BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20231 (275 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4MPW-A nrPDB 507 e-144 1LTO-A nrPDB 478 e-135 3DFJ-A nrPDB 195 2e-50 3E0N-B nrPDB 193 6e-50 2F83-A nrPDB 181 3e-46 6AOD-C nrPDB 178 2e-45 5TJX-A nrPDB 178 2e-45 5GVT-A nrPDB 175 2e-44 6I44-A nrPDB 171 4e-43 2CGA-A nrPDB 171 5e-43 2V35-A nrPDB 166 1e-41 5FXL-A nrPDB 161 2e-40 4AN7-A nrPDB 160 6e-40 5UGG-A nrPDB 159 2e-39 2TLD-E nrPDB 157 3e-39 3P8G-A nrPDB 156 8e-39 4DUR-A nrPDB 156 1e-38 1ELT-A nrPDB 155 1e-38 1A0J-A nrPDB 155 1e-38 1F7Z-A nrPDB 155 3e-38 2F91-A nrPDB 151 2e-37 4DGJ-A nrPDB 151 2e-37 3F6U-H nrPDB 150 6e-37 4WWY-A nrPDB 150 8e-37 1EKB-B nrPDB 149 1e-36 2OQ5-A nrPDB 149 1e-36 3W94-A nrPDB 149 2e-36 1PYT-D nrPDB 148 2e-36 1BRU-P nrPDB 147 6e-36 1UTJ-A nrPDB 145 2e-35 3T2N-A nrPDB 145 2e-35 1P57-B nrPDB 144 3e-35 1FIW-A nrPDB 144 3e-35 5C67-A nrPDB 144 3e-35 3LC3-A nrPDB 143 7e-35 1X7A-C nrPDB 143 1e-34 4H4F-A nrPDB 142 2e-34 2EEK-A nrPDB 138 2e-33 1BDA-A nrPDB 138 2e-33 4Z6A-H nrPDB 135 2e-32 4NFE-A nrPDB 135 2e-32 1MKW-K nrPDB 134 3e-32 1ETT-H nrPDB 134 5e-32 5LHN-A nrPDB 134 5e-32 1AZZ-A nrPDB 132 1e-31 2OCV-B nrPDB 132 1e-31 1FIZ-A nrPDB 132 2e-31 3NXP-A nrPDB 132 2e-31 5FCR-A nrPDB 131 3e-31 1SC8-U nrPDB 131 3e-31 4NZQ-A nrPDB 131 3e-31 3K65-B nrPDB 131 3e-31 4XDE-A nrPDB 131 4e-31 1FDP-A nrPDB 131 4e-31 1FON-A nrPDB 130 5e-31 1YM0-A nrPDB 129 1e-30 6BQM-A nrPDB 129 2e-30 1YC0-A nrPDB 129 2e-30 1EUF-A nrPDB 128 3e-30 2R0L-A nrPDB 128 3e-30 1VR1-H nrPDB 127 6e-30 2B9L-A nrPDB 127 8e-30 1MZD-A nrPDB 126 1e-29 1FXY-A nrPDB 125 2e-29 5ZFH-A nrPDB 125 3e-29 1FI8-A nrPDB 124 3e-29 1SI5-H nrPDB 124 3e-29 1A5I-A nrPDB 124 5e-29 1C5M-D nrPDB 124 5e-29 3QUM-P nrPDB 122 1e-28 5TO3-B nrPDB 122 2e-28 5MS3-A nrPDB 122 2e-28 5KWM-A nrPDB 122 2e-28 1PQ7-A nrPDB 121 2e-28 3BSQ-A nrPDB 121 3e-28 1SGF-G nrPDB 121 4e-28 2XRC-A nrPDB 120 5e-28 1KIG-H nrPDB 119 1e-27 1GPZ-A nrPDB 119 2e-27 5O32-I nrPDB 119 2e-27 2QY0-B nrPDB 118 3e-27 1MD7-A nrPDB 117 4e-27 3G01-A nrPDB 117 4e-27 4LK4-A nrPDB 117 5e-27 1EQ9-A nrPDB 116 9e-27 2PSX-A nrPDB 115 2e-26 3RP2-A nrPDB 115 3e-26 2ASU-B nrPDB 114 6e-26 6QHB-A nrPDB 113 1e-25 1SPJ-A nrPDB 111 3e-25 1NN6-A nrPDB 111 4e-25 1KYN-A nrPDB 110 5e-25 3TK9-A nrPDB 109 1e-24 4GSO-A nrPDB 109 1e-24 2BDH-A nrPDB 109 1e-24 1FUJ-A nrPDB 109 1e-24 4IW4-E nrPDB 109 1e-24 1TON-A nrPDB 108 2e-24 3I77-A nrPDB 108 3e-24 4BXW-A nrPDB 108 3e-24 4IGD-A nrPDB 108 3e-24 4DJZ-B nrPDB 107 5e-24 3BEU-A nrPDB 107 5e-24 1ORF-A nrPDB 106 8e-24 1M9U-A nrPDB 106 1e-23 4KKD-A nrPDB 106 1e-23 2RDL-A nrPDB 105 2e-23 1IAU-A nrPDB 105 2e-23 4E7N-A nrPDB 105 3e-23 1NPM-A nrPDB 105 3e-23 2AIQ-A nrPDB 105 3e-23 2ZKS-A nrPDB 104 3e-23 1AO5-A nrPDB 103 1e-22 2OLG-A nrPDB 102 1e-22 1OP0-A nrPDB 102 2e-22 4Q7Y-A nrPDB 102 3e-22 1SGF-A nrPDB 101 3e-22 3S9B-A nrPDB 100 5e-22 1Q3X-A nrPDB 100 9e-22 5XRF-A nrPDB 100 1e-21 4FXG-H nrPDB 100 1e-21 2FMJ-A nrPDB 99 1e-21 1ZJK-A nrPDB 99 1e-21 1BQY-A nrPDB 98 3e-21 3VGC-B nrPDB 97 6e-21 5UBM-A nrPDB 97 1e-20 1GVZ-A nrPDB 97 1e-20 5LPF-A nrPDB 96 2e-20 1ELV-A nrPDB 96 2e-20 1AE5-A nrPDB 95 3e-20 4J1Y-A nrPDB 94 5e-20 2JET-B nrPDB 94 6e-20 2XXL-A nrPDB 94 7e-20 2HLC-A nrPDB 92 3e-19 5XW8-A nrPDB 90 8e-19 4F4O-C nrPDB 90 1e-18 3S69-A nrPDB 88 3e-18 2PKA-B nrPDB 88 4e-18 3RU4-E nrPDB 85 4e-17 2JET-C nrPDB 84 5e-17 4X0L-C nrPDB 84 6e-17 4WJG-C nrPDB 83 1e-16 1AKS-B nrPDB 82 2e-16 1PPF-E nrPDB 81 4e-16 2I6S-A nrPDB 77 6e-15 1BBR-H nrPDB 75 3e-14 1BBR-E nrPDB 74 9e-14 2HNT-F nrPDB 74 9e-14 1RIW-B nrPDB 71 4e-13 1DLE-A nrPDB 66 2e-11 2WIN-I nrPDB 65 4e-11 2OK5-A nrPDB 65 5e-11 3H7T-A nrPDB 63 1e-10 3H7O-A nrPDB 60 1e-09 2KAI-A nrPDB 51 6e-07 1EPT-B nrPDB 50 1e-06 2HNT-E nrPDB 43 1e-04 2HNT-C nrPDB 43 2e-04 3F1S-B nrPDB 36 0.016 3H5C-B nrPDB 36 0.016 >4MPW-A nrPDB Length = 245 Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust. Identities = 244/245 (99%), Positives = 244/245 (99%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPV VSSHVHTVTLPPASETFP Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFP 120 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML Sbjct: 121 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 180 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY Sbjct: 181 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 240 Query: 271 VPKKP 275 VPKKP Sbjct: 241 VPKKP 245 >1LTO-A nrPDB Length = 245 Score = 478 bits (1229), Expect = e-135, Method: Compositional matrix adjust. Identities = 228/245 (93%), Positives = 234/245 (95%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQEAPRSKWPWQVSLRV YWMHFCGGSLIHPQWVLTAAHC+GPDVKDLA LRVQL Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 REQHLYYQDQLLPVSRIIVHPQFY Q GADIALLELEEPVN+SS VHTV LPPASETFP Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETFP 120 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PGMPCWVTGWGDVDNDE LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI+RDDML Sbjct: 121 PGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDML 180 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CAGN++RDSC+GDSGGPLVCKVNGTWLQAGVVSW EGCAQPNRPGIYTRVTYYLDWIHHY Sbjct: 181 CAGNSQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDWIHHY 240 Query: 271 VPKKP 275 VPKKP Sbjct: 241 VPKKP 245 >3DFJ-A nrPDB Length = 263 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 104/248 (41%), Positives = 144/248 (58%), Gaps = 10/248 (4%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GG A +WPWQVS+ G +H CGGSL+ QWVL+AAHC P A V+L Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCF-PSEHHKEAYEVKL 56 Query: 91 REQHL--YYQD-QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L Y +D ++ + II HP + DIALL+L P+ S ++ ++LP A+ Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANA 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 +FP G+ C VTGWG V L P PL+Q++VP++ C+A Y++ A ++ V++ Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKP-EEPHFVQE 175 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 DM+CAG +D+CQGDSGGPL C V G W G+VSWG+ C NRPG+YT + Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 235 Query: 266 WIHHYVPK 273 WI V + Sbjct: 236 WIQSKVTE 243 >3E0N-B nrPDB Length = 271 Score = 193 bits (491), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 103/248 (41%), Positives = 143/248 (57%), Gaps = 10/248 (4%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GG A +WPWQVS+ G +H CGGSL+ QWVL+AAHC P A V+L Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCF-PSEHHKEAYEVKL 56 Query: 91 REQHL--YYQD-QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L Y +D ++ + II HP + DIALL+L P+ S ++ ++LP A Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQA 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 +FP G+ C VTGWG V L P PL+Q++VP++ C++ Y++ A ++ V++ Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKP-EEPHFVQE 175 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 DM+CAG +D+CQGDSGGPL C V G W G+VSWG+ C NRPG+YT + Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 235 Query: 266 WIHHYVPK 273 WI V + Sbjct: 236 WIQSKVTE 243 >2F83-A nrPDB Length = 625 Score = 181 bits (460), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 99/242 (40%), Positives = 130/242 (53%), Gaps = 16/242 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ- 89 IVGG + R +WPWQV+L P H CGGS+I QW+LTAAHC V+ LRV Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCF-YGVESPKILRVYS 446 Query: 90 --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + + V II+H Q+ A+ G DIALL+LE VN + + LP + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 CWVTGWG +++ L++ K+P++ N C +Y T Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNT--LQKAKIPLVTNEECQKRYRGHKIT--------H 556 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M+CAG +D+C+GDSGGPL CK N W G+ SWGEGCAQ RPG+YT V Y+D Sbjct: 557 KMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616 Query: 266 WI 267 WI Sbjct: 617 WI 618 >6AOD-C nrPDB Length = 245 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 97/242 (40%), Positives = 131/242 (54%), Gaps = 16/242 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ- 89 IVGG + R +WPWQV+L P H CGGS+I QW+LTAAHC V+ LRV Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCF-YGVESPKILRVYS 59 Query: 90 --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L++ + V II+H Q+ A+ G DIALL+LE V + ++LP + Sbjct: 60 GILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 CWVTGWG +++ L++ K+P++ N C +Y T Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNT--LQKAKIPLVTNEECQKRYRGHKIT--------H 169 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M+CAG +D+C+GD+GGPL CK N W G+ SWGEGCAQ RPG+YT V Y+D Sbjct: 170 KMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 229 Query: 266 WI 267 WI Sbjct: 230 WI 231 >5TJX-A nrPDB Length = 263 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 97/241 (40%), Positives = 139/241 (57%), Gaps = 14/241 (5%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89 IVGG E+ +WPWQVSL+V H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 16 IVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 75 Query: 90 LREQHLYYQDQ-LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + E +D + II+H + ++ DIAL++L+ P+ + ++LP +T Sbjct: 76 ILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKGDT 135 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 CWVTGWG + E+ L++V +P++ N C +Y D +I + Sbjct: 136 STIYTNCWVTGWGF--SKEKGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 185 Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 M+CAG +D+C+GDSGGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+DW Sbjct: 186 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 245 Query: 267 I 267 I Sbjct: 246 I 246 >5GVT-A nrPDB Length = 250 Score = 175 bits (444), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 98/246 (39%), Positives = 138/246 (56%), Gaps = 24/246 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG----PDVKDLAAL 86 IVGG A +WPWQVSL+V H CGGS+I QWVLTAAHC PDV + Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 87 RVQLREQHLYYQDQLLPVSRI---IVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP 143 + L E + P SRI I+H ++ ++ DIAL++L+ P+N + ++LP Sbjct: 61 ILSLSEI-----TKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLP 115 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 ++T CWVTGWG E+ L++ +P++ N C KY Sbjct: 116 SKADTNTIYTNCWVTGWGYTK--EQGETQNILQKATIPLVPNEECQKKYR--------DY 165 Query: 204 IVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 ++ M+CAG D+C+GDSGGPLVCK +G W G+ SWGEGCA+ ++PG+YT+V+ Sbjct: 166 VINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVS 225 Query: 262 YYLDWI 267 Y+DWI Sbjct: 226 EYMDWI 231 >6I44-A nrPDB Length = 627 Score = 171 bits (432), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 94/241 (39%), Positives = 137/241 (56%), Gaps = 14/241 (5%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89 IVGG ++ +WPWQVSL+V H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 380 IVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 439 Query: 90 LREQHLYYQDQ-LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D + II+H + ++ DIAL++L+ P+ + + LP +T Sbjct: 440 ILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSKGDT 499 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 CWVTGWG + E L++V +P++ N C +Y D +I + Sbjct: 500 STIYTNCWVTGWGF--SAEAGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 549 Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 M+CAG +D+C+GD+GGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+DW Sbjct: 550 MVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 609 Query: 267 I 267 I Sbjct: 610 I 610 >2CGA-A nrPDB Length = 245 Score = 171 bits (432), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 91/241 (37%), Positives = 129/241 (53%), Gaps = 14/241 (5%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IV G+EA WPWQVSL+ + HFCGGSLI+ WV+TAAHC G D+ + + Sbjct: 16 IVNGEEAVPGSWPWQVSLQDKTGF--HFCGGSLINENWVVTAAHC-GVTTSDVV-VAGEF 71 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + + Q L ++++ + ++ + I DI LL+L + S V V LP AS+ F Sbjct: 72 DQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 131 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C TGWG + P L+Q +P++ N C K + G ++D M+ Sbjct: 132 AGTTCVTTGWG-LTRYTNANTPDRLQQASLPLLSNTNC--KKYWGTK-------IKDAMI 181 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CAG + SC GDSGGPLVCK NG W G+VSWG + PG+Y RVT ++W+ Sbjct: 182 CAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQT 241 Query: 271 V 271 + Sbjct: 242 L 242 >2V35-A nrPDB Length = 240 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 96/253 (37%), Positives = 140/253 (55%), Gaps = 22/253 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVH-GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG EA R+ WP Q+SL+ G W H CGG+LI WV+TAAHCV ++ RV Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDREL----TFRVV 56 Query: 90 LREQHLYYQD---QLLPVSRIIVHPQFYTAQIGA--DIALLELEEPVNVSSHVHTVTLPP 144 + E +L D Q + V +I+VHP + T + A DIALL L + V ++S+V LP Sbjct: 57 VGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPR 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A PC++TGWG + +L L+Q +P ++ IC + + G+ Sbjct: 117 AGTILANNSPCYITGWGLTRTNGQLAQ--TLQQAYLPTVDYAICSSSSYWGS-------T 167 Query: 205 VRDDMLCA-GNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE--GCAQPNRPGIYTRVT 261 V++ M+CA G+ R CQGDSGGPL C VNG + GV S+ GC +P ++TRV+ Sbjct: 168 VKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVS 227 Query: 262 YYLDWIHHYVPKK 274 Y+ WI++ + Sbjct: 228 AYISWINNVIASN 240 >5FXL-A nrPDB Length = 246 Score = 161 bits (408), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 92/249 (36%), Positives = 138/249 (55%), Gaps = 31/249 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 24 IVGGYTCGANTVPYQVSLNSG----YHFCGGSLINSQWVVSAAHCY------KSGIQVRL 73 Query: 91 REQHLYY---QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E ++ +Q + S+ IVHP + + + DI L++L+ +++S V +++LP + Sbjct: 74 GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA 133 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 + G C ++GWG+ + P LK +K PI+ + C + AY G + Sbjct: 134 S--AGTQCLISGWGNTKSSGTSYPDV-LKCLKAPILSDSSCKS-----AYPGQ----ITS 181 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M CAG +DSCQGDSGGP+VC LQ G+VSWG GCAQ N+PG+YT+V Y+ Sbjct: 182 NMFCAGYLEGGKDSCQGDSGGPVVCSGK---LQ-GIVSWGSGCAQKNKPGVYTKVCNYVS 237 Query: 266 WIHHYVPKK 274 WI + Sbjct: 238 WIKQTIASN 246 >4AN7-A nrPDB Length = 231 Score = 160 bits (405), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 96/246 (39%), Positives = 138/246 (56%), Gaps = 31/246 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 9 IVGGYTCAANSIPYQVSLNSGS----HFCGGSLINSQWVVSAAHCY------KSRIQVRL 58 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP F + DI L++L P ++S V TV+LP + Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C ++GWG+ + P L+ +K P++ + C + Y G TG+ Sbjct: 119 A--AGTECLISGWGNTKSSGSSYPSL-LQCLKAPVLSDSSCKSSYP-GQITGN------- 167 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M+C G +DSCQGDSGGP+VC NG LQ G+VSWG GCAQ N+PG+YT+V Y++ Sbjct: 168 -MICVGFLEGGKDSCQGDSGGPVVC--NGQ-LQ-GIVSWGYGCAQKNKPGVYTKVCNYVN 222 Query: 266 WIHHYV 271 WI + Sbjct: 223 WIQQTI 228 >5UGG-A nrPDB Length = 251 Score = 159 bits (401), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 94/242 (38%), Positives = 129/242 (53%), Gaps = 22/242 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 +VGG A WPWQVSLR + MHFCGG+LI P+WVLTAAHC+ P + Sbjct: 22 VVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 79 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 +E +L Q + VSR+ + P DIALL+L P ++ V LP + Sbjct: 80 AHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSPNYV 133 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 C++TGWG+ LK+ ++P++EN +C+ L V+ Sbjct: 134 VADRTECFITGWGETQGTFGAGL---LKEAQLPVIENKVCNRYEFLNGR-------VQST 183 Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 LCAG+ DSCQGDSGGPLVC ++ GV SWG GCA+PN+PG+Y RV+ ++ W Sbjct: 184 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 243 Query: 267 IH 268 I Sbjct: 244 IE 245 >2TLD-E nrPDB Length = 220 Score = 157 bits (398), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 91/247 (36%), Positives = 137/247 (55%), Gaps = 30/247 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 1 IVGGYTCGANTVPYQVSLNSG----YHFCGGSLINSQWVVSAAHCY------KSGIQVRL 50 Query: 91 REQHLYY---QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E ++ +Q + S+ IVHP + + + DI L++L+ +++S V +++LP + Sbjct: 51 GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA 110 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 + G C ++GWG+ + P LK +K PI+ + C + AY G + Sbjct: 111 S--AGTQCLISGWGNTKSSGTSYPDV-LKCLKAPILSDSSCKS-----AYPGQ----ITS 158 Query: 208 DMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +M CAG DSCQGDSGGP+VC LQ G+VSWG GCA+ N+PG+YT+V Y+ WI Sbjct: 159 NMFCAGLEGGDSCQGDSGGPVVCSGK---LQ-GIVSWGSGCAK-NKPGVYTKVCNYVSWI 213 Query: 268 HHYVPKK 274 + Sbjct: 214 KQTIASN 220 >3P8G-A nrPDB Length = 241 Score = 156 bits (395), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 98/250 (39%), Positives = 129/250 (51%), Gaps = 24/250 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD--------VKD 82 +VGG +A +WPWQVSL G H CG SLI P W+++AAHC D + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQ--GHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142 A L + + Q Q + RII HP F DIALLELE+P SS V + L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P AS FP G WVTGWG L++ ++ +++ C+ Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGG--TGALILQKGEIRVIQQTTCENLLP--------- 167 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRPGIYTR 259 + + M+C G + DSCQGDSGGPL + +G QAGVVSWG+GCAQ N+PG+YTR Sbjct: 168 QQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTR 227 Query: 260 VTYYLDWIHH 269 + + DWI Sbjct: 228 LPLFRDWIKE 237 >4DUR-A nrPDB Length = 791 Score = 156 bits (394), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 94/242 (38%), Positives = 129/242 (53%), Gaps = 22/242 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 +VGG A WPWQVSLR + MHFCGG+LI P+WVLTAAHC+ P + Sbjct: 562 VVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 619 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 +E +L Q + VSR+ + P DIALL+L P ++ V LP + Sbjct: 620 AHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSPNYV 673 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 C++TGWG+ LK+ ++P++EN +C+ L V+ Sbjct: 674 VADRTECFITGWGETQGTFGA---GLLKEAQLPVIENKVCNRYEFLNGR-------VQST 723 Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 LCAG+ DSCQGDSGGPLVC ++ GV SWG GCA+PN+PG+Y RV+ ++ W Sbjct: 724 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 783 Query: 267 IH 268 I Sbjct: 784 IE 785 >1ELT-A nrPDB Length = 236 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 88/246 (35%), Positives = 133/246 (54%), Gaps = 21/246 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVH-GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG+ A + WPWQ+SL+ G + H CGGSLI WV+TAAHCV RV Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCV----DSARTWRVV 56 Query: 90 LREQHLYY---QDQLLPVSRIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPP 144 L E +L ++Q++ V+ + +H + + + G DIALL L +++S V LPP Sbjct: 57 LGEHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPP 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 +++ P PC++TGWG P LKQ +P +++ C + G+ Sbjct: 117 SNQILPNNNPCYITGWGKTSTGG--PLSDSLKQAWLPSVDHATCSSSGWWGS-------T 167 Query: 205 VRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVTY 262 V+ M+CAG C GDSGGPL C+VNG++ GV S+ GC +P ++TRV+ Sbjct: 168 VKTTMVCAGGGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSA 227 Query: 263 YLDWIH 268 Y+ W++ Sbjct: 228 YISWMN 233 >1A0J-A nrPDB Length = 223 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 94/242 (38%), Positives = 138/242 (57%), Gaps = 31/242 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E ++ +Q SL+ HFCGGSLI WV++AAHC + ++V+L Sbjct: 1 IVGGYECRKNSASYQASLQSG----YHFCGGSLISSTWVVSAAHCY------KSRIQVRL 50 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E ++ + Q + ++I+HP + + + DI L++L +P +++S+V TV LP S Sbjct: 51 GEHNIAVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALP--SS 108 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C V+GWG++ P L+ + +PI+ + C++ AY G + Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPD-TLRCLDLPILSSSSCNS-----AYPGQ----ITS 158 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M CAG +DSCQGDSGGP+VC NG LQ GVVSWG GCAQ N+PG+YT+V Y Sbjct: 159 NMFCAGFMEGGKDSCQGDSGGPVVC--NGQ-LQ-GVVSWGYGCAQRNKPGVYTKVCNYRS 214 Query: 266 WI 267 WI Sbjct: 215 WI 216 >1F7Z-A nrPDB Length = 233 Score = 155 bits (391), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 96/246 (39%), Positives = 136/246 (55%), Gaps = 31/246 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 11 IVGGYTCQENSVPYQVSLN----SGYHFCGGSLINDQWVVSAAHCYK------SRIQVRL 60 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP F + DI L++L PV +++ V TV LP S Sbjct: 61 GEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALP--SS 118 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P G C ++GWG+ + P L+ + P++ C+A Y + D Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDL-LQCLDAPLLPQADCEASYP---------GKITD 168 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M+C G +DSCQGDSGGP+VC NG LQ G+VSWG GCA P+ PG+YT+V Y+D Sbjct: 169 NMVCVGFLEGGKDSCQGDSGGPVVC--NGE-LQ-GIVSWGYGCALPDNPGVYTKVCNYVD 224 Query: 266 WIHHYV 271 WI + Sbjct: 225 WIQDTI 230 >2F91-A nrPDB Length = 237 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 88/244 (36%), Positives = 133/244 (54%), Gaps = 19/244 (7%) Query: 31 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRV 88 IVGG +A ++P+Q+S + + HFCG S+ + + +TA HCV G D ++ + L++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 89 QLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 E + + Q++ VS+II+H F + DI+LL+L + + +V + LP Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 T + VTGWG E P L++V VP++ + C A Y + Sbjct: 121 GHTATGDV--IVTGWGTTS--EGGNTPDVLQKVTVPLVSDEDCRADYG--------ADEI 168 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 D M+CAG +DSCQGDSGGPL G+ AG+VSWG GCA+P PG+YT V+Y+ Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYH 228 Query: 264 LDWI 267 +DWI Sbjct: 229 VDWI 232 >4DGJ-A nrPDB Length = 235 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 131/247 (53%), Gaps = 19/247 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDV---KDLAAL 86 IVGG +A WPW V L CG SL+ W+++AAHCV G ++ K A L Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRL---LCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + ++ Q + I+++P + + DIA++ LE VN + ++ ++LP + Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FPPG C + GWG V L++ VP++ N C + + Y + Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADI--LQEADVPLLSNERC--QQQMPEYN------IT 167 Query: 207 DDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M+CAG DSCQGDSGGPL+C+ N W AGV S+G CA PNRPG+Y RV+ + Sbjct: 168 ENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFT 227 Query: 265 DWIHHYV 271 +WI ++ Sbjct: 228 EWIQSFL 234 >3F6U-H nrPDB Length = 240 Score = 150 bits (379), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 90/251 (35%), Positives = 128/251 (50%), Gaps = 23/251 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAAL-RVQ 89 ++ G+ R PWQV L CG LIHP WVLTAAHC+ K L L Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLA--CGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD 58 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS--- 146 LR + D L + + VHP + + DIALL L +P +S + + LP + Sbjct: 59 LRRWEKWELD--LDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAE 116 Query: 147 -ETFPPGMPCWVTGWG---DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 E G VTGWG + + + F L +K+P++ ++ C Sbjct: 117 RELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMS--------- 167 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260 +V ++MLCAG R+D+C+GDSGGP+V +GTW G+VSWGEGC + G+YT+V Sbjct: 168 NMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKV 227 Query: 261 TYYLDWIHHYV 271 + YLDWIH ++ Sbjct: 228 SRYLDWIHGHI 238 >4WWY-A nrPDB Length = 224 Score = 150 bits (378), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 94/248 (37%), Positives = 138/248 (55%), Gaps = 35/248 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++A HC + ++V+L Sbjct: 1 IVGGYNCEENSVPYQVSLNSG----YHFCGGSLINEQWVVSAGHCY------KSRIQVRL 50 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HPQ+ + DI L++L +++HV T++LP A Sbjct: 51 GEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA-- 108 Query: 148 TFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 PP G C ++GWG+ + P L+ + P++ C+A +Y G + Sbjct: 109 --PPATGTKCLISGWGNTASS-GADYPDELQCLDAPVLSQAKCEA-----SYPGK----I 156 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 +M C G +DSCQ DSGGP+VC NG LQ GVVSWG+GCAQ N+PG+YT+V Y Sbjct: 157 TSNMFCVGFLEGGKDSCQRDSGGPVVC--NGQ-LQ-GVVSWGDGCAQKNKPGVYTKVYNY 212 Query: 264 LDWIHHYV 271 + WI + + Sbjct: 213 VKWIKNTI 220 >1EKB-B nrPDB Length = 235 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 85/247 (34%), Positives = 132/247 (53%), Gaps = 19/247 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDV---KDLAAL 86 IVGG ++ WPW V+L CG SL+ W+++AAHCV G ++ K A L Sbjct: 1 IVGGSDSREGAWPWVVALYFDD---QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + + Q + + +I+++P + + DIA++ LE VN + ++ + LP + Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FPPG C + GWG + L++ VP++ N C + + Y + Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADV--LQEADVPLLSNEKC--QQQMPEYN------IT 167 Query: 207 DDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M+CAG DSCQGDSGGPL+C+ N WL AGV S+G CA PNRPG+Y RV + Sbjct: 168 ENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFT 227 Query: 265 DWIHHYV 271 +WI ++ Sbjct: 228 EWIQSFL 234 >2OQ5-A nrPDB Length = 232 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 97/243 (39%), Positives = 133/243 (54%), Gaps = 23/243 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP---DVKDLAALR 87 IVGG E +WPWQ SL+ G H CG +LI+ W+++AAHC + A+ Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGS---HRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 V ++ + + RIIVH ++ DI+L EL PV ++ VH V LP AS Sbjct: 58 VTIKPSKMKRG-----LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY 112 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 F PG +VTG+G + ND L+Q +V +++ C+ AY +D R Sbjct: 113 EFQPGDVMFVTGFGALKNDGY--SQNHLRQAQVTLIDATTCNEPQ---AY--NDAITPR- 164 Query: 208 DMLCAGNT--RRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 MLCAG+ + D+CQGDSGGPLV W AG+VSWG+ CA+PN+PG+YTRVT Sbjct: 165 -MLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALR 223 Query: 265 DWI 267 DWI Sbjct: 224 DWI 226 >3W94-A nrPDB Length = 235 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 93/243 (38%), Positives = 124/243 (51%), Gaps = 19/243 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDL----AAL 86 +VGG A + WPW VSL G H CG SLI W+LTAAHCV L A L Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRG---RHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + + + Q+ V RII++ + ADIA++ L++PVN + V V L Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FP G C++ GWG LP L++ +VP+++ C + L YT Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDI--LQEAEVPLVDQDEC--QRLLPEYT------FT 167 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 MLCAG DSCQGDSGGPL+C + W GV S+G GC +P RPG Y RV+ + Sbjct: 168 SSMLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFT 227 Query: 265 DWI 267 WI Sbjct: 228 SWI 230 >1PYT-D nrPDB Length = 251 Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 87/247 (35%), Positives = 132/247 (53%), Gaps = 21/247 (8%) Query: 31 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG++A WPWQ+SL+ + W H CGG+LI P VLTAAHC+ + RV Sbjct: 14 VVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI----SNTLTYRVA 69 Query: 90 LREQHLYYQDQ----LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 L + +L +D+ + V I VH ++ + + DIAL++L E V + + LP Sbjct: 70 LGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSE 129 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 P PC+VTGWG + + P L+Q P+++ C + G V Sbjct: 130 GSLLPQDYPCFVTGWGRLYTNG--PIAAELQQGLQPVVDYATCSQRDWWGT-------TV 180 Query: 206 RDDMLCA-GNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG--CAQPNRPGIYTRVTY 262 ++ M+CA G+ +C GDSGGPL C+ +G W G+VS+G G C +P ++TRV+ Sbjct: 181 KETMVCAGGDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSA 240 Query: 263 YLDWIHH 269 Y+DWI+ Sbjct: 241 YIDWINQ 247 >1BRU-P nrPDB Length = 241 Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 90/254 (35%), Positives = 136/254 (53%), Gaps = 23/254 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGP-YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG++A + WPWQVSL+ W H CGG+L+ WVLTAAHC+ RV Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS----RTYRVV 56 Query: 90 LREQHLYYQD---QLLPVSRIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPP 144 L L + + VS+++VH + + Q+ G DIALL+L PV+++ + LP Sbjct: 57 LGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPA 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A P C+VTGWG + + P L+Q ++ +++ C G+ Sbjct: 117 AGTILPNNYVCYVTGWGRLQTNG--ASPDILQQGQLLVVDYATCSKPGWWGS-------T 167 Query: 205 VRDDMLCA-GNTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGE--GCAQPNRPGIYTRV 260 V+ +M+CA G+ SC GDSGGPL C+ NG W G+VS+G GC ++P ++TRV Sbjct: 168 VKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRV 227 Query: 261 TYYLDWIHHYVPKK 274 + Y+DWI+ + Sbjct: 228 SNYIDWINSVIANN 241 >1UTJ-A nrPDB Length = 242 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 90/240 (37%), Positives = 129/240 (53%), Gaps = 28/240 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRVQ 89 IVGG E P QVSL HFCGGSL++ WV++AAHC V+ L ++ Sbjct: 21 IVGGYECKPYSQPHQVSLNSG----YHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIK 76 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + E +Q + SR+I HP + + I DI L++L +P ++++V V LP + Sbjct: 77 VTEG----SEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTSCA-- 130 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 P G C V+GWG+ + L+ + +PI+ C+ Y ++ + M Sbjct: 131 PAGTMCTVSGWGNTMSST--ADSNKLQCLNIPILSYSDCNNSYP---------GMITNAM 179 Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG +DSCQGDSGGP+VC NG LQ GVVSWG GCA+P PG+Y +V + DW+ Sbjct: 180 FCAGYLEGGKDSCQGDSGGPVVC--NGE-LQ-GVVSWGYGCAEPGNPGVYAKVCIFNDWL 235 >3T2N-A nrPDB Length = 372 Score = 145 bits (365), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 92/260 (35%), Positives = 130/260 (50%), Gaps = 37/260 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88 IVGG++ +WPWQVSLR G H CGGSL+ WVLTAAHC + L+ RV Sbjct: 118 IVGGRDTSLGRWPWQVSLRYDGA---HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 174 Query: 89 -----------QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHV 137 QL Q + Y LP P + + DIAL+ L P+ ++ ++ Sbjct: 175 GAVAQASPHGLQLGVQAVVYHGGYLPFR----DPN--SEENSNDIALVHLSSPLPLTEYI 228 Query: 138 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 V LP A + G C VTGWG+ + L++ +VPI+ N +C+ G Sbjct: 229 QPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV--LQEARVPIISNDVCNGADFYGNQ 286 Query: 198 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT----WLQAGVVSWGEGCAQP 251 ++ M CAG D+CQGDSGGP VC+ + + W G+VSWG GCA Sbjct: 287 -------IKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALA 339 Query: 252 NRPGIYTRVTYYLDWIHHYV 271 +PG+YT+V+ + +WI + Sbjct: 340 QKPGVYTKVSDFREWIFQAI 359 >1P57-B nrPDB Length = 255 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 92/260 (35%), Positives = 130/260 (50%), Gaps = 37/260 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88 IVGG++ +WPWQVSLR G H CGGSL+ WVLTAAHC + L+ RV Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDG---AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 89 -----------QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHV 137 QL Q + Y LP P + + DIAL+ L P+ ++ ++ Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFR----DPN--SEENSNDIALVHLSSPLPLTEYI 111 Query: 138 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 V LP A + G C VTGWG+ + L++ +VPI+ N +C+ G Sbjct: 112 QPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV--LQEARVPIISNDVCNGADFYG-- 167 Query: 198 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT----WLQAGVVSWGEGCAQP 251 ++ M CAG D+CQGDSGGP VC+ + + W G+VSWG GCA Sbjct: 168 -----NQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALA 222 Query: 252 NRPGIYTRVTYYLDWIHHYV 271 +PG+YT+V+ + +WI + Sbjct: 223 QKPGVYTKVSDFREWIFQAI 242 >1FIW-A nrPDB Length = 290 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 89/258 (34%), Positives = 135/258 (52%), Gaps = 27/258 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 I+GGQ+A WPW VSL++ H H CGGSL++ QW+LTAAHC K + R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIK-KKVTDWR 59 Query: 88 VQLREQHLYYQD--------QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHT 139 + + + + Q V +II+H ++ + DIAL+++ PV + Sbjct: 60 LIFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGP 119 Query: 140 VTLPPASETFPPGMP--CWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 LP PP +P CWV GWG + + R P L++ +V +++ +C++ Y Sbjct: 120 GCLP-QFRAGPPRVPQTCWVAGWGFLQENARRTSPM-LQEARVDLIDLGLCNSTRW---Y 174 Query: 198 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGEGCAQPNR 253 G +R +CAG + D+CQGDSGGPL+CK +++ G+ SWG GCA+ R Sbjct: 175 NGR----IRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKR 230 Query: 254 PGIYTRVTYYLDWIHHYV 271 PG+YT YL+WI + Sbjct: 231 PGVYTSTWSYLNWIASKI 248 >5C67-A nrPDB Length = 224 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 95/250 (38%), Positives = 132/250 (52%), Gaps = 39/250 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI QWV++AAHC ++ V+L Sbjct: 1 IVGGYTCEENSLPYQVSLNSGS----HFCGGSLISEQWVVSAAHCYKTRIQ------VRL 50 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP++ + DI L++L P +++ V T++LP A Sbjct: 51 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA-- 108 Query: 148 TFPP--GMPCWVTGWGDVDNDERLPPPFP--LKQVKVPIMENHICDAKYHLGAYTGDDVR 203 PP G C ++GWG N +P LK + P++ C A Y Sbjct: 109 --PPAAGTECLISGWG---NTLSFGADYPDELKCLDAPVLTQAECKASYP---------G 154 Query: 204 IVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 + + M C G +DSCQ D+GGP+VC NG LQ GVVSWG GCA NRPG+YT+V Sbjct: 155 KITNSMFCVGFLEGGKDSCQRDAGGPVVC--NGQ-LQ-GVVSWGHGCAWKNRPGVYTKVY 210 Query: 262 YYLDWIHHYV 271 Y+DWI + Sbjct: 211 NYVDWIKDTI 220 >3LC3-A nrPDB Length = 235 Score = 143 bits (361), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 88/243 (36%), Positives = 133/243 (54%), Gaps = 21/243 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG++A ++PWQV L FCGGS+++ +W++TAAHCV VK + + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVD---AFCGGSIVNEKWIVTAAHCVETGVK-ITVVAGEH 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTA--QIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +Q V RII H + A + DIALLEL+EP+ ++S+V + + T Sbjct: 57 NIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYT 116 Query: 149 --FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 F +V+GWG V + R L+ ++VP+++ C Y Sbjct: 117 NIFLKFGSGYVSGWGRVFHKGR--SALVLQYLRVPLVDRATCLRSTKFTIY--------- 165 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M CAG RDSCQGDSGGP V +V GT G++SWGE CA + GIYT+V+ Y+ Sbjct: 166 NNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYV 225 Query: 265 DWI 267 +WI Sbjct: 226 NWI 228 >1X7A-C nrPDB Length = 235 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 92/246 (37%), Positives = 131/246 (53%), Gaps = 23/246 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ A ++PWQV L FCGGS+I+ +WV+TAAHC+ P VK + + + Sbjct: 1 IVGGENAKPGQFPWQVLLN---GKIDAFCGGSIINEKWVVTAAHCIEPGVK-ITVVAGEY 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGA---DIALLELEEPVNVSSHVHTVTLPPASE 147 + +Q V R I H Y A + DIALLEL+EP+ ++S+V + + Sbjct: 57 NTEETEPTEQRRNVIRAIPHHS-YNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 148 T--FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 T F +V+GWG V N R L+ +KVP+++ C Y+ Sbjct: 116 TNIFLKFGSGYVSGWGRVFNRGR--SATILQYLKVPLVDRATCLRSTKFTIYS------- 166 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 +M CAG +DSCQGDSGGP V +V GT G++SWGE CA + GIYT+V+ Y Sbjct: 167 --NMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRY 224 Query: 264 LDWIHH 269 ++WI Sbjct: 225 VNWIKE 230 >4H4F-A nrPDB Length = 249 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 133/248 (53%), Gaps = 22/248 (8%) Query: 31 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG++A WPWQ+SL+ + W H CGG+LI +VLTAAHC+ + RV Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----SNTRTYRVA 56 Query: 90 LREQHLYYQDQ----LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 + + +L +D+ + V I VH ++ + DIAL++L E V +S + LP Sbjct: 57 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 116 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 P PC+VTGWG + + P L+Q P++++ C G V Sbjct: 117 DSLLPKDYPCYVTGWGRLWTNG--PIADKLQQGLQPVVDHATCSRIDWWGFR-------V 167 Query: 206 RDDMLCA-GNTRRDSCQGDSGGPLVCKV-NGTWLQAGVVSWG--EGCAQPNRPGIYTRVT 