BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P21266 (225 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3GTU-B nrPDB 468 e-132 4GTU-A nrPDB 338 9e-94 1XWK-A nrPDB 335 1e-92 2DC5-A nrPDB 327 2e-90 5FWG-A nrPDB 325 1e-89 1HNA-A nrPDB 323 5e-89 1B4P-A nrPDB 318 1e-87 1GSU-A nrPDB 298 1e-81 5AN1-A nrPDB 234 2e-62 2FHE-A nrPDB 204 2e-53 4Q5Q-A nrPDB 197 3e-51 2WRT-A nrPDB 187 4e-48 1FHE-A nrPDB 178 2e-45 1B8X-A nrPDB 158 2e-39 1BG5-A nrPDB 157 3e-39 1DUG-A nrPDB 157 4e-39 4WR5-A nrPDB 150 3e-37 5D73-A nrPDB 120 7e-28 18GS-A nrPDB 119 1e-27 2GLR-A nrPDB 117 6e-27 2GSR-A nrPDB 115 1e-26 1TU7-A nrPDB 113 5e-26 5Y9Z-A nrPDB 75 2e-14 4Q5R-A nrPDB 75 2e-14 2AAW-A nrPDB 75 2e-14 3KXO-A nrPDB 74 4e-14 1M0U-A nrPDB 74 7e-14 1EV4-A nrPDB 72 2e-13 1F3B-A nrPDB 71 3e-13 5LCZ-A nrPDB 69 2e-12 1ZL9-A nrPDB 65 2e-11 2VCT-A nrPDB 65 2e-11 1YQ1-A nrPDB 65 2e-11 4Q5F-A nrPDB 62 1e-10 2VCV-A nrPDB 60 8e-10 1PL2-A nrPDB 60 9e-10 1GSQ-A nrPDB 60 1e-09 3I6A-A nrPDB 59 1e-09 1B48-A nrPDB 57 9e-09 2CA8-A nrPDB 52 3e-07 1U3I-A nrPDB 50 6e-07 2WDU-A nrPDB 45 2e-05 1VF1-A nrPDB 45 3e-05 6F05-A nrPDB 44 6e-05 1GUL-A nrPDB 44 8e-05 5F07-A nrPDB 41 3e-04 2HNL-A nrPDB 41 4e-04 1AXD-A nrPDB 34 0.049 4IKH-A nrPDB 32 0.23 3G0T-A nrPDB 32 0.25 3LFL-A nrPDB 29 1.5 3W6N-A nrPDB 29 1.9 4BEJ-A nrPDB 29 2.0 4IKD-A nrPDB 29 2.1 1AW9-A nrPDB 28 2.3 5A5K-A nrPDB 28 2.8 5WP9-A nrPDB 28 3.5 4PNG-A nrPDB 28 3.6 2C3Q-A nrPDB 27 5.8 3UDO-A nrPDB 27 6.0 3VIB-A nrPDB 27 6.2 >3GTU-B nrPDB Length = 224 Score = 468 bits (1204), Expect = e-132, Method: Compositional matrix adjust. Identities = 224/224 (100%), Positives = 224/224 (100%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF Sbjct: 1 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 60 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS Sbjct: 61 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 120 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE Sbjct: 121 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 180 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC 225 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC Sbjct: 181 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC 224 >4GTU-A nrPDB Length = 217 Score = 338 bits (868), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 157/217 (72%), Positives = 183/217 (84%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 SM LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 1 SMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 YL+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL R+CYS D E Sbjct: 61 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFE 120 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 KLKP+YLEELP ++ FS FLGK WF G+K+TFVDFL YD+LD +RIF+P CLD FPNL Sbjct: 121 KLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNL 180 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 K F+ RFE LEKI+AY++S +F P+ ++A WGNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1XWK-A nrPDB Length = 218 Score = 335 bits (858), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 158/216 (73%), Positives = 185/216 (85%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M+LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL +CY+ + EK Sbjct: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 LKP+YLEELP +LK +S FLGK WFAG K+TFVDFL YD+LD +RIF+PKCLD FPNLK Sbjct: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFE LEKI+AY++S +F P+ +KMA WGNK Sbjct: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >2DC5-A nrPDB Length = 231 Score = 327 bits (838), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 148/220 (67%), Positives = 184/220 (83%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 S M LGYWDIRGLAHAIRL LE+TD+SYEEKRYT G+APDYD+SQWL+ KFKL LDF Sbjct: 5 SSGMPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDF 64 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 PNLPYL+DG +KITQSNAILRY+ RKHN+CGETEEE+IRVDI+ENQ+MD R L RLCY+ Sbjct: 65 PNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYN 124 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 +D EKLKP YLE+LPG ++ +S FLGK WFAG+K+TFVDF+ YD+L++N++F+ KCLD Sbjct: 125 ADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDA 184 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 FPNLK F+ RFE L+KI+ Y+++ +F P+ KMA WG+ Sbjct: 185 FPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >5FWG-A nrPDB Length = 217 Score = 325 bits (832), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 147/216 (68%), Positives = 182/216 (84%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 2 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 61 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L+DG KITQSNAI+RY+ARKH++CGETEEE+IR DI+ENQVMD R QLI LCY+ D EK Sbjct: 62 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 121 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 KP++L+ +P ++K +S FLGK WFAG+K+T+VDFL YDILDQ IF+PKCLD FPNLK Sbjct: 122 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 181 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFE L+KI+AY++S ++ PI +K+AQW NK Sbjct: 182 DFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >1HNA-A nrPDB Length = 217 Score = 323 bits (827), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 148/216 (68%), Positives = 182/216 (84%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M LGYW+IRGLAH+IRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 2 MTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 61 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L+DG +KITQSNAILRYIARKHN+CGE+E+E+IR DI+ENQ MD R QL +LCY D EK Sbjct: 62 LIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEK 121 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 LKP+YL+ LP LK +S FLGK WF G+K+TFVDF+ YD+L++N++F+P CLD FPNLK Sbjct: 122 LKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLK 181 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFE LEKI+AY++S +F P+ KMA +GNK Sbjct: 182 DFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >1B4P-A nrPDB Length = 217 Score = 318 bits (815), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 146/216 (67%), Positives = 178/216 (82%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 2 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 61 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L+DG KITQSNAI+RY+ARKH++CGETEEE+IRVD++ENQ MD R QL +CYS D E+ Sbjct: 62 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFER 121 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 KP+YLE LP ++K +S FLGK WFAG K+T+VDFL YD+LDQ+RIF+PKCLD FPNLK Sbjct: 122 KKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNLK 181 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFE L+KI+ Y++S +F PI KMA W K Sbjct: 182 DFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >1GSU-A nrPDB Length = 219 Score = 298 bits (762), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 143/216 (66%), Positives = 167/216 (77%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 + LGYWDIRGLAHAIRLLLE+T+T Y+E+RY G APD+D S W + K KL LDFPNLPY Sbjct: 2 VTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPY 61 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L+DG K+TQSNAILRYIARKHNMCGETE EK RVD++EN +MD R RLCYS D EK Sbjct: 62 LIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEK 121 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 LKP YLE+LPG+L+Q S FLG SWF G+KLTFVDFL YD+LDQ R+F P C + NL Sbjct: 122 LKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLS 181 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFEALEKI+AY++S +F K PI A W NK Sbjct: 182 QFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >5AN1-A nrPDB Length = 219 Score = 234 bits (598), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 115/212 (54%), Positives = 143/212 (67%), Gaps = 2/212 (0%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 VLGYW R L IRL+L +T T +EEK Y G+APDYD+S+WL VKFKL L FPNLPY Sbjct: 4 VLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYY 63 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 +DG KITQS AI+RY+ARKH +CG T EE +R D+IE Q+ D + Y +H + Sbjct: 64 IDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EHYEQ 121 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKA 187 K Y LP +L+Q+S FLG WFAG+KLT++DFL Y+I DQ+ D CLD F NL+A Sbjct: 122 KDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKNLQA 181 Query: 188 FMCRFEALEKIAAYLQSDQFCKMPINNKMAQW 219 F RFE LE I Y+ S +F K PI NK AQ+ Sbjct: 182 FQKRFEDLEAIKKYMASPKFLKKPICNKYAQF 213 >2FHE-A nrPDB Length = 216 Score = 204 bits (519), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 103/213 (48%), Positives = 133/213 (62%), Gaps = 5/213 (2%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 LGYW IRGL +RLLLE+ YEE+ Y D +W KF+L LD PNLPY + Sbjct: 4 LGYWKIRGLQQPVRLLLEYLGEKYEEQIYERD-----DGEKWFSKKFELGLDLPNLPYYI 58 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128 D K K+TQS AILRYIA KH M G T EE+ RV +IE +D R + R+ Y E+LK Sbjct: 59 DDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFEQLK 118 Query: 129 PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 YL++LP +K +S FLGK + G ++ VDF+ Y+ LD R +P CLD FPNL+ F Sbjct: 119 EGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNLQQF 178 Query: 189 MCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 M R EAL I AY++S++F K P+N AQ+G Sbjct: 179 MSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >4Q5Q-A nrPDB Length = 219 Score = 197 bits (501), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 91/202 (45%), Positives = 135/202 (66%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S +LGYWDIRG A IRLLL ++ + +KRY G APD+DRS+WL+ KF L LDFPNL Sbjct: 2 SQPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNL 61 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 PY +DG K+TQ+ AILRY+ RK+ + G + E+IR+ + E Q D +IR+CY ++ Sbjct: 62 PYYIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANC 121 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPN 184 +KLKP YL+ LP LK S F+G+ ++ AG +++VDF Y+ L ++ P+ +F N Sbjct: 122 DKLKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFEN 181 Query: 185 LKAFMCRFEALEKIAAYLQSDQ 206 LK ++ R E+L +++ Y++ Q Sbjct: 182 LKRYVERMESLPRVSDYIKKQQ 203 >2WRT-A nrPDB Length = 218 Score = 187 bits (474), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 101/213 (47%), Positives = 134/213 (62%), Gaps = 5/213 (2%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 LGYW IRGL +RLLLE+ YEE Y DR +WL KF + LD PNLPY + Sbjct: 5 LGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRD-----DREKWLGDKFNMGLDLPNLPYYI 59 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128 D K K+TQS AI+RYIA KH M G T EE+ R+ +IE MD R +R+CY+ E++K Sbjct: 60 DDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKFEEVK 119 Query: 129 PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 YL+ELP LK +S FLG + G ++ VDF+ Y+ LD R P+CL++FP LK F Sbjct: 120 GDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPKLKEF 179 Query: 189 MCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 R E L KI AY++S++F K P+N+ +A +G Sbjct: 180 KSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >1FHE-A nrPDB Length = 217 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 101/212 (47%), Positives = 131/212 (61%), Gaps = 5/212 (2%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 LGYW +RGLA +RL LE+ YEE Y DR +W+ KF + LD PNLPY + Sbjct: 4 LGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRD-----DREKWMSEKFNMGLDLPNLPYYI 58 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128 D K K+TQS AI+RYIA KH M G T EE+ R+ +IE MD R R+CY+ E++K Sbjct: 59 DDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFEEVK 118 Query: 129 PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 +Y++ELP LK +S FLG + G ++ VDF+ Y+ LD R P CLDEFP LK F Sbjct: 119 EEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKLKEF 178 Query: 189 MCRFEALEKIAAYLQSDQFCKMPINNKMAQWG 220 R EAL KI AY++S +F K P+N A +G Sbjct: 179 KSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >1B8X-A nrPDB Length = 280 Score = 158 bits (399), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 92/216 (42%), Positives = 125/216 (57%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >1BG5-A nrPDB Length = 254 Score = 157 bits (398), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 92/216 (42%), Positives = 125/216 (57%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNLP Sbjct: 2 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 56 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 57 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 116 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP L Sbjct: 117 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 176 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 177 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 212 >1DUG-A nrPDB Length = 234 Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 92/216 (42%), Positives = 125/216 (57%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >4WR5-A nrPDB Length = 244 Score = 150 bits (380), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 90/216 (41%), Positives = 121/216 (56%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE + YEE E +W + KF+L L+FPNLP Sbjct: 26 SPILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-----DKWRNKKFELGLEFPNLP 80 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+R IA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 81 YXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 140 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L + G+ +T DF+ YD LD DP CLD FP L Sbjct: 141 TLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKL 200 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 201 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 236 >5D73-A nrPDB Length = 208 Score = 120 bits (300), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 76/219 (34%), Positives = 115/219 (52%), Gaps = 18/219 (8%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y+ IRGLA IRL+L + + R + P K F LP Sbjct: 2 SYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWP----------SMKSHFHFGQLP 51 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 L DG ++I QS AILR++ARKHN+ G E E +D+ V D T+ ++ Y + ++ Sbjct: 52 CLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQA-YD 110 Query: 126 KLKPQYLEE-LPGQLKQFSMFL-----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 K Y+++ LP +L +F L GK ++ GEK+++VDF+ ++ LD ++I DP CL Sbjct: 111 TEKDSYIKDILPVELAKFEKLLATRDDGK-NFILGEKISYVDFVLFEELDIHQILDPHCL 169 Query: 180 DEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 D+FP LKA+ R E + Y + K+P+N Q Sbjct: 170 DKFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPVNGNGKQ 208 >18GS-A nrPDB Length = 210 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 13/212 (6%) Query: 11 YWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDG 70 Y+ +RG A+R+LL S++E+ T W + K + LP DG Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLPKFQDG 59 Query: 71 KNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQ 130 + QSN ILR++ R + G+ ++E VD++ + V D R + I L Y+ ++E K Sbjct: 60 DLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYEAGKDD 118 Query: 131 YLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 Y++ LPGQLK F L G ++ G++++F D+ D+L + + P CLD FP L Sbjct: 119 YVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLS 178 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 A++ R A K+ A+L S ++ +PIN Q Sbjct: 179 AYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 210 >2GLR-A nrPDB Length = 209 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%) Query: 11 YWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDG 70 Y+ +RG A+R+LL S++E+ T W+ K + LP DG Sbjct: 7 YFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLPKFEDG 58 Query: 71 KNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQ 130 + QSNAILR++ R + G+ + E ++D++ + V D R + + L Y+ ++E K Sbjct: 59 DLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYENGKND 117 Query: 131 YLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 Y++ LPG LK F L G ++ G++++F D+ D+L +++ P CLD FP L Sbjct: 118 YVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLS 177 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 A++ R A KI A+L S + PIN Q Sbjct: 178 AYVARLSARPKIKAFLSSPEHVNRPINGNGKQ 209 >2GSR-A nrPDB Length = 207 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 70/215 (32%), Positives = 110/215 (51%), Gaps = 15/215 (6%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 + Y+ +RG A+R+LL D S++E+ T P K F LP Sbjct: 4 TITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWP----------PLKPSCLFRQLPKF 53 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 DG + QSNAILR++ R + G+ ++E VD++ + V D R + L Y+ ++E Sbjct: 54 QDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYEAG 112 Query: 128 KPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFP 183 K +Y++ELP LK F L G ++ G +++F D+ D+L +++ +P CLD FP Sbjct: 113 KEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFP 172 Query: 184 NLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 L A++ R A KI A+L S + PIN Q Sbjct: 173 LLSAYVARLSARPKIKAFLASPEHVNRPINGNGKQ 207 >1TU7-A nrPDB Length = 208 Score = 113 bits (283), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 71/217 (32%), Positives = 107/217 (49%), Gaps = 14/217 (6%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y+ IRGLA IRL L D + + R + + +K + F LP Sbjct: 2 SYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIA--------KDDFSSIKSQFQ--FGQLP 51 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 L DG +I QS AILR++ARK+N+ GE E E +D+ V D + R+ Y + Sbjct: 52 CLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYET 111 Query: 126 KLKPQYLEELPGQLKQFSMFLGK----FSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 + P LPG+L +F L + G+K+++ D+ ++ LD ++I DP CLD+ Sbjct: 112 EKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLDK 171 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 FP LK F R + K+ Y + K+P+N Q Sbjct: 172 FPLLKVFHQRMKDRPKLKEYCEKRDAAKVPVNGNGKQ 208 >5Y9Z-A nrPDB Length = 199 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 55/200 (27%), Positives = 95/200 (47%), Gaps = 20/200 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 L Y+++RG A IR + + D YE+ R + P K K L F +P L Sbjct: 6 LLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGKIPVLE 55 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128 + QS AI RY+ + ++ G+TE E+ +VD + + + DF + ++ +++ LK Sbjct: 56 VEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMS---LFPWAEENQDLK 112 Query: 129 PQYLEEL-----PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQN-RIFDPKCLDEF 182 + +L P LK +LG WF G +T+ DF +DI + P L + Sbjct: 113 ERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFY-WDICSTTLLVLKPDLLGIY 171 Query: 183 PNLKAFMCRFEALEKIAAYL 202 P L + + +A+ I+A++ Sbjct: 172 PRLVSLRNKVQAIPAISAWI 191 >4Q5R-A nrPDB Length = 204 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/204 (28%), Positives = 94/204 (46%), Gaps = 18/204 (8%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y ++ L IR LL + + +E+ R+ G+ P+ K + F P