BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P21856 (447 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1LV0-A nrPDB 927 0.0 6C87-A nrPDB 526 e-150 1UKV-G nrPDB 511 e-145 3P1W-A nrPDB 476 e-135 1LTX-R nrPDB 118 5e-27 3MJ4-A nrPDB 35 0.069 5G1X-B nrPDB 33 0.18 1ITZ-A nrPDB 33 0.31 5NCC-A nrPDB 31 1.3 6CR0-A nrPDB 30 1.4 6MSO-A nrPDB 28 6.3 4Q0K-A nrPDB 28 6.4 >1LV0-A nrPDB Length = 449 Score = 927 bits (2395), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/447 (100%), Positives = 447/447 (100%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE Sbjct: 3 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 62 Query: 61 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP Sbjct: 63 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 122 Query: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 180 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD Sbjct: 123 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 182 Query: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 240 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR Sbjct: 183 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 242 Query: 241 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI 300 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI Sbjct: 243 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI 302 Query: 301 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT 360 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT Sbjct: 303 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT 362 Query: 361 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI 420 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI Sbjct: 363 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI 422 Query: 421 YKRMAGSAFDFENMKRKQNDVFGEADQ 447 YKRMAGSAFDFENMKRKQNDVFGEADQ Sbjct: 423 YKRMAGSAFDFENMKRKQNDVFGEADQ 449 >6C87-A nrPDB Length = 452 Score = 526 bits (1356), Expect = e-150, Method: Compositional matrix adjust. Identities = 252/435 (57%), Positives = 335/435 (77%), Gaps = 5/435 (1%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60 M+EEYDV+VLGTGLTEC++SG++SV+GKKVLHMDRNPYYGGES+S+ L++++++F+ + Sbjct: 9 MNEEYDVVVLGTGLTECVISGLLSVSGKKVLHMDRNPYYGGESASLN-LDQMFEKFRGQD 67 Query: 61 G-PPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRY-LDFKVVEGSFVYKGGKIYK 118 PP ++GR RD+N+DLIPKFLMANG+LVK+L T VTRY ++F +VEGSFVY G+I+K Sbjct: 68 AKPPASLGRSRDYNIDLIPKFLMANGKLVKILRMTGVTRYNMEFALVEGSFVYHKGEIHK 127 Query: 119 VPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLG 178 VP T TE + L+G FEK + +K + ++ ++D+N+PKT +G D +M +Y+ + + Sbjct: 128 VPITPTEVAKTPLLGFFEKLKAKKLVSYLYDYDQNNPKTHQGFDCSKDTMDKIYKYYGVS 187 Query: 179 QDVIDFTGHALALYRTDDYLDQ-PCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQG 237 +D DF GHA+ALY D Y+ P LE I R++LY +SL YGKSPY+YP+YGLGELPQ Sbjct: 188 EDTTDFLGHAVALYTDDSYMTTVPALEVIERMRLYEDSLNMYGKSPYVYPMYGLGELPQV 247 Query: 238 FARLSAIYGGTYMLNKPVDDIIME-NGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQ 296 FARL A+YGGTYML+K VD I+ + NG VVGV+S GEVA+CK ++ DPSY P++VRK G+ Sbjct: 248 FARLCAVYGGTYMLDKKVDRIVYDDNGHVVGVESGGEVAKCKMVVGDPSYFPEKVRKTGK 307 Query: 297 VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTT 356 VIR+ICILSHP+K+T +A S QII PQ Q RK DIY C+ S+ H+VA GKYIAI STT Sbjct: 308 VIRVICILSHPVKSTENAKSSQIIFPQKQTGRKHDIYCCVTSFTHHVAPNGKYIAIVSTT 367 Query: 357 VETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCND 416 VE+ +PE EV+ L+LL PID+KFV I D Y P++DG + VF S SYDATTHFE+ D Sbjct: 368 VESDNPENEVKVVLDLLNPIDEKFVYILDTYAPLEDGKKDGVFISKSYDATTHFESCAVD 427 Query: 417 IKDIYKRMAGSAFDF 431 I DIY+R+ G FD+ Sbjct: 428 IVDIYERITGEKFDW 442 >1UKV-G nrPDB Length = 453 Score = 511 bits (1315), Expect = e-145, Method: Compositional matrix adjust. Identities = 241/433 (55%), Positives = 333/433 (76%), Gaps = 8/433 (1%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQL-- 58 +D +YDVIVLGTG+TECILSG++SV+GKKVLH+D+ +YGGE++S+T L +LY++F+ Sbjct: 8 IDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVT-LSQLYEKFKQNP 