BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P21242 (288 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FGG-F nrPDB 597 e-171 6FVW-g nrPDB 509 e-145 6EPD-G nrPDB 260 4e-70 3H4P-A nrPDB 157 5e-39 6HE5-A nrPDB 145 2e-35 5FMG-G nrPDB 138 3e-33 5LF0-A nrPDB 136 1e-32 5GJR-F nrPDB 134 4e-32 2KU2-A nrPDB 134 4e-32 4FZC-A nrPDB 131 3e-31 5FMG-E nrPDB 128 4e-30 1G0U-D nrPDB 127 4e-30 2Z5C-C nrPDB 125 1e-29 5FMG-B nrPDB 122 2e-28 6J30-C nrPDB 121 4e-28 5LEZ-C nrPDB 121 4e-28 5FMG-C nrPDB 118 3e-27 4YA5-C nrPDB 118 4e-27 1IRU-A nrPDB 116 1e-26 5LE5-B nrPDB 112 2e-25 5FMG-D nrPDB 111 4e-25 5T0I-L nrPDB 108 4e-24 5L5W-G nrPDB 102 2e-22 3NZW-E nrPDB 100 7e-22 5FMG-F nrPDB 98 5e-21 5FMG-A nrPDB 84 6e-17 3IPM-H nrPDB 61 4e-10 6HEC-1 nrPDB 58 5e-09 3H4P-a nrPDB 55 3e-08 5FGI-H nrPDB 51 6e-07 6EPF-2 nrPDB 49 2e-06 3UNH-H nrPDB 48 4e-06 5L4G-8 nrPDB 47 8e-06 6AVO-B nrPDB 47 1e-05 5FMG-I nrPDB 47 1e-05 6HUB-H nrPDB 44 6e-05 6HV7-H nrPDB 42 4e-04 4ARF-A nrPDB 33 0.16 6GOP-M nrPDB 32 0.39 4AEZ-A nrPDB 32 0.40 2QIB-A nrPDB 32 0.44 6D03-A nrPDB 30 1.1 1XMS-A nrPDB 30 1.7 3UNF-K nrPDB 29 1.9 5FMG-L nrPDB 29 3.0 1Q5R-H nrPDB 28 3.9 3SBC-A nrPDB 28 4.9 4BDV-A nrPDB 27 6.9 2IQ7-A nrPDB 27 7.7 1AA3-A nrPDB 27 8.3 3WXR-K nrPDB 27 9.9 >5FGG-F nrPDB Length = 288 Score = 597 bits (1538), Expect = e-171, Method: Compositional matrix adjust. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV Sbjct: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV Sbjct: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 Query: 121 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV Sbjct: 121 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 Query: 181 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI 240 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI Sbjct: 181 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI 240 Query: 241 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE 288 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE Sbjct: 241 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE 288 >6FVW-g nrPDB Length = 245 Score = 509 bits (1311), Expect = e-145, Method: Compositional matrix adjust. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 4 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK 63 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK Sbjct: 1 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK 60 Query: 64 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH 123 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH Sbjct: 61 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH 120 Query: 124 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH 183 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH Sbjct: 121 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH 180 Query: 184 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA 243 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA Sbjct: 181 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA 240 Query: 244 QKEIN 248 QKEIN Sbjct: 241 QKEIN 245 >6EPD-G nrPDB Length = 255 Score = 260 bits (665), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 133/262 (50%), Positives = 179/262 (68%), Gaps = 8/262 (3%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M+SIGTGYDLS S FSPDGR FQVEYA+KAVEN +T+IGI+C DGVVF VEKL+ SKL Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 N ++ VDRH+G +GL+ D R L + REEA++F+ + IP+ ADR+ YV Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 Query: 121 QAHTLYNSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKL 179 A+TLY++VRPFG S + G N GA LYM++PSG +GY G A GK RQ+AK E+EKL Sbjct: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180 Query: 180 VDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEA 239 + ++ R+ VK+ AKIIY+ H++ K+K FELE+SW T G H+ V D+ +EA Sbjct: 181 ---QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVG-ELTKGRHEIVPKDVREEA 236 Query: 240 IDFAQKEINGDDDEDEDDSDNV 261 +A++ + +EDE D DN+ Sbjct: 237 EKYAKESLK---EEDESDDDNM 255 >3H4P-A nrPDB Length = 264 Score = 157 bits (397), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 86/211 (40%), Positives = 125/211 (59%), Gaps = 3/211 (1%) Query: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 10 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 69 Query: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 70 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 129 Query: 126 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 130 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 186 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEI 216 ++ E ++ A + A+ED K ++ ++ I Sbjct: 187 DITLDEGLELAITALTKANEDIKPENVDVCI 217 >6HE5-A nrPDB Length = 247 Score = 145 bits (367), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 77/172 (44%), Positives = 101/172 (58%), Gaps = 1/172 (0%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 GYD + +VFSPDGR FQVEYA +AV+ G T+IGIKC +GV+ +K + SKLL K Sbjct: 8 GYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADTIEK 67 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I +D HI SGL+ D R L++R R EA + Y PI + A ++ + Q +T Y Sbjct: 68 IYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQY 127 Query: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 VRPFGVS + GVD+ LY +PSG+ YK A G GR + EK Sbjct: 128 GGVRPFGVSLLIAGVDEV-PKLYETDPSGALLEYKATAIGMGRNAVTEFFEK 178 >5FMG-G nrPDB Length = 252 Score = 138 bits (348), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 136/253 (53%), Gaps = 11/253 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAV--EKLITSKL 58 M + GYDLS S FSPDGR +QVEY K++ N T++ ++C DG++ + +K+ Sbjct: 1 MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKM 60 Query: 59 LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQ 118 + +I V+ +I YSG D R++++R R EA ++ + T IP+ +R+ Sbjct: 61 IKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISL 120 Query: 119 YVQAHTLYNSVRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 Y+ A+TLY +RPF S I + K+ +Y +EP+G+ + Y G GK ++ K E+E Sbjct: 121 YIHAYTLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIE 180 Query: 178 KLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE--LEISW-CSLS--ETNGLHKFVK 232 K + ++ R+A++ K I + + + + + + SW C S E +H+ + Sbjct: 181 K---KDYKDINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEIL 237 Query: 233 GDLLQEAIDFAQK 245 L +A+++ +K Sbjct: 238 TPALNKAVEYIEK 250 >5LF0-A nrPDB Length = 234 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 78/214 (36%), Positives = 117/214 (54%), Gaps = 4/214 (1%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 GY S + FSP G+ Q+EYA+ AV G S+GIK +GVV A EK S L + K Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 ++ + +HIG VYSG+ PD R LV+R R+ A + +Y+ PIP R+ +Q +T Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186 VRPFGVS + G ++ +L+ +PSG+Y+ +K A GK + K LEK + E Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEK---RYNED 181 Query: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCS 220 L +A+ A + + E +D +E+ C+ Sbjct: 182 LELEDAIHTAILTLKESFEGQMTED-NIEVGICN 214 >5GJR-F nrPDB Length = 241 Score = 134 bits (338), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 77/233 (33%), Positives = 126/233 (54%), Gaps = 11/233 (4%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD + FSP+GR FQVEYA++A++ G+T+IGI+ ++GV AVEK ITS L+ P KI Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 +D HIGC SGLI D + L+++ R E + Y + + + + + Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127 Query: 128 S-----VRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH 182 + RPFGV+ +FGGVD+ G L+ ++PSG++ A G + A++ L+++ Sbjct: 128 ADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV--- 184 Query: 183 HPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDL 235 + + ++ +EA+K + I+ E EK I ++ H F K +L Sbjct: 185 YHKSMTLKEAIKSSLIILKQVME---EKLNATNIELATVQPGQNFHMFTKEEL 234 >2KU2-A nrPDB Length = 237 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 74/197 (37%), Positives = 115/197 (58%), Gaps = 3/197 (1%) Query: 13 SVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDR 72 +VFSPDGR FQVEYA +AV+ G+T++G+K +GV+ +K + S+L+ KIQ++D Sbjct: 17 TVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIEKIQLIDD 76 Query: 73 HIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPF 132 ++ V SGL+ D R LV+ R A K Y + + I R+ +Q +T Y VRP+ Sbjct: 77 YVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPY 136 Query: 133 GVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREA 192 GVS IF G+D+ G L+ +P+G+ YK A G G+ + + LE+ + E L +EA Sbjct: 137 GVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLER---EYKENLPEKEA 193 Query: 193 VKQAAKIIYLAHEDNKE 209 V K + + E+ +E Sbjct: 194 VTLGIKALKSSLEEGEE 210 >4FZC-A nrPDB Length = 250 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 73/173 (42%), Positives = 104/173 (60%), Gaps = 2/173 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 Y S + FSP G+ Q++YA+ AV+ G TS+GIK +GVV A EK +S L + + K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEA-ASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 ++ IG VYSG+ PD R LV++ R+ A S+K++Y P + + +Q T Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124 Query: 127 NSVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 VRPFGVS + G D+ NG LY ++PSGSY+ +K A GKG +AK LEK Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEK 177 >5FMG-E nrPDB Length = 256 Score = 128 bits (321), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 74/213 (34%), Positives = 119/213 (55%), Gaps = 10/213 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M S + YD + FSP+GR FQVEYA+ A++ G+T++GI NDGV+ A E+ I+S L+ Sbjct: 1 MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIE 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQY- 119 K+ +D HIGC SGL+ D R L++ R E +K +Y I I + + + + Sbjct: 61 KDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELA 120 Query: 120 VQAHTLYNS------VRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAK 173 + L +S RPFGV+ + GGVDKNG L+ EPSG+ + A+ G ++ A+ Sbjct: 121 LDFSNLSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAE 180 Query: 174 AELEKLVDHHPEGLSAREAVKQAAKIIYLAHED 206 L+ +++ + ++ +A A ++ ED Sbjct: 181 LLLQ---ENYKKDMTFEQAEILALTVLRQVMED 210 >1G0U-D nrPDB Length = 241 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 73/194 (37%), Positives = 104/194 (53%), Gaps = 7/194 (3%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD S FSP+GR FQVEY+++A++ G+T+IGI +GVV VEK TS LL KI Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 +DRHIGC SGL D R ++ R A + Y I + + + A + Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMS- 126 Query: 128 SVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186 RPFGV+ + G D +G L+ EPSG+++ Y A G G + A+AE L++ Sbjct: 127 --RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAE---LLNEWHSS 181 Query: 187 LSAREAVKQAAKII 200 L+ +EA KI+ Sbjct: 182 LTLKEAELLVLKIL 195 >2Z5C-C nrPDB Length = 262 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 78/201 (38%), Positives = 107/201 (53%), Gaps = 12/201 (5%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD S FSP+GR FQVEY+++A++ G+T+IGI +GVV VEK TS LL KI Sbjct: 10 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 69 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPA-------FADRLGQYV 120 +DRHIGC SGL D R ++ R A + Y I + + A R G+ Sbjct: 70 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 129 Query: 121 QAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKL 179 S RPFGV+ + G D +G L+ EPSG+++ Y A G G + A+AEL L Sbjct: 130 SGEERLMS-RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAEL--L 186 Query: 180 VDHHPEGLSAREAVKQAAKII 200 + H L+ +EA KI+ Sbjct: 187 NEWHS-SLTLKEAELLVLKIL 206 >5FMG-B nrPDB Length = 235 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 63/171 (36%), Positives = 94/171 (54%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 Y S + FSP G+ Q+EYA+ V + + ++GI+ +GV+ A EK ++L+ KI Sbjct: 6 YSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKI 65 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 Q + HIG VY+G+ D R L+ R R+EA + Y + I + + VQ T Sbjct: 66 QQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTG 125 Query: 128 SVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 VRPFG+S + GVD G HLY ++PSG Y+ + GK Q+ + LEK Sbjct: 126 GVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEK 176 >6J30-C nrPDB Length = 258 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 63/172 (36%), Positives = 97/172 (56%), Gaps = 2/172 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-K 66 YD ++FSP+GR +QVEYA++++ + T+IGI +DG+V A E+ +TS LL + K Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 + ++ I +GL D L+N R A ++ K Y