BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20711 (480 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3RBF-A nrPDB 1000 0.0 1JS3-A nrPDB 880 0.0 3K40-A nrPDB 609 e-175 4E1O-A nrPDB 553 e-158 6JRL-A nrPDB 503 e-143 6EEI-A nrPDB 484 e-137 6EEM-B nrPDB 409 e-114 6EEW-A nrPDB 408 e-114 6EEQ-A nrPDB 362 e-100 4OBV-D nrPDB 181 5e-46 2OKJ-A nrPDB 144 6e-35 2OKK-A nrPDB 144 1e-34 6ENZ-A nrPDB 139 3e-33 4RIT-B nrPDB 137 7e-33 5O5C-A nrPDB 123 1e-28 2JIS-A nrPDB 122 3e-28 2QMA-A nrPDB 119 3e-27 3F9T-A nrPDB 50 3e-06 5HSI-A nrPDB 37 0.020 1IAY-A nrPDB 35 0.067 3MAF-B nrPDB 33 0.29 4W8I-A nrPDB 32 0.84 4QQ1-A nrPDB 30 1.7 2HIX-A nrPDB 30 2.8 4Q6R-A nrPDB 30 3.1 5HB1-A nrPDB 28 9.2 >3RBF-A nrPDB Length = 480 Score = 1000 bits (2585), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/480 (99%), Positives = 480/480 (100%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 MNASEFRRRGKEMVDY+ANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV Sbjct: 1 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD Sbjct: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM Sbjct: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV Sbjct: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN Sbjct: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL Sbjct: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE Sbjct: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480 >1JS3-A nrPDB Length = 486 Score = 880 bits (2275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/468 (89%), Positives = 448/468 (95%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 MNAS+FRRRGKEMVDYMA+Y+EGIEGRQVYPDV+PGYLRPLIPA APQEPDTFEDI+ DV Sbjct: 1 MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDV 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD Sbjct: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKML+LP+AFL +AGEGGGVIQGSASEATLVALLAARTKV+ RLQAASP LTQ A++ Sbjct: 121 WLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVVRRLQAASPGLTQGAVL 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 EKLVAY+SDQAHSSVERAGLIGGVKLKAIPSDG FAMRASALQEALERDKAAGLIPFF+V Sbjct: 181 EKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTT+CCSFDNLLEVGPIC++EDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN Sbjct: 241 ATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKWLLVNFDCSAMWVK+RTDLTGAF+LDP YLKHSHQ SGLITDYRHWQ+PLGRRFRSL Sbjct: 301 PHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 KMWFVFRMYGVKGLQAYIRKHVQLSHEFE+ V QDPRFE+C EV LGLVCFRLKGS+ +N Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLN 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 EALL+RINSA+KIHLVPC LR +FVLRFAICSR VES HV+ AWEHI+ Sbjct: 421 EALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIR 468 >3K40-A nrPDB Length = 475 Score = 609 bits (1570), Expect = e-175, Method: Compositional matrix adjust. Identities = 290/479 (60%), Positives = 369/479 (77%), Gaps = 4/479 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M A EF+ K MVD++A Y+E I R+V P+V+PGYL+PLIP AAP++P+ ++D++ D+ Sbjct: 1 MEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDI 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 E++IMPGVTHWHSP F AYFPTA+SYPA++ADML GAI CIGF+W ASPACTELE VMMD Sbjct: 61 ERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKMLELP FL G+GGGVIQG+ASE+TLVALL A+ K + ++ PE + I+ Sbjct: 121 WLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTIL 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 KLV Y SDQAHSSVERAGL+GGVKL+++ S+ N MR +AL++A+E+D A GLIPF+ V Sbjct: 181 GKLVGYCSDQAHSSVERAGLLGGVKLRSVQSE-NHRMRGAALEKAIEQDVAEGLIPFYAV 239 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 TLGTT C+FD L E GP+ NK ++W+HVDAAYAGSAFICPE+RHL+ G+E ADSFNFN Sbjct: 240 VTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFN 299 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKW+LVNFDCSAMW+K + + AF +DP YLKH Q S DYRHWQIPLGRRFR+L Sbjct: 300 PHKWMLVNFDCSAMWLKDPSWVVNAFNVDPLYLKHDMQGSA--PDYRHWQIPLGRRFRAL 357 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 K+WFV R+YGV+ LQA+IR+H + +F L D RFE+ E+ +GLVCFRLKGSN+ N Sbjct: 358 KLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCFRLKGSNERN 417 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAER 479 EALL+RIN IHLVP ++D + LR AICSR +S ++ +W+ + AAD + E+ Sbjct: 418 EALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQSEDMEYSWKEVSA-AADEMEQEQ 475 >4E1O-A nrPDB Length = 481 Score = 553 bits (1426), Expect = e-158, Method: Compositional matrix adjust. Identities = 248/476 (52%), Positives = 347/476 (72%), Gaps = 3/476 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M E+R RG+EMVDY+ Y+ + R+V PDV+PGYLR +P +AP++PD+++ I D+ Sbjct: 6 MEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDI 65 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 E+IIMPGV HW SP+ AY+P +S+P++L DML AI C+GF+WA+SPACTELE +MD Sbjct: 66 ERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMD 125 Query: 121 WLGKMLELPKAFLNEK-AGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179 WL KML LP+ FL+ + +GGGV+Q + SE+TL+ALLAAR I ++ + P+ ++++ Sbjct: 126 WLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESSL 185 Query: 180 MEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFM 239 +LVAY+SDQAHSSVE+AGLI VK+K +P D NF++R ALQ+A+E DK GL+P F+ Sbjct: 186 NARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFV 245 Query: 240 VATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNF 299 ATLGTT C+FD L E+GPIC +E +WLH+DAAYAG+AF+CPEFR L G+E+ADSF F Sbjct: 246 CATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTF 305 Query: 300 NPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRS 359 NP KW++V+FDC+ WVK + L F ++P YL+H+ +SG+ TD+ HWQIPL RRFRS Sbjct: 306 NPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHA--NSGVATDFMHWQIPLSRRFRS 363 Query: 360 LKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKV 419 +K+WFV R +GVK LQA++R +++ FESLVR DP FEI + LGLV FRLKG N + Sbjct: 364 VKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNSL 423 Query: 420 NEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVL 475 E +L+ I A ++ L+P ++DK ++RF + S+ + R W I++ A +L Sbjct: 424 TENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLIL 479 >6JRL-A nrPDB Length = 510 Score = 503 bits (1295), Expect = e-143, Method: Compositional matrix adjust. Identities = 228/479 (47%), Positives = 327/479 (68%), Gaps = 1/479 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M+A EFR GK +DY+A+Y+E I V P+VEPGYL L+P P+EP+ ++D++ D+ Sbjct: 1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDI 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 ++I PG+THW SP+ AY+PT++SYP+++ +ML G IGFSW SPACTELE V+MD Sbjct: 61 SRVIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WL K L+LP F + G GGGVIQGSASEA LVA+LAAR + + + + PEL+++ + Sbjct: 121 WLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVR 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 +LVAYSSDQ++S +E+AG++ + ++ +P+ +F +R L+ A+E D AAG IP V Sbjct: 181 GRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTT C++D++ + +C + +WLHVDAAYAG AF E L G++ DS NFN Sbjct: 241 ATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 HK++LVNFDCSAMW++ + +F +D YLKH H+ I D+RHWQIPLGRRFR+L Sbjct: 301 LHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRAL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 K+W FR G +GL+ ++RKH++L+ +FE LV +D RFE+ LGLVCFR KG N++ Sbjct: 361 KVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCFRPKGDNEIT 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAER 479 LLQR+ KKI++V + LRF +C +++ + AW+ I+ D L+AE+ Sbjct: 421 TQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMDTKASDIDFAWQEIESQLTD-LQAEQ 478 >6EEI-A nrPDB Length = 490 Score = 484 bits (1246), Expect = e-137, Method: Compositional matrix adjust. Identities = 236/487 (48%), Positives = 316/487 (64%), Gaps = 22/487 (4%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M++ + R G MVD++A+Y + IE V V+PGYL L+P +AP P+T + +++DV Sbjct: 12 MDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDSAPDHPETLDQVLDDV 71 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 I+PGVTHW SP FFAY+P+ SS L +ML +G +GFSW SPA TELE +++D Sbjct: 72 RAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPAATELEMIVLD 131 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 W+ K+L LP+ F+++ G GGGVIQGSASEA LV L+AAR KV+ + + + Sbjct: 132 WVAKLLNLPEQFMSK--GNGGGVIQGSASEAVLVVLIAARDKVLRSVGKNA--------L 181 Query: 181 EKLVAYSSDQAHSSVERAGLIGGV-----KLKAIPSDGNFAMRASALQEALERDKAAGLI 235 EKLV YSSDQ HS++++A I G+ ++ S N+A+R +LQEA+ RD AGLI Sbjct: 182 EKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLI 241 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PFF+ A +GTT+ + D L +G I N IW HVDAAYAGSA ICPE+R ++GVE AD Sbjct: 242 PFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETAD 301 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 SFN N HKW L NFDCS +WVK + LT A +P +LK+ + L+ DY+ WQIPLGR Sbjct: 302 SFNMNAHKWFLTNFDCSLLWVKDQDSLTLALSTNPEFLKNKASQANLVVDYKDWQIPLGR 361 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRL-- 413 RFRSLK+W V R+YG + L++YIR H++L+ EFE LV QDP FEI I LVCFRL Sbjct: 362 RFRSLKLWMVLRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVP 421 Query: 414 -----KGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 K N N LL +NS+ K+ + L K VLR AI + E HV+ AW+ I+ Sbjct: 422 VKDEEKKCNNRNRELLDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQ 481 Query: 469 ELAADVL 475 E A+ +L Sbjct: 482 EEASYLL 488 >6EEM-B nrPDB Length = 512 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 204/504 (40%), Positives = 307/504 (60%), Gaps = 38/504 (7%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 ++ EFRR+G ++D++A+Y + +E V VEPGYL+ +P +AP P++ E I+ DV Sbjct: 20 LDPDEFRRQGHMIIDFLADYYKNVEKYPVRSQVEPGYLKKRLPESAPYNPESIETILEDV 79 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 I+PG+THW SP +FAYFP++ S L +ML +GF+W +SPA TELE+++M+ Sbjct: 80 TNDIIPGLTHWQSPNYFAYFPSSGSIAGFLGEMLSTGFNVVGFNWMSSPAATELESIVMN 139 Query: 121 WLGKMLELPKAFL--NEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAA 178 WLG+ML LPK+FL ++ + GGGV+QG+ EA L L AAR K+++++ + Sbjct: 140 WLGQMLTLPKSFLFSSDGSSGGGGVLQGTTCEAILCTLTAARDKMLNKIGREN------- 192 Query: 179 IMEKLVAYSSDQAHSSVERAGLIGGVK---LKAIPSD--GNFAMRASALQEALERDKAAG 233 + KLV Y+SDQ H ++++A I G+ ++AI + NF + ++LQ A+ D +G Sbjct: 193 -INKLVVYASDQTHCALQKAAQIAGINPKNVRAIKTSKATNFGLSPNSLQSAILADIESG 251 Query: 234 LIPFFMVATLGTTTCCSFDNLLEVGPICNKED---IWLHVDAAYAGSAFICPEFRHLLNG 290 L+P F+ AT+GTT+ + D +GP+C IW+H+DAAYAGSA ICPEFRH ++G Sbjct: 252 LVPLFLCATVGTTSSTAVD---PIGPLCAVAKLYGIWVHIDAAYAGSACICPEFRHFIDG 308 Query: 291 VEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQ 350 VE ADSF+ N HKW DC +WVK L A P YLK+ +S + DY+ WQ Sbjct: 309 VEDADSFSLNAHKWFFTTLDCCCLWVKDSDSLVKALSTSPEYLKNKATESKQVIDYKDWQ 368 Query: 351 IPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVC 410 I L RRFRS+K+W V R YGV L+ ++R HV+++ F+ L+ D RFEI V +VC Sbjct: 369 IALSRRFRSMKLWLVLRSYGVANLRTFLRSHVKMAKHFQGLIGMDNRFEIVVPRTFAMVC 428 Query: 411 FRLK-----------------GSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSR 453 FRLK +N+VN LL+ +N++ KI++ + +++RFA+ + Sbjct: 429 FRLKPTAIFKQKIVDNDYIEDQTNEVNVKLLESVNASGKIYMTHAVVGGVYMIRFAVGAT 488 Query: 454 TVESAHVQRAWEHIKELAADVLRA 477 E HV AW+ ++E +L A Sbjct: 489 LTEERHVTGAWKVVQEHTDAILGA 512 >6EEW-A nrPDB Length = 500 Score = 408 bits (1049), Expect = e-114, Method: Compositional matrix adjust. Identities = 206/487 (42%), Positives = 304/487 (62%), Gaps = 21/487 (4%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 + A EFR++ MVD++A+Y + +E V +VEPGYLR IP AP P+ +DI+ D+ Sbjct: 22 LEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDI 81 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 +K I+PG+T+W SP F+A+FP S A L +ML A+ +GF+W +SPA TELE ++MD Sbjct: 82 QKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMD 141 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WL ++L+LPK+F+ +G GGGVIQ + SE+ L ++AAR + + +L S + Sbjct: 142 WLAQILKLPKSFMF--SGTGGGVIQNTTSESILCTIIAARERALEKLGPDS--------I 191 Query: 181 EKLVAYSSDQAHSSVERAGLIGGV---KLKAIPS--DGNFAMRASALQEALERDKAAGLI 235 KLV Y SDQ H+ + + G+ ++ IP+ + +F + L++ +E D AAG + Sbjct: 192 GKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYV 251 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 P F+ ATLGTT+ + D + + I N+ IW+HVDAAYAGSA ICPEFRH L+G+E D Sbjct: 252 PLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVD 311 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 S + +PHKWLL DC+ +WVK+ L A +P YLK+ D + D+++WQI GR Sbjct: 312 SLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGR 371 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 +FRSLK+W + R YGV LQ++IR V ++ FE VR D RFEI V LVCFRLK Sbjct: 372 KFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKP 431 Query: 416 S------NKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKE 469 +VN+ LL +NS ++++ + ++LR A+ S E HV+R W+ I++ Sbjct: 432 DVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQK 491 Query: 470 LAADVLR 476 L D+L+ Sbjct: 492 LTDDLLK 498 >6EEQ-A nrPDB Length = 490 Score = 362 bits (928), Expect = e-100, Method: Compositional matrix adjust. Identities = 187/487 (38%), Positives = 276/487 (56%), Gaps = 26/487 (5%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M+ +E K +VD++ Y + +E R V P V+PG+L +P AP ++ E I++DV Sbjct: 17 MDLTELSTESKLVVDFITQYYQTLETRPVQPRVKPGFLTGQLPDKAPFHGESMEVILSDV 76 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 + I+PG+THW SP F AYFP +SS +L ++LC + IGF+W++SPA TELE V++D Sbjct: 77 NEKIVPGLTHWQSPNFHAYFPASSSNAGLLGELLCSGLSVIGFTWSSSPAATELENVVVD 136 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 W+ KML LP +F G GV+Q + EA L L AAR K ++R+ + Sbjct: 137 WMAKMLNLPSSFCFSGGGG--GVLQANTCEAVLCTLAAARDKALNRVGDDQ--------I 186 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPS-----DGNFAMRASALQEALERDKAAGLI 235 KLV Y SDQ H ++ + + G++ K I S + F + + L++A+ D AGL+ Sbjct: 187 NKLVLYCSDQTHFTIHKGAKLIGIRSKNIKSITTKKENEFKLCPNDLRDAIRSDLEAGLV 246 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PF++ T+GTT D + E+G + + D+WLHVD AY GSA ICPEF+H L+GV+ D Sbjct: 247 PFYVCGTIGTTALGVVDPIKELGKVAREFDLWLHVDGAYGGSACICPEFQHYLDGVDLVD 306 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 S + N HKWLL N DC +W++ L + + +LK + + DY+ WQI L R Sbjct: 307 SISMNAHKWLLSNLDCCFLWLQSPNALIESLAAEANFLKGGSE----MVDYKDWQISLSR 362 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 RFR++KMW V R YGV L +IR V ++ FE +V D RFEI LVCF+L Sbjct: 363 RFRAIKMWMVIRRYGVSNLIEHIRSDVSMAVRFEEMVAADDRFEIVFPRKFALVCFKLSS 422 Query: 416 -------SNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 +++ L++R+NS+ K +L + F +R I S E HV W I+ Sbjct: 423 EKTPPGRDSELTRELMERVNSSGKAYLSGVQMGRIFFIRCVIGSSLTEERHVDNLWRLIQ 482 Query: 469 ELAADVL 475 E A ++ Sbjct: 483 ETAQSIV 489 >4OBV-D nrPDB Length = 490 Score = 181 bits (460), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 123/438 (28%), Positives = 200/438 (45%), Gaps = 48/438 (10%) Query: 39 RPLIPAAAPQEPDTFEDI--------INDVEKIIMPGVTHW----HSPYFFAYFPTASSY 86 +P++ A + D + I +N+V +M V + + P FF++ P +S Sbjct: 46 QPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASS 105 Query: 87 PAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQG 146 + L D++ A +P +E ++ WL K + + GGV Sbjct: 106 VSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTE--------NPGGVFVS 157 Query: 147 SASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGV-- 204 S A + AL AAR + + + AY SDQ HSSV + I G+ Sbjct: 158 GGSMANITALTAARDNKLTDIN-----------LHLGTAYISDQTHSSVAKGLRIIGITD 206 Query: 205 -KLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNK 263 +++ IP++ +F M + L+EA+E DK +G IPF ++ T GTT S D L E+ +C K Sbjct: 207 SRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKK 266 Query: 264 EDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLT 323 D+W H+D AY S + P+++ LL G ADS +++ HKWL + C+ + VK +L Sbjct: 267 HDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLF 326 Query: 324 GAFRLDPTYLKHSHQDSGLITDYRHWQI--PLGRRFRSLKMWFVFRMYGVKGLQAYIRKH 381 +F ++P YLK D I + W I L R R LK+W ++ G + + I Sbjct: 327 HSFHVNPEYLKDLEND---IDNVNTWDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHG 383 Query: 382 VQLSHEFESLVRQDPRFEICVEVILGLVCFRL-------KGSNKVNEALLQRINSAKKIH 434 QL+ E + +EI + ++ FR + + +NE + RI + Sbjct: 384 FQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAA 443 Query: 435 LVPCHLRDKFVLRFAICS 452 + L K VLR IC+ Sbjct: 444 IFTTVLNGKTVLR--ICA 459 >2OKJ-A nrPDB Length = 504 Score = 144 bits (364), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 95/354 (26%), Positives = 166/354 (46%), Gaps = 16/354 (4%) Query: 50 PDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASP 109 P++ E I+ D + GV H P FF T + + L F++ +P Sbjct: 70 PESLEQILVDCRDTLKYGVRTGH-PRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAP 128 Query: 110 ACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQA 169 +E + L KM E+ + + +G G+ + + + +++AAR K ++ Sbjct: 129 VFVLMEQIT---LKKMREI----VGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKT 181 Query: 170 ASPELTQAAIMEKLVAYSSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEAL 226 A + KLV ++S+Q+H S+++AG G + I + + + + + Sbjct: 182 KG-----MAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKI 236 Query: 227 ERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRH 286 K G +PF++ AT GTT +FD + E+ IC K ++WLHVDAA+ G + + RH Sbjct: 237 LEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRH 296 Query: 287 LLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDY 346 LNG+E A+S +NPHK + V CSA+ VK++ L G ++ YL + + D Sbjct: 297 KLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDT 356 Query: 347 RHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEI 400 I GR K W +++ G G + I K ++L+ + ++ FE+ Sbjct: 357 GDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEM 410 >2OKK-A nrPDB Length = 497 Score = 144 bits (362), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 93/360 (25%), Positives = 168/360 (46%), Gaps = 20/360 (5%) Query: 49 EPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAAS 108 +P E+I+ + + + H P +F T + AD L F++ + Sbjct: 65 QPQNLEEILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIA 123 Query: 109 PACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQ 168 P LE V + + +++ P G G G+ + + + A++ AR K+ Sbjct: 124 PVFVLLEYVTLKKMREIIGWP-------GGSGDGIFSPGGAISNMYAMMIARFKMF---- 172 Query: 169 AASPELTQA--AIMEKLVAYSSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQ 223 PE+ + A + +L+A++S+ +H S+++ IG + I D M S L+ Sbjct: 173 ---PEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLE 229 Query: 224 EALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPE 283 + K G +PF + AT GTT +FD LL V IC K IW+HVDAA+ G + + Sbjct: 230 RRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRK 289 Query: 284 FRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLI 343 + L+GVE A+S +NPHK + V CSA+ V++ + ++ +YL + L Sbjct: 290 HKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLS 349 Query: 344 TDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVE 403 D + GR K+W ++R G G +A++ K ++L+ ++++ +E+ + Sbjct: 350 YDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFD 409 >6ENZ-A nrPDB Length = 530 Score = 139 bits (350), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 99/383 (25%), Positives = 177/383 (46%), Gaps = 23/383 (6%) Query: 35 PGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADML 94 P LR L+ ++ + ++ + +I V H P FF Y ++ A ++ Sbjct: 86 PEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNH-PRFFNQLYAGLDYYSLAARII 144 Query: 95 CGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLV 154 A+ +++ SP +E + L KM+E EG G+ S + + Sbjct: 145 TEALNPSIYTYEVSPVFLLVEEAV---LKKMIECVGW------KEGDGIFNPGGSVSNMC 195 Query: 155 ALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGL---IGGVKLKAI 209 A+ AR + P++ + + + +L+ ++S + H S+++A IG + + Sbjct: 196 AMNLARYR-------HCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFV 248 Query: 210 PSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLH 269 +DG M L++ + + + G +PF + AT GTT +FD L E+ +C + +WLH Sbjct: 249 ETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLH 308 Query: 270 VDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD-LTGAFRL 328 VDA++ GSA + + R LL+G+ ADS +NPHK L+ CSA+ VK ++D L + Sbjct: 309 VDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSA 368 Query: 329 DPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEF 388 TYL + + D I RR + K W ++ G GL+ + + LS Sbjct: 369 KATYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYL 428 Query: 389 ESLVRQDPRFEICVEVILGLVCF 411 +++ F++ +E VCF Sbjct: 429 VDEIKKREGFKLLMEPEYTNVCF 451 >4RIT-B nrPDB Length = 486 Score = 137 bits (346), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 116/420 (27%), Positives = 194/420 (46%), Gaps = 37/420 (8%) Query: 2 NASEFRRRGKEMVDYMANYMEGIEGRQVYPDVE--PGYLRPLIPAAAPQEPDTFEDIIND 59 N +E R +++VD + + G R P+ PG + IP AA E + I + Sbjct: 21 NRNEVERLVQQVVDLILAKLTGAAERPPMPETVDLPGPI--TIPEAAATEATLLQAIRDM 78 Query: 60 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM 119 V+ + P +P + + + A+L D++ A+ S SP+ + LET+++ Sbjct: 79 VDGSMNPA-----NPGYIGHMDPMPATMAILGDLVAAAVNNNMLSLEMSPSFSRLETLLL 133 Query: 120 DWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179 + + L + + GGV+ S A L AL AR ++ P +T + Sbjct: 134 RAIAGLFGLGE--------QAGGVLTSGGSLANLQALAVARNVAFDSVE---PGIT--GL 180 Query: 180 MEKLVAYSSDQAHSSVERAGLIGGVKLKA-IP--SDGNFAMRASALQEALERDKAAGLIP 236 ++ V ++S+ AH+S+++A ++ G+ A IP + + M L+ +++ + AG P Sbjct: 181 AQRPVIFASEAAHTSLQKAAMLLGLGTAAVIPVRATADSRMDPEDLRARIDQARGAGQHP 240 Query: 237 FFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADS 296 F +VAT GTTT + D L E+G I + +W HVDAAY G+ R L G+E ADS Sbjct: 241 FCVVATAGTTTTGNIDPLAEIGAIAREHGLWFHVDAAYGGALVFSERHRWRLAGIEQADS 300 Query: 297 FNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGL----ITDYRHWQIP 352 FNP KWL V C+ + + L AFR+ Y++ + L + RH + Sbjct: 301 ITFNPQKWLYVAKTCAMVLFRDAGVLERAFRIPAPYMRATDGFINLGEIGVQGTRHADV- 359 Query: 353 LGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFR 412 +K+W + G +G I +L+ VRQ P + E+ +VCFR Sbjct: 360 -------VKLWLTLQHIGQQGYARLIDDGYRLAERVVEGVRQRPFLRLAGEIDTNIVCFR 412 >5O5C-A nrPDB Length = 519 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 106/432 (24%), Positives = 181/432 (41%), Gaps = 17/432 (3%) Query: 4 SEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYL-RPLIPAAAPQEPDTFEDIINDVEK 62 S + R+ ++++ M ++G+E + + + P L R Q + E + +++K Sbjct: 35 SAWARQTEQVLALMTETVKGVE--KPFSGILPHELAREFSGVDLDQSLGSNEAALEELKK 92 Query: 63 IIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWL 122 + + +H P + A+ P++LA+ + A+ +W S T +E ++DW Sbjct: 93 LYLRDAVWFHHPKYVAHLNCPVVLPSLLAEQIMAAVNSSVDTWDQSAGGTLIEQKVIDWT 152 Query: 123 GKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTK--VIHRLQAASPELTQAAIM 180 + LP G+ +++ L+A+L AR H Sbjct: 153 LSRIGLPAG--------ADGIFTSGGTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDA 204 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKA-IPSDGN--FAMRASALQEALERDKAAGLIPF 237 K ++S +H S++++ I G+ A IP D + + M L++ ++R GLIP Sbjct: 205 AKWRVFTSKLSHFSIQKSMAILGLGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPV 264 Query: 238 FMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSF 297 +VAT GTT S D L + +C +W+HVDAAY + R L G+E ADS Sbjct: 265 AVVATSGTTDFGSIDPLGAISELCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSV 324 Query: 298 NFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRF 357 + HK C A +V+ + L+ S Q G + + I RRF Sbjct: 325 TVDYHKSFFQTVSCGAFFVRDKHHLSHVTHHADYLNPLSAQQEG-TPNLVNKSIQTTRRF 383 Query: 358 RSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSN 417 +LKMW R+ G L + L+ L+ P E+ L FR Sbjct: 384 DALKMWLTLRVSGPMALGNAFDDILALTQIAHQLLNAHPAIEVLHVPELTTQIFRYVPRP 443 Query: 418 KVNEALLQRINS 429 +N+AL IN+ Sbjct: 444 GMNDALTDEINT 455 >2JIS-A nrPDB Length = 515 Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 94/384 (24%), Positives = 172/384 (44%), Gaps = 23/384 (5%) Query: 34 EPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADM 93 EP L+ L+ + ++ + I+ +I V H P FF + A+ + Sbjct: 70 EPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGH-PRFFNQLFSGLDPHALAGRI 128 Query: 94 LCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATL 153 + ++ +++ +P +E ++ L +A + +G+G GS S Sbjct: 129 ITESLNTSQYTYEIAPVFVLMEEEVLRKL-------RALVGWSSGDGIFCPGGSISNMYA 181 Query: 154 VALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGL---IGGVKLKA 208 V L AR + P+ Q + + L ++S + H S+++ +G ++ Sbjct: 182 VNL--ARYQ-------RYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRV 232 Query: 209 IPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWL 268 + +D M L+ + +A G +PF + AT GTT +FD L + +C + +WL Sbjct: 233 VKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 292 Query: 269 HVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTG-AFR 327 HVDAA+ GS + RHLL+G++ ADS +NPHK L CSA+ ++ ++L Sbjct: 293 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHG 352 Query: 328 LDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHE 387 +YL + + D + GRR LK+W +++ G +GL+ I + L+ Sbjct: 353 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARY 412 Query: 388 FESLVRQDPRFEICVEVILGLVCF 411 +++ FE+ +E VCF Sbjct: 413 LVEEMKKREGFELVMEPEFVNVCF 436 >2QMA-A nrPDB Length = 497 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 119/486 (24%), Positives = 214/486 (44%), Gaps = 28/486 (5%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDT-FEDIIND 59 + ++EF M + E + Y ++P L I A + + +I+D Sbjct: 29 LGSAEFASVMSHTTSAMKSVFEQVNAP--YSGMDPKALEDAINAVDLDNKNAPLKSVIDD 86 Query: 60 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM 119 V +++ P A+ T PA+ A+ + A+ SW + + T +E ++ Sbjct: 87 VAELVAKNAIFTQHPDCIAHLHTPPLMPAVAAEAMIAALNQSMDSWDQASSATYVEQKVV 146 Query: 120 DWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAAS-PELTQAA 178 +WL K L+EKA G+ +++ + L+ AR + +L S +L Sbjct: 147 NWL-----CDKYDLSEKAD---GIFTSGGTQSNQMGLMLARDWIADKLSGHSIQKLGLPD 198 Query: 179 IMEKLVAYSSDQAHSSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLI 235 +KL S ++H +V+++ G+ KA+ ++ + M + L E + + KA GLI Sbjct: 199 YADKLRIVCSKKSHFTVQKSASWMGLGEKAVMTVDANADGTMDITKLDEVIAQAKAEGLI 258 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PF +V T GTT + D+L + + K D+W+HVD AY G A I + L GVE A Sbjct: 259 PFAIVGTAGTTDHGAIDDLDFIADMAVKHDMWMHVDGAYGG-ALILSSHKSRLKGVERAH 317 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRL-DPTYLKHSHQDSGLITDYRHWQIPLG 354 S + + HK C A+ V +++ F L YL H + + D I Sbjct: 318 SISVDFHKLFYQTISCGALLVNDKSNFK--FLLHHADYLNREHDELPNLVDK---SIATT 372 Query: 355 RRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLK 414 +RF +LK++ + G K L + + E ++R + +FE+ E L V FR Sbjct: 373 KRFDALKVFMTMQNVGPKALGDMYDHLLAQTLEVADMIRTNDQFELLAEPSLSTVLFRAT 432 Query: 415 GS----NKVNEAL-LQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKE 469 +++N+AL L+ + + L + K L+F I + + ++ + I Sbjct: 433 HETADLDELNKALRLEALTRGIAV-LGETIVDGKTALKFTILNPCLTTSDFESLLSKINM 491 Query: 470 LAADVL 475 LA +++ Sbjct: 492 LAVELV 497 >3F9T-A nrPDB Length = 397 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 66/312 (21%), Positives = 126/312 (40%), Gaps = 35/312 (11%) Query: 124 KMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKL 183 K + L + LN K + G I +EA L+AL + + + + I+ + Sbjct: 73 KAVALLGSLLNNK--DAYGHIVSGGTEANLMALRCIKNIWREKRRKGLSKNEHPKIIVPI 130 Query: 184 VAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATL 243 A H S E+ + ++ P ++ + +++A+E G+I Sbjct: 131 TA------HFSFEKGREMMDLEYIYAPIKEDYTIDEKFVKDAVEDYDVDGII-----GIA 179 Query: 244 GTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEF-------ADS 296 GTT + DN+ E+ I + +I++HVDAA+ G + ++ GV + DS Sbjct: 180 GTTELGTIDNIEELSKIAKENNIYIHVDAAFGGLVIPFLDDKYKKKGVNYKFDFSLGVDS 239 Query: 297 FNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRR 356 +PHK + K D Y ++ D+ +T+ R I LG R Sbjct: 240 ITIDPHKMGHCPIPSGGILFK-----------DIGYKRYLDVDAPYLTETRQATI-LGTR 287 Query: 357 --FRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLK 414 F + V R G +G + + + ++ + ++++ F+ +E IL +V + Sbjct: 288 VGFGGACTYAVLRYLGREGQRKIVNECMENTLYLYKKLKEN-NFKPVIEPILNIVAIEDE 346 Query: 415 GSNKVNEALLQR 426 +V + L R Sbjct: 347 DYKEVCKKLRDR 358 >5HSI-A nrPDB Length = 634 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 41/167 (24%), Positives = 61/167 (36%), Gaps = 42/167 (25%) Query: 192 HSSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTT- 247 H S +A I G+ L + P D N+ M AL E++ R AA P V + +T Sbjct: 241 HYSWMKAADIIGIGLDQVVPVPIDSNYRMDIQAL-ESIIRKYAAEKTPILGVVGVAGSTE 299 Query: 248 ---CCSFDNLLEVGPICNKEDIW--LHVDAAYAGSA------------------------ 278 D ++ + KE I+ LHVDAAY G A Sbjct: 300 EGAVDGIDKIVALRQKLQKEGIYFYLHVDAAYGGYARALFLDEDDQFIPYKNLQKVHAEN 359 Query: 279 --------FICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVK 317 +I PE + A+S +PHK V + + ++ Sbjct: 360 HVFTEDKEYIKPEVYAAYKAFDQAESITIDPHKMGYVPYSAGGIVIQ 406 >1IAY-A nrPDB Length = 428 Score = 35.0 bits (79), Expect = 0.067, Method: Compositional matrix adjust. Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 9/89 (10%) Query: 203 GVKLKAI--PSDGNFAMRASALQEALERD-----KAAGLIPFFMVATLGTTTCCSFDNLL 255 GV+L I S NF + + A++EA E K GLI LGTT D L Sbjct: 154 GVQLIPIHCESSNNFKITSKAVKEAYENAQKSNIKVKGLILTNPSNPLGTTL--DKDTLK 211 Query: 256 EVGPICNKEDIWLHVDAAYAGSAFICPEF 284 V N+ +I L D YA + F P+F Sbjct: 212 SVLSFTNQHNIHLVCDEIYAATVFDTPQF 240 >3MAF-B nrPDB Length = 518 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 21/125 (16%) Query: 190 QAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDK--AAGLIPFFMVATLGTTT 247 AH++ ++A G+KL P D ++ +A++EA+ + AG P + + Sbjct: 204 SAHAAFDKAAQYFGIKLVRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVV---- 259 Query: 248 CCSFDNLLEVGPICNKEDIWLHVDAAYAG--------SAFICPEFRHLLNGVEFADSFNF 299 D + E+ + + I HVDA G + P F L GV S + Sbjct: 260 ----DPIPEIAALAAEHGIGCHVDACLGGFILPWAERLGYPVPPFDFRLEGVT---SVSA 312 Query: 300 NPHKW 304 + HK+ Sbjct: 313 DTHKY 317 >4W8I-A nrPDB Length = 551 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 13/97 (13%) Query: 189 DQAHSSVERAGLIGGVKLKAIPSDGNF-AMRASALQEALERDKAA--GLIPFFMVATLGT 245 + AH++ ++A + G L +P D A+ + + + R+ A G P FM Sbjct: 195 ETAHAAFKKAAELTGAILITVPVDKKTGAVNPNVMSSYITRNTAVMVGSAPSFMNGI--- 251 Query: 246 TTCCSFDNLLEVGPICNKEDIWLHVDAAYAG--SAFI 280 D + E+G + K+++ HVDA G +AF+ Sbjct: 252 -----HDPISELGQLAKKKNVPFHVDACLGGFLTAFL 283 >4QQ1-A nrPDB Length = 543 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 18/72 (25%) Query: 200 LIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGP 259 L+ GV+L +PS+GN A A Q +E++ + T CCS + + G Sbjct: 333 LVDGVELSLLPSEGNKA----AFQHEIEQN------------GVKATVCCSNLDYMSFGK 376 Query: 260 IC--NKEDIWLH 269 + NK+D++L Sbjct: 377 LSKENKDDMFLQ 388 >2HIX-A nrPDB Length = 621 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 4/34 (11%) Query: 12 EMVDYMANYMEG----IEGRQVYPDVEPGYLRPL 41 ++VDY++ Y+EG IEG V D E G +RP Sbjct: 311 DVVDYVSKYIEGKEFIIEGEIVAIDPESGEMRPF 344 >4Q6R-A nrPDB Length = 511 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 30/135 (22%), Positives = 53/135 (39%), Gaps = 18/135 (13%) Query: 142 GVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLI 201 G + +E+ L+A A R + +PE+ + AH++ +A Sbjct: 147 GCVTSGGTESILMACKAYRDLAFEK-GIKTPEIV-----------APQSAHAAFNKAASY 194 Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 G+K+ +P + A++ A+ R+ A +V + D + EV + Sbjct: 195 FGMKIVRVPLTKMMEVDVRAMRRAISRNTA------MLVCSTPQFPHGVIDPVPEVAKLA 248 Query: 262 NKEDIWLHVDAAYAG 276 K I LHVDA G Sbjct: 249 VKYKIPLHVDACLGG 263 >5HB1-A nrPDB Length = 830 Score = 28.1 bits (61), Expect = 9.2, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 25/50 (50%) Query: 117 VMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHR 166 VM W+ ++L L + AG G + G+AS+A +A L K + R Sbjct: 777 VMGSWVSELLGRADQVLTQIAGTGATLRGGAASDAEEIASLRRTVKGLKR 826 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3RBF-A nrPDB 739 0.0 1JS3-A nrPDB 694 0.0 3K40-A nrPDB 655 0.0 4E1O-A nrPDB 640 0.0 6JRL-A nrPDB 631 0.0 6EEI-A nrPDB 624 e-179 6EEW-A nrPDB 606 e-174 6EEM-B nrPDB 600 e-172 6EEQ-A nrPDB 577 e-165 5O5C-A nrPDB 464 e-131 2OKJ-A nrPDB 464 e-131 6ENZ-A nrPDB 455 e-128 2OKK-A nrPDB 454 e-128 2JIS-A nrPDB 446 e-125 2QMA-A nrPDB 446 e-125 4OBV-D nrPDB 419 e-117 4RIT-B nrPDB 400 e-112 3F9T-A nrPDB 274 7e-74 Sequences not found previously or not previously below threshold: 5HSI-A nrPDB 127 8e-30 5K1R-A nrPDB 119 3e-27 3MAF-B nrPDB 112 3e-25 3HBX-A nrPDB 104 1e-22 4Q6R-A nrPDB 104 1e-22 3MC6-C nrPDB 86 5e-17 5GP4-C nrPDB 82 5e-16 4W8I-A nrPDB 80 2e-15 2DGM-A nrPDB 79 3e-15 5WT2-A nrPDB 57 2e-08 3LVM-A nrPDB 56 3e-08 1SVV-A nrPDB 55 6e-08 1WYV-B nrPDB 54 1e-07 2E7J-A nrPDB 54 2e-07 5WGB-A nrPDB 52 7e-07 5XT5-A nrPDB 49 5e-06 5V1X-E nrPDB 47 2e-05 3WGB-A nrPDB 44 2e-04 4ISY-A nrPDB 43 4e-04 2Z67-A nrPDB 41 0.001 1M6S-A nrPDB 41 0.001 4EB7-A nrPDB 40 0.002 3NNK-A nrPDB 39 0.005 3KGX-A nrPDB 39 0.005 6ONN-A nrPDB 38 0.008 4LNJ-A nrPDB 38 0.010 2DR1-A nrPDB 38 0.010 3ISL-A nrPDB 38 0.011 2EPJ-A nrPDB 38 0.011 5JAY-A nrPDB 37 0.014 3WKR-A nrPDB 37 0.021 5LUC-A nrPDB 37 0.021 2CH1-A nrPDB 37 0.025 5VYE-A nrPDB 36 0.032 1O69-A nrPDB 36 0.035 3UWC-A nrPDB 35 0.048 2Z9W-A nrPDB 35 0.062 5K8B-A nrPDB 35 0.070 3HL2-A nrPDB 35 0.083 1V72-A nrPDB 34 0.11 3WY7-A nrPDB 34 0.12 2C81-A nrPDB 34 0.12 4PIW-A nrPDB 34 0.13 2DOU-A nrPDB 34 0.15 2HUU-A nrPDB 33 0.25 1VJO-A nrPDB 33 0.25 6MQH-A nrPDB 33 0.26 5A9K-A nrPDB 33 0.29 2GXA-A nrPDB 33 0.29 3LWS-A nrPDB 33 0.34 3PJ0-A nrPDB 33 0.35 1IAY-A nrPDB 33 0.35 2OGE-A nrPDB 32 0.43 3BC8-A nrPDB 32 0.44 6MRE-A nrPDB 32 0.44 6HRH-B nrPDB 32 0.68 2YRI-A nrPDB 31 0.93 5W1B-A nrPDB 31 0.99 6FYQ-A nrPDB 31 1.0 2GMS-A nrPDB 31 1.0 2ZC0-A nrPDB 31 1.1 1WYT-A nrPDB 31 1.1 4LHD-A nrPDB 31 1.2 1DJ9-A nrPDB 31 1.3 4WB0-B nrPDB 31 1.5 3CAI-A nrPDB 31 1.5 2EH6-A nrPDB 31 1.5 5ZME-A nrPDB 30 1.7 2RIL-A nrPDB 30 1.8 6CA8-A nrPDB 30 1.8 5G0A-A nrPDB 30 2.4 2X8U-A nrPDB 30 2.6 2BWN-A nrPDB 30 2.6 6CJQ-A nrPDB 29 4.8 >3RBF-A nrPDB Length = 480 Score = 739 bits (1909), Expect = 0.0, Method: Composition-based stats. Identities = 479/480 (99%), Positives = 480/480 (100%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 MNASEFRRRGKEMVDY+ANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV Sbjct: 1 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD Sbjct: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM Sbjct: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV Sbjct: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN Sbjct: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL Sbjct: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE Sbjct: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480 >1JS3-A nrPDB Length = 486 Score = 694 bits (1792), Expect = 0.0, Method: Composition-based stats. Identities = 420/468 (89%), Positives = 448/468 (95%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 MNAS+FRRRGKEMVDYMA+Y+EGIEGRQVYPDV+PGYLRPLIPA APQEPDTFEDI+ DV Sbjct: 1 MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDV 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD Sbjct: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKML+LP+AFL +AGEGGGVIQGSASEATLVALLAARTKV+ RLQAASP LTQ A++ Sbjct: 121 WLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVVRRLQAASPGLTQGAVL 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 EKLVAY+SDQAHSSVERAGLIGGVKLKAIPSDG FAMRASALQEALERDKAAGLIPFF+V Sbjct: 181 EKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTT+CCSFDNLLEVGPIC++EDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN Sbjct: 241 ATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKWLLVNFDCSAMWVK+RTDLTGAF+LDP YLKHSHQ SGLITDYRHWQ+PLGRRFRSL Sbjct: 301 PHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 KMWFVFRMYGVKGLQAYIRKHVQLSHEFE+ V QDPRFE+C EV LGLVCFRLKGS+ +N Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLN 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 EALL+RINSA+KIHLVPC LR +FVLRFAICSR VES HV+ AWEHI+ Sbjct: 421 EALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIR 468 >3K40-A nrPDB Length = 475 Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats. Identities = 290/479 (60%), Positives = 368/479 (76%), Gaps = 4/479 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M A EF+ K MVD++A Y+E I R+V P+V+PGYL+PLIP AAP++P+ ++D++ D+ Sbjct: 1 MEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDI 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 E++IMPGVTHWHSP F AYFPTA+SYPA++ADML GAI CIGF+W ASPACTELE VMMD Sbjct: 61 ERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WLGKMLELP FL G+GGGVIQG+ASE+TLVALL A+ K + ++ PE + I+ Sbjct: 121 WLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTIL 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 KLV Y SDQAHSSVERAGL+GGVKL+++ S N MR +AL++A+E+D A GLIPF+ V Sbjct: 181 GKLVGYCSDQAHSSVERAGLLGGVKLRSVQS-ENHRMRGAALEKAIEQDVAEGLIPFYAV 239 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 TLGTT C+FD L E GP+ NK ++W+HVDAAYAGSAFICPE+RHL+ G+E ADSFNFN Sbjct: 240 VTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFN 299 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 PHKW+LVNFDCSAMW+K + + AF +DP YLKH Q S DYRHWQIPLGRRFR+L Sbjct: 300 PHKWMLVNFDCSAMWLKDPSWVVNAFNVDPLYLKHDMQGS--APDYRHWQIPLGRRFRAL 357 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 K+WFV R+YGV+ LQA+IR+H + +F L D RFE+ E+ +GLVCFRLKGSN+ N Sbjct: 358 KLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCFRLKGSNERN 417 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAER 479 EALL+RIN IHLVP ++D + LR AICSR +S ++ +W+ + AAD + E+ Sbjct: 418 EALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQSEDMEYSWKEV-SAAADEMEQEQ 475 >4E1O-A nrPDB Length = 481 Score = 640 bits (1652), Expect = 0.0, Method: Composition-based stats. Identities = 248/478 (51%), Positives = 347/478 (72%), Gaps = 3/478 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M E+R RG+EMVDY+ Y+ + R+V PDV+PGYLR +P +AP++PD+++ I D+ Sbjct: 6 MEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDI 65 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 E+IIMPGV HW SP+ AY+P +S+P++L DML AI C+GF+WA+SPACTELE +MD Sbjct: 66 ERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMD 125 Query: 121 WLGKMLELPKAFLNEK-AGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179 WL KML LP+ FL+ + +GGGV+Q + SE+TL+ALLAAR I ++ + P+ ++++ Sbjct: 126 WLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESSL 185 Query: 180 MEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFM 239 +LVAY+SDQAHSSVE+AGLI VK+K +P D NF++R ALQ+A+E DK GL+P F+ Sbjct: 186 NARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFV 245 Query: 240 VATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNF 299 ATLGTT C+FD L E+GPIC +E +WLH+DAAYAG+AF+CPEFR L G+E+ADSF F Sbjct: 246 CATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTF 305 Query: 300 NPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRS 359 NP KW++V+FDC+ WVK + L F ++P YL+H+ +SG+ TD+ HWQIPL RRFRS Sbjct: 306 NPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHA--NSGVATDFMHWQIPLSRRFRS 363 Query: 360 LKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKV 419 +K+WFV R +GVK LQA++R +++ FESLVR DP FEI + LGLV FRLKG N + Sbjct: 364 VKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNSL 423 Query: 420 NEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRA 477 E +L+ I A ++ L+P ++DK ++RF + S+ + R W I++ A +L Sbjct: 424 TENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQ 481 >6JRL-A nrPDB Length = 510 Score = 631 bits (1628), Expect = 0.0, Method: Composition-based stats. Identities = 228/479 (47%), Positives = 327/479 (68%), Gaps = 1/479 (0%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M+A EFR GK +DY+A+Y+E I V P+VEPGYL L+P P+EP+ ++D++ D+ Sbjct: 1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDI 60 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 ++I PG+THW SP+ AY+PT++SYP+++ +ML G IGFSW SPACTELE V+MD Sbjct: 61 SRVIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMD 120 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WL K L+LP F + G GGGVIQGSASEA LVA+LAAR + + + + PEL+++ + Sbjct: 121 WLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVR 180 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 +LVAYSSDQ++S +E+AG++ + ++ +P+ +F +R L+ A+E D AAG IP V Sbjct: 181 GRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICV 240 Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 ATLGTT C++D++ + +C + +WLHVDAAYAG AF E L G++ DS NFN Sbjct: 241 ATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFN 300 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 HK++LVNFDCSAMW++ + +F +D YLKH H+ I D+RHWQIPLGRRFR+L Sbjct: 301 LHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRAL 360 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 K+W FR G +GL+ ++RKH++L+ +FE LV +D RFE+ LGLVCFR KG N++ Sbjct: 361 KVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCFRPKGDNEIT 420 Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAER 479 LLQR+ KKI++V + LRF +C +++ + AW+ I+ D L+AE+ Sbjct: 421 TQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMDTKASDIDFAWQEIESQLTD-LQAEQ 478 >6EEI-A nrPDB Length = 490 Score = 624 bits (1610), Expect = e-179, Method: Composition-based stats. Identities = 236/487 (48%), Positives = 315/487 (64%), Gaps = 22/487 (4%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M++ + R G MVD++A+Y + IE V V+PGYL L+P +AP P+T + +++DV Sbjct: 12 MDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDSAPDHPETLDQVLDDV 71 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 I+PGVTHW SP FFAY+P+ SS L +ML +G +GFSW SPA TELE +++D Sbjct: 72 RAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPAATELEMIVLD 131 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 W+ K+L LP+ F+++ G GGGVIQGSASEA LV L+AAR KV+ + + Sbjct: 132 WVAKLLNLPEQFMSK--GNGGGVIQGSASEAVLVVLIAARDKVLRSVGKN--------AL 181 Query: 181 EKLVAYSSDQAHSSVERAGLIGGV-----KLKAIPSDGNFAMRASALQEALERDKAAGLI 235 EKLV YSSDQ HS++++A I G+ ++ S N+A+R +LQEA+ RD AGLI Sbjct: 182 EKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLI 241 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PFF+ A +GTT+ + D L +G I N IW HVDAAYAGSA ICPE+R ++GVE AD Sbjct: 242 PFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETAD 301 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 SFN N HKW L NFDCS +WVK + LT A +P +LK+ + L+ DY+ WQIPLGR Sbjct: 302 SFNMNAHKWFLTNFDCSLLWVKDQDSLTLALSTNPEFLKNKASQANLVVDYKDWQIPLGR 361 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRL-- 413 RFRSLK+W V R+YG + L++YIR H++L+ EFE LV QDP FEI I LVCFRL Sbjct: 362 RFRSLKLWMVLRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVP 421 Query: 414 -----KGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 K N N LL +NS+ K+ + L K VLR AI + E HV+ AW+ I+ Sbjct: 422 VKDEEKKCNNRNRELLDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQ 481 Query: 469 ELAADVL 475 E A+ +L Sbjct: 482 EEASYLL 488 >6EEW-A nrPDB Length = 500 Score = 606 bits (1562), Expect = e-174, Method: Composition-based stats. Identities = 205/487 (42%), Positives = 303/487 (62%), Gaps = 21/487 (4%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 + A EFR++ MVD++A+Y + +E V +VEPGYLR IP AP P+ +DI+ D+ Sbjct: 22 LEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDI 81 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 +K I+PG+T+W SP F+A+FP S A L +ML A+ +GF+W +SPA TELE ++MD Sbjct: 82 QKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMD 141 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 WL ++L+LPK+F+ +G GGGVIQ + SE+ L ++AAR + + +L + Sbjct: 142 WLAQILKLPKSFMF--SGTGGGVIQNTTSESILCTIIAARERALEKLG--------PDSI 191 Query: 181 EKLVAYSSDQAHSSVERAGLIGGV---KLKAIPS--DGNFAMRASALQEALERDKAAGLI 235 KLV Y SDQ H+ + + G+ ++ IP+ + +F + L++ +E D AAG + Sbjct: 192 GKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYV 251 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 P F+ ATLGTT+ + D + + I N+ IW+HVDAAYAGSA ICPEFRH L+G+E D Sbjct: 252 PLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVD 311 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 S + +PHKWLL DC+ +WVK+ L A +P YLK+ D + D+++WQI GR Sbjct: 312 SLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGR 371 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 +FRSLK+W + R YGV LQ++IR V ++ FE VR D RFEI V LVCFRLK Sbjct: 372 KFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKP 431 Query: 416 S------NKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKE 469 +VN+ LL +NS ++++ + ++LR A+ S E HV+R W+ I++ Sbjct: 432 DVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQK 491 Query: 470 LAADVLR 476 L D+L+ Sbjct: 492 LTDDLLK 498 >6EEM-B nrPDB Length = 512 Score = 600 bits (1548), Expect = e-172, Method: Composition-based stats. Identities = 201/501 (40%), Positives = 302/501 (60%), Gaps = 32/501 (6%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 ++ EFRR+G ++D++A+Y + +E V VEPGYL+ +P +AP P++ E I+ DV Sbjct: 20 LDPDEFRRQGHMIIDFLADYYKNVEKYPVRSQVEPGYLKKRLPESAPYNPESIETILEDV 79 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 I+PG+THW SP +FAYFP++ S L +ML +GF+W +SPA TELE+++M+ Sbjct: 80 TNDIIPGLTHWQSPNYFAYFPSSGSIAGFLGEMLSTGFNVVGFNWMSSPAATELESIVMN 139 Query: 121 WLGKMLELPKAFLNEKAGEGGG--VIQGSASEATLVALLAARTKVIHRLQAASPELTQAA 178 WLG+ML LPK+FL G GG V+QG+ EA L L AAR K+++++ + Sbjct: 140 WLGQMLTLPKSFLFSSDGSSGGGGVLQGTTCEAILCTLTAARDKMLNKIGREN------- 192 Query: 179 IMEKLVAYSSDQAHSSVERAGLIGGVK---LKAIPSD--GNFAMRASALQEALERDKAAG 233 + KLV Y+SDQ H ++++A I G+ ++AI + NF + ++LQ A+ D +G Sbjct: 193 -INKLVVYASDQTHCALQKAAQIAGINPKNVRAIKTSKATNFGLSPNSLQSAILADIESG 251 Query: 234 LIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEF 293 L+P F+ AT+GTT+ + D + + + IW+H+DAAYAGSA ICPEFRH ++GVE Sbjct: 252 LVPLFLCATVGTTSSTAVDPIGPLCAVAKLYGIWVHIDAAYAGSACICPEFRHFIDGVED 311 Query: 294 ADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPL 353 ADSF+ N HKW DC +WVK L A P YLK+ +S + DY+ WQI L Sbjct: 312 ADSFSLNAHKWFFTTLDCCCLWVKDSDSLVKALSTSPEYLKNKATESKQVIDYKDWQIAL 371 Query: 354 GRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRL 413 RRFRS+K+W V R YGV L+ ++R HV+++ F+ L+ D RFEI V +VCFRL Sbjct: 372 SRRFRSMKLWLVLRSYGVANLRTFLRSHVKMAKHFQGLIGMDNRFEIVVPRTFAMVCFRL 431 Query: 414 KG-----------------SNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVE 456 K +N+VN LL+ +N++ KI++ + +++RFA+ + E Sbjct: 432 KPTAIFKQKIVDNDYIEDQTNEVNVKLLESVNASGKIYMTHAVVGGVYMIRFAVGATLTE 491 Query: 457 SAHVQRAWEHIKELAADVLRA 477 HV AW+ ++E +L A Sbjct: 492 ERHVTGAWKVVQEHTDAILGA 512 >6EEQ-A nrPDB Length = 490 Score = 577 bits (1486), Expect = e-165, Method: Composition-based stats. Identities = 187/487 (38%), Positives = 276/487 (56%), Gaps = 26/487 (5%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60 M+ +E K +VD++ Y + +E R V P V+PG+L +P AP ++ E I++DV Sbjct: 17 MDLTELSTESKLVVDFITQYYQTLETRPVQPRVKPGFLTGQLPDKAPFHGESMEVILSDV 76 Query: 61 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120 + I+PG+THW SP F AYFP +SS +L ++LC + IGF+W++SPA TELE V++D Sbjct: 77 NEKIVPGLTHWQSPNFHAYFPASSSNAGLLGELLCSGLSVIGFTWSSSPAATELENVVVD 136 Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180 W+ KML LP +F G G V+Q + EA L L AAR K ++R+ + Sbjct: 137 WMAKMLNLPSSFCFSGGGGG--VLQANTCEAVLCTLAAARDKALNRVGDDQ--------I 186 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPS-----DGNFAMRASALQEALERDKAAGLI 235 KLV Y SDQ H ++ + + G++ K I S + F + + L++A+ D AGL+ Sbjct: 187 NKLVLYCSDQTHFTIHKGAKLIGIRSKNIKSITTKKENEFKLCPNDLRDAIRSDLEAGLV 246 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PF++ T+GTT D + E+G + + D+WLHVD AY GSA ICPEF+H L+GV+ D Sbjct: 247 PFYVCGTIGTTALGVVDPIKELGKVAREFDLWLHVDGAYGGSACICPEFQHYLDGVDLVD 306 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 S + N HKWLL N DC +W++ L + + +LK + + DY+ WQI L R Sbjct: 307 SISMNAHKWLLSNLDCCFLWLQSPNALIESLAAEANFLKGGSE----MVDYKDWQISLSR 362 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 RFR++KMW V R YGV L +IR V ++ FE +V D RFEI LVCF+L Sbjct: 363 RFRAIKMWMVIRRYGVSNLIEHIRSDVSMAVRFEEMVAADDRFEIVFPRKFALVCFKLSS 422 Query: 416 -------SNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK 468 +++ L++R+NS+ K +L + F +R I S E HV W I+ Sbjct: 423 EKTPPGRDSELTRELMERVNSSGKAYLSGVQMGRIFFIRCVIGSSLTEERHVDNLWRLIQ 482 Query: 469 ELAADVL 475 E A ++ Sbjct: 483 ETAQSIV 489 >5O5C-A nrPDB Length = 519 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 107/478 (22%), Positives = 191/478 (39%), Gaps = 25/478 (5%) Query: 4 SEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYL-RPLIPAAAPQEPDTFEDIINDVEK 62 S + R+ ++++ M ++G+E + + + P L R Q + E + +++K Sbjct: 35 SAWARQTEQVLALMTETVKGVE--KPFSGILPHELAREFSGVDLDQSLGSNEAALEELKK 92 Query: 63 IIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWL 122 + + +H P + A+ P++LA+ + A+ +W S T +E ++DW Sbjct: 93 LYLRDAVWFHHPKYVAHLNCPVVLPSLLAEQIMAAVNSSVDTWDQSAGGTLIEQKVIDWT 152 Query: 123 GKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKV--IHRLQAASPELTQAAIM 180 + LP G+ +++ L+A+L AR H Sbjct: 153 LSRIGLPA--------GADGIFTSGGTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDA 204 Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLIPF 237 K ++S +H S++++ I G+ A+ D + M L++ ++R GLIP Sbjct: 205 AKWRVFTSKLSHFSIQKSMAILGLGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPV 264 Query: 238 FMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSF 297 +VAT GTT S D L + +C +W+HVDAAY + R L G+E ADS Sbjct: 265 AVVATSGTTDFGSIDPLGAISELCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSV 324 Query: 298 NFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRF 357 + HK C A +V+ + L+ YL + + I RRF Sbjct: 325 TVDYHKSFFQTVSCGAFFVRDKHHLSHVTH-HADYLNPLSAQQEGTPNLVNKSIQTTRRF 383 Query: 358 RSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSN 417 +LKMW R+ G L + L+ L+ P E+ L FR Sbjct: 384 DALKMWLTLRVSGPMALGNAFDDILALTQIAHQLLNAHPAIEVLHVPELTTQIFRYVPRP 443 Query: 418 KVNEALLQRIN--------SAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHI 467 +N+AL IN + + + + L+F + + +A ++ I Sbjct: 444 GMNDALTDEINTNIRKAVFRSGNAVIAGTKVNGRQYLKFTLLNPNTTAADIEDVIALI 501 >2OKJ-A nrPDB Length = 504 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 113/489 (23%), Positives = 202/489 (41%), Gaps = 39/489 (7%) Query: 12 EMVDYMANYMEGIEGR--QVYPDVEPGYLRPLI---PAAAPQEPDTFEDIINDVEKIIMP 66 E+VD + NY+ R +V P L + P++ E I+ D + Sbjct: 27 EVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKY 86 Query: 67 GVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKML 126 GV H P FF T + + L F++ +P +E + + + +++ Sbjct: 87 GVRTGH-PRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIV 145 Query: 127 ELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAY 186 + +G G+ + + + +++AAR K ++ A + KLV + Sbjct: 146 G-------WSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKG-----MAAVPKLVLF 193 Query: 187 SSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATL 243 +S+Q+H S+++AG G + I + + + + + K G +PF++ AT Sbjct: 194 TSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATA 253 Query: 244 GTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHK 303 GTT +FD + E+ IC K ++WLHVDAA+ G + + RH LNG+E A+S +NPHK Sbjct: 254 GTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHK 313 Query: 304 WLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMW 363 + V CSA+ VK++ L G ++ YL + + D I GR K W Sbjct: 314 MMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFW 373 Query: 364 FVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICV--EVILGLVCF-------RLK 414 +++ G G + I K ++L+ + ++ FE+ E VCF R Sbjct: 374 LMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGV 433 Query: 415 GSNKVNEALLQRINSAKKIHL--VPCHLRDKF-------VLRFAICSRTVESAHVQRAWE 465 + L ++ K + + R I + + + E Sbjct: 434 PDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIE 493 Query: 466 HIKELAADV 474 I+ L D+ Sbjct: 494 EIERLGQDL 502 >6ENZ-A nrPDB Length = 530 Score = 455 bits (1170), Expect = e-128, Method: Composition-based stats. Identities = 113/493 (22%), Positives = 207/493 (41%), Gaps = 44/493 (8%) Query: 4 SEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKI 63 R +E+V + E + Q P LR L+ ++ + ++ + + Sbjct: 60 EACRLIMEEVVLKATDVNEKVCEWQP-----PEQLRQLLDLEMRDTGESQDKLLKLCQDV 114 Query: 64 IMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLG 123 I V H P FF Y ++ A ++ A+ +++ SP +E + L Sbjct: 115 IHFSVKTNH-PRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAV---LK 170 Query: 124 KMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI--ME 181 KM+E EG G+ S + + A+ AR + P++ + + + Sbjct: 171 KMIECVGW------KEGDGIFNPGGSVSNMCAMNLARYR-------HCPDIKEKGLSGLP 217 Query: 182 KLVAYSSDQAHSSVERAGLIGGV---KLKAIPSDGNFAMRASALQEALERDKAAGLIPFF 238 +L+ ++S + H S+++A G+ + + +DG M L++ + + + G +PF Sbjct: 218 RLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFL 277 Query: 239 MVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFN 298 + AT GTT +FD L E+ +C + +WLHVDA++ GSA + + R LL+G+ ADS Sbjct: 278 VCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVA 337 Query: 299 FNPHKWLLVNFDCSAMWVKKRTD-LTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRF 357 +NPHK L+ CSA+ VK ++D L + TYL + + D I RR Sbjct: 338 WNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATYLFQQDKFYDVSYDTGDKSIQCSRRP 397 Query: 358 RSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCF------ 411 + K W ++ G GL+ + + LS +++ F++ +E VCF Sbjct: 398 DAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPS 457 Query: 412 --RLKGSNKVNEALL-------QRINSAKKIHLVPCHLRDKF-VLRFAICSRTVESAHVQ 461 ++ + L +++ + L R K R + S V + Sbjct: 458 LREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMD 517 Query: 462 RAWEHIKELAADV 474 + I L D+ Sbjct: 518 FLLDEIDSLGRDM 530 >2OKK-A nrPDB Length = 497 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 108/460 (23%), Positives = 192/460 (41%), Gaps = 34/460 (7%) Query: 35 PGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADML 94 P L +P E+I+ + + + H P +F T + AD L Sbjct: 51 PNELLQEYNWELADQPQNLEEILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWL 109 Query: 95 CGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLV 154 F++ +P LE V + + +++ P G G G+ + + + Sbjct: 110 TSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWP-------GGSGDGIFSPGGAISNMY 162 Query: 155 ALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGL---IGGVKLKAIPS 211 A++ AR K+ ++ A + +L+A++S+ +H S+++ IG + I Sbjct: 163 AMMIARFKMFPEVKEKG-----MAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKC 217 Query: 212 DGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVD 271 D M S L+ + K G +PF + AT GTT +FD LL V IC K IW+HVD Sbjct: 218 DERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVD 277 Query: 272 AAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPT 331 AA+ G + + + L+GVE A+S +NPHK + V CSA+ V++ + ++ + Sbjct: 278 AAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHAS 337 Query: 332 YLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESL 391 YL + L D + GR K+W ++R G G +A++ K ++L+ ++ Sbjct: 338 YLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNI 397 Query: 392 VRQDPRFEICVE--VILGLVCF--------RLKGSNKVNEALLQ-------RINSAKKIH 434 ++ +E+ + VCF L+ + + L + R+ Sbjct: 398 IKNREGYEMVFDGKPQHTNVCFWYIPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTM 457 Query: 435 LVPCHLRDKF-VLRFAICSRTVESAHVQRAWEHIKELAAD 473 + L DK R I + + E I+ L D Sbjct: 458 VSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQD 497 >2JIS-A nrPDB Length = 515 Score = 446 bits (1146), Expect = e-125, Method: Composition-based stats. Identities = 96/463 (20%), Positives = 190/463 (41%), Gaps = 39/463 (8%) Query: 34 EPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADM 93 EP L+ L+ + ++ + I+ +I V H P FF + A+ + Sbjct: 70 EPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGH-PRFFNQLFSGLDPHALAGRI 128 Query: 94 LCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATL 153 + ++ +++ +P +E ++ L ++ G G+ S + + Sbjct: 129 ITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGW---------SSGDGIFCPGGSISNM 179 Query: 154 VALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGLIGGVK---LKA 208 A+ AR + P+ Q + + L ++S + H S+++ G+ ++ Sbjct: 180 YAVNLARYQ-------RYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRV 232 Query: 209 IPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWL 268 + +D M L+ + +A G +PF + AT GTT +FD L + +C + +WL Sbjct: 233 VKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 292 Query: 269 HVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD-LTGAFR 327 HVDAA+ GS + RHLL+G++ ADS +NPHK L CSA+ ++ ++ L Sbjct: 293 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHG 352 Query: 328 LDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHE 387 +YL + + D + GRR LK+W +++ G +GL+ I + L+ Sbjct: 353 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARY 412 Query: 388 FESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEA---------------LLQRINSAKK 432 +++ FE+ +E VCF + + L +R+ Sbjct: 413 LVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGS 472 Query: 433 IHLVPCHLRDK-FVLRFAICSRTVESAHVQRAWEHIKELAADV 474 + + + R + + + A + ++ L D+ Sbjct: 473 MMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL 515 >2QMA-A nrPDB Length = 497 Score = 446 bits (1146), Expect = e-125, Method: Composition-based stats. Identities = 115/484 (23%), Positives = 208/484 (42%), Gaps = 24/484 (4%) Query: 1 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDT-FEDIIND 59 + ++EF M + E + Y ++P L I A + + +I+D Sbjct: 29 LGSAEFASVMSHTTSAMKSVFEQVNA--PYSGMDPKALEDAINAVDLDNKNAPLKSVIDD 86 Query: 60 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM 119 V +++ P A+ T PA+ A+ + A+ SW + + T +E ++ Sbjct: 87 VAELVAKNAIFTQHPDCIAHLHTPPLMPAVAAEAMIAALNQSMDSWDQASSATYVEQKVV 146 Query: 120 DWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAAS-PELTQAA 178 +WL K L+EK G+ +++ + L+ AR + +L S +L Sbjct: 147 NWL-----CDKYDLSEK---ADGIFTSGGTQSNQMGLMLARDWIADKLSGHSIQKLGLPD 198 Query: 179 IMEKLVAYSSDQAHSSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLI 235 +KL S ++H +V+++ G+ KA+ ++ + M + L E + + KA GLI Sbjct: 199 YADKLRIVCSKKSHFTVQKSASWMGLGEKAVMTVDANADGTMDITKLDEVIAQAKAEGLI 258 Query: 236 PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFAD 295 PF +V T GTT + D+L + + K D+W+HVD AY G A I + L GVE A Sbjct: 259 PFAIVGTAGTTDHGAIDDLDFIADMAVKHDMWMHVDGAYGG-ALILSSHKSRLKGVERAH 317 Query: 296 SFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGR 355 S + + HK C A+ V +++ YL H + + D I + Sbjct: 318 SISVDFHKLFYQTISCGALLVNDKSNFKFLLH-HADYLNREHDELPNLVD---KSIATTK 373 Query: 356 RFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 RF +LK++ + G K L + + E ++R + +FE+ E L V FR Sbjct: 374 RFDALKVFMTMQNVGPKALGDMYDHLLAQTLEVADMIRTNDQFELLAEPSLSTVLFRATH 433 Query: 416 S----NKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELA 471 +++N+AL + L + K L+F I + + ++ + I LA Sbjct: 434 ETADLDELNKALRLEALTRGIAVLGETIVDGKTALKFTILNPCLTTSDFESLLSKINMLA 493 Query: 472 ADVL 475 +++ Sbjct: 494 VELV 497 >4OBV-D nrPDB Length = 490 Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 122/487 (25%), Positives = 213/487 (43%), Gaps = 36/487 (7%) Query: 1 MNASEFRRRGKEMV-DYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIIND 59 +N+++ K V D+ A E I + V + + + P++ +++++ Sbjct: 20 LNSTQLEEAIKSFVHDFCAEKHE-IHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSE 78 Query: 60 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM 119 + + + P FF++ P +S + L D++ A +P +E ++ Sbjct: 79 MMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVL 138 Query: 120 DWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179 WL K + + GGV S A + AL AAR + + Sbjct: 139 KWLAKQVGFTE--------NPGGVFVSGGSMANITALTAARDNKLTDIN----------- 179 Query: 180 MEKLVAYSSDQAHSSVERAGLIGGV---KLKAIPSDGNFAMRASALQEALERDKAAGLIP 236 + AY SDQ HSSV + I G+ +++ IP++ +F M + L+EA+E DK +G IP Sbjct: 180 LHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIP 239 Query: 237 FFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADS 296 F ++ T GTT S D L E+ +C K D+W H+D AY S + P+++ LL G ADS Sbjct: 240 FVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADS 299 Query: 297 FNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQI--PLG 354 +++ HKWL + C+ + VK +L +F ++P YLK D + W I L Sbjct: 300 ISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLKDLENDID---NVNTWDIGMELT 356 Query: 355 RRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRL- 413 R R LK+W ++ G + + I QL+ E + +EI + ++ FR Sbjct: 357 RPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYA 416 Query: 414 ------KGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHI 467 + + +NE + RI + + L K VLR +Q + + Sbjct: 417 PKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLL 476 Query: 468 KELAADV 474 + ++ Sbjct: 477 DQYGREI 483 >4RIT-B nrPDB Length = 486 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 125/490 (25%), Positives = 210/490 (42%), Gaps = 36/490 (7%) Query: 2 NASEFRRRGKEMVDYMANYMEGIEGRQVYPDVE--PGYLRPLIPAAAPQEPDTFEDIIND 59 N +E R +++VD + + G R P+ PG + IP AA E + I + Sbjct: 21 NRNEVERLVQQVVDLILAKLTGAAERPPMPETVDLPGPI--TIPEAAATEATLLQAIRDM 78 Query: 60 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM 119 V+ + P +P + + + A+L D++ A+ S SP+ + LET+++ Sbjct: 79 VDGSMNPA-----NPGYIGHMDPMPATMAILGDLVAAAVNNNMLSLEMSPSFSRLETLLL 133 Query: 120 DWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179 + + L + + GGV+ S A L AL AR ++ + Sbjct: 134 RAIAGLFGLGE--------QAGGVLTSGGSLANLQALAVARNVAFDSVEPGI-----TGL 180 Query: 180 MEKLVAYSSDQAHSSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLIP 236 ++ V ++S+ AH+S+++A ++ G+ A+ + + M L+ +++ + AG P Sbjct: 181 AQRPVIFASEAAHTSLQKAAMLLGLGTAAVIPVRATADSRMDPEDLRARIDQARGAGQHP 240 Query: 237 FFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADS 296 F +VAT GTTT + D L E+G I + +W HVDAAY G+ R L G+E ADS Sbjct: 241 FCVVATAGTTTTGNIDPLAEIGAIAREHGLWFHVDAAYGGALVFSERHRWRLAGIEQADS 300 Query: 297 FNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRR 356 FNP KWL V C+ + + L AFR+ Y++ + L + R Sbjct: 301 ITFNPQKWLYVAKTCAMVLFRDAGVLERAFRIPAPYMRATDGFINL----GEIGVQGTRH 356 Query: 357 FRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGS 416 +K+W + G +G I +L+ VRQ P + E+ +VCFR + Sbjct: 357 ADVVKLWLTLQHIGQQGYARLIDDGYRLAERVVEGVRQRPFLRLAGEIDTNIVCFRGEPD 416 Query: 417 -------NKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKE 469 + N AL + KI L R LR + + A + ++ I Sbjct: 417 WLPAERWDDWNAALQALLLREGKIFLSLPVYRGGRWLRAVLLNPYTTDAVIDAMFKQIDR 476 Query: 470 LAADVLRAER 479 A ER Sbjct: 477 FAGRERGQER 486 >3F9T-A nrPDB Length = 397 Score = 274 bits (700), Expect = 7e-74, Method: Composition-based stats. Identities = 71/359 (19%), Positives = 139/359 (38%), Gaps = 43/359 (11%) Query: 124 KMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKL 183 K + L + LN K + G I +EA L+AL + + + + I+ + Sbjct: 73 KAVALLGSLLNNK--DAYGHIVSGGTEANLMALRCIKNIWREKRRKGLSKNEHPKIIVPI 130 Query: 184 VAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATL 243 A H S E+ + ++ P ++ + +++A+E G+I Sbjct: 131 TA------HFSFEKGREMMDLEYIYAPIKEDYTIDEKFVKDAVEDYDVDGII-----GIA 179 Query: 244 GTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEF-------ADS 296 GTT + DN+ E+ I + +I++HVDAA+ G + ++ GV + DS Sbjct: 180 GTTELGTIDNIEELSKIAKENNIYIHVDAAFGGLVIPFLDDKYKKKGVNYKFDFSLGVDS 239 Query: 297 FNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRR 356 +PHK + K Y ++ D+ +T+ R I LG R Sbjct: 240 ITIDPHKMGHCPIPSGGILFKD-----------IGYKRYLDVDAPYLTETRQATI-LGTR 287 Query: 357 --FRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLK 414 F + V R G +G + + + ++ + ++++ F+ +E IL +V + Sbjct: 288 VGFGGACTYAVLRYLGREGQRKIVNECMENTLYLYKKLKEN-NFKPVIEPILNIVAIEDE 346 Query: 415 GSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAAD 473 +V + L R + + C LR + ++ H+ E + + D Sbjct: 347 DYKEVCKKLRDR---GIYVSVCNCV----KALRIVVM-PHIKREHIDNFIEILNSIKRD 397 >5HSI-A nrPDB Length = 634 Score = 127 bits (320), Expect = 8e-30, Method: Composition-based stats. Identities = 77/471 (16%), Positives = 154/471 (32%), Gaps = 107/471 (22%) Query: 53 FEDIINDVEKIIMPGVTHWHSP-YFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPAC 111 + +++ + + I WHS ++ + + + PA+LA ++ +SPA Sbjct: 71 MKTVLDQLSERIRTESVPWHSAGRYWGHMNSETLMPALLAYNYAMLWNGNNVAYESSPAT 130 Query: 112 TELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKV-------- 163 +++E + +++ G G I S A L L AR Sbjct: 131 SQMEEEVGQEFARLMGY---------DYGWGHIVADGSLANLEGLWYARNIKSLPFAMKE 181 Query: 164 -------------------------IHRLQAASPELTQAAI-----MEKLVAYSSDQA-H 192 + + E+ + + +++L + Q H Sbjct: 182 VNPELVAGKSDWELLNMPTKEIMDLLENAGSQIDEVKKRSARSGKNLQRLGKWLVPQTKH 241 Query: 193 SSVERAGLIGGVKLKAI---PSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCC 249 S +A I G+ L + P D N+ M AL+ + + A +V G+T Sbjct: 242 YSWMKAADIIGIGLDQVVPVPIDSNYRMDIQALESIIRKYAAEKTPILGVVGVAGSTEEG 301 Query: 250 SFDNLLEVGPI---CNKEDIW--LHVDAAYAGSA------------------------FI 280 + D + ++ + KE I+ LHVDAAY G A + Sbjct: 302 AVDGIDKIVALRQKLQKEGIYFYLHVDAAYGGYARALFLDEDDQFIPYKNLQKVHAENHV 361 Query: 281 CPEFRHLLN--------GVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTY 332 E + + + A+S +PHK V + + ++ + TY Sbjct: 362 FTEDKEYIKPEVYAAYKAFDQAESITIDPHKMGYVPYSAGGIVIQDIR-MRDTISYFATY 420 Query: 333 LKHSHQDSGLITDYRHWQIPLGRRFR--SLKMWFVFRM--YGVKGLQAYIRKHVQLSHEF 388 + D + I G + + +W V G ++ +H + Sbjct: 421 VFEKGADIPALLG---AYILEGSKAGATAASVWAAHHTLPLNVTGYGKLEGASIEGAHRY 477 Query: 389 ESLVRQDPRFEI---------CVEVILGLVCFRLKGSNKVNEALLQRINSA 430 ++ + +FE+ + +V + LK + + R+N A Sbjct: 478 YDFLK-NLKFEVAGKRISVHPLISPDFNMVDYVLKEDGNDDLIEMNRLNHA 527 >5K1R-A nrPDB Length = 480 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 73/422 (17%), Positives = 135/422 (31%), Gaps = 56/422 (13%) Query: 22 EGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFP 81 EG+ Y E G L P+ E ++ ++ + + W S Sbjct: 5 EGVRQLYPYA-AEFGALHEF-----PERGMPRERLLEELRSMAVREDRKWESGRCSGTMY 58 Query: 82 TAS-SYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEG 140 + A L + P+ +E+ ++ +L ++ A Sbjct: 59 CGDHEHYAFLNEAYGLFSHVNALQRDLCPSMNRMESEIVAMTVALLHGEAVQRHDGAHRA 118 Query: 141 GGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGL 200 G + +E+ L A LA R K P + A AH + +A Sbjct: 119 CGALSLGGTESILNATLAYREKARAERGIERPRMIWPA-----------SAHPAFRKAAH 167 Query: 201 IGGVKLKAIPSDG-NFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGP 259 + G + P D + A +++A++ + +V + + D + + Sbjct: 168 LFGFDVTVAPIDPVTMQVDADFVRDAVDANT------VMLVGSACNYPYGTIDPIGALSA 221 Query: 260 ICNKEDIWLHVDAAYAGSAFI---------CPEFRHLLNGVEFADSFNFNPHKWLLVNFD 310 I ++D+WLHVD G P F L GV S + + HK+ Sbjct: 222 IAVEKDVWLHVDGCLGGWMLPWGEALGYPDIPAFDFRLPGVT---SISADTHKFGYGPKG 278 Query: 311 CSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL--KMWFVFRM 368 S + + + + L ++ + GL G R L W R Sbjct: 279 GSVLAWRDASFRRHQYFLMTDWVGGVYGSPGL----------TGSRSGGLIAATWAALRS 328 Query: 369 YGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSN----KVNEALL 424 G +G A + + + + ++ VR P + + CF VN+ + Sbjct: 329 LGREGYLARAKAIFETAFDMQAAVRAIPELRVLGKPTF---CFAFTSDAFDIYHVNDFMR 385 Query: 425 QR 426 QR Sbjct: 386 QR 387 >3MAF-B nrPDB Length = 518 Score = 112 bits (281), Expect = 3e-25, Method: Composition-based stats. Identities = 58/363 (15%), Positives = 117/363 (32%), Gaps = 46/363 (12%) Query: 78 AYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKA 137 A + + A L ++ P+ + E ++ ML A Sbjct: 108 AVYHGDEHHIAFLNEVYALQSQSNPLHPDLWPSTAKFEAEVVAMTAHMLGGDAA-----G 162 Query: 138 GEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVER 197 G G + +E+ L+A+ R +PE AH++ ++ Sbjct: 163 GTVCGTVTSGGTESLLLAMKTYRDWARATKGITAPEAVVPV-----------SAHAAFDK 211 Query: 198 AGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEV 257 A G+KL P D ++ +A++EA+ + + + D + E+ Sbjct: 212 AAQYFGIKLVRTPLDADYRADVAAMREAITPNT------VVVAGSAPGYPHGVVDPIPEI 265 Query: 258 GPICNKEDIWLHVDAAYAGSAF--------ICPEFRHLLNGVEFADSFNFNPHKWLLVNF 309 + + I HVDA G P F L GV S + + HK+ Sbjct: 266 AALAAEHGIGCHVDACLGGFILPWAERLGYPVPPFDFRLEGVT---SVSADTHKYGYGAK 322 Query: 310 DCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMY 369 S + ++ L + + + S R + W Sbjct: 323 GTSVILYRRPDLLHYQYFIAADW-PGGLYFSPTFAGSRPGALSAT-------AWAAMLSL 374 Query: 370 GVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNE-ALLQRIN 428 G +G R+ +Q + ++ VR P +I + + + S+++N +++ + Sbjct: 375 GEEGYLDATRRILQAADRLKAGVRAIPSLKILGDPLWVI----AVASDELNIYQVMEEMA 430 Query: 429 SAK 431 Sbjct: 431 GRG 433 >3HBX-A nrPDB Length = 502 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 90/470 (19%), Positives = 166/470 (35%), Gaps = 70/470 (14%) Query: 37 YLRPLIPA-AAPQEPDTFEDIINDVEKIIMPG----------VTHWHSPYFFAYFPTASS 85 Y+R +P P+ E + +M VT W P Sbjct: 22 YVRTSLPRFKMPENSIPKEAAYQIINDELMLDGNPRLNLASFVTTWMEPEC--------- 72 Query: 86 YPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQ 145 ++ +I P TEL+ ++ + + P E+A GV Sbjct: 73 -----DKLIMSSINKNYVDMDEYPVTTELQNRCVNMIAHLFNAP----LEEAETAVGVGT 123 Query: 146 GSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVK 205 +SEA ++A LA + K ++ +A + + I+ + E+ V+ Sbjct: 124 VGSSEAIMLAGLAFKRKWQNKRKAEGKPVDKPNIV------TGANVQVCWEKFARYFEVE 177 Query: 206 LKAIP-SDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC--- 261 LK + S+G + M + ++ + + A LG+T F+++ + + Sbjct: 178 LKEVKLSEGYYVMDPQQAVDMVDENT------ICVAAILGSTLNGEFEDVKLLNDLLVEK 231 Query: 262 NKEDIW---LHVDAAYAG--SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWV 316 NKE W +HVDAA G + F+ PE + S N + HK+ LV + Sbjct: 232 NKETGWDTPIHVDAASGGFIAPFLYPELEWDFR-LPLVKSINVSGHKYGLVYAGIGWVIW 290 Query: 317 KKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQA 376 + + DL YL L Q+ + ++ G +G + Sbjct: 291 RNKEDLPEELIFHINYLGADQPTFTLNFSKGSSQV--------IAQYYQLIRLGHEGYRN 342 Query: 377 YIRKHVQLSHEFESLVRQDPRFEICVEVI-LGLVCFRLKGSNKVNE-ALLQRINSAKKI- 433 + + + + RF I + + LV F LK S+ E + + I Sbjct: 343 VMENCRENMIVLREGLEKTERFNIVSKDEGVPLVAFSLKDSSCHTEFEISDMLRRYGWIV 402 Query: 434 --HLVPCHLRDKFVLRFAI---CSRTVESA---HVQRAWEHIKELAADVL 475 + +P + + VLR I SRT+ +++ + EL + V+ Sbjct: 403 PAYTMPPNAQHITVLRVVIREDFSRTLAERLVIDIEKVMRELDELPSRVI 452 >4Q6R-A nrPDB Length = 511 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 65/417 (15%), Positives = 130/417 (31%), Gaps = 65/417 (15%) Query: 10 GKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVT 69 G+++ D + + I + V+ Y++ A P + + ++ +++ Sbjct: 28 GRKIQDKLNKTKDDISKNMSFLKVDKEYVK-----ALPSQGLSSSAVLEKLKEYSSMDA- 81 Query: 70 HWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSW------AASPACTELETVMMDWLG 123 W + L ++L A G F+W P ++E ++ Sbjct: 82 FWQEGRASGTVYSGEEK---LTELLVKAYGD--FAWSNPLHPDIFPGLRKIEAEIVR--- 133 Query: 124 KMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKL 183 L + G + +E+ L+A A R + + I+ Sbjct: 134 -----IACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEK------GIKTPEIVAP- 181 Query: 184 VAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATL 243 AH++ +A G+K+ +P + A++ A+ R+ A + +T Sbjct: 182 -----QSAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTA-----MLVCSTP 231 Query: 244 GTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPE---------FRHLLNGVEFA 294 D + EV + K I LHVDA G + E F + GV Sbjct: 232 -QFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVT-- 288 Query: 295 DSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLG 354 S + + HK+ S + + Y D Y I Sbjct: 289 -SISADTHKYGYAPKGSSLVLYSDKKY--------RNYQFFVDTDWQGGI-YASPTIAGS 338 Query: 355 RRFR-SLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVC 410 R S W +G G ++ ++ + +S + + L ++ Sbjct: 339 RPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIA 395 >3MC6-C nrPDB Length = 497 Score = 85.5 bits (210), Expect = 5e-17, Method: Composition-based stats. Identities = 63/399 (15%), Positives = 137/399 (34%), Gaps = 50/399 (12%) Query: 46 APQEPDTFEDIINDVEKI--IMPGVTHWHSPYFFAYFPTASSYP---AMLADMLCGAIGC 100 P +D+I ++ K+ ++P A + + + C A Sbjct: 38 LPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVA--- 94 Query: 101 IGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAAR 160 PA ++E+ ++ + +M P GG +E+ L+A L+A+ Sbjct: 95 NQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGG-------TESLLLACLSAK 147 Query: 161 TKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSD-GNFAMRA 219 +H +T+ I+ + A H+ ++A G+KL+ + D + + Sbjct: 148 MYALHHRG-----ITEPEIIAPVTA------HAGFDKAAYYFGMKLRHVELDPTTYQVDL 196 Query: 220 SALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAF 279 +++ + ++ +V + D++ +G I K + LHVD+ Sbjct: 197 GKVKKFINKNT------VLLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIV 250 Query: 280 ICPEFRHLLN------GVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYL 333 E N V S + + HK+ S + + + ++P + Sbjct: 251 SFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWT 310 Query: 334 KHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVR 393 + S + R I +G W G G ++ V + +F+ ++ Sbjct: 311 GGLY-GSPTLAGSRPGAIVVG-------CWATMVNMGENGYIESCQEIVGAAMKFKKYIQ 362 Query: 394 QD-PRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAK 431 ++ P +I ++ F K N L R++ Sbjct: 363 ENIPDLDIMGNPRYSVISFSSKTLNI--HELSDRLSKKG 399 >5GP4-C nrPDB Length = 468 Score = 82.0 bits (201), Expect = 5e-16, Method: Composition-based stats. Identities = 65/438 (14%), Positives = 150/438 (34%), Gaps = 63/438 (14%) Query: 33 VEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLAD 92 +EP L+ E ++ ++ + + P + Sbjct: 39 LEPREADRLVRDQLLDEGNSRLNLATFCQTYMEPEAV----------------------E 76 Query: 93 MLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEAT 152 ++ + + P E+E ++ + + P+A G +SEA Sbjct: 77 LMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFT------GTSTIGSSEAC 130 Query: 153 LVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSD 212 ++A LA + R +A +LT + S E+ + + + +P D Sbjct: 131 MLAGLAMKFAWRKRAKANGLDLT----AHQPNIVISAGYQVCWEKFCVYWDIDMHVVPMD 186 Query: 213 GNF-AMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKED------ 265 + ++ + + ++ +V +G T +D+L + + + + Sbjct: 187 DDHMSLNVDHVLDYVDDYT------IGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFP 240 Query: 266 IWLHVDAAYAG--SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLT 323 +++HVDAA G + FI PE + + S N + HK+ LV + + + L Sbjct: 241 VYIHVDAASGGFYTPFIEPELKWDFR-LNNVISINASGHKYGLVYPGVGWVIWRDQQYLP 299 Query: 324 GAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQ 383 +YL + + ++ H L + ++ F +G G + K Sbjct: 300 KELVFKVSYL--GGELPTMAINFSHSASQL------IGQYYNFIRFGFDGYREIQEKTHD 351 Query: 384 LSHEFESLVRQDPRFEICVE-VILGLVCFRLKGSNKVN---EALLQRINSAKK---IHLV 436 ++ + + F + + L L+C+ L + L R+ + + Sbjct: 352 VARYLAKSLTKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPL 411 Query: 437 PCHLRDKFVLRFAICSRT 454 P ++ D+ + R + + Sbjct: 412 PKNMTDRVIQRIVVRADF 429 >4W8I-A nrPDB Length = 551 Score = 80.1 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 50/335 (14%), Positives = 109/335 (32%), Gaps = 49/335 (14%) Query: 95 CGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLV 154 + W P ++ ++ W L + EG G++ + + + Sbjct: 124 TALTNPLHDKW---PRINAMQAEVIRWC--------QNLFHGSKEGYGLLTHGGTTSIIE 172 Query: 155 ALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGN 214 A+ A + ++A + + I+ + AH++ ++A + G L +P D Sbjct: 173 AMAA------YVIRARAKGIDYPEIVVP------ETAHAAFKKAAELTGAILITVPVDKK 220 Query: 215 -FAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAA 273 A+ + + + R+ A MV + + D + E+G + K+++ HVDA Sbjct: 221 TGAVNPNVMSSYITRNTA------VMVGSAPSFMNGIHDPISELGQLAKKKNVPFHVDAC 274 Query: 274 YAG--SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPT 331 G +AF+ + V S + + HK+ S + + + Sbjct: 275 LGGFLTAFLDTSSEPMDFRVPGVTSISADLHKYGCCPKGTSVCLFSEDSPALSVYAA--- 331 Query: 332 YLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQL----SHE 387 + R +++ YG Q + ++L E Sbjct: 332 --LNWSGGLYATPGILDGS---TSGARVAEVYATLSYYGKNKYQEIAKSIIRLRNAIQKE 386 Query: 388 FESLVRQ-----DPRFEICVEVILGLVCFRLKGSN 417 +LV + + ++ FR N Sbjct: 387 LTALVEEGNGLTSEDIYVYGNPQWSILGFRSNTCN 421 >2DGM-A nrPDB Length = 466 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 55/299 (18%), Positives = 102/299 (34%), Gaps = 47/299 (15%) Query: 136 KAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSV 195 K G+ G +SEA ++ +A + + R++AA + ++ V Sbjct: 114 KNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQIC-------W 166 Query: 196 ERAGLIGGVKLKAIPSDGNFAMRASAL----QEALERDKAA--GLIPFFMVATLGTTTCC 249 + V+L+ IP MR L + +E G++P T G T Sbjct: 167 HKFARYWDVELREIP------MRPGQLFMDPKRMIEACDENTIGVVP-----TFGVTYTG 215 Query: 250 SFDNLLEVGPICNKE------DIWLHVDAAYAGSA--FICPEFRHLLNGVEFADSFNFNP 301 +++ + +K DI +H+DAA G F+ P+ + S + + Sbjct: 216 NYEFPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFR-LPRVKSISASG 274 Query: 302 HKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFR-SL 360 HK+ L C + + L + YL + I R + Sbjct: 275 HKFGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQ---------IGTFAINFSRPAGQVI 325 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEIC--VEVILGL--VCFRLKG 415 ++ F G +G Q++ + + +E G+ VCF+LK Sbjct: 326 AQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKD 384 >5WT2-A nrPDB Length = 401 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 29/188 (15%), Positives = 59/188 (31%), Gaps = 29/188 (15%) Query: 143 VIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIG 202 +I A+E+ L + ++ H +V Sbjct: 68 IITSCATESNNWVLKGVYFDECLKKGKNH-------------IVTTVAEHPAVRSTCNFL 114 Query: 203 ---GVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGP 259 GV++ +P + + ++ A ++EA+ A + + E+G Sbjct: 115 ESLGVEVTYLPINEHGSITAEQVREAITEKTA------LVSVMWANNETGLIFPIEEIGA 168 Query: 260 ICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKR 319 IC ++ + H DA A + AD +F+ HK ++++ Sbjct: 169 ICKEKGVLFHTDAVQAIGKIPVDVLKA------NADFLSFSAHK-FHGPKGIGGLYIRSG 221 Query: 320 TDLTGAFR 327 LT F Sbjct: 222 VGLTPLFH 229 >3LVM-A nrPDB Length = 423 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 68/433 (15%), Positives = 127/433 (29%), Gaps = 79/433 (18%) Query: 65 MPGVTHWHS-PYFFAYFPTASSYPAMLADML----------CGAIGCIGFSWAASPACTE 113 M GV P + Y T P + M+ A F W A Sbjct: 13 MYGVYRAMKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQA------ 66 Query: 114 LETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPE 173 E + ++ +L A E V A+E+ +A+ A + + Sbjct: 67 -EEAVDIARNQIADLVGADPREI------VFTSGATESDNLAIKGAANFYQKKGKH---- 115 Query: 174 LTQAAIMEKLVAYSSDQAHSSVERAGLIG---GVKLKAIPSDGNFAMRASALQEALERDK 230 +S H +V G ++ + N + L+ A+ D Sbjct: 116 -----------IITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDT 164 Query: 231 AAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNG 290 + ++ +G +C I HVDA + P L Sbjct: 165 ------ILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKL--PIDLSQLK- 215 Query: 291 VEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQ 350 D +F+ HK + A++V+++ + ++ + + L H Sbjct: 216 ---VDLMSFSGHK-IYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPV---HQI 268 Query: 351 IPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVC 410 + +G +R K M ++GL+ + ++ E + E IL V Sbjct: 269 VGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVY----LNGDLEHGAPNILN-VS 323 Query: 411 FRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVL--------------RFAICSRTVE 456 F + AL S+ L +VL RF++ R Sbjct: 324 FNYVEGESLIMALKDLAVSSGSA-CTSASLEPSYVLRALGLNDELAHSSIRFSLG-RFTT 381 Query: 457 SAHVQRAWEHIKE 469 + E +++ Sbjct: 382 EEEIDYTIELVRK 394 >1SVV-A nrPDB Length = 359 Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 29/166 (17%), Positives = 55/166 (33%), Gaps = 29/166 (17%) Query: 123 GKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEK 182 K L L + + ++ L+A A + Sbjct: 52 AKAARLIGELL--ERPDADVHFISGGTQTNLIACSLA--------------------LRP 89 Query: 183 LVAYSSDQ-AHSSVERAGLI--GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFM 239 A + Q H S G I G K+ P + +R + ++ AL +++ ++ + Sbjct: 90 WEAVIATQLGHISTHETGAIEATGHKVVTAPC-PDGKLRVADIESALHENRSEHMVIPKL 148 Query: 240 VATLGTTTCCSF---DNLLEVGPICNKEDIWLHVDAAYAGSAFICP 282 V TT + L ++ C + ++L +D A SA P Sbjct: 149 VYISNTTEVGTQYTKQELEDISASCKEHGLYLFLDGARLASALSSP 194 >1WYV-B nrPDB Length = 474 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 52/284 (18%), Positives = 90/284 (31%), Gaps = 36/284 (12%) Query: 122 LGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIME 181 L M EL + + + + + L +L R + + Sbjct: 106 LRLMWELGEYLKALTGMDAITLEPAAGAHGELTGILIIR----------AYHEDRGEGRT 155 Query: 182 KLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVA 241 + V D AH S + G +++ IPS + AL+ L AA M+ Sbjct: 156 RRVVLVPDSAHGSNPATASMAGYQVREIPSGPEGEVDLEALKRELGPHVAA-----LMLT 210 Query: 242 TLGTTTCCSFD-NLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300 T F+ +LE+ +C + + L+ D A + G D + N Sbjct: 211 NPNT--LGLFERRILEISRLCKEAGVQLYYDGANLNAIM-----GWARPGDMGFDVVHLN 263 Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLK---HSHQDSGLITDY-RHWQIPLGRR 356 HK F + G YL + G D+ R I R Sbjct: 264 LHK----TFTVPHGGGGPGSGPVGVKAHLAPYLPVPLVERGEEGFYLDFDRPKSIGRVRS 319 Query: 357 FRS-----LKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQD 395 F ++ W R G++GL+ V + + L+++ Sbjct: 320 FYGNFLALVRAWAYIRTLGLEGLKKAAALAVLNARYLKELLKEK 363 >2E7J-A nrPDB Length = 371 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 52/133 (39%), Gaps = 9/133 (6%) Query: 189 DQAHSSVERAGLIGGVKLKAIPSDG--NFAMRASALQEALERDKAAGLIPFFMVATLGTT 246 + H S A G+ + +P ++A+ + +E K G + ++ T Sbjct: 100 ENCHYSSYVAAERAGLNIALVPKTDYPDYAITPENFAQTIEETKKRGEVVLALI-TYPDG 158 Query: 247 TCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLL 306 + ++ ++ +C++ D+ L V+ AYA L + AD + HK + Sbjct: 159 NYGNLPDVKKIAKVCSEYDVPLLVNGAYAIGRMPVS-----LKEIG-ADFIVGSGHKSMA 212 Query: 307 VNFDCSAMWVKKR 319 + M +K+ Sbjct: 213 ASGPIGVMGMKEE 225 >5WGB-A nrPDB Length = 426 Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 38/272 (13%), Positives = 85/272 (31%), Gaps = 55/272 (20%) Query: 51 DTFEDIINDVEKI--IMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAAS 108 + + DV+ + P V PY Y+ S + W + Sbjct: 23 EMLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHS-------------RTHAYGWESE 69 Query: 109 PACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALL-AARTKVIHRL 167 A + +G A + A+E+ +A+ AR + Sbjct: 70 AAMERARQQVASLIG-------------ADPREIIFTSGATESNNIAIKGVARFYRSRKK 116 Query: 168 QAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALE 227 + + +++ + ++ G ++ +P + + L+ A++ Sbjct: 117 HLITTQTEHKCVLDSCRSLEAE-------------GFQVTYLPVQKSGIIDLKELEAAIQ 163 Query: 228 RDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHL 287 D + L+ V + E+G IC+ ++ H DAA A Sbjct: 164 PDTS--LVSVMTVNN----EIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMK 217 Query: 288 LNGVEFADSFNFNPHKWLLVNFDCSAMWVKKR 319 + D + + HK + A+++++R Sbjct: 218 I------DLMSISGHK-IYGPKGVGAIYIRRR 242 >5XT5-A nrPDB Length = 419 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 41/289 (14%), Positives = 81/289 (28%), Gaps = 53/289 (18%) Query: 143 VIQGSASEA-TLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLI 201 + + + +VAL AR + + + A + ++A Sbjct: 90 IFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPW------------QQAVKA 137 Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 G LK IP + + ++E + + + + + + + + E+ I Sbjct: 138 TGATLKYIPLQEDGTISLEDVRETVTSNTK------IVAVSHVSNVLGTVNPIKEMAKIA 191 Query: 262 NKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADS--FNFNPHKWLLVNFDCSAMWVKKR 319 + + VD A H+ V+ D F + HK + K+ Sbjct: 192 HDNGAVIVVDGA--------QSTPHMKIDVQDLDCDFFALSSHKM--CGPTGVGVLYGKK 241 Query: 320 TDLTGAFRLDPTYLKHSHQDSGLITDYRH----------WQIPLGRRF--RSLKMWFVFR 367 L + G + D+ W+ G ++ + Sbjct: 242 ALLENM---------EPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAID 292 Query: 368 MYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVI-LGLVCFRLKG 415 GL R +L+ RQ + GLV F L Sbjct: 293 FLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDD 341 >5V1X-E nrPDB Length = 501 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 29/200 (14%), Positives = 66/200 (33%), Gaps = 26/200 (13%) Query: 210 PSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLH 269 P++ + + +A ++A+++ + G P V + ++ ++ IC +E+I Sbjct: 169 PAEDDDVV--AAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISC 226 Query: 270 VDAAYAGSAF---ICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMW--VKKRTDLTG 324 VD A I L + N HKWL C+ + V+ + + Sbjct: 227 VDGAQGIGMVDLKITETDPDFL--------IS-NCHKWLFTPRGCAVFYVPVRNQHLIRS 277 Query: 325 AFRLDPTYLKHSHQDSGLITDYRHWQIPLG----------RRFRSLKMWFVFRMYGVKGL 374 ++ + + + F +K +R + G Sbjct: 278 TLPTSHGFVPQVGNRFNPLVPAGNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGE 337 Query: 375 QAYIRKHVQLSHEFESLVRQ 394 + + +L+ E V + Sbjct: 338 ERIMEYMTKLAREGGQKVAE 357 >3WGB-A nrPDB Length = 341 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 29/197 (14%), Positives = 70/197 (35%), Gaps = 30/197 (15%) Query: 126 LELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVA 185 + +A+ + G+ + S + + L+A++ + + + A++ Sbjct: 41 VNALEAYGADLLGKEAALFVPSGTMSNLLAVM------------SHCQRGEGAVLG---- 84 Query: 186 YSSDQAH---SSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVAT 242 AH + + ++G V L+ +P + ++ + ++ A+ D + Sbjct: 85 ---SAAHIYRYEAQGSAVLGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVC-- 139 Query: 243 LGTTTCCSFDNL---LEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNF 299 L T L E+ + ++ + LH+D A +A + V DS + Sbjct: 140 LENTHNGKVLPLPYLREMRELVDEHGLQLHLDGARLFNAVVASGHTVR-ELVAPFDSVSI 198 Query: 300 NPHKWLLVNFDCSAMWV 316 K L ++ V Sbjct: 199 CLSKGLGAPV--GSLLV 213 >4ISY-A nrPDB Length = 404 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 23/179 (12%), Positives = 59/179 (32%), Gaps = 27/179 (15%) Query: 143 VIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIG 202 + +E+ +A+ + + +++ H +V + Sbjct: 74 IFTAGGTESDNLAVKGI-YWARRDAEPH-----------RRRIVTTEVEHHAVLDSVNWL 121 Query: 203 ----GVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVG 258 G + +P+ + ++ A+AL+EAL+ L+ + + E+ Sbjct: 122 VEHEGAHVTWLPTAADGSVSATALREALQSHDDVALVSVMWANN----EVGTILPIAEMS 177 Query: 259 PICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVK 317 + + + +H DA A +F G + + HK+ A+ ++ Sbjct: 178 VVAMEFGVPMHSDAIQAVGQLPL-DF-----GASGLSAMSVAGHKFGGPP-GVGALLLR 229 >2Z67-A nrPDB Length = 456 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Query: 191 AHSSVERAGLIGGVKLKAIPS--DGNFAMRA-SALQEALERDKAAGLIPFFMVATLGTTT 247 +H S +A G+ ++ + + DG+ ++ A++++ G P +++TL Sbjct: 185 SHKSPIKAVSFVGMNMRLVETVLDGDRVYVPVEDIENAIKKEIELGNRP-CVLSTLTFFP 243 Query: 248 CCSFDNLLEVGPICNKEDIWLHVDAAYA 275 + D+++E+ IC DI ++ AYA Sbjct: 244 PRNSDDIVEIAKICENYDIPHIINGAYA 271 >1M6S-A nrPDB Length = 347 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 42/243 (17%), Positives = 78/243 (32%), Gaps = 33/243 (13%) Query: 126 LELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVA 185 + + E G+ + S + V+++A + I+E Sbjct: 40 INELERLAAETFGKEAALFVPSGTMGNQVSIMA------------HTQRGDEVILE---- 83 Query: 186 YSSDQAH---SSVERAGLIGGVKLKAIPSDGNFAMRASALQEALE-RDKAAGLIPFFMVA 241 +H V ++ GV +P N AM +++A+ R+ + Sbjct: 84 ---ADSHIFWYEVGAMAVLSGVMPHPVPGK-NGAMDPDDVRKAIRPRNIHFPRTSLIAIE 139 Query: 242 TLGTTTCCSFDNLLEVGPIC---NKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFN 298 + L + IC + I +H+D A +A I + +ADS Sbjct: 140 NTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGV-PVKEYAGYADSVM 198 Query: 299 FNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFR 358 F K L ++ V R + A R L + +G++ I L + Sbjct: 199 FCLSKGLCAPV--GSVVVGDRDFIERA-RKARKMLGGGMRQAGVLAAAG--IIALTKMVD 253 Query: 359 SLK 361 LK Sbjct: 254 RLK 256 >4EB7-A nrPDB Length = 382 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 26/187 (13%), Positives = 55/187 (29%), Gaps = 26/187 (13%) Query: 137 AGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVE 196 G G V A+EA +A++ + + + + + + Q Sbjct: 58 GGGGTVVFTSGATEANNLAIIGYAMRNARKGKHILVSAVEHMSVINPAKFLQKQ------ 111 Query: 197 RAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLE 256 G +++ IP + S + + L D + + + E Sbjct: 112 ------GFEVEYIPVGKYGEVDVSFIDQKLRDDT------ILVSVQHANNEIGTIQPVEE 159 Query: 257 VGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWV 316 + + LH+DA S + AD + + + A+W+ Sbjct: 160 ISEVLAG-KAALHIDAT--ASVGQIEVDVEKIG----ADMLTISSND-IYGPKGVGALWI 211 Query: 317 KKRTDLT 323 +K L Sbjct: 212 RKEAKLQ 218 >3NNK-A nrPDB Length = 411 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 7/88 (7%) Query: 204 VKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNK 263 V +P F +++A++R + P ++ G T+ L E+G IC + Sbjct: 114 VHTIEVPWGEVFT--PDQVEDAVKRIR-----PRLLLTVQGDTSTTMLQPLAELGEICRR 166 Query: 264 EDIWLHVDAAYAGSAFICPEFRHLLNGV 291 D + DA + L+ V Sbjct: 167 YDALFYTDATASLGGNPLETDVWGLDAV 194 >3KGX-A nrPDB Length = 393 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 57/333 (17%), Positives = 104/333 (31%), Gaps = 60/333 (18%) Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNF--AMRASALQEAL------------ 226 L S H ++E A + + N MRA+ + + + Sbjct: 73 NPLTLVVSGSGHCAMETALFNLLEPGDSFLTGTNGIWGMRAAEIADRIGARVHQMIKKPG 132 Query: 227 ----ERDKAAGLI---PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDA-AYAGSA 278 ++ GL P + G ++ L G +C++ L VD+ A G Sbjct: 133 EHYTLQEVEEGLAQHKPVLLFLVHGESSTGVVQPLDGFGELCHRYQCLLLVDSVASLGGV 192 Query: 279 FICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLT--------GAFRLDP 330 I + + G++ S + K L S + + +F D Sbjct: 193 PIYMDQQ----GIDIMYSSS---QKVLNAPPGISLISFNDKAKYKVYSRKTKPVSFYTDI 245 Query: 331 TYLKHSHQDSGLITDYRHWQIPLGRRFRSL-KMWFVFRMYGVKGLQAYIRKHVQLSHEFE 389 TYL + G + R I SL + + +GL+ R+H + + Sbjct: 246 TYL---AKLWGCEGETR--VIHHTTPVTSLYCLRESLALIAEQGLENCWRRHREATAHLH 300 Query: 390 SLVR--------QDPRFEICVEVILGLVCFRLKGSN--KVNEALLQRINSAKKIHLVPCH 439 ++ +DP + + V G N + +L + L P Sbjct: 301 KHLQEMGLKFFVKDPEIRL---PTITTVTV-PAGYNWRDIVSYVLDHFSIEISGGLGPTE 356 Query: 440 LRDKFVLRFAICSRTVESAHVQRAWEHIKELAA 472 R VLR + + +V R E ++E Sbjct: 357 ER---VLRIGLLGYNATTENVDRVAEALREALQ 386 >6ONN-A nrPDB Length = 402 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 34/200 (17%), Positives = 56/200 (28%), Gaps = 28/200 (14%) Query: 81 PTASSYPAMLAD-MLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGE 139 ++ Y + A +L AI + A + L ++ + F Sbjct: 52 FASNDYLGLAAHPLLVAAITEGARRYGAGSGGSHLLGGHSRAHAQLEDDLAEFAGGFVDN 111 Query: 140 GGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAG 199 + + A L L A + + SD S+ A Sbjct: 