66 Query: 59 --LEGPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKI 116 E G+ RDWNVDLIPKFLMANG+L +L++T+VTRY+DFK V GS+V+K GKI Sbjct: 67 ISKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDFKQVSGSYVFKQGKI 126 Query: 117 YKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFD 176 YKVP+ E EA++S LMG+FEKRR +KFL +++++ E+D T +G+D +M +VY KF Sbjct: 127 YKVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNTMDEVYYKFG 186 Query: 177 LGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQ 236 LG +F GHA+AL+ DDYL QP + RI LY +S+ARYGKSPYLYP+YGLGELPQ Sbjct: 187 LGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLGELPQ 246 Query: 237 GFARLSAIYGGTYMLNKPVDDIIM--ENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKA 294 GFARLSAIYGGTYML+ P+D+++ + GK GVK++ + +I DP+Y P++ + Sbjct: 247 GFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKST 306 Query: 295 GQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIA 353 GQ VIR ICIL+HP+ NT++A+S QIIIPQ+Q+ RKSDIYV ++S AHNV ++G Y+AI Sbjct: 307 GQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLAII 366 Query: 354 STTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETT 413 ST +ET P E+EPA +LL PI++KF+ I++L+EP +DGS+ ++ S SYDA++HFE+ Sbjct: 367 STIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESM 426 Query: 414 CNDIKDIYKRMAG 426 +D+KDIY R+ G Sbjct: 427 TDDVKDIYFRVTG 439 >3P1W-A nrPDB Length = 475 Score = 476 bits (1225), Expect = e-135, Method: Compositional matrix adjust. Identities = 237/457 (51%), Positives = 318/457 (69%), Gaps = 18/457 (3%) Query: 3 EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGP 62 E YDVI+LGTGL ECILSG++S GKK+L +DRNPYYGGE++S+ L LY F+ E Sbjct: 19 EHYDVIILGTGLKECILSGLLSHYGKKILVLDRNPYYGGETASLN-LTNLYNTFKPKENI 77 Query: 63 PETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGK------- 115 P G R WNVDLIPKF++ G LVK+L T VT YL++ VVEGS+VY+ K Sbjct: 78 PSKYGENRHWNVDLIPKFILVGGNLVKILKKTRVTNYLEWLVVEGSYVYQHQKKGFLTSE 137 Query: 116 --IYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYR 173 I+KVP+T+ EAL S L+ + EK R + F +V+ +D N T++ +DP +M ++Y+ Sbjct: 138 KFIHKVPATDMEALVSPLLSLMEKNRCKNFYQYVSEWDANKRNTWDNLDPYKLTMLEIYK 197 Query: 174 KFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGE 233 F+L Q IDF GHA+ALY DDYL QP T+ RIKLY +S++ +GKSP++YPLYGLG Sbjct: 198 HFNLCQLTIDFLGHAVALYLNDDYLKQPAYLTLERIKLYMQSISAFGKSPFIYPLYGLGG 257 Query: 234 LPQGFARLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKS-EGEVARCKQLICDPSYV---P 288 +P+GF+R+ AI GGT+MLNK V D + ++ KV G+KS +GE+A C ++ICDPSYV Sbjct: 258 IPEGFSRMCAINGGTFMLNKNVVDFVFDDDNKVCGIKSSDGEIAYCDKVICDPSYVMHLK 317 Query: 289 DRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGK 348 ++++K GQVIR ICILS+PI TN NSCQIIIPQNQ+NRKSDIY+ ++S+ H V +GK Sbjct: 318 NKIKKIGQVIRCICILSNPIPETNQTNSCQIIIPQNQLNRKSDIYINLVSFQHGVTLKGK 377 Query: 349 YIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATT 408 YIAI S TVET +P KE+E LELL I++KFV ISDLY +F + SYDAT+ Sbjct: 378 YIAIVSATVETNNPIKEIEKPLELLGTIEEKFVKISDLYVSTSKKPADNIFVTSSYDATS 437 Query: 409 HFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEA 445 HFET ND+ I++ + G +F+++ + GEA Sbjct: 438 HFETATNDLLQIWENLWGQKLNFDDLNTNAD---GEA 471 >1LTX-R nrPDB Length = 650 Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 63/220 (28%), Positives = 114/220 (51%), Gaps = 20/220 (9%) Query: 64 ETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTE 123 + + GR +N+DL+ K L + G L+ +L+ + V+RY +FK + ++ G + +VP + Sbjct: 216 QIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSR 275 Query: 124 TEALASNLMGMFEKRRFRKFLVFVANFDEN--DPKTFEGVDPQNTSMRDVYRKFDLGQDV 181 + S + M EKR KFL F ++E+ + + +EG T+ + + L ++ Sbjct: 276 ADVFNSKQLTMVEKRMLMKFLTFCVEYEEHPDEYRAYEG-----TTFSEYLKTQKLTPNL 330 Query: 182 IDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARL 241 F H++A+ ++ + K + + L RYG +P+L+PLYG GELPQ F R+ Sbjct: 331 QYFVLHSIAMTSETTSCT---VDGLKATKKFLQCLGRYGNTPFLFPLYGQGELPQCFCRM 387 Query: 242 SAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLI 281 A++GG Y L V ++++ E +CK +I Sbjct: 388 CAVFGGIYCLRHSVQCLVVDK----------ESRKCKAVI 417 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 21/47 (44%), Positives = 33/47 (70%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSIT 47 + ++DVIV+GTGL E I++ S +G++VLH+D YYGG +S + Sbjct: 5 LPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFS 51 >3MJ4-A nrPDB Length = 397 Score = 35.0 bits (79), Expect = 0.069, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 26/39 (66%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGES 43 +D +++G G +L+ ++ +G++VL +DR P+ GG + Sbjct: 30 FDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNA 68 >5G1X-B nrPDB Length = 63 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 22/36 (61%) Query: 34 DRNPYYGGESSSITPLEELYKRFQLLEGPPETMGRG 69 D + +Y G S P E+++K+F+LL PP + RG Sbjct: 5 DEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRG 40 >1ITZ-A nrPDB Length = 675 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 16/101 (15%) Query: 252 NKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRIICILSHPIKNT 311 NKP D+I V+G SE E+A + D +RK G+ +R++ +S + + Sbjct: 561 NKP--DLI-----VMGTGSELEIA---------AKAADELRKEGKTVRVVSFVSWELFDE 604 Query: 312 NDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAI 352 + ++P R S + + V AQGK I I Sbjct: 605 QSDEYKESVLPAAVTARISIEAGSTLGWQKYVGAQGKAIGI 645 >5NCC-A nrPDB Length = 594 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 24/36 (66%), Gaps = 1/36 (2%) Query: 3 EEYDVIVLGTGLTECILSGIMSVNG-KKVLHMDRNP 37 ++YD I++G G C+L+ +S +G K+VL ++ P Sbjct: 22 QKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGP 57 >6CR0-A nrPDB Length = 440 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 10/68 (14%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPE 64 YD IV+G G + + + +S G+ VL ++ GG + + L P E Sbjct: 9 YDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVV----------NFLGRPVE 58 Query: 65 TMGRGRDW 72 G G W Sbjct: 59 IGGAGVHW 66 >6MSO-A nrPDB Length = 585 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 111 YKGGKIYKVPSTETEALASNLMGMFEKRRFR 141 Y+G +++ VP + EAL+ + +F+KR FR Sbjct: 161 YRGDQVF-VPGNDEEALSRGVYDIFQKRNFR 190 >4Q0K-A nrPDB Length = 162 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 8/102 (7%) Query: 22 IMSVNGKKVLHMDRNPYYGGESSSIT-----PLEELYKRFQLLEGPPETMGRGRDWNVDL 76 I N + L++ + +S IT L + K Q++EG G G + Sbjct: 8 IKEFNTQTTLNVGLEALWAAQSKDITLVVPKVLPNIVKDVQVIEGDG---GVGTKLIFNF 64 Query: 77 IPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYK 118 +P N Q + Y E++ + +VVEG ++ +G YK Sbjct: 65 LPGIAPVNYQREVITEYDELSHTIGLQVVEGGYLNQGLSYYK 106 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1LV0-A nrPDB 758 0.0 3P1W-A nrPDB 686 0.0 6C87-A nrPDB 685 0.0 1UKV-G nrPDB 677 0.0 1LTX-R nrPDB 281 4e-76 Sequences not found previously or not previously below threshold: 3MJ4-A nrPDB 43 2e-04 5BR7-A nrPDB 38 0.009 1ZK7-A nrPDB 37 0.025 5EQD-A nrPDB 36 0.041 4RPJ-A nrPDB 35 0.055 1I8T-A nrPDB 35 0.064 6CR0-A nrPDB 34 0.17 4XB6-D nrPDB 33 0.19 2BXR-A nrPDB 33 0.19 5NCC-A nrPDB 33 0.23 3ATQ-A nrPDB 33 0.24 5KZL-A nrPDB 33 0.28 6C6P-A nrPDB 33 0.35 3IHG-A nrPDB 32 0.52 1O5W-A nrPDB 32 0.63 2QA2-A nrPDB 31 0.86 3Q6J-A nrPDB 31 0.88 5T5M-B nrPDB 31 0.92 6BRD-A nrPDB 31 1.4 3URH-A nrPDB 30 1.7 6N9U-E nrPDB 30 1.8 5IKN-D nrPDB 30 1.8 1CR4-A nrPDB 30 1.8 3KYB-A nrPDB 30 2.1 2B5D-X nrPDB 30 2.6 3I5J-B nrPDB 29 3.3 4MO2-B nrPDB 29 4.7 4CAZ-A nrPDB 29 5.2 2WOO-A nrPDB 28 9.5 >1LV0-A nrPDB Length = 449 Score = 758 bits (1956), Expect = 0.0, Method: Composition-based stats. Identities = 447/447 (100%), Positives = 447/447 (100%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE Sbjct: 3 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 62 Query: 61 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP Sbjct: 63 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 122 Query: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 180 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD Sbjct: 123 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 