BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P22033 (750 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3BIC-A nrPDB 1533 0.0 7REQ-A nrPDB 871 0.0 4R3U-A nrPDB 433 e-121 6REQ-B nrPDB 166 4e-41 2YXB-A nrPDB 108 1e-23 4R3U-C nrPDB 87 3e-17 1CB7-A nrPDB 37 0.047 3SE6-A nrPDB 35 0.084 4DBE-A nrPDB 32 0.81 3Q6J-A nrPDB 32 1.1 3TC8-A nrPDB 32 1.3 4WY0-A nrPDB 31 2.4 1BE1-A nrPDB 30 2.7 2ISS-A nrPDB 30 3.6 3K6J-A nrPDB 30 3.7 4JGI-A nrPDB 29 7.9 6DUY-A nrPDB 29 9.5 >3BIC-A nrPDB Length = 762 Score = 1533 bits (3968), Expect = 0.0, Method: Compositional matrix adjust. Identities = 737/740 (99%), Positives = 739/740 (99%) Query: 11 LSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK 70 +SPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK Sbjct: 1 MSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK 60 Query: 71 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG 130 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG Sbjct: 61 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG 120 Query: 131 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG 190 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG Sbjct: 121 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG 180 Query: 191 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA 250 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA Sbjct: 181 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA 240 Query: 251 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG 310 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG Sbjct: 241 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG 300 Query: 311 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT 370 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT Sbjct: 301 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT 360 Query: 371 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM 430 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM Sbjct: 361 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM 420 Query: 431 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN 490 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN Sbjct: 421 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN 480 Query: 491 KYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA 550 KYQLEKED VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA Sbjct: 481 KYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA 540 Query: 551 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER 610 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER Sbjct: 541 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER 600 Query: 611 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG 670 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG Sbjct: 601 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG 660 Query: 671 ISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK 730 +STLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK Sbjct: 661 VSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK 720 Query: 731 AAVQVLDDIEKCLEKKQQSV 750 AAVQVLDDIEKCLEKKQQSV Sbjct: 721 AAVQVLDDIEKCLEKKQQSV 740 >7REQ-A nrPDB Length = 727 Score = 871 bits (2250), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/711 (59%), Positives = 532/711 (74%), Gaps = 8/711 (1%) Query: 41 PEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSK--RDTMDLPEELPGVKPFTRGPYPT 98 P AA ++L K W T E I + L+++ MD + G+ PF GPY T Sbjct: 17 PADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYAT 76 Query: 99 MYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVG 158 MY FRPWTIRQYAGFST +ESN FY+ N+ AGQ+GLSVAFDL THRGYDSDNPRV GDVG Sbjct: 77 MYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVG 136 Query: 159 MAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQ 218 MAGVAID++ D + LF GIPL++MSVSMTMNGAV+P+LA ++VT EEQGV E+L GTIQ Sbjct: 137 MAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQ 196 Query: 219 NDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELA 278 NDILKEFMVRNTYI+PP+PSM+II++IF YT+ +MPK+NSISISGYHMQEAGA A +E+A Sbjct: 197 NDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMA 256 Query: 279 YTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQ 338 YTLADG++Y R G GL +D+FAPRLSFFWGIGMNF+ME+AK+RA R LWA L+ + F Sbjct: 257 YTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQ-FG 315 Query: 339 PKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPT 398 PKN KS+ LR H QTSGWSLT QD YNN+VRT IEAMAA G TQSLHTNS DEA+ LPT Sbjct: 316 PKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPT 375 Query: 399 VKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKA 458 SARIARNTQ+ +Q+ESG +V DPW GS +E LT D+ A I E+E++GGMAKA Sbjct: 376 DFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKA 435 Query: 459 VAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKL 518 + +GIPK+RIEE AAR QARIDSG + ++GVNKY+LE E ++VL +DN++V Q KL Sbjct: 436 IEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKL 495 Query: 519 KKIKSSRDQALAERCLAALTECAASGDG-----NILALAVDASRARCTVGEITDALKKVF 573 K+++ RD + L +T A + D N+L L +DA RA TVGE++DAL+KVF Sbjct: 496 VKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVF 555 Query: 574 GEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKV 633 G + A R +SG Y +E + E+ A + V +F + EGRRPR+L+AKMGQDGHDRG KV Sbjct: 556 GRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKV 615 Query: 634 IATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLG 693 IAT +ADLGFDVD+GPLFQTP E A+QAV+ADVH VG+S+LA GH TLVP L KEL+ LG Sbjct: 616 IATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLG 675 Query: 694 RPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLE 744 RPDIL+ GGVIP QD++ L + G ++ PGT IP++A+ ++ + L+ Sbjct: 676 RPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLD 726 >4R3U-A nrPDB Length = 584 Score = 433 bits (1113), Expect = e-121, Method: Compositional matrix adjust. Identities = 227/560 (40%), Positives = 346/560 (61%), Gaps = 6/560 (1%) Query: 23 SGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPE-DLIWHTPEGISIKPLYSKRDTMDL 81 SG ++ ++ Q Q +W A K PE +HT ++ Y+ D D Sbjct: 10 SGMTWLEPQIKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFPVQRTYTAADIADT 69 Query: 82 PEE---LPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAF 138 P E LPG PFTRGPYPTMY R WT+RQ AGF T E++NK +K I GQ G+S F Sbjct: 70 PLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGISTDF 129 Query: 139 DLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLAN 198 D+ T GYDSD+P G+VG GVAIDT+ D + L I LEK+SVS T+N + +LA Sbjct: 130 DMPTLMGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKISVSFTINPSAWILLAM 189 Query: 199 FIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNS 258 ++ GE++G KL+GT+Q DILKE+M + YI+P PS++I+ DI Y+AK++ ++N Sbjct: 190 YVALGEKRGYDLNKLSGTVQADILKEYMAQKEYIYPIAPSVRIVRDIITYSAKNLKRYNP 249 Query: 259 ISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYME 318 I+ISGYH+ EAG+ + E A+TLA+ + Y + G+ +DEFAPRL+FF+ +F+ E Sbjct: 250 INISGYHISEAGSSPLQEAAFTLANLITYVNEVTKTGMHVDEFAPRLAFFFVSQGDFFEE 309 Query: 319 IAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAV 378 +AK RA RR +A ++++ F +N +S+ LR HCQT+ +LT+ N+VRT+++A++AV Sbjct: 310 VAKFRALRRCYAKIMKERFGARNPESMRLRFHCQTAAATLTKPQYMVNVVRTSLQALSAV 369 Query: 379 FGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDV 438 GG QSLHTN +DEA +PT + ++A TQ II EESG+ V DP GGSY +E LT + Sbjct: 370 LGGAQSLHTNGYDEAFAIPTEDAMKMALRTQQIIAEESGVADVIDPLGGSYYVEALTTEY 429 Query: 439 YDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKED 498 +++ E+E+ GG K + +G + +I + A R SG + ++GVN++ +ED Sbjct: 430 EKKIFEILEEVEKRGGTIKLIEQGWFQKQIADFAYETALRKQSGQKPVIGVNRFVENEED 489 Query: 499 A-VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASR 557 +E+ DNT+ RQI + +++++ RD+A + L L A N++ L ++ + Sbjct: 490 VKIEIHPYDNTTA-ERQISRTRRVRAERDEAKVQAMLDQLVAVAKDESQNLMPLTIELVK 548 Query: 558 ARCTVGEITDALKKVFGEHK 577 A T+G+I + LK ++G ++ Sbjct: 549 AGATMGDIVEKLKGIWGTYR 568 >6REQ-B nrPDB Length = 637 Score = 166 bits (420), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 142/441 (32%), Positives = 211/441 (47%), Gaps = 39/441 (8%) Query: 59 LIWHTPEGISIKPLYSKRDTMDLPEEL--PGVKPFTRGPYPTMYTFRPWTIRQYAGFSTV 116 L HT +GI I P+Y +D P++L PGV PFTRG W +R Sbjct: 61 LTVHTVDGIDIVPMYRPKDA---PKKLGYPGVAPFTRGTTVRNGDMDAWDVRALHE---- 113 Query: 117 EESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDG 176 + KF + KA +GL RG S RV D +A +D V +L Sbjct: 114 DPDEKFTR---KAILEGL--------ERGVTSLLLRVDPD-AIAPEHLDEVLSDVLL--- 158 Query: 177 IPLEKMSV-SMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPP 235 + K+ V S GA L + E P + L + D + ++ T Sbjct: 159 -EMTKVEVFSRYDQGAAAEALVSVY---ERSDKPAKDLALNLGLDPIGFAALQGT----- 209 Query: 236 EPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAG 295 EP + ++ D AK P +++I AGA + ELA+ LA G EY R ++ G Sbjct: 210 EPDLTVLGDWVRRLAKFSPDSRAVTIDANIYHNAGAGDVAELAWALATGAEYVRALVEQG 269 Query: 296 LTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSG 355 T E ++F + ++ IA++RA R WA + E ++ + R + TS Sbjct: 270 FTATEAFDTINFRVTATHDQFLTIARLRALREAWARIGEVFGVDEDKRGA--RQNAITSW 327 Query: 356 WSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVK-SARIARNTQIIIQE 