112 PRALYFSTGYMANLATLTA--------------------LAGRGTTLFSD----SLNHAS 147 Query: 200 LIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGP 259 LI G +L A AL LE AA + + T+ + L + Sbjct: 148 LIDGARLSRADIQIYPHADAEALGAMLEASDAA--VKLIVSDTVFSMD-GDIAPLARLLE 204 Query: 260 ICNKEDIWLHVDAAYAGSAF 279 + WL VD A+ Sbjct: 205 LAEHHGAWLVVDDAHGFGVL 224 >4LNJ-A nrPDB Length = 333 Score = 37.7 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 40/210 (19%), Positives = 73/210 (34%), Gaps = 34/210 (16%) Query: 126 LELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVA 185 + + + E +G+ + + ++A LVALL + E + I+ + Sbjct: 36 VNALQDYAAELSGKEAAIFLPTGTQANLVALL------------SHCERGEEYIVGQ--- 80 Query: 186 YSSDQAH-SSVERAGL--IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVA- 241 AH E G +G ++ + I + + + + ++ D I F Sbjct: 81 ----AAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDD----IHFARTKL 132 Query: 242 -TLGTTTCCSFDN---LLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSF 297 +L T L E K ++ LHVD A +A + L ++ DSF Sbjct: 133 LSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCE-LKEITQYCDSF 191 Query: 298 NFNPHKWLLVNFDCSAMWVKKRTDLTGAFR 327 K L ++ V R + A R Sbjct: 192 TICLSKGLGTPV--GSLLVGNRDYIKRAIR 219 >2DR1-A nrPDB Length = 386 Score = 37.7 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 216 AMRASALQEALER--DKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDA- 272 A++ L +AL + D A + T T+ + L E+ + + D + VDA Sbjct: 131 AVKPEDLDDALRKNPDVEA------VTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAV 184 Query: 273 -AYAGS 277 A G+ Sbjct: 185 SAMGGA 190 >3ISL-A nrPDB Length = 416 Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 25/87 (28%), Gaps = 5/87 (5%) Query: 203 GVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICN 262 G + + + + +++ K P + G T+ L +G C Sbjct: 109 GANVHMLECEWGTVFDPEDIIREIKKVK-----PKIVAMVHGETSTGRIHPLKAIGEACR 163 Query: 263 KEDIWLHVDAAYAGSAFICPEFRHLLN 289 ED VDA ++ Sbjct: 164 TEDALFIVDAVATIGGCEVKVDEWKID 190 >2EPJ-A nrPDB Length = 434 Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 33/138 (23%), Positives = 49/138 (35%), Gaps = 11/138 (7%) Query: 115 ETVMMDWLGKMLELPKAFLNEK----AGEGGGV-IQGSASEATLVALLAARTKVIHRLQA 169 E + WL + L EK GG + S +EAT+ A+ AR L Sbjct: 83 EALARGWLYGAPGEAEVLLAEKILGYVKRGGMIRFVNSGTEATMTAIRLARGYTGRDLIL 142 Query: 170 ASPELTQAAIMEKLVAYSSDQAHSSVERAGLI-GGVKLKAIPSDGNFAMRASALQEALER 228 + LVA S AH V + + V + + N AL+ Sbjct: 143 KFDGCYHGSHDAVLVAAGSAAAHYGVPTSAGVPEAVARLTLVTPYN---DVEALERVFAE 199 Query: 229 --DKAAGLIPFFMVATLG 244 D+ AG+I ++A G Sbjct: 200 YGDRIAGVIVEPVIANAG 217 >5JAY-A nrPDB Length = 402 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 29/201 (14%), Positives = 55/201 (27%), Gaps = 30/201 (14%) Query: 81 PTASSYPAMLAD-MLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGE 139 ++ Y + A L AI + A + L ++ + F+ Sbjct: 52 FASNDYLGLAAHPQLIAAIAEGAQRYGAGSGGSHLLGGHSRAHAQLEDDLAEFVGGFVEN 111 Query: 140 GGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQ-AHSSVERA 198 + + A L L A + + SD H+S+ Sbjct: 112 ARALYFSTGYMANLATLTA--------------------LAGRGTTLFSDALNHASLIDG 151 Query: 199 GLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVG 258 + ++ P AL LE A + + T+ + L + Sbjct: 152 ARLSRADVQIYP-----HCDTDALSAMLEASDAD--VKVIVSDTVFSMD-GDIAPLPRLL 203 Query: 259 PICNKEDIWLHVDAAYAGSAF 279 + + WL VD A+ Sbjct: 204 ELAEQHGAWLIVDDAHGFGVL 224 >3WKR-A nrPDB Length = 416 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 48/135 (35%), Gaps = 11/135 (8%) Query: 189 DQAHSSVERAGLIGGVKLKAIPSDGNF---AMRASALQEALERDKAAGLIPFFMVATLGT 245 AH + A + + + + + + +E ++ + G ++ T Sbjct: 143 KNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYKEVIDNLEDKGKNVGLILLTHVD 202 Query: 246 TTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVE-FADSFNFNPHKW 304 + ++ +VG I ++ I ++ AY R +NG E AD + HK Sbjct: 203 GEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVG-------RMPVNGKEVKADFIVASGHKS 255 Query: 305 LLVNFDCSAMWVKKR 319 + + C + + Sbjct: 256 MAASAPCGILAFSEE 270 >5LUC-A nrPDB Length = 403 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 45/315 (14%), Positives = 89/315 (28%), Gaps = 62/315 (19%) Query: 120 DWLGKMLELPKAFLNEKAGE-------GGGVIQGSASEATLVALLAARTKVIHRLQAASP 172 L K L +P L G +Q S + + +++ ++ Sbjct: 23 KALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDM------YQIMDEIKEGIQ 76 Query: 173 ELTQAAIMEKLVAYSSDQAHSSVERA-------------GLIGGVKLKAIPSDGNFAMRA 219 + Q L S H ++E A G G +A+ R Sbjct: 77 YVFQT--RNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARV 134 Query: 220 SALQEA-----LERDKAAGLI---PFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVD 271 + + ++ GL P + T G ++ L G +C++ L V+ Sbjct: 135 HPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVN 194 Query: 272 --AAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLD 329 A+ G+ G++ S + K L S + + R Sbjct: 195 SVASLGGTPLYMDR-----QGIDILYSGS---QKALNAPPGTSLISFSDKAKKKMYSRKT 246 Query: 330 PTYLKHSH----------QDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIR 379 + + D + + I L SL + +GL+ R Sbjct: 247 KPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLAL------IAEQGLENSWR 300 Query: 380 KHVQLSHEFESLVRQ 394 +H + + ++ Sbjct: 301 QHREAAAYLHGRLQA 315 >2CH1-A nrPDB Length = 396 Score = 36.6 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 5/89 (5%) Query: 203 GVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICN 262 G ++ I + L A+E + P + T G ++ L VG IC+ Sbjct: 116 GADVRTIEGPPDRPFSLETLARAIELHQ-----PKCLFLTHGDSSSGLLQPLEGVGQICH 170 Query: 263 KEDIWLHVDAAYAGSAFICPEFRHLLNGV 291 + D L VDA + + ++ V Sbjct: 171 QHDCLLIVDAVASLCGVPFYMDKWEIDAV 199 >5VYE-A nrPDB Length = 346 Score = 36.2 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 42/298 (14%), Positives = 77/298 (25%), Gaps = 42/298 (14%) Query: 185 AYSSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVA 241 S+ AH + G + N + +++E + + +V Sbjct: 82 VICSETAHVETDECGAPEFFSNGSKLLTAASVNGKLTPQSIREVALKRQDIHYPKPRVVT 141 Query: 242 TLGTTTCCSF---DNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFN 298 T + D L + C + + LH+D A +A Sbjct: 142 ITQATEVGTVYRPDELKAISATCKELGLNLHMDGARFTNACAFLGCSPA--------ELT 193 Query: 299 FNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQI-PLGRRF 357 + V+ C + + + +D DYR Q L + Sbjct: 194 WKA----GVDVLC----FGGTKNGMAVGEAILFFNRQLAEDF----DYRCKQAGQLASKM 241 Query: 358 RSLKM-WFVFRMYGV-KGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKG 415 R L W G + QL LV P E+ V V Sbjct: 242 RFLSAPWVGLLEDGAWLRHGNHANHCAQL---LALLVSDLPGVELMFPVEANGVFL---- 294 Query: 416 SNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAAD 473 ++ E ++ + + + CS E V+ I+ + Sbjct: 295 --QMPEHAIEALRAKGWRFYTFIGSGGARFM----CSWDTEEERVRELAADIRSIITA 346 >1O69-A nrPDB Length = 394 Score = 36.2 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Query: 208 AIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIW 267 I D + + L+ A++ + P ++ T + + E+ IC + DI Sbjct: 98 FIDCDETYNIDVDLLKLAIKECEKK---PKALIL---THLYGNAAKMDEIVEICKENDIV 151 Query: 268 LHVDAAYAGSAF 279 L DAA A +F Sbjct: 152 LIEDAAEALGSF 163 >3UWC-A nrPDB Length = 374 Score = 35.4 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 26/71 (36%), Gaps = 9/71 (12%) Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 G + S+ + + ++ A+ DK ++P + ++ + I Sbjct: 98 AGATPVLVDSENGYVIDPEKIEAAI-TDKTKAIMPVHY--------TGNIADMPALAKIA 148 Query: 262 NKEDIWLHVDA 272 K ++ + DA Sbjct: 149 KKHNLHIVEDA 159 >2Z9W-A nrPDB Length = 392 Score = 35.1 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 35/219 (15%), Positives = 71/219 (32%), Gaps = 40/219 (18%) Query: 105 WAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVI 164 + PA L ++D K + L + G+ EA +L++ V+ Sbjct: 34 YDYDPAFQLLYEKVVDKAQKAMRLSNKPVILHGEPVLGL------EAAAASLISPDDVVL 87 Query: 165 HRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQE 224 + + + K Y + + S L I N A+ A+ + Sbjct: 88 N---------LASGVYGKGFGYWAKR--YSPH---------LLEIEVPYNEAIDPQAVAD 127 Query: 225 ALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDA--AYAGSAFICP 282 L+ ++ T + + + +G + + +L VDA ++ G Sbjct: 128 MLKAHPEITVVSVCHH----DTPSGTINPIDAIGALVSAHGAYLIVDAVSSFGGMKTHPE 183 Query: 283 EFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD 321 + + AD + P+K L + M V +R Sbjct: 184 DCK--------ADIYVTGPNKCLGAPPGLTMMGVSERAW 214 >5K8B-A nrPDB Length = 403 Score = 35.1 bits (79), Expect = 0.070, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 47/151 (31%), Gaps = 31/151 (20%) Query: 130 KAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSD 189 + L EK + S + A A++AA I+ +S Sbjct: 43 EQLLCEKMNVKHAHLLSSGTAALQTAMMAA-----------GIGAGDEVIVPPFTFVASV 91 Query: 190 QAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALE-RDKAAGLIPFFMVATLGTTTC 248 +A + G D + ++ + R KA L+ C Sbjct: 92 EAIF-------MAGAVPIFAEIDETLCLSPEGIEAVITPRTKAINLVHM----------C 134 Query: 249 CSFDNLLEVGPICNKEDIWLHVDA--AYAGS 277 S + E+ IC K ++ L DA A GS Sbjct: 135 GSMAKMDEIKAICKKHNLVLLEDACQAIGGS 165 >3HL2-A nrPDB Length = 501 Score = 34.7 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 33/208 (15%), Positives = 68/208 (32%), Gaps = 34/208 (16%) Query: 196 ERAGLIGGVKLKAIPSDGNFAMRASALQ---EALERDKAAGLIPFFMVATLGTTTCCSF- 251 +++ + P + L+ +A+E L P ++ TT+C + Sbjct: 172 QKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQE-LGPDCILCIHSTTSCFAPR 230 Query: 252 --DNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLL---NGVEFADSFNFNPHKWLL 306 D L E+ IC DI V+ AY + HL+ V D+F + K + Sbjct: 231 VPDRLEELAVICANYDIPHIVNNAYG---VQSSKCMHLIQQGARVGRIDAFVQSLDKNFM 287 Query: 307 VNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVF 366 V + + + Q+ + R P SL + Sbjct: 288 VPVGGAII---------------AGFNDSFIQEISKMYPGRASASP------SLDVLITL 326 Query: 367 RMYGVKGLQAYIRKHVQLSHEFESLVRQ 394 G G + +++ ++ + +++ Sbjct: 327 LSLGSNGYKKLLKERKEMFSYLSNQIKK 354 >1V72-A nrPDB Length = 356 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 22/146 (15%), Positives = 43/146 (29%), Gaps = 22/146 (15%) Query: 216 AMRASALQEALERDKAAGLI--PFFMVATLGTTTCCSF---DNLLEVGPICNKEDIWLHV 270 + L+E P + T T S D + +G +C + LH+ Sbjct: 120 KLDIVRLRERTREKVGDVHTTQPACVSITQAT-EVGSIYTLDEIEAIGDVCKSSSLGLHM 178 Query: 271 DAAYAGSAFICPEFRH----LLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTG-A 325 D + +A + GV D+ +F K + + + L + Sbjct: 179 DGSRFANALVSLGCSPAEMTWKAGV---DALSFGATK--------NGVLAAEAIVLFNTS 227 Query: 326 FRLDPTYLKHSHQDSGLITDYRHWQI 351 + +Y + + QI Sbjct: 228 LATEMSYRRKRAGHLSSKMRFLSAQI 253 >3WY7-A nrPDB Length = 404 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 32/183 (17%), Positives = 59/183 (32%), Gaps = 21/183 (11%) Query: 109 PACTELETVMMDWLG------KMLELPKAFLNEKAGEGGGVIQGSASEAT------LVAL 156 P EL+ D+LG + +A G GG + +E L + Sbjct: 55 PVAAELDLASNDYLGLSQHPDVLDGGVEALRTWGGGAGGSRLVTGNTELHEAFEHQLASF 114 Query: 157 LAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQ-AHSSVERAGLIGGVKLKAIPSDGNF 215 L A + ++ + A+ SD +H+S+ A + ++ P Sbjct: 115 LGAESALVFSSGYTANLGALVALSGPGSLIVSDALSHASLVDACRLSRARVVVSPHRDVD 174 Query: 216 AMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYA 275 A+ A+ ER +V + L ++ +C + L VD A+ Sbjct: 175 AVDAALAARTEERAV--------VVTESVFSADGDLAPLRDLHAVCRRHGALLLVDEAHG 226 Query: 276 GSA 278 Sbjct: 227 LGV 229 >2C81-A nrPDB Length = 418 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 28/67 (41%), Gaps = 10/67 (14%) Query: 208 AIPSDGN-FAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDI 266 + + + + + ++ A+ DK +IP + S N+ E+ I + ++ Sbjct: 108 FVDVEADTYCIDPQLIKSAI-TDKTKAIIPVHL--------FGSMANMDEINEIAQEHNL 158 Query: 267 WLHVDAA 273 ++ D A Sbjct: 159 FVIEDCA 165 >4PIW-A nrPDB Length = 396 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 36/228 (15%), Positives = 71/228 (31%), Gaps = 40/228 (17%) Query: 194 SVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDN 253 S A ++ G K+ + + L EA DK ++P C D Sbjct: 103 STANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTRVIVPVHYAGVA-----CEMDT 157 Query: 254 LLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNG-VEFADSFNFNPHKWLLVNFDCS 312 ++ + K ++++ DAA + ++ G + F+F+ K + Sbjct: 158 IMAL---AKKHNLFVVEDAAQG----VMSTYKGRALGTIGHIGCFSFHETKNYTAGGEGG 210 Query: 313 AMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIP---LGRRFRSLKMW------ 363 A + + + A + S G + Y I L ++ +W Sbjct: 211 ATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAA 270 Query: 364 --------FVFRMY----------GVKGLQAYIRKHVQLSHEFESLVR 393 +++ Y G L + VQ +H F +R Sbjct: 271 DRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCVQNAHMFYIKLR 318 >2DOU-A nrPDB Length = 376 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 32/86 (37%), Gaps = 8/86 (9%) Query: 198 AGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEV 257 A + ++ IP + A+ E + R+ L+ + T F+ + Sbjct: 127 AARVASLRTFLIPLREDGLADLKAVPEGVWREAKVLLLNYPNNPTGAVADWGYFE--EAL 184 Query: 258 GPICNKEDIWL-----HVDAAYAGSA 278 G + K +WL +VD Y G A Sbjct: 185 G-LARKHGLWLIHDNPYVDQVYEGEA 209 >2HUU-A nrPDB Length = 393 Score = 33.1 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 37/89 (41%), Gaps = 9/89 (10%) Query: 203 GVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICN 262 G ++ + S ++ +++AL K P + T G ++ L VG +C+ Sbjct: 117 GADVRVVKSKVGQSLSLDEIRDALLIHK-----PSVLFLTQGDSSTGVLQGLEGVGALCH 171 Query: 263 KEDIWLHVD--AAYAGSAFICPEFRHLLN 289 + + L VD A+ G+ R ++ Sbjct: 172 QHNCLLIVDTVASLGGAPMFM--DRWEID 198 >1VJO-A nrPDB Length = 393 Score = 33.1 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 44/254 (17%), Positives = 70/254 (27%), Gaps = 61/254 (24%) Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 V+ + P F++ L+ ALE + P + T+ + L VG +C Sbjct: 133 ADVRTISKPWGEVFSL--EELRTALETHR-----PAILALVHAETSTGARQPLEGVGELC 185 Query: 262 NKEDIWLHVD--AAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAM----- 314 + L VD + G + GV+ A S + K L + S Sbjct: 186 REFGTLLLVDTVTSLGGVPIFLDAW-----GVDLAYSCS---QKGLGCSPGASPFTMSSR 237 Query: 315 --------------WVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360 W L + + Y H L R Sbjct: 238 AIEKLQRRRTKVANWYLDMNLLGKYWGSERVY--HHTAPINLYYALREA----------- 284 Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVE-----VILGLVCFRL-K 414 R+ +GL ++H + + +D + VE L VC Sbjct: 285 -----LRLIAQEGLANCWQRHQKNVEYLWERL-EDIGLSLHVEKEYRLPTLTTVCIPDGV 338 Query: 415 GSNKVNEALLQRIN 428 V LL N Sbjct: 339 DGKAVARRLLNEHN 352 >6MQH-A nrPDB Length = 308 Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 22/63 (34%) Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 G V P + + +A ++ ++ G +V T G + S D + + Sbjct: 21 GSVPAIVTPMLEDGGLDLAAFRKLIDWHIEEGTDALVVVGTSGESATLSVDEHVLMIETA 80 Query: 262 NKE 264 K Sbjct: 81 VKH 83 >5A9K-A nrPDB Length = 305 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 9/78 (11%) Query: 276 GSAFICPEFRHLLNGVEFADSFNFNPHK---WLLVNFDCSAMWVKKRTDLTGAFRLDPTY 332 G + +C H L G +F HK WL D A V T +R TY Sbjct: 138 GKSMLCNSLIHFLGG----SVLSFANHKSHFWLASLADTRAALVDDATH--ACWRYFDTY 191 Query: 333 LKHSHQDSGLITDYRHWQ 350 L+++ + D +H Sbjct: 192 LRNALDGYPVSIDRKHKA 209 >2GXA-A nrPDB Length = 274 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 