BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20160 (251 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AE5-A nrPDB 459 e-130 1FUJ-A nrPDB 185 2e-47 1PPF-E nrPDB 180 5e-46 4Q7Y-A nrPDB 134 3e-32 3RP2-A nrPDB 132 2e-31 1FDP-A nrPDB 127 6e-30 3G01-A nrPDB 125 1e-29 2ZKS-A nrPDB 125 1e-29 1ORF-A nrPDB 125 1e-29 5FCR-A nrPDB 125 2e-29 1EUF-A nrPDB 125 2e-29 1FI8-A nrPDB 124 3e-29 1MZD-A nrPDB 119 1e-27 3TK9-A nrPDB 117 6e-27 1A0J-A nrPDB 115 2e-26 1IAU-A nrPDB 115 2e-26 3QUM-P nrPDB 115 3e-26 5MS3-A nrPDB 114 3e-26 1KYN-A nrPDB 113 7e-26 2RDL-A nrPDB 111 2e-25 1UTJ-A nrPDB 111 4e-25 2TLD-E nrPDB 109 9e-25 4AN7-A nrPDB 109 1e-24 1NPM-A nrPDB 109 1e-24 4NFE-A nrPDB 109 1e-24 5FXL-A nrPDB 109 1e-24 1NN6-A nrPDB 107 7e-24 1F7Z-A nrPDB 106 1e-23 1ELT-A nrPDB 105 2e-23 1AZZ-A nrPDB 105 3e-23 1SGF-G nrPDB 104 4e-23 2R0L-A nrPDB 103 5e-23 1YC0-A nrPDB 103 7e-23 2BDH-A nrPDB 103 9e-23 3BSQ-A nrPDB 102 1e-22 1TON-A nrPDB 100 9e-22 1BRU-P nrPDB 99 1e-21 5C67-A nrPDB 99 2e-21 1EQ9-A nrPDB 99 2e-21 1GVZ-A nrPDB 99 2e-21 3S9B-A nrPDB 98 3e-21 3W94-A nrPDB 98 3e-21 4WWY-A nrPDB 98 3e-21 5UGG-A nrPDB 97 5e-21 5ZFH-A nrPDB 97 8e-21 1SPJ-A nrPDB 96 1e-20 4GSO-A nrPDB 95 3e-20 1SGF-A nrPDB 95 3e-20 2EEK-A nrPDB 94 5e-20 6QHB-A nrPDB 94 5e-20 1AO5-A nrPDB 94 6e-20 4DUR-A nrPDB 94 7e-20 2PSX-A nrPDB 94 8e-20 2ASU-B nrPDB 94 8e-20 2AIQ-A nrPDB 94 8e-20 3T2N-A nrPDB 93 9e-20 4MPW-A nrPDB 93 1e-19 1P57-B nrPDB 93 1e-19 1YM0-A nrPDB 92 1e-19 1SI5-H nrPDB 92 2e-19 3DFJ-A nrPDB 92 2e-19 1LTO-A nrPDB 91 4e-19 3F6U-H nrPDB 91 5e-19 4XDE-A nrPDB 90 9e-19 3E0N-B nrPDB 90 1e-18 5TJX-A nrPDB 89 1e-18 4DGJ-A nrPDB 89 2e-18 5GVT-A nrPDB 88 3e-18 1OP0-A nrPDB 88 4e-18 2CGA-A nrPDB 88 4e-18 4LK4-A nrPDB 87 8e-18 1A5I-A nrPDB 87 8e-18 1X7A-C nrPDB 86 1e-17 3P8G-A nrPDB 86 1e-17 1EKB-B nrPDB 86 1e-17 1FON-A nrPDB 86 2e-17 4E7N-A nrPDB 86 2e-17 2PKA-B nrPDB 86 2e-17 6I44-A nrPDB 84 5e-17 2F91-A nrPDB 84 8e-17 4H4F-A nrPDB 83 1e-16 5XRF-A nrPDB 81 3e-16 3S69-A nrPDB 81 5e-16 2V35-A nrPDB 80 6e-16 5LPF-A nrPDB 79 1e-15 3LC3-A nrPDB 79 2e-15 2OQ5-A nrPDB 79 2e-15 2B9L-A nrPDB 79 2e-15 1PYT-D nrPDB 79 3e-15 1BDA-A nrPDB 78 4e-15 3VGC-B nrPDB 77 5e-15 1BQY-A nrPDB 77 7e-15 1M9U-A nrPDB 76 1e-14 6AOD-C nrPDB 76 1e-14 2OLG-A nrPDB 75 2e-14 1FXY-A nrPDB 75 2e-14 2F83-A nrPDB 74 4e-14 5XW8-A nrPDB 74 4e-14 1FIZ-A nrPDB 74 4e-14 6BQM-A nrPDB 74 5e-14 4FXG-H nrPDB 73 9e-14 1ZJK-A nrPDB 73 1e-13 1Q3X-A nrPDB 73 1e-13 1PQ7-A nrPDB 71 4e-13 5KWM-A nrPDB 71 4e-13 2JET-B nrPDB 69 1e-12 3I77-A nrPDB 69 2e-12 1KIG-H nrPDB 69 2e-12 1FIW-A nrPDB 68 3e-12 4DJZ-B nrPDB 68 3e-12 4IGD-A nrPDB 67 5e-12 3BEU-A nrPDB 66 1e-11 5LHN-A nrPDB 65 2e-11 2QY0-B nrPDB 65 2e-11 1SC8-U nrPDB 65 3e-11 1ETT-H nrPDB 65 3e-11 1MKW-K nrPDB 65 4e-11 1MD7-A nrPDB 64 4e-11 3H7O-A nrPDB 64 4e-11 2XXL-A nrPDB 64 6e-11 1GPZ-A nrPDB 63 1e-10 2HLC-A nrPDB 63 1e-10 5O32-I nrPDB 62 2e-10 4Z6A-H nrPDB 62 2e-10 3H7T-A nrPDB 62 3e-10 2XRC-A nrPDB 61 5e-10 2FMJ-A nrPDB 60 9e-10 2OCV-B nrPDB 59 2e-09 1C5M-D nrPDB 59 2e-09 4KKD-A nrPDB 58 4e-09 4IW4-E nrPDB 57 6e-09 3K65-B nrPDB 57 7e-09 3NXP-A nrPDB 56 1e-08 4NZQ-A nrPDB 55 2e-08 1VR1-H nrPDB 55 3e-08 5TO3-B nrPDB 53 1e-07 4BXW-A nrPDB 49 1e-06 1BBR-H nrPDB 49 2e-06 5UBM-A nrPDB 46 1e-05 1ELV-A nrPDB 46 2e-05 4J1Y-A nrPDB 43 1e-04 1AKS-B nrPDB 42 3e-04 1RIW-B nrPDB 40 7e-04 1EPT-B nrPDB 39 0.002 2KAI-A nrPDB 38 0.004 3F1S-B nrPDB 38 0.004 3H5C-B nrPDB 38 0.004 4F4O-C nrPDB 37 0.011 2OK5-A nrPDB 35 0.028 1DLE-A nrPDB 35 0.042 2WIN-I nrPDB 34 0.057 2I6S-A nrPDB 33 0.088 2JET-C nrPDB 32 0.32 1BBR-E nrPDB 30 0.97 2HNT-F nrPDB 30 1.3 1UP3-A nrPDB 28 2.6 3RU4-E nrPDB 28 2.8 5F2K-A nrPDB 27 7.5 5EJ2-A nrPDB 27 9.9 >1AE5-A nrPDB Length = 225 Score = 459 bits (1182), Expect = e-130, Method: Compositional matrix adjust. Identities = 225/225 (100%), Positives = 225/225 (100%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 206 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 180 Query: 207 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA 251 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA Sbjct: 181 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA 225 >1FUJ-A nrPDB Length = 221 Score = 185 bits (470), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 99/222 (44%), Positives = 139/222 (62%), Gaps = 7/222 (3%) Query: 27 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG +A+P P++AS+Q N G HFCGG LIH FV+TAA C + + VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++R +E ++Q FS++ + N YD + LND++L+QL ANL++SV + LP Q+ V Sbjct: 61 HNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGT 203 GT+C GWG + ++ + +NVTV CRP+N+CT V R+ GIC GD G Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHNICTFVPRRKAGICFGDSGG 178 Query: 204 PLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 PL+C+G+ G+ SF + C PDFFTRVAL+ DWI L Sbjct: 179 PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 220 >1PPF-E nrPDB Length = 218 Score = 180 bits (457), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 100/219 (45%), Positives = 135/219 (61%), Gaps = 4/219 (1%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGR+ARP +PF+ S+Q +G HFCG LI FVM+AA C + N VVLGA++L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 RRE +RQ F++ + ENGYDP LND+++LQL+ A + ++V + LP Q + G Sbjct: 61 SRRE-PTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 119 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 206 +C GWG ++ + +NVTV CR +NVCT V R+ G+C GD G+PLV Sbjct: 120 VQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSNVCTLVRGRQAGVCFGDSGSPLV 178 Query: 207 CEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 243 C GL HG+ASF G C G PD F VA F +WID ++ Sbjct: 179 CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 217 >4Q7Y-A nrPDB Length = 250 Score = 134 bits (337), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 92/241 (38%), Positives = 130/241 (53%), Gaps = 20/241 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P++AS++ G+H CGG L+ AR+V++AA CF ++ VVLGA+ L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 87 RRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA-TVE 144 E ++Q F I +++ + Y P + ND+ LL+L+ A L +V +L LP + A Sbjct: 61 STAE-PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPT 119 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLT-----------RR 193 AGTRC+VAGWG L V V D C N+ G LT R Sbjct: 120 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVC--NSSWKGHLTLTMLCTRSGDSHR 177 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL--NNPGPG 249 G C+ D G PLVC AHG+ SFS CG + PD +T+V+ F WI V+ ++P PG Sbjct: 178 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 237 Query: 250 P 250 P Sbjct: 238 P 238 >3RP2-A nrPDB Length = 224 Score = 132 bits (332), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 78/229 (34%), Positives = 118/229 (51%), Gaps = 16/229 (6%) Query: 27 IVGGRKARPRQFPFLAS---IQNQG-RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG ++ P P++A + +G R CGG LI +FV+TAA C + TV+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGRE----ITVILG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A+D+R+RE ++ + Y+ NL+D+MLL+L+++ LT +V ++PLP + Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------RPNNVCTGVLTRRGG 195 + G C AGWG S R V + + E C VC G T Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 GD G PL+C G+AHG+ S+ P + P FTRV+ + WI+ V+N Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSYG-HPDAKPPAIFTRVSTYVPWINAVIN 224 >1FDP-A nrPDB Length = 235 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 79/227 (34%), Positives = 109/227 (48%), Gaps = 10/227 (4%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GGR+A P++AS+Q G H CGG L+ ++V++AA C + G V+LGA+ L Sbjct: 8 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSL 67 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 + E R + ++ P +DL+LLQL +A L +V LP + V G Sbjct: 68 SQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG 127 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTR--------RGGICN 198 T C VAGWG GR + V + V C G +T R C Sbjct: 128 TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCK 187 Query: 199 GDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 GD G PLVC G+ GV + CG + P +TRVA + WID VL Sbjct: 188 GDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >3G01-A nrPDB Length = 227 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 112/233 (48%), Gaps = 20/233 (8%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVL 81 I+GG + P P++A + + FCGG L+ +FV+TAA C G S TV L Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC-----KGRSMTVTL 55 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 GA++++ +E + ++ Y+P ND+MLL+L R A T +V L LP +NA Sbjct: 56 GAHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNA 115 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTR 192 V+ G C VAGWG G + V +TV + C R N +C G Sbjct: 116 HVKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKI 175 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 +G GD G PLVC+ A G+ S+ G P FTRV F WI + + Sbjct: 176 KGASFRGDSGGPLVCKRAAAGIVSYGQTD-GSAPQVFTRVLSFVSWIKKTMKH 227 >2ZKS-A nrPDB Length = 240 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 86/232 (37%), Positives = 115/232 (49%), Gaps = 21/232 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GGR+ P P++AS+Q G H CGG L+H ++V+TAA C +Q +VLG + L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL-AQRMAQLRLVLGLHTL 59 Query: 87 RRRERQSRQTFSI-SSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILPLPLQNATVE 144 TF I +++ Y P L NDL LLQLD + + ++ L LP + V Sbjct: 60 D----SPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVA 115 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----------PNNVCTGVLTRRG 194 AGTRC +AGWG GGRLSR R +++ V C P+ VC ++ Sbjct: 116 AGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQ 175 Query: 195 GICNGDGGTPLVCEG--LAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGV 242 C GD G PLVC + GV SFS C P T VA + WI V Sbjct: 176 APCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 227 >1ORF-A nrPDB Length = 234 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/231 (35%), Positives = 111/231 (48%), Gaps = 23/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P++ + + C GALI +V+TAA C ++ S V+LGA+ + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHSI 57 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E + YDP DL LLQL +A + VTIL LP + V+ G Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN------------VCTGVLTRRG 194 T CQVAGWG + S R V +T+ C N VC G L RG Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RG 175 Query: 195 G--ICNGDGGTPLVCEGLAHGVASFSL-GPCG--RGPDFFTRVALFR-DWI 239 G CNGD G+PL+CEG+ GV SF L CG RGP + ++ +WI Sbjct: 176 GRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 226 >5FCR-A nrPDB Length = 234 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 78/229 (34%), Positives = 111/229 (48%), Gaps = 11/229 (4%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVST-VVLGAYD 85 I+GG++A P++AS+Q G H CGG L+ ++V++AA C S V+LGA+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L E R S + G P +DL+L +L + A+L V LPL ++ VE Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLT--------RRGGIC 197 GT C VAGWG GR + V++ C GV+T R C Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTC 180 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 GD G+PLVC GV ++ CG G P +TRV+ +R WI+ + N Sbjct: 181 RGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITN 229 >1EUF-A nrPDB Length = 227 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 79/230 (34%), Positives = 121/230 (52%), Gaps = 20/230 (8%) Query: 27 IVGGRKARPRQFPFLASI--QNQGR-HFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A + + G+ H CGG L+ FV+TAA C S V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSS----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++ RER + + Y+ + ND+MLL+L R+A++T V+ + LP A V Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRF--VNVTVTPEDQC--RPNN------VCTGVLTRR 193 + G C VAGWG R G + + V++ V E++C R N +C G ++R Sbjct: 117 KPGMMCSVAGWG--RLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKR 174 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVL 243 +GD G PLVC G+A G+ S+ G PD +TR++ F WI + Sbjct: 175 KNSFSGDSGGPLVCNGVAQGIVSYGRND-GTTPDVYTRISSFLSWIHSTM 223 >1FI8-A nrPDB Length = 228 Score = 124 bits (311), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 18/232 (7%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG +A+P P++A +Q G CGG LI FV+TAA C S+ V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK----IQVTLG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A++++ +E+ + + + Y+ + ND+MLL+L +A +S+V L LP +N Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRR 193 V+ G C VAGWG G+ S + V +TV + +C + N +C G + Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G PLVC+ +A G+ S+ G P FT+V+ F WI + Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYGQND-GSTPRAFTKVSTFLSWIKKTMKK 227 >1MZD-A nrPDB Length = 240 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 85/242 (35%), Positives = 118/242 (48%), Gaps = 25/242 (10%) Query: 25 LDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGA 83 ++I+GG++ P PF+ASIQ G H CGG LI ++V+TAA C G S TVVLGA Sbjct: 1 MEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGA 60 Query: 84 YDLRRRERQSRQTFSISS---MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + L + E S+QT I S DPQ ND+ML++L A L V +L + Sbjct: 61 HSLSKNE-ASKQTLEIKKFIPFSRVTSDPQS--NDIMLVKLQTAAKLNKHVKMLHI-RSK 116 Query: 141 ATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPNN------------VCT 187 ++ +GT+C+V GWG+ R S R V VTV C + VC Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 188 GVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVA-LFRDWIDGVLN 244 G + C GD G PL+C+G+ H + S CG P +T + ++ WI L Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHAIVSGG-HECGVATKPGIYTLLTKKYQTWIKSNLV 235 Query: 245 NP 246 P Sbjct: 236 PP 237 >3TK9-A nrPDB Length = 226 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 76/230 (33%), Positives = 117/230 (50%), Gaps = 18/230 (7%) Query: 27 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A +Q + R CGG L+ FV+TAA C Q ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC---QGSSIN-VTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++ +ER + + Y+P+ N++MLLQL+R+A T++V L LP A V Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRRG 194 + G C VAGWG S L+ + V +TV + QC R +C G + Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 GD G PLVC+ +A G+ S+ G P + +V+ F WI + Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYG-NKKGTPPGVYIKVSHFLPWIKRTMK 224 >1A0J-A nrPDB Length = 223 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 73/231 (31%), Positives = 119/231 (51%), Gaps = 21/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + R + AS+Q+ G HFCGG+LI + +V++AA C++S+ V LG +++ Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHCYKSR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + S+ + Y+ + ND+ML++L + A+L S V+ + LP ++ +G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALP--SSCASSG 113 Query: 147 TRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCRP--------NNVCTGVLTRRGG 195 TRC V+GWG+ G S +P R +++ + C N C G + Sbjct: 114 TRCLVSGWGNLS--GSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKD 171 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVLNN 245 C GD G P+VC G GV S+ G R P +T+V +R WI +++ Sbjct: 172 SCQGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSS 222 >1IAU-A nrPDB Length = 227 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 111/230 (48%), Gaps = 17/230 (7%) Query: 27 IVGGRKARPRQFPFLASI---QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A + + CGG LI FV+TAA C+ S V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++ +E + + Y+P+ ND+MLLQL+R+A T +V L LP A V Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTRRG 194 + G C VAGWG G+ S + V +TV + +C + +C G + Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 GD G PLVC +A G+ S+ G P T+V+ F WI + Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSYGRN-NGMPPRACTKVSSFVHWIKKTMK 225 >3QUM-P nrPDB Length = 237 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 119/244 (48%), Gaps = 31/244 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ + ++GR CGG L+H ++V+TAA C +++ S ++LG + L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 56 Query: 87 RRRERQSRQTFSIS-SMSENGYDP-----------QQNLNDLMLLQLDREANLTSSVTIL 134 E + Q F +S S YD + +DLMLL+L A LT +V ++ Sbjct: 57 FHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 115 Query: 135 PLPLQNATVEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTVTPEDQC---RPNNV----- 185 LP Q + GT C +GWGS L+ + + V++ V D C P V Sbjct: 116 DLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 173 Query: 186 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWI-DGV 242 C G T C+GD G PLVC G+ G+ S+ PC P +T+V +R WI D + Sbjct: 174 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 Query: 243 LNNP 246 + NP Sbjct: 234 VANP 237 >5MS3-A nrPDB Length = 228 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 121/236 (51%), Gaps = 23/236 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + +P P+ A++ + CGG L+ +V+TAA C + + TV LG + L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK----YTVRLGDHSL 56 Query: 87 RRRERQSRQTFSISSMSE---NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + ++ ++ + S+ N D + + +DLMLLQL +A+L S V P+ L + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVK--PISLADHCT 114 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQCR---PNNVCTGVL----TRR 193 + G +C V+GWG+ S FP +N V + P+ +C P + G++ ++ Sbjct: 115 QPGQKCTVSGWGTVTS--PRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG 172 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNNPG 247 C GD G PLVC+G G+ S+ PCGR P +T + + DWI ++ + G Sbjct: 173 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 228 >1KYN-A nrPDB Length = 235 Score = 113 bits (283), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 79/226 (34%), Positives = 113/226 (50%), Gaps = 21/226 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GGR++RP P++A +Q Q G+ CGG L+ FV+TAA C+ S V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++RRE + + ++ Y+ + ND+MLLQL R +V + LP + Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 144 EAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRR 193 GT C VAGWG S R G + R V + V + QC +C G R Sbjct: 117 RPGTLCTVAGWGRVSMRRG---TDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRER 173 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 GD G PL+C +AHG+ S+ G P+ FTRV+ F WI Sbjct: 174 KAAFKGDSGGPLLCNNVAHGIVSYG-KSSGVPPEVFTRVSSFLPWI 218 >2RDL-A nrPDB Length = 226 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 71/228 (31%), Positives = 111/228 (48%), Gaps = 16/228 (7%) Query: 27 IVGGRKARPRQFPFLASIQ--NQGRHF--CGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG + RP P++A ++ H C G LI FVMTAA C TV+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRS----ITVLLG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A++ + +E ++ YD + LND+MLL+L +ANLT V LP+ ++ + Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNS 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------PNNVCTGVLTRRGG 195 + G C+ GWG S + V + + C+ +C G + Sbjct: 117 IPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRN 176 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVL 243 + GD G PL+C G+A G+AS+ L + P FTR++ +R WI+ +L Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVLR-NAKPPSVFTRISHYRPWINKIL 223 >1UTJ-A nrPDB Length = 242 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 69/226 (30%), Positives = 108/226 (47%), Gaps = 16/226 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + +P P S+ N G HFCGG+L++ +V++AA C++S+ V LG +++ Sbjct: 21 IVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNENWVVSAAHCYKSR----VEVRLGEHNI 75 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 + E + S + Y ND+ML++L + A L + V P+ L + AG Sbjct: 76 KVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQ--PVALPTSCAPAG 133 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN--------VCTGVLTRRGGICN 198 T C V+GWG+ S S + +N+ + C + C G L C Sbjct: 134 TMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYLEGGKDSCQ 193 Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 GD G P+VC G GV S+ G G P + +V +F DW+ + Sbjct: 194 GDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFNDWLTSTM 239 >2TLD-E nrPDB Length = 220 Score = 109 bits (273), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 71/224 (31%), Positives = 112/224 (50%), Gaps = 22/224 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S G+ V LG ++ Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKS---GIQ-VRLGEDNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + S+ Y+ ND+ML++L A+L S V + LP A+ AG Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--AG 113 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTP---EDQCRP--------NNVCTGVLTRRGG 195 T+C ++GWG+ +S G + +P + P + C+ N C G+ G Sbjct: 114 TQCLISGWGNTKSSG--TSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGL--EGGD 169 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 C GD G P+VC G G+ S+ G P +T+V + WI Sbjct: 170 SCQGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWI 213 >4AN7-A nrPDB Length = 231 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 69/225 (30%), Positives = 111/225 (49%), Gaps = 21/225 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S+ V LG +++ Sbjct: 9 IVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGEHNI 63 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + ++ ++ ND+ML++L A L S V + LP A AG Sbjct: 64 DVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAA--AG 121 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTP---EDQCRP--------NNVCTGVLTRRGG 195 T C ++GWG+ +S G S +P + P + C+ N +C G L Sbjct: 122 TECLISGWGNTKSSG--SSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKD 179 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWI 239 C GD G P+VC G G+ S+ G + P +T+V + +WI Sbjct: 180 SCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWI 224 >1NPM-A nrPDB Length = 225 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 69/233 (29%), Positives = 118/233 (50%), Gaps = 23/233 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ GR+ P P+ A++ R CGG L+ R+V+TAA C + + +V LG + L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQK----YSVRLGDHSL 56 Query: 87 RRR---ERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + R E++ + SI N +P+ + +D+ML++L ANL V P+ L N Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVK--PVQLANLCP 