IP+ RL Q +T + Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 127 NSVRPFGVSTIFGGV-DKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 +RPFGVS I+ G D+ G LY PSG+Y G+K + G +A+ L+ Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQ 177 >5LEZ-C nrPDB Length = 248 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 65/172 (37%), Positives = 98/172 (56%), Gaps = 1/172 (0%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + KI Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 +D ++ ++GL D R ++NR R E S + + P+ + + Q +T N Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 Query: 128 SVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 >5FMG-C nrPDB Length = 246 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 63/173 (36%), Positives = 98/173 (56%), Gaps = 2/173 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-K 66 YD + FSP+GR +QVEYA++A+ N + +IG+ DGV+ +K+ SKL+ N K Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I +D+HI C +GL D L+N+ R A + Y P+ ++ Q++T Y Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 127 NSVRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 +RP+GVS + GG D K+G LY +PSG+Y G+ A G +A + L++ Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQ 177 >4YA5-C nrPDB Length = 254 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 71/199 (35%), Positives = 102/199 (51%), Gaps = 9/199 (4%) Query: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKL----LVP 61 +GYD + S+FSPDG FQVEYA++AV+ GT ++G+K + VV E+ T KL + P Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61 Query: 62 QKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQ 121 K KI D H+ +SGL D R L+ + R EA S + + P+ + + Q Sbjct: 62 SKVSKI---DSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQ 118 Query: 122 AHTLYNSVRPFGVSTIFGGVDK--NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKL 179 +T VRPFGVST+ G D + LY EPSG Y + G+ ++ + LEK Sbjct: 119 RYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKN 178 Query: 180 VDHHPEGLSAREAVKQAAK 198 D + E VK + Sbjct: 179 YDRKEPPATVEECVKLTVR 197 >1IRU-A nrPDB Length = 246 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 2/176 (1%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAV-ENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65 G+D ++FSP+GR +QVEYA KA+ + G TS+ ++ D V +K + KLL Sbjct: 8 GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67 Query: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125 + + +IGCV +G+ D R V R R EAA++K Y IP+ R+ Q +T Sbjct: 68 HLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127 Query: 126 YNSVRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 +RP G I G+D + G +Y +P+G Y G+K A G + + + LEK V Sbjct: 128 NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKV 183 >5LE5-B nrPDB Length = 261 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/221 (33%), Positives = 118/221 (53%), Gaps = 6/221 (2%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQ-KNVK 66 YD ++FSP+GR +QVEYA++A+ + T +GI NDGV+ A E+ KLL + K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I ++ + C +G+ D L N R A + Y+ PIP L QA+T + Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 127 NSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 RPFGVS ++ G DK+ G LY +PSG+Y G+K G +A + L++ D+ Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQ--DYKEG 182 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNG 226 ++ + A+ A K++ + +K ++EI+ +L+ NG Sbjct: 183 EMTLKSALALAIKVLNKTMDVSKLSAEKVEIA--TLTRENG 221 >5FMG-D nrPDB Length = 241 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 67/196 (34%), Positives = 101/196 (51%), Gaps = 4/196 (2%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 YD + +VFSPDG QVE+A++AV+ G ++ IK ++ V AVEK KL P+ K Sbjct: 2 SYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEK 61 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 + +D H ++GL D R LVN+ R E + P P+ A + + Q T Sbjct: 62 LIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHR 121 Query: 127 NSVRPFGVSTIFGGVDKNG-AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 VRPFG++T+ G N +Y EPSG Y +K A GK + + LEK ++ E Sbjct: 122 GGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEK---NYQE 178 Query: 186 GLSAREAVKQAAKIIY 201 + ++ + A K I+ Sbjct: 179 NMEQKDCIFLALKAIF 194 >5T0I-L nrPDB Length = 268 Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 2/171 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD +V+SP GR Q+EYA++AV+ G+ ++G+K V K S+L QK KI Sbjct: 11 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQK--KI 68 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 VD HIG +GL D R L N R+E + ++ P+P+ +G Q T Sbjct: 69 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 128 Query: 128 SVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 RP+GV + G D G H++ PS +Y+ + + G QSA+ LE+ Sbjct: 129 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLER 179 >5L5W-G nrPDB Length = 252 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 64/172 (37%), Positives = 88/172 (51%), Gaps = 2/172 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAV-ENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 YD ++FSP+GR +QVEYA KA + S+ ++ D V +K + KLL P Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I + R IG V +G IPD R+ R + EAA F+ Y +P A R+ Q +T Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 127 NSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 +RP GV F VD+ G +Y +P+G Y GYK ATG +Q LE Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLE 183 >3NZW-E nrPDB Length = 234 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 2/174 (1%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD FSP GR FQVEYA++A++ G+ ++G++ N V K +L QK KI Sbjct: 6 YDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQK--KI 63 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 D H+G +GL PD R L N R++ ++ + + L Q +T Sbjct: 64 IKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSY 123 Query: 128 SVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVD 181 RP+GV + G DK+GAHL +PSG+ G A G Q AK LE+ +D Sbjct: 124 GGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLD 177 >5FMG-F nrPDB Length = 254 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 123/253 (48%), Gaps = 8/253 (3%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD N ++SP+GR +QVEYA +A++ GT ++ IK D VV + K SKL PQ+ KI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQE--KI 63 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 +D +IG SG+ D + L + E S K LY I I + + Q +T + Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 128 SVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGL 187 S R FGV + N ++ P+GSY+ Y + G ++K LEK + H E Sbjct: 124 SKRAFGVGLMIAAYH-NEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNL-HLFEEC 181 Query: 188 SAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEI 247 S E + K A + + + EL IS +L+ H + + LQ ++ ++ Sbjct: 182 SLEELILHCLK----ALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKM 237 Query: 248 NGDDDEDEDDSDN 260 + + ++ E++ N Sbjct: 238 DAEQEQVEENVQN 250 >5FMG-A nrPDB Length = 260 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 58/190 (30%), Positives = 94/190 (49%), Gaps = 12/190 (6%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVEN-GTTSIGIKC-NDGVVFAVEKLITS-----KLLV 60 YD ++FSPDG +Q+EYA+KAV+N TS+G+K N V+ + +K+ T KLL Sbjct: 9 YDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLD 68 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPA--FADRLGQ 118 I + IGC G+ D +V + R EA+ F LY + A + Sbjct: 69 YNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEF--LYSNGYNVNAETLCRNICD 126 Query: 119 YVQAHTLYNSVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 +Q +T + +R S + G+D+N L+ +PSG GY+ G Q + + LE Sbjct: 127 KIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLE 186 Query: 178 KLVDHHPEGL 187 +L++ + + Sbjct: 187 RLLEKRKKKI 196 >3IPM-H nrPDB Length = 217 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 47/180 (26%), Positives = 83/180 (46%), Gaps = 13/180 (7%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN-VKIQVVDRHIGCVYSGLIPDGRH 87 + +E GTT++GI D V+ A E+ +T + + KN K+ +D + G +GL+ D + Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVR--PFGVSTIFGGVDKNG 145 LV + E ++ + +PI A A L + N V+ P+ V + GG+D Sbjct: 63 LVRYMKAELELYRLQRRVNMPIEAVATLLSN------MLNQVKYMPYMVQLLVGGID-TA 115 Query: 146 AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 H++ ++ +G A+TG G LE + E ++ E V + I A + Sbjct: 116 PHVFSIDAAGGSVEDIYASTGSGSPFVYGVLE---SQYSEKMTVDEGVDLVIRAISAAKQ 172 >6HEC-1 nrPDB Length = 202 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK--IQVVDRHIGCVYSGLIPDGRHLVNRG 92 TT++G+ C DGVV A EK T + K K Q+ DR + +G + D + L Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADR-MAMTTAGSVGDAQFLARII 59 Query: 93 REEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVR--PFGVSTIFGGVDKNGAHLYM 150 + EA ++ + + A A L NS R P+ V + GG+D G +Y Sbjct: 60 KIEANLYEIRRERKPTVRAIA------TLTSNLLNSYRYFPYLVQLLIGGIDSEGKSIYS 113 Query: 151 LEPSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 ++P G K ATG G +A LE D + EAV+ A + IY A + Sbjct: 114 IDPIGGAIEEKDIVATGSGSLTAYGVLE---DRFTPEIGVDEAVELAVRAIYSAMK 166 >3H4P-a nrPDB Length = 219 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 52/174 (29%), Positives = 76/174 (43%), Gaps = 10/174 (5%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHLYMLE 152 EA +K IP A A L + + ++ PF I GG D GA L+ L+ Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKLFSLD 117 Query: 153 PSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 P G K ATG G A LE D +S E +K A + A E Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD---MSVEEGIKLALNALKSAME 168 >5FGI-H nrPDB Length = 244 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 49/193 (25%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 KA G T +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTE- 65 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRP---------------- 131 A +G ++ H+LY S P Sbjct: 66 -----------------------AVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY 102 Query: 132 ---FGVSTIFGGVDKNGAHLYMLEPSGSY-WGYKGAATGKGRQSAKAELEKLVDHHPEGL 187 G I GVD G+HL+ + GS GY + G G +A A LE H + L Sbjct: 103 QGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYY-LSLGSGSLAAMAVLE---SHWKQDL 158 Query: 188 SAREAVKQAAKII 200 + EA+K A+ I Sbjct: 159 TKEEAIKLASDAI 171 >6EPF-2 nrPDB Length = 277 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 12/172 (6%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDG-- 85 KA + GTT G+ DG+V + T ++V KN KI + +I C +G D Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 86 -RHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN 144 L++ E L +P A+R+ + L+ G + + GGVD Sbjct: 98 TTQLISSNLE----LHSLTTGRLPRVVTANRMLK----QMLFRYQGYIGAALVLGGVDVT 149 Query: 145 GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQA 196 G HLY + P GS G G +A A E E A++ V +A Sbjct: 150 GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEA 201 >3UNH-H nrPDB Length = 234 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 60/144 (41%), Gaps = 6/144 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D + R Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAAD-TEMTTRMA 59 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 L P A R+ + TL+ G S + GGVD NG LY + P Sbjct: 60 ASKMELHALSTGREPRVATVTRILR----QTLFRYQGHVGASLVVGGVDLNGPQLYEVHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELE 177 GSY A G G+ +A A LE Sbjct: 116 HGSYSRLPFTALGSGQGAAVALLE 139 >5L4G-8 nrPDB Length = 277 Score = 47.4 bits (111), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 12/153 (7%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDG-- 85 K + GTT G+ DG+V + T ++V KN KI + +I C +G D Sbjct: 38 KVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 86 -RHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN 144 L++ E L +P A+R+ + L+ G + + GGVD Sbjct: 98 TTQLISSNLE----LHSLSTGRLPRVVTANRMLK----QMLFRYQGYIGAALVLGGVDVT 149 Query: 145 GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 G HLY + P GS G G +A A E Sbjct: 150 GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFE 182 >6AVO-B nrPDB Length = 234 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 58/144 (40%), Gaps = 6/144 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D + R Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADA-EMTTRMV 59 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 L P A R + TL+ G S I GGVD G LY + P Sbjct: 60 ASKMELHALSTGREPRVATVTR----ILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELE 177 GSY A G G+ +A A LE Sbjct: 116 HGSYSRLPFTALGSGQDAALAVLE 139 >5FMG-I nrPDB Length = 229 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 6/144 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ C + V+ + T +V KN K+ + ++I C +G+ D H + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + T + RL Q + + Y + + GGVD NG LY + P Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVC-----AIVLGGVDVNGPQLYGIHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELE 177 GS A G G +A A LE Sbjct: 116 HGSSCLLPFTALGSGSLNAMAVLE 139 >6HUB-H nrPDB Length = 234 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 12/147 (8%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDG---RHLVN 90 TT G+ DG+V + T ++V KN KI + +I C +G D L++ Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 91 RGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYM 150 E L +P A+R+ + L+ G + + GGVD G HLY Sbjct: 61 SNLE----LHSLSTGRLPRVVTANRMLK----QMLFRYQGYIGAALVLGGVDVTGPHLYS 112 Query: 151 LEPSGSYWGYKGAATGKGRQSAKAELE 177 + P GS G G +A A E Sbjct: 113 IYPHGSTDKLPYVTMGSGSLAAMAVFE 139 >6HV7-H nrPDB Length = 226 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 49/173 (28%), Positives = 73/173 (42%), Gaps = 21/173 (12%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGR---HLVN 90 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D L+ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 91 RGREEAASFKKLY--KTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHL 148 E LY + P + A Q ++ H L+ G I GVD G+HL Sbjct: 61 SNIE----LHSLYTSREPRVVSAL-----QMLKQH-LFKYQGHIGAYLIVAGVDPTGSHL 110 Query: 149 YMLEPSGSY-WGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII 200 + + GS GY + G G +A A LE H + L+ EA+K A+ I Sbjct: 111 FSIHAHGSTDVGYY-LSLGSGSLAAMAVLE---SHWKQDLTKEEAIKLASDAI 159 >4ARF-A nrPDB Length = 394 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Query: 125 LYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH-H 183 +YNS + ++++ G D N +Y +EP G+++ Y+ A Q + LE+L H + Sbjct: 77 IYNSPEEYKLNSVLYGYDTNNGGMY-IEPEGTFFTYEREA-----QESTYTLEELFRHEY 130 Query: 184 PEGLSAREAV 193 L R AV Sbjct: 131 THYLQGRYAV 140 >6GOP-M nrPDB Length = 246 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 91/205 (44%), Gaps = 25/205 (12%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK--IQVVDRHIGCVYSGLIPDGR 86 + + GT+ I +K ++GV+ A + L + L+ V+ I V D + + SG I D + Sbjct: 16 QPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGI-SGDISDMQ 74 Query: 87 HLVNRGREEAASFKKLYKTPIP------IPAFADRLGQYVQAHTLY---NSVRPFGVSTI 137 H + R ++ + + Y P+ P++ + +Y+ A +Y + + P + I Sbjct: 75 H-IERLLKDLVT-ENAYDNPLADAEEALEPSY---IFEYL-ATVMYQRRSKMNPLWNAII 128 Query: 138 FGGVDKNG-AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH---PEGL--SARE 191 GV NG L + G + ATG G A L K+VD P+ A E Sbjct: 129 VAGVQSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEE 188 Query: 192 AVKQAAKIIYLAHEDNKEKDFELEI 216 A+ A +++Y + ++F L I Sbjct: 189 AIVNAMRVLYY-RDARSSRNFSLAI 212 >4AEZ-A nrPDB Length = 401 Score = 31.6 bits (70), Expect = 0.40, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 7/52 (13%) Query: 63 KNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLY-----KTPIPI 109 K V I D + +YS L PDGR L +E F ++Y K PIPI Sbjct: 341 KQVDIPAHDTRV--LYSALSPDGRILSTAASDENLKFWRVYDGDHVKRPIPI 390 >2QIB-A nrPDB Length = 231 Score = 31.6 bits (70), Expect = 0.44, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Query: 191 EAVKQAAKIIYLAHEDNKEKDFELEI---SWCSLSETNGL 227 ++V+QAA + L+H D E LE+ SW SL+E+ L Sbjct: 126 DSVRQAAYVQILSHLDVTEPPARLELVVRSWISLAESTAL 165 >6D03-A nrPDB Length = 659 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 18/29 (62%) Query: 141 VDKNGAHLYMLEPSGSYWGYKGAATGKGR 169 VDKNG +Y++E G Y Y AAT G+ Sbjct: 102 VDKNGRLVYLVENPGGYVAYSKAATVTGK 130 >1XMS-A nrPDB Length = 356 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 9/81 (11%) Query: 145 GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAH 204 G ++E +G+++ YKG G+G+ +A A L+ +PE +A+E K+ ++ L Sbjct: 282 GVKEKLIEKAGAWYSYKGEKIGQGKANATAWLK----DNPE--TAKEIEKKVREL--LLS 333 Query: 205 EDNKEKDFELEISWCSLSETN 225 N DF ++ S ++ETN Sbjct: 334 NPNSTPDFSVDDSE-GVAETN 353 >3UNF-K nrPDB Length = 204 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 39/177 (22%), Positives = 73/177 (41%), Gaps = 13/177 (7%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ AV+ T+ + + K+ ++ ++ SG D ++ Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVS--TIFGGVDKNGAHLYML 151 +E + I + A + L + + R G+S ++ G DK G LY + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAK-IIYLAHEDN 207 + +G+ + +TG G A ++ + + LS EA + I Y H DN Sbjct: 115 DDNGTRLSGQMFSTGSGNTYAYGVMD---SGYRQDLSPEEAYDLGRRAIAYATHRDN 168 >5FMG-L nrPDB Length = 211 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 39/178 (21%), Positives = 75/178 (42%), Gaps = 24/178 (13%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K DG++ AV+ + + +NV KI ++++I +G G Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAG-----------GA 49 Query: 94 EEAASFKKLYKTPIPIPAFAD------RLGQYVQAHTLYNSVRPFGVST--IFGGVDKNG 145 + ++K I I + R + ++ LY + +G+ I G D G Sbjct: 50 ADCLYWEKYLGKIIKIYELRNNEKISVRAASTILSNILY-QYKGYGLCCGIILSGYDHTG 108 Query: 146 AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 +++ ++ SG + G G A + L+ D++ L+ +AV+ A IY A Sbjct: 109 FNMFYVDDSGKKVEGNLFSCGSGSTYAYSILDSAYDYN---LNLDQAVELARNAIYHA 163 >1Q5R-H nrPDB Length = 294 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 1/92 (1%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK-IQVVDRHIGCVYSGLIPDGRHLVNR 91 +GTT + + GV+ A ++ T L+ ++V+ + V D + +G LV Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAH 123 E ++K+ P+ A+RL V+ + Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGN 155 >3SBC-A nrPDB Length = 216 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 10/22 (45%), Positives = 17/22 (77%) Query: 80 GLIPDGRHLVNRGREEAASFKK 101 GL+P G H+V + +++A +FKK Sbjct: 13 GLVPRGSHMVAQVQKQAPTFKK 34 >4BDV-A nrPDB Length = 760 Score = 27.3 bits (59), Expect = 6.9, Method: Compositional matrix adjust. Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 13/143 (9%) Query: 134 VSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEK-LVDHHPEGLSAREA 192 + T+ G V+++ L YW G T S E LV +H R+A Sbjct: 231 MHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNH------RQA 284 Query: 193 VKQAAKIIYLAHEDNKEKDFELEISWCSLS--ETNGLHKFVKGDLLQEAIDFAQKEINGD 250 + + I +L + D + +C +S + +G+ +VK D E K Sbjct: 285 SLEISPITFLTAQ-TLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEA 343 Query: 251 DDEDEDDSD---NVMSSDDENAP 270 +D D+D +D +V+ DD+N+P Sbjct: 344 EDYDDDLTDSEMDVVRFDDDNSP 366 >2IQ7-A nrPDB Length = 339 Score = 27.3 bits (59), Expect = 7.7, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Query: 134 VSTIFGGVDKNGAHLYMLEPSG--SYWGYKGAATGKGRQSAKAE 175 +S I G V +G ++Y+L SG S W + G + G++S K Sbjct: 286 LSKITGSVASSGTNVYILCASGACSNWKWSGVSVTGGKKSTKCS 329 >1AA3-A nrPDB Length = 63 Score = 27.3 bits (59), Expect = 8.3, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 32/51 (62%), Gaps = 6/51 (11%) Query: 150 MLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII 200 ++E +G+++ YKG G+G+ +A A L+ +PE +A+E K+ +++ Sbjct: 16 LIEKAGAWYSYKGEKIGQGKANATAWLK----DNPE--TAKEIEKKVRELL 60 >3WXR-K nrPDB Length = 238 Score = 26.9 bits (58), Expect = 9.9, Method: Compositional matrix adjust. Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 33/161 (20%) Query: 38 IGIKCNDGVVFAVEKLITSKL-LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVN--RGRE 94 +GI+ D V+ A K +T + ++ + K + + H ++G D + Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 95 EAASFKKLYK-TPIPIPAFADR-LGQYVQAHTLYNSVRPFGVSTIFGGVD--KNGAHLYM 150 + S ++ Y+ +P + +F + L + ++ S RP+ V+ + GG D KN LY Sbjct: 65 QLYSIREDYELSPQAVSSFVRQELAKSIR------SRRPYQVNVLIGGYDKKKNKPELYQ 118 Query: 151 LE--------PSGSYWGYKGAATGKGRQSAKAELEKLVDHH 183 ++ P G++ GY G T L+DHH Sbjct: 119 IDYLGTKVELPYGAH-GYSGFYTF-----------SLLDHH 147 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FGG-F nrPDB 414 e-116 6FVW-g nrPDB 340 4e-94 6EPD-G nrPDB 306 5e-84 3H4P-A nrPDB 289 1e-78 5GJR-F nrPDB 274 2e-74 5FMG-F nrPDB 274 3e-74 6HE5-A nrPDB 274 3e-74 5LF0-A nrPDB 264 2e-71 5LE5-B nrPDB 261 2e-70 5FMG-E nrPDB 259 1e-69 2Z5C-C nrPDB 259 1e-69 1G0U-D nrPDB 258 1e-69 5FMG-G nrPDB 256 1e-68 4YA5-C nrPDB 254 3e-68 2KU2-A nrPDB 253 6e-68 5FMG-C nrPDB 251 3e-67 5FMG-B nrPDB 249 1e-66 5LEZ-C nrPDB 247 4e-66 1IRU-A nrPDB 245 1e-65 5FMG-D nrPDB 244 2e-65 5T0I-L nrPDB 243 6e-65 6J30-C nrPDB 242 1e-64 4FZC-A nrPDB 236 9e-63 3NZW-E nrPDB 224 4e-59 5FMG-A nrPDB 209 1e-54 5L5W-G nrPDB 205 1e-53 6EPF-2 nrPDB 169 2e-42 5FMG-I nrPDB 168 3e-42 3UNH-H nrPDB 165 2e-41 5L4G-8 nrPDB 165 2e-41 6AVO-B nrPDB 165 3e-41 3H4P-a nrPDB 163 7e-41 5FGI-H nrPDB 162 2e-40 3IPM-H nrPDB 162 2e-40 6HEC-1 nrPDB 159 1e-39 6HUB-H nrPDB 157 4e-39 6HV7-H nrPDB 155 2e-38 Sequences not found previously or not previously below threshold: 6EPF-5 nrPDB 104 4e-23 5LN3-5 nrPDB 102 2e-22 5L5A-K nrPDB 99 3e-21 5FMG-L nrPDB 98 4e-21 3UNB-K nrPDB 98 5e-21 5L64-K nrPDB 97 6e-21 6EPC-1 nrPDB 97 8e-21 3UNF-K nrPDB 97 1e-20 5GJQ-a nrPDB 95 4e-20 6AVO-C nrPDB 94 5e-20 3NZW-K nrPDB 92 3e-19 5LEZ-N nrPDB 89 2e-18 5CZ8-K nrPDB 89 2e-18 5FGE-J nrPDB 88 6e-18 3WXR-K nrPDB 87 7e-18 5MPC-h nrPDB 86 1e-17 3NZW-L nrPDB 86 2e-17 5FMG-M nrPDB 80 9e-16 6AVO-A nrPDB 78 4e-15 1Q5R-H nrPDB 77 8e-15 5FMG-K nrPDB 76 2e-14 3UNF-N nrPDB 76 2e-14 1Q5Q-H nrPDB 76 2e-14 5L4G-U nrPDB 76 2e-14 5VFT-S nrPDB 75 2e-14 6EPF-6 nrPDB 74 6e-14 5FMG-H nrPDB 72 2e-13 2JAY-A nrPDB 64 6e-11 5LF3-J nrPDB 61 5e-10 4Y8P-I nrPDB 61 7e-10 5FMG-J nrPDB 61 7e-10 5LZP-A nrPDB 59 3e-09 5FMG-N nrPDB 59 3e-09 3UNE-I nrPDB 57 7e-09 6GOP-M nrPDB 55 5e-08 4HO7-A nrPDB 51 5e-07 5LF6-M nrPDB 48 3e-06 5GJQ-g nrPDB 48 3e-06 6EPE-7 nrPDB 48 6e-06 5NYW-A nrPDB 37 0.015 6DTT-A nrPDB 36 0.018 5LOY-A nrPDB 36 0.021 5JI2-A nrPDB 35 0.043 2FU0-A nrPDB 32 0.22 2GHB-A nrPDB 32 0.33 3QBR-A nrPDB 32 0.39 5EKZ-A nrPDB 31 0.63 1XF1-A nrPDB 29 2.5 4W8N-A nrPDB 28 3.3 2RGO-A nrPDB 28 3.5 3QQE-A nrPDB 28 4.2 2WR7-A nrPDB 28 4.2 3P1W-A nrPDB 28 4.3 2WR0-A nrPDB 28 5.2 2BTY-A nrPDB 27 9.9 >5FGG-F nrPDB Length = 288 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV Sbjct: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV Sbjct: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 Query: 121 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV Sbjct: 121 QAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 Query: 181 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI 240 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI Sbjct: 181 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAI 240 Query: 241 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE 288 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE Sbjct: 241 DFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE 288 >6FVW-g nrPDB Length = 245 Score = 340 bits (872), Expect = 4e-94, Method: Composition-based stats. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 4 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK 63 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK Sbjct: 1 IGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK 60 Query: 64 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH 123 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH Sbjct: 61 NVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAH 120 Query: 124 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH 183 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH Sbjct: 121 TLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH 180 Query: 184 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA 243 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA Sbjct: 181 PEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFA 240 Query: 244 QKEIN 248 QKEIN Sbjct: 241 QKEIN 245 >6EPD-G nrPDB Length = 255 Score = 306 bits (785), Expect = 5e-84, Method: Composition-based stats. Identities = 133/262 (50%), Positives = 179/262 (68%), Gaps = 8/262 (3%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M+SIGTGYDLS S FSPDGR FQVEYA+KAVEN +T+IGI+C DGVVF VEKL+ SKL Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 N ++ VDRH+G +GL+ D R L + REEA++F+ + IP+ ADR+ YV Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 Query: 121 QAHTLYNSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKL 179 A+TLY++VRPFG S + G N GA LYM++PSG +GY G A GK RQ+AK E+EKL Sbjct: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180 Query: 180 VDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEA 239 + ++ R+ VK+ AKIIY+ H++ K+K FELE+SW T G H+ V D+ +EA Sbjct: 181 ---QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVG-ELTKGRHEIVPKDVREEA 236 Query: 240 IDFAQKEINGDDDEDEDDSDNV 261 +A++ + +EDE D DN+ Sbjct: 237 EKYAKESLK---EEDESDDDNM 255 >3H4P-A nrPDB Length = 264 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 