BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P21589 (574 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4H2B-A nrPDB 1067 0.0 5H7W-A nrPDB 754 0.0 2Z1A-A nrPDB 324 8e-89 3ZTV-A nrPDB 179 3e-45 3IVD-A nrPDB 130 2e-30 1HP1-A nrPDB 121 9e-28 3GVE-A nrPDB 101 1e-21 3QFK-A nrPDB 70 3e-12 5EQV-A nrPDB 60 2e-09 3JYF-A nrPDB 60 3e-09 2WDE-A nrPDB 59 8e-09 5COV-A nrPDB 32 1.1 6CLW-A nrPDB 30 3.2 3OPY-B nrPDB 29 4.3 3D6W-A nrPDB 29 5.5 5NDX-A nrPDB 29 7.0 >4H2B-A nrPDB Length = 547 Score = 1067 bits (2760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 515/523 (98%), Positives = 519/523 (99%) Query: 27 WELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQ 86 WELTILHTNDVHSRLEQTSEDSSKCV+ASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQ Sbjct: 25 WELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQ 84 Query: 87 YQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKA 146 YQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI A Sbjct: 85 YQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANISA 144 Query: 147 KGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDK 206 GPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDK Sbjct: 145 SGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDK 204 Query: 207 LKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFI 266 LKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFI Sbjct: 205 LKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFI 264 Query: 267 VTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINK 326 VTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILL+SSIPEDPSIKADINK Sbjct: 265 VTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINK 324 Query: 327 WRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSM 386 WRIKLD+YSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRH DEMFWNHVSM Sbjct: 325 WRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADEMFWNHVSM 384 Query: 387 CILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQST 446 CILNGGGIRSPIDERN+GTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQST Sbjct: 385 CILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQST 444 Query: 447 GEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGD 506 GEFLQVGGIHVVYDLSRKPGDRVVKLDVLCT CRVPSYDPLKMDEVYKVILPNFLANGGD Sbjct: 445 GEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTSCRVPSYDPLKMDEVYKVILPNFLANGGD 504 Query: 507 GFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS 549 GFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS Sbjct: 505 GFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS 547 >5H7W-A nrPDB Length = 529 Score = 754 bits (1946), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/529 (69%), Positives = 438/529 (82%), Gaps = 2/529 (0%) Query: 25 GAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAG 84 G++ELTILHTNDVH+RLEQTS DS KC C GGVAR TK++QIR + NVLLLDAG Sbjct: 1 GSFELTILHTNDVHARLEQTSRDSGKCT-GEDCYGGVARRATKIRQIRASHRNVLLLDAG 59 Query: 85 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI 144 DQYQGTIWF YKG EV HFMN+LRYDAMALGNHEFDNG+ GL++PLLK KFPILSANI Sbjct: 60 DQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANI 119 Query: 145 KAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEV 204 + KGP+AS ISG LPYK++ VG E VGI+GYT+KETP LSNPG L F DE+ LQ Sbjct: 120 RPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHA 179 Query: 205 DKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYP 264 DKL TL VNKIIALGHSGF D IAQKV+GVDVVVGGH+NTFLYTG+PPS EV AG YP Sbjct: 180 DKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYP 239 Query: 265 FIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADI 324 F+ SDDGR+VPVVQAYAFGKYLGYL + FD++G VI + GNPILLN SI EDP++KA+I Sbjct: 240 FMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEI 299 Query: 325 NKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHV 384 ++ +++L NYS+QE+G+TIVYL+G++ +CRF ECN+GNLICDA++ NNLRH D+ WNHV Sbjct: 300 SRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHV 359 Query: 385 SMCILNGGGIRSPIDER-NNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYG 443 SMCI+NGGGIRSPIDE+ NNG IT E L AVLPFGGTFDL+Q+KGSTL++AFEHSVHR+G Sbjct: 360 SMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHG 419 Query: 444 QSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLAN 503 Q TGE LQV GI VVYDLS+KPG RVV L+VLCT+CRVP+Y PL+M++ YKV+LP+FLA Sbjct: 420 QGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAA 479 Query: 504 GGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGS 552 GGDG+ M+K + H SGD DI++V YI +M ++PA+EGR+ FS GS Sbjct: 480 GGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGS 528 >2Z1A-A nrPDB Length = 552 Score = 324 bits (830), Expect = 8e-89, Method: Compositional matrix adjust. Identities = 208/538 (38%), Positives = 305/538 (56%), Gaps = 27/538 (5%) Query: 13 LLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIR 72 L LG L A G + LT++HTND H+ LE S +GGVAR ++ Sbjct: 16 LAGLGRAL--AQGGFTLTLVHTNDTHAHLEPVELTLS---GEKTPVGGVARRVALFDRVW 70 Query: 73 RAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLL 132 N L LDAGD +QGT++F Y+G +FM+ LRY AMALGNHEFD G G + L Sbjct: 71 ARAKNPLFLDAGDVFQGTLYFNQYRGLADRYFMHRLRYRAMALGNHEFDLG-PGPLADFL 129 Query: 133 KEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLV 192 K A+F ++SAN+ A ++ GL+ PY V+ VG E VGI+G T+ +T +SNPG + Sbjct: 130 KGARFKVVSANVDAS--REPRLKGLFAPYAVVVVGGERVGIIGLTTPDTREISNPGPTVA 187 Query: 193 FEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGN 252 F D + Q V +L VNKI+ L H G+ D +A+++ GV V+VGGHS+T L G+ Sbjct: 188 FLDPYESAQKAVYELLAKGVNKIVVLSHLGYGEDLKLARRLVGVQVIVGGHSHTLL--GS 245 Query: 253 PPSKEV-PAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLN 311 P KE+ PAG YP +V + +G+ V VVQA+ +GK +G L++ FD +G +++ G +L+ Sbjct: 246 FPHKELSPAGPYPTVVKNPEGKDVLVVQAWEWGKVVGLLEVTFDAKGELLAYKGEALLMT 305 Query: 312 -SSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMIN 370 + PED K + + + Q + + V L G R RE N+GNLI D M+ Sbjct: 306 PEAAPEDFFAKEALLAYAQPVMALMQQVIAEAKVDLVGERAVVRRRESNLGNLITDGMLW 365 Query: 371 NNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGST 430 + + + NGGGIR+ I + G IT + VLPFG T ++ LKG Sbjct: 366 KTRNAGTQ-------IALQNGGGIRASIPK---GPITVGKVYEVLPFGNTLVVMDLKGKE 415 Query: 431 LKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMD 490 + A E+ V ++ + G FLQV G+ +DLSR G RVV+++V K Y PL ++ Sbjct: 416 ILAALENGVSQWENTAGRFLQVSGLRYAFDLSRPAGSRVVRVEVKTEK----GYVPLDLE 471 Query: 491 EVYKVILPNFLANGGDGFQMIKD-ELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIK 547 Y+V++ NF+ANGGDGF ++K+ + R D+G D Y+ ++KV+ +EGRI+ Sbjct: 472 ATYRVVVNNFIANGGDGFTVLKEAQGYRVDTGFSDAESFMDYLKELKVVEAGLEGRIE 529 >3ZTV-A nrPDB Length = 579 Score = 179 bits (454), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 160/536 (29%), Positives = 253/536 (47%), Gaps = 66/536 (12%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRC---MGGVARLFTKVQQIRRAEPNVL 79 A A EL+ILH ND HS LE ++ +N + +GG + + K+ ++R+ N L Sbjct: 7 AHKAVELSILHINDHHSYLE--PHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPL 64 Query: 80 LLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPI 139 +L AGD GT++FT++ G+ A MNA + LGNHEFD G EGL++ LL+ K P+ Sbjct: 65 VLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLK-LLEPLKIPV 123 Query: 140 LSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGY-TSKETPFLSNPGTNLVFEDEIT 198 LSAN+ +S + + PY + V E + I+G T +T S+PG ++ F DEI Sbjct: 124 LSANVIPDK--SSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIA 181 Query: 199 ALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEV 258 Q + LK +NKII L H+G E + IAQKV +DV+V G S+ S ++ Sbjct: 182 TAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKL 241 Query: 259 PA-GKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPED 317 P +YP + +G V V++ +A+ +G L ++F G + P +L SS Sbjct: 242 PVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSS--HK 299 Query: 318 PSIKADINKW-------------------RIKLDNYSTQELGKTIVYLDGSSQSCRFREC 358 +K KW I LD++ + Y S+ R + Sbjct: 300 LQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKY---KSEKDRLAQE 356 Query: 359 NMGNLICDAM-------INNN----------LRHTDEMFWNH---VSMCILNGGGIRSPI 398 +G + AM I N R E +N V + I N GG+R+ I Sbjct: 357 IVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADI 416 Query: 399 DERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVH--RYGQSTGEFLQVGGIH 456 G +T+ + LPFG T +++GS +K+ E ++ STG F GI Sbjct: 417 LP---GNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIR 473 Query: 457 VVYDLSRKP---GDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQ 509 Y+ + P G R+V ++VL + + ++P+ ++ Y V ++A G DG++ Sbjct: 474 --YEANETPNAEGKRLVSVEVLNKQTQ--QWEPIDDNKRYLVGTNAYVAGGKDGYK 525 >3IVD-A nrPDB Length = 509 Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 134/517 (25%), Positives = 226/517 (43%), Gaps = 72/517 (13%) Query: 26 AWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGD 85 A ++TI++TND+H+ +E + R +GG A + T V+Q + DAGD Sbjct: 4 AKDVTIIYTNDLHAHVEPYK--VPWIADGKRDIGGWANITTLVKQEKAKNKATWFFDAGD 61 Query: 86 QYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIK 145 + G ++ KG + MN + +DA+ +GNHEFD+G + + L +AKFPI+ NI Sbjct: 62 YFTGPYISSLTKGKAIIDIMNTMPFDAVTIGNHEFDHGWDNTLLQ-LSQAKFPIVQGNIF 120 Query: 146 AKGPLASQISGLYLPYKVLP---VGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQP 202 + S S PY ++ V V+G+ G + + + DEI LQ Sbjct: 121 YQN---SSKSFWDKPYTIIEKDGVKIGVIGLHGVFAFNDTVSAATRVGIEARDEIKWLQR 177 Query: 203 EVDKLKTLNVNKIIALGHSG----------------FEMDKLIAQKVRGVDVVVGGHSNT 246 +D+LK V+ +AL H G + D A +V+G+D+++ GH+ Sbjct: 178 YIDELKG-KVDLTVALIHEGVPARQSSMGGTDVRRALDKDIQTASQVKGLDILITGHA-- 234 Query: 247 FLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGN--VISSH 304 + G P +V I+++D G G +G L +++ E+ + + + Sbjct: 235 --HVGTPEPIKVGN---TLILSTDSG-----------GIDVGKLVLDYKEKPHNFTVKNF 278 Query: 305 GNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLI 364 + D K I+ W KLD Q + ++ V L + ++GNL Sbjct: 279 ELKTIYADEWKPDQQTKQVIDGWNKKLDEVVQQTVAQSPVEL----KRAYGESASLGNLA 334 Query: 365 CDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLV 424 DA++ ++T + + N GGIR+ I G IT + + PF + Sbjct: 335 ADALLAAAGKNT--------QLALTNSGGIRNEIPA---GAITMGGVISTFPFPNELVTM 383 Query: 425 QLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSY 484 +L G L+ EH S G G+ + YD S+ G RV+ L + + Sbjct: 384 ELTGKQLRSLMEHGASL---SNGVLQVSKGLEMKYDSSKPVGQRVITLTL--------NG 432 Query: 485 DPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSG 521 P++ VY + +FLA+GGDGF + R+ +G Sbjct: 433 KPIEDATVYHIATQSFLADGGDGFTAFTEGKARNITG 469 >1HP1-A nrPDB Length = 516 Score = 121 bits (303), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 136/537 (25%), Positives = 229/537 (42%), Gaps = 74/537 (13%) Query: 27 WELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQ 86 +++T+LHTND H + + G+ + ++ +VLLL GD Sbjct: 7 YKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRK------EVAAEGGSVLLLSGGDI 60 Query: 87 YQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKA 146 G + MN + YDAMA+GNHEFDN + ++ K AKFP+LSANI Sbjct: 61 NTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLT-VLRQQEKWAKFPLLSANIYQ 119 Query: 147 KGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPG--TNLVFE---DEITALQ 201 K S L+ P+ + D + ++G T+ +T + NP T++ F DE + Sbjct: 120 K----STGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVI 175 Query: 202 PEVDKLKTLNVNKIIALGHSGF------------EMDKLIAQKVRGVDVVVGGHSNTFLY 249 E+ + + ++ IIA H G +++ A + ++VGGHS + Sbjct: 176 QELQQTEKPDI--IIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVC 233 Query: 250 TGNPPSKE---VPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNV------ 300 K+ VP D + +VQA+ +GKY+G EF G + Sbjct: 234 MAAENKKQVDYVPGTP----CKPDQQNGIWIVQAHEWGKYVGRADFEF-RNGEMKMVNYQ 288 Query: 301 ---ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRE 357 ++ +L I E+ + + ++ ++ K ++G+T L+G RF + Sbjct: 289 LIPVNLKKKRVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQ 348 Query: 358 CNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPF 417 NMG LI A ++ +++GGGIR I+ G I+++N+ V PF Sbjct: 349 TNMGRLILAAQMDR----------TGADFAVMSGGGIRDSIEA---GDISYKNVLKVQPF 395 Query: 418 GGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCT 477 G + G + + +V + +G + Q + V K G KL+ L Sbjct: 396 GNVVVYADMTGKEVID-YLTAVAQMKPDSGAYPQFANVSFV----AKDG----KLNDL-- 444 Query: 478 KCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISK 534 K + DP K Y++ NF A GGDG+ + ++ ++G D V+ YI K Sbjct: 445 KIKGEPVDPAK---TYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYIQK 498 >3GVE-A nrPDB Length = 341 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 95/335 (28%), Positives = 145/335 (43%), Gaps = 59/335 (17%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLD 82 AA L+IL T D+H+ + D + G+AR +Q+ R PN LL+D Sbjct: 6 AAPQVHLSILATTDIHANMM----DYDYYSDKETADFGLARTAQLIQKHREQNPNTLLVD 61 Query: 83 AGD------------QYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEP 130 GD +YQ + K + MNAL+YDA LGNHEF+ G++ ++ Sbjct: 62 NGDLIQGNPLGEYAVKYQKDDIISGTKTHPIISVMNALKYDAGTLGNHEFNYGLD-FLDG 120 Query: 131 LLKEAKFPILSANIKAKGPLASQISGLYLPY----KVL--PVGDEVVGIVGYTSKETPFL 184 +K A FPI++AN+K + Y PY K L G+E VGY P + Sbjct: 121 TIKGADFPIVNANVK-----TTSGENRYTPYVINEKTLIDENGNEQKVKVGYIGFVPPQI 175 Query: 185 -----SNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKL----------I 229 N + +D + + + K+K + IIAL H+G E + Sbjct: 176 MTWDKKNLEGQVQVQDIVESANETIPKMKAEGADVIIALAHTGIEKQAQSSGAENAVFDL 235 Query: 230 AQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGY 289 A K +G+D ++ GH + PS E AG F V +PVV ++GKYLG Sbjct: 236 ATKTKGIDAIISGHQHGLF-----PSAEY-AGVAQFNVEKGTINGIPVVMPSSWGKYLGV 289 Query: 290 LKIEF----------DERGNVISSHGNPILLNSSI 314 + ++ D +G++ S GN N ++ Sbjct: 290 IDLKLEKADGSWKVADSKGSIESIAGNVTSRNETV 324 >3QFK-A nrPDB Length = 527 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 103/479 (21%), Positives = 189/479 (39%), Gaps = 76/479 (15%) Query: 68 VQQIRRAEPNVLLLDAGDQYQGTI---WFTVYKGAE--VAHFMNALRYDAMALGNHEFDN 122 ++Q RR +D GD QG+ + + G+ + F N + +D LGNHEF+ Sbjct: 55 IEQDRRQYDQSFKIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNY 114 Query: 123 GVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETP 182 G+ L + L+ +P+L ANI + +G+ K VGD+ VG++G T++ P Sbjct: 115 GLPYL-KDTLRRLNYPVLCANIYENDSTLTD-NGV----KYFQVGDQTVGVIGLTTQFIP 168 Query: 183 FLSNPG--TNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVV 240 P +L F LQ + ++K + + I+ H GFE D + +V+ Sbjct: 169 HWEQPEHIQSLTFHSAFEILQQYLPEMKR-HADIIVVCYHGGFEKD---LESGTPTEVLT 224 Query: 241 GGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGN- 299 G + + ++ + ++ ++ V+Q G +G + + DE N Sbjct: 225 GENEGYAMLEAFSKDIDIFITGHQHRQIAERFKQTAVIQPGTRGTTVGRVVLSTDEYENL 284 Query: 300 -VISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFREC 358 V S P++ +S+ +I D R +L+++ E+ T+ Y Sbjct: 285 SVESCELLPVIDDSTF----TIDEDDQHLRKQLEDWLDYEI-TTLPY------------- 326 Query: 359 NMGNLICDAMINNNLR-----HTDEMFWNHVSMCILNGGGIRSPIDERNNG---TITWEN 410 D IN+ H F N+ + + + + + +G +T + Sbjct: 327 -------DMTINHAFEARVAPHPFTNFMNYALLEKSDADVACTALFDSASGFKQVVTMRD 379 Query: 411 LAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGE------FLQVGGIHVVYDL--- 461 + PF TF ++ + G+ LK+A E S + E FL+ H YD+ Sbjct: 380 VINNYPFPNTFKVLAVSGAKLKEAIERSAEYFDVKNDEVSVSADFLEPKPQHFNYDIYGG 439 Query: 462 -------SRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKD 513 R G RV + + + + + Y + + N+ A GG + M D Sbjct: 440 VSYTIHVGRPKGQRVSNMMIQG--------HAVDLKQTYTICVNNYRAVGGGQYDMYID 490 >5EQV-A nrPDB Length = 340 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 76/297 (25%), Positives = 126/297 (42%), Gaps = 49/297 (16%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLD 82 +A +L +L T D+HS + K G+ R + + R+ N +L+D Sbjct: 4 SAATVDLRVLETTDLHSNMMDFDYYKDKPTEKF----GLVRTASLIIAARQQATNSVLVD 59 Query: 83 AGDQYQGTIW--FTVYKGAE------VAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKE 134 GD QG+ + KG V MN L Y +GNHEF+ G++ L + L Sbjct: 60 NGDVIQGSPLGDYIAAKGLNDGEIHPVYKAMNTLDYAVGNIGNHEFNYGLDYL-KKSLAG 118 Query: 135 AKFPILSAN---IKAKGPLASQISGLYLPYKVL--PVGDE-------VVGIVGYTSKETP 182 AKFP ++AN +K P L+ PY ++ PV D +G +G+ + Sbjct: 119 AKFPYVNANVIDVKTGKP-------LFQPYLIIDTPVKDRDGKSHNLRIGYIGFVPPQVM 171 Query: 183 FL--SNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMD--KLIAQ------- 231 +N + D + V +++ + ++A+ HSG D K +A+ Sbjct: 172 IWDKANLSGKVTVNDITETAKKWVPEMREQGADLVVAIPHSGLSSDPYKTMAENSVYYLS 231 Query: 232 KVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLG 288 +V G+D ++ GH++ PSK+ A K I T +P V +G +LG Sbjct: 232 QVPGIDAIMFGHAHGVF-----PSKDFAAIKGADI-TQGTLNGIPAVMPGQWGDHLG 282 >3JYF-A nrPDB Length = 339 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 72/304 (23%), Positives = 126/304 (41%), Gaps = 57/304 (18%) Query: 24 AGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDA 83 A +L I+ T D+HS + D +A+ G+ R + ++Q R N +L+D Sbjct: 4 AATVDLRIMETTDLHSNMM----DFDYYKDAATEKFGLVRTASLIEQARAEVKNSVLVDN 59 Query: 84 GDQYQGTIW--FTVYKGAE------VAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEA 135 GD QG+ + KG + V MN L Y LGNHEF+ G++ + L A Sbjct: 60 GDVIQGSPLGDYMAAKGLKEGDVHPVYKAMNTLNYAVGNLGNHEFNYGLD-FLHKALAGA 118 Query: 136 KFPILSANI---KAKGPLASQISGLYLPY-----KVLPVGDEV----VGIVGYTSKE--T 181 KFP ++ANI K P ++ PY +V+ ++ +G +G+ + T Sbjct: 119 KFPYVNANIIDAKTGKP-------MFTPYLIQDTRVVDSDGQIHTLRIGYIGFVPPQIMT 171 Query: 182 PFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIA---------QK 232 +N + D + + +++ + ++ + HSG D A + Sbjct: 172 WDKANLNGKVTVNDITETARKYIPEMRAKGADVVVVVAHSGLSADPYQAMAENSVYYLSQ 231 Query: 233 VRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGR----KVPVVQAYAFGKYLG 288 V GVD ++ GH++ P + I +D + VP V +G +LG Sbjct: 232 VPGVDAIMFGHAHAVF----------PGKDFANIKGADIAKGTLNGVPAVMPGMWGDHLG 281 Query: 289 YLKI 292 + + Sbjct: 282 VVDL 285 >2WDE-A nrPDB Length = 562 Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 54/206 (26%), Positives = 96/206 (46%), Gaps = 21/206 (10%) Query: 52 VNASRCMGGVARLFTKVQQIRRAEPNV-------LLLDAGDQYQGTIWFTVYKGAEVAHF 104 V +R G + + IR + V L+LD GD + + + +G V + Sbjct: 92 VELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRW 151 Query: 105 MNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISG--LYLPYK 162 N + D M + + E+ G E +E LL + LS NI + G L+ Y+ Sbjct: 