114 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQCR---PNNVCTGVL----TRR 193 + G +C ++GWG+ S FP +N V + +++C P + G++ + Sbjct: 115 KVGQKCIISGWGTVTS--PQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNG 172 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLN 244 C GD G PLVC+G+ G+ S+ PCG+ P +T++ + WI ++ Sbjct: 173 ADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMD 225 >4NFE-A nrPDB Length = 237 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 113/243 (46%), Gaps = 29/243 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ ++ + G CGG L+H ++V+TAA C + S V LG ++L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN----SQVWLGRHNL 56 Query: 87 RRRERQSRQT----------FSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILP 135 E ++ +++S + P ++ +DLMLL+L A +T V +L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNVC 186 LP Q + GT C +GWGS L R + V++ + D C +C Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWI-DGVL 243 G+ T C GD G PLVC G+ G+ S+ PC P +T+V +R WI D + Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 234 Query: 244 NNP 246 NP Sbjct: 235 ANP 237 >5FXL-A nrPDB Length = 246 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 122/254 (48%), Gaps = 30/254 (11%) Query: 1 MTRLTVLALLAGLLASSRAGSSPLLD---IVGGRKARPRQFPFLASIQNQGRHFCGGALI 57 M LALL +A P+ D IVGG P+ S+ N G HFCGG+LI Sbjct: 1 MKTFIFLALLGAAVAF------PVDDDDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLI 53 Query: 58 HARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLM 117 ++++V++AA C++S G+ V LG ++ E + + S+ Y+ ND+M Sbjct: 54 NSQWVVSAAHCYKS---GIQ-VRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIM 109 Query: 118 LLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP- 176 L++L A+L S V + LP A+ AGT+C ++GWG+ +S G + +P + P Sbjct: 110 LIKLKSAASLNSRVASISLPTSCAS--AGTQCLISGWGNTKSSG--TSYPDVLKCLKAPI 165 Query: 177 --EDQCR--------PNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG- 225 + C+ N C G L C GD G P+VC G G+ S+ G + Sbjct: 166 LSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNK 225 Query: 226 PDFFTRVALFRDWI 239 P +T+V + WI Sbjct: 226 PGVYTKVCNYVSWI 239 >1NN6-A nrPDB Length = 228 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 73/230 (31%), Positives = 110/230 (47%), Gaps = 18/230 (7%) Query: 26 DIVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVV 80 +I+GG + +P P++A ++ N FCGG LI FV+TAA C G S TV Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITVT 56 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 LGA+++ E ++ I Y+ +D+MLL+L +A+LT +V LP P Q Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------RPNNVCTGVLTRR 193 V G C+VAGWG S + V + + C +C G + Sbjct: 117 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKT 176 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVL 243 GD G PL+C G+A G+ S+ + P FTR++ +R WI+ +L Sbjct: 177 KSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKPPAVFTRISHYRPWINQIL 225 >1F7Z-A nrPDB Length = 233 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 68/224 (30%), Positives = 110/224 (49%), Gaps = 19/224 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ S+ N G HFCGG+LI+ ++V++AA C++S+ V LG +++ Sbjct: 11 IVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKSR----IQVRLGEHNI 65 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + + +D + ND+ML++L L + V + LP ++ AG Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALP--SSCAPAG 123 Query: 147 TRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGIC 197 T+C ++GWG+ S G + ++ + P+ C N VC G L C Sbjct: 124 TQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSC 183 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWI 239 GD G P+VC G G+ S+ G C P +T+V + DWI Sbjct: 184 QGDSGGPVVCNGELQGIVSWGYG-CALPDNPGVYTKVCNYVDWI 226 >1ELT-A nrPDB Length = 236 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 113/240 (47%), Gaps = 27/240 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQG----RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGGR A+P +P+ S+Q + H CGG+LI +VMTAA C S VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSAR--TWRVVLG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGY--DPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 ++L E + + S +G+ D D+ LL+L+ +A+L S+V + LP N Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLS------RFPRFVNVTVTPE----DQCRPNNVCTGVL 190 + C + GWG +GG LS P + T + + VC G Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGG 178 Query: 191 TRRGGICNGDGGTPLVCE----GLAHGVASF-SLGPC--GRGPDFFTRVALFRDWIDGVL 243 G CNGD G PL C+ HGV SF S C + P FTRV+ + W++G++ Sbjct: 179 ANSG--CNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >1AZZ-A nrPDB Length = 226 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 75/223 (33%), Positives = 104/223 (46%), Gaps = 15/223 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG +A P +P A++ +FCGG+LI +++TAA C G VVLGA+++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGA--GFVDVVLGAHNI 58 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E S Y+ ND+ +++L LT+++ + LP + V G Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD--VGVG 116 Query: 147 TRCQVAGWG-SQRSGGRLSRFPRFVNVTVTPEDQCRP-------NNVCTGVLTRRGGICN 198 T GWG S +S R V+V + C N+C T G CN Sbjct: 117 TVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICIDS-TGGKGTCN 175 Query: 199 GDGGTPLVCEGLAHGVASF-SLGPCGRG-PDFFTRVALFRDWI 239 GD G PL GL +G+ SF + C G PD FTRV F DWI Sbjct: 176 GDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWI 218 >1SGF-G nrPDB Length = 237 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 112/243 (46%), Gaps = 29/243 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG K P+ ++ ++ CGG L+ +V+TAA C+ V LG +L Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGKNNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREANLTSSVTILP 135 + E ++ F ++ G++ NDLMLL+L + A++T +V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 136 LPLQNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCRPNNV--------C 186 LP + + G+ C +GWGS + + + VN+ + P + C ++ C Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWI-DGVL 243 G + C GD G PL+C+G+ G+ S+ PCG P +T++ F WI D + Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 244 NNP 246 NP Sbjct: 235 KNP 237 >2R0L-A nrPDB Length = 248 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 117/246 (47%), Gaps = 31/246 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P+LA+I G FC G+L+H +V++AA CF P S V+ Sbjct: 1 IIGGSSSLPGSHPWLAAIY-IGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 87 RRRERQSRQTFSISSMS----ENGYDPQQNLNDLMLLQL----DREANLTSSVTILPLPL 138 R QTF I + ++P +DL+L++L DR A + V + LP Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSD--HDLVLIRLKKKGDRCATRSQFVQPICLPE 117 Query: 139 QNATVEAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVC 186 +T AG +CQ+AGWG + G S R V + + +C PN +C Sbjct: 118 PGSTFPAGHKCQIAGWGHLDENVSGYSSSL-REALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 187 TGVLTRRGGICNGDGGTPLVCE--GLA--HGVASFSLGPCGR--GPDFFTRVALFRDWID 240 G + C GD G PL CE G+A +G+ S+ G CGR P +TRVA + DWI+ Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWIN 235 Query: 241 GVLNNP 246 + P Sbjct: 236 DRIRPP 241 >1YC0-A nrPDB Length = 283 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 117/246 (47%), Gaps = 31/246 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P+LA+I G FC G+L+H +V++AA CF P S V+ Sbjct: 36 IIGGSSSLPGSHPWLAAIY-IGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 94 Query: 87 RRRERQSRQTFSISSMS----ENGYDPQQNLNDLMLLQL----DREANLTSSVTILPLPL 138 R QTF I + ++P +DL+L++L DR A + V + LP Sbjct: 95 FNRTTDVTQTFGIEKYIPYTLYSVFNPSD--HDLVLIRLKKKGDRCATRSQFVQPICLPE 152 Query: 139 QNATVEAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVC 186 +T AG +CQ+AGWG + G S R V + + +C PN +C Sbjct: 153 PGSTFPAGHKCQIAGWGHLDENVSGYSSSL-REALVPLVADHKCSSPEVYGADISPNMLC 211 Query: 187 TGVLTRRGGICNGDGGTPLVCE--GLA--HGVASFSLGPCGR--GPDFFTRVALFRDWID 240 G + C GD G PL CE G+A +G+ S+ G CGR P +TRVA + DWI+ Sbjct: 212 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWIN 270 Query: 241 GVLNNP 246 + P Sbjct: 271 DRIRPP 276 >2BDH-A nrPDB Length = 223 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 18/225 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G P P+ A++ + FC G L+H ++V++AA CFQ+ T+ LG + L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHSL 56 Query: 87 RRRERQSRQTFSIS-SMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + Q S S+ Y+ NDLML++LD +++ S TI + + + A Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDE--SVSESDTIRSISIASQCPTA 114 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 197 G C V+GWG + GR+ + VNV+V E+ C P+ C G + C Sbjct: 115 GNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWID 240 NGD G PL+C G G+ SF PCG+ P +T + F +WI+ Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 218 >3BSQ-A nrPDB Length = 227 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 117/231 (50%), Gaps = 23/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G P+ ++ + + CGG L++ R+V+TAA C ++ TV LG+ L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE----YTVHLGSDTL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 +R++++ + S GY Q ++NDLML++L+ +A L+S V + LP + G Sbjct: 57 G--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPPG 112 Query: 147 TRCQVAGWGSQRSGGRLSRFPR---FVNVT-VTPEDQCRPNN-------VCTGVLTRRGG 195 T C V+GWG+ S FP V+V ++P+D + +C G+ + Sbjct: 113 TTCTVSGWGTTTSPD--VTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 170 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLN 244 CNGD G PLVC G G+ S+ PCG+ P +T+V F WI+ + Sbjct: 171 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1TON-A nrPDB Length = 235 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 72/243 (29%), Positives = 112/243 (46%), Gaps = 31/243 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG K P+ ++ N+ + CGG LI +V+TAA C+ + V+LG +L Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCYSNN----YQVLLGRNNL 54 Query: 87 RRRERQSRQTFSISSMSENGYDP-----------QQNLNDLMLLQLDREANLTSSVTILP 135 + E +++ S Y P + NDLMLL L A++T V ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 136 LPLQNATVEAGTRCQVAGWGSQR-SGGRLSRFPRFVNVTVTPEDQC---RPNNV-----C 186 LP + V G+ C +GWGS S +S + VN+ + ++C +NV C Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL- 243 G + C GD G PL+C+G+ G+ S PC + P + ++ F WI V+ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 244 NNP 246 NP Sbjct: 233 ENP 235 >1BRU-P nrPDB Length = 241 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/247 (31%), Positives = 110/247 (44%), Gaps = 35/247 (14%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG ARP +P+ S+Q Q RH CGG L+ +V+TAA C S VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSR--TYRVVLG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQ--NLNDLMLLQLDREANLTSSVTILPLPLQN 140 + L E S + ++ Q N ND+ LL+L +LT + + LP Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCT--- 187 + C V GWG ++ G + + V C + N +C Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGD 178 Query: 188 GVLTRRGGICNGDGGTPLVCEGL-----AHGVASF--SLGPCG--RGPDFFTRVALFRDW 238 G+++ CNGD G PL C+G HG+ SF SLG C P FTRV+ + DW Sbjct: 179 GIISS----CNGDSGGPLNCQGANGQWQVHGIVSFGSSLG-CNYYHKPSVFTRVSNYIDW 233 Query: 239 IDGVLNN 245 I+ V+ N Sbjct: 234 INSVIAN 240 >5C67-A nrPDB Length = 224 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 67/229 (29%), Positives = 112/229 (48%), Gaps = 21/229 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI ++V++AA C++++ V LG +++ Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYKTR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 + E + + + Y+ ND+ML++L A + + V+ + LP A AG Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP--TAPPAAG 113 Query: 147 TRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCR---PNNV-----CTGVLTRRGG 195 T C ++GWG+ S G + +P + ++ V + +C+ P + C G L Sbjct: 114 TECLISGWGNTLSFG--ADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKD 171 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 C D G P+VC G GV S+ G + P +T+V + DWI + Sbjct: 172 SCQRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >1EQ9-A nrPDB Length = 222 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/228 (32%), Positives = 107/228 (46%), Gaps = 19/228 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG+ A ++P+ S++ G H CG +++ V+TAA C N V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 86 LRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 L +S + + N YD ND+ L+ L V + L + +E Sbjct: 61 LS----ESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------PNNVCTGVLTRRG-GI 196 + C + GWGS R GG + + + V P+ QC +++CT LT+RG G Sbjct: 117 SNP-CTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICT--LTKRGEGA 173 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 C+GD G PLV G G+ SF PC G PD +TRV+ F WI+ L Sbjct: 174 CHGDSGGPLVANGAQIGIVSFG-SPCALGEPDVYTRVSSFVSWINANL 220 >1GVZ-A nrPDB Length = 237 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 114/249 (45%), Gaps = 44/249 (17%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P+ ++ +QG CGG L+H ++V+TAA C + LG ++L Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDD----YQIWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNL---------------NDLMLLQLDREANLTSSV 131 + E T +S++ DPQ +L +DLMLL+L + A +T +V Sbjct: 57 SKDE----DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAV 112 Query: 132 TILPLPLQNATVEAGTRCQVAGWG-----SQRSGGRLSRFPRFVNVTVTPEDQC---RPN 183 IL LP Q + G+ C +GWG + R G L + V + + ++C P Sbjct: 113 KILDLPTQEPKL--GSTCYTSGWGLISTFTNRGSGTL----QCVELRLQSNEKCARAYPE 166 Query: 184 NVCTGVL--TRR---GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFR 236 + VL T R G IC GD G L+C+G+ G+ S+ C D FT+V + Sbjct: 167 KMTEFVLCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHK 226 Query: 237 DWIDGVLNN 245 WI + Sbjct: 227 KWIKETIEK 235 >3S9B-A nrPDB Length = 234 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 67/236 (28%), Positives = 111/236 (47%), Gaps = 31/236 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH--FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 +VGG + + PFL ++ C GALI+ +V+TAA C + + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRN----IRIKLGMH 56 Query: 85 --DLRRRERQSR----QTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL 138 ++R + Q R + F +++ NG D D+ML++L R +T S I P+ L Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLD-----KDIMLIRLRRP--VTYSTHIAPVSL 109 Query: 139 QNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGV 189 + + G+RC++ GWG + S P N+ + C P +C G+ Sbjct: 110 PSRSRGVGSRCRIMGWG-KISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGI 168 Query: 190 LTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 L C+GD G PL+C G HG+ + PCG+ P +T+V + +WI ++ Sbjct: 169 LKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >3W94-A nrPDB Length = 235 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 112/235 (47%), Gaps = 27/235 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS--TVVLGAY 84 +VGG A +P++ S+ +GRH CG +LI +++TAA C +N + + VLG + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 85 ---DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 + +E Q RQ I + Y+ + D+ ++ L + N T V + L ++ Sbjct: 61 AQSSMNSQEVQIRQVDRI--IINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQ 118 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTR 192 AG RC +AGWG GG L + V + +D+C+ + +C G Sbjct: 119 HFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGY--P 176 Query: 193 RGGI--CNGDGGTPLVCEGLAH----GVASFSLGPCGR--GPDFFTRVALFRDWI 239 GG+ C GD G PL+C A GV SF +G CGR P + RV+ F WI Sbjct: 177 EGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVG-CGRPERPGAYARVSAFTSWI 230 >4WWY-A nrPDB Length = 224 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 21/229 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI+ ++V++A C++S+ V LG +++ Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + + YD + ND+ML++L A + + V+ + LP A G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLP--TAPPATG 113 Query: 147 TRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCRP--------NNVCTGVLTRRGG 195 T+C ++GWG+ S G + +P + ++ V + +C N C G L Sbjct: 114 TKCLISGWGNTASSG--ADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKD 171 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 C D G P+VC G GV S+ G + P +T+V + WI + Sbjct: 172 SCQRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >5UGG-A nrPDB Length = 251 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 76/236 (32%), Positives = 112/236 (47%), Gaps = 24/236 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQ-SQNPGVSTVVLGAY 84 +VGG A P +P+ S++ + G HFCGG LI +V+TAA C + S P V+LGA+ Sbjct: 22 VVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAH 81 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 E ++ +S +P + D+ LL+L A +T V LP N V Sbjct: 82 QEVNLEPHVQEI----EVSRLFLEPTR--KDIALLKLSSPAVITDKVIPACLPSPNYVVA 135 Query: 145 AGTRCQVAGWG-SQRSGG----RLSRFPRFVNVTVTPED----QCRPNNVCTGVLTRRGG 195 T C + GWG +Q + G + ++ P N + + + +C G L Sbjct: 136 DRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTD 195 Query: 196 ICNGDGGTPLVC----EGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 C GD G PLVC + + GV S+ LG C R P + RV+ F WI+GV+ N Sbjct: 196 SCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGVMRN 250 >5ZFH-A nrPDB Length = 224 Score = 96.7 bits (239), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 62/226 (27%), Positives = 106/226 (46%), Gaps = 23/226 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G K + P+ ++ + CGG L+ +V+TAA C Q V LG+ + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQ----YQVQLGSDKI 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 ++ +++ + S GY + ++ND+ML++LD ++S V + LP G Sbjct: 57 G--DQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLP--EHCEPPG 112 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFV---NVTVTPEDQCRP--------NNVCTGVLTRRGG 195 T C V+GWG+ S FP + +V + +C+ +C G+ + Sbjct: 113 TSCTVSGWGTTTSPD--VTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTN 170 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWI 239 CNGD G PLVC G+ S+ PCG+ P +T+V ++ W+ Sbjct: 171 TCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWV 216 >1SPJ-A nrPDB Length = 238 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 69/242 (28%), Positives = 110/242 (45%), Gaps = 33/242 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ A++ + CGG L+H ++V+TAA C + LG ++L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDN----YQLWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREAN-LTSSVTIL 134 E ++ S G++ + +DLMLL+L A+ +T +V ++ Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 135 PLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCRPNNV------ 185 LP + E G+ C +GWGS FP + V++ + P D+C+ +V Sbjct: 117 ELPTEEP--EVGSTCLASGWGSIEPENF--SFPDDLQCVDLKILPNDECKKAHVQKVTDF 172 Query: 186 --CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDG 241 C G L C GD G PL+C+G+ GV S+ PCG P RV + WI+ Sbjct: 173 MLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIED 232 Query: 242 VL 243 + Sbjct: 233 TI 234 >4GSO-A nrPDB Length = 232 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 69/228 (30%), Positives = 107/228 (46%), Gaps = 25/228 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASC----FQSQNPGVSTVVLG 82 ++GG + + PFLA + + G +FCG LI+ +V+TAA C FQ Q GV + + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHCDSTNFQMQ-LGVHSKKVL 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 D + R + + +MSE D+ML++LD+ +++S I PL L + Sbjct: 59 NEDEQTRNPKEKFICPNKNMSE------VLDKDIMLIKLDKP--ISNSKHIAPLSLPSNP 110 Query: 143 VEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRR 193 G+ C++ GWGS P N+ + + C+ +C GVL Sbjct: 111 PSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGG 170 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFRDWI 239 C GD G PL+C G G+ S+ CG+GP +T V + DWI Sbjct: 171 KDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWI 218 >1SGF-A nrPDB Length = 240 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 111/233 (47%), Gaps = 33/233 (14%) Query: 39 PFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQ--- 95 P+ ++ ++ CGG L+ +V+TAA C+ + V LG + E + Sbjct: 16 PWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDK----YQVWLGKNNFLEDEPSDQHRLV 71 Query: 96 -------TFSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILPLPLQNATVEAGT 147 F++S ++E+ P+ + NDLMLL+L + A++T V + LP + + G+ Sbjct: 72 SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL--GS 129 Query: 148 RCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCRPNN--------VCTGVLTRRGGI 196 C +GWGS + ++P + VN+ + P + C + +C G + Sbjct: 130 TCLASGWGS--TTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYT 187 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWI-DGVLNNP 246 C D G PL+C+G+ G+ S+ PCG P +T++ F WI + + NNP Sbjct: 188 CEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP 240 >2EEK-A nrPDB Length = 220 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 16/222 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + S+ N G HFCGG+L+ +V++AA C++S V V LG + + Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKS----VLRVRLGEHHI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E + S S + Y ND+ML++L + A L V + LP + A Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAA--DA 113 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---RPNNV-----CTGVLTRRGGICN 198 T C V+GWG+ S + +++ + C P + C G L C Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWI 239 GD G P+VC G+ GV S+ G R P + +V + W+ Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWV 215 >6QHB-A nrPDB Length = 223 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 69/231 (29%), Positives = 102/231 (44%), Gaps = 23/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 +V G P+ A++ G CGG LIH +V+TAA C + P + V LG ++L Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC---KKPNLQ-VFLGKHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 ++E Q+ + ++ YD + D+MLL+L R A L S I PLPL+ Sbjct: 57 GQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKL--SELIQPLPLERDCSAQT 114 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQCRP--------NNVCTGVLTRRGG 195 T C + GWG G FP + + + ++C N +C G Sbjct: 115 TSCHILGWGKTADG----DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKD 170 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLN 244 C GD G PLVC G+ S+ PCG P +T V + +WI + Sbjct: 171 SCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1AO5-A nrPDB Length = 237 Score = 93.6 bits (231), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 110/243 (45%), Gaps = 31/243 