86/222 (38%), Positives = 128/222 (57%), Gaps = 3/222 (1%) Query: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 10 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 69 Query: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 70 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 129 Query: 126 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 130 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 186 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGL 227 ++ E ++ A + A+ED K ++ ++ I ++ + Sbjct: 187 DITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKI 228 >5GJR-F nrPDB Length = 241 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 129/242 (53%), Gaps = 11/242 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M + YD + FSP+GR FQVEYA++A++ G+T+IGI+ ++GV AVEK ITS L+ Sbjct: 1 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 P KI +D HIGC SGLI D + L+++ R E + Y + + + + Sbjct: 61 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA 120 Query: 121 QAHTLYNS-----VRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAE 175 ++ RPFGV+ +FGGVD+ G L+ ++PSG++ A G + A++ Sbjct: 121 LQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSS 180 Query: 176 LEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDL 235 L+++ + + ++ +EA+K + I+ E EK I ++ H F K +L Sbjct: 181 LQEV---YHKSMTLKEAIKSSLIILKQVME---EKLNATNIELATVQPGQNFHMFTKEEL 234 Query: 236 LQ 237 + Sbjct: 235 EE 236 >5FMG-F nrPDB Length = 254 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 121/253 (47%), Gaps = 8/253 (3%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD N ++SP+GR +QVEYA +A++ GT ++ IK D VV + K SKL PQ KI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ--EKI 63 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 +D +IG SG+ D + L + E S K LY I I + + Q +T + Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 128 SVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGL 187 S R FGV + N ++ P+GSY+ Y + G ++K LEK + H E Sbjct: 124 SKRAFGVGLMIAAYH-NEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNL-HLFEEC 181 Query: 188 SAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEI 247 S E + K + + + EL IS +L+ H + + LQ ++ ++ Sbjct: 182 SLEELILHCLKALK----CSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKM 237 Query: 248 NGDDDEDEDDSDN 260 + + ++ E++ N Sbjct: 238 DAEQEQVEENVQN 250 >6HE5-A nrPDB Length = 247 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 84/243 (34%), Positives = 125/243 (51%), Gaps = 5/243 (2%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 GYD + +VFSPDGR FQVEYA +AV+ G T+IGIKC +GV+ +K + SKLL K Sbjct: 8 GYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADTIEK 67 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I +D HI SGL+ D R L++R R EA + Y PI + A ++ + Q +T Y Sbjct: 68 IYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQY 127 Query: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186 VRPFGVS + GVD+ LY +PSG+ YK A G GR + EK + + Sbjct: 128 GGVRPFGVSLLIAGVDEV-PKLYETDPSGALLEYKATAIGMGRNAVTEFFEK---EYRDD 183 Query: 187 LSAREAVKQAAKIIYLAHE-DNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 245 LS +A+ + L+ E + ++ E+ + ++ A + ++ Sbjct: 184 LSFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANERIRE 243 Query: 246 EIN 248 + Sbjct: 244 LLK 246 >5LF0-A nrPDB Length = 234 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 81/230 (35%), Positives = 121/230 (52%), Gaps = 4/230 (1%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 GY S + FSP G+ Q+EYA+ AV G S+GIK +GVV A EK S L + K Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 ++ + +HIG VYSG+ PD R LV+R R+ A + +Y+ PIP R+ +Q +T Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186 VRPFGVS + G ++ +L+ +PSG+Y+ +K A GK + K LEK + E Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEK---RYNED 181 Query: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLL 236 L +A+ A + + E +D +E+ C+ + L D L Sbjct: 182 LELEDAIHTAILTLKESFEGQMTED-NIEVGICNEAGFRRLTPTEVKDYL 230 >5LE5-B nrPDB Length = 261 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 73/221 (33%), Positives = 118/221 (53%), Gaps = 6/221 (2%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQK-NVK 66 YD ++FSP+GR +QVEYA++A+ + T +GI NDGV+ A E+ KLL + K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I ++ + C +G+ D L N R A + Y+ PIP L QA+T + Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 127 NSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 RPFGVS ++ G DK+ G LY +PSG+Y G+K G +A + L++ D+ Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQ--DYKEG 182 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNG 226 ++ + A+ A K++ + +K ++EI+ +L+ NG Sbjct: 183 EMTLKSALALAIKVLNKTMDVSKLSAEKVEIA--TLTRENG 221 >5FMG-E nrPDB Length = 256 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 77/223 (34%), Positives = 122/223 (54%), Gaps = 11/223 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M S + YD + FSP+GR FQVEYA+ A++ G+T++GI NDGV+ A E+ I+S L+ Sbjct: 1 MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIE 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 K+ +D HIGC SGL+ D R L++ R E +K +Y I I + + + + Sbjct: 61 KDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELA 120 Query: 121 QAH-TLYNSV------RPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAK 173 L +S RPFGV+ + GGVDKNG L+ EPSG+ + A+ G ++ A+ Sbjct: 121 LDFSNLSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAE 180 Query: 174 AELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEI 216 L+ +++ + ++ +A A ++ ED K +EI Sbjct: 181 LLLQ---ENYKKDMTFEQAEILALTVLRQVMED-KLSTSNVEI 219 >2Z5C-C nrPDB Length = 262 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 79/262 (30%), Positives = 127/262 (48%), Gaps = 11/262 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M + YD S FSP+GR FQVEY+++A++ G+T+IGI +GVV VEK TS LL Sbjct: 3 MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLE 62 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 KI +DRHIGC SGL D R ++ R A + Y I + + + Sbjct: 63 SDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLA 122 Query: 121 QAHTLYNS------VRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAK 173 S RPFGV+ + G D +G L+ EPSG+++ Y A G G + A+ Sbjct: 123 LRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQ 182 Query: 174 AELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKG 233 AEL ++ L+ +EA KI+ E+ +++ ++S + + ++ K Sbjct: 183 AEL---LNEWHSSLTLKEAELLVLKILKQVMEEKLDENNA-QLSCITKQDGFKIYDNEKT 238 Query: 234 DLLQEAIDFAQKEINGDDDEDE 255 L + + + + ++ + E Sbjct: 239 AELIKELKEKEAAESPEEADVE 260 >1G0U-D nrPDB Length = 241 Score = 258 bits (660), Expect = 1e-69, Method: Composition-based stats. Identities = 78/247 (31%), Positives = 122/247 (49%), Gaps = 10/247 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60 M + YD S FSP+GR FQVEY+++A++ G+T+IGI +GVV VEK TS LL Sbjct: 1 MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLE 60 Query: 61 PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYV 120 KI +DRHIGC SGL D R ++ R A + Y I + + + Sbjct: 61 SDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLA 120 Query: 121 QAHTLYNSVRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKL 179 A + RPFGV+ + G D +G L+ EPSG+++ Y A G G + A+AEL Sbjct: 121 AAAAMS---RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAEL--- 174 Query: 180 VDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEA 239 ++ L+ +EA KI+ E+ +++ +++ +G + + Sbjct: 175 LNEWHSSLTLKEAELLVLKILKQVMEEKLDENNA---QLSCITKQDGFKIYDNEKTAELI 231 Query: 240 IDFAQKE 246 + +KE Sbjct: 232 KELKEKE 238 >5FMG-G nrPDB Length = 252 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 136/253 (53%), Gaps = 11/253 (4%) Query: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAV--EKLITSKL 58 M + GYDLS S FSPDGR +QVEY K++ N T++ ++C DG++ + +K+ Sbjct: 1 MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKM 60 Query: 59 LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQ 118 + +I V+ +I YSG D R++++R R EA ++ + T IP+ +R+ Sbjct: 61 IKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISL 120 Query: 119 YVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 Y+ A+TLY +RPF S I ++ + +Y +EP+G+ + Y G GK ++ K E+E Sbjct: 121 YIHAYTLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIE 180 Query: 178 KLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE--LEISW-CSLS--ETNGLHKFVK 232 K + ++ R+A++ K I + + + + + + SW C S E +H+ + Sbjct: 181 K---KDYKDINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEIL 237 Query: 233 GDLLQEAIDFAQK 245 L +A+++ +K Sbjct: 238 TPALNKAVEYIEK 250 >4YA5-C nrPDB Length = 254 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 71/218 (32%), Positives = 108/218 (49%), Gaps = 6/218 (2%) Query: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQ-KN 64 +GYD + S+FSPDG FQVEYA++AV+ GT ++G+K + VV E+ T KL + Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61 Query: 65 VKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHT 124 K+ +D H+ +SGL D R L+ + R EA S + + P+ + + Q +T Sbjct: 62 SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121 Query: 125 LYNSVRPFGVSTIFGGVDK--NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH 182 VRPFGVST+ G D + LY EPSG Y + G+ ++ + LEK D Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181 Query: 183 HPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCS 220 + E VK + + E + +EI+ Sbjct: 182 KEPPATVEECVKLTVRSL---LEVVQTGAKNIEITVVK 216 >2KU2-A nrPDB Length = 237 Score = 253 bits (647), Expect = 6e-68, Method: Composition-based stats. Identities = 74/200 (37%), Positives = 116/200 (58%), Gaps = 3/200 (1%) Query: 10 LSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQV 69 + +VFSPDGR FQVEYA +AV+ G+T++G+K +GV+ +K + S+L+ KIQ+ Sbjct: 14 RAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIEKIQL 73 Query: 70 VDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSV 129 +D ++ V SGL+ D R LV+ R A K Y + + I R+ +Q +T Y V Sbjct: 74 IDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGV 133 Query: 130 RPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSA 189 RP+GVS IF G+D+ G L+ +P+G+ YK A G G+ + + LE+ + E L Sbjct: 134 RPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLER---EYKENLPE 190 Query: 190 REAVKQAAKIIYLAHEDNKE 209 +EAV K + + E+ +E Sbjct: 191 KEAVTLGIKALKSSLEEGEE 210 >5FMG-C nrPDB Length = 246 Score = 251 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 126/244 (51%), Gaps = 6/244 (2%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV-PQKNVK 66 YD + FSP+GR +QVEYA++A+ N + +IG+ DGV+ +K+ SKL+ K Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I +D+HI C +GL D L+N+ R A + Y P+ ++ Q++T Y Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 127 NSVRPFGVSTIFGGVD-KNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 +RP+GVS + GG D K+G LY +PSG+Y G+ A G +A + L++ Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQ---EWKN 181 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAID-FAQ 244 ++ E + A K + + + K ++E+++ + + K++ ++E I + Q Sbjct: 182 DMTLEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQ 241 Query: 245 KEIN 248 K I Sbjct: 242 KYIK 245 >5FMG-B nrPDB Length = 235 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 69/213 (32%), Positives = 113/213 (53%), Gaps = 4/213 (1%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 Y S + FSP G+ Q+EYA+ V + + ++GI+ +GV+ A EK ++L+ K Sbjct: 5 EYSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFK 64 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 IQ + HIG VY+G+ D R L+ R R+EA + Y + I + + VQ T Sbjct: 65 IQQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQT 124 Query: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186 VRPFG+S + GVD G HLY ++PSG Y+ + GK Q+ + LEK + + Sbjct: 125 GGVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEK---RYNKD 181 Query: 187 LSAREAVKQAAKIIYLAHEDN-KEKDFELEISW 218 + +A+ A + ++E EK+ E+ +++ Sbjct: 182 IEIEDAIHTAILTLKESYEGVLNEKNIEIGVAY 214 >5LEZ-C nrPDB Length = 248 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 70/231 (30%), Positives = 112/231 (48%), Gaps = 9/231 (3%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + K Sbjct: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I +D ++ ++GL D R ++NR R E S + + P+ + + Q +T Sbjct: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 Query: 127 NSVRPFGVSTIFGGVDKNG-AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 N RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK E Sbjct: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTD--E 179 Query: 186 GLSAREA-VKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDL 235 + + +K K + + + I + L ++ Sbjct: 180 AIETDDLTIKLVIKALLEVVQSGGK-----NIELAVMRRDQSLKILNPEEI 225 >1IRU-A nrPDB