261 + M+CA G+ +C GDSGGPL C++ NG+W G+VS+G GC +P +YTRV+ Sbjct: 168 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 262 YYLDWIHH 269 Y+DWI+ Sbjct: 228 AYIDWINE 235 >2EEK-A nrPDB Length = 220 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 126/242 (52%), Gaps = 32/242 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + QVSL HFCGGSL+ WV++AAHC + LRV+L Sbjct: 1 IVGGYECTKHSQAHQVSLNS----GYHFCGGSLVSKDWVVSAAHCY------KSVLRVRL 50 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E H+ + Q + S +I HP + + I DI L++L +P ++ +VH V LP +E Sbjct: 51 GEHHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALP--TE 108 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 C V+GWG+ + + L+ + +PI+ + C Y ++ Sbjct: 109 CAADATMCTVSGWGNTMSS--VADGDKLQCLSLPILSHADCANSY---------PGMITQ 157 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M CAG +DSCQGDSGGP+VC NG LQ GVVSWG GCA+ + PG+Y +V Sbjct: 158 SMFCAGYLEGGKDSCQGDSGGPVVC--NGV-LQ-GVVSWGYGCAERDHPGVYAKVCVLSG 213 Query: 266 WI 267 W+ Sbjct: 214 WV 215 >1BDA-A nrPDB Length = 265 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 94/256 (36%), Positives = 126/256 (49%), Gaps = 29/256 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 I GG A + PWQ ++ P CGG LI W+L+AAHC Sbjct: 14 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTV 73 Query: 88 VQLREQHLY--YQDQLLPVSRIIVHPQFYTAQIGADIALLELEEP----VNVSSHVHTVT 141 + R + ++Q V + IVH +F DIALL+L+ SS V TV Sbjct: 74 ILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVC 133 Query: 142 LPPASETFPPGMPCWVTGWGDVDNDERLPPPFP--LKQVKVPIMENHICDAKYHLGAYTG 199 LPPA P C ++G+G E L P + LK+ V + + C +++ L Sbjct: 134 LPPADLQLPDWTECELSGYG---KHEALSPFYSERLKEAHVRLYPSSRCTSQHLLN---- 186 Query: 200 DDVRIVRDDMLCAGNTR--------RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQP 251 R V D+MLCAG+TR D+CQGDSGGPLVC +G G++SWG GC Q Sbjct: 187 ---RTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQK 243 Query: 252 NRPGIYTRVTYYLDWI 267 + PG+YT+VT YLDWI Sbjct: 244 DVPGVYTKVTNYLDWI 259 >4Z6A-H nrPDB Length = 249 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 89/253 (35%), Positives = 130/253 (51%), Gaps = 23/253 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ P+ + PWQV L V+G CGG+LI+ WV++AAHC +K+ L L Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGA---QLCGGTLINTIWVVSAAHCF-DKIKNWRNLIAVL 56 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP--- 144 E L D Q V+++I+ + DIALL L +PV ++ HV + LP Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 + T V+GWG + +R L + VP + C+A +Y G Sbjct: 117 SERTLAFVRFSLVSGWGQLL--DRGATALELMVLNVPRLMTQDCEA-----SYPGK---- 165 Query: 205 VRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + + M CAG + +DSC+GDSGGP GTW G+VSWG+GCA G+YTRV+ Sbjct: 166 ITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQ 225 Query: 263 YLDWIHHYVPKKP 275 Y++W+ + +P Sbjct: 226 YIEWLQKLMRSEP 238 >4NFE-A nrPDB Length = 237 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 94/262 (35%), Positives = 132/262 (50%), Gaps = 42/262 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQV++ HG W H CGG L+HPQWVLTAAHC+ + + V L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHG--WAH-CGGVLVHPQWVLTAAHCLKKNSQ------VWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSH 136 +L+ + Q +PVS HP + + + D+ LL L EP ++ Sbjct: 52 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 112 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFL-RPRSLQCVSLHLLSNDMCARAYS--- 165 Query: 197 YTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 253 V + MLCAG +D+C GDSGGPLVC NG + G+ SWG E CA P + Sbjct: 166 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NG--VLQGITSWGPEPCALPEK 215 Query: 254 PGIYTRVTYYLDWIHHYVPKKP 275 P +YT+V +Y WI + P Sbjct: 216 PAVYTKVVHYRKWIKDTIAANP 237 >1MKW-K nrPDB Length = 308 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 92/266 (34%), Positives = 132/266 (49%), Gaps = 33/266 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-------GPDVKDL 83 IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ V DL Sbjct: 50 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 84 -AALRVQLREQHLYYQDQLLPVSRIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 + R ++ +++ + +I +HP++ + + DIALL+L+ P+ +S ++H V Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 142 LP---PASETFPPGMPCWVTGWGDVDNDERLP----PPFPLKQVKVPIMENHICDAKYHL 194 LP A++ G VTGWG+ P L+ V +P++E +C A Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR- 227 Query: 195 GAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGEG 247 +RI D+M CAG R D+C+GDSGGP V K N W Q G+VSWGEG Sbjct: 228 -------IRIT-DNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG 279 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVPK 273 C + + G YT V WI + + Sbjct: 280 CDRDGKYGFYTHVFRLKKWIQKVIDR 305 >1ETT-H nrPDB Length = 259 Score = 134 bits (337), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 92/266 (34%), Positives = 132/266 (49%), Gaps = 33/266 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-------GPDVKDL 83 IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ V DL Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 84 -AALRVQLREQHLYYQDQLLPVSRIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 + R ++ +++ + +I +HP++ + + DIALL+L+ P+ +S ++H V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDVDNDERLP----PPFPLKQVKVPIMENHICDAKYHL 194 LP A++ G VTGWG+ P L+ V +P++E +C A Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR- 178 Query: 195 GAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGEG 247 +RI D+M CAG R D+C+GDSGGP V K N W Q G+VSWGEG Sbjct: 179 -------IRIT-DNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG 230 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVPK 273 C + + G YT V WI + + Sbjct: 231 CDRDGKYGFYTHVFRLKKWIQKVIDR 256 >5LHN-A nrPDB Length = 247 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 85/254 (33%), Positives = 128/254 (50%), Gaps = 21/254 (8%) Query: 31 IVGGQEAPRSKWPWQVSL--RVHGPYWMHF-CGGSLIHPQWVLTAAHCVG--PDVKDLAA 85 IVGG+ PW ++ + G F CGGSLI P WV +AAHC P ++ Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEPVNV----SSHVHT 139 Q +E + V ++I+H + + DIALL++ S + T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 199 + LPP P G C +TG+G + L P LK V ++ + C ++ G+ Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPK-NLKMSVVKLVSHEQCMQPHYYGSE-- 177 Query: 200 DDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIY 257 + MLCA + + DSC+GDSGGPL+C + G +G+VSWG GCA+ N+PG+Y Sbjct: 178 -----INYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVY 232 Query: 258 TRVTYYLDWIHHYV 271 TRV+++LDWI ++ Sbjct: 233 TRVSHFLDWIQSHI 246 >1AZZ-A nrPDB Length = 226 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 94/249 (37%), Positives = 125/249 (50%), Gaps = 27/249 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89 IVGG EA + WP Q +L + M+FCGGSLI P+W+LTAAHC+ G D+ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHN 57 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 +RE + + VH + + I DIA++ L PV +++ + TV LP S Sbjct: 58 IREDEA--TQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLP--STDV 113 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 G TGWG + +D L L+QV VPIM N CDA Y IV D Sbjct: 114 GVGTVVTPTGWG-LPSDSALGISDVLRQVDVPIMSNADCDAVY----------GIVTDGN 162 Query: 210 LCAGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVTYYLDW 266 +C +T + +C GDSGGPL N L G+ S+G GC + P +TRVTY+LDW Sbjct: 163 ICIDSTGGKGTCNGDSGGPL----NYNGLTYGITSFGAAAGC-EAGYPDAFTRVTYFLDW 217 Query: 267 IHHYVPKKP 275 I P Sbjct: 218 IQTQTGITP 226 >2OCV-B nrPDB Length = 259 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 93/265 (35%), Positives = 134/265 (50%), Gaps = 35/265 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--------GPDVKD 82 IV G +A + PWQV L P + CG SLI +WVLTAAHC+ + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I VHP++ + + DIALL+L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDV-----DNDERLPPPFPLKQVKVPIMENHICDAKYH 193 LP + G VTGWG++ N + P L+ V +PI+E +C A Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSV-LQVVNLPIVERPVCKASTR 178 Query: 194 LGAYTGDDVRIVRDDMLCAG----NTRR-DSCQGDSGGPLVCK--VNGTWLQAGVVSWGE 246 +RI D+M CAG +T+R D+C+GDSGGP V K N W Q G+VSWGE Sbjct: 179 --------IRIT-DNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 229 Query: 247 GCAQPNRPGIYTRVTYYLDWIHHYV 271 GC + + G YT V WI + Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >1FIZ-A nrPDB Length = 263 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 132/259 (50%), Gaps = 29/259 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 +VGG A WPW VSL++ H H CGG L++ WVLTAAHC + K + R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCF-KNKKKVTDWR 59 Query: 88 VQLREQHLYYQD--------QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHT 139 + + + Q V II+H ++ + DIAL+++ PV + Sbjct: 60 LIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGP 119 Query: 140 VTLPPASETFPPGMP--CWVTGWGDVDNDERLPPPFP-LKQVKVPIMENHICDAKYHLGA 196 LP + PP P CWVTGWG + E+ P P L++ +V +++ +C++ Sbjct: 120 GCLP-QFKAGPPRAPQTCWVTGWGYLK--EKGPRTSPTLQEARVALIDLELCNSTRW--- 173 Query: 197 YTGDDVRIVRDDMLCAGNTRR--DSCQGDSGGPLVCK--VNGTWLQAGVVSWGEGCAQPN 252 Y G +R +CAG R D+CQGDSGGPL+C+ T++ G+ SWG GCA+ Sbjct: 174 YNGR----IRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAK 229 Query: 253 RPGIYTRVTYYLDWIHHYV 271 RPG+YT YL+WI + Sbjct: 230 RPGVYTSTWPYLNWIASKI 248 >3NXP-A nrPDB Length = 424 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 93/267 (34%), Positives = 132/267 (49%), Gaps = 35/267 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 IV G +A PWQV L P + CG SLI +WVLTAAHC+ P K+ + Sbjct: 166 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 224 Query: 89 QLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H V Sbjct: 225 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 284 Query: 142 LP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKYHL 194 LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 285 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK----- 339 Query: 195 GAYTGDDVRI-VRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGE 246 D RI + D+M CAG R D+C+GDSGGP V K N W Q G+VSWGE Sbjct: 340 -----DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 394 Query: 247 GCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GC + + G YT V WI + + Sbjct: 395 GCDRDGKYGFYTHVFRLKKWIQKVIDQ 421 >5FCR-A nrPDB Length = 234 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 88/244 (36%), Positives = 130/244 (53%), Gaps = 23/244 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GGQEA P+ S++V+G H CGG+L+ QWVL+AAHC+ V D +++V L Sbjct: 1 ILGGQEAAAHARPYMASVQVNG---THVCGGTLLDEQWVLSAAHCM-DGVTDDDSVQVLL 56 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + + V ++ HP + D+ L +L + ++ HV + L + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK-YHLGAYTGDDVRIVR 206 PG C V GWG V + R P L Q++V IM C+ + YH G +V Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRPDV--LHQLRVSIMNRTTCNLRTYHDG--------VVT 166 Query: 207 DDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLD 265 +M+CA + RRD+C+GDSG PLVC G ++ GVV+WG C +PG+YTRV+ Y Sbjct: 167 INMMCAESNRRDTCRGDSGSPLVC---GDAVE-GVVTWGSRVCGNGKKPGVYTRVSSYRM 222 Query: 266 WIHH 269 WI + Sbjct: 223 WIEN 226 >1SC8-U nrPDB Length = 262 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 83/258 (32%), Positives = 125/258 (48%), Gaps = 20/258 (7%) Query: 28 RVGIVGGQEAPRSKWPWQVSL--RVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDL 83 R I+GG+ PW ++ R G + CGGSLI P WV++A HC P +D Sbjct: 13 RFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDY 72 Query: 84 AALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEP----VNVSSHV 137 + R + V +I+H + + DIALL++ S + Sbjct: 73 IVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTI 132 Query: 138 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 T++LP G C +TG+G ++ + L P LK V ++ + C ++ G+ Sbjct: 133 QTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPE-QLKMTVVKLISHRECQQPHYYGSE 191 Query: 198 TGDDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPG 255 V MLCA + + DSCQGDSGGPLVC + G G+VSWG GCA ++PG Sbjct: 192 -------VTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPG 244 Query: 256 IYTRVTYYLDWIHHYVPK 273 +YTRV+++L WI + + Sbjct: 245 VYTRVSHFLPWIRSHTKE 262 >4NZQ-A nrPDB Length = 557 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 93/267 (34%), Positives = 132/267 (49%), Gaps = 35/267 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 IV G +A PWQV L P + CG SLI +WVLTAAHC+ P K+ + Sbjct: 299 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 357 Query: 89 QLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H V Sbjct: 358 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 417 Query: 142 LP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKYHL 194 LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 418 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK----- 472 Query: 195 GAYTGDDVRI-VRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGE 246 D RI + D+M CAG R D+C+GDSGGP V K N W Q G+VSWGE Sbjct: 473 -----DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 527 Query: 247 GCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GC + + G YT V WI + + Sbjct: 528 GCDRDGKYGFYTHVFRLKKWIQKVIDQ 554 >3K65-B nrPDB Length = 308 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 92/267 (34%), Positives = 132/267 (49%), Gaps = 35/267 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 IV G +A PWQV L P + CG SLI +WVLTAAHC+ P K+ + Sbjct: 50 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 108 Query: 89 QLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H V Sbjct: 109 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 168 Query: 142 LP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKYHL 194 LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 169 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK----- 223 Query: 195 GAYTGDDVRI-VRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGE 246 D RI + D+M CAG R D+C+GD+GGP V K N W Q G+VSWGE Sbjct: 224 -----DSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGE 278 Query: 247 GCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GC + + G YT V WI + + Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVIDQ 305 >4XDE-A nrPDB Length = 257 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 93/254 (36%), Positives = 121/254 (47%), Gaps = 26/254 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVG--PDVKDLAALR 87 +VGG A R P+ +L YW H FC GSLI P WVLTAAHC+ P +DL + Sbjct: 3 VVGGLVALRGAHPYIAAL-----YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVN-----VSSHVHTVTL 142 Q R H Q L V +H F D+ALL L+E + +S +V V+L Sbjct: 58 GQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSL 117 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P + C V GWG F L++ +VP + C A G+ Sbjct: 118 PSGAARPSETTLCQVAGWGHQFEGAEEYASF-LQEAQVPFLSLERCSAPDVHGSS----- 171 Query: 203 RIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ---AGVVSWGEGCAQPNRPGIY 257 + MLCAG D+CQGDSGGPLVC+ + G++SWG GC N+PG+Y Sbjct: 172 --ILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVY 229 Query: 258 TRVTYYLDWIHHYV 271 T V YYL WI + Sbjct: 230 TDVAYYLAWIREHT 243 >1FDP-A nrPDB Length = 235 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 90/246 (36%), Positives = 125/246 (50%), Gaps = 26/246 (10%) Query: 28 RVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 R I+GG+EA P+ S++++G H CGG L+ QWVL+AAHC+ +D A + Sbjct: 5 RGRILGGREAEAHARPYMASVQLNG---AHLCGGVLVAEQWVLSAAHCL----EDAADGK 57 Query: 88 VQ-LREQHLYYQ----DQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142 VQ L H Q +L V R + HP I D+ LL+L E + V + Sbjct: 58 VQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPW 117 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK-YHLGAYTGDD 201 PG C V GWG V++ R P L+ V +P+++ C+ + +H GA T Sbjct: 118 QRVDRDVAPGTLCDVAGWGIVNHAGRRPDS--LQHVLLPVLDRATCNRRTHHDGAIT--- 172 Query: 202 VRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 + ++CA + RRDSC+GDSGGPLVC G L+ V S C +PGIYTRV Sbjct: 173 -----ERLMCAESNRRDSCKGDSGGPLVC---GGVLEGVVTSGSRVCGNRKKPGIYTRVA 224 Query: 262 YYLDWI 267 Y WI Sbjct: 225 SYAAWI 230 >1FON-A nrPDB Length = 240 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 123/249 (49%), Gaps = 18/249 (7%) Query: 34 GQEAPRSKWPWQVSLRVHGP-YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLRE 92 G++A W WQVSL+ + H CGGSLI P WV+TA HC+ + + + Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS-RTYQVVLGEYDR 60 Query: 93 QHLYYQDQLLPVS--RIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPPASET 148 L +Q++P++ + VHP + + + G DIAL++L + V LPPA + Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 P PC+++GWG + P P L+Q +P ++ C G V+ Sbjct: 121 LPNEAPCYISGWGRLYTGG--PLPDKLQQALLPTVDYEHCSQWDWWGI-------TVKKT 171 Query: 209 MLCAGNTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVTYYLD 265 M+CAG R C GDSGGPL C +G+W GV S+ GC +P ++TRV+ ++D Sbjct: 172 MVCAGGDTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFID 231 Query: 266 WIHHYVPKK 274 WI + Sbjct: 232 WIDETIASN 240 >1YM0-A nrPDB Length = 238 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 90/251 (35%), Positives = 129/251 (51%), Gaps = 20/251 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG EA ++PWQVS+R HFCGGS+I+ +WV+ AAHC+ + L +L V Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSD-SHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGE 59 Query: 91 REQHLYYQ-DQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP-PASET 148 + Q V I V+ + A + D+++++ + +V + P PA++ Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDY 119 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 C +GWG + N + P L+ V + I N CDA YT D + DD Sbjct: 120 VYRKSQC--SGWGTI-NSGGVCCPAVLRYVTLNITTNAFCDA-----VYTSD---TIYDD 168 Query: 209 MLCA----GNTRRDSCQGDSGGPLVCKV-NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 M+CA G T RDSCQGDSGGPL K +G + G+VSWG GCA PG+Y+RV ++ Sbjct: 169 MICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCAS-GYPGVYSRVGFH 227 Query: 264 LDWIHHYVPKK 274 WI + Sbjct: 228 AGWITDTITNN 238 >6BQM-A nrPDB Length = 506 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 86/245 (35%), Positives = 132/245 (53%), Gaps = 17/245 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG++A +WP+ V+L + FCGGS + ++VLTAAHCV D +D A V L Sbjct: 11 IIGGEQATAGEWPYMVALTARNSSHV-FCGGSYLGGRYVLTAAHCV--DKEDPAKGDVLL 67 Query: 91 R--EQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELE-EPVNVSSHVHTVTLPPASE 147 + + + + V +I VH + TA +G DIA+LELE +P+ S V + +S+ Sbjct: 68 GAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRS----VQISDSSD 123 Query: 148 --TFPPGMPCWVTGWGD---VDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P V G+G+ VD E+ P L QV+VP + C K ++ Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDG-EKSDPATILHQVQVPFVPLPECKTKGS-DQDAKNNY 181 Query: 203 RIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + ++ CAG+ +D+C GD+GGP+ N Q GVVSWG+GC + N PG+YT ++ Sbjct: 182 SQLTNNAFCAGSFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSV 241 Query: 263 YLDWI 267 + DW+ Sbjct: 242 FNDWL 246 >1YC0-A nrPDB Length = 283 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 86/279 (30%), Positives = 133/279 (47%), Gaps = 24/279 (8%) Query: 5 LLLALPVLAS---RAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGG 61 LL LP AS +A + R I+GG + PW ++ + FC G Sbjct: 7 LLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGD----SFCAG 62 Query: 62 SLIHPQWVLTAAHCVG--PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQ-I 118 SL+H WV++AAHC P ++ + Q Q + + I + + Sbjct: 63 SLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPS 122 Query: 119 GADIALLELEEP----VNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174 D+ L+ L++ S V + LP TFP G C + GWG +D + Sbjct: 123 DHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSS-S 181 Query: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKV 232 L++ VP++ +H C + GA + +MLCAG + + D+CQGDSGGPL C+ Sbjct: 182 LREALVPLVADHKCSSPEVYGA-------DISPNMLCAGYFDCKSDACQGDSGGPLACEK 234 Query: 233 NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271 NG G++SWG+GC + ++PG+YTRV Y+DWI+ + Sbjct: 235 NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 273 >1EUF-A nrPDB Length = 227 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 80/241 (33%), Positives = 119/241 (49%), Gaps = 24/241 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRVQ 89 I+GG EA P+ L H CGG L+ +VLTAAHC+G + L A + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 RE+ Q++PV R I HP + + DI LL+L +++ V + LP + Sbjct: 61 ERER----TQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PGM C V GWG + + +P L++V + + C A++ + Sbjct: 117 KPGMMCSVAGWGRLGVN--MPSTDKLQEVDLEVQSEEKCIARFK---------NYIPFTQ 165 Query: 210 LCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +CAG+ R++S GDSGGPLVC NG + G+VS+G P +YTR++ +L WI Sbjct: 166 ICAGDPSKRKNSFSGDSGGPLVC--NG--VAQGIVSYGRN--DGTTPDVYTRISSFLSWI 219 Query: 268 H 268 H Sbjct: 220 H 220 >2R0L-A nrPDB Length = 248 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 123/250 (49%), Gaps = 21/250 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAALRV 88 I+GG + PW ++ + FC GSL+H WV++AAHC P ++ + Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQ-IGADIALLELEEP----VNVSSHVHTVTLP 143 Q Q + + I + + D+ L+ L++ S V + LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 TFP G C + GWG +D + L++ VP++ +H C + GA Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSS-SLREALVPLVADHKCSSPEVYGA------- 168 Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 + +MLCAG + + D+CQGDSGGPL C+ NG G++SWG+GC + ++PG+YTRV Sbjct: 169 DISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVA 228 Query: 262 YYLDWIHHYV 271 Y+DWI+ + Sbjct: 229 NYVDWINDRI 238 >1VR1-H nrPDB Length = 261 Score = 127 bits (319), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 92/270 (34%), Positives = 130/270 (48%), Gaps = 37/270 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAA 85 IV G +A PWQV L P CG SLI +WVLTAAHC+ P K+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 86 LRVQLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVH 138 + +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 139 TVTLP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAK 191 V LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK-- 178 Query: 192 YHLGAYTGDDVRI-VRDDMLCA-----GNTRRDSCQGDSGGPLVCK--VNGTWLQAGVVS 243 D RI + D+M CA R D+C+GDSGGP V K N W Q G+VS Sbjct: 179 --------DSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 244 WGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 WGEGC + + G YT V WI + + Sbjct: 231 WGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 260 >2B9L-A nrPDB Length = 394 Score = 127 bits (318), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 78/255 (30%), Positives = 128/255 (50%), Gaps = 19/255 (7%) Query: 35 QEAPRSKWPWQVS-LRVH----GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 EA ++PW V+ L+ + CGGSLI P VLT AHCV +L A++++ Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 90 LREQHLYYQDQLLP-----VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144 E + + LP + ++I+H F + D+ALL L+ P+ + ++ T+ LP Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 S+ F C+ +GWG + R LK++++P ++ C A T ++ Sbjct: 255 QSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLR---NTRLGLKF 310 Query: 205 VRDD-MLCAGNTR-RDSCQGDSGGPLVC---KVNGTWLQAGVVSWGEGCAQPNRPGIYTR 259 V D +CAG + +D+C GD G PL C + ++Q G+V+WG GC N PG+Y Sbjct: 311 VLDQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYAN 370 Query: 260 VTYYLDWIHHYVPKK 274 V ++ +WI + K Sbjct: 371 VAHFRNWIDQEMQAK 385 >1MZD-A nrPDB Length = 240 Score = 126 bits (317), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/248 (33%), Positives = 124/248 (50%), Gaps = 31/248 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLA------ 84 I+GG+E P+ S++ G H CGG LI PQWVLTAAHC K + Sbjct: 3 IIGGKEVSPHSRPFMASIQYGG---HHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLG 59 Query: 85 --ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142 +L + + +P SR+ PQ DI L++L+ ++ HV + + Sbjct: 60 AHSLSKNEASKQTLEIKKFIPFSRVTSDPQ------SNDIMLVKLQTAAKLNKHVKMLHI 113 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 + + G C VTGWG D D L P L++V V ++ +C+++ + Y GD Sbjct: 114 -RSKTSLRSGTKCKVTGWGATDPDS-LRPSDTLREVTVTVLSRKLCNSQSY---YNGDP- 167 Query: 203 RIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260 + DM+CAG+ + +DSC+GD+GGPL+CK + +VS G C +PGIYT + Sbjct: 168 -FITKDMVCAGDAKGQKDSCKGDAGGPLICK----GVFHAIVSGGHECGVATKPGIYTLL 222 Query: 261 T-YYLDWI 267 T Y WI Sbjct: 223 TKKYQTWI 230 >1FXY-A nrPDB Length = 228 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 84/248 (33%), Positives = 127/248 (51%), Gaps = 31/248 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + PWQ L FCGG+++ ++LTAAHC+ +V++ Sbjct: 1 IVGGYNCKDGEVPWQALLINEEN--EGFCGGTILSEFYILTAAHCL----YQAKRFKVRV 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 +++ ++ + V +I H +F DIA+L L+ P+ +V +LP A Sbjct: 55 GDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA-- 112 Query: 148 TFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 PP G C ++GWG+ + P L+ + P++ C+A Y + Sbjct: 113 --PPATGTKCLISGWGNTASS-GADYPDELQCLDAPVLSQAKCEASYP---------GKI 160 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 +M C G +DSCQGDSGGP+VC NG LQ GVVSWG+GCAQ N+PG+YT+V Y Sbjct: 161 TSNMFCVGFLEGGKDSCQGDSGGPVVC--NGQ-LQ-GVVSWGDGCAQKNKPGVYTKVYNY 216 Query: 264 LDWIHHYV 271 + WI + + Sbjct: 217 VKWIKNTI 224 >5ZFH-A nrPDB Length = 224 Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 90/242 (37%), Positives = 120/242 (49%), Gaps = 31/242 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G + PWQV+L CGG L+ WVLTAAHC + +VQL Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQL---HCGGVLVDKYWVLTAAHC------KMGQYQVQL 51 Query: 91 REQHLYYQD-QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + Q Q + ++ HP + T DI L+ L+EPV +SS V V LP E Sbjct: 52 GSDKIGDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE-- 109 Query: 150 PPGMPCWVTGWGDVDN-DERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 PPG C V+GWG + D P VK ++ + C Y ++ Sbjct: 110 PPGTSCTVSGWGTTTSPDVTFPSDLMCSDVK--LISSRECKKVYK---------DLLGKT 158 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLD 265 MLCAG +++ ++C GDSGGPLVC N T LQ G+VSWG C QPN PG+YT+V Y Sbjct: 159 MLCAGIPDSKTNTCNGDSGGPLVC--NDT-LQ-GLVSWGTYPCGQPNDPGVYTQVCKYKR 214 Query: 266 WI 267 W+ Sbjct: 215 WV 216 >1FI8-A nrPDB Length = 228 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 82/247 (33%), Positives = 130/247 (52%), Gaps = 24/247 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPY-WMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRV 88 I+GG EA P+ L++ Y CGG LI +VLTAAHC G ++ L A + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + +E+ Q++PV +II HP + + I DI LL+L+ SS V + LP + Sbjct: 61 KEQEK----MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 PG C+V GWG + + L++V++ + E+ C++ +L Y + + Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSD--TLQEVELTVQEDQKCES--YLKNY------FDKAN 166 Query: 209 MLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 +CAG+ +R S +GDSGGPLVCK + AG+VS+G+ + P +T+V+ +L W Sbjct: 167 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQN--DGSTPRAFTKVSTFLSW 220 Query: 267 IHHYVPK 273 I + K Sbjct: 221 IKKTMKK 227 >1SI5-H nrPDB Length = 240 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 87/241 (36%), Positives = 122/241 (50%), Gaps = 30/241 (12%) Query: 39 RSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYY 97 R+ W VSLR H CGGSLI WVLTA C D+KD A + + + H Sbjct: 8 RTNIGWMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAW-LGIHDVHGRG 63 Query: 98 QD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMP 154 + Q+L VS+++ P+ G+D+ L++L P + V T+ LP T P Sbjct: 64 DEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTS 117 Query: 155 CWVTGWG--DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA 212 C V GWG + N + L L+ + IM N C +++H G T + + +CA Sbjct: 118 CSVYGWGYTGLINYDGL-----LRVAHLYIMGNEKC-SQHHRGKVT------LNESEICA 165 Query: 213 GNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 G + S C+GD GGPLVC+ + + GV+ G GCA PNRPGI+ RV YY WIH Sbjct: 166 GAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKI 225 Query: 271 V 271 + Sbjct: 226 I 226 >1A5I-A nrPDB Length = 265 Score = 124 bits (311), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 89/263 (33%), Positives = 126/263 (47%), Gaps = 45/263 (17%) Query: 32 VGGQEAPRSKWPWQVSL-----RVHGPYWMHFCGGSLIHPQWVLTAAHCVG----PDVKD 82 GG + PWQ ++ R G ++ CGG LI WVLTAAHC PD Sbjct: 15 TGGLFTDITSHPWQAAIFAQNRRSSGERFL--CGGILISSCWVLTAAHCFQESYLPD--- 69 Query: 83 LAALRVQLREQHLYY---QDQLLPVSRIIVHPQFYTAQIGADIALLELE----EPVNVSS 135 L+V L + ++Q V + IVH +F DIALL+L+ + S Sbjct: 70 --QLKVVLGRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESD 127 Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK---VPIMENHICDAKY 192 V + LP A+ P C ++G+G + PF +Q+K V + + C K+ Sbjct: 128 SVRAICLPEANLQLPDWTECELSGYGK----HKSSSPFYSEQLKEGHVRLYPSSRCAPKF 183 Query: 193 HLGAYTGDDVRIVRDDMLCAGNTRR--------DSCQGDSGGPLVCKVNGTWLQAGVVSW 244 + V ++MLCAG+TR D+CQGDSGGPLVC + G++SW Sbjct: 184 LFN-------KTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISW 236 Query: 245 GEGCAQPNRPGIYTRVTYYLDWI 267 G GC + + PG+YT+VT YL WI Sbjct: 237 GVGCGEKDVPGVYTKVTNYLGWI 259 >1C5M-D nrPDB Length = 255 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 79/252 (31%), Positives = 121/252 (48%), Gaps = 25/252 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQE + PWQ L FCGG+++ ++LTAAHC+ +V++ Sbjct: 1 IVGGQECKDGECPWQALL--INEENEGFCGGTILSEFYILTAAHCL----YQAKRFKVRV 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP--- 144 +++ ++ + V +I H +F DIA+L L+ P+ +V LP Sbjct: 55 GDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDW 114 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A T V+G+G R LK ++VP ++ + C I Sbjct: 115 AESTLMTQKTGIVSGFGRTHEKGRQSTR--LKMLEVPYVDRNSCKLSSSF---------I 163 Query: 205 VRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + +M CAG + D+CQGDSGGP V + T+ G+VSWGEGCA+ + GIYT+VT Sbjct: 164 ITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTA 223 Query: 263 YLDWIHHYVPKK 274 +L WI + + Sbjct: 224 FLKWIDRSMKTR 235 >3QUM-P nrPDB Length = 237 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 91/261 (34%), Positives = 125/261 (47%), Gaps = 40/261 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQV + G CGG L+HPQWVLTAAHC+ L Sbjct: 1 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRNKSVILLG----- 52 Query: 91 REQHLYYQD--QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSHV 137 R + +D Q+ VS HP + + + D+ LL L EP ++ V Sbjct: 53 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 112 Query: 138 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 + LP G C+ +GWG ++ +E L P L+ V + ++ N +C A+ H Sbjct: 113 KVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPK-KLQCVDLHVISNDVC-AQVH---- 164 Query: 198 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRP 254 + V MLCAG + +C GDSGGPLVC NG + G+ SWG E CA P RP Sbjct: 165 ----PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSWGSEPCALPERP 216 Query: 255 GIYTRVTYYLDWIHHYVPKKP 275 +YT+V +Y WI + P Sbjct: 217 SLYTKVVHYRKWIKDTIVANP 237 >5TO3-B nrPDB Length = 409 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 91/267 (34%), Positives = 130/267 (48%), Gaps = 35/267 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88 IV G +A PWQV L P + CG SLI +WVLTAAHC+ P K+ + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 89 QLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKYHL 194 LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK----- 174 Query: 195 GAYTGDDVRI-VRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGE 246 D RI + D+M CAG R D+C+GDSGGP V K N W Q G+VS G Sbjct: 175 -----DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA 229 Query: 247 GCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GC + + G YT V WI + + Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVIDQ 256 >5MS3-A nrPDB Length = 228 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 90/252 (35%), Positives = 127/252 (50%), Gaps = 33/252 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E PWQ +L G + CGG L+ WVLTAAHC P V+L Sbjct: 1 VLGGHECQPHSQPWQAAL-FQGQQLL--CGGVLVGGNWVLTAAHCKKP------KYTVRL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI---GADIALLELEEPVNVSSHVHTVTLPP 144 + L +D Q +PV + I HP + ++ + D+ LL+L + ++ S V ++L Sbjct: 52 GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL-- 109 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A PG C V+GWG V R P L +V I C+ AY G Sbjct: 110 ADHCTQPGQKCTVSGWGTV-TSPRENFPDTLNCAEVKIFPQKKCED-----AYPGQ---- 159 Query: 205 VRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTY 262 + D M+CAG+++ D+CQGDSGGPLVC LQ G+ SWG C + ++PG+YT + Sbjct: 160 ITDGMVCAGSSKGADTCQGDSGGPLVCD---GALQ-GITSWGSDPCGRSDKPGVYTNICR 215 Query: 263 YLDWIHHYVPKK 274 YLDWI + K Sbjct: 216 YLDWIKKIIGSK 227 >5KWM-A nrPDB Length = 230 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 122/245 (49%), Gaps = 27/245 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQ 89 IVGG++A P+ V+L P FCGG+L P V+TAAHC VG D+ V Sbjct: 1 IVGGEDANVQDHPFTVALVT--PDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINV--VS 56 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET- 148 R + + V+ + VHP++ A G D+++L LE PV + + L A + Sbjct: 57 GRTVMSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAP----IELAKADDAG 112 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 + P + GWG+ E L++ VP+ + C Y G YT D Sbjct: 113 YAPDTAATILGWGNTS--EGGQQADHLQKATVPVNSDDTCKQAY--GEYT-------PDA 161 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 M+CAG D+CQGDSGGP+V VN + GV SWGEGCA+P +PG+Y RV Y D Sbjct: 162 MVCAGVPEGGVDTCQGDSGGPMV--VNNKLI--GVTSWGEGCARPGKPGVYARVGAYYDV 217 Query: 267 IHHYV 271 + + Sbjct: 218 LMEQI 222 >1PQ7-A nrPDB Length = 224 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 83/245 (33%), Positives = 113/245 (46%), Gaps = 25/245 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG A +P+ VS+ +G W CGGSL++ VLTAAHCV A Q+ Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPW---CGGSLLNANTVLTAAHCV----SGYAQSGFQI 53 Query: 91 REQHLYYQDQLL--PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 R L + +S + VHP + D+A+L+L + ++ L + Sbjct: 54 RAGSLSRTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G V GWG ++ P L +V VPI+ C A+Y A T + Sbjct: 112 PVAGSSATVAGWG-ATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAIT--------NQ 162 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 M CAG + +DSCQGDSGGP+V N G VSWG GCA+PN G+Y V + Sbjct: 163 MFCAGVSSGGKDSCQGDSGGPIVDSSN---TLIGAVSWGNGCARPNYSGVYASVGALRSF 219 Query: 267 IHHYV 271 I Y Sbjct: 220 IDTYA 224 >3BSQ-A nrPDB Length = 227 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 87/242 (35%), Positives = 122/242 (50%), Gaps = 29/242 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G R PWQV+L CGG L++ +WVLTAAHC + V L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHC------KMNEYTVHL 51 Query: 91 REQHL-YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 L + Q + S+ HP + T D+ L++L +SS V V LP E Sbjct: 52 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 109 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PPG C V+GWG + + + P L V V ++ C Y ++ + M Sbjct: 110 PPGTTCTVSGWGTTTSPD-VTFPSDLMCVDVKLISPQDCTKVYK---------DLLENSM 159 Query: 210 LCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDW 266 LCAG ++++++C GDSGGPLVC+ GT LQ G+VSWG C QPN PG+YT+V + W Sbjct: 160 LCAGIPDSKKNACNGDSGGPLVCR--GT-LQ-GLVSWGTFPCGQPNDPGVYTQVCKFTKW 215 Query: 267 IH 268 I+ Sbjct: 216 IN 217 >1SGF-G nrPDB Length = 237 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 86/266 (32%), Positives = 127/266 (47%), Gaps = 50/266 (18%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + ++ PW V++ Y + CGG L+ P WVLTAAHC + K V L Sbjct: 1 IVGGFKCEKNSQPWHVAVYR---YTQYLCGGVLLDPNWVLTAAHCYDDNYK------VWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSH 136 + +L+ + Q VS+ I HP F + + D+ LL L +P +++ Sbjct: 52 GKNNLFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDT 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQ----VKVPIMENHICDAKY 192 V +TLP +E G C +GWG + P F V + ++ N C AK Sbjct: 112 VKPITLP--TEEPKLGSTCLASGWGSI-----TPTKFQFTDDLYCVNLKLLPNEDC-AKA 163 Query: 193 HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CA 249 H + V D MLCAG +D+C+GDSGGPL+C + G+ SWG C Sbjct: 164 H--------IEKVTDAMLCAGEMDGGKDTCKGDSGGPLICD----GVLQGITSWGHTPCG 211 Query: 250 QPNRPGIYTRVTYYLDWIHHYVPKKP 275 +P+ PG+YT++ + WI + K P Sbjct: 212 EPDMPGVYTKLNKFTSWIKDTMAKNP 237 >2XRC-A nrPDB Length = 565 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 87/264 (32%), Positives = 125/264 (47%), Gaps = 39/264 (14%) Query: 26 LQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAA 85 ++R IVGG+ A PWQV+++ CGG I W+LTAAHC L A Sbjct: 317 IRRKRIVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHC-------LRA 366 Query: 86 LRVQLREQHLYYQDQLLP---------VSRIIVHPQFYTAQIGADIALLELEEPVNVSSH 136 + + D + P V RII H + DIAL+E+++ N Sbjct: 367 SKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDC 426 Query: 137 VHTVTLPP----ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192 ++P + F