152 QNLVGVDHM-VSHWEWTLGRE-RVEELLGLFRGEFLSYNI------VDDLFGDPLFPAYR 203 Query: 163 VLPVGDEVVGIVGYTSKETPFLSNPGT---NLVFEDEITALQPEVDKLKTLNVNKIIALG 219 + VG + +VG S +S+P + L F + LQ VDK + N ++ L Sbjct: 204 IHRVGPYALAVVG-ASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLS 262 Query: 220 HSGFEMDKLIAQKVRGVDVVVGGHSN 245 H+G ++D +A+++RG+D+++ GH++ Sbjct: 263 HNGMQLDAALAERIRGIDLILSGHTH 288 >5COV-A nrPDB Length = 340 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 25/88 (28%) Query: 121 DNGVEGLIEPLLKEA--KFPILSANI--------------KAKGPLASQISGLYLPYKVL 164 D GV I+ +KE ++P+LS + + +G L+ GL+LP Sbjct: 46 DRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQ---GLFLPMDRF 102 Query: 165 P------VGDEVVGIVGYTSKETPFLSN 186 P VGD+V I+G T E P +N Sbjct: 103 PELASNQVGDDVTEILGITKWEPPISTN 130 >6CLW-A nrPDB Length = 364 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 4/40 (10%) Query: 383 HVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFD 422 H+ + GG P+ ER G WE+LAA G FD Sbjct: 132 HILEALRTGG----PVHERTYGRPVWEDLAARPALGAAFD 167 >3OPY-B nrPDB Length = 941 Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust. Identities = 46/189 (24%), Positives = 70/189 (37%), Gaps = 30/189 (15%) Query: 62 ARLFTKVQQIRRAEPNVLLLDAG-DQYQGTIWFTVYKGAEVAHFMNALRYDA-------- 112 A LF I PN+ LL A D Y + F + K + F L D Sbjct: 4 ASLFNGTSFITLFAPNISLLQASIDFYTNFLGFAIRKNSNQKLFWLQLEEDQNNVSIQLI 63 Query: 113 ----MALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYL--------- 159 A + D + L L ++ + + +NI K S++ L Sbjct: 64 LDPEHAASVSQIDQNIRNLTRSLYRK-DWRSIQSNIAFKSSSLSKLVKLLKDGGHPVQQS 122 Query: 160 -----PYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLN-VN 213 P++V V D + ++G++ + PF N + L E A + E D K LN V Sbjct: 123 PNEISPFEVYTV-DPLGSLIGFSGFKNPFAVNERSLLPKVSEEKAYRAEDDSEKLLNPVR 181 Query: 214 KIIALGHSG 222 K I + SG Sbjct: 182 KTIGVMTSG 190 >3D6W-A nrPDB Length = 111 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 2/33 (6%) Query: 259 PAGKYPFIVTSDDGRKVPVVQAYA--FGKYLGY 289 P F+++ D+G +VPV Q+YA F K LG+ Sbjct: 77 PDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF 109 >5NDX-A nrPDB Length = 621 Score = 28.9 bits (63), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 6/57 (10%) Query: 459 YDLSRKPGDRVVKLDVLCT----KCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMI 511 +D+ +KPG + +++L T C+V + PL D+ ILP L GG +I Sbjct: 358 FDIIKKPG--LTSMELLATLGDTVCKVTAEPPLDPDQDGLAILPTRLPGGGVSISLI 412 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4H2B-A nrPDB 735 0.0 5H7W-A nrPDB 669 0.0 2Z1A-A nrPDB 550 e-157 1HP1-A nrPDB 431 e-121 3ZTV-A nrPDB 429 e-120 3IVD-A nrPDB 413 e-115 3QFK-A nrPDB 387 e-108 3GVE-A nrPDB 260 1e-69 3JYF-A nrPDB 240 1e-63 5EQV-A nrPDB 239 2e-63 2WDE-A nrPDB 203 2e-52 Sequences not found previously or not previously below threshold: 3C9F-A nrPDB 59 8e-09 2Q8U-A nrPDB 35 0.10 3DM5-A nrPDB 34 0.18 5JOY-A nrPDB 34 0.22 4N6K-A nrPDB 31 1.0 4RSM-A nrPDB 31 1.1 1RJ5-A nrPDB 30 3.6 4QKU-A nrPDB 29 7.7 4RS3-A nrPDB 28 9.0 >4H2B-A nrPDB Length = 547 Score = 735 bits (1896), Expect = 0.0, Method: Composition-based stats. Identities = 515/525 (98%), Positives = 519/525 (98%) Query: 25 GAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAG 84 WELTILHTNDVHSRLEQTSEDSSKCV+ASRCMGGVARLFTKVQQIRRAEPNVLLLDAG Sbjct: 23 PPWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAG 82 Query: 85 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI 144 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI Sbjct: 83 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI 142 Query: 145 KAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEV 204 A GPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEV Sbjct: 143 SASGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEV 202 Query: 205 DKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYP 264 DKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYP Sbjct: 203 DKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYP 262 Query: 265 FIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADI 324 FIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILL+SSIPEDPSIKADI Sbjct: 263 FIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADI 322 Query: 325 NKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHV 384 NKWRIKLD+YSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRH DEMFWNHV Sbjct: 323 NKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADEMFWNHV 382 Query: 385 SMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQ 444 SMCILNGGGIRSPIDERN+GTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQ Sbjct: 383 SMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQ 442 Query: 445 STGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANG 504 STGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCT CRVPSYDPLKMDEVYKVILPNFLANG Sbjct: 443 STGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTSCRVPSYDPLKMDEVYKVILPNFLANG 502 Query: 505 GDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS 549 GDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS Sbjct: 503 GDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS 547 >5H7W-A nrPDB Length = 529 Score = 669 bits (1726), Expect = 0.0, Method: Composition-based stats. Identities = 367/529 (69%), Positives = 438/529 (82%), Gaps = 2/529 (0%) Query: 25 GAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAG 84 G++ELTILHTNDVH+RLEQTS DS KC C GGVAR TK++QIR + NVLLLDAG Sbjct: 1 GSFELTILHTNDVHARLEQTSRDSGKCT-GEDCYGGVARRATKIRQIRASHRNVLLLDAG 59 Query: 85 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI 144 DQYQGTIWF YKG EV HFMN+LRYDAMALGNHEFDNG+ GL++PLLK KFPILSANI Sbjct: 60 DQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANI 119 Query: 145 KAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEV 204 + KGP+AS ISG LPYK++ VG E VGI+GYT+KETP LSNPG L F DE+ LQ Sbjct: 120 RPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHA 179 Query: 205 DKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYP 264 DKL TL VNKIIALGHSGF D IAQKV+GVDVVVGGH+NTFLYTG+PPS EV AG YP Sbjct: 180 DKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYP 239 Query: 265 FIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADI 324 F+ SDDGR+VPVVQAYAFGKYLGYL + FD++G VI + GNPILLN SI EDP++KA+I Sbjct: 240 FMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEI 299 Query: 325 NKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHV 384 ++ +++L NYS+QE+G+TIVYL+G++ +CRF ECN+GNLICDA++ NNLRH D+ WNHV Sbjct: 300 SRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHV 359 Query: 385 SMCILNGGGIRSPIDER-NNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYG 443 SMCI+NGGGIRSPIDE+ NNG IT E L AVLPFGGTFDL+Q+KGSTL++AFEHSVHR+G Sbjct: 360 SMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHG 419 Query: 444 QSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLAN 503 Q TGE LQV GI VVYDLS+KPG RVV L+VLCT+CRVP+Y PL+M++ YKV+LP+FLA Sbjct: 420 QGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAA 479 Query: 504 GGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGS 552 GGDG+ M+K + H SGD DI++V YI +M ++PA+EGR+ FS GS Sbjct: 480 GGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGS 528 >2Z1A-A nrPDB Length = 552 Score = 550 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 208/538 (38%), Positives = 304/538 (56%), Gaps = 27/538 (5%) Query: 13 LLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIR 72 L LG L A G + LT++HTND H+ LE S +GGVAR ++ Sbjct: 16 LAGLGRAL--AQGGFTLTLVHTNDTHAHLEPVELTLSG---EKTPVGGVARRVALFDRVW 70 Query: 73 RAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLL 132 N L LDAGD +QGT++F Y+G +FM+ LRY AMALGNHEFD G G + L Sbjct: 71 ARAKNPLFLDAGDVFQGTLYFNQYRGLADRYFMHRLRYRAMALGNHEFDLG-PGPLADFL 129 Query: 133 KEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLV 192 K A+F ++SAN+ A ++ GL+ PY V+ VG E VGI+G T+ +T +SNPG + Sbjct: 130 KGARFKVVSANVDAS--REPRLKGLFAPYAVVVVGGERVGIIGLTTPDTREISNPGPTVA 187 Query: 193 FEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGN 252 F D + Q V +L VNKI+ L H G+ D +A+++ GV V+VGGHS+T L G+ Sbjct: 188 FLDPYESAQKAVYELLAKGVNKIVVLSHLGYGEDLKLARRLVGVQVIVGGHSHTLL--GS 245 Query: 253 PPSKEV-PAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLN 311 P KE+ PAG YP +V + +G+ V VVQA+ +GK +G L++ FD +G +++ G +L+ Sbjct: 246 FPHKELSPAGPYPTVVKNPEGKDVLVVQAWEWGKVVGLLEVTFDAKGELLAYKGEALLMT 305 Query: 312 SS-IPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMIN 370 PED K + + + Q + + V L G R RE N+GNLI D M+ Sbjct: 306 PEAAPEDFFAKEALLAYAQPVMALMQQVIAEAKVDLVGERAVVRRRESNLGNLITDGMLW 365 Query: 371 NNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGST 430 + + + NGGGIR+ I + G IT + VLPFG T ++ LKG Sbjct: 366 KTRNAGTQ-------IALQNGGGIRASIPK---GPITVGKVYEVLPFGNTLVVMDLKGKE 415 Query: 431 LKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMD 490 + A E+ V ++ + G FLQV G+ +DLSR G RVV+++V K Y PL ++ Sbjct: 416 ILAALENGVSQWENTAGRFLQVSGLRYAFDLSRPAGSRVVRVEVKTEK----GYVPLDLE 471 Query: 491 EVYKVILPNFLANGGDGFQMIKD-ELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIK 547 Y+V++ NF+ANGGDGF ++K+ + R D+G D Y+ ++KV+ +EGRI+ Sbjct: 472 ATYRVVVNNFIANGGDGFTVLKEAQGYRVDTGFSDAESFMDYLKELKVVEAGLEGRIE 529 >1HP1-A nrPDB Length = 516 Score = 431 bits (1108), Expect = e-121, Method: Composition-based stats. Identities = 133/536 (24%), Positives = 227/536 (42%), Gaps = 68/536 (12%) Query: 25 GAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAG 84 +++T+LHTND H + + G+ + ++ +VLLL G Sbjct: 5 KTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRK------EVAAEGGSVLLLSGG 58 Query: 85 DQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI 144 D G + MN + YDAMA+GNHEFDN + ++ K AKFP+LSANI Sbjct: 59 DINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLT-VLRQQEKWAKFPLLSANI 117 Query: 145 KAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPG--TNLVFE---DEITA 199 K S L+ P+ + D + ++G T+ +T + NP T++ F DE Sbjct: 118 YQK----STGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKL 173 Query: 200 LQPEVDKLKTLNVNKIIALGHSGF------------EMDKLIAQKVRGVDVVVGGHSNTF 247 + E+ + + + IIA H G +++ A + ++VGGHS Sbjct: 174 VIQELQQTEKP--DIIIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDP 231 Query: 248 LYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNV------- 300 + K+V D + +VQA+ +GKY+G EF G + Sbjct: 232 VCMAAENKKQVDYVPGT-PCKPDQQNGIWIVQAHEWGKYVGRADFEF-RNGEMKMVNYQL 289 Query: 301 --ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFREC 358 ++ +L I E+ + + ++ ++ K ++G+T L+G RF + Sbjct: 290 IPVNLKKKRVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQT 349 Query: 359 NMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFG 418 NMG LI A ++ +++GGGIR I+ G I+++N+ V PFG Sbjct: 350 NMGRLILAAQMDR----------TGADFAVMSGGGIRDSIEA---GDISYKNVLKVQPFG 396 Query: 419 GTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTK 478 + G + + +V + +G + Q + V K G KL+ L K Sbjct: 397 NVVVYADMTGKEVID-YLTAVAQMKPDSGAYPQFANVSFV----AKDG----KLNDLKIK 447 Query: 479 CRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISK 534 +P+ + Y++ NF A GGDG+ + ++ ++G D V+ YI K Sbjct: 448 -----GEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYIQK 498 >3ZTV-A nrPDB Length = 579 Score = 429 bits (1103), Expect = e-120, Method: Composition-based stats. Identities = 165/584 (28%), Positives = 265/584 (45%), Gaps = 71/584 (12%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRC---MGGVARLFTKVQQIRRAEPNVL 79 A A EL+ILH ND HS LE ++ +N + +GG + + K+ ++R+ N L Sbjct: 7 AHKAVELSILHINDHHSYLEP--HETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPL 64 Query: 80 LLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPI 139 +L AGD GT++FT++ G+ A MNA + LGNHEFD G EGL++ LL+ K P+ Sbjct: 65 VLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLK-LLEPLKIPV 123 Query: 140 LSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGY-TSKETPFLSNPGTNLVFEDEIT 198 LSAN+ S + + PY + V E + I+G T +T S+PG ++ F DEI Sbjct: 124 LSANVIPDKS--SILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIA 181 Query: 199 ALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEV 258 Q + LK +NKII L H+G E + IAQKV +DV+V G S+ S ++ Sbjct: 182 TAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKL 241 