Length = 246 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 4/222 (1%) Query: 3 SIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGT-TSIGIKCNDGVVFAVEKLITSKLLVP 61 G+D ++FSP+GR +QVEYA KA+ G TS+ ++ D V +K + KLL Sbjct: 4 GSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDS 63 Query: 62 QKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQ 121 + + +IGCV +G+ D R V R R EAA++K Y IP+ R+ Q Sbjct: 64 STVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQ 123 Query: 122 AHTLYNSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLV 180 +T +RP G I G+D+ G +Y +P+G Y G+K A G + + + LEK V Sbjct: 124 VYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKV 183 Query: 181 DHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLS 222 + + V+ A + K E+E+ ++ Sbjct: 184 KKKF-DWTFEQTVETAITCLSTVL-SIDFKPSEIEVGVVTVE 223 >5FMG-D nrPDB Length = 241 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 124/250 (49%), Gaps = 11/250 (4%) Query: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 YD + +VFSPDG QVE+A++AV+ G ++ IK ++ V AVEK KL P+ K Sbjct: 2 SYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEK 61 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 + +D H ++GL D R LVN+ R E + P P+ A + + Q T Sbjct: 62 LIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHR 121 Query: 127 NSVRPFGVSTIFGGVDKNG-AHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 VRPFG++T+ G N +Y EPSG Y +K A GK + + LEK ++ E Sbjct: 122 GGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEK---NYQE 178 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 245 + ++ + A K I+ E + + +E++ + + F++ + ++ + Sbjct: 179 NMEQKDCIFLALKAIFEVVELSSKN---VEVALLTEKDLT----FIEEQEINSMVELIDQ 231 Query: 246 EINGDDDEDE 255 E +++++E Sbjct: 232 ERTKNNEQNE 241 >5T0I-L nrPDB Length = 268 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 111/257 (43%), Gaps = 13/257 (5%) Query: 5 GTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN 64 YD +V+SP GR Q+EYA++AV+ G+ ++G+K V K S+L QK Sbjct: 8 RNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQK- 66 Query: 65 VKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHT 124 KI VD HIG +GL D R L N R+E + ++ P+P+ +G Q T Sbjct: 67 -KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 125 Query: 125 LYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP 184 RP+GV + G D G H++ PS +Y+ + + G QSA+ LE+ + Sbjct: 126 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 185 Query: 185 EGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVK------GDLLQE 238 E + E VK + + + +L S+ +F L+ Sbjct: 186 E-CNLNELVKHGLRALRETL----PAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEG 240 Query: 239 AIDFAQKEINGDDDEDE 255 + Q++ DE Sbjct: 241 LEERPQRKAQPAQPADE 257 >6J30-C nrPDB Length = 258 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 68/212 (32%), Positives = 112/212 (52%), Gaps = 5/212 (2%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN-VK 66 YD ++FSP+GR +QVEYA++++ + T+IGI +DG+V A E+ +TS LL + K Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 + ++ I +GL D L+N R A ++ K Y IP+ RL Q +T + Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 127 NSVRPFGVSTIFGGV-DKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 +RPFGVS I+ G D+ G LY PSG+Y G+K + G +A+ L+ + + Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMD---YKD 182 Query: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEIS 217 + +A++ A K + + + LE + Sbjct: 183 DMKVDDAIELALKTLSKTTDSSALTYDRLEFA 214 >4FZC-A nrPDB Length = 250 Score = 236 bits (602), Expect = 9e-63, Method: Composition-based stats. Identities = 77/201 (38%), Positives = 113/201 (56%), Gaps = 5/201 (2%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 Y S + FSP G+ Q++YA+ AV+ G TS+GIK +GVV A EK +S L + + K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEA-ASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 ++ IG VYSG+ PD R LV++ R+ A S+K++Y P + + +Q T Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124 Query: 127 NSVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 VRPFGVS + G D+ NG LY ++PSGSY+ +K A GKG +AK LEK + Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEK---RWND 181 Query: 186 GLSAREAVKQAAKIIYLAHED 206 L +A+ A + + E Sbjct: 182 ELELEDAIHIALLTLKESVEG 202 >3NZW-E nrPDB Length = 234 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 67/217 (30%), Positives = 99/217 (45%), Gaps = 3/217 (1%) Query: 5 GTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN 64 YD FSP GR FQVEYA++A++ G+ ++G++ N V K +L QK Sbjct: 3 RNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQK- 61 Query: 65 VKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHT 124 KI D H+G +GL PD R L N R++ ++ + + L Q +T Sbjct: 62 -KIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNT 120 Query: 125 LYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP 184 RP+GV + G DK+GAHL +PSG+ G A G Q AK LE+ +D Sbjct: 121 QSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFI 180 Query: 185 E-GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCS 220 + + E +K + I + D L I+ Sbjct: 181 KIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVG 217 >5FMG-A nrPDB Length = 260 Score = 209 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 112/256 (43%), Gaps = 17/256 (6%) Query: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVEN-GTTSIGIKCNDGVVFAVEKL------ITSKL 58 + YD ++FSPDG +Q+EYA+KAV+N TS+G+K + V +K KL Sbjct: 7 SMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKL 66 Query: 59 LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQ 118 L I + IGC G+ D +V + R EA+ F + + Sbjct: 67 LDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICD 126 Query: 119 YVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE 177 +Q +T + +R S + G+D+ N L+ +PSG GY+ G Q + + LE Sbjct: 127 KIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLE 186 Query: 178 KLVDHHPEGL---SAREAVK----QAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKF 230 +L++ + + + E ++ A + + K E+E++ S ++ + Sbjct: 187 RLLEKRKKKIQQETIDEDIRNTTILAIEALQTIL-AFDLKASEIEVAIVS-TKNRNFTQI 244 Query: 231 VKGDLLQEAIDFAQKE 246 + ++ A+++ Sbjct: 245 SEKEIDNYLTYIAERD 260 >5L5W-G nrPDB Length = 252 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 71/223 (31%), Positives = 103/223 (46%), Gaps = 7/223 (3%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAV-ENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 YD ++FSP+GR +QVEYA KA + S+ ++ D V +K + KLL P Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 I + R IG V +G IPD R+ R + EAA F+ Y +P A R+ Q +T Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 127 NSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH--- 182 +RP GV F VD+ G +Y +P+G Y GYK ATG +Q LE Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKI 191 Query: 183 -HPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSET 224 H S + V+ A + A + +LE+ + + Sbjct: 192 DHINEESWEKVVEFAITHMIDAL-GTEFSKNDLEVGVATKDKF 233 >6EPF-2 nrPDB Length = 277 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 9/203 (4%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 KA + GTT G+ DG+V + T ++V KN KI + +I C +G D Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTD- 96 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 + + L +P A+R+ L+ G + + GGVD G H Sbjct: 97 MTTQLISSNLELHSLTTGRLPRVVTANRM----LKQMLFRYQGYIGAALVLGGVDVTGPH 152 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 207 LY + P GS G G +A A E D + EA K ++ I ++ Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFE---DKFRPDMEEEEAKKLVSEAIAAGIFND 209 Query: 208 KEKDFELEISWCSLSETNGLHKF 230 +++ S S+ + L + Sbjct: 210 LGSGSNIDLCVISKSKLDFLRPY 232 >5FMG-I nrPDB Length = 229 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 47/236 (19%), Positives = 86/236 (36%), Gaps = 27/236 (11%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ C + V+ + T +V KN K+ + ++I C +G+ D H + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + T + RL Q + + Y + + GGVD NG LY + P Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKV-----CAIVLGGVDVNGPQLYGIHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE 213 GS A G G +A A LE + + ++ E + I ++ Sbjct: 116 HGSSCLLPFTALGSGSLNAMAVLEA---KYRDNMTIEEGKNLVCEAICAGIFNDLGSGGN 172 Query: 214 LEISWCSLSETNGLHKFVK------------------GDLLQEAIDFAQKEINGDD 251 ++I + + + + +L E I++ +K I+ +D Sbjct: 173 VDICVITKDSYQHIRPYKEPNMRLYHLPHPTIYPKGTTPILSEKIEYIKKFISVED 228 >3UNH-H nrPDB Length = 234 Score = 165 bits (419), Expect = 2e-41, Method: Composition-based stats. Identities = 46/169 (27%), Positives = 66/169 (39%), Gaps = 9/169 (5%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D + R Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTE-MTTRMA 59 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 L P A R+ TL+ G S + GGVD NG LY + P Sbjct: 60 ASKMELHALSTGREPRVATVTRI----LRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYL 202 GSY A G G+ +A A LE D ++ A + + I Sbjct: 116 HGSYSRLPFTALGSGQGAAVALLE---DRFQPNMTLEAAQELLVEAITA 161 >5L4G-8 nrPDB Length = 277 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 6/172 (3%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 K + GTT G+ DG+V + T ++V KN KI + +I C +G D Sbjct: 38 KVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTD- 96 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 + + L +P A+R+ L+ G + + GGVD G H Sbjct: 97 MTTQLISSNLELHSLSTGRLPRVVTANRM----LKQMLFRYQGYIGAALVLGGVDVTGPH 152 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKI 199 LY + P GS G G +A A E E A+ V +A Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAA 204 >6AVO-B nrPDB Length = 234 Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats. Identities = 45/169 (26%), Positives = 64/169 (37%), Gaps = 9/169 (5%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D + R Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAE-MTTRMV 59 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 L P A R+ TL+ G S I GGVD G LY + P Sbjct: 60 ASKMELHALSTGREPRVATVTRI----LRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYL 202 GSY A G G+ +A A LE D ++ A + + Sbjct: 116 HGSYSRLPFTALGSGQDAALAVLE---DRFQPNMTLEAAQGLLVEAVTA 161 >3H4P-a nrPDB Length = 219 Score = 163 bits (413), Expect = 7e-41, Method: Composition-based stats. Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 10/206 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQK-NVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHLYMLE 152 EA +K IP A A L + + ++ PF I GG D GA L+ L+ Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKLFSLD 117 Query: 153 PSGSYWGYK-GAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKD 211 P G K ATG G A LE D +S E +K A + A E + Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDR---DMSVEEGIKLALNALKSAMERDTFSG 174 Query: 212 FELEISWCSLSETNGLHKFVKGDLLQ 237 + ++ + +L Sbjct: 175 NGISLAVITKDGVKIFEDEEIEKILD 200 >5FGI-H nrPDB Length = 244 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 49/244 (20%), Positives = 87/244 (35%), Gaps = 9/244 (3%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRH 87 KA G T +G+K N+GVV A + T +V KN K+ + I C +G D Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 66 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 + + + + L+ G I GVD G+H Sbjct: 67 VTQLIGSNIELHSLYTSREPRVVS-----ALQMLKQHLFKYQGHIGAYLIVAGVDPTGSH 121 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 207 L+ + GS + G G +A A LE H + L+ EA+K A+ I ++ Sbjct: 122 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLE---SHWKQDLTKEEAIKLASDAIQAGIWND 178 Query: 208 KEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEINGDDDEDEDDSDNVMSSDDE 267 +++ + + + ++E + K G ++ N+ +E Sbjct: 179 LGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 238 Query: 268 NAPV 271 + Sbjct: 239 QVDI 242 >3IPM-H nrPDB Length = 217 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 45/193 (23%), Positives = 87/193 (45%), Gaps = 9/193 (4%) Query: 29 KAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN-VKIQVVDRHIGCVYSGLIPDGRH 87 + +E GTT++GI D V+ A E+ +T + + KN K+ +D + G +GL+ D + Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 88 LVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 LV + E ++ + +PI A A L + + P+ V + GG+D H Sbjct: 63 LVRYMKAELELYRLQRRVNMPIEAVATLLSNML---NQVKYM-PYMVQLLVGGID-TAPH 117 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 207 ++ ++ +G A+TG G LE + E ++ E V + I A + + Sbjct: 118 VFSIDAAGGSVEDIYASTGSGSPFVYGVLE---SQYSEKMTVDEGVDLVIRAISAAKQRD 174 Query: 208 KEKDFELEISWCS 220 ++++ + Sbjct: 175 SASGGMIDVAVIT 187 >6HEC-1 nrPDB Length = 202 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 49/206 (23%), Positives = 85/206 (41%), Gaps = 9/206 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKN-VKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++G+ C DGVV A EK T + K KI + + +G + D + L + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 EA ++ + + A A + ++ + P+ V + GG+D G +Y ++P Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGKSIYSIDP 116 Query: 154 SGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDF 212 G K ATG G +A LE D + EAV+ A + IY A + + Sbjct: 117 IGGAIEEKDIVATGSGSLTAYGVLE---DRFTPEIGVDEAVELAVRAIYSAMKRDSASGD 173 Query: 213 ELEISWCSLSETNGLHKFVKGDLLQE 238 +++ + E +L + Sbjct: 174 GIDVVKITEDEFYQYSPEEVEQILAK 199 >6HUB-H nrPDB Length = 234 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 6/166 (3%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DG+V + T ++V KN KI + +I C +G D + + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTD-MTTQLI 59 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 L +P A+R+ L+ G + + GGVD G HLY + P Sbjct: 60 SSNLELHSLSTGRLPRVVTANRM----LKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYP 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKI 199 GS G G +A A E E A+ V +A Sbjct: 116 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAA 161 >6HV7-H nrPDB Length = 226 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 44/234 (18%), Positives = 82/234 (35%), Gaps = 9/234 (3%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT G+ DGV+ + T+ +V K+ KI + I C +G+ D + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + + + L+ G I GVD G+HL+ + Sbjct: 61 SNIELHSLYTSREPRVVS-----ALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHA 115 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE 213 GS + G G +A A LE H + L+ EA+K A+ I ++ Sbjct: 116 HGSTDVGYYLSLGSGSLAAMAVLE---SHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSN 172 Query: 214 LEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEINGDDDEDEDDSDNVMSSDDE 267 +++ + + + ++E + K G ++ N+ +E Sbjct: 173 VDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 226 >6EPF-5 nrPDB Length = 263 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 66/172 (38%), Gaps = 8/172 (4%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 +GTT++ K GV+ A + T+ + Q K+ ++ ++ +G D Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYML 151 + ++ K I + A + L V Y + + T+ G DK G LY + Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVY---QYKGMG-LSMGTMICGWDKRGPGLYYV 173 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 + G+ + G G A +++ + L EA A + IY A Sbjct: 174 DSEGNRISGTAFSVGSGSVYAFGVMDRGYSY---DLQVEEAYDLARRAIYQA 222 >5LN3-5 nrPDB Length = 263 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 8/172 (4%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 +GTT++ K GV+ A + T+ + Q K+ ++ ++ +G D Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYML 151 + ++ K I + A + L V Y + + T+ G DK G LY + Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVY---QYKGMG-LSMGTMICGWDKRGPGLYYV 173 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 + G+ + G G A +++ + L +A A + IY A Sbjct: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSY---DLEVEQAYDLARRAIYQA 222 >5L5A-K nrPDB Length = 211 Score = 98.6 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 75/199 (37%), Gaps = 14/199 (7%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQ-KNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ AV+ ++ + + K+ ++ ++ SG D ++ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVST--IFGGVDKNGAHLYML 151 +E + I + A + L + + R G+S + G DK G LY + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKD 211 + G+ +TG G A L+ ++ LS +A+ + I A + Sbjct: 115 DEHGTRLSGNMFSTGSGNTYAYGVLD---SNYKWDLSVEDALYLGKRSILAAAHRDAYSG 171 Query: 212 FELEISWCSLS--ETNGLH 228 + + + +G H Sbjct: 172 GSVNLYHVTEDGWIYHGNH 190 >5FMG-L nrPDB Length = 211 Score = 97.8 bits (242), Expect = 4e-21, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 67/170 (39%), Gaps = 8/170 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKL-LVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K DG++ AV+ + + Q KI ++++I +G D + Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + ++ I + A + L + + Y I G D G +++ ++ Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLC----CGIILSGYDHTGFNMFYVDD 116 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 SG + G G A + L+ D+ L+ +AV+ A IY A Sbjct: 117 SGKKVEGNLFSCGSGSTYAYSILDSAYDY---NLNLDQAVELARNAIYHA 163 >3UNB-K nrPDB Length = 205 Score = 97.8 bits (242), Expect = 5e-21, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 64/170 (37%), Gaps = 8/170 (4%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ A + T+ + Q K+ ++ ++ +G D Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + ++ K I + A + L V Y + + T+ G DK G LY ++ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVY---QYKGMG-LSMGTMICGWDKRGPGLYYVDS 116 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 G+ + G G A +++ + L EA A + IY A Sbjct: 117 EGNRISGTAFSVGSGSVYAYGVMDRGYSY---DLKVEEAYDLARRAIYQA 163 >5L64-K nrPDB Length = 211 Score = 97.4 bits (241), Expect = 6e-21, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 71/197 (36%), Gaps = 10/197 (5%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ A + T+ + Q K+ ++ ++ +G D Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEP 153 + ++ K I + A + L V Y + + T+ G DK G LY ++ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVY---QYKGMG-LSMGTMICGWDKRGPGLYYVDS 116 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE 213 G+ + G G A L+ ++ LS +A+ + I A + Sbjct: 117 EGNRISGATFSVGSGSVYAYGVLD---SNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS 173 Query: 214 LEISWCSLS--ETNGLH 228 + + + +G H Sbjct: 174 VNLYHVTEDGWIYHGNH 190 >6EPC-1 nrPDB Length = 238 Score = 97.0 bits (240), Expect = 8e-21, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 60/177 (33%), Gaps = 10/177 (5%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 V GTT + ++ + GVV + T+ + + K+ + HI C SG D + + Sbjct: 30 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVA 89 Query: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHL 148 + + P + A + Y I G D G + Sbjct: 90 DAVTYQLGFHSIELNEPPLVHTAASLFKEMC-----YRYREDLMAGIIIAGWDPQEGGQV 144 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 Y + G A G G ++ + EG++ E ++ A + LA E Sbjct: 145 YSVPMGGMMVRQSFAIGGSGSSYIYGYVDAT---YREGMTKDECLQFTANALALAME 198 >3UNF-K nrPDB Length = 204 Score = 96.6 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 13/177 (7%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQ-KNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ AV+ T+ + + K+ ++ ++ SG D ++ Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVST--IFGGVDKNGAHLYML 151 +E + I + A + L + + R G+S + G DK G LY + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII-YLAHEDN 207 + +G+ + +TG G A ++ + + LS EA + I Y H DN Sbjct: 115 DDNGTRLSGQMFSTGSGNTYAYGVMDSG---YRQDLSPEEAYDLGRRAIAYATHRDN 168 >5GJQ-a nrPDB Length = 239 Score = 94.7 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 34/194 (17%), Positives = 65/194 (33%), Gaps = 10/194 (5%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 V GTT + ++ + GVV + T+ + + K+ + I C SG D + + Sbjct: 31 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVA 90 Query: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHL 148 + + P + A + Y I G D G + Sbjct: 91 DAVTYQLGFHSIELNEPPLVHTAASLFKEMC-----YRYREDLMAGIIIAGWDPQEGGQV 145 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNK 208 Y + G A G G ++ + EG++ E ++ A + LA E + Sbjct: 146 YSVPMGGMMVRQSFAIGGSGSSYIYGYVDAT---YREGMTKEECLQFTANALALAMERDG 202 Query: 209 EKDFELEISWCSLS 222 + ++ + S Sbjct: 203 SSGGVIRLAAIAES 216 >6AVO-C nrPDB Length = 204 Score = 94.3 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 13/177 (7%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQ-KNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT++ K GV+ AV+ ++ + + K+ ++ ++ SG D ++ Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVST--IFGGVDKNGAHLYML 151 +E + I + A + L + + R G+S + G DK G LY + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII-YLAHEDN 207 + G+ +TG G A ++ + LS EA + I Y H D+ Sbjct: 115 DEHGTRLSGNMFSTGSGNTYAYGVMDSG---YRPNLSPEEAYDLGRRAIAYATHRDS 168 >3NZW-K nrPDB Length = 287 Score = 92.0 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 72/202 (35%), Gaps = 11/202 (5%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLV 89 + +GTT++ + G++ AV+ T+ V Q K+ ++ + +G D + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 148 + + K I + A + L V + + T+ G K G + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNK 208 Y ++ G+ G G+ A L+ ++ LS +A+ + I A + Sbjct: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLD---SNYKWDLSVEDALYLGKRSILAAAHRDA 244 Query: 209 EKDFELEISWCSLS--ETNGLH 228 + + + +G H Sbjct: 245 YSGGSVNLYHVTEDGWIYHGNH 266 >5LEZ-N nrPDB Length = 205 Score = 89.3 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 63/190 (33%), Gaps = 10/190 (5%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT + ++ + GVV + T+ + + K+ + I C SG D + + + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLE 152 + P + A + Y I G D G +Y + Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMC-----YRYREDLMAGIIIAGWDPQEGGQVYSVP 115 Query: 153 PSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDF 212 G A G G ++ + EG++ E ++ A + LA E + Sbjct: 116 MGGMMVRQSFAIGGSGSSYIYGYVDAT---YREGMTKEECLQFTANALALAMERDGSSGG 172 Query: 213 ELEISWCSLS 222 + ++ + S Sbjct: 173 VIRLAAIAES 182 >5CZ8-K nrPDB Length = 221 Score = 88.9 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 73/202 (36%), Gaps = 11/202 (5%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK-IQVVDRHIGCVYSGLIPDGRHLV 89 + +GTT++ + G++ AV+ T+ V + VK + ++ + +G D + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 148 + + K I + A + L V + + T+ G K G + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 121 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNK 208 Y ++ G+ G G+ A L+ ++ LS +A+ + I A + Sbjct: 122 YYVDSDGTRLKGDIFCVGSGQTFAYGVLD---SNYKWDLSVEDALYLGKRSILAAAHRDA 178 Query: 209 EKDFELEISWCSLS--ETNGLH 228 + + + +G H Sbjct: 179 YSGGSVNLYHVTEDGWIYHGNH 200 >5FGE-J nrPDB Length = 198 Score = 87.8 bits (216), Expect = 6e-18, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 63/180 (35%), Gaps = 9/180 (5%) Query: 37 SIGIKCNDGVVFAVEKLITSKLLV-PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREE 95 +GI+ D V+ A K +T + V + K + + H ++G D + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 96 AASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD--KNGAHLYMLEP 153 + + A + + Q + S RP+ V+ + GG D KN LY ++ Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKS--IRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE 213 G+ A G L H+ ++ E + K+ E DF+ Sbjct: 122 LGTKVELPYGAHG--YSGFYTF-SLLDHHYRPDMTTEEGLDL-LKLCVQELEKRMPMDFK 177 >3WXR-K nrPDB Length = 238 Score = 87.4 bits (215), Expect = 7e-18, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 63/180 (35%), Gaps = 9/180 (5%) Query: 37 SIGIKCNDGVVFAVEKLITSKLLV-PQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREE 95 +GI+ D V+ A K +T + V + K + + H ++G D + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 96 AASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD--KNGAHLYMLEP 153 + + A + + Q + S RP+ V+ + GG D KN LY ++ Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKS--IRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 154 SGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFE 213 G+ A G L H+ ++ E + K+ E DF+ Sbjct: 122 LGTKVELPYGAHG--YSGFYTF-SLLDHHYRPDMTTEEGLDL-LKLCVQELEKRMPMDFK 177 >5MPC-h nrPDB Length = 215 Score = 86.2 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 36/177 (20%), Positives = 59/177 (33%), Gaps = 11/177 (6%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 V GT+ + + DGV+ + T+ + + K+ V I C SG D + + Sbjct: 16 VSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIA 75 Query: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGV-DKNGAHL 148 + + + Y TP + V Y + I G DKN + Sbjct: 76 DIVQYHLELYTSQYGTP------STETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEV 129 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 Y + GS A G G +K + E +S E V + A + Sbjct: 130 YTIPLGGSVHKLPYAIAGSGSTFIYGYCDK---NFRENMSKEETVDFIKHSLSQAIK 183 >3NZW-L nrPDB Length = 241 Score = 85.8 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 53/245 (21%), Positives = 84/245 (34%), Gaps = 43/245 (17%) Query: 1 MTSIGTGYDLSNSV------FSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLI 54 M +I + Y S F+P G +NG T +GI D V A + Sbjct: 1 MATIASEYSSEASNTPIEHQFNPYG------------DNGGTILGIAGEDFAVLAGDTRN 48 Query: 55 -TSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKT-PIPIPAF 112 T + + K+ +I +G DG LV R + + + + I + Sbjct: 49 ITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSA 108 Query: 113 