414 LT +DPY NI+R +I +A GG +S+ T F +ALGLP RIARNT I++ E Sbjct: 328 RELTREDPYVNILRGSIATFSASVGGAESITTLPFTQALGLPEDDFPLRIARNTGIVLAE 387 Query: 415 ESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAV-AEGIPKLRIEECAA 473 E I +V DP GGSY +E LT + DAA K E+E++GGM+KAV E + K+ ++ C A Sbjct: 388 EVNIGRVNDPAGGSYYVESLTRSLADAAWKEFQEVEKLGGMSKAVMTEHVTKV-LDACNA 446 Query: 474 RRQARIDSGSEVIVGVNKYQL 494 R R+ + + I V+++ + Sbjct: 447 ERAKRLANRKQPITAVSEFPM 467 >2YXB-A nrPDB Length = 161 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 59/135 (43%), Positives = 81/135 (60%), Gaps = 4/135 (2%) Query: 613 RRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGIS 672 RR ++LVAKMG DGHDRGAKV+A D GF+V L QTP +VA AV DV +G+S Sbjct: 17 RRYKVLVAKMGLDGHDRGAKVVARALRDAGFEVVYTGLRQTPEQVAMAAVQEDVDVIGVS 76 Query: 673 TLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAA 732 L H L+ L+ +L LG DI V+ GG IP D E L +G+ +F PGT + Sbjct: 77 ILNGAHLHLMKRLMAKLRELGADDIPVVLGGTIPIPDLEPLRSLGIREIFLPGTSLG--- 133 Query: 733 VQVLDDIEKCLEKKQ 747 ++++ + K E+K+ Sbjct: 134 -EIIEKVRKLAEEKR 147 >4R3U-C nrPDB Length = 158 Score = 87.0 bits (214), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 44/107 (41%), Positives = 65/107 (60%) Query: 616 RLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLA 675 R+L+AK+G DGHDRG KV+A D G DV L +TP EV A+ DV +G+S L+ Sbjct: 18 RVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAIQEDVDVLGVSLLS 77 Query: 676 AGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVF 722 T+ P++ K L+ G D++V+ GGV+P +D + ++GV V Sbjct: 78 GVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAAIRKLGVREVL 124 >1CB7-A nrPDB Length = 137 Score = 36.6 bits (83), Expect = 0.047, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 10/122 (8%) Query: 613 RRPRLLVAKMGQDGHDRGAKVIATGFADLGFD-VDIGPLFQTPREV-AQQAVDADVHAVG 670 + +++ +G D H G K++ F + GF+ V+IG L +P+E+ + A++ A+ Sbjct: 2 EKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVL--SPQELFIKAAIETKADAIL 59 Query: 671 ISTLAAGHKTLVPELIKELNSLGRPDILVMCGG--VIPPQ---DYEFLF-EVGVSNVFGP 724 +S+L + L ++ + G IL+ GG V+ Q D E F ++G V+ P Sbjct: 60 VSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAP 119 Query: 725 GT 726 GT Sbjct: 120 GT 121 >3SE6-A nrPDB Length = 967 Score = 35.4 bits (80), Expect = 0.084, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 35/80 (43%), Gaps = 18/80 (22%) Query: 19 VKESSGS-RLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKP------ 71 VK+ S RL Q+R L PEW AL ++ L WH P S Sbjct: 552 VKQDGCSLRLQQERFLQGVFQEDPEWRALQERYL---------WHIPLTYSTSSSNVIHR 602 Query: 72 --LYSKRDTMDLPEELPGVK 89 L SK DT+DLPE+ VK Sbjct: 603 HILKSKTDTLDLPEKTSWVK 622 >4DBE-A nrPDB Length = 222 Score = 32.3 bits (72), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 335 KMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSF 390 K + NSK+L L A GWS D N++R I V GGT+ H + Sbjct: 98 KRYLDANSKNLYLVAVMSHEGWSTLFADYIKNVIRE-ISPKGIVVGGTKLDHITQY 152 >3Q6J-A nrPDB Length = 523 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Query: 246 FEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRL 305 F HM F I I + GA + Y D +Y ++ GLT+DE Sbjct: 442 FGKGTAHMSGFQKIVIDAKTRKVLGAHHV---GYGAKDAFQYLNVLIKQGLTVDELGDMD 498 Query: 306 SFFWGIGMNFYMEIAKMRAGRR 327 F + +++++++RAG + Sbjct: 499 ELF--LNPTHFIQLSRLRAGSK 518 >3TC8-A nrPDB Length = 309 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 311 IGMNFYMEIAKMRA--GRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDP 363 G Y + A + A G +L A I F P+NSK +LL AH + +S + DP Sbjct: 61 FGAKVYQQEAILTAYDGTKLEARNIIGSFDPENSKRVLLFAHWDSRPYSDHDPDP 115 >4WY0-A nrPDB Length = 305 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 684 ELIKELNSLGR-PDILVMCGGVIPPQDYEFLFEVGVSNVF 722 E+++E+ LGR P + GGV P D + +G VF Sbjct: 204 EVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVF 243 >1BE1-A nrPDB Length = 137 Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 8/121 (6%) Query: 613 RRPRLLVAKMGQDGHDRGAKVIATGFADLGFD-VDIGPLFQTPREVAQQAVDADVHAVGI 671 + +++ +G D H G K++ F + GF+ V+IG L + + A++ + + Sbjct: 2 EKKTIVLGVIGSDCHAVGNKILDHSFTNAGFNVVNIGVL-SSQEDFINAAIETKADLICV 60 Query: 672 STLAAGHKTLVPELIKELNSLGRPDILVMCGG--VIPPQ---DYEFLFE-VGVSNVFGPG 725 S+L + L ++ + G I + GG V+ Q D E F+ +G V+ PG Sbjct: 61 SSLYGQGEIDCKGLREKCDEAGLKGIKLFVGGNIVVGKQNWPDVEQRFKAMGFDRVYPPG 120 Query: 726 T 726 T Sbjct: 121 T 121 >2ISS-A nrPDB Length = 313 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 684 ELIKELNSLGR-PDILVMCGGVIPPQDYEFLFEVGVSNVF 722 EL++E+ LGR P + GGV P D + +G VF Sbjct: 215 ELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVF 254 >3K6J-A nrPDB Length = 460 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 337 FQPKNSKSLLLRAHCQTSGWSL-TEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALG 395 FQ +S L+ AH WSL ++ + N + ++A + GGT + G Sbjct: 18 FQGSEVRSYLMEAHSLAGQWSLPNDRGDHTNSEAYDVNSVAIIGGGTMG---KAMAICFG 74 Query: 396 LPTVKSARIARNTQIIIQE 414 L +++ + RN Q QE Sbjct: 75 LAGIETFLVVRNEQRCKQE 93 >4JGI-A nrPDB Length = 211 Score = 28.9 bits (63), Expect = 7.9, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 15/100 (15%) Query: 613 RRPRLLVAKMGQDGHDRGAKVI-----ATGFA--DLGFDVDIGPLFQTPREVAQQAVDAD 665 +R ++++A + D HD G + A+GF DLG DV + + +EV + Sbjct: 88 KRAKIVLATVEGDLHDIGKNIFRTMAEASGFEVFDLGIDVPVKIIVDKVKEVNPEI---- 143 Query: 666 VHAVGISTLAAGHKTLVPELIKELNSLG-RPDILVMCGGV 704 V G+ TLA + E + L + G R D+ V+ GGV Sbjct: 144 VGLSGVLTLALDS---MRETVDALKAEGLRNDLKVIIGGV 180 >6DUY-A nrPDB Length = 257 Score = 28.9 bits (63), Expect = 9.5, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 24/93 (25%) Query: 396 LPTVKSARIARNTQIIIQEESGIPKVADPWGGS-------------YMMECL-------- 434 LP + A+IA +I QE+S + W S MME Sbjct: 27 LPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGP 86 Query: 435 ---TNDVYDAALKLINEIEEMGGMAKAVAEGIP 464 T+DV +AA K+ M +A+AVA+ P Sbjct: 87 LKNTSDVINAAKKIAEAGSRMDKLARAVADQCP 119 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3BIC-A nrPDB 1265 0.0 7REQ-A nrPDB 1073 0.0 4R3U-A nrPDB 795 0.0 6REQ-B nrPDB 502 e-142 2YXB-A nrPDB 194 2e-49 4R3U-C nrPDB 167 2e-41 Sequences not found previously or not previously below threshold: 1BE1-A nrPDB 59 7e-09 1CB7-A nrPDB 58 1e-08 3Q6J-A nrPDB 42 9e-04 1XRS-B nrPDB 39 0.006 3O8O-B nrPDB 38 0.014 4JGI-A nrPDB 37 0.022 1Y80-A nrPDB 37 0.024 1YTE-A nrPDB 36 0.077 2I2X-B nrPDB 34 0.18 3OTH-A nrPDB 34 0.28 4P0F-A nrPDB 33 0.49 5J40-A nrPDB 32 0.91 5CSA-A nrPDB 32 1.0 5W3M-A nrPDB 32 1.3 3U7J-A nrPDB 30 2.8 3MVK-A nrPDB 30 3.3 3OPY-B nrPDB 30 3.8 6GYB-c nrPDB 30 4.1 3O8O-A nrPDB 30 5.1 >3BIC-A nrPDB Length = 762 Score = 1265 bits (3274), Expect = 0.0, Method: Composition-based stats. Identities = 737/740 (99%), Positives = 739/740 (99%) Query: 11 LSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK 70 +SPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK Sbjct: 1 MSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIK 60 Query: 71 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG 130 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG Sbjct: 61 PLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAG 120 Query: 131 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG 190 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG Sbjct: 121 QQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNG 180 Query: 191 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA 250 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA Sbjct: 181 AVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTA 240 Query: 251 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG 310 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG Sbjct: 241 KHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWG 300 Query: 311 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT 370 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT Sbjct: 301 IGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRT 360 Query: 371 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM 430 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM Sbjct: 361 AIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYM 420 Query: 431 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN 490 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN Sbjct: 421 MECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVN 480 Query: 491 KYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA 550 KYQLEKED VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA Sbjct: 481 KYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILA 540 Query: 551 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER 610 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER Sbjct: 541 LAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMER 600 Query: 611 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG 670 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG Sbjct: 601 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVG 660 Query: 671 ISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK 730 +STLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK Sbjct: 661 VSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPK 720 Query: 731 AAVQVLDDIEKCLEKKQQSV 