P C V+GWG ++ER+ F L+ +V ++ N Sbjct: 427 ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN------- 476 Query: 193 HLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCA 249 + G+ R +M CAG + D+C+GDSGGPLVC N GVVSWGE C Sbjct: 477 -CSKFYGN--RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG 533 Query: 250 QPNRPGIYTRVTYYLDWIHHYVPK 273 +P PG+YT+V Y DWI ++V + Sbjct: 534 KPEFPGVYTKVANYFDWISYHVGR 557 >1KIG-H nrPDB Length = 241 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 120/250 (48%), Gaps = 21/250 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++ + PWQ L FCGG++++ +VLTAAHC+ + +RV Sbjct: 1 IVGGRDCAEGECPWQALLV--NEENEGFCGGTILNEFYVLTAAHCLHQAKR--FTVRVGD 56 Query: 91 REQHLYYQDQLL-PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP---AS 146 R +++ V + H +F DIA+L L+ P+ +V LP A Sbjct: 57 RNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAE 116 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 T V+G+G RL LK ++VP ++ C + Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSST--LKMLEVPYVDRSTCKLSSSF---------TIT 165 Query: 207 DDMLCAG-NTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 +M CAG +T+ D+CQGDSGGP V + T+ G+VSWGEGCA+ + G+YT+V+ +L Sbjct: 166 PNMFCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFL 225 Query: 265 DWIHHYVPKK 274 WI + + Sbjct: 226 KWIDKIMKAR 235 >1GPZ-A nrPDB Length = 399 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 84/260 (32%), Positives = 138/260 (53%), Gaps = 27/260 (10%) Query: 27 QRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP---DVKDL 83 QR I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH + P + + Sbjct: 154 QRQQIIGGQKAKMGNFPWQVFTNIHGR-----GGGALLGDRWILTAAHTLYPKEHEAQSN 208 Query: 84 AALRVQLREQHLYYQDQL--LPVSRIIVHPQFY---TAQIGADIALLELEEPVNVSSHVH 138 A+L V L ++ +L P+ R+ VHP + + DIALLELE V + ++ Sbjct: 209 ASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLL 268 Query: 139 TVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYT 198 + LP + G+ +V+G+G + +E++ L+ V++P+ C+ + G Sbjct: 269 PICLPDNDTFYDLGLMGYVSGFGVM--EEKI--AHDLRFVRLPVANPQACE-NWLRGKNR 323 Query: 199 GDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGEGCAQPNRP 254 D + +M CAG + ++D+CQGDSGG + T W+ G+VSWG GC++ Sbjct: 324 MD---VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGY-- 378 Query: 255 GIYTRVTYYLDWIHHYVPKK 274 G YT+V Y+DWI + ++ Sbjct: 379 GFYTKVLNYVDWIKKEMEEE 398 >5O32-I nrPDB Length = 244 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 87/259 (33%), Positives = 121/259 (46%), Gaps = 39/259 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ A PWQV+++ CGG I W+LTAAHC L A + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHC-------LRASKTHR 50 Query: 91 REQHLYYQDQLLP---------VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVT 141 + D + P V RII H + DIAL+E+++ N + Sbjct: 51 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRS 110 Query: 142 LPP----ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 +P + F P C V+GWG ++ER+ F L+ +V ++ N C Y Sbjct: 111 IPACVPWSPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN--CSKFY----- 160 Query: 198 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP 254 R +M CAG + D+C+GDSGGPLVC N GVVSWGE C +P P Sbjct: 161 ---GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFP 217 Query: 255 GIYTRVTYYLDWIHHYVPK 273 G+YT+V Y DWI ++V + Sbjct: 218 GVYTKVANYFDWISYHVGR 236 >2QY0-B nrPDB Length = 242 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 136/256 (53%), Gaps = 27/256 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP---DVKDLAALR 87 I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH + P + + A+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR-----GGGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 88 VQLREQHLYYQDQL--LPVSRIIVHPQFY---TAQIGADIALLELEEPVNVSSHVHTVTL 142 V L ++ +L P+ R+ VHP + + DIALLELE V + ++ + L Sbjct: 56 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 115 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P + G+ +V+G+G + +E++ L+ V++P+ C+ + G D Sbjct: 116 PDNDTFYDLGLMGYVSGFGVM--EEKI--AHDLRFVRLPVANPQACE-NWLRGKNRMD-- 168 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGEGCAQPNRPGIYT 258 + +M CAG + ++D+CQGDSGG + T W+ G+VSWG GC++ G YT Sbjct: 169 -VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRG--YGFYT 225 Query: 259 RVTYYLDWIHHYVPKK 274 +V Y+DWI + ++ Sbjct: 226 KVLNYVDWIKKEMEEE 241 >1MD7-A nrPDB Length = 328 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 83/253 (32%), Positives = 135/253 (53%), Gaps = 27/253 (10%) Query: 27 QRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP---DVKDL 83 QR I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH + P + + Sbjct: 86 QRQRIIGGQKAKMGNFPWQVFTNIHGR-----GGGALLGDRWILTAAHTLYPKEHEAQSN 140 Query: 84 AALRVQLREQHLYYQDQL--LPVSRIIVHPQFY---TAQIGADIALLELEEPVNVSSHVH 138 A+L V L ++ +L P+ R+ VHP + + DIALLELE V + ++ Sbjct: 141 ASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLL 200 Query: 139 TVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYT 198 + LP + G+ +V+G+G + +E++ L+ V++P+ C+ + G Sbjct: 201 PICLPDNDTFYDLGLMGYVSGFGVM--EEKI--AHDLRFVRLPVANPQACE-NWLRGKNR 255 Query: 199 GDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGEGCAQPNRP 254 D + +M CAG + ++D+CQGD+GG + T W+ G+VSWG GC++ Sbjct: 256 MD---VFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGY-- 310 Query: 255 GIYTRVTYYLDWI 267 G YT+V Y+DWI Sbjct: 311 GFYTKVLNYVDWI 323 >3G01-A nrPDB Length = 227 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 127/243 (52%), Gaps = 28/243 (11%) Query: 31 IVGGQE-APRSK--WPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAAL 86 I+GG E +P S+ + L+V G FCGG L+ ++VLTAAHC G + L A Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKM--FCGGFLVRDKFVLTAAHCKGRSMTVTLGAH 58 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 ++ +E+ Q++PV++ I HP + DI LL+L + V + LP + Sbjct: 59 NIKAKEE----TQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRN 114 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 PG C+V GWG V D P L +VK+ + ++ +C++++ +Y R Sbjct: 115 AHVKPGDECYVAGWGKVTPDGEFPK--TLHEVKLTVQKDQVCESQFQ-SSYN-------R 164 Query: 207 DDMLCAGNTRRD--SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 + +C G+++ S +GDSGGPLVCK AG+VS+G+ + P ++TRV ++ Sbjct: 165 ANEICVGDSKIKGASFRGDSGGPLVCK----RAAAGIVSYGQ--TDGSAPQVFTRVLSFV 218 Query: 265 DWI 267 WI Sbjct: 219 SWI 221 >4LK4-A nrPDB Length = 357 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 83/252 (32%), Positives = 126/252 (50%), Gaps = 24/252 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGP--YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88 I+ G A ++WP V+L G Y FCGGS + ++VLTAAHC D + A++ V Sbjct: 11 IINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCF--DSRSAASVDV 68 Query: 89 QLREQHL--YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP-PA 145 + L Q + + +I H + + + DIA++EL + +S + +TL PA Sbjct: 69 IIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPAITLAGPA 124 Query: 146 SETFPPGM-PCWVTGWGDVDNDERLPPPFP--LKQVKVPIMENHICDAKYHLGAYTGDDV 202 + T P + P V GWG + PP F L++V V ++ +C G + + Sbjct: 125 TRTSLPALTPLTVAGWGITVQSK--PPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPN- 181 Query: 203 RIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVT 261 CA +DSCQGD+GGP+V K Q G+VSWG E CA+ G+YT V+ Sbjct: 182 ----STNFCAARLTKDSCQGDAGGPIVVKTGRE--QLGIVSWGDEQCAKTGTYGVYTNVS 235 Query: 262 YYLDWIHHYVPK 273 Y+ DWI + + Sbjct: 236 YFRDWITKHTNQ 247 >1EQ9-A nrPDB Length = 222 Score = 116 bits (291), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 125/246 (50%), Gaps = 27/246 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++AP K+P+QVSLR+ G H CG S++ VLTAAHCV + +L L+V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGS---HRCGASILDNNNVLTAAHCV-DGLSNLNRLKVHV 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 +L + V +V+ + + D+AL+ L P+ + V + L E Sbjct: 57 GTNYLSESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 151 PGMPCWVTGWGDVDNDERL--PPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 PC +TGWG RL P L+++++ + C+ D R++ D Sbjct: 117 SN-PCTLTGWGST----RLGGNTPNALQEIELIVHPQKQCER---------DQWRVI-DS 161 Query: 209 MLCAGNTRRD-SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +C R + +C GDSGGPLV NG Q G+VS+G CA P +YTRV+ ++ WI Sbjct: 162 HICTLTKRGEGACHGDSGGPLV--ANGA--QIGIVSFGSPCAL-GEPDVYTRVSSFVSWI 216 Query: 268 HHYVPK 273 + + K Sbjct: 217 NANLKK 222 >2PSX-A nrPDB Length = 227 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 125/247 (50%), Gaps = 30/247 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G + PWQ +L + P + +CG L+HPQW+LTAAHC RV+L Sbjct: 1 IINGSDCDMHTQPWQAALLLR-PNQL-YCGAVLVHPQWLLTAAHC------RKKVFRVRL 52 Query: 91 REQHL--YYQD--QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L Y+ Q+ + I HP + D+ L++L + + V + + +S Sbjct: 53 GHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV--SS 110 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 G C V+GWG + + + P L+ + + ++ C+ Y R + Sbjct: 111 HCPSAGTKCLVSGWGTTKSPQ-VHFPKVLQCLNISVLSQKRCEDAY---------PRQID 160 Query: 207 DDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 264 D M CAG+ RDSCQGDSGGP+VC NG+ LQ G+VSWG+ CA+PNRPG+YT + + Sbjct: 161 DTMFCAGDKAGRDSCQGDSGGPVVC--NGS-LQ-GLVSWGDYPCARPNRPGVYTNLCKFT 216 Query: 265 DWIHHYV 271 WI + Sbjct: 217 KWIQETI 223 >3RP2-A nrPDB Length = 224 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 83/243 (34%), Positives = 124/243 (51%), Gaps = 28/243 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVGPDVK-DLAALRV 88 I+GG E+ P+ L + + CGG LI Q+VLTAAHC G ++ L A V Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + RE Q + V + I+H + + DI LL+LE+ V ++ V+ V LP S+ Sbjct: 61 RKRES----TQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAKYHLGAYTGDDVRIVRD 207 PG CW GWG R P + L++V++ IM+ C D +Y+ + Sbjct: 117 IHPGAMCWAAGWG--KTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKF---------- 164 Query: 208 DMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +C G+ T R + GDSGGPL+C + G+VS+G A+P P I+TRV+ Y+ Sbjct: 165 -QVCVGSPTTLRAAFMGDSGGPLLC----AGVAHGIVSYGHPDAKP--PAIFTRVSTYVP 217 Query: 266 WIH 268 WI+ Sbjct: 218 WIN 220 >2ASU-B nrPDB Length = 234 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 111/239 (46%), Gaps = 33/239 (13%) Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL-----REQHLYY 97 PW VSLR HFCGGSL+ QW+LTA C L V L QH Sbjct: 10 PWTVSLR--NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEP 67 Query: 98 QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157 Q +PV++++ P G+ + LL+LE V ++ V + LPP PPG C + Sbjct: 68 SLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPEWYVVPPGTKCEI 121 Query: 158 TGWGDVD---NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN 214 GWG+ ND L + ++ N C+ K H G VR+ +C Sbjct: 122 AGWGETKGTGNDTVLNVAL------LNVISNQECNIK-HRGR--------VRESEMCTEG 166 Query: 215 TRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271 +C+GD GGPL C + +W+ G++ CA+ P ++TRV+ ++DWIH + Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 225 >6QHB-A nrPDB Length = 223 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 120/250 (48%), Gaps = 33/250 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +V G ++ P+Q +L G CGG LIHP WVLTAAHC P+ L+V L Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHL---LCGGVLIHPLWVLTAAHCKKPN------LQVFL 51 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 + +L + V R ++HP + A DI LL L P +S + LP + Sbjct: 52 GKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ--PLPLERD 109 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 C + GWG + + P ++ + ++ C+ AY G + Sbjct: 110 CSAQTTSCHILGWGKTADGDF---PDTIQCAYIHLVSREECEH-----AYPGQ----ITQ 157 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 264 +MLCAG+ + +DSCQGDSGGPLVC G L+ G+VSWG C +PG+YT V Y Sbjct: 158 NMLCAGDEKYGKDSCQGDSGGPLVC---GDHLR-GLVSWGNIPCGSKEKPGVYTNVCRYT 213 Query: 265 DWIHHYVPKK 274 +WI + K Sbjct: 214 NWIQKTIQAK 223 >1SPJ-A nrPDB Length = 238 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 85/262 (32%), Positives = 122/262 (46%), Gaps = 43/262 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQ +L + CGG L+H QWVLTAAHC+ + ++ L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ---CGGILVHRQWVLTAAHCISDN------YQLWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVN-VSS 135 +L+ + Q + VS HP F + + D+ LL L EP + ++ Sbjct: 52 GRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITD 111 Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195 V V LP +E G C +GWG ++ E P L+ V + I+ N C + Sbjct: 112 AVKVVELP--TEEPEVGSTCLASGWGSIE-PENFSFPDDLQCVDLKILPNDECKKAH--- 165 Query: 196 AYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPN 252 V+ V D MLC G+ +D+C GDSGGPL+C + GV SWG C PN Sbjct: 166 ------VQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCD----GVLQGVTSWGYVPCGTPN 215 Query: 253 RPGIYTRVTYYLDWIHHYVPKK 274 +P + RV Y+ WI + + Sbjct: 216 KPSVAVRVLSYVKWIEDTIAEN 237 >1NN6-A nrPDB Length = 228 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 120/246 (48%), Gaps = 28/246 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRV---HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 I+GG E P+ L + +GP FCGG LI +VLTAAHC G + Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGP--SKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E+ + Q L V + HP++ T+ + DI LL+L+E +++ V T+ P Sbjct: 61 NITEEEDTW---QKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 117 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PPG C V GWG + P L++VK+ +M+ C H + + Sbjct: 118 FVPPGRMCRVAGWGRTGVLK--PGSDTLQEVKLRLMDPQACS---HFRDFD-------HN 165 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 LC GN R + + +GDSGGPL+C + G+VS+G A+P P ++TR+++Y Sbjct: 166 LQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYRP 219 Query: 266 WIHHYV 271 WI+ + Sbjct: 220 WINQIL 225 >1KYN-A nrPDB Length = 235 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 120/241 (49%), Gaps = 25/241 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRVQ 89 I+GG+E+ P+ L++ P CGG L+ +VLTAAHC G ++ L A +Q Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 RE Q + R I HPQ+ I DI LL+L V + +V+ V LP A E Sbjct: 61 RREN----TQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PG C V GWG V L++V++ + + C + G+Y D R Sbjct: 117 RPGTLCTVAGWGRVSMRR---GTDTLREVQLRVQRDRQCLRIF--GSY---DPR----RQ 164 Query: 210 LCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +C G+ R+ + +GDSGGPL+C + G+VS+G+ P P ++TRV+ +L WI Sbjct: 165 ICVGDRRERKAAFKGDSGGPLLCNN----VAHGIVSYGKSSGVP--PEVFTRVSSFLPWI 218 Query: 268 H 268 Sbjct: 219 R 219 >3TK9-A nrPDB Length = 226 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 74/246 (30%), Positives = 118/246 (47%), Gaps = 24/246 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRVQ 89 I+GG EA P+ ++ CGG L+ +VLTAAHC G + L A ++ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 +E+ Q +PV R I HP + +I LL+LE ++ V + LP + Sbjct: 61 EQER----TQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PG C V GWG V L++V + + ++ C+ +H G Y+ R Sbjct: 117 KPGQLCSVAGWGYVSMSTLAT---TLQEVLLTVQKDCQCERLFH-GNYS-------RATE 165 Query: 210 LCAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +C G+ ++ +GDSGGPLVCK + G++S+G P PG+Y +V+++L WI Sbjct: 166 ICVGDPKKTQTGFKGDSGGPLVCKD----VAQGILSYGNKKGTP--PGVYIKVSHFLPWI 219 Query: 268 HHYVPK 273 + + Sbjct: 220 KRTMKR 225 >4GSO-A nrPDB Length = 232 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/248 (31%), Positives = 127/248 (51%), Gaps = 33/248 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ P+ L HG +FCG +LI+ +WV+TAAHC + + +++ + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG----YFCGLTLINQEWVVTAAHCDSTNFQ----MQLGV 52 Query: 91 REQHLYYQDQLL--PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ P + I + + + DI L++L++P++ S H+ ++LP + Sbjct: 53 HSKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLP----S 108 Query: 149 FPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 PP G C + GWG + P P + +++ +C GAY G + Sbjct: 109 NPPSVGSVCRIMGWGSITIPNETYPDVPY-CANINLVDYEVCQ-----GAYNGLPAKTT- 161 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYY 263 LCAG +D+C GDSGGPL+C NG + G+VS+G C Q +PGIYT V Y Sbjct: 162 ---LCAGVLEGGKDTCVGDSGGPLIC--NGQF--QGIVSYGAHSCGQGPKPGIYTNVFDY 214 Query: 264 LDWIHHYV 271 DWI + Sbjct: 215 TDWIQRNI 222 >2BDH-A nrPDB Length = 223 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 122/244 (50%), Gaps = 26/244 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G++ PWQ +L + FC G L+HPQWVL+AAHC L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYT--IGLGLHS 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 E Q++ S + HP++ + D+ L++L+E V+ S + ++++ AS+ Sbjct: 56 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPT 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C V+GWG + N P L+ V V ++ +C Y + M Sbjct: 114 AGNSCLVSGWGLLANGRM---PTVLQCVNVSVVSEEVCSKLYD---------PLYHPSMF 161 Query: 211 CA--GNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDWI 267 CA G ++DSC GDSGGPL+C NG +LQ G+VS+G+ C Q PG+YT + + +WI Sbjct: 162 CAGGGQDQKDSCNGDSGGPLIC--NG-YLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWI 217 Query: 268 HHYV 271 V Sbjct: 218 EKTV 221 >1FUJ-A nrPDB Length = 221 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/242 (33%), Positives = 118/242 (48%), Gaps = 31/242 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG EA P+ SL++ G HFCGG+LIHP +VLTAAHC+ + L + V L Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 58 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q+ Q V+++ ++ ++ DI L++L P N+S+ V TV LP + Sbjct: 59 GAHNVRTQEPTQQHFSVAQVFLNNYDAENKLN-DILLIQLSSPANLSASVATVQLPQQDQ 117 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P G C GWG V + PP L+++ V ++ R Sbjct: 118 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVV------------------TFFCRP 157 Query: 208 DMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +C RR + C GDSGGPL+C + + V+ W GCA P +TRV Y+D Sbjct: 158 HNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVI-W--GCATRLFPDFFTRVALYVD 214 Query: 266 WI 267 WI Sbjct: 215 WI 216 >4IW4-E nrPDB Length = 279 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 87/270 (32%), Positives = 129/270 (47%), Gaps = 41/270 (15%) Query: 31 IVGGQEAPRSKWPWQVSL------RVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLA 84 I+GG+ A +PWQ + RV W F G+L+ W+LTAAH + +D Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKW--FGSGALLSASWILTAAHVLRSQRRDTT 58 Query: 85 ALRVQLREQHLYY-----QDQLLPV----SRIIVHPQFYTAQIGADIALLELEEPVNVSS 135 + V +Y +D+ V +R+++HP F DIAL++L+EPV + Sbjct: 59 VIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 118 Query: 136 HVHTVTLPPASETFP-PGMPCWVTGWG----DVDNDERLPPPFP-----LKQVKVPIMEN 185 HV V LP P P M V GWG +V DE + L+ VK+P++ + Sbjct: 119 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 178 Query: 186 HICDAKYH--LGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC--KVNGTWLQA 239 C Y G Y+ V ++M CAG +D+C GDSGG V ++ W+ Sbjct: 179 AECKTSYESRSGNYS------VTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQ 232 Query: 240 GVVSWG--EGCAQPNRPGIYTRVTYYLDWI 267 G+VSWG E C G+YT+V+ Y+DW+ Sbjct: 233 GLVSWGGPEECGSKQVYGVYTKVSNYVDWV 262 >1TON-A nrPDB Length = 235 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 115/259 (44%), Gaps = 38/259 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + ++ PWQV++ + CGG LI P WV+TAAHC + + L R L Sbjct: 1 IVGGYKCEKNSQPWQVAVINE-----YLCGGVLIDPSWVITAAHCYSNNYQVLLG-RNNL 54 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSHVHT 139 + + Q +L V + HP + + D+ LL L EP +++ V Sbjct: 55 FKDEPFAQRRL--VRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKV 112 Query: 140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 199 + LP G C +GWG N + L+ V + ++ N C Y Sbjct: 113 IDLPTKEPKV--GSTCLASGWGST-NPSEMVVSHDLQCVNIHLLSNEKCIETYKDN---- 165 Query: 200 DDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGI 256 V D MLCAG +D+C GDSGGPL+C + G+ S G CA+P P I Sbjct: 166 -----VTDVMLCAGEMEGGKDTCAGDSGGPLICD----GVLQGITSGGATPCAKPKTPAI 216 Query: 257 YTRVTYYLDWIHHYVPKKP 275 Y ++ + WI + + P Sbjct: 217 YAKLIKFTSWIKKVMKENP 235 >3I77-A nrPDB Length = 230 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 22/241 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V R+ FCGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMV--RLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P F G D AL++L +P+N + T TF Sbjct: 59 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTFT 118 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + +V ++M+ Sbjct: 119 ------VAGWGA--NREGGSQQRYLLKANVPFVSDAACRSSSSF--------ILVANEMI 162 Query: 211 CAG---NTRRDSCQGDSGGPLVCKVNG-TWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 CAG D+CQGDSGGP+ K N W+Q G+VSWG GCA+P PG+YT V+ + Sbjct: 163 CAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASA 222 Query: 267 I 267 I Sbjct: 223 I 223 >4BXW-A nrPDB Length = 423 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 78/260 (30%), Positives = 128/260 (49%), Gaps = 29/260 (11%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88 + IV G + + PWQ +L FCGG+++ P +VLTAAHC+ + + ++ + Sbjct: 168 IRIVNGMDCKLGECPWQAALVDEKEGV--FCGGTILSPIYVLTAAHCIN-ETETISVVVG 224 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQF------YTAQIGA---DIALLELEEPVNVSSHVHT 139 ++ + + LL V +I VH +F Y + A DIA+++++ P+ S +V Sbjct: 225 EIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVP 283 Query: 140 VTLPPA---SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 LP A ++ V+G+G + E+ P LK +KVP ++ H C Sbjct: 284 ACLPTADFANQVLMKQDFGIVSGFGRIV--EKGPKSKTLKVLKVPYVDRHTCMVSSETP- 340 Query: 197 YTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRP 254 + +M CAG RD+CQGDSGGP T G+VS GEGCA+ + Sbjct: 341 --------ITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKY 392 Query: 255 GIYTRVTYYLDWIHHYVPKK 274 G YT+++ ++ WI + +K Sbjct: 393 GNYTKLSKFIPWIKRIMRQK 412 >4IGD-A nrPDB Length = 406 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/263 (30%), Positives = 124/263 (47%), Gaps = 44/263 (16%) Query: 31 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCVG------------ 77 I G+ A + PW L ++G FCGGSL+ W++TAAHC+ Sbjct: 156 IFNGRPAQKGTTPWIAMLSHLNG---QPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRD 212 Query: 78 ------PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPV 131 D K + +LR +Q L V +HPQ+ D+AL+EL E Sbjct: 213 SDLLSPSDFKIILGKHWRLRSDE---NEQHLGVKHTTLHPQYDPNTFENDVALVELLESP 269 Query: 132 NVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP--LKQVKVPIMENHICD 189 +++ V + LP + G V+GWG ++ FP L ++++PI+++ C Sbjct: 270 VLNAFVMPICLPEGPQQ--EGAMVIVSGWG-----KQFLQRFPETLMEIEIPIVDHSTCQ 322 Query: 190 AKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVC--KVNGTWLQAGVVSWG 245 AY ++ RD M+CAG +D+C GDSGGP+V + G W G VSWG Sbjct: 323 K-----AYAPLKKKVTRD-MICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG 376 Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268 + C + +R G+Y+ + + DWI Sbjct: 377 DDCGKKDRYGVYSYIHHNKDWIQ 399 >4DJZ-B nrPDB Length = 251 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 80/263 (30%), Positives = 124/263 (47%), Gaps = 44/263 (16%) Query: 31 IVGGQEAPRSKWPWQVSL-RVHGPYWMHFCGGSLIHPQWVLTAAHCVG------------ 77 I G+ A + PW L ++G FCGGSL+ W++TAAHC+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNG---QPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 78 ------PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPV 131 D K + +LR +Q L V +HPQ+ D+AL+EL E Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDE---NEQHLGVKHTTLHPQYDPNTFENDVALVELLESP 114 Query: 132 NVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP--LKQVKVPIMENHICD 189 +++ V + LP + G V+GWG ++ FP L ++++PI+++ C Sbjct: 115 VLNAFVMPICLPEGPQQ--EGAMVIVSGWG-----KQFLQRFPETLMEIEIPIVDHSTCQ 167 Query: 190 AKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVC--KVNGTWLQAGVVSWG 245 AY ++ RD M+CAG +D+C GDSGGP+V + G W G VSWG Sbjct: 168 K-----AYAPLKKKVTRD-MICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG 221 Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268 + C + +R G+Y+ + + DWI Sbjct: 222 DDCGKKDRYGVYSYIHHNKDWIQ 244 >3BEU-A nrPDB Length = 224 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 110/240 (45%), Gaps = 26/240 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V L + CGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P F G D AL++L +P+N + T TF Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTFT 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + +V ++M+ Sbjct: 114 ------VAGWGA--NREGGSQQRYLLKANVPFVSDAACRSSSSF--------ILVANEMI 157 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNG-TWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG + D+CQGDSGGP+ K N W+Q G+VSWGEGCA+ + G+YT V+ + I Sbjct: 158 CAGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAI 217 >1ORF-A nrPDB Length = 234 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 76/243 (31%), Positives = 119/243 (48%), Gaps = 23/243 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQ 89 I+GG E P+ V L + C G+LI WVLTAAHC + + + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 57 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 RE+ Q++ V + +P + A D+ LL+L E ++ +V + LP + Sbjct: 58 TREEP---TKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDV 114 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PG C V GWG N L++V++ I++ +C+ + H Y + V + +M Sbjct: 115 KPGTMCQVAGWGRTHNSASWSD--TLREVEITIIDRKVCNDRNH---YNFNPV--IGMNM 167 Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVT-YYL 264 +CAG+ R RDSC GDSG PL+C+ + GV S+G C P PG+Y ++ +L Sbjct: 168 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 223 Query: 265 DWI 267 +WI Sbjct: 224 NWI 226 >1M9U-A nrPDB Length = 241 Score = 106 bits (265), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/247 (31%), Positives = 116/247 (46%), Gaps = 20/247 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG A ++PWQ+S + W H CG SL+ L+A+HCV + + + L Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQF--YTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 +Q Q V +H + TA DIA+L L +++ ++ LP + Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C ++GWG D LP L++ +P++ C A A G + D+ Sbjct: 121 DYAGTTCVISGWGRTDGTNNLPD--ILQKSSIPVITTAQCTA-----AMVGVGGANIWDN 173 Query: 209 MLC----AGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSW----GEGCAQPNRPGIYTRV 260 +C AGNT +C GDSGGPL C GT + GV SW G G P+ P +YTRV Sbjct: 174 HICVQDPAGNT--GACNGDSGGPLNCPDGGTRV-VGVTSWVVSSGLGACLPDYPSVYTRV 230 Query: 261 TYYLDWI 267 + YL WI Sbjct: 231 SAYLGWI 237 >4KKD-A nrPDB Length = 433 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 86/270 (31%), Positives = 128/270 (47%), Gaps = 41/270 (15%) Query: 31 IVGGQEAPRSKWPWQV------SLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLA 84 I+GG+ A +PWQ + RV W F G+L+ W+LTAAH + +D Sbjct: 155 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKW--FGSGALLSASWILTAAHVLRSQRRDTT 212 Query: 85 ALRVQLREQHLYY-----QDQLLPV----SRIIVHPQFYTAQIGADIALLELEEPVNVSS 135 + V +Y +D+ V +R+++HP F DIAL++L+EPV + Sbjct: 213 VIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 272 Query: 136 HVHTVTLPPASETFP-PGMPCWVTGWG----DVDNDERLPPPFP-----LKQVKVPIMEN 185 HV V LP P P M V GWG +V DE + L+ VK+P++ + Sbjct: 273 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 332 Query: 186 HICDAKYH--LGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVC--KVNGTWLQA 239 C Y G Y+ V ++M CAG +D+C GDSG V ++ W+ Sbjct: 333 AECKTSYESRSGNYS------VTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQ 386 Query: 240 GVVSWG--EGCAQPNRPGIYTRVTYYLDWI 267 G+VSWG E C G+YT+V+ Y+DW+ Sbjct: 387 GLVSWGGPEECGSKQVYGVYTKVSNYVDWV 416 >2RDL-A nrPDB Length = 226 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/241 (30%), Positives = 119/241 (49%), Gaps = 24/241 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGP-YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E P+ L + P + C G LI +V+TAAHC G + L + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 ++ + Q L V + HP++ + DI LL+L+E N++ V T+ + S + Sbjct: 61 KVKEDTW---QKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSI 117 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PPG C GWG + +E PP L++VK+ I++ C H + ++ Sbjct: 118 PPGRVCRAVGWGRTNVNE--PPSDTLQEVKMRILDPQACK---HFEDFH-------QEPQ 165 Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 LC GN + R+ +GDSGGPL+C + G+ S+ A+P P ++TR+++Y WI Sbjct: 166 LCVGNPKKIRNVYKGDSGGPLLC----AGIAQGIASYVLRNAKP--PSVFTRISHYRPWI 219 Query: 268 H 268 + Sbjct: 220 N 220 >1IAU-A nrPDB Length = 227 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 115/250 (46%), Gaps = 31/250 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG EA P+ L + + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q+ Q +PV R I HP + DI LL+LE + V + LP Sbjct: 55 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG + L++VK+ + E+ C++ D+R D Sbjct: 115 QVKPGQTCSVAGWGQTAPLGKH--SHTLQEVKMTVQEDRKCES----------DLRHYYD 162 Query: 208 DM--LCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 LC G+ ++ S +GDSGGPLVC + G+VS+G P P T+V+ + Sbjct: 163 STIELCVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSF 216 Query: 264 LDWIHHYVPK 273 + WI + + Sbjct: 217 VHWIKKTMKR 226 >4E7N-A nrPDB Length = 238 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 128/249 (51%), Gaps = 29/249 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E ++ + V+L + FCGG+LI+ +WVLTAAHC D K+ +++ + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTL-FCGGTLINQEWVLTAAHC---DRKNF-RIKLGM 55 Query: 91 REQHLYYQDQ--LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ +P + DI L+ L+ PV S H+ +LP + + Sbjct: 56 HSKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPS 115 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDA---KYHLGAYTGDDVRIV 205 G C + GWG + E P P V + ++E +C A ++ L A + Sbjct: 116 V--GSVCRIMGWGRISPTEGTYPDVP-HCVNINLLEYEMCRAPYPEFELPATS------- 165 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTY 262 LCAG +D+C+GDSGGPL+C NG + G+ SWG+ CAQP++P YT+V Sbjct: 166 --RTLCAGILEGGKDTCKGDSGGPLIC--NGQF--QGIASWGDDPCAQPHKPAAYTKVFD 219 Query: 263 YLDWIHHYV 271 +LDWI + + Sbjct: 220 HLDWIENII 228 >1NPM-A nrPDB Length = 225 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 119/246 (48%), Gaps = 35/246 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G+E PWQ +L G + CGG L+ +WVLTAAHC V+L Sbjct: 1 ILEGRECIPHSQPWQAAL-FQGERLI--CGGVLVGDRWVLTAAHC------KKQKYSVRL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQ---IGADIALLELEEPVNVSSHVHTVTLPP 144 + L +D Q + V++ I HP + + DI L+ L+ N+ V V L Sbjct: 52 GDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL-- 109 Query: 145 ASETFPPGMPCWVTGWGDVDN-DERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 A+ G C ++GWG V + E P +VK I + C+ AY G Sbjct: 110 ANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVK--IYSQNKCER-----AYPGK--- 159 Query: 204 IVRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVT 261 + + M+CAG++ D+CQGDSGGPLVC + G+ SWG C +P +PG+YT++ Sbjct: 160 -ITEGMVCAGSSNGADTCQGDSGGPLVCD----GMLQGITSWGSDPCGKPEKPGVYTKIC 214 Query: 262 YYLDWI 267 Y WI Sbjct: 215 RYTTWI 220 >2AIQ-A nrPDB Length = 231 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 119/250 (47%), Gaps = 38/250 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + + +G CGG+LI+ +WVLTA HC D +R+ L Sbjct: 1 VIGGDECNINEHRFLALVYANG----SLCGGTLINQEWVLTARHC------DRGNMRIYL 50 Query: 91 REQHL--YYQDQL--LPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 +L +D L P + DI L+ L PV S+H+ ++LP Sbjct: 51 GMHNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLP--- 107 Query: 147 ETFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 + PP G C + GWG + + P P + I++ +C A Y A T Sbjct: 108 -SNPPSVGSVCRIMGWGTITSPNATLPDVP-HCANINILDYAVCQAAYKGLAAT------ 159 Query: 205 VRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVT 261 LCAG +D+C+GDSGGPL+C NG + G++S G CAQP +PGIYT+V Sbjct: 160 ----TLCAGILEGGKDTCKGDSGGPLIC--NGQF--QGILSVGGNPCAQPRKPGIYTKVF 211 Query: 262 YYLDWIHHYV 271 Y DWI + Sbjct: 212 DYTDWIQSII 221 >2ZKS-A nrPDB Length = 240 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 76/243 (31%), Positives = 120/243 (49%), Gaps = 23/243 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+E P+ SL+ +G H CGG L+HP+WVLTAAHC+ + +A LR+ L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGS---HLCGGVLVHPKWVLTAAHCLA---QRMAQLRLVL 54 Query: 91 REQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 L + I HP++ + D+ALL+L+ V S + + LP + Sbjct: 55 GLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 114 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAKYHLGAYTGDDVRIVRDD 208 G C + GWG RL L+++ + +++ +C ++++ G+ + Sbjct: 115 AAGTRCSMAGWGLTHQGGRL--SRVLRELDLQVLDTRMCNNSRFWNGSLS--------PS 164 Query: 209 MLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLD 265 M+C +D C+GDSGGPLVC G L AGV+S+ C +P + T V Y+ Sbjct: 165 MVCLAADSKDQAPCKGDSGGPLVCG-KGRVL-AGVLSFSSRVCTDIFKPPVATAVAPYVS 222 Query: 266 WIH 268 WI Sbjct: 223 WIR 225 >1AO5-A nrPDB Length = 237 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 119/258 (46%), Gaps = 36/258 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG ++ PWQV++ H CGG L+ WVLTAAHC D ++ + +L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKL 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT-----------AQIGADIALLELEEPVNVSSHVHT 139 ++ Q +L VS+ HP F A D+ LL L +P +++ V Sbjct: 57 FQEEPSAQHRL--VSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKP 114 Query: 140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 199 + LP ++ PG C +GWG + R P L+ V + ++ N C Y Sbjct: 115 IALP--TKEPKPGSKCLASGWGSI-TPTRWQKPDDLQCVFITLLPNENCAKVY------- 164 Query: 200 DDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGI 256 ++ V D MLCAG +D+C+ DSGGPL+C + G S+G C +P P I Sbjct: 165 --LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAI 218 Query: 257 YTRVTYYLDWIHHYVPKK 274 YT + + WI + K Sbjct: 219 YTNLIKFNSWIKDTMMKN 236 >2OLG-A nrPDB Length = 278 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 78/263 (29%), Positives = 121/263 (46%), Gaps = 31/263 (11%) Query: 31 IVGGQEAPRSKWPW--QVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAAL- 86 I+ G + ++PW + + + CGGSLI+ ++++TAAHCV G ++ + AL Sbjct: 23 ILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGALN 82 Query: 87 RVQLREQHLYYQDQL--------------LPVSRIIVHPQFYTAQIGA--DIALLELEEP 130 +V+L E + L + I HP + DIAL+ L Sbjct: 83 KVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLNRQ 142 Query: 131 VNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDA 190 V ++++ V LP +E G V GWG + + +++ VP++ C Sbjct: 143 VEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK---QKLAVPVVHAEQCAK 199 Query: 191 KYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGC 248 + VR VR LCAG + +DSC GDSGGPL+ + N + G+VS+G C Sbjct: 200 TFGAAG-----VR-VRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGATC 253 Query: 249 AQPNRPGIYTRVTYYLDWIHHYV 271 PGIYT+V Y DWI + Sbjct: 254 GTEGWPGIYTKVGKYRDWIEGNI 276 >1OP0-A nrPDB Length = 234 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 127/248 (51%), Gaps = 31/248 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + V+ + FCGG+LI+P+WV+TAAHC D + +++ + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGF---FCGGTLINPEWVVTAAHCDSTDFQ----MQLGV 53 Query: 91 REQHLYYQDQLL--PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ P + I + + DI L++L++P++ S H+ ++LP + + Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPS 113 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY--HLGAYTGDDVRIVR 206 G C + GWG + + P P + ++++ +C A Y L Y Sbjct: 114 V--GSVCRIMGWGSITPVKETFPDVPY-CANINLLDHAVCQAGYPELLAEYR-------- 162 Query: 207 DDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYY 263 LCAG + +D+C GDSGGPL+C NG + G+VS+G C Q +PGIYT V Y Sbjct: 163 --TLCAGIVQGGKDTCGGDSGGPLIC--NGQF--QGIVSYGAHPCGQGPKPGIYTNVFDY 216 Query: 264 LDWIHHYV 271 DWI + Sbjct: 217 TDWIQRNI 224 >4Q7Y-A nrPDB Length = 250 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 117/248 (47%), Gaps = 34/248 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E P+ S+R G H CGG L+ +WV++AAHC +DL V L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCF--SHRDLRTGLVVL 55 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + Q+ + + HP ++ DI LL L + V + L P Sbjct: 56 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRL-PGRR 114 Query: 148 TFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDA--KYHLGAYTGDDVR 203 PP G C V GWG V + E LPP L + KV +++ +C++ K HL Sbjct: 115 ARPPTAGTRCRVAGWGFVSDFEELPP--GLMEAKVRVLDPDVCNSSWKGHLTL------- 165 Query: 204 IVRDDMLC--AGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSW-GEGCAQPNRPGIYTR 259 MLC +G++ RR C DSGGPLVC+ G+VS+ G C P P +YT+ Sbjct: 166 ----TMLCTRSGDSHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQ 217 Query: 260 VTYYLDWI 267 V+ ++ WI Sbjct: 218 VSAFVAWI 225 >1SGF-A nrPDB Length = 240 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 112/258 (43%), Gaps = 36/258 (13%) Query: 32 VGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLR 91 V Q + PW V++ Y CGG L+ WVLTAAHC + L Sbjct: 5 VQSQVDCENSQPWHVAVYRFNKYQ---CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLE 61 Query: 92 EQHLYYQDQLLPVSRIIVHPQFYTAQIGA-----------DIALLELEEPVNVSSHVHTV 140 ++ DQ VS+ I HP F + + D+ LL L +P +++ V + Sbjct: 62 DEP---SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPI 118 