Sbjct: 4 SYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPN----------LKPSMPFGKTP 53 Query: 66 YL-LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD- 123 L +DGK + QS AI RY+ ++ + G+ + E + +D+I + + DFR + Y +D Sbjct: 54 VLEIDGK-QTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADE 112 Query: 124 ---HEKLKPQYLEELPGQLKQFSMFL-GKFSWFAGEKLTFVDFLTYDILDQ-NRIFDPKC 178 +K P E +P K+F + + A KLT+ DF ILD N + Sbjct: 113 NSKQKKWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDL 172 Query: 179 LDEFPNLKAFMCRFEALEKIAAYL 202 + PNLKA + L I A++ Sbjct: 173 VANQPNLKALREKVLGLPAIKAWV 196 >2AAW-A nrPDB Length = 222 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 61/212 (28%), Positives = 94/212 (44%), Gaps = 15/212 (7%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTC-GEAPDYDRSQWLDVKFKLDLD 60 S ++VL Y+D RG A IRL+ + Y +KR+ G+A ++ + K + D Sbjct: 11 SMGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDA----FVEFKNFKKEKDTP 66 Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY 120 F +P L G + QS AI+RY+++K+N+CGE+E + D+I V D + Sbjct: 67 FEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNL 126 Query: 121 SSDHEKLKPQYLEELPGQLKQFSMFLGKFS--------WFAGEKLTFVDFLTYDILDQNR 172 +E E+LP F L K +F G LT+ D +++ D Sbjct: 127 FKQNETTFLN--EDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIE 184 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQS 204 P L FP LKA L I Y+ + Sbjct: 185 TKYPSSLKNFPLLKAHNEFISNLPNIKNYITN 216 >3KXO-A nrPDB Length = 202 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 22/202 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 L Y+++RG A IR + + D YE+ R + P+ K L F +P L Sbjct: 9 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 58 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK-- 126 + QS AI RY+ + ++ G TE E+ VD I + + DF + C+ +K Sbjct: 59 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS-----CFPWAEKKQD 113 Query: 127 LKPQYLEEL-----PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 +K Q EL P ++ +LG W G +T+ DF +F P LD Sbjct: 114 VKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN 173 Query: 182 FPNLKAFMCRFEALEKIAAYLQ 203 P L + +A+ +A +++ Sbjct: 174 HPRLVTLRKKVQAIPAVANWIK 195 >1M0U-A nrPDB Length = 249 Score = 73.6 bits (179), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 57/219 (26%), Positives = 106/219 (48%), Gaps = 40/219 (18%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 + S L Y++++ LA +R L + + YE+ R T R +W +K + + Sbjct: 46 IKHSYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVT--------RDEWPALKPTMPMG-- 95 Query: 63 NLPYL-LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 +P L +DGK ++ QS ++ R++A+ +CG T E +++DI+ + + DFR ++ + Y Sbjct: 96 QMPVLEVDGK-RVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYE 154 Query: 122 SDHE-----------KLKPQYLEELPGQLK--QFSMFLGKFSW----FAGEKLTFVDFLT 164 + E ++ P YLE+L +K + LGK +W FAG D++ Sbjct: 155 PEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAG----ITDYMN 210 Query: 165 YDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQ 203 Y + L+ +P L+ + ALE I A+++ Sbjct: 211 Y-------MVKRDLLEPYPALRGVVDAVNALEPIKAWIE 242 >1EV4-A nrPDB Length = 221 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 63/226 (27%), Positives = 101/226 (44%), Gaps = 24/226 (10%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 VL Y++ RG IR LL ++EK E D ++ +K +L F +P + Sbjct: 5 VLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPE--DLEK-----LKKDGNLMFDQVPMV 57 Query: 68 -LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 +DG K+ Q+ AIL YIA K+++ G+ +E+ +D+ ++D +++L +K Sbjct: 58 EIDGM-KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQK 116 Query: 127 ----------LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 K +YL LK + G KLT VD ++L FD Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNKLTRVDIHLLELLLYVEEFDA 171 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP LKAF R +L + +LQ K+P++ K + K Sbjct: 172 SLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARK 217 >1F3B-A nrPDB Length = 222 Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 65/226 (28%), Positives = 99/226 (43%), Gaps = 24/226 (10%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 VL Y++ RG IR LL +EEK E D ++ +K +L F +P + Sbjct: 5 VLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPE--DLEK-----LKKDGNLMFDQVPMV 57 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIR---LCYSSDH 124 K+ Q+ AIL YIA K+++ G+ +E+ +D+ ++D T++I LC Sbjct: 58 EIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDL-TEMIGQLVLCPPDQR 116 Query: 125 E--------KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 E + K +YL LK + G +LT VD ++L FD Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLEVLLYVEEFDA 171 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP LKAF R +L + +LQ K P++ K Q K Sbjct: 172 SLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARK 217 >5LCZ-A nrPDB Length = 222 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 63/225 (28%), Positives = 96/225 (42%), Gaps = 24/225 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y++ RG + R LL +EEK E D R+ L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRL--CYSSDHE 125 +DG K+ Q+ AIL YIA K+N+ G+ +E+ +D+ ++D +I+L C E Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQRE 118 Query: 126 --------KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 + K +YL LK + G +LT VD ++L FD Sbjct: 119 AKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLELLLYVEEFDAS 173 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP LKAF R +L + +LQ K ++ K + K Sbjct: 174 LLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARK 218 >1ZL9-A nrPDB Length = 207 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 58/212 (27%), Positives = 99/212 (46%), Gaps = 26/212 (12%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y++ RG R + + YE+ R T + QW +K F LP Sbjct: 3 SYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQLP 54 Query: 66 YL-LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS--- 121 +L +DGK K+ QS+AI R++AR+ + G+T E+ +V+ + +Q D+ ++ Y+ Sbjct: 55 FLEVDGK-KLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMG 113 Query: 122 ---SDHEKLKPQYLEELPGQLKQFSMFLGKF------SWFAGEKLTFVDFLTYDILDQNR 172 D E LK LP ++F FL F + G+ LT++D L + Sbjct: 114 FGPGDVETLKKDIF--LPA-FEKFYGFLVNFLKASGSGFLVGDSLTWID-LAIAQHSADL 169 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQS 204 I +FP LKA + +A+ +I ++++ Sbjct: 170 IAKGGDFSKFPELKAHAEKIQAIPQIKKWIET 201 >2VCT-A nrPDB Length = 222 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/225 (27%), Positives = 92/225 (40%), Gaps = 24/225 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y +IRG +IR LL +EEK E D R+ L F +P + Sbjct: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD---- 123 +DG K+ Q+ AIL YIA K+N+ G+ +EK +D+ + D ++ L ++ Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQD 118 Query: 124 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 EK K +Y LK + G KL+ D ++L D Sbjct: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 + FP LKA R L + +LQ K P++ K + K Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 >1YQ1-A nrPDB Length = 208 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/223 (27%), Positives = 91/223 (40%), Gaps = 34/223 (15%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y+ RGL IRLL +EE R PD WLD+K + LP Sbjct: 3 SYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMN----PD---QTWLDIKDSTPMK--QLP 53 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY----- 120 L ++ QS AILRY+ARK G+T EE+ VD + + DF + + Sbjct: 54 VLNIDGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSG 113 Query: 121 --SSDHEKLKPQYLEELPGQLKQFSMFLGKF-----SWFAGEKLTFVDFLTYD---ILDQ 170 + + EK + ++ LP + F++ G + G +TF D + D L Sbjct: 114 KSAEEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKN 171 Query: 171 NRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPIN 213 +FD EF L A + + I Y+ K P+ Sbjct: 172 YGLFDE---SEFTKLAALREKVNSYPGIKEYI-----AKRPVT 206 >4Q5F-A nrPDB Length = 218 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 58/204 (28%), Positives = 88/204 (43%), Gaps = 21/204 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 L Y+DIRGL RL+ +E+ R R W +K K F LP L Sbjct: 18 LTYFDIRGLGEGARLIFHQAGVKFEDNRLK--------REDWPALKPKTP--FGQLPLLE 67 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY---SSDHE 125 + QS AI RY+ R+ + G+T E+ +VD I +Q DF +L R C+ + E Sbjct: 68 VDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAEL-RPCFRVLAGFEE 126 Query: 126 KLKPQYLEE--LPGQLKQFSM---FLGKFS--WFAGEKLTFVDFLTYDILDQNRIFDPKC 178 K + L+E +P + K + FL K + G+ +T+ D + D L P Sbjct: 127 GDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDF 186 Query: 179 LDEFPNLKAFMCRFEALEKIAAYL 202 L LK ++ L I ++ Sbjct: 187 LSGHLQLKKYIEHVRELPNIKKWI 210 >2VCV-A nrPDB Length = 222 Score = 60.1 bits (144), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 60/225 (26%), Positives = 92/225 (40%), Gaps = 24/225 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y++ RG IR LL +EEK G A D + ++ L F +P + Sbjct: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGK-----LRNDGSLMFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ--LIRLCYSSD-- 123 +DG K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D L+ LC + Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 Query: 124 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 EK K +Y L+ + G KL+ D ++L D Sbjct: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS 173 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 + FP LKA R L + +LQ K P + K + K Sbjct: 174 LISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 >1PL2-A nrPDB Length = 222 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 59/225 (26%), Positives = 91/225 (40%), Gaps = 24/225 (10%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y++ RG + R LL +EEK E D R+ L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRL--CYSSD-- 123 +DG K+ Q AIL YIA K+N+ G+ +E+ +D+ + D ++ L C + Sbjct: 60 IDGM-KLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKD 118 Query: 124 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 EK+K +Y LK + G KL+ D ++L D Sbjct: 119 AKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 + FP LKA R L + +LQ K P++ K + K Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARK 218 >1GSQ-A nrPDB Length = 202 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 20/204 (9%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 L Y+ + G A R +L + ++ + P+ + + + LD+D Sbjct: 4 TLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDID------- 56 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 K++QS I R++AR+ + G+T EK RVD I + D ++++ ++ + K Sbjct: 57 ---GTKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKE 113 Query: 128 KPQYLEELPGQLKQFSMFL--------GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 Q + K+ + FL G +F G +T D Y L+ P+ L Sbjct: 114 AVQ--QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELL 171 Query: 180 DEFPNLKAFMCRFEALEKIAAYLQ 203 + P + A R KIAAYL+ Sbjct: 172 KDCPKIVALRKRVAECPKIAAYLK 195 >3I6A-A nrPDB Length = 222 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 24/214 (11%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y++ RG + R LL +EEK E D R+ L F +P + Sbjct: 7 LHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH--- 124 +DG K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D +I L + Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKD 118 Query: 125 -------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 EK+K +Y LK + G KL+ D ++L D Sbjct: 119 AKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 + FP LKA R L + +LQ K P Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >1B48-A nrPDB Length = 221 Score = 56.6 bits (135), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 12/208 (5%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 L Y++ RG +IR LL +EE+ R Q+ ++ L F +P + Sbjct: 6 LYYFNGRGRMESIRWLLAAAGVEFEEEFLET-------REQYEKMQKDGHLLFGQVPLVE 58 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128 +TQ+ AIL Y+A K+N+ G+ +E++R+D+ + D + + + EK + Sbjct: 59 IDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEE 118 Query: 129 PQYLEELPGQLKQFSMFLGKF-----SWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFP 183 L + + F +F ++ G +L++ D + + L +FP Sbjct: 119 SYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFP 178 Query: 184 NLKAFMCRFEALEKIAAYLQSDQFCKMP 211 L+AF R + I +LQ K P Sbjct: 179 LLQAFKTRISNIPTIKKFLQPGSQRKPP 206 >2CA8-A nrPDB Length = 211 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 84/191 (43%), Gaps = 31/191 (16%) Query: 11 YWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDG 70 Y++ RG A +IR+ L +YE++R + + P K K + LP + Sbjct: 10 YFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIPGGRLPAVKIT 59 Query: 71 KNK-----ITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 N + +S AI RY+A+KH+M G TEEE V+ + Q D + + + E Sbjct: 60 DNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEE 119 Query: 126 KLK----------PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFD 175 K K P L+ + LK + GK + G+K+T D + ++D D Sbjct: 120 KQKIIKEILNGKVPVLLDIICESLKAST---GKLA--VGDKVTLADLVLIAVIDHVTDLD 174 Query: 176 PKCL-DEFPNL 185 + L ++P + Sbjct: 175 KEFLTGKYPEI 185 >1U3I-A nrPDB Length = 211 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 52/183 (28%), Positives = 82/183 (44%), Gaps = 27/183 (14%) Query: 1 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD 60 M+ E V+ Y+D RG A +IR+ L YE++R + + P K K + Sbjct: 1 MAGEHIKVI-YFDGRGRAESIRMTLVAAGVDYEDERISFQDWP----------KIKPTIP 49 Query: 61 FPNLPYL--LDGKNKIT---QSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQL 115 LP + D + +S AI RY+A+KH+M GET+EE V+ + Q D + Sbjct: 50 GGRLPAVKVTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEY 109 Query: 116 IRLCYSSDHEKLKPQYLEELPGQLKQ-FSMF-------LGKFSWFAGEKLTFVDFLTYDI 167 + EK K E L G++ F+M GK + G+K+T D + + Sbjct: 110 HKTLMKPQEEKEKITK-EILNGKVPVLFNMICESLKGSTGKLA--VGDKVTLADLVLIAV 166 Query: 168 LDQ 170 +D Sbjct: 167 IDH 169 >2WDU-A nrPDB Length = 211 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 78/189 (41%), Gaps = 17/189 (8%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 L Y+ RG A IRLLL +E+ ++T + P + LD+ P Sbjct: 8 LWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPTIKPTLPGGRVPLLDVTGP------ 61 Query: 69 DGK-NKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ---LIRLCYSSDH 124 DGK + +S AI R +AR+ M GET+EE ++ I + D + + R Sbjct: 62 DGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEKE 121 Query: 125 EKLKPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 K+K P LK S L GK AG ++T D + L P L+ Sbjct: 122 AKIKEFKENNGPTLLKLVSESLESSGGKH--VAGNRITLGDLFLFTTLTHVMETVPGFLE 179 Query: 181 E-FPNLKAF 188 + FP L F Sbjct: 180 QKFPKLHEF 188 >1VF1-A nrPDB Length = 229 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 30/209 (14%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 VL Y++ RG +IR LL +EE R Q+ + L F +P + Sbjct: 6 VLYYFNGRGKMESIRWLLAAAGVEFEEVFLET-------REQYEKLLQSGILMFQQVPMV 58 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 K+ Q+ AIL YIA K+N+ G+ +E+ +D+ D L+ + S +K+ Sbjct: 59 EIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKV 118 Query: 128 K--------------PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 K P Y + L + F G +L++ D + + Sbjct: 119 KQCAFVVEKATSRYFPAYEKVLKDHGQDF---------LVGNRLSWADIHLLEAILMVEE 169 Query: 174 FDPKCLDEFPNLKAFMCRFEALEKIAAYL 202 L FP L+AF R ++ I +L Sbjct: 170 KKSDALSGFPLLQAFKKRISSIPTIKKFL 198 >6F05-A nrPDB Length = 215 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 17/118 (14%) Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKH-----NMCGETEEEKIRVD-IIENQVMDFRTQ 114 F +P ++DG KI +S A++RY+A K+ ++ G+T E++ +V+ ++ + + Sbjct: 50 FGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPP 109 Query: 115 LIRLC----------YSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDF 162 L+ L + SD EKL + E+L G L + L K + AG+ ++ D Sbjct: 110 LLNLTLHIMFASVMGFPSD-EKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADL 166 >1GUL-A nrPDB Length = 222 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 51/215 (23%), Positives = 86/215 (40%), Gaps = 26/215 (12%) Query: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 67 L Y + RG ++R +L ++E+ E Q ++ L F +P + Sbjct: 7 LHYPNGRGRMESVRWVLAAAGVEFDEEFLETKE-------QLYKLQDGNHLLFQQVPMVE 59 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 +DG K+ Q+ +IL YIA KHN+ G+ +E+ +D+ +D LI H L Sbjct: 60 IDGM-KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIM------HPFL 112 Query: 128 KP--QYLEELPGQLKQFSMFLGKF---------SWFAGEKLTFVDFLTYDILDQNRIFDP 176 KP Q E + K + F S+ G +L+ D + + P Sbjct: 113 KPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIP 172 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 L FP L+ + + + I +L+ K P Sbjct: 173 NILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPP 207 >5F07-A nrPDB Length = 213 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 17/125 (13%) Query: 54 KFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKH-----NMCGETEEEKIRVD-IIENQ 107 +F L F +P + DG K+ +S AI+RY A K+ N+ G T EEK VD +E + Sbjct: 43 EFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIE 102 Query: 108 VMDFR----------TQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKL 157 +F L R+ D E ++ Y E+L L + L K + AG+ Sbjct: 103 AHNFNDLVFNIVFQVVILPRIGQQGDSELVR-TYEEKLEKVLDVYEKRLSKSKYLAGDSF 161 Query: 158 TFVDF 162 T D Sbjct: 162 TLADL 166 >2HNL-A nrPDB Length = 225 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 24/205 (11%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 L Y++ RG A IRLL + SYE+ R T R +W +K + F ++P L Sbjct: 29 TLTYFNGRGRAEVIRLLFALANVSYEDNRIT--------RDEWKYLKPR--TPFGHVPML 78 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 N + +S+AI + + + G + E+ ++ + + + +LI + + K Sbjct: 79 NVSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTK- 137 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWF---------AGEKLTFVDFLTYDILDQNRIFDPKC 178 K + L FLG++ F G K++ D +++L + D Sbjct: 138 KAELFRNLSES--DVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMT--LDDEVK 193 Query: 179 LDEFPNLKAFMCRFEALEKIAAYLQ 203 L+E+P L +F+ + + I +++ Sbjct: 194 LEEYPQLASFVNKIGQMPGIKEWIK 218 >1AXD-A nrPDB Length = 209 Score = 34.3 bits (77), Expect = 0.049, Method: Compositional matrix adjust. Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 19/160 (11%) Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKHN---MCGETEEEKIRVDI-IENQVMDFRTQLI 116 F +P L DG + +S AI +Y ARK+ + EE VD+ IE + + L Sbjct: 51 FGQVPALQDGDLYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALN 110 Query: 117 RLCY---------SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDI 167 + + + +K+ + LE+L L+ + L K + AG+ L+ D L + Sbjct: 111 PILFQVLISPMLGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLAD-LNHVS 169 Query: 168 LDQNRIFDP--KCLDEFPNLKAF---MCRFEALEKIAAYL 202 + P LD +P++KA+ + +++K+AA + Sbjct: 170 VTLCLFATPYASVLDAYPHVKAWWSGLMERPSVQKVAALM 209 >4IKH-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 77/198 (38%), Gaps = 35/198 (17%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPN--LPYLLDGKN------ 72 + ++LE YE R + E D ++L V PN +P +LD Sbjct: 36 VSIMLEEIGLPYEAHRVSF-ETQDQMTPEFLSVS-------PNNKIPAILDPHGPGDQPL 87 Query: 73 KITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS---------- 122 + +S AIL Y+A K +E R + I Q + F+ I + Sbjct: 88 ALFESGAILIYLADKSGQL-LAQESAARYETI--QWLMFQMGGIGPMFGQVGFFNKFAGR 144 Query: 123 DHEKLKP--QYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY----DILDQNRIFDP 176 ++E +P +Y+ E L LG W GE+ T D T+ +++ + Sbjct: 145 EYEDKRPLERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIGFYEAGEL 204 Query: 177 KCLDEFPNLKAFMCRFEA 194 +D FP +K + +F A Sbjct: 205 VGIDNFPEVKRVLAKFVA 222 >3G0T-A nrPDB Length = 437 Score = 31.6 bits (70), Expect = 0.25, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 16/72 (22%) Query: 159 FVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCR-----FEAL-----------EKIAAYL 202 FV FL + +NR + +D NL CR FE+ EK+ +YL Sbjct: 119 FVSFLVANRTHKNREYGTLFIDPGFNLNKLQCRILGQKFESFDLFEYRGEKLREKLESYL 178 Query: 203 QSDQFCKMPINN 214 Q+ QFC + +N Sbjct: 179 QTGQFCSIIYSN 190 >3LFL-A nrPDB Length = 240 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/102 (21%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 106 NQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY 165 ++V IR D+ LK ++ +E K + K ++F G ++ +D+L + Sbjct: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEF---TKLEVLTNKKTTFFGGNSISMIDYLIW 177 Query: 166 DILDQNRIFD-PKCLDEFPNLKAFMCRFEALEKIAAYLQSDQ 206 ++ +C+D P LK +M + ++A L S++ Sbjct: 178 PWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 219 >3W6N-A nrPDB Length = 364 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 5/52 (9%) Query: 15 RGLAHAIR--LLLEFTDTSYEEKRYTCGEAPDYDRSQW---LDVKFKLDLDF 61 RG R L+L+ S E+KR T GE + +W L K KL DF Sbjct: 55 RGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDF 106 >4BEJ-A nrPDB Length = 617 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 5/52 (9%) Query: 15 RGLAHAIR--LLLEFTDTSYEEKRYTCGEAPDYDRSQW---LDVKFKLDLDF 61 RG R L+L+ S E+KR T GE + +W L K KL DF Sbjct: 60 RGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDF 111 >4IKD-A nrPDB Length = 172 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 59 LDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEK 98 L P + + G++ +T S+AILRY + CG +EE+ Sbjct: 124 LSVPEIEACVQGRSTMTVSDAILRYAM---SNCGWAQEER 160 >1AW9-A nrPDB Length = 216 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 49/115 (42%), Gaps = 14/115 (12%) Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKHNMCG----ETEEEKIRVDI-IENQVMDFRTQ- 114 F +P L+DG + +S AI RYIA K+ G ++++ +E + F Sbjct: 51 FGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNA 110 Query: 115 -------LIR-LCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVD 161 L+R L + + ++ E+L L + L + + AG++ T D Sbjct: 111 SPLVFQLLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLAD 165 >5A5K-A nrPDB Length = 212 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 18/120 (15%) Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKHNMCG----ETEEEKIR---VDIIENQVMDFR- 112 F +P DG K+ +S AI +YIA ++ G +T+ + I + I QV D + Sbjct: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 Query: 113 ---------TQLIRLCYS-SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDF 162 Q+ + Y + E + + +L L + L +F + AGE T D Sbjct: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 >5WP9-A nrPDB Length = 710 Score = 28.1 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 3/42 (7%) Query: 23 LLLEFTDTSYEEKRYTCGEAPDYDRSQW---LDVKFKLDLDF 61 L+L+ S E+KR T GE + +W L K KL DF Sbjct: 63 LILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDF 104 >4PNG-A nrPDB Length = 229 Score = 27.7 bits (60), Expect = 3.6, Method: Compositional matrix adjust. Identities = 25/142 (17%), Positives = 54/142 (38%), Gaps = 9/142 (6%) Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLI------ 116 +P L D + I S+AI+ Y+ K+ + + + +Q + F + +I Sbjct: 60 TVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALR 119 Query: 117 ---RLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 + ++ + + + + FL + AG +LT DF + + Sbjct: 120 SITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEV 179 Query: 174 FDPKCLDEFPNLKAFMCRFEAL 195 F ++P + A+ R + L Sbjct: 180 FVKVDTTKYPRIAAWFKRLQKL 201 >2C3Q-A nrPDB Length = 247 Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 44 DYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNM 90 D + Q L F +P L DG +T+S AIL Y+ RK+ + Sbjct: 41 DLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKV 87 >3UDO-A nrPDB Length = 361 Score = 27.3 bits (59), Expect = 6.0, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%) Query: 80 ILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD 123 IL +IA+K+N E E KI I+ + + ++LC SD Sbjct: 28 ILTFIAQKYNFSFELNEAKIGGASIDAYGVALSDETLKLCEQSD 71 >3VIB-A nrPDB Length = 210 Score = 26.9 bits (58), Expect = 6.2, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Query: 45 YDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDII 104 ++R Q D+ +K F N+ +L K + T+ NA + IARKH + + + + Sbjct: 96 FERLQSNDIHYK----FHNILFL---KCEHTEQNAAVIAIARKHQAIWREKITAVLTEAV 148 Query: 105 ENQ 107 ENQ Sbjct: 149 ENQ 151 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3GTU-B nrPDB 328 9e-91 4GTU-A nrPDB 311 1e-85 1XWK-A nrPDB 309 5e-85 2DC5-A nrPDB 309 7e-85 1B4P-A nrPDB 303 4e-83 1HNA-A nrPDB 303 5e-83 5FWG-A nrPDB 302 8e-83 1GSU-A nrPDB 282 9e-77 2FHE-A nrPDB 272 6e-74 5AN1-A nrPDB 264 2e-71 4Q5Q-A nrPDB 255 1e-68 2WRT-A nrPDB 253 4e-68 1FHE-A nrPDB 247 2e-66 2GSR-A nrPDB 247 2e-66 2GLR-A nrPDB 246 5e-66 1F3B-A nrPDB 242 8e-65 5D73-A nrPDB 241 1e-64 1B8X-A nrPDB 240 4e-64 2VCT-A nrPDB 240 5e-64 2VCV-A nrPDB 240 5e-64 1PL2-A nrPDB 239 9e-64 1BG5-A nrPDB 237 2e-63 1DUG-A nrPDB 237 3e-63 3I6A-A nrPDB 237 4e-63 18GS-A nrPDB 235 1e-62 1B48-A nrPDB 230 5e-61 5LCZ-A nrPDB 229 6e-61 1TU7-A nrPDB 227 2e-60 4WR5-A nrPDB 227 4e-60 1EV4-A nrPDB 225 8e-60 1VF1-A nrPDB 225 1e-59 3KXO-A nrPDB 212 7e-56 5Y9Z-A nrPDB 208 2e-54 2AAW-A nrPDB 204 2e-53 1GUL-A nrPDB 202 1e-52 1GSQ-A nrPDB 195 1e-50 4Q5R-A nrPDB 194 3e-50 1ZL9-A nrPDB 190 3e-49 4Q5F-A nrPDB 189 6e-49 1M0U-A nrPDB 181 2e-46 2CA8-A nrPDB 171 2e-43 1U3I-A nrPDB 170 4e-43 2WDU-A nrPDB 169 8e-43 1YQ1-A nrPDB 169 1e-42 2HNL-A nrPDB 160 4e-40 5F07-A nrPDB 106 6e-24 6F05-A nrPDB 94 4e-20 Sequences not found previously or not previously below threshold: 1AXD-A nrPDB 92 1e-19 5EY6-A nrPDB 80 7e-16 4PNG-A nrPDB 80 9e-16 5F06-A nrPDB 78 2e-15 1AW9-A nrPDB 77 7e-15 4YH2-A nrPDB 73 6e-14 5A5K-A nrPDB 73 9e-14 3VWX-A nrPDB 73 1e-13 4RI7-A nrPDB 73 1e-13 2GDR-A nrPDB 71 3e-13 4MPF-A nrPDB 71 4e-13 5ZWP-A nrPDB 71 5e-13 3UAR-A nrPDB 70 7e-13 2C3Q-A nrPDB 70 1e-12 3LSZ-A nrPDB 70 1e-12 1F2E-A nrPDB 67 5e-12 1PN9-A nrPDB 66 2e-11 2PMT-A nrPDB 65 2e-11 1JLV-A nrPDB 65 3e-11 3MAK-A nrPDB 64 6e-11 5F05-A nrPDB 62 2e-10 2IL3-A nrPDB 61 3e-10 2CZ2-A nrPDB 60 6e-10 3TOT-A nrPDB 60 8e-10 3IBH-A nrPDB 60 9e-10 4IKH-A nrPDB 60 1e-09 2PVQ-A nrPDB 59 1e-09 3M3M-A nrPDB 59 1e-09 5F0G-A nrPDB 59 2e-09 1V2A-A nrPDB 58 2e-09 3LFL-A nrPDB 58 2e-09 1FW1-A nrPDB 58 3e-09 3M8N-A nrPDB 58 3e-09 3UBL-A nrPDB 57 6e-09 5F8B-A nrPDB 57 7e-09 1N2A-A nrPDB 56 1e-08 4MDC-A nrPDB 55 4e-08 3GH6-A nrPDB 54 6e-08 3GX0-A nrPDB 52 2e-07 4G0L-A nrPDB 52 2e-07 3PR8-A nrPDB 52 2e-07 4PXO-A nrPDB 48 3e-06 4CHS-A nrPDB 48 4e-06 4FQU-A nrPDB 48 4e-06 1E6B-A nrPDB 47 8e-06 4J2F-A nrPDB 46 8e-06 5NR1-A nrPDB 46 9e-06 5J5N-A nrPDB 46 1e-05 4QQ7-A nrPDB 46 1e-05 4IGJ-A nrPDB 46 2e-05 4BVY-B nrPDB 45 3e-05 3PPU-A nrPDB 44 4e-05 2VO4-A nrPDB 44 4e-05 4USS-A nrPDB 44 5e-05 2JL4-A nrPDB 42 2e-04 6GCB-A nrPDB 42 2e-04 4MK3-A nrPDB 42 2e-04 6GZF-A nrPDB 41 3e-04 6GC9-A nrPDB 41 3e-04 4PTS-A nrPDB 41 4e-04 3C8E-A nrPDB 41 5e-04 5LOL-A nrPDB 40 0.001 3RBT-A nrPDB 39 0.001 5ELG-A nrPDB 38 0.005 3M1G-A nrPDB 38 0.005 5G5A-A nrPDB 37 0.006 3IR4-A nrPDB 37 0.008 6EP7-A nrPDB 36 0.014 5ECL-B nrPDB 35 0.027 5E32-A nrPDB 34 0.048 3NIV-A nrPDB 34 0.059 1GWC-A nrPDB 34 0.066 3BBY-A nrPDB 33 0.15 2JZR-A nrPDB 32 0.24 5N9U-A nrPDB 32 0.26 4J15-A nrPDB 31 0.32 6AIY-A nrPDB 31 0.49 2PAR-A nrPDB 31 0.53 1G6W-A nrPDB 31 0.54 5LKB-A nrPDB 31 0.55 3FQJ-A nrPDB 31 0.58 2IWR-A nrPDB 30 0.61 2YV7-A nrPDB 30 0.64 6JWK-A nrPDB 30 0.65 4KH5-A nrPDB 30 0.70 4BWG-A nrPDB 30 0.88 5KOD-A nrPDB 30 0.96 5HSX-A nrPDB 30 1.3 5KEU-A nrPDB 29 1.6 4K0G-A nrPDB 29 2.1 4JUK-A nrPDB 29 2.2 4CZI-A nrPDB 28 2.7 2H30-A nrPDB 28 3.3 6A0Z-A nrPDB 28 3.4 3ADR-A nrPDB 28 4.1 4BGZ-A nrPDB 28 4.3 2CYA-A nrPDB 28 4.5 1NX8-A nrPDB 28 5.0 4KWM-A nrPDB 27 5.7 5WP9-A nrPDB 27 7.0 4BEJ-A nrPDB 27 7.0 3W6N-A nrPDB 27 7.0 5Y7I-A nrPDB 26 9.1 2KEP-A nrPDB 26 9.3 2X49-A nrPDB 26 9.3 4G74-A nrPDB 26 9.5 >3GTU-B nrPDB Length = 224 Score = 328 bits (842), Expect = 9e-91, Method: Composition-based stats. Identities = 224/224 (100%), Positives = 224/224 (100%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF Sbjct: 1 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 60 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS Sbjct: 61 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 120 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE Sbjct: 121 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 180 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC 225 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC Sbjct: 181 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC 224 >4GTU-A nrPDB Length = 217 Score = 311 bits (798), Expect = 1e-85, Method: Composition-based stats. Identities = 157/217 (72%), Positives = 183/217 (84%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 SM LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 1 SMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 YL+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL R+CYS D E Sbjct: 61 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFE 120 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 KLKP+YLEELP ++ FS FLGK WF G+K+TFVDFL YD+LD +RIF+P CLD FPNL Sbjct: 121 KLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNL 180 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 K F+ RFE LEKI+AY++S +F P+ ++A WGNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1XWK-A nrPDB Length = 218 Score = 309 bits (793), Expect = 5e-85, Method: Composition-based stats. Identities = 158/218 (72%), Positives = 185/218 (84%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 M+LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNL Sbjct: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 PYL+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL +CY+ + Sbjct: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPN 184 EKLKP+YLEELP +LK +S FLGK WFAG K+TFVDFL YD+LD +RIF+PKCLD FPN Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 Query: 185 LKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 LK F+ RFE LEKI+AY++S +F P+ +KMA WGNK Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >2DC5-A nrPDB Length = 231 Score = 309 bits (791), Expect = 7e-85, Method: Composition-based stats. Identities = 148/220 (67%), Positives = 184/220 (83%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 S M LGYWDIRGLAHAIRL LE+TD+SYEEKRYT G+APDYD+SQWL+ KFKL LDF Sbjct: 5 SSGMPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDF 64 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 PNLPYL+DG +KITQSNAILRY+ RKHN+CGETEEE+IRVDI+ENQ+MD R L RLCY+ Sbjct: 65 PNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYN 124 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 +D EKLKP YLE+LPG ++ +S FLGK WFAG+K+TFVDF+ YD+L++N++F+ KCLD Sbjct: 125 ADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDA 184 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 FPNLK F+ RFE L+KI+ Y+++ +F P+ KMA WG+ Sbjct: 185 FPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >1B4P-A nrPDB Length = 217 Score = 303 bits (777), Expect = 4e-83, Method: Composition-based stats. Identities = 146/217 (67%), Positives = 178/217 (82%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 YL+DG KITQSNAI+RY+ARKH++CGETEEE+IRVD++ENQ MD R QL +CYS D E Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFE 120 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 + KP+YLE LP ++K +S FLGK WFAG K+T+VDFL YD+LDQ+RIF+PKCLD FPNL Sbjct: 121 RKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNL 180 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 K F+ RFE L+KI+ Y++S +F PI KMA W K Sbjct: 181 KDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >1HNA-A nrPDB Length = 217 Score = 303 bits (775), Expect = 5e-83, Method: Composition-based stats. Identities = 148/217 (68%), Positives = 182/217 (83%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 M LGYW+IRGLAH+IRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 YL+DG +KITQSNAILRYIARKHN+CGE+E+E+IR DI+ENQ MD R QL +LCY D E Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFE 120 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 KLKP+YL+ LP LK +S FLGK WF G+K+TFVDF+ YD+L++N++F+P CLD FPNL Sbjct: 121 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 180 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 K F+ RFE LEKI+AY++S +F P+ KMA +GNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >5FWG-A nrPDB Length = 217 Score = 302 bits (773), Expect = 8e-83, Method: Composition-based stats. Identities = 147/217 (67%), Positives = 182/217 (83%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 YL+DG KITQSNAI+RY+ARKH++CGETEEE+IR DI+ENQVMD R QLI LCY+ D E Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 120 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 K KP++L+ +P ++K +S FLGK WFAG+K+T+VDFL YDILDQ IF+PKCLD FPNL Sbjct: 121 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 180 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 K F+ RFE L+KI+AY++S ++ PI +K+AQW NK Sbjct: 181 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >1GSU-A nrPDB Length = 219 Score = 282 bits (722), Expect = 9e-77, Method: Composition-based stats. Identities = 143/215 (66%), Positives = 166/215 (77%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 LGYWDIRGLAHAIRLLLE+T+T Y+E+RY G APD+D S W + K KL LDFPNLPYL Sbjct: 3 TLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYL 62 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 +DG K+TQSNAILRYIARKHNMCGETE EK RVD++EN +MD R RLCYS D EKL Sbjct: 63 IDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEKL 122 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKA 187 KP YLE+LPG+L+Q S FLG SWF G+KLTFVDFL YD+LDQ R+F P C + NL Sbjct: 123 KPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLSQ 182 Query: 188 FMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 F+ RFEALEKI+AY++S +F K PI A W NK Sbjct: 183 FLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >2FHE-A nrPDB Length = 216 Score = 272 bits (697), Expect = 6e-74, Method: Composition-based stats. Identities = 102/214 (47%), Positives = 133/214 (62%), Gaps = 5/214 (2%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 LGYW IRGL +RLLLE+ YEE+ Y + +W KF+L LD PNLPY Sbjct: 3 KLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDG-----EKWFSKKFELGLDLPNLPYY 57 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 +D K K+TQS AILRYIA KH M G T EE+ RV +IE +D R + R+ Y E+L Sbjct: 58 IDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFEQL 117 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKA 187 K YL++LP +K +S FLGK + G ++ VDF+ Y+ LD R +P CLD FPNL+ Sbjct: 118 KEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNLQQ 177 Query: 188 FMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 FM R EAL I AY++S++F K P+N AQ+G Sbjct: 178 FMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >5AN1-A nrPDB Length = 219 Score = 264 bits (675), Expect = 2e-71, Method: Composition-based stats. Identities = 115/213 (53%), Positives = 143/213 (67%), Gaps = 2/213 (0%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 VLGYW R L IRL+L +T T +EEK Y G+APDYD+S+WL VKFKL L FPNLPY Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 +DG KITQS AI+RY+ARKH +CG T EE +R D+IE Q+ D + Y +H + Sbjct: 63 YIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EHYE 120 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 K Y LP +L+Q+S FLG WFAG+KLT++DFL Y+I DQ+ D CLD F NL+ Sbjct: 121 QKDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKNLQ 180 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQW 219 AF RFE LE I Y+ S +F K PI NK AQ+ Sbjct: 181 AFQKRFEDLEAIKKYMASPKFLKKPICNKYAQF 213 >4Q5Q-A nrPDB Length = 219 Score = 255 bits (651), Expect = 1e-68, Method: Composition-based stats. Identities = 93/218 (42%), Positives = 139/218 (63%), Gaps = 2/218 (0%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S +LGYWDIRG A IRLLL ++ + +KRY G APD+DRS+WL+ KF L LDFPNL Sbjct: 2 SQPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNL 61 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 PY +DG K+TQ+ AILRY+ RK+ + G + E+IR+ + E Q D +IR+CY ++ Sbjct: 62 PYYIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANC 121 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPN 184 +KLKP YL+ LP LK S F+G+ ++ AG +++VDF Y+ L ++ P+ +F N Sbjct: 122 DKLKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFEN 181 Query: 185 LKAFMCRFEALEKIAAYLQSDQFC--KMPINNKMAQWG 220 LK ++ R E+L +++ Y++ Q P + A + Sbjct: 182 LKRYVERMESLPRVSDYIKKQQPKTFNAPTSKWNASYA 219 >2WRT-A nrPDB Length = 218 Score = 253 bits (647), Expect = 4e-68, Method: Composition-based stats. Identities = 100/217 (46%), Positives = 134/217 (61%), Gaps = 5/217 (2%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 LGYW IRGL +RLLLE+ YEE Y + R +WL KF + LD PNL Sbjct: 1 MPAKLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDD-----REKWLGDKFNMGLDLPNL 55 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 PY +D K K+TQS AI+RYIA KH M G T EE+ R+ +IE MD R +R+CY+ Sbjct: 56 PYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKF 115 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPN 184 E++K YL+ELP LK +S FLG + G ++ VDF+ Y+ LD R P+CL++FP Sbjct: 116 EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 185 LKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 LK F R E L KI AY++S++F K P+N+ +A +G Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >1FHE-A nrPDB Length = 217 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 100/213 (46%), Positives = 131/213 (61%), Gaps = 5/213 (2%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 LGYW +RGLA +RL LE+ YEE Y + R +W+ KF + LD PNLPY Sbjct: 3 KLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDD-----REKWMSEKFNMGLDLPNLPYY 57 Query: 68 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKL 127 +D K K+TQS AI+RYIA KH M G T EE+ R+ +IE MD R R+CY+ E++ Sbjct: 58 IDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFEEV 117 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKA 187 K +Y++ELP LK +S FLG + G ++ VDF+ Y+ LD R P CLDEFP LK Sbjct: 118 KEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKLKE 177 Query: 188 FMCRFEALEKIAAYLQSDQFCKMPINNKMAQWG 220 F R EAL KI AY++S +F K P+N A +G Sbjct: 178 FKSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >2GSR-A nrPDB Length = 207 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 70/217 (32%), Positives = 110/217 (50%), Gaps = 15/217 (6%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 + Y+ +RG A+R+LL D S++E+ T P K F LP Sbjct: 2 PYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWPPL----------KPSCLFRQLP 51 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 DG + QSNAILR++ R + G+ ++E VD++ + V D R + L Y+ ++E Sbjct: 52 KFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYE 110 Query: 126 KLKPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 K +Y++ELP LK F L G ++ G +++F D+ D+L +++ +P CLD Sbjct: 111 AGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDA 170 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 FP L A++ R A KI A+L S + PIN Q Sbjct: 171 FPLLSAYVARLSARPKIKAFLASPEHVNRPINGNGKQ 207 >2GLR-A nrPDB Length = 209 Score = 246 bits (629), Expect = 5e-66, Method: Composition-based stats. Identities = 67/217 (30%), Positives = 110/217 (50%), Gaps = 13/217 (5%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 + Y+ +RG A+R+LL S++E+ T W+ K + LP Sbjct: 2 PYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLP 53 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 DG + QSNAILR++ R + G+ + E ++D++ + V D R + + L Y+ ++E Sbjct: 54 KFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYE 112 Query: 126 KLKPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 K Y++ LPG LK F L G ++ G++++F D+ D+L +++ P CLD Sbjct: 113 NGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 172 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 FP L A++ R A KI A+L S + PIN Q Sbjct: 173 FPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ 209 >1F3B-A nrPDB Length = 222 Score = 242 bits (618), Expect = 8e-65, Method: Composition-based stats. Identities = 59/226 (26%), Positives = 92/226 (40%), Gaps = 22/226 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 VL Y++ RG IR LL +EEK +K +L F +P Sbjct: 4 PVLHYFNARGRMECIRWLLAAAGVEFEEKFIQS-------PEDLEKLKKDGNLMFDQVPM 56 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH-- 124 + K+ Q+ AIL YIA K+++ G+ +E+ +D+ ++D + +L Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQR 116 Query: 125 --------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 ++ K +YL LK + G +LT VD ++L FD Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLEVLLYVEEFDA 171 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP LKAF R +L + +LQ K P++ K Q K Sbjct: 172 SLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARK 217 >5D73-A nrPDB Length = 208 Score = 241 bits (616), Expect = 1e-64, Method: Composition-based stats. Identities = 72/218 (33%), Positives = 107/218 (49%), Gaps = 14/218 (6%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S L Y+ IRGLA IRL+L + + R + P K F L Sbjct: 1 MSYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWPS----------MKSHFHFGQL 50 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 P L DG ++I QS AILR++ARKHN+ G E E +D+ V D T+ ++ Y + Sbjct: 51 PCLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYD 110 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFS----WFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 + + LP +L +F L + GEK+++VDF+ ++ LD ++I DP CLD Sbjct: 111 TEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLD 170 Query: 181 EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 +FP LKA+ R E + Y + K+P+N Q Sbjct: 171 KFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPVNGNGKQ 208 >1B8X-A nrPDB Length = 280 Score = 240 bits (612), Expect = 4e-64, Method: Composition-based stats. Identities = 92/216 (42%), Positives = 125/216 (57%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >2VCT-A nrPDB Length = 222 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 89/230 (38%), Gaps = 22/230 (9%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 L Y +IRG +IR LL +EEK E D R+ L F Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQ 53 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P + K+ Q+ AIL YIA K+N+ G+ +EK +D+ + D ++ L ++ Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQ 113 Query: 123 DH----------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNR 172 EK K +Y LK + G KL+ D ++L Sbjct: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVE 168 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 D + FP LKA R L + +LQ K P++ K + K Sbjct: 169 ELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 >2VCV-A nrPDB Length = 222 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 55/226 (24%), Positives = 84/226 (37%), Gaps = 22/226 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L Y++ RG IR LL +EEK E R+ L F +P Sbjct: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRND-------GSLMFQQVPM 57 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH-- 124 + K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D ++ L Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK 117 Query: 125 --------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 EK K +Y L+ + G KL+ D ++L D Sbjct: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDS 172 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 + FP LKA R L + +LQ K P + K + K Sbjct: 173 SLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 >1PL2-A nrPDB Length = 222 Score = 239 bits (609), Expect = 9e-64, Method: Composition-based stats. Identities = 56/230 (24%), Positives = 86/230 (37%), Gaps = 22/230 (9%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 L Y++ RG + R LL +EEK E D R+ L F Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQ 53 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P + K+ Q AIL YIA K+N+ G+ +E+ +D+ + D ++ L Sbjct: 54 QVPMVEIDGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCP 113 Query: 123 DH----------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNR 172 EK+K +Y LK + G KL+ D ++L Sbjct: 114 PEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVE 168 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 D + FP LKA R L + +LQ K P++ K + K Sbjct: 169 ELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARK 218 >1BG5-A nrPDB Length = 254 Score = 237 bits (606), Expect = 2e-63, Method: Composition-based stats. Identities = 92/217 (42%), Positives = 125/217 (57%), Gaps = 5/217 (2%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNL Sbjct: 1 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNL 55 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 PY +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D Sbjct: 56 PYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDF 115 Query: 125 EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPN 184 E LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP Sbjct: 116 ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 185 LKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 L F R EA+ +I YL+S ++ P+ A +G Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 212 >1DUG-A nrPDB Length = 234 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 92/216 (42%), Positives = 125/216 (57%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE+ + YEE Y E +W + KF+L L+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+RYIA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L ++ G+ +T DF+ YD LD DP CLD FP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >3I6A-A nrPDB Length = 222 Score = 237 bits (604), Expect = 4e-63, Method: Composition-based stats. Identities = 55/219 (25%), Positives = 83/219 (37%), Gaps = 22/219 (10%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 L Y++ RG + R LL +EEK E D R+ L F Sbjct: 1 MAEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQ 53 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P + K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D +I L + Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCP 113 Query: 123 DH----------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNR 172 EK+K +Y LK + G KL+ D ++L Sbjct: 114 PEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVE 168 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 D + FP LKA R L + +LQ K P Sbjct: 169 ELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >18GS-A nrPDB Length = 210 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 68/217 (31%), Positives = 111/217 (51%), Gaps = 13/217 (5%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 + Y+ +RG A+R+LL S++E+ T W + K + LP Sbjct: 3 PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 DG + QSN ILR++ R + G+ ++E VD++ + V D R + I L Y+ ++E Sbjct: 55 KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113 Query: 126 KLKPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181 K Y++ LPGQLK F L G ++ G++++F D+ D+L + + P CLD Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173 Query: 182 FPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 FP L A++ R A K+ A+L S ++ +PIN Q Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 210 >1B48-A nrPDB Length = 221 Score = 230 bits (586), Expect = 5e-61, Method: Composition-based stats. Identities = 50/222 (22%), Positives = 89/222 (40%), Gaps = 22/222 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L Y++ RG +IR LL +EE+ R Q+ ++ L F +P Sbjct: 4 PKLYYFNGRGRMESIRWLLAAAGVEFEEEFLET-------REQYEKMQKDGHLLFGQVPL 56 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 + +TQ+ AIL Y+A K+N+ G+ +E++R+D+ + D + + + EK Sbjct: 57 VEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEK 116 Query: 127 L----------KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 K +Y LK ++ G +L++ D + + Sbjct: 117 EESYDLILSRAKTRYFPVFEKILKDHGE-----AFLVGNQLSWADIQLLEAILMVEELSA 171 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 L +FP L+AF R + I +LQ K P + + Sbjct: 172 PVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVE 213 >5LCZ-A nrPDB Length = 222 Score = 229 bits (585), Expect = 6e-61, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 22/230 (9%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 L Y++ RG + R LL +EEK E D R+ L F Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQ 53 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P + K+ Q+ AIL YIA K+N+ G+ +E+ +D+ ++D +I+L Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICP 113 Query: 123 DH----------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNR 172 ++ K +YL LK + G +LT VD ++L Sbjct: 114 PDQREAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLELLLYVE 168 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 FD L FP LKAF R +L + +LQ K ++ K + K Sbjct: 169 EFDASLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARK 218 >1TU7-A nrPDB Length = 208 Score = 227 bits (580), Expect = 2e-60, Method: Composition-based stats. Identities = 71/218 (32%), Positives = 104/218 (47%), Gaps = 14/218 (6%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S L Y+ IRGLA IRL L D + + R + K F L Sbjct: 1 MSYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIAKDDFSS----------IKSQFQFGQL 50 Query: 65 PYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH 124 P L DG +I QS AILR++ARK+N+ GE E E +D+ V D + R+ Y + Sbjct: 51 PCLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYE 110 Query: 125 EKLKPQYLEELPGQLKQFSMFLG----KFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 + P LPG+L +F L + G+K+++ D+ ++ LD ++I DP CLD Sbjct: 111 TEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLD 170 Query: 181 EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQ 218 +FP LK F R + K+ Y + K+P+N Q Sbjct: 171 KFPLLKVFHQRMKDRPKLKEYCEKRDAAKVPVNGNGKQ 208 >4WR5-A nrPDB Length = 244 Score = 227 bits (578), Expect = 4e-60, Method: Composition-based stats. Identities = 87/216 (40%), Positives = 121/216 (56%), Gaps = 5/216 (2%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S +LGYW I+GL RLLLE + ++Y + +W + KF+L L+FPNLP Sbjct: 26 SPILGYWKIKGLVQPTRLLLEXLE-----EKYEEHLXERDEGDKWRNKKFELGLEFPNLP 80 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 Y +DG K+TQS AI+R IA KHNM G +E+ + ++E V+D R + R+ YS D E Sbjct: 81 YXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 140 Query: 126 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 185 LK +L +LP LK F L + G+ +T DF+ YD LD DP CLD FP L Sbjct: 141 TLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKL 200 Query: 186 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 F R EA+ +I YL+S ++ P+ A +G Sbjct: 201 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 236 >1EV4-A nrPDB Length = 221 Score = 225 bits (575), Expect = 8e-60, Method: Composition-based stats. Identities = 59/226 (26%), Positives = 94/226 (41%), Gaps = 22/226 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 VL Y++ RG IR LL ++EK +K +L F +P Sbjct: 4 PVLHYFNARGRMECIRFLLAAAGVEFDEKFIQS-------PEDLEKLKKDGNLMFDQVPM 56 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 + K+ Q+ AIL YIA K+++ G+ +E+ +D+ ++D +++L +K Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQK 116 Query: 127 L----------KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 K +YL LK + G KLT VD ++L FD Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNKLTRVDIHLLELLLYVEEFDA 171 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP LKAF R +L + +LQ K+P++ K + K Sbjct: 172 SLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARK 217 >1VF1-A nrPDB Length = 229 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 51/230 (22%), Positives = 88/230 (38%), Gaps = 22/230 (9%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 + VL Y++ RG +IR LL +EE R Q+ + L F Sbjct: 1 MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLET-------REQYEKLLQSGILMFQ 53 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P + K+ Q+ AIL YIA K+N+ G+ +E+ +D+ D L+ + S Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLS 113 Query: 123 DHEKLK----------PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNR 172 +K+K +Y LK + G +L++ D + + Sbjct: 114 AEDKVKQCAFVVEKATSRYFPAYEKVLKDHGQ-----DFLVGNRLSWADIHLLEAILMVE 168 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 L FP L+AF R ++ I +L K ++K + + Sbjct: 169 EKKSDALSGFPLLQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRR 218 >3KXO-A nrPDB Length = 202 Score = 212 bits (541), Expect = 7e-56, Method: Composition-based stats. Identities = 53/209 (25%), Positives = 89/209 (42%), Gaps = 18/209 (8%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 + L Y+++RG A IR + + D YE+ R + P+ K L F +P Sbjct: 6 NYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIP 55 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 L + QS AI RY+ + ++ G TE E+ VD I + + DF + ++ + Sbjct: 56 ILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCF---PWAEKKQ 112 Query: 126 KLKPQYLEEL-----PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 +K Q EL P ++ +LG W G +T+ DF +F P LD Sbjct: 113 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 172 Query: 181 EFPNLKAFMCRFEALEKIAAYLQSDQFCK 209 P L + +A+ +A +++ K Sbjct: 173 NHPRLVTLRKKVQAIPAVANWIKRRPQTK 201 >5Y9Z-A nrPDB Length = 199 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 54/209 (25%), Positives = 94/209 (44%), Gaps = 18/209 (8%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 + L Y+++RG A IR + + D YE+ R + P K K L F +P Sbjct: 3 NYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGKIP 52 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 125 L + QS AI RY+ + ++ G+TE E+ +VD + + + DF + ++ +++ Sbjct: 53 VLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLF---PWAEENQ 109 Query: 126 KLKPQYLEEL-----PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 LK + +L P LK +LG WF G +T+ DF + P L Sbjct: 110 DLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLG 169 Query: 181 EFPNLKAFMCRFEALEKIAAYLQSDQFCK 209 +P L + + +A+ I+A++ K Sbjct: 170 IYPRLVSLRNKVQAIPAISAWILKRPQTK 198 >2AAW-A nrPDB Length = 222 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 59/213 (27%), Positives = 92/213 (43%), Gaps = 13/213 (6%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 S ++VL Y+D RG A IRL+ + Y +KR+ ++ + K + D F Sbjct: 11 SMGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGD---AFVEFKNFKKEKDTPF 67 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 +P L G + QS AI+RY+++K+N+CGE+E + D+I V D + Sbjct: 68 EQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLF 127 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFLGKFS--------WFAGEKLTFVDFLTYDILDQNRI 173 +E E+LP F L K +F G LT+ D +++ D Sbjct: 128 KQNETT--FLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIET 185 Query: 174 FDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQ 206 P L FP LKA L I Y+ + + Sbjct: 186 KYPSSLKNFPLLKAHNEFISNLPNIKNYITNRK 218 >1GUL-A nrPDB Length = 222 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 43/215 (20%), Positives = 81/215 (37%), Gaps = 22/215 (10%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L Y + RG ++R +L ++E+ + Q ++ L F +P Sbjct: 5 PKLHYPNGRGRMESVRWVLAAAGVEFDEEFLET-------KEQLYKLQDGNHLLFQQVPM 57 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 + K+ Q+ +IL YIA KHN+ G+ +E+ +D+ +D LI + ++ Sbjct: 58 VEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQ 117 Query: 127 LKP----------QYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 K +Y L+ S+ G +L+ D + + P Sbjct: 118 QKEVVNMAQKAIIRYFPVFEKILRGHGQ-----SFLVGNQLSLADVILLQTILALEEKIP 172 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 L FP L+ + + + I +L+ K P Sbjct: 173 NILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPP 207 >1GSQ-A nrPDB Length = 202 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 25/214 (11%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L Y+ + G A R +L + ++ + P+ + + + +P Sbjct: 3 YTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNA----------MPV 52 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L K++QS I R++AR+ + G+T EK RVD I + D ++++ ++ + K Sbjct: 53 LDIDGTKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAK 112 Query: 127 LKPQYLEELPGQLKQFSMFL--------GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178 Q + K+ + FL G +F G +T D Y L+ P+ Sbjct: 113 EAVQ--QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPEL 170 Query: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPI 212 L + P + A R KIAAYL+ K P+ Sbjct: 171 LKDCPKIVALRKRVAECPKIAAYLK-----KRPV 199 >4Q5R-A nrPDB Length = 204 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 55/211 (26%), Positives = 90/211 (42%), Gaps = 16/211 (7%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 S L Y ++ L IR LL + + +E+ R+ G+ P+ K + F Sbjct: 1 MAPSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNL----------KPSMPFG 50 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 P L + QS AI RY+ ++ + G+ + E + +D+I + + DFR + Y + Sbjct: 51 KTPVLEIDGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDA 110 Query: 123 DH----EKLKPQYLEELPGQLKQFSMFL-GKFSWFAGEKLTFVDFLTYDILDQ-NRIFDP 176 D +K P E +P K+F + + A KLT+ DF ILD N + Sbjct: 111 DENSKQKKWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKE 170 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQF 207 + PNLKA + L I A++ Sbjct: 171 DLVANQPNLKALREKVLGLPAIKAWVAKRPP 201 >1ZL9-A nrPDB Length = 207 Score = 190 bits (484), Expect = 3e-49, Method: Composition-based stats. Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 18/209 (8%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y++ RG R + + YE+ R T + QW +K F LP Sbjct: 3 SYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQLP 54 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY----- 120 +L K+ QS+AI R++AR+ + G+T E+ +V+ + +Q D+ ++ Y Sbjct: 55 FLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGF 114 Query: 121 -SSDHEKLKPQ-YLEELPGQLKQFSMFL--GKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 D E LK +L FL + G+ LT++D + I Sbjct: 115 GPGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDL-AIAQHSADLIAKG 173 Query: 177 KCLDEFPNLKAFMCRFEALEKIAAYLQSD 205 +FP LKA + +A+ +I ++++ Sbjct: 174 GDFSKFPELKAHAEKIQAIPQIKKWIETR 202 >4Q5F-A nrPDB Length = 218 Score = 189 bits (481), Expect = 6e-49, Method: Composition-based stats. Identities = 55/210 (26%), Positives = 83/210 (39%), Gaps = 21/210 (10%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 L Y+DIRGL RL+ +E+ R + P K F LP Sbjct: 15 QYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPAL----------KPKTPFGQLP 64 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY---SS 122 L + QS AI RY+ R+ + G+T E+ +VD I +Q DF +L R C+ + Sbjct: 65 LLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAEL-RPCFRVLAG 123 Query: 123 DHEKLKPQYLEELP-----GQLKQFSMFLGKFS--WFAGEKLTFVDFLTYDILDQNRIFD 175 E K + L+E+ L FL K + G+ +T+ D + D L Sbjct: 124 FEEGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLI 183 Query: 176 PKCLDEFPNLKAFMCRFEALEKIAAYLQSD 205 P L LK ++ L I ++ Sbjct: 184 PDFLSGHLQLKKYIEHVRELPNIKKWIAER 213 >1M0U-A nrPDB Length = 249 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 33/224 (14%) Query: 3 CESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP 62 + S L Y++++ LA +R L + + YE+ R T E P K + Sbjct: 46 IKHSYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWPAL----------KPTMPMG 95 Query: 63 NLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSS 122 +P L ++ QS ++ R++A+ +CG T E +++DI+ + + DFR ++ + Y Sbjct: 96 QMPVLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEP 155 Query: 123 DHE-----------KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQ- 170 + E ++ P YLE+L +K A KLT+ D I D Sbjct: 156 EDEIKEKKLVTLNAEVIPFYLEKLEQTVKD------NDGHLALGKLTWADVYFAGITDYM 209 Query: 171 NRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINN 214 N + L+ +P L+ + ALE I A+++ K P+ Sbjct: 210 NYMVKRDLLEPYPALRGVVDAVNALEPIKAWIE-----KRPVTE 248 >2CA8-A nrPDB Length = 211 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 93/219 (42%), Gaps = 33/219 (15%) Query: 1 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD 60 M+ + V+ Y++ RG A +IR+ L +YE++R + + P K K + Sbjct: 1 MTGDHIKVI-YFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIP 49 Query: 61 FPNLPYLLDGKNK-----ITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQL 115 LP + N + +S AI RY+A+KH+M G TEEE V+ + Q D + Sbjct: 50 GGRLPAVKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEY 109 Query: 116 IRLCYSSDHEKLK----------PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY 165 + + EK K P L+ + LK + L G+K+T D + Sbjct: 110 YKTLMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLA-----VGDKVTLADLVLI 164 Query: 166 DILDQNRIFDPKCL-DEFPNLKAFMCR-FEALEKIAAYL 202 ++D D + L ++P + + ++A YL Sbjct: 165 AVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYL 203 >1U3I-A nrPDB Length = 211 Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats. Identities = 54/218 (24%), Positives = 90/218 (41%), Gaps = 25/218 (11%) Query: 1 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD 60 M+ E V+ Y+D RG A +IR+ L YE++R + + P K K + Sbjct: 1 MAGEHIKVI-YFDGRGRAESIRMTLVAAGVDYEDERISFQDWP----------KIKPTIP 49 Query: 61 FPNLPYLLDGKNK-----ITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQL 115 LP + + + +S AI RY+A+KH+M GET+EE V+ + Q D + Sbjct: 50 GGRLPAVKVTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEY 109 Query: 116 IRLCYSSDHEKLKPQYLEELPGQLKQF-----SMFLGKFSWF-AGEKLTFVDFLTYDILD 169 + EK K E L G++ G G+K+T D + ++D Sbjct: 110 HKTLMKPQEEKEKITK-EILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVID 168 Query: 170 QNRIFDPKCL-DEFPNLKAFMCR-FEALEKIAAYLQSD 205 D L ++P + + ++A YL + Sbjct: 169 HVTDLDKGFLTGKYPEIHKHRENLLASSPRLAKYLSNR 206 >2WDU-A nrPDB Length = 211 Score = 169 bits (428), Expect = 8e-43, Method: Composition-based stats. Identities = 58/220 (26%), Positives = 87/220 (39%), Gaps = 24/220 (10%) Query: 4 ESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPN 63 + L Y+ RG A IRLLL +E+ ++T + P K L Sbjct: 3 KQHFKLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPT----------IKPTLPGGR 52 Query: 64 LPYLL----DGKNKITQ-SNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ---L 115 +P L DGK + Q S AI R +AR+ M GET+EE ++ I + D + + Sbjct: 53 VPLLDVTGPDGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTI 112 Query: 116 IRLCYSSDHEKLKPQYLEELPGQLKQFSMFL--GKFSWFAGEKLTFVDFLTYDILDQNRI 173 R K+K P LK S L AG ++T D + L Sbjct: 113 FRTPQGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVME 172 Query: 174 FDPKCLD-EFPNLKAFMCRF-EALEKIAAYLQSDQFCKMP 211 P L+ +FP L F + +++ YL+ + K P Sbjct: 173 TVPGFLEQKFPKLHEFHKSLPTSCSRLSEYLK--KRAKTP 210 >1YQ1-A nrPDB Length = 208 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 58/222 (26%), Positives = 89/222 (40%), Gaps = 28/222 (12%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 S L Y+ RGL IRLL +EE R + WLD+K + LP Sbjct: 3 SYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMNPDQ-------TWLDIKDSTPMK--QLP 53 Query: 66 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY----- 120 L ++ QS AILRY+ARK G+T EE+ VD + + DF + + Sbjct: 54 VLNIDGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSG 113 Query: 121 --SSDHEKLKPQYLEELPGQLKQFSMFLG-----KFSWFAGEKLTFVDFLTYDILDQNRI 173 + + EK + ++ LP + F++ G + G +TF D + D L + Sbjct: 114 KSAEEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKN 171 Query: 174 FDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNK 215 + EF L A + + I Y+ K P+ Sbjct: 172 YGLFDESEFTKLAALREKVNSYPGIKEYI-----AKRPVTEY 208 >2HNL-A nrPDB Length = 225 Score = 160 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 45/206 (21%), Positives = 89/206 (43%), Gaps = 20/206 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L Y++ RG A IRLL + SYE+ R T R +W +K + F ++P Sbjct: 28 YTLTYFNGRGRAEVIRLLFALANVSYEDNRIT--------RDEWKYLKPR--TPFGHVPM 77 Query: 67 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126 L N + +S+AI + + + G + E+ ++ + + + +LI + + K Sbjct: 78 LNVSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTK 137 Query: 127 LKPQYLEELPGQ-----LKQFSMFLGKF--SWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 K + L L ++ FL + G K++ D +++L + D L Sbjct: 138 -KAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMT--LDDEVKL 194 Query: 180 DEFPNLKAFMCRFEALEKIAAYLQSD 205 +E+P L +F+ + + I +++ Sbjct: 195 EEYPQLASFVNKIGQMPGIKEWIKKR 220 >5F07-A nrPDB Length = 213 Score = 106 bits (266), Expect = 6e-24, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 67/177 (37%), Gaps = 19/177 (10%) Query: 44 DYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKH-----NMCGETEEEK 98 D D + +F L F +P + DG K+ +S AI+RY A K+ N+ G T EEK Sbjct: 33 DLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEK 92 Query: 99 IRVD-IIENQVMDFRTQLIRLCY----------SSDHEKLKPQYLEELPGQLKQFSMFLG 147 VD +E + +F + + + D E ++ Y E+L L + L Sbjct: 93 ALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGDSELVR-TYEEKLEKVLDVYEKRLS 151 Query: 148 KFSWFAGEKLTFVDFLTYDI--LDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYL 202 K + AG+ T D N + + L A+ + + Sbjct: 152 KSKYLAGDSFTLADLSHLPATRYLVNEAGLGHLVKDRKKLNAWWEDISSRPAWKKLM 208 >6F05-A nrPDB Length = 215 Score = 94.2 bits (233), Expect = 4e-20, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 68/165 (41%), Gaps = 17/165 (10%) Query: 60 DFPNLPYLLDGKNKITQSNAILRYIARKH-----NMCGETEEEKIRVD-IIENQVMDFRT 113 F +P ++DG KI +S A++RY+A K+ ++ G+T E++ +V+ ++ + + Sbjct: 49 PFGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHP 108 Query: 114 QLIRLCY---------SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT 164 L+ L EKL + E+L G L + L K + AG+ ++ D Sbjct: 109 PLLNLTLHIMFASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAH 168 Query: 165 YDILDQNR--IFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQF 207 D I + + ++ A+ + + F Sbjct: 169 LPFTDYLVGPIGKAYMIKDRKHVSAWWDDISSRPAWKETVAKYSF 213 >1AXD-A nrPDB Length = 209 Score = 92.3 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 41/190 (21%), Positives = 68/190 (35%), Gaps = 20/190 (10%) Query: 25 LEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYI 84 LE + YE A + F +P L DG + +S AI +Y Sbjct: 21 LEEAGSDYEIVPINFATAEHKSPEHLVRN------PFGQVPALQDGDLYLFESRAICKYA 74 Query: 85 ARKHN---MCGETEEEKIRVD-IIENQVMDFRTQLIRLCYS---------SDHEKLKPQY 131 ARK+ + EE VD IE + + L + + + +K+ + Sbjct: 75 ARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDEN 134 Query: 132 LEELPGQLKQFSMFLGKFSWFAGEKLTFVDF-LTYDILDQNRIFDPKCLDEFPNLKAFMC 190 LE+L L+ + L K + AG+ L+ D L LD +P++KA+ Sbjct: 135 LEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATPYASVLDAYPHVKAWWS 194 Query: 191 RFEALEKIAA 200 + Sbjct: 195 GLMERPSVQK 204 >5EY6-A nrPDB Length = 217 Score = 80.0 bits (196), Expect = 7e-16, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 51/165 (30%), Gaps = 18/165 (10%) Query: 60 DFPNLPYLLDGKNKITQSNAILRYIARKH------NMCGETEEEKIRVDIIEN------- 106 F +P D + +S +I RY+ K+ + G E+ +D Sbjct: 51 PFGQVPAFQDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFG 110 Query: 107 ---QVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 + F+ + + Q E+L L + LG+ + AG++ TF D Sbjct: 111 PSSGALVFQLAFAPRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLS 170 Query: 164 TYDILDQ--NRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQ 206 D N N+ + E ++ + Sbjct: 171 HLPNGDYLVNATDKGHLFTSRENVGRWWNEISDRESWKKVIEMRK 215 >4PNG-A nrPDB Length = 229 Score = 80.0 bits (196), Expect = 9e-16, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 67/186 (36%), Gaps = 15/186 (8%) Query: 20 AIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNA 79 A++L L + YE + + +F +P L D + I S+A Sbjct: 23 AVKLTLAALEVPYE--FVEV----NTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHA 76 Query: 80 ILRYIARKHN----MCGETEEEKIRVDI---IENQV--MDFRTQLIRLCYSSDHEKLKPQ 130 I+ Y+ K+ + + ++ VD E+ V + + + ++ + + Sbjct: 77 IIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKE 136 Query: 131 YLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMC 190 + + FL + AG +LT DF + +F ++P + A+ Sbjct: 137 RYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFK 196 Query: 191 RFEALE 196 R + L Sbjct: 197 RLQKLP 202 >5F06-A nrPDB Length = 216 Score = 78.4 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 56/169 (33%), Gaps = 19/169 (11%) Query: 60 DFPNLPYLLDGKNKITQSNAILRYIARKHNMCG------ETEEEKIRVD-IIENQVMDFR 112 F +P L + + +S AI YIA K G E +E V E + + Sbjct: 49 PFGQIPALEEDDLTLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYN 108 Query: 113 TQLIRLCYS---------SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 + + + S + + +E+L L + L + AG+ + D Sbjct: 109 PAIAPIVFQFMVAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLH 168 Query: 164 TYDILDQNRIFDP--KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKM 210 + P ++E P++KA+ + + F K Sbjct: 169 HLP-YTYYLMKTPAASVVNERPHVKAWWEDISSRPAFKKVAEGMNFVKK 216 >1AW9-A nrPDB Length = 216 Score = 76.9 bits (188), Expect = 7e-15, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 58/167 (34%), Gaps = 15/167 (8%) Query: 60 DFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEE----EKIRVD-IIENQVMDFRTQ 114 F +P L+DG + +S AI RYIA K+ G +++ +E + F Sbjct: 50 PFGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPN 109 Query: 115 LIRLCYS---------SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY 165 L + + + ++ E+L L + L + + AG++ T D Sbjct: 110 ASPLVFQLLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHA 169 Query: 166 DILDQNRIF-DPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 L + P++KA+ A + + P Sbjct: 170 SYLLYLSKTPKAGLVAARPHVKAWWEAIVARPAFQKTVAAIPLPPPP 216 >4YH2-A nrPDB Length = 222 Score = 73.4 bits (179), Expect = 6e-14, Method: Composition-based stats. Identities = 34/187 (18%), Positives = 64/187 (34%), Gaps = 17/187 (9%) Query: 20 AIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNA 79 A++L L + +YE +P L D + I S+A Sbjct: 17 AVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKN------PQHTVPTLEDDGHYIWDSHA 70 Query: 80 ILRYIARKHN----MCGETEEEKIRVDI---IENQV---MDFRTQLIRLCYSSDHEKLKP 129 I+ Y+ K+ + + ++ VD E+ V R+ + + + K Sbjct: 71 IIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKE 130 Query: 130 QYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFM 189 +Y + FL + AG +LT DF + F ++P + A++ Sbjct: 131 RYDAIIE-IYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWI 189 Query: 190 CRFEALE 196 + E L Sbjct: 190 KKLEQLP 196 >5A5K-A nrPDB Length = 212 Score = 73.0 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 69/209 (33%), Gaps = 38/209 (18%) Query: 25 LEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYI 84 L + +E + + F F +P DG K+ +S AI +YI Sbjct: 22 LHEKNLDFELVHVELKDG------EHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYI 75 Query: 85 ARKH-----NMCGETEEE--KIRVDIIENQVMD----------FRTQLIRLCYS-SDHEK 126 A ++ N+ + + + I QV D Q+ + Y + E Sbjct: 76 AHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEA 135 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 + + +L L + L +F + AGE T D + L P K Sbjct: 136 VVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY--------LLGTPTKK 187 Query: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNK 215 F R ++ ++ + K P + K Sbjct: 188 LFTER----PRVNEWVA--EITKRPASEK 210 >3VWX-A nrPDB Length = 222 Score = 73.0 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 72/189 (38%), Gaps = 18/189 (9%) Query: 20 AIR---LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQ 76 +R L L+ + +E K A ++ ++L + +P L + + I Sbjct: 14 PVRACLLTLKALNLPFEYKVVNLF-AKEHLSEEYLKKNPQHT-----VPTLEEDGHLIWD 67 Query: 77 SNAILRYIARKHN----MCGETEEEKIRVD--IIENQVMDFRTQLIRLC---YSSDHEKL 127 S+AI+ Y+ K+ + + ++ VD + + F+ L + + + ++ Sbjct: 68 SHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQI 127 Query: 128 KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKA 187 ++ + FL + AG+ LT DF + F +FP L A Sbjct: 128 PQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSA 187 Query: 188 FMCRFEALE 196 ++ ++L Sbjct: 188 WLKSLQSLP 196 >4RI7-A nrPDB Length = 215 Score = 73.0 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 48/133 (36%), Gaps = 15/133 (11%) Query: 44 DYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKH------NMCGETEEE 97 D + + ++ F +P D + +S AI RYI K+ ++ G Sbjct: 36 DLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILS 95 Query: 98 KIRVDIIENQ--------VMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKF 149 K +D D L+ E L + +++L L + LG+ Sbjct: 96 KANIDQWVETDGQTFGPPSGDLVHDLL-FSSVPVDEALIKKNVDKLAKVLDIYEQKLGQT 154 Query: 150 SWFAGEKLTFVDF 162 + AG++ +F D Sbjct: 155 RFLAGDEFSFADL 167 >2GDR-A nrPDB Length = 202 Score = 71.5 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 77/211 (36%), Gaps = 17/211 (8%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L Y + L ++E + +L+V +P Sbjct: 1 MKLYYSPGACSLSP-HIALREAGLNFELVQVDLASKKTASGQDYLEVNPA-----GYVPC 54 Query: 67 LL-DGKNKITQSNAILRYIARKHNMCGETEE------EKIRVD-IIENQVMDFRTQLIRL 118 L D +T+ AI++Y+A + + G+ E+ + + + L Sbjct: 55 LQLDDGRTLTEGPAIVQYVADQ--VPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPL 112 Query: 119 CYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178 + ++ K + L +L Q + L + G++L+ D + +L + + Sbjct: 113 FNPASSDEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYLFVVLGWSAYVNID- 171 Query: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCK 209 L +P+L+AF R E + + L+++ K Sbjct: 172 LSPWPSLQAFQGRVGGREAVQSALRAEGLIK 202 >4MPF-A nrPDB Length = 266 Score = 71.1 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 21/169 (12%) Query: 44 DYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKH----NMCGETEEEKI 99 D + Q +F LP L DG +T+S+AIL Y++ K+ + + + Sbjct: 56 DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARA 115 Query: 100 RVDIIENQVMD--------------FRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMF 145 RV D + E+ + + L L+ F Sbjct: 116 RVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQAL-QWLED--KF 172 Query: 146 LGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEA 194 LG + AG+++T D + + L Q + + P L A+ R EA Sbjct: 173 LGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEA 221 >5ZWP-A nrPDB Length = 208 Score = 70.7 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 26/222 (11%), Positives = 68/222 (30%), Gaps = 30/222 (13%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M Y ++ + + +K +A ++ + ++L + + + P Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLLNL-QAGEHLKPEFLKINPQHTI-----PT 54 Query: 67 LLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRVD-IIENQVMDFRTQLIRLCYS 121 L+DG + +S AI+ Y+ K+ + + +++ ++ + + Y Sbjct: 55 LVDGDFALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYP 114 Query: 122 SDHEKL--KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 K P+ +++ + FL + AG+ LT D + + Sbjct: 115 QIFAKAPADPELFKKIETAFDFLNTFLKGHEYAAGDSLTVADLALLASVSTFEVASFD-- 172 Query: 180 DEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 +A + + + W Sbjct: 173 ------------ISKYPNVAKWYANLKTVAP---GWEENWAG 199 >3UAR-A nrPDB Length = 227 Score = 70.3 bits (171), Expect = 7e-13, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 66/203 (32%), Gaps = 12/203 (5%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L Y+ ++L +E + G + +L V K + L Sbjct: 3 MKLYYFPGACSLAP-HIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQL-- 59 Query: 67 LLDGKNKITQSNAILRYIAR---KHNMC--GETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 D +T+ IL+Y+A + + T E ++ + + Sbjct: 60 --DDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNP 117 Query: 122 SDHEKLKPQYLEELPGQLKQFSMFL-GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 E K L L +L L W G++ + D +L L Sbjct: 118 ESPEASKQIALGLLSRRLDYVEDRLEAGGPWLMGDRYSVADAYLSTVLGWCEYLKID-LS 176 Query: 181 EFPNLKAFMCRFEALEKIAAYLQ 203 ++P + A++ R +A + A ++ Sbjct: 177 KWPRILAYLERNQARPAVQAAMK 199 >2C3Q-A nrPDB Length = 247 Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 41/197 (20%), Positives = 67/197 (34%), Gaps = 25/197 (12%) Query: 17 LAHAIRLLLEFT---DTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNK 73 L+ R + F D +E + D + Q L F +P L DG Sbjct: 17 LSQPCRAVYIFAKKNDIPFELRIV------DLIKGQHLSDAFAQVNPLKKVPALKDGDFT 70 Query: 74 ITQSNAILRYIARKHNM----CGETEEEKIRVDIIEN-QVMDFRTQLIRLCY-------- 120 +T+S AIL Y+ RK+ + + + + RVD Q R +R + Sbjct: 71 LTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVF 130 Query: 121 --SSDHEKLKPQYLEELPGQLKQFS-MFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 + L EL L+ FL ++ G ++ D + L + Sbjct: 131 LGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQ 190 Query: 178 CLDEFPNLKAFMCRFEA 194 + P L + R EA Sbjct: 191 VFEGRPKLATWRQRVEA 207 >3LSZ-A nrPDB Length = 225 Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 63/206 (30%), Gaps = 19/206 (9%) Query: 15 RGLAHAIRLLLEFTDTSYEE------KRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68 