Query: 259 P-AGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPED 317 P +YP + +G V V++ +A+ +G L ++F G + P +L SS Sbjct: 242 PVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSS--HK 299 Query: 318 PSIKADINKW-------------------RIKLDNYSTQELGKTIVYLDGSSQSCRFREC 358 +K KW I LD++ + Y S+ R + Sbjct: 300 LQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKY---KSEKDRLAQE 356 Query: 359 NMGNLICDAM-------INN----------NLRHTDEMFWNH---VSMCILNGGGIRSPI 398 +G + AM I N R E +N V + I N GG+R+ I Sbjct: 357 IVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADI 416 Query: 399 DERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVH--RYGQSTGEFLQVGGIH 456 G +T+ + LPFG T +++GS +K+ E ++ STG F GI Sbjct: 417 LP---GNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIR 473 Query: 457 VVYDLSRKP---GDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIK- 512 Y+ + P G R+V ++VL + + ++P+ ++ Y V ++A G DG++ Sbjct: 474 --YEANETPNAEGKRLVSVEVLNKQTQ--QWEPIDDNKRYLVGTNAYVAGGKDGYKTFGK 529 Query: 513 --DELLR--HDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGS 552 ++ D+ D ++ K +KF+ + Sbjct: 530 LFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFNAST 573 >3IVD-A nrPDB Length = 509 Score = 413 bits (1060), Expect = e-115, Method: Composition-based stats. Identities = 132/517 (25%), Positives = 225/517 (43%), Gaps = 72/517 (13%) Query: 26 AWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGD 85 A ++TI++TND+H+ +E + R +GG A + T V+Q + DAGD Sbjct: 4 AKDVTIIYTNDLHAHVEPYK--VPWIADGKRDIGGWANITTLVKQEKAKNKATWFFDAGD 61 Query: 86 QYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIK 145 + G ++ KG + MN + +DA+ +GNHEFD+G + + L +AKFPI+ NI Sbjct: 62 YFTGPYISSLTKGKAIIDIMNTMPFDAVTIGNHEFDHGWDNTLLQ-LSQAKFPIVQGNIF 120 Query: 146 AKGPLASQISGLYLPYKVLPVGDEVVGIVGY---TSKETPFLSNPGTNLVFEDEITALQP 202 + S S PY ++ +G++G + + + DEI LQ Sbjct: 121 YQN---SSKSFWDKPYTIIEKDGVKIGVIGLHGVFAFNDTVSAATRVGIEARDEIKWLQR 177 Query: 203 EVDKLKTLNVNKIIALGHSG----------------FEMDKLIAQKVRGVDVVVGGHSNT 246 +D+LK V+ +AL H G + D A +V+G+D+++ GH++ Sbjct: 178 YIDELKGK-VDLTVALIHEGVPARQSSMGGTDVRRALDKDIQTASQVKGLDILITGHAH- 235 Query: 247 FLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGN--VISSH 304 G P +V I+++D G G +G L +++ E+ + + + Sbjct: 236 ---VGTPEPIKVGNT---LILSTDSG-----------GIDVGKLVLDYKEKPHNFTVKNF 278 Query: 305 GNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLI 364 + D K I+ W KLD Q + ++ V L + ++GNL Sbjct: 279 ELKTIYADEWKPDQQTKQVIDGWNKKLDEVVQQTVAQSPVEL----KRAYGESASLGNLA 334 Query: 365 CDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLV 424 DA++ ++T + + N GGIR+ I G IT + + PF + Sbjct: 335 ADALLAAAGKNT--------QLALTNSGGIRNEIPA---GAITMGGVISTFPFPNELVTM 383 Query: 425 QLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSY 484 +L G L+ EH S G G+ + YD S+ G RV+ L + + Sbjct: 384 ELTGKQLRSLMEHGASL---SNGVLQVSKGLEMKYDSSKPVGQRVITLTL--------NG 432 Query: 485 DPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSG 521 P++ VY + +FLA+GGDGF + R+ +G Sbjct: 433 KPIEDATVYHIATQSFLADGGDGFTAFTEGKARNITG 469 >3QFK-A nrPDB Length = 527 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 112/532 (21%), Positives = 209/532 (39%), Gaps = 80/532 (15%) Query: 35 NDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTI--- 91 +DVH + T S N + M G+ ++Q RR +D GD QG+ Sbjct: 26 SDVHGYIFPTDFTSR---NQYQPM-GLLLANHVIEQDRRQYDQSFKIDNGDFLQGSPFCN 81 Query: 92 WFTVYKGA--EVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGP 149 + + G+ + F N + +D LGNHEF+ G+ ++ L+ +P+L ANI Sbjct: 82 YLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNYGLPY-LKDTLRRLNYPVLCANIYENDS 140 Query: 150 LASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPG--TNLVFEDEITALQPEVDKL 207 + +G+ K VGD+ VG++G T++ P P +L F LQ + ++ Sbjct: 141 TLTD-NGV----KYFQVGDQTVGVIGLTTQFIPHWEQPEHIQSLTFHSAFEILQQYLPEM 195 Query: 208 KTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIV 267 K + + I+ H GFE D + +V+ G + + ++ + Sbjct: 196 KR-HADIIVVCYHGGFEKDL---ESGTPTEVLTGENEGYAMLEAFSKDIDIFITGHQHRQ 251 Query: 268 TSDDGRKVPVVQAYAFGKYLGYLKIEFDERGN--VISSHGNPILLNSSIPEDPSIKADIN 325 ++ ++ V+Q G +G + + DE N V S P++ +S+ +I D Sbjct: 252 IAERFKQTAVIQPGTRGTTVGRVVLSTDEYENLSVESCELLPVIDDSTF----TIDEDDQ 307 Query: 326 KWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLR-----HTDEMF 380 R +L+++ E+ T+ Y D IN+ H F Sbjct: 308 HLRKQLEDWLDYEI-TTLPY--------------------DMTINHAFEARVAPHPFTNF 346 Query: 381 WNHVSMCILNGGGIRSPIDERNNG---TITWENLAAVLPFGGTFDLVQLKGSTLKKAFEH 437 N+ + + + + + +G +T ++ PF TF ++ + G+ LK+A E Sbjct: 347 MNYALLEKSDADVACTALFDSASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIER 406 Query: 438 SVHRYGQSTGE------FLQVGGIHVVYDL----------SRKPGDRVVKLDVLCTKCRV 481 S + E FL+ H YD+ R G RV + + Sbjct: 407 SAEYFDVKNDEVSVSADFLEPKPQHFNYDIYGGVSYTIHVGRPKGQRVSNMMIQG----- 461 Query: 482 PSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYIS 533 + + + Y + + N+ A GG + M D + D + ++ ++S Sbjct: 462 ---HAVDLKQTYTICVNNYRAVGGGQYDMYIDAPVVKDIQVEGAQLLIDFLS 510 >3GVE-A nrPDB Length = 341 Score = 260 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 93/340 (27%), Positives = 145/340 (42%), Gaps = 59/340 (17%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLD 82 AA L+IL T D+H+ + D + G+AR +Q+ R PN LL+D Sbjct: 6 AAPQVHLSILATTDIHANMM----DYDYYSDKETADFGLARTAQLIQKHREQNPNTLLVD 61 Query: 83 AGDQYQGTIW------------FTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEP 130 GD QG + K + MNAL+YDA LGNHEF+ G++ ++ Sbjct: 62 NGDLIQGNPLGEYAVKYQKDDIISGTKTHPIISVMNALKYDAGTLGNHEFNYGLD-FLDG 120 Query: 131 LLKEAKFPILSANIKAKGPLASQISGLYLPY------KVLPVGDE---VVGIVGYTSKE- 180 +K A FPI++AN+K + Y PY + G+E VG +G+ + Sbjct: 121 TIKGADFPIVNANVKT-----TSGENRYTPYVINEKTLIDENGNEQKVKVGYIGFVPPQI 175 Query: 181 -TPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKL----------I 229 T N + +D + + + K+K + IIAL H+G E + Sbjct: 176 MTWDKKNLEGQVQVQDIVESANETIPKMKAEGADVIIALAHTGIEKQAQSSGAENAVFDL 235 Query: 230 AQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGY 289 A K +G+D ++ GH + PS E AG F V +PVV ++GKYLG Sbjct: 236 ATKTKGIDAIISGHQHGLF-----PSAEY-AGVAQFNVEKGTINGIPVVMPSSWGKYLGV 