLAKL 253 F ++F+NL++DHLD+HG ME Y AK LL+S+ ++N DD Sbjct: 193 FDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVT 252 Query: 254 PDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLL 313 P V D A + G + F + +G ++S +G FN+SN++ Sbjct: 253 PYEVFSYGID------EEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIM 306 Query: 314 LALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAAR 373 A+ + + G L ++K L+PV GR+EV +++DYAHT D + K + A + Sbjct: 307 AAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQ 366 Query: 374 LHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGML 433 KL + G G+RD K P MG +A AD + T DNP ++P+ + ++ G Sbjct: 367 PFVKQKLIFLVGMAGERDLTKTPEMGRVACR-ADYVIFTPDNPANDDPKMLTAELAKG-- 423 Query: 434 DAGHAKVME--GRAEAVTCAVMQAKENDVVLVAGKGHEDYQIV-GNQRLDYSD 483 A H +E RAE + A+ A+ D V++A KG E YQI+ G+ ++ + D Sbjct: 424 -ATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRD 475 >4BUB-A nrPDB Length = 498 Score = 447 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 163/497 (32%), Positives = 249/497 (50%), Gaps = 36/497 (7%) Query: 5 NLRDLL----APWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGV 60 NL+DL+ AP+ + ++ S GDLF+ G + D IP+ + +G Sbjct: 9 NLKDLILEVRAPY-----DLEITGVSNHSSKVKKGDLFICRRGEKFDSHEIIPEVMEKGA 63 Query: 61 AAIIAEAKDEATDGEIREMHGVPVIYLSQLNERL--SALAGRFYHEPSDNLRLVGVTGTN 118 A++ E + Y+ + R + +A F+ +P ++ GVTGTN Sbjct: 64 VAVVVER-----------EIDLDFPYIQVFDSRYFEAKVASLFFEDPWKDVLTFGVTGTN 112 Query: 119 GKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGAT 178 GKTTTT ++ LGE +V+ T +LG + TT A+ + + + G Sbjct: 113 GKTTTTMMIYHMLTSLGERGSVLTTAVKRILGNSYYDDITTPDAITILSAMKENREGGGK 172 Query: 179 FCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSE-HHCGQA 237 F A+EVSSH LVQ RV ++F +FTN+SRDHLD+HG E+Y AK L+ G A Sbjct: 173 FFALEVSSHALVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDDGVA 232 Query: 238 IINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDG 297 ++N LA + + + + N R L EV++ G + G Sbjct: 233 VLNES-------LADAFNRKSRKITFGTSKNADYR-LGNIEVSWE--GTQFVLETPDGLL 282 Query: 298 EIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKP--TVV 355 ++ + +G FN N A+A L LGY DL + V GR EV K VV Sbjct: 283 KVFTRAIGDFNAYNAAAAIAALHQLGYDPKDLASSLETFTGVEGRFEVVRGAKKIGLNVV 342 Query: 356 VDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDN 415 VD+AH+PDALEK L+ R G++ VFG GG+ D+GKRP+M +A + ADV ++T D+ Sbjct: 343 VDFAHSPDALEKLLKNVRKISQGRVIVVFGAGGNSDRGKRPMMSEVASKLADVVILTTDD 402 Query: 416 PRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVG 475 PR E+P I+ D++ G+ V+ R EA+ A+ A D V++AG+GHE YQI+ Sbjct: 403 PRGEDPEQIMEDLIKGIDKRKPYLVLFDRREAIETALTIANRGDSVVIAGRGHERYQIID 462 Query: 476 NQ-RLDYSDRVTVARLL 491 + ++ + DR V ++ Sbjct: 463 EEKKVPFQDREVVEEII 479 >2WTZ-A nrPDB Length = 535 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 185/475 (38%), Positives = 254/475 (53%), Gaps = 21/475 (4%) Query: 20 RALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREM 79 R + +TL ++ + GDLF A+ G G R++ AIA+G A++ D A EI Sbjct: 60 RTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVL---TDPAGVAEIAGR 116 Query: 80 HGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISA 139 VPV+ L LA Y PS+ L ++G+TGT+GKTTTT L+ + G ++ Sbjct: 117 AAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAG 176 Query: 140 VMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKF 199 ++GT+G + G +P+ TT A +Q LA +V++G MEVSSH L RV +F Sbjct: 177 LIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRF 236 Query: 200 AASVFTNLSRDHLDYHGDMEHYEAAKWLLY---SEHHCGQAIINADDEVGRRWLAKLPDA 256 A FTNLSRDHLD+H M Y AK L+ S A++ DD+ GR A+ DA Sbjct: 237 AVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADA 296 Query: 257 VAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDG---EIESHLMGAFNVSNLL 313 + VS D +AT+V D+G +F++ G I L G +NV+N L Sbjct: 297 ITVSAADRPAH------WRATDVAPTDAGGQ-QFTAIDPAGVGHHIGIRLPGRYNVANCL 349 Query: 314 LALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAAR 373 +ALA L +G + ++ V GR+E +VDYAH P+AL L Sbjct: 350 VALAILDTVGVSPEQAVPGLREIR-VPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL- 407 Query: 374 LHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGML 433 H +L VFG GGDRD GKR MG IA + AD+ VVTDDNPR E+P AI +ILAG Sbjct: 408 AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAA 467 Query: 434 D-AGHAKVME--GRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRV 485 + G A+V+E R +A+ AV A+ DVVL+AGKGHE Q G + + DRV Sbjct: 468 EVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRV 522 >3ZL8-A nrPDB Length = 437 Score = 292 bits (748), Expect = 2e-79, Method: Composition-based stats. Identities = 102/448 (22%), Positives = 167/448 (37%), Gaps = 56/448 (12%) Query: 23 REMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGV 82 R L+S+ GD+FVAV G + DG +I +A+ G AIIAE K +D V Sbjct: 7 RRFVLNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIFLVESSV 66 Query: 83 PVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMG 142 + E+L +G +VGVTG++GKTTT ++L LL +V Sbjct: 67 DTLAKLA-REKLGNFSGT----------VVGVTGSSGKTTTKEILY---NLLKNKRSVFK 112 Query: 143 TVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAAS 202 T GN G + + ++ G + M S G + H + Sbjct: 113 TPGNM--------NTEYGLPLSILNDYKG---EEILVLEMAASRPGDIAHLCKIAPPDVA 161 Query: 203 VFTNLSRDHLDYHGDMEHYEAAKW-LLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSM 261 V N+ HL++ G E K ++ A+ DD R+ + + + + Sbjct: 162 VLLNVGSAHLEFFGTRERIMETKMEIIKHSKENAIAVTLFDDPDLRKEVPRYRNTLFFGK 221 Query: 262 E--DHINPN-CHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALAT 318 E D + + + E DS T++ S W G++ N+ +L Sbjct: 222 EGGDSVLKDWWYYEGSTIAEFEAFDSLFTVKLSGYWNGGQL----------LNIAASLCV 271 Query: 319 LLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAG 378 + LG + D+ A L+ V GR V G V Y +P+A + +++A L G Sbjct: 272 MRTLGETV-DIFD-LASLKTVPGRFNVREKKGVLIVDDTYNASPEAFQTSIEAL-LRFPG 328 Query: 379 KLWCVFGCG---GDRDKGKRPLMGAIAEEFADVAVVTDDNPR-----------TEEPRAI 424 K + V G G+R K +G V V + +++P I Sbjct: 329 KKFAVVGAMKELGERSKEFHEELGERLNVLDGVYVFLSEPEAEWIKSKKIILKSDDPEKI 388 Query: 425 INDILAGMLDAGHAKVMEGRAEAVTCAV 452 D+ + RA + + Sbjct: 389 AKDLATRVKKGDVVLFKASRAVRIERVL 416 >4QDI-A nrPDB Length = 472 Score = 270 bits (691), Expect = 7e-73, Method: Composition-based stats. Identities = 89/413 (21%), Positives = 151/413 (36%), Gaps = 64/413 (15%) Query: 13 WVPDA-PSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEA 71 W D P ++ + DSR A +GD F+A+ G + D ++ Q +A G I E Sbjct: 33 WHKDQIPQTEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVE---RP 89 Query: 72 TDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWS 131 D EI + + ++ L L G + E + L+++ +TG++GKTTT ++L Sbjct: 90 IDAEIAQ------LVVADTRLALGQL-GAYRREQNAQLKVIALTGSSGKTTTKEMLG--- 139 Query: 132 QLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQ 191 +L ++ PT T G+ + D G +E+ + Sbjct: 140 ---------------SILSRLAPTLITRGNLNN---------DLGVPMMLLELRK----E 171 Query: 192 HRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQ-----AIINADDEVG 246 H+ A ++ A+ + +DY + A L H G+ I A E+ Sbjct: 172 HQYAVMELGAN-----HQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEIY 226 Query: 247 RRWLAK-----------LPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWG 295 R L + + + I G + ATE+ A + + G Sbjct: 227 RHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGEGGDVFATEIELLPQSANFQLHTPQG 286 Query: 296 DGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVV 355 + G NV N A+A LALG L D++K + Q GR+ + Sbjct: 287 SSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQKAPHLFID 346 Query: 356 VDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADV 408 Y P ++ A Q L G V G G+ + + A++ Sbjct: 347 DTYNANPTSMRAAAQVL-LQQNGIKVMVMGDIGELGDSSWQEHHDLGRDLAEL 398 >4CVK-A nrPDB Length = 475 Score = 235 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 92/374 (24%), Positives = 153/374 (40%), Gaps = 40/374 (10%) Query: 25 MTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPV 84 ++ DSR G+LF+A+ G + DG Y+ + A+G A + E RE+ P+ Sbjct: 28 VSTDSRAIGPGELFIALSGPRFDGHDYLAEVAAKGAVAALVE----------REVADAPL 77 Query: 85 IYLSQLNER-----LSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQL-LGEIS 138 L + R L AL R + P L +TG++GKTT ++LA + G+ Sbjct: 78 PQLLVRDTRAALGRLGALNRRKFTGP-----LAAMTGSSGKTTVKEMLASILRTQAGDAE 132 Query: 139 AVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALK 198 +V+ T GN N G + + + S G + + V + Sbjct: 133 SVLATRGN--------LNNDLGVPLTLLQLAPQHRSA---VIELGASRIGEIAYTVELTR 181 Query: 199 FAASVFTNLSRDHL-DYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAV 257 ++ TN H+ ++ G + EA +L G A++N DD+ W A+ Sbjct: 182 PHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGRP 241 Query: 258 AVSMEDHINPNCHGRWLKATEVNYHDSGAT-IRFSSSWGDGEIESHLMGAFNVSNLLLAL 316 ++ P +A ++ G R G+ +++ +L+G NV+N L A Sbjct: 242 LLTFSLD-RPQAD---FRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAA 297 Query: 317 ATLLALGYPLADLLKTAARLQPVCGR-MEVFTAPGKPTVVVDYAHTPDALEKALQAARLH 375 A ALG PL ++ LQPV GR + TA G + Y P ++ A+ Sbjct: 298 AAAHALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGF 357 Query: 376 CAGKLWCVFGCGGD 389 G+ V G G+ Sbjct: 358 S-GRTVLVLGDMGE 370 >3ZM5-A nrPDB Length = 465 Score = 172 bits (434), Expect = 5e-43, Method: Composition-based stats. Identities = 83/437 (18%), Positives = 150/437 (34%), Gaps = 56/437 (12%) Query: 20 RALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREM 79 L + DSR+ GDLFV + G + DG +I A G A ++E +E+ Sbjct: 24 TQLEKAEFDSRLIGTGDLFVPLKGAR-DGHDFIETAFENGAAVTLSE----------KEV 72 Query: 80 HGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISA 139 P I + + +LA Y+ + + VTG+NGKTTT +LA LL Sbjct: 73 SNHPYILVDDVLTAFQSLAS--YYLEKTTVDVFAVTGSNGKTTTKDMLA---HLLSTRYK 127 Query: 140 VMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSS--HGLVQHRVAAL 197 T GN N G V H +G +E+ G + Sbjct: 128 TYKTQGNY--------NNEIGLPYTVLHMP-----EGTEKLVLEMGQDHLGDIHLLSELA 