R A LL D +E R P+ + ++ +P L Sbjct: 10 RSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVN-PLGQIPCLE 68 Query: 69 DGKNKITQSNAILRYIARKHN--MCGETEEEKIR-VDIIENQVMDFRTQLIRLCY----- 120 + +T+S AI +IAR + +E E V + + Sbjct: 69 EEGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSG 128 Query: 121 ---SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 S + + E L L + + G + T D + L + P Sbjct: 129 GGTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVADLNLAETLRYGQAH-PA 187 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQ 203 L+ FP + A++ R ++ ++ Sbjct: 188 LLEPFPAVAAWLDRCQSRPAFRLMME 213 >1F2E-A nrPDB Length = 201 Score = 67.3 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 59/185 (31%), Gaps = 12/185 (6%) Query: 25 LEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL-DGKNKITQSNAILRY 83 L T +E + +L V +P L D +T++ AIL Y Sbjct: 18 LRETGADFEAVKVDLAVRKTEAGEDFLTVNPS-----GKVPALTLDSGETLTENPAILLY 72 Query: 84 IARKHNMCGETEEE-----KIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQ 138 IA ++ G E + + +F + L + ++ K E + Sbjct: 73 IADQNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNH 132 Query: 139 LKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKI 198 L L +AG + D Y +L + +P L A+ + + Sbjct: 133 LAALDKELAGRDHYAGNAFSVADIYLYVMLGWPAYVGID-MAAYPALGAYAGKIAQRPAV 191 Query: 199 AAYLQ 203 A L+ Sbjct: 192 GAALK 196 >1PN9-A nrPDB Length = 209 Score = 65.7 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 31/197 (15%), Positives = 65/197 (32%), Gaps = 18/197 (9%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPN--L 64 M Y A+++ D + +K + P + Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVEL--------NLKLTDLMKGEHMKPEFLKLNPQHCI 52 Query: 65 PYLLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRVD-IIENQVMDFRTQLIRLC 119 P L+D + +S AI Y+A K+ + + +++ V+ + + + Sbjct: 53 PTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYH 112 Query: 120 YSSDHEKL--KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 Y K P+ +++ + + FL + AG LT D + + Sbjct: 113 YPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYEVAGFD 172 Query: 178 CLDEFPNLKAFMCRFEA 194 +PN+ A+ R +A Sbjct: 173 F-APYPNVAAWFARCKA 188 >2PMT-A nrPDB Length = 203 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 64/198 (32%), Gaps = 13/198 (6%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L Y ++L T + +R +L + K +P Sbjct: 1 MKLYYTPGSCSLSP-HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPK-----GQVPV 54 Query: 67 LL-DGKNKITQSNAILRYIAR---KHNMCG--ETEEEKIRVDIIENQVMDFRTQLIRLCY 120 L D + +T+ AI++Y+A N+ + E +++ + + L Sbjct: 55 LQLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFS 114 Query: 121 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD 180 S E P +L + + L K G+ T D + L Q L Sbjct: 115 SDTPESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYLF-TLSQWAPHVALDLT 173 Query: 181 EFPNLKAFMCRFEALEKI 198 + +L+ ++ R + Sbjct: 174 DLSHLQDYLARIAQRPNV 191 >1JLV-A nrPDB Length = 209 Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 74/197 (37%), Gaps = 24/197 (12%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M Y A+++ + T A ++ + ++L + + + P Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVEL-NLKLTNLMAGEHMKPEFLKINPQHCI-----PT 54 Query: 67 LLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRV------DI--IENQVMDFRTQ 114 L+D + +S AI Y+A K+ + + +++ V D+ + + D+ Sbjct: 55 LVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYP 114 Query: 115 LIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIF 174 I ++ E K ++ + + FL + AG+ LT D + + Sbjct: 115 QIFAKQPANAENEK-----KMKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYDVA 169 Query: 175 DPKCLDEFPNLKAFMCR 191 + L ++P++ A+ R Sbjct: 170 GFE-LAKYPHVAAWYER 185 >3MAK-A nrPDB Length = 209 Score = 63.8 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 23/219 (10%), Positives = 67/219 (30%), Gaps = 30/219 (13%) Query: 10 GYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLD 69 Y ++ + + +K +A ++ + ++L + + + P L+D Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLLNL-QAGEHLKPEFLKINPQHTI-----PTLVD 58 Query: 70 GKNKITQSNAILRYIARKHN----MCGETEEEKIRVD-IIENQVMDFRTQLIRLCYSSDH 124 + +S AI Y+ K+ + + +++ ++ + + Y Sbjct: 59 NGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVF 118 Query: 125 EKL--KPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEF 182 K P+ +++ + + FL + AG+ LT D + + + Sbjct: 119 AKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEVAKFE----- 173 Query: 183 PNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGN 221 + + ++ + W Sbjct: 174 ---------ISKYANVNRWYENAKKVTP---GWEENWAG 200 >5F05-A nrPDB Length = 212 Score = 62.3 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 23/153 (15%), Positives = 46/153 (30%), Gaps = 15/153 (9%) Query: 60 DFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETE------------EEKIRVDIIENQ 107 F +P +DG K+ +S AI +Y+A ++ G +++ + Sbjct: 50 PFGQVPAAVDGDLKLFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPS 109 Query: 108 VMDF--RTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDF-LT 164 + L + L L + L + + A + T D Sbjct: 110 ASKLVWEQVFKPVFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHL 169 Query: 165 YDILDQNRIFDPKCLDEFPNLKAFMCRFEALEK 197 +I K D P++ A++ Sbjct: 170 PNIQALLGTPSKKLFDSRPHVSAWVASITGRPA 202 >2IL3-A nrPDB Length = 221 Score = 61.5 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 77/208 (37%), Gaps = 26/208 (12%) Query: 1 MSCESSMVLGYWDIRGLAHAIR---LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKL 57 MS L L+ R L + E+K D+ + +++ + + Sbjct: 1 MSNLVLYTLH------LSPPCRAVELTAKALGLELEQKTINLLTG-DHLKPEFVKLNPQH 53 Query: 58 DLDFPNLPYLLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRVDI---IENQVMD 110 + P L D IT+S+AI+ Y+ K+ + + ++ RV+ E+ V+ Sbjct: 54 TI-----PVLDDNGTIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLF 108 Query: 111 FRTQLI--RLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDIL 168 R + I R+ + + + +E + + L + AG +T DF + Sbjct: 109 ARMRFIFERILFFGKSD-IPEDRVEYVQKSYELLEDTLVD-DFVAGPTMTIADFSCISTI 166 Query: 169 DQNRIFDPKCLDEFPNLKAFMCRFEALE 196 P + P + A++ R + L Sbjct: 167 SSIMGVVPLEQSKHPRIYAWIDRLKQLP 194 >2CZ2-A nrPDB Length = 223 Score = 60.3 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 57/188 (30%), Gaps = 22/188 (11%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 +R+ L YE D Q +F+ +P L I QS AI Sbjct: 27 VRIALALKGIDYEIVPINL----IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAI 82 Query: 81 LRYIARKH---NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH---------EKLK 128 + Y+ + + +++ V +I + + L L +K+ Sbjct: 83 MEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVI 142 Query: 129 PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 L L+ + + G++++ D + F L +P + Sbjct: 143 TSGFNALEKILQSTA-----GKYCVGDEVSMADVCLVPQVANAERFKVD-LSPYPTISHI 196 Query: 189 MCRFEALE 196 ALE Sbjct: 197 NKELLALE 204 >3TOT-A nrPDB Length = 226 Score = 59.9 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 64/204 (31%), Gaps = 31/204 (15%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL-DGKNKITQSNA 79 +R++L Y+ + + +P L+ D + S Sbjct: 17 VRVVLAEKKIDYQ--FVLEDVWNADTQIHQFN-------PLGKVPCLVMDDGGALFDSRV 67 Query: 80 ILRY------IARKHNMCGETEEEKIRV---DIIENQVMD----FRTQLIRLCYSSDHEK 126 I Y +AR + + E++ V + + + ++D R + + E Sbjct: 68 IAEYADTLSPVAR---LIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSES 124 Query: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP--KCLDEFPN 184 + ++ LK S L +W G LT D L P ++ N Sbjct: 125 WITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHAN 184 Query: 185 LKAFMCRFEALEKIAAYLQSDQFC 208 L AF R E +L++ Sbjct: 185 LAAFYTRIEKRPS---FLETQPQA 205 >3IBH-A nrPDB Length = 233 Score = 59.9 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 59/180 (32%), Gaps = 20/180 (11%) Query: 48 SQWLDVKFKLDLDF----PNLPYLL-DGKNKITQSNAILRYIARKHN---MCGETEEEKI 99 + W K + +P L D I + AI YI + G+T EK Sbjct: 52 NLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKG 111 Query: 100 RVDII----ENQVMD-----FRTQLIRLCYSSDHEKLKPQYLEELPGQLK---QFSMFLG 147 + ++ E +++D F L + + K L + L F L Sbjct: 112 VIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLR 171 Query: 148 KFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQF 207 + + AG+ + D L I + +E L+A+ R + + L+ Sbjct: 172 ERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRSK 231 >4IKH-A nrPDB Length = 244 Score = 59.6 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 76/199 (38%), Gaps = 19/199 (9%) Query: 24 LLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF---PNLPYLLDGKNKITQSNAI 80 +LE YE R + E D ++L V + P+ P D + +S AI Sbjct: 39 MLEEIGLPYEAHRVSF-ETQDQMTPEFLSVSPNNKIPAILDPHGPG--DQPLALFESGAI 95 Query: 81 LRYIARKHN--MCGETEEEKIRVDIIENQVMDFRTQLIRLCY-----SSDHEKLKP--QY 131 L Y+A K + E+ + + Q+ ++ + ++E +P +Y Sbjct: 96 LIYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYEDKRPLERY 155 Query: 132 LEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY----DILDQNRIFDPKCLDEFPNLKA 187 + E L LG W GE+ T D T+ +++ + +D FP +K Sbjct: 156 VNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIGFYEAGELVGIDNFPEVKR 215 Query: 188 FMCRFEALEKIAAYLQSDQ 206 + +F A + L+ + Sbjct: 216 VLAKFVARPAVIRGLEIPK 234 >2PVQ-A nrPDB Length = 201 Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 65/208 (31%), Gaps = 18/208 (8%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L Y ++L YE + D + V + +P Sbjct: 1 MKLYYKVGAASLAP-HIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPR-----GAVPA 54 Query: 67 LLDG-KNKITQSNAILRYIARKHNM------CGETEEEKIRVDIIENQVMDFRTQLIRLC 119 L ITQ+ AIL+YI ++ G E+ R+ D L Sbjct: 55 LEVKPGTVITQNAAILQYIGDHSDVAAFKPAYGS--IERARLQEALGFCSDLHAAFSGLF 112 Query: 120 YSSDHEKLKPQYLEELPGQLKQFSMFLG-KFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178 + E+ + + + +L Q L K +++ G+ T D ++ + Sbjct: 113 APNLSEEARAGVIANINRRLGQLEAMLSDKNAYWLGDDFTQPDAYA-SVIIGWGVGQKLD 171 Query: 179 LDEFPNLKAFMCRFEALEKI-AAYLQSD 205 L +P R A + A+ + Sbjct: 172 LSAYPKALKLRERVLARPNVQKAFKEEG 199 >3M3M-A nrPDB Length = 210 Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 68/199 (34%), Gaps = 21/199 (10%) Query: 11 YWDIR-GLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL- 68 Y D R G + I+L+L YE +A D F +P L Sbjct: 7 YGDYRSGNCYKIKLMLNLLGLPYE------WQAVDILGGDTQTEAFLAKNPNGKIPVLEL 60 Query: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRV---DIIENQVMDFRTQLIRLC--YSSD 123 + + +SNAIL ++A + +V E + + R Y Sbjct: 61 EDGTCLWESNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGL 120 Query: 124 HEKLKPQYLEELP---GQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK--C 178 E+ + +YL+ L L + + GE + D Y + D Sbjct: 121 PEERREEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALYA---YTHVADEGGFD 177 Query: 179 LDEFPNLKAFMCRFEALEK 197 L +P ++A+M R ++ + Sbjct: 178 LSRYPGIQAWMQRVQSHPR 196 >5F0G-A nrPDB Length = 215 Score = 58.8 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 28/179 (15%), Positives = 52/179 (29%), Gaps = 23/179 (12%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M Y G + ++ + +K E F +P Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPE------FVKLNPQHTIPT 54 Query: 67 LLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRV------DI--IENQVMDFRTQ 114 L+D I +S AI Y+ K+ + +++ + D+ + + Sbjct: 55 LVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYP 114 Query: 115 LIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 L R E LK + FL + AG++LT D + + Sbjct: 115 LFRTGKPGSDEDLK-----RIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTFEV 168 >1V2A-A nrPDB Length = 210 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Query: 64 LPYLLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRVD-IIENQVMDFRTQLIRL 118 +P L+D + + +S AI+ Y+ + + + + + V+ + + ++I + Sbjct: 51 IPTLVDNGHVVWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDV 110 Query: 119 CYS-SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 177 + E+ + +E+L G L F+ + ++ A + LT D + Sbjct: 111 IHLVMKKEQPSDEQMEKLKGALDLLEQFVTERAYAAADHLTVADICLLGTVTALNWLK-H 169 Query: 178 CLDEFPNLKAFMCRFEA-LEKIAAYLQS 204 L+ FP+++A++ R A + + + Sbjct: 170 DLEPFPHIRAWLERVRAEMPDYEEFSKQ 197 >3LFL-A nrPDB Length = 240 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 18 AHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQS 77 A RL+L+ +E P +W K F +P L + + ++ Sbjct: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKN----PFGLVPVLENSQGQLIYE 85 Query: 78 NAILR-YIARKH---NMCGETEEEKIRVDIIEN---QVMDFRTQLIRLCYSSDHEKLKPQ 130 +AI Y+ + + + EK +I +V IR D+ LK + Sbjct: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 Query: 131 YLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFD-PKCLDEFPNLKAFM 189 + +E K + K ++F G ++ +D+L + ++ +C+D P LK +M Sbjct: 146 FRKEF---TKLEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWM 202 Query: 190 CRFEALEKIAAYLQSDQ 206 + ++A L S++ Sbjct: 203 AAMKEDPTVSALLTSEK 219 >1FW1-A nrPDB Length = 216 Score = 58.4 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 31/189 (16%), Positives = 60/189 (31%), Gaps = 22/189 (11%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 +R+ L Y+ T D Q F+ +P L I QS AI Sbjct: 20 VRIALALKGIDYK----TVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAI 75 Query: 81 LRYIARKH---NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDH-EKLKPQY----- 131 + Y+ + + +++ V +I + + L L E+++ + Sbjct: 76 IEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAI 135 Query: 132 ---LEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 L L+ + + G+++T D + F L +P + + Sbjct: 136 TCGFNALEQILQSTAGI-----YCVGDEVTMADLCLVPQVANAERFKVD-LTPYPTISSI 189 Query: 189 MCRFEALEK 197 R LE Sbjct: 190 NKRLLVLEA 198 >3M8N-A nrPDB Length = 225 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 41/201 (20%), Positives = 65/201 (32%), Gaps = 17/201 (8%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 L G ++ +RL L D Y D R + F +P Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPY------RAVEVDILRGESRTPDFLAKNPSGQVPL 57 Query: 67 LLDG-KNKITQSNAILRYIARKHNMCGETEEEKIRVD--IIENQVM---DFRTQLIRLCY 120 L + +SNAIL Y+A ++ +T ++ + Q + + LC Sbjct: 58 LETAPGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCL 117 Query: 121 SSDHEKLK----PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP 176 L+ +LE L+ L +FA +LT D Y D Sbjct: 118 VKGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDF 177 Query: 177 KCLDEFPNLKAFMCRFEALEK 197 L FP + A++ R E Sbjct: 178 D-LSTFPAVNAWLRRVEQTPG 197 >3UBL-A nrPDB Length = 242 Score = 56.9 bits (136), Expect = 6e-09, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 48/164 (29%), Gaps = 18/164 (10%) Query: 29 DTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKH 88 YE+ R + D+ + +P L I +S AIL ++ Sbjct: 26 GLEYEQIRIAPSQEEDFLKIS----------PMGKIPVLEMDGKFIFESGAILEFLDTIF 75 Query: 89 ----NMCGETEEEKIR---VDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQ 141 + E E R + I +D + I L + ++ + L +K Sbjct: 76 PQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLVKGIKA 135 Query: 142 FSMFLGKFSWFAGEKLTFVDFLTYDILDQN-RIFDPKCLDEFPN 184 + + AG T D + L P + P Sbjct: 136 LQRVVRFSPYIAGNVFTLADCSGFAHLSVLDEELRPFYPNNHPL 179 >5F8B-A nrPDB Length = 244 Score = 56.9 bits (136), Expect = 7e-09, Method: Composition-based stats. Identities = 17/116 (14%), Positives = 38/116 (32%), Gaps = 16/116 (13%) Query: 62 PNLPYLL-DGKNKITQSNAILRYIA---RKHNMCGETEEEKIRV---------DIIENQV 108 +P K+ + AI YI + + G+ ++E + +I+ Sbjct: 48 GKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILMT 107 Query: 109 MDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT 164 QL + Y D + + + +L ++ G++L+ D Sbjct: 108 QQLLPQLGVIPYDRDQVEFFANMTQ---RSVDVVEEYLQDRTFLVGDQLSLADLFC 160 >1N2A-A nrPDB Length = 201 Score = 56.1 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 52/147 (35%), Gaps = 7/147 (4%) Query: 60 DFPNLPYLLDGKNKIT-QSNAILRYIARKHN----MCGETEEEKIR-VDIIENQVMDFRT 113 +P LL + + AI++Y+A + + + ++ + + Sbjct: 48 PKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHK 107 Query: 114 QLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 L E+ KP +L +L+ + L W G++ T D + +L + Sbjct: 108 GFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVL-RWAY 166 Query: 174 FDPKCLDEFPNLKAFMCRFEALEKIAA 200 L+ ++ AFM R ++ Sbjct: 167 AVKLNLEGLEHIAAFMQRMAERPEVQD 193 >4MDC-A nrPDB Length = 252 Score = 54.6 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 31/237 (13%), Positives = 71/237 (29%), Gaps = 41/237 (17%) Query: 4 ESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDL-DFP 62 +S L + + + +RL+L E + W + + L L Sbjct: 21 QSMPTLYHHPMSPASRFVRLILSEYGYQTE----------LSEEQPWENRRDFLTLNPAG 70 Query: 63 NLPYLLDGKNK-----------ITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMD- 110 LP +D + + +++ I++ R + E ++ + + + Sbjct: 71 TLPVYVDDSMRALCGATIISEYLDETSGIMK---RDRRLLAEDPFQRAEIRRLTEWFLQK 127 Query: 111 ---------FRTQLIRLCYSSDHEKLKPQYL------EELPGQLKQFSMFLGKFSWFAGE 155 R ++ +L + D P + +K S G W AG+ Sbjct: 128 MEADVTRPLVRERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGD 187 Query: 156 KLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPI 212 ++++ D + + P K + R ++ L P+ Sbjct: 188 RISYGDLAAAAAISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFRPLLAERVRGVTPV 244 >3GH6-A nrPDB Length = 210 Score = 53.8 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 24/176 (13%), Positives = 62/176 (35%), Gaps = 22/176 (12%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L Y ++ + + +++K A + ++L + + + P Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTI-----PT 55 Query: 67 LLDGKNKITQSNAILRYIARKHN----MCGETEEEKIRV------DI--IENQVMDFRTQ 114 L D + +S AI+ Y+ K+ + + +++ + D+ + ++ Sbjct: 56 LHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYP 115 Query: 115 LIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQ 170 I L ++ E K ++ + + FL ++ AG + D + Sbjct: 116 QIFLKKPANEENYK-----KIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVST 166 >3GX0-A nrPDB Length = 215 Score = 52.2 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 69/198 (34%), Gaps = 15/198 (7%) Query: 11 YWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD--FPNLPYLL 68 Y+ H I L LE + Y + G+ + R ++L + + + P Sbjct: 5 YFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQF-RPEFLRISPNNKIPAIVDHSPA-- 61 Query: 69 DGK--NKITQSNAILRYIARKHNMC--GETEEEKIRVDIIENQVMDFRTQLI-RLCYSSD 123 DG + +S AIL Y+A K + ET E + + QV L ++ Sbjct: 62 DGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHA 121 Query: 124 HEKLKPQYLEELPGQLKQFSMFLGKF----SWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 + P +E + ++ L K W GE + D + ++ L Sbjct: 122 APQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTR-QRIDL 180 Query: 180 DEFPNLKAFMCRFEALEK 197 +P +K + R + Sbjct: 181 AMYPAVKNWHERIRSRPA 198 >4G0L-A nrPDB Length = 328 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 52/154 (33%), Gaps = 18/154 (11%) Query: 64 LPYLLDGKNKIT---QSNAILRYIARKHNMCGETEEEKI------RVDIIENQVMD-FRT 113 +P L D KN +S I+R + G + ++D + + D Sbjct: 133 VPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNN 192 Query: 114 QLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDIL----- 168 + + +++ E + L + LG+ + G +LT D + L Sbjct: 193 