Query: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200 TLP +E G C +GWG + P L+ V + ++ N CD + + Sbjct: 119 TLP--TEEPKLGSTCLASGWGST-TPIKFKYPDDLQCVNLKLLPNEDCDKAHEMK----- 170 Query: 201 DVRIVRDDMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIY 257 V D MLCAG S C+ DSGGPL+C + G+ SWG E C +P P +Y Sbjct: 171 ----VTDAMLCAGEMDGGSYTCEHDSGGPLICD----GILQGITSWGPEPCGEPTEPSVY 222 Query: 258 TRVTYYLDWIHHYVPKKP 275 T++ + WI + P Sbjct: 223 TKLIKFSSWIRETMANNP 240 >3S9B-A nrPDB Length = 234 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 78/247 (31%), Positives = 126/247 (51%), Gaps = 29/247 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG E ++ P+ V+L +H C G+LI+ +WVLTAAHC +++ +++ + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCDRRNIR----IKLGM 55 Query: 91 REQHLYYQDQLLPVSR---IIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 +++ +D+ + V R ++ +F + DI L+ L PV S+H+ V+LP S Sbjct: 56 HSKNIRNEDEQIRVPRGKYFCLNTKFPNG-LDKDIMLIRLRRPVTYSTHIAPVSLPSRSR 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C + GWG + P P + I+++ C+ Y + D R Sbjct: 115 GV--GSRCRIMGWGKISTTTY--PDVP-HCTNIFIVKHKWCEPLY---PWVPADSR---- 162 Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYL 264 LCAG + RD+C GDSGGPL+C NG G+V+ G E C Q +P +YT+V Y Sbjct: 163 -TLCAGILKGGRDTCHGDSGGPLIC--NGE--MHGIVAGGSEPCGQHLKPAVYTKVFDYN 217 Query: 265 DWIHHYV 271 +WI + Sbjct: 218 NWIQSII 224 >1Q3X-A nrPDB Length = 328 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 85/263 (32%), Positives = 127/263 (48%), Gaps = 22/263 (8%) Query: 20 PAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG 77 P G + + G I GGQ+A +PWQV L + G G+L++ WVLTAAH V Sbjct: 74 PVCGLSARTTGGRIYGGQKAKPGDFPWQV-LILGGTT----AAGALLYDNWVLTAAHAVY 128 Query: 78 PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEPVNVSS 135 D +AL +++ S + + YT G DIAL++L V ++S Sbjct: 129 EQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINS 188 Query: 136 HVHTVTLP-PASETFPPGMPCWV-TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH 193 ++ + LP +E+F +GWG +R L V +PI+++ C A Y Sbjct: 189 NITPICLPRKEAESFMRTDDIGTASGWGLT---QRGFLARNLMYVDIPIVDHQKCTAAYE 245 Query: 194 LGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGE-GC 248 Y V +MLCAG + +DSC+GDSGG LV + T W G+VSWG C Sbjct: 246 KPPYPRGSVTA---NMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC 302 Query: 249 AQPNRPGIYTRVTYYLDWIHHYV 271 + + G+YT+V Y+ WI + + Sbjct: 303 GEAGQYGVYTKVINYIPWIENII 325 >5XRF-A nrPDB Length = 242 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 125/252 (49%), Gaps = 31/252 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + + P W C G+LIH +WVL AAHC K + + + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRP-WTFQCAGTLIHEEWVLAAAHCY----KRGLNIYLGM 61 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT-----AQIGADIALLELEEPVNVSSHVHTVTLPPA 145 Q + + D+ R + +Y + D+ LL+L +PV+ S+H+ ++LP + Sbjct: 62 HNQSIQFDDEQ---RRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSS 118 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 + G C V GWG + + + + P P + ++ C A Y D Sbjct: 119 PPSI--GSVCRVMGWGIMSSTKDILPDVP-HCANINLLNYMECVAHY------PDVPETT 169 Query: 206 RDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTY 262 R +LCAG D+C DSGGPL+C +G + G+V +G+ CAQPN+PG+YTRV+ Sbjct: 170 R--LLCAGVLEGGIDTCNQDSGGPLIC--DGQF--QGIVFFGKYPCAQPNKPGLYTRVSN 223 Query: 263 YLDWIHHYVPKK 274 Y DWI + + K Sbjct: 224 YNDWIQNIIAGK 235 >4FXG-H nrPDB Length = 242 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 81/251 (32%), Positives = 122/251 (48%), Gaps = 20/251 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GGQ+A +PWQV L + G G+L++ WVLTAAH V D +AL +++ Sbjct: 1 IYGGQKAKPGDFPWQV-LILGGTT----AAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEPVNVSSHVHTVTLP-PASE 147 S + + YT G DIAL++L V ++S++ + LP +E Sbjct: 56 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 115 Query: 148 TFPPGMPCWV-TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 +F +GWG +R L V +PI+++ C A Y Y V Sbjct: 116 SFMRTDDIGTASGWGLT---QRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTA-- 170 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGE-GCAQPNRPGIYTRVT 261 +MLCAG + +DSC+GD+GG LV + T W G+VSWG C + + G+YT+V Sbjct: 171 -NMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVI 229 Query: 262 YYLDWIHHYVP 272 Y+ WI + + Sbjct: 230 NYIPWIENIIS 240 >2FMJ-A nrPDB Length = 222 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 112/240 (46%), Gaps = 28/240 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V L + CGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P + G D AL++L +P+N + T TF Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPINQPTLKIATTTAYNQGTFT 111 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + Y G++ +V ++ + Sbjct: 112 ------VAGWGA--NREGGSQQRYLLKANVPFVSDAACRSAY------GNE--LVANEEI 155 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNG-TWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG D+CQGDSGGP+ K N W+Q G+VSWGEGCA+ + G+YT V+ + I Sbjct: 156 CAGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAI 215 >1ZJK-A nrPDB Length = 403 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 85/263 (32%), Positives = 127/263 (48%), Gaps = 22/263 (8%) Query: 20 PAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG 77 P G + + G I GGQ+A +PWQV L + G G+L++ WVLTAAH V Sbjct: 149 PVCGLSARTTGGQIYGGQKAKPGDFPWQV-LILGGTT----AAGALLYDNWVLTAAHAVY 203 Query: 78 PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEPVNVSS 135 D +AL +++ S + + YT G DIAL++L V ++S Sbjct: 204 EQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINS 263 Query: 136 HVHTVTLP-PASETFPPGMPCWV-TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH 193 ++ + LP +E+F +GWG +R L V +PI+++ C A Y Sbjct: 264 NITPICLPRKEAESFMRTDDIGTASGWGLT---QRGFLARNLMYVDIPIVDHQKCTAAYE 320 Query: 194 LGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGT--WLQAGVVSWGE-GC 248 Y V +MLCAG + +DSC+GDSGG LV + T W G+VSWG C Sbjct: 321 KPPYPRGSVTA---NMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC 377 Query: 249 AQPNRPGIYTRVTYYLDWIHHYV 271 + + G+YT+V Y+ WI + + Sbjct: 378 GEAGQYGVYTKVINYIPWIENII 400 >1BQY-A nrPDB Length = 234 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 70/219 (31%), Positives = 110/219 (50%), Gaps = 24/219 (10%) Query: 58 FCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLL--PVSRIIVHPQFYT 115 CGG+LI+ WV+TAAHC + + L + + + +D+ P + + Sbjct: 25 LCGGTLINQDWVVTAAHCDSNNFQ----LLFGVHSKKILNEDEQTRDPKEKFFCPNRKKD 80 Query: 116 AQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPL 175 ++ DI L++L+ V+ S H+ ++LP + + G C + GWG + + P P Sbjct: 81 DEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSV--GSVCRIMGWGKTIPTKEIYPDVP- 137 Query: 176 KQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVN 233 + I+++ +C Y R V + LCAG + RD+C DSGGPL+C N Sbjct: 138 HCANINILDHAVCRTAYSW--------RQVANTTLCAGILQGGRDTCHFDSGGPLIC--N 187 Query: 234 GTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLDWIHHYV 271 G + G+VSWG C QP PG+YT+V YLDWI + Sbjct: 188 GIF--QGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >3VGC-B nrPDB Length = 131 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 51/131 (38%), Positives = 72/131 (54%), Gaps = 4/131 (3%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IV G+EA WPWQVSL+ + HFCGGSLI+ WV+TAAHC G D+ + + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGF--HFCGGSLINENWVVTAAHC-GVTTSDVV-VAGEF 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + + Q L ++++ + ++ + I DI LL+L + S V V LP AS+ F Sbjct: 57 DQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 116 Query: 151 PGMPCWVTGWG 161 G C TGWG Sbjct: 117 AGTTCVTTGWG 127 >5UBM-A nrPDB Length = 252 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 118/257 (45%), Gaps = 39/257 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG +A +PWQV P+ GG+LI+ WVLTAAH V + + + Sbjct: 2 IIGGSDADIKNFPWQVFF--DNPW----AGGALINEYWVLTAAHVVEGNREPTMYVGSTS 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQI-------GADIALLELEEPVNVSSHVHTVTLP 143 + + ++L + +HP + ++ DIAL+ L++PV + V + LP Sbjct: 56 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 115 Query: 144 PASETFP--PGMPCWVTGWGDVDNDERLP-------PPFPLKQVKVPIMENHICDAKYHL 194 S + G ++GWG + +R P PL++ K +E DA+ + Sbjct: 116 GTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY- 174 Query: 195 GAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCK---VNGTWLQAGVVSWGEGCAQ 250 + +M+CAG + DSC+GDSGG + + AG+VSWG C Sbjct: 175 ---------VFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT 225 Query: 251 PNRPGIYTRVTYYLDWI 267 G+YTRV Y+DWI Sbjct: 226 ---YGLYTRVKNYVDWI 239 >1GVZ-A nrPDB Length = 237 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 81/265 (30%), Positives = 117/265 (44%), Gaps = 48/265 (18%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHF-CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E + PWQV++ G HF CGG L+HPQWVLTAAHC+ D ++ Sbjct: 1 IIGGWECEKHSKPWQVAVYHQG----HFQCGGVLVHPQWVLTAAHCMSDDY------QIW 50 Query: 90 LREQHLYYQD---QLLPVSRIIVHPQFYTA-----------QIGADIALLELEEPVNVSS 135 L +L + Q VS + PQF + I D+ LL L +P ++ Sbjct: 51 LGRHNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITD 110 Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195 V + LP G C+ +GWG + L+ V++ + N C Y Sbjct: 111 AVKILDLPTQEPKL--GSTCYTSGWGLISTFTNRGSG-TLQCVELRLQSNEKCARAY--- 164 Query: 196 AYTGDDVRIVRDDMLCAGNTRRDS----CQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQ 250 + + +LCA T RD C GDSGG L+C +G + G+ SWG CA Sbjct: 165 ------PEKMTEFVLCA--THRDDSGSICLGDSGGALIC--DGVF--QGITSWGYSECAD 212 Query: 251 PNRPGIYTRVTYYLDWIHHYVPKKP 275 N ++T+V + WI + K Sbjct: 213 FNDNFVFTKVMPHKKWIKETIEKNS 237 >5LPF-A nrPDB Length = 234 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 111/248 (44%), Gaps = 33/248 (13%) Query: 34 GQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ 93 G R PWQVSL + C G L+ WVLTAAHC K L A RV Sbjct: 7 GSPCARGSQPWQVSLFNGLSF---HCAGVLVDQSWVLTAAHCGN---KPLWA-RVGDDHL 59 Query: 94 HLYYQDQLLPVSRIIVHPQFYTAQ--------IGADIALLELEEPVNVSSHVHTVTLPPA 145 L +QL +R +VHP+++ D+ LL+L PV + V + LP Sbjct: 60 LLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLP-- 117 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 PG C V GWG R+ L + I+ C+ Y +V Sbjct: 118 YRCAQPGDQCQVAGWG-TTAARRVKYNKGLTCSSITILSPKECEVFYP---------GVV 167 Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYY 263 ++M+CAG R +D CQ DSGGPLVC LQ G++SWG C P +YT++ Y Sbjct: 168 TNNMICAGLDRGQDPCQSDSGGPLVCDET---LQ-GILSWGVYPCGSAQHPAVYTQICKY 223 Query: 264 LDWIHHYV 271 + WI+ + Sbjct: 224 MSWINKVI 231 >1ELV-A nrPDB Length = 333 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 116/259 (44%), Gaps = 27/259 (10%) Query: 22 PGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVK 81 P + QR I+GG +A +PWQV P+ GG+LI+ WVLTAAH V + + Sbjct: 76 PFEEKQR--IIGGSDADIKNFPWQVFF--DNPW----AGGALINEYWVLTAAHVVEGNRE 127 Query: 82 DLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-------TAQIGADIALLELEEPVNVS 134 + + + ++L + +HP + DIAL+ L++PV + Sbjct: 128 PTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMG 187 Query: 135 SHVHTVTLPPASETFP--PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192 V + LP S + G ++GWG + +R LK ++P+ C Sbjct: 188 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRA---VRLKAARLPVAPLRKCKEVK 244 Query: 193 HLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCK---VNGTWLQAGVVSWGEGC 248 + + +M+CAG + DSC+GDSGG + + AG+VSWG C Sbjct: 245 VEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC 304 Query: 249 AQPNRPGIYTRVTYYLDWI 267 G+YTRV Y+DWI Sbjct: 305 GT---YGLYTRVKNYVDWI 320 >1AE5-A nrPDB Length = 225 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 113/245 (46%), Gaps = 40/245 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-----GPDVKDLAA 85 IVGG++A ++P+ S++ G HFCGG+LIH ++V+TAA C G L A Sbjct: 1 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 ++ RE+ + +S PQ Q D+ LL+L+ N++S V + LP Sbjct: 58 YDLRRRERQSRQTFSISSMSENGYDPQ----QNLNDLMLLQLDREANLTSSVTILPLPLQ 113 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 + T G C V GWG + RL FP + V V + C Sbjct: 114 NATVEAGTRCQVAGWGSQRSGGRL-SRFP-RFVNVTVTPEDQC----------------- 154 Query: 206 RDDMLCAGN-TRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTY 262 R + +C G TRR C GD G PLVC+ L GV S+ G C + P +TRV Sbjct: 155 RPNNVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVAL 208 Query: 263 YLDWI 267 + DWI Sbjct: 209 FRDWI 213 >4J1Y-A nrPDB Length = 397 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 71/254 (27%), Positives = 115/254 (45%), Gaps = 25/254 (9%) Query: 27 QRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAAL 86 ++ +GG +A +PWQV P+ GG+LI+ WVLTAAH V + + + Sbjct: 143 EKARAIGGSDADIKNFPWQVFF--DNPW----AGGALINEYWVLTAAHVVEGNREPTMYV 196 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQI-------GADIALLELEEPVNVSSHVHT 139 + + ++L + +HP + ++ DIAL+ L++PV + V Sbjct: 197 GSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSP 256 Query: 140 VTLPPASETFP--PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 + LP S + G ++GWG + +R LK ++P+ C Sbjct: 257 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDRA---VRLKAARLPVAPLRKCKEVKVEKPT 313 Query: 198 TGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCK---VNGTWLQAGVVSWGEGCAQPNR 253 + + +M+CAG + DSC+GDSGG + + AG+VSWG C Sbjct: 314 ADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT--- 370 Query: 254 PGIYTRVTYYLDWI 267 G+YTRV Y+DWI Sbjct: 371 YGLYTRVKNYVDWI 384 >2JET-B nrPDB Length = 128 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 50/128 (39%), Positives = 69/128 (53%), Gaps = 4/128 (3%) Query: 34 GQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ 93 G++A WPWQVSL+ + HFCGGSLI WV+TAAHC G D+ + + + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGF--HFCGGSLISEDWVVTAAHC-GVKTSDVV-VAGEFDQG 56 Query: 94 HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGM 153 Q+L ++++ +P+F + DI LL+L P S V V LP + FPPG Sbjct: 57 SDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGT 116 Query: 154 PCWVTGWG 161 C TGWG Sbjct: 117 VCATTGWG 124 >2XXL-A nrPDB Length = 408 Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 78/264 (29%), Positives = 111/264 (42%), Gaps = 41/264 (15%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHF-CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 + G E S PW LR F CGG++I +++LTAAHCV DL +R Sbjct: 119 VSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR-- 176 Query: 90 LREQHLYYQDQL---------------LPVSRIIVHPQFYTAQIGADIALLELEEPVNVS 134 L E + ++ + + + ++H ++ I DIALL+L V Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQ 236 Query: 135 SHVHTVTLPPASETFPPGMPC---WVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK 191 H+ + LP E +VTGWG +N L Q VP+ C Sbjct: 237 KHIKPICLPITDELKEKAEQISTYFVTGWGTTENGS---SSDVLLQANVPLQPRSACSQA 293 Query: 192 YHLGAYTGDDVRIVRDDMLC-AGNTRRDSCQGDSGGPL------VCKVNGTWLQAGVVSW 244 Y R V LC G +DSC+GDSGGPL + + ++ G+VS Sbjct: 294 YR---------RAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQ 344 Query: 245 G-EGCAQPNRPGIYTRVTYYLDWI 267 G C Q + PG+YT V Y+ WI Sbjct: 345 GVVTCGQISLPGLYTNVGEYVQWI 368 >2HLC-A nrPDB Length = 230 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 76/248 (30%), Positives = 117/248 (47%), Gaps = 33/248 (13%) Query: 31 IVGGQEAPRSKWPWQ----VSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAAL 86 I+ G EA +P+Q ++L+ W CGGSLI +W+LTAAHC V D ++ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVW---CGGSLIDNKWILTAAHC----VHDAVSV 53 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 V L Y + ++ RII H F D+AL+++ V + ++ + LP Sbjct: 54 VVYLGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGE 112 Query: 147 ETFPPGMPCW--VTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 E W V+GWG + D + L+ +++N C +Y G I Sbjct: 113 ELNNKFENIWATVSGWGQSNTDTVI-----LQYTYNLVIDNDRCAQEYPPG--------I 159 Query: 205 VRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVT 261 + + +C + S C GDSGGP V ++ L GVVS+ G GC + +P ++RVT Sbjct: 160 IVESTICGDTSDGKSPCFGDSGGPFV--LSDKNLLIGVVSFVSGAGC-ESGKPVGFSRVT 216 Query: 262 YYLDWIHH 269 Y+DWI Sbjct: 217 SYMDWIQQ 224 >5XW8-A nrPDB Length = 133 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 50/136 (36%), Positives = 74/136 (54%), Gaps = 15/136 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 9 IVGGYTCAANSIPYQVSLN----SGSHFCGGSLINSQWVVSAAHCYK------SRIQVRL 58 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP F + DI L++L P ++S V TV+LP + Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 148 TFPPGMPCWVTGWGDV 163 G C ++GWG+ Sbjct: 119 --AAGTECLISGWGNT 132 >4F4O-C nrPDB Length = 347 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 76/267 (28%), Positives = 125/267 (46%), Gaps = 41/267 (15%) Query: 22 PGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAA------HC 75 P +QR I+GG + +PWQ + H G +LI+ QW+LT A H Sbjct: 96 PVDQVQR--IMGGSLDAKGSFPWQAKMISHHNL---TSGATLINEQWLLTTAKNLRLGHK 150 Query: 76 VGPDVKDLA-ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVS 134 KD+A LR+ + ++ Q + + ++I HP T DI L++L++ V V+ Sbjct: 151 NDTKAKDIAPTLRLYVGKK------QEVEIEKVIFHPDNSTV----DIGLIKLKQKVPVN 200 Query: 135 SHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHL 194 V + LP + + G+ +V+GWG + L LK V +P+ + C +Y+ Sbjct: 201 ERVMPICLP-SKDYVNVGLVGYVSGWG---RNANLNFTEHLKYVMLPVADQEKC-VQYYE 255 Query: 195 GAYTGDDVR---------IVRDDMLCAGNTR--RDSCQGDSGGPLVC--KVNGTWLQAGV 241 G+ + I+ + CAG ++ D+C GD+G K + TW AG+ Sbjct: 256 GSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGI 315 Query: 242 VSWGEGCAQPNRPGIYTRVTYYLDWIH 268 +S+ + C + G+Y RVT LDWI Sbjct: 316 LSFDKSC-RTAEYGVYVRVTSILDWIQ 341 >3S69-A nrPDB Length = 234 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/246 (28%), Positives = 117/246 (47%), Gaps = 27/246 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ V+ + FC G+LI+ +WVLTAAHC + + +++ + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGF---FCSGTLINEEWVLTAAHCDNTNFQ----MKLGV 53 Query: 91 REQHLYYQDQLL--PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ P + I + + DI L++L+ V+ S H+ V L S Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSP 111 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C + GWG + + P P + ++++ +C A Y + Sbjct: 112 PSVGSVCHIMGWGSITPIKVTYPDVPY-CAYINLLDDAVCQAGY--------PELLTEYR 162 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLD 265 LCAG +D+C GDSGGPL+C NG + G+VS+G C Q +PG+YT+V Y Sbjct: 163 TLCAGILEGGKDTCGGDSGGPLIC--NGQF--QGIVSFGAHPCGQGLKPGVYTKVFDYNH 218 Query: 266 WIHHYV 271 WI + Sbjct: 219 WIQSII 224 >2PKA-B nrPDB Length = 152 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 54/159 (33%), Positives = 81/159 (50%), Gaps = 19/159 (11%) Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVD-NDERLPPPFPLKQVK 179 D+ LL L+ P ++ V + LP G C +GWG ++ + P ++ V+ Sbjct: 9 DLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFPDEIQCVQ 66 Query: 180 VPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWL 237 + +++N C A H V + MLCAG +D+C GDSGGPL+C NG W Sbjct: 67 LTLLQNTFC-ADAHPDK--------VTESMLCAGYLPGGKDTCMGDSGGPLIC--NGMW- 114 Query: 238 QAGVVSWGEG-CAQPNRPGIYTRVTYYLDWIHHYVPKKP 275 G+ SWG C N+P IYT++ +YLDWI + + P Sbjct: 115 -QGITSWGHTPCGSANKPSIYTKLIFYLDWIDDTITENP 152 >3RU4-E nrPDB Length = 96 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 40/100 (40%), Positives = 56/100 (56%), Gaps = 9/100 (9%) Query: 172 PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCK 231 P L+Q +P++ N C K + G ++D M+CAG + SC GDSGGPLVCK Sbjct: 3 PDRLQQASLPLLSNTNC--KKYWGTK-------IKDAMICAGASGVSSCMGDSGGPLVCK 53 Query: 232 VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271 NG W G+VSWG + PG+Y RVT ++W+ + Sbjct: 54 KNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 40/103 (38%), Positives = 55/103 (53%), Gaps = 9/103 (8%) Query: 169 LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPL 228 L P L+Q +PI+ C + + D M CAG + DSC GDSGGPL Sbjct: 3 LKTPEKLQQAALPIVSEADCKKSWG---------SKITDVMTCAGASGVDSCMGDSGGPL 53 Query: 229 VCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271 VC+ +G W AG+VSWG G + PG+Y+RVT + W+ + Sbjct: 54 VCQKDGVWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQIL 96 >4X0L-C nrPDB Length = 259 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 70/272 (25%), Positives = 124/272 (45%), Gaps = 41/272 (15%) Query: 22 PGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAA------HC 75 P +QR I+GG + +PWQ + H G +LI+ QW+LT A H Sbjct: 8 PANPVQR--ILGGHLDAKGSFPWQAKMVSHHNL---TTGATLINEQWLLTTAKNLFLNHS 62 Query: 76 VGPDVKDLAALRVQLREQHLYY-QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVS 134 KD+A LY + QL+ + ++++HP + +Q+ DI L++L++ V+V+ Sbjct: 63 ENATAKDIAPTLT------LYVGKKQLVEIEKVVLHPNY--SQV--DIGLIKLKQKVSVN 112 Query: 135 SHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHL 194 V + L P+ + G +V+GWG + LK V +P+ + C +++ Sbjct: 113 ERVMPICL-PSKDYAEVGRVGYVSGWG---RNANFKFTDHLKYVMLPVADQDQC-IRHYE 167 Query: 195 GAYTGDDVR---------IVRDDMLCAGNTR--RDSCQGDSGGPLVCK--VNGTWLQAGV 241 G+ + I+ + CAG ++ D+C GD+G TW G+ Sbjct: 168 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 227 Query: 242 VSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 +S+ + CA G+Y +VT DW+ + + Sbjct: 228 LSFDKSCAVAEY-GVYVKVTSIQDWVQKTIAE 258 >4WJG-C nrPDB Length = 315 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/272 (25%), Positives = 124/272 (45%), Gaps = 41/272 (15%) Query: 22 PGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAA------HC 75 P +QR I+GG + +PWQ + H G +LI+ QW+LT A H Sbjct: 64 PANPVQR--ILGGHLDAKGSFPWQAKMVSHHNLTT---GATLINEQWLLTTAKNLFLNHS 118 Query: 76 VGPDVKDLAALRVQLREQHLYY-QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVS 134 KD+A LY + QL+ + ++++HP + +Q+ DI L++L++ V+V+ Sbjct: 119 ENATAKDIAPTLT------LYVGKKQLVEIEKVVLHPNY--SQV--DIGLIKLKQKVSVN 168 Query: 135 SHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHL 194 V + L P+ + G +V+GWG + LK V +P+ + C +++ Sbjct: 169 ERVMPICL-PSKDYAEVGRVGYVSGWG---RNANFKFTDHLKYVMLPVADQDQC-IRHYE 223 Query: 195 GAYTGDDVR---------IVRDDMLCAGNTR--RDSCQGDSGGPLVCK--VNGTWLQAGV 241 G+ + I+ + CAG ++ D+C GD+G TW G+ Sbjct: 224 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 283 Query: 242 VSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 +S+ + CA G+Y +VT DW+ + + Sbjct: 284 LSFDKSCAVAEY-GVYVKVTSIQDWVQKTIAE 314 >1AKS-B nrPDB Length = 98 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 47/102 (46%), Positives = 64/102 (62%), Gaps = 15/102 (14%) Query: 172 PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLV 229 P L+ +K P++ N C + Y G TG+ M+C G + +DSCQGDSGGP+V Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYP-GQITGN--------MICVGFLQGGKDSCQGDSGGPVV 57 Query: 230 CKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271 C NG LQ G+VSWG GCAQ N+PG+YT+V Y++WI + Sbjct: 58 C--NGQ-LQ-GIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >1PPF-E nrPDB Length = 218 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 108/249 (43%), Gaps = 40/249 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-----VGPDVKDLAA 85 IVGG+ A WP+ VSL++ G HFCG +LI P +V++AAHC V L A Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 + RE Q+ V RI + + DI +L+L ++++V LP Sbjct: 58 HNLSRREP----TRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQ 112 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 G+ C GWG + + + L+++ V ++ + + Sbjct: 113 GRRLGNGVQCLAMGWGLLGRNRGIAS--VLQELNVTVVTS------------------LC 152 Query: 206 RDDMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTY 262 R +C R + C GDSG PLVC NG L G+ S+ GCA P + V Sbjct: 153 RRSNVCTLVRGRQAGVCFGDSGSPLVC--NG--LIHGIASFVRGGCASGLYPDAFAPVAQ 208 Query: 263 YLDWIHHYV 271 +++WI + Sbjct: 209 FVNWIDSII 217 >2I6S-A nrPDB Length = 517 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 31/242 (12%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88 VG + + + + PW V+++ P C G+LI QWVLTAAHC D D + RV Sbjct: 230 VGNMSANASDQERTPWHVTIK---PKSQETCRGALISDQWVLTAAHCF-RDGNDHSLWRV 285 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQF---------YTAQIGADIALLELEEPVNVSSHVHT 139 + + + + L + + ++ P F G DIALL+L + V +S+H Sbjct: 286 NVGDPKSQWGKEFL-IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARP 344 Query: 140 VTLPPASETF-----PPGMPCWVTGWGDVDNDERLPPPF-PLKQVKVPIMEN-------- 185 + LP E P G C ++ N + +P F L K+ I Sbjct: 345 ICLPCTMEANLALRRPQGSTCR-DHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSC 403 Query: 186 -HICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVS 243 + + + D +V D LC+G +S C+G+SGG + + + Q G+VS Sbjct: 404 AEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVS 463 Query: 244 WG 245 WG Sbjct: 464 WG 465 >1BBR-H nrPDB Length = 150 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 50/144 (34%), Positives = 76/144 (52%), Gaps = 13/144 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-------GPDVKD- 82 IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ V D Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I +HP++ + + DIALL+L+ P+ +S ++H V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGD 162 LP A++ G VTGWG+ Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGN 143 >1BBR-E nrPDB Length = 109 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 42/109 (38%), Positives = 56/109 (51%), Gaps = 16/109 (14%) Query: 172 PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGG 226 P L+ V +P++E +C A +RI D+M CAG R D+C+GDSGG Sbjct: 7 PSVLQVVNLPLVERPVCKASTR--------IRIT-DNMFCAGYKPGEGKRGDACEGDSGG 57 Query: 227 PLVCK--VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 P V K N W Q G+VSWGEGC + + G YT V WI + + Sbjct: 58 PFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2HNT-F nrPDB Length = 105 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 43/110 (39%), Positives = 56/110 (50%), Gaps = 18/110 (16%) Query: 172 PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI-VRDDMLCAG-----NTRRDSCQGDSG 225 P L+ V +PI+E +C D RI + D+M CAG R D+C+GDSG Sbjct: 3 PSVLQVVNLPIVERPVCK----------DSTRIRITDNMFCAGYKPDEGKRGDACEGDSG 52 Query: 226 GPLVCK--VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GP V K N W Q G+VSWGEGC + + G YT V WI + + Sbjct: 53 GPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >1RIW-B nrPDB Length = 147 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 50/145 (34%), Positives = 75/145 (51%), Gaps = 13/145 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAALRV 88 IV G +A PWQV L P + CG SLI +WVLTAAHC+ P K+ + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 89 QLR---EQHLYYQDQLLPVS---RIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVT 141 +R Y+ + +S +I +HP++ + + DIAL++L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDV 163 LP A+ G VTGWG++ Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNL 144 >1DLE-A nrPDB Length = 298 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 68/267 (25%), Positives = 108/267 (40%), Gaps = 52/267 (19%) Query: 18 AAPAPGQALQRVGIV--GGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAH 74 A P Q+L G+V + K PWQ + V P H C G+++ +VLTAAH Sbjct: 1 ADPDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAH 60 Query: 75 CVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY---TAQIGA------DIALL 125 C D K+ +++V + + + L + ++ HP + + G D+AL+ Sbjct: 61 CFTVDDKE-HSIKVSVGGEK-----RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALI 114 Query: 126 ELEEPVNVSSHVHTVTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180 +L+ + + + LP T PP C E L P +K + V Sbjct: 115 KLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFV 167 Query: 181 PIMENHIC-----------------DAKYHLGAYTGDDV-RIVRDDMLCAGNTRR----D 218 E + DA+Y G D+ +V LC G + Sbjct: 168 SEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPN 227 Query: 219 SCQGDSGGPLVCKVNGTWLQAGVVSWG 245 +C+GDSGGPL+ ++Q GV+SWG Sbjct: 228 TCRGDSGGPLIVHKRSRFIQVGVISWG 254 >2WIN-I nrPDB Length = 507 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 62/242 (25%), Positives = 99/242 (40%), Gaps = 50/242 (20%) Query: 41 KWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD 99 K PWQ + V P H C G+++ +VLTAAHC D K+ +++V + + Sbjct: 233 KQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKE-HSIKVSVGGEK----- 286 Query: 100 QLLPVSRIIVHPQFY---TAQIGA------DIALLELEEPVNVSSHVHTVTLPPASET-- 148 + L + ++ HP + + G D+AL++L+ + + + LP T Sbjct: 287 RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 346 Query: 149 ---FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC----------------- 188 PP C E L P +K + V E + Sbjct: 347 ALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 399 Query: 189 DAKYHLGAYTGDDV-RIVRDDMLCAGNTRR----DSCQGDSGGPLVCKVNGTWLQAGVVS 243 DA+Y G D+ +V LC G ++C+GDSGGPL+ ++Q GV+S Sbjct: 400 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 459 Query: 244 WG 245 WG Sbjct: 460 WG 461 >2OK5-A nrPDB Length = 752 Score = 64.7 bits (156), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 62/242 (25%), Positives = 99/242 (40%), Gaps = 50/242 (20%) Query: 41 KWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD 99 K PWQ + V P H C G+++ +VLTAAHC D K+ +++V + + Sbjct: 477 KQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKE-HSIKVSVGGEK----- 530 Query: 100 QLLPVSRIIVHPQFY---TAQIGA------DIALLELEEPVNVSSHVHTVTLPPASET-- 148 + L + ++ HP + + G D+AL++L+ + + + LP T Sbjct: 531 RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 590 Query: 149 ---FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC----------------- 188 PP C E L P +K + V E + Sbjct: 591 ALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 643 Query: 189 DAKYHLGAYTGDDV-RIVRDDMLCAGNTRR----DSCQGDSGGPLVCKVNGTWLQAGVVS 243 DA+Y G D+ +V LC G ++C+GDSGGPL+ ++Q GV+S Sbjct: 644 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 703 Query: 244 WG 245 WG Sbjct: 704 WG 705 >3H7T-A nrPDB Length = 235 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 61/248 (24%), Positives = 111/248 (44%), Gaps = 21/248 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+++ +K PW V + V FCGGS++ +V+TAA CV D + + + Sbjct: 1 IIGGKKSDITKEPWAVGVLVD---EKPFCGGSILTANFVITAAQCV--DGTKPSDISIHY 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSH-VHTVTLPPASETF 149 + + + +I + +++ + + A++E E P+ + + LP Sbjct: 56 GSSYRTTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDP 114 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 P V+GWG N + L L + +++ C+ +Y D + + D + Sbjct: 115 EPDTSVLVSGWGST-NFKSLEYSGDLMEANFTVVDRKSCEEQYK--QIEAD--KYIYDGV 169 Query: 210 LCAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNR-PGIYTRVTYYLDW 266 CAG ++ GD+G P V NGT + GV S+ + P+ P ++ RV YY+ Sbjct: 170 FCAGGEYDETYIGYGDAGDPAV--QNGTLV--GVASY--ISSMPSEFPSVFLRVGYYVLD 223 Query: 267 IHHYVPKK 274 I + K Sbjct: 224 IKDIISGK 231 >3H7O-A nrPDB Length = 228 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 100/244 (40%), Gaps = 19/244 (7%) Query: 33 GGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLRE 92 GG++ + PW V++R + CGG+++ +VLTAAHCV + + +Q Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPE--TIVIQYES 59 Query: 93 QHLYYQDQLLPVSRIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPP 151 +L+ V+ FY + + DIA+LEL P+ + P E P Sbjct: 60 TNLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 152 -GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G V+G+GD + P LK ++ +++ C KY + + Sbjct: 120 TGSDVLVSGYGDGQTMD--PKDHDLKSAQLTVVDLDECRTKYG--------PIFLSLQVF 169 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CA GD+G P V + + A EG P ++T+V Y+ WI Sbjct: 170 CAQKVGVSLESGDAGDPTVQQDTLVGVAAYFPKRPEGA-----PEVFTKVGSYVSWIQDI 224 Query: 271 VPKK 274 + KK Sbjct: 225 IKKK 228 >2KAI-A nrPDB Length = 80 Score = 50.8 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 21/45 (46%), Positives = 32/45 (71%), Gaps = 3/45 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC 75 I+GG+E ++ PWQV++ + + CGG L++P+WVLTAAHC Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQ---CGGVLVNPKWVLTAAHC 42 >1EPT-B nrPDB Length = 82 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%) Query: 87 RVQLR-EQH----LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVT 141 R+Q+R +H L +Q + ++II HP F + DI L++L P ++S V TV+ Sbjct: 2 RIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 61 Query: 142 LPPASETFPPGMPCWVTGWGD 162 LP + G C ++GWG+ Sbjct: 62 LPRSCAA--AGTECLISGWGN 80 >2HNT-E nrPDB Length = 81 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 38/64 (59%), Gaps = 4/64 (6%) Query: 104 VSRIIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVTLP---PASETFPPGMPCWVTG 159 + +I +HP++ + + DIAL++L++PV S ++H V LP A+ G VTG Sbjct: 8 LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTG 67 Query: 160 WGDV 163 WG++ Sbjct: 68 WGNL 71 >2HNT-C nrPDB Length = 70 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/46 (50%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 IV G +A PWQV L P + CG SLI +WVLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCL 45 >3F1S-B nrPDB Length = 283 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ-HLYYQDQL 101 PWQV L FCGG +I +VLT A C L + ++ + QD L Sbjct: 65 PWQVKLT--NSEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPL 116 Query: 102 L-PVSRIIVHPQFYTAQIGADIALLELEEPV 131 + ++ + VH ++ D++LLELE P+ Sbjct: 117 MIKITHVHVHMRYDADAGENDLSLLELEWPI 147 >3H5C-B nrPDB Length = 317 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ-HLYYQDQL 101 PWQV L FCGG +I +VLT A C L + ++ + QD L Sbjct: 106 PWQVKLT--NSEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPL 157 Query: 102 L-PVSRIIVHPQFYTAQIGADIALLELEEPV 131 + ++ + VH ++ D++LLELE P+ Sbjct: 158 MIKITHVHVHMRYDADAGENDLSLLELEWPI 188 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4MPW-A nrPDB 363 e-101 1LTO-A nrPDB 351 2e-97 2F83-A nrPDB 280 5e-76 1YC0-A nrPDB 279 1e-75 5TJX-A nrPDB 279 1e-75 6I44-A nrPDB 278 2e-75 1F7Z-A nrPDB 278 2e-75 4AN7-A nrPDB 276 7e-75 5GVT-A nrPDB 274 3e-74 5FXL-A nrPDB 273 7e-74 3DFJ-A nrPDB 271 2e-73 4WWY-A nrPDB 271 2e-73 3E0N-B nrPDB 271 3e-73 1UTJ-A nrPDB 271 3e-73 5C67-A nrPDB 269 6e-73 1A0J-A nrPDB 269 6e-73 1EKB-B nrPDB 269 1e-72 6AOD-C nrPDB 269 1e-72 4DGJ-A nrPDB 268 1e-72 1PYT-D nrPDB 266 1e-71 2CGA-A nrPDB 264 2e-71 3W94-A nrPDB 264 4e-71 2TLD-E nrPDB 264 4e-71 1X7A-C nrPDB 263 5e-71 4H4F-A nrPDB 262 1e-70 1FXY-A nrPDB 261 2e-70 3T2N-A nrPDB 261 3e-70 1BRU-P nrPDB 260 4e-70 3LC3-A nrPDB 260 5e-70 2F91-A nrPDB 259 1e-69 5UGG-A nrPDB 258 2e-69 3K65-B nrPDB 258 2e-69 3NXP-A nrPDB 257 3e-69 1MKW-K nrPDB 257 3e-69 1BDA-A nrPDB 256 7e-69 1P57-B nrPDB 256 7e-69 4NZQ-A nrPDB 256 8e-69 1EUF-A nrPDB 256 8e-69 4DUR-A nrPDB 256 1e-68 3P8G-A nrPDB 255 1e-68 1SGF-G nrPDB 255 1e-68 2OCV-B nrPDB 255 2e-68 1KIG-H nrPDB 253 5e-68 1SC8-U nrPDB 252 1e-67 4NFE-A nrPDB 252 1e-67 1VR1-H nrPDB 252 1e-67 1C5M-D nrPDB 252 1e-67 1ETT-H nrPDB 251 2e-67 2V35-A nrPDB 249 7e-67 2OQ5-A nrPDB 249 1e-66 2R0L-A nrPDB 249 1e-66 2EEK-A nrPDB 247 3e-66 3F6U-H nrPDB 247 3e-66 1FI8-A nrPDB 247 3e-66 4Z6A-H nrPDB 247 5e-66 5LHN-A nrPDB 245 1e-65 1A5I-A nrPDB 245 1e-65 1SPJ-A nrPDB 244 5e-65 1FIZ-A nrPDB 242 9e-65 1ELT-A nrPDB 242 9e-65 5MS3-A nrPDB 242 1e-64 1FIW-A nrPDB 242 1e-64 3BSQ-A nrPDB 241 3e-64 1IAU-A nrPDB 241 3e-64 1ELV-A nrPDB 241 3e-64 5UBM-A nrPDB 240 5e-64 3QUM-P nrPDB 239 7e-64 5TO3-B nrPDB 239 1e-63 1NPM-A nrPDB 239 1e-63 2PSX-A nrPDB 238 2e-63 5ZFH-A nrPDB 237 5e-63 1Q3X-A nrPDB 236 8e-63 1NN6-A nrPDB 236 9e-63 6QHB-A nrPDB 236 1e-62 3TK9-A nrPDB 235 1e-62 4J1Y-A nrPDB 234 3e-62 1FDP-A nrPDB 234 3e-62 1ZJK-A nrPDB 234 3e-62 4XDE-A nrPDB 234 4e-62 1FON-A nrPDB 233 5e-62 4KKD-A nrPDB 233 6e-62 5FCR-A nrPDB 233 8e-62 1AO5-A nrPDB 233 8e-62 3G01-A nrPDB 232 8e-62 4FXG-H nrPDB 232 1e-61 2XRC-A nrPDB 232 1e-61 2B9L-A nrPDB 232 1e-61 1TON-A nrPDB 231 2e-61 6BQM-A nrPDB 231 3e-61 4IW4-E nrPDB 230 6e-61 1YM0-A nrPDB 228 2e-60 1SGF-A nrPDB 227 3e-60 1GPZ-A nrPDB 227 5e-60 5O32-I nrPDB 225 2e-59 1FUJ-A nrPDB 224 2e-59 1MD7-A nrPDB 224 3e-59 4E7N-A nrPDB 224 4e-59 4BXW-A nrPDB 224 4e-59 2QY0-B nrPDB 224 4e-59 4GSO-A nrPDB 224 5e-59 2OLG-A nrPDB 222 1e-58 1MZD-A nrPDB 221 2e-58 1KYN-A nrPDB 221 3e-58 4IGD-A nrPDB 220 7e-58 2BDH-A nrPDB 219 1e-57 2AIQ-A nrPDB 219 1e-57 4DJZ-B nrPDB 218 2e-57 1ORF-A nrPDB 218 2e-57 3RP2-A nrPDB 217 5e-57 3S9B-A nrPDB 217 6e-57 2RDL-A nrPDB 216 9e-57 1GVZ-A nrPDB 215 2e-56 1BQY-A nrPDB 214 2e-56 3I77-A nrPDB 214 2e-56 1EQ9-A nrPDB 214 3e-56 5LPF-A nrPDB 213 5e-56 2ZKS-A nrPDB 213 6e-56 1OP0-A nrPDB 213 6e-56 4LK4-A nrPDB 213 8e-56 4Q7Y-A nrPDB 212 1e-55 2XXL-A nrPDB 212 1e-55 3BEU-A nrPDB 210 5e-55 3S69-A nrPDB 209 1e-54 1AZZ-A nrPDB 208 2e-54 2ASU-B nrPDB 205 2e-53 4X0L-C nrPDB 205 2e-53 4WJG-C nrPDB 204 4e-53 4F4O-C nrPDB 203 8e-53 1PQ7-A nrPDB 202 1e-52 2FMJ-A nrPDB 201 3e-52 5KWM-A nrPDB 199 1e-51 1M9U-A nrPDB 196 7e-51 5XRF-A nrPDB 194 5e-50 2HLC-A nrPDB 191 3e-49 1SI5-H nrPDB 189 1e-48 1PPF-E nrPDB 184 4e-47 1AE5-A nrPDB 181 3e-46 3H7O-A nrPDB 176 8e-45 1DLE-A nrPDB 173 1e-43 3H7T-A nrPDB 170 5e-43 2WIN-I nrPDB 170 6e-43 2PKA-B nrPDB 168 3e-42 2OK5-A nrPDB 166 1e-41 2I6S-A nrPDB 163 5e-41 5XW8-A nrPDB 153 5e-38 3VGC-B nrPDB 153 8e-38 2JET-B nrPDB 150 9e-37 1RIW-B nrPDB 143 9e-35 1BBR-H nrPDB 138 2e-33 1AKS-B nrPDB 128 3e-30 1BBR-E nrPDB 123 7e-29 2HNT-F nrPDB 123 1e-28 3RU4-E nrPDB 120 9e-28 2JET-C nrPDB 120 9e-28 1EPT-B nrPDB 98 3e-21 2KAI-A nrPDB 90 1e-18 2HNT-E nrPDB 83 2e-16 2HNT-C nrPDB 69 2e-12 Sequences not found previously or not previously