289 Query: 290 LKIEF----------DERGNVISSHGNPILLNSSIPEDPS 319 + ++ D +G++ S GN N ++ Sbjct: 290 IDLKLEKADGSWKVADSKGSIESIAGNVTSRNETVTNTIQ 329 >3JYF-A nrPDB Length = 339 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 71/297 (23%), Positives = 121/297 (40%), Gaps = 43/297 (14%) Query: 24 AGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDA 83 A +L I+ T D+HS + D +A+ G+ R + ++Q R N +L+D Sbjct: 4 AATVDLRIMETTDLHSNMM----DFDYYKDAATEKFGLVRTASLIEQARAEVKNSVLVDN 59 Query: 84 GDQYQGTIW--FTVYKG------AEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEA 135 GD QG+ + KG V MN L Y LGNHEF+ G++ + L A Sbjct: 60 GDVIQGSPLGDYMAAKGLKEGDVHPVYKAMNTLNYAVGNLGNHEFNYGLD-FLHKALAGA 118 Query: 136 KFPILSANIKAKGPLASQISGLYLPY-----KVLPVGDE----VVGIVGYTSKE--TPFL 184 KFP ++ANI ++ PY +V+ + +G +G+ + T Sbjct: 119 KFPYVNANIIDAK----TGKPMFTPYLIQDTRVVDSDGQIHTLRIGYIGFVPPQIMTWDK 174 Query: 185 SNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIA---------QKVRG 235 +N + D + + +++ + ++ + HSG D A +V G Sbjct: 175 ANLNGKVTVNDITETARKYIPEMRAKGADVVVVVAHSGLSADPYQAMAENSVYYLSQVPG 234 Query: 236 VDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKI 292 VD ++ GH++ P K+ K I VP V +G +LG + + Sbjct: 235 VDAIMFGHAHAVF-----PGKDFANIKGADIAK-GTLNGVPAVMPGMWGDHLGVVDL 285 >5EQV-A nrPDB Length = 340 Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats. Identities = 71/298 (23%), Positives = 121/298 (40%), Gaps = 43/298 (14%) Query: 23 AAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLD 82 +A +L +L T D+HS + K G+ R + + R+ N +L+D Sbjct: 4 SAATVDLRVLETTDLHSNMMDFDYYKDKPTEK----FGLVRTASLIIAARQQATNSVLVD 59 Query: 83 AGDQYQGTIW--FTVYKG------AEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKE 134 GD QG+ + KG V MN L Y +GNHEF+ G++ ++ L Sbjct: 60 NGDVIQGSPLGDYIAAKGLNDGEIHPVYKAMNTLDYAVGNIGNHEFNYGLDY-LKKSLAG 118 Query: 135 AKFPILSANIKAKGPLASQISGLYLPYKVL--PVGDE-------VVGIVGYTSKETPFL- 184 AKFP ++AN+ L+ PY ++ PV D +G +G+ + Sbjct: 119 AKFPYVNANVI----DVKTGKPLFQPYLIIDTPVKDRDGKSHNLRIGYIGFVPPQVMIWD 174 Query: 185 -SNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLI---------AQKVR 234 +N + D + V +++ + ++A+ HSG D +V Sbjct: 175 KANLSGKVTVNDITETAKKWVPEMREQGADLVVAIPHSGLSSDPYKTMAENSVYYLSQVP 234 Query: 235 GVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKI 292 G+D ++ GH++ PSK+ A K I T +P V +G +LG + Sbjct: 235 GIDAIMFGHAHGVF-----PSKDFAAIKGADI-TQGTLNGIPAVMPGQWGDHLGVVDF 286 >2WDE-A nrPDB Length = 562 Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats. Identities = 101/517 (19%), Positives = 187/517 (36%), Gaps = 78/517 (15%) Query: 51 CVNASRCMGGVARLFTKVQQIRRAEPNV-------LLLDAGDQYQGTIWFTVYKGAEVAH 103 V +R G + + IR + V L+LD GD + + + +G V Sbjct: 91 FVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVR 150 Query: 104 FMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISG--LYLPY 161 + N + D M + + E+ G E +E LL + LS NI + G L+ Y Sbjct: 151 WQNLVGVDHM-VSHWEWTLGRE-RVEELLGLFRGEFLSYNI------VDDLFGDPLFPAY 202 Query: 162 KVLPVGDEVVGIVGYTSKETPFLSNPGT---NLVFEDEITALQPEVDKLKTLNVNKIIAL 218 ++ VG + +VG S +S+P + L F + LQ VDK + N ++ L Sbjct: 203 RIHRVGPYALAVVG-ASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLL 261 Query: 219 GHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVV 278 H+G ++D +A+++RG+D+++ GH++ P+ V K +V Sbjct: 262 SHNGMQLDAALAERIRGIDLILSGHTHDL-------------TPRPWRVG-----KTWIV 303 Query: 279 QAYAFGKYLGYLKIEFDERGNV-ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQ 337 A GK L + ++ + G + P+L P + + +L + Sbjct: 304 AGSAAGKALMRVDLKLWKGGIANLRVRVLPVL----AEHLPKAEDVEAFLKAQLAPHQDH 359 Query: 338 ELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSP 397 V + D ++ ++ + + ++ +R Sbjct: 360 LFTPLAVSETLLYKRDTLYST------WDQLVGEAVKAI------YPEVEVVFSPAVRWG 407 Query: 398 IDERNNGTITWENLAAVLPFG-GTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVG--- 453 ITW++L A F L L+G+ +K E S + Q G Sbjct: 408 TTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVS 467 Query: 454 ---GIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQM 510 G+ V D G+RV +++V PL + Y A GG ++ Sbjct: 468 RVFGLRYVLDPDAPTGERVREVEV--------GGRPLDPNRRYLAA-----AYGGRLQRV 514 Query: 511 IKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIK 547 + + V++ Y+ + + E +K Sbjct: 515 GEAKPGYEPRPIY--EVLAEYLRSVGRVRVRPEPNVK 549 >3C9F-A nrPDB Length = 557 Score = 58.7 bits (140), Expect = 8e-09, Method: Composition-based stats. Identities = 84/511 (16%), Positives = 164/511 (32%), Gaps = 79/511 (15%) Query: 28 ELTILHTNDVHS----RLEQTSEDSSKCVNASRCMGGVARLFTKVQQIR-RAEPNVLLLD 82 ++ +HT D H + Q ++ G T +++I ++LL+D Sbjct: 15 DINFVHTTDTHGWYSGHINQPLYHANW--------GDFISFTTHMRRIAHSRNQDLLLID 66 Query: 83 AGDQYQGTIWFTVYK--GAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKF--- 137 +GD++ G + G + YD + +GNHE E + Sbjct: 67 SGDRHDGNGLSDITSPNGLKSTPIFIKQDYDLLTIGNHEL-YLWENSKQEYETVVNHFQD 125 Query: 138 PILSANIKAKGPLASQISGLYLP----YKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVF 193 + +N+ + +GL++P YK + ++ + N GT + Sbjct: 126 KYVCSNVDIRLD-----NGLFVPLGLKYKYFTTPIRGIRVMAFGFLFDFKRFNSGTRVTP 180 Query: 194 EDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNP 253 E +P + V+ II +GH+ + +V + +L P Sbjct: 181 MAET-IHEPWFQEALKHEVDLIIIVGHTPISHNWGEFYQV-----------HQYLRQFFP 228 Query: 254 PSKEVPAGKYPFIVTSDDGRKVPV-VQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNS 312 + G + I + +Q+ + + +G+ + D + N + Sbjct: 229 DTIIQYFGGHSHIRDFTVFDSLSTGLQSGRYCETVGWTSVNLD------KADLNLPVRQR 282 Query: 313 SIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINN- 371 D K+ LD GK + L ++ + +G + + ++ Sbjct: 283 FSRSYIDFNTDSFKYHTNLDKEFDTAKGKLVSKLIRETRKELKLDTLIGYVKTNYYVDYV 342 Query: 372 NLRHTDEMF--------------WNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPF 417 + H +F + + I+N G IR + + G T ++ V PF Sbjct: 343 PIDHPKSIFNLLALKILKTLPKSKHEERITIINTGSIRYDLYK---GPYTIDSKFIVSPF 399 Query: 418 GGTFDLVQLK-------GSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVV 470 + + + + L A S R LQV DLS P Sbjct: 400 ENIWVNITVPKSVATKVAAKLNDADYISASRLKPPHQYDLQVQ------DLSTSPHQAHF 453 Query: 471 KLDVLCTKCRVPSYD-PLKMDEVYKVILPNF 