750 AAVQVLDDIEKCLEKKQQSV Sbjct: 721 AAVQVLDDIEKCLEKKQQSV 740 >7REQ-A nrPDB Length = 727 Score = 1073 bits (2776), Expect = 0.0, Method: Composition-based stats. Identities = 426/711 (59%), Positives = 532/711 (74%), Gaps = 8/711 (1%) Query: 41 PEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSK--RDTMDLPEELPGVKPFTRGPYPT 98 P AA ++L K W T E I + L+++ MD + G+ PF GPY T Sbjct: 17 PADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYAT 76 Query: 99 MYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVG 158 MY FRPWTIRQYAGFST +ESN FY+ N+ AGQ+GLSVAFDL THRGYDSDNPRV GDVG Sbjct: 77 MYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVG 136 Query: 159 MAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQ 218 MAGVAID++ D + LF GIPL++MSVSMTMNGAV+P+LA ++VT EEQGV E+L GTIQ Sbjct: 137 MAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQ 196 Query: 219 NDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELA 278 NDILKEFMVRNTYI+PP+PSM+II++IF YT+ +MPK+NSISISGYHMQEAGA A +E+A Sbjct: 197 NDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMA 256 Query: 279 YTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQ 338 YTLADG++Y R G GL +D+FAPRLSFFWGIGMNF+ME+AK+RA R LWA L+ + F Sbjct: 257 YTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQ-FG 315 Query: 339 PKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPT 398 PKN KS+ LR H QTSGWSLT QD YNN+VRT IEAMAA G TQSLHTNS DEA+ LPT Sbjct: 316 PKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPT 375 Query: 399 VKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKA 458 SARIARNTQ+ +Q+ESG +V DPW GS +E LT D+ A I E+E++GGMAKA Sbjct: 376 DFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKA 435 Query: 459 VAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKL 518 + +GIPK+RIEE AAR QARIDSG + ++GVNKY+LE E ++VL +DN++V Q KL Sbjct: 436 IEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKL 495 Query: 519 KKIKSSRDQALAERCLAALTECAASGDG-----NILALAVDASRARCTVGEITDALKKVF 573 K+++ RD + L +T A + D N+L L +DA RA TVGE++DAL+KVF Sbjct: 496 VKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVF 555 Query: 574 GEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKV 633 G + A R +SG Y +E + E+ A + V +F + EGRRPR+L+AKMGQDGHDRG KV Sbjct: 556 GRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKV 615 Query: 634 IATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLG 693 IAT +ADLGFDVD+GPLFQTP E A+QAV+ADVH VG+S+LA GH TLVP L KEL+ LG Sbjct: 616 IATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLG 675 Query: 694 RPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLE 744 RPDIL+ GGVIP QD++ L + G ++ PGT IP++A+ ++ + L+ Sbjct: 676 RPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLD 726 >4R3U-A nrPDB Length = 584 Score = 795 bits (2053), Expect = 0.0, Method: Composition-based stats. Identities = 227/560 (40%), Positives = 346/560 (61%), Gaps = 6/560 (1%) Query: 23 SGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPE-DLIWHTPEGISIKPLYSKRDTMDL 81 SG ++ ++ Q Q +W A K PE +HT ++ Y+ D D Sbjct: 10 SGMTWLEPQIKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFPVQRTYTAADIADT 69 Query: 82 PEE---LPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAF 138 P E LPG PFTRGPYPTMY R WT+RQ AGF T E++NK +K I GQ G+S F Sbjct: 70 PLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGISTDF 129 Query: 139 DLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLAN 198 D+ T GYDSD+P G+VG GVAIDT+ D + L I LEK+SVS T+N + +LA Sbjct: 130 DMPTLMGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKISVSFTINPSAWILLAM 189 Query: 199 FIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNS 258 ++ GE++G KL+GT+Q DILKE+M + YI+P PS++I+ DI Y+AK++ ++N Sbjct: 190 YVALGEKRGYDLNKLSGTVQADILKEYMAQKEYIYPIAPSVRIVRDIITYSAKNLKRYNP 249 Query: 259 ISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYME 318 I+ISGYH+ EAG+ + E A+TLA+ + Y + G+ +DEFAPRL+FF+ +F+ E Sbjct: 250 INISGYHISEAGSSPLQEAAFTLANLITYVNEVTKTGMHVDEFAPRLAFFFVSQGDFFEE 309 Query: 319 IAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAV 378 +AK RA RR +A ++++ F +N +S+ LR HCQT+ +LT+ N+VRT+++A++AV Sbjct: 310 VAKFRALRRCYAKIMKERFGARNPESMRLRFHCQTAAATLTKPQYMVNVVRTSLQALSAV 369 Query: 379 FGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDV 438 GG QSLHTN +DEA +PT + ++A TQ II EESG+ V DP GGSY +E LT + Sbjct: 370 LGGAQSLHTNGYDEAFAIPTEDAMKMALRTQQIIAEESGVADVIDPLGGSYYVEALTTEY 429 Query: 439 YDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKED 498 +++ E+E+ GG K + +G + +I + A R SG + ++GVN++ +ED Sbjct: 430 EKKIFEILEEVEKRGGTIKLIEQGWFQKQIADFAYETALRKQSGQKPVIGVNRFVENEED 