BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P21524 (888 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2ZLF-A nrPDB 1861 0.0 5D1Y-A nrPDB 1098 0.0 2WGH-A nrPDB 1010 0.0 5IM3-A nrPDB 538 e-153 5R1R-A nrPDB 238 6e-63 6DQW-A nrPDB 201 1e-51 6DQX-A nrPDB 182 6e-46 6CGM-A nrPDB 179 3e-45 1PEQ-A nrPDB 170 3e-42 3O0O-A nrPDB 160 2e-39 2G3Y-A nrPDB 33 0.54 6F74-A nrPDB 32 0.83 2CJW-A nrPDB 32 0.87 3W4R-A nrPDB 32 1.0 3P8T-A nrPDB 31 2.4 6G2J-O nrPDB 30 5.1 4N14-A nrPDB 30 5.9 4V89-AW nrPDB 30 6.5 >2ZLF-A nrPDB Length = 888 Score = 1861 bits (4821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 888/888 (100%), Positives = 888/888 (100%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 Query: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 Query: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 Query: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 Query: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 Query: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 Query: 361 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG 420 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG Sbjct: 361 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG 420 Query: 421 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN 480 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN Sbjct: 421 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN 480 Query: 481 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY 540 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY Sbjct: 481 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY 540 Query: 541 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS 600 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS Sbjct: 541 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS 600 Query: 601 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK 660 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK Sbjct: 601 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK 660 Query: 661 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT 720 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT Sbjct: 661 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT 720 Query: 721 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM 780 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM Sbjct: 721 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM 780 Query: 781 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE 840 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE Sbjct: 781 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE 840 Query: 841 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG 888 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG Sbjct: 841 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG 888 >5D1Y-A nrPDB Length = 812 Score = 1098 bits (2840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/760 (67%), Positives = 635/760 (83%), Gaps = 6/760 (0%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 M+V KRDGR+E V FDKIT+RI +LCYGL+ +D ++T ++I G+Y GVTT+ELD LA Sbjct: 21 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 80 Query: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 AET A +TT HPDYA LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ Sbjct: 81 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 140 Query: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 +IV+ NKD+LNSAI+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH Sbjct: 141 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 200 Query: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 DI+AA+ETYNL+S ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CAL Sbjct: 201 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 260 Query: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 ISK+AGGIG+ + IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+Y Sbjct: 261 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 320 Query: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 LEPWH DIF+F+D++KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL Sbjct: 321 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 380 Query: 361 DCYGDEFEALYTRYEKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419 + +G+EFE LY YEK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NL Sbjct: 381 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 440 Query: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTR 479 G IK SNLC EIVEY++ DE AVCNLAS+AL ++ TSE TY+FKKL E+ KVV R Sbjct: 441 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-TSE----HTYDFKKLAEVTKVVVR 495 Query: 480 NLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETI 539 NLN++ID NYYPV EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETI Sbjct: 496 NLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETI 555 Query: 540 YHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRN 599 Y+ ++EASC+LA++ GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RN Sbjct: 556 YYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRN 615 Query: 600 SLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGM 659 SL +APMPTAST+QILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E M Sbjct: 616 SLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEM 675 Query: 660 KQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAP 719 K +I NGSIQ +P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P Sbjct: 676 KNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 735 Query: 720 TMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQK 759 GKLTSMHFYGWK+GLKTGMYYLRT+ A+ IQFT++++ Sbjct: 736 NYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKE 775 >2WGH-A nrPDB Length = 676 Score = 1010 bits (2611), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/674 (68%), Positives = 568/674 (84%), Gaps = 6/674 (0%) Query: 75 ATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSA 134 A LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ +IV+ NKD+LNSA Sbjct: 2 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 61 Query: 135 IVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMS 194 I+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH DI+AA+ETYNL+S Sbjct: 62 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 121 Query: 195 LKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHN 254 ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CALISK+AGGIG+ + Sbjct: 122 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 181 Query: 255 IRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDI 314 IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+YLEPWH DIF+F+D+ Sbjct: 182 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 241 Query: 315 RKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRY 374 +KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL + +G+EFE LY Y Sbjct: 242 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 301 Query: 375 EKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVE 433 EK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NLG IK SNLC EIVE Sbjct: 302 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 361 Query: 434 YSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVE 493 Y++ DE AVCNLAS+AL ++ TSE TY+FKKL E+ KVV RNLN++ID NYYPV Sbjct: 362 YTSKDEVAVCNLASLALNMYV-TSE----HTYDFKKLAEVTKVVVRNLNKIIDINYYPVP 416 Query: 494 EARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQK 553 EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETIY+ ++EASC+LA++ Sbjct: 417 EACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKE 476 Query: 554 DGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQ 613 GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RNSL +APMPTAST+Q Sbjct: 477 QGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQ 536 Query: 614 ILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGL 673 ILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E MK +I NGSIQ + Sbjct: 537 ILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSI 596 Query: 674 PNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWK 733 P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P