500 ++ K V D D+ + NF Sbjct: 454 EMQEKLPKGYVTHDDFGADGDDTLHRAVVNF 484 >2Q8U-A nrPDB Length = 336 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 49/251 (19%), Positives = 79/251 (31%), Gaps = 39/251 (15%) Query: 27 WELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQ 86 EL ILHT+D H L TS SS+ V+ + + KV + L+L GD Sbjct: 17 KELKILHTSDWH--LGVTSWTSSRPVDRREE---LKKALDKVVEEAEKREVDLILLTGDL 71 Query: 87 Y---QGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSAN 143 ++ + M + GNH++ K K L N Sbjct: 72 LHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDW------------KGLK---LFGN 116 Query: 144 IKAKGPLASQISGLYLPYKVLPVGDEVVGIVGY-TSKETPFLSNPGTNLVFEDEITALQP 202 + P V + V I+ + E+ L + F E + Sbjct: 117 FVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKL 176 Query: 203 EVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVG-------------GHSNTFLY 249 + LK + I +GH E A +G ++++ GH ++F Sbjct: 177 YEEALKKE--DFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFRE 234 Query: 250 TGNPPSKEVPA 260 P P Sbjct: 235 IQKQPLTIYPG 245 >3DM5-A nrPDB Length = 443 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 33/102 (32%), Gaps = 11/102 (10%) Query: 162 KVLPVGDEVVGIVGYTSKETPFLSNPGTNL-----------VFEDEITALQPEVDKLKTL 210 + VG+V + L +D I + VD K+ Sbjct: 122 RYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRYHIEVFGNPQEKDAIKLAKEGVDYFKSK 181 Query: 211 NVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGN 252 V+ II + DK + ++++ + V+ H + G Sbjct: 182 GVDIIIVDTAGRHKEDKALIEEMKQISNVIHPHEVILVIDGT 223 >5JOY-A nrPDB Length = 516 Score = 33.6 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 31/207 (14%) Query: 76 PNVLLLDAGDQ-----YQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEP 130 N +L A + QGT + +G + + +M L Y M +H G E + P Sbjct: 222 ANPILTHANESGQSSPIQGTGHADLVEGTDGSWWMVCLAYRIMPGTHH--TLGRETYLAP 279 Query: 131 LLKEAK--FPILSAN----IKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFL 184 ++ K +P++++N +K P Q P ++ D G + S E L Sbjct: 280 -VRWDKDAWPVVNSNGTISLKMDVPTLPQQEMKGRPERI----DFKEGKL---SPEWIHL 331 Query: 185 SNPGTN--LVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKL---IAQKVR----- 234 NP + +D L L +AL F+M+ + QK Sbjct: 332 QNPEAKNYIFTKDGKLRLIATPVTLSDWKSPTFVALRQEHFDMEASAPVVLQKAGVNDEA 391 Query: 235 GVDVVVGGHSNTFLYTGNPPSKEVPAG 261 G+ V + HS+ L+ ++ G Sbjct: 392 GISVFMEFHSHYDLFVRQDKDRKRSVG 418 >4N6K-A nrPDB Length = 351 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 52/170 (30%), Gaps = 11/170 (6%) Query: 209 TLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVT 268 + + L H F + +++ + V + ++ + P ++PA K Sbjct: 26 ADDYKLTLKLSHV-FSPAEQLSKSMDAVAESIYEKTDGAINIQTFPQAQLPAYKEGVEQV 84 Query: 269 SDDGRKVPVVQAYAFGKYLGYLKI--------EFDERGNVISSHGNPILLNSSIPEDPSI 320 + + V G Y+ K FDE N+ S + E I Sbjct: 85 VRGAKFISVEDPSFIGDYVPDFKALYAPMLYRSFDEYVNLTQSDLVKKMQAE--AEKQGI 142 Query: 321 KADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMIN 370 K + N TQ++ KT L G + + L + Sbjct: 143 KILALDYIYGFRNLITQKVIKTPADLKGMKIRTPGSKSYIDTLTAMGAVA 192 >4RSM-A nrPDB Length = 327 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 64/179 (35%), Gaps = 10/179 (5%) Query: 192 VFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQ-KVRGVDVV-VGGHSNTFLY 249 +++ +VD + V+ II + + +A K +G+ +V V ++ Sbjct: 48 SANLDVSTQASQVDSMINQGVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDSKDI 107 Query: 250 TGNPPSKEVPAGKYPFIVTSDD--GRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNP 307 GN +V AG + +D G+ V+ G+ G L + Sbjct: 108 AGNVQPDDVAAGAQEMQMMADRLGGKGNIVILQGPLGQS-GELDRSKGIEQVLAKYPDIK 166 Query: 308 IL--LNSSIPEDPS---IKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMG 361 +L ++ D + +K I+ + ++D Q + L +S R +G Sbjct: 167 VLAKDTANWKRDEAVNKMKNWISGFGPQIDGVVAQNDDMGLGALQALKESGRTGVPIVG 225 >1RJ5-A nrPDB Length = 261 Score = 29.8 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 20/58 (34%), Gaps = 1/58 (1%) Query: 274 KVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKL 331 +P VQ + + LG ++ G+ + P L +P + W + Sbjct: 43 DLPAVQPHGY-DQLGTEPLDLHNNGHTVQLSLPPTLHLGGLPRKYTAAQLHLHWGQRG 99 >4QKU-A nrPDB Length = 441 Score = 28.6 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 51/154 (33%), Gaps = 19/154 (12%) Query: 251 GNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILL 310 G SK P+IVT D V Q + L YL+ + L Sbjct: 271 GPFNSKGFATTISPWIVTLDALEPFRVAQPEQSPQPLAYLR---HAGKHAFDIALEVTLR 327 Query: 311 NSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMIN 370 E SI + + + + + + + +G+L+ I+ Sbjct: 328 AEGAAEATSICRTNFR-------HMYWTMAQQLAH-----HTVAGCNTRVGDLMGSGTIS 375 Query: 371 NNLRHTD----EMFWNHVSMCILNGGGIRSPIDE 400 + + E+ WN LNGGG R+ I++ Sbjct: 376 GPTKDSFGSLLELTWNGKEPVALNGGGSRTFIED 409 >4RS3-A nrPDB Length = 327 Score = 28.2 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 63/179 (35%), Gaps = 10/179 (5%) Query: 192 VFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQ-KVRGVDVV-VGGHSNTFLY 249 ++++ +VD L V+ II + + +A K +G+ ++ V T Sbjct: 48 SANNDVSTQASQVDSLINQGVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALETPDL 107 Query: 250 TGNPPSKEVPAGKYPFIVTSDD--GRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNP 307 GN +V AG + +D G+ V+ G G + + Sbjct: 108 AGNVQPDDVAAGAQEMQMMADRLGGKGNIVILQGPLGGS-GEINRGKGIDQVLAKYPDIK 166 Query: 308 IL--LNSSIPEDPS---IKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMG 361 +L ++ D + +K I+ + ++D Q + L ++ R +G Sbjct: 167 VLAKDTANWKRDEAVNKMKNWISSFGPQIDGVVAQNDDMGLGALQALKEAGRTGVPIVG 225 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.123 0.302 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,422,901 Number of Sequences: 36641 Number of extensions: 741853 Number of successful extensions: 2165 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 2025 Number of HSP's gapped (non-prelim): 40 length of query: 574 length of database: 10,336,785 effective HSP length: 102 effective length of query: 472 effective length of database: 6,599,403 effective search space: 3114918216 effective search space used: 3114918216 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.2 bits)