489 Query: 499 A-VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASR 557 +E+ DNT+ RQI + +++++ RD+A + L L A N++ L ++ + Sbjct: 490 VKIEIHPYDNTTA-ERQISRTRRVRAERDEAKVQAMLDQLVAVAKDESQNLMPLTIELVK 548 Query: 558 ARCTVGEITDALKKVFGEHK 577 A T+G+I + LK ++G ++ Sbjct: 549 AGATMGDIVEKLKGIWGTYR 568 >6REQ-B nrPDB Length = 637 Score = 502 bits (1292), Expect = e-142, Method: Composition-based stats. Identities = 151/521 (28%), Positives = 232/521 (44%), Gaps = 50/521 (9%) Query: 29 QQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEEL--P 86 ++ + P L + + L HT +GI I P+Y +D P++L P Sbjct: 35 EREVEKVLNRGRPPEKQLTFAECLKR----LTVHTVDGIDIVPMYRPKDA---PKKLGYP 87 Query: 87 GVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGY 146 GV PFTRG W +R + KF + KA +GL RG Sbjct: 88 GVAPFTRGTTVRNGDMDAWDVRALHE----DPDEKFTR---KAILEGL--------ERGV 132 Query: 147 DSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSV-SMTMNGAVIPVLANFIVTGEE 205 S RV D +A +D V +L + K+ V S GA L + E Sbjct: 133 TSLLLRVDPD-AIAPEHLDEVLSDVLL----EMTKVEVFSRYDQGAAAEALVSVY---ER 184 Query: 206 QGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYH 265 P + L + D + ++ T EP + ++ D AK P +++I Sbjct: 185 SDKPAKDLALNLGLDPIGFAALQGT-----EPDLTVLGDWVRRLAKFSPDSRAVTIDANI 239 Query: 266 MQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAG 325 AGA + ELA+ LA G EY R ++ G T E ++F + ++ IA++RA Sbjct: 240 YHNAGAGDVAELAWALATGAEYVRALVEQGFTATEAFDTINFRVTATHDQFLTIARLRAL 299 Query: 326 RRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSL 385 R WA + E ++ + R + TS LT +DPY NI+R +I +A GG +S+ Sbjct: 300 REAWARIGEVFGVDEDKRGA--RQNAITSWRELTREDPYVNILRGSIATFSASVGGAESI 357 Query: 386 HTNSFDEALGLPTVK-SARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALK 444 T F +ALGLP RIARNT I++ EE I +V DP GGSY +E LT + DAA K Sbjct: 358 TTLPFTQALGLPEDDFPLRIARNTGIVLAEEVNIGRVNDPAGGSYYVESLTRSLADAAWK 417 Query: 445 LINEIEEMGGMAKAV-AEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVL 503 E+E++GGM+KAV E + K+ ++ C A R R+ + + I V+++ + ++E Sbjct: 418 EFQEVEKLGGMSKAVMTEHVTKV-LDACNAERAKRLANRKQPITAVSEFPMIGARSIETK 476 Query: 504 AIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASG 544 R K + RD + E+ + T + Sbjct: 477 PFPAAPAR-------KGLAWHRDSEVFEQLMDRSTSVSERP 510 >2YXB-A nrPDB Length = 161 Score = 194 bits (492), Expect = 2e-49, Method: Composition-based stats. Identities = 62/151 (41%), Positives = 87/151 (57%), Gaps = 7/151 (4%) Query: 597 ITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPRE 656 + S +RV + RR ++LVAKMG DGHDRGAKV+A D GF+V L QTP + Sbjct: 4 LQSTRERV---LGTPRRRYKVLVAKMGLDGHDRGAKVVARALRDAGFEVVYTGLRQTPEQ 60 Query: 657 VAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEV 716 VA AV DV +G+S L H L+ L+ +L LG DI V+ GG IP D E L + Sbjct: 61 VAMAAVQEDVDVIGVSILNGAHLHLMKRLMAKLRELGADDIPVVLGGTIPIPDLEPLRSL 120 Query: 717 GVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQ 747 G+ +F PGT + ++++ + K E+K+ Sbjct: 121 GIREIFLPGTSLG----EIIEKVRKLAEEKR 147 >4R3U-C nrPDB Length = 158 Score = 167 bits (423), Expect = 2e-41, Method: Composition-based stats. Identities = 49/131 (37%), Positives = 74/131 (56%), Gaps = 4/131 (3%) Query: 616 RLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLA 675 R+L+AK+G DGHDRG KV+A D G DV L +TP EV A+ DV +G+S L+ Sbjct: 18 RVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAIQEDVDVLGVSLLS 77 Query: 676 AGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQV 735 T+ P++ K L+ G D++V+ GGV+P +D + ++GV V T P A + Sbjct: 78 GVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAAIRKLGVREVLLQDT--PPQA--I 133 Query: 736 LDDIEKCLEKK 746 +D I + + Sbjct: 134 IDSIRSLVAAR 144 >1BE1-A nrPDB Length = 137 Score = 59.0 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 56/129 (43%), Gaps = 7/129 (5%) Query: 617 LLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAA 676 +++ +G D H G K++ F + GF+V + + + A++ + +S+L Sbjct: 6 IVLGVIGSDCHAVGNKILDHSFTNAGFNVVNIGVLSSQEDFINAAIETKADLICVSSLYG 65 Query: 677 GHKTLVPELIKELNSLGRPDILVMCGGVIPP-----QDYEFLFE-VGVSNVFGPGTRIPK 730 + L ++ + G I + GG I D E F+ +G V+ PGT P+ Sbjct: 66 QGEIDCKGLREKCDEAGLKGIKLFVGGNIVVGKQNWPDVEQRFKAMGFDRVYPPGTS-PE 124 Query: 731 AAVQVLDDI 739 + + ++ Sbjct: 125 TTIADMKEV 133 >1CB7-A nrPDB Length = 137 Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 7/128 (5%) Query: 617 LLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAA 676 +++ +G D H G K++ F + GF+V + + A++ A+ +S+L Sbjct: 6 IVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQELFIKAAIETKADAILVSSLYG 65 Query: 677 GHKTLVPELIKELNSLGRPDILVMCGGVIPP-----QDYEFLFEV-GVSNVFGPGTRIPK 730 + L ++ + G IL+ GG I D E F+ G V+ PGT P+ Sbjct: 66 QGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTP-PE 124 Query: 731 AAVQVLDD 738 + L Sbjct: 125 VGIADLKK 132 >3Q6J-A nrPDB Length = 523 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 49/131 (37%), Gaps = 9/131 (6%) Query: 197 ANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKF 256 +F+ GEE+ TI+ E + P ++ F HM F Sbjct: 397 VSFLGMGEEEARAAGHEIVTIKMPPDTE---NGLNVALPASDRTMLYA-FGKGTAHMSGF 452 Query: 257 NSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFY 316 I I + GA + Y D +Y ++ GLT+DE F + Sbjct: 453 QKIVIDAKTRKVLGAHHV---GYGAKDAFQYLNVLIKQGLTVDELGDMDELFLNPTH--F 507 Query: 317 MEIAKMRAGRR 327 ++++++RAG + Sbjct: 508 IQLSRLRAGSK 518 >1XRS-B nrPDB Length = 262 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 15/143 (10%) Query: 596 EITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLG---------FDVD 646 EI S + E GR+ ++ A G D H G I G D Sbjct: 102 EILSMEETDEYIKENIGRKIVVVGASTGTDAHTVGIDAIMNMKGYAGHYGLERYEMIDAY 161 Query: 647 IGPLFQTPREVAQQAVDADVHAVGIS---TLAAGHKTLVPELIKELNSLG-RPDILVMCG 702 + ++AV+ + + +S T H + LI+ L + G R +++CG Sbjct: 162 NLGSQVANEDFIKKAVELEADVLLVSQTVTQKNVHIQNMTHLIELLEAEGLRDRFVLLCG 221 Query: 703 GVIPPQDYEFLFEVGVSNVFGPG 725 G P + E E+G FGPG Sbjct: 222 G--PRINNEIAKELGYDAGFGPG 242 >3O8O-B nrPDB Length = 766 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 63/174 (36%), Gaps = 14/174 (8%) Query: 405 ARNTQIIIQEESGIPKVADPWGGS----YMMECLTNDVYDAALKLINEIEEMGGMAKAVA 460 + T I++ E I P S +++ L D L + GG A A Sbjct: 244 GKRTTIVVVAEGAIAADLTPISPSDVHKVLVDRLGLDTRITTLGHVQ----RGGTAVAYD 299 Query: 461 EGIPKLR-IEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLK 519 + L+ +E A ++ D+ S ++ VN+ ++ ++ +E + + Q + K Sbjct: 300 RILATLQGLEAVNAVLESTPDTPS-PLIAVNENKIVRKPLMESVKLTKAVAEAIQAKDFK 358 Query: 520 KIKSSRDQALAERCLAALTECAASGDGNILA----LAVDASRARCTVGEITDAL 569 + S RD E + +A + L L + G I A+ Sbjct: 359 RAMSLRDTEFIEHLNNFMAINSADHNEPKLPKDKRLKIAIVNVGAPAGGINSAV 412 >4JGI-A nrPDB Length = 211 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 70/184 (38%), Gaps = 17/184 (9%) Query: 523 SSRDQALAERCLAALTECA-ASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDR 581 S D+ + + A A ++ + VGE D+ GE+ D Sbjct: 12 SDLDEGAINEVVDKVMAKADADAAQELIK---AFQQGMTKVGERFDS-----GEYFIGDL 63 Query: 582 MVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADL 641 + +G Q + + + + K R ++++A + D HD G + T Sbjct: 64 IFAGEILQAAMDKLKPALSGDALEK-------RAKIVLATVEGDLHDIGKNIFRTMAEAS 116 Query: 642 GFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLG-RPDILVM 700 GF+V + + + + + + VG+S + + E + L + G R D+ V+ Sbjct: 117 GFEVFDLGIDVPVKIIVDKVKEVNPEIVGLSGVLTLALDSMRETVDALKAEGLRNDLKVI 176 Query: 701 CGGV 704 GGV Sbjct: 177 IGGV 180 >1Y80-A nrPDB Length = 210 Score = 37.4 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 38/97 (39%), Gaps = 1/97 (1%) Query: 616 RLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLA 675 ++++ + D HD G ++A GF V + P + + VG+S L Sbjct: 90 KIVLGTVKGDLHDIGKNLVAMMLESGGFTVYNLGVDIEPGKFVEAVKKYQPDIVGMSALL 149 Query: 676 AGHKTLVPELIKELNSLG-RPDILVMCGGVIPPQDYE 711 + I L + G R + V+ GG QD+ Sbjct: 150 TTTMMNMKSTIDALIAAGLRDRVKVIVGGAPLSQDFA 186 >1YTE-A nrPDB Length = 398 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 672 STLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKA 731 S+ + L+ E+ EL GR DI +M G + + L E G FG GT I A Sbjct: 246 SSRRGNFEALIREVRWELALRGRSDIKIMVSGGLDENTVKKLREAGA-EAFGVGTSISSA 304 >2I2X-B nrPDB Length = 258 Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 34/96 (35%), Gaps = 5/96 (5%) Query: 625 DGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDAD--VHAVGISTLAAGHKTLV 682 D HD G ++ G++V P E AV + + G + + Sbjct: 134 DVHDIGKNIVTALLRANGYNVVDLG-RDVPAEEVLAAVQKEKPIMLTGTALMTTT-MYAF 191 Query: 683 PELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGV 718 E+ L G I CGG QD+ F +GV Sbjct: 192 KEVNDMLLENGI-KIPFACGGGAVNQDFVSQFALGV 226 >3OTH-A nrPDB Length = 412 Score = 33.9 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 17/116 (14%) Query: 611 EGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDI-------GPLFQ---TPREVAQQ 660 EGR R+L A +G GH +AT G +V G L + P Sbjct: 17 EGRHMRVLFASLGTHGHTYPLLPLATAARAAGHEVTFATGEGFAGTLRKLGFEPVATGMP 76 Query: 661 AVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEV 716 D + A+ I + L PE + EL ++ G VIP + ++ L V Sbjct: 77 VFDGFLAALRIRFDTDSPEGLTPEQLSELPQ-------IVFGRVIPQRVFDELQPV 125 >4P0F-A nrPDB Length = 393 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Query: 346 LLRAHCQTSGWSLTEQDPYNNIVRT--AIEAMAAVFG-GTQSLHTNSFDEALGLPTVKSA 