182 Query: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 240 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR Sbjct: 183 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 242 Query: 241 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI 300 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI Sbjct: 243 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRI 302 Query: 301 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT 360 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT Sbjct: 303 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT 362 Query: 361 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI 420 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI Sbjct: 363 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDI 422 Query: 421 YKRMAGSAFDFENMKRKQNDVFGEADQ 447 YKRMAGSAFDFENMKRKQNDVFGEADQ Sbjct: 423 YKRMAGSAFDFENMKRKQNDVFGEADQ 449 >3P1W-A nrPDB Length = 475 Score = 686 bits (1770), Expect = 0.0, Method: Composition-based stats. Identities = 237/457 (51%), Positives = 318/457 (69%), Gaps = 18/457 (3%) Query: 3 EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGP 62 E YDVI+LGTGL ECILSG++S GKK+L +DRNPYYGGE++S+ L LY F+ E Sbjct: 19 EHYDVIILGTGLKECILSGLLSHYGKKILVLDRNPYYGGETASLN-LTNLYNTFKPKENI 77 Query: 63 PETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGK------- 115 P G R WNVDLIPKF++ G LVK+L T VT YL++ VVEGS+VY+ K Sbjct: 78 PSKYGENRHWNVDLIPKFILVGGNLVKILKKTRVTNYLEWLVVEGSYVYQHQKKGFLTSE 137 Query: 116 --IYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYR 173 I+KVP+T+ EAL S L+ + EK R + F +V+ +D N T++ +DP +M ++Y+ Sbjct: 138 KFIHKVPATDMEALVSPLLSLMEKNRCKNFYQYVSEWDANKRNTWDNLDPYKLTMLEIYK 197 Query: 174 KFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGE 233 F+L Q IDF GHA+ALY DDYL QP T+ RIKLY +S++ +GKSP++YPLYGLG Sbjct: 198 HFNLCQLTIDFLGHAVALYLNDDYLKQPAYLTLERIKLYMQSISAFGKSPFIYPLYGLGG 257 Query: 234 LPQGFARLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKS-EGEVARCKQLICDPSYV---P 288 +P+GF+R+ AI GGT+MLNK V D + ++ KV G+KS +GE+A C ++ICDPSYV Sbjct: 258 IPEGFSRMCAINGGTFMLNKNVVDFVFDDDNKVCGIKSSDGEIAYCDKVICDPSYVMHLK 317 Query: 289 DRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGK 348 ++++K GQVIR ICILS+PI TN NSCQIIIPQNQ+NRKSDIY+ ++S+ H V +GK Sbjct: 318 NKIKKIGQVIRCICILSNPIPETNQTNSCQIIIPQNQLNRKSDIYINLVSFQHGVTLKGK 377 Query: 349 YIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATT 408 YIAI S TVET +P KE+E LELL I++KFV ISDLY +F + SYDAT+ Sbjct: 378 YIAIVSATVETNNPIKEIEKPLELLGTIEEKFVKISDLYVSTSKKPADNIFVTSSYDATS 437 Query: 409 HFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEA 445 HFET ND+ I++ + G +F+++ + GEA Sbjct: 438 HFETATNDLLQIWENLWGQKLNFDDLNTNAD---GEA 471 >6C87-A nrPDB Length = 452 Score = 685 bits (1768), Expect = 0.0, Method: Composition-based stats. Identities = 252/436 (57%), Positives = 335/436 (76%), Gaps = 5/436 (1%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60 M+EEYDV+VLGTGLTEC++SG++SV+GKKVLHMDRNPYYGGES+S+ L++++++F+ + Sbjct: 9 MNEEYDVVVLGTGLTECVISGLLSVSGKKVLHMDRNPYYGGESASLN-LDQMFEKFRGQD 67 Query: 61 G-PPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRY-LDFKVVEGSFVYKGGKIYK 118 PP ++GR RD+N+DLIPKFLMANG+LVK+L T VTRY ++F +VEGSFVY G+I+K Sbjct: 68 AKPPASLGRSRDYNIDLIPKFLMANGKLVKILRMTGVTRYNMEFALVEGSFVYHKGEIHK 127 Query: 119 VPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLG 178 VP T TE + L+G FEK + +K + ++ ++D+N+PKT +G D +M +Y+ + + Sbjct: 128 VPITPTEVAKTPLLGFFEKLKAKKLVSYLYDYDQNNPKTHQGFDCSKDTMDKIYKYYGVS 187 Query: 179 QDVIDFTGHALALYRTDDYLDQ-PCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQG 237 +D DF GHA+ALY D Y+ P LE I R++LY +SL YGKSPY+YP+YGLGELPQ Sbjct: 188 EDTTDFLGHAVALYTDDSYMTTVPALEVIERMRLYEDSLNMYGKSPYVYPMYGLGELPQV 247 Query: 238 FARLSAIYGGTYMLNKPVDDIIME-NGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQ 296 FARL A+YGGTYML+K VD I+ + NG VVGV+S GEVA+CK ++ DPSY P++VRK G+ Sbjct: 248 FARLCAVYGGTYMLDKKVDRIVYDDNGHVVGVESGGEVAKCKMVVGDPSYFPEKVRKTGK 307 Query: 297 VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTT 356 VIR+ICILSHP+K+T +A S QII PQ Q RK DIY C+ S+ H+VA GKYIAI STT Sbjct: 308 VIRVICILSHPVKSTENAKSSQIIFPQKQTGRKHDIYCCVTSFTHHVAPNGKYIAIVSTT 367 Query: 357 VETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCND 416 VE+ +PE EV+ L+LL PID+KFV I D Y P++DG + VF S SYDATTHFE+ D Sbjct: 368 VESDNPENEVKVVLDLLNPIDEKFVYILDTYAPLEDGKKDGVFISKSYDATTHFESCAVD 427 Query: 417 IKDIYKRMAGSAFDFE 432 I DIY+R+ G FD+ Sbjct: 428 IVDIYERITGEKFDWN 443 >1UKV-G nrPDB Length = 453 Score = 677 bits (1748), Expect = 0.0, Method: Composition-based stats. Identities = 241/436 (55%), Positives = 333/436 (76%), Gaps = 8/436 (1%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQL-- 58 +D +YDVIVLGTG+TECILSG++SV+GKKVLH+D+ +YGGE++S+T L +LY++F+ Sbjct: 8 IDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVT-LSQLYEKFKQNP 66 Query: 59 --LEGPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKI 116 E G+ RDWNVDLIPKFLMANG+L +L++T+VTRY+DFK V GS+V+K GKI Sbjct: 67 ISKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDFKQVSGSYVFKQGKI 126 Query: 117 YKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFD 176 YKVP+ E EA++S LMG+FEKRR +KFL +++++ E+D T +G+D +M +VY KF Sbjct: 127 YKVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNTMDEVYYKFG 186 Query: 177 LGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQ 236 LG +F GHA+AL+ DDYL QP + RI LY +S+ARYGKSPYLYP+YGLGELPQ Sbjct: 187 LGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLGELPQ 246 Query: 237 GFARLSAIYGGTYMLNKPVDDIIM--ENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKA 294 GFARLSAIYGGTYML+ P+D+++ + GK GVK++ + +I DP+Y P++ + Sbjct: 247 GFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKST 306 Query: 295 GQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIA 353 GQ VIR ICIL+HP+ NT++A+S QIIIPQ+Q+ RKSDIYV ++S AHNV ++G Y+AI Sbjct: 307 GQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLAII 366 Query: 354 STTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETT 413 ST +ET P E+EPA +LL PI++KF+ I++L+EP +DGS+ ++ S SYDA++HFE+ Sbjct: 367 STIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESM 426 Query: 414 CNDIKDIYKRMAGSAF 429 +D+KDIY R+ G Sbjct: 427 TDDVKDIYFRVTGHPL 442 >1LTX-R nrPDB Length = 650 Score = 281 bits (719), Expect = 4e-76, Method: Composition-based stats. Identities = 78/334 (23%), Positives = 148/334 (44%), Gaps = 38/334 (11%) Query: 64 ETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTE 123 + + GR +N+DL+ K L + G L+ +L+ + V+RY +FK + ++ G + +VP + Sbjct: 216 QIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSR 275 Query: 124 TEALASNLMGMFEKRRFRKFLVFVANFDEN--DPKTFEGVDPQNTSMRDVYRKFDLGQDV 181 + S + M EKR KFL F ++E+ + + +EG T+ + + L ++ Sbjct: 276 ADVFNSKQLTMVEKRMLMKFLTFCVEYEEHPDEYRAYEG-----TTFSEYLKTQKLTPNL 330 Query: 182 IDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARL 241 F H++A+ ++ + K + + L RYG +P+L+PLYG GELPQ F R+ Sbjct: 331 QYFVLHSIAMTSETTSCT---VDGLKATKKFLQCLGRYGNTPFLFPLYGQGELPQCFCRM 387 Query: 242 SAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQL-------------ICDPSYVP 288 A++GG Y L V ++++ E +CK + I + SY+ Sbjct: 388 CAVFGGIYCLRHSVQCLVVDK----------ESRKCKAVIDQFGQRIISKHFIIEDSYLS 437 Query: 289 DR-VRKAG--QVIRIICILSHPIKNTNDANSCQII-IPQNQVNRKSDIYVCMISYAHNVA 344 + + Q+ R + I + T+ I+ +P + + + + S Sbjct: 438 ENTCSRVQYRQISRAVLITDGSVLKTDADQQVSILTVPAEEPGSFAVRVIELCSSTM-TC 496 Query: 345 AQGKYIAIASTTVETTDPEKEVEPALELLEPIDQ 378 +G Y+ + T E +L P + Sbjct: 497 MKGTYLVHLTCMSSKTAREDLERVVQKLFTPYTE 530 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60 + ++DVIV+GTGL E I++ S +G++VLH+D YYGG +S + L + + Sbjct: 5 LPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFS-FSGLLSWLKEYQ 63 Query: 61 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYK 118 + + W + ++ N + + + + ++++ F Y ++K Sbjct: 64 ENNDVVTENSMWQ-----EQILENEEAIPLSSKDKTIQHVE------VFCYASQDLHK 110 >3MJ4-A nrPDB Length = 397 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 26/39 (66%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGES 43 +D +++G G +L+ ++ +G++VL +DR P+ GG + Sbjct: 30 FDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNA 68 >5BR7-A nrPDB Length = 393 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 3 EEYDVIVLGTGLTECILSG-IMSVNGKKVLHMDRNPYYGGESSS 45 ++D+IV+G+GL ++ S GKKVL +++ + GG + S Sbjct: 2 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYS 45 >1ZK7-A nrPDB Length = 467 Score = 36.5 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 25/59 (42%) Query: 177 LGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELP 235 LG + H A ++ D L E R+ ++ L G SP + P+ GL E P Sbjct: 104 LGGNPAITVVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESP 162 >5EQD-A nrPDB Length = 400 Score = 35.8 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 47/119 (39%), Gaps = 24/119 (20%) Query: 4 EYDVIVLGTGLTECILSG-IMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGP 62 +D+ V+G+G ++ + GK+VL ++R P+ GG + S E Sbjct: 4 NFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYS--------------EPE 49 Query: 63 PETMGRGRDWNVDLIPKFLMANGQLVKMLLY-TEVTRYLDFKVVEGSFVYKGGKIYKVP 120 PET + L F +N ++ + T+ T Y F G+ Y+ P Sbjct: 50 PETGIEVHKYGAHL---FHTSNKRVWDYVRQFTDFTGYQH-----RVFAMHNGQAYQFP 100 >4RPJ-A nrPDB Length = 399 Score = 35.4 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 24/122 (19%) Query: 1 MDEEYDVIVLGTGLTECILSGIMSVN-GKKVLHMDRNPYYGGESSSITPLEELYKRFQLL 59 M +D+ V+G+G ++ ++ K+VL ++R P+ GG + S Sbjct: 4 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYS-------------- 49 Query: 60 EGPPETMGRGRDWNVDLIPKFLMANGQLVKMLLY-TEVTRYLDFKVVEGSFVYKGGKIYK 118 E P+T + L F +N ++ + T+ T Y F G+ Y+ Sbjct: 50 EAEPQTGIEVHKYGAHL---FHTSNKRVWDYVRQFTDFTDYRH-----RVFAMHNGQAYQ 101 Query: 119 VP 120 P Sbjct: 102 FP 103 >1I8T-A nrPDB Length = 367 Score = 35.0 bits (79), Expect = 0.064, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 23/39 (58%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGES 43 YD I++G+GL + + + KKVL +++ + GG + Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNA 40 >6CR0-A nrPDB Length = 440 Score = 33.8 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 10/68 (14%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPE 64 YD IV+G G + + + +S G+ VL ++ GG + + L P E Sbjct: 9 YDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVVNFLGR----------PVE 58 Query: 65 TMGRGRDW 72 G G W Sbjct: 59 IGGAGVHW 66 >4XB6-D nrPDB Length = 281 Score = 33.5 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 27/55 (49%) Query: 337 ISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPID 391 +YA+ V G+Y+ S + +P+ ++ PAL+L +K + + ++ Sbjct: 169 TTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPPFTRVE 223 >2BXR-A nrPDB Length = 527 Score = 33.5 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 24/42 (57%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSI 46 +DV+V+G G++ + +++ G VL ++ GG + +I Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTI 55 >5NCC-A nrPDB Length = 594 Score = 33.1 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 20/105 (19%) Query: 3 EEYDVIVLGTGLTECILSGIMSVNG-KKVLHMDRNPYYGGESSSITPLEELYKRFQLLEG 61 ++YD I++G G C+L+ +S +G K+VL ++ P + + ++ Sbjct: 22 QKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGP------------DNTSRDVKIPAA 69 Query: 62 PPETMGRGRDWNV--DLIPKF-----LMANGQLVKMLLYTEVTRY 99 DWN+ +L + MA G+L+ T T Y Sbjct: 70 ITRLFRSPLDWNLFSELQEQLAERQIYMARGRLLGGSSATNATLY 114 >3ATQ-A nrPDB Length = 453 Score = 33.1 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYG------GESSSITPLEELYKRFQL 58 YDV+++G G + +S G K+L +D P+ G++ S ++L + Sbjct: 7 YDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPYPK 66 Query: 59 LEGPPETMGRGRDWNVDL 76 E + + ++ D+ Sbjct: 67 GEELENKINGIKLYSPDM 84 >5KZL-A nrPDB Length = 212 Score = 33.1 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 18/143 (12%) Query: 110 VYKGGKIYKVPSTETEALASNLM-GMFEK----RRFRKFLVFVANFDENDPKTFEGVDPQ 164 + + G + + E+ A + M G+ EK R F + +E + + + Sbjct: 13 ILREGTSEEHKAAESSAFIRSFMKGILEKGTYARHLEAFYYVYESMEEELERNKNNLVLK 72 