ADRLGQYVQAHTLYNSVR--PFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGR 169 A + L R P+ V TI G+D++G +Y +P GSY + A G Sbjct: 109 ARNI------QHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAA 162 Query: 170 QSAKAELEKLVDHHP--------------EGLSAREAVKQAAKIIYLAHEDNKEKDFELE 215 L+ V+ + LS E +K A E + + LE Sbjct: 163 SLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLE 222 Query: 216 ISWCS 220 I + Sbjct: 223 ILIVT 227 >5FMG-M nrPDB Length = 240 Score = 80.5 bits (197), Expect = 9e-16, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 72/194 (37%), Gaps = 13/194 (6%) Query: 19 GRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCV 77 GR F+ Y ++NG T IG+ D V+ A + ++ + + KI + Sbjct: 24 GRGFKRWYPY--IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIG 81 Query: 78 YSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTI 137 SG+ D + L + +++ F + I A L + + + P+ I Sbjct: 82 SSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFF----PYYAFNI 137 Query: 138 FGGVDKNGAH-LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE-----GLSARE 191 GVD+N LY + GSY + G G Q L+ V+ + + + Sbjct: 138 LAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGD 197 Query: 192 AVKQAAKIIYLAHE 205 + I A E Sbjct: 198 DINFVKDAITSATE 211 >6AVO-A nrPDB Length = 199 Score = 78.1 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 71/206 (34%), Gaps = 13/206 (6%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT + ++ + GVV + +++ V + K+ + I C SG D + + + Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLE 152 + + P + A A+ + Y + G D+ G +Y Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNIS-----YKYREDLSAHLMVAGWDQREGGQVYGTL 115 Query: 153 PSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDF 212 G A G G ++ + G+S E + I LA +++ Sbjct: 116 -GGMLTRQPFAIGGSGSTFIYGYVDAA---YKPGMSPEECRRFTTDAIALAM--SRDGSS 169 Query: 213 ELEISWCSLSETNGLHKFVKGDLLQE 238 I +++ H+ + G+ L + Sbjct: 170 GGVIYLVTITAAGVDHRVILGNELPK 195 >1Q5R-H nrPDB Length = 294 Score = 77.0 bits (188), Expect = 8e-15, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 73/183 (39%), Gaps = 13/183 (7%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQK-NVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 +GTT + + GV+ A ++ T L+ + + V D + +G LV Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN------G 145 E ++K+ P+ A+RL V+ L +++ V + G D + Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRG-NLGAAMQGLAVVPLLVGYDLDADDESRA 182 Query: 146 AHLYMLEPSGSYWGYKG--AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 + + G + + A G G AK+ L+K+ + + A++ A + +Y A Sbjct: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEET---ALRAAIESLYDA 239 Query: 204 HED 206 +D Sbjct: 240 ADD 242 >5FMG-K nrPDB Length = 195 Score = 76.2 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 41/186 (22%), Positives = 75/186 (40%), Gaps = 13/186 (6%) Query: 36 TSIGIKCNDGVVFAVEKLITSKLL--VPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 T IG++ N+ VV A + + ++ N K + + + G I D R Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHLYMLE 152 + ++ T + + +FA + + + N PF V+ + G D K+G LY + Sbjct: 63 KNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRN---PFEVNCLIAGYDKKDGYQLYWCD 119 Query: 153 PSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDF 212 + A G G A L+K ++ E L+ EA I L E+ K++ Sbjct: 120 YLSNMDSVNKGAHGYGAYLVSAILDK---YYHENLTVDEA----LDIFKLCFEELKKRFL 172 Query: 213 ELEISW 218 +I++ Sbjct: 173 LTQINY 178 >3UNF-N nrPDB Length = 199 Score = 76.2 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 71/206 (34%), Gaps = 13/206 (6%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT + ++ + GVV + +++ V + K+ + + I C SG D + + + Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYMLE 152 + + P + A A+ + Y I G D+ G +Y Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNIS-----YKYREDLLAHLIVAGWDQREGGQVYGTM 115 Query: 153 PSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDF 212 G G G ++ + G++ E + I LA N++ Sbjct: 116 -GGMLIRQPFTIGGSGSSYIYGYVDAA---YKPGMTPEECRRFTTNAITLAM--NRDGSS 169 Query: 213 ELEISWCSLSETNGLHKFVKGDLLQE 238 I +++ H+ + GD L + Sbjct: 170 GGVIYLVTITAAGVDHRVILGDELPK 195 >1Q5Q-H nrPDB Length = 235 Score = 76.2 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 13/181 (7%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQK-NVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT + + GV+ A ++ T L+ + K+ V D + +G LV Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN------GAH 147 E ++K+ P+ A+RL V+ L +++ V + G D + Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRG-NLGAAMQGLAVVPLLVGYDLDADDESRAGR 119 Query: 148 LYMLEPSGSYWGYKG--AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 + + G + + A G G AK+ L+K+ + + A++ A + +Y A + Sbjct: 120 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEET---ALRAAIESLYDAAD 176 Query: 206 D 206 D Sbjct: 177 D 177 >5L4G-U nrPDB Length = 241 Score = 75.8 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 65/200 (32%), Gaps = 16/200 (8%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNR 91 NG T + I D + A + ++ + ++ K + SG D L Sbjct: 36 NGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 95 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVR--PFGVSTIFGGVDKNGA-HL 148 +K + A A L T+ S R P+ V I GG+D+ G + Sbjct: 96 IEARLKMYKHSNNKAMTTGAIAAMLS------TILYSRRFFPYYVYNIIGGLDEEGKGAV 149 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH------PEGLSAREAVKQAAKIIYL 202 Y +P GSY A G + L+ V LS A++ + Sbjct: 150 YSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS 209 Query: 203 AHEDNKEKDFELEISWCSLS 222 A E + L I + Sbjct: 210 AAERDVYTGDALRICIVTKE 229 >5VFT-S nrPDB Length = 213 Score = 75.4 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 65/200 (32%), Gaps = 16/200 (8%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNR 91 NG T + I D + A + ++ + ++ K + SG D L Sbjct: 8 NGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 67 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVR--PFGVSTIFGGVDKNGA-HL 148 +K + A A L T+ S R P+ V I GG+D+ G + Sbjct: 68 IEARLKMYKHSNNKAMTTGAIAAMLS------TILYSRRFFPYYVYNIIGGLDEEGKGAV 121 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH------PEGLSAREAVKQAAKIIYL 202 Y +P GSY A G + L+ V LS A++ + Sbjct: 122 YSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS 181 Query: 203 AHEDNKEKDFELEISWCSLS 222 A E + L I + Sbjct: 182 AAERDVYTGDALRICIVTKE 201 >6EPF-6 nrPDB Length = 240 Score = 74.3 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 46/228 (20%), Positives = 74/228 (32%), Gaps = 30/228 (13%) Query: 15 FSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRH 73 FSP YA NG T + I D + A + ++ + ++ K + Sbjct: 29 FSP--------YAF----NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDK 76 Query: 74 IGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVR--P 131 SG D L +K + A A L T+ S R P Sbjct: 77 TVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLS------TILYSRRFFP 130 Query: 132 FGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHH------P 184 + V I G+D+ G +Y +P GSY A G + L+ V Sbjct: 131 YYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEH 190 Query: 185 EGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVK 232 L+ A++ + A E + L I C +++ + V Sbjct: 191 VPLTLDRAMRLVKDVFISAAERDVYTGDALRI--CIVTKEGIREETVP 236 >5FMG-H nrPDB Length = 252 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 40/247 (16%), Positives = 78/247 (31%), Gaps = 60/247 (24%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQK-NVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 TT IGI ++GV+ A + +S + K + KI ++ ++ SG + ++ + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 94 EEAASFK------------------KLYKTPIPIPA------------------------ 111 S K Y I I + Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 112 -------FADRLGQYVQA--HTLYNSVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWG-Y 160 + + + +T N + IFGG DK LY + +GS + Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNF---LSCALIFGGYDKIKKQQLYAVNLNGSIIEKH 177 Query: 161 KGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCS 220 A +G G ++ L+ D + + ++ +E + A ++ + I + Sbjct: 178 DFAVSGSGSIYIQSYLQ---DKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNIT 234 Query: 221 LSETNGL 227 S Sbjct: 235 KSFVEEF 241 >2JAY-A nrPDB Length = 291 Score = 64.3 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 65/182 (35%), Gaps = 11/182 (6%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 +GTT + +K GVV A ++ T ++ + K+ + D + +G Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARL 115 Query: 92 GREEAASFKKLYKTPIP----IPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGA- 146 E ++KL P+ I A + + A P D A Sbjct: 116 YAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 175 Query: 147 HLYMLEPSGSYW--GYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAH 204 + + +G + A G G AK+ ++KL +G ++ A + +Y A Sbjct: 176 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDG---DSGLRVAVEALYDAA 232 Query: 205 ED 206 +D Sbjct: 233 DD 234 >5LF3-J nrPDB Length = 201 Score = 61.2 bits (147), Expect = 5e-10, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 66/171 (38%), Gaps = 15/171 (8%) Query: 38 IGIKCNDGVVFAVEKLITSKLL-VPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEA 96 IGI+ D V+ A +++ S ++ + + K+ + I + G D ++ Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 97 ASFKKLYKTPIPIPAFA----DRLGQYVQAHTLYNSVRPFGVSTIFGGVDK-NGAHLYML 151 +K + A A L +++ T P+ V+ + G D+ G LY + Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCLRSRT------PYHVNLLLAGYDEHEGPALYYM 118 Query: 152 EPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYL 202 + + AA G G + L++ ++ +S AV+ K + Sbjct: 119 DYLAALAKAPFAAHGYGAFLTLSILDR---YYTPTISRERAVELLRKCLEE 166 >4Y8P-I nrPDB Length = 205 Score = 60.8 bits (146), Expect = 7e-10, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 56/177 (31%), Gaps = 12/177 (6%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLL-VPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 NG + + D V A + + S+ L V K KI H+ +GL D L Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN--GAHLY 149 R + +K + I F + + P+ V + G++ + Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYE----RRFGPYFVGPVVAGINSKSGKPFIA 122 Query: 150 MLEPSGSYWGYK-GAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 + G K +G E L + L + + ++ + A + Sbjct: 123 GFDLIGCIDEAKDFIVSGTASDQLFGMCESL---YEPNLEPEDLFETISQALLNAAD 176 >5FMG-J nrPDB Length = 218 Score = 60.8 bits (146), Expect = 7e-10, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 62/181 (34%), Gaps = 20/181 (11%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLL--VPQKNVKIQVVDRHIGCVYSGLIPDGRHLVN 90 NG +G+ ++ V A + + + V K KI ++ ++ SGL D + L Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 91 RGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGG------VDKN 144 R ++ + + FA+ L + ++ P+ V+ I G VD+ Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFS----PYFVNPIVVGFKLKHYVDEE 123 Query: 145 G-------AHLYMLEPSGSYWGYK-GAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQA 196 G +L + G+ + G + E L + E + Q Sbjct: 124 GEKKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQC 183 Query: 197 A 197 Sbjct: 184 L 184 >5LZP-A nrPDB Length = 242 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 62/180 (34%), Gaps = 11/180 (6%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93 T + +K GVV A ++ T ++ + K+ + D + +G Sbjct: 1 ATIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYA 60 Query: 94 EEAASFKKLYKTPIP----IPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGA-HL 148 E ++KL P+ I A + + A P D A + Sbjct: 61 VELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRI 120 Query: 149 YMLEPSGSYW--GYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHED 206 + +G + A G G AK+ ++KL +G ++ A + +Y A +D Sbjct: 121 VSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDG---DSGLRVAVEALYDAADD 177 >5FMG-N nrPDB Length = 265 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 41/254 (16%), Positives = 82/254 (32%), Gaps = 51/254 (20%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVP-QKNVKIQVVDRHIGCVYSGLIPDGR--- 86 V GT+ I IK G++ A ++ + Q +I ++ +SG + D + Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 87 HLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGA 146 L+ R S KK + + + + + N + P + I G++ Sbjct: 66 ELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRV--FYVRKNRIDPLFNNIIIAGINSQKY 123 Query: 147 H-------LYM-----------------------------LEPSGSYWGYKGAATGKGRQ 170 LY ++ G+ + TG R Sbjct: 124 DNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARY 183 Query: 171 SAKAELEKLVDHHPEGLSAREA---VKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGL 227 A L DH+ + ++ EA + + +I+Y D +F ++I + Sbjct: 184 