GKLTSMHFYGWK Sbjct: 597 PEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWK 656 Query: 734 KGLKTGMYYLRTQA 747 +GLKTGMYYLRT+A Sbjct: 657 QGLKTGMYYLRTRA 670 >5IM3-A nrPDB Length = 963 Score = 538 bits (1385), Expect = e-153, Method: Compositional matrix adjust. Identities = 309/784 (39%), Positives = 447/784 (57%), Gaps = 42/784 (5%) Query: 3 VYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAE 62 + + DG P+ ++ IS C GL +D + + + +Y+GV +++ Sbjct: 150 ITRADGSLSPLDMGRLNTIISEACEGL--AEVDGALIERETLKNLYDGVAEKDVNTALVM 207 Query: 63 TCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNA---ATGKPAPMISDD 119 T + P+Y+ + AR+ + L + F V E + A A PA + Sbjct: 208 TARTLVEREPNYSYVTARLLMDTLRAEALG-FLGVAESATHHEMAELYAKALPAYIEKGA 266 Query: 120 VYNIVME-----NKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRV 174 + +V + +KL AI ++RD Q++Y G +TL Y + +G E PQ MRV Sbjct: 267 EFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDRYFIHKDGIRFELPQIFFMRV 326 Query: 175 ALG--IHGRDIEA-ALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGI 231 A+G I +D EA A+E YNL+S + ++PTLFNAGT +PQ+SSC+L + +D + GI Sbjct: 327 AMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTLFNAGTLRPQLSSCYLTTVPDD-LSGI 385 Query: 232 YDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGN 291 Y + + A++SK AGG+G +R+ GSYI GTNG S G++P ++V N+TA V+QGG Sbjct: 386 YGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQGG- 444 Query: 292 KRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLF 351 KR GA YLE WH DI +F+++RKN G + R D+ A WIPDLFMKRV ++G+WTLF Sbjct: 445 KRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDGSWTLF 504 Query: 352 SPTSAPGLSDCYGDEFEALYTRYE------KEGRGKTIKAQKLWYSILEAQTETGTPFVV 405 SP+ P L D YG FE Y YE K K ++A+ LW +L ETG P++ Sbjct: 505 SPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHKVVQAKDLWRKMLSMLFETGHPWLT 564 Query: 406 YKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTY 465 +KD CN +S Q+++GV+ SSNLC EI + DE AVCNL S+ L I DGK T Sbjct: 565 FKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIV---DGKLDT- 620 Query: 466 NFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDS 525 KL + K R L+ VID NYY V +A+ SN +HRP+ LG+ G D L +P+ S Sbjct: 621 --AKLEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLGIMGFQDALYLQHIPYGS 678 Query: 526 EEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFD----MWDQKPYG 581 + A Q E I + +++ASC+LA + G Y+TFQGS SQGIL D + +++ Sbjct: 679 DAAIAFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQGILPIDSEKKLIEERGAK 738 Query: 582 --------MWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRV 633 DW LR+ + K G+RNS MA PTA+ + I G ++ EP N+Y + Sbjct: 739 YIEVDLSETLDWAPLRERVQK-GIRNSNIMAIAPTATIANITGVSQSIEPTYQNLYVKSN 797 Query: 634 LSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQK 693 LSGEF V+NPYL+RDL G+WD M L +GS+Q + +PQ+LKDLY T +E+ + Sbjct: 798 LSGEFTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDLYATAFEVETR 857 Query: 694 TIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQ 753 I+ A+ R +IDQ+ SLNL++ + KL + W +GLKT YYLR AA++ + Sbjct: 858 WIVEAASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGLKT-TYYLRALAATSTEK 916 Query: 754 FTID 757 TI+ Sbjct: 917 STIN 920 >5R1R-A nrPDB Length = 761 Score = 238 bits (608), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 222/808 (27%), Positives = 352/808 (43%), Gaps = 93/808 (11%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 + V KRDG E + DKI + GL I V++ I Y+G+ T ++ Sbjct: 5 LLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHI--QFYDGIKTSDIHETI 62 Query: 61 AETCAYMTTVH-PDYATLAARIAISNLHKQTTKQFSKVVEDLYRYV--NAATGKPAPMIS 117 + A + + PDY LAAR+AI +L K+ QF LY +V GK + Sbjct: 63 IKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPA--LYDHVVKMVEMGKYDNHLL 120 Query: 118 DDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLL--RINGQVAERPQHLIMRVA 175 +D E ++++ I +DRD +SY K LE YL+ R+ G++ E Q L + VA Sbjct: 121 EDY---TEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVA 177 Query: 176 LGIHGR-----DIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEG 230 + ++ Y+ +S + +P + TP Q SSC L+ DS++ Sbjct: 178 ACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECG-DSLDS 236 Query: 231 IYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGG 290 I T GIG++ IR+ GS I G G IP + F + QGG Sbjct: 237 INATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG 296 Query: 291 NKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTL 350 R GA L+ WH ++ + ++ N G E R R + + I L R+ + TL Sbjct: 297 -VRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITL 355 Query: 351 FSPTSAPGLSDCY---GDEFEALYTRYEKEG--RGKTIKAQKLWYSILEAQTETGTPFVV 405 FSP+ PGL D + +EFE LYT+YEK+ R + +KA +L+ +++ + TG ++ Sbjct: 356 FSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQ 415 Query: 406 YKDACNRKSN-QKNLGVIKSSNLCCEIVEYSAP--------DETAVCNLASVALPAFIET 456 D CN S + ++ SNLC I + P E A+C L++ L A Sbjct: 416 NVDHCNTHSPFDPAIAPVRQSNLCLAIALPTKPLNDVNDENGEIALCTLSAFNLGAI--- 472 Query: 457 SEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTF 516 N +L E+A + R L+ ++D YP+ A++ M R + +GV A Sbjct: 473 --------NNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYL 524 Query: 517 MLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWD 576 + A L + FE I + ++AS ELA++ G F + ++GIL D + Sbjct: 525 AKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYK 584 Query: 577 Q-------KPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMY 629 + +P +DW+ LR+ I HG+RNS A MP+ ++SQI EP Sbjct: 585 KDLDTIANEPL-HYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPP----- 638 Query: 630 SRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWE 689 R V + +G+ + Q +P+ + L D Y+ +WE Sbjct: 639 -----------------RGYVSIKASKDGILR---------QVVPDY-EHLHDAYELLWE 671 Query: 690 I-SQKTIINMAADRSVYIDQSHSLNLFL---RAPT----MGKLTSMHFYGWKKGLKTGMY 741 + + + +IDQS S N R P+ M +L +K G+KT +Y Sbjct: 672 MPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKT-LY 730 Query: 742 YLRTQAASAAIQFTIDQKIADQATENVA 769 Y T+ + Q + I D E+ A Sbjct: 731 YQNTRDGAEDAQDDLVPSIQDDGCESGA 758 >6DQW-A nrPDB Length = 585 Score = 201 bits (511), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 173/612 (28%), Positives = 279/612 (45%), Gaps = 96/612 (15%) Query: 149 KTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAAL-ETY-NLMSLKYFTHASPTLF 206 + L R YLL+ E + I R+ R + L E++ ++ + + +SP Sbjct: 50 QILNRGYLLK-----GETVEGAIDRICTAAARRLYKPELKESFVEMIERGWMSISSPVWA 104 Query: 207 NAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTN 266 N GT + SCF V + D IEGI L E + +K GG + +R GS + N Sbjct: 105 NMGTERGLPISCFNVHVP-DKIEGITHKLGEVIMQTKIGGGTSGYFGELRERGSAVT-DN 162 Query: 267 GTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRAR 326 G S+G + +++F+ + QGG +R GAFA YL+ H DI +F+ I K+ G + Sbjct: 163 GKSSGAVSFMKLFDTAMDTISQGGVRR-GAFAAYLDIDHPDIEEFLKI-KSIGNP---IQ 217 Query: 327 DLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTIKAQ 386 +LF + +PD +M+ + + GD + Sbjct: 218 NLFTGICVPDYWMQEMID-------------------GD-----------------ADKR 241 Query: 387 KLWYSILEAQTETGTPFVVYKDACNRKSNQ----KNLGVIKSSNLCCEIVEYSAPDETAV 442 ++W +LE++ + G P++ + D N+ Q +NL I +SNLC EI+ S DE+ + Sbjct: 242 QIWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDESFI 300 Query: 443 CNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRH 502 C L+S+ L + E + F V + + NYY + A K RH Sbjct: 301 CCLSSMNLELYEEWKDTEAVKLAIF-----FLDAVLQEFIEKTEGNYY-LSAANKFAKRH 354 Query: 503 RPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQG 562 R + LGV G +PF+ EA++ +IF+ I + +AS ELA+ G E +G Sbjct: 355 RALGLGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELARIYGEPELLKG 414 Query: 563 SPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNE-CF 621 +G RN+ TMA PT S+S ILG Sbjct: 415 --------------------------------YGRRNTTTMAIAPTTSSSAILGQTSPGI 442 Query: 622 EPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELK 681 EP +SN Y + G F N YL + L + G+ +E + + ++ GS+Q + + Q+ K Sbjct: 443 EPFSSNYYKAGLSKGNFMRKNKYLKKLLEEKGLDNEEVWRGIMLNGGSVQHMSQLTQQEK 502 Query: 682 DLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGK-LTSMHFYGWKKGLKTGM 740 D++KT EISQ I+ A R ++DQ SLNL + A K + + W++G+K+ + Sbjct: 503 DVFKTFKEISQLEIVQQAGIRQKFVDQGQSLNLNIPAELAIKDVNRLMIEAWQQGVKS-L 561 Query: 741 YYLRTQAASAAI 752 YY R+Q+ S + Sbjct: 562 YYQRSQSVSKEL 573 >6DQX-A nrPDB Length = 574 Score = 182 bits (461), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 176/618 (28%), Positives = 274/618 (44%), Gaps = 118/618 (19%) Query: 151 LERSYLL-------RINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASP 203 L+R YLL RI +AE +H LGI G A + Y+ M+ YF+ +SP Sbjct: 41 LQRGYLLEGTTALERIRF-IAEHAEH-----KLGIEGY----ADKFYHYMARGYFSLSSP 90 Query: 204 TLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIA 263 N G + SCF + DSI I T E ++SK GG + +IR GS I Sbjct: 91 IWSNFGLDRGLPISCFGSYIG-DSIHEIMVTTAEVGMMSKIGGGTSAYFGDIRPRGSAIK 149 Query: 264 GTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEI 323 NG S+G ++F+ + QG R G FA Y++ H DI +++DI Sbjct: 150 -NNGKSDGSFNFSKLFDTVIDVISQG-TSRKGQFAGYIDIEHGDIDEWLDIH-------- 199 Query: 324 RARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTI 383 T +P C G ++ E G Sbjct: 200 -------------------------TEGNPIQLMYYGVCVGHDW------LESMKAGDPY 228 Query: 384 KAQKLWYSILEAQTETGTPFVVYKDACNRKS----NQKNLGVIKSSNLCCEIVEYSAPDE 439 K Q LW +L+ +TETG P++ +KD N KN+ + +SNLC EI+ S+ DE Sbjct: 229 KRQ-LWAKLLQRKTETGIPYLFFKDNANAGRPDVYKDKNM-TVHASNLCTEIMLPSSNDE 286 Query: 440 TAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVID------RNYYPVE 493 + VC L+S+ L F E + E +V+T L+ V+ ++ ++ Sbjct: 287 SFVCCLSSMNLLYFDEWKDT------------EAPEVLTYFLDVVMSEFIEKSKDMPFLD 334 Query: 494 EARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQK 553 A + RHR + LGV G + FDS +A N IF+T+ +++AS ELA++ Sbjct: 335 RAHRFATRHRALGLGVLGWHSYLQANNIAFDSFQAMQKNNLIFKTLQEKTLKASQELAKR 394 Query: 554 DGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQ 613 G E +G +G RN+ M+ PT S+S Sbjct: 395 FGEPEILKG--------------------------------YGRRNTTLMSIAPTKSSSF 422 Query: 614 ILG-YNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQG 672 ILG + EP SN Y + + + NP+L + L + G+ E + + ++ +GS+Q Sbjct: 423 ILGSVSPSVEPFKSNYYVKDLAKIKTVYKNPFLEKLLQEKGLDTEEIWESILHNDGSVQH 482 Query: 673 LPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGK-LTSMHFYG 731 L + E K+++KT EISQ ++I AA R YIDQ S+N+ + T + L ++ Sbjct: 483 LEQLTDEEKEVFKTFSEISQLSVIQQAAQRQKYIDQGQSINIMVHPATPARDLNQLYLTA 542 Query: 732 WKKGLKTGMYYLRTQAAS 749 + GLK+ +YY + +A+ Sbjct: 543 EELGLKS-IYYQYSMSAA 559 >6CGM-A nrPDB Length = 700 Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 164/654 (25%), Positives = 285/654 (43%), Gaps = 94/654 (14%) Query: 137 YDRDFQYSYF--GFKTLERSYLLRINGQ--VAERPQHLIMRVALGIHGRDIEAALETYNL 192 Y + F++ F FK Y L+ N + + ER + I VAL D E A E NL Sbjct: 85 YAKKFRFPSFMSAFK-FYNDYALKTNDKKKILERYEDRISIVALFFANGDTEKAKEYVNL 143 Query: 193 MSLKYFTHASPTLFNAGTPKP-QMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLH 251 M + + ++PT NAG + ++ SCFL+ + DS+ I + +SK GG+ L+ Sbjct: 144 MINQEYQPSTPTFLNAGRKRRGELVSCFLLEVN-DSLNDISRAIDISMQLSKLGGGVSLN 202 Query: 252 IHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDF 311 + +R+ G I + G++ ++++ +N RY DQ G +R G+ A YL +H DI DF Sbjct: 203 LSKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMG-QRQGSGAAYLNIFHRDINDF 261 Query: 312 IDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEA-- 369 +D +K E++R + L + IPD F++ E+ +F P + + DE + Sbjct: 262 LDTKKISADEDVRVKTLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMDEMDMNE 321 Query: 370 LYTRYEKEGRGKT--IKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNL 427 +Y ++ R K I +KL + ++E+G P+++++D N+ ++ +K SNL Sbjct: 322 MYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVKFSNL 381 Query: 428 CCEIVE---------YSAPDETAV---CNLASVALPAFIETSEDGKTSTYNFKKLHEIAK 475 C E+++ Y DE + CNL S+ + +E K + + K Sbjct: 382 CSEVLQASQVSSYTDYDEEDEIGLDISCNLGSLNILNVMEH-----------KSIEKTVK 430 Query: 476 VVTRNLNRVID----RNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLL 531 + T +L V + RN V R++N + I LG L + ++S EAR Sbjct: 431 LATDSLTHVSETTDIRNAPAV---RRANKAMKSIGLGAMNLHGYLAQNGIAYESPEARDF 487 Query: 532 NIQIFETIYHASMEASCELAQKDGP-YETFQGSPASQGILQFDMWDQKPY---------- 580 F + S++ S E+A++ G ++ ++GS + G FD + + Sbjct: 488 ANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYATGEY-FDKYVSTDFSPKYEKIANL 546 Query: 581 --GMW-----DWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRV 633 GM DW L+ + +HG+ +S + PT S S + P+ + R Sbjct: 547 FEGMHIPTTEDWKKLKAFVAEHGMYHSYRLCIAPTGSISYVQSSTASVMPIMERIEERTY 606 Query: 634 LSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQK 693 G + P +P + YK +++ Sbjct: 607 --GNSKTYYP-----------------------------MPGLASNNWFFYKEAYDMDMF 635 Query: 694 TIINMAADRSVYIDQSHSLNLFLR-APTMGKLTSMHFYGWKKGLKTGMYYLRTQ 746 +++M A +IDQ S LFL+ T L + Y +G+KT +YY RT+ Sbjct: 636 KVVDMIATIQQHIDQGISFTLFLKDTMTTRDLNRIDLYAHHRGIKT-IYYARTK 688 >1PEQ-A nrPDB Length = 714 Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 159/619 (25%), Positives = 260/619 (42%), Gaps = 98/619 (15%) Query: 171 IMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTP-KPQMSSCFLVAMKEDSIE 229 + VAL + D A + + M F A+PT N G + ++ SCFL+ + ED++E Sbjct: 130 VTMVALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFLLRI-EDNME 188 Query: 230 GIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQG 289 I + +SK GG+ + N+R G+ I S+G+IP++++ + Y +Q Sbjct: 189 SIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQL 248 Query: 290 GNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWT 349 G R GA A+YL H DI F+D ++ + E+IR + L + IPD+ + +EN Sbjct: 249 G-ARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFRLAKENAQMA 307 Query: 350 LFSPTSAPGLSDCYGDEFE--ALYTRYEK-----EGRGKTIKAQKLWYSILEAQTETGTP 402 LFSP + YG F A+ RY++ R I A+ + ++ E Q E+G P Sbjct: 308 LFSPYD---IQRRYGKPFGDIAISERYDELIADPHVRKTYINARDFFQTLAEIQFESGYP 364 Query: 403 FVVYKDACNRKSNQKNLGVIKSSNLCCEIVE------------YSAPDETAVCNLASVAL 450 +++++D NR + G I SNLC EI++ Y+ CNL S+ + Sbjct: 365 YIMFEDTVNRANPIA--GRINMSNLCSEILQVNSASRYDDNLDYTHIGHDISCNLGSLNI 422 Query: 451 PAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYY-PVEEARKSNMRHRPIALGV 509 +++ + G+T + R L V D ++ V N I LG Sbjct: 423 AHVMDSPDIGRT-----------VETAIRGLTAVSDMSHIRSVPSIAAGNAASHAIGLGQ 471 Query: 510 QGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGI 569 L + + S EA F TI ++ S LA++ G +TF G S+ Sbjct: 472 MNLHGYLAREGIAYGSPEALDFTNLYFYTITWHAVHTSMRLARERG--KTFAGFAQSR-Y 528 Query: 570 LQFDMWDQKPYGMWD----------------------WDTLRKDIMKHGVRNSLTMAPMP 607 D + Q W W LR D+M++G+ N A P Sbjct: 529 ASGDYFTQYLQDDWQPKTAKVRALFARSGITLPTREMWLKLRDDVMRYGIYNQNLQAVPP 588 Query: 608 TASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQN 667 T S S I P+ + + R+ EG + Sbjct: 589 TGSISYINHATSSIHPIVAKIEIRK------------------------EG-------KT 617 Query: 668 GSI-QGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFL-RAPTMGKLT 725 G + P + E D+Y+ ++I + II+ A+ + ++DQ SL LF T + Sbjct: 618 GRVYYPAPFMTNENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDIN 677 Query: 726 SMHFYGWKKGLKTGMYYLR 744 Y W+KG+K+ +YY+R Sbjct: 678 KAQIYAWRKGIKS-LYYIR 695 >3O0O-A nrPDB Length = 644 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 156/610 (25%), Positives = 267/610 (43%), Gaps = 91/610 (14%) Query: 190 YNLMSLKYFTHASPTLFNAG---------TPKPQM------------------SSCFLVA 222 + ++ + F SPTLFNAG P QM S+CF+V Sbjct: 79 FRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVP 138 Query: 223 MKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNT 282 + DSIE I++ +KE ALI+K GG+G + +R GS++AGT+G ++G + + VFN+ Sbjct: 139 VG-DSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSA 197 Query: 283 ARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRK-NHGKEEIRARDL---FPALWIPDLF 338 V QG +R GA L H DI +FID +K N G+ + +L FP Sbjct: 198 ISVVKQGSRRR-GALMGILNINHPDIEEFIDAKKENTGEAVLNFFNLSVGFPM--DKKEI 254 Query: 339 MKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTE 398 +K EE+G L P S K +K ++L+ I + Sbjct: 255 LKLYEEDGELELSHPRSTIR----------------------KKVKIRELFRKIATNAWK 292 Query: 399 TGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSE 458 +G P + + N+ I S+N C EI + CNL S+ + F Sbjct: 293 SGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEI----GLSDYEACNLGSIDVAKFY---- 344 Query: 459 DGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFML 518 + + L E+ ++ R L+ VID N +P+++ K+ R + LG+ G AD Sbjct: 345 --NNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYK 402 Query: 519 LRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGS--PASQGILQFDMWD 576 L +P++S+EAR + I + S EL ++ G + + S + F M Sbjct: 403 LEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAM-- 460 Query: 577 QKPYGMWDWDTLRKDIM---KHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRV 633 GM ++D +++M K RN + PT S S I + EP Y+R V Sbjct: 461 ----GMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFV 516 Query: 634 LSGEFQVVNPYL-----LRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVW 688 + E P L LR+ ++ I K+ + + GS++ +P+VP+++K ++ Sbjct: 517 -TKEDGTKEPLLYVNQVLREKLNPEILKRIEKE--LIEKGSLKDIPDVPEKIKKVFVVAL 573 Query: 689 EISQKTIINMAADRSVYIDQSHSLNLFL-RAPTMGKLTSMHFYGWKKGLKTGMYY----L 743 +I + M Y+D + S + + ++ T+ + +++ + ++ Y L Sbjct: 574 DIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSL 633 Query: 744 RTQAASAAIQ 753 +TQ + A++ Sbjct: 634 QTQVLTKALK 643 >2G3Y-A nrPDB Length = 211 Score = 33.1 bits (74), Expect = 0.54, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 16/85 (18%) Query: 499 NMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYE 558 N +R + +G QG+ + + IF + H SM++ CE+ +D Sbjct: 35 NTYYRVVLIGEQGVGKSTLA---------------NIFAGV-HDSMDSDCEVLGEDTYER 78 Query: 559 TFQGSPASQGILQFDMWDQKPYGMW 583 T S I+ DMW+ K W Sbjct: 79 TLMVDGESATIILLDMWENKGENEW 103 >6F74-A nrPDB Length = 598 Score = 32.3 bits (72), Expect = 0.83, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%) Query: 426 NLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVI 485 N+ C V+Y+A + C L S+ A ++ + T T NF K H I V + + ++ Sbjct: 103 NITCAPVDYAAGETPTSCILGSLPYYAVNASTREDITLTLNFAKQHNIRLVTSSTGHDLL 162 Query: 486 DRN 488 R+ Sbjct: 163 GRS 165 >2CJW-A nrPDB Length = 192 Score = 32.3 bits (72), Expect = 0.87, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 20/43 (46%) Query: 541 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMW 583 H SM++ CE+ +D T S I+ DMW+ K W Sbjct: 30 HDSMDSDCEVLGEDTYERTLMVDGESATIILLDMWENKGENEW 72 >3W4R-A nrPDB Length = 554 Score = 32.3 bits (72), Expect = 1.0, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 767 NVADISNLKRPSYMPSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLT 826 N RP PS S D +P T+ ++S+ + + P P + SL Sbjct: 409 NTTPTPEWARPPSTPSDPS--EGDPIPTTTTSKPATSKPSTTSQPATTSRPEPKPTTSLP 466 Query: 827 KGMAELNVQESKVEVPEVPAPTKNE 851 + E + + PEV P +NE Sbjct: 467 TPAPTASTTEEEAQQPEVELPAENE 491 >3P8T-A nrPDB Length = 294 Score = 31.2 bits (69), Expect = 2.4, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 305 HADIFDFIDIRKNHGKEEIRARDLFPALW---IPDLFMKRVEENGTW 348 H ++D+ DI + G +E + ++ W IP F R EENG W Sbjct: 157 HFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDR-EENGVW 202 >6G2J-O nrPDB Length = 355 Score = 30.0 bits (66), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 468 KKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQ 510 KKLHE ++V+T + N +N E A++ M+H P A G+Q Sbjct: 51 KKLHEYSRVITVDGNICSGKNKLAKEIAQQLGMKHYPEA-GIQ 92 >4N14-A nrPDB Length = 314 Score = 29.6 bits (65), Expect = 5.9, Method: Compositional matrix adjust. Identities = 47/187 (25%), Positives = 75/187 (40%), Gaps = 12/187 (6%) Query: 675 NVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNL--FLRAPTMGKLTSMHFYGW 732 + P+ D Y + + S ++ +A D SVY+ + S ++ L+ G+ S + Sbjct: 14 DAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAW-- 71 Query: 733 KKGLKTGMYYLRTQAASAAIQF--TIDQKIADQATENVADISNLKRPSYMPSSASYAASD 790 +K G YL +SA +Q QK T + A + +L SY+ SS S + Sbjct: 72 ---IKEGN-YLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHI 127 Query: 791 FVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAEL-NVQESK-VEVPEVPAPT 848 A + +L S+ AP G H + G L NV S E VP T Sbjct: 128 HHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQT 187 Query: 849 KNEEKAA 855 + + A Sbjct: 188 FTQHQGA 194 >4V89-AW nrPDB Length = 534 Score = 29.6 bits (65), Expect = 6.5, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 7 DGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYE 49 D R DK T + ++ +DPKH D V R++SG YE Sbjct: 285 DTRTVEASEDKFTGFVFKIQANMDPKHRDRVAF-MRVVSGKYE 326 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2ZLF-A nrPDB 1366 0.0 5D1Y-A nrPDB 1081 0.0 2WGH-A nrPDB 971 0.0 5IM3-A nrPDB 903 0.0 5R1R-A nrPDB 785 0.0 6CGM-A nrPDB 578 e-165 6DQW-A nrPDB 569 e-162 1PEQ-A nrPDB 565 e-161 6DQX-A nrPDB 540 e-153 3O0O-A nrPDB 517 e-146 Sequences not found previously or not previously below threshold: 1L1L-A nrPDB 49 1e-05 3W4R-A nrPDB 38 0.015 2QZU-A nrPDB 38 0.021 4HZC-A nrPDB 38 0.023 2GAI-A nrPDB 36 0.061 5BO5-A nrPDB 35 0.14 6AF0-A nrPDB 33 0.77 2ZRW-A nrPDB 32 1.2 6CES-N nrPDB 32 1.3 3U27-C nrPDB 31 2.0 5NUH-A nrPDB 31 2.5 3IK5-A nrPDB 31 2.5 6DQU-A nrPDB 31 3.0 3CWV-A nrPDB 29 6.4 5FL8-r nrPDB 29 6.5 >2ZLF-A nrPDB Length = 888 Score = 1366 bits (3536), Expect = 0.0, Method: Composition-based stats. Identities = 888/888 (100%), Positives = 888/888 (100%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 Query: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 Query: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 Query: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 Query: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 Query: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 Query: 361 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG 420 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG Sbjct: 361 DCYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLG 420 Query: 421 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN 480 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN Sbjct: 421 VIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRN 480 Query: 481 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY 540 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY Sbjct: 481 LNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIY 540 Query: 541 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS 600 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS Sbjct: 541 HASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNS 600 Query: 601 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK 660 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK Sbjct: 601 LTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMK 660 Query: 661 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT 720 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT Sbjct: 661 QYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPT 720 Query: 721 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM 780 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM Sbjct: 721 MGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYM 780 Query: 781 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE 840 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE Sbjct: 781 PSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVE 840 Query: 841 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG 888 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG Sbjct: 841 VPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG 888 >5D1Y-A nrPDB Length = 812 Score = 1081 bits (2794), Expect = 0.0, Method: Composition-based stats. Identities = 507/760 (66%), Positives = 633/760 (83%), Gaps = 6/760 (0%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 M+V KRDGR+E V FDKIT+RI +LCYGL+ +D ++T ++I G+Y GVTT+ELD LA Sbjct: 21 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 80 Query: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 AET A +TT HPDYA LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ Sbjct: 81 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 140 Query: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 +IV+ NKD+LNSAI+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH Sbjct: 141 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 200 Query: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 DI+AA+ETYNL+S ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CAL Sbjct: 201 