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 +VGG P+ ++ Q H CGG L+ +V+TAA C+ Q V LG L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 56 Query: 87 RRRERQSRQTFSISSMSENGYD----------PQQNL-NDLMLLQLDREANLTSSVTILP 135 + E ++ S G++ P + +DLMLL+L + A++T V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRF--VNVTVTPEDQC------RPNNV-- 185 LP + + G++C +GWGS + R + V +T+ P + C + +V Sbjct: 117 LPTKEP--KPGSKCLASGWGS-ITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 173 Query: 186 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWI-DGV 242 C G + C D G PL+C+G+ G S+ PCG+ P +T + F WI D + Sbjct: 174 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 233 Query: 243 LNN 245 + N Sbjct: 234 MKN 236 >4DUR-A nrPDB Length = 791 Score = 93.6 bits (231), Expect = 7e-20, Method: Composition-based stats. Identities = 76/236 (32%), Positives = 112/236 (47%), Gaps = 24/236 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQ-SQNPGVSTVVLGAY 84 +VGG A P +P+ S++ + G HFCGG LI +V+TAA C + S P V+LGA+ Sbjct: 562 VVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAH 621 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 E ++ +S +P + D+ LL+L A +T V LP N V Sbjct: 622 QEVNLEPHVQEI----EVSRLFLEPTR--KDIALLKLSSPAVITDKVIPACLPSPNYVVA 675 Query: 145 AGTRCQVAGWG-SQRSGG----RLSRFPRFVNVTVTPED----QCRPNNVCTGVLTRRGG 195 T C + GWG +Q + G + ++ P N + + + +C G L Sbjct: 676 DRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTD 735 Query: 196 ICNGDGGTPLVC----EGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 C GD G PLVC + + GV S+ LG C R P + RV+ F WI+GV+ N Sbjct: 736 SCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGVMRN 790 >2PSX-A nrPDB Length = 227 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 65/207 (31%), Positives = 99/207 (47%), Gaps = 23/207 (11%) Query: 51 FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFS-ISSMSENGYDP 109 +CG L+H ++++TAA C + V V LG Y L +Q F + S+ GY Sbjct: 26 YCGAVLVHPQWLLTAAHCRKK----VFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH 81 Query: 110 QQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRF 169 + NDLML++L+R T V P+ + + AGT+C V+GWG+ +S FP+ Sbjct: 82 PGHSNDLMLIKLNRRIRPTKDVR--PINVSSHCPSAGTKCLVSGWGTTKSPQ--VHFPKV 137 Query: 170 V---NVTVTPEDQCR---PNNV-----CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFS 218 + N++V + +C P + C G R C GD G P+VC G G+ S+ Sbjct: 138 LQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS-CQGDSGGPVVCNGSLQGLVSWG 196 Query: 219 LGPCGRG--PDFFTRVALFRDWIDGVL 243 PC R P +T + F WI + Sbjct: 197 DYPCARPNRPGVYTNLCKFTKWIQETI 223 >2ASU-B nrPDB Length = 234 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 20/231 (8%) Query: 27 IVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 +VGG P P+ S++N QG+HFCGG+L+ ++++TA CF S + ++ + Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L + + + +++ P + L+LL+L+R L V ++ LP + V Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGS--QLVLLKLERSVTLNQRVALICLPPEWYVVPP 115 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 197 GT+C++AGWG + G + + V +C R + +CT L G C Sbjct: 116 GTKCEIAGWGETKGTGNDTVL-NVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGAC 174 Query: 198 NGDGGTPLVCEGLAHGVASFSLGP---CGRG--PDFFTRVALFRDWIDGVL 243 GD G PL C V + P C R P FTRV++F DWI V+ Sbjct: 175 EGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 225 >2AIQ-A nrPDB Length = 231 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 108/233 (46%), Gaps = 28/233 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + + FLA + G CGG LI+ +V+TA C + G + LG ++L Sbjct: 1 VIGGDECNINEHRFLALVYANGS-LCGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 87 RRRERQS------RQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + + + + F +++ ++ +D D+ML++L+R + +S I PL L + Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWD-----KDIMLIRLNRP--VRNSAHIAPLSLPS 108 Query: 141 ATVEAGTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCRP-------NNVCTGVLTR 192 G+ C++ GWG+ S L P N+ + C+ +C G+L Sbjct: 109 NPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEG 168 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+ S PC R P +T+V + DWI ++ Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >3T2N-A nrPDB Length = 372 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 70/244 (28%), Positives = 108/244 (44%), Gaps = 29/244 (11%) Query: 23 PLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 P+ IVGGR ++P+ S++ G H CGG+L+ +V+TAA CF +N +S + Sbjct: 114 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 173 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDP------QQNLNDLMLLQLDREANLTSSVTILPL 136 A + + Q + + GY P ++N ND+ L+ L LT + + L Sbjct: 174 AGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 233 Query: 137 PLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVC 186 P + G C V GWG+ + G+ + + V + D C +P C Sbjct: 234 PAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFC 293 Query: 187 TGVLTRRGGI--CNGDGGTPLVCEGLAH--------GVASFSLG-PCGRGPDFFTRVALF 235 G GGI C GD G P VCE G+ S+ G + P +T+V+ F Sbjct: 294 AGY--PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDF 351 Query: 236 RDWI 239 R+WI Sbjct: 352 REWI 355 >4MPW-A nrPDB Length = 245 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 79/245 (32%), Positives = 112/245 (45%), Gaps = 40/245 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG++A ++P+ S++ G HFCGG+LIH ++V+TAA C G L A Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-----GPDVKDLAA 55 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQ----QNLNDLMLLQLDREANLTSSVTILPLPLQ 139 ++ RE+ + +S PQ Q D+ LL+L+ ++S V + LP Sbjct: 56 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPA 115 Query: 140 NATVEAGTRCQVAGWGSQRSGGRL-SRFP-RFVNVTVTPEDQC----------------- 180 + T G C V GWG + RL FP + V V + C Sbjct: 116 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 175 Query: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVAL 234 R + +C G TRR C GD G PLVC+ L GV S+ G C + P +TRV Sbjct: 176 RDDMLCAGN-TRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTY 232 Query: 235 FRDWI 239 + DWI Sbjct: 233 YLDWI 237 >1P57-B nrPDB Length = 255 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 69/240 (28%), Positives = 106/240 (44%), Gaps = 29/240 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGR ++P+ S++ G H CGG+L+ +V+TAA CF +N +S + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 87 RRRERQSRQTFSISSMSENGYDP------QQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + Q + + GY P ++N ND+ L+ L LT + + LP Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + G C V GWG+ + G+ + + V + D C +P C G Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY- 179 Query: 191 TRRGGI--CNGDGGTPLVCEGLAH--------GVASFSLG-PCGRGPDFFTRVALFRDWI 239 GGI C GD G P VCE G+ S+ G + P +T+V+ FR+WI Sbjct: 180 -PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 238 >1YM0-A nrPDB Length = 238 Score = 92.4 bits (228), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 116/243 (47%), Gaps = 29/243 (11%) Query: 27 IVGGRKARPRQFPFLASI--QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 IVGG +ARP +FP+ S+ ++ HFCGG++I+ R+V+ AA C Q + P + ++V+G + Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 85 DLRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN-AT 142 D RQT + S+ N YDP ND+ +++ +T + + P+ + A Sbjct: 61 D-SSAASTVRQTHDVDSIFVNENYDPATLENDVSVIK--TAVAITFDINVGPICAPDPAN 117 Query: 143 VEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTVT---------PEDQCRPNNVC----TG 188 + Q +GWG+ SGG R+V + +T D + +C TG Sbjct: 118 DYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTG 177 Query: 189 VLTRRGGICNGDGGTPLVCEGLAH-----GVASFSLGPCGRGPDFFTRVALFRDWI-DGV 242 + R C GD G PL + + G+ S+ +G P ++RV WI D + Sbjct: 178 MTDRDS--CQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTI 235 Query: 243 LNN 245 NN Sbjct: 236 TNN 238 >1SI5-H nrPDB Length = 240 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/223 (28%), Positives = 107/223 (47%), Gaps = 28/223 (12%) Query: 40 FLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLR-RRERQSRQTFS 98 ++ S++ + +H CGG+LI +V+TA CF S++ LG +D+ R + + +Q + Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 99 ISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQR 158 +S + Y P+ +DL+L++L R A L V+ + LP +T+ T C V GWG Sbjct: 73 VSQLV---YGPEG--SDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYT- 126 Query: 159 SGGRLSR--FPRFVNVTVTPEDQCRPNN----------VCTGVLTRRGGICNGDGGTPLV 206 G ++ R ++ + ++C ++ +C G G C GD G PLV Sbjct: 127 --GLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLV 184 Query: 207 CEGLAHGVASFSLGPCGRG------PDFFTRVALFRDWIDGVL 243 CE + + P GRG P F RVA + WI ++ Sbjct: 185 CEQHKMRMVLGVIVP-GRGCAIPNRPGIFVRVAYYAKWIHKII 226 >3DFJ-A nrPDB Length = 263 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 102/237 (43%), Gaps = 24/237 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAYD 85 I GG A Q+P+ SI +G H CGG+L+ ++V++AA CF S+ + V LGA+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L ++ + + Y + + D+ LLQL R + + + LP NA+ Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 146 GTRCQVAGWGS--------------QRSGGRLSRFP--RFVNVTVTPEDQ--CRPNNVCT 187 G C V GWG Q +SR N+ PE+ + + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 188 GVLTRRGGICNGDGGTPLVC--EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDWI 239 G + C GD G PL C EGL + S G CG P +T + + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 >1LTO-A nrPDB Length = 245 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 110/245 (44%), Gaps = 40/245 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQGR---HFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG++A ++P+ S++ + R HFCGG+LIH ++V+TAA C G L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCL-----GPDVKDLAT 55 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQ----QNLNDLMLLQLDREANLTSSVTILPLPLQ 139 ++ RE+ + +S PQ Q D+ LL+L+ N++S V + LP Sbjct: 56 LRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPA 115 Query: 140 NATVEAGTRCQVAGWGSQRSGGRL-SRFP-RFVNVTVTPEDQC----------------- 180 + T G C V GWG + L FP + V V + C Sbjct: 116 SETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRII 175 Query: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVAL 234 R + +C G R C GD G PLVC+ L GV S+ G C + P +TRV Sbjct: 176 RDDMLCAGNSQRDS--CKGDSGGPLVCKVNGTWLQAGVVSWDEG-CAQPNRPGIYTRVTY 232 Query: 235 FRDWI 239 + DWI Sbjct: 233 YLDWI 237 >3F6U-H nrPDB Length = 240 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 104/242 (42%), Gaps = 25/242 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHF-CGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 ++ G+ R P+ + + + CG LIH +V+TAA C + V LG YD Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLL--VRLGEYD 58 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLP----LQNA 141 LRR E+ Y ND+ LL L + A L+ ++ + LP + Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPR-----FVNVTVTPEDQCRP--------NNVCTG 188 +AG V GWG S + ++ R F+ + V P ++C N +C G Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAG 178 Query: 189 VLTRRGGICNGDGGTPLVC--EGLAHGVASFSLGP-CGRGPDF--FTRVALFRDWIDGVL 243 +L R C GD G P+V G V S G CG ++ +T+V+ + DWI G + Sbjct: 179 ILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHI 238 Query: 244 NN 245 + Sbjct: 239 RD 240 >4XDE-A nrPDB Length = 257 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 107/240 (44%), Gaps = 30/240 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAYD 85 +VGG A P++A++ G FC G+LI +V+TAA C Q + P TVVLG + Sbjct: 3 VVGGLVALRGAHPYIAAL-YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQ-E 60 Query: 86 LRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREAN-----LTSSVTILPLPLQ 139 R + QT ++ S + P +DL LL+L +A+ L+ V + LP Sbjct: 61 RRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSG 120 Query: 140 NATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCR----------PNNVCTG 188 A T CQVAGWG Q G + F + V ++C P +C G Sbjct: 121 AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAG 180 Query: 189 VLTRRGGICNGDGGTPLVCEGLA-------HGVASFSLGPCG--RGPDFFTRVALFRDWI 239 L C GD G PLVCE A G+ S+ G CG P +T VA + WI Sbjct: 181 FLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSG-CGDRNKPGVYTDVAYYLAWI 239 >3E0N-B nrPDB Length = 271 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 103/246 (41%), Gaps = 24/246 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAYD 85 I GG A Q+P+ SI +G H CGG+L+ ++V++AA CF S+ + V LGA+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L ++ + + Y + + D+ LLQL R + + + LP A+ Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 146 GTRCQVAGWG--------------SQRSGGRLSRFP--RFVNVTVTPEDQ--CRPNNVCT 187 G C V GWG Q +SR N+ PE+ + + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 188 GVLTRRGGICNGDGGTPLVC--EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDWIDGV 242 G + C GD G PL C EGL + S G CG P +T + + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSK 240 Query: 243 LNNPGP 248 + P Sbjct: 241 VTELQP 246 >5TJX-A nrPDB Length = 263 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 66/233 (28%), Positives = 104/233 (44%), Gaps = 22/233 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQS---QNPGVSTVV 80 IVGG ++ ++P+ S+Q + RH CGG+LI ++V+TAA CF Q+ V + Sbjct: 16 IVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD--VWRIY 73 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 G +L + + + + Y + +D+ L++L T + LP + Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKG 133 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLT 191 T T C V GWG + G + + VN+ + ++C+ VC G Sbjct: 134 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 193 Query: 192 RRGGICNGDGGTPLVCE--GLAHGVASFSLGP-CGR--GPDFFTRVALFRDWI 239 C GD G PLVC+ G+ V S G C R P +T+VA + DWI Sbjct: 194 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 246 >4DGJ-A nrPDB Length = 235 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 110/240 (45%), Gaps = 27/240 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN--PGVSTVVLGAY 84 IVGG A+ +P++ + R CG +L+ + ++++AA C +N P T +LG + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 85 DLRRRERQSRQTFS--ISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 + S QT I + N Y+ ++ ND+ ++ L+ + N T + + LP +N Sbjct: 61 --MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQ 118 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTR 192 G C +AGWG+ G + + +V + ++C+ N +C G Sbjct: 119 VFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY--E 176 Query: 193 RGGI--CNGDGGTPLVCE----GLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLN 244 GGI C GD G PL+C+ GV SF C P + RV+ F +WI L+ Sbjct: 177 EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGY-ECALPNRPGVYARVSRFTEWIQSFLH 235 >5GVT-A nrPDB Length = 250 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/234 (27%), Positives = 102/234 (43%), Gaps = 24/234 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLG 82 IVGG A ++P+ S+Q + H CGG++I ++V+TAA CF P V + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 L +++ + + Y + D+ L++L N T + LP + T Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRR 193 T C V GWG + G + + + P ++C+ +C G + Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGY--KE 178 Query: 194 GGI--CNGDGGTPLVCEGLAH----GVASFSLGPCGRG--PDFFTRVALFRDWI 239 GG C GD G PLVC+ G+ S+ G C R P +T+V+ + DWI Sbjct: 179 GGTDACKGDSGGPLVCKHSGRWQLVGITSWGEG-CARKDQPGVYTKVSEYMDWI 231 >1OP0-A nrPDB Length = 234 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 104/229 (45%), Gaps = 25/229 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASC----FQSQNPGVSTVVLG 82 ++GG + + FL + N FCGG LI+ +V+TAA C FQ Q S VL Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 + R ++ F + + N + D+ML++LD+ +++S I PL L ++ Sbjct: 61 E---DEQTRNPKEKFICPNKNNNEVLDK----DIMLIKLDKP--ISNSKHIAPLSLPSSP 111 Query: 143 VEAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTR 192 G+ C++ GWGS P N+ + C+ +C G++ Sbjct: 112 PSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQG 171 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFRDWI 239 C GD G PL+C G G+ S+ PCG+GP +T V + DWI Sbjct: 172 GKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWI 220 >2CGA-A nrPDB Length = 245 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 112/243 (46%), Gaps = 32/243 (13%) Query: 22 SPLLDIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVST-- 78 S L IV G +A P +P+ S+Q++ G HFCGG+LI+ +V+TAA C GV+T Sbjct: 11 SGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC------GVTTSD 64 Query: 79 -VVLGAYDLRRRERQSRQTFSISSMSENG-YDPQQNLNDLMLLQLDREANLTSSVTILPL 136 VV G +D + + Q I+ + +N Y+ ND+ LL+L A+ + +V+ + L Sbjct: 65 VVVAGEFD-QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCL 123 Query: 137 PLQNATVEAGTRCQVAGWGSQR-----SGGRLSR--FPRFVNVTVTPE--DQCRPNNVCT 187 P + AGT C GWG R + RL + P N + + +C Sbjct: 124 PSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICA 183 Query: 188 GVLTRRGGI--CNGDGGTPLVCE----GLAHGVASFSLGPCGRG-PDFFTRVALFRDWID 240 G G+ C GD G PLVC+ G+ S+ C P + RV +W+ Sbjct: 184 GA----SGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQ 239 Query: 241 GVL 243 L Sbjct: 240 QTL 242 >4LK4-A nrPDB Length = 357 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 110/239 (46%), Gaps = 34/239 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQGR-----HFCGGALIHARFVMTAASCFQSQNPGVSTVVL 81 I+ G A ++P + ++ +G FCGG+ + R+V+TAA CF S++ V++ Sbjct: 11 IINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDVII 70 Query: 82 GAYDLRRR---ERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL 138 GAYDL ER + Q Y P LND+ +++L + ++L + L P Sbjct: 71 GAYDLNNSSQGERIAAQKI----YRHLSYSPSNLLNDIAIVELAQTSSLPA--ITLAGPA 124 Query: 139 QNATVEAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTVTPEDQCR----------PN--N 184 ++ A T VAGWG Q + + + V+V + + C+ PN N Sbjct: 125 TRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTN 184 Query: 185 VCTGVLTRRGGICNGDGGTPLVCEGLAH--GVASFSLGPCGRGPDF--FTRVALFRDWI 239 C LT+ C GD G P+V + G+ S+ C + + +T V+ FRDWI Sbjct: 185 FCAARLTKDS--CQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWI 241 >1A5I-A nrPDB Length = 265 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 111/257 (43%), Gaps = 37/257 (14%) Query: 18 RAGSSPLLDIVGGRKARPRQFPFLASIQNQGRH------FCGGALIHARFVMTAASCFQ- 70 R P L GG P+ A+I Q R CGG LI + +V+TAA CFQ Sbjct: 5 RKYKEPQLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQE 64 Query: 71 SQNPGVSTVVLGAYDLRRRERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLDRE----A 125 S P VVLG R + + QTF + + +D ND+ LLQL + A Sbjct: 65 SYLPDQLKVVLGR-TYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCA 123 Query: 126 NLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQCRP-- 182 + SV + LP N + T C+++G+G +S S + +V + P +C P Sbjct: 124 QESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKF 183 Query: 183 -------NNVCTGVLTRRGGI-------CNGDGGTPLVCEGLAH----GVASFSLGPCGR 224 NN+ TR G I C GD G PLVC H G+ S+ +G CG Sbjct: 184 LFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVG-CGE 242 Query: 225 G--PDFFTRVALFRDWI 239 P +T+V + WI Sbjct: 243 KDVPGVYTKVTNYLGWI 259 >1X7A-C nrPDB Length = 235 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/232 (29%), Positives = 107/232 (46%), Gaps = 23/232 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGAYD 85 IVGG A+P QFP+ + + FCGG++I+ ++V+TAA C + PGV TVV G Y+ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIE---PGVKITVVAGEYN 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNL--NDLMLLQLDREANLTSSVT---ILPLPLQN 140 E ++ I ++ + Y+ N +D+ LL+LD L S VT I N Sbjct: 58 TEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTN 117 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTR 192 ++ G+ V+GWG + GR + +++ V + C N C G Sbjct: 118 IFLKFGSG-YVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEG 176 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRGP-DFFTRVALFRDWI 239 C GD G P V E G+ S+ +G +T+V+ + +WI Sbjct: 177 GKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWI 228 >3P8G-A nrPDB Length = 241 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 109/240 (45%), Gaps = 32/240 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGR-HFCGGALIHARFVMTAASC------FQSQNPGVSTV 79 +VGG A ++P+ S+ G+ H CG +LI ++++AA C F+ +P T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 80 VLGAYDLRRR------ERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTI 133 LG +D +R ER+ ++ S ++ +D D+ LL+L++ A +S V Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFD-----YDIALLELEKPAEYSSMVRP 115 Query: 134 LPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNV 185 + LP + AG V GWG + GG + + + V + C P + Sbjct: 116 ICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMM 175 Query: 186 CTGVLTRRGGICNGDGGTPLV---CEG--LAHGVASFSLGPCGRG-PDFFTRVALFRDWI 239 C G L+ C GD G PL +G GV S+ G R P +TR+ LFRDWI Sbjct: 176 CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 235 >1EKB-B nrPDB Length = 235 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/238 (26%), Positives = 107/238 (44%), Gaps = 23/238 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN--PGVSTVVLGAY 84 IVGG +R +P++ ++ + CG +L+ ++++AA C +N P VLG + Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 85 DLRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +T I + N Y+ ++ ND+ ++ L+ + N T + + LP +N Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRRG 194 G C +AGWG+ G + + +V + ++C+ N VC G G Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGY--EAG 178 Query: 195 GI--CNGDGGTPLVCE----GLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLN 244 G+ C GD G PL+C+ L GV SF C P + RV F +WI L+ Sbjct: 179 GVDSCQGDSGGPLMCQENNRWLLAGVTSFGY-QCALPNRPGVYARVPRFTEWIQSFLH 235 >1FON-A nrPDB Length = 240 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 76/242 (31%), Positives = 102/242 (42%), Gaps = 34/242 (14%) Query: 30 GRKARPRQFPFLASIQNQG----RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 G A P + + S+Q + H CGG+LI +V+TA C + VVLG YD Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSR--TYQVVLGEYD 59 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLN------DLMLLQLDREANLTSSVTILPLPLQ 139 R S Q I++ + P N N D+ L++L R A L V + LP Sbjct: 60 -RSVLEGSEQVIPINA-GDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPA 117 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGV 189 + C ++GWG +GG L + + + C + VC G Sbjct: 118 GDILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG 177 Query: 190 LTRRGGICNGDGGTPLVCEGL-----AHGVASF-SLGPCG--RGPDFFTRVALFRDWIDG 241 TR G CNGD G PL C HGV SF S C + P FTRV+ F DWID Sbjct: 178 DTRSG--CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDE 235 Query: 242 VL 243 + Sbjct: 236 TI 