below threshold: 3F1S-B nrPDB 94 5e-20 3H5C-B nrPDB 92 3e-19 1P3E-A nrPDB 42 3e-04 5ILB-A nrPDB 33 0.13 4FLN-A nrPDB 33 0.13 4JCN-A nrPDB 32 0.23 2OUA-A nrPDB 31 0.67 5LAK-A nrPDB 30 1.0 2SFA-A nrPDB 30 1.1 2PFE-A nrPDB 30 1.4 4NCX-A nrPDB 29 1.9 3AK5-A nrPDB 29 2.8 5OJX-A nrPDB 28 3.2 3LT3-A nrPDB 28 3.6 2EA3-A nrPDB 28 5.0 6F07-A nrPDB 27 9.2 >4MPW-A nrPDB Length = 245 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 244/245 (99%), Positives = 244/245 (99%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPV VSSHVHTVTLPPASETFP Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFP 120 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML Sbjct: 121 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 180 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY Sbjct: 181 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 240 Query: 271 VPKKP 275 VPKKP Sbjct: 241 VPKKP 245 >1LTO-A nrPDB Length = 245 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 228/245 (93%), Positives = 234/245 (95%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQEAPRSKWPWQVSLRV YWMHFCGGSLIHPQWVLTAAHC+GPDVKDLA LRVQL Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 REQHLYYQDQLLPVSRIIVHPQFY Q GADIALLELEEPVN+SS VHTV LPPASETFP Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETFP 120 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PGMPCWVTGWGDVDNDE LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI+RDDML Sbjct: 121 PGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDML 180 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CAGN++RDSC+GDSGGPLVCKVNGTWLQAGVVSW EGCAQPNRPGIYTRVTYYLDWIHHY Sbjct: 181 CAGNSQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDWIHHY 240 Query: 271 VPKKP 275 VPKKP Sbjct: 241 VPKKP 245 >2F83-A nrPDB Length = 625 Score = 280 bits (716), Expect = 5e-76, Method: Composition-based stats. Identities = 97/257 (37%), Positives = 129/257 (50%), Gaps = 14/257 (5%) Query: 15 RAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAH 74 R + IVGG + R +WPWQV+L P H CGGS+I QW+LTAAH Sbjct: 372 RLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAH 431 Query: 75 CVGP--DVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVN 132 C K L L + + V II+H Q+ A+ G DIALL+LE VN Sbjct: 432 CFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVN 491 Query: 133 VSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192 + + LP + CWVTGWG +++ L++ K+P++ N C +Y Sbjct: 492 YTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKI--QNTLQKAKIPLVTNEECQKRY 549 Query: 193 HLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQ 250 + M+CAG +D+C+GDSGGPL CK N W G+ SWGEGCAQ Sbjct: 550 R--------GHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQ 601 Query: 251 PNRPGIYTRVTYYLDWI 267 RPG+YT V Y+DWI Sbjct: 602 RERPGVYTNVVEYVDWI 618 >1YC0-A nrPDB Length = 283 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 86/280 (30%), Positives = 133/280 (47%), Gaps = 24/280 (8%) Query: 5 LLLALPVLAS---RAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGG 61 LL LP AS +A + R I+GG + PW ++ + FC G Sbjct: 7 LLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS----FCAG 62 Query: 62 SLIHPQWVLTAAHCVG--PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQ-I 118 SL+H WV++AAHC P ++ + Q Q + + I + + Sbjct: 63 SLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPS 122 Query: 119 GADIALLELEEP----VNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174 D+ L+ L++ S V + LP TFP G C + GWG +D + Sbjct: 123 DHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSS-S 181 Query: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKV 232 L++ VP++ +H C + GA + +MLCAG + + D+CQGDSGGPL C+ Sbjct: 182 LREALVPLVADHKCSSPEVYGAD-------ISPNMLCAGYFDCKSDACQGDSGGPLACEK 234 Query: 233 NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 272 NG G++SWG+GC + ++PG+YTRV Y+DWI+ + Sbjct: 235 NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 274 >5TJX-A nrPDB Length = 263 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 92/243 (37%), Positives = 127/243 (52%), Gaps = 14/243 (5%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAAL 86 IVGG E+ +WPWQVSL+V H CGGSLI QWVLTAAHC P Sbjct: 14 TRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L + + II+H + ++ DIAL++L+ P+ + ++LP Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKG 133 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 +T CWVTGWG + L++V +P++ N C +Y + Sbjct: 134 DTSTIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRYQD--------YKIT 183 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 M+CAG +D+C+GDSGGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+ Sbjct: 184 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYM 243 Query: 265 DWI 267 DWI Sbjct: 244 DWI 246 >6I44-A nrPDB Length = 627 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 90/243 (37%), Positives = 127/243 (52%), Gaps = 14/243 (5%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAAL 86 IVGG ++ +WPWQVSL+V H CGGSLI QWVLTAAHC P Sbjct: 378 TRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 437 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L+ + + II+H + ++ DIAL++L+ P+ + + LP Sbjct: 438 SGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSKG 497 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 +T CWVTGWG + L++V +P++ N C +Y + Sbjct: 498 DTSTIYTNCWVTGWGFSAEAGEI--QNILQKVNIPLVTNEECQKRYQD--------YKIT 547 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 M+CAG +D+C+GD+GGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+ Sbjct: 548 QRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYM 607 Query: 265 DWI 267 DWI Sbjct: 608 DWI 610 >1F7Z-A nrPDB Length = 233 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 91/249 (36%), Positives = 133/249 (53%), Gaps = 31/249 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 11 IVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCYK------SRIQVRL 60 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP F + DI L++L PV +++ V TV LP + Sbjct: 61 GEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS-- 118 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P G C ++GWG+ + + P L+ + P++ C+A Y + D Sbjct: 119 CAPAGTQCLISGWGNTLSSG-VNEPDLLQCLDAPLLPQADCEASY---------PGKITD 168 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M+C G +DSCQGDSGGP+VC G+VSWG GCA P+ PG+YT+V Y+D Sbjct: 169 NMVCVGFLEGGKDSCQGDSGGPVVCNGE----LQGIVSWGYGCALPDNPGVYTKVCNYVD 224 Query: 266 WIHHYVPKK 274 WI + Sbjct: 225 WIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 89/250 (35%), Positives = 132/250 (52%), Gaps = 31/250 (12%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+ Sbjct: 8 KIVGGYTCAANSIPYQVSLNSGS----HFCGGSLINSQWVVSAAHCYK------SRIQVR 57 Query: 90 LREQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L E + L +Q + ++II HP F + DI L++L P ++S V TV+LP + Sbjct: 58 LGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS- 116 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 G C ++GWG+ + P L+ +K P++ + C + Y + Sbjct: 117 -CAAAGTECLISGWGNTKSSGSSYPSL-LQCLKAPVLSDSSCKSSY---------PGQIT 165 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 +M+C G +DSCQGDSGGP+VC G+VSWG GCAQ N+PG+YT+V Y+ Sbjct: 166 GNMICVGFLEGGKDSCQGDSGGPVVCN----GQLQGIVSWGYGCAQKNKPGVYTKVCNYV 221 Query: 265 DWIHHYVPKK 274 +WI + Sbjct: 222 NWIQQTIAAN 231 >5GVT-A nrPDB Length = 250 Score = 274 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 94/242 (38%), Positives = 133/242 (54%), Gaps = 16/242 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG A +WPWQVSL+V H CGGS+I QWVLTAAHC + R+ Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDG-IPYPDVWRIYG 59 Query: 91 REQHLYYQDQLLPVSRI---IVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + P SRI I+H ++ ++ DIAL++L+ P+N + ++LP ++ Sbjct: 60 GILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 T CWVTGWG L++ +P++ N C KY ++ Sbjct: 120 TNTIYTNCWVTGWGYTKEQGE--TQNILQKATIPLVPNEECQKKYRD--------YVINK 169 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M+CAG D+C+GDSGGPLVCK +G W G+ SWGEGCA+ ++PG+YT+V+ Y+D Sbjct: 170 QMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMD 229 Query: 266 WI 267 WI Sbjct: 230 WI 231 >5FXL-A nrPDB Length = 246 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 88/250 (35%), Positives = 135/250 (54%), Gaps = 31/250 (12%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+ Sbjct: 23 KIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYK------SGIQVR 72 Query: 90 LREQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L E ++ +Q + S+ IVHP + + + DI L++L+ +++S V +++LP + Sbjct: 73 LGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSC 132 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + G C ++GWG+ + P LK +K PI+ + C + Y + Sbjct: 133 AS--AGTQCLISGWGNTKSSG-TSYPDVLKCLKAPILSDSSCKSAY---------PGQIT 180 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 +M CAG +DSCQGDSGGP+VC + G+VSWG GCAQ N+PG+YT+V Y+ Sbjct: 181 SNMFCAGYLEGGKDSCQGDSGGPVVC----SGKLQGIVSWGSGCAQKNKPGVYTKVCNYV 236 Query: 265 DWIHHYVPKK 274 WI + Sbjct: 237 SWIKQTIASN 246 >3DFJ-A nrPDB Length = 263 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 102/248 (41%), Positives = 141/248 (56%), Gaps = 10/248 (4%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GG A +WPWQVS+ G +H CGGSL+ QWVL+AAHC P A V+L Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCF-PSEHHKEAYEVKL 56 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L ++ + II HP + DIALL+L P+ S ++ ++LP A+ Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANA 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 +FP G+ C VTGWG V L P PL+Q++VP++ C+A Y++ A ++ V++ Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDA-KPEEPHFVQE 175 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 DM+CAG +D+CQGDSGGPL C V G W G+VSWG+ C NRPG+YT + Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 235 Query: 266 WIHHYVPK 273 WI V + Sbjct: 236 WIQSKVTE 243 >4WWY-A nrPDB Length = 224 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 87/250 (34%), Positives = 130/250 (52%), Gaps = 31/250 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++A HC + ++V+L Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCYK------SRIQVRL 50 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HPQ+ + DI L++L +++HV T++LP A Sbjct: 51 GEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAP- 109 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C ++GWG+ + P L+ + P++ C+A Y + Sbjct: 110 -PATGTKCLISGWGNTASSG-ADYPDELQCLDAPVLSQAKCEASY---------PGKITS 158 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M C G +DSCQ DSGGP+VC GVVSWG+GCAQ N+PG+YT+V Y+ Sbjct: 159 NMFCVGFLEGGKDSCQRDSGGPVVCN----GQLQGVVSWGDGCAQKNKPGVYTKVYNYVK 214 Query: 266 WIHHYVPKKP 275 WI + + Sbjct: 215 WIKNTIAANS 224 >3E0N-B nrPDB Length = 271 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 101/248 (40%), Positives = 140/248 (56%), Gaps = 10/248 (4%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GG A +WPWQVS+ G +H CGGSL+ QWVL+AAHC P A V+L Sbjct: 1 ITGGSSAVAGQWPWQVSITYEG---VHVCGGSLVSEQWVLSAAHCF-PSEHHKEAYEVKL 56 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L ++ + II HP + DIALL+L P+ S ++ ++LP A Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQA 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 +FP G+ C VTGWG V L P PL+Q++VP++ C++ Y++ A ++ V++ Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDA-KPEEPHFVQE 175 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 DM+CAG +D+CQGDSGGPL C V G W G+VSWG+ C NRPG+YT + Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 235 Query: 266 WIHHYVPK 273 WI V + Sbjct: 236 WIQSKVTE 243 >1UTJ-A nrPDB Length = 242 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 86/249 (34%), Positives = 126/249 (50%), Gaps = 32/249 (12%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IVGG E P QVSL HFCGGSL++ WV++AAHC + + V+ Sbjct: 20 KIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVVSAAHCYK------SRVEVR 69 Query: 90 LREQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L E + +Q + SR+I HP + + I DI L++L +P ++++V V LP + Sbjct: 70 LGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTS- 128 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 P G C V+GWG+ + L+ + +PI+ C+ Y ++ Sbjct: 129 -CAPAGTMCTVSGWGNTMSST--ADSNKLQCLNIPILSYSDCNNSY---------PGMIT 176 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 + M CAG +DSCQGDSGGP+VC GVVSWG GCA+P PG+Y +V + Sbjct: 177 NAMFCAGYLEGGKDSCQGDSGGPVVCNGE----LQGVVSWGYGCAEPGNPGVYAKVCIFN 232 Query: 265 DWIHHYVPK 273 DW+ + Sbjct: 233 DWLTSTMAS 241 >5C67-A nrPDB Length = 224 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 88/250 (35%), Positives = 126/250 (50%), Gaps = 31/250 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI QWV++AAHC ++V+L Sbjct: 1 IVGGYTCEENSLPYQVSLNSGS----HFCGGSLISEQWVVSAAHCYK------TRIQVRL 50 Query: 91 REQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E + L +Q + ++II HP++ + DI L++L P +++ V T++LP A Sbjct: 51 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAP- 109 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C ++GWG+ + P LK + P++ C A Y + + Sbjct: 110 -PAAGTECLISGWGNTLSFG-ADYPDELKCLDAPVLTQAECKASY---------PGKITN 158 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M C G +DSCQ D+GGP+VC GVVSWG GCA NRPG+YT+V Y+D Sbjct: 159 SMFCVGFLEGGKDSCQRDAGGPVVCN----GQLQGVVSWGHGCAWKNRPGVYTKVYNYVD 214 Query: 266 WIHHYVPKKP 275 WI + Sbjct: 215 WIKDTIAANS 224 >1A0J-A nrPDB Length = 223 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 87/249 (34%), Positives = 135/249 (54%), Gaps = 31/249 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E ++ +Q SL+ HFCGGSLI WV++AAHC + ++V+L Sbjct: 1 IVGGYECRKNSASYQASLQSG----YHFCGGSLISSTWVVSAAHCYK------SRIQVRL 50 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E ++ +Q + ++I+HP + + + DI L++L +P +++S+V TV LP + Sbjct: 51 GEHNIAVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCA 110 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 + G C V+GWG++ + P L+ + +PI+ + C++ Y + Sbjct: 111 S--SGTRCLVSGWGNL-SGSSSNYPDTLRCLDLPILSSSSCNSAY---------PGQITS 158 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M CAG +DSCQGDSGGP+VC GVVSWG GCAQ N+PG+YT+V Y Sbjct: 159 NMFCAGFMEGGKDSCQGDSGGPVVCN----GQLQGVVSWGYGCAQRNKPGVYTKVCNYRS 214 Query: 266 WIHHYVPKK 274 WI + Sbjct: 215 WISSTMSSN 223 >1EKB-B nrPDB Length = 235 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 83/245 (33%), Positives = 125/245 (51%), Gaps = 19/245 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD----VKDLAAL 86 IVGG ++ WPW V+L CG SL+ W+++AAHCV K A L Sbjct: 1 IVGGSDSREGAWPWVVALYFDD---QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + + Q + + +I+++P + + DIA++ LE VN + ++ + LP + Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FPPG C + GWG + L++ VP++ N C + + Sbjct: 118 QVFPPGRICSIAGWGALIYQGS--TADVLQEADVPLLSNEKCQQQMPEYN--------IT 167 Query: 207 DDMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M+CAG DSCQGDSGGPL+C+ N WL AGV S+G CA PNRPG+Y RV + Sbjct: 168 ENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFT 227 Query: 265 DWIHH 269 +WI Sbjct: 228 EWIQS 232 >6AOD-C nrPDB Length = 245 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 94/241 (39%), Positives = 128/241 (53%), Gaps = 14/241 (5%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP--DVKDLAALRV 88 IVGG + R +WPWQV+L P H CGGS+I QW+LTAAHC K L Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 L++ + V II+H Q+ A+ G DIALL+LE V + ++LP + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 CWVTGWG +++ L++ K+P++ N C +Y + Sbjct: 121 NVIYTDCWVTGWGYRKLRDKI--QNTLQKAKIPLVTNEECQKRYR--------GHKITHK 170 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 M+CAG +D+C+GD+GGPL CK N W G+ SWGEGCAQ RPG+YT V Y+DW Sbjct: 171 MICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDW 230 Query: 267 I 267 I Sbjct: 231 I 231 >4DGJ-A nrPDB Length = 235 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 84/245 (34%), Positives = 124/245 (50%), Gaps = 19/245 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD----VKDLAAL 86 IVGG +A WPW V L CG SL+ W+++AAHCV K A L Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRL---LCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + ++ Q + I+++P + + DIA++ LE VN + ++ ++LP + Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FPPG C + GWG V L++ VP++ N C + + Sbjct: 118 QVFPPGRNCSIAGWGTVVYQG--TTADILQEADVPLLSNERCQQQMPEYN--------IT 167 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M+CAG DSCQGDSGGPL+C+ N W AGV S+G CA PNRPG+Y RV+ + Sbjct: 168 ENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFT 227 Query: 265 DWIHH 269 +WI Sbjct: 228 EWIQS 232 >1PYT-D nrPDB Length = 251 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 90/264 (34%), Positives = 134/264 (50%), Gaps = 22/264 (8%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRV-HGPYWMHFCGGSLIHPQWVLTAAHC 75 AP Q +VGG++A WPWQ+SL+ W H CGG+LI P VLTAAHC Sbjct: 1 CGAPI-FQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHC 59 Query: 76 VGPDVKDLAALRVQLREQHLYYQDQ----LLPVSRIIVHPQFYTAQIGADIALLELEEPV 131 + + RV L + +L +D+ + V I VH ++ + + DIAL++L E V Sbjct: 60 IS----NTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETV 115 Query: 132 NVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK 191 + + LP P PC+VTGWG + + P L+Q P+++ C + Sbjct: 116 ELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNG--PIAAELQQGLQPVVDYATCSQR 173 Query: 192 YHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG--C 248 G V++ M+CAG +C GDSGGPL C+ +G W G+VS+G G C Sbjct: 174 DWWG-------TTVKETMVCAGGDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSC 226 Query: 249 AQPNRPGIYTRVTYYLDWIHHYVP 272 +P ++TRV+ Y+DWI+ + Sbjct: 227 NTFKKPTVFTRVSAYIDWINQKLQ 250 >2CGA-A nrPDB Length = 245 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 87/245 (35%), Positives = 124/245 (50%), Gaps = 14/245 (5%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IV G+EA WPWQVSL+ + HFCGGSLI+ WV+TAAHC + + Sbjct: 15 RIVNGEEAVPGSWPWQVSLQDKTGF--HFCGGSLINENWVVTAAHC--GVTTSDVVVAGE 70 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + + Q L ++++ + ++ + I DI LL+L + S V V LP AS+ F Sbjct: 71 FDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 130 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 G C TGWG + P L+Q +P++ N C + ++D M Sbjct: 131 AAGTTCVTTGWG-LTRYTNANTPDRLQQASLPLLSNTNCKKYWG---------TKIKDAM 180 Query: 210 LCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHH 269 +CAG + SC GDSGGPLVCK NG W G+VSWG + PG+Y RVT ++W+ Sbjct: 181 ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ 240 Query: 270 YVPKK 274 + Sbjct: 241 TLAAN 245 >3W94-A nrPDB Length = 235 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 90/246 (36%), Positives = 120/246 (48%), Gaps = 19/246 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDL----AAL 86 +VGG A + WPW VSL G H CG SLI W+LTAAHCV L A L Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRG---RHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 87 RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 + + + Q+ V RII++ + ADIA++ L++PVN + V V L Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 + FP G C++ GWG LP L++ +VP+++ C Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLP--DILQEAEVPLVDQDECQR--------LLPEYTFT 167 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 MLCAG DSCQGDSGGPL+C + W GV S+G GC +P RPG Y RV+ + Sbjct: 168 SSMLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFT 227 Query: 265 DWIHHY 270 WI Sbjct: 228 SWIAET 233 >2TLD-E nrPDB Length = 220 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 87/247 (35%), Positives = 133/247 (53%), Gaps = 30/247 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+L Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYK------SGIQVRL 50 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E ++ +Q + S+ IVHP + + + DI L++L+ +++S V +++LP + Sbjct: 51 GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA 110 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 + G C ++GWG+ + P LK +K PI+ + C + Y + Sbjct: 111 S--AGTQCLISGWGNTKSSG-TSYPDVLKCLKAPILSDSSCKSAY---------PGQITS 158 Query: 208 DMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +M CAG DSCQGDSGGP+VC + G+VSWG GCA N+PG+YT+V Y+ WI Sbjct: 159 NMFCAGLEGGDSCQGDSGGPVVC----SGKLQGIVSWGSGCA-KNKPGVYTKVCNYVSWI 213 Query: 268 HHYVPKK 274 + Sbjct: 214 KQTIASN 220 >1X7A-C nrPDB Length = 235 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 89/248 (35%), Positives = 129/248 (52%), Gaps = 21/248 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ A ++PWQV L FCGGS+I+ +WV+TAAHC+ P VK + + + Sbjct: 1 IVGGENAKPGQFPWQVLL---NGKIDAFCGGSIINEKWVVTAAHCIEPGVK-ITVVAGEY 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT--AQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + +Q V R I H + + DIALLEL+EP+ ++S+V + + T Sbjct: 57 NTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYT 116 Query: 149 --FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 F +V+GWG V N R L+ +KVP+++ C + Sbjct: 117 NIFLKFGSGYVSGWGRVFNRGR--SATILQYLKVPLVDRATCLRSTKF---------TIY 165 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 +M CAG +DSCQGDSGGP V +V GT G++SWGE CA + GIYT+V+ Y+ Sbjct: 166 SNMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYV 225 Query: 265 DWIHHYVP 272 +WI Sbjct: 226 NWIKEKTK 233 >4H4F-A nrPDB Length = 249 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 88/251 (35%), Positives = 131/251 (52%), Gaps = 22/251 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRV-HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG++A WPWQ+SL+ W H CGG+LI +VLTAAHC+ + RV Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS----NTRTYRVA 56 Query: 90 LREQHLYYQDQ----LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 + + +L +D+ + V I VH ++ + DIAL++L E V +S + LP Sbjct: 57 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 116 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 P PC+VTGWG + + P L+Q P++++ C G V Sbjct: 117 DSLLPKDYPCYVTGWGRLWTNG--PIADKLQQGLQPVVDHATCSRIDWWGFR-------V 167 Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCK-VNGTWLQAGVVSWG--EGCAQPNRPGIYTRVT 261 + M+CAG +C GDSGGPL C+ NG+W G+VS+G GC +P +YTRV+ Sbjct: 168 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 262 YYLDWIHHYVP 272 Y+DWI+ + Sbjct: 228 AYIDWINEKMQ 238 >1FXY-A nrPDB Length = 228 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 80/250 (32%), Positives = 124/250 (49%), Gaps = 27/250 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + PWQ L FCGG+++ ++LTAAHC+ + +V++ Sbjct: 1 IVGGYNCKDGEVPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKR----FKVRV 54 Query: 91 REQHLYYQDQ---LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 +++ ++ + V +I H +F DIA+L L+ P+ +V +LP A Sbjct: 55 GDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAP- 113 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G C ++GWG+ + P L+ + P++ C+A Y + Sbjct: 114 -PATGTKCLISGWGNTASSG-ADYPDELQCLDAPVLSQAKCEASY---------PGKITS 162 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +M C G +DSCQGDSGGP+VC NG GVVSWG+GCAQ N+PG+YT+V Y+ Sbjct: 163 NMFCVGFLEGGKDSCQGDSGGPVVC--NGQ--LQGVVSWGDGCAQKNKPGVYTKVYNYVK 218 Query: 266 WIHHYVPKKP 275 WI + + Sbjct: 219 WIKNTIAANS 228 >3T2N-A nrPDB Length = 372 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 88/256 (34%), Positives = 127/256 (49%), Gaps = 25/256 (9%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IVGG++ +WPWQVSLR G H CGGSL+ WVLTAAHC + L+ RV Sbjct: 117 RIVGGRDTSLGRWPWQVSLRYDG---AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 173 Query: 90 LREQ-HLYYQDQLLPVSRIIVHPQF------YTAQIGADIALLELEEPVNVSSHVHTVTL 142 L V ++ H + + + DIAL+ L P+ ++ ++ V L Sbjct: 174 AGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 233 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P A + G C VTGWG+ + L++ +VPI+ N +C+ G Sbjct: 234 PAAGQALVDGKICTVTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN------ 285 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG----TWLQAGVVSWGEGCAQPNRPGI 256 ++ M CAG D+CQGDSGGP VC+ + W G+VSWG GCA +PG+ Sbjct: 286 -QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGV 344 Query: 257 YTRVTYYLDWIHHYVP 272 YT+V+ + +WI + Sbjct: 345 YTKVSDFREWIFQAIK 360 >1BRU-P nrPDB Length = 241 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 90/254 (35%), Positives = 135/254 (53%), Gaps = 23/254 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHG-PYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG++A + WPWQVSL+ W H CGG+L+ WVLTAAHC+ RV Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSR----TYRVV 56 Query: 90 LREQHLYYQDQ---LLPVSRIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPP 144 L L + + VS+++VH + + Q+ G DIALL+L PV+++ + LP Sbjct: 57 LGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPA 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A P C+VTGWG + + P L+Q ++ +++ C G+ Sbjct: 117 AGTILPNNYVCYVTGWGRLQTNG--ASPDILQQGQLLVVDYATCSKPGWWGS-------T 167 Query: 205 VRDDMLCAGNTR-RDSCQGDSGGPLVCK-VNGTWLQAGVVSWGE--GCAQPNRPGIYTRV 260 V+ +M+CAG SC GDSGGPL C+ NG W G+VS+G GC ++P ++TRV Sbjct: 168 VKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRV 227 Query: 261 TYYLDWIHHYVPKK 274 + Y+DWI+ + Sbjct: 228 SNYIDWINSVIANN 241 >3LC3-A nrPDB Length = 235 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 86/248 (34%), Positives = 132/248 (53%), Gaps = 21/248 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG++A ++PWQV L FCGGS+++ +W++TAAHCV VK + + + Sbjct: 1 VVGGEDAKPGQFPWQVVL---NGKVDAFCGGSIVNEKWIVTAAHCVETGVK-ITVVAGEH 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT--AQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +Q V RII H + + DIALLEL+EP+ ++S+V + + T Sbjct: 57 NIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYT 116 Query: 149 --FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 F +V+GWG V + R L+ ++VP+++ C + Sbjct: 117 NIFLKFGSGYVSGWGRVFHKGR--SALVLQYLRVPLVDRATCLRSTKF---------TIY 165 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 ++M CAG RDSCQGDSGGP V +V GT G++SWGE CA + GIYT+V+ Y+ Sbjct: 166 NNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYV 225 Query: 265 DWIHHYVP 272 +WI Sbjct: 226 NWIKEKTK 233 >2F91-A nrPDB Length = 237 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 87/245 (35%), Positives = 131/245 (53%), Gaps = 19/245 (7%) Query: 31 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRV 88 IVGG +A ++P+Q+S + + HFCG S+ + + +TA HCV G D ++ + L++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 89 QLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 E + + Q++ VS+II+H F + DI+LL+L + + +V + LP Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 T VTGWG P L++V VP++ + C A Y + Sbjct: 121 GHT--ATGDVIVTGWGTTSEGGNTP--DVLQKVTVPLVSDEDCRADYGADE--------I 168 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 D M+CAG +DSCQGDSGGPL G+ AG+VSWG GCA+P PG+YT V+Y+ Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYH 228 Query: 264 LDWIH 268 +DWI Sbjct: 229 VDWIK 233 >5UGG-A nrPDB Length = 251 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 95/263 (36%), Positives = 132/263 (50%), Gaps = 24/263 (9%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 P +VGG A WPWQVSLR + MHFCGG+LI P+WVLTAAHC+ Sbjct: 8 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCL 65 Query: 77 GPDVKDLAALRVQLREQ---HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNV 133 + ++ +V L +L Q + VSR+ + P DIALL+L P + Sbjct: 66 EKSPRP-SSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVI 118 Query: 134 SSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH 193 + V LP + C++TGWG+ LK+ ++P++EN +C+ Sbjct: 119 TDKVIPACLPSPNYVVADRTECFITGWGETQ---GTFGAGLLKEAQLPVIENKVCNRYEF 175 Query: 194 LGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQP 251 L V+ LCAG DSCQGDSGGPLVC ++ GV SWG GCA+P Sbjct: 176 LNGR-------VQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARP 228 Query: 252 NRPGIYTRVTYYLDWIHHYVPKK 274 N+PG+Y RV+ ++ WI + Sbjct: 229 NKPGVYVRVSRFVTWIEGVMRNN 251 >3K65-B nrPDB Length = 308 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 87/268 (32%), Positives = 127/268 (47%), Gaps = 33/268 (12%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD------ 82 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 48 GRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTEN 106 Query: 83 --LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHT 139 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H Sbjct: 107 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 166 Query: 140 VTLP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKY 192 V LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 167 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--- 223 Query: 193 HLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWG 245 + D+M CAG R D+C+GD+GGP V K N W Q G+VSWG Sbjct: 224 ------DSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWG 277 Query: 246 EGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 EGC + + G YT V WI + + Sbjct: 278 EGCDRDGKYGFYTHVFRLKKWIQKVIDQ 305 >3NXP-A nrPDB Length = 424 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 88/268 (32%), Positives = 127/268 (47%), Gaps = 33/268 (12%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD------ 82 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 164 GRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTEN 222 Query: 83 --LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHT 139 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H Sbjct: 223 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 282 Query: 140 VTLP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKY 192 V LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 283 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--- 339 Query: 193 HLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWG 245 + D+M CAG R D+C+GDSGGP V K N W Q G+VSWG Sbjct: 340 ------DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 393 Query: 246 EGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 EGC + + G YT V WI + + Sbjct: 394 EGCDRDGKYGFYTHVFRLKKWIQKVIDQ 421 >1MKW-K nrPDB Length = 308 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 89/274 (32%), Positives = 130/274 (47%), Gaps = 33/274 (12%) Query: 23 GQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD 82 ++ IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 42 FESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWD 100 Query: 83 --------LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNV 133 L + R ++ +++ + +I +HP++ + DIALL+L+ P+ + Sbjct: 101 KNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIEL 160 Query: 134 SSHVHTVTLP---PASETFPPGMPCWVTGWGDVDNDERLP----PPFPLKQVKVPIMENH 186 S ++H V LP A++ G VTGWG+ P L+ V +P++E Sbjct: 161 SDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERP 220 Query: 187 ICDAKYHLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQA 239 +C A + D+M CAG R D+C+GDSGGP V K N W Q Sbjct: 221 VCKAS---------TRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQM 271 Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 G+VSWGEGC + + G YT V WI + + Sbjct: 272 GIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >1BDA-A nrPDB Length = 265 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 92/273 (33%), Positives = 126/273 (46%), Gaps = 27/273 (9%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAA 73 Q + I GG A + PWQ ++ P CGG LI W+L+AA Sbjct: 2 CGLRQYSQP--QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAA 59 Query: 74 HCVGPDVKDLAALRVQLREQHLY--YQDQLLPVSRIIVHPQFYTAQIGADIALLELE--- 128 HC + R + ++Q V + IVH +F DIALL+L+ Sbjct: 60 HCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDS 119 Query: 129 -EPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187 SS V TV LPPA P C ++G+G + LK+ V + + Sbjct: 120 SRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFY-SERLKEAHVRLYPSSR 178 Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTRR--------DSCQGDSGGPLVCKVNGTWLQA 239 C +++ L R V D+MLCAG+TR D+CQGDSGGPLVC +G Sbjct: 179 CTSQHLLN-------RTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLV 231 Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 272 G++SWG GC Q + PG+YT+VT YLDWI + Sbjct: 232 GIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 264 >1P57-B nrPDB Length = 255 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 127/255 (49%), Gaps = 25/255 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++ +WPWQVSLR G H CGGSL+ WVLTAAHC + L+ RV Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDG---AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 91 REQ-HLYYQDQLLPVSRIIVHPQF------YTAQIGADIALLELEEPVNVSSHVHTVTLP 143 L V ++ H + + + DIAL+ L P+ ++ ++ V LP Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 117 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 A + G C VTGWG+ + L++ +VPI+ N +C+ G Sbjct: 118 AAGQALVDGKICTVTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN------- 168 Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG----TWLQAGVVSWGEGCAQPNRPGIY 257 ++ M CAG D+CQGDSGGP VC+ + W G+VSWG GCA +PG+Y Sbjct: 169 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVY 228 Query: 258 TRVTYYLDWIHHYVP 272 T+V+ + +WI + Sbjct: 229 TKVSDFREWIFQAIK 243 >4NZQ-A nrPDB Length = 557 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 88/268 (32%), Positives = 127/268 (47%), Gaps = 33/268 (12%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD------ 82 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 297 GRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTEN 355 Query: 83 --LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHT 139 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H Sbjct: 356 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 415 Query: 140 VTLP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKY 192 V LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 416 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--- 472 Query: 193 HLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWG 245 + D+M CAG R D+C+GDSGGP V K N W Q G+VSWG Sbjct: 473 ------DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 526 Query: 246 EGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 EGC + + G YT V WI + + Sbjct: 527 EGCDRDGKYGFYTHVFRLKKWIQKVIDQ 554 >1EUF-A nrPDB Length = 227 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 76/248 (30%), Positives = 118/248 (47%), Gaps = 28/248 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG EA P+ L H CGG L+ +VLTAAHC+G +++ V L Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLG------SSINVTL 54 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q++PV R I HP + + DI LL+L +++ V + LP + Sbjct: 55 GAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLA 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PGM C V GWG + +P L++V + + C A++ + Sbjct: 115 EVKPGMMCSVAGWGRL--GVNMPSTDKLQEVDLEVQSEEKCIARFK---------NYIPF 163 Query: 208 DMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +CAG+ R++S GDSGGPLVC + G+VS+G P +YTR++ +L Sbjct: 164 TQICAGDPSKRKNSFSGDSGGPLVCN----GVAQGIVSYGRNDGT--TPDVYTRISSFLS 217 Query: 266 WIHHYVPK 273 WIH + + Sbjct: 218 WIHSTMRR 225 >4DUR-A nrPDB Length = 791 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 95/263 (36%), Positives = 132/263 (50%), Gaps = 24/263 (9%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 P +VGG A WPWQVSLR + MHFCGG+LI P+WVLTAAHC+ Sbjct: 548 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCL 605 Query: 77 GPDVKDLAALRVQLREQ---HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNV 133 + ++ +V L +L Q + VSR+ + P DIALL+L P + Sbjct: 606 EKSPRP-SSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVI 658 Query: 134 SSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH 193 + V LP + C++TGWG+ LK+ ++P++EN +C+ Sbjct: 659 TDKVIPACLPSPNYVVADRTECFITGWGETQ---GTFGAGLLKEAQLPVIENKVCNRYEF 715 Query: 194 LGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQP 251 L V+ LCAG DSCQGDSGGPLVC ++ GV SWG GCA+P Sbjct: 716 LNGR-------VQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARP 768 Query: 252 NRPGIYTRVTYYLDWIHHYVPKK 274 N+PG+Y RV+ ++ WI + Sbjct: 769 NKPGVYVRVSRFVTWIEGVMRNN 791 >3P8G-A nrPDB Length = 241 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 98/253 (38%), Positives = 129/253 (50%), Gaps = 24/253 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV--------KD 82 +VGG +A +WPWQVSL G H CG SLI P W+++AAHC D + Sbjct: 1 VVGGTDADEGEWPWQVSLHALG--QGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142 A L + + Q Q + RII HP F DIALLELE+P SS V + L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P AS FP G WVTGWG L++ ++ +++ C+ Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTG--ALILQKGEIRVIQQTTCE---------NLLP 167 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPL-VCKVNGTWLQAGVVSWGEGCAQPNRPGIYTR 259 + + M+C G + DSCQGDSGGPL + +G QAGVVSWG+GCAQ N+PG+YTR Sbjct: 168 QQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTR 227 Query: 260 VTYYLDWIHHYVP 272 + + DWI Sbjct: 228 LPLFRDWIKENTG 240 >1SGF-G nrPDB Length = 237 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 80/262 (30%), Positives = 121/262 (46%), Gaps = 42/262 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + ++ PW V++ Y + CGG L+ P WVLTAAHC + +V L Sbjct: 1 IVGGFKCEKNSQPWHVAVYR---YTQYLCGGVLLDPNWVLTAAHCYDDN------YKVWL 