174 Query: 198 KFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAV 257 + ++ T + HL + D K + G ++ D + +L Sbjct: 175 RPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLP------ 228 Query: 258 AVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALA 317 ++ + G L+ T++ T + +++ + ++ + G +N +N ++A Sbjct: 229 ---IDKKVVRFGQGAELEITDLVERKDSLTFK--ANFLEQALDLPVTGKYNATNAMIASY 283 Query: 318 TLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVD-YAHTPDALEKALQAARLHC 376 L G + L+ R E A ++ D Y P A++ L+ Sbjct: 284 VALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIP 343 Query: 377 A---GKLWCVFGCGGDRDKGKRPLMGAIAEEFA----DVAVVTDDNPRTEEPRAIINDIL 429 A GK V + L + + D+ + E+ + + Sbjct: 344 ANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFY-----GEDIAQL-AQLA 397 Query: 430 AGMLDAGHAKVMEGRAE 446 + M GH + + Sbjct: 398 SQMFPIGHVYYFKKTED 414 >1J6U-A nrPDB Length = 469 Score = 170 bits (429), Expect = 2e-42, Method: Composition-based stats. Identities = 69/296 (23%), Positives = 106/296 (35%), Gaps = 44/296 (14%) Query: 199 FAASVFTNLSRDHLD-YHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAV 257 + TN DHL+ Y + Y +A + + A+DE+ Sbjct: 182 PNYLIITNARGDHLENYGNSLTRYRSAFEKISRNTDL--VVTFAEDELTSHLGDVTFGVK 239 Query: 258 AVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALA 317 + + +A + + E++ + G NV N L +A Sbjct: 240 KGTYTLEMRSA-----SRAEQKAMVEKNGKRYL-------ELKLKVPGFHNVLNALAVIA 287 Query: 318 TLLALGYPLADLLKTAARLQPVCGRMEV-FTAPGKPTVVV-DYAHTPDALEKALQAAR-L 374 +LGY LA +L+ + V R + F P V+ DYAHTPD + LQ A+ + Sbjct: 288 LFDSLGYDLAPVLEALEEFRGVHRRFSIAFHDPETNIYVIDDYAHTPDEIRNLLQTAKEV 347 Query: 375 HCAGKLWCVFG----CGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPR-----AII 425 K+ +F +R+ G A A + AD VVT+ EE + +I Sbjct: 348 FENEKIVVIFQPHRYSRLEREDGN----FAKALQLADEVVVTEVYDAFEEKKNGISGKMI 403 Query: 426 NDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGH---------EDYQ 472 D L + A +E E V+ EN V L G G E YQ Sbjct: 404 WDSLKSL--GKEAYFVEKLPE--LEKVISVSENTVFLFVGAGDIIYSSRRFVERYQ 455 >1GG4-A nrPDB Length = 452 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 76/365 (20%), Positives = 135/365 (36%), Gaps = 31/365 (8%) Query: 21 ALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMH 80 L +T D+R G LFVA+ G + D + QA A G A++ + Sbjct: 23 TLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLD---------I 73 Query: 81 GVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAV 140 +P + + LA R+V +TG++GKT+ ++ A G Sbjct: 74 DLPQLIVKDTRLAFGELAAWVR--QQVPARVVALTGSSGKTSVKEMTAAILSQCGN---T 128 Query: 141 MGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFA 200 + T GN N G + + L + + + G + V+ + Sbjct: 129 LYTAGN--------LNNDIGVPMTL---LRLTPEYDYAVIELGANHQGEIAWTVSLTRPE 177 Query: 201 ASVFTNLSRDHLDYHGDMEHYEAAKWLLY-SEHHCGQAIINADDEVGRRWLAKLPDAVAV 259 A++ NL+ HL+ G + AK ++ G AI+NAD+ W + + Sbjct: 178 AALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSV----IGS 233 Query: 260 SMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATL 319 +PN AT ++ G + G ++ L G N++N L A A Sbjct: 234 RKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALS 293 Query: 320 LALGYPLADLLKTAARLQPVCGRMEVFT-APGKPTVVVDYAHTPDALEKALQAARLHCAG 378 +++G L + A L+ V GR+ A + + Y ++ A+Q Sbjct: 294 MSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGY 353 Query: 379 KLWCV 383 ++ V Sbjct: 354 RVLVV 358 >3LK7-A nrPDB Length = 451 Score = 163 bits (413), Expect = 1e-40, Method: Composition-based stats. Identities = 87/439 (19%), Positives = 145/439 (33%), Gaps = 51/439 (11%) Query: 32 AAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVI------ 85 A G + G D + +G+ + E D + M P I Sbjct: 29 AKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVCGSHPLELLDEDFCYMIKNPGIPYNNPM 88 Query: 86 YLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVG 145 L +++ L +L+G+TG+NGKTTTT ++A+ G+ + G +G Sbjct: 89 VKKALEKQIPVLTEVELAYLVSESQLIGITGSNGKTTTTTMIAEVLNAGGQRGLLAGNIG 148 Query: 146 NGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFT 205 P +A D ME+SS L+ V + +V T Sbjct: 149 -------FPASEVVQAANDKDT------------LVMELSSFQLMG--VKEFRPHIAVIT 187 Query: 206 NLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHI 265 NL HLDYHG E Y AAKW + ++ ++ ++ + LAK A V Sbjct: 188 NLMPTHLDYHGSFEDYVAAKWNIQNQMSSSDFLVLNFNQGISKELAKTTKATIVPFSTTE 247 Query: 266 NPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYP 325 + + G I G + G+ NV N L +A G Sbjct: 248 KVDGAY----VQDKQLFYKGENIMSVDDIG-------VPGSHNVENALATIAVAKLAGIS 296 Query: 326 LADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFG 385 + +T + V R++ + D + +A K+ + Sbjct: 297 NQVIRETLSNFGGVKHRLQSLGKVHGISFYND--SKSTNILATQKALSGFDNTKVILI-- 352 Query: 386 CGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRA 445 G D+G E D+ + E + + A Sbjct: 353 -AGGLDRGN-----EFDELIPDITGLKHMVVLGESASRVKRAAQKAGVTYSDAL---DVR 403 Query: 446 EAVTCAVMQAKENDVVLVA 464 +AV A A++ DV+L++ Sbjct: 404 DAVHKAYEVAQQGDVILLS 