GVYKAGFATSQEAYDEAVAKVFE-SLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDP 251 Query: 169 --DQNRIFDPKCLDEFPNLKAFMCRFEALEKIAA 200 + D + ++ NL F+ + IA Sbjct: 252 VYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAE 285 >3PR8-A nrPDB Length = 229 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 43/236 (18%), Positives = 85/236 (36%), Gaps = 33/236 (13%) Query: 5 SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 S+ L + + + ++L L ++EE + G+AP + Sbjct: 1 MSLKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEVS----------PRGKV 50 Query: 65 PYLLDGKNKITQSNAILRYIARKHN---MCGETEEEKIRVDIIENQVMDFRTQLIRLCYS 121 P L +++++ IL YI + + + +V + ++ + R CY+ Sbjct: 51 PVLETEHGFLSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYA 110 Query: 122 SDH----------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT---YDIL 168 EK + L LK+ F + AGE+LT D + D+ Sbjct: 111 ESFFGMSVEPLIKEKARADLLAGF-ATLKRNGRF---APYVAGEQLTLADLMFCFSVDLA 166 Query: 169 DQN--RIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222 + ++ + L +FP KA + + L D+ MP +M + G + Sbjct: 167 NAVGKKVLNIDFLADFPQAKALLQLMGENPHMPRILA-DKEASMPAFMEMIRSGKR 221 >4PXO-A nrPDB Length = 238 Score = 48.4 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 44/212 (20%), Positives = 73/212 (34%), Gaps = 24/212 (11%) Query: 6 SMVLGYWDIRGLAH-AIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNL 64 SMV Y + R A +R+ L +YEE +A D + +L + + + Sbjct: 22 SMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDL-DAGDQHKPDFLAINPQ-----GAV 75 Query: 65 PYLLDGKNK-ITQSNAILRYIARKHNMCGETEEE-------KIRVDIIENQVMDFRTQLI 116 P L DG +TQS AIL Y+ EE + ++ + Sbjct: 76 PALFDGDGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRV 135 Query: 117 RLCYSSDHEKLKPQYLEELPGQ----LKQFSMFL----GKFSWFAGEKLTFVDFLTYDIL 168 R ++ + + LE L LK L G + G+ ++ D + Sbjct: 136 RTFLMENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLW 195 Query: 169 DQNRIFDPKCLDEFPNLKAFMCRFEALEKIAA 200 IF +P +K AL+ +A Sbjct: 196 VGTGIFGIDT-AAYPTVKRISEEVLALDAVAR 226 >4CHS-A nrPDB Length = 219 Score = 48.0 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 35/195 (17%), Positives = 66/195 (33%), Gaps = 31/195 (15%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP---NLPYLLDGKNKITQS 77 +R+ L YE Y + L P +P L+ I++S Sbjct: 19 VRIALAEKGIEYE-----------YKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISES 67 Query: 78 NAILRYIARKHN----MCGETEEEKIRV----DIIENQVMDFRTQLIRLCYSSDHEKLKP 129 ++YI N + ++ + D ++ ++ D ++ + E K Sbjct: 68 LIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIW-TSKGEEKEAAKK 126 Query: 130 QYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT---YDILDQNRIFDPKCLDE-FPNL 185 +++E L K LG ++F G+ + FVD Y F ++ P Sbjct: 127 EFIEAL----KLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRF 182 Query: 186 KAFMCRFEALEKIAA 200 A+ R E +A Sbjct: 183 VAWAKRCLQKESVAK 197 >4FQU-A nrPDB Length = 313 Score = 47.6 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 15/138 (10%) Query: 76 QSNAILRYIARKHNMCGETEEEKI------RVDIIENQV-MDFRTQLIRLCYSSDHEKLK 128 +S+ I+R + + G + +D I +V + R +++ E + Sbjct: 137 ESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYE 196 Query: 129 PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDIL-----DQNRIFDPKC--LDE 181 + L L W G++LT D + L + F + + Sbjct: 197 EAFYPLF-DTLDWLEEHLTGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIAD 255 Query: 182 FPNLKAFMCRFEALEKIA 199 +PNL + + + E++A Sbjct: 256 YPNLSRLVGKLASHERVA 273 >1E6B-A nrPDB Length = 221 Score = 46.8 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 66/223 (29%), Gaps = 23/223 (10%) Query: 2 SCESSMVLG-YWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD 60 S E + L YW AH +R+ L YE + + D FK Sbjct: 4 SGEEKLKLYSYWRS-SCAHRVRIALALKGLDYE------YIPVNLLKGDQFDSDFKKINP 56 Query: 61 FPNLPYLLDGKNKITQSNAILRYIARKH---NMCGETEEEKI---RVDIIENQVMDFRTQ 114 +P L+DG I S AI+ Y+ K+ + ++ + I + Sbjct: 57 MGTVPALVDGDVVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQN 116 Query: 115 LIRLCYSSD----HEKLK---PQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDI 167 L + Y + EK + K GK + G+++ D Sbjct: 117 LAVIRYIEEKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHA--TGDEIYLADLFLAPQ 174 Query: 168 LDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKM 210 + ++ +P L + L L Q Sbjct: 175 IHGAINRFQINMEPYPTLAKCYESYNELPAFQNALPEKQPDAP 217 >4J2F-A nrPDB Length = 223 Score = 46.5 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 54/157 (34%), Gaps = 12/157 (7%) Query: 63 NLPYLLDGKNKITQSNAILRYIARKHN---MCGETEEEKIRVDIIENQVMDFRTQLIRLC 119 +P L+ G I +S IL Y+ + E+ + D T + + Sbjct: 53 KIPVLVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIF 112 Query: 120 YSSDHEKLKPQY--LEELPGQLKQFSMFLGKFSWFAGEKLTFVDF------LTYDILDQN 171 + E K LE L +++ +M + +F G+K+ VD ++++ Sbjct: 113 RTKGEELEKAVKNCLEVL-KTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEV 171 Query: 172 RIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFC 208 +FP L A+ F+ I L Sbjct: 172 AGVKVLESQKFPRLHAWTENFKEAPIIKENLPDRDQM 208 >5NR1-A nrPDB Length = 228 Score = 46.5 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 62/208 (29%), Gaps = 28/208 (13%) Query: 8 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 67 L ++ + + +RL L + E + E P S P L Sbjct: 6 TLHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMP---------PVL 56 Query: 68 LDGKNK----ITQSNAILRYIARKHN---MCGETEEEKIRVDIIENQVM-DFRTQLIRLC 119 ++ K++ I ++ AIL +I + G E+ + F ++ Sbjct: 57 VETKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFL 116 Query: 120 YSSDHEKLKPQY-----------LEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDIL 168 EK + E L L L W AG +++ DF L Sbjct: 117 LHEKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHL 176 Query: 169 DQNRIFDPKCLDEFPNLKAFMCRFEALE 196 F +F K + + ++ Sbjct: 177 SVIDYFGDVPWKDFQAAKTWYMKLKSRP 204 >5J5N-A nrPDB Length = 231 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 33/200 (16%), Positives = 70/200 (35%), Gaps = 25/200 (12%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 +RL L YE Y+ + + + +++ +P L+ + +S I Sbjct: 31 VRLALAEKGVKYE---YSEEDLWNK-----SALLLQMNPVNKQIPVLVHNGKPVCESLII 82 Query: 81 LRYIARKHN----MCGETEEEKIR----VDIIENQVMDFRTQLIRLCYSSDHEKLKPQYL 132 ++YI + ++ + D ++ ++ D ++ + E K ++ Sbjct: 83 VQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIW-TKKGEEQEAAKKDFI 141 Query: 133 EELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILD----QNRIFDPKCLDEFPNLKAF 188 + L K LG +F GE + +VD I + E P + A+ Sbjct: 142 DSL----KLMEGELGDKPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAY 197 Query: 189 MCRFEALEKIAAYLQSDQFC 208 R E ++ L+ Q Sbjct: 198 CKRCLQKETVSKALEDPQKV 217 >4QQ7-A nrPDB Length = 207 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 28/201 (13%), Positives = 64/201 (31%), Gaps = 21/201 (10%) Query: 19 HAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSN 78 RL+L +E + P+ + +P L++ + +SN Sbjct: 18 QRCRLVLFEKGMDFEIRDVDLFNKPEDISVMN---------PYGQVPILVERDLILYESN 68 Query: 79 AILRYIARKH---NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLE-- 133 I YI + + ++ R + +++F +L + ++EK K Sbjct: 69 IINEYIDERFPHPQLMPADPVQRARARLF---LLNFEKELFVHVSTLENEKGKAAEKNHE 125 Query: 134 ----ELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFM 189 + +L Q + K + GE+ + +D +L + + + L + Sbjct: 126 KARLAIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAAPLMKYA 185 Query: 190 CRFEALEKIAAYLQSDQFCKM 210 R + L + Sbjct: 186 ERIFSRPAYIEALTPSEKVMR 206 >4IGJ-A nrPDB Length = 242 Score = 45.7 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 65/212 (30%), Gaps = 35/212 (16%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL---DGKNKI-TQ 76 +RL L +YE A D + + +P L DG+ + Q Sbjct: 39 VRLGLALKGLAYE------YRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQ 92 Query: 77 SNAILRYIARKH---NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLE 133 S AIL ++ +H + + RV + V + + E Sbjct: 93 SMAILEWLEERHPEPALLPPDLWGRARVRALAEHVN-------SGTQPMQNALVLRMLRE 145 Query: 134 ELPGQLKQFSMFL--------------GKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCL 179 ++PG ++++ F G + G+ T D L R F L Sbjct: 146 KVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD-L 204 Query: 180 DEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211 + +P L+ AL A Q P Sbjct: 205 EPYPTLRRVDEACAALAPFQAAHPDRQPDAPP 236 >4BVY-B nrPDB Length = 186 Score = 44.9 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 56/159 (35%), Gaps = 19/159 (11%) Query: 63 NLPYLL-DGKNKITQSNAILRYIARKHN---MCGETEEEKIRVDIIENQVMDFRTQLIRL 118 +P L + +T I ++ ++ N + G T EEK I Q +++R + Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKA----IVQQWLEYRVTQVDG 96 Query: 119 CYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT-YDILDQNRIFDPK 177 S + ++ LK + +L + G T D L Y + + Sbjct: 97 HSSKN----------DIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQ 146 Query: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKM 216 +++ N+ + + I +L S F K + Sbjct: 147 EKEKYLNVSRWFSHIQHYPGIRQHLSSVVFIKNRLYTNS 185 >3PPU-A nrPDB Length = 352 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 61/174 (35%), Gaps = 26/174 (14%) Query: 47 RSQWLDVKFKLDLDFPNLPYLLD---GKNKITQSNAILRYIARKHN-MCGETEEEKIRVD 102 + +L VK D F +P L D G +S+ I+R N + E+K ++D Sbjct: 142 KDLYLKVKPDYDGRF-TVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLL---PEDKAKLD 197 Query: 103 II-------ENQVMD-FRTQLIRLCYSSDHEKLKPQYLEE---LPGQLKQFSMFLGKFSW 151 + ++V D + Y S + Y L L + L + Sbjct: 198 LYPESLRAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEKMLEGQDY 257 Query: 152 FAGEKLTFVDFLTYDILDQNRIFDPKCLDEFP-NLKAFMCRFEALEKIAAYLQS 204 G +LT D + + + FDP + F NL+ + +++ Sbjct: 258 LIGGQLTEADIRLFVTIVR---FDPVYVTHFKCNLRTIRD---GYPNLHRWMRK 305 >2VO4-A nrPDB Length = 219 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 61/191 (31%), Gaps = 23/191 (12%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP---NLPYLLDGKNKITQS 77 +R+ L YE Y + L P +P L+ I +S Sbjct: 19 VRIALAEKGIKYE-----------YKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICES 67 Query: 78 NAILRYIARKHN----MCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLE 133 ++YI N + ++ + + V L R ++S E+ K + Sbjct: 68 LIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEE-KEAAKK 126 Query: 134 ELPGQLKQFSMFLGKFSWFAGEKLTFVDFLT---YDILDQNRIF-DPKCLDEFPNLKAFM 189 E LK LG ++F G+ L FVD Y F E P A+ Sbjct: 127 EFIEALKLLEEQLGDKTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAWA 186 Query: 190 CRFEALEKIAA 200 R E +A Sbjct: 187 KRCLQKESVAK 197 >4USS-A nrPDB Length = 325 Score = 44.2 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 27/156 (17%), Positives = 54/156 (34%), Gaps = 23/156 (14%) Query: 64 LPYLLDGKNKIT---QSNAILRYIARKHNMCGET-------EEEKIRVDIIENQVMDFRT 113 +P L D K K +S+ I+R + N E + ++D V D Sbjct: 129 VPVLWDKKLKTIVNNESSEIIRMFNTEFNDIAENAALDLYPSHLQAQIDETNGWVYD--- 185 Query: 114 QLIRLCYSSDHEKLKPQYLEE---LPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY----- 165 + Y + + Y E L L + LG+ + G L+ D + Sbjct: 186 GINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILGRQRYICGNTLSEADIKLFVTLIR 245 Query: 166 --DILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIA 199 ++ + + K L ++PN+ + + ++ Sbjct: 246 FDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMS 281 >2JL4-A nrPDB Length = 213 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 65/196 (33%), Gaps = 22/196 (11%) Query: 7 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66 M L + G +H +R+ L YE A + + L FK +P Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYE------YLAVHLGKEEHLKDAFKALNPQQLVPA 55 Query: 67 LLDGKNKITQSNAILRYIARKH---NMCGETEEEKIRVDIIENQVM-DFRT-------QL 115 L G + QS AI+ ++ ++ + + + RV + V D + Sbjct: 56 LDTGAQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEY 115 Query: 116 IRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFS----WFAGEKLTFVDFLTYDILDQN 171 +R + +D + + + L + G+ T D ++ Sbjct: 116 LRKTFGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESA 175 Query: 172 RIFDPKCLDEFPNLKA 187 R F L +P ++A Sbjct: 176 RRFQVD-LTPYPLIRA 190 >6GCB-A nrPDB Length = 325 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 41/221 (18%), Positives = 71/221 (32%), Gaps = 41/221 (18%) Query: 13 DIRGLAHAIRL-----LLEFTDTSYEEKRYTCGEAPD------YDRSQWLDVKFKLDLDF 61 I+GL + + L + + G D Y R +L K + F Sbjct: 67 KIKGLEEIVGVTIVSPLFSAHGWPFGDVSPFPGAEADPFYNAQYVRDLYLRADPKYEGRF 126 Query: 62 PNLPYLLDGKNKIT---QSNAILRYIARKHN-----------MCGETEEEKIRVDIIENQ 107 +P L D K + +S+ I+R N + E + + +D I Sbjct: 127 -TVPVLWDKKTETVVNNESSEIIRIFNTAFNEFLPADKAAIHLYPEALKSE--IDEINEW 183 Query: 108 VMDFRTQLIRLCYSSDHEKLKPQYLEE---LPGQLKQFSMFLGKFSWFAGEKLTFVDFLT 164 V D + Y + + Y L L + L + G++LT D Sbjct: 184 VYD---TVNNGVYKAGFATTQQAYEAAVIPLFESLDRLEKILTGKDYLVGDQLTEADVRL 240 Query: 165 YDILDQNRIFDPKCLDEFP-NLKAFMCRFEALEKIAAYLQS 204 + + + FDP + F NL+ I +L+ Sbjct: 241 FVTIIR---FDPAYVGHFKCNLRTIRD---GYPAIHLWLRK 275 >4MK3-A nrPDB Length = 226 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 35/203 (17%), Positives = 60/203 (29%), Gaps = 22/203 (10%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 65 SM L A +R++L YE + +P Sbjct: 22 SMKLYASQTSPYARKVRVVLAEKKIDYE--MIEENVWSPDTTIGRFN-------PLGKVP 72 Query: 66 YLL-DGKNKITQSNAILRY---IARKHNMCGETEEEKIRV-------DIIENQVMDFRTQ 114 L+ + + S I Y ++ + + E++ V D + + + R + Sbjct: 73 CLVMEDGGAVFDSRVIAEYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLE 132 Query: 115 LIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIF 174 + + S E + ++ L S L +W G T D L Sbjct: 133 VTQRKESERSESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLDFR 192 Query: 175 DPKCL--DEFPNLKAFMCRFEAL 195 P D PNL AF + E Sbjct: 193 FPDIAWRDRHPNLVAFQEKIEKR 215 >6GZF-A nrPDB Length = 341 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 49/137 (35%), Gaps = 16/137 (11%) Query: 44 DYDRSQWLDVKFKLDLDFPNLPYLLD---GKNKITQSNAILRYIARKHN--------MCG 92 DY R ++ + +P L D +S I+R + + + Sbjct: 115 DYLRELYVRAAPDVTCRV-TVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYP 173 Query: 93 ETEEEKIRVDIIENQV-MDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSW 151 E +EK VD I + + + R ++++ E E G L + L + Sbjct: 174 EGYQEK--VDQIIDNIYEPINNGVYRAGFATEQEPYDEAVAELF-GALAHWDDVLADQRY 230 Query: 152 FAGEKLTFVDFLTYDIL 168 AG++LT D + L Sbjct: 231 LAGDRLTEADIAMFTTL 247 >6GC9-A nrPDB Length = 327 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 37/111 (33%), Gaps = 13/111 (11%) Query: 98 KIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEE---LPGQLKQFSMFLGKFSWFAG 154 + +D I V D + Y S + Y L L + L + G Sbjct: 175 RGEIDGINEWVYD---TVNNGVYKSGFATSQKAYEAAVVPLFESLDRLEKILTGKDYLVG 231 Query: 155 EKLTFVDFLTYDILDQNRIFDPKCLDEFP-NLKAFMCRFEALEKIAAYLQS 204 ++LT D + + + FDP + F N++ I +++ Sbjct: 232 DQLTEADIRLFVTIVR---FDPVYVGHFKCNIRTIRD---GYPAIDLWMRK 276 >4PTS-A nrPDB Length = 348 Score = 41.1 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 36/105 (34%), Gaps = 8/105 (7%) Query: 98 KIRVDIIENQV-MDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEK 156 + +D + + + + R ++ + Y +L + S L + + G+ Sbjct: 168 RAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLF-TKLDELSERLAQQRYLVGDT 226 Query: 157 LTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAY 201 +T D + L + FD F K + + + AY Sbjct: 227 ITEADVRLFTTLAR---FDAVYHGHF---KCNRSKLSEMPVLWAY 265 >3C8E-A nrPDB Length = 288 Score = 40.7 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 63/195 (32%), Gaps = 23/195 (11%) Query: 23 LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKN----KITQSN 78 L L T Y+ G+ D S +++V +P L D + ++ +S Sbjct: 66 LALGVTGAEYDAWLIRIGDG-DQFSSGFVEVNPNS-----KIPALRDHTHNPPIRVFESG 119 Query: 79 AILRYIARKHN-MCGETEEEKIRVD----IIENQVMDFRTQLIRL-CYSS-DHEKLKPQY 131 +IL Y+A K + ++ ++ Y+ E ++ Sbjct: 120 SILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRF 179 Query: 132 LEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY----DILDQNRIFDPKCLDE--FPNL 185 E L L + + AG++ T D + +++ + LD + ++ Sbjct: 180 TMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHV 239 Query: 186 KAFMCRFEALEKIAA 200 + + + Sbjct: 240 QRWAKEVGERPAVKR 254 >5LOL-A nrPDB Length = 215 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 34/158 (21%), Positives = 53/158 (33%), Gaps = 25/158 (15%) Query: 22 RLLLEFTDTS--YEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNA 79 R+LL + Y+ + P QW F +P + + S+ Sbjct: 27 RVLLTLEEKKLPYKTHLINVSDKP-----QW----FLDISPEGKVPVVKLDGKWVADSDV 77 Query: 80 ILRYIARKH---NMCGETEEEKIRV-DIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEEL 135 I+ + K+ ++ +T E V I + F L + EK LE L Sbjct: 78 IVGLLEEKYPEPSL--KTPPEFASVGSKIFGAFVTF---LKSKDANDGSEKALVDELEAL 132 Query: 136 PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 LK S + AGEK+T VD L + Sbjct: 133 ENHLKTHS-----GPFVAGEKITAVDLSLAPKLYHLEV 165 >3RBT-A nrPDB Length = 246 Score = 39.1 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 76/209 (36%), Gaps = 29/209 (13%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 + + L + D+ H + L+LE YE R P++ R++ +K Sbjct: 22 ALTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLK------- 74 Query: 62 PNLPYLLD----GKNKITQSNAILRYIARK---HNMCGETEEEKIRVDIIENQVMDFRTQ 114 +P L G + +S I Y+ K H + K + ++ + + + Sbjct: 75 --IPVLEIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNEL-IK 131 Query: 115 LIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFS--WFAGEKLTFVDFLTYDILDQNR 172 C+ ++ Q ++ L F L +F G + +D++ + +++ Sbjct: 132 GSLECFDTNFAFGSEQIIQTLE----IFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLY 187 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAAY 201 + C+++ + F+ + A + Sbjct: 188 LLR--CVND----RKFVEKKSLFPNFADW 210 >5ELG-A nrPDB Length = 221 Score = 37.6 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 66/200 (33%), Gaps = 25/200 (12%) Query: 23 LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILR 82 L LE +Y+ + P QW F +P L +T S+ I+ Sbjct: 28 LTLEEKSLTYKIHLINLSDKP-----QW----FLDISPQGKVPVLKIDDKWVTDSDVIVG 78 Query: 83 YIARKH-NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQ 141 + K+ + +T E V + S+H L LE L LK Sbjct: 79 ILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVE--LEALENHLKS 136 Query: 142 FSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC-----LDEFPNLKAFMCRFEALE 196 + AGE+++ VD L ++ + FP++ +M +L Sbjct: 137 HD-----GPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL- 190 Query: 197 KIAAYLQSDQFCKMPINNKM 216 ++ ++ K I+ Sbjct: 191 --DSFEKTKTEEKYVISGWA 208 >3M1G-A nrPDB Length = 362 Score = 37.6 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 30/96 (31%), Gaps = 7/96 (7%) Query: 108 VMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDI 167 + + R ++ E Y + L L L + G+ +T D Y Sbjct: 193 FTEVNNGVYRTGFAGSQEAHNEAY-KRLWVALDWLEDRLSTRRYLMGDHITEADIRLYPT 251 Query: 168 LDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQ 203 L + FD F K + + + YL+ Sbjct: 252 LVR---FDAVYHGHF---KCGRNKITEMPNLWGYLR 281 >5G5A-A nrPDB Length = 221 Score = 37.2 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 67/189 (35%), Gaps = 20/189 (10%) Query: 33 EEKRYTCGEAPDYDRSQWLDVKFKLDLD--FPNLPYLLDGKNKITQSNAILRYI----AR 86 EEK ++ W L+++ +P L+ N + +S + YI Sbjct: 24 EEKNVKFD---YREQDLWNKSPILLEMNPVHKKIPVLIHNGNPVCESLIQIEYIDEVWPS 80 Query: 87 KHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYS---SDHEKLKPQYLEELPGQLKQFS 