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 260 Query: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 ISK+AGGIG+ + IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+Y Sbjct: 261 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 320 Query: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 LEPWH DIF+F+D++KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL Sbjct: 321 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 380 Query: 361 DCYGDEFEALYTRYEKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419 + +G+EFE LY YEK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NL Sbjct: 381 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 440 Query: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTR 479 G IK SNLC EIVEY++ DE AVCNLAS+AL ++ + TY+FKKL E+ KVV R Sbjct: 441 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSE-----HTYDFKKLAEVTKVVVR 495 Query: 480 NLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETI 539 NLN++ID NYYPV EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETI Sbjct: 496 NLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETI 555 Query: 540 YHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRN 599 Y+ ++EASC+LA++ GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RN Sbjct: 556 YYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRN 615 Query: 600 SLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGM 659 SL +APMPTAST+QILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E M Sbjct: 616 SLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEM 675 Query: 660 KQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAP 719 K +I NGSIQ +P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P Sbjct: 676 KNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 735 Query: 720 TMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQK 759 GKLTSMHFYGWK+GLKTGMYYLRT+ A+ IQFT++++ Sbjct: 736 NYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKE 775 >2WGH-A nrPDB Length = 676 Score = 971 bits (2510), Expect = 0.0, Method: Composition-based stats. Identities = 458/674 (67%), Positives = 566/674 (83%), Gaps = 6/674 (0%) Query: 75 ATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSA 134 A LAARIA+SNLHK+T K FS V+EDLY Y+N GK +PM++ +IV+ NKD+LNSA Sbjct: 2 AILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSA 61 Query: 135 IVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMS 194 I+YDRDF Y+YFGFKTLERSYLL+ING+VAERPQH++MRV++GIH DI+AA+ETYNL+S Sbjct: 62 IIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLS 121 Query: 195 LKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHN 254 ++FTHASPTLFNAGT +PQ+SSCFL++MK+DSIEGIYDTLK+CALISK+AGGIG+ + Sbjct: 122 ERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSC 181 Query: 255 IRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDI 314 IR+TGSYIAGTNG SNGL+PM+RV+NNTARYVDQGGNKRPGAFA+YLEPWH DIF+F+D+ Sbjct: 182 IRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDL 241 Query: 315 RKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRY 374 +KN GKEE RARDLF ALWIPDLFMKRVE N W+L P PGL + +G+EFE LY Y Sbjct: 242 KKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASY 301 Query: 375 EKEGR-GKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVE 433 EK+GR K +KAQ+LWY+I+E+QTETGTP+++YKD+CNRKSNQ+NLG IK SNLC EIVE Sbjct: 302 EKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVE 361 Query: 434 YSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVE 493 Y++ DE AVCNLAS+AL ++ + TY+FKKL E+ KVV RNLN++ID NYYPV Sbjct: 362 YTSKDEVAVCNLASLALNMYVTSE-----HTYDFKKLAEVTKVVVRNLNKIIDINYYPVP 416 Query: 494 EARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQK 553 EA SN RHRPI +GVQGLAD F+L+R PF+S EA+LLN QIFETIY+ ++EASC+LA++ Sbjct: 417 EACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKE 476 Query: 554 DGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQ 613 GPYET++GSP S+GILQ+DMW+ P +WDW L++ I K+G+RNSL +APMPTAST+Q Sbjct: 477 QGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQ 536 Query: 614 ILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGL 673 ILG NE EP TSN+Y+RRVLSGEFQ+VNP+LL+DL + G+W E MK +I NGSIQ + Sbjct: 537 ILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSI 596 Query: 674 PNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWK 733 P +P +LK LYKTVWEISQKT++ MAA+R +IDQS SLN+ + P GKLTSMHFYGWK Sbjct: 597 PEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWK 656 Query: 734 KGLKTGMYYLRTQA 747 +GLKTGMYYLRT+A Sbjct: 657 QGLKTGMYYLRTRA 670 >5IM3-A nrPDB Length = 963 Score = 903 bits (2332), Expect = 0.0, Method: Composition-based stats. Identities = 304/784 (38%), Positives = 440/784 (56%), Gaps = 42/784 (5%) Query: 3 VYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAE 62 + + DG P+ ++ IS C GL +D + + + +Y+GV +++ Sbjct: 150 ITRADGSLSPLDMGRLNTIISEACEGL--AEVDGALIERETLKNLYDGVAEKDVNTALVM 207 Query: 63 TCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAA---TGKPAPMISDD 119 T + P+Y+ + AR+ + L + F V E + A PA + Sbjct: 208 TARTLVEREPNYSYVTARLLMDTLRAEALG-FLGVAESATHHEMAELYAKALPAYIEKGA 266 Query: 120 VYNIVME-----NKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRV 174 + +V + +KL AI ++RD Q++Y G +TL Y + +G E PQ MRV Sbjct: 267 EFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDRYFIHKDGIRFELPQIFFMRV 326 Query: 175 ALG--IHGRDIEA-ALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGI 231 A+G I +D EA A+E YNL+S + ++PTLFNAGT +PQ+SSC+L + +D + GI Sbjct: 327 AMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTLFNAGTLRPQLSSCYLTTVPDD-LSGI 385 Query: 232 YDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGN 291 Y + + A++SK AGG+G +R+ GSYI GTNG S G++P ++V N+TA V+QGG Sbjct: 386 YGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQGG- 444 Query: 292 KRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLF 351 KR GA YLE WH DI +F+++RKN G + R D+ A WIPDLFMKRV ++G+WTLF Sbjct: 445 KRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDGSWTLF 504 Query: 352 SPTSAPGLSDCYGDEFEALYTRYE------KEGRGKTIKAQKLWYSILEAQTETGTPFVV 405 SP+ P L D YG FE Y YE K K ++A+ LW +L ETG P++ Sbjct: 505 SPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHKVVQAKDLWRKMLSMLFETGHPWLT 564 Query: 406 YKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTY 465 +KD CN +S Q+++GV+ SSNLC EI + DE AVCNL S+ L I Sbjct: 565 FKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIV------DGKL 618 Query: 466 NFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDS 525 + KL + K R L+ VID NYY V +A+ SN +HRP+ LG+ G D L +P+ S Sbjct: 619 DTAKLEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLGIMGFQDALYLQHIPYGS 678 Query: 526 EEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFD------------ 573 + A Q E I + +++ASC+LA + G Y+TFQGS SQGIL D Sbjct: 679 DAAIAFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQGILPIDSEKKLIEERGAK 738 Query: 574 MWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRV 633 + DW LR+ + K G+RNS MA PTA+ + I G ++ EP N+Y + Sbjct: 739 YIEVDLSETLDWAPLRERVQK-GIRNSNIMAIAPTATIANITGVSQSIEPTYQNLYVKSN 797 Query: 634 LSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQK 693 LSGEF V+NPYL+RDL G+WD M L +GS+Q + +PQ+LKDLY T +E+ + Sbjct: 798 LSGEFTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDLYATAFEVETR 857 Query: 694 TIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQ 753 I+ A+ R +IDQ+ SLNL++ + KL + W +GLKT YYLR AA++ + Sbjct: 858 WIVEAASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGLKT-TYYLRALAATSTEK 916 Query: 754 FTID 757 TI+ Sbjct: 917 STIN 920 >5R1R-A nrPDB Length = 761 Score = 785 bits (2026), Expect = 0.0, Method: Composition-based stats. Identities = 219/807 (27%), Positives = 347/807 (42%), Gaps = 91/807 (11%) Query: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 + V KRDG E + DKI + GL I V++ I Y+G+ T ++ Sbjct: 5 LLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHI--QFYDGIKTSDIHETI 62 Query: 61 AETCAYMTTVH-PDYATLAARIAISNLHKQTTKQFSKVVEDLYRYV--NAATGKPAPMIS 117 + A + + PDY LAAR+AI +L K+ QF LY +V GK + Sbjct: 63 IKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPA--LYDHVVKMVEMGKYDNHLL 120 Query: 118 DDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLL--RINGQVAERPQHLIMRVA 175 +D E ++++ I +DRD +SY K LE YL+ R+ G++ E Q L + VA Sbjct: 121 EDY---TEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVA 177 Query: 176 LGIHGR-----DIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEG 230 + ++ Y+ +S + +P + TP Q SSC L+ DS++ Sbjct: 178 ACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECG-DSLDS 236 Query: 231 IYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGG 290 I T GIG++ IR+ GS I G G IP + F + QGG Sbjct: 237 INATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG 296 Query: 291 NKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTL 350 R GA L+ WH ++ + ++ N G E R R + + I L R+ + TL Sbjct: 297 V-RGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITL 355 Query: 351 FSPTSAPGLSDCY---GDEFEALYTRYEKEG--RGKTIKAQKLWYSILEAQTETGTPFVV 405 FSP+ PGL D + +EFE LYT+YEK+ R + +KA +L+ +++ + TG ++ Sbjct: 356 FSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQ 415 Query: 406 YKDACNRKSN-QKNLGVIKSSNLCCEIVEYSAP--------DETAVCNLASVALPAFIET 456 D CN S + ++ SNLC I + P E A+C L++ L A Sbjct: 416 NVDHCNTHSPFDPAIAPVRQSNLCLAIALPTKPLNDVNDENGEIALCTLSAFNLGAI--- 472 Query: 457 SEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTF 516 N +L E+A + R L+ ++D YP+ A++ M R + +GV A Sbjct: 473 --------NNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYL 524 Query: 517 MLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWD 576 + A L + FE I + ++AS ELA++ G F + ++GIL D + Sbjct: 525 AKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYK 584 Query: 577 QKPYG------MWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYS 630 + +DW+ LR+ I HG+RNS A MP+ ++SQI EP Sbjct: 585 KDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPP------ 638 Query: 631 RRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEI 690 R V + +G+ + Q +P+ + L D Y+ +WE+ Sbjct: 639 ----------------RGYVSIKASKDGILR---------QVVPDY-EHLHDAYELLWEM 672 Query: 691 -SQKTIINMAADRSVYIDQSHSLNLFLRAPT-------MGKLTSMHFYGWKKGLKTGMYY 742 + + +IDQS S N M +L +K G+KT +YY Sbjct: 673 PGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKT-LYY 731 Query: 743 LRTQAASAAIQFTIDQKIADQATENVA 769 T+ + Q + I D E+ A Sbjct: 732 QNTRDGAEDAQDDLVPSIQDDGCESGA 758 >6CGM-A nrPDB Length = 700 Score = 578 bits (1489), Expect = e-165, Method: Composition-based stats. Identities = 173/726 (23%), Positives = 301/726 (41%), Gaps = 110/726 (15%) Query: 86 LHKQTTKQFSKVVEDLY----RYVNAA-------TGKPAPMISDDVYNIVMENKDKLNSA 134 + K QF K E ++ Y+N K ++ + Y E L S Sbjct: 18 IQKDGKFQFDKDKEAVHSYFVDYINQNTVFFHNLKEKLDYLVENQYYE---EEFLSLYSF 74 Query: 135 IV--------YDRDFQYSYF--GFKTLERSYLLRINGQ--VAERPQHLIMRVALGIHGRD 182 Y + F++ F FK Y L+ N + + ER + I VAL D Sbjct: 75 EDIKEVFKTAYAKKFRFPSFMSAFK-FYNDYALKTNDKKKILERYEDRISIVALFFANGD 133 Query: 183 IEAALETYNLMSLKYFTHASPTLFNAGTPK-PQMSSCFLVAMKEDSIEGIYDTLKECALI 241 E A E NLM + + ++PT NAG + ++ SCFL+ + DS+ I + + Sbjct: 134 TEKAKEYVNLMINQEYQPSTPTFLNAGRKRRGELVSCFLLEVN-DSLNDISRAIDISMQL 192 Query: 242 SKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYL 301 SK GG+ L++ +R+ G I + G++ ++++ +N RY DQ G +R G+ A YL Sbjct: 193 SKLGGGVSLNLSKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMG-QRQGSGAAYL 251 Query: 302 EPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSD 361 +H DI DF+D +K E++R + L + IPD F++ E+ +F P + Sbjct: 252 NIFHRDINDFLDTKKISADEDVRVKTLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYG 311 Query: 362 CYGDEFEA--LYTRYEKEGRGK--TIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQK 417 + DE + +Y ++ R K I +KL + ++E+G P+++++D N+ Sbjct: 312 QHMDEMDMNEMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANN 371 Query: 418 NLGVIKSSNLCCEIVE---------YSAPDETAV---CNLASVALPAFIETSEDGKTSTY 465 ++ +K SNLC E+++ Y DE + CNL S+ + +E Sbjct: 372 HISKVKFSNLCSEVLQASQVSSYTDYDEEDEIGLDISCNLGSLNILNVMEH--------- 422 Query: 466 NFKKLHEIAKVVTRNLNRVIDRNYY-PVEEARKSNMRHRPIALGVQGLADTFMLLRLPFD 524 K + + K+ T +L V + R++N + I LG L + ++ Sbjct: 423 --KSIEKTVKLATDSLTHVSETTDIRNAPAVRRANKAMKSIGLGAMNLHGYLAQNGIAYE 480 Query: 525 SEEARLLNIQIFETIYHASMEASCELAQKDGP-YETFQGSPASQGILQFDMWDQKPY--- 580 S EAR F + S++ S E+A++ G ++ ++GS + G FD + + Sbjct: 481 SPEARDFANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYATGEY-FDKYVSTDFSPK 539 Query: 581 ---------GMW-----DWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTS 626 GM DW L+ + +HG+ +S + PT S S + P+ Sbjct: 540 YEKIANLFEGMHIPTTEDWKKLKAFVAEHGMYHSYRLCIAPTGSISYVQSSTASVMPIME 599 Query: 627 NMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKT 686 + R G + P +P + YK Sbjct: 600 RIEERTY--GNSKTYYP-----------------------------MPGLASNNWFFYKE 628 Query: 687 VWEISQKTIINMAADRSVYIDQSHSLNLFLR-APTMGKLTSMHFYGWKKGLKTGMYYLRT 745 +++ +++M A +IDQ S LFL+ T L + Y +G+KT +YY RT Sbjct: 629 AYDMDMFKVVDMIATIQQHIDQGISFTLFLKDTMTTRDLNRIDLYAHHRGIKT-IYYART 687 Query: 746 QAASAA 751 + Sbjct: 688 KDTGQD 693 >6DQW-A nrPDB Length = 585 Score = 569 bits (1467), Expect = e-162, Method: Composition-based stats. Identities = 168/627 (26%), Positives = 279/627 (44%), Gaps = 99/627 (15%) Query: 149 KTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALE--TYNLMSLKYFTHASPTLF 206 + L R YLL+ E + I R+ R + L+ ++ + + +SP Sbjct: 50 QILNRGYLLK-----GETVEGAIDRICTAAARRLYKPELKESFVEMIERGWMSISSPVWA 104 Query: 207 NAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTN 266 N GT + SCF V + D IEGI L E + +K GG + +R GS + N Sbjct: 105 NMGTERGLPISCFNVHVP-DKIEGITHKLGEVIMQTKIGGGTSGYFGELRERGSAVTD-N 162 Query: 267 GTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRAR 326 G S+G + +++F+ + QGG +R GAFA YL+ H DI +F+ I+ + Sbjct: 163 GKSSGAVSFMKLFDTAMDTISQGGVRR-GAFAAYLDIDHPDIEEFLKIKSI----GNPIQ 217 Query: 327 DLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTIKAQ 386 +LF + +PD +M+ + + + Sbjct: 218 NLFTGICVPDYWMQEMIDGDA------------------------------------DKR 241 Query: 387 KLWYSILEAQTETGTPFVVYKDACNRKSNQ----KNLGVIKSSNLCCEIVEYSAPDETAV 442 ++W +LE++ + G P++ + D N+ Q +NL I +SNLC EI+ S DE+ + Sbjct: 242 QIWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDESFI 300 Query: 443 CNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRH 502 C L+S+ L + E + F V + + NYY + A K RH Sbjct: 301 CCLSSMNLELYEEWKDTEAVKLAIF-----FLDAVLQEFIEKTEGNYY-LSAANKFAKRH 354 Query: 503 RPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQG 562 R + LGV G +PF+ EA++ +IF+ I + +AS ELA+ G E +G Sbjct: 355 RALGLGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELARIYGEPELLKG 414 Query: 563 SPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNE-CF 621 +G RN+ TMA PT S+S ILG Sbjct: 415 --------------------------------YGRRNTTTMAIAPTTSSSAILGQTSPGI 442 Query: 622 EPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELK 681 EP +SN Y + G F N YL + L + G+ +E + + ++ GS+Q + + Q+ K Sbjct: 443 EPFSSNYYKAGLSKGNFMRKNKYLKKLLEEKGLDNEEVWRGIMLNGGSVQHMSQLTQQEK 502 Query: 682 DLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTM-GKLTSMHFYGWKKGLKTGM 740 D++KT EISQ I+ A R ++DQ SLNL + A + + W++G+K+ + Sbjct: 503 DVFKTFKEISQLEIVQQAGIRQKFVDQGQSLNLNIPAELAIKDVNRLMIEAWQQGVKS-L 561 Query: 741 YYLRTQAASAAIQFTIDQKIADQATEN 767 YY R+Q+ S + ++ ++ + E+ Sbjct: 562 YYQRSQSVSKELVTSL---VSCSSCES 585 >1PEQ-A nrPDB Length = 714 Score = 565 bits (1455), Expect = e-161, Method: Composition-based stats. Identities = 165/660 (25%), Positives = 275/660 (41%), Gaps = 99/660 (15%) Query: 137 YDRDFQY-SYFGFKTLERSYLLRI-NGQVA-ERPQHLIMRVALGIHGRDIEAALETYNLM 193 + F++ ++ G SY L+ +G+ E + + VAL + D A + + M Sbjct: 93 HASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEHFEDRVTMVALTLAQGDETLATQLTDEM 152 Query: 194 SLKYFTHASPTLFNAGTP-KPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHI 252 F A+PT N G + ++ SCFL+ + ED++E I + +SK GG+ + Sbjct: 153 LSGRFQPATPTFLNCGKQQRGELVSCFLLRI-EDNMESIGRAVNSALQLSKRGGGVAFLL 211 Query: 253 HNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFI 312 N+R G+ I S+G+IP++++ + Y +Q G R GA A+YL H DI F+ Sbjct: 212 SNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLG-ARQGAGAVYLHAHHPDILRFL 270 Query: 313 DIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFE--AL 370 D ++ + E+IR + L + IPD+ + +EN LFSP YG F A+ Sbjct: 271 