422 >2JFH-A nrPDB Length = 445 Score = 131 bits (328), Expect = 8e-31, Method: Composition-based stats. Identities = 72/291 (24%), Positives = 108/291 (37%), Gaps = 46/291 (15%) Query: 107 DNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQ 166 +V +TG+NGK+T T L+ + ++ G V G +G L Sbjct: 103 AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPAL----------------- 145 Query: 167 HELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDMEHYEAAK 225 L+D +E+SS L ++L+ A+ N++ DH+D Y ++ Y AAK Sbjct: 146 ----MLLDDECELYVLELSSFQL--ETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAK 199 Query: 226 WLLYSEHHCGQAIINADDEVGR--RWLAKLPDAVAVSMED-HINPNCHGRWLKATEVNYH 282 +Y ++NADD + R + + V+M D H+N WL+ Sbjct: 200 LRIYENAK--VCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVL 257 Query: 283 DSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGR 342 + E L G N +N L ALA A G P A LK + R Sbjct: 258 NVK--------------EMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHR 303 Query: 343 ME-VFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK 392 E V G + A + E AL H G L + G G Sbjct: 304 FEVVLEHNGVRWINDSKATNVGSTEAALNGL--HVDGTLHLLLGGDGKSAD 352 >3HN7-A nrPDB Length = 524 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 64/388 (16%), Positives = 127/388 (32%), Gaps = 38/388 (9%) Query: 111 LVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELA 170 ++ V GT+GKTTTT +LA G + + + + + + E Sbjct: 124 VIAVAGTHGKTTTTTMLAWILHYAGIDAGFLIGGVPLVNTTDTNLQQVFAHSSYLGTE-K 182 Query: 171 GLVDQGATF--CAMEV----SSHGLVQHRVAALKFAASVFTNLSRDHLD----------- 213 D +E S+ + + + ++ NL DH D Sbjct: 183 DDSDNSVNTGYFVIEADEYDSAFFDKRSKFVHYRPRTAILNNLEFDHADIFADLDAIQTQ 242 Query: 214 YHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRW 273 +H + + ++ A W + D+ S+ +P + + Sbjct: 243 FHHMVRMIPSTGKIIMPAATISLEDTLAKGVWTPIWRTSVIDSTISSVRREDSPLENSQA 302 Query: 274 LKATEVNYH---DSGATIRFSSSWG---DGEIESHLMGAFNVSNLLLALATLLALGYPLA 327 +++ G+ S + + + G NV+N L+A+A +G + Sbjct: 303 ENSSDWQAELISADGSQFTVSFNDNKEATALVNWSMSGLHNVNNALVAIAAAYNIGVSVK 362 Query: 328 DLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAA-RLHCAGKLWCVFGC 386 + + RME+ V D+AH P A+ L A + +LW + Sbjct: 363 TACAALSAFAGIKRRMELIGDVNDILVFDDFAHHPTAITTTLDGAKKKLADRRLWAII-- 420 Query: 387 GGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDA-------GHAK 439 + MG + A A + D+ EP + + + +A G + Sbjct: 421 ---EPRSNTMKMGIHQDSLAQSATLA-DHTLWYEPTGLEWGLKEVIDNATIANPSIGSQQ 476 Query: 440 VMEGRAEAVTCAVMQAKENDVVLVAGKG 467 V+ + + AK D +++ G Sbjct: 477 VLSSVDDIIKHICTHAKAGDAIVIMSNG 504 >6CAU-A nrPDB Length = 472 Score = 95.7 bits (236), Expect = 4e-20, Method: Composition-based stats. Identities = 56/286 (19%), Positives = 100/286 (34%), Gaps = 21/286 (7%) Query: 197 LKFAASVFTNLSRDHLD-YHGDMEHYEAAKWLLYSEHHC-GQAIINADDEVGRRWLAKLP 254 L+ A++ TN+ DH+D Y G + + G A++ DD R L ++ Sbjct: 178 LQPMAAIVTNIDADHMDTYEGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVG 237 Query: 255 DAVAVSMEDHINPNCHGRWLKATEVNYHDSGATI-RFSSSWGDGEIESHLMGAFNVSNLL 313 V ++A +V + + + G NV N L Sbjct: 238 RPVITYG------FNEDNDIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNAL 291 Query: 314 LALATLLALGYPLADLLKTAARLQPVCGRMEV---FTAPGKPT-VVVDYAHTPDALEKAL 369 A+ G + + V R +V F +V DY H P +E + Sbjct: 292 AAIGVATDEGVSDEAISRALKGFSGVGRRFQVQGEFELGEGNVKLVDDYGHHPKEVEATI 351 Query: 370 QAAR-LHCAGKLWCVFGC-GGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEP--RAII 425 +AAR H +L +F R + + + D ++ + P E+P A Sbjct: 352 KAARQSHPDRRLVMLFQPHRYSRTRDCFDDFIEVLSQV-DQLLLLEVYPAGEKPIVGADS 410 Query: 426 NDILAGMLDAGHAK-VMEGRAEAVTCAVMQ--AKENDVVLVAGKGH 468 + + G + ++ E +MQ + ND++L G G+ Sbjct: 411 RTLARSIRLRGQVEPILIDPVEGNLQNIMQNVLQPNDLLLTQGAGN 456 >4HV4-A nrPDB Length = 494 Score = 94.2 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 79/462 (17%), Positives = 140/462 (30%), Gaps = 65/462 (14%) Query: 39 VAVVGHQADGRRYIPQAIAQ-----GVAAIIAEAKDEATDGEIREMH---GVPVIYLSQL 90 +A G+Q G P ++ Q G + D + + + Sbjct: 42 LANEGYQISGSDLAPNSVTQHLTALGAQIYFHHRPENVLDASVVVVSTAISADNPEIVAA 101 Query: 91 NE-------RLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGT 143 E R LA + + V GT+GKTTTT +L+ G Sbjct: 102 REARIPVIRRAEMLAELMRYRHG-----IAVAGTHGKTTTTAMLSSIYAEAGLDPTF--- 153 Query: 144 VGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASV 203 + G ++ T ++ +A + A+F + + ++ Sbjct: 154 ----VNGGLVKAAGTHARLGSSRYLIAEADESDASFLHL---------------QPMVAI 194 Query: 204 FTNLSRDHLD-YHGDMEHYEAAKWLLYSEHHC-GQAIINADDEVGRRWLAKLPDAVAVSM 261 TN+ DH+D Y GD E+ + G+A++ DD V R L ++ + Sbjct: 195 VTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYG 254 Query: 262 EDHINPNCHGRWLKATEVNYHDSGATIRFSSSW-GDGEIESHLMGAFNVSNLLLALATLL 320 ++ E+ + G N N A+A Sbjct: 255 ------FSDDADVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNALNAAAAVAVAT 308 Query: 321 ALGYPLADLLKTAARLQPVCGRMEVF---------TAPGKPTVVVDYAHTPDALEKALQA 371 G D+L+ Q R + G +V DY H P ++ ++A Sbjct: 309 