9/78 (11%) Query: 276 GSAFICPEFRHLLNGVEFADSFNFNPHK---WLLVNFDCSAMWVKKRTDLTGAFRLDPTY 332 G + +C H L G +F HK WL D A V T +R TY Sbjct: 135 GKSMLCNSLIHFLGG----SVLSFANHKSHFWLASLADTRAALVDDATH--ACWRYFDTY 188 Query: 333 LKHSHQDSGLITDYRHWQ 350 L+++ + D +H Sbjct: 189 LRNALDGYPVSIDRKHKA 206 >3LWS-A nrPDB Length = 357 Score = 32.7 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 56/162 (34%), Gaps = 39/162 (24%) Query: 122 LGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASP--------- 172 G ++E + + G V S + A VAL + +R A P Sbjct: 45 TGAIIEPFEQKFADVLGMDDAVFFPSGTMAQQVALRIWSDETDNRTVAYHPLCHLEIHEQ 104 Query: 173 -ELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKA 231 L + +E ++ ++D L+ ++KA+P + L L + + Sbjct: 105 DGLKELHPIETILVGAAD---------RLMTLDEIKALP-------DIACLLLELPQREI 148 Query: 232 AGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAA 273 G+ P +F L + C + I LH+D A Sbjct: 149 GGVAP-------------AFSELETISRYCRERGIRLHLDGA 177 >3PJ0-A nrPDB Length = 359 Score = 32.7 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 51/138 (36%), Gaps = 22/138 (15%) Query: 138 GEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVER 197 G+ V S + A +AL + +R A P + L + D + Sbjct: 62 GKQSAVFFPSGTMAQQIALRIWADRKENRRVAYHP-------LSHLEIHEQDGLKELQQI 114 Query: 198 AGLIGGVKLKAIPSDGNFAMRASALQEALE--RDKAAGLIPFFMVATLGTTTCCSFDNLL 255 L+ G + + D ++R +E + + G +P +F+ L Sbjct: 115 TPLLLGTANQLLTIDDIKSLREPVSSVLIELPQREIGGQLP-------------AFEELE 161 Query: 256 EVGPICNKEDIWLHVDAA 273 ++ C+++ I LH+D A Sbjct: 162 KISEYCHEQGISLHLDGA 179 >1IAY-A nrPDB Length = 428 Score = 32.7 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 11/89 (12%) Query: 205 KLKAIP----SDGNFAMRASALQEALERD-----KAAGLIPFFMVATLGTTTCCSFDNLL 255 ++ IP S NF + + A++EA E K GLI LGTT D L Sbjct: 154 GVQLIPIHCESSNNFKITSKAVKEAYENAQKSNIKVKGLILTNPSNPLGTTLDK--DTLK 211 Query: 256 EVGPICNKEDIWLHVDAAYAGSAFICPEF 284 V N+ +I L D YA + F P+F Sbjct: 212 SVLSFTNQHNIHLVCDEIYAATVFDTPQF 240 >2OGE-A nrPDB Length = 399 Score = 32.4 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 22/161 (13%), Positives = 52/161 (32%), Gaps = 17/161 (10%) Query: 191 AHSSVERAGLIGGVKLKAIPSD---GNFAMRASALQEALERDKAAGLIPFFMVATLGTTT 247 +H+ + + +P + + + +++A+ + L+P + Sbjct: 110 SHTYIASWLAVSATGATPVPVEPHEDHPTLDPLLVEKAI-TPRTRALLPVHL-------- 160 Query: 248 CCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVE-FADSFNFNPHKWLL 306 ++ + + ++ + + DAA A A +R G +F+F P K L Sbjct: 161 YGHPADMDALRELADRHGLHIVEDAAQAHGA----RYRGRRIGAGSSVAAFSFYPGKNLG 216 Query: 307 VNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYR 347 D A+ L + + T+ R Sbjct: 217 CFGDGGAVVTGDPELAERLRMLRNYGSRQKYSHETKGTNSR 257 >3BC8-A nrPDB Length = 450 Score = 32.4 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 68/208 (32%), Gaps = 34/208 (16%) Query: 196 ERAGLIGGVKLKAIPSDGNFAMRASALQ---EALERDKAAGLIPFFMVATLGTTTCCSF- 251 +++ V P + L+ +A+E L P ++ TT C + Sbjct: 154 QKSCFKSMVTAGFEPVVIENVLEGDELRTDLKAVEAKIQE-LGPEHILCLHSTTACFAPR 212 Query: 252 --DNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLL---NGVEFADSFNFNPHKWLL 306 D L E+ IC DI V+ AY + HL+ V D+F + K + Sbjct: 213 VPDRLEELAVICANYDIPHVVNNAYG---LQSSKCMHLIQQGARVGRIDAFVQSLDKNFM 269 Query: 307 VNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVF 366 V + + + + QD + R P SL + Sbjct: 270 VPVGGAII---------------AGFNEPFIQDISKMYPGRASASP------SLDVLITL 308 Query: 367 RMYGVKGLQAYIRKHVQLSHEFESLVRQ 394 G G + +++ ++ + +++ Sbjct: 309 LSLGCSGYRKLLKERKEMFVYLSTQLKK 336 >6MRE-A nrPDB Length = 420 Score = 32.4 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 56/178 (31%), Gaps = 26/178 (14%) Query: 143 VIQGSASEA-TLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLI 201 V +E LVA + V ++ A + + Sbjct: 103 VFVAGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCAR------------ 150 Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261 G +L+ IP + + ++ L + + T + + + L E+ + Sbjct: 151 VGAELRVIPLNPDGTLQLETLPTLFDEKTR------LLAITHVSNVLGTENPLAEMITLA 204 Query: 262 NKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKR 319 ++ + VD A A P L+ D + F+ HK L ++VK+ Sbjct: 205 HQHGAKVLVDGAQA--VMHHPVDVQALD----CDFYVFSGHK-LYGPTGIGILYVKEA 255 >6HRH-B nrPDB Length = 469 Score = 32.0 bits (71), Expect = 0.68, Method: Composition-based stats. Identities = 51/293 (17%), Positives = 91/293 (31%), Gaps = 43/293 (14%) Query: 167 LQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEAL 226 + S T A I+ YS H+S+ + G + L++ L Sbjct: 142 VANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHN-----DPDHLKKLL 196 Query: 227 ERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRH 286 E+ IP + + + L E+ + ++ VD +A + Sbjct: 197 EKSNPK--IPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGL-----YGS 249 Query: 287 LLNGVEFADSFNFNPHKW------LLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDS 340 G+ D HK L F C ++ DL R + Sbjct: 250 RGAGIGERDGIM---HKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYA---------A 297 Query: 341 GLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEI 400 G I + L S+++ + G +G QA R H + L+ Sbjct: 298 GFIFTTSLPPMVLSGALESVRL-----LKGEEG-QALRRAHQRNVKHMRQLLMDRGL--P 349 Query: 401 CVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHL----VPCHLRDKFVLRFA 449 + ++ R G+ +N L + S I++ P R + +LR A Sbjct: 350 VIPCPSHIIPIR-VGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLA 401 >2YRI-A nrPDB Length = 353 Score = 31.2 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 26/78 (33%), Gaps = 8/78 (10%) Query: 217 MRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG 276 + A+ AL+R + + G T+ + +G + + +DA Sbjct: 111 VDPEAVARALKRRRYR-----MVALVHGETSTGVLNPAEAIGALAKEAGALFFLDAVTTL 165 Query: 277 SAFICPEFRHLLNGVEFA 294 F GV++A Sbjct: 166 GMLP---FSMRAMGVDYA 180 >5W1B-A nrPDB Length = 467 Score = 31.2 bits (69), Expect = 0.99, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 10/96 (10%) Query: 186 YSSDQAHSSVERAGLIGGVKLKAIPSDG----NFAMRASALQEALERDKAAGLIPFFMVA 241 + + AH + I V KA S+ L+E + + A ++ +V+ Sbjct: 132 FDTTAAHVELNGCKAINIVTEKAFDSETYDDWKGDFDIKKLKENIAQHGADNIV--AIVS 189 Query: 242 TLGTTTCC----SFDNLLEVGPICNKEDIWLHVDAA 273 T+ + S NL EV I + I++ +D+A Sbjct: 190 TVTCNSAGGQPVSMSNLKEVYEIAKQHGIFVVMDSA 225 >6FYQ-A nrPDB Length = 484 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 42/134 (31%), Gaps = 6/134 (4%) Query: 144 IQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGG 203 SE+ A+ R + + ++ VA +S E G+ G Sbjct: 147 FTSGGSESNDSAVKLVRHYWKIQGKPNKRKIISLKRSYHGVAAASTSVTGIPEFWGMAGH 206 Query: 204 VKLKAIPSDGNFAMRAS----ALQEALERDKAAGLIPFFM--VATLGTTTCCSFDNLLEV 257 + + D ++ +L +A+E + FF V G D L + Sbjct: 207 MMTDFLHVDTHYNNTTEQAVQSLCQAIEEAGPETIAAFFAEPVQGAGGVIIPPEDYFLRI 266 Query: 258 GPICNKEDIWLHVD 271 +CN I D Sbjct: 267 REVCNAYGILFVAD 280 >2GMS-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 28/187 (14%), Positives = 65/187 (34%), Gaps = 39/187 (20%) Query: 75 YFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLN 134 + Y +S++ + + + F+ +G+ ++ + Sbjct: 2 HMINYPLASSTWDDLEYKAIQSVLDSKMFT-----------------MGEYVKQYETQFA 44 Query: 135 EKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSS 194 + G V+ S S A L+ + A RL+ I+ V++S+ + Sbjct: 45 KTFGSKYAVMVSSGSTANLLMIAALFFTKKPRLKKG------DEIIVPAVSWST--TYYP 96 Query: 195 VERAGLIGGVKLKAIPSDGN-FAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDN 253 +++ G+++K + D N + +L+EA+ A L + +N Sbjct: 97 LQQ----YGLRVKFVDIDINTLNIDIESLKEAVTDSTK---------AILTVNLLGNPNN 143 Query: 254 LLEVGPI 260 E+ I Sbjct: 144 FDEINKI 150 >2ZC0-A nrPDB Length = 407 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 5/77 (6%) Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGL-IPFFMVATLGTTTCC---SFDNLLEV 257 G K++ +P D + MR L+E ++ KA G + G S + + Sbjct: 142 LGAKIEGVPVDNDG-MRVDLLEEKIKELKAKGQKVKLIYTIPTGQNPMGVTMSMERRKAL 200 Query: 258 GPICNKEDIWLHVDAAY 274 I +K D+ + D AY Sbjct: 201 LEIASKYDLLIIEDTAY 217 >1WYT-A nrPDB Length = 438 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 24/65 (36%), Gaps = 2/65 (3%) Query: 364 FVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVE-VILGLVCFRLKGSNK-VNE 421 G +GL+ K V+++H+ +L+ + P L + V Sbjct: 332 MYLAALGPEGLREVALKSVEMAHKLHALLLEVPGVRPFTPKPFFNEFALALPKDPEAVRR 391 Query: 422 ALLQR 426 AL +R Sbjct: 392 ALAER 396 >4LHD-A nrPDB Length = 983 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 39/94 (41%), Gaps = 5/94 (5%) Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240 ++ + + AH + + ++ G+++ + DG + L E+ G ++ Sbjct: 612 QRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKY---GDRLAALM 668 Query: 241 ATLGTTTCCSFD-NLLEVGPICNKEDIWLHVDAA 273 T +T F+ + + I ++ +++D A Sbjct: 669 VTYPST-HGVFEATIGTICDIVHRFGGEVYMDGA 701 >1DJ9-A nrPDB Length = 384 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 58/170 (34%), Gaps = 50/170 (29%) Query: 114 LETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGS--ASEATLVALLAARTKVIHRLQAAS 171 LE + +WLG L + A++A + A++A ++ + + Sbjct: 89 LEEELAEWLGYSRAL--------------LFISGFAANQAVIAAMMAKEDRIAADRLSHA 134 Query: 172 PELTQAAIME-KLVAYS-SDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERD 229 L A++ +L ++ +D H + A G ++ + ++G F+M + Sbjct: 135 SLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQM--VVTEGVFSMDGDSA------- 185 Query: 230 KAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAF 279 L E+ + + + WL VD A+ Sbjct: 186 -----------------------PLAEIQQVTQQHNGWLMVDDAHGTGVI 212 >4WB0-B nrPDB Length = 414 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 45/140 (32%), Gaps = 15/140 (10%) Query: 174 LTQAAIMEKLVAYSSDQA---HSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDK 230 LT EK Y +D H S+ +A ++ A + +++ + Sbjct: 123 LTHVFDAEKTPIYLADPTWPNHYSIVKAAGWKDIRTYAYYDHKTLGLDFEGMKKDILAAP 182 Query: 231 AAGLIPFFMVATLGTTTCCSFDNLLEVGP--ICNKEDIWLHVDAAYAGSAFICPEFRHL- 287 + A T S + E+ + ++ D+AY G A + Sbjct: 183 DGSVFLLHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFF--DSAYQGYASGSLDTDAYA 240 Query: 288 -----LNGVE--FADSFNFN 300 G+E A SF+ N Sbjct: 241 ARLFARRGIEVLLAQSFSKN 260 >3CAI-A nrPDB Length = 406 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 42/256 (16%), Positives = 76/256 (29%), Gaps = 38/256 (14%) Query: 81 PTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEG 140 P P +A + A G S + ++D + + + + Sbjct: 33 PAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVA------DLVNADP 86 Query: 141 GGVIQGSASEATLVALLAARTKVIHRLQAAS--PELTQAAIMEKLVAYSSDQAHSSVERA 198 GGV+ A A L++LLA + L L A + + RA Sbjct: 87 GGVVL-GADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWL------------RA 133 Query: 199 GLIGGVKLKAIPSD-GNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEV 257 G K+K D + + + + + + GT +L + Sbjct: 134 AHRYGAKVKWAEVDIETGELPTWQWESLISKSTRL----VAVNSASGT--LGGVTDLRAM 187 Query: 258 GPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVK 317 + + + VD + A +R L AD N H W AM + Sbjct: 188 TKLVHDVGALVVVDHSAAAP------YRLLDIRETDADVVTVNAHAWGGPPI--GAMVFR 239 Query: 318 KRTDL--TGAFRLDPT 331 + + G+ +P Sbjct: 240 DPSVMNSFGSVSTNPY 255 >2EH6-A nrPDB Length = 375 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 23/146 (15%), Positives = 49/146 (33%), Gaps = 8/146 (5%) Query: 127 ELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELT-QAAIMEKLVA 185 EL + EG S +E+ A+ AR + + ++ + + + Sbjct: 74 ELAHKLVKHFWTEGKVFFANSGTESVEAAIKLARKYWRDKGKNKWKFISFENSFHGRTYG 133 Query: 186 YSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGT 245 S + + ++ + L+ + AG+I + G Sbjct: 134 SLSATGQPKFHKGFEPLVPGFSYAKLN-----DIDSVYKLLDE-ETAGIIIEVIQGEGGV 187 Query: 246 TTCCSFDNLLEVGPICNKEDIWLHVD 271 S D L ++ IC ++D+ L +D Sbjct: 188 NE-ASEDFLSKLQEICKEKDVLLIID 212 >5ZME-A nrPDB Length = 687 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 42/106 (39%), Gaps = 8/106 (7%) Query: 315 WVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGL 374 + +T PTYL ++ S L+ R QIP R V ++ G + Sbjct: 239 LFRDKTQTEFIIATIPTYL-GVNESSRLLQALRAEQIPCKRI-------IVNQIVGPQQG 290 Query: 375 QAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420 AY+R ++ +V DP +VI +V ++G ++ Sbjct: 291 DAYLRMKMKDQIAALEMVANDPGLRPLRKVIAPMVDVEVRGVPALS 336 >2RIL-A nrPDB Length = 99 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 24/59 (40%) Query: 176 QAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGL 234 M + Y S Q H S++ + + S+ +F A +++AL + GL Sbjct: 29 HRDFMAQQPGYLSTQLHQSIDEGATYQLINVAIWQSEADFYQAAQKMRQALGHVQVEGL 87 >6CA8-A nrPDB Length = 751 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 216 AMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDI 266 M + LQ+A E F + +TL TT FD L++ + DI Sbjct: 525 KMDPAKLQKAEEEGLEK---VFKLKSTLTTTNMTLFDPNLKLQRYSTELDI 572 >5G0A-A nrPDB Length = 483 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 40/133 (30%), Gaps = 26/133 (19%) Query: 36 GYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLAD--- 92 YL +P E D +IMP T FF + L Sbjct: 19 KYLMRTFSTQNEYQPVPIESTEGDY--LIMPDGTRLL--DFFNQLYCVN-----LGQKNQ 69 Query: 93 ----MLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELP-KAFLNEKAGEGGGVIQGS 147 + A+ GF W T D+ K ++ + L ++ G + Sbjct: 70 KVNAAIKEALDRYGFVWD---------TYATDYKAKAAKIIIEDILGDEDWPGKVRFVST 120 Query: 148 ASEATLVALLAAR 160 SEA AL AR Sbjct: 121 GSEAVETALNIAR 133 >2X8U-A nrPDB Length = 412 Score = 30.0 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 28/89 (31%), Gaps = 7/89 (7%) Query: 191 AHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCS 250 +H+S+ +G ++ + L + L R A + + Sbjct: 137 SHASIYDGCWLGDAEIVRFRHNS-----VEDLDKRLGRLPAEAGKLVVLEGVY--SMMGD 189 Query: 251 FDNLLEVGPICNKEDIWLHVDAAYAGSAF 279 L E+ + K + VD A+ F Sbjct: 190 IAPLQEMVAVSKKHGAMILVDEAHGMGFF 218 >2BWN-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 37/101 (36%), Gaps = 7/101 (6%) Query: 175 TQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGL 234 T + L+ YS H+S+ I G+K A P + L+E + D A Sbjct: 125 TLRVLFPGLIIYSDSLNHASM-----IEGIKRNAGPKRIFRHNDVAHLRELIAADDPAA- 178 Query: 235 IPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYA 275 P + + F + E+ I + ++D +A Sbjct: 179 -PKLIAFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHA 218 >6CJQ-A nrPDB Length = 456 Score = 28.9 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 3/54 (5%) Query: 3 ASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDI 56 + E +RR E DY+ G E R+V ++ P LR + A D E + Sbjct: 268 SPELQRRIIEYFDYLWETRRGYEEREVLKEL-PHPLR--LAVAMEIHGDVIEKV 318 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.133 0.343 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,057,507 Number of Sequences: 36641 Number of extensions: 647598 Number of successful extensions: 2543 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 69 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 2334 Number of HSP's gapped (non-prelim): 134 length of query: 480 length of database: 10,336,785 effective HSP length: 101 effective length of query: 379 effective length of database: 6,636,044 effective search space: 2515060676 effective search space used: 2515060676 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (20.8 bits) S2: 61 (28.1 bits)