DTKRENADEKIRIKTLSLGVVIPDITFRLAKENAQMALFSPYDI---QRRYGKPFGDIAI 327 Query: 371 YTRYEK-----EGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSS 425 RY++ R I A+ + ++ E Q E+G P+++++D NR + G I S Sbjct: 328 SERYDELIADPHVRKTYINARDFFQTLAEIQFESGYPYIMFEDTVNRANPIA--GRINMS 385 Query: 426 NLCCEIVE------------YSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEI 473 NLC EI++ Y+ CNL S+ + +++ + G+T Sbjct: 386 NLCSEILQVNSASRYDDNLDYTHIGHDISCNLGSLNIAHVMDSPDIGRT----------- 434 Query: 474 AKVVTRNLNRVIDRNYY-PVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLN 532 + R L V D ++ V N I LG L + + S EA Sbjct: 435 VETAIRGLTAVSDMSHIRSVPSIAAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFT 494 Query: 533 IQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWD-------- 584 F TI ++ S LA++ G +TF G S+ D + Q W Sbjct: 495 NLYFYTITWHAVHTSMRLARERG--KTFAGFAQSR-YASGDYFTQYLQDDWQPKTAKVRA 551 Query: 585 --------------WDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYS 630 W LR D+M++G+ N A PT S S I P+ + + Sbjct: 552 LFARSGITLPTREMWLKLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKIEI 611 Query: 631 RRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEI 690 R+ G+ V P + E D+Y+ ++I Sbjct: 612 RK--EGKTGRVY----------------------------YPAPFMTNENLDMYQDAYDI 641 Query: 691 SQKTIINMAADRSVYIDQSHSLNLFLR-APTMGKLTSMHFYGWKKGLKTGMYYLRTQAAS 749 + II+ A+ + ++DQ SL LF T + Y W+KG+K+ +YY+R + + Sbjct: 642 GPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKS-LYYIRLRQLA 700 >6DQX-A nrPDB Length = 574 Score = 540 bits (1391), Expect = e-153, Method: Composition-based stats. Identities = 175/619 (28%), Positives = 274/619 (44%), Gaps = 118/619 (19%) Query: 151 LERSYLL-------RINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASP 203 L+R YLL RI +AE +H LGI G A + Y+ M+ YF+ +SP Sbjct: 41 LQRGYLLEGTTALERIRF-IAEHAEH-----KLGIEG----YADKFYHYMARGYFSLSSP 90 Query: 204 TLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIA 263 N G + SCF + DSI I T E ++SK GG + +IR GS I Sbjct: 91 IWSNFGLDRGLPISCFGSYIG-DSIHEIMVTTAEVGMMSKIGGGTSAYFGDIRPRGSAIK 149 Query: 264 GTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEI 323 NG S+G ++F+ + Q G R G FA Y++ H DI +++DI Sbjct: 150 -NNGKSDGSFNFSKLFDTVIDVISQ-GTSRKGQFAGYIDIEHGDIDEWLDIH-------- 199 Query: 324 RARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTI 383 T +P C G ++ E G Sbjct: 200 -------------------------TEGNPIQLMYYGVCVGHDW------LESMKAGDPY 228 Query: 384 KAQKLWYSILEAQTETGTPFVVYKDACNRKSNQ----KNLGVIKSSNLCCEIVEYSAPDE 439 K ++LW +L+ +TETG P++ +KD N KN+ + +SNLC EI+ S+ DE Sbjct: 229 K-RQLWAKLLQRKTETGIPYLFFKDNANAGRPDVYKDKNM-TVHASNLCTEIMLPSSNDE 286 Query: 440 TAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVID------RNYYPVE 493 + VC L+S+ L F E + E +V+T L+ V+ ++ ++ Sbjct: 287 SFVCCLSSMNLLYFDEWKDT------------EAPEVLTYFLDVVMSEFIEKSKDMPFLD 334 Query: 494 EARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQK 553 A + RHR + LGV G + FDS +A N IF+T+ +++AS ELA++ Sbjct: 335 RAHRFATRHRALGLGVLGWHSYLQANNIAFDSFQAMQKNNLIFKTLQEKTLKASQELAKR 394 Query: 554 DGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQ 613 G E +G +G RN+ M+ PT S+S Sbjct: 395 FGEPEILKG--------------------------------YGRRNTTLMSIAPTKSSSF 422 Query: 614 ILG-YNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQG 672 ILG + EP SN Y + + + NP+L + L + G+ E + + ++ +GS+Q Sbjct: 423 ILGSVSPSVEPFKSNYYVKDLAKIKTVYKNPFLEKLLQEKGLDTEEIWESILHNDGSVQH 482 Query: 673 LPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTM-GKLTSMHFYG 731 L + E K+++KT EISQ ++I AA R YIDQ S+N+ + T L ++ Sbjct: 483 LEQLTDEEKEVFKTFSEISQLSVIQQAAQRQKYIDQGQSINIMVHPATPARDLNQLYLTA 542 Query: 732 WKKGLKTGMYYLRTQAASA 750 + GLK+ +YY + +A+ Sbjct: 543 EELGLKS-IYYQYSMSAAQ 560 >3O0O-A nrPDB Length = 644 Score = 517 bits (1330), Expect = e-146, Method: Composition-based stats. Identities = 156/617 (25%), Positives = 266/617 (43%), Gaps = 87/617 (14%) Query: 181 RDIEAALETYNLMSLKYFTHASPTLFNAG---------TPKPQM---------------- 215 R E + ++ + F SPTLFNAG P QM Sbjct: 70 RIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLH 129 Query: 216 --SSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLI 273 S+CF+V + DSIE I++ +KE ALI+K GG+G + +R GS++AGT+G ++G + Sbjct: 130 MLSACFVVPVG-DSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPV 188 Query: 274 PMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRK-NHGKEEIRARDLFPAL 332 + VFN+ V QG +R GA L H DI +FID +K N G+ + +L Sbjct: 189 SFMHVFNSAISVVKQGSRRR-GALMGILNINHPDIEEFIDAKKENTGEAVLNFFNLSVGF 247 Query: 333 -WIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRGKTIKAQKLWYS 391 +K EE+G L P S K +K ++L+ Sbjct: 248 PMDKKEILKLYEEDGELELSHPRSTI----------------------RKKVKIRELFRK 285 Query: 392 ILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALP 451 I ++G P + + N+ I S+N C EI + CNL S+ + Sbjct: 286 IATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEI----GLSDYEACNLGSIDVA 341 Query: 452 AFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQG 511 F + + L E+ ++ R L+ VID N +P+++ K+ R + LG+ G Sbjct: 342 KFY------NNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMG 395 Query: 512 LADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPA--SQGI 569 AD L +P++S+EAR + I + S EL ++ G + + S Sbjct: 396 FADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNF 455 Query: 570 LQFDMWDQKPYGMWDWDTLRKDIM---KHGVRNSLTMAPMPTASTSQILGYNECFEPVTS 626 + F M GM ++D +++M K RN + PT S S I + EP Sbjct: 456 VPFAM------GMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFL 509 Query: 627 NMYSRRVLSGEFQVVNPYL-----LRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELK 681 Y+R V + E P L LR+ ++ I K+ + + GS++ +P+VP+++K Sbjct: 510 LAYTRFV-TKEDGTKEPLLYVNQVLREKLNPEILKRIEKE--LIEKGSLKDIPDVPEKIK 566 Query: 682 DLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLR-APTMGKLTSMHFYGWKKGLKTGM 740 ++ +I + M Y+D + S + + + T+ + +++ + ++ Sbjct: 567 KVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGIT 626 Query: 741 YY----LRTQAASAAIQ 753 Y L+TQ + A++ Sbjct: 627 VYRDGSLQTQVLTKALK 643 >1L1L-A nrPDB Length = 739 Score = 49.1 bits (115), Expect = 1e-05, Method: Composition-based stats. Identities = 76/490 (15%), Positives = 148/490 (30%), Gaps = 85/490 (17%) Query: 250 LHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIF 309 L + +IR G+ I G GT++G +P+I + + ++ NK G ADI Sbjct: 252 LDLSDIRPYGAEIHGFGGTASGPMPLISMLLDVNEVLN---NKAGGRLTA---VDAADIC 305 Query: 310 DFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEA 369 + I + R+ +L F+ ++ Sbjct: 306 NLIG-KAVVAGNVRRSAELALGSNDDQDFISMKQDQEKL--------------------- 343 Query: 370 LYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKN------LGVIK 423 ++ R+ A + I E G P +V D + G ++ Sbjct: 344 MHHRWASNNSVAVDSAFSGYQPIAAGIRENGEPGIVNLDLSKNYGRIVDGYQAGIDGDVE 403 Query: 424 SSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNR 483 +N C EI + CNL F + ++ L E+ + R R Sbjct: 404 GTNPCGEISLANGEP----CNL-------FEVFPLIAEEQGWD---LQEVFALAARYAKR 449 Query: 484 VIDRNYYPVEEARKSNMRHRPIALGVQGLADTFM-LLRLPFDSEEARLLNIQIFETIYHA 542 V + Y E +R+ ++R I + + G+ D + L + + + E I Sbjct: 450 VT-FSPYDWEISREIIQKNRRIGISMSGIQDWLLTRLGNRVVTGFKDDFDPETHEAI--- 505 Query: 543 SMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLT 602 + + + + I Sbjct: 506 -------------KVPVYDKRAIKMVDQLYKAVVKADQDYSKTLGCNESIKH-------- 544 Query: 603 MAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQY 662 P+ + +++ G +E +R+ FQ +P LL L G E Sbjct: 545 TTVKPSGTVAKLAGASEGMHFHYGAYLIQRI---RFQDSDP-LLPALKACGYRTEA---D 597 Query: 663 LITQNGSIQGLP--NVPQELKDLYKTVWEISQKTIINMAADRSVY-IDQSHSLNLFLRAP 719 + T+N + P V + + + + +S A Y D + S + + Sbjct: 598 IYTENTTCVEFPIKAVGADNPN-FASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQDS 656 Query: 720 TMGKLTSMHF 729 ++ S+ Sbjct: 657 EGDQVESLLR 666 >3W4R-A nrPDB Length = 554 Score = 38.3 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 2/76 (2%) Query: 776 RPSYMPSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQ 835 RP PS S D +P T+ ++S+ + + P P + SL + Sbjct: 418 RPPSTPSDPS--EGDPIPTTTTSKPATSKPSTTSQPATTSRPEPKPTTSLPTPAPTASTT 475 Query: 836 ESKVEVPEVPAPTKNE 851 E + + PEV P +NE Sbjct: 476 EEEAQQPEVELPAENE 491 >2QZU-A nrPDB Length = 491 