EEGIEDEDILRALVGFQGTGRRFDFLGNFPLAPVNGKEGSAMLVDDYGHHPTEVDATIKA 368 Query: 372 ARL-HCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEE--PRAIINDI 428 AR ++ +F A DV ++ D E P A + Sbjct: 369 ARAGWPDKRIVMLFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEPPIPGADSRAL 428 Query: 429 LAGMLDAG--HAKVMEGRAEAVTCAVMQAKENDVVLVAGKGH 468 + + G ++ A D++LV G G+ Sbjct: 429 CRTIRNRGKLDPILVPDSESAPEMLAQILNGEDLILVQGAGN 470 >2F00-A nrPDB Length = 491 Score = 90.3 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 63/374 (16%), Positives = 116/374 (31%), Gaps = 45/374 (12%) Query: 112 VGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAG 171 + + GT+GKTTTT +++ G + G ++ ++ +A Sbjct: 122 IAIAGTHGKTTTTAMVSSIYAEAGLDPTF-------VNGGLVKAAGVHARLGHGRYLIAE 174 Query: 172 LVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDMEHYEAAKWLLYS 230 + A+F + + ++ TN+ DH+D Y GD E+ + Sbjct: 175 ADESDASFLHL---------------QPMVAIVTNIEADHMDTYQGDFENLKQTFINFLH 219 Query: 231 EHHC-GQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIR 289 G+A++ DD V R L ++ ++ + Sbjct: 220 NLPFYGRAVMCVDDPVIRELLPRVGRQTTTYG------FSEDADVRVEDYQQIGPQGHFT 273 Query: 290 FSSSWGD-GEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVF-- 346 + + + G N N A+A G +L+ Q R + Sbjct: 274 LLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGE 333 Query: 347 -------TAPGKPTVVVDYAHTPDALEKALQAARL-HCAGKLWCVFGCGGDRDKGKRPLM 398 G +V DY H P ++ ++AAR L +F Sbjct: 334 FPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDD 393 Query: 399 GAIAEEFADVAVVTDDNPRTEE--PRAIINDILAGMLDAG--HAKVMEGRAEAVTCAVMQ 454 A D ++ + P E P A + + G ++ A Sbjct: 394 FANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEMLAPV 453 Query: 455 AKENDVVLVAGKGH 468 ND++LV G G+ Sbjct: 454 LTGNDLILVQGAGN 467 >1GQY-A nrPDB Length = 475 Score = 87.3 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 67/374 (17%), Positives = 119/374 (31%), Gaps = 49/374 (13%) Query: 58 QGVAAIIAEA--KDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVT 115 +G + ++ + KD+ + + +PVI +Q+ + + V Sbjct: 76 EGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHG-----------IAVA 124 Query: 116 GTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQ 175 GT+GKTTTT +++ + G ++ + ++ +A + Sbjct: 125 GTHGKTTTTAMISMIYTQAKLDPTF-------VNGGLVKSAGKNAHLGASRYLIAEADES 177 Query: 176 GATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLD-YHGDMEHYEAAKWLLYSEHHC 234 A+F + + SV TN+ DH+D Y GD E +A Sbjct: 178 DASFLHL---------------QPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPF 222 Query: 235 -GQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSS 293 G A++ ADD V + K+ V + + Sbjct: 223 YGLAVMCADDPVLMELVPKVGRQVITYG------FSEQADYRIEDYEQTGFQGHYTVICP 276 Query: 294 WGD-GEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRM----EVFTA 348 + + ++ G N N ALA G +L+ A Q R E Sbjct: 277 NNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRP 336 Query: 349 PGKPTVVVDYAHTPDALEKALQAARL-HCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFAD 407 GK +V DY H P + ++AAR ++ +F D Sbjct: 337 NGKVRLVDDYGHHPTEVGVTIKAAREGWGDKRIVMIFQPHRYSRTRDLFDDFVQVLSQVD 396 Query: 408 VAVVTDDNPRTEEP 421 ++ D E P Sbjct: 397 ALIMLDVYAAGEAP 410 >4BUC-A nrPDB Length = 450 Score = 86.1 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 66/391 (16%), Positives = 123/391 (31%), Gaps = 67/391 (17%) Query: 101 FYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTG 160 F+ + D ++VG+TGT+GK+T T L+ G + + G G Sbjct: 114 FFLDNVDPKKVVGITGTDGKSTATALMYHVLSGRGFKTFLGGNFG--------------- 158 Query: 161 SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVF--TNLSRDHLDYHGDM 218 ++ + +E+SS L + S F N+S DHLD+H Sbjct: 159 ------TPAVEALEGEYDYYVLEMSSFQLFWSE----RPYLSNFLVLNISEDHLDWHSSF 208 Query: 219 EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATE 278 + Y +K A + + ++ + P ATE Sbjct: 209 KEYVDSKL--------KPAFLQTEGDLFVYNKHIERLRNLEGVRSRKIPFWTDENF-ATE 259 Query: 279 VNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQP 338 G G+ + N+L + + L L+ +P Sbjct: 260 KELIVRGKKYTLP---GNYPYQMR-------ENILAVSVLYMEMFNELESFLELLRDFKP 309 Query: 339 VCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLM 398 + RME D T + L A + CG + + + Sbjct: 310 LPHRMEYLGQIDGRHFYNDSKAT--STHAVLGALSNFDK---VVLIMCGIGKKENYSLFV 364 Query: 399 GAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKEN 458 + + + + + I+ LA + ++E EA A+ +++ Sbjct: 365 EKASPKLKHLIMFGE-----------ISKELAPFVGKIPHSIVENMEEAFEKAMEVSEKG 413 Query: 459 DVVLVAGKG-----HEDYQIVGNQRLDYSDR 484 DV+L++ G +E+Y G + R Sbjct: 414 DVILLSPGGASFDMYENYAKRGEHFREIFKR 444 >5VVW-A nrPDB Length = 315 Score = 74.9 bits (182), Expect = 6e-14, Method: Composition-based stats. Identities = 51/304 (16%), Positives = 99/304 (32%), Gaps = 43/304 (14%) Query: 44 HQADGRRYIPQAIAQ--GVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRF 101 + + +I G ++ + + E+ + + R LA Sbjct: 50 EKFGAQIFIGHQAENADGADVLVVSSAINRANPEVASALERRIPVVP----RAEMLAELM 105 