51 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTA-----------QIGADIALLELEEPVNVSSH 136 + +L Q VS+ I HP F + D+ LL L +P +++ Sbjct: 52 GKNNLFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDT 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V +TLP G C +GWG + + L V + ++ N C + Sbjct: 112 VKPITLPTEEPKL--GSTCLASGWGSI-TPTKFQFTDDLYCVNLKLLPNEDCAKAH---- 164 Query: 197 YTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNR 253 + V D MLCAG + +D+C+GDSGGPL+C + G+ SWG C +P+ Sbjct: 165 -----IEKVTDAMLCAGEMDGGKDTCKGDSGGPLICD----GVLQGITSWGHTPCGEPDM 215 Query: 254 PGIYTRVTYYLDWIHHYVPKKP 275 PG+YT++ + WI + K P Sbjct: 216 PGVYTKLNKFTSWIKDTMAKNP 237 >2OCV-B nrPDB Length = 259 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 90/266 (33%), Positives = 126/266 (47%), Gaps = 33/266 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 IV G +A + PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I VHP++ + DIALL+L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 142 LPPAS---ETFPPGMPCWVTGWGDVDNDERLP----PPFPLKQVKVPIMENHICDAKYHL 194 LP G VTGWG++ P L+ V +PI+E +C A Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKAS--- 176 Query: 195 GAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWGEG 247 + D+M CAG R D+C+GDSGGP V K N W Q G+VSWGEG Sbjct: 177 ------TRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG 230 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVPK 273 C + + G YT V WI + + Sbjct: 231 CDRKGKYGFYTHVFRLKAWIQKVIDQ 256 >1KIG-H nrPDB Length = 241 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 119/252 (47%), Gaps = 25/252 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++ + PWQ L FCGG++++ +VLTAAHC+ + V++ Sbjct: 1 IVGGRDCAEGECPWQALLV--NEENEGFCGGTILNEFYVLTAAHCLHQAKR----FTVRV 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP--- 144 +++ ++ V + H +F DIA+L L+ P+ +V LP Sbjct: 55 GDRNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDW 114 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A T V+G+G RL LK ++VP ++ C Sbjct: 115 AEATLMTQKTGIVSGFGRTHEKGRLSS--TLKMLEVPYVDRSTCKLSSSF---------T 163 Query: 205 VRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + +M CAG + D+CQGDSGGP V + T+ G+VSWGEGCA+ + G+YT+V+ Sbjct: 164 ITPNMFCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSN 223 Query: 263 YLDWIHHYVPKK 274 +L WI + + Sbjct: 224 FLKWIDKIMKAR 235 >1SC8-U nrPDB Length = 262 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 82/258 (31%), Positives = 124/258 (48%), Gaps = 20/258 (7%) Query: 28 RVGIVGGQEAPRSKWPWQVSLRVH--GPYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDL 83 R I+GG+ PW ++ G + CGGSLI P WV++A HC P +D Sbjct: 13 RFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDY 72 Query: 84 AALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG--ADIALLELEEP----VNVSSHV 137 + R + V +I+H + + DIALL++ S + Sbjct: 73 IVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTI 132 Query: 138 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 197 T++LP G C +TG+G ++ + L P LK V ++ + C ++ G+ Sbjct: 133 QTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQ-LKMTVVKLISHRECQQPHYYGSE 191 Query: 198 TGDDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPG 255 V MLCA + + DSCQGDSGGPLVC + G G+VSWG GCA ++PG Sbjct: 192 -------VTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPG 244 Query: 256 IYTRVTYYLDWIHHYVPK 273 +YTRV+++L WI + + Sbjct: 245 VYTRVSHFLPWIRSHTKE 262 >4NFE-A nrPDB Length = 237 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 92/262 (35%), Positives = 130/262 (49%), Gaps = 42/262 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQV++ HG W H CGG L+HPQWVLTAAHC+ + + V L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHG--WAH-CGGVLVHPQWVLTAAHCLKKNSQ------VWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSH 136 +L+ + Q +PVS HP + + + D+ LL L EP ++ Sbjct: 52 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 112 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRP-RSLQCVSLHLLSNDMCARAYS--- 165 Query: 197 YTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 253 V + MLCAG +D+C GDSGGPLVC + G+ SWG E CA P + Sbjct: 166 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEK 215 Query: 254 PGIYTRVTYYLDWIHHYVPKKP 275 P +YT+V +Y WI + P Sbjct: 216 PAVYTKVVHYRKWIKDTIAANP 237 >1VR1-H nrPDB Length = 261 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 87/269 (32%), Positives = 125/269 (46%), Gaps = 35/269 (13%) Query: 31 IVGGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD----- 82 IV G +A PWQV L P CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 83 ---LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVH 138 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 139 TVTLP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAK 191 V LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK-- 178 Query: 192 YHLGAYTGDDVRIVRDDMLCA-----GNTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSW 244 + D+M CA R D+C+GDSGGP V K N W Q G+VSW Sbjct: 179 -------DSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW 231 Query: 245 GEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GEGC + + G YT V WI + + Sbjct: 232 GEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 260 >1C5M-D nrPDB Length = 255 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 79/252 (31%), Positives = 122/252 (48%), Gaps = 25/252 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGGQE + PWQ L FCGG+++ ++LTAAHC+ + +V++ Sbjct: 1 IVGGQECKDGECPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKR----FKVRV 54 Query: 91 REQHLYYQDQ---LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP--- 144 +++ ++ + V +I H +F DIA+L L+ P+ +V LP Sbjct: 55 GDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDW 114 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A T V+G+G R LK ++VP ++ + C I Sbjct: 115 AESTLMTQKTGIVSGFGRTHEKGR--QSTRLKMLEVPYVDRNSCKLSSSF---------I 163 Query: 205 VRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + +M CAG + D+CQGDSGGP V + T+ G+VSWGEGCA+ + GIYT+VT Sbjct: 164 ITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTA 223 Query: 263 YLDWIHHYVPKK 274 +L WI + + Sbjct: 224 FLKWIDRSMKTR 235 >1ETT-H nrPDB Length = 259 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 89/266 (33%), Positives = 128/266 (48%), Gaps = 33/266 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I +HP++ + DIALL+L+ P+ +S ++H V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDVDNDERLP----PPFPLKQVKVPIMENHICDAKYHL 194 LP A++ G VTGWG+ P L+ V +P++E +C A Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAS--- 176 Query: 195 GAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCK--VNGTWLQAGVVSWGEG 247 + D+M CAG R D+C+GDSGGP V K N W Q G+VSWGEG Sbjct: 177 ------TRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG 230 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVPK 273 C + + G YT V WI + + Sbjct: 231 CDRDGKYGFYTHVFRLKKWIQKVIDR 256 >2V35-A nrPDB Length = 240 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 95/253 (37%), Positives = 139/253 (54%), Gaps = 22/253 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVH-GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG EA R+ WP Q+SL+ G W H CGG+LI WV+TAAHCV ++ RV Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDREL----TFRVV 56 Query: 90 LREQHLYY---QDQLLPVSRIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPP 144 + E +L +Q + V +I+VHP + T + G DIALL L + V ++S+V LP Sbjct: 57 VGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPR 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A PC++TGWG + +L L+Q +P ++ IC + + G+ Sbjct: 117 AGTILANNSPCYITGWGLTRTNGQL--AQTLQQAYLPTVDYAICSSSSYWGS-------T 167 Query: 205 VRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGE--GCAQPNRPGIYTRVT 261 V++ M+CAG R CQGDSGGPL C VNG + GV S+ GC +P ++TRV+ Sbjct: 168 VKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVS 227 Query: 262 YYLDWIHHYVPKK 274 Y+ WI++ + Sbjct: 228 AYISWINNVIASN 240 >2OQ5-A nrPDB Length = 232 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 93/245 (37%), Positives = 125/245 (51%), Gaps = 17/245 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E +WPWQ SL+ G H CG +LI+ W+++AAHC K+ A Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGS---HRCGATLINATWLVSAAHCFTT-YKNPARWTASF 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + + RIIVH ++ DI+L EL PV ++ VH V LP AS F Sbjct: 57 GVT-IKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQ 115 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PG +VTG+G + ND L+Q +V +++ C+ + ML Sbjct: 116 PGDVMFVTGFGALKNDG--YSQNHLRQAQVTLIDATTCNEPQAYN-------DAITPRML 166 Query: 211 CAG--NTRRDSCQGDSGGPLV-CKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG + D+CQGDSGGPLV W AG+VSWG+ CA+PN+PG+YTRVT DWI Sbjct: 167 CAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 226 Query: 268 HHYVP 272 Sbjct: 227 TSKTG 231 >2R0L-A nrPDB Length = 248 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 78/251 (31%), Positives = 123/251 (49%), Gaps = 21/251 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAALRV 88 I+GG + PW ++ + FC GSL+H WV++AAHC P ++ + Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQ-IGADIALLELEEP----VNVSSHVHTVTLP 143 Q Q + + I + + D+ L+ L++ S V + LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 TFP G C + GWG +D + L++ VP++ +H C + GA Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSS-SLREALVPLVADHKCSSPEVYGAD------ 169 Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 + +MLCAG + + D+CQGDSGGPL C+ NG G++SWG+GC + ++PG+YTRV Sbjct: 170 -ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVA 228 Query: 262 YYLDWIHHYVP 272 Y+DWI+ + Sbjct: 229 NYVDWINDRIR 239 >2EEK-A nrPDB Length = 220 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 85/247 (34%), Positives = 123/247 (49%), Gaps = 32/247 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + QVSL HFCGGSL+ WV++AAHC + LRV+L Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCYK------SVLRVRL 50 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 E H+ +Q + S +I HP + + I DI L++L +P ++ +VH V LP E Sbjct: 51 GEHHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--E 108 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 C V+GWG+ + + L+ + +PI+ + C Y ++ Sbjct: 109 CAADATMCTVSGWGNTMS--SVADGDKLQCLSLPILSHADCANSY---------PGMITQ 157 Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 M CAG +DSCQGDSGGP+VC + GVVSWG GCA+ + PG+Y +V Sbjct: 158 SMFCAGYLEGGKDSCQGDSGGPVVCN----GVLQGVVSWGYGCAERDHPGVYAKVCVLSG 213 Query: 266 WIHHYVP 272 W+ + Sbjct: 214 WVRDTMA 220 >3F6U-H nrPDB Length = 240 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 91/253 (35%), Positives = 129/253 (50%), Gaps = 27/253 (10%) Query: 32 VGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLR 91 + G+ R PWQV L CG LIHP WVLTAAHC+ K L V+L Sbjct: 2 IDGKMTRRGDSPWQVVLL--DSKKKLACGAVLIHPSWVLTAAHCMDESKK----LLVRLG 55 Query: 92 EQHLYYQDQL---LPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS-- 146 E L ++ L + + VHP + + DIALL L +P +S + + LP + Sbjct: 56 EYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLA 115 Query: 147 --ETFPPGMPCWVTGWGDVDNDER---LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDD 201 E G VTGWG + E+ F L +K+P++ ++ C Sbjct: 116 ERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMS-------- 167 Query: 202 VRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTR 259 +V ++MLCAG R+D+C+GDSGGP+V +GTW G+VSWGEGC + G+YT+ Sbjct: 168 -NMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTK 226 Query: 260 VTYYLDWIHHYVP 272 V+ YLDWIH ++ Sbjct: 227 VSRYLDWIHGHIR 239 >1FI8-A nrPDB Length = 228 Score = 247 bits (631), Expect = 3e-66, Method: Composition-based stats. Identities = 80/249 (32%), Positives = 126/249 (50%), Gaps = 28/249 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPY-WMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG EA P+ L++ Y CGG LI +VLTAAHC G ++V Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK------IQVT 54 Query: 90 LREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L ++ Q+ Q++PV +II HP + + I DI LL+L+ SS V + LP + Sbjct: 55 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 114 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 PG C+V GWG + + L++V++ + E+ C++ + Sbjct: 115 VKVKPGDVCYVAGWGKLGPMGK--YSDTLQEVELTVQEDQKCES--------YLKNYFDK 164 Query: 207 DDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 + +CAG+ +R S +GDSGGPLVCK + AG+VS+G+ + P +T+V+ +L Sbjct: 165 ANEICAGDPKIKRASFRGDSGGPLVCKK----VAAGIVSYGQN--DGSTPRAFTKVSTFL 218 Query: 265 DWIHHYVPK 273 WI + K Sbjct: 219 SWIKKTMKK 227 >4Z6A-H nrPDB Length = 249 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 86/253 (33%), Positives = 126/253 (49%), Gaps = 23/253 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ P+ + PWQV L V+G CGG+LI+ WV++AAHC + V L Sbjct: 1 IVGGKVCPKGECPWQVLLLVNG---AQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAV-L 56 Query: 91 REQHLYY---QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP--- 144 E L +Q V+++I+ + DIALL L +PV ++ HV + LP Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 + T V+GWG + +R L + VP + C+A Y Sbjct: 117 SERTLAFVRFSLVSGWGQLL--DRGATALELMVLNVPRLMTQDCEASY---------PGK 165 Query: 205 VRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTY 262 + + M CAG + +DSC+GDSGGP GTW G+VSWG+GCA G+YTRV+ Sbjct: 166 ITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQ 225 Query: 263 YLDWIHHYVPKKP 275 Y++W+ + +P Sbjct: 226 YIEWLQKLMRSEP 238 >5LHN-A nrPDB Length = 247 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 84/255 (32%), Positives = 125/255 (49%), Gaps = 21/255 (8%) Query: 31 IVGGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAA 85 IVGG+ PW ++ G CGGSLI P WV +AAHC P ++ Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQ--IGADIALLELEEP----VNVSSHVHT 139 Q +E + V ++I+H + DIALL++ S + T Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 199 + LPP P G C +TG+G + L P LK V ++ + C ++ G+ Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKN-LKMSVVKLVSHEQCMQPHYYGSE-- 177 Query: 200 DDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIY 257 + MLCA + + DSC+GDSGGPL+C + G +G+VSWG GCA+ N+PG+Y Sbjct: 178 -----INYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVY 232 Query: 258 TRVTYYLDWIHHYVP 272 TRV+++LDWI ++ Sbjct: 233 TRVSHFLDWIQSHIG 247 >1A5I-A nrPDB Length = 265 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 81/256 (31%), Positives = 116/256 (45%), Gaps = 25/256 (9%) Query: 33 GGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV--KDLAALR 87 GG + PWQ ++ CGG LI WVLTAAHC L + Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELE----EPVNVSSHVHTVTLP 143 + ++Q V + IVH +F DIALL+L+ + S V + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 A+ P C ++G+G + LK+ V + + C K+ + Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFY-SEQLKEGHVRLYPSSRCAPKFLFN-------K 187 Query: 204 IVRDDMLCAGNTRR--------DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPG 255 V ++MLCAG+TR D+CQGDSGGPLVC + G++SWG GC + + PG Sbjct: 188 TVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPG 247 Query: 256 IYTRVTYYLDWIHHYV 271 +YT+VT YL WI + Sbjct: 248 VYTKVTNYLGWIRDNM 263 >1SPJ-A nrPDB Length = 238 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 84/263 (31%), Positives = 114/263 (43%), Gaps = 43/263 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQ +L + CGG L+H QWVLTAAHC+ + ++ L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ---CGGILVHRQWVLTAAHCISDN------YQLWL 51 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFY-----------TAQIGADIALLELEEPV-NVSS 135 +L Q + VS HP F D+ LL L EP ++ Sbjct: 52 GRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITD 111 Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195 V V LP G C +GWG ++ E P L+ V + I+ N C + Sbjct: 112 AVKVVELPTEEPEV--GSTCLASGWGSIEP-ENFSFPDDLQCVDLKILPNDECKKAH--- 165 Query: 196 AYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPN 252 V+ V D MLC G +D+C GDSGGPL+C + GV SWG C PN Sbjct: 166 ------VQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCD----GVLQGVTSWGYVPCGTPN 215 Query: 253 RPGIYTRVTYYLDWIHHYVPKKP 275 +P + RV Y+ WI + + Sbjct: 216 KPSVAVRVLSYVKWIEDTIAENS 238 >1FIZ-A nrPDB Length = 263 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 83/260 (31%), Positives = 123/260 (47%), Gaps = 25/260 (9%) Query: 31 IVGGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 +VGG A WPW VSL+ H H CGG L++ WVLTAAHC + K + R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFK-NKKKVTDWR 59 Query: 88 VQLREQHLYYQD--------QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHT 139 + + + Q V II+H ++ + DIAL+++ PV + Sbjct: 60 LIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGP 119 Query: 140 VTLPPASETFPPG-MPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYT 198 LP P CWVTGWG + P L++ +V +++ +C++ Sbjct: 120 GCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSP-TLQEARVALIDLELCNSTRWYNGR- 177 Query: 199 GDDVRIVRDDMLCAGN--TRRDSCQGDSGGPLVCKVN--GTWLQAGVVSWGEGCAQPNRP 254 +R +CAG + D+CQGDSGGPL+C+ T++ G+ SWG GCA+ RP Sbjct: 178 ------IRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRP 231 Query: 255 GIYTRVTYYLDWIHHYVPKK 274 G+YT YL+WI + Sbjct: 232 GVYTSTWPYLNWIASKIGSN 251 >1ELT-A nrPDB Length = 236 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 88/249 (35%), Positives = 134/249 (53%), Gaps = 21/249 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVH-GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 +VGG+ A + WPWQ+SL+ G + H CGGSLI WV+TAAHCV RV Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS----ARTWRVV 56 Query: 90 LREQHL---YYQDQLLPVSRIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPP 144 L E +L ++Q++ V+ + +H + + + G DIALL L +++S V LPP Sbjct: 57 LGEHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPP 116 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 +++ P PC++TGWG P LKQ +P +++ C + G+ Sbjct: 117 SNQILPNNNPCYITGWGKTSTGG--PLSDSLKQAWLPSVDHATCSSSGWWGS-------T 167 Query: 205 VRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVTY 262 V+ M+CAG C GDSGGPL C+VNG++ GV S+ GC +P ++TRV+ Sbjct: 168 VKTTMVCAGGGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSA 227 Query: 263 YLDWIHHYV 271 Y+ W++ + Sbjct: 228 YISWMNGIM 236 >5MS3-A nrPDB Length = 228 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 84/252 (33%), Positives = 120/252 (47%), Gaps = 33/252 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E PWQ +L CGG L+ WVLTAAHC P V+L Sbjct: 1 VLGGHECQPHSQPWQAALF---QGQQLLCGGVLVGGNWVLTAAHCKKPK------YTVRL 51 Query: 91 REQHLYYQ---DQLLPVSRIIVHPQFYT---AQIGADIALLELEEPVNVSSHVHTVTLPP 144 + L + +Q +PV + I HP + + D+ LL+L + ++ S V ++L Sbjct: 52 GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL-- 109 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A PG C V+GWG V + R P L +V I C+ Y Sbjct: 110 ADHCTQPGQKCTVSGWGTVTSP-RENFPDTLNCAEVKIFPQKKCEDAY---------PGQ 159 Query: 205 VRDDMLCAGNTRR-DSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTY 262 + D M+CAG+++ D+CQGDSGGPLVC G+ SWG C + ++PG+YT + Sbjct: 160 ITDGMVCAGSSKGADTCQGDSGGPLVCD----GALQGITSWGSDPCGRSDKPGVYTNICR 215 Query: 263 YLDWIHHYVPKK 274 YLDWI + K Sbjct: 216 YLDWIKKIIGSK 227 >1FIW-A nrPDB Length = 290 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 85/259 (32%), Positives = 129/259 (49%), Gaps = 25/259 (9%) Query: 31 IVGGQEAPRSKWPWQVSLR---VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 I+GGQ+A WPW VSL+ H H CGGSL++ QW+LTAAHC K + R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKK-VTDWR 59 Query: 88 VQLREQHLYYQD--------QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHT 139 + + + + Q V +II+H ++ + DIAL+++ PV + Sbjct: 60 LIFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGP 119 Query: 140 VTLPPASETFPPG-MPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYT 198 LP P CWV GWG + + R P L++ +V +++ +C++ Sbjct: 120 GCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPM-LQEARVDLIDLGLCNSTRWYNGR- 177 Query: 199 GDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWGEGCAQPNRP 254 +R +CAG + D+CQGDSGGPL+CK +++ G+ SWG GCA+ RP Sbjct: 178 ------IRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRP 231 Query: 255 GIYTRVTYYLDWIHHYVPK 273 G+YT YL+WI + Sbjct: 232 GVYTSTWSYLNWIASKIGS 250 >3BSQ-A nrPDB Length = 227 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 83/246 (33%), Positives = 117/246 (47%), Gaps = 29/246 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G R PWQV+L CGG L++ +WVLTAAHC + V L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLH---CGGVLVNERWVLTAAHC------KMNEYTVHL 51 Query: 91 REQHL-YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 L + Q + S+ HP + T D+ L++L +SS V V LP E Sbjct: 52 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 109 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PPG C V+GWG + + P L V V ++ C Y ++ + M Sbjct: 110 PPGTTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDCTKVYK---------DLLENSM 159 Query: 210 LCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLDW 266 LCAG ++++++C GDSGGPLVC G+VSWG C QPN PG+YT+V + W Sbjct: 160 LCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKW 215 Query: 267 IHHYVP 272 I+ + Sbjct: 216 INDTMK 221 >1IAU-A nrPDB Length = 227 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 113/248 (45%), Gaps = 27/248 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG EA P+ L + + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q+ Q +PV R I HP + DI LL+LE + V + LP Sbjct: 55 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG + L++VK+ + E+ C++ + + Sbjct: 115 QVKPGQTCSVAGWGQTAPLGKH--SHTLQEVKMTVQEDRKCESDLRHYYDSTIE------ 166 Query: 208 DMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 LC G+ ++ S +GDSGGPLVC + G+VS+G P P T+V+ ++ Sbjct: 167 --LCVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVH 218 Query: 266 WIHHYVPK 273 WI + + Sbjct: 219 WIKKTMKR 226 >1ELV-A nrPDB Length = 333 Score = 241 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 74/273 (27%), Positives = 117/273 (42%), Gaps = 28/273 (10%) Query: 17 YAAP-APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC 75 P P + QR I+GG +A +PWQV + GG+LI+ WVLTAAH Sbjct: 70 CGVPREPFEEKQR--IIGGSDADIKNFPWQVFFDN------PWAGGALINEYWVLTAAHV 121 Query: 76 VGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-------TAQIGADIALLELE 128 V + + + + + ++L + +HP + DIAL+ L+ Sbjct: 122 VEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLK 181 Query: 129 EPVNVSSHVHTVTLP--PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENH 186 +PV + V + LP + G ++GWG + +R LK ++P+ Sbjct: 182 DPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR---AVRLKAARLPVAPLR 238 Query: 187 ICDAKYHLGAYTGDDVRIVRDDMLCAGNTRR-DSCQGDSGGPLVCKVNG---TWLQAGVV 242 C + + +M+CAG + DSC+GDSGG + + AG+V Sbjct: 239 KCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLV 298 Query: 243 SWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275 SWG C G+YTRV Y+DWI + + Sbjct: 299 SWGPQCGT---YGLYTRVKNYVDWIMKTMQENS 328 >5UBM-A nrPDB Length = 252 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 25/259 (9%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG +A +PWQV + GG+LI+ WVLTAAH V + + + Sbjct: 1 RIIGGSDADIKNFPWQVFFDN------PWAGGALINEYWVLTAAHVVEGNREPTMYVGST 54 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFY-------TAQIGADIALLELEEPVNVSSHVHTVTL 142 + + ++L + +HP + DIAL+ L++PV + V + L Sbjct: 55 SVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICL 114 Query: 143 P--PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200 P + G ++GWG + +R LK ++P+ C Sbjct: 115 PGTSSDYNLMDGDLGLISGWGRTEKRDR---AVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 201 DVRIVRDDMLCAGNTRR-DSCQGDSGGPLVCKVNG---TWLQAGVVSWGEGCAQPNRPGI 256 + + +M+CAG + DSC+GDSGG + + AG+VSWG C G+ Sbjct: 172 EAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT---YGL 228 Query: 257 YTRVTYYLDWIHHYVPKKP 275 YTRV Y+DWI + + Sbjct: 229 YTRVKNYVDWIMKTMQENS 247 >3QUM-P nrPDB Length = 237 Score = 239 bits (611), Expect = 7e-64, Method: Composition-based stats. Identities = 84/260 (32%), Positives = 120/260 (46%), Gaps = 38/260 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG E + PWQV + G CGG L+HPQWVLTAAHC+ ++ + + + Sbjct: 1 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCI----RNKSVILLGR 53 Query: 91 REQ-HLYYQDQLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSHVH 138 H Q+ VS HP + + + D+ LL L EP ++ V Sbjct: 54 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 113 Query: 139 TVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYT 198 + LP G C+ +GWG ++ E P L+ V + ++ N +C + Sbjct: 114 VMDLPTQEPAL--GTTCYASGWGSIEP-EEFLTPKKLQCVDLHVISNDVCAQVH------ 164 Query: 199 GDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPG 255 + V MLCAG + +C GDSGGPLVC + G+ SWG E CA P RP Sbjct: 165 ---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPS 217 Query: 256 IYTRVTYYLDWIHHYVPKKP 275 +YT+V +Y WI + P Sbjct: 218 LYTKVVHYRKWIKDTIVANP 237 >5TO3-B nrPDB Length = 409 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 86/266 (32%), Positives = 125/266 (46%), Gaps = 33/266 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDVDN----DERLPPPFPLKQVKVPIMENHICDAKYHL 194 LP A+ G VTGWG++ + P L+ V +PI+E +C Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK----- 174 Query: 195 GAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSGGPLVCKV--NGTWLQAGVVSWGEG 247 + D+M CAG R D+C+GDSGGP V K N W Q G+VS G G Sbjct: 175 ----DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAG 230 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVPK 273 C + + G YT V WI + + Sbjct: 231 CDRDGKYGFYTHVFRLKKWIQKVIDQ 256 >1NPM-A nrPDB Length = 225 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 77/250 (30%), Positives = 114/250 (45%), Gaps = 33/250 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G+E PWQ +L CGG L+ +WVLTAAHC V+L Sbjct: 1 ILEGRECIPHSQPWQAALF---QGERLICGGVLVGDRWVLTAAHCKKQK------YSVRL 51 Query: 91 REQHLYY---QDQLLPVSRIIVHPQF---YTAQIGADIALLELEEPVNVSSHVHTVTLPP 144 + L +Q + V++ I HP + DI L+ L+ N+ V V L Sbjct: 52 GDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL-- 109 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 A+ G C ++GWG V + + P L +V I + C+ Y Sbjct: 110 ANLCPKVGQKCIISGWGTVTSPQE-NFPNTLNCAEVKIYSQNKCERAY---------PGK 159 Query: 205 VRDDMLCAGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTY 262 + + M+CAG++ D+CQGDSGGPLVC + G+ SWG C +P +PG+YT++ Sbjct: 160 ITEGMVCAGSSNGADTCQGDSGGPLVCD----GMLQGITSWGSDPCGKPEKPGVYTKICR 215 Query: 263 YLDWIHHYVP 272 Y WI + Sbjct: 216 YTTWIKKTMD 225 >2PSX-A nrPDB Length = 227 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 116/251 (46%), Gaps = 30/251 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G + PWQ +L + +CG L+HPQW+LTAAHC RV+L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPN--QLYCGAVLVHPQWLLTAAHC------RKKVFRVRL 52 Query: 91 REQHLYY----QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L Q+ + I HP + D+ L++L + + V + + +S Sbjct: 53 GHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV--SS 110 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 G C V+GWG + + + P L+ + + ++ C+ Y R + Sbjct: 111 HCPSAGTKCLVSGWGTTKSPQ-VHFPKVLQCLNISVLSQKRCEDAY---------PRQID 160 Query: 207 DDMLCAGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 264 D M CAG+ RDSCQGDSGGP+VC G+VSWG+ CA+PNRPG+YT + + Sbjct: 161 DTMFCAGDKAGRDSCQGDSGGPVVCN----GSLQGLVSWGDYPCARPNRPGVYTNLCKFT 216 Query: 265 DWIHHYVPKKP 275 WI + Sbjct: 217 KWIQETIQANS 227 >5ZFH-A nrPDB Length = 224 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 84/246 (34%), Positives = 116/246 (47%), Gaps = 29/246 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G + PWQV+L CGG L+ WVLTAAHC + +VQL Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLH---CGGVLVDKYWVLTAAHC------KMGQYQVQL 51 Query: 91 REQHL-YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + Q + ++ HP + T DI L+ L+EPV +SS V V LP E Sbjct: 52 GSDKIGDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE-- 109 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PPG C V+GWG + + P L V ++ + C Y ++ M Sbjct: 110 PPGTSCTVSGWGTTTSPDVTFPSD-LMCSDVKLISSRECKKVYK---------DLLGKTM 159 Query: 210 LCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLDW 266 LCAG +++ ++C GDSGGPLVC G+VSWG C QPN PG+YT+V Y W Sbjct: 160 LCAGIPDSKTNTCNGDSGGPLVCND----TLQGLVSWGTYPCGQPNDPGVYTQVCKYKRW 215 Query: 267 IHHYVP 272 + + Sbjct: 216 VMETMK 221 >1Q3X-A nrPDB Length = 328 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 79/265 (29%), Positives = 120/265 (45%), Gaps = 22/265 (8%) Query: 19 APAPGQALQRV--GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 P G + + I GGQ+A +PWQV + G+L++ WVLTAAH V Sbjct: 73 EPVCGLSARTTGGRIYGGQKAKPGDFPWQVLI-----LGGTTAAGALLYDNWVLTAAHAV 127 Query: 77 GPDVKDLAALRVQLREQHLYYQDQLLPVSR-IIVHPQF-YTAQIGADIALLELEEPVNVS 134 D +AL +++ S + +H + + A DIAL++L V ++ Sbjct: 128 YEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVIN 187 Query: 135 SHVHTVTLP--PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192 S++ + LP A +GWG R L V +PI+++ C A Y Sbjct: 188 SNITPICLPRKEAESFMRTDDIGTASGWGLTQ---RGFLARNLMYVDIPIVDHQKCTAAY 244 Query: 193 HLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVN--GTWLQAGVVSWGE-G 247 Y V +MLCAG + +DSC+GDSGG LV + W G+VSWG Sbjct: 245 EKPPYPRGS---VTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 301 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVP 272 C + + G+YT+V Y+ WI + + Sbjct: 302 CGEAGQYGVYTKVINYIPWIENIIS 326 >1NN6-A nrPDB Length = 228 Score = 236 bits (602), Expect = 9e-63, Method: Composition-based stats. Identities = 77/250 (30%), Positives = 118/250 (47%), Gaps = 30/250 (12%) Query: 31 IVGGQEAPRSKWPWQVSL-RVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E P+ L V FCGG LI +VLTAAHC G + V Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS------ITVT 56 Query: 90 LREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L ++ ++ Q L V + HP++ T+ + DI LL+L+E +++ V T+ P Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 PPG C V GWG + P L++VK+ +M+ C Sbjct: 117 NFVPPGRMCRVAGWGRTGVLK--PGSDTLQEVKLRLMDPQACS----------HFRDFDH 164 Query: 207 DDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 + LC GN R + + +GDSGGPL+C + G+VS+G A+P P ++TR+++Y Sbjct: 165 NLQLCVGNPRKTKSAFKGDSGGPLLC----AGVAQGIVSYGRSDAKP--PAVFTRISHYR 218 Query: 265 DWIHHYVPKK 274 WI+ + Sbjct: 219 PWINQILQAN 228 >6QHB-A nrPDB Length = 223 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 80/249 (32%), Positives = 115/249 (46%), Gaps = 33/249 (13%) Query: 32 VGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLR 91 V G ++ P+Q +L G CGG LIHP WVLTAAHC P+ L+V L Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHL---LCGGVLIHPLWVLTAAHCKKPN------LQVFLG 52 Query: 92 EQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + +L + V R ++HP + A DI LL L P +S + LP + Sbjct: 53 KHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDC 110 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 C + GWG + + P ++ + ++ C+ Y + + Sbjct: 111 SAQTTSCHILGWGKTADGD---FPDTIQCAYIHLVSREECEHAY---------PGQITQN 158 Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLD 265 MLCAG+ + +DSCQGDSGGPLVC + G+VSWG C +PG+YT V Y + Sbjct: 159 MLCAGDEKYGKDSCQGDSGGPLVCGDH----LRGLVSWGNIPCGSKEKPGVYTNVCRYTN 214 Query: 266 WIHHYVPKK 274 WI + K Sbjct: 215 WIQKTIQAK 223 >3TK9-A nrPDB Length = 226 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 72/248 (29%), Positives = 116/248 (46%), Gaps = 28/248 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG EA P+ ++ CGG L+ +VLTAAHC G +++ V L Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQG------SSINVTL 54 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q+ Q +PV R I HP + +I LL+LE ++ V + LP + Sbjct: 55 GAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKA 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG V L++V + + ++ C+ +H R Sbjct: 115 QVKPGQLCSVAGWGYVSMST---LATTLQEVLLTVQKDCQCERLFHGNYS--------RA 163 Query: 208 DMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +C G+ ++ +GDSGGPLVCK + G++S+G P PG+Y +V+++L Sbjct: 164 TEICVGDPKKTQTGFKGDSGGPLVCKD----VAQGILSYGNKKGTP--PGVYIKVSHFLP 217 Query: 266 WIHHYVPK 273 WI + + Sbjct: 218 WIKRTMKR 225 >4J1Y-A nrPDB Length = 397 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 72/273 (26%), Positives = 115/273 (42%), Gaps = 28/273 (10%) Query: 17 YAAP-APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC 75 P P + R +GG +A +PWQV + GG+LI+ WVLTAAH Sbjct: 134 CGVPREPFEEKARA--IGGSDADIKNFPWQVFFDN------PWAGGALINEYWVLTAAHV 185 Query: 76 VGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-------TAQIGADIALLELE 128 V + + + + + ++L + +HP + DIAL+ L+ Sbjct: 186 VEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLK 245 Query: 129 EPVNVSSHVHTVTLP--PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENH 186 +PV + V + LP + G ++GWG + +R LK ++P+ Sbjct: 246 DPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR---AVRLKAARLPVAPLR 302 Query: 187 ICDAKYHLGAYTGDDVRIVRDDMLCAGNTRR-DSCQGDSGGPLVCKVNG---TWLQAGVV 242 C + + +M+CAG + DSC+GDSGG + + AG+V Sbjct: 303 KCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLV 362 Query: 243 SWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275 SWG C G+YTRV Y+DWI + + Sbjct: 363 SWGPQCGT---YGLYTRVKNYVDWIMKTMQENS 392 >1FDP-A nrPDB Length = 235 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 83/249 (33%), Positives = 120/249 (48%), Gaps = 22/249 (8%) Query: 28 RVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 R I+GG+EA P+ S++++G H CGG L+ QWVL+AAHC+ ++ Sbjct: 5 RGRILGGREAEAHARPYMASVQLNG---AHLCGGVLVAEQWVLSAAHCLEDAAD--GKVQ 59 Query: 88 VQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144 V L L + +L V R + HP I D+ LL+L E + V + Sbjct: 60 VLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQR 119 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 PG C V GWG V++ R P L+ V +P+++ C+ + H Sbjct: 120 VDRDVAPGTLCDVAGWGIVNHAGRRPDS--LQHVLLPVLDRATCNRRTHHD-------GA 170 Query: 205 VRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVV-SWGEGCAQPNRPGIYTRVTYY 263 + + ++CA + RRDSC+GDSGGPLVC + GVV S C +PGIYTRV Y Sbjct: 171 ITERLMCAESNRRDSCKGDSGGPLVC----GGVLEGVVTSGSRVCGNRKKPGIYTRVASY 226 Query: 264 LDWIHHYVP 272 WI + Sbjct: 227 AAWIDSVLA 235 >1ZJK-A nrPDB Length = 403 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 80/265 (30%), Positives = 121/265 (45%), Gaps = 22/265 (8%) Query: 19 APAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 P G + + G I GGQ+A +PWQV + G+L++ WVLTAAH V Sbjct: 148 EPVCGLSARTTGGQIYGGQKAKPGDFPWQVLI-----LGGTTAAGALLYDNWVLTAAHAV 202 Query: 77 GPDVKDLAALRVQLREQHLYYQDQLLPVSR-IIVHPQF-YTAQIGADIALLELEEPVNVS 134 D +AL +++ S + +H + + A DIAL++L V ++ Sbjct: 203 YEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVIN 262 Query: 135 SHVHTVTLP--PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192 S++ + LP A +GWG R L V +PI+++ C A Y Sbjct: 263 SNITPICLPRKEAESFMRTDDIGTASGWGLTQ---RGFLARNLMYVDIPIVDHQKCTAAY 319 Query: 193 HLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVN--GTWLQAGVVSWGE-G 247 Y V +MLCAG + +DSC+GDSGG LV + W G+VSWG Sbjct: 320 EKPPYPRGS---VTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 376 Query: 248 CAQPNRPGIYTRVTYYLDWIHHYVP 272 C + + G+YT+V Y+ WI + + Sbjct: 377 CGEAGQYGVYTKVINYIPWIENIIS 401 >4XDE-A nrPDB Length = 257 Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 90/253 (35%), Positives = 117/253 (46%), Gaps = 24/253 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG--PDVKDLAALRV 88 +VGG A R P+ +L FC GSLI P WVLTAAHC+ P +DL + Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS----FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVN-----VSSHVHTVTLP 143 Q R H Q L V +H F D+ALL L+E + +S +V V+LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 144 PASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203 + C V GWG F L++ +VP + C A G+ Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASF-LQEAQVPFLSLERCSAPDVHGSS------ 171 Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG---TWLQAGVVSWGEGCAQPNRPGIYT 258 + MLCAG D+CQGDSGGPLVC+ G++SWG GC N+PG+YT Sbjct: 172 -ILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYT 230 Query: 259 RVTYYLDWIHHYV 271 V YYL WI + Sbjct: 231 DVAYYLAWIREHT 243 >1FON-A nrPDB Length = 240 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 81/250 (32%), Positives = 123/250 (49%), Gaps = 18/250 (7%) Query: 33 GGQEAPRSKWPWQVSLRV-HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLR 91 G++A W WQVSL+ + H CGGSLI P WV+TA HC+ + + + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS-RTYQVVLGEYD 59 Query: 92 EQHLYYQDQLLPVS--RIIVHPQFYTAQI--GADIALLELEEPVNVSSHVHTVTLPPASE 147 L +Q++P++ + VHP + + + G DIAL++L + V LPPA + Sbjct: 60 RSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P PC+++GWG + P P L+Q +P ++ C G V+ Sbjct: 120 ILPNEAPCYISGWGRLYTGG--PLPDKLQQALLPTVDYEHCSQWDWWG-------ITVKK 170 Query: 208 DMLCAGNTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGE--GCAQPNRPGIYTRVTYYL 264 M+CAG R C GDSGGPL C +G+W GV S+ GC +P ++TRV+ ++ Sbjct: 171 TMVCAGGDTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFI 230 Query: 265 DWIHHYVPKK 274 DWI + Sbjct: 231 DWIDETIASN 240 >4KKD-A nrPDB Length = 433 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 79/285 (27%), Positives = 121/285 (42%), Gaps = 33/285 (11%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHG----PYWMHFCGGSLIHPQWVLTA 72 P+ I+GG+ A +PWQ + V P F G+L+ W+LTA Sbjct: 141 CGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTA 200 Query: 73 AHCVGPDVKDLAALRV---------QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIA 123 AH + +D + V L + +R+++HP F DIA Sbjct: 201 AHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIA 260 Query: 124 LLELEEPVNVSSHVHTVTLPPASETFP-PGMPCWVTGWG---------DVDNDERLPPPF 173 L++L+EPV + HV V LP P P M V GWG ++ + Sbjct: 261 LVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSD 320 Query: 174 PLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCK 231 L+ VK+P++ + C Y + V ++M CAG +D+C GDSG V Sbjct: 321 VLQYVKLPVVPHAECKTSYE----SRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIF 376 Query: 232 VN--GTWLQAGVVSWG--EGCAQPNRPGIYTRVTYYLDWIHHYVP 272 + W+ G+VSWG E C G+YT+V+ Y+DW+ + Sbjct: 377 DDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 421 >5FCR-A nrPDB Length = 234 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 84/248 (33%), Positives = 125/248 (50%), Gaps = 21/248 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GGQEA P+ S++V+G H CGG+L+ QWVL+AAHC+ V D +++V L Sbjct: 1 ILGGQEAAAHARPYMASVQVNG---THVCGGTLLDEQWVLSAAHCMDG-VTDDDSVQVLL 56 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + + V ++ HP + D+ L +L + ++ HV + L + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG V + R P L Q++V IM C+ + + +V Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRP--DVLHQLRVSIMNRTTCNLRTYHD-------GVVTI 167 Query: 208 DMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDW 266 +M+CA + RRD+C+GDSG PLVC GVV+WG C +PG+YTRV+ Y W Sbjct: 168 NMMCAESNRRDTCRGDSGSPLVCGD----AVEGVVTWGSRVCGNGKKPGVYTRVSSYRMW 223 Query: 267 IHHYVPKK 274 I + Sbjct: 224 IENITNGN 231 >1AO5-A nrPDB Length = 237 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 78/261 (29%), Positives = 115/261 (44%), Gaps = 42/261 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG ++ PWQV++ H CGG L+ WVLTAAHC V L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCYVDQ------YEVWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVNVSSH 136 + L+ ++ Q VS+ HP F + + D+ LL L +P +++ Sbjct: 52 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDV 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V + LP PG C +GWG + R P L+ V + ++ N C Y Sbjct: 112 VKPIALPTKE--PKPGSKCLASGWGSI-TPTRWQKPDDLQCVFITLLPNENCAKVY---- 164 Query: 197 YTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNR 253 ++ V D MLCAG +D+C+ DSGGPL+C + G S+G C +P Sbjct: 165 -----LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGV 215 Query: 254 PGIYTRVTYYLDWIHHYVPKK 274 P IYT + + WI + K Sbjct: 216 PAIYTNLIKFNSWIKDTMMKN 236 >3G01-A nrPDB Length = 227 Score = 232 bits (593), Expect = 8e-62, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 116/248 (46%), Gaps = 28/248 (11%) Query: 31 IVGGQEAPRSKWPWQVSL-RVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E P+ + FCGG L+ ++VLTAAHC G + V Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMT------VT 54 Query: 90 LREQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L ++ Q++PV++ I HP + DI LL+L + V + LP + Sbjct: 55 LGAHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRN 114 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 PG C+V GWG V D P L +VK+ + ++ +C++++ R Sbjct: 115 AHVKPGDECYVAGWGKVTPDGEFPK--TLHEVKLTVQKDQVCESQFQSSYN--------R 164 Query: 207 DDMLCAGNTRRD--SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 + +C G+++ S +GDSGGPLVCK AG+VS+G+ P ++TRV ++ Sbjct: 165 ANEICVGDSKIKGASFRGDSGGPLVCKR----AAAGIVSYGQTDGSA--PQVFTRVLSFV 218 Query: 265 DWIHHYVP 272 WI + Sbjct: 219 SWIKKTMK 226 >4FXG-H nrPDB Length = 242 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 116/251 (46%), Gaps = 20/251 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I GGQ+A +PWQV + G+L++ WVLTAAH V D +AL +++ Sbjct: 1 IYGGQKAKPGDFPWQVLI-----LGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 91 REQHLYYQDQLLPVSR-IIVHPQF-YTAQIGADIALLELEEPVNVSSHVHTVTLP--PAS 146 S + +H + + A DIAL++L V ++S++ + LP A Sbjct: 56 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 115 Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 +GWG R L V +PI+++ C A Y Y V Sbjct: 116 SFMRTDDIGTASGWGLTQ---RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGS---VT 169 Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCKVN--GTWLQAGVVSWGE-GCAQPNRPGIYTRVT 261 +MLCAG + +DSC+GD+GG LV + W G+VSWG C + + G+YT+V Sbjct: 170 ANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVI 229 Query: 262 YYLDWIHHYVP 272 Y+ WI + + Sbjct: 230 NYIPWIENIIS 240 >2XRC-A nrPDB Length = 565 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 85/257 (33%), Positives = 121/257 (47%), Gaps = 25/257 (9%) Query: 26 LQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAA 85 ++R IVGG+ A PWQV+++ CGG I W+LTAAHC+ Sbjct: 317 IRRKRIVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHCLRASKTHRYQ 373 Query: 86 L--RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHV----HT 139 + V + + V RII H + DIAL+E+++ N Sbjct: 374 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 433 Query: 140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 199 +P + F P C V+GWG ++ER+ F L+ +V ++ N C Y Sbjct: 434 ACVPWSPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN--CSKFY------- 481 Query: 200 DDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRPGI 256 R +M CAG + D+C+GDSGGPLVC N GVVSWGE C +P PG+ Sbjct: 482 -GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 540 Query: 257 YTRVTYYLDWIHHYVPK 273 YT+V Y DWI ++V + Sbjct: 541 YTKVANYFDWISYHVGR 557 >2B9L-A nrPDB Length = 394 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 122/254 (48%), Gaps = 17/254 (6%) Query: 35 QEAPRSKWPWQVSLRV-----HGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 EA ++PW V++ CGGSLI P VLT AHCV +L A++++ Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 90 LREQHLYYQDQLLP-----VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144 E + + LP + ++I+H F + D+ALL L+ P+ + ++ T+ LP Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 S+ F C+ +GWG + R LK++++P ++ C A L + Sbjct: 255 QSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQAD--LRNTRLGLKFV 311 Query: 205 VRDDMLCAGNT-RRDSCQGDSGGPLVCKVN---GTWLQAGVVSWGEGCAQPNRPGIYTRV 260 + +CAG +D+C GD G PL C ++Q G+V+WG GC N PG+Y V Sbjct: 312 LDQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANV 371 Query: 261 TYYLDWIHHYVPKK 274 ++ +WI + K Sbjct: 372 AHFRNWIDQEMQAK 385 >1TON-A nrPDB Length = 235 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 77/262 (29%), Positives = 114/262 (43%), Gaps = 44/262 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG + ++ PWQV++ + CGG LI P WV+TAAHC + +V L Sbjct: 1 IVGGYKCEKNSQPWQVAVINE-----YLCGGVLIDPSWVITAAHCYSNN------YQVLL 49 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYT-----------AQIGADIALLELEEPVNVSSH 136 +L+ + Q V + HP + D+ LL L EP +++ Sbjct: 50 GRNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGG 109 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V + LP G C +GWG + E + L+ V + ++ N C Y Sbjct: 110 VKVIDLPTKEPKV--GSTCLASGWGSTNPSEMV-VSHDLQCVNIHLLSNEKCIETYKDN- 165 Query: 197 YTGDDVRIVRDDMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNR 253 V D MLCAG +D+C GDSGGPL+C + G+ S G CA+P Sbjct: 166 --------VTDVMLCAGEMEGGKDTCAGDSGGPLICD----GVLQGITSGGATPCAKPKT 213 Query: 254 PGIYTRVTYYLDWIHHYVPKKP 275 P IY ++ + WI + + P Sbjct: 214 PAIYAKLIKFTSWIKKVMKENP 235 >6BQM-A nrPDB Length = 506 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 76/242 (31%), Positives = 121/242 (50%), Gaps = 5/242 (2%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG++A +WP+ V+L + FCGGS + ++VLTAAHCV + + + Sbjct: 10 RIIGGEQATAGEWPYMVALTARNSSHV-FCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLG 68 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + + + + V +I VH + TA +G DIA+LELE V ++ Sbjct: 69 AFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSSDFNEL 127 Query: 150 PPGMPCWVTGWGDVDN--DERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P V G+G+ E+ P L QV+VP + C K ++ + + Sbjct: 128 TKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTK-GSDQDAKNNYSQLTN 186 Query: 208 DMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 + CAG+ +D+C GD+GGP+ N Q GVVSWG+GC + N PG+YT ++ + DW+ Sbjct: 187 NAFCAGSFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSVFNDWL 246 Query: 268 HH 269 Sbjct: 247 DD 248 >4IW4-E nrPDB Length = 279 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 79/271 (29%), Positives = 120/271 (44%), Gaps = 33/271 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHG----PYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAAL 86 I+GG+ A +PWQ + V P F G+L+ W+LTAAH + +D + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 87 RV---------QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHV 137 V L + +R+++HP F DIAL++L+EPV + HV Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 138 HTVTLPPASETFP-PGMPCWVTGWG---------DVDNDERLPPPFPLKQVKVPIMENHI 187 V LP P P M V GWG ++ + L+ VK+P++ + Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVN--GTWLQAGVVS 243 C Y + V ++M CAG +D+C GDSGG V + W+ G+VS Sbjct: 181 CKTSYE----SRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVS 236 Query: 244 WG--EGCAQPNRPGIYTRVTYYLDWIHHYVP 272 WG E C G+YT+V+ Y+DW+ + Sbjct: 237 WGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 267 >1YM0-A nrPDB Length = 238 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 88/251 (35%), Positives = 126/251 (50%), Gaps = 20/251 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG EA ++PWQVS+R HFCGGS+I+ +WV+ AAHC+ + L +L V Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSD-SHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGE 59 Query: 91 REQHLYYQ-DQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP-PASET 148 + Q V I V+ + A + D+++++ + +V + P PA++ Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDY 119 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 C +GWG N + P L+ V + I N CDA Y + DD Sbjct: 120 VYRKSQC--SGWG-TINSGGVCCPAVLRYVTLNITTNAFCDAVY--------TSDTIYDD 168 Query: 209 MLCA----GNTRRDSCQGDSGGPLVCKV-NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 M+CA G T RDSCQGDSGGPL K +G + G+VSWG GCA PG+Y+RV ++ Sbjct: 169 MICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCAS-GYPGVYSRVGFH 227 Query: 264 LDWIHHYVPKK 274 WI + Sbjct: 228 AGWITDTITNN 238 >1SGF-A nrPDB Length = 240 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 107/253 (42%), Gaps = 42/253 (16%) Query: 40 SKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQH---LY 96 + PW V++ Y CGG L+ WVLTAAHC +V L + + Sbjct: 13 NSQPWHVAVYRFNKYQ---CGGVLLDRNWVLTAAHCYNDK------YQVWLGKNNFLEDE 63 Query: 97 YQDQLLPVSRIIVHPQFYT-----------AQIGADIALLELEEPVNVSSHVHTVTLPPA 145 DQ VS+ I HP F D+ LL L +P +++ V +TLP Sbjct: 64 PSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTE 123 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 G C +GWG + P L+ V + ++ N CD + + V Sbjct: 124 EPKL--GSTCLASGWGSTTPI-KFKYPDDLQCVNLKLLPNEDCDKAHEM---------KV 171 Query: 206 RDDMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTY 262 D MLCAG S C+ DSGGPL+C + G+ SWG E C +P P +YT++ Sbjct: 172 TDAMLCAGEMDGGSYTCEHDSGGPLICD----GILQGITSWGPEPCGEPTEPSVYTKLIK 227 Query: 263 YLDWIHHYVPKKP 275 + WI + P Sbjct: 228 FSSWIRETMANNP 240 >1GPZ-A nrPDB Length = 399 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 82/271 (30%), Positives = 135/271 (49%), Gaps = 31/271 (11%) Query: 20 PAPGQAL----QRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC 75 P G+ + QR I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH Sbjct: 143 PVCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHT 197 Query: 76 VGPD---VKDLAALRVQLREQHLYYQDQL--LPVSRIIVHPQFYTA---QIGADIALLEL 127 + P + A+L V L ++ +L P+ R+ VHP + DIALLEL Sbjct: 198 LYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLEL 257 Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187 E V + ++ + LP + G+ +V+G+G ++ L+ V++P+ Sbjct: 258 ENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK----IAHDLRFVRLPVANPQA 313 Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG--TWLQAGVVS 243 C+ + + + +M CAG + ++D+CQGDSGG + W+ G+VS Sbjct: 314 CENWLRG----KNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVS 369 Query: 244 WGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 WG GC++ G YT+V Y+DWI + ++ Sbjct: 370 WGIGCSRG--YGFYTKVLNYVDWIKKEMEEE 398 >5O32-I nrPDB Length = 244 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 84/252 (33%), Positives = 118/252 (46%), Gaps = 25/252 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAAL--RV 88 IVGG+ A PWQV+++ CGG I W+LTAAHC+ + V Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 57 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHV----HTVTLPP 144 + + V RII H + DIAL+E+++ N +P Sbjct: 58 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 117 Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204 + F P C V+GWG ++ER+ F L+ +V ++ N C Y R Sbjct: 118 SPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN--CSKFY--------GNRF 164 Query: 205 VRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261 +M CAG + D+C+GDSGGPLVC N GVVSWGE C +P PG+YT+V Sbjct: 165 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVA 224 Query: 262 YYLDWIHHYVPK 273 Y DWI ++V + Sbjct: 225 NYFDWISYHVGR 236 >1FUJ-A nrPDB Length = 221 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 81/248 (32%), Positives = 118/248 (47%), Gaps = 33/248 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG EA P+ SL++ G HFCGG+LIHP +VLTAAHC+ + L + V L Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRL--VNVVL 58 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q+ Q V+++ ++ + DI L++L P N+S+ V TV LP + Sbjct: 59 GAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQ 117 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 P G C GWG V + PP L+++ V ++ R Sbjct: 118 PVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTVV------------------TFFCRP 157 Query: 208 DMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 264 +C RR + C GDSGGPL+C + G+ S+ GCA P +TRV Y+ Sbjct: 158 HNICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYV 213 Query: 265 DWIHHYVP 272 DWI + Sbjct: 214 DWIRSTLR 221 >1MD7-A nrPDB Length = 328 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 81/269 (30%), Positives = 133/269 (49%), Gaps = 31/269 (11%) Query: 20 PAPGQAL----QRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC 75 P G+ + QR I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH Sbjct: 75 PVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHT 129 Query: 76 VGPD---VKDLAALRVQLREQHLYYQDQL--LPVSRIIVHPQFYTA---QIGADIALLEL 127 + P + A+L V L ++ +L P+ R+ VHP + DIALLEL Sbjct: 130 LYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLEL 189 Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187 E V + ++ + LP + G+ +V+G+G ++ L+ V++P+ Sbjct: 190 ENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK----IAHDLRFVRLPVANPQA 245 Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG--TWLQAGVVS 243 C+ + + + +M CAG + ++D+CQGD+GG + W+ G+VS Sbjct: 246 CENWLRG----KNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVS 301 Query: 244 WGEGCAQPNRPGIYTRVTYYLDWIHHYVP 272 WG GC++ G YT+V Y+DWI + Sbjct: 302 WGIGCSRG--YGFYTKVLNYVDWIKKEME 328 >4E7N-A nrPDB Length = 238 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 76/249 (30%), Positives = 119/249 (47%), Gaps = 23/249 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E ++ + V+L + FCGG+LI+ +WVLTAAHC + + +++ + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTL-FCGGTLINQEWVLTAAHCDRKNFR----IKLGM 55 Query: 91 REQHLYYQDQLLPV--SRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ V + DI L+ L+ PV S H+ + S Sbjct: 56 HSKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSP 113 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C + GWG + E P P V + ++E +C A Y Sbjct: 114 PSVGSVCRIMGWGRISPTEGTYPDVP-HCVNINLLEYEMCRAPYPEFELPA------TSR 166 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLD 265 LCAG +D+C+GDSGGPL+C NG + G+ SWG + CAQP++P YT+V +LD Sbjct: 167 TLCAGILEGGKDTCKGDSGGPLIC--NGQF--QGIASWGDDPCAQPHKPAAYTKVFDHLD 222 Query: 266 WIHHYVPKK 274 WI + + Sbjct: 223 WIENIIAGN 231 >4BXW-A nrPDB Length = 423 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 78/260 (30%), Positives = 123/260 (47%), Gaps = 29/260 (11%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88 + IV G + + PWQ +L FCGG+++ P +VLTAAHC+ + ++ V Sbjct: 168 IRIVNGMDCKLGECPWQAALV--DEKEGVFCGGTILSPIYVLTAAHCINE--TETISVVV 223 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYTAQ---------IGADIALLELEEPVNVSSHVHT 139 ++ LL V +I VH +F Q DIA+++++ P+ S +V Sbjct: 224 GEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVP 283 Query: 140 VTLPPA---SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 LP A ++ V+G+G + E+ P LK +KVP ++ H C Sbjct: 284 ACLPTADFANQVLMKQDFGIVSGFGRIV--EKGPKSKTLKVLKVPYVDRHTCMVSSETP- 340 Query: 197 YTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRP 254 + +M CAG RD+CQGDSGGP T G+VS GEGCA+ + Sbjct: 341 --------ITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKY 392 Query: 255 GIYTRVTYYLDWIHHYVPKK 274 G YT+++ ++ WI + +K Sbjct: 393 GNYTKLSKFIPWIKRIMRQK 412 >2QY0-B nrPDB Length = 242 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 129/256 (50%), Gaps = 27/256 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD---VKDLAALR 87 I+GGQ+A +PWQV +HG GG+L+ +W+LTAAH + P + A+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 88 VQLREQHLYYQDQL--LPVSRIIVHPQFYTA---QIGADIALLELEEPVNVSSHVHTVTL 142 V L ++ +L P+ R+ VHP + DIALLELE V + ++ + L Sbjct: 56 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 115 Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202 P + G+ +V+G+G ++ L+ V++P+ C+ + + Sbjct: 116 PDNDTFYDLGLMGYVSGFGVMEEK----IAHDLRFVRLPVANPQACENWLRG----KNRM 167 Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG--TWLQAGVVSWGEGCAQPNRPGIYT 258 + +M CAG + ++D+CQGDSGG + W+ G+VSWG GC++ G YT Sbjct: 168 DVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRG--YGFYT 225 Query: 259 RVTYYLDWIHHYVPKK 274 +V Y+DWI + ++ Sbjct: 226 KVLNYVDWIKKEMEEE 241 >4GSO-A nrPDB Length = 232 Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 25/247 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ P+ L HG +FCG +LI+ +WV+TAAHC + + L V Sbjct: 1 VLGGDECDINEHPFLAFLYSHG----YFCGLTLINQEWVVTAAHCDSTNFQ--MQLGVHS 54 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 ++ + P + I + + + DI L++L++P++ S H+ ++LP + Sbjct: 55 KKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV- 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C + GWG + P P + +++ +C Y+ L Sbjct: 114 -GSVCRIMGWGSITIPNETYPDVPY-CANINLVDYEVCQGAYNGLPA---------KTTL 162 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLDWI 267 CAG +D+C GDSGGPL+C NG + G+VS+G C Q +PGIYT V Y DWI Sbjct: 163 CAGVLEGGKDTCVGDSGGPLIC--NGQF--QGIVSYGAHSCGQGPKPGIYTNVFDYTDWI 218 Query: 268 HHYVPKK 274 + Sbjct: 219 QRNIAGN 225 >2OLG-A nrPDB Length = 278 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 76/274 (27%), Positives = 119/274 (43%), Gaps = 31/274 (11%) Query: 21 APGQALQRVGIVGGQEAPRSKWPWQVSL--RVHGPYWMHFCGGSLIHPQWVLTAAHCVGP 78 G ++ I+ G + ++PW + + + CGGSLI+ ++++TAAHCV Sbjct: 13 DCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAG 72 Query: 79 DVKDLAAL--RVQLREQHLYYQDQL--------------LPVSRIIVHPQFYTAQIG--A 120 V + +V+L E + L + I HP + Sbjct: 73 RVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYH 132 Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180 DIAL+ L V ++++ V LP +E G V GWG + + +++ V Sbjct: 133 DIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK---QKLAV 189 Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCK-VNGTWLQ 238 P++ C + G VR LCAG + +DSC GDSGGPL+ + N + Sbjct: 190 PVVHAEQCAKTF------GAAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFL 243 Query: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 272 G+VS+G C PGIYT+V Y DWI + Sbjct: 244 EGLVSFGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >1MZD-A nrPDB Length = 240 Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats. Identities = 79/247 (31%), Positives = 122/247 (49%), Gaps = 21/247 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+E P+ S++ G H CGG LI PQWVLTAAHC K + V L Sbjct: 3 IIGGKEVSPHSRPFMASIQYGG---HHVCGGVLIDPQWVLTAAHCQYRFTKGQSPT-VVL 58 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L + Q L + + I + + DI L++L+ ++ HV + + + Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 117 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 + G C VTGWG D + L P L++V V ++ +C+++ + + Sbjct: 118 SLRSGTKCKVTGWGATDP-DSLRPSDTLREVTVTVLSRKLCNSQSYYNGDP-----FITK 171 Query: 208 DMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT-YYL 264 DM+CAG+ ++DSC+GD+GGPL+CK + +VS G C +PGIYT +T Y Sbjct: 172 DMVCAGDAKGQKDSCKGDAGGPLICK----GVFHAIVSGGHECGVATKPGIYTLLTKKYQ 227 Query: 265 DWIHHYV 271 WI + Sbjct: 228 TWIKSNL 234 >1KYN-A nrPDB Length = 235 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 76/248 (30%), Positives = 117/248 (47%), Gaps = 29/248 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+E+ P+ L++ P CGG L+ +VLTAAHC G + + V L Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN------INVTL 54 Query: 91 REQHL---YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ Q + R I HPQ+ I DI LL+L V + +V+ V LP A E Sbjct: 55 GAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQE 114 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG V L++V++ + + C + G+Y Sbjct: 115 GLRPGTLCTVAGWGRVSMRRG---TDTLREVQLRVQRDRQCLRIF--GSYDPR------- 162 Query: 208 DMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +C G+ R+ + +GDSGGPL+C + G+VS+G+ P P ++TRV+ +L Sbjct: 163 RQICVGDRRERKAAFKGDSGGPLLCNN----VAHGIVSYGKSSGVP--PEVFTRVSSFLP 216 Query: 266 WIHHYVPK 273 WI + Sbjct: 217 WIRTTMRS 224 >4IGD-A nrPDB Length = 406 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 75/275 (27%), Positives = 117/275 (42%), Gaps = 33/275 (12%) Query: 17 YAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV 76 P I G+ A + PW L FCGGSL+ W++TAAHC+ Sbjct: 143 CGLP-KFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNG--QPFCGGSLLGSSWIVTAAHCL 199 Query: 77 GPDVKD------------LAALRVQLREQHLY---YQDQLLPVSRIIVHPQFYTAQIGAD 121 + + ++ L + +Q L V +HPQ+ D Sbjct: 200 HQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFEND 259 Query: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181 +AL+EL E +++ V + LP + G V+GWG P L ++++P Sbjct: 260 VALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQFLQR---FPETLMEIEIP 314 Query: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC--KVNGTWL 237 I+++ C Y + V DM+CAG +D+C GDSGGP+V + G W Sbjct: 315 IVDHSTCQKAY------APLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWY 368 Query: 238 QAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 272 G VSWG+ C + +R G+Y+ + + DWI Sbjct: 369 LVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQRVTG 403 >2BDH-A nrPDB Length = 223 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 117/246 (47%), Gaps = 26/246 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+ G++ PWQ +L + FC G L+HPQWVL+AAHC L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSY--TIGLGLHS 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 E Q++ S + HP++ + D+ L++L+E V+ S + ++++ AS+ Sbjct: 56 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPT 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C V+GWG + N P L+ V V ++ +C Y + M Sbjct: 114 AGNSCLVSGWGLLANGRM---PTVLQCVNVSVVSEEVCSKLYDP---------LYHPSMF 161 Query: 211 CAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLDWI 267 CAG ++DSC GDSGGPL+C G+VS+G+ C Q PG+YT + + +WI Sbjct: 162 CAGGGQDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 217 Query: 268 HHYVPK 273 V Sbjct: 218 EKTVQA 223 >2AIQ-A nrPDB Length = 231 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 73/249 (29%), Positives = 116/249 (46%), Gaps = 30/249 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + + +G CGG+LI+ +WVLTA HC +++ + + + Sbjct: 1 VIGGDECNINEHRFLALVYANGS----LCGGTLINQEWVLTARHCDRGNMR----IYLGM 52 Query: 91 REQHLYYQD--QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + +D + P + DI L+ L PV S+H+ ++LP + Sbjct: 53 HNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPS 112 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C + GWG + + P P + I++ +C A Y A Sbjct: 113 V--GSVCRIMGWGTITSPNATLPDVP-HCANINILDYAVCQAAYKGLAA----------T 159 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVS-WGEGCAQPNRPGIYTRVTYYLD 265 LCAG +D+C+GDSGGPL+C NG + G++S G CAQP +PGIYT+V Y D Sbjct: 160 TLCAGILEGGKDTCKGDSGGPLIC--NGQF--QGILSVGGNPCAQPRKPGIYTKVFDYTD 215 Query: 266 WIHHYVPKK 274 WI + Sbjct: 216 WIQSIISGN 224 >4DJZ-B nrPDB Length = 251 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 74/261 (28%), Positives = 116/261 (44%), Gaps = 32/261 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 I G+ A + PW L FCGGSL+ W++TAAHC+ + Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNG--QPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 83 ----LAALRVQLREQHLY---YQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSS 135 + ++ L + +Q L V +HPQ+ D+AL+EL E +++ Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195 V + LP + G V+GWG P L ++++PI+++ C Y Sbjct: 119 FVMPICLPEGPQ--QEGAMVIVSGWGKQFLQR---FPETLMEIEIPIVDHSTCQKAY--- 170 Query: 196 AYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC--KVNGTWLQAGVVSWGEGCAQP 251 + V DM+CAG +D+C GDSGGP+V + G W G VSWG+ C + Sbjct: 171 ---APLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKK 227 Query: 252 NRPGIYTRVTYYLDWIHHYVP 272 +R G+Y+ + + DWI Sbjct: 228 DRYGVYSYIHHNKDWIQRVTG 248 >1ORF-A nrPDB Length = 234 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 117/251 (46%), Gaps = 27/251 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E P+ V L + C G+LI WVLTAAHC +V L Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRS-----QVIL 52 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 + ++ Q++ V + +P + A D+ LL+L E ++ +V + LP + Sbjct: 53 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGD 112 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 PG C V GWG N L++V++ I++ +C+ + H ++ Sbjct: 113 DVKPGTMCQVAGWGRTHNSASW--SDTLREVEITIIDRKVCNDRNHYNFNP-----VIGM 165 Query: 208 DMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVT-Y 262 +M+CAG+ RDSC GDSG PL+C+ + GV S+G C P PG+Y ++ Sbjct: 166 NMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKK 221 Query: 263 YLDWIHHYVPK 273 +L+WI + Sbjct: 222 HLNWIIMTIKG 232 >3RP2-A nrPDB Length = 224 Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 117/245 (47%), Gaps = 24/245 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHF-CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E+ P+ L + + CGG LI Q+VLTAAHC +++ + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC---KGREITVILGA 57 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 + Q + V + I+H + + DI LL+LE+ V ++ V+ V LP S+ Sbjct: 58 HDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFI 117 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PG CW GWG + P + L++V++ IM+ C Y Y Sbjct: 118 HPGAMCWAAGWGKTGVRD--PTSYTLREVELRIMDEKAC-VDYRYYEYKF---------Q 165 Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +C G+ R + GDSGGPL+C + G+VS+G A+P P I+TRV+ Y+ WI Sbjct: 166 VCVGSPTTLRAAFMGDSGGPLLC----AGVAHGIVSYGHPDAKP--PAIFTRVSTYVPWI 219 Query: 268 HHYVP 272 + + Sbjct: 220 NAVIN 224 >3S9B-A nrPDB Length = 234 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 116/249 (46%), Gaps = 27/249 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG E ++ P+ V+L +H C G+LI+ +WVLTAAHC +++ +++ + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCDRRNIR----IKLGM 55 Query: 91 REQHLYYQDQLLPVS--RIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 +++ +D+ + V + + + DI L+ L PV S+H+ V+LP S Sbjct: 56 HSKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRG 115 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C + GWG + P + I+++ C+ Y Sbjct: 116 V--GSRCRIMGWGKISTTT---YPDVPHCTNIFIVKHKWCEPLYPWVPADS--------R 162 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLD 265 LCAG RD+C GDSGGPL+C G+V+ G E C Q +P +YT+V Y + Sbjct: 163 TLCAGILKGGRDTCHGDSGGPLICNGE----MHGIVAGGSEPCGQHLKPAVYTKVFDYNN 218 Query: 266 WIHHYVPKK 274 WI + Sbjct: 219 WIQSIIAGN 227 >2RDL-A nrPDB Length = 226 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 71/247 (28%), Positives = 119/247 (48%), Gaps = 24/247 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPY-WMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+GG E P+ L + P + C G LI +V+TAAHC G + L + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 ++ + Q L V + HP++ + DI LL+L+E N++ V T+ + S + Sbjct: 61 KVKEDTW---QKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSI 117 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 PPG C GWG + +E PP L++VK+ I++ C ++ Sbjct: 118 PPGRVCRAVGWGRTNVNE--PPSDTLQEVKMRILDPQACK----------HFEDFHQEPQ 165 Query: 210 LCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 LC GN ++ + +GDSGGPL+C + G+ S+ A+P P ++TR+++Y WI Sbjct: 166 LCVGNPKKIRNVYKGDSGGPLLC----AGIAQGIASYVLRNAKP--PSVFTRISHYRPWI 219 Query: 268 HHYVPKK 274 + + + Sbjct: 220 NKILREN 226 >1GVZ-A nrPDB Length = 237 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 78/263 (29%), Positives = 113/263 (42%), Gaps = 44/263 (16%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E + PWQV++ G + CGG L+HPQWVLTAAHC+ D ++ L Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQ---CGGVLVHPQWVLTAAHCMSDD------YQIWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYT-----------AQIGADIALLELEEPVNVSSH 136 +L + Q VS + PQF I D+ LL L +P ++ Sbjct: 52 GRHNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDA 111 Query: 137 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 196 V + LP G C+ +GWG + L+ V++ + N C Y Sbjct: 112 VKILDLPTQEPKL--GSTCYTSGWGLISTFTNRG-SGTLQCVELRLQSNEKCARAY---- 164 Query: 197 YTGDDVRIVRDDMLCAGNTRRDS---CQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPN 252 + + +LCA R DS C GDSGG L+C + G+ SWG CA N Sbjct: 165 -----PEKMTEFVLCA-THRDDSGSICLGDSGGALICD----GVFQGITSWGYSECADFN 214 Query: 253 RPGIYTRVTYYLDWIHHYVPKKP 275 ++T+V + WI + K Sbjct: 215 DNFVFTKVMPHKKWIKETIEKNS 237 >1BQY-A nrPDB Length = 234 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 72/247 (29%), Positives = 111/247 (44%), Gaps = 23/247 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 + GG E ++ V L + CGG+LI+ WV+TAAHC + + L V Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGF---LCGGTLINQDWVVTAAHCDSNNFQLL--FGVHS 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 ++ + P + + ++ DI L++L+ V+ S H+ ++ S Sbjct: 56 KKILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPS 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C + GWG + + P P + I+++ +C Y R V + L Sbjct: 114 VGSVCRIMGWGKTIPTKEIYPDVP-HCANINILDHAVCRTAYSW--------RQVANTTL 164 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLDWI 267 CAG RD+C DSGGPL+C + G+VSWG C QP PG+YT+V YLDWI Sbjct: 165 CAGILQGGRDTCHFDSGGPLICN----GIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWI 220 Query: 268 HHYVPKK 274 + Sbjct: 221 KSIIAGN 227 >3I77-A nrPDB Length = 230 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 109/241 (45%), Gaps = 22/241 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V L FCGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMVRLI--NEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P F G D AL++L +P+N + T TF Sbjct: 59 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF- 117 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + +V ++M+ Sbjct: 118 -----TVAGWGA--NREGGSQQRYLLKANVPFVSDAACRSSSSF--------ILVANEMI 162 Query: 211 CAGN---TRRDSCQGDSGGPLVCKVN-GTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266 CAG D+CQGDSGGP+ K N W+Q G+VSWG GCA+P PG+YT V+ + Sbjct: 163 CAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASA 222 Query: 267 I 267 I Sbjct: 223 I 223 >1EQ9-A nrPDB Length = 222 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 118/244 (48%), Gaps = 23/244 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++AP K+P+QVSLR+ G H CG S++ VLTAAHCV + +L L+V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGS---HRCGASILDNNNVLTAAHCVDG-LSNLNRLKVHV 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 +L + V +V+ + + D+AL+ L P+ + V + L E Sbjct: 57 GTNYLSESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 PC +TGWG P L+++++ + C+ V D + Sbjct: 117 SN-PCTLTGWGSTRLGGNTPNA--LQEIELIVHPQKQCERDQWR----------VIDSHI 163 Query: 211 CAGNTRRD-SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHH 269 C R + +C GDSGGPLV Q G+VS+G CA P +YTRV+ ++ WI+ Sbjct: 164 CTLTKRGEGACHGDSGGPLV----ANGAQIGIVSFGSPCAL-GEPDVYTRVSSFVSWINA 218 Query: 270 YVPK 273 + K Sbjct: 219 NLKK 222 >5LPF-A nrPDB Length = 234 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 106/251 (42%), Gaps = 33/251 (13%) Query: 34 GQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ 93 G R PWQVSL + C G L+ WVLTAAHC RV Sbjct: 7 GSPCARGSQPWQVSLFNGLSFH---CAGVLVDQSWVLTAAHC----GNKPLWARVGDDHL 59 Query: 94 HLYYQDQLLPVSRIIVHPQFY--------TAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 L +QL +R +VHP+++ D+ LL+L PV + V + LP Sbjct: 60 LLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPY- 118 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 PG C V GWG R+ L + I+ C+ Y +V Sbjct: 119 -RCAQPGDQCQVAGWGTTAAR-RVKYNKGLTCSSITILSPKECEVFY---------PGVV 167 Query: 206 RDDMLCAG-NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYY 263 ++M+CAG + +D CQ DSGGPLVC G++SWG C P +YT++ Y Sbjct: 168 TNNMICAGLDRGQDPCQSDSGGPLVCDE----TLQGILSWGVYPCGSAQHPAVYTQICKY 223 Query: 264 LDWIHHYVPKK 274 + WI+ + Sbjct: 224 MSWINKVIRSN 234 >2ZKS-A nrPDB Length = 240 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 73/247 (29%), Positives = 115/247 (46%), Gaps = 21/247 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+E P+ SL+ +G H CGG L+HP+WVLTAAHC+ + +A LR+ L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGS---HLCGGVLVHPKWVLTAAHCL---AQRMAQLRLVL 54 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT-AQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 L + I HP++ + D+ALL+L+ V S + + LP + Sbjct: 55 GLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 114 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 G C + GWG RL L+++ + +++ +C+ + M Sbjct: 115 AAGTRCSMAGWGLTHQGGRL--SRVLRELDLQVLDTRMCNNSRFWNGS-------LSPSM 165 Query: 210 LCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDW 266 +C +D C+GDSGGPLVC + AGV+S+ C +P + T V Y+ W Sbjct: 166 VCLAADSKDQAPCKGDSGGPLVCGK--GRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSW 223 Query: 267 IHHYVPK 273 I + Sbjct: 224 IRKVTGR 230 >1OP0-A nrPDB Length = 234 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 73/247 (29%), Positives = 117/247 (47%), Gaps = 23/247 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + V+ + FCGG+LI+P+WV+TAAHC D + L V Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGF---FCGGTLINPEWVVTAAHCDSTDFQ--MQLGVHS 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 ++ + P + I + + DI L++L++P++ S H+ ++ S Sbjct: 56 KKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPS 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G C + GWG + + P P + ++++ +C A Y L Sbjct: 114 VGSVCRIMGWGSITPVKETFPDVPY-CANINLLDHAVCQAGYPELLAEY--------RTL 164 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLDWI 267 CAG +D+C GDSGGPL+C NG + G+VS+G C Q +PGIYT V Y DWI Sbjct: 165 CAGIVQGGKDTCGGDSGGPLIC--NGQF--QGIVSYGAHPCGQGPKPGIYTNVFDYTDWI 220 Query: 268 HHYVPKK 274 + Sbjct: 221 QRNIAGN 227 >4LK4-A nrPDB Length = 357 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 74/249 (29%), Positives = 115/249 (46%), Gaps = 16/249 (6%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGP--YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87 I+ G A ++WP V+L G Y FCGGS + ++VLTAAHC + Sbjct: 10 RIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDVI 69 Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL--PPA 145 + + + Q + + +I H + + + DIA++EL + +S + +TL P Sbjct: 70 IGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPAITLAGPAT 125 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 + P P V GWG + L++V V ++ +C G + Sbjct: 126 RTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDP----- 180 Query: 206 RDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYL 264 CA +DSCQGD+GGP+V K Q G+VSWG E CA+ G+YT V+Y+ Sbjct: 181 NSTNFCAARLTKDSCQGDAGGPIVVKTGRE--QLGIVSWGDEQCAKTGTYGVYTNVSYFR 238 Query: 265 DWIHHYVPK 273 DWI + + Sbjct: 239 DWITKHTNQ 247 >4Q7Y-A nrPDB Length = 250 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 79/251 (31%), Positives = 115/251 (45%), Gaps = 28/251 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG E P+ S+R G H CGG L+ +WV++AAHC +DL V L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCFS--HRDLRTGLVVL 55 Query: 91 REQHLY---YQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 L Q+ + + HP ++ DI LL L + V + LP Sbjct: 56 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRA 115 Query: 148 TFP-PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206 P G C V GWG V + E LPP L + KV +++ +C++ + + Sbjct: 116 RPPTAGTRCRVAGWGFVSDFEELPPG--LMEAKVRVLDPDVCNSSWK---------GHLT 164 Query: 