BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P22141 (198 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FGE-J nrPDB 405 e-114 3WXR-K nrPDB 403 e-113 5LF3-J nrPDB 177 3e-45 5FMG-K nrPDB 123 5e-29 3IPM-H nrPDB 83 8e-17 3H4P-a nrPDB 74 5e-14 5FMG-I nrPDB 70 5e-13 5MPC-h nrPDB 68 3e-12 6HEC-1 nrPDB 65 3e-11 3UNH-H nrPDB 60 9e-10 5L4G-8 nrPDB 59 1e-09 6HUB-H nrPDB 59 1e-09 6AVO-C nrPDB 59 2e-09 6EPF-2 nrPDB 58 3e-09 3UNF-K nrPDB 58 3e-09 3NZW-K nrPDB 57 4e-09 3H4P-A nrPDB 56 1e-08 5FGI-H nrPDB 55 1e-08 5CZ8-K nrPDB 55 2e-08 6AVO-B nrPDB 55 2e-08 5L5A-K nrPDB 55 2e-08 5FMG-E nrPDB 55 2e-08 5FMG-L nrPDB 51 3e-07 4Y8P-I nrPDB 50 6e-07 6HV7-H nrPDB 50 8e-07 5FMG-C nrPDB 49 9e-07 4YA5-C nrPDB 49 1e-06 3UNE-I nrPDB 48 3e-06 6EPC-1 nrPDB 46 1e-05 5FMG-N nrPDB 45 2e-05 5LF6-M nrPDB 45 3e-05 5GJQ-g nrPDB 44 3e-05 5LEZ-N nrPDB 44 3e-05 5GJQ-a nrPDB 44 4e-05 6EPE-7 nrPDB 42 1e-04 5GJR-F nrPDB 42 1e-04 5LEZ-C nrPDB 41 4e-04 6HE5-A nrPDB 39 0.001 5FMG-M nrPDB 38 0.003 1G0U-D nrPDB 37 0.007 4FZC-A nrPDB 36 0.011 5FMG-J nrPDB 35 0.014 3NZW-E nrPDB 35 0.015 3NZW-L nrPDB 35 0.018 1T6M-A nrPDB 32 0.13 5T0I-L nrPDB 30 0.53 5LIE-A nrPDB 29 1.6 3SI9-A nrPDB 28 2.4 1R1N-A nrPDB 28 2.5 6J30-C nrPDB 28 3.1 2AF0-A nrPDB 28 3.4 6FVW-g nrPDB 28 3.8 4NZ0-A nrPDB 27 4.0 5GM6-a nrPDB 27 4.5 4ECK-A nrPDB 27 4.5 5T0L-A nrPDB 27 4.6 5FGG-F nrPDB 27 5.1 1D5A-A nrPDB 27 5.1 4PV4-A nrPDB 27 5.1 3K30-A nrPDB 27 8.0 >5FGE-J nrPDB Length = 198 Score = 405 bits (1041), Expect = e-114, Method: Compositional matrix adjust. Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI Sbjct: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID Sbjct: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 181 VKIVDKDGIRQVDDFQAQ 198 VKIVDKDGIRQVDDFQAQ Sbjct: 181 VKIVDKDGIRQVDDFQAQ 198 >3WXR-K nrPDB Length = 238 Score = 403 bits (1036), Expect = e-113, Method: Compositional matrix adjust. Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI Sbjct: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID Sbjct: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 181 VKIVDKDGIRQVDDFQAQ 198 VKIVDKDGIRQVDDFQAQ Sbjct: 181 VKIVDKDGIRQVDDFQAQ 198 >5LF3-J nrPDB Length = 201 Score = 177 bits (449), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 87/194 (44%), Positives = 128/194 (65%), Gaps = 1/194 (0%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 M+ ++GI+ D V++AS + I +KD DK ++S L+ GEAGDTVQFAEYI Sbjct: 1 MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Q N+QLY +R YELSP A ++F R+ LA +RSR PY VN+L+ GYD+ + P LY +D Sbjct: 61 QKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEG-PALYYMD 119 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YL + P+ AHGY F T S+LD +Y P ++ E ++LL+ C++EL+KR ++ Sbjct: 120 YLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFS 179 Query: 181 VKIVDKDGIRQVDD 194 V+I+DK+GI +D+ Sbjct: 180 VRIIDKNGIHDLDN 193 >5FMG-K nrPDB Length = 195 Score = 123 bits (309), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 62/175 (35%), Positives = 102/175 (58%), Gaps = 3/175 (1%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDD-KTRQLSPHTLMSFAGEAGDTVQFAEY 59 MD ++G+R + V+LA+ I LK+ D+ K + + + G GD +QF E+ Sbjct: 1 MDTLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEF 60 Query: 60 IQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 I+ N+ LY + + ++ ++ + F R+ LA +R R P++VN LI GYDKK + +LY Sbjct: 61 IRKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLR-RNPFEVNCLIAGYDKK-DGYQLYWC 118 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPM 174 DYL + GAHGY + ++LD +Y ++T +E LD+ KLC +EL+KR + Sbjct: 119 DYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLL 173 >3IPM-H nrPDB Length = 217 Score = 83.2 bits (204), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 87/167 (52%), Gaps = 5/167 (2%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI ++D+VI+A+ + VT ++ + K Q+ +T M+ AG GD Y++A + Sbjct: 12 VGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYMKAEL 71 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 +LY ++ + +AV++ + L + PY V +L+GG D P ++ ID G Sbjct: 72 ELYRLQRRVNMPIEAVATLLSNMLNQV--KYMPYMVQLLVGGID---TAPHVFSIDAAGG 126 Query: 125 KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKR 171 VE Y + G + + +L+ Y MT +EG+DL+ + ++R Sbjct: 127 SVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQR 173 >3H4P-a nrPDB Length = 219 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 92/197 (46%), Gaps = 8/197 (4%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 M +G+ D+VILA+ K + G V K ++ + M+ AG GD + Sbjct: 1 MTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGGYDKKKNKPELYQ 118 A +LY +R + P A ++ L+ + S R P+ ++IGGYD + +L+ Sbjct: 61 IAEAKLYKMRTGRNIPPLACATL----LSNILHSSRMFPFLTQIIIGGYDLLEG-AKLFS 115 Query: 119 IDYL-GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 +D L G E + A G + +L+ Y DM+ EEG+ L ++ +R Sbjct: 116 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 175 Query: 178 GVIVKIVDKDGIRQVDD 194 G+ + ++ KDG++ +D Sbjct: 176 GISLAVITKDGVKIFED 192 >5FMG-I nrPDB Length = 229 Score = 70.5 bits (171), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 48/159 (30%), Positives = 79/159 (49%), Gaps = 7/159 (4%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ Q++VIL + T G V + K +S + + AG AGD ++Q N Sbjct: 3 ICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQHN 62 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVN-VLIGGYDKKKNKPELYQIDYL 122 ++L+ + + + S + QEL K + Y+V +++GG D N P+LY I Sbjct: 63 VELHRLNTNTQPRVSMCVSRLTQELFK----YQGYKVCAIVLGGVDV--NGPQLYGIHPH 116 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 G+ LP+ A G ++L+ YR +MT EEG +L+ Sbjct: 117 GSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLV 155 >5MPC-h nrPDB Length = 215 Score = 67.8 bits (164), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 76/159 (47%), Gaps = 5/159 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I+ + +D VIL + T G + DK ++ +G A DT A+ +Q + Sbjct: 22 IMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYH 81 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++LY+ + + A S F +EL ++ +++ GYD K NK E+Y I G Sbjct: 82 LELYTSQYGTPSTETAASVF--KELC--YENKDNLTAGIIVAGYDDK-NKGEVYTIPLGG 136 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 + +LPY G + + D ++R +M+ EE +D +K Sbjct: 137 SVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIK 175 >6HEC-1 nrPDB Length = 202 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 87/185 (47%), Gaps = 6/185 (3%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +G+ +D V++A+ K T G + + K Q++ M+ AG GD A I+ Sbjct: 4 VGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIKIEA 63 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 LY IR + + + +A+++ L S R PY V +LIGG D + +Y ID +G Sbjct: 64 NLYEIRRERKPTVRAIATLT-SNLLNSYR-YFPYLVQLLIGGIDSEGKS--IYSIDPIGG 119 Query: 125 KVELP-YGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV-IVK 182 +E A G + +L+ + P++ +E ++L + KR G+ +VK Sbjct: 120 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVK 179 Query: 183 IVDKD 187 I + + Sbjct: 180 ITEDE 184 >3UNH-H nrPDB Length = 234 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 5/158 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ +D VIL + T V S +K ++P AG A DT + Sbjct: 3 IAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASK 62 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++L+++ E V+ +RQ L R + ++++GG D N P+LY++ G Sbjct: 63 MELHALSTGREPRVATVTRILRQTL---FRYQGHVGASLVVGGVDL--NGPQLYEVHPHG 117 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 + LP+ A G +LL+ ++P+MT E +LL Sbjct: 118 SYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELL 155 >5L4G-8 nrPDB Length = 277 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 5/158 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I +N Sbjct: 46 IAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSN 105 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++L+S+ + ++Q L R + +++GG D P LY I G Sbjct: 106 LELHSLSTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYPHG 160 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 + +LPY G ++ + +RPDM EE +L+ Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLV 198 >6HUB-H nrPDB Length = 234 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 5/158 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I +N Sbjct: 3 IAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSN 62 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++L+S+ + ++Q L R + +++GG D P LY I G Sbjct: 63 LELHSLSTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYPHG 117 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 + +LPY G ++ + +RPDM EE +L+ Sbjct: 118 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLV 155 >6AVO-C nrPDB Length = 204 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/191 (23%), Positives = 85/191 (44%), Gaps = 8/191 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L + Q VI A + G + +K +++P+ L + +G A D + + Sbjct: 4 LAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKEC 63 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 +LY +R +S A S + + + + +I G+DKK P LY +D GT Sbjct: 64 RLYYLRNGERISVSAASKLLSNMMCQ--YRGMGLSMGSMICGWDKKG--PGLYYVDEHGT 119 Query: 125 KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKI- 183 ++ + G Y + ++D YRP+++ EE DL + + R + G +V + Sbjct: 120 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHR--DSYSGGVVNMY 177 Query: 184 -VDKDGIRQVD 193 + +DG +V+ Sbjct: 178 HMKEDGWVKVE 188 >6EPF-2 nrPDB Length = 277 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 5/158 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I +N Sbjct: 46 IAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSN 105 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++L+S+ + ++Q L R + +++GG D P LY I G Sbjct: 106 LELHSLTTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYPHG 160 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 + +LPY G ++ + +RPDM EE L+ Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLV 198 >3UNF-K nrPDB Length = 204 Score = 57.8 bits (138), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 8/191 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L + Q VI+A T G + +K +++P+ L + +G A D + + Sbjct: 4 LAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLAKEC 63 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 +LY +R +S A S + + + + +I G+DKK P LY +D GT Sbjct: 64 RLYYLRNGERISVSAASKLLSNMMLQ--YRGMGLSMGSMICGWDKKG--PGLYYVDDNGT 119 Query: 125 KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKI- 183 ++ + G Y + ++D YR D++ EE DL + + R ++ G +V + Sbjct: 120 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHR--DNYSGGVVNMY 177 Query: 184 -VDKDGIRQVD 193 + +DG +V+ Sbjct: 178 HMKEDGWVKVE 188 >3NZW-K nrPDB Length = 287 Score = 57.4 bits (137), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L R Q +I+A T G V + K +++P L + AG A D + ++ + Sbjct: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQC 138 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQ-------VNVLIGGYDKKKNKPELY 117 +L+ +RE +S A A I S YQ + +I GY +K+ P +Y Sbjct: 139 RLHELREKERISVAA---------ASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIY 188 Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 +D GT+++ G + + +LD +Y+ D++ E+ L L K + R Sbjct: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 Query: 178 GVIVKIVDKDG 188 V + V +DG Sbjct: 249 SVNLYHVTEDG 259 >3H4P-A nrPDB Length = 264 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 7/159 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI +D V+LA + +T + ++ S +K Q+ H + +G D + + Sbjct: 42 IGIACKDGVVLAVDRRITSKLVKIR-SIEKIFQIDDHVAAATSGLVADARVLIDRARLEA 100 Query: 65 QLYSIREDYELSPQAVS---SFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 Q+Y + E+S + ++ ++Q + RP+ V++LI G DK N+ L++ D Sbjct: 101 QIYRLTYGEEISIEMLAKKICDIKQAYTQH-GGVRPFGVSLLIAGIDK--NEARLFETDP 157 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 G +E A G LL+ YR D+T +EGL+L Sbjct: 158 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 196 >5FGI-H nrPDB Length = 244 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I +N Sbjct: 15 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSN 74 Query: 64 IQLYSIREDYELSPQAVSSF--VRQELAKSIRSRRPYQVNV----LIGGYDKKKNKPELY 117 I+L+S+ E P+ VS+ ++Q L K YQ ++ ++ G D + L+ Sbjct: 75 IELHSLYTSRE--PRVVSALQMLKQHLFK-------YQGHIGAYLIVAGVDPTGS--HLF 123 Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQ 166 I G+ Y + G ++L+ H++ D+T EE + L +Q Sbjct: 124 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 172 >5CZ8-K nrPDB Length = 221 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 17/191 (8%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L R Q +I+A T G V + +++P L + AG A D + ++ + Sbjct: 13 LAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWETWLGSQC 72 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQ-------VNVLIGGYDKKKNKPELY 117 +L+ +RE +S A A I S YQ + +I GY +K+ P +Y Sbjct: 73 RLHELREKERISVAA---------ASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIY 122 Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 +D GT+++ G + + +LD +Y+ D++ E+ L L K + R Sbjct: 123 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 182 Query: 178 GVIVKIVDKDG 188 V + V +DG Sbjct: 183 SVNLYHVTEDG 193 >6AVO-B nrPDB Length = 234 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 5/158 (3%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ QD VIL + T V S +K ++P AG A D + + Sbjct: 3 IAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASK 62 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++L+++ E V+ +RQ L R + ++++GG D P+LY + G Sbjct: 63 MELHALSTGREPRVATVTRILRQTL---FRYQGHVGASLIVGGVD--LTGPQLYGVHPHG 117 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLL 161 + LP+ A G ++L+ ++P+MT E LL Sbjct: 118 SYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLL 155 >5L5A-K nrPDB Length = 211 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 79/184 (42%), Gaps = 4/184 (2%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L + Q VI A + G + +K +++P+ L + +G A D + + Sbjct: 4 LAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLAKEC 63 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 +LY +R +S A S + + + + +I G+DKK P LY +D GT Sbjct: 64 RLYYLRNGERISVSAASKLLSNMMCQ--YRGMGLSMGSMICGWDKKG--PGLYYVDEHGT 119 Query: 125 KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIV 184 ++ + G Y + +LD +Y+ D++ E+ L L K + R V + V Sbjct: 120 RLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 179 Query: 185 DKDG 188 +DG Sbjct: 180 TEDG 183 >5FMG-E nrPDB Length = 256 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 19/181 (10%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI V D VILAS + ++ + + KDS +K + H + +G D +Y + Sbjct: 38 VGICVNDGVILASERRISSTL-IEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVEC 96 Query: 65 QLY--------SIREDYELSPQAVSSFVRQELAKSIRSR---RPYQVNVLIGGYDKKKNK 113 Y +I+ EL + F L+ S R + RP+ V +LIGG DK N Sbjct: 97 NHYKFIYNENINIKSCVELISELALDF--SNLSDSKRKKIMSRPFGVALLIGGVDK--NG 152 Query: 114 PELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCV--QELEKR 171 P L+ + GT + G + LL +Y+ DMT E+ ++L L V Q +E + Sbjct: 153 PCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQA-EILALTVLRQVMEDK 211 Query: 172 M 172 + Sbjct: 212 L 212 >5FMG-L nrPDB Length = 211 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 35/160 (21%), Positives = 80/160 (50%), Gaps = 8/160 (5%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L + +D +I+A + G + + +K +++ + L + AG A D + + +Y+ I Sbjct: 4 LAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLGKII 63 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQV--NVLIGGYDKKKNKPELYQIDYL 122 ++Y +R + ++S +A S+ L+ + + Y + +++ GYD ++ +D Sbjct: 64 KIYELRNNEKISVRAASTI----LSNILYQYKGYGLCCGIILSGYDH--TGFNMFYVDDS 117 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 G KVE + G Y +S+LD Y ++ ++ ++L + Sbjct: 118 GKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELAR 157 >4Y8P-I nrPDB Length = 205 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 3/148 (2%) Query: 41 HTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQV 100 H + G A D E + LY ++E+ + P+ + V L + R PY V Sbjct: 48 HVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYE--RRFGPYFV 105 Query: 101 NVLIGGYDKKKNKPELYQIDYLGTKVELP-YGAHGYSGFYTFSLLDHHYRPDMTTEEGLD 159 ++ G + K KP + D +G E + G + F + + Y P++ E+ + Sbjct: 106 GPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFE 165 Query: 160 LLKLCVQELEKRMPMDFKGVIVKIVDKD 187 + + R + G +V I+ KD Sbjct: 166 TISQALLNAADRDALSGWGAVVYIIKKD 193 >6HV7-H nrPDB Length = 226 Score = 49.7 bits (117), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I G+ QD VIL + T V S +K ++P AG A D + I +N Sbjct: 3 IAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIGSN 62 Query: 64 IQLYSIREDYELSPQAVSSF--VRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 I+L+S+ E P+ VS+ ++Q L K Y +++ G D + L+ I Sbjct: 63 IELHSLYTSRE--PRVVSALQMLKQHLFKYQGHIGAY---LIVAGVDPTGS--HLFSIHA 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQ 166 G+ Y + G ++L+ H++ D+T EE + L +Q Sbjct: 116 HGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ 160 >5FMG-C nrPDB Length = 246 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 I +G+ +D VIL + K + ++ +K ++ H AG D A + Sbjct: 33 ITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNAD----ANILIN 88 Query: 63 NIQLYSIREDYELSP-QAVSSFVRQ--ELAKSIRSR---RPYQVNVLIGGYDKKKNKPEL 116 +LY+ R Y + Q VS V Q ++ +S RPY V+ LIGGYD K+ +L Sbjct: 89 QSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYD-TKDGYQL 147 Query: 117 YQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEG 157 Y D G A G + S+L ++ DMT EEG Sbjct: 148 YHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEG 188 >4YA5-C nrPDB Length = 254 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 40/188 (21%), Positives = 86/188 (45%), Gaps = 8/188 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +G++ ++ V+L + T + + + K ++ H ++SF+G D+ E + Sbjct: 34 VGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILIEKARVEA 93 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQIDYL 122 Q + + + ++ + ++ +V + +S RP+ V+ LI G+D + ++P+LYQ + Sbjct: 94 QSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPS 153 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHY---RPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 G G + L+ +Y P T EE +KL V+ L + + K + Sbjct: 154 GIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEE---CVKLTVRSLLEVVQTGAKNI 210 Query: 180 IVKIVDKD 187 + +V D Sbjct: 211 EITVVKPD 218 >3UNE-I nrPDB Length = 205 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 3/187 (1%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 ++ ++ ++ V +A+ + ++ K + + AG A D A+ ++ Sbjct: 11 VMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFR 70 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 + LY ++E ++ P + S V L + + PY +I G D K KP + +D +G Sbjct: 71 LNLYELKEGRQIKPYTLMSMVANLLYE--KRFGPYYTEPVIAGLDPKTFKPFICSLDLIG 128 Query: 124 TK-VELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 V + G + + + + P+M E + + + R + GVIV Sbjct: 129 CPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVH 188 Query: 183 IVDKDGI 189 +++KD I Sbjct: 189 VIEKDKI 195 >6EPC-1 nrPDB Length = 238 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/193 (22%), Positives = 76/193 (39%), Gaps = 11/193 (5%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I+ ++ V+L + T G + DK + H +G A DT A+ + Sbjct: 36 IMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAVTYQ 95 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 + +SI + +S ++ R R ++I G+D ++ ++Y + G Sbjct: 96 LGFHSIELNEPPLVHTAASLFKE---MCYRYREDLMAGIIIAGWDPQEGG-QVYSVPMGG 151 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK--GVI- 180 V + G Y + +D YR MT +E L+ L M D GVI Sbjct: 152 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKDE---CLQFTANALALAMERDGSSGGVIR 208 Query: 181 VKIVDKDGI-RQV 192 + + + G+ RQV Sbjct: 209 LAAIQQSGVERQV 221 >5FMG-N nrPDB Length = 265 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 52/223 (23%), Positives = 93/223 (41%), Gaps = 42/223 (18%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI-QA 62 ++ I+ + +++A+ + + G + ++ +++ T+M F+GE D E + + Sbjct: 12 VIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLHELLTRK 71 Query: 63 NIQLYSIREDYE--LSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGG------------ 106 NI S ++ E +PQ S+V + +R R P N++I G Sbjct: 72 NINNLSEKKRKEDMYTPQHYHSYVSRVFY--VRKNRIDPLFNNIIIAGINSQKYDNNDDN 129 Query: 107 ---YDKKKN-----------------KPELYQ--IDYLGTKVELPYGAHGYSGFYTFSLL 144 Y K N K +LY +D GT Y GY+ ++ +LL Sbjct: 130 VLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFALTLL 189 Query: 145 DHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV-IVKIVDK 186 HY+ +MT EE L+ C++ L R + IVK+ K Sbjct: 190 RDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSK 232 >5LF6-M nrPDB Length = 219 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 90/197 (45%), Gaps = 21/197 (10%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 +LG++ + V++A+ + G + + +++ T++ G +GD F +Y++ Sbjct: 11 VLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTML---GASGDYADF-QYLKQV 66 Query: 64 IQLYSIRED-----YELSPQAVSSFVRQELAKSIRSRR----PYQVNVLIGGYDKKKNKP 114 + I E+ + SP+A+ S+ L +++ SRR P ++IGGY + Sbjct: 67 LGQMVIDEELLGDGHSYSPRAIHSW----LTRAMYSRRSKMNPLWNTMVIGGY--ADGES 120 Query: 115 ELYQIDYLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCVQELEKRM 172 L +D LG E P A GY + LL +P ++ E DL++ C++ L R Sbjct: 121 FLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRD 180 Query: 173 PMDFKGVIVKIVDKDGI 189 + + V + G+ Sbjct: 181 ARSYNRFQIATVTEKGV 197 >5GJQ-g nrPDB Length = 264 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 91/197 (46%), Gaps = 21/197 (10%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 +LG++ + V++A+ + G + + +++ T++ G +GD F +Y++ Sbjct: 56 VLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTML---GASGDYADF-QYLKQV 111 Query: 64 IQLYSIRED-----YELSPQAVSSFVRQELAKSIRSRR----PYQVNVLIGGYDKKKNKP 114 + I E+ + SP+A+ S+ L +++ SRR P ++IGGY ++ Sbjct: 112 LGQMVIDEELLGDGHSYSPRAIHSW----LTRAMYSRRSKMNPLWNTMVIGGYADGESF- 166 Query: 115 ELYQIDYLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCVQELEKRM 172 L +D LG E P A GY + LL +P ++ E DL++ C++ L R Sbjct: 167 -LGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRD 225 Query: 173 PMDFKGVIVKIVDKDGI 189 + + V + G+ Sbjct: 226 ARSYNRFQIATVTEKGV 242 >5LEZ-N nrPDB Length = 205 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 4/157 (2%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I+ ++ V+L + T G + DK + +G A DT A+ + Sbjct: 3 IMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQ 62 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 + +SI + +S ++ R R ++I G+D ++ ++Y + G Sbjct: 63 LGFHSIELNEPPLVHTAASLFKE---MCYRYREDLMAGIIIAGWDPQEGG-QVYSVPMGG 118 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 V + G Y + +D YR MT EE L Sbjct: 119 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQF 155 >5GJQ-a nrPDB Length = 239 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 4/157 (2%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 I+ ++ V+L + T G + DK + +G A DT A+ + Sbjct: 37 IMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQ 96 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 + +SI + +S ++ R R ++I G+D ++ ++Y + G Sbjct: 97 LGFHSIELNEPPLVHTAASLFKE---MCYRYREDLMAGIIIAGWDPQEGG-QVYSVPMGG 152 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 V + G Y + +D YR MT EE L Sbjct: 153 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQF 189 >6EPE-7 nrPDB Length = 263 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 35/213 (16%) Query: 4 ILGIRVQDSVILAS-------SKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQF 56 +LG++ V++A+ S A R IS + +D T G +GD F Sbjct: 55 VLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDST----------MLGASGDYADF 104 Query: 57 AEYIQANIQLYSIRED-----YELSPQAVSSFVRQELAKSIRSRR----PYQVNVLIGGY 107 +Y++ + I E+ + SP+A+ S+ L +++ SRR P +IGGY Sbjct: 105 -QYLKQVLGQMVIDEELFGDGHSYSPRAIHSW----LTRAMYSRRSKMNPLWNTKVIGGY 159 Query: 108 DKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCV 165 ++ L +D LG E P A GY + LL +P ++ E +L++ C+ Sbjct: 160 AGGESF--LGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCM 217 Query: 166 QELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ 198 + L R + V V + G+ AQ Sbjct: 218 RVLYYRDARSYNRFQVATVTEKGVEIEGPLSAQ 250 >5GJR-F nrPDB Length = 241 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 10/161 (6%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI+ + V LA K +T + + S +K ++ H + +G D + + Sbjct: 38 IGIQTSEGVCLAVEKRITSPL-MEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVET 96 Query: 65 Q----LYSIREDYELSPQAVSSFVRQ---ELAKSIRSRRPYQVNVLIGGYDKKKNKPELY 117 Q Y+ E QAVS+ Q E A RP+ V +L GG D+K P+L+ Sbjct: 97 QNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEK--GPQLF 154 Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGL 158 +D GT V+ A G + S L Y MT +E + Sbjct: 155 HMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAI 195 >5LEZ-C nrPDB Length = 248 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/190 (23%), Positives = 84/190 (44%), Gaps = 15/190 (7%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQ----LSPHTLMSFAGEAGDTVQFAEYI 60 +G+R +D V+L K SV K D++T + L + M+FAG D Sbjct: 33 VGVRGRDIVVLGVEKK-----SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRA 87 Query: 61 QANIQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELY 117 + Q + + + ++ + ++ ++ +Q +S RRP+ ++ LI G+D P LY Sbjct: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS-NGRRPFGISALIVGFD-FDGTPRLY 145 Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 Q D GT A G L+ +Y + + L +KL ++ L + + K Sbjct: 146 QTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDL-TIKLVIKALLEVVQSGGK 204 Query: 178 GVIVKIVDKD 187 + + ++ +D Sbjct: 205 NIELAVMRRD 214 >6HE5-A nrPDB Length = 247 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 73/167 (43%), Gaps = 24/167 (14%) Query: 5 LGIRVQDSVILASSKAVTRGISVLK-DSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 +GI+ ++ VIL + K V G +L+ D+ +K ++ H + +G D + + Sbjct: 39 IGIKCKEGVILIADKRV--GSKLLEADTIEKIYKIDEHICAATSGLVADARVLIDRARIE 96 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSI----------RSRRPYQVNVLIGGYDKKKNK 113 Q+ + D P V +ELAK I RP+ V++LI G D+ Sbjct: 97 AQINRLTYD---EPITV-----KELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV--- 145 Query: 114 PELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 P+LY+ D G +E A G + YR D++ ++ + L Sbjct: 146 PKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVL 192 >5FMG-M nrPDB Length = 240 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 ++G+ +D VILA+ ++ S+ K +L+ ++ +G D +Q Sbjct: 40 VIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSLLQKK 99 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGGYDKKKNKPELYQIDY 121 IQL+ + + ++ L + SRR PY ++ G D + NK LY D Sbjct: 100 IQLFVLEHSHYPDIHVIARL----LCVILYSRRFFPYYAFNILAGVD-ENNKGVLYNYDS 154 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDH 146 +G+ E + G +LD+ Sbjct: 155 VGSYCEATHSCVGSGSQLILPILDN 179 >1G0U-D nrPDB Length = 241 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 5/191 (2%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI ++ V+L K T + + DS +K ++ H + +G D E+ + Sbjct: 38 IGIATKEGVVLGVEKRATSPL-LESDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAA 96 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGT 124 +++ D +++ ++++ V +LA + RP+ V +LI G+D + +L+ + GT Sbjct: 97 VTHNLYYDEDINVESLTQSV-CDLAAAAAMSRPFGVALLIAGHD-ADDGYQLFHAEPSGT 154 Query: 125 KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEG-LDLLKLCVQELEKRMPMDFKGVIVKI 183 A G + L + + +T +E L +LK+ Q +E+++ + + I Sbjct: 155 FYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDEN-NAQLSCI 213 Query: 184 VDKDGIRQVDD 194 +DG + D+ Sbjct: 214 TKQDGFKIYDN 224 >4FZC-A nrPDB Length = 250 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 38/167 (22%), Positives = 76/167 (45%), Gaps = 7/167 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ--A 62 LGI+ + V++A+ K + ++ + ++ K L+P ++G D + + A Sbjct: 35 LGIKATNGVVIATEKKSSSPLA-MSETLSKVSLLTPDIGAVYSGMGPDYRVLVDKSRKVA 93 Query: 63 NIQLYSIREDYELSPQAVSSFVR--QELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 + I +Y + VS + QE +S RP+ V++LI G+D + N LYQ+D Sbjct: 94 HTSYKRIYGEYPPTKLLVSEVAKIMQEATQS-GGVRPFGVSLLIAGHD-EFNGFSLYQVD 151 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQE 167 G+ A G + L+ + ++ E+ + + L ++E Sbjct: 152 PSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKE 198 >5FMG-J nrPDB Length = 218 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 38/171 (22%), Positives = 73/171 (42%), Gaps = 20/171 (11%) Query: 3 IILGIRVQDSVILASS-KAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +LG+ + V +A + + + K +++ + + +G A D E ++ Sbjct: 11 CVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYEILR 70 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGGY----------DK 109 + LY +R+D E+ + ++ L+ + S R PY VN ++ G+ +K Sbjct: 71 YRVNLYEVRQDAEMDVECFANM----LSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEK 126 Query: 110 KKN-KPELYQIDYLGTKVEL-PYGAHGYSGFYTFSLLDHHYRPDMTTEEGL 158 K N +P L D +G K E + +G + F + + Y D E GL Sbjct: 127 KVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQ-DENGL 176 >3NZW-E nrPDB Length = 234 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 + +G+R +L A+ R L K + H +S AG A D + Y++ Sbjct: 34 VTVGLRSNTHAVLV---ALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQ 90 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRS--RRPYQVNVLIGGYDK 109 S+ + +L+ + + + K+ +S RPY V +LI GYDK Sbjct: 91 QCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDK 139 >3NZW-L nrPDB Length = 241 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 48/206 (23%), Positives = 81/206 (39%), Gaps = 21/206 (10%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 ILGI +D +LA S+ + K + +MS G A D + + + Sbjct: 31 ILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNS 90 Query: 64 IQLYSI-REDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 ++ Y D +LS + + ++ L + PY V+ +I G D + K +Y D + Sbjct: 91 VKWYHFDHNDKKLSINSAARNIQHLLYG--KRFFPYYVHTIIAGLD-EDGKGAVYSFDPV 147 Query: 123 GTKVELPYGAHGYSGFYTFSLLD------HHYRPDMTTEEGLDLLKLCVQELEKRMPMDF 176 G+ A G + LD + Y P + L L V+E+ K + F Sbjct: 148 GSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSF 207 Query: 177 K-----------GVIVKIVDKDGIRQ 191 G+ + IV KDG+R+ Sbjct: 208 TSATERHIQVGDGLEILIVTKDGVRK 233 >1T6M-A nrPDB Length = 299 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 24/43 (55%) Query: 76 SPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 SP +S++ E+A I+ + P +V +I Y +K P LYQ Sbjct: 245 SPYYYASYINPEIANDIKQKNPTRVGWVIQDYINEKWSPLLYQ 287 >5T0I-L nrPDB Length = 268 Score = 30.4 bits (67), Expect = 0.53, Method: Compositional matrix adjust. Identities = 44/193 (22%), Positives = 76/193 (39%), Gaps = 20/193 (10%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +G++ + +L A+ R S L K + H +S AG D +++ Sbjct: 41 VGLKSKTHAVLV---ALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQEC 97 Query: 65 QLYSIREDYELSPQAVSSFV--RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI--- 119 D L + S + + ++ RRPY V +LI GYD P ++Q Sbjct: 98 LDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDM--GPHIFQTCPS 155 Query: 120 -DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMP----M 174 +Y + + GA S + L+ H M +L+K ++ L + +P + Sbjct: 156 ANYFDCRA-MSIGARSQSA---RTYLERHMSEFMECNLN-ELVKHGLRALRETLPAEQDL 210 Query: 175 DFKGVIVKIVDKD 187 K V + IV KD Sbjct: 211 TTKNVSIGIVGKD 223 >5LIE-A nrPDB Length = 414 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 10/72 (13%) Query: 41 HTLMSFAGE------AGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRS 94 H L S E AG + AE QL ++R D+EL P A+ VR + S Sbjct: 248 HLLFSAGAETTRNSIAGGLLALAENPD---QLQTLRSDFELLPTAIEEIVRWT-SPSPSK 303 Query: 95 RRPYQVNVLIGG 106 RR V +GG Sbjct: 304 RRTASRAVSLGG 315 >3SI9-A nrPDB Length = 315 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 19/25 (76%) Query: 150 PDMTTEEGLDLLKLCVQELEKRMPM 174 P +T EE +++LCV+++ KR+P+ Sbjct: 70 PTLTHEEHKRIIELCVEQVAKRVPV 94 >1R1N-A nrPDB Length = 309 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 13/67 (19%) Query: 24 GISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSF 83 G +VLK S +K EA V F + L ++R +Y L+P VS+F Sbjct: 229 GAAVLKSSQNKD-------------EAKKFVAFLAGKEGQRALTAVRAEYPLNPHVVSTF 275 Query: 84 VRQELAK 90 + +AK Sbjct: 276 NLEPIAK 282 >6J30-C nrPDB Length = 258 Score = 27.7 bits (60), Expect = 3.1, Method: Compositional matrix adjust. Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 9/161 (5%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDT---VQFAEYIQ 61 +GI D ++LA+ + VT + S +K +L+ ++ AG D + A I Sbjct: 36 IGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTAR-IH 94 Query: 62 ANIQLYSIRED--YELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 A L + ED E+ + +S ++Q + RP+ V+ + GYD + +LY Sbjct: 95 AQNYLKTYNEDIPVEILVRRLSD-IKQGYTQH-GGLRPFGVSFIYAGYDDRYGY-QLYTS 151 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 + G + G + +LL Y+ DM ++ ++L Sbjct: 152 NPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIEL 192 >2AF0-A nrPDB Length = 146 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 57 AEYIQANIQLYSIREDYEL--SPQAVSSFVRQELAKSIRSRRPYQVNV 102 +E+ + NI+ + ED++ SPQ +SS R+ I P ++N+ Sbjct: 46 SEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINI 93 >6FVW-g nrPDB Length = 245 Score = 27.7 bits (60), Expect = 3.8, Method: Compositional matrix adjust. Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 33/161 (20%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI+ D V+ A K +T + ++ + K + + H ++G D + Sbjct: 35 IGIKCNDGVVFAVEKLITSKL-LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVN--RGRE 91 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR------RPYQVNVLIGGYDKKKNKPELYQ 118 + S ++ Y+ +P + +F + L + +++ RP+ V+ + GG D KN LY Sbjct: 92 EAASFKKLYK-TPIPIPAFADR-LGQYVQAHTLYNSVRPFGVSTIFGGVD--KNGAHLYM 147 Query: 119 IDYLGTKVELPYGAH-GYSGFYTF-----------SLLDHH 147 ++ P G++ GY G T L+DHH Sbjct: 148 LE--------PSGSYWGYKGAATGKGRQSAKAELEKLVDHH 180 >4NZ0-A nrPDB Length = 460 Score = 27.3 bits (59), Expect = 4.0, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 23/49 (46%) Query: 149 RPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQA 197 R D+ E L+ + LEK DF ++ + KD +R ++ QA Sbjct: 122 RTDVVDWETATLIPFAAERLEKMNNKDFSDIVYQTFLKDELRPIEKVQA 170 >5GM6-a nrPDB Length = 259 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 8/70 (11%) Query: 43 LMSFAGEAGD-TVQFAEYIQANIQL-------YSIREDYELSPQAVSSFVRQELAKSIRS 94 LMS A T+Q + + +Q Y++ + + + + + +F R+ELA+ + Sbjct: 42 LMSLAKSGNSRTLQLSHENEGKLQKKGEDLDKYTLTVNDDSTKEDLLNFERKELAEKAKK 101 Query: 95 RRPYQVNVLI 104 RRP N L+ Sbjct: 102 RRPSDDNELV 111 >4ECK-A nrPDB Length = 610 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 2/34 (5%) Query: 165 VQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ 198 ++E +R P F IV I++K+ I+++DDF A+ Sbjct: 560 LKEQLRREPRPFP--IVNILNKERIKEIDDFTAE 591 >5T0L-A nrPDB Length = 566 Score = 27.3 bits (59), Expect = 4.6, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 2/34 (5%) Query: 165 VQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ 198 ++E +R P F IV I++K+ I+++DDF A+ Sbjct: 516 LKEQLRREPRPFP--IVNILNKERIKEIDDFTAE 547 >5FGG-F nrPDB Length = 288 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 33/161 (20%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI+ D V+ A K +T + ++ + K + + H ++G D + Sbjct: 38 IGIKCNDGVVFAVEKLITSKL-LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVN--RGRE 94 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR------RPYQVNVLIGGYDKKKNKPELYQ 118 + S ++ Y+ +P + +F + L + +++ RP+ V+ + GG D KN LY Sbjct: 95 EAASFKKLYK-TPIPIPAFADR-LGQYVQAHTLYNSVRPFGVSTIFGGVD--KNGAHLYM 150 Query: 119 IDYLGTKVELPYGAH-GYSGFYTF-----------SLLDHH 147 ++ P G++ GY G T L+DHH Sbjct: 151 LE--------PSGSYWGYKGAATGKGRQSAKAELEKLVDHH 183 >1D5A-A nrPDB Length = 733 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 20/117 (17%) Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 ++ + +R+ YE + A + +ELA+ S GGY K+ K I YL Sbjct: 353 VEWFLLRKAYERNDVAPNKPDERELARRTES--------YAGGYVKEPEKGLWENIVYLD 404 Query: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Y Y ++ H+ PD EG + Q + R DF G I Sbjct: 405 -----------YKSLYPSIIITHNVSPDTLNREGCREYDVAPQ-VGHRFCKDFPGFI 449 >4PV4-A nrPDB Length = 445 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 10/29 (34%), Positives = 19/29 (65%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDD 33 +GIR++D +++ ++ SV+KD DD Sbjct: 400 IGIRIEDDIVITATGNENLTASVVKDPDD 428 >3K30-A nrPDB Length = 690 Score = 26.6 bits (57), Expect = 8.0, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 14/22 (63%) Query: 130 YGAHGYSGFYTFSLLDHHYRPD 151 YGAHGYSG + F ++ R D Sbjct: 176 YGAHGYSGVHHFLSKRYNQRTD 197 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FGE-J nrPDB 235 1e-62 3WXR-K nrPDB 232 5e-62 5L5A-K nrPDB 207 2e-54 6AVO-C nrPDB 204 2e-53 3NZW-K nrPDB 201 1e-52 5CZ8-K nrPDB 195 1e-50 3UNF-K nrPDB 194 2e-50 6AVO-B nrPDB 194 2e-50 3H4P-a nrPDB 192 6e-50 6EPF-2 nrPDB 192 8e-50 3UNH-H nrPDB 192 1e-49 5L4G-8 nrPDB 190 2e-49 6HUB-H nrPDB 189 5e-49 5LF3-J nrPDB 189 5e-49 6EPC-1 nrPDB 189 7e-49 5GJQ-a nrPDB 187 2e-48 5FMG-I nrPDB 186 5e-48 5LEZ-N nrPDB 185 1e-47 5FGI-H nrPDB 184 1e-47 6HV7-H nrPDB 184 2e-47 3UNE-I nrPDB 183 5e-47 3IPM-H nrPDB 177 4e-45 6HEC-1 nrPDB 176 5e-45 5FMG-L nrPDB 172 8e-44 6EPE-7 nrPDB 169 8e-43 5FMG-K nrPDB 166 5e-42 4Y8P-I nrPDB 166 6e-42 5MPC-h nrPDB 165 8e-42 4YA5-C nrPDB 165 1e-41 5GJQ-g nrPDB 163 5e-41 5LF6-M nrPDB 160 2e-40 5FMG-N nrPDB 160 3e-40 3H4P-A nrPDB 155 8e-39 5FMG-E nrPDB 155 9e-39 5LEZ-C nrPDB 150 3e-37 5GJR-F nrPDB 149 1e-36 6HE5-A nrPDB 144 3e-35 5FMG-C nrPDB 141 2e-34 Sequences not found previously or not previously below threshold: 5L64-K nrPDB 195 1e-50 6EPF-5 nrPDB 188 1e-48 5LN3-5 nrPDB 185 1e-47 3UNB-K nrPDB 180 2e-46 6AVO-A nrPDB 151 2e-37 3UNF-N nrPDB 140 3e-34 1G0U-D nrPDB 137 3e-33 2Z5C-C nrPDB 132 8e-32 5FMG-D nrPDB 126 6e-30 6J30-C nrPDB 125 1e-29 5L4G-U nrPDB 119 8e-28 5VFT-S nrPDB 118 1e-27 2KU2-A nrPDB 117 3e-27 6EPF-6 nrPDB 116 5e-27 5FMG-J nrPDB 116 8e-27 5LE5-B nrPDB 115 1e-26 5LF0-A nrPDB 114 2e-26 5FMG-B nrPDB 112 1e-25 5FMG-M nrPDB 112 1e-25 4FZC-A nrPDB 112 2e-25 6GOP-M nrPDB 105 1e-23 3NZW-L nrPDB 105 1e-23 5FMG-H nrPDB 103 6e-23 6FVW-g nrPDB 100 3e-22 5FGG-F nrPDB 100 4e-22 5T0I-L nrPDB 92 2e-19 5FMG-F nrPDB 88 3e-18 1Q5Q-H nrPDB 88 3e-18 1IRU-A nrPDB 88 3e-18 6EPD-G nrPDB 87 4e-18 1Q5R-H nrPDB 87 6e-18 3NZW-E nrPDB 84 4e-17 2JAY-A nrPDB 82 2e-16 5LZP-A nrPDB 79 1e-15 5FMG-G nrPDB 69 1e-12 5FMG-A nrPDB 65 3e-11 5L5W-G nrPDB 63 1e-10 5LOY-A nrPDB 60 5e-10 5JI2-A nrPDB 53 1e-07 4HO7-A nrPDB 51 4e-07 1OFH-G nrPDB 47 6e-06 5LOX-A nrPDB 47 8e-06 5NYF-A nrPDB 45 1e-05 1M4Y-A nrPDB 42 3e-04 2Z3B-A nrPDB 36 0.012 3TY6-A nrPDB 35 0.024 1RFZ-A nrPDB 32 0.13 1WFZ-A nrPDB 29 1.1 5KZ5-a nrPDB 29 1.1 5WKP-D nrPDB 29 1.2 3MUN-A nrPDB 29 1.8 4ZYS-A nrPDB 28 2.7 3ML0-B nrPDB 28 2.7 6FEC-5 nrPDB 28 3.4 3J8B-H nrPDB 27 4.0 6D97-A nrPDB 27 4.5 >5FGE-J nrPDB Length = 198 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI Sbjct: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID Sbjct: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 181 VKIVDKDGIRQVDDFQAQ 198 VKIVDKDGIRQVDDFQAQ Sbjct: 181 VKIVDKDGIRQVDDFQAQ 198 >3WXR-K nrPDB Length = 238 Score = 232 bits (593), Expect = 5e-62, Method: Composition-based stats. Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI Sbjct: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID Sbjct: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 181 VKIVDKDGIRQVDDFQAQ 198 VKIVDKDGIRQVDDFQAQ Sbjct: 181 VKIVDKDGIRQVDDFQAQ 198 >5L5A-K nrPDB Length = 211 Score = 207 bits (528), Expect = 2e-54, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 4/188 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + Q VI A + G + +K +++P+ L + +G A D + + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +LY +R +S A S + + + + +I G+DKK P LY +D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQ--YRGMGLSMGSMICGWDKK--GPGLYYVDE 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT++ + G Y + +LD +Y+ D++ E+ L L K + R V + Sbjct: 117 HGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 Query: 182 KIVDKDGI 189 V +DG Sbjct: 177 YHVTEDGW 184 >6AVO-C nrPDB Length = 204 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 4/192 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + Q VI A + G + +K +++P+ L + +G A D + + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +LY +R +S A S + + + + +I G+DKK P LY +D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQ--YRGMGLSMGSMICGWDKK--GPGLYYVDE 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT++ + G Y + ++D YRP+++ EE DL + + R V + Sbjct: 117 HGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNM 176 Query: 182 KIVDKDGIRQVD 193 + +DG +V+ Sbjct: 177 YHMKEDGWVKVE 188 >3NZW-K nrPDB Length = 287 Score = 201 bits (512), Expect = 1e-52, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 3/188 (1%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L R Q +I+A T G V + K +++P L + AG A D + ++ Sbjct: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + +L+ +RE +S A S + + + + +I GY +K+ P +Y +D Sbjct: 136 SQCRLHELREKERISVAAASKILSNLVYQ--YKGAGLSMGTMICGYTRKE-GPTIYYVDS 192 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT+++ G + + +LD +Y+ D++ E+ L L K + R V + Sbjct: 193 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 Query: 182 KIVDKDGI 189 V +DG Sbjct: 253 YHVTEDGW 260 >5CZ8-K nrPDB Length = 221 Score = 195 bits (495), Expect = 1e-50, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 81/188 (43%), Gaps = 3/188 (1%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L R Q +I+A T G V + +++P L + AG A D + ++ Sbjct: 10 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWETWLG 69 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + +L+ +RE +S A S + + + + +I GY +K+ P +Y +D Sbjct: 70 SQCRLHELREKERISVAAASKILSNLVYQ--YKGAGLSMGTMICGYTRKE-GPTIYYVDS 126 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT+++ G + + +LD +Y+ D++ E+ L L K + R V + Sbjct: 127 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 186 Query: 182 KIVDKDGI 189 V +DG Sbjct: 187 YHVTEDGW 194 >5L64-K nrPDB Length = 211 Score = 195 bits (495), Expect = 1e-50, Method: Composition-based stats. Identities = 42/188 (22%), Positives = 80/188 (42%), Gaps = 4/188 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + + VI+A+ T G + + K +++P+ L + AG A D + + Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++Y +R +S A S + + + + +I G+DK+ P LY +D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQ--YKGMGLSMGTMICGWDKR--GPGLYYVDS 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G ++ + G Y + +LD +Y+ D++ E+ L L K + R V + Sbjct: 117 EGNRISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 Query: 182 KIVDKDGI 189 V +DG Sbjct: 177 YHVTEDGW 184 >3UNF-K nrPDB Length = 204 Score = 194 bits (493), Expect = 2e-50, Method: Composition-based stats. Identities = 45/192 (23%), Positives = 82/192 (42%), Gaps = 4/192 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + Q VI+A T G + +K +++P+ L + +G A D + + Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +LY +R +S A S + + + + +I G+DKK P LY +D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQ--YRGMGLSMGSMICGWDKK--GPGLYYVDD 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT++ + G Y + ++D YR D++ EE DL + + R V + Sbjct: 117 NGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNM 176 Query: 182 KIVDKDGIRQVD 193 + +DG +V+ Sbjct: 177 YHMKEDGWVKVE 188 >6AVO-B nrPDB Length = 234 Score = 194 bits (493), Expect = 2e-50, Method: Composition-based stats. Identities = 45/196 (22%), Positives = 79/196 (40%), Gaps = 5/196 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ QD VIL + T V S +K ++P AG A D + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + ++L+++ E V+ +RQ L R + ++++GG D P+LY + Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTL---FRYQGHVGASLIVGGVDL--TGPQLYGVHP 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ LP+ A G ++L+ ++P+MT E LL V V Sbjct: 116 HGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDA 175 Query: 182 KIVDKDGIRQVDDFQA 197 ++ K G + + + Sbjct: 176 CVITKTGAKLLRTLSS 191 >3H4P-a nrPDB Length = 219 Score = 192 bits (489), Expect = 6e-50, Method: Composition-based stats. Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 4/195 (2%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 M +G+ D+VILA+ K + G V K ++ + M+ AG GD + Sbjct: 1 MTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 A +LY +R + P A ++ + L S P+ ++IGGYD + +L+ +D Sbjct: 61 IAEAKLYKMRTGRNIPPLACATLLSNILHSS--RMFPFLTQIIIGGYDLLE-GAKLFSLD 117 Query: 121 YLGTKVELP-YGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 LG E + A G + +L+ Y DM+ EEG+ L ++ +R G+ Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 180 IVKIVDKDGIRQVDD 194 + ++ KDG++ +D Sbjct: 178 SLAVITKDGVKIFED 192 >6EPF-2 nrPDB Length = 277 Score = 192 bits (488), Expect = 8e-50, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 5/195 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I Sbjct: 44 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 103 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +N++L+S+ + ++Q L R + +++GG D P LY I Sbjct: 104 SNLELHSLTTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYP 158 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ +LPY G ++ + +RPDM EE L+ + + + Sbjct: 159 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDL 218 Query: 182 KIVDKDGIRQVDDFQ 196 ++ K + + + Sbjct: 219 CVISKSKLDFLRPYS 233 >3UNH-H nrPDB Length = 234 Score = 192 bits (487), Expect = 1e-49, Method: Composition-based stats. Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 5/195 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ +D VIL + T V S +K ++P AG A DT Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + ++L+++ E V+ +RQ L R + ++++GG D N P+LY++ Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTL---FRYQGHVGASLVVGGVDL--NGPQLYEVHP 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ LP+ A G +LL+ ++P+MT E +LL + V Sbjct: 116 HGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDA 175 Query: 182 KIVDKDGIRQVDDFQ 196 ++ G + Sbjct: 176 CVITAGGAKLQRALS 190 >5L4G-8 nrPDB Length = 277 Score = 190 bits (484), Expect = 2e-49, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 81/195 (41%), Gaps = 5/195 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I Sbjct: 44 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 103 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +N++L+S+ + ++Q L R + +++GG D P LY I Sbjct: 104 SNLELHSLSTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYP 158 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ +LPY G ++ + +RPDM EE +L+ + + + Sbjct: 159 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218 Query: 182 KIVDKDGIRQVDDFQ 196 ++ K+ + + + Sbjct: 219 CVISKNKLDFLRPYT 233 >6HUB-H nrPDB Length = 234 Score = 189 bits (481), Expect = 5e-49, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 81/195 (41%), Gaps = 5/195 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ +D ++L + T G+ V + K +SP+ AG A DT + I Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +N++L+S+ + ++Q L R + +++GG D P LY I Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQML---FRYQGYIGAALVLGGVD--VTGPHLYSIYP 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ +LPY G ++ + +RPDM EE +L+ + + + Sbjct: 116 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDL 175 Query: 182 KIVDKDGIRQVDDFQ 196 ++ K+ + + + Sbjct: 176 CVISKNKLDFLRPYT 190 >5LF3-J nrPDB Length = 201 Score = 189 bits (481), Expect = 5e-49, Method: Composition-based stats. Identities = 87/196 (44%), Positives = 128/196 (65%), Gaps = 1/196 (0%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 M+ ++GI+ D V++AS + I +KD DK ++S L+ GEAGDTVQFAEYI Sbjct: 1 MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Q N+QLY +R YELSP A ++F R+ LA +RSR PY VN+L+ GYD+ + P LY +D Sbjct: 61 QKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHE-GPALYYMD 119 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 YL + P+ AHGY F T S+LD +Y P ++ E ++LL+ C++EL+KR ++ Sbjct: 120 YLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFS 179 Query: 181 VKIVDKDGIRQVDDFQ 196 V+I+DK+GI +D+ Sbjct: 180 VRIIDKNGIHDLDNIS 195 >6EPC-1 nrPDB Length = 238 Score = 189 bits (480), Expect = 7e-49, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 70/189 (37%), Gaps = 4/189 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ ++ V+L + T G + DK + H +G A DT A+ + Sbjct: 34 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAVT 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + +SI + +S ++ R R ++I G+D ++ ++Y + Sbjct: 94 YQLGFHSIELNEPPLVHTAASLFKEM---CYRYREDLMAGIIIAGWDPQEGG-QVYSVPM 149 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G V + G Y + +D YR MT +E L + +R + + Sbjct: 150 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRL 209 Query: 182 KIVDKDGIR 190 + + G+ Sbjct: 210 AAIQQSGVE 218 >6EPF-5 nrPDB Length = 263 Score = 188 bits (478), Expect = 1e-48, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 4/191 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + Q VI+A+ T G + + K +++P+ L + AG A D + + Sbjct: 60 TTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 119 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++Y +R +S A S + + + + +I G+DK+ P LY +D Sbjct: 120 RQCRIYELRNKERISVAAASKLLANMVYQ--YKGMGLSMGTMICGWDKR--GPGLYYVDS 175 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G ++ + G Y F ++D Y D+ EE DL + + + R V + Sbjct: 176 EGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNL 235 Query: 182 KIVDKDGIRQV 192 V +DG +V Sbjct: 236 YHVREDGWIRV 246 >5GJQ-a nrPDB Length = 239 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 69/189 (36%), Gaps = 4/189 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ ++ V+L + T G + DK + +G A DT A+ + Sbjct: 35 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 94 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + +SI + +S ++ R R ++I G+D ++ ++Y + Sbjct: 95 YQLGFHSIELNEPPLVHTAASLFKEM---CYRYREDLMAGIIIAGWDPQEGG-QVYSVPM 150 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G V + G Y + +D YR MT EE L + +R + + Sbjct: 151 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRL 210 Query: 182 KIVDKDGIR 190 + + G+ Sbjct: 211 AAIAESGVE 219 >5FMG-I nrPDB Length = 229 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 51/196 (26%), Positives = 90/196 (45%), Gaps = 7/196 (3%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ Q++VIL + T G V + K +S + + AG AGD ++Q Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQV-NVLIGGYDKKKNKPELYQID 120 N++L+ + + + S + QEL K + Y+V +++GG D N P+LY I Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFK----YQGYKVCAIVLGGVD--VNGPQLYGIH 114 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 G+ LP+ A G ++L+ YR +MT EEG +L+ + V Sbjct: 115 PHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVD 174 Query: 181 VKIVDKDGIRQVDDFQ 196 + ++ KD + + ++ Sbjct: 175 ICVITKDSYQHIRPYK 190 >5LEZ-N nrPDB Length = 205 Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 69/189 (36%), Gaps = 4/189 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ ++ V+L + T G + DK + +G A DT A+ + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 + +SI + +S ++ R R ++I G+D ++ ++Y + Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEM---CYRYREDLMAGIIIAGWDPQEGG-QVYSVPM 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G V + G Y + +D YR MT EE L + +R + + Sbjct: 117 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRL 176 Query: 182 KIVDKDGIR 190 + + G+ Sbjct: 177 AAIAESGVE 185 >5LN3-5 nrPDB Length = 263 Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 4/191 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + + VI+A+ T G + + K +++P+ L + AG A D + + Sbjct: 60 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 119 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++Y +R +S A S + + + + +I G+DK+ P LY +D Sbjct: 120 RQCRIYELRNKERISVAAASKLLANMVYQ--YKGMGLSMGTMICGWDKR--GPGLYYVDS 175 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G ++ + G Y + ++D Y D+ E+ DL + + + R V + Sbjct: 176 EGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNL 235 Query: 182 KIVDKDGIRQV 192 V +DG +V Sbjct: 236 YHVREDGWIRV 246 >5FGI-H nrPDB Length = 244 Score = 184 bits (468), Expect = 1e-47, Method: Composition-based stats. Identities = 41/183 (22%), Positives = 79/183 (43%), Gaps = 5/183 (2%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 I+G++ + V++A+ T+G V + K ++SP + AG A DT + I + Sbjct: 14 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGS 73 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 NI+L+S+ E + ++Q L K + +++ G D L+ I Sbjct: 74 NIELHSLYTSREPRVVSALQMLKQHLFK---YQGHIGAYLIVAGVDP--TGSHLFSIHAH 128 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 G+ Y + G ++L+ H++ D+T EE + L +Q V V Sbjct: 129 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVC 188 Query: 183 IVD 185 +++ Sbjct: 189 VME 191 >6HV7-H nrPDB Length = 226 Score = 184 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 42/184 (22%), Positives = 73/184 (39%), Gaps = 5/184 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I G+ QD VIL + T V S +K ++P AG A D + I Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +NI+L+S+ E + ++Q L K + +++ G D L+ I Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFK---YQGHIGAYLIVAGVDP--TGSHLFSIHA 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ Y + G ++L+ H++ D+T EE + L +Q V V Sbjct: 116 HGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 175 Query: 182 KIVD 185 +++ Sbjct: 176 CVME 179 >3UNE-I nrPDB Length = 205 Score = 183 bits (464), Expect = 5e-47, Method: Composition-based stats. Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 3/187 (1%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 ++ ++ ++ V +A+ + ++ K + + AG A D A+ ++ Sbjct: 11 VMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFR 70 Query: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 + LY ++E ++ P + S V L + + PY +I G D K KP + +D +G Sbjct: 71 LNLYELKEGRQIKPYTLMSMVANLLYE--KRFGPYYTEPVIAGLDPKTFKPFICSLDLIG 128 Query: 124 T-KVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 V + G + + + + P+M E + + + R + GVIV Sbjct: 129 CPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVH 188 Query: 183 IVDKDGI 189 +++KD I Sbjct: 189 VIEKDKI 195 >3UNB-K nrPDB Length = 205 Score = 180 bits (458), Expect = 2e-46, Method: Composition-based stats. Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 4/191 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + VI+A+ T G + + K +++P+ L + AG A D + + Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++Y +R +S A S + + + + +I G+DK+ P LY +D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQ--YKGMGLSMGTMICGWDKR--GPGLYYVDS 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G ++ + G Y + ++D Y D+ EE DL + + + R V + Sbjct: 117 EGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNL 176 Query: 182 KIVDKDGIRQV 192 V +DG +V Sbjct: 177 YHVREDGWIRV 187 >3IPM-H nrPDB Length = 217 Score = 177 bits (448), Expect = 4e-45, Method: Composition-based stats. Identities = 52/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI ++D+VI+A+ + VT ++ + K Q+ +T M+ AG GD Y++ Sbjct: 9 TTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYMK 68 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 A ++LY ++ + +AV++ + L + PY V +L+GG D P ++ ID Sbjct: 69 AELELYRLQRRVNMPIEAVATLLSNMLNQV--KYMPYMVQLLVGGID---TAPHVFSIDA 123 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G VE Y + G + + +L+ Y MT +EG+DL+ + ++R + V Sbjct: 124 AGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMIDV 183 Query: 182 KIVD-KDGIRQV 192 ++ KDG Q+ Sbjct: 184 AVITRKDGYVQL 195 >6HEC-1 nrPDB Length = 202 Score = 176 bits (447), Expect = 5e-45, Method: Composition-based stats. Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 5/194 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +G+ +D V++A+ K T G + + K Q++ M+ AG GD A I+ Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 LY IR + + + +A+++ L PY V +LIGG D + +Y ID Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNS--YRYFPYLVQLLIGGIDSE--GKSIYSIDP 116 Query: 122 LGTKVEL-PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 +G +E A G + +L+ + P++ +E ++L + KR G+ Sbjct: 117 IGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGID 176 Query: 181 VKIVDKDGIRQVDD 194 V + +D Q Sbjct: 177 VVKITEDEFYQYSP 190 >5FMG-L nrPDB Length = 211 Score = 172 bits (436), Expect = 8e-44, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 87/191 (45%), Gaps = 4/191 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 L + +D +I+A + G + + +K +++ + L + AG A D + + +Y+ Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 I++Y +R + ++S +A S+ + L + +++ GYD ++ +D Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGY--GLCCGIILSGYDH--TGFNMFYVDD 116 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G KVE + G Y +S+LD Y ++ ++ ++L + + R V V Sbjct: 117 SGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRV 176 Query: 182 KIVDKDGIRQV 192 + K+G ++ Sbjct: 177 FHIHKNGYDKI 187 >6EPE-7 nrPDB Length = 263 Score = 169 bits (428), Expect = 8e-43, Method: Composition-based stats. Identities = 42/204 (20%), Positives = 83/204 (40%), Gaps = 13/204 (6%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +LG++ V++A+ + G + + +++ T++ +G+ D Y++ Sbjct: 53 TSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQ----YLK 108 Query: 62 ANIQLYSIRE-----DYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPEL 116 + I E + SP+A+ S++ + + P +IGGY + L Sbjct: 109 QVLGQMVIDEELFGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGY--AGGESFL 166 Query: 117 YQIDYLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCVQELEKRMPM 174 +D LG E P A GY + LL +P ++ E +L++ C++ L R Sbjct: 167 GYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLYYRDAR 226 Query: 175 DFKGVIVKIVDKDGIRQVDDFQAQ 198 + V V + G+ AQ Sbjct: 227 SYNRFQVATVTEKGVEIEGPLSAQ 250 >5FMG-K nrPDB Length = 195 Score = 166 bits (421), Expect = 5e-42, Method: Composition-based stats. Identities = 63/191 (32%), Positives = 107/191 (56%), Gaps = 3/191 (1%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDD-KTRQLSPHTLMSFAGEAGDTVQFAEY 59 MD ++G+R + V+LA+ I LK+ D+ K + + + G GD +QF E+ Sbjct: 1 MDTLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEF 60 Query: 60 IQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 I+ N+ LY + + ++ ++ + F R+ LA +R R P++VN LI GYDKK +LY Sbjct: 61 IRKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLR-RNPFEVNCLIAGYDKKD-GYQLYWC 118 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 DYL + GAHGY + ++LD +Y ++T +E LD+ KLC +EL+KR + Sbjct: 119 DYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINY 178 Query: 180 IVKIVDKDGIR 190 ++I+ + + Sbjct: 179 ELRIMYDNKVE 189 >4Y8P-I nrPDB Length = 205 Score = 166 bits (420), Expect = 6e-42, Method: Composition-based stats. Identities = 38/190 (20%), Positives = 76/190 (40%), Gaps = 4/190 (2%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 I++ + +D V +A + + + +K H + G A D E + Sbjct: 11 IVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEMFRY 69 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 LY ++E+ + P+ + V L + R PY V ++ G + K KP + D + Sbjct: 70 KTNLYKLKEERAIEPETFTQLVSSSLYE--RRFGPYFVGPVVAGINSKSGKPFIAGFDLI 127 Query: 123 GTKVEL-PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G E + G + F + + Y P++ E+ + + + R + G +V Sbjct: 128 GCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVV 187 Query: 182 KIVDKDGIRQ 191 I+ KD + + Sbjct: 188 YIIKKDEVVK 197 >5MPC-h nrPDB Length = 215 Score = 165 bits (419), Expect = 8e-42, Method: Composition-based stats. Identities = 45/191 (23%), Positives = 87/191 (45%), Gaps = 5/191 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ + +D VIL + T G + DK ++ +G A DT A+ +Q Sbjct: 20 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQ 79 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +++LY+ + + A S F +EL ++ +++ GYD K NK E+Y I Sbjct: 80 YHLELYTSQYGTPSTETAASVF--KEL--CYENKDNLTAGIIVAGYDDK-NKGEVYTIPL 134 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G+ +LPY G + + D ++R +M+ EE +D +K + + K + + Sbjct: 135 GGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRM 194 Query: 182 KIVDKDGIRQV 192 ++ G+ ++ Sbjct: 195 VVLTAAGVERL 205 >4YA5-C nrPDB Length = 254 Score = 165 bits (417), Expect = 1e-41, Method: Composition-based stats. Identities = 40/188 (21%), Positives = 86/188 (45%), Gaps = 8/188 (4%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +G++ ++ V+L + T + + + K ++ H ++SF+G D+ E + Sbjct: 34 VGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILIEKARVEA 93 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQIDYL 122 Q + + + ++ + ++ +V + +S RP+ V+ LI G+D + ++P+LYQ + Sbjct: 94 QSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPS 153 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHY---RPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 G G + L+ +Y P T EE +KL V+ L + + K + Sbjct: 154 GIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEE---CVKLTVRSLLEVVQTGAKNI 210 Query: 180 IVKIVDKD 187 + +V D Sbjct: 211 EITVVKPD 218 >5GJQ-g nrPDB Length = 264 Score = 163 bits (412), Expect = 5e-41, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 83/200 (41%), Gaps = 5/200 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +LG++ + V++A+ + G + + +++ T++ +G+ D + + Sbjct: 54 TSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLG 113 Query: 62 A-NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 I + + + SP+A+ S++ + + P ++IGGY + L +D Sbjct: 114 QMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGESFLGYVD 171 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCVQELEKRMPMDFKG 178 LG E P A GY + LL +P ++ E DL++ C++ L R + Sbjct: 172 MLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNR 231 Query: 179 VIVKIVDKDGIRQVDDFQAQ 198 + V + G+ + Sbjct: 232 FQIATVTEKGVEIEGPLSTE 251 >5LF6-M nrPDB Length = 219 Score = 160 bits (406), Expect = 2e-40, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 83/200 (41%), Gaps = 5/200 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +LG++ + V++A+ + G + + +++ T++ +G+ D + + Sbjct: 9 TSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLG 68 Query: 62 A-NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 I + + + SP+A+ S++ + + P ++IGGY + L +D Sbjct: 69 QMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGESFLGYVD 126 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDH--HYRPDMTTEEGLDLLKLCVQELEKRMPMDFKG 178 LG E P A GY + LL +P ++ E DL++ C++ L R + Sbjct: 127 MLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNR 186 Query: 179 VIVKIVDKDGIRQVDDFQAQ 198 + V + G+ + Sbjct: 187 FQIATVTEKGVEIEGPLSTE 206 >5FMG-N nrPDB Length = 265 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 46/231 (19%), Positives = 89/231 (38%), Gaps = 37/231 (16%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI- 60 ++ I+ + +++A+ + + G + ++ +++ T+M F+GE D E + Sbjct: 10 TSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLHELLT 69 Query: 61 QANIQLYSIREDYE--LSPQAVSSFVRQELAKSIRSRRPYQVNVLIGG-----YDKKKNK 113 + NI S ++ E +PQ S+V + P N++I G YD + Sbjct: 70 RKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYDNNDDN 129 Query: 114 PELYQ-----------------------------IDYLGTKVELPYGAHGYSGFYTFSLL 144 LY +D GT Y GY+ ++ +LL Sbjct: 130 VLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFALTLL 189 Query: 145 DHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 195 HY+ +MT EE L+ C++ L R + + V G+ + + Sbjct: 190 RDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPY 240 >3H4P-A nrPDB Length = 264 Score = 155 bits (393), Expect = 8e-39, Method: Composition-based stats. Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 7/172 (4%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI +D V+LA + +T + + S +K Q+ H + +G D + + Sbjct: 39 TTAIGIACKDGVVLAVDRRITSKLVKI-RSIEKIFQIDDHVAAATSGLVADARVLIDRAR 97 Query: 62 ANIQLYSIREDYELSPQAVSS---FVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 Q+Y + E+S + ++ ++Q + RP+ V++LI G DK N+ L++ Sbjct: 98 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH-GGVRPFGVSLLIAGIDK--NEARLFE 154 Query: 119 IDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 D G +E A G LL+ YR D+T +EGL+L + + + Sbjct: 155 TDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANE 206 >5FMG-E nrPDB Length = 256 Score = 155 bits (393), Expect = 9e-39, Method: Composition-based stats. Identities = 46/195 (23%), Positives = 84/195 (43%), Gaps = 13/195 (6%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI V D VILAS + ++ + + KDS +K + H + +G D +Y + Sbjct: 35 STAVGICVNDGVILASERRISSTL-IEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYAR 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQ------ELAKSIRSR---RPYQVNVLIGGYDKKKN 112 Y + ++ ++ + + L+ S R + RP+ V +LIGG DK N Sbjct: 94 VECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVDK--N 151 Query: 113 KPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRM 172 P L+ + GT + G + LL +Y+ DMT E+ L ++++ + Sbjct: 152 GPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVME-D 210 Query: 173 PMDFKGVIVKIVDKD 187 + V + + K Sbjct: 211 KLSTSNVEICAIKKS 225 >6AVO-A nrPDB Length = 199 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 34/188 (18%), Positives = 72/188 (38%), Gaps = 5/188 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ + V++ S V+ G +V+ DK L + +G A D A+ Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++L+ I + A ++ VR S + R ++++ G+D+++ ++Y Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNI---SYKYREDLSAHLMVAGWDQREGG-QVYGT-L 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G P+ G + + +D Y+P M+ EE + R + + Sbjct: 116 GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYL 175 Query: 182 KIVDKDGI 189 + G+ Sbjct: 176 VTITAAGV 183 >5LEZ-C nrPDB Length = 248 Score = 150 bits (379), Expect = 3e-37, Method: Composition-based stats. Identities = 39/188 (20%), Positives = 78/188 (41%), Gaps = 5/188 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +G+R +D V+L K + + K L + M+FAG D + Sbjct: 30 STAVGVRGRDIVVLGVEKKSVAKLQDE-RTVRKICALDDNVCMAFAGLTADARIVINRAR 88 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRS--RRPYQVNVLIGGYDKKKNKPELYQI 119 Q + + + ++ + ++ ++ + +S RRP+ ++ LI G+D P LYQ Sbjct: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD-FDGTPRLYQT 147 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 D GT A G L+ +Y + + L +KL ++ L + + K + Sbjct: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDL-TIKLVIKALLEVVQSGGKNI 206 Query: 180 IVKIVDKD 187 + ++ +D Sbjct: 207 ELAVMRRD 214 >5GJR-F nrPDB Length = 241 Score = 149 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 43/194 (22%), Positives = 80/194 (41%), Gaps = 15/194 (7%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI+ + V LA K +T + + S +K ++ H + +G D + + Sbjct: 35 STAIGIQTSEGVCLAVEKRITSPL-MEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKAR 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQ-------ELAKSIRSRRPYQVNVLIGGYDKKKNKP 114 Q + + ++ ++V+ V E A RP+ V +L GG D+K P Sbjct: 94 VETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEK--GP 151 Query: 115 ELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMP- 173 +L+ +D GT V+ A G + S L Y MT +E +K + L++ M Sbjct: 152 QLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEA---IKSSLIILKQVMEE 208 Query: 174 -MDFKGVIVKIVDK 186 ++ + + V Sbjct: 209 KLNATNIELATVQP 222 >6HE5-A nrPDB Length = 247 Score = 144 bits (363), Expect = 3e-35, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 71/165 (43%), Gaps = 6/165 (3%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 +GI+ ++ VIL + K V + + +K ++ H + +G D + + Sbjct: 37 TAIGIKCKEGVILIADKRVGSKLLEAD-TIEKIYKIDEHICAATSGLVADARVLIDRARI 95 Query: 63 NIQLYSIREDYELSPQAVSSFVR--QELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Q+ + D ++ + ++ + ++ RP+ V++LI G D+ P+LY+ D Sbjct: 96 EAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV---PKLYETD 152 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCV 165 G +E A G + YR D++ ++ + L + + Sbjct: 153 PSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAM 197 >5FMG-C nrPDB Length = 246 Score = 141 bits (355), Expect = 2e-34, Method: Composition-based stats. Identities = 52/194 (26%), Positives = 81/194 (41%), Gaps = 12/194 (6%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I +G+ +D VIL + K + ++ +K ++ H AG D Sbjct: 32 SITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILIN--- 88 Query: 62 ANIQLYSIREDYEL-SPQAVSSFVRQ--ELAKSIRSR---RPYQVNVLIGGYDKKKNKPE 115 +LY+ R Y Q VS V Q ++ +S RPY V+ LIGGYD K + + Sbjct: 89 -QSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTK-DGYQ 146 Query: 116 LYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMD 175 LY D G A G + S+L ++ DMT EEGL L + + Sbjct: 147 LYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEIPK 206 Query: 176 FKGVIV-KIVDKDG 188 + + + + +KDG Sbjct: 207 SEKIELAYLTNKDG 220 >3UNF-N nrPDB Length = 199 Score = 140 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 34/188 (18%), Positives = 73/188 (38%), Gaps = 5/188 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ + V++ S V+ G +V+ DK L + +G A D A+ Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 ++L+ + + A ++ V+ S + R ++++ G+D+++ ++Y Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNI---SYKYREDLLAHLIVAGWDQREGG-QVYGT-M 115 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 G + P+ G Y + +D Y+P MT EE + R + + Sbjct: 116 GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 175 Query: 182 KIVDKDGI 189 + G+ Sbjct: 176 VTITAAGV 183 >1G0U-D nrPDB Length = 241 Score = 137 bits (346), Expect = 3e-33, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 3/193 (1%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI ++ V+L K T + + DS +K ++ H + +G D E+ + Sbjct: 35 STAIGIATKEGVVLGVEKRATSPL-LESDSIEKIVEIDRHIGCAMSGLTADARSMIEHAR 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +++ D +++ ++++ V +LA + RP+ V +LI G+D + +L+ + Sbjct: 94 TAAVTHNLYYDEDINVESLTQSVC-DLAAAAAMSRPFGVALLIAGHD-ADDGYQLFHAEP 151 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 GT A G + L + + +T +E L+ ++++ + + + Sbjct: 152 SGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLS 211 Query: 182 KIVDKDGIRQVDD 194 I +DG + D+ Sbjct: 212 CITKQDGFKIYDN 224 >2Z5C-C nrPDB Length = 262 Score = 132 bits (333), Expect = 8e-32, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 82/201 (40%), Gaps = 10/201 (4%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI ++ V+L K T + + DS +K ++ H + +G D E+ + Sbjct: 37 STAIGIATKEGVVLGVEKRATSPL-LESDSIEKIVEIDRHIGCAMSGLTADARSMIEHAR 95 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRS--------RRPYQVNVLIGGYDKKKNK 113 +++ D +++ ++++ V + RP+ V +LI G+D + Sbjct: 96 TAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHD-ADDG 154 Query: 114 PELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMP 173 +L+ + GT A G + L + + +T +E L+ ++++ + Sbjct: 155 YQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKL 214 Query: 174 MDFKGVIVKIVDKDGIRQVDD 194 + + I +DG + D+ Sbjct: 215 DENNAQLSCITKQDGFKIYDN 235 >5FMG-D nrPDB Length = 241 Score = 126 bits (317), Expect = 6e-30, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 77/192 (40%), Gaps = 7/192 (3%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 + I+ + +LA K + + +K +L H ++FAG D + Sbjct: 33 VAIKSSNFAVLAVEKKNIPKLQ-NPKTTEKLIKLDEHNCLAFAGLNADARVLVNKTRLEC 91 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQIDYL 122 Q Y + D ++ +V + K RP+ + LI G+ K + +YQ + Sbjct: 92 QRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGF-KNNKEICIYQTEPS 150 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 G A G + L+ +Y+ +M E D + L ++ + + + + K V V Sbjct: 151 GIYAAWKAQAIGKNAKIVQEFLEKNYQENM---EQKDCIFLALKAIFEVVELSSKNVEVA 207 Query: 183 IVDKDGIRQVDD 194 ++ + + +++ Sbjct: 208 LLTEKDLTFIEE 219 >6J30-C nrPDB Length = 258 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 72/186 (38%), Gaps = 3/186 (1%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 +GI D ++LA+ + VT + S +K +L+ ++ AG D + Sbjct: 34 TAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARI 93 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQID 120 + Q Y + ++ + + + + RP+ V+ + GYD + +LY + Sbjct: 94 HAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRY-GYQLYTSN 152 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 G + G + +LL Y+ DM ++ ++L + + + + + Sbjct: 153 PSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTYDRLE 212 Query: 181 VKIVDK 186 + K Sbjct: 213 FATIRK 218 >5L4G-U nrPDB Length = 241 Score = 119 bits (298), Expect = 8e-28, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 12/199 (6%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 IL I +D I+AS ++ G S+ K +L+ T++ +G GD + + I+A Sbjct: 39 TILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEA 98 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 +++Y + ++ A+++ + L R PY V +IGG D+ + K +Y D + Sbjct: 99 RLKMYKHSNNKAMTTGAIAAMLSTILYS--RRFFPYYVYNIIGGLDE-EGKGAVYSFDPV 155 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHY---------RPDMTTEEGLDLLKLCVQELEKRMP 173 G+ + A G + LLD+ ++ + + L+K +R Sbjct: 156 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDV 215 Query: 174 MDFKGVIVKIVDKDGIRQV 192 + + IV K+GIR+ Sbjct: 216 YTGDALRICIVTKEGIREE 234 >5VFT-S nrPDB Length = 213 Score = 118 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 12/199 (6%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 IL I +D I+AS ++ G S+ K +L+ T++ +G GD + + I+A Sbjct: 11 TILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEA 70 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 +++Y + ++ A+++ + L R PY V +IGG D+ + K +Y D + Sbjct: 71 RLKMYKHSNNKAMTTGAIAAMLSTILYS--RRFFPYYVYNIIGGLDE-EGKGAVYSFDPV 127 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHY---------RPDMTTEEGLDLLKLCVQELEKRMP 173 G+ + A G + LLD+ ++ + + L+K +R Sbjct: 128 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDV 187 Query: 174 MDFKGVIVKIVDKDGIRQV 192 + + IV K+GIR+ Sbjct: 188 YTGDALRICIVTKEGIREE 206 >2KU2-A nrPDB Length = 237 Score = 117 bits (293), Expect = 3e-27, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 71/171 (41%), Gaps = 5/171 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 LG++ + V+L S K V + + ++S +K + + + +G D ++ + Sbjct: 39 STALGMKFANGVLLISDKKVRSRL-IEQNSIEKIQLIDDYVAAVTSGLVADARVLVDFAR 97 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKS--IRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + Q + ++ + + V ++ + RPY V+++ G D+ P L+ Sbjct: 98 ISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQI--GPRLFDC 155 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 D GT E A G S L+ Y+ ++ +E + L ++ + Sbjct: 156 DPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLE 206 >6EPF-6 nrPDB Length = 240 Score = 116 bits (291), Expect = 5e-27, Method: Composition-based stats. Identities = 45/199 (22%), Positives = 87/199 (43%), Gaps = 12/199 (6%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 +L I +D I+AS ++ G S+ K +L+ T++ +G GD + + I+A Sbjct: 38 TVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEA 97 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 +++Y + ++ A+++ + L R PY V +I G D+ + K +Y D + Sbjct: 98 RLKMYKHSNNKAMTTGAIAAMLSTILYS--RRFFPYYVYNIIEGLDE-EGKGAVYSFDPV 154 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHY---------RPDMTTEEGLDLLKLCVQELEKRMP 173 G+ + A G + LLD+ +T + + L+K +R Sbjct: 155 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDV 214 Query: 174 MDFKGVIVKIVDKDGIRQV 192 + + IV K+GIR+ Sbjct: 215 YTGDALRICIVTKEGIREE 233 >5FMG-J nrPDB Length = 218 Score = 116 bits (290), Expect = 8e-27, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 77/201 (38%), Gaps = 15/201 (7%) Query: 4 ILGIRVQDSVILASSKAVTRGISV-LKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 +LG+ + V +A + + K +++ + + +G A D E ++ Sbjct: 12 VLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYEILRY 71 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGG------YDKKKNK--- 113 + LY +R+D E+ + ++ + L PY VN ++ G D++ K Sbjct: 72 RVNLYEVRQDAEMDVECFANMLSSILYS--NRFSPYFVNPIVVGFKLKHYVDEEGEKKVN 129 Query: 114 --PELYQIDYLGTKVEL-PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 P L D +G K E + +G + F + + Y D + + C+ Sbjct: 130 YEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSALD 189 Query: 171 RMPMDFKGVIVKIVDKDGIRQ 191 R + G V ++ + I + Sbjct: 190 RDCISGWGAEVLVLTPEKIIK 210 >5LE5-B nrPDB Length = 261 Score = 115 bits (288), Expect = 1e-26, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 72/189 (38%), Gaps = 6/189 (3%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 LGI D V+LA+ + + +K +L+ S AG D ++ Sbjct: 33 TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRL 92 Query: 63 NIQLYSIREDYELSPQ---AVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 Q Y ++ + + ++Q + +RP+ V++L G+DK +LYQ Sbjct: 93 IAQRYLLQYQEPIPCEQLVTALCDIKQAYTQ-FGGKRPFGVSLLYIGWDKHY-GFQLYQS 150 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRP-DMTTEEGLDLLKLCVQELEKRMPMDFKG 178 D G G + S+L Y+ +MT + L L + + + + Sbjct: 151 DPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEK 210 Query: 179 VIVKIVDKD 187 V + + ++ Sbjct: 211 VEIATLTRE 219 >5LF0-A nrPDB Length = 234 Score = 114 bits (286), Expect = 2e-26, Method: Composition-based stats. Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 6/196 (3%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 +GI+ + V+LA+ K + S K ++ H + ++G D + Sbjct: 36 VGIKAANGVVLATEKKQKSILYDE-RSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLA 94 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQIDYL 122 Q Y + + + V + + +S RP+ V++LI G++ + +P L+Q D Sbjct: 95 QQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWN--EGRPYLFQSDPS 152 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 G A G + + L+ Y D+ E+ + L ++E + M + V Sbjct: 153 GAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFE-GQMTEDNIEVG 211 Query: 183 IVDKDGIRQVDDFQAQ 198 I ++ G R++ + + Sbjct: 212 ICNEAGFRRLTPTEVK 227 >5FMG-B nrPDB Length = 235 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 5/168 (2%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 LGIR ++ VI+A+ K + + ++S K +Q+S H + +AG GD + + Sbjct: 36 LGIRAKNGVIIATEKKSPNEL-IEENSIFKIQQISEHIGIVYAGMPGDFRVLLKRARKEA 94 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIR--SRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 YS++ E+ + + + + + + RP+ +++LI G D LYQID Sbjct: 95 IRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVY--GYHLYQIDPS 152 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 G G S L+ Y D+ E+ + L ++E + Sbjct: 153 GCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYE 200 >5FMG-M nrPDB Length = 240 Score = 112 bits (279), Expect = 1e-25, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 76/195 (38%), Gaps = 11/195 (5%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 ++G+ +D VILA+ ++ S+ K +L+ ++ +G D +Q Sbjct: 39 TVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSLLQK 98 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 IQL+ + + ++ + L R PY ++ G D+ NK LY D + Sbjct: 99 KIQLFVLEHSHYPDIHVIARLLCVILYS--RRFFPYYAFNILAGVDE-NNKGVLYNYDSV 155 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYRP--------DMTTEEGLDLLKLCVQELEKRMPM 174 G+ E + G +LD+ + + ++ +K + +R Sbjct: 156 GSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERDIY 215 Query: 175 DFKGVIVKIVDKDGI 189 ++ ++DK GI Sbjct: 216 TGDKTLIYVIDKMGI 230 >4FZC-A nrPDB Length = 250 Score = 112 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 81/188 (43%), Gaps = 6/188 (3%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 LGI+ + V++A+ K + +++ + + K L+P ++G D + + Sbjct: 33 TSLGIKATNGVVIATEKKSSSPLAMSE-TLSKVSLLTPDIGAVYSGMGPDYRVLVDKSRK 91 Query: 63 NIQL-YSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQI 119 Y + + S V + + ++ +S RP+ V++LI G+D+ N LYQ+ Sbjct: 92 VAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEF-NGFSLYQV 150 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGV 179 D G+ A G + L+ + ++ E+ + + L ++E + + + Sbjct: 151 DPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVE-GEFNGDTI 209 Query: 180 IVKIVDKD 187 + I+ + Sbjct: 210 ELAIIGDE 217 >6GOP-M nrPDB Length = 246 Score = 105 bits (263), Expect = 1e-23, Method: Composition-based stats. Identities = 28/208 (13%), Positives = 76/208 (36%), Gaps = 12/208 (5%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 ++ ++ + VI+A+ + G + + ++ + +T++ +G+ D ++ Sbjct: 22 TSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERLLK 81 Query: 62 ANIQLYSIRE-----DYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPEL 116 + + + L P + ++ + + P +++ G ++ L Sbjct: 82 DLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQSNGDQ-FL 140 Query: 117 YQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYR-----PDMTTEEGLDLLKLCVQELEKR 171 ++ LG P A G+ LL P T + + + ++ L R Sbjct: 141 RYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRVLYYR 200 Query: 172 MPMDFKGVIVKIVDKD-GIRQVDDFQAQ 198 + + I+DK+ G+ + Q + Sbjct: 201 DARSSRNFSLAIIDKNTGLTFKKNLQVE 228 >3NZW-L nrPDB Length = 241 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 46/208 (22%), Positives = 81/208 (38%), Gaps = 21/208 (10%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 ILGI +D +LA S+ + K + +MS G A D + + Sbjct: 30 TILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKN 89 Query: 63 NIQLYSIR-EDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 +++ Y D +LS + + ++ L + PY V+ +I G D+ K +Y D Sbjct: 90 SVKWYHFDHNDKKLSINSAARNIQHLLY--GKRFFPYYVHTIIAGLDE-DGKGAVYSFDP 146 Query: 122 LGTKVELPYGAHGYSGFYTFSLLD------HHYRPD-----------MTTEEGLDLLKLC 164 +G+ A G + LD + Y P ++ EE + L++ Sbjct: 147 VGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDS 206 Query: 165 VQELEKRMPMDFKGVIVKIVDKDGIRQV 192 +R G+ + IV KDG+R+ Sbjct: 207 FTSATERHIQVGDGLEILIVTKDGVRKE 234 >5FMG-H nrPDB Length = 252 Score = 103 bits (256), Expect = 6e-23, Method: Composition-based stats. Identities = 37/251 (14%), Positives = 78/251 (31%), Gaps = 58/251 (23%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI- 60 I+GI + V+LA + G + K +++ + + +G + + + E I Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 61 ----------QANIQLYSIR---------------------------------------- 70 + + + Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 71 --EDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVEL 128 DY + V+ ++ + + ++ GGYD K K +LY ++ G+ +E Sbjct: 121 KFNDYNPLVENVAHITKKII---YTNNNFLSCALIFGGYD-KIKKQQLYAVNLNGSIIEK 176 Query: 129 -PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKD 187 + G Y S L Y+ MT +E +L+ CV+ + + + K Sbjct: 177 HDFAVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKS 236 Query: 188 GIRQVDDFQAQ 198 + + Q Sbjct: 237 FVEEFTVVNTQ 247 >6FVW-g nrPDB Length = 245 Score = 100 bits (250), Expect = 3e-22, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 8/174 (4%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI+ D V+ A K +T + V + + K + + H ++G D + Sbjct: 32 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 90 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKS--IRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + + A + + Q + S RP+ V+ + GG DK N LY + Sbjct: 91 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK--NGAHLYML 148 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDH---HYRPDMTTEEGLDLLKLCVQELEK 170 + G+ A G + L+ H+ ++ E + + + Sbjct: 149 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 202 >5FGG-F nrPDB Length = 288 Score = 100 bits (249), Expect = 4e-22, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 8/174 (4%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GI+ D V+ A K +T + V + + K + + H ++G D + Sbjct: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKS--IRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + + A + + Q + S RP+ V+ + GG DK N LY + Sbjct: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK--NGAHLYML 151 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDH---HYRPDMTTEEGLDLLKLCVQELEK 170 + G+ A G + L+ H+ ++ E + + + Sbjct: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 >5T0I-L nrPDB Length = 268 Score = 91.6 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 67/189 (35%), Gaps = 10/189 (5%) Query: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 +G++ + +L + K ++ + K + H +S AG D +++ Sbjct: 40 TVGLKSKTHAVLVALKRAQSELAAHQK---KILHVDNHIGISIAGLTADARLLCNFMRQE 96 Query: 64 IQLYSIREDYELSPQAVSSFV--RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 D L + S + + ++ RRPY V +LI GYD P ++Q Sbjct: 97 CLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYD--DMGPHIFQTCP 154 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDM--TTEEGLDLLKLCVQELEKRMP-MDFKG 178 + + G + L+ H M E + ++E + K Sbjct: 155 SANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQDLTTKN 214 Query: 179 VIVKIVDKD 187 V + IV KD Sbjct: 215 VSIGIVGKD 223 >5FMG-F nrPDB Length = 254 Score = 87.8 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 75/169 (44%), Gaps = 13/169 (7%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 + I+ +D V+++ K +S + +K ++ + +S +G D +++Q Sbjct: 36 VAIKSKDYVVVSGLKKCISKLSFPQ---EKIFKIDDYIGISMSGITSDAKVLTKFMQNEC 92 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIR--SRRPYQVNVLIGGYDKKKNKPELYQIDYL 122 + + ++ +++ V + K+ + S+R + V ++I Y N+P +++ Sbjct: 93 LSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFGVGLMIAAY---HNEPCIFETRPN 149 Query: 123 GTKVELPYGAHGYSGFYTFSLLDHHYR--PDMTTEEGLDLLKLCVQELE 169 G+ E + G + + L+ + + + EE L+ C++ L+ Sbjct: 150 GSYFEYDALSFGARSHASKTYLEKNLHLFEECSLEE---LILHCLKALK 195 >1Q5Q-H nrPDB Length = 235 Score = 87.8 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 32/183 (17%), Positives = 62/183 (33%), Gaps = 7/183 (3%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ + + V+LA + T+G + +K ++ AG AG ++ Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRR-PYQVNVLIGGY----DKKKNKPEL 116 ++ Y E L+ ++ + + ++ + V L+ GY D + + Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 117 YQIDYLGTKVE--LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPM 174 D +G + E Y A G + S L Y PD E L + + Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 175 DFK 177 Sbjct: 181 TGG 183 >1IRU-A nrPDB Length = 246 Score = 87.8 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 26/188 (13%), Positives = 67/188 (35%), Gaps = 9/188 (4%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 + +R +D ++ + K V + +++ + G D+ + + Sbjct: 38 TSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH-LFKITENIGCVMTGMTADSRSQVQRARY 96 Query: 63 NIQLYSIREDYELSPQAVSSFVRQELAKSIRSR---RPYQVNVLIGGYDKKKNKPELYQI 119 + + YE+ + + ++++ RP +++ G D+ + P++Y+ Sbjct: 97 EAANWKYKYGYEIPVDMLCKRIA-DISQVYTQNAEMRPLGCCMILIGIDE-EQGPQVYKC 154 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRP--DMTTEEGLDLLKLCVQELEKRMPMDFK 177 D G A G + S L+ + D T E+ ++ C+ + Sbjct: 155 DPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSID-FKPS 213 Query: 178 GVIVKIVD 185 + V +V Sbjct: 214 EIEVGVVT 221 >6EPD-G nrPDB Length = 255 Score = 87.4 bits (215), Expect = 4e-18, Method: Composition-based stats. Identities = 28/171 (16%), Positives = 60/171 (35%), Gaps = 4/171 (2%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 +GIR +D V+ K V + + + + H M+ AG D A+ + Sbjct: 35 STAIGIRCKDGVVFGVEKLVLSKLYEEGSN-KRLFNVDRHVGMAVAGLLADARSLADIAR 93 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQ--ELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + Y + + ++ V + RP+ + ++G Y + +LY I Sbjct: 94 EEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSY-SVNDGAQLYMI 152 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 D G A G + + ++ +MT + + + + + Sbjct: 153 DPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHD 203 >1Q5R-H nrPDB Length = 294 Score = 86.6 bits (213), Expect = 6e-18, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 63/186 (33%), Gaps = 13/186 (6%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ + + V+LA + T+G + + ++ AG AG ++ Sbjct: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRLFA 125 Query: 62 ANIQLYSIREDYELS----PQAVSSFVRQELAKSIRSRRPYQVNVLIGGY----DKKKNK 113 ++ Y E L+ ++S VR L +++ V L+ GY D + Sbjct: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQ---GLAVVPLLVGYDLDADDESRA 182 Query: 114 PELYQIDYLGTKVE--LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKR 171 + D +G + E Y A G + S L Y PD E L + + Sbjct: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 Query: 172 MPMDFK 177 Sbjct: 243 DSATGG 248 >3NZW-E nrPDB Length = 234 Score = 83.9 bits (206), Expect = 4e-17, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 75/192 (39%), Gaps = 11/192 (5%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 + +G+R +L + K +S + K + H +S AG A D + Y++ Sbjct: 33 SVTVGLRSNTHAVLVALKRNADELSSYQK---KIIKCDEHMGLSLAGLAPDARVLSNYLR 89 Query: 62 ANIQLYSIREDYELSPQAVSSFVRQELAKSIRSR--RPYQVNVLIGGYDKKKNKPELYQI 119 S+ + +L+ + + + K+ +S RPY V +LI GYDK + L + Sbjct: 90 QQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDK--SGAHLLEF 147 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHY----RPDMTTEEGLDLLKLCVQELEKRMPMD 175 G EL A G + L+ + D +E + + + + + Sbjct: 148 QPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLT 207 Query: 176 FKGVIVKIVDKD 187 + + IV KD Sbjct: 208 VDNLSIAIVGKD 219 >2JAY-A nrPDB Length = 291 Score = 81.6 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 39/208 (18%), Positives = 70/208 (33%), Gaps = 20/208 (9%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQ 61 I+ ++ V++A + T+G + K +T AG A V+FA Sbjct: 58 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYA 117 Query: 62 ANIQLYSIREDYELS----PQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPE-- 115 ++ Y E L+ ++ VR LA +++ + YD + P+ Sbjct: 118 VELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAG---YDIHASDPQSA 174 Query: 116 --LYQIDYLG--TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKR 171 + D G E Y A G + S + Y + GL + + + Sbjct: 175 GRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADD 234 Query: 172 MPMDFKGVIVK-------IVDKDGIRQV 192 +V+ I+D DG V Sbjct: 235 DSATGGPDLVRGIFPTAVIIDADGAVDV 262 >5LZP-A nrPDB Length = 242 Score = 78.9 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 70/207 (33%), Gaps = 20/207 (9%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQA 62 I+ ++ V++A + T+G + K +T AG A V+FA Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 63 NIQLYSIREDYELS----PQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPE--- 115 ++ Y E L+ ++ VR LA +++ + YD + P+ Sbjct: 62 ELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAG---YDIHASDPQSAG 118 Query: 116 -LYQIDYLG--TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRM 172 + D G E Y A G + S + Y + GL + + + Sbjct: 119 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 178 Query: 173 PMDFKGVIVK-------IVDKDGIRQV 192 +V+ I+D DG V Sbjct: 179 SATGGPDLVRGIFPTAVIIDADGAVDV 205 >5FMG-G nrPDB Length = 252 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 18/161 (11%), Positives = 64/161 (39%), Gaps = 4/161 (2%) Query: 2 DIILGIRVQDSVILAS-SKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 + L + +D +I + + + + K+S ++ ++ + +++++G GD + Sbjct: 35 NTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRA 94 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQEL--AKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 ++ Y + + + + + RP+ +++I +++K ++Y Sbjct: 95 RSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKG-DIYC 153 Query: 119 IDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLD 159 I+ G + G + + ++ D+ + ++ Sbjct: 154 IEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIE 194 >5FMG-A nrPDB Length = 260 Score = 64.7 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 31/200 (15%), Positives = 69/200 (34%), Gaps = 19/200 (9%) Query: 3 IILGIRVQDSVILASSKAVTRGISVLKD-----SDDKTRQLSPHTLMSFAGEAGDTVQFA 57 +G++ ++ ++ S K + + ++ S G GD + Sbjct: 38 TSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMV 97 Query: 58 EYIQANIQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKP 114 ++ + Y ++ + + + Q + R ++I G D+ NKP Sbjct: 98 YKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMII-GIDE-NNKP 155 Query: 115 ELYQIDYLGTKVELPYGAHGYSGFYTFSLLD-------HHYRPDMTTEEGLDLLKLCVQE 167 EL++ D G G + S+L+ + + E+ + L ++ Sbjct: 156 ELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILAIEA 215 Query: 168 LEKRMPMDFKG--VIVKIVD 185 L+ + D K + V IV Sbjct: 216 LQTILAFDLKASEIEVAIVS 235 >5L5W-G nrPDB Length = 252 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 68/193 (35%), Gaps = 12/193 (6%) Query: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 L +R +D ++ S K V + + +S M G D A +A Sbjct: 43 LAVRGKDCTVVISQKKVPDKLLD-PTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEA 101 Query: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSR---RPYQVNVLIGGYDKKKNKPELYQIDY 121 + + Y++ ++ + L++ R RP V + D+ + P +Y+ D Sbjct: 102 AEFRYKYGYDMPCDVLAKRMAN-LSQIYTQRAYMRPLGVILTFVSVDE-ELGPSIYKTDP 159 Query: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYR----PDMTTEEGLDLLKLCVQELEKRM--PMD 175 G V A G + L++H++ + E +++ + + + Sbjct: 160 AGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFS 219 Query: 176 FKGVIVKIVDKDG 188 + V + KD Sbjct: 220 KNDLEVGVATKDK 232 >5LOY-A nrPDB Length = 240 Score = 60.4 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 69/209 (33%), Gaps = 25/209 (11%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPH-------TLMSFAGEAGDTV 54 +GIR+ + ++ AS G+ D+ R++ ++ AG T Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGV----DNISTFRKMHVFEVPGERVIVLLTAGNLATTQ 56 Query: 55 QFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRP--------YQVNVLIGG 106 ++ ++ R S + V + L + P + + ++GG Sbjct: 57 AVISLLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGG 116 Query: 107 YDKKKNKPELYQIDYLGTKVEL----PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 P L+ I G +E P+ G Y +LD PD + E+ Sbjct: 117 -QIAGEPPRLFLIYPAGNFIEATPDTPFFQIGE-TKYGKPILDRVITPDTSLEDAAKCAL 174 Query: 163 LCVQELEKRMPMDFKGVIVKIVDKDGIRQ 191 + + + + + ++D +R Sbjct: 175 VSFDSTMRSNLSVGLPLDLLVYERDSLRV 203 >5JI2-A nrPDB Length = 184 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 56/171 (32%), Gaps = 14/171 (8%) Query: 1 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQL-SPHTLMSFAGEAGDTVQFAEY 59 M I+ +R V++A T G +V+K + K R+L + + FAG D E Sbjct: 1 MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFEL 60 Query: 60 IQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + ++++ +A + + + + L+ D+ + Sbjct: 61 FERKLEMHQ-----GHLVKAAVELAKDWRTDRMLRK----LEALLAVADETASLIITGNG 111 Query: 120 DYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEK 170 D + E A G G Y + T ++ + + Sbjct: 112 DV--VQPENDLIAIGSGGPYAQAAARALLEN--TELSAREIAEKALDIAGD 158 >4HO7-A nrPDB Length = 179 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 72/188 (38%), Gaps = 19/188 (10%) Query: 2 DIILGIRVQDSVILASSKAVTRGI-SVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI 60 IL +R D+V+L + VT G V K S K R+++ ++ FAG D + E + Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 + I E +A ++ ++ R+ R + ++++ ++ +ID Sbjct: 61 ENKIG-----EFPNQLTRAAVELAKE--WRTDRALRRLEASLIVCSAEETL------EID 107 Query: 121 YLG---TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 G T A G G + + D+ + + + ++ + Sbjct: 108 GQGNVITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDIDVFSNE 165 Query: 178 GVIVKIVD 185 V++++ Sbjct: 166 HWDVEVLE 173 >1OFH-G nrPDB Length = 174 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 28/181 (15%), Positives = 65/181 (35%), Gaps = 13/181 (7%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQL-SPHTLMSFAGEAGDTVQFAEYI 60 I+ +R V++ V+ G +V+K + K R+L + L FAG D E Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 + ++++ + + + ++ R+ R + +++ D+K++ + I Sbjct: 61 ERKLEMHQGHLLKS-AVELAKDW------RTDRALRKLEAMLIVA--DEKESLI-ITGIG 110 Query: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 + E A G G Y S T ++++ ++ Sbjct: 111 DVVQPEEDQILAIGSGGNYALSAARALVEN--TELSAHEIVEKSLRIAGDICVFTNTNFT 168 Query: 181 V 181 + Sbjct: 169 I 169 >5LOX-A nrPDB Length = 242 Score = 46.5 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 28/201 (13%), Positives = 60/201 (29%), Gaps = 18/201 (8%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPH----TLMSFAGEAGDTVQFA 57 + + + D ++ AS GI + + K ++ AG + Sbjct: 1 TYCVAMHLADGLVFASDSRTNAGIDHIA-TFRKLFTFGTPGERLLVVQTAGNLATSQSVI 59 Query: 58 EYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRS-------RRPYQVNVLIGGYDKK 110 +Q I+ S ++ V + + + + ++GG Sbjct: 60 NLLQQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGG-QIA 118 Query: 111 KNKPELYQIDYLGTKVEL----PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQ 166 P LY I G ++ P+ G Y +LD + D E+ L + Sbjct: 119 GGPPALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCALVSFD 177 Query: 167 ELEKRMPMDFKGVIVKIVDKD 187 + + + + +D Sbjct: 178 STIRSNLSVGMPLDLLVYHRD 198 >5NYF-A nrPDB Length = 245 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 63/205 (30%), Gaps = 21/205 (10%) Query: 2 DIILGIRVQDSVILASSKAVTRG--ISVLKDSDDKTRQLSPHTL-MSFAGEAGDTVQFAE 58 + R++ ++ A+ G RQ + AG T Sbjct: 3 TYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVVS 62 Query: 59 YIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRR------------PYQVNVLIGG 106 I ++ + E L + + ++R R + N + GG Sbjct: 63 LINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFNTNFIFGG 122 Query: 107 YDKKKNKPELYQIDYLGTKVEL----PYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 K +P L+QI G +E P+ G Y +LD R DM E L+ Sbjct: 123 -QIKGERPRLFQIYPEGNFIEATDDTPFFQIGE-HKYGKPILDRVARSDMRLGEAAKLML 180 Query: 163 LCVQELEKRMPMDFKGVIVKIVDKD 187 L + + + I ++D Sbjct: 181 LSFDSTLRSNLSVGMPIDLVIYERD 205 >1M4Y-A nrPDB Length = 171 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 68/187 (36%), Gaps = 20/187 (10%) Query: 2 DIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSP-HTLMSFAGEAGDTVQFAEYI 60 IL +R ++ VT G +VLK + K R+L L FAG D + + Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 61 QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 +A +RE +A + + R + +L+ +K ++ I Sbjct: 61 EA-----KLREWGGNLTKAAVELAKDWRTDRVLRR--LEALLLVA------DKENIFIIS 107 Query: 121 YLGTKVE--LPYGAHGYSGFYTFSLLDHHYRP-DMTTEEGLDLLKLCVQELEKRMPMDFK 177 G ++ A G G Y + R D++ ++++ + + + Sbjct: 108 GNGEVIQPDDDAAAIGSGGPYALAAAKALLRNTDLS---AREIVEKAMTIAGEICIYTNQ 164 Query: 178 GVIVKIV 184 ++++ V Sbjct: 165 NIVIEEV 171 >2Z3B-A nrPDB Length = 180 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 65/187 (34%), Gaps = 23/187 (12%) Query: 2 DIILGIRVQDSVILASSKAVTRG-ISVLKDSDDKTRQL-SPHTLMSFAGEAGDTVQFAEY 59 I ++ + ++ VT G V+K + K R+L + L FAG D E Sbjct: 6 TTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTLFEK 65 Query: 60 IQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 +A ++ Y+ A ++ + + + + +++ N+ L + Sbjct: 66 FEAKLEEYNGNLKR-----AAVELAKEWRSDKVLRK--LEAMLIV------MNQDTLLLV 112 Query: 120 DYLGTKVELP--YGAHGYSGFYTFS---LLDHHYRPDMTTEEGLDLLKLCVQELEKRMPM 174 G +E A G G Y + L H M+ ++ + ++ + Sbjct: 113 SGTGEVIEPDDGILAIGSGGNYALAAGRALKKHAGESMS---ASEIARAALETAGEICVY 169 Query: 175 DFKGVIV 181 +I+ Sbjct: 170 TNDQIIL 176 >3TY6-A nrPDB Length = 183 Score = 35.0 bits (79), Expect = 0.024, Method: Composition-based stats. Identities = 29/184 (15%), Positives = 56/184 (30%), Gaps = 17/184 (9%) Query: 2 DIILGIRVQDSVILASSKAVTRGI-SVLKDSDDKTRQL-SPHTLMSFAGEAGDTVQFAEY 59 I + +A VT G V+K + K R+L L FAG D E Sbjct: 10 TTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEM 69 Query: 60 IQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQI 119 + ++ Y+ + + + + + R + +++ +K + + Sbjct: 70 FEGKLEEYNGNLQRA-AVEMAKQW------RGDKMLRQLEAMLIV------MDKTTMLLV 116 Query: 120 DYLGTKVELP--YGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 G +E A G G Y S + + K ++ Sbjct: 117 SGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEIAGDICVYTNH 176 Query: 178 GVIV 181 +IV Sbjct: 177 NIIV 180 >1RFZ-A nrPDB Length = 168 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 143 LLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQA 197 L Y PD+T EE ++ + + + E + + G+ + + +DG R + Q+ Sbjct: 36 YLQSKYHPDLTMEECIENVNRVISKREVQNAI-LTGIQLDKLAEDG-RLDEPLQS 88 >1WFZ-A nrPDB Length = 130 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 16/43 (37%) Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 Q+D G V+ + G S L + T EE L + Sbjct: 42 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 84 >5KZ5-a nrPDB Length = 118 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 16/43 (37%) Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 Q+D G V+ + G S L + T EE L + Sbjct: 29 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 71 >5WKP-D nrPDB Length = 150 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 16/43 (37%) Query: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 Q+D G V+ + G S L + T EE L + Sbjct: 53 QVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 95 >3MUN-A nrPDB Length = 693 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 37/106 (34%), Gaps = 7/106 (6%) Query: 48 GEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGY 107 G + D+ +Y++ L+++R V++ + S + L Sbjct: 587 GTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADHDDRVVPAHSFK--FAATLQA-- 642 Query: 108 DKKKNKPELYQIDY---LGTKVELPYGAHGYSGFYTFSLLDHHYRP 150 D P+L +I+ G + + Y F+L + YR Sbjct: 643 DNAGPHPQLIRIETNAGHGAGTPVAKLIEQSADIYAFTLYEMGYRE 688 >4ZYS-A nrPDB Length = 197 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 30/95 (31%), Gaps = 7/95 (7%) Query: 104 IGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKL 163 IGG K ++P + I P S L Y+ D++ +E L+ Sbjct: 87 IGGVTKTNSQPFIDYIH-------TPILEIKKGKEEPQSSLYQIYKEDISLKELDYRLRE 139 Query: 164 CVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ 198 + K + I KDG D + Sbjct: 140 RAIKQHGLYSNGLKQGQITITMKDGKSHTIDLSQK 174 >3ML0-B nrPDB Length = 551 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 29/83 (34%), Gaps = 9/83 (10%) Query: 98 YQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEG 157 Y + + G+D N P Y I GT E+ +GA Y+ + Sbjct: 33 YGIGLHGAGFDVVGNTPFAYPIVLFGTNSEIAWGATAGPQDVV-----DIYQEKLNPSRA 87 Query: 158 ----LDLLKLCVQELEKRMPMDF 176 + +++ ++R+ + Sbjct: 88 DQYWFNNAWRTMEQRKERIQVRG 110 >6FEC-5 nrPDB Length = 352 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 3/69 (4%) Query: 130 YGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGI 189 Y + Y F T +LLD + EE + L+ ++ + + + + K+++ + Sbjct: 120 YQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLME---V 176 Query: 190 RQVDDFQAQ 198 + DF + Sbjct: 177 CKEKDFSPE 185 >3J8B-H nrPDB Length = 343 Score = 27.3 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 3/69 (4%) Query: 130 YGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGI 189 Y + Y F T +LLD + EE + L+ ++ + + + + K+++ + Sbjct: 120 YQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLME---V 176 Query: 190 RQVDDFQAQ 198 + DF + Sbjct: 177 CKEKDFSPE 185 >6D97-A nrPDB Length = 547 Score = 27.3 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 46/118 (38%), Gaps = 6/118 (5%) Query: 48 GEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGY 107 G + + F A + + + +++ SS V ++LA ++ R V + G+ Sbjct: 242 GLPAEDMDFINSDGAVMNKLLLEANPKMTLFTGSSRVAEKLAADLKGR----VKLEDAGF 297 Query: 108 DKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLL--DHHYRPDMTTEEGLDLLKL 163 D K P++ ++DY+ + A S+L ++ E+ L + Sbjct: 298 DWKILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKKLSER 355 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.139 0.333 Lambda K H 0.267 0.0423 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,033,351 Number of Sequences: 36641 Number of extensions: 259494 Number of successful extensions: 1148 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 120 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 843 Number of HSP's gapped (non-prelim): 170 length of query: 198 length of database: 10,336,785 effective HSP length: 92 effective length of query: 106 effective length of database: 6,965,813 effective search space: 738376178 effective search space used: 738376178 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.5 bits)