FALTLL---RDHYKDNMTEEEARILINECLRILY--FRDATSSNF-IQIVKVTSKGVEYE 237 Query: 228 HKFVKGDLLQEAID 241 ++ +L A Sbjct: 238 EPYILPCVLNSADY 251 >3UNE-I nrPDB Length = 205 Score = 57.3 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 22/177 (12%), Positives = 51/177 (28%), Gaps = 11/177 (6%) Query: 33 NGTTSIGIKCNDGVVFAVEKLI-TSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 NG + +K + V A ++ +V KI + + +GL D + + R Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN--GAHLY 149 + ++ I + + P+ + G+D + Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYE----KRFGPYYTEPVIAGLDPKTFKPFIC 122 Query: 150 MLEPSGS-YWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 L+ G +G + E L + + ++ + A + Sbjct: 123 SLDLIGCPMVTDDFVVSGTCSEQMYGMCESL---WEPNMDPEHLFETISQAMLNAVD 176 >6GOP-M nrPDB Length = 246 Score = 54.6 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 38/183 (20%), Positives = 69/183 (37%), Gaps = 14/183 (7%) Query: 31 VENGTTSIGIKCNDGVVFAVEKLITSK-LLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLV 89 + GT+ I +K ++GV+ A + L + LL ++ V + SG I D +H+ Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 90 NRGREEAASFKK-----LYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN 144 ++ + + + L + + + + P + I GV N Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVM--YQRRSKMNPLWNAIIVAGVQSN 135 Query: 145 GAH-LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH--HPEGLSA---REAVKQAAK 198 G L + G + ATG G A L K+VD + EA+ A + Sbjct: 136 GDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMR 195 Query: 199 IIY 201 ++Y Sbjct: 196 VLY 198 >4HO7-A nrPDB Length = 179 Score = 51.2 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 28/188 (14%), Positives = 65/188 (34%), Gaps = 23/188 (12%) Query: 35 TTSIGIKCNDGVVFAVEKLIT--SKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRG 92 TT + ++ D VV ++ +T +++ K++ ++ + ++G D L+ + Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 93 REEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLE 152 + F + + ++R S I ++ ++ Sbjct: 61 ENKIGEF---------PNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEET----LEID 107 Query: 153 PSGSYWGYKG---AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKE 209 G+ + A G G AKA L+D A K A K + +A + + Sbjct: 108 GQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYD-----AEKIARKAMRIATDIDVF 162 Query: 210 KDFELEIS 217 + ++ Sbjct: 163 SNEHWDVE 170 >5LF6-M nrPDB Length = 219 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 71/176 (40%), Gaps = 12/176 (6%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSK-LLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 GT+ +G+K GVV A + L + L + +I V+ SG D ++L Sbjct: 7 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 66 Query: 92 GREEAASFKKLYKT----PIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 + + L P I ++ R ++ + + P + + GG + Sbjct: 67 LGQMVIDEELLGDGHSYSPRAIHSWLTR-----AMYSRRSKMNPLWNTMVIGGYADGESF 121 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP--EGLSAREAVKQAAKIIY 201 L ++ G + ATG G A+ L ++++ P AR+ V++ +++Y Sbjct: 122 LGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLY 177 >5GJQ-g nrPDB Length = 264 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 71/176 (40%), Gaps = 12/176 (6%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSK-LLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 GT+ +G+K GVV A + L + L + +I V+ SG D ++L Sbjct: 52 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111 Query: 92 GREEAASFKKLYKT----PIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAH 147 + + L P I ++ R ++ + + P + + GG + Sbjct: 112 LGQMVIDEELLGDGHSYSPRAIHSWLTR-----AMYSRRSKMNPLWNTMVIGGYADGESF 166 Query: 148 LYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP--EGLSAREAVKQAAKIIY 201 L ++ G + ATG G A+ L ++++ P AR+ V++ +++Y Sbjct: 167 LGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLY 222 >6EPE-7 nrPDB Length = 263 Score = 47.7 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 68/177 (38%), Gaps = 14/177 (7%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSK-LLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNR 91 GT+ +G+K + GVV A + L + L + +I V+ SG D ++L Sbjct: 51 TGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQV 110 Query: 92 GREEAASFKK-----LYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGA 146 + + Y + ++ + + P + + GG + Sbjct: 111 LGQMVIDEELFGDGHSYSPRAIHSWLTRAM------YSRRSKMNPLWNTKVIGGYAGGES 164 Query: 147 HLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP--EGLSAREAVKQAAKIIY 201 L ++ G + ATG G A+ L ++++ P ARE V++ +++Y Sbjct: 165 FLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLY 221 >5NYW-A nrPDB Length = 251 Score = 36.5 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 23/217 (10%), Positives = 72/217 (33%), Gaps = 21/217 (9%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV----DRHIGCVYSGLIPDGRHLVN 90 T + ++ + G+ FA + + + K+ + +R + +G + + +V+ Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAGVDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIVS 60 Query: 91 RGREEA--------ASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGG-V 141 + + +Y+ + + + F + + GG + Sbjct: 61 LLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQI 120 Query: 142 DKNGAHLYMLEPSGSYWG----YKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAA 197 G L+ + P G++ G+ + K +++++ + +A++ A Sbjct: 121 KGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTP---LDQAMQCAL 176 Query: 198 KIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGD 234 + N L++ L + ++ + Sbjct: 177 ISMDSTLRSNLSVGLPLDVMIYPLDSFSTEQQYRITE 213 >6DTT-A nrPDB Length = 383 Score = 36.2 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 13/77 (16%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 YD + FS G+ + V YA++AV I D V + + +L+ K Sbjct: 88 YDTALKAFSYGGKLYGVPYAMEAVAL------IYNKDYVDSVPKTM--DELIEKAK---- 135 Query: 68 QVVDRHIGCVYSGLIPD 84 +D G G I D Sbjct: 136 -QIDEEYGGEVRGFIYD 151 >5LOY-A nrPDB Length = 240 Score = 35.8 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 74/197 (37%), Gaps = 19/197 (9%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV----DRHIGCVYSGLIPDGRHLVN 90 T +GI+ ++G+VFA + + + K+ V +R I + +G + + +++ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 91 RGREEAASFKKLYKTPIPIPAFADRLGQYV------QAHTLYNSVRPFGVSTIFGG-VDK 143 E ++ T + A +G+ + A L F S I GG + Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 144 NGAHLYMLEPSGSYWG----YKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKI 199 L+++ P+G++ G+ + K L++++ S +A K A Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGETKYG-KPILDRVI---TPDTSLEDAAKCALVS 176 Query: 200 IYLAHEDNKEKDFELEI 216 N L++ Sbjct: 177 FDSTMRSNLSVGLPLDL 193 >5JI2-A nrPDB Length = 184 Score = 35.0 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 55/177 (31%), Gaps = 35/177 (19%) Query: 35 TTSIGIKCNDGVVFAVEKLITSKL-LVPQKNVKIQVV-DRHIGCVYSGLIPDGRHLVNRG 92 TT + ++ N VV A + T ++ K++ + + + ++G D L Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTL---- 57 Query: 93 REEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGV-----STIFGGV-DKNGA 146 E K + A + + L V S I G D Sbjct: 58 -FELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQP 116 Query: 147 HLYMLEPSGSYWGYKGAATGKG----RQSAKAELEKLVDHHPEGLSAREAVKQAAKI 199 A G G + +A+A LE LSARE ++A I Sbjct: 117 ------------ENDLIAIGSGGPYAQAAARALLENT------ELSAREIAEKALDI 155 >2FU0-A nrPDB Length = 160 Score = 32.3 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 28/78 (35%), Gaps = 1/78 (1%) Query: 123 HTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELE-KLVD 181 N +PF VS G + NG+ ++ + +K GK Q +K L+ + V Sbjct: 81 FDHLNHSKPFMVSMANCGPNTNGSQFFITTVPCPWLDFKHTVFGKVTQGSKIVLDIEKVR 140 Query: 182 HHPEGLSAREAVKQAAKI 199 + KI Sbjct: 141 TDKRDKPLEDIKILNIKI 158 >2GHB-A nrPDB Length = 382 Score = 31.9 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 16/24 (66%) Query: 8 YDLSNSVFSPDGRNFQVEYAVKAV 31 Y+ + + FS G+ + + YA++A+ Sbjct: 88 YETALNAFSYGGKLYGIPYAMEAI 111 >3QBR-A nrPDB Length = 179 Score = 31.5 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 44/147 (29%), Gaps = 7/147 (4%) Query: 84 DGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGG--- 140 D +L + + I + +G + Q + + + P S Sbjct: 37 DTDYLTDLLDNTNIDLTCVPNGQEIIHSLLQLVGDFNQRFSQTHEIEPVAQSLGIDSDKP 96 Query: 141 VDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII 200 VDK ++ LE + GR A +++ +A++ K Sbjct: 97 VDKTALEIFYLEILNGLFE----KLNWGRIVAMFAFLRILVLRLSKHGHSDAIQMLIKTT 152 Query: 201 YLAHEDNKEKDFELEISWCSLSETNGL 227 ++ + L W L E +G Sbjct: 153 SQYSDEKLKNWINLHDGWSGLIEFSGR 179 >5EKZ-A nrPDB Length = 294 Score = 30.8 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 18/125 (14%), Positives = 41/125 (32%), Gaps = 10/125 (8%) Query: 96 AASFKKLYKTPIPIPAFADRLGQYVQA--HTLYNSVRPFGVSTIFGGVDKNGA--HL--- 148 A + +P L + LY P G S + + +G HL Sbjct: 103 ANILELCRSKNMPKSTIESALKTEKNKGIYLLYEGRGPGGSSLLIEALSNSGPKCHLDIK 162 Query: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNK 208 Y+L +G + +E D + ++ A++ A + ++ + Sbjct: 163 YILNKNGGMMAEGARHFFDKKGVVVVGVE---DREKKAVNLERALELAIEAGAEDVKEAE 219 Query: 209 EKDFE 213 +++ + Sbjct: 220 DEEEK 224 >1XF1-A nrPDB Length = 926 Score = 28.8 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 25/74 (33%), Gaps = 1/74 (1%) Query: 145 GAHLYMLEPSGSYWGYKGAATGKGRQS-AKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 203 G + + Y G + + L+K + ++ E + A K++ + Sbjct: 388 GQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSS 447 Query: 204 HEDNKEKDFELEIS 217 ++D + S Sbjct: 448 ATALYDEDEKAYFS 461 >4W8N-A nrPDB Length = 330 Score = 28.4 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 25/84 (29%), Gaps = 3/84 (3%) Query: 11 SNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV 70 F G EY K + G++ GI + ++ E + L + + Sbjct: 241 DVINFESTGNLIAPEYGFKISKRGSS--GIMKTEKILENCETKCQTPLGAINTTLPFHNI 298 Query: 71 DR-HIGCVYSGLIPDGRHLVNRGR 93 IG + D L R Sbjct: 299 HPLTIGECPKYVKSDRLILATGLR 322 >2RGO-A nrPDB Length = 607 Score = 28.4 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 13/112 (11%) Query: 185 EGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSET----------NGLHKFVKGD 234 ++ + V +I + + ++E SW L G + + Sbjct: 310 PKVTQED-VDYLLDVINHRYPEANITLADIEASWAGLRPLLIGNSGSDYNGGDNGSISDK 368 Query: 235 LLQEAIDFAQ--KEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGD 284 + +D KE E ED +++ +S DE AP + ++ ++E D Sbjct: 369 SFNKVVDTVSEYKENKVSRAEVEDVLNHLENSRDEKAPSTISRGSSLEREPD 420 >3QQE-A nrPDB Length = 327 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 19/62 (30%), Gaps = 2/62 (3%) Query: 11 SNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV 70 F G EY K + G++ GI +G + E + L + V Sbjct: 238 DTINFESTGNLIAPEYGFKISKRGSS--GIMKTEGTLENCETKCQTPLGAINTTLPFHNV 295 Query: 71 DR 72 Sbjct: 296 HP 297 >2WR7-A nrPDB Length = 506 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 19/62 (30%), Gaps = 2/62 (3%) Query: 11 SNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV 70 F G EY K + G++ GI +G + E + L + V Sbjct: 251 DTINFESTGNLIAPEYGFKISKRGSS--GIMKTEGTLENCETKCQTPLGAINTTLPFHNV 308 Query: 71 DR 72 Sbjct: 309 HP 310 >3P1W-A nrPDB Length = 475 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 38 IGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHIGC 76 GIK +DG + +K+I V KI+ + + I C Sbjct: 291 CGIKSSDGEIAYCDKVICDPSYVMHLKNKIKKIGQVIRC 329 >2WR0-A nrPDB Length = 509 Score = 28.1 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 24/84 (28%), Gaps = 3/84 (3%) Query: 11 SNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVV 70 F G EY K + G++ GI + + E + L + + Sbjct: 251 DVINFESTGNLIAPEYGFKISKRGSS--GIMKTEKTLENCETKCQTPLGAINTTLPFHNI 308 Query: 71 DR-HIGCVYSGLIPDGRHLVNRGR 93 IG + D L R Sbjct: 309 HPLTIGECPKYVKSDRLVLATGLR 332 >2BTY-A nrPDB Length = 282 Score = 26.9 bits (58), Expect = 9.9, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 17/42 (40%), Gaps = 2/42 (4%) Query: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHI 74 +G ++GI D + EK + K++ V+ I Sbjct: 113 HGGRAVGICGKDSKLIVAEKETKHGDIGY--VGKVKKVNPEI 152 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.138 0.362 Lambda K H 0.267 0.0425 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,239,381 Number of Sequences: 36641 Number of extensions: 471237 Number of successful extensions: 1892 Number of sequences better than 10.0: 110 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 1423 Number of HSP's gapped (non-prelim): 286 length of query: 288 length of database: 10,336,785 effective HSP length: 96 effective length of query: 192 effective length of database: 6,819,249 effective search space: 1309295808 effective search space used: 1309295808 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 59 (27.3 bits)