Query: 165 NTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLET---INRIKLYSES----LA 217 + ++YRK L +D+ F G ++ +D+ QP + T + RI+ SE+ LA Sbjct: 73 SIYFPELYRKNALLEDLQFFYG----TWKPNDH--QPSVATQDYVQRIRKISETQPELLA 126 Query: 218 RYGKSPYLYPLYGLGELPQGFAR 240 + YL L G L + AR Sbjct: 127 AHSYVRYLGDLSGGQILKKVAAR 149 >6C6P-A nrPDB Length = 458 Score = 32.7 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 23/33 (69%) Query: 4 EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRN 36 + +VI++G G+ L+ ++S +G+KV ++R+ Sbjct: 7 DPEVIIVGAGVLGSALAAVLSRDGRKVTVIERD 39 >3IHG-A nrPDB Length = 535 Score = 31.9 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 2 DEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNP 37 D E DV+V+G GL + ++ G +VL ++R P Sbjct: 3 DHEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERRP 38 >1O5W-A nrPDB Length = 534 Score = 31.9 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 23/42 (54%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSI 46 +DV+V+G G++ + ++S VL ++ GG + ++ Sbjct: 22 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTV 63 >2QA2-A nrPDB Length = 499 Score = 31.2 bits (69), Expect = 0.86, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 27/62 (43%) Query: 3 EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGP 62 + VIV+G G +L+G + + G V+ +++ P GES + + F Sbjct: 11 SDASVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQRTGESRGLGFTARTMEVFDQRGIL 70 Query: 63 PE 64 P Sbjct: 71 PA 72 >3Q6J-A nrPDB Length = 523 Score = 31.2 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 19/40 (47%) Query: 2 DEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGG 41 EYD I +G G S + G + L +DR P+ GG Sbjct: 41 PREYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGG 80 >5T5M-B nrPDB Length = 432 Score = 31.2 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 50/131 (38%), Gaps = 11/131 (8%) Query: 206 INRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGG-TYMLNKPVDDIIMENGK 264 I+ + + L Y K L P+ G + GF ++ G Y ++ + G+ Sbjct: 266 IDTAIMMVQDLNDYAKWT-LIPMRGHYNV-TGFNQVCTWESGYPYCVDFSGGEPRYNPGE 323 Query: 265 VVGVKSEGEVARCKQLI---CDP-SYVPDRVRKAGQVIRIICILSHPIKNTNDANSCQII 320 G + ++ DP ++ P R + I +I I H T A+ II Sbjct: 324 T-GANDLLQNREADAMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMAD---II 379 Query: 321 IPQNQVNRKSD 331 IP V +++ Sbjct: 380 IPPAIVGMEAE 390 >6BRD-A nrPDB Length = 476 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 23/32 (71%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRN 36 +DVIV+G G T +L+G + ++G +VL +++ Sbjct: 2 FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKE 33 >3URH-A nrPDB Length = 491 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 21/119 (17%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSI-----TPLEELYKRFQLL 59 YD+IV+G+G + + + G KV +++ YGG ++ L + F Sbjct: 26 YDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMFHQA 85 Query: 60 EGPPETMGRGRDWNVDLI-PKFLMANGQLVKMLLYTEVTRYLDFKVVEG-SFVYKGGKI 116 + E +G V++ PK L KM+ + + T V+G SF++K KI Sbjct: 86 QHGLEALG------VEVANPKL-----NLQKMMAHKDATVK---SNVDGVSFLFKKNKI 130 >6N9U-E nrPDB Length = 566 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 11/133 (8%) Query: 177 LGQDVIDFTG-HALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPY-LYPLYGLGEL 234 + + D G H R D L + +E + + E +G + LY + E Sbjct: 346 VEETAEDLIGLHNRVRLRQSDSLKREIIENGKFDQWFDE---LFGNDTFHLYDSFAEAET 402 Query: 235 PQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKA 294 + A+L+ + G D II+++ +V V + GE K + + + + Sbjct: 403 DRLLAKLAYMRSGLGC-----DVIILDHISIV-VSASGESDERKMIDNLMTKLKGFAKST 456 Query: 295 GQVIRIICILSHP 307 G V+ +IC L +P Sbjct: 457 GVVLVVICHLKNP 469 >5IKN-D nrPDB Length = 486 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 11/133 (8%) Query: 177 LGQDVIDFTG-HALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPY-LYPLYGLGEL 234 + + D G H R D L + +E + + E +G + LY + E Sbjct: 283 VEETAEDLIGLHNRVRLRQSDSLKREIIENGKFDQWFDE---LFGNDTFHLYDSFAEAET 339 Query: 235 PQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKA 294 + A+L+ + G D II+++ +V V + GE K + + + + Sbjct: 340 DRLLAKLAYMRSGLGC-----DVIILDHISIV-VSASGESDERKMIDNLMTKLKGFAKST 393 Query: 295 GQVIRIICILSHP 307 G V+ +IC L +P Sbjct: 394 GVVLVVICHLKNP 406 >1CR4-A nrPDB Length = 296 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 11/133 (8%) Query: 177 LGQDVIDFTG-HALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPY-LYPLYGLGEL 234 + + D G H R D L + +E + + E +G + LY + E Sbjct: 76 VEETAEDLIGLHNRVRLRQSDSLKREIIENGKFDQWFDE---LFGNDTFHLYDSFAEAET 132 Query: 235 PQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKA 294 + A+L+ + G D II+++ +V V + GE K + + + + Sbjct: 133 DRLLAKLAYMRSGLGC-----DVIILDHISIV-VSASGESDERKMIDNLMTKLKGFAKST 186 Query: 295 GQVIRIICILSHP 307 G V+ +IC L +P Sbjct: 187 GVVLVVICHLKNP 199 >3KYB-A nrPDB Length = 390 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 21/37 (56%) Query: 7 VIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGES 43 ++++G G + ++ ++ G +V +D+ + GG S Sbjct: 6 ILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNS 42 >2B5D-X nrPDB Length = 528 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 48/130 (36%), Gaps = 6/130 (4%) Query: 95 EVTRYLDFKVVEGSFVYKG-GKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDEN 153 V R D ++EG Y+ GK+ V T A L M+ + + V V N++++ Sbjct: 115 NVFRSYDGNILEGFKKYQETGKLEIVTCNATHAFL-PLYQMYPEVVNAQITVGVKNYEKH 173 Query: 154 DPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYS 213 K G+ + +V F + A + D+ QP + R + Sbjct: 174 MKKHPRGIWLAECGYYQGLDLYLAQNNVEYFFVDSHAFWFADE---QPRY-GVYRPIMTP 229 Query: 214 ESLARYGKSP 223 + + + P Sbjct: 230 SGVFAFARDP 239 >3I5J-B nrPDB Length = 327 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 24/74 (32%) Query: 146 FVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLET 205 + + P + D + VYR ++L QD + +L + DQ E Sbjct: 54 WYKQYRNASPLKHDNWDAFTDPDQLVYRTYNLMQDGQESYVQSLFDQFNEREHDQMVREG 113 Query: 206 INRIKLYSESLARY 219 S RY Sbjct: 114 WEHTMARCYSPLRY 127 >4MO2-B nrPDB Length = 368 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 20/38 (52%) Query: 5 YDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGE 42 YD +++G+GL I + + G L +++ + GG Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGN 39 >4CAZ-A nrPDB Length = 490 Score = 28.8 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 50/156 (32%), Gaps = 29/156 (18%) Query: 315 NSCQIIIPQNQVNRKSDIYVCMISYAHN-VAAQGKYIAI-ASTTVETTDPEKEVEPALEL 372 S II P ++R +DI V ++ V G + I S E + L Sbjct: 256 KSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRIRL 315 Query: 373 LEPIDQK--------FVAISDLYEPIDDGSE-------------SQVFCSCSYDATTHFE 411 +P D+ F + + I+ G F +Y A T F Sbjct: 316 GDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFGKGAYVAPTVFT 375 Query: 412 TTCNDIKDIYKRMAGSAF------DFENMKRKQNDV 441 +D+ + + + G D + R+ ND Sbjct: 376 DCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDT 411 >2WOO-A nrPDB Length = 329 Score = 27.7 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 38/109 (34%), Gaps = 12/109 (11%) Query: 126 ALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFT 185 S + ++E R + L D ++ + + NT+ + + Q + Sbjct: 227 VCISEFLSLYETERMIQELT-SYEIDTHNIVVNQLLLDPNTTCPQCMARRKMQQ---KYL 282 Query: 186 GHALALYRTDDYLDQPCLE----TINRIKLYSESLARYGKSPYLYPLYG 230 LY + P + +K +SE L + PY+YP G Sbjct: 283 AQIEELYEDFHVVKVPQVPAEVRGTEALKSFSEMLVK----PYVYPTSG 327 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.137 0.367 Lambda K H 0.267 0.0416 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,374,197 Number of Sequences: 36641 Number of extensions: 719724 Number of successful extensions: 1926 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1861 Number of HSP's gapped (non-prelim): 55 length of query: 447 length of database: 10,336,785 effective HSP length: 100 effective length of query: 347 effective length of database: 6,672,685 effective search space: 2315421695 effective search space used: 2315421695 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)