143 K + ++ + + + RL + +HE K +++E L K Sbjct: 81 KTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEHEAGKKEFIEIL----KTLE 136 Query: 144 MFLGKFSWFAGEKLTFVDFLT---YDILDQNRIFDPKCLD-EFPNLKAFMCRFEALEKIA 199 LG ++F GE +VD Y + F ++ E P L A+ R E +A Sbjct: 137 SELGDKTYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAECPKLIAWGKRCVERESVA 196 Query: 200 AYLQSDQFC 208 L + Sbjct: 197 KSLPDSEKI 205 >3IR4-A nrPDB Length = 218 Score = 36.8 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 29/182 (15%), Positives = 53/182 (29%), Gaps = 30/182 (16%) Query: 22 RLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL-DGKNKITQSNAI 80 R++ + E + R + +P L D + +S I Sbjct: 19 RMIFGLKNIPVELNVLQNDDEATPTRMIGQKM----------VPILQKDDSRYLPESMDI 68 Query: 81 LRYIARKHNMCGE---------TEEEKIR-VDIIENQVMDFRTQLIRLCYSSDHEKLKPQ 130 + Y+ N+ G+ EE +R V+ NQ+ + + + Q Sbjct: 69 VHYVD---NLDGKPLLTGKRNPAIEEWLRKVNGYVNQL--LLPRFAKSAFDEFSTPAARQ 123 Query: 131 YL-EELPGQLKQFSMFLGKFSWFA---GEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186 Y + F L + G+ L +D L N + FP L+ Sbjct: 124 YFIRKKEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFPLLR 183 Query: 187 AF 188 Sbjct: 184 NL 185 >6EP7-A nrPDB Length = 220 Score = 36.1 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 66/208 (31%), Gaps = 24/208 (11%) Query: 4 ESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP- 62 E ++L YW R+ LE YE Y + L P Sbjct: 3 EEIILLDYWASM-YGMRTRIALEEKKVKYE-----------YREEDLSNKSPLLLQMNPI 50 Query: 63 --NLPYLLDGKNKITQSNAILRYI----ARKHNMCGETEEEKIRVDIIENQVMDFRTQLI 116 +P L+ I +S ++YI + + ++ + + + Sbjct: 51 HKKIPVLIHEGKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPC 110 Query: 117 RLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDIL----DQNR 172 + +S EK + +E + LK LG +F G + VD Sbjct: 111 KALWSESGEKQEAAKIEFIE-VLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEE 169 Query: 173 IFDPKCLDEFPNLKAFMCRFEALEKIAA 200 + + + EFP L A+ R E +A Sbjct: 170 VANLSIVLEFPKLMAWAQRCLKRESVAK 197 >5ECL-B nrPDB Length = 223 Score = 34.9 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 33/214 (15%), Positives = 65/214 (30%), Gaps = 24/214 (11%) Query: 6 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFP--- 62 ++L YW A R+ L +E Y + + L P Sbjct: 11 PILLDYWPSMFGMRA-RVALREKGVEFE-----------YREEDFSNKSPLLLQSNPIHK 58 Query: 63 NLPYLLDGKNKITQSNAILRYI----ARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRL 118 +P L+ + +S +++Y+ K+ + + + V T Sbjct: 59 KIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFK 118 Query: 119 CYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP-- 176 + E+ + E + K LG +F G+ +VD + ++ Sbjct: 119 VWGKKGEEQEAGKKEFIEAV-KILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFG 177 Query: 177 --KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFC 208 E P L A+ R E ++ L + Sbjct: 178 NFSIESESPKLIAWAKRCMEKESVSKSLPDSEKI 211 >5E32-A nrPDB Length = 333 Score = 34.1 bits (77), Expect = 0.048, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 32/103 (31%), Gaps = 8/103 (7%) Query: 105 ENQVMDFRTQLIRLCYSSDH-EKLKPQYLEELPGQLKQFSMFLGKFSWFAGE-------K 156 QV + I + ++ D EK L L G W G Sbjct: 17 TEQVDTIMEKNITVTHAQDILEKTHNGKLCNLNGVKPLILKDCSVAGWLLGNPMCDEFLN 76 Query: 157 LTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIA 199 ++ ++ N + P +++ LK + R EKI Sbjct: 77 VSEWSYIVEKASPANGLCYPGDFNDYEELKHLLSRINHFEKIK 119 >3NIV-A nrPDB Length = 222 Score = 33.8 bits (76), Expect = 0.059, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 44/149 (29%), Gaps = 16/149 (10%) Query: 64 LPYLLDGKNKITQSNAILRYIARKH---NMCGETE-EEKIRVDIIENQVMDFRTQ----- 114 +P L ++QS AI+ Y+ H + + + + D Sbjct: 56 VPSLDINGQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRV 115 Query: 115 LIRLC--YSSDHEKLKPQYLEELPGQLKQFSMFLG----KFSWFAGEKLTFVDFLTYDIL 168 L RL ++++ E++ Y L F LG G ++ D + Sbjct: 116 LNRLKEQFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQV 175 Query: 169 DQNRIFDPKCLDEFPNLKAFMCRFEALEK 197 F + +P + L Sbjct: 176 YNAHRFHFD-MASYPIINEINEYCLTLPA 203 >1GWC-A nrPDB Length = 230 Score = 33.8 bits (76), Expect = 0.066, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 65/200 (32%), Gaps = 33/200 (16%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 ++L L SYE+ + D + ++ K + +P L+ + +S I Sbjct: 21 VKLALALKGLSYEDV--------EEDLYKKSELLLKSNPVHKKIPVLIHNGAPVCESMII 72 Query: 81 LRYIARKH-----NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLE-- 133 L+YI ++ E+ V D R E+ K + + Sbjct: 73 LQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQA 132 Query: 134 ---------ELPGQLKQFSMFLGKFSWFA----GEKLTFVDFLTYDILDQNRIFDPKCLD 180 L K F G G L++ + L ++IFD Sbjct: 133 FAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSW--MKVTEALSGDKIFDA---A 187 Query: 181 EFPNLKAFMCRFEALEKIAA 200 + P L A++ RF L+ A Sbjct: 188 KTPLLAAWVERFIELDAAKA 207 >3BBY-A nrPDB Length = 215 Score = 32.6 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 14/26 (53%) Query: 63 NLPYLLDGKNKITQSNAILRYIARKH 88 +P L ++++S+AI Y+ + Sbjct: 59 RVPLLQIDDFELSESSAIAEYLEDRF 84 >2JZR-A nrPDB Length = 144 Score = 31.8 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 21/54 (38%), Gaps = 7/54 (12%) Query: 41 EAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGET 94 E D D +W L++P LP + D I QS I Y + G+ Sbjct: 71 EKKDGDFQKWYA-----GLNYPKLPVVTDNGGTIAQSLNISVY--PSWALIGKD 117 >5N9U-A nrPDB Length = 218 Score = 31.8 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 34/184 (18%), Positives = 56/184 (30%), Gaps = 33/184 (17%) Query: 2 SCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDF 61 + + +LG + L LE Y+ G+ P QW F Sbjct: 10 AVGAPNILGDCPF---CQRVLLSLEEKKIPYKSHLINLGDKP-----QW----FLEISPE 57 Query: 62 PNLPYLLDGKNKITQSNAILRYIARKHN---MCGETEEEKIRVDIIENQVMDFRTQLIRL 118 +P + + S+ I+ + K+ + T E V ++ Sbjct: 58 GKVPVVKIDDKWVADSDVIVGILEEKNPEPPLA--TPPEFASV------GSKIFPSFVKF 109 Query: 119 CYSSD----HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIF 174 S D E+ + L+ L G LK + AGEK+T VD L + Sbjct: 110 LKSKDPNDGTEQALLEELKALDGHLKVHG------PFIAGEKITAVDLSLAPKLYHLEVA 163 Query: 175 DPKC 178 Sbjct: 164 LGHF 167 >4J15-A nrPDB Length = 521 Score = 31.4 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 43/123 (34%), Gaps = 31/123 (25%) Query: 89 NMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGK 148 + G +EK D ++D +R Y+ + P Q + MF+ Sbjct: 394 KLLGHLVKEKYDTDFY---ILDKYPLAVRPFYTMPDPRN--------PKQSNSYDMFMRG 442 Query: 149 FSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFC 208 +G + RI DP+ L E +A LEKI AY+ S +F Sbjct: 443 EEILSGAQ---------------RIHDPQLLTE----RALHHGI-DLEKIKAYIDSFRFG 482 Query: 209 KMP 211 P Sbjct: 483 APP 485 >6AIY-A nrPDB Length = 378 Score = 30.7 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 110 DFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTF 159 D R Y E+++ + L L+ + G W AG +T+ Sbjct: 77 DLRDGY-PDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 125 >2PAR-A nrPDB Length = 201 Score = 30.7 bits (68), Expect = 0.53, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 20/54 (37%) Query: 100 RVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFA 153 VD++ ++ D LI SD EK + + L LK + F Sbjct: 106 LVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFL 159 >1G6W-A nrPDB Length = 261 Score = 30.7 bits (68), Expect = 0.54, Method: Composition-based stats. Identities = 26/190 (13%), Positives = 51/190 (26%), Gaps = 49/190 (25%) Query: 60 DFPNLPYLLD---GKNKITQSNAILRYIARKHN-------MCGETEEEKIRVD-IIENQV 108 +P L+D I +S AIL ++ K+ + + ++ +++ + Q Sbjct: 68 PNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQT 127 Query: 109 MDFRTQLIRLCYSSDHEKLK-----PQYLEELPGQLKQFSMFLGKFS------------- 150 + + + K +Y +E+ M L + Sbjct: 128 SGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAA 187 Query: 151 -------------------WFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCR 191 W G+KLT D + EFP + + Sbjct: 188 AYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKH 247 Query: 192 FEALEK-IAA 200 I A Sbjct: 248 MMRRPAVIKA 257 >5LKB-A nrPDB Length = 378 Score = 30.7 bits (68), Expect = 0.55, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 14/88 (15%) Query: 97 EKIRVDIIENQVMDFRTQLIRL--CYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAG 154 EK V E++V + L ++ S + KLK +Y E + K F + G Sbjct: 230 EKAEV--YESEVNNVFEHLDKVEKILSDKYSKLKAKYGE--EDRQKILGEF-----FTVG 280 Query: 155 EKLTFVDFLTYDILDQNRIFDPKCLDEF 182 ++LT D Y FDP + F Sbjct: 281 DQLTEADIRLY---TTVIRFDPVYVQHF 305 >3FQJ-A nrPDB Length = 417 Score = 30.7 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 110 DFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTF 159 D R Y E+++ + L L+ + G W AG +T+ Sbjct: 103 DLRDGY-PDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 151 >2IWR-A nrPDB Length = 178 Score = 30.3 bits (67), Expect = 0.61, Method: Composition-based stats. Identities = 7/38 (18%), Positives = 21/38 (55%) Query: 70 GKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQ 107 G + +S+ I R++ + + +TE E+ + +++ + Sbjct: 14 GDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDG 51 >2YV7-A nrPDB Length = 260 Score = 30.3 bits (67), Expect = 0.64, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 43/122 (35%), Gaps = 18/122 (14%) Query: 65 PYLLDGKNKITQSNAILRYIARK----HNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY 120 P L+D I ++ I R+I + +N+ + +E ++ + +L + Sbjct: 85 PILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIE-------NLYVKLKLMLV 137 Query: 121 SSDHEKLKPQYLEELPGQLKQFSMFLGKFS--WFAGEKLTFVDFLTYDILDQNRIFDPKC 178 D K L L++ + L + + G+ + D L R+ Sbjct: 138 KKDEAKN-----NALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYF 192 Query: 179 LD 180 +D Sbjct: 193 VD 194 >6JWK-A nrPDB Length = 222 Score = 30.3 bits (67), Expect = 0.65, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 22/65 (33%), Gaps = 7/65 (10%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLD-GKNKITQSNA 79 +R+ L Y+ + + LP L+D + +QS A Sbjct: 15 VRIALALKGLDYQVVPVNLRQGEQLRPADRQRN------PMGALPTLVDADGRRFSQSLA 68 Query: 80 ILRYI 84 I+ Y+ Sbjct: 69 IIDYL 73 >4KH5-A nrPDB Length = 612 Score = 30.3 bits (67), Expect = 0.70, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 20/59 (33%), Gaps = 6/59 (10%) Query: 29 DTSYEEKRYTCGEAPD-YDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQ-----SNAIL 81 + R E D Y W L F +P + +G K+ Q + AIL Sbjct: 82 GKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAIL 140 >4BWG-A nrPDB Length = 347 Score = 29.9 bits (66), Expect = 0.88, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 39/128 (30%), Gaps = 12/128 (9%) Query: 10 GYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLD 69 Y+D GL + L +T G A S KF D P Sbjct: 25 WYFDAIGLTETT-MSLTDKNTPVVVSVVDSGVAFIGGLSDSEFAKFSFTQDGSPFPVKKS 83 Query: 70 GKNKITQSNAILRYIARKHNMCGETEEEKIRVD---IIENQVMD-----FRTQLIRLCYS 121 I + A+ IA ++ + G + +I + V D + + + + Sbjct: 84 EALYIHGT-AMASLIASRYGIYGVYPH--ALISSRRVIPDGVQDSWIRAIESIMSNVFLA 140 Query: 122 SDHEKLKP 129 EK+ Sbjct: 141 PGEEKIIN 148 >5KOD-A nrPDB Length = 612 Score = 29.9 bits (66), Expect = 0.96, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 78 NAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRL 118 NA + Y+ R+H++ G T+ E + + D ++ R+ Sbjct: 50 NADVEYL-RRHDLNGRTDRETFKNIMPVITYEDIEPEINRI 89 >5HSX-A nrPDB Length = 323 Score = 29.5 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 +R + ++ + R T AP D + ++P DG TQS AI Sbjct: 254 VRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDG----TQSVAI 309 >5KEU-A nrPDB Length = 323 Score = 29.1 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 21 IRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAI 80 +R E ++ + R T AP D + ++P DG+ QS AI Sbjct: 254 VRFKWEAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGR----QSVAI 309 >4K0G-A nrPDB Length = 251 Score = 28.7 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 22/139 (15%), Positives = 38/139 (27%), Gaps = 32/139 (23%) Query: 59 LDFPNLPYLLDGKNKITQSNAILRYIA------RKHNMCGETEEEKIRVDIIENQVMDFR 112 LP+LL G T +N I ++ R + E +D Sbjct: 69 CPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNT-------AGLDIF 121 Query: 113 TQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFL------------------GKFSWFAG 154 + +S+ L + L LK +L + + G Sbjct: 122 AKFSAYIKNSN-PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDG 180 Query: 155 EKLTFVDFLTYDILDQNRI 173 +LT D L ++ Sbjct: 181 NELTLADCNLLPKLHIVQV 199 >4JUK-A nrPDB Length = 329 Score = 28.7 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 30/102 (29%), Gaps = 8/102 (7%) Query: 105 ENQVMDFRTQLIRLCYSSDH-EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 QV + + + ++ D EK L +L G W G + Sbjct: 19 TEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIN 78 Query: 164 TYDILDQNRIFDP-------KCLDEFPNLKAFMCRFEALEKI 198 + +P +++ LK + R EKI Sbjct: 79 VPEWSYIVEKANPANDLCYPGNFNDYEELKHLLSRINHFEKI 120 >4CZI-A nrPDB Length = 348 Score = 28.4 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 3/38 (7%) Query: 67 LLDGKNKITQSNAILRYIARKHNMC-GETEEEKIRVDI 103 + G +K+ + AI+ Y+ R HN+ GET E+I+ +I Sbjct: 177 VRVGGDKMDE--AIISYMRRHHNLLIGETTAERIKKEI 212 >2H30-A nrPDB Length = 164 Score = 28.0 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 21/54 (38%), Gaps = 7/54 (12%) Query: 41 EAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGET 94 E D + +W L++P LP + D I Q+ I Y + G+ Sbjct: 85 EKKDGEFQKWYA-----GLNYPKLPVVTDNGGTIAQNLNISVY--PSWALIGKD 131 >6A0Z-A nrPDB Length = 551 Score = 28.0 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 30/102 (29%), Gaps = 8/102 (7%) Query: 105 ENQVMDFRTQLIRLCYSSDH-EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 QV + + + ++ D EK L +L G W G + Sbjct: 14 TEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFIN 73 Query: 164 TYDILDQNRIFDP-------KCLDEFPNLKAFMCRFEALEKI 198 + +P +++ LK + R EKI Sbjct: 74 VPEWSYIVEKANPVNDLCYPGDFNDYEELKHLLSRINHFEKI 115 >3ADR-A nrPDB Length = 261 Score = 27.6 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 20/61 (32%), Gaps = 3/61 (4%) Query: 153 AGEKLTFVDFLTYDILDQNRI--FDPKCLDEFP-NLKAFMCRFEALEKIAAYLQSDQFCK 209 AG + DF D LD + + P L+ + + YL S+ K Sbjct: 36 AGVSNSIADFSFLDKLDYIVLTHLHIDHIGLLPELLQVYKAKVLVKSGFKKYLTSEDGLK 95 Query: 210 M 210 Sbjct: 96 K 96 >4BGZ-A nrPDB Length = 327 Score = 27.6 bits (60), Expect = 4.3, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 30/102 (29%), Gaps = 8/102 (7%) Query: 105 ENQVMDFRTQLIRLCYSSDH-EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 QV + + + ++ D EK L +L G W G + Sbjct: 14 TEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFLN 73 Query: 164 TYDILDQNRIFDP-------KCLDEFPNLKAFMCRFEALEKI 198 + +P +++ LK + R EKI Sbjct: 74 VPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKI 115 >2CYA-A nrPDB Length = 364 Score = 27.6 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 15/37 (40%) Query: 14 IRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQW 50 IR A +R ++E E R+ E D+ W Sbjct: 91 IRAAARIVRRVMEAAGVPVERVRFVDAEELASDKDYW 127 >1NX8-A nrPDB Length = 273 Score = 27.6 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 22/57 (38%), Gaps = 1/57 (1%) Query: 30 TSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIAR 86 Y +++ G D + K K+ LP+ DG ++Q + + Y A Sbjct: 65 VEYADEKIGVG-FGYRDTLKLEGEKGKIVTGRGQLPFHADGGLLLSQVDQVFLYAAE 120 >4KWM-A nrPDB Length = 329 Score = 27.2 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 30/102 (29%), Gaps = 8/102 (7%) Query: 105 ENQVMDFRTQLIRLCYSSDH-EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFL 163 QV + + + ++ D EK L +L G W G + Sbjct: 17 TEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFIN 76 Query: 164 TYDILDQNRIFDP-------KCLDEFPNLKAFMCRFEALEKI 198 + +P +++ LK + R EKI Sbjct: 77 VPEWSYIVEKANPANDLCYPGNFNDYEELKHLLSRINHFEKI 118 >5WP9-A nrPDB Length = 710 Score = 26.8 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 5/55 (9%) Query: 15 RGLAHAIR--LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDV---KFKLDLDFPNL 64 RG R L+L+ S E+KR T GE + +W K KL DF + Sbjct: 53 RGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEI 107 >4BEJ-A nrPDB Length = 617 Score = 26.8 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 5/55 (9%) Query: 15 RGLAHAIR--LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDV---KFKLDLDFPNL 64 RG R L+L+ S E+KR T GE + +W K KL DF + Sbjct: 60 RGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEI 114 >3W6N-A nrPDB Length = 364 Score = 26.8 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 5/55 (9%) Query: 15 RGLAHAIR--LLLEFTDTSYEEKRYTCGEAPDYDRSQWLDV---KFKLDLDFPNL 64 RG R L+L+ S E+KR T GE + +W K KL DF + Sbjct: 55 RGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEI 109 >5Y7I-A nrPDB Length = 261 Score = 26.4 bits (57), Expect = 9.1, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 21/54 (38%), Gaps = 3/54 (5%) Query: 123 DHEKLKPQYLEELPGQLKQFS---MFLGKFSWFAGEKLTFVDFLTYDILDQNRI 173 + ++L LP ++ S + + + G++LT D L R+ Sbjct: 156 EFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRV 209 >2KEP-A nrPDB Length = 110 Score = 26.4 bits (57), Expect = 9.3, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 22/64 (34%), Gaps = 3/64 (4%) Query: 156 KLTFV--DFLTYDI-LDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPI 212 K+T D LD ++ + L+A + + + + + K+P+ Sbjct: 8 KVTVAKGDIKAIAAALDMYKLDNFAYPSTQQGLEALVKKPTGNPQPKNWNKDGYLKKLPV 67 Query: 213 NNKM 216 + Sbjct: 68 DPWG 71 >2X49-A nrPDB Length = 333 Score = 26.4 bits (57), Expect = 9.3, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 37/111 (33%), Gaps = 16/111 (14%) Query: 79 AILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQ 138 A+ RYI K GE +R ++ +V D + IR S L P+ L Sbjct: 221 AMARYICHKFANGGE-----LRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANLMDL 275 Query: 139 LK-QFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAF 188 + + L + D + +D R FP+L+ Sbjct: 276 ITLKLDDLL----------IAHKDLVLLTSVDVRRFIKKMIEGRFPDLEVL 316 >4G74-A nrPDB Length = 502 Score = 26.4 bits (57), Expect = 9.5, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 43/108 (39%), Gaps = 19/108 (17%) Query: 61 FPNLPYLLDGKNKITQ---SNAILRYIA---RKHNMCGETEEEKIRVDII---------- 104 F +P + D + + + S I R A K N+ + + E+ R+ I Sbjct: 172 FG-IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGV 230 Query: 105 --ENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFS 150 ++ D+ Q +R + E+++ +E LP L F L ++ Sbjct: 231 EAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 278 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.147 0.412 Lambda K H 0.267 0.0450 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,771,506 Number of Sequences: 36641 Number of extensions: 411881 Number of successful extensions: 1382 Number of sequences better than 10.0: 159 Number of HSP's better than 10.0 without gapping: 165 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 1032 Number of HSP's gapped (non-prelim): 226 length of query: 225 length of database: 10,336,785 effective HSP length: 94 effective length of query: 131 effective length of database: 6,892,531 effective search space: 902921561 effective search space used: 902921561 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.4 bits)