237 >4E7N-A nrPDB Length = 238 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 33/239 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH--FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 I+GG + + FL ++ FCGG LI+ +V+TAA C + + LG + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKN----FRIKLGMH 56 Query: 85 DLR--RRERQSR----QTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL 138 + + Q+R + F +SS + +D D+ML++LD + + +S I P L Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWD-----KDIMLIRLD--SPVKNSKHIAPFSL 109 Query: 139 QNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCRP-----------NNVC 186 ++ G+ C++ GWG + G P VN+ + + CR +C Sbjct: 110 PSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLC 169 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 G+L C GD G PL+C G G+AS+ PC + P +T+V DWI+ ++ Sbjct: 170 AGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >2PKA-B nrPDB Length = 152 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 52/147 (35%), Positives = 73/147 (49%), Gaps = 16/147 (10%) Query: 114 NDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFV 170 +DLMLL+L A +T +V +L LP Q E G+ C+ +GWGS G FP + V Sbjct: 8 HDLMLLRLQSPAKITDAVKVLELPTQEP--ELGSTCEASGWGSIEPGPDDFEFPDEIQCV 65 Query: 171 NVTVTPEDQC---RPNNV-----CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPC 222 +T+ C P+ V C G L C GD G PL+C G+ G+ S+ PC Sbjct: 66 QLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPC 125 Query: 223 GRG--PDFFTRVALFRDWIDGVL-NNP 246 G P +T++ + DWID + NP Sbjct: 126 GSANKPSIYTKLIFYLDWIDDTITENP 152 >6I44-A nrPDB Length = 627 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 65/231 (28%), Positives = 99/231 (42%), Gaps = 18/231 (7%) Query: 27 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVLG 82 IVGG ++ ++P+ S+Q RH CGG+LI ++V+TAA CF V + G Sbjct: 380 IVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 439 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 L + + + + Y + +D+ L++L T + LP + T Sbjct: 440 ILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSKGDT 499 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRR 193 T C V GWG G + + VN+ + ++C+ VC G Sbjct: 500 STIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 559 Query: 194 GGICNGDGGTPLVCE--GLAHGVASFSLGP-CGR--GPDFFTRVALFRDWI 239 C GD G PLVC+ G+ V S G C R P +T+VA + DWI Sbjct: 560 KDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 610 >2F91-A nrPDB Length = 237 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 98/237 (41%), Gaps = 29/237 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQ----GRHFCGGALIHARFVMTAASCF---QSQNPGVSTV 79 IVGG A +FP+ S Q HFCG ++ + + +TA C +NP + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 80 VLGAYDLRRRERQSRQTFSISS--MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLP 137 V G D+ E S Q ++S + EN +D ND+ LL+L +V + LP Sbjct: 61 VAGELDMSVNEG-SEQIITVSKIILHEN-FDYNLLDNDISLLKLSGSLTFNDNVAPIALP 118 Query: 138 LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTG 188 Q T A V GWG+ GG + V V + ++ CR + +C G Sbjct: 119 EQGHT--ATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAG 176 Query: 189 VLTRRGGICNGDGGTPLVCEGLAH----GVASFSLGPCGR--GPDFFTRVALFRDWI 239 V C GD G PL G+ S+ G C R P +T V+ DWI Sbjct: 177 VPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYG-CARPGYPGVYTEVSYHVDWI 232 >4H4F-A nrPDB Length = 249 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 109/240 (45%), Gaps = 32/240 (13%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG ARP +P+ S+Q + RH CGG LI + FV+TAA C N V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--SNTRTYRVAVG 58 Query: 83 AYDLRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 +L + + + ++ ++ ND+ L++L L+ ++ + LP +++ Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRF------PRFVNVTVTPED----QCRPNNVCT---G 188 + C V GWG + G ++ P + T + D + + VC G Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 178 Query: 189 VLTRRGGICNGDGGTPLVCE-----GLAHGVASF-SLGPCG--RGPDFFTRVALFRDWID 240 V++ CNGD G PL C+ G+ SF S C + P +TRV+ + DWI+ Sbjct: 179 VIS----ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 234 >5XRF-A nrPDB Length = 242 Score = 81.3 bits (199), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/237 (28%), Positives = 114/237 (48%), Gaps = 31/237 (13%) Query: 27 IVGGRKARPRQFPFLASI--QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 ++GG + + FLA+ C G LIH +V+ AA C++ G++ + LG + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKR---GLN-IYLGMH 62 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNL----NDLMLLQLDREANLTSSVTILPLPLQN 140 + + ++ ++I E+ Y + L D++LL+L++ +++S I PL L + Sbjct: 63 NQSIQFDDEQRRYAIE---EHYYRCDEKLTKWEKDVVLLKLNKP--VSNSTHIAPLSLPS 117 Query: 141 ATVEAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRPNN---------VCTGVL 190 + G+ C+V GWG S L P N+ + +C + +C GVL Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVL 177 Query: 191 TRRGGI--CNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 GGI CN D G PL+C+G G+ F PC + P +TRV+ + DWI ++ Sbjct: 178 --EGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >3S69-A nrPDB Length = 234 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 103/233 (44%), Gaps = 25/233 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASC----FQSQNPGVSTVVLG 82 ++GG + + L + N FC G LI+ +V+TAA C FQ + S VL Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 + R ++ F + N + + D+ML++LD + +++S I+PL L ++ Sbjct: 61 E---DEQTRNPKEKF----ICPNKKNDEVLDKDIMLIKLD--SRVSNSEHIVPLSLPSSP 111 Query: 143 VEAGTRCQVAGWGSQR----------SGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTR 192 G+ C + GWGS ++ V PE +C G+L Sbjct: 112 PSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEG 171 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+ SF PCG+G P +T+V + WI ++ Sbjct: 172 GKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >2V35-A nrPDB Length = 240 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 109/241 (45%), Gaps = 28/241 (11%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG +A+ +P S+Q + H CGG LI +VMTAA C + VV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDREL--TFRVVVG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNL---NDLMLLQLDREANLTSSVTILPLPLQ 139 ++L + + + Q + + + Y ++ D+ LL+L + L S V + LP Sbjct: 59 EHNLNQND-GTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRA 117 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN----------VCTGV 189 + + C + GWG R+ G+L++ + + C ++ VC G Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG 177 Query: 190 LTRRGGICNGDGGTPLVC----EGLAHGVASF--SLG-PCGRGPDFFTRVALFRDWIDGV 242 R G C GD G PL C + HGV SF LG R P FTRV+ + WI+ V Sbjct: 178 DGVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNV 236 Query: 243 L 243 + Sbjct: 237 I 237 >5LPF-A nrPDB Length = 234 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/224 (29%), Positives = 104/224 (46%), Gaps = 23/224 (10%) Query: 39 PFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFS 98 P+ S+ N C G L+ +V+TAA C P + V L + E+ R T S Sbjct: 16 PWQVSLFNGLSFHCAGVLVDQSWVLTAAHC--GNKPLWARVGDDHLLLLQGEQLRRTTRS 73 Query: 99 I-SSMSENGYDP----QQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAG 153 + G P + + +DLMLL+L R L V L LP + A + G +CQVAG Sbjct: 74 VVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA--QPGDQCQVAG 131 Query: 154 WGSQRSGGRLSRFPRFV---NVTVTPEDQCR-------PNNVCTGVLTRRGGICNGDGGT 203 WG+ + R ++ + + ++T+ +C NN+ L R C D G Sbjct: 132 WGT--TAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGG 189 Query: 204 PLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLNN 245 PLVC+ G+ S+ + PCG + P +T++ + WI+ V+ + Sbjct: 190 PLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 233 >3LC3-A nrPDB Length = 235 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 106/232 (45%), Gaps = 23/232 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGAYD 85 +VGG A+P QFP+ + + FCGG++++ ++++TAA C ++ GV TVV G ++ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVET---GVKITVVAGEHN 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNL--NDLMLLQLDREANLTSSVT---ILPLPLQN 140 + E ++ I + + Y+ N +D+ LL+LD L S VT I N Sbjct: 58 IEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTN 117 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTR 192 ++ G+ V+GWG GR + +++ V + C N C G Sbjct: 118 IFLKFGSG-YVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEG 176 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRGP-DFFTRVALFRDWI 239 C GD G P V E G+ S+ +G +T+V+ + +WI Sbjct: 177 GRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWI 228 >2OQ5-A nrPDB Length = 232 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/231 (27%), Positives = 100/231 (43%), Gaps = 23/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG + ++P+ AS+Q G H CG LI+A ++++AA CF + +NP T G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG--- 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + + ++ + E P + D+ L +L T++V + LP + + Sbjct: 58 VTIKPSKMKRGLRRIIVHEKYKHPSHDY-DISLAELSSPVPYTNAVHRVCLPDASYEFQP 116 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----------PNNVCTGVLTRRGG 195 G V G+G+ ++ G R VT+ C P +C G L + Sbjct: 117 GDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTD 176 Query: 196 ICNGDGGTPLVCEG-----LAHGVASFSLGPCGR--GPDFFTRVALFRDWI 239 C GD G PLV G+ S+ C + P +TRV RDWI Sbjct: 177 ACQGDSGGPLVSSDARDIWYLAGIVSWG-DECAKPNKPGVYTRVTALRDWI 226 >2B9L-A nrPDB Length = 394 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 111/254 (43%), Gaps = 41/254 (16%) Query: 32 KARPRQFPFLASI--------QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVL-- 81 +A +FP++ ++ + + CGG+LI V+T A C S + + + Sbjct: 136 EAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRA 195 Query: 82 GAYD-LRRRERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQ 139 G +D L +ER Q I + + ++P+ +ND+ LL LDR ++ + LP Q Sbjct: 196 GEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQ 255 Query: 140 NATVEAGTRCQVAGWGSQRSGG--RLSRFPRFVNVTVTPEDQCRPN-------------- 183 + ++ T C +GWG + G R S + + + D+C+ + Sbjct: 256 SQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQ 314 Query: 184 -NVCTGVLTRRGGICNGDGGTPLVCEG-------LAHGVASFSLGPCGRG--PDFFTRVA 233 VC G + C GDGG+PL C + G+ ++ +G CG P + VA Sbjct: 315 TFVCAGGEQGK-DTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIG-CGDENVPGVYANVA 372 Query: 234 LFRDWIDGVLNNPG 247 FR+WID + G Sbjct: 373 HFRNWIDQEMQAKG 386 >1PYT-D nrPDB Length = 251 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 101/239 (42%), Gaps = 31/239 (12%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG A P +P+ S+Q N RH CGG LI V+TAA C N V LG Sbjct: 14 VVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI--SNTLTYRVALG 71 Query: 83 AYDLRRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 +L + + ++ ++ ND+ L++L L ++ + LP + + Sbjct: 72 KNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEGS 131 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRF------PRFVNVTVTPEDQ----CRPNNVCT---G 188 + C V GWG + G ++ P T + D + VC G Sbjct: 132 LLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCAGGDG 191 Query: 189 VLTRRGGICNGDGGTPLVCEGLAH----GVASFSLG-PCG--RGPDFFTRVALFRDWID 240 V++ CNGD G PL C+ G+ SF G C + P FTRV+ + DWI+ Sbjct: 192 VISA----CNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWIN 246 >1BDA-A nrPDB Length = 265 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 76/260 (29%), Positives = 111/260 (42%), Gaps = 43/260 (16%) Query: 18 RAGSSPLLDIVGGRKARPRQFPFLASIQNQGRH------FCGGALIHARFVMTAASCFQS 71 R S P I GG A P+ A+I + R CGG LI + ++++AA CFQ Sbjct: 5 RQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQE 64 Query: 72 QNPGVSTVVLGAYDLRRRERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLD----REAN 126 + P V+ R + Q F + + +D ND+ LLQL R A Sbjct: 65 RFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQ 124 Query: 127 LTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP----RFVNVTVTPEDQCRP 182 +S V + LP + + T C+++G+G + LS F + +V + P +C Sbjct: 125 ESSVVRTVCLPPADLQLPDWTECELSGYGKHEA---LSPFYSERLKEAHVRLYPSSRCTS 181 Query: 183 ----------NNVCTGVLTRRGG-------ICNGDGGTPLVCEGLAH----GVASFSLGP 221 N +C G TR GG C GD G PLVC G+ S+ LG Sbjct: 182 QHLLNRTVTDNMLCAGD-TRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLG- 239 Query: 222 CGRG--PDFFTRVALFRDWI 239 CG+ P +T+V + DWI Sbjct: 240 CGQKDVPGVYTKVTNYLDWI 259 >3VGC-B nrPDB Length = 131 Score = 77.4 bits (189), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 49/137 (35%), Positives = 75/137 (54%), Gaps = 12/137 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVST---VVLG 82 IV G +A P +P+ S+Q++ G HFCGG+LI+ +V+TAA C GV+T VV G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC------GVTTSDVVVAG 54 Query: 83 AYDLRRRERQSRQTFSISSMSENG-YDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 +D + + Q I+ + +N Y+ ND+ LL+L A+ + +V+ + LP + Sbjct: 55 EFD-QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASD 113 Query: 142 TVEAGTRCQVAGWGSQR 158 AGT C GWG R Sbjct: 114 DFAAGTTCVTTGWGLTR 130 >1BQY-A nrPDB Length = 234 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 62/233 (26%), Positives = 107/233 (45%), Gaps = 25/233 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNP----GVSTVVLG 82 + GG + + L + N CGG LI+ +V+TAA C S N GV + + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC-DSNNFQLLFGVHSKKIL 59 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 D + R+ + + F + ++ D D+ML++LD +++++S I PL L ++ Sbjct: 60 NEDEQTRDPKEK-FFCPNRKKDDEVD-----KDIMLIKLD--SSVSNSEHIAPLSLPSSP 111 Query: 143 VEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTVTPEDQCRP---------NNVCTGVLTR 192 G+ C++ GWG + P N+ + CR +C G+L Sbjct: 112 PSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQG 171 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C+ D G PL+C G+ G+ S+ PCG+ P +T+V + DWI ++ Sbjct: 172 GRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >1M9U-A nrPDB Length = 241 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 100/239 (41%), Gaps = 28/239 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 ++GG A P +FP+ S Q Q H CG +L+ + ++A+ C P V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 84 YDLRRRERQSRQTFSISS--MSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + ++ + QT ++ S M EN G ND+ +L L +L ++ LP N Sbjct: 61 W--QQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP------------NNVCTG 188 AGT C ++GWG L + ++ V QC N++C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 189 VLTRRGGICNGDGGTPLVCE-------GLAHGVASFSLGPC-GRGPDFFTRVALFRDWI 239 G CNGD G PL C G+ V S LG C P +TRV+ + WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 >6AOD-C nrPDB Length = 245 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 40/242 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLG 82 IVGG + ++P+ ++ RH CGG++I ++++TAA CF ++P + V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 83 AYDLRRRERQSRQTF---------SISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTI 133 L++ E + +F M+E+GY D+ LL+L+ T S Sbjct: 61 I--LQQSEIKEDTSFFGVQEIIIHDQYKMAESGY-------DIALLKLETTVQYTDSQRP 111 Query: 134 LPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NN 184 + LP + T C V GWG ++ ++ + + + ++C+ Sbjct: 112 ISLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKM 171 Query: 185 VCTGVLTRRGG--ICNGDGGTPLVCEG--LAH--GVASFSLGPCGRG-PDFFTRVALFRD 237 +C G R GG C GD G PL C+ + H G+ S+ G R P +T V + D Sbjct: 172 ICAGY--REGGKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 229 Query: 238 WI 239 WI Sbjct: 230 WI 231 >2OLG-A nrPDB Length = 278 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 66/254 (25%), Positives = 105/254 (41%), Gaps = 41/254 (16%) Query: 27 IVGGRKARPRQFPFLASI-----QNQGRHFCGGALIHARFVMTAASCFQSQ--------- 72 I+ G P +FP+ A I N + CGG+LI+ R+++TAA C + Sbjct: 23 ILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGALN 82 Query: 73 -------NPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQN-LNDLMLLQLDRE 124 N GA + ++ + + D ++ +D+ L++L+R+ Sbjct: 83 KVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLNRQ 142 Query: 125 ANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN 184 T+ + + LP N V+ G R V GWG +G + S + + V V +QC Sbjct: 143 VEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETG-QYSTIKQKLAVPVVHAEQCAKTF 201 Query: 185 VCTGVLTRRGGIC----------NGDGGTPLVCEG-----LAHGVASFSLGPCGR--GPD 227 GV R +C GD G PL+ E G+ SF CG P Sbjct: 202 GAAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFG-ATCGTEGWPG 260 Query: 228 FFTRVALFRDWIDG 241 +T+V +RDWI+G Sbjct: 261 IYTKVGKYRDWIEG 274 >1FXY-A nrPDB Length = 228 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/238 (25%), Positives = 106/238 (44%), Gaps = 35/238 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASC-FQSQNPGVSTVVLGAY 84 IVGG + + P+ A + N+ FCGG ++ +++TAA C +Q++ + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR----------F 50 Query: 85 DLRRRERQSRQTFSISSMSE-------NGYDPQQNLNDLMLLQLDREANLTSSVTILPLP 137 +R +R + Q ++ E N + + D+ +L+L + +T + + P Sbjct: 51 KVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRL--KTPITFRMNVAPAS 108 Query: 138 LQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQCRP--------NNVC 186 L A GT+C ++GWG+ S G + +P + ++ V + +C N C Sbjct: 109 LPTAPPATGTKCLISGWGNTASSG--ADYPDELQCLDAPVLSQAKCEASYPGKITSNMFC 166 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 G L C GD G P+VC G GV S+ G + P +T+V + WI + Sbjct: 167 VGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >2F83-A nrPDB Length = 625 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 65/242 (26%), Positives = 107/242 (44%), Gaps = 40/242 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLG 82 IVGG + ++P+ ++ RH CGG++I ++++TAA CF ++P + V G Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 447 Query: 83 AYDLRRRERQSRQTF---------SISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTI 133 L + E + +F M+E+GY D+ LL+L+ N T S Sbjct: 448 I--LNQSEIKEDTSFFGVQEIIIHDQYKMAESGY-------DIALLKLETTVNYTDSQRP 498 Query: 134 LPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NN 184 + LP + T C V GWG ++ ++ + + + ++C+ Sbjct: 499 ICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKM 558 Query: 185 VCTGVLTRRGG--ICNGDGGTPLVCEG--LAH--GVASFSLGPCGRG-PDFFTRVALFRD 237 +C G R GG C GD G PL C+ + H G+ S+ G R P +T V + D Sbjct: 559 ICAGY--REGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616 Query: 238 WI 239 WI Sbjct: 617 WI 618 >5XW8-A nrPDB Length = 133 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 43/132 (32%), Positives = 72/132 (54%), Gaps = 7/132 (5%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S+ V LG +++ Sbjct: 9 IVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGEHNI 63 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + ++ ++ ND+ML++L A L S V + LP A AG Sbjct: 64 DVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAA--AG 121 Query: 147 TRCQVAGWGSQR 158 T C ++GWG+ + Sbjct: 122 TECLISGWGNTK 133 >1FIZ-A nrPDB Length = 263 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 37/247 (14%) Query: 27 IVGGRKARPRQFPFLASIQ------NQGRHFCGGALIHARFVMTAASCFQSQNP------ 74 +VGG A P +P++ S+Q N+ H CGG L+++ +V+TAA CF+++ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 75 --GVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVT 132 G + VV G+ + Q R F + Y +ND+ L+++ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQER--FVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIG 118 Query: 133 ILPLP-LQNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQC---------- 180 LP + A C V GWG + G R S + V + + C Sbjct: 119 PGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRI 178 Query: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAH------GVASFSLGPCGRG--PDFFTRV 232 R NVC G + C GD G PL+C A G+ S+ +G C R P +T Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTST 237 Query: 233 ALFRDWI 239 + +WI Sbjct: 238 WPYLNWI 244 >6BQM-A nrPDB Length = 506 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 66/246 (26%), Positives = 108/246 (43%), Gaps = 41/246 (16%) Query: 27 IVGGRKARPRQFPFLASI--QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 I+GG +A ++P++ ++ +N FCGG+ + R+V+TAA C ++P V+LGA+ Sbjct: 11 IIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLGAF 70 Query: 85 DLRR---RER-QSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 D+ ER RQ + N Y ND+ +L+L+R+ SV I N Sbjct: 71 DMNDVNTAERIHVRQIY-----VHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDFN 125 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFP----RFVNVTVTPEDQCRP-------------- 182 + + V G+G+++ P V V P +C+ Sbjct: 126 ELTK-DSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQL 184 Query: 183 --NNVCTGVLTRRGGICNGDGGTPLVCEG----LAHGVASFSLGPCGRG--PDFFTRVAL 234 N C G + C+GD G P+ + GV S+ G CGR P +T +++ Sbjct: 185 TNNAFCAGSFGKDA--CSGDAGGPIFFDSNNGRKQMGVVSWGDG-CGRANSPGVYTNLSV 241 Query: 235 FRDWID 240 F DW+D Sbjct: 242 FNDWLD 247 >4FXG-H nrPDB Length = 242 Score = 73.2 bits (178), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 65/248 (26%), Positives = 111/248 (44%), Gaps = 36/248 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I GG+KA+P FP+ I G GAL++ +V+TAA Q S + + L Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILPLPLQNA---- 141 +R Q +S + GY ND+ L++L+ + + S++T + LP + A Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 142 -TVEAGTRCQVAGWG-SQRSGGRLSRFPRFVNVTVTPEDQC-----RP---------NNV 185 T + GT +GWG +QR G L+R +V++ + +C +P N + Sbjct: 119 RTDDIGT---ASGWGLTQR--GFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANML 173 Query: 186 CTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFSLGPCGRGPDF--FTRVALFRD 237 C G+ + C GD G LV G+ S+ CG + +T+V + Sbjct: 174 CAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 233 Query: 238 WIDGVLNN 245 WI+ ++++ Sbjct: 234 WIENIISD 241 >1ZJK-A nrPDB Length = 403 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 71/271 (26%), Positives = 119/271 (43%), Gaps = 41/271 (15%) Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVM 63 L V + GL A + G I GG+KA+P FP+ I G GAL++ +V+ Sbjct: 144 LPVCEPVCGLSARTTGGQ-----IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVL 196 Query: 64 TAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNL-NDLMLLQLD 122 TAA Q S + + L+R Q +S + GY ND+ L++L+ Sbjct: 197 TAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLN 256 Query: 123 REANLTSSVTILPLPLQNA-----TVEAGTRCQVAGWG-SQRSGGRLSRFPRFVNVTVTP 176 + + S++T + LP + A T + GT +GWG +QR G L+R +V++ + Sbjct: 257 NKVVINSNITPICLPRKEAESFMRTDDIGT---ASGWGLTQR--GFLARNLMYVDIPIVD 311 Query: 177 EDQC-----RP---------NNVCTGVLTRRGGICNGDGGTPLVC------EGLAHGVAS 216 +C +P N +C G+ + C GD G LV G+ S Sbjct: 312 HQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVS 371 Query: 217 FSLGPCGRGPDF--FTRVALFRDWIDGVLNN 245 + CG + +T+V + WI+ ++++ Sbjct: 372 WGSMNCGEAGQYGVYTKVINYIPWIENIISD 402 >1Q3X-A nrPDB Length = 328 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/248 (26%), Positives = 111/248 (44%), Gaps = 36/248 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I GG+KA+P FP+ I G GAL++ +V+TAA Q S + + L Sbjct: 87 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 144 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILPLPLQNA---- 141 +R Q +S + GY ND+ L++L+ + + S++T + LP + A Sbjct: 145 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 204 Query: 142 -TVEAGTRCQVAGWG-SQRSGGRLSRFPRFVNVTVTPEDQC-----RP---------NNV 185 T + GT +GWG +QR G L+R +V++ + +C +P N + Sbjct: 205 RTDDIGT---ASGWGLTQR--GFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANML 259 Query: 186 CTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFSLGPCGRGPDF--FTRVALFRD 237 C G+ + C GD G LV G+ S+ CG + +T+V + Sbjct: 260 CAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 319 Query: 238 WIDGVLNN 245 WI+ ++++ Sbjct: 320 WIENIISD 327 >1PQ7-A nrPDB Length = 224 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 67/230 (29%), Positives = 92/230 (40%), Gaps = 25/230 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG A FPF+ SI G +CGG+L++A V+TAA C VS + + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHC-------VSGYAQSGFQI 53 Query: 87 RRRERQSRQTFSISSMSENGYDPQQ--NLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 R SS+S P N NDL +L+L ++ L + Sbjct: 54 RAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIPSGGNIGYARLAASGSDPV 113 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRF-VNVTVTPEDQCRPNN---------VCTGVLTRRG 194 AG+ VAGWG+ GG + V V + CR C GV + Sbjct: 114 AGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGK 173 Query: 195 GICNGDGGTPLV-CEGLAHGVASFSLGPCGRGPDF---FTRVALFRDWID 240 C GD G P+V G S+ G C R P++ + V R +ID Sbjct: 174 DSCQGDSGGPIVDSSNTLIGAVSWGNG-CAR-PNYSGVYASVGALRSFID 221 >5KWM-A nrPDB Length = 230 Score = 70.9 bits (172), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 92/232 (39%), Gaps = 37/232 (15%) Query: 27 IVGGRKARPRQFPF-LASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGG A + PF +A + G+ FCGG L V+TAA C P VV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG--- 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE- 144 R S ++S ++ P+ D SV L P++ A +E Sbjct: 58 ---RTVMSSNEGTVSKVTNVWVHPEYQ---------DAAKGFDVSVLTLEAPVKEAPIEL 105 Query: 145 -----AG----TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------PNN-VCT 187 AG T + GWG+ GG+ + + V V +D C+ P+ VC Sbjct: 106 AKADDAGYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCA 165 Query: 188 GVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRD 237 GV C GD G P+V GV S+ G C R P + RV + D Sbjct: 166 GVPEGGVDTCQGDSGGPMVVNNKLIGVTSWGEG-CARPGKPGVYARVGAYYD 216 >2JET-B nrPDB Length = 128 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 18/137 (13%) Query: 30 GRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVST---VVLGAYD 85 G A P +P+ S+Q++ G HFCGG+LI +V+TAA C GV T VV G +D Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC------GVKTSDVVVAGEFD 54 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNL----NDLMLLQLDREANLTSSVTILPLPLQNA 141 + + ++ Q I+ + +N P+ N+ ND+ LL+L A + +V+ + LP + Sbjct: 55 -QGSDEENIQVLKIAQVFKN---PKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDD 110 Query: 142 TVEAGTRCQVAGWGSQR 158 GT C GWG + Sbjct: 111 DFPPGTVCATTGWGKTK 127 >3I77-A nrPDB Length = 230 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 30/229 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQ-SQNPGVSTVVLGAY 84 +VGG +A +FPF+ + N+ FCGGAL V+TAA C S N T G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 DL+ + + S + G+ + D L++L + N + L + T Sbjct: 61 DLQ--SSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPT------LKIATTTAY 112 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGG 195 VAGWG+ R GG R+ NV + CR ++ +C G GG Sbjct: 113 NQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAG-YPDTGG 171 Query: 196 I--CNGDGGTPL-----VCEGLAHGVASFSLGPCGR--GPDFFTRVALF 235 + C GD G P+ E + G+ S+ G C R P +T V+ F Sbjct: 172 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGYG-CARPGYPGVYTEVSTF 219 >1KIG-H nrPDB Length = 241 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 65/241 (26%), Positives = 99/241 (41%), Gaps = 31/241 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGGR + P+ A + N+ FCGG +++ +V+TAA C TV +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKR--FTVRVGDRN 58 Query: 86 LRRRE-----RQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + E + T S + YD D+ +L+L +V LP ++ Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYD-----FDIAVLRLKTPIRFRRNVAPACLPEKD 113 Query: 141 ---ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGV 189 AT+ V+G+G GRLS + + V C+ PN C G Sbjct: 114 WAEATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGY 173 Query: 190 LTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRGPDF--FTRVALFRDWIDGVL 243 T+ C GD G P V G+ S+ G C R F +T+V+ F WID ++ Sbjct: 174 DTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKFGVYTKVSNFLKWIDKIM 232 Query: 244 N 244 Sbjct: 233 K 233 >1FIW-A nrPDB Length = 290 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/247 (25%), Positives = 100/247 (40%), Gaps = 37/247 (14%) Query: 27 IVGGRKARPRQFPFLASIQ------NQGRHFCGGALIHARFVMTAASCFQSQNP------ 74 I+GG+ A +P++ S+Q N+ H CGG+L+++++++TAA CF+ + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 75 --GVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVT 132 G V G + Q R I + Y ND+ L+++ + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKI--IIHEKYSASSEANDIALMKITPPVTCGHFIG 118 Query: 133 ILPLP-LQNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQC---------- 180 LP + C VAGWG Q + R S + V + C Sbjct: 119 PGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRI 178 Query: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAH------GVASFSLGPCGRG--PDFFTRV 232 R NVC G + C GD G PL+C+ A G+ S+ +G C R P +T Sbjct: 179 RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVG-CARAKRPGVYTST 237 Query: 233 ALFRDWI 239 + +WI Sbjct: 238 WSYLNWI 244 >4DJZ-B nrPDB Length = 251 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 65/253 (25%), Positives = 109/253 (43%), Gaps = 44/253 (17%) Query: 27 IVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCF-QSQNPGVST------ 78 I GR A+ P++A + + G+ FCGG+L+ + +++TAA C QS +P T Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 79 -------VVLGAYDLRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSS 130 ++LG + R R ++ Q + + + YDP ND+ L++L L + Sbjct: 61 LSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAF 119 Query: 131 VTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRF---VNVTVTPEDQCRP----- 182 V +P+ L + G V+GWG Q L RFP + + + C+ Sbjct: 120 V--MPICLPEGPQQEGAMVIVSGWGKQ----FLQRFPETLMEIEIPIVDHSTCQKAYAPL 173 Query: 183 ------NNVCTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLG-PCGRGPDF--F 229 + +C G C GD G P+V G + V + S G CG+ + + Sbjct: 174 KKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVY 233 Query: 230 TRVALFRDWIDGV 242 + + +DWI V Sbjct: 234 SYIHHNKDWIQRV 246 >4IGD-A nrPDB Length = 406 Score = 67.4 bits (163), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 65/256 (25%), Positives = 110/256 (42%), Gaps = 44/256 (17%) Query: 24 LLDIVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCF-QSQNPGVST--- 78 + I GR A+ P++A + + G+ FCGG+L+ + +++TAA C QS +P T Sbjct: 153 MAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRD 212 Query: 79 ----------VVLGAYDLRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANL 127 ++LG + R R ++ Q + + + YDP ND+ L++L L Sbjct: 213 SDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVL 271 Query: 128 TSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRF---VNVTVTPEDQCRP-- 182 + V +P+ L + G V+GWG Q L RFP + + + C+ Sbjct: 272 NAFV--MPICLPEGPQQEGAMVIVSGWGKQ----FLQRFPETLMEIEIPIVDHSTCQKAY 325 Query: 183 ---------NNVCTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLG-PCGRGPDF 228 + +C G C GD G P+V G + V + S G CG+ + Sbjct: 326 APLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRY 385 Query: 229 --FTRVALFRDWIDGV 242 ++ + +DWI V Sbjct: 386 GVYSYIHHNKDWIQRV 401 >3BEU-A nrPDB Length = 224 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 30/226 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQ-SQNPGVSTVVLGAYD 85 +VGG +A +FPF+ + CGGAL V+TAA C S N T G D Sbjct: 1 VVGGTRAAQGEFPFMVRLS----MGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L+ + + S + G+ + D L++L + N + L + T Sbjct: 57 LQ--SSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPT------LKIATTTAYN 108 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGGI 196 VAGWG+ R GG R+ NV + CR ++ +C G T++ Sbjct: 109 QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDT 168 Query: 197 CNGDGGTPL-----VCEGLAHGVASFSLGPCGRGPDF--FTRVALF 235 C GD G P+ E + G+ S+ G C R + +T V+ F Sbjct: 169 CQGDSGGPMFRKDNADEWVQVGIVSWGEG-CARKGKYGVYTEVSTF 213 >5LHN-A nrPDB Length = 247 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 102/244 (41%), Gaps = 33/244 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGR------HFCGGALIHARFVMTAASCFQSQNPGVSTVV 80 IVGG P+ A+I + + CGG+LI +V +AA CF + VV Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGYDPQQNL---NDLMLLQLDRE----ANLTSSVTI 133 F + + + Y + +L ND+ LL++ A + S+ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 134 LPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP---EDQC-RPNN----- 184 + LP + G+ C++ G+G + L +P+ + ++V +QC +P+ Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYL--YPKNLKMSVVKLVSHEQCMQPHYYGSEI 178 Query: 185 ----VCTGVLTRRGGICNGDGGTPLVC--EG--LAHGVASFSLGPCGRG-PDFFTRVALF 235 +C + C GD G PL+C EG G+ S+ G + P +TRV+ F Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHF 238 Query: 236 RDWI 239 DWI Sbjct: 239 LDWI 242 >2QY0-B nrPDB Length = 242 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 31/239 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF-----QSQNPGVSTVVL 81 I+GG+KA+ FP+ GR GGAL+ R+++TAA ++Q+ V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 82 GAYDLRRRERQSRQTFS-ISSMSENGYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQ 139 G ++ + +S + D N D+ LL+L+ L ++ + LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 118 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------------PNNVC 186 + + G V+G+G +++ RFV + V C N C Sbjct: 119 DTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFC 176 Query: 187 TGVLTRRGGICNGDGG------TPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 G + + C GD G P +A G+ S+ +G C RG F+T+V + DWI Sbjct: 177 AGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIG-CSRGYGFYTKVLNYVDWI 234 >1SC8-U nrPDB Length = 262 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 61/247 (24%), Positives = 102/247 (41%), Gaps = 32/247 (12%) Query: 23 PLLDIVGGRKARPRQFPFLASIQNQGR-----HFCGGALIHARFVMTAASCFQSQNPGVS 77 P I+GG P+ A+I + R + CGG+LI +V++A CF Sbjct: 12 PRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKED 71 Query: 78 TVVLGAYDLRRRERQSRQTFSISSM---SENGYDPQQNLNDLMLLQLD----REANLTSS 130 +V Q F + ++ + D + ND+ LL++ R A + + Sbjct: 72 YIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRT 131 Query: 131 VTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP---EDQC-RPNNVC 186 + + LP + GT C++ G+G + S L +P + +TV +C +P+ Sbjct: 132 IQTISLPSMYNDPQFGTSCEITGFGKENSTDYL--YPEQLKMTVVKLISHRECQQPHYYG 189 Query: 187 TGVLTR---------RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG-PDFFTRV 232 + V T+ + C GD G PLVC G+ S+ G + P +TRV Sbjct: 190 SEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRV 249 Query: 233 ALFRDWI 239 + F WI Sbjct: 250 SHFLPWI 256 >1ETT-H nrPDB Length = 259 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF----QSQNPGVSTVV--LGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C +N V ++ +G + R ER+ + + + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYI 86 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNAT---VEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ LL+L R L+ + + LP + + AG + +V GWG++R Sbjct: 87 HPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRE 146 Query: 160 GGRLS------RFPRFVNVTVTPEDQCRP--------NNVCTGVLT---RRGGICNGDGG 202 S + VN+ + C+ N C G +RG C GD G Sbjct: 147 TWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSG 206 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 207 GPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDRLG 258 >1MKW-K nrPDB Length = 308 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF----QSQNPGVSTVV--LGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C +N V ++ +G + R ER+ + + + Sbjct: 76 LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYI 135 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNAT---VEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ LL+L R L+ + + LP + + AG + +V GWG++R Sbjct: 136 HPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRE 195 Query: 160 GGRLS------RFPRFVNVTVTPEDQCRP--------NNVCTGVLT---RRGGICNGDGG 202 S + VN+ + C+ N C G +RG C GD G Sbjct: 196 TWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSG 255 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 256 GPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDRLG 307 >1MD7-A nrPDB Length = 328 Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 31/239 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF-----QSQNPGVSTVVL 81 I+GG+KA+ FP+ GR GGAL+ R+++TAA ++Q+ V L Sbjct: 90 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 147 Query: 82 GAYDLRRRERQSRQTFS-ISSMSENGYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQ 139 G ++ + +S + D N D+ LL+L+ L ++ + LP Sbjct: 148 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 207 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------------PNNVC 186 + + G V+G+G +++ RFV + V C N C Sbjct: 208 DTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFC 265 Query: 187 TGVLTRRGGICNGDGG------TPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 G + + C GD G P +A G+ S+ +G C RG F+T+V + DWI Sbjct: 266 AGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIG-CSRGYGFYTKVLNYVDWI 323 >3H7O-A nrPDB Length = 228 Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 56/228 (24%), Positives = 97/228 (42%), Gaps = 13/228 (5%) Query: 29 GGRKARPRQFPFLASIQN---QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 GG K +Q P+ +++ + CGGA++ FV+TAA C Q P T+V+ Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKP--ETIVIQYES 59 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTS-SVTILPLPLQNATVE 144 E + +S + + Y + ND+ +L+L R L LP + Sbjct: 60 TNLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----PNNVCTGVL-TRRGGIC-- 197 G+ V+G+G ++ + +TV D+CR P + V ++ G+ Sbjct: 120 TGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLE 179 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 +GD G P V + GVA++ P+ FT+V + WI ++ Sbjct: 180 SGDAGDPTVQQDTLVGVAAYFPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >2XXL-A nrPDB Length = 408 Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 63/271 (23%), Positives = 109/271 (40%), Gaps = 55/271 (20%) Query: 27 IVGGRKARPRQFPFLASIQNQ----GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 + G + + P++A ++ Q R CGGA+I R+++TAA C + + LG Sbjct: 119 VSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRLG 178 Query: 83 AY------DLRRRERQSRQTFSI------SSMSENGYDPQQNLNDLMLLQLDREANLTSS 130 + D R++ R+ + + + YD + ++D+ LL+L+R Sbjct: 179 EHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQKH 238 Query: 131 VTILPLPLQNATVEAGTRCQ---VAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP----- 182 + + LP+ + E + V GWG+ +G S NV + P C Sbjct: 239 IKPICLPITDELKEKAEQISTYFVTGWGTTENGSS-SDVLLQANVPLQPRSACSQAYRRA 297 Query: 183 ---NNVCTGVLTRRGG----ICNGDGGTPLVC----------EGLAHGVASFSLGPCGRG 225 + +C G GG C GD G PL + + G+ S + CG+ Sbjct: 298 VPLSQLCVG-----GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQI 352 Query: 226 --PDFFTRVALFRDWI------DGVLNNPGP 248 P +T V + WI +G+L + GP Sbjct: 353 SLPGLYTNVGEYVQWITDTMASNGLLESRGP 383 >1GPZ-A nrPDB Length = 399 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 31/239 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF-----QSQNPGVSTVVL 81 I+GG+KA+ FP+ GR GGAL+ R+++TAA ++Q+ V L Sbjct: 158 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 215 Query: 82 GAYDLRRRERQSRQTFS-ISSMSENGYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQ 139 G ++ + +S + D N D+ LL+L+ L ++ + LP Sbjct: 216 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 275 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------------PNNVC 186 + + G V+G+G +++ RFV + V C N C Sbjct: 276 DTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFC 333 Query: 187 TGVLTRRGGICNGDGG------TPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 G + + C GD G P +A G+ S+ +G C RG F+T+V + DWI Sbjct: 334 AGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIG-CSRGYGFYTKVLNYVDWI 391 >2HLC-A nrPDB Length = 230 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 64/234 (27%), Positives = 103/234 (44%), Gaps = 33/234 (14%) Query: 27 IVGGRKARPRQFPFLA----SIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+ G +A FP+ A ++Q+Q R +CGG+LI ++++TAA C VS VV Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHD---AVSVVVYL 57 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLP----L 138 ++ + I +S + ++P LND+ L+++ T ++ + LP L Sbjct: 58 GSAVQYEGEAVVNSERI--ISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEEL 114 Query: 139 QNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGV 189 N V+GWG + + ++ + V D+C + +C G Sbjct: 115 NNKF--ENIWATVSGWGQSNTDTVILQYTYNL---VIDNDRCAQEYPPGIIVESTIC-GD 168 Query: 190 LTRRGGICNGDGGTPLVC--EGLAHGVASFSLGP-CGRG-PDFFTRVALFRDWI 239 + C GD G P V + L GV SF G C G P F+RV + DWI Sbjct: 169 TSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWI 222 >5O32-I nrPDB Length = 244 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 66/252 (26%), Positives = 104/252 (41%), Gaps = 47/252 (18%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG----VSTVVLG 82 IVGG++A+ P+ +I++ CGG I +++TAA C ++ +TVV Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 83 AY-DLRR--RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILP---- 135 + DL+R E R F EN Y+ ND+ L+++ ++ N LP Sbjct: 61 IHPDLKRIVIEYVDRIIF-----HEN-YNAGTYQNDIALIEMKKDGNKKDCE--LPRSIP 112 Query: 136 --LPLQNATVEAGTRCQVAGWGSQRSGGR-----------LSRFPRFVNVTVTPEDQCRP 182 +P + C V+GWG ++ R +S +F ++ Sbjct: 113 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEM--- 169 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRGPDF---FTRVAL 234 C G C GD G PLVC GV S+ CG+ P+F +T+VA Sbjct: 170 --ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGK-PEFPGVYTKVAN 225 Query: 235 FRDWIDGVLNNP 246 + DWI + P Sbjct: 226 YFDWISYHVGRP 237 >4Z6A-H nrPDB Length = 249 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 66/244 (27%), Positives = 100/244 (40%), Gaps = 24/244 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG+ + P+ + G CGG LI+ +V++AA CF +N VLG +D Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 86 LRRR--ERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLP---LQN 140 L + QSR+ + + + Y P +D+ LL+L + LT V L LP Sbjct: 61 LSEHDGDEQSRRVAQV--IIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSE 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---PNNV-----CTGVLTR 192 T+ V+GWG G + +NV C P + C G Sbjct: 119 RTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDG 178 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRGPDF--FTRVALFRDWIDGVL-NN 245 C GD G P G+ S+ G C F +TRV+ + +W+ ++ + Sbjct: 179 SKDSCKGDSGGPHATHYRGTWYLTGIVSWGQG-CATVGHFGVYTRVSQYIEWLQKLMRSE 237 Query: 246 PGPG 249 P PG Sbjct: 238 PRPG 241 >3H7T-A nrPDB Length = 235 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 62/243 (25%), Positives = 90/243 (37%), Gaps = 41/243 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG+K+ + P+ + + FCGG+++ A FV+TAA C P ++ G+ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS--- 57 Query: 87 RRRERQSRQTFSISSMSEN----GYDPQQNLNDLMLLQLDREANLTSSVT-ILPLPLQNA 141 R T S M++ Y P N+ +++ + L T + LP Sbjct: 58 -----SYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLY 112 Query: 142 TVEAGTRCQVAGWGS------QRSGGRLSRFPRFVNVTVTPEDQCRPNN----------- 184 E T V+GWGS + SG + N TV C Sbjct: 113 DPEPDTSVLVSGWGSTNFKSLEYSGDLME-----ANFTVVDRKSCEEQYKQIEADKYIYD 167 Query: 185 --VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALF----RDW 238 C G I GD G P V G GVAS+ P F RV + +D Sbjct: 168 GVFCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDI 227 Query: 239 IDG 241 I G Sbjct: 228 ISG 230 >2XRC-A nrPDB Length = 565 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 102/252 (40%), Gaps = 47/252 (18%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG----VSTVVLG 82 IVGG++A+ P+ +I++ CGG I +++TAA C ++ +TVV Sbjct: 322 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 381 Query: 83 AY-DLRR--RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILP---- 135 + DL+R E R F Y+ ND+ L+++ ++ N LP Sbjct: 382 IHPDLKRIVIEYVDRIIF------HENYNAGTYQNDIALIEMKKDGNKKDCE--LPRSIP 433 Query: 136 --LPLQNATVEAGTRCQVAGWGSQRSGGR-----------LSRFPRFVNVTVTPEDQCRP 182 +P + C V+GWG ++ R +S +F ++ Sbjct: 434 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEM--- 490 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRGPDF---FTRVAL 234 C G C GD G PLVC GV S+ CG+ P+F +T+VA Sbjct: 491 --ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGK-PEFPGVYTKVAN 546 Query: 235 FRDWIDGVLNNP 246 + DWI + P Sbjct: 547 YFDWISYHVGRP 558 >2FMJ-A nrPDB Length = 222 Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 62/227 (27%), Positives = 88/227 (38%), Gaps = 34/227 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGAYD 85 +VGG +A +FPF+ + CGGAL V+TAA C S T G D Sbjct: 1 VVGGTRAAQGEFPFMVRLS----MGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LRRRER-QSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 L+ + R T + + NG D L++L + N + L + T Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGTG-----KDWALIKLAQPINQPT------LKIATTTAY 105 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGVLTRRGG 195 VAGWG+ R GG R+ NV + CR +C G T Sbjct: 106 NQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVD 165 Query: 196 ICNGDGGTPL-----VCEGLAHGVASFSLGPCGRGPDF--FTRVALF 235 C GD G P+ E + G+ S+ G C R + +T V+ F Sbjct: 166 TCQGDSGGPMFRKDNADEWIQVGIVSWGEG-CARKGKYGVYTEVSTF 211 >2OCV-B nrPDB Length = 259 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/233 (24%), Positives = 97/233 (41%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 27 LCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYV 86 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNAT---VEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ LL+L + + + + LP + + AG + +V GWG+ R Sbjct: 87 HPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRE 146 Query: 160 GGRLS------RFPRFVNVTVTPEDQCRP--------NNVCTGVL---TRRGGICNGDGG 202 + + VN+ + C+ N C G T+RG C GD G Sbjct: 147 TWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSG 206 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 207 GPFVMKSPFNNRWYQMGIVSWGEG-CDRKGKYGFYTHVFRLKAWIQKVIDQFG 258 >1C5M-D nrPDB Length = 255 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 37/247 (14%) Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASC-FQSQNPGVSTVVLGAY 84 IVGG++ + + P+ A + N+ FCGG ++ +++TAA C +Q++ + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR----------F 50 Query: 85 DLRRRERQSRQTFSISSMSE-------NGYDPQQNLNDLMLLQLDREANLTSSVTILPLP 137 +R +R + Q ++ E N + + D+ +L+L +V LP Sbjct: 51 KVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLP 110 Query: 138 LQN---ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVC 186 ++ +T+ V+G+G GR S + + V + C+ N C Sbjct: 111 ERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFC 170 Query: 187 TGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRGPDF--FTRVALFRDWID 240 G T++ C GD G P V G+ S+ G C R + +T+V F WID Sbjct: 171 AGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKYGIYTKVTAFLKWID 229 Query: 241 GVLNNPG 247 + G Sbjct: 230 RSMKTRG 236 >4KKD-A nrPDB Length = 433 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 71/274 (25%), Positives = 111/274 (40%), Gaps = 53/274 (19%) Query: 17 SRAGSSPLLDIVGGRKARPRQFPFLASIQNQ-------GRHFCGGALIHARFVMTAASCF 69 SR+ S + I+GGR A P FP+ A I + + F GAL+ A +++TAA Sbjct: 145 SRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVL 204 Query: 70 QSQNPGVS---------TVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120 +SQ + TV LG +D+R + + + + + ++ Q +D+ L+Q Sbjct: 205 RSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPD-FNIQNYNHDIALVQ 263 Query: 121 LDREANLTSSVTILPLP-LQNATVEAGTRCQVAGWGSQR----------SGGR-LSRFPR 168 L L V + LP L+ VAGWG SG R LS + Sbjct: 264 LQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQ 323 Query: 169 FVNVTVTPEDQCR-------------PNNVCTGVLTRRGGICNGDGGTPLVC------EG 209 +V + V P +C+ N C G C GD G V Sbjct: 324 YVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRW 383 Query: 210 LAHGVASFSLGP--CGRGPDF--FTRVALFRDWI 239 + G+ S+ GP CG + +T+V+ + DW+ Sbjct: 384 VVQGLVSWG-GPEECGSKQVYGVYTKVSNYVDWV 416 >4IW4-E nrPDB Length = 279 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 106/264 (40%), Gaps = 53/264 (20%) Query: 27 IVGGRKARPRQFPFLASIQNQ-------GRHFCGGALIHARFVMTAASCFQSQNPGVS-- 77 I+GGR A P FP+ A I + + F GAL+ A +++TAA +SQ + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 78 -------TVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSS 130 TV LG +D+R + + + + + ++ Q +D+ L+QL L Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPD-FNIQNYNHDIALVQLQEPVPLGPH 119 Query: 131 VTILPLP-LQNATVEAGTRCQVAGWGSQR----------SGGR-LSRFPRFVNVTVTPED 178 V + LP L+ VAGWG SG R LS ++V + V P Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 179 QCR-------------PNNVCTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFSL 219 +C+ N C G C GD G V + G+ S+ Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWG- 238 Query: 220 GP--CGRGPDF--FTRVALFRDWI 239 GP CG + +T+V+ + DW+ Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWV 262 >3K65-B nrPDB Length = 308 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 98/233 (42%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 76 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 135 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ L++L + + + + LP + + ++AG + +V GWG+ + Sbjct: 136 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 195 Query: 160 ------GGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLT---RRGGICNGDGG 202 G + VN+ + C+ N C G +RG C GD G Sbjct: 196 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAG 255 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 256 GPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDQFG 307 >3NXP-A nrPDB Length = 424 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 98/233 (42%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 192 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 251 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ L++L + + + + LP + + ++AG + +V GWG+ + Sbjct: 252 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 311 Query: 160 ------GGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLT---RRGGICNGDGG 202 G + VN+ + C+ N C G +RG C GD G Sbjct: 312 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSG 371 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 372 GPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDQFG 423 >4NZQ-A nrPDB Length = 557 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 97/233 (41%), Gaps = 37/233 (15%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 325 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 384 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNAT---VEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ L++L + + + + LP + ++AG + +V GWG+ + Sbjct: 385 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 444 Query: 160 ------GGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLT---RRGGICNGDGG 202 G + VN+ + C+ N C G +RG C GD G Sbjct: 445 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSG 504 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLNNPG 247 P V + G+ S+ G C R F+T V + WI V++ G Sbjct: 505 GPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDQFG 556 >1VR1-H nrPDB Length = 261 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 37/232 (15%) Query: 49 RHFCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSM 102 R CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 29 RFLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKI 88 Query: 103 SEN-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQ 157 + Y+ ++NL+ D+ L++L + + + + LP + + ++AG + +V GWG+ Sbjct: 89 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 148 Query: 158 RS------GGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLT---RRGGICNGD 200 + G + VN+ + C+ N C +RG C GD Sbjct: 149 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGD 208 Query: 201 GGTPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLN 244 G P V + G+ S+ G C R F+T V + WI V++ Sbjct: 209 SGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVID 259 >5TO3-B nrPDB Length = 409 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 96/230 (41%), Gaps = 37/230 (16%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 86 Query: 105 NG-YDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ L++L + + + + LP + + ++AG + +V GWG+ + Sbjct: 87 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 146 Query: 160 ------GGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLT---RRGGICNGDGG 202 G + VN+ + C+ N C G +RG C GD G Sbjct: 147 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSG 206 Query: 203 TPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLN 244 P V + G+ S G C R F+T V + WI V++ Sbjct: 207 GPFVMKSPFNNRWYQMGIVSAGAG-CDRDGKYGFYTHVFRLKKWIQKVID 255 >4BXW-A nrPDB Length = 423 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 101/264 (38%), Gaps = 30/264 (11%) Query: 11 AGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCF 69 A LL S SP + IV G + + P+ A++ ++ FCGG ++ +V+TAA C Sbjct: 155 ATLLKKSD-NPSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCI 213 Query: 70 QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLN--------DLMLLQL 121 +VV+G D R E + + + PQ+ D+ ++Q+ Sbjct: 214 NETE--TISVVVGEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQM 271 Query: 122 DREANLTSSVTILPLP---LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNV------ 172 + +V LP N + V+G+G G S+ + + V Sbjct: 272 KTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRH 331 Query: 173 --TVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLGPCGRGP 226 V+ E PN C G T C GD G P G+ S G C R Sbjct: 332 TCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEG-CARNG 390 Query: 227 DF--FTRVALFRDWIDGVLNNPGP 248 + +T+++ F WI ++ P Sbjct: 391 KYGNYTKLSKFIPWIKRIMRQKLP 414 >1BBR-H nrPDB Length = 150 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 11/120 (9%) Query: 51 FCGGALIHARFVMTAASCF----QSQNPGVSTVV--LGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C +N V ++ +G + R ER+ + + + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYI 86 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNAT---VEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ LL+L R L+ + + LP + + AG + +V GWG++R Sbjct: 87 HPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRE 146 >5UBM-A nrPDB Length = 252 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 56/246 (22%), Positives = 96/246 (39%), Gaps = 41/246 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG A + FP+ N + GGALI+ +V+TAA + T+ +G+ + Sbjct: 2 IIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNRE--PTMYVGSTSV 56 Query: 87 R-RRERQSRQTFSISSMSENGY------DPQQNL-NDLMLLQLDREANLTSSVTILPLP- 137 + R +S+ G+ + + N ND+ L++L + +V+ + LP Sbjct: 57 QTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPG 116 Query: 138 -LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------------- 181 + + G ++GWG R R + + V P +C+ Sbjct: 117 TSSDYNLMDGDLGLISGWGRTEKRDRAVRL-KAARLPVAPLRKCKEVKVEKPTADAEAYV 175 Query: 182 --PNNVCTGVLTRRG-GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD-----FFTRVA 233 PN +C G +G C GD G + ++ G GP +TRV Sbjct: 176 FTPNMICAG--GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVK 233 Query: 234 LFRDWI 239 + DWI Sbjct: 234 NYVDWI 239 >1ELV-A nrPDB Length = 333 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/246 (22%), Positives = 96/246 (39%), Gaps = 41/246 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG A + FP+ N + GGALI+ +V+TAA + T+ +G+ + Sbjct: 83 IIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNRE--PTMYVGSTSV 137 Query: 87 R-RRERQSRQTFSISSMSENGY------DPQQNL-NDLMLLQLDREANLTSSVTILPLP- 137 + R +S+ G+ + + N ND+ L++L + +V+ + LP Sbjct: 138 QTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPG 197 Query: 138 -LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------------- 181 + + G ++GWG R R + + V P +C+ Sbjct: 198 TSSDYNLMDGDLGLISGWGRTEKRDRAVRL-KAARLPVAPLRKCKEVKVEKPTADAEAYV 256 Query: 182 --PNNVCTGVLTRRG-GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD-----FFTRVA 233 PN +C G +G C GD G + ++ G GP +TRV Sbjct: 257 FTPNMICAG--GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVK 314 Query: 234 LFRDWI 239 + DWI Sbjct: 315 NYVDWI 320 >4J1Y-A nrPDB Length = 397 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 55/245 (22%), Positives = 95/245 (38%), Gaps = 41/245 (16%) Query: 28 VGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLR 87 +GG A + FP+ N + GGALI+ +V+TAA + T+ +G+ ++ Sbjct: 148 IGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNRE--PTMYVGSTSVQ 202 Query: 88 -RRERQSRQTFSISSMSENGY------DPQQNL-NDLMLLQLDREANLTSSVTILPLP-- 137 R +S+ G+ + + N ND+ L++L + +V+ + LP Sbjct: 203 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 262 Query: 138 LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------------- 181 + + G ++GWG R R + + V P +C+ Sbjct: 263 SSDYNLMDGDLGLISGWGRTEKRDRAVRL-KAARLPVAPLRKCKEVKVEKPTADAEAYVF 321 Query: 182 -PNNVCTGVLTRRG-GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD-----FFTRVAL 234 PN +C G +G C GD G + ++ G GP +TRV Sbjct: 322 TPNMICAG--GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKN 379 Query: 235 FRDWI 239 + DWI Sbjct: 380 YVDWI 384 >1AKS-B nrPDB Length = 98 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWID 240 N +C G L C GD G P+VC G G+ S+ G + P +T+V + +WI Sbjct: 34 NMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQ 92 >1RIW-B nrPDB Length = 147 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 11/120 (9%) Query: 51 FCGGALIHARFVMTAASCF------QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE 104 CG +LI R+V+TAA C ++ V +G + R ER + + + Sbjct: 27 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 86 Query: 105 N-GYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQRS 159 + Y+ ++NL+ D+ L++L + + + + LP + + ++AG + +V GWG+ + Sbjct: 87 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 146 >1EPT-B nrPDB Length = 82 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Query: 114 NDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQR 158 ND+ML++L A L S V + LP A AGT C ++GWG+ + Sbjct: 40 NDIMLIKLSSPATLNSRVATVSLPRSCAA--AGTECLISGWGNTK 82 >2KAI-A nrPDB Length = 80 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GGR+ P+ +I + CGG L++ ++V+TAA C ++ N V LG ++L Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC-KNDN---YEVWLGRHNL 56 Query: 87 RRRERQSRQTFSISS 101 E + Q F +++ Sbjct: 57 FENENTA-QFFGVTA 70 >3F1S-B nrPDB Length = 283 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Query: 36 RQFPFLASIQN-QGRHFCGGALIHARFVMTAASC-FQSQNPGVSTVVLGAYDLRRRERQS 93 + P+ + N +G+ FCGG +I FV+T A C +N V T R Q Sbjct: 62 QDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYF-------NRTSQD 114 Query: 94 RQTFSISSMSENG-YDPQQNLNDLMLLQLD 122 I+ + + YD NDL LL+L+ Sbjct: 115 PLMIKITHVHVHMRYDADAGENDLSLLELE 144 >3H5C-B nrPDB Length = 317 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Query: 36 RQFPFLASIQN-QGRHFCGGALIHARFVMTAASC-FQSQNPGVSTVVLGAYDLRRRERQS 93 + P+ + N +G+ FCGG +I FV+T A C +N V T R Q Sbjct: 103 QDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYF-------NRTSQD 155 Query: 94 RQTFSISSMSENG-YDPQQNLNDLMLLQLD 122 I+ + + YD NDL LL+L+ Sbjct: 156 PLMIKITHVHVHMRYDADAGENDLSLLELE 185 >4F4O-C nrPDB Length = 347 Score = 36.6 bits (83), Expect = 0.011, Method: Compositional matrix adjust. Identities = 47/244 (19%), Positives = 89/244 (36%), Gaps = 37/244 (15%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG FP+ A + + G LI+ ++++T A + + + A L Sbjct: 103 IMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAPTL 162 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R + +Q I + + P + D+ L++L ++ + V + LP ++ V G Sbjct: 163 RLYVGK-KQEVEIEKVI---FHPDNSTVDIGLIKLKQKVPVNERVMPICLPSKDY-VNVG 217 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------------------------R 181 V+GWG + + + ++V + V +++C Sbjct: 218 LVGYVSGWG-RNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILN 276 Query: 182 PNNVCTGVLTRRGGICNGDGGTPLVCEG------LAHGVASFSLGPCGRGPDFFTRVALF 235 + C G+ + C GD G+ A G+ SF + RV Sbjct: 277 EHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEYGVYVRVTSI 336 Query: 236 RDWI 239 DWI Sbjct: 337 LDWI 340 >2OK5-A nrPDB Length = 752 Score = 35.0 bits (79), Expect = 0.028, Method: Compositional matrix adjust. Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 12/139 (8%) Query: 10 LAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF 69 L G++ R G+ +P Q ++G C GA++ FV+TAA CF Sbjct: 462 LCGMVWEHRKGTD--------YHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF 513 Query: 70 QSQNPGVSTVVLGAYDLRRRERQS---RQTFSISSMSENGYDPQQNLNDLMLLQLDREAN 126 + S V + R E + ++I+ E G P+ D+ L++L + Sbjct: 514 TVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI-PEFYDYDVALIKLKNKLK 572 Query: 127 LTSSVTILPLPLQNATVEA 145 ++ + LP T A Sbjct: 573 YGQTIRPICLPCTEGTTRA 591 >1DLE-A nrPDB Length = 298 Score = 34.7 bits (78), Expect = 0.042, Method: Compositional matrix adjust. Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 12/139 (8%) Query: 10 LAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF 69 L G++ R G+ +P Q ++G C GA++ FV+TAA CF Sbjct: 11 LCGMVWEHRKGTD--------YHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF 62 Query: 70 QSQNPGVSTVVLGAYDLRRRERQS---RQTFSISSMSENGYDPQQNLNDLMLLQLDREAN 126 + S V + R E + ++I+ E G P+ D+ L++L + Sbjct: 63 TVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI-PEFYDYDVALIKLKNKLK 121 Query: 127 LTSSVTILPLPLQNATVEA 145 ++ + LP T A Sbjct: 122 YGQTIRPICLPCTEGTTRA 140 >2WIN-I nrPDB Length = 507 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 17/149 (11%) Query: 10 LAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF 69 L G++ R G+ +P Q ++G C GA++ FV+TAA CF Sbjct: 218 LCGMVWEHRKGTD--------YHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF 269 Query: 70 QSQNPGVSTVVLGAYDLRRRERQS---RQTFSISSMSENGYDPQQNLNDLMLLQLDREAN 126 + S V + R E + ++I+ E G P+ D+ L++L + Sbjct: 270 TVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI-PEFYDYDVALIKLKNKLK 328 Query: 127 LTSSVTILPLPLQNATVEA-----GTRCQ 150 ++ + LP T A T CQ Sbjct: 329 YGQTIRPICLPCTEGTTRALRLPPTTTCQ 357 >2I6S-A nrPDB Length = 517 Score = 33.5 bits (75), Expect = 0.088, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 23/35 (65%) Query: 39 PFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN 73 P+ +I+ + + C GALI ++V+TAA CF+ N Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGN 278 >2JET-C nrPDB Length = 99 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 197 CNGDGGTPLVCE----GLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVLN 244 C GD G PLVC+ G+ S+ G C P ++RV W+ +L Sbjct: 45 CMGDSGGPLVCQKDGVWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILE 97 >1BBR-E nrPDB Length = 109 Score = 30.0 bits (66), Expect = 0.97, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 192 RRGGICNGDGGTPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVL 243 +RG C GD G P V + G+ S+ G C R F+T V + WI V+ Sbjct: 46 KRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 104 Query: 244 NNPG 247 + G Sbjct: 105 DRLG 108 >2HNT-F nrPDB Length = 105 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 192 RRGGICNGDGGTPLVCEG------LAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVL 243 +RG C GD G P V + G+ S+ G C R F+T V + WI V+ Sbjct: 42 KRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 100 Query: 244 NNPG 247 + G Sbjct: 101 DQFG 104 >1UP3-A nrPDB Length = 294 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 13/90 (14%) Query: 168 RFVNVTVTPE----DQCRPNNVCTGVLTRRGGICNGDGGTP-LVCEGLAH-GVASFSLGP 221 +V TP+ DQ P G + R G G P L G+ H S++ G Sbjct: 31 ELTSVANTPQSYWLDQAFPPATVGGTVARYTGAAQAAGAMPVLTLYGIPHRDCGSYASGG 90 Query: 222 CGRGPDFFTRVALFRDWIDGVLNNPGPGPA 251 G D+ R WID V + G PA Sbjct: 91 FATGTDY-------RGWIDAVASGLGSSPA 113 >3RU4-E nrPDB Length = 96 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 197 CNGDGGTPLVCEGLAH----GVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 C GD G PLVC+ G+ S+ C P + RV +W+ L Sbjct: 42 CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >5F2K-A nrPDB Length = 368 Score = 26.9 bits (58), Expect = 7.5, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 121 LDREANL-TSSVTILPLPLQNATVEAGTRCQVAG 153 + RE L SSV + P P+++AT +R Q AG Sbjct: 1 MPREIRLPESSVVVRPAPMESATYSQSSRLQAAG 34 >5EJ2-A nrPDB Length = 308 Score = 26.6 bits (57), Expect = 9.9, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 5 TVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLAS 43 TV A + +L+ R GS L VGGRKA P ++A+ Sbjct: 165 TVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAA 203 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AE5-A nrPDB 322 1e-88 5FXL-A nrPDB 295 1e-80 1UTJ-A nrPDB 292 8e-80 1F7Z-A nrPDB 290 3e-79 4AN7-A nrPDB 290 5e-79 4WWY-A nrPDB 285 1e-77 1A0J-A nrPDB 284 2e-77 5C67-A nrPDB 283 5e-77 1FI8-A nrPDB 280 4e-76 1EUF-A nrPDB 279 1e-75 5TJX-A nrPDB 275 1e-74 6I44-A nrPDB 275 1e-74 3T2N-A nrPDB 274 3e-74 5GVT-A nrPDB 274 3e-74 1FUJ-A nrPDB 273 6e-74 1SGF-G nrPDB 270 3e-73 2TLD-E nrPDB 270 3e-73 1IAU-A nrPDB 269 7e-73 4NFE-A nrPDB 268 1e-72 1NN6-A nrPDB 265 1e-71 3W94-A nrPDB 265 1e-71 1P57-B nrPDB 264 3e-71 2EEK-A nrPDB 264 3e-71 5MS3-A nrPDB 263 4e-71 1FXY-A nrPDB 263 6e-71 2F83-A nrPDB 262 8e-71 1FDP-A nrPDB 262 1e-70 1SPJ-A nrPDB 262 1e-70 4DGJ-A nrPDB 261 2e-70 3G01-A nrPDB 260 3e-70 1NPM-A nrPDB 259 6e-70 1EKB-B nrPDB 259 9e-70 3TK9-A nrPDB 258 2e-69 3QUM-P nrPDB 258 2e-69 1X7A-C nrPDB 258 2e-69 5UGG-A nrPDB 257 3e-69 3BSQ-A nrPDB 257 5e-69 4DUR-A nrPDB 256 5e-69 3LC3-A nrPDB 255 1e-68 3RP2-A nrPDB 254 3e-68 6QHB-A nrPDB 254 3e-68 5FCR-A nrPDB 253 4e-68 3E0N-B nrPDB 253 4e-68 1AO5-A nrPDB 253 5e-68 1KIG-H nrPDB 253 5e-68 1TON-A nrPDB 253 7e-68 3DFJ-A nrPDB 252 8e-68 6AOD-C nrPDB 252 1e-67 1BRU-P nrPDB 252 1e-67 5ZFH-A nrPDB 251 2e-67 1ORF-A nrPDB 250 5e-67 3P8G-A nrPDB 248 2e-66 4H4F-A nrPDB 247 3e-66 2CGA-A nrPDB 247 3e-66 2RDL-A nrPDB 247 5e-66 1KYN-A nrPDB 247 5e-66 1C5M-D nrPDB 247 5e-66 2PSX-A nrPDB 245 1e-65 1MZD-A nrPDB 245 1e-65 1PPF-E nrPDB 245 2e-65 4Q7Y-A nrPDB 244 2e-65 2F91-A nrPDB 243 4e-65 1Q3X-A nrPDB 243 4e-65 4Z6A-H nrPDB 243 5e-65 1GVZ-A nrPDB 243 5e-65 2AIQ-A nrPDB 243 6e-65 1SGF-A nrPDB 243 6e-65 3K65-B nrPDB 242 1e-64 1BDA-A nrPDB 242 1e-64 3NXP-A nrPDB 241 2e-64 1PYT-D nrPDB 241 2e-64 1MKW-K nrPDB 241 2e-64 1ZJK-A nrPDB 240 3e-64 4NZQ-A nrPDB 240 5e-64 4GSO-A nrPDB 239 8e-64 2BDH-A nrPDB 239 9e-64 4MPW-A nrPDB 239 1e-63 2OCV-B nrPDB 238 1e-63 3F6U-H nrPDB 238 2e-63 2V35-A nrPDB 237 3e-63 1A5I-A nrPDB 236 6e-63 1YC0-A nrPDB 235 1e-62 2OQ5-A nrPDB 235 1e-62 1ETT-H nrPDB 235 2e-62 2ZKS-A nrPDB 234 2e-62 1ELT-A nrPDB 234 3e-62 4E7N-A nrPDB 234 3e-62 1LTO-A nrPDB 233 6e-62 1VR1-H nrPDB 233 7e-62 3S9B-A nrPDB 232 8e-62 2R0L-A nrPDB 232 1e-61 1AZZ-A nrPDB 231 2e-61 1OP0-A nrPDB 231 2e-61 4XDE-A nrPDB 231 3e-61 1FIZ-A nrPDB 230 3e-61 3S69-A nrPDB 228 2e-60 4BXW-A nrPDB 228 2e-60 4KKD-A nrPDB 227 3e-60 1BQY-A nrPDB 226 6e-60 1FIW-A nrPDB 226 7e-60 4FXG-H nrPDB 226 7e-60 1SC8-U nrPDB 224 3e-59 1EQ9-A nrPDB 224 3e-59 4IGD-A nrPDB 223 4e-59 1FON-A nrPDB 223 7e-59 5TO3-B nrPDB 221 2e-58 5LHN-A nrPDB 220 5e-58 2XXL-A nrPDB 217 3e-57 4IW4-E nrPDB 216 5e-57 1YM0-A nrPDB 216 6e-57 1GPZ-A nrPDB 216 9e-57 5LPF-A nrPDB 216 1e-56 1MD7-A nrPDB 215 2e-56 2QY0-B nrPDB 214 2e-56 2XRC-A nrPDB 211 1e-55 4DJZ-B nrPDB 211 3e-55 5XRF-A nrPDB 210 5e-55 5O32-I nrPDB 208 2e-54 4LK4-A nrPDB 208 3e-54 2OLG-A nrPDB 207 4e-54 5KWM-A nrPDB 207 4e-54 6BQM-A nrPDB 206 7e-54 2B9L-A nrPDB 206 8e-54 1ELV-A nrPDB 204 3e-53 5UBM-A nrPDB 203 8e-53 3I77-A nrPDB 202 1e-52 4J1Y-A nrPDB 198 2e-51 3BEU-A nrPDB 198 2e-51 1PQ7-A nrPDB 193 5e-50 1SI5-H nrPDB 193 7e-50 2ASU-B nrPDB 191 3e-49 2FMJ-A nrPDB 188 1e-48 3H7O-A nrPDB 188 1e-48 3H7T-A nrPDB 184 3e-47 2HLC-A nrPDB 178 2e-45 1M9U-A nrPDB 176 8e-45 5XW8-A nrPDB 175 1e-44 2PKA-B nrPDB 167 4e-42 3VGC-B nrPDB 162 1e-40 