Score = 37.9 bits (86), Expect = 0.021, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 52/160 (32%), Gaps = 12/160 (7%) Query: 249 GLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADI 308 G+ + + GS + G + + + N + D K G Y+ WH D Sbjct: 81 GMLMTGMYPIGSKVTGNCNSETAPYGV-ELSQNARCWSDVL--KDQGYNMGYIGKWHLDA 137 Query: 309 --FDFIDIRKNHGKEEIRA-----RDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSD 361 ++D N GK R WI + W +P + + Sbjct: 138 PYKPYVDTYNNRGKVAWNEWCPPERRHGFDHWIAYGTYDYHLKPMYWNTTAPRDSFYYVN 197 Query: 362 CYGDEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGT 401 +G E+EA ++ + G+ + Q + TG Sbjct: 198 QWGPEYEA--SKAIEYINGQKDQKQPFALVVSMNPPHTGY 235 >4HZC-A nrPDB Length = 281 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 27/156 (17%), Positives = 63/156 (40%), Gaps = 11/156 (7%) Query: 611 TSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSI 670 +S++ + +P+ ++ R + E +P L L + +++ ++ + Sbjct: 6 SSKVNAGLDQVDPIWHSI---RAEAEEATRNDPVLGAFLYATILNQPSLEEAVMHRIAER 62 Query: 671 QGLPNVPQE-LKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGK---LTS 726 G P+V + L+ + T+ E + + + D D+ + + F+ K Sbjct: 63 LGHPDVSADILRQTFDTMLEANPEWSHVLRVDIQAVYDRDPAYSRFMDPVLYLKGFHAIQ 122 Query: 727 MHFYG---WKKGLKTGMYYLRTQAASAAIQFTIDQK 759 H +K+G K YYL++++ S+ Q I Sbjct: 123 THRLAHWLYKQGRKDFAYYLQSRS-SSIFQTDIHPA 157 >2GAI-A nrPDB Length = 633 Score = 36.4 bits (82), Expect = 0.061, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 36/103 (34%), Gaps = 10/103 (9%) Query: 40 TQRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTT-------K 92 T I +YEGV T + +T DYA AR I+ + + + Sbjct: 265 TMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERR 324 Query: 93 QFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSAI 135 + + ++D + + P + N ++ KL I Sbjct: 325 KSNAKIQDAHEAIRPTNVFMTPEEAGKYLN---SDQKKLYELI 364 >5BO5-A nrPDB Length = 416 Score = 35.2 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 45/271 (16%), Positives = 86/271 (31%), Gaps = 15/271 (5%) Query: 138 DRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKY 197 +D + Y + I+ + + IM A+ I D + Y Sbjct: 152 AKDKTIIFAAIGVPSDIYKMFIDEFINTKA---IMNSAIFISKADSSPIEKIY----TPR 204 Query: 198 FTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRS 257 + + + D++ I KE I G ++ S Sbjct: 205 VALTLAEYLAFEKNRDVLVLMLDMTNYADALREISTLRKE---IPSRRGYPAYLYTDLAS 261 Query: 258 TGSYIAGTNGTSNGLIPMIRVFNNTARYV--DQGGNKRPGAFALYLEPWHADIFDFIDIR 315 T+ S LIPM+ + N +V D G G + L + +I+ ID+ Sbjct: 262 IYERSGLTSKGSITLIPMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLL 321 Query: 316 KNH---GKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYT 372 K+ K + + A + + K +E T+ S Y E + Sbjct: 322 KSLSRLAKNGMSKKHKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYLKFAELVEK 381 Query: 373 RYEKEGRGKTIKAQKLWYSILEAQTETGTPF 403 + K+ + +K + I +++G P+ Sbjct: 382 EFIKQDYYEYRSIEKSFEIIDSILSQSGLPY 412 >6AF0-A nrPDB Length = 939 Score = 32.5 bits (72), Expect = 0.77, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 54/155 (34%), Gaps = 26/155 (16%) Query: 48 YEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNA 107 YEG ++D A ET + + H DY R+A L + K+ V LY+ N Sbjct: 590 YEG----DIDK-AIETYEQLLSRHSDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQ-ENP 643 Query: 108 A----TGKPAPMISDDVYNIVMENKDK-------LNSAIVYDRDFQYSYFGFKTLERSYL 156 + G +S N + ++ YD+ +Y+ G L +L Sbjct: 644 SDLEVRGLYGWFLSKVNSKKRPANIAEDPEQRHYKHTLQSYDKHDRYALVGMGNL---HL 700 Query: 157 LRINGQVAERPQHLIMRVALGIHGRDIEAALETYN 191 + E Q R A A+E ++ Sbjct: 701 MAAREMRRETEQDRQKRSAA------YNRAVEFFD 729 >2ZRW-A nrPDB Length = 368 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 2/79 (2%) Query: 153 RSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPK 212 R+ L RIN +AE + + + +G IE A + ++ P + N G P Sbjct: 71 RNELGRINKIIAEVAEKFGIPMGVGSQRVAIEKAEARESFAIVRKVAPTIPIIANLGMP- 129 Query: 213 PQMSSCFLVAMKEDSIEGI 231 Q+ + + +D+I+ I Sbjct: 130 -QLVKGYGLKEFQDAIQMI 147 >6CES-N nrPDB Length = 380 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 38/108 (35%), Gaps = 2/108 (1%) Query: 671 QGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFY 730 +P ++ +D + + W+++ + I+ +I Q S + + Y Sbjct: 172 YDVPVFTKDKEDFFNSQWDLTTQQILPYIDGF-RHI-QKISAEADVELNLVRIAIQNLLY 229 Query: 731 GWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPS 778 L + + Y + +Q +D K +A + KR S Sbjct: 230 YGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRAS 277 >3U27-C nrPDB Length = 220 Score = 31.4 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 33/107 (30%) Query: 112 PAPMISDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLI 171 P P ++ + + I + D +YF L + E Sbjct: 93 PTPAEVKSGLAAAVDFIENEAAFISANDDDSIAYFAHCISRTGTYLSKTAGIPEGESLAY 152 Query: 172 MRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSC 218 + ++ AL+ ++ + ++ S T F G S+C Sbjct: 153 LIAPPLEAMYALDVALKAADVRLVAFYGPPSETNFGGGLLTGSQSAC 199 >5NUH-A nrPDB Length = 172 Score = 31.0 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 26/78 (33%), Gaps = 5/78 (6%) Query: 290 GNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALW--IPDLFMKRVEENGT 347 +R +YLE I D+ D IR F LW +P +E+ Sbjct: 72 SARRHRILDIYLEKEEGIIPDWQDY---TSGPGIRYPKTFGWLWKLVPVNVSDEAQEDEE 128 Query: 348 WTLFSPTSAPGLSDCYGD 365 L P D +G+ Sbjct: 129 HYLMHPAQTSQWDDPWGE 146 >3IK5-A nrPDB Length = 143 Score = 31.0 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 26/78 (33%), Gaps = 5/78 (6%) Query: 290 GNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALW--IPDLFMKRVEENGT 347 +R +YLE I D+ D IR F LW +P +E+ Sbjct: 43 SARRHRILDIYLEKEEGIIPDWQDY---TSGPGIRYPKTFGWLWKLVPVNVSDEAQEDEE 99 Query: 348 WTLFSPTSAPGLSDCYGD 365 L P D +G+ Sbjct: 100 HYLMHPAQTSQWDDPWGE 117 >6DQU-A nrPDB Length = 530 Score = 30.6 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 55/195 (28%), Gaps = 27/195 (13%) Query: 28 GLDPKHIDAVKVT----QRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAI 83 G +P+ D K + + EG+ T + + A PD+ T Sbjct: 21 GAEPQSFDPHKTEGVPESNVAYQLLEGLVTSDSEGKLQPGAAESWENTPDFKTWT----- 75 Query: 84 SNLHKQTTKQFSKVVE------DLYRYVNAATGKP-----APMISDDVYNIVMENKDKLN 132 +L K V R V+ AT P + + ++ +I+ K Sbjct: 76 FHLRKDAKWSNGDPVTAHDFVFAWRRLVDPATAAPYASYLSYLQVENAQDIIDGKKKPAE 135 Query: 133 SAIVYDRDFQYSY-------FGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEA 185 + D+ + + LL + +V E+ ++ + + Sbjct: 136 LGVEAKDDYTFVVHATNPVPYAVSLTTHQSLLPLPQKVVEKLGDAWVKKENYVGNGAYKL 195 Query: 186 ALETYNLMSLKYFTH 200 A N Sbjct: 196 ANHIINEKIEFERNP 210 >3CWV-A nrPDB Length = 369 Score = 29.4 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 33/100 (33%), Gaps = 6/100 (6%) Query: 200 HASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTG 259 H P +F+ T C L +++ + + + + +R Sbjct: 224 HPEPVVFDF-TWDGLRVQCALQWCEDE--DSTLLSFANAVRTVRHGAHVKGVTQALR--- 277 Query: 260 SYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFAL 299 +A +G + G P RV V G +R AFA Sbjct: 278 GALAKLSGETRGAFPWARVAQGLTAIVAVSGPRRQMAFAG 317 >5FL8-r nrPDB Length = 767 Score = 29.4 bits (64), Expect = 6.5, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 40/123 (32%), Gaps = 4/123 (3%) Query: 14 QFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAETCAYMTTVHP- 72 +I + ++ C+ L P + V V + V +GV E+ T + + P Sbjct: 399 DVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVAN-EVAAAGINTIREICSRAPL 457 Query: 73 --DYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDK 130 D L + + +K + LYR V K + + K Sbjct: 458 AIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGG 517 Query: 131 LNS 133 +S Sbjct: 518 KDS 520 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.119 0.292 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,561,117 Number of Sequences: 36641 Number of extensions: 1072851 Number of successful extensions: 3107 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2936 Number of HSP's gapped (non-prelim): 77 length of query: 888 length of database: 10,336,785 effective HSP length: 106 effective length of query: 782 effective length of database: 6,452,839 effective search space: 5046120098 effective search space used: 5046120098 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.0 bits)