Query: 102 YHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGS 161 + + V GT+GKTTTT L+A G ++G + T Sbjct: 106 RYRHG-----IAVAGTHGKTTTTSLIASVFAAGGLDPTF-------VIGGRLNAAGTNAQ 153 Query: 162 AVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHL-DYHGDMEH 220 ++ +A + A+F + + +V TN+ DH+ Y GD Sbjct: 154 LGASRYLVAEADESDASFLHL---------------QPMVAVVTNIDADHMATYGGDFNK 198 Query: 221 YEAA-KWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEV 279 + L++ G A++ DD V R L ++ V+ ++A + Sbjct: 199 LKKTFVEFLHNLPFYGLAVMCVDDPVVREILPQIA-RPTVTYGLS-----EDADVRAINI 252 Query: 280 NYHDSGATIRFSSSWGD-GEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQP 338 + ++ ++ G NV N L + G +++ + Q Sbjct: 253 RQEGMRTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIVQGLSGFQG 312 Query: 339 VCGR 342 V GR Sbjct: 313 V-GR 315 >6H5E-B nrPDB Length = 437 Score = 72.6 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 57/307 (18%), Positives = 97/307 (31%), Gaps = 50/307 (16%) Query: 110 RLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHEL 169 +V ++GTNGKTTT+ L+ + ++ + I + S + + Sbjct: 49 DIVFISGTNGKTTTSNLIGHTLKA--NNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAV 106 Query: 170 AGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLY 229 + + EV+ + VFTN RD +D G+++ Sbjct: 107 IEIDEGSIPRVLKEVT-------------PSMMVFTNFFRDQMDRFGEIDIMVNNIAETI 153 Query: 230 SEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCH------------GRWLKAT 277 S ++NADD R V M+ H + GR L+ Sbjct: 154 SNKGIKL-LLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYD 212 Query: 278 EVNYHDSG---ATIRFSSSWGDGEIES------------------HLMGAFNVSNLLLAL 316 ++Y+ G F EI S + G FN N L A Sbjct: 213 YIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAY 272 Query: 317 ATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHC 376 L LG + GRM+ F + +++ A P + +L Sbjct: 273 TVLRELGLNEQTIKNGFETYTSDNGRMQYF-KKERKEAMINLAKNPAGMNASLSVGEQLE 331 Query: 377 AGKLWCV 383 K++ + Sbjct: 332 GEKVYVI 338 >3EAG-A nrPDB Length = 326 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 44/234 (18%), Positives = 75/234 (32%), Gaps = 20/234 (8%) Query: 111 LVGVTGTNGKTTTTQLLAQWSQLLGEISAVM--GTVGNGLLGKVIPTENTTGSAVDVQHE 168 ++GV GT+GKTTT +LA + G + G N + +P + Sbjct: 110 VLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFGVSARLP-QTPRQDPNSQSPF 168 Query: 169 LAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAA-KWL 227 D+ T + S + +V NL DH D D+ + +L Sbjct: 169 FVIEADEYDTAFFDKRSKFVH-------YRPRTAVLNNLEFDHADIFADLGAIQTQFHYL 221 Query: 228 LYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGAT 287 + + G + N + + L K + +A E N D Sbjct: 222 VRTVPSEGLIVCNGRQQSLQDTLDKGCWTP-------VEKFGTEHGWQAGEANA-DGSFD 273 Query: 288 IRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCG 341 + G ++ LMG N N L +A +G + + + V Sbjct: 274 VLLDG-KTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKR 326 >6FQB-A nrPDB Length = 465 Score = 60.3 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 61/308 (19%), Positives = 100/308 (32%), Gaps = 54/308 (17%) Query: 107 DNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQ 166 N +V VTGTNGKT TT L ++ V +L TG A Sbjct: 64 KNYEIVVVTGTNGKTLTTAL----------TVGILKEVYGQVLTNPSGANMITGIATTFL 113 Query: 167 HELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKW 226 + + ++ +S + ++ + V TN+ RD +D G E Y Sbjct: 114 TAKSSKTGKNIAVLEIDEASLSRI---CDYIQPSLFVITNIFRDQMDRFG--EIYTTYNM 168 Query: 227 LLYSEHHCGQA--IINADDEVGRR------------WLAKLPDAVAVSMEDHINPN---- 268 +L + A ++N D + + L K P +A + I Sbjct: 169 ILDAIRKVPTATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQG 228 Query: 269 ----------------CHGRWLKATEVNY----HDSGATIRFSSSWGDGEIESHLMGAFN 308 C G K +++Y R E + G +N Sbjct: 229 ILKYEHNTYANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYN 288 Query: 309 VSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKA 368 + N L A+A LG + + + + V GR E F K +V P +A Sbjct: 289 IYNALAAVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLV-LIKNPVGATQA 347 Query: 369 LQAARLHC 376 ++ +L Sbjct: 348 IEMIKLAP 355 >1FGS-A nrPDB Length = 428 Score = 57.6 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 56/345 (16%), Positives = 111/345 (32%), Gaps = 33/345 (9%) Query: 76 IREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLG 135 + +H P + + + R+ L P R + VTGTNGK + +A + G Sbjct: 7 VAYIHSFPRLAKTGDHRRILTLLHAL-GNPQQQGRYIHVTGTNGKGSAANAIAHVLEASG 65 Query: 136 EISAVMGTV-------GNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHG 188 + + + + IP + V+ L L Q A F E Sbjct: 66 LTVGLYTSPFIMRFNERIMIDHEPIPDAALVNAVAFVRAALERLQQQQADFNVTEFEFIT 125 Query: 189 LVQH------RVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINAD 242 + + +V + + ++ E A H AI Sbjct: 126 ALAYWYFRQRQVDVAVIEVGIGGDTDSTNVITPVVSVLTEVALDHQKLLGHTITAIAKHK 185 Query: 243 DEVGRRWLAKLPDAVA---VSMEDHINPNCHGRWLK------ATEVNYHDSGATIRFSSS 293 + +R + + + ++ +WL+ + H G + Sbjct: 186 