2JET-B nrPDB 155 2e-38 1RIW-B nrPDB 151 3e-37 1BBR-H nrPDB 148 2e-36 1AKS-B nrPDB 123 9e-29 1EPT-B nrPDB 102 1e-22 Sequences not found previously or not previously below threshold: 4WJG-C nrPDB 158 2e-39 4X0L-C nrPDB 154 2e-38 4F4O-C nrPDB 151 3e-37 2KAI-A nrPDB 111 2e-25 2WIN-I nrPDB 110 6e-25 1DLE-A nrPDB 107 3e-24 2I6S-A nrPDB 107 5e-24 2OK5-A nrPDB 106 9e-24 2HNT-F nrPDB 99 1e-21 1BBR-E nrPDB 98 4e-21 2JET-C nrPDB 92 2e-19 3RU4-E nrPDB 91 4e-19 3F1S-B nrPDB 91 6e-19 3H5C-B nrPDB 88 3e-18 2HNT-C nrPDB 76 1e-14 2HNT-E nrPDB 74 4e-14 1P3E-A nrPDB 43 1e-04 2OUA-A nrPDB 37 0.006 2EA3-A nrPDB 36 0.015 2PFE-A nrPDB 36 0.015 1DUE-A nrPDB 34 0.075 2SFA-A nrPDB 33 0.10 3LT3-A nrPDB 32 0.24 2SGA-A nrPDB 32 0.30 5OJX-A nrPDB 31 0.65 4NWK-A nrPDB 31 0.73 5XIG-A nrPDB 30 1.2 5XIP-A nrPDB 29 2.0 4NCX-A nrPDB 29 2.0 4FVB-A nrPDB 29 2.0 3W95-A nrPDB 29 2.1 4XZB-A nrPDB 29 2.3 4NSY-A nrPDB 29 2.4 2HRV-A nrPDB 29 2.5 1HPG-A nrPDB 28 3.5 2M5T-A nrPDB 28 4.5 5ILB-A nrPDB 27 5.1 4FLN-A nrPDB 27 5.1 4B6E-A nrPDB 27 5.7 6FE6-A nrPDB 27 9.0 5X88-A nrPDB 27 9.2 4U01-A nrPDB 27 9.6 >1AE5-A nrPDB Length = 225 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 225/225 (100%), Positives = 225/225 (100%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 206 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 180 Query: 207 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA 251 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA Sbjct: 181 CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA 225 >5FXL-A nrPDB Length = 246 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 116/255 (45%), Gaps = 20/255 (7%) Query: 1 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR 60 M LALL +A IVGG P+ S+ N G HFCGG+LI+++ Sbjct: 1 MKTFIFLALLGAAVAFPVDD---DDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQ 56 Query: 61 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120 +V++AA C++S V LG ++ E + + S+ Y+ ND+ML++ Sbjct: 57 WVVSAAHCYKS----GIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIK 112 Query: 121 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQ 179 L A+L S V + LP + AGT+C ++GWG+ +S G + + + + Sbjct: 113 LKSAASLNSRVASISLPT--SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSS 170 Query: 180 CRP--------NNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR-GPDFFT 230 C+ N C G L C GD G P+VC G G+ S+ G + P +T Sbjct: 171 CKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYT 230 Query: 231 RVALFRDWIDGVLNN 245 +V + WI + + Sbjct: 231 KVCNYVSWIKQTIAS 245 >1UTJ-A nrPDB Length = 242 Score = 292 bits (748), Expect = 8e-80, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 116/254 (45%), Gaps = 22/254 (8%) Query: 1 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR 60 M L + L+ A+ IVGG + +P P S+ N G HFCGG+L++ Sbjct: 1 MISLVFVLLIGAAFATED------DKIVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNEN 53 Query: 61 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120 +V++AA C++S+ V LG ++++ E + S + Y ND+ML++ Sbjct: 54 WVVSAAHCYKSR----VEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIK 109 Query: 121 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC 180 L + A L + V + LP + AGT C V+GWG+ S S + +N+ + C Sbjct: 110 LSKPATLNTYVQPVALPT--SCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDC 167 Query: 181 RPN--------NVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTR 231 + C G L C GD G P+VC G GV S+ G G P + + Sbjct: 168 NNSYPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAK 227 Query: 232 VALFRDWIDGVLNN 245 V +F DW+ + + Sbjct: 228 VCIFNDWLTSTMAS 241 >1F7Z-A nrPDB Length = 233 Score = 290 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 67/230 (29%), Positives = 110/230 (47%), Gaps = 17/230 (7%) Query: 24 LLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG + P+ S+ N G HFCGG+LI+ ++V++AA C++S+ V LG Sbjct: 8 DDAIVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKSR----IQVRLGE 62 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++ E + + + +D + ND+ML++L L + V + LP ++ Sbjct: 63 HNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALP--SSCA 120 Query: 144 EAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRG 194 AGT+C ++GWG+ S G + ++ + P+ C N VC G L Sbjct: 121 PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGK 180 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPC-GRGPDFFTRVALFRDWIDGVL 243 C GD G P+VC G G+ S+ G P +T+V + DWI + Sbjct: 181 DSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTI 230 >4AN7-A nrPDB Length = 231 Score = 290 bits (742), Expect = 5e-79, Method: Composition-based stats. Identities = 66/230 (28%), Positives = 110/230 (47%), Gaps = 17/230 (7%) Query: 24 LLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S+ V LG Sbjct: 6 DDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGE 60 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++ E + + ++ ++ ND+ML++L A L S V + LP + Sbjct: 61 HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SCA 118 Query: 144 EAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRG 194 AGT C ++GWG+ +S G + + V + C+ N +C G L Sbjct: 119 AAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGK 178 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 C GD G P+VC G G+ S+ G + P +T+V + +WI + Sbjct: 179 DSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 228 >4WWY-A nrPDB Length = 224 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 65/227 (28%), Positives = 106/227 (46%), Gaps = 17/227 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI+ ++V++A C++S+ V LG +++ Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + + YD + ND+ML++L A + + V+ + LP A G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPT--APPATG 113 Query: 147 TRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGGIC 197 T+C ++GWG+ S G + ++ V + +C N C G L C Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 D G P+VC G GV S+ G + P +T+V + WI + Sbjct: 174 QRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >1A0J-A nrPDB Length = 223 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 71/229 (31%), Positives = 115/229 (50%), Gaps = 17/229 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + R + AS+Q G HFCGG+LI + +V++AA C++S+ V LG +++ Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + S+ + Y+ + ND+ML++L + A+L S V+ + LP ++ +G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALP--SSCASSG 113 Query: 147 TRCQVAGWGSQR-SGGRLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGIC 197 TRC V+GWG+ S R +++ + C N C G + C Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVLNN 245 GD G P+VC G GV S+ G R P +T+V +R WI +++ Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSS 222 >5C67-A nrPDB Length = 224 Score = 283 bits (724), Expect = 5e-77, Method: Composition-based stats. Identities = 65/227 (28%), Positives = 108/227 (47%), Gaps = 17/227 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI ++V++AA C++++ V LG +++ Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYKTR----IQVRLGEHNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 + E + + + Y+ ND+ML++L A + + V+ + LP A AG Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT--APPAAG 113 Query: 147 TRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGIC 197 T C ++GWG+ S G + ++ V + +C+ + C G L C Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 D G P+VC G GV S+ G + P +T+V + DWI + Sbjct: 174 QRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >1FI8-A nrPDB Length = 228 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 18/232 (7%) Query: 27 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG +A+P P++A +Q G CGG LI FV+TAA C S+ V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK----IQVTLG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A++++ +E+ + + + Y+ + ND+MLL+L +A +S+V L LP +N Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRR 193 V+ G C VAGWG G+ S + V +TV + +C + N +C G + Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G PLVC+ +A G+ S+ G P FT+V+ F WI + Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYGQND-GSTPRAFTKVSTFLSWIKKTMKK 227 >1EUF-A nrPDB Length = 227 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 74/230 (32%), Positives = 115/230 (50%), Gaps = 16/230 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A + + H CGG L+ FV+TAA C S V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSS----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++ RER + + Y+ + ND+MLL+L R+A++T V+ + LP A V Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGG 195 + G C VAGWG + + V++ V E++C +C G ++R Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKN 176 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 +GD G PLVC G+A G+ S+ G PD +TR++ F WI + Sbjct: 177 SFSGDSGGPLVCNGVAQGIVSYGRND-GTTPDVYTRISSFLSWIHSTMRR 225 >5TJX-A nrPDB Length = 263 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 64/233 (27%), Positives = 102/233 (43%), Gaps = 20/233 (8%) Query: 26 DIVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVL 81 IVGG ++ ++P+ S+Q + RH CGG+LI ++V+TAA CF V + Sbjct: 15 RIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 74 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 G +L + + + + Y + +D+ L++L T + LP + Sbjct: 75 GILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKGD 134 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGVLTR 192 T T C V GWG + G + + VN+ + ++C+ VC G Sbjct: 135 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 194 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVALFRDWI 239 C GD G PLVC+ G+ S+ G C R P +T+VA + DWI Sbjct: 195 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWI 246 >6I44-A nrPDB Length = 627 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 64/233 (27%), Positives = 100/233 (42%), Gaps = 20/233 (8%) Query: 26 DIVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVL 81 IVGG ++ ++P+ S+Q + RH CGG+LI ++V+TAA CF V + Sbjct: 379 RIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 438 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 G L + + + + Y + +D+ L++L T + LP + Sbjct: 439 GILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSKGD 498 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGVLTR 192 T T C V GWG G + + VN+ + ++C+ VC G Sbjct: 499 TSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 558 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVALFRDWI 239 C GD G PLVC+ G+ S+ G C R P +T+VA + DWI Sbjct: 559 GKDACKGDAGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWI 610 >3T2N-A nrPDB Length = 372 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 109/260 (41%), Gaps = 25/260 (9%) Query: 10 LAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCF 69 LA + P+ IVGGR ++P+ S++ G H CGG+L+ +V+TAA CF Sbjct: 101 LAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCF 160 Query: 70 QSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGY------DPQQNLNDLMLLQLDR 123 +N +S + A + + Q + + GY + ++N ND+ L+ L Sbjct: 161 PERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSS 220 Query: 124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--- 180 LT + + LP + G C V GWG+ + G+ + + V + D C Sbjct: 221 PLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGA 280 Query: 181 -------RPNNVCTGVLTRRGGICNGDGGTPLVCE--------GLAHGVASFSLGPC-GR 224 +P C G C GD G P VCE G+ S+ G + Sbjct: 281 DFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQ 340 Query: 225 GPDFFTRVALFRDWIDGVLN 244 P +T+V+ FR+WI + Sbjct: 341 KPGVYTKVSDFREWIFQAIK 360 >5GVT-A nrPDB Length = 250 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 62/232 (26%), Positives = 98/232 (42%), Gaps = 20/232 (8%) Query: 27 IVGGRKARPRQFPFLASIQN---QGRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVLG 82 IVGG A ++P+ S+Q H CGG++I ++V+TAA CF P V + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 L +++ + + Y + D+ L++L N T + LP + T Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRR 193 T C V GWG + G + + + P ++C+ +C G Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGG 180 Query: 194 GGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG--PDFFTRVALFRDWI 239 C GD G PLVC+ G+ S+ G C R P +T+V+ + DWI Sbjct: 181 TDACKGDSGGPLVCKHSGRWQLVGITSWGEG-CARKDQPGVYTKVSEYMDWI 231 >1FUJ-A nrPDB Length = 221 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 99/223 (44%), Positives = 138/223 (61%), Gaps = 7/223 (3%) Query: 27 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG +A+P P++AS+Q N G HFCGG LIH FV+TAA C + + VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++R +E +Q FS++ + N YD + LND++L+QL ANL++SV + LP Q+ V Sbjct: 61 HNVRTQEPT-QQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGT 203 GT+C GWG + ++ + +NVTV CRP+N+CT V R+ GIC GD G Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHNICTFVPRRKAGICFGDSGG 178 Query: 204 PLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 PL+C+G+ G+ SF + C PDFFTRVAL+ DWI L Sbjct: 179 PLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1SGF-G nrPDB Length = 237 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 109/243 (44%), Gaps = 29/243 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG K P+ ++ ++ CGG L+ +V+TAA C+ V LG +L Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGKNNL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQ-----------QNLNDLMLLQLDREANLTSSVTILP 135 + E ++ F ++ G++ NDLMLL+L + A++T +V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPN--------NVC 186 LP + + G+ C +GWGS + + VN+ + P + C +C Sbjct: 117 LPTEE--PKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL- 243 G + C GD G PL+C+G+ G+ S+ PCG P +T++ F WI + Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 244 NNP 246 NP Sbjct: 235 KNP 237 >2TLD-E nrPDB Length = 220 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 67/228 (29%), Positives = 109/228 (47%), Gaps = 18/228 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S V LG ++ Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGEDNI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 E + + S+ Y+ ND+ML++L A+L S V + LP + AG Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCASAG 113 Query: 147 TRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGIC 197 T+C ++GWG+ +S G + + + + C+ N C G+ G C Sbjct: 114 TQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE--GGDSC 171 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G P+VC G G+ S+ G P +T+V + WI + + Sbjct: 172 QGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTIAS 219 >1IAU-A nrPDB Length = 227 Score = 269 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 74/231 (32%), Positives = 111/231 (48%), Gaps = 17/231 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH---FCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A + + CGG LI FV+TAA C+ S V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++ +E + + Y+P+ ND+MLLQL+R+A T +V L LP A V Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTRRG 194 + G C VAGWG G+ S + V +TV + +C + +C G + Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G PLVC +A G+ S+ G P T+V+ F WI + Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSYGRNN-GMPPRACTKVSSFVHWIKKTMKR 226 >4NFE-A nrPDB Length = 237 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 106/239 (44%), Gaps = 28/239 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ ++ + G CGG L+H ++V+TAA C + S V LG ++L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN----SQVWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREANLTSSVTILP 135 E ++ S Y+ + + +DLMLL+L A +T V +L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNVC 186 LP Q GT C +GWGS L R + V++ + D C +C Sbjct: 117 LPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 G+ T C GD G PLVC G+ G+ S+ PC P +T+V +R WI + Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 233 >1NN6-A nrPDB Length = 228 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 71/230 (30%), Positives = 107/230 (46%), Gaps = 16/230 (6%) Query: 26 DIVGGRKARPRQFPFLASI----QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVL 81 +I+GG + +P P++A + N FCGG LI FV+TAA C TV L Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVTL 57 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 GA+++ E ++ I Y+ +D+MLL+L +A+LT +V LP P Q Sbjct: 58 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 117 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN-------NVCTGVLTRRG 194 V G C+VAGWG S + V + + C +C G + Sbjct: 118 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTK 177 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 GD G PL+C G+A G+ S+ + P FTR++ +R WI+ +L Sbjct: 178 SAFKGDSGGPLLCAGVAQGIVSYGRSD-AKPPAVFTRISHYRPWINQILQ 226 >3W94-A nrPDB Length = 235 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 68/234 (29%), Positives = 105/234 (44%), Gaps = 19/234 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGV--STVVLGAY 84 +VGG A +P++ S+ +GRH CG +LI +++TAA C +N + + VLG + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 85 DLRRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 Q Q + + N Y+ + D+ ++ L + N T V + L ++ Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRRG 194 AG RC +AGWG GG L + V + +D+C+ + +C G Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGGV 180 Query: 195 GICNGDGGTPLVC----EGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGV 242 C GD G PL+C GV SF +G CGR P + RV+ F WI Sbjct: 181 DSCQGDSGGPLMCLEDARWTLIGVTSFGVG-CGRPERPGAYARVSAFTSWIAET 233 >1P57-B nrPDB Length = 255 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 65/243 (26%), Positives = 104/243 (42%), Gaps = 25/243 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGR ++P+ S++ G H CGG+L+ +V+TAA CF +N +S + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 87 RRRERQSRQTFSISSMSENGY------DPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + Q + + GY + ++N ND+ L+ L LT + + LP Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + G C V GWG+ + G+ + + V + D C +P C G Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 180 Query: 191 TRRGGICNGDGGTPLVCE--------GLAHGVASFSLGPC-GRGPDFFTRVALFRDWIDG 241 C GD G P VCE G+ S+ G + P +T+V+ FR+WI Sbjct: 181 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQ 240 Query: 242 VLN 244 + Sbjct: 241 AIK 243 >2EEK-A nrPDB Length = 220 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 65/226 (28%), Positives = 100/226 (44%), Gaps = 16/226 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + S+ N G HFCGG+L+ +V++AA C++S V V LG + + Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKS----VLRVRLGEHHI 55 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E + S S + Y ND+ML++L + A L V + LP + A Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADA-- 113 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGICN 198 T C V+GWG+ S + +++ + C + C G L C Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVL 243 GD G P+VC G+ GV S+ G R P + +V + W+ + Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >5MS3-A nrPDB Length = 228 Score = 263 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 66/235 (28%), Positives = 111/235 (47%), Gaps = 21/235 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + +P P+ A++ + CGG L+ +V+TAA C TV LG + L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSL 56 Query: 87 RRRERQSRQTFSISSMSENGYDP---QQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + ++ ++ + S+ Y+ + + +DLMLLQL +A+L S V + L + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--ADHCT 114 Query: 144 EAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRG 194 + G +C V+GWG+ V + P+ +C VC G ++ Sbjct: 115 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SKGA 173 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNNPG 247 C GD G PLVC+G G+ S+ PCGR P +T + + DWI ++ + G Sbjct: 174 DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 228 >1FXY-A nrPDB Length = 228 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 57/228 (25%), Positives = 93/228 (40%), Gaps = 15/228 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGG + + P+ A + N+ FCGG ++ +++TAA C V +G + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR--FKVRVGDRN 58 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + E + N + + D+ +L+L +V LP A Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPT--APPAT 116 Query: 146 GTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGGI 196 GT+C ++GWG+ S G + ++ V + +C N C G L Sbjct: 117 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS 176 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 C GD G P+VC G GV S+ G + P +T+V + WI + Sbjct: 177 CQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >2F83-A nrPDB Length = 625 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 55/232 (23%), Positives = 98/232 (42%), Gaps = 18/232 (7%) Query: 26 DIVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQS-QNPGVSTVVL 81 IVGG + ++P+ ++ RH CGG++I ++++TAA CF ++P + V Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 G + + + + + Y ++ D+ LL+L+ N T S + LP + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTR 192 T C V GWG ++ ++ + + + ++C+ +C G Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 566 Query: 193 RGGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRDWI 239 C GD G PL C+ G+ S+ G R P +T V + DWI Sbjct: 567 GKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >1FDP-A nrPDB Length = 235 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 79/233 (33%), Positives = 110/233 (47%), Gaps = 14/233 (6%) Query: 23 PLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 P I+GGR+A P++AS+Q G H CGG L+ ++V++AA C + G V+LG Sbjct: 4 PRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLG 63 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A+ L + E R + ++ P +DL+LLQL +A L +V LP + Sbjct: 64 AHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRD 123 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN----------VCTGVLTR 192 V GT C VAGWG GR + V + V C +C + Sbjct: 124 VAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ESN 181 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 R C GD G PLVC G+ GV + CG + P +TRVA + WID VL Sbjct: 182 RRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1SPJ-A nrPDB Length = 238 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 106/240 (44%), Gaps = 29/240 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ A++ + CGG L+H ++V+TAA C + LG ++L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDN----YQLWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREA-NLTSSVTIL 134 E ++ S G++ + +DLMLL+L A +T +V ++ Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 135 PLPLQNATVEAGTRCQVAGWGSQR-SGGRLSRFPRFVNVTVTPEDQCRPN--------NV 185 LP + E G+ C +GWGS + V++ + P