402 L L+ Q P NIV + +I+ AA+ G ++ D+ LGL + Sbjct: 13 RLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPE 72 Query: 403 RIARNTQIIIQ--EESGIPKVAD 423 +IA + ++ ++S I ++A+ Sbjct: 73 QIAHSFHQVLAAYQDSQILRIAN 95 >5J40-A nrPDB Length = 372 Score = 32.0 bits (71), Expect = 0.91, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 42/106 (39%), Gaps = 12/106 (11%) Query: 215 GTIQNDILKEFMVRNTYIFPPEPSM-KIIADIFEYTAKHMPKFNSISISGYHMQEAGADA 273 G N +L+++M +I P M +I + + ++PK G ++G Sbjct: 122 GAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPI--DSGKTT 179 Query: 274 ILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEI 319 + L G L ++ RL+F G+G++ +M + Sbjct: 180 LAAALLDLCGG---------KSLNVNMPLERLNFELGVGIDQFMVV 216 >5CSA-A nrPDB Length = 932 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 8/63 (12%) Query: 611 EGRRPRLLVAKMGQDGHD---RGAK--VIATGFADLGFDVDIGPLFQT---PREVAQQAV 662 EG+R + VAK G D + G+K +I +D G + IG T EVA + Sbjct: 58 EGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRL 117 Query: 663 DAD 665 D Sbjct: 118 SVD 120 >5W3M-A nrPDB Length = 289 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 54/137 (39%), Gaps = 7/137 (5%) Query: 226 MVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSI-SISGYHMQEAGADAILELAYTLADG 284 +V+ Y+ P P+ K D +A + F + S + + G + Y DG Sbjct: 147 VVQAMYVPPGAPNPKEWDDYTWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFY---DG 203 Query: 285 LEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKS 344 + Q G+T+ ++F + + + K+R R A +E + P+ ++ Sbjct: 204 YSHDDAETQYGITVLNHMGSMAFRIVNEHDEHKTLVKIRVYHR--AKHVEA-WIPRAPRA 260 Query: 345 LLLRAHCQTSGWSLTEQ 361 L + +T+ TE Sbjct: 261 LPYTSIGRTNYPKNTEP 277 >3U7J-A nrPDB Length = 239 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 4/67 (5%) Query: 447 NEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAID 506 +EI+E G M K + + +I A I S+ + + ++ L VEV+ + Sbjct: 96 DEIDESGAMIKGGGGALTREKIVASVAETFVCIADASKRVAMLGQFPL----PVEVVPMA 151 Query: 507 NTSVRNR 513 T++ R Sbjct: 152 RTAIGRR 158 >3MVK-A nrPDB Length = 148 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 673 TLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQ 708 L K + PEL+K L +G D LV+ G P + Sbjct: 1 MLKGIPKIIPPELLKVLCEMGHGDQLVIADGNFPAE 36 >3OPY-B nrPDB Length = 941 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 64/174 (36%), Gaps = 9/174 (5%) Query: 402 ARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVY-DAALKLINEIEEMGGMAKAVA 460 AR R T I+I E I P + + L N + D + + ++ GG A A Sbjct: 420 ARGKRKT-IVIVAEGAISNDLSPISCDQVKDVLVNRLGLDTRVTTLGHVQ-RGGTAVAFD 477 Query: 461 EGIPKLR-IEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLK 519 L+ +E A + D+ S ++ + + Q+ + V+ + + ++ + K Sbjct: 478 RIYATLQGVEAVNAVLECDADTPS-PMIAIKEDQITRVPLVDAVELTQQVAKSIESRNFK 536 Query: 520 KIKSSRDQALAERCLAALTECAASGDGNILAL----AVDASRARCTVGEITDAL 569 K S RD E ++ +A L L + G + A+ Sbjct: 537 KAISLRDSEFVEHMKNFISTNSADHVPPSLPLEKRKKIAIINVGAPAGGMNSAV 590 >6GYB-c nrPDB Length = 406 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 3/62 (4%) Query: 565 ITDALKKVFGEHKANDRMV---SGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAK 621 ++DA K E+ + SG Q+ ES S + + +E+ GRRP L Sbjct: 309 LSDAFKYAAAEYGPETTTIGVGSGIVTQQPFESNTARSMQQLAEQAVEKSGRRPATLTIN 368 Query: 622 MG 623 G Sbjct: 369 QG 370 >3O8O-A nrPDB Length = 787 Score = 29.7 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 22/148 (14%), Positives = 51/148 (34%), Gaps = 1/148 (0%) Query: 405 ARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIP 464 R II E + +P + + + L D + ++ ++ GG A A + Sbjct: 245 GRRNNTIIVAEGALDDQLNPVTANDVKDALIELGLDTKVTILGHVQ-RGGTAVAHDRWLA 303 Query: 465 KLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSS 524 L+ + ++G+ + ++ + VE + + + + + K S Sbjct: 304 TLQGVDAVKAVLEFTPETPSPLIGILENKIIRMPLVESVKLTKSVATAIENKDFDKAISL 363 Query: 525 RDQALAERCLAALTECAASGDGNILALA 552 RD E L+ +L ++ Sbjct: 364 RDTEFIELYENFLSTTVKDDGSELLPVS 391 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.128 0.324 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,554,844 Number of Sequences: 36641 Number of extensions: 985504 Number of successful extensions: 3016 Number of sequences better than 10.0: 31 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 2967 Number of HSP's gapped (non-prelim): 58 length of query: 750 length of database: 10,336,785 effective HSP length: 104 effective length of query: 646 effective length of database: 6,526,121 effective search space: 4215874166 effective search space used: 4215874166 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)