AGIIKRGIPVVTGNLVPDAAAVVAAKVATTGSQWLRFDRDFSVPKAKLHGWGQRFTYEDQ 245 Query: 294 WGD-GEIESHLMGAFNVSNLLLALATLLALG------YPLADLLKTAARLQPVCGRMEVF 346 G ++E L+G + N+ +A+ T ++ + A R+E Sbjct: 246 DGRISDLEVPLVGDYQQRNMAIAIQTAKVYAKQTEWPLTPQNIRQGLAASHW-PARLEKI 304 Query: 347 TAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRD 391 + P +V+D AH PD + + A + + + + G D+D Sbjct: 305 SD--TPLIVIDGAHNPDGINGLITALKQLFSQPITVIAGILADKD 347 >2VOR-A nrPDB Length = 487 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 74/419 (17%), Positives = 126/419 (30%), Gaps = 56/419 (13%) Query: 83 PVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMG 142 P + R+SAL P + + + GTNGKT+ +++ L + Sbjct: 39 PETRIDPSLTRISALMDLL-GSPQRSYPSIHIAGTNGKTSVARMVDALVTALHRRTGRTT 97 Query: 143 TV------------GNGLLGKVIPTENTTGSAVDVQHELAGLVDQG-------------- 176 + G + + + G Sbjct: 98 SPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTA 157 Query: 177 ----------ATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHG-DMEHYEAAK 225 +EV G + +V T +S DH+DY G D+ K Sbjct: 158 MAFAAFADAPVDVAVVEVGMGGRWDAT-NVINAPVAVITPISIDHVDYLGADIAGIAGEK 216 Query: 226 WLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSG 285 + + G A +GR+ + +A S+ + G Sbjct: 217 AGIITRAPDGSPDTVA--VIGRQVPKVMEVLLAESVRADASVAREDSEFAVLRRQIAVGG 274 Query: 286 ATIRFSSSWGDG-EIESHLMGAFNVSNLLLALATLLA-LGYPLA-----DLLKTAARLQP 338 ++ G +I L G N +LALA++ A G D ++ Sbjct: 275 QVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQLDGDAVRAGFAAVT 334 Query: 339 VCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWC-VFGCGGDRDKGKRPL 397 GR+E + PTV +D AH P Q + V GD+D + Sbjct: 335 SPGRLERMRSA--PTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDV--DGI 390 Query: 398 MGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGH-AKVMEGRAEAVTCAVMQA 455 + A+ F V V + +PR + A+ + AG + E +A+ A Sbjct: 391 LAALEPVFDSVVVTHNGSPRALDVEALA--LAAGERFGPDRVRTAENLRDAIDVATSLV 447 >3MVN-A nrPDB Length = 163 Score = 45.7 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 49/132 (37%), Gaps = 10/132 (7%) Query: 339 VCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHC-AGKLWCVFGCGGDRDK-GKRP 396 R+EV TV D+AH P A+ + A R ++ V + K G Sbjct: 24 AQRRLEVKGVVNNITVYDDFAHHPTAITATIDALRAKVGQQRILAVLEPRSNTMKMGVHK 83 Query: 397 LMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLD-AGHAKVMEGRAEAVTCAVMQA 455 A + + AD + +P I + + + A A + E V V QA Sbjct: 84 HELATSLQDADSVFIY-------QPPTIEWQVSEVLANLAQPAISADDVDELVMRIVQQA 136 Query: 456 KENDVVLVAGKG 467 K ND +L+ G Sbjct: 137 KPNDHILIMSNG 148 >1SFF-A nrPDB Length = 426 Score = 36.4 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 46/137 (33%), Gaps = 13/137 (9%) Query: 313 LLALATLLALGYPLA-----DLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEK 367 L + +G + L V GR EV A + YA P A Sbjct: 248 TGTLFAMEQMGVAPDLTTFAKSIAGGFPLAGVTGRAEVMDAVAPGGLGGTYAGNPIACVA 307 Query: 368 ALQAARLHCAGKLWCVFGCGGDRDKG-------KRPLMGAIAEEFADVAV-VTDDNPRTE 419 AL+ ++ L G + K K P +G + A +A+ + +D + Sbjct: 308 ALEVLKVFEQENLLQKANDLGQKLKDGLLAIAEKHPEIGDVRGLGAMIAIELFEDGDHNK 367 Query: 420 EPRAIINDILAGMLDAG 436 + +I+A D G Sbjct: 368 PDAKLTAEIVARARDKG 384 >2ZUS-A nrPDB Length = 759 Score = 34.9 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 48/157 (30%), Gaps = 35/157 (22%) Query: 8 DLLAPWVPDAPSRALREMTL-------------DSRVA-----------AAGDLFVAVVG 43 D W+ D+P + T +V A D F A G Sbjct: 194 DTFEQWLKDSPQTDVVRFTTFFYQFTLLFDEKRREKVVDWFGCACTVSPRALDDFEAKYG 253 Query: 44 HQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYH 103 ++ ++ + +A+ + D + V L+ ++ A F Sbjct: 254 YRLRPEDFVDGGAYNSAWRVPRKAQRDWID-FLSGFVRENVKQLADMSHAAGKEAMMFLG 312 Query: 104 EPS----------DNLRLVGVTGTNGKTTTTQLLAQW 130 + D L L V G+ G TTT+++A Sbjct: 313 DQWIGTEPYKDGFDELGLDAVVGSIGDGTTTRMIADI 349 >6CR0-A nrPDB Length = 440 Score = 32.6 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 43/150 (28%), Gaps = 14/150 (9%) Query: 231 EHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRF 290 + G + AD V R L V + P E GA + Sbjct: 239 QTDNGVTVTLADKRVFRALTCVLTLPTKVYADVRFEPPLPPEKRAFIEHAEMADGAELYV 298 Query: 291 SSSWGDGEIESHLMGAFNVSNLLLALATLLALGY------------PLADLLKTAARLQP 338 G + N N + A LG L + AA ++ Sbjct: 299 HVRQNLGNTFT-FCDDPNPFNAVQTYAYDDELGTILKITIGRQSLINLENFDAIAAEIRK 357 Query: 339 VCGRMEVFTAPGKPTVVVDYAHTP-DALEK 367 + G +EV A + +YA T A+ K Sbjct: 358 IHGDVEVLEALPYNWAMDEYARTSYPAMRK 387 >5GT2-A nrPDB Length = 307 Score = 31.8 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 26/68 (38%), Gaps = 1/68 (1%) Query: 413 DDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQ 472 +NP EE R + I G+ G ++ R E + + +D ++ G+ E + Sbjct: 145 TENPAGEETRREVAVIKDGVDAGGSYVFVQ-RWEHNLKQLNRMSVHDQEMMIGRTKEANE 203 Query: 473 IVGNQRLD 480 + Sbjct: 204 EIDGDERP 211 >6EAS-A nrPDB Length = 308 Score = 31.8 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 33/176 (18%), Positives = 61/176 (34%), Gaps = 22/176 (12%) Query: 249 WLAKLPDAVAVSM----EDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLM 304 W+A+L ++ ++ + R +T V D F++ D E + Sbjct: 144 WMARLRISMGIAYCLEHMHQLQTPAALRNFDSTTVYLTD-----DFAAKVSDLEFWNDAK 198 Query: 305 GAFNVSNLLLALATLLALGYPLADLLK--TAARLQPVCGRMEVFTAPGKP-TVVVDYAHT 361 G + +N LA + + D+++ L+ + GR+ G V Y Sbjct: 199 GHNSTTNNELAFSP------DMEDIVRKYGMVLLEILTGRVPSSEDDGPLENWVSRYFEG 252 Query: 362 PDALEKALQAARLHCA----GKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTD 413 LE+ + + L V DRD KRP M +A ++ + Sbjct: 253 GMRLEELIDPSIGFFPEDTARALCEVVRSCIDRDPKKRPQMKEVAARMREITALGP 308 >2C41-A nrPDB Length = 158 Score = 31.4 bits (69), Expect = 0.90, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 27/54 (50%) Query: 76 IREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQ 129 E + +L ER L G+ +P+D L++ VT ++G+ T Q++ + Sbjct: 48 FEEQGSEVFAMIDELAERSLMLDGQPVADPADYLKVATVTPSSGQLTVKQMIEE 101 >6GI9-A nrPDB Length = 373 Score = 31.4 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 38/267 (14%), Positives = 85/267 (31%), Gaps = 35/267 (13%) Query: 17 APSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEI 76 AP+R R GD+ ++G Q +A + ++ + Sbjct: 17 APNRVFMAPLTRLRSIEPGDIPTPLMGEYY----------RQRASAGLIISEATQISAQA 66 Query: 77 REMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTT----TQLLAQWSQ 132 + G P ++ + + + E + TG ++ ++ + Sbjct: 67 KGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRLSHSSIQPGGQAPVSASAL 126 Query: 133 LLGEISAVMGTVGNGL-----LGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSH 187 +++ GN + + + + G D + +A + G + S+H Sbjct: 127 NANTRTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFDLVELH-SAH 185 Query: 188 GLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGR 247 G + H+ S +N D Y G +E+ A+ +L A+ N R Sbjct: 186 GYLLHQF------LSPSSNQRTDQ--YGGSVEN--RARLVL----EVVDAVCNEWSAD-R 230 Query: 248 RWLAKLPDAVAVSMEDHINPNCHGRWL 274 + P ++++ N +L Sbjct: 231 IGIRVSPIGTFQNVDNGPNEEADALYL 257 >3IPI-A nrPDB Length = 295 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 321 ALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCA 377 ALG + L+ V G+ FT+ P + + +AL+K++ +LH A Sbjct: 198 ALGTAYQIVDDILEFLEVVEGKESKFTSETLPHIYMKSTSKEEALKKSIDCVKLHVA 254 >6FKT-A nrPDB Length = 303 Score = 29.5 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 25/68 (36%), Gaps = 1/68 (1%) Query: 413 DDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQ 472 +NP EE R + I G+ G ++ R E + + D ++ G+ + + Sbjct: 148 TENPAGEETRREVAVIKDGVDAGGSYVFVQ-RWEHNLKQLNRMSVPDQEMMIGRTKDANE 206 Query: 473 IVGNQRLD 480 + Sbjct: 207 EIDGDERP 214 >2CZH-A nrPDB Length = 299 Score = 29.5 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 46/124 (37%), Gaps = 10/124 (8%) Query: 2 ADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIP-QAIAQGV 60 A + +R L + + ++ ++ DL ++ + + R+I +A A G Sbjct: 41 AGQIIRKALTEEKRVSTKTSAADLVTETDHLVE-DLIISELRERFPSHRFIAEEAAASGA 99 Query: 61 AAIIAEAKD---EATDGEIREMHGVPVIYLSQLNERLSALA-GRFYHEPSDNLRLVGVTG 116 ++ + + DG +H P + +S L G YH + L TG Sbjct: 100 KCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERL----YTG 155 Query: 117 TNGK 120 G+ Sbjct: 156 RRGR 159 >3GP8-A nrPDB Length = 574 Score = 28.3 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 42/191 (21%), Positives = 61/191 (31%), Gaps = 21/191 (10%) Query: 37 LFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSA 96 LF A +GR Y+P + AT + G + + + + Sbjct: 134 LFAAEAAATGEGRIYLPHVLRAEKKLASLIRTLLATPP--ADGAGNDDWAVPKKARKGLS 191 Query: 97 LAGRFYHEPSDNLRLVGVTGT--NGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIP 154 + RLV +TG GK+TTT+ +A ++ LG + G Sbjct: 192 EEQASVLDQLAGHRLVVLTGGPGTGKSTTTKAVADLAESLGLEVGLCAPTGKAARR---- 247 Query: 155 TENTTGSAVDVQHELAGLVDQGA-----------TFCAMEVSSHG--LVQHRVAALKFAA 201 TG H L G QG EVS G L+ +AA+ A Sbjct: 248 LGEVTGRTASTVHRLLGYGPQGFRHNHLEPAPYDLLIVDEVSMMGDALMLSLLAAVPPGA 307 Query: 202 SVFTNLSRDHL 212 V D L Sbjct: 308 RVLLVGDTDQL 318 >1HG3-A nrPDB Length = 225 Score = 28.3 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 27/74 (36%), Gaps = 7/74 (9%) Query: 360 HTPDALEKALQAARLHCAG-KLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRT 418 P+ + ++ + K+ C G D K +G + A + Sbjct: 158 AKPEVITNTVELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGVT------KA 211 Query: 419 EEPRAIINDILAGM 432 ++P I D+++G+ Sbjct: 212 KDPEKAIWDLVSGI 225 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.115 0.264 Lambda K H 0.267 0.0355 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,829,309 Number of Sequences: 36641 Number of extensions: 534998 Number of successful extensions: 1857 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1700 Number of HSP's gapped (non-prelim): 89 length of query: 495 length of database: 10,336,785 effective HSP length: 101 effective length of query: 394 effective length of database: 6,636,044 effective search space: 2614601336 effective search space used: 2614601336 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.3 bits)