207 DDMLCA--GNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSW-GEGCAQPNRPGIYTRVTY 262 MLC G++ RR C DSGGPLVC+ G+VS+ G C P P +YT+V+ Sbjct: 165 LTMLCTRSGDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSA 220 Query: 263 YLDWIHHYVPK 273 ++ WI V + Sbjct: 221 FVAWIWDVVRR 231 >2XXL-A nrPDB Length = 408 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 76/276 (27%), Positives = 111/276 (40%), Gaps = 41/276 (14%) Query: 26 LQRVGIVGGQEAPRSKWPWQVSLRVHG-PYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLA 84 + G E S PW LR CGG++I +++LTAAHCV DL Sbjct: 114 FLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDL- 172 Query: 85 ALRVQLREQHLYYQDQL---------------LPVSRIIVHPQFYTAQIGADIALLELEE 129 ++L E + ++ + + + ++H ++ I DIALL+L Sbjct: 173 -YEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNR 231 Query: 130 PVNVSSHVHTVTLPPASETFPPG---MPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENH 186 V H+ + LP E +VTGWG +N L Q VP+ Sbjct: 232 SVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENG---SSSDVLLQANVPLQPRS 288 Query: 187 ICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPL------VCKVNGTWLQA 239 C Y R V LC G +DSC+GDSGGPL + + ++ Sbjct: 289 ACSQAYR---------RAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEF 339 Query: 240 GVVSWG-EGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 G+VS G C Q + PG+YT V Y+ WI + Sbjct: 340 GIVSQGVVTCGQISLPGLYTNVGEYVQWITDTMASN 375 >3BEU-A nrPDB Length = 224 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 73/240 (30%), Positives = 110/240 (45%), Gaps = 26/240 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V L + CGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P F G D AL++L +P+N + T TF Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGTF- 112 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + +V ++M+ Sbjct: 113 -----TVAGWGA--NREGGSQQRYLLKANVPFVSDAACRSSSSF--------ILVANEMI 157 Query: 211 CAGNTRR--DSCQGDSGGPLVCKVN-GTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG + D+CQGDSGGP+ K N W+Q G+VSWGEGCA+ + G+YT V+ + I Sbjct: 158 CAGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAI 217 >3S69-A nrPDB Length = 234 Score = 209 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 117/249 (46%), Gaps = 27/249 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ V+ + FC G+LI+ +WVLTAAHC + + +++ + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGF---FCSGTLINEEWVLTAAHCDNTNFQ----MKLGV 53 Query: 91 REQHLYYQDQLL--PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + + +D+ P + I + + DI L++L+ V+ S H+ V L S Sbjct: 54 HSKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSP 111 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C + GWG + + P P + ++++ +C A Y + Sbjct: 112 PSVGSVCHIMGWGSITPIKVTYPDVPY-CAYINLLDDAVCQAGYPE--------LLTEYR 162 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTYYLD 265 LCAG +D+C GDSGGPL+C NG + G+VS+G C Q +PG+YT+V Y Sbjct: 163 TLCAGILEGGKDTCGGDSGGPLIC--NGQF--QGIVSFGAHPCGQGLKPGVYTKVFDYNH 218 Query: 266 WIHHYVPKK 274 WI + Sbjct: 219 WIQSIIAGN 227 >1AZZ-A nrPDB Length = 226 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 90/251 (35%), Positives = 123/251 (49%), Gaps = 31/251 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG EA + WP Q +L + M+FCGGSLI P+W+LTAAHC+ + V L Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDG----AGFVDVVL 53 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 ++ + + + VH + + I DIA++ L PV +++ + TV LP Sbjct: 54 GAHNIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD- 112 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 G TGWG + +D L L+QV VPIM N CDA Y IV D Sbjct: 113 -VGVGTVVTPTGWG-LPSDSALGISDVLRQVDVPIMSNADCDAVYG----------IVTD 160 Query: 208 DMLCAGN-TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVTYYL 264 +C + + +C GDSGGPL N L G+ S+G GC + P +TRVTY+L Sbjct: 161 GNICIDSTGGKGTCNGDSGGPL----NYNGLTYGITSFGAAAGC-EAGYPDAFTRVTYFL 215 Query: 265 DWIHHYVPKKP 275 DWI P Sbjct: 216 DWIQTQTGITP 226 >2ASU-B nrPDB Length = 234 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 112/249 (44%), Gaps = 30/249 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG PW VSLR HFCGGSL+ QW+LTA C L V L Sbjct: 1 VVGGH---PGNSPWTVSLRNRQG--QHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 91 RE-----QHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 QH Q +PV++++ P G+ + LL+LE V ++ V + LPP Sbjct: 56 GTLFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPE 109 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 PPG C + GWG+ L + ++ N C+ K+ V Sbjct: 110 WYVVPPGTKCEIAGWGETKGTGN---DTVLNVALLNVISNQECNIKHR---------GRV 157 Query: 206 RDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263 R+ +C +C+GD GGPL C + +W+ G++ CA+ P ++TRV+ + Sbjct: 158 RESEMCTEGLLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVF 217 Query: 264 LDWIHHYVP 272 +DWIH + Sbjct: 218 VDWIHKVMR 226 >4X0L-C nrPDB Length = 259 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 68/277 (24%), Positives = 113/277 (40%), Gaps = 38/277 (13%) Query: 17 YAAP-APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAA-- 73 P P +QR I+GG + +PWQ + H G +LI+ QW+LT A Sbjct: 2 CGKPKNPANPVQR--ILGGHLDAKGSFPWQAKMVSHHNL---TTGATLINEQWLLTTAKN 56 Query: 74 ----HCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEE 129 H KD+A + QL+ + ++++HP + DI L++L++ Sbjct: 57 LFLNHSENATAKDIAPTLTLY-----VGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQ 107 Query: 130 PVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICD 189 V+V+ V + LP G +V+GWG + LK V +P+ + C Sbjct: 108 KVSVNERVMPICLPSKDYA-EVGRVGYVSGWGR---NANFKFTDHLKYVMLPVADQDQCI 163 Query: 190 AKY--------HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKV--NGTWL 237 Y I+ + CAG ++ D+C GD+G TW Sbjct: 164 RHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWY 223 Query: 238 QAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 G++S+ + CA G+Y +VT DW+ + + Sbjct: 224 ATGILSFDKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 70/285 (24%), Positives = 116/285 (40%), Gaps = 39/285 (13%) Query: 9 LPVLASRAYAAP-APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQ 67 LP + P P +QR I+GG + +PWQ + H G +LI+ Q Sbjct: 51 LPECEA-VCGKPKNPANPVQR--ILGGHLDAKGSFPWQAKMVSHHNL---TTGATLINEQ 104 Query: 68 WVLTAA------HCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGAD 121 W+LT A H KD+A + QL+ + ++++HP + D Sbjct: 105 WLLTTAKNLFLNHSENATAKDIAPTLTLY-----VGKKQLVEIEKVVLHPNYSQV----D 155 Query: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181 I L++L++ V+V+ V + LP G +V+GWG + LK V +P Sbjct: 156 IGLIKLKQKVSVNERVMPICLPSKDYA-EVGRVGYVSGWGR---NANFKFTDHLKYVMLP 211 Query: 182 IMENHICDAKY--------HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCK 231 + + C Y I+ + CAG ++ D+C GD+G Sbjct: 212 VADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVH 271 Query: 232 V--NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 TW G++S+ + CA G+Y +VT DW+ + + Sbjct: 272 DLEEDTWYATGILSFDKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 315 >4F4O-C nrPDB Length = 347 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 78/286 (27%), Positives = 122/286 (42%), Gaps = 41/286 (14%) Query: 9 LPVLASRAYAAP-APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQ 67 LP + P P +QR I+GG + +PWQ + H G +LI+ Q Sbjct: 83 LPECEA-VCGKPKNPVDQVQR--IMGGSLDAKGSFPWQAKMISHHNL---TSGATLINEQ 136 Query: 68 WVLTAA------HCVGPDVKDLA-ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120 W+LT A H KD+A LR+ + + Q + + ++I HP T Sbjct: 137 WLLTTAKNLRLGHKNDTKAKDIAPTLRLYVG------KKQEVEIEKVIFHPDNSTV---- 186 Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180 DI L++L++ V V+ V + LP G+ +V+GWG + L LK V + Sbjct: 187 DIGLIKLKQKVPVNERVMPICLPSKDY-VNVGLVGYVSGWGR---NANLNFTEHLKYVML 242 Query: 181 PIMENHICDAKY--------HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVC 230 P+ + C Y I+ + CAG ++ D+C GD+G Sbjct: 243 PVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAV 302 Query: 231 --KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 K + TW AG++S+ + C + G+Y RVT LDWI + Sbjct: 303 HDKDDDTWYAAGILSFDKSC-RTAEYGVYVRVTSILDWIQTTIADN 347 >1PQ7-A nrPDB Length = 224 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 77/240 (32%), Positives = 109/240 (45%), Gaps = 21/240 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG A +P+ VS+ +G W CGGSL++ VLTAAHCV + + +++ Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPW---CGGSLLNANTVLTAAHCVSGYAQ--SGFQIRA 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 +S + VHP + D+A+L+L + ++ L + Sbjct: 56 GSLSRTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPV 113 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G V GWG P L +V VPI+ C A+Y A + + M Sbjct: 114 AGSSATVAGWGATSEGGS-STPVNLLKVTVPIVSRATCRAQYGTSA--------ITNQMF 164 Query: 211 CAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIH 268 CAG + +DSCQGDSGGP+V N G VSWG GCA+PN G+Y V +I Sbjct: 165 CAGVSSGGKDSCQGDSGGPIVDSSN---TLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >2FMJ-A nrPDB Length = 222 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 72/240 (30%), Positives = 109/240 (45%), Gaps = 28/240 (11%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 +VGG A + ++P+ V L + CGG+L VLTAAHCV + + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + ++++ P + G D AL++L +P+N + T TF Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLAQPINQPTLKIATTTAYNQGTF- 110 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 V GWG N E L + VP + + C + Y +V ++ + Sbjct: 111 -----TVAGWGA--NREGGSQQRYLLKANVPFVSDAACRSAY--------GNELVANEEI 155 Query: 211 CAGN--TRRDSCQGDSGGPLVCKVN-GTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG D+CQGDSGGP+ K N W+Q G+VSWGEGCA+ + G+YT V+ + I Sbjct: 156 CAGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAI 215 >5KWM-A nrPDB Length = 230 Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 78/246 (31%), Positives = 112/246 (45%), Gaps = 25/246 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++A P+ V+L P FCGG+L P V+TAAHC + V Sbjct: 1 IVGGEDANVQDHPFTVALVT--PDGQQFCGGTLAAPNKVVTAAHC-TVGSQPADINVVSG 57 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET-F 149 R + + V+ + VHP++ A G D+++L LE PV + L A + + Sbjct: 58 RTVMSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGY 113 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 P + GWG+ + L++ VP+ + C Y D M Sbjct: 114 APDTAATILGWGNTSEGGQ--QADHLQKATVPVNSDDTCKQAYG---------EYTPDAM 162 Query: 210 LCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 +CAG D+CQGDSGGP+V GV SWGEGCA+P +PG+Y RV Y D + Sbjct: 163 VCAGVPEGGVDTCQGDSGGPMVVNNK----LIGVTSWGEGCARPGKPGVYARVGAYYDVL 218 Query: 268 HHYVPK 273 + Sbjct: 219 MEQINA 224 >1M9U-A nrPDB Length = 241 Score = 196 bits (499), Expect = 7e-51, Method: Composition-based stats. Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 16/245 (6%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG A ++PWQ+S + W H CG SL+ L+A+HCV + + + L Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQ--IGADIALLELEEPVNVSSHVHTVTLPPASET 148 +Q Q V +H + DIA+L L +++ ++ LP + Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C ++GWG D LP L++ +P++ C A A G + D+ Sbjct: 121 DYAGTTCVISGWGRTDGTNNLP--DILQKSSIPVITTAQCTA-----AMVGVGGANIWDN 173 Query: 209 MLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSW----GEGCAQPNRPGIYTRVTY 262 +C + ++ C GDSGGPL C GT + GV SW G G P+ P +YTRV+ Sbjct: 174 HICVQDPAGNTGACNGDSGGPLNCPDGGTRV-VGVTSWVVSSGLGACLPDYPSVYTRVSA 232 Query: 263 YLDWI 267 YL WI Sbjct: 233 YLGWI 237 >5XRF-A nrPDB Length = 242 Score = 194 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 31/252 (12%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 ++GG E ++ + + P W C G+LIH +WVL AAHC + + + + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRP-WTFQCAGTLIHEEWVLAAAHCYKRGLN----IYLGM 61 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYT-----AQIGADIALLELEEPVNVSSHVHTVTLPPA 145 Q + + D+ R + +Y + D+ LL+L +PV+ S+H+ ++ Sbjct: 62 HNQSIQFDDEQ---RRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LP 116 Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 S G C V GWG + + + + P P + ++ C A Y Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVP-HCANINLLNYMECVAHYPDVPE-------- 167 Query: 206 RDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRPGIYTRVTY 262 +LCAG D+C DSGGPL+C G+V +G CAQPN+PG+YTRV+ Sbjct: 168 TTRLLCAGVLEGGIDTCNQDSGGPLICD----GQFQGIVFFGKYPCAQPNKPGLYTRVSN 223 Query: 263 YLDWIHHYVPKK 274 Y DWI + + K Sbjct: 224 YNDWIQNIIAGK 235 >2HLC-A nrPDB Length = 230 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 75/250 (30%), Positives = 112/250 (44%), Gaps = 27/250 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHF-CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 I+ G EA +P+Q L + CGGSLI +W+LTAAHCV D ++ V Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVH----DAVSVVVY 56 Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 L Y + ++ RII H F D+AL+++ V + ++ + LP E Sbjct: 57 LGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELN 115 Query: 150 PPGMPCW--VTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 W V+GWG + D L+ +++N C +Y G I+ + Sbjct: 116 NKFENIWATVSGWGQSNTD-----TVILQYTYNLVIDNDRCAQEYPPG--------IIVE 162 Query: 208 DMLCAG-NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVTYYL 264 +C + + C GDSGGP V L GVVS+ G GC + +P ++RVT Y+ Sbjct: 163 STICGDTSDGKSPCFGDSGGPFVLSDKN--LLIGVVSFVSGAGC-ESGKPVGFSRVTSYM 219 Query: 265 DWIHHYVPKK 274 DWI K Sbjct: 220 DWIQQNTGIK 229 >1SI5-H nrPDB Length = 240 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 82/246 (33%), Positives = 112/246 (45%), Gaps = 25/246 (10%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89 +V G + W VSLR H CGGSLI WVLTA C D+KD A Sbjct: 1 VVNGIPTRTN-IGWMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAWLGI 56 Query: 90 LREQHLYYQD--QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147 + Q+L VS+++ P+ G+D+ L++L P + V T+ LP Sbjct: 57 HDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGS 110 Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207 T P C V GWG + L+ + IM N C + + + Sbjct: 111 TIPEKTSCSVYGWGYT---GLINYDGLLRVAHLYIMGNEKCSQHHR-------GKVTLNE 160 Query: 208 DMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265 +CAG + S C+GD GGPLVC+ + + GV+ G GCA PNRPGI+ RV YY Sbjct: 161 SEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAK 220 Query: 266 WIHHYV 271 WIH + Sbjct: 221 WIHKII 226 >1PPF-E nrPDB Length = 218 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 64/246 (26%), Positives = 102/246 (41%), Gaps = 32/246 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG+ A WP+ VSL++ G HFCG +LI P +V++AAHCV + + Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 91 RE-QHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 Q+ V RI + + DI +L+L ++++V LP Sbjct: 58 HNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 116 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 G+ C GWG + + + L+++ V ++ + R Sbjct: 117 GNGVQCLAMGWGLLGRNRGI--ASVLQELNVTVV------------------TSLCRRSN 156 Query: 210 LCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLDW 266 +C R + C GDSG PLVC L G+ S+ GCA P + V +++W Sbjct: 157 VCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNW 212 Query: 267 IHHYVP 272 I + Sbjct: 213 IDSIIQ 218 >1AE5-A nrPDB Length = 225 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 108/250 (43%), Gaps = 35/250 (14%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IVGG++A ++P+ S++ G HFCGG+LIH ++V+TAA C ++ + + Sbjct: 1 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 91 REQHLYY--QDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148 + Q +S + + Q D+ LL+L+ N++S V + LP + T Sbjct: 58 YDLRRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208 G C V GWG + RL + V V + C R + Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFP--RFVNVTVTPEDQC-----------------RPN 157 Query: 209 MLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLD 265 +C G R C GD G PLVC+ L GV S+ G C + P +TRV + D Sbjct: 158 NVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVALFRD 211 Query: 266 WIHHYVPKKP 275 WI + P Sbjct: 212 WIDGVL-NNP 220 >3H7O-A nrPDB Length = 228 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 60/244 (24%), Positives = 98/244 (40%), Gaps = 19/244 (7%) Query: 33 GGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLRE 92 GG++ + PW V++R + CGG+++ +VLTAAHCV + + +Q Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPET--IVIQYES 59 Query: 93 QHLYYQDQLLPVSRIIVHPQFYT-AQIGADIALLELEEPVNVSSHV-HTVTLPPASETFP 150 +L+ V+ FY + DIA+LEL P+ + LP Sbjct: 60 TNLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 151 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 210 G V+G+GD + P LK ++ +++ C KY + + Sbjct: 120 TGSDVLVSGYGDGQTMD--PKDHDLKSAQLTVVDLDECRTKY--------GPIFLSLQVF 169 Query: 211 CAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270 CA GD+G P V + + A EG P ++T+V Y+ WI Sbjct: 170 CAQKVGVSLESGDAGDPTVQQDTLVGVAAYFPKRPEGA-----PEVFTKVGSYVSWIQDI 224 Query: 271 VPKK 274 + KK Sbjct: 225 IKKK 228 >1DLE-A nrPDB Length = 298 Score = 173 bits (438), Expect = 1e-43, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 106/267 (39%), Gaps = 52/267 (19%) Query: 18 AAPAPGQALQRVGIV--GGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAH 74 A P Q+L G+V + K PWQ + V P H C G+++ +VLTAAH Sbjct: 1 ADPDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAH 60 Query: 75 CVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY---------TAQIGADIALL 125 C D K+ + ++V + + + L + ++ HP + D+AL+ Sbjct: 61 CFTVDDKEHS-IKVSVG-----GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALI 114 Query: 126 ELEEPVNVSSHVHTVTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180 +L+ + + + LP T PP C E L P +K + V Sbjct: 115 KLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFV 167 Query: 181 PIMENH---------------ICD--AKYHLGAYTGDDV-RIVRDDMLCAGNTRR----D 218 E C+ A+Y G D+ +V LC G + Sbjct: 168 SEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPN 227 Query: 219 SCQGDSGGPLVCKVNGTWLQAGVVSWG 245 +C+GDSGGPL+ ++Q GV+SWG Sbjct: 228 TCRGDSGGPLIVHKRSRFIQVGVISWG 254 >3H7T-A nrPDB Length = 235 Score = 170 bits (432), Expect = 5e-43, Method: Composition-based stats. Identities = 54/247 (21%), Positives = 104/247 (42%), Gaps = 19/247 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+++ +K PW V + V FCGGS++ +V+TAA CV D + + + Sbjct: 1 IIGGKKSDITKEPWAVGVLVD---EKPFCGGSILTANFVITAAQCV--DGTKPSDISIHY 55 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSS-HVHTVTLPPASETF 149 + + + +I + +++ + + A++E E P+ + + LP Sbjct: 56 GSSYRTTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDP 114 Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 P V+GWG N + L L + +++ C+ +Y + + + D + Sbjct: 115 EPDTSVLVSGWGST-NFKSLEYSGDLMEANFTVVDRKSCEEQYK----QIEADKYIYDGV 169 Query: 210 LCAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 CAG ++ GD+G P V + + + S P ++ RV YY+ I Sbjct: 170 FCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMPS-----EFPSVFLRVGYYVLDI 224 Query: 268 HHYVPKK 274 + K Sbjct: 225 KDIISGK 231 >2WIN-I nrPDB Length = 507 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 52/264 (19%) Query: 21 APGQALQRVGIV--GGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVG 77 Q+L G+V + K PWQ + V P H C G+++ +VLTAAHC Sbjct: 211 DESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFT 270 Query: 78 PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY---------TAQIGADIALLELE 128 D K+ + ++V + + + L + ++ HP + D+AL++L+ Sbjct: 271 VDDKEHS-IKVSVG-----GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLK 324 Query: 129 EPVNVSSHVHTVTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183 + + + LP T PP C E L P +K + V Sbjct: 325 NKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEE 377 Query: 184 ENH---------------ICD--AKYHLGAYTGDDV-RIVRDDMLCAGNTRR----DSCQ 221 E C+ A+Y G D+ +V LC G ++C+ Sbjct: 378 EKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCR 437 Query: 222 GDSGGPLVCKVNGTWLQAGVVSWG 245 GDSGGPL+ ++Q GV+SWG Sbjct: 438 GDSGGPLIVHKRSRFIQVGVISWG 461 >2PKA-B nrPDB Length = 152 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 19/166 (11%) Query: 114 YTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDND-ERLPPP 172 D+ LL L+ P ++ V + LP G C +GWG ++ + P Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 173 FPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN--TRRDSCQGDSGGPLVC 230 ++ V++ +++N C + V + MLCAG +D+C GDSGGPL+C Sbjct: 60 DEIQCVQLTLLQNTFCADAH---------PDKVTESMLCAGYLPGGKDTCMGDSGGPLIC 110 Query: 231 KVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275 NG W G+ SWG C N+P IYT++ +YLDWI + + P Sbjct: 111 --NGMW--QGITSWGHTPCGSANKPSIYTKLIFYLDWIDDTITENP 152 >2OK5-A nrPDB Length = 752 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 52/264 (19%) Query: 21 APGQALQRVGIV--GGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVG 77 Q+L G+V + K PWQ + V P H C G+++ +VLTAAHC Sbjct: 455 DESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFT 514 Query: 78 PDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY---------TAQIGADIALLELE 128 D K+ + ++V + + + L + ++ HP + D+AL++L+ Sbjct: 515 VDDKEHS-IKVSVG-----GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLK 568 Query: 129 EPVNVSSHVHTVTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183 + + + LP T PP C E L P +K + V Sbjct: 569 NKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEE 621 Query: 184 ENH---------------ICD--AKYHLGAYTGDDV-RIVRDDMLCAGNTRR----DSCQ 221 E C+ A+Y G D+ +V LC G ++C+ Sbjct: 622 EKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCR 681 Query: 222 GDSGGPLVCKVNGTWLQAGVVSWG 245 GDSGGPL+ ++Q GV+SWG Sbjct: 682 GDSGGPLIVHKRSRFIQVGVISWG 705 >2I6S-A nrPDB Length = 517 Score = 163 bits (414), Expect = 5e-41, Method: Composition-based stats. Identities = 68/242 (28%), Positives = 107/242 (44%), Gaps = 31/242 (12%) Query: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88 VG + + + + PW V+++ P C G+LI QWVLTAAHC D D + RV Sbjct: 230 VGNMSANASDQERTPWHVTIK---PKSQETCRGALISDQWVLTAAHCF-RDGNDHSLWRV 285 Query: 89 QLREQHLYYQDQLLPVSRIIVHPQFYT---------AQIGADIALLELEEPVNVSSHVHT 139 + + + + L + + ++ P F G DIALL+L + V +S+H Sbjct: 286 NVGDPKSQWGKEFL-IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARP 344 Query: 140 VTLPPASETF-----PPGMPCWVTGWGDVDNDERLPPPFP-LKQVKVPI-----MENHIC 188 + LP E P G C ++ N + +P F L K+ I +E C Sbjct: 345 ICLPCTMEANLALRRPQGSTCR-DHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSC 403 Query: 189 ----DAKYHLGAYTGDDVRIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVS 243 + + D +V D LC+G +S C+G+SGG + + + Q G+VS Sbjct: 404 AEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVS 463 Query: 244 WG 245 WG Sbjct: 464 WG 465 >5XW8-A nrPDB Length = 133 Score = 153 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 50/138 (36%), Positives = 74/138 (53%), Gaps = 15/138 (10%) Query: 30 GIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89 IVGG + P+QVSL HFCGGSLI+ QWV++AAHC + ++V+ Sbjct: 8 KIVGGYTCAANSIPYQVSLNSGS----HFCGGSLINSQWVVSAAHCYK------SRIQVR 57 Query: 90 LREQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146 L E + L +Q + ++II HP F + DI L++L P ++S V TV+LP + Sbjct: 58 LGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS- 116 Query: 147 ETFPPGMPCWVTGWGDVD 164 G C ++GWG+ Sbjct: 117 -CAAAGTECLISGWGNTK 133 >3VGC-B nrPDB Length = 131 Score = 153 bits (386), Expect = 8e-38, Method: Composition-based stats. Identities = 49/133 (36%), Positives = 69/133 (51%), Gaps = 4/133 (3%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 IV G+EA WPWQVSL+ + HFCGGSLI+ WV+TAAHC + + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGF--HFCGGSLINENWVVTAAHC--GVTTSDVVVAGEF 56 Query: 91 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFP 150 + + Q L ++++ + ++ + I DI LL+L + S V V LP AS+ F Sbjct: 57 DQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 116 Query: 151 PGMPCWVTGWGDV 163 G C TGWG Sbjct: 117 AGTTCVTTGWGLT 129 >2JET-B nrPDB Length = 128 Score = 150 bits (378), Expect = 9e-37, Method: Composition-based stats. Identities = 48/131 (36%), Positives = 66/131 (50%), Gaps = 4/131 (3%) Query: 34 GQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQ 93 G++A WPWQVSL+ + HFCGGSLI WV+TAAHC + + + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGF--HFCGGSLISEDWVVTAAHC--GVKTSDVVVAGEFDQG 56 Query: 94 HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGM 153 Q+L ++++ +P+F + DI LL+L P S V V LP + FPPG Sbjct: 57 SDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGT 116 Query: 154 PCWVTGWGDVD 164 C TGWG Sbjct: 117 VCATTGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 48/148 (32%), Positives = 73/148 (49%), Gaps = 13/148 (8%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I +HP++ + DIAL++L++PV S ++H V Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGDVDND 166 LP A+ G VTGWG++ Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 49/144 (34%), Positives = 74/144 (51%), Gaps = 13/144 (9%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-------- 82 IV GQ+A PWQV L P + CG SLI +WVLTAAHC+ D Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 83 LAALRVQLREQHLYYQDQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVT 141 L + R ++ +++ + +I +HP++ + DIALL+L+ P+ +S ++H V Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 142 LP---PASETFPPGMPCWVTGWGD 162 LP A++ G VTGWG+ Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGN 143 >1AKS-B nrPDB Length = 98 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 15/111 (13%) Query: 166 DERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGD 223 P L+ +K P++ N C + Y + +M+C G +DSCQGD Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSY---------PGQITGNMICVGFLQGGKDSCQGD 51 Query: 224 SGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 SGGP+VC G+VSWG GCAQ N+PG+YT+V Y++WI + Sbjct: 52 SGGPVVCN----GQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1BBR-E nrPDB Length = 109 Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats. Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 16/110 (14%) Query: 171 PPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSG 225 P L+ V +P++E +C A + D+M CAG R D+C+GDSG Sbjct: 6 QPSVLQVVNLPLVERPVCKAS---------TRIRITDNMFCAGYKPGEGKRGDACEGDSG 56 Query: 226 GPLVCK--VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GP V K N W Q G+VSWGEGC + + G YT V WI + + Sbjct: 57 GPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2HNT-F nrPDB Length = 105 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 16/110 (14%) Query: 171 PPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG-----NTRRDSCQGDSG 225 P L+ V +PI+E +C + D+M CAG R D+C+GDSG Sbjct: 2 QPSVLQVVNLPIVERPVCK---------DSTRIRITDNMFCAGYKPDEGKRGDACEGDSG 52 Query: 226 GPLVCKV--NGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273 GP V K N W Q G+VSWGEGC + + G YT V WI + + Sbjct: 53 GPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >3RU4-E nrPDB Length = 96 Score = 120 bits (300), Expect = 9e-28, Method: Composition-based stats. Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 9/105 (8%) Query: 170 PPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLV 229 P L+Q +P++ N C + ++D M+CAG + SC GDSGGPLV Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWG---------TKIKDAMICAGASGVSSCMGDSGGPLV 51 Query: 230 CKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 CK NG W G+VSWG + PG+Y RVT ++W+ + Sbjct: 52 CKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 96 >2JET-C nrPDB Length = 99 Score = 120 bits (300), Expect = 9e-28, Method: Composition-based stats. Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 9/106 (8%) Query: 169 LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPL 228 L P L+Q +PI+ C + + D M CAG + DSC GDSGGPL Sbjct: 3 LKTPEKLQQAALPIVSEADCKKSWG---------SKITDVMTCAGASGVDSCMGDSGGPL 53 Query: 229 VCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK 274 VC+ +G W AG+VSWG G + PG+Y+RVT + W+ + Sbjct: 54 VCQKDGVWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILEAN 99 >1EPT-B nrPDB Length = 82 Score = 98.5 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 84 AALRVQLREQH---LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTV 140 + ++V+L E + L +Q + ++II HP F + DI L++L P ++S V TV Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 141 TLPPASETFPPGMPCWVTGWGDVD 164 +LP + G C ++GWG+ Sbjct: 61 SLPRS--CAAAGTECLISGWGNTK 82 >3F1S-B nrPDB Length = 283 Score = 94.2 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 49/245 (20%), Positives = 80/245 (32%), Gaps = 46/245 (18%) Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLL 102 PWQV L FCGG +I +VLT A C + V+ ++ Sbjct: 65 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKC----SLLHRNITVKTYFNRTSQDPLMI 118 Query: 103 PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP---ASETFPPGMPCWVTG 159 ++ + VH ++ D++LLELE P+ V P A P ++G Sbjct: 119 KITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 178 Query: 160 W---GDVDNDERLPPPFPL-------KQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 W G + P L + + V + C+ + D + R+ Sbjct: 179 WARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREH- 237 Query: 210 LCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVV-SWGEGCAQPNRPGIYTRVTYYLDWIH 268 G+W GV+ S G Q + + T+V+ Y W Sbjct: 238 -----------------------RGSWFLTGVLGSQPVG-GQAHMVLV-TKVSRYSLWFK 272 Query: 269 HYVPK 273 + Sbjct: 273 QIMNA 277 >3H5C-B nrPDB Length = 317 Score = 91.6 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 49/244 (20%), Positives = 80/244 (32%), Gaps = 46/244 (18%) Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLL 102 PWQV L FCGG +I +VLT A C + V+ ++ Sbjct: 106 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKC----SLLHRNITVKTYFNRTSQDPLMI 159 Query: 103 PVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP---ASETFPPGMPCWVTG 159 ++ + VH ++ D++LLELE P+ V P A P ++G Sbjct: 160 KITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSG 219 Query: 160 W---GDVDNDERLPPPFPL-------KQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 W G + P L + + V + C+ + D + R+ Sbjct: 220 WARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREH- 278 Query: 210 LCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVV-SWGEGCAQPNRPGIYTRVTYYLDWIH 268 G+W GV+ S G Q + + T+V+ Y W Sbjct: 279 -----------------------RGSWFLTGVLGSQPVG-GQAHMVLV-TKVSRYSLWFK 313 Query: 269 HYVP 272 + Sbjct: 314 QIMN 317 >2KAI-A nrPDB Length = 80 Score = 90.0 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 12/87 (13%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90 I+GG+E ++ PWQV++ + + CGG L++P+WVLTAAHC + V L Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQ---CGGVLVNPKWVLTAAHCKNDN------YEVWL 51 Query: 91 REQHLYYQD---QLLPVSRIIVHPQFY 114 +L+ + Q V+ HP F Sbjct: 52 GRHNLFENENTAQFFGVTADFPHPGFN 78 >2HNT-E nrPDB Length = 81 Score = 82.7 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 99 DQLLPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVTLP---PASETFPPGMP 154 +++ + +I +HP++ + DIAL++L++PV S ++H V LP A+ G Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 155 CWVTGWGDVDND 166 VTGWG++ Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 68.8 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 5/70 (7%) Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDL----AAL 86 IV G +A PWQV L P + CG SLI +WVLTAAHC+ D L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 87 RVQLREQHLY 96 V++ + Sbjct: 60 LVRIGKHSRT 69 >1P3E-A nrPDB Length = 215 Score = 41.9 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 40/110 (36%), Gaps = 7/110 (6%) Query: 54 YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL--REQHLYYQDQLLPVSRIIVHP 111 + C G+LI P +LT HCV + + + + ++ V Sbjct: 27 FGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTEFYVPS 86 Query: 112 QF-YTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGW 160 + T D A+++ + N+ + V ++ T G ++G+ Sbjct: 87 GYINTGASQYDFAVIKTDT--NIGNTVGYRSI--RQVTNLTGTTIKISGY 132 >5ILB-A nrPDB Length = 474 Score = 33.0 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 21/91 (23%) Query: 35 QEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQH 94 AP PWQ + +I +LT AHCV D + ++V+ R Sbjct: 17 HTAPDYSLPWQ-----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQ----VKVKRRGDD 67 Query: 95 LYYQDQLLPVSRIIVHPQFYTAQIGADIALL 125 Y V++++V + DIALL Sbjct: 68 RKY------VAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 33.0 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 21/91 (23%) Query: 35 QEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQH 94 AP PWQ + +I +LT AHCV D + ++V+ R Sbjct: 57 HTAPDYSLPWQ-----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQ----VKVKRRGDD 107 Query: 95 LYYQDQLLPVSRIIVHPQFYTAQIGADIALL 125 Y V++++V + DIALL Sbjct: 108 RKY------VAKVLV------RGVDCDIALL 126 >4JCN-A nrPDB Length = 216 Score = 32.2 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 47 SLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ--LREQHLYYQDQLLPV 104 + + G ++ +LT H V + + V + ++ Y + + Sbjct: 24 FIYIPIDGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVG- 82 Query: 105 SRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP---PASETFPPGMPCWVTGW 160 II +P +D+A+L + P + H+ V P ++ VTG+ Sbjct: 83 QEIIPYPG------NSDLAILRVS-PNEHNQHIGQVVKPATISSNTDTRINENITVTGY 134 >2OUA-A nrPDB Length = 188 Score = 30.7 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 23/72 (31%), Gaps = 11/72 (15%) Query: 189 DAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGC 248 A+ +Y V + +CA GDSGG + GV S G G Sbjct: 115 QARNQTVSYPQGTVHSLTRTSVCAEP-------GDSGGSFI----SGTQAQGVTSGGSGN 163 Query: 249 AQPNRPGIYTRV 260 + Y V Sbjct: 164 CRTGGTTFYQEV 175 >5LAK-A nrPDB Length = 314 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 28/76 (36%), Gaps = 12/76 (15%) Query: 59 CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQI 118 CGG L P+ L HC G D D+ + + +++ + + HP + Sbjct: 153 CGGMLFDPKGRLLGLHCAGSD--DVVFMDTTTGKSNIWTSYK-------LQHPSEIMITL 203 Query: 119 GADIALLELEEPVNVS 134 +I L P N Sbjct: 204 NNEI---NLPNPANYD 216 >2SFA-A nrPDB Length = 191 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 52/200 (26%), Gaps = 48/200 (24%) Query: 65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIAL 124 + LTA HC + + + L T+ G D L Sbjct: 26 GATYALTAGHC----TEIASTWYTNSGQTSLLGTRA-------------GTSFPGNDYGL 68 Query: 125 LELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDV---DNDERLPPPFPLKQVKVP 181 + V G +TG G+ +R L +V Sbjct: 69 IRHSNASAADGRV----------YLYNGSYRDITGAGNAYVGQTVQRSGSTTGLHSGRVT 118 Query: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGV 241 + + GD V + +CA GDSGG L G+ Sbjct: 119 GLNATV-------NYGGGDIVSGLIQTNVCAEP-------GDSGGALFAGS----TALGL 160 Query: 242 VSWGEGCAQPNRPGIYTRVT 261 S G G + + VT Sbjct: 161 TSGGSGNCRTGGTTFFQPVT 180 >2PFE-A nrPDB Length = 186 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 18/43 (41%), Gaps = 6/43 (13%) Query: 212 AGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252 G TR +C GDSGGP + GV S G G + Sbjct: 126 TGLTRTTACAEGGDSGGPWLTGSQ----AQGVTSGGTGDCRSG 164 >4NCX-A nrPDB Length = 506 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%) Query: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTG 159 ++L + +S + + +P PP M C+ +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >3AK5-A nrPDB Length = 975 Score = 28.8 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 10/22 (45%), Gaps = 2/22 (9%) Query: 222 GDSGGPLVCKVN--GTWLQAGV 241 GDSG PL W+ GV Sbjct: 205 GDSGSPLFAFDTVQNKWVLVGV 226 >5OJX-A nrPDB Length = 254 Score = 28.4 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 19/42 (45%) Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERL 169 P +++ +V + F G+ C V+G G + + + L Sbjct: 206 SHPASLADYVKRSASSSTGQRFHDGLECMVSGMGQMRSQDSL 247 >3LT3-A nrPDB Length = 217 Score = 28.4 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 14/27 (51%), Positives = 17/27 (62%), Gaps = 3/27 (11%) Query: 216 RRDSCQGDSGGPLVCKVNGTWLQAGVV 242 R D QGD+GGPL+ +NG GVV Sbjct: 155 RADVEQGDAGGPLI-DLNGQ--VLGVV 178 >2EA3-A nrPDB Length = 189 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 20/56 (35%), Gaps = 11/56 (19%) Query: 197 YTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252 Y VR + +CA GDSGG L+ GV S G G + Sbjct: 117 YPEGTVRGLIRTTVCAEP-------GDSGGSLLAGNQ----AQGVTSGGSGNCRTG 161 >6F07-A nrPDB Length = 620 Score = 26.8 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 2/35 (5%) Query: 95 LYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEE 129 L+ + QLL HP F + DI ++EL+ Sbjct: 520 LWDKVQLLDSGDSFYHPVF--KILQNDIKIIELKN 552 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.145 0.503 Lambda K H 0.267 0.0448 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,677,358 Number of Sequences: 36641 Number of extensions: 556139 Number of successful extensions: 2789 Number of sequences better than 10.0: 179 Number of HSP's better than 10.0 without gapping: 319 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 1079 Number of HSP's gapped (non-prelim): 348 length of query: 275 length of database: 10,336,785 effective HSP length: 96 effective length of query: 179 effective length of database: 6,819,249 effective search space: 1220645571 effective search space used: 1220645571 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.2 bits)