D+C+ + Sbjct: 117 ELPTEE--PEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFML 174 Query: 186 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 C G L C GD G PL+C+G+ GV S+ PCG P RV + WI+ + Sbjct: 175 CVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 >4DGJ-A nrPDB Length = 235 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 58/235 (24%), Positives = 101/235 (42%), Gaps = 17/235 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN--PGVSTVVLGAY 84 IVGG A+ +P++ + R CG +L+ + ++++AA C +N P T +LG + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 85 DLRRRERQSRQTFSI-SSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 I + Y+ ++ ND+ ++ L+ + N T + + LP +N Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRRG 194 G C +AGWG+ G + + +V + ++C+ N +C G Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGI 180 Query: 195 GICNGDGGTPLVCE----GLAHGVASFSLGPC-GRGPDFFTRVALFRDWIDGVLN 244 C GD G PL+C+ GV SF P + RV+ F +WI L+ Sbjct: 181 DSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQSFLH 235 >3G01-A nrPDB Length = 227 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 78/232 (33%), Positives = 112/232 (48%), Gaps = 18/232 (7%) Query: 27 IVGGRKARPRQFPFLA---SIQNQGR-HFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG + P P++A ++ G+ FCGG L+ +FV+TAA C TV LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A++++ +E + ++ Y+P ND+MLL+L R A T +V L LP +NA Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRR 193 V+ G C VAGWG G + V +TV + C R N +C G + Sbjct: 117 VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIK 176 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 G GD G PLVC+ A G+ S+ G P FTRV F WI + + Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSYGQTD-GSAPQVFTRVLSFVSWIKKTMKH 227 >1NPM-A nrPDB Length = 225 Score = 259 bits (663), Expect = 6e-70, Method: Composition-based stats. Identities = 63/232 (27%), Positives = 110/232 (47%), Gaps = 21/232 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ GR+ P P+ A++ R CGG L+ R+V+TAA C + + +V LG + L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQK----YSVRLGDHSL 56 Query: 87 RRRERQSRQTFSISSMSENGY---DPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + R++ ++ S+ Y +P+ + +D+ML++L ANL V + L N Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLCP 114 Query: 144 EAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRG 194 + G +C ++GWG+ V + +++C VC G + Sbjct: 115 KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SNGA 173 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLN 244 C GD G PLVC+G+ G+ S+ PCG+ P +T++ + WI ++ Sbjct: 174 DTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMD 225 >1EKB-B nrPDB Length = 235 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 17/235 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN--PGVSTVVLGAY 84 IVGG +R +P++ ++ + CG +L+ ++++AA C +N P VLG + Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 85 DLRRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +T I + Y+ ++ ND+ ++ L+ + N T + + LP +N Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRRG 194 G C +AGWG+ G + + +V + ++C+ N VC G Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGGV 180 Query: 195 GICNGDGGTPLVCE----GLAHGVASFSLGPC-GRGPDFFTRVALFRDWIDGVLN 244 C GD G PL+C+ L GV SF P + RV F +WI L+ Sbjct: 181 DSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFLH 235 >3TK9-A nrPDB Length = 226 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 75/231 (32%), Positives = 114/231 (49%), Gaps = 18/231 (7%) Query: 27 IVGGRKARPRQFPFLAS---IQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A+P P++A +Q + R CGG L+ FV+TAA C V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC----QGSSINVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++ +ER + + Y+P+ N++MLLQL+R+A T++V L LP A V Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRRG 194 + G C VAGWG S L+ + V +TV + QC R +C G + Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G PLVC+ +A G+ S+ G P + +V+ F WI + Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYGNKK-GTPPGVYIKVSHFLPWIKRTMKR 225 >3QUM-P nrPDB Length = 237 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 72/239 (30%), Positives = 108/239 (45%), Gaps = 28/239 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG + P+ + ++GR CGG L+H ++V+TAA C +++ S ++LG + L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREANLTSSVTILP 135 E + S YD + +DLMLL+L A LT +V ++ Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNVC 186 LP Q GT C +GWGS L + + V++ V D C +C Sbjct: 117 LPTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 G T C+GD G PLVC G+ G+ S+ PC P +T+V +R WI + Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >1X7A-C nrPDB Length = 235 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 105/233 (45%), Gaps = 21/233 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG A+P QFP+ + + FCGG++I+ ++V+TAA C + TVV G Y+ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCI--EPGVKITVVAGEYNT 58 Query: 87 RRRERQSRQTFSISSMSENGYDP--QQNLNDLMLLQLDREANLTSSVTILPLPLQNAT-- 142 E ++ I ++ + Y+ + +D+ LL+LD L S VT + + + T Sbjct: 59 EETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNI 118 Query: 143 -VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRR 193 ++ G+ V+GWG + GR + +++ V + C N C G Sbjct: 119 FLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGG 177 Query: 194 GGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDG 241 C GD G P V E G+ S+ + +T+V+ + +WI Sbjct: 178 KDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKE 230 >5UGG-A nrPDB Length = 251 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 104/238 (43%), Gaps = 26/238 (10%) Query: 26 DIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCF-QSQNPGVSTVVLGA 83 +VGG A P +P+ S++ + G HFCGG LI +V+TAA C +S P V+LGA Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + E ++ E D+ LL+L A +T V LP N V Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVV 134 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVLTRR 193 T C + GWG + G + + + V C + +C G L Sbjct: 135 ADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 193 Query: 194 GGICNGDGGTPLVC----EGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 C GD G PLVC + + GV S+ LG C R P + RV+ F WI+GV+ N Sbjct: 194 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGVMRN 250 >3BSQ-A nrPDB Length = 227 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 69/229 (30%), Positives = 110/229 (48%), Gaps = 19/229 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G P+ ++ + + CGG L++ R+V+TAA C TV LG+ L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 +R++++ + S GY Q ++NDLML++L+ +A L+S V + LP + G Sbjct: 57 --GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 112 Query: 147 TRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 197 T C V+GWG+ S V+V + C + +C G+ + C Sbjct: 113 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 172 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 NGD G PLVC G G+ S+ PCG+ P +T+V F WI+ + Sbjct: 173 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >4DUR-A nrPDB Length = 791 Score = 256 bits (655), Expect = 5e-69, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 104/238 (43%), Gaps = 26/238 (10%) Query: 26 DIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCF-QSQNPGVSTVVLGA 83 +VGG A P +P+ S++ + G HFCGG LI +V+TAA C +S P V+LGA Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + E ++ E D+ LL+L A +T V LP N V Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVV 674 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVLTRR 193 T C + GWG + G + + + V C + +C G L Sbjct: 675 ADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 733 Query: 194 GGICNGDGGTPLVC----EGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 C GD G PLVC + + GV S+ LG C R P + RV+ F WI+GV+ N Sbjct: 734 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGVMRN 790 >3LC3-A nrPDB Length = 235 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 21/233 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 +VGG A+P QFP+ + + FCGG++++ ++++TAA C + TVV G +++ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV--ETGVKITVVAGEHNI 58 Query: 87 RRRERQSRQTFSISSMSENGYDP--QQNLNDLMLLQLDREANLTSSVTILPLPLQNAT-- 142 E ++ I + + Y+ + +D+ LL+LD L S VT + + + T Sbjct: 59 EETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNI 118 Query: 143 -VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRR 193 ++ G+ V+GWG GR + +++ V + C N C G Sbjct: 119 FLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGG 177 Query: 194 GGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDG 241 C GD G P V E G+ S+ + +T+V+ + +WI Sbjct: 178 RDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 230 >3RP2-A nrPDB Length = 224 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 77/229 (33%), Positives = 116/229 (50%), Gaps = 16/229 (6%) Query: 27 IVGGRKARPRQFPFLASI----QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG ++ P P++A + + R CGG LI +FV+TAA C TV+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A+D+R+RE ++ + Y+ NL+D+MLL+L+++ LT +V ++PLP + Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------RPNNVCTGVLTRRGG 195 + G C AGWG S R V + + E C VC G T Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 GD G PL+C G+AHG+ S+ P + P FTRV+ + WI+ V+N Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSYG-HPDAKPPAIFTRVSTYVPWINAVIN 224 >6QHB-A nrPDB Length = 223 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 17/229 (7%) Query: 28 VGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLR 87 V G P+ A++ G CGG LIH +V+TAA C V LG ++L Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHNLG 57 Query: 88 RRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGT 147 ++E Q+ + ++ YD + D+MLL+L R A L+ + LPL+ T Sbjct: 58 QQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTT 115 Query: 148 RCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGGICNG 199 C + GWG G + + + ++C N +C G C G Sbjct: 116 SCHILGWGKTADGD-FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQG 174 Query: 200 DGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLNNP 246 D G PLVC G+ S+ PCG P +T V + +WI + Sbjct: 175 DSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >5FCR-A nrPDB Length = 234 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 76/231 (32%), Positives = 111/231 (48%), Gaps = 15/231 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGAYD 85 I+GG++A P++AS+Q G H CGG L+ ++V++AA C S V+LGA+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L E R S + G P +DL+L +L + A+L V LPL ++ VE Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP----------NNVCTGVLTRRGG 195 GT C VAGWG GR + V++ C N +C + R Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESNRRD 178 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPC--GRGPDFFTRVALFRDWIDGVLN 244 C GD G+PLVC GV ++ C G+ P +TRV+ +R WI+ + N Sbjct: 179 TCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITN 229 >3E0N-B nrPDB Length = 271 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 62/246 (25%), Positives = 99/246 (40%), Gaps = 24/246 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG-VSTVVLGAYD 85 I GG A Q+P+ SI +G H CGG+L+ ++V++AA CF S++ V LGA+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L ++ + + Y + + D+ LLQL R + + + LP A+ Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 146 GTRCQVAGWGSQRSGGRL--SRFPRFVNVTVTPEDQC----------------RPNNVCT 187 G C V GWG L + + + V + + C + + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 188 GVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGV 242 G + C GD G PL C G+ S+ R P +T + + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSK 240 Query: 243 LNNPGP 248 + P Sbjct: 241 VTELQP 246 >1AO5-A nrPDB Length = 237 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 63/239 (26%), Positives = 103/239 (43%), Gaps = 28/239 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 +VGG P+ ++ Q H CGG L+ +V+TAA C+ Q V LG L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQ-----------QNLNDLMLLQLDREANLTSSVTILP 135 + E ++ S G++ +DLMLL+L + A++T V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 136 LPLQNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCRP--------NNVC 186 LP + + G++C +GWGS + + + V +T+ P + C +C Sbjct: 117 LPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 243 G + C D G PL+C+G+ G S+ PCG+ P +T + F WI + Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 233 >1KIG-H nrPDB Length = 241 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 60/238 (25%), Positives = 97/238 (40%), Gaps = 21/238 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGGR + P+ A + N+ FCGG +++ +V+TAA C TV +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKR--FTVRVGDRN 58 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN---AT 142 + E ++ + + + D+ +L+L +V LP ++ AT Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRG 194 + V+G+G GRLS + + V C+ PN C G T+ Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPE 178 Query: 195 GICNGDGGTPLVCE----GLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGVLNNP 246 C GD G P V G+ S+ G C R +T+V+ F WID ++ Sbjct: 179 DACQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKFGVYTKVSNFLKWIDKIMKAR 235 >1TON-A nrPDB Length = 235 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 107/241 (44%), Gaps = 30/241 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG K P+ ++ N+ + CGG LI +V+TAA C+ + V+LG +L Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCYSNN----YQVLLGRNNL 54 Query: 87 RRRERQSRQTFSISSMSENGYDP-----------QQNLNDLMLLQLDREANLTSSVTILP 135 + E +++ S Y P + NDLMLL L A++T V ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPN--------NVC 186 LP + + G+ C +GWGS +S + VN+ + ++C +C Sbjct: 115 LPTKE--PKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 G + C GD G PL+C+G+ G+ S PC + P + ++ F WI V+ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 245 N 245 Sbjct: 233 E 233 >3DFJ-A nrPDB Length = 263 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 62/239 (25%), Positives = 98/239 (41%), Gaps = 24/239 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG-VSTVVLGAYD 85 I GG A Q+P+ SI +G H CGG+L+ ++V++AA CF S++ V LGA+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L ++ + + Y + + D+ LLQL R + + + LP NA+ Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 146 GTRCQVAGWGSQRSGGRL--SRFPRFVNVTVTPEDQC----------------RPNNVCT 187 G C V GWG L + + + V + + C + + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 188 GVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDG 241 G + C GD G PL C G+ S+ R P +T + + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQS 239 >6AOD-C nrPDB Length = 245 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLG 82 IVGG + ++P+ ++ RH CGG++I ++++TAA CF ++P + V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 + + + + Y ++ D+ LL+L+ T S + LP + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTRR 193 T C V GWG ++ ++ + + + ++C+ +C G Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 194 GGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRDWI 239 C GD G PL C+ G+ S+ G R P +T V + DWI Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >1BRU-P nrPDB Length = 241 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 73/243 (30%), Positives = 102/243 (41%), Gaps = 27/243 (11%) Query: 27 IVGGRKARPRQFPFLASIQN----QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG ARP +P+ S+Q Q RH CGG L+ +V+TAA C S VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSR--TYRVVLG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQ--QNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + L E S + ++ N ND+ LL+L +LT + + LP Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + C V GWG ++ G + + V C + N +C G Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG- 177 Query: 191 TRRGGICNGDGGTPLVC-----EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDWIDGV 242 CNGD G PL C + HG+ SF C P FTRV+ + DWI+ V Sbjct: 178 DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSV 237 Query: 243 LNN 245 + N Sbjct: 238 IAN 240 >5ZFH-A nrPDB Length = 224 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 60/229 (26%), Positives = 104/229 (45%), Gaps = 19/229 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G K + P+ ++ + CGG L+ +V+TAA C G V LG+ + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHC----KMGQYQVQLGSDKI 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 ++ +++ + S GY + ++ND+ML++LD ++S V + LP G Sbjct: 57 --GDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLP--EHCEPPG 112 Query: 147 TRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGGIC 197 T C V+GWG+ S +V + +C+ +C G+ + C Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTC 172 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 NGD G PLVC G+ S+ PCG+ P +T+V ++ W+ + Sbjct: 173 NGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >1ORF-A nrPDB Length = 234 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 79/234 (33%), Positives = 106/234 (45%), Gaps = 19/234 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P++ + + C GALI +V+TAA C S V+LGA+ + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 57 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E + YDP DL LLQL +A + VTIL LP + V+ G Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP------------NNVCTGVLTRRG 194 T CQVAGWG + S R V +T+ C N VC G L Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 177 Query: 195 GICNGDGGTPLVCEGLAHGVASFS-LGPCG--RGPDFFTRVA-LFRDWIDGVLN 244 CNGD G+PL+CEG+ GV SF CG RGP + ++ +WI + Sbjct: 178 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >3P8G-A nrPDB Length = 241 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 104/237 (43%), Gaps = 22/237 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGR-HFCGGALIHARFVMTAASC------FQSQNPGVSTV 79 +VGG A ++P+ S+ G+ H CG +LI ++++AA C F+ +P T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 80 VLGAYDLRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL 138 LG +D +R Q + + ++ D+ LL+L++ A +S V + LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 139 QNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVL 190 + AG V GWG + GG + + + V + C P +C G L Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGFL 180 Query: 191 TRRGGICNGDGGTPLV---CEG--LAHGVASFSLGPCGR-GPDFFTRVALFRDWIDG 241 + C GD G PL +G GV S+ G R P +TR+ LFRDWI Sbjct: 181 SGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 237 >4H4F-A nrPDB Length = 249 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 26/241 (10%) Query: 27 IVGGRKARPRQFPFLASIQN----QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG ARP +P+ S+Q RH CGG LI + FV+TAA C N V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--SNTRTYRVAVG 58 Query: 83 AYDLRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 +L + + + ++ ++ ND+ L++L L+ ++ + LP +++ Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVLT 191 + C V GWG + G ++ + V C + VC G Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-D 177 Query: 192 RRGGICNGDGGTPLVCE-----GLAHGVASFSL-GPCG--RGPDFFTRVALFRDWIDGVL 243 CNGD G PL C+ G+ SF C + P +TRV+ + DWI+ + Sbjct: 178 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 237 Query: 244 N 244 Sbjct: 238 Q 238 >2CGA-A nrPDB Length = 245 Score = 247 bits (631), Expect = 3e-66, Method: Composition-based stats. Identities = 64/237 (27%), Positives = 101/237 (42%), Gaps = 20/237 (8%) Query: 22 SPLLDIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVSTVV 80 S L IV G +A P +P+ S+Q++ G HFCGG+LI+ +V+TAA C VV Sbjct: 11 SGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVV 67 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 G +D + ++ + Y+ ND+ LL+L A+ + +V+ + LP + Sbjct: 68 AGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSAS 127 Query: 141 ATVEAGTRCQVAGWGSQR-SGGRLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLT 191 AGT C GWG R + + ++ + C+ +C G Sbjct: 128 DDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--A 185 Query: 192 RRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 C GD G PLVC+ G+ S+ C P + RV +W+ L Sbjct: 186 SGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 242 >2RDL-A nrPDB Length = 226 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 71/230 (30%), Positives = 110/230 (47%), Gaps = 16/230 (6%) Query: 27 IVGGRKARPRQFPFLASI--QNQGRHF--CGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+GG + RP P++A + H C G LI FVMTAA C TV+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC----AGRSITVLLG 56 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 A++ + +E ++ YD + LND+MLL+L +ANLT V LP+ ++ + Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNS 116 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------PNNVCTGVLTRRGG 195 + G C+ GWG S + V + + C+ +C G + Sbjct: 117 IPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRN 176 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 + GD G PL+C G+A G+AS+ L + P FTR++ +R WI+ +L Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVLRN-AKPPSVFTRISHYRPWINKILRE 225 >1KYN-A nrPDB Length = 235 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 78/231 (33%), Positives = 114/231 (49%), Gaps = 17/231 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GGR++RP P++A +Q Q G+ CGG L+ FV+TAA C+ S V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN----INVTLGA 56 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 ++++RRE + + ++ Y+ + ND+MLLQL R +V + LP + Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGG 195 GT C VAGWG S R + R V + V + QC +C G R Sbjct: 117 RPGTLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKA 175 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNP 246 GD G PL+C +AHG+ S+ G P+ FTRV+ F WI + + Sbjct: 176 AFKGDSGGPLLCNNVAHGIVSYGKSS-GVPPEVFTRVSSFLPWIRTTMRSF 225 >1C5M-D nrPDB Length = 255 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 21/239 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGG++ + + P+ A + N+ FCGG ++ +++TAA C V +G + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR--FKVRVGDRN 58 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLP---LQNAT 142 + E + N + + D+ +L+L +V LP +T Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRG 194 + V+G+G GR S + + V + C+ N C G T++ Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 178 Query: 195 GICNGDGGTPLVCE----GLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGVLNNPG 247 C GD G P V G+ S+ G C R +T+V F WID + G Sbjct: 179 DACQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKYGIYTKVTAFLKWIDRSMKTRG 236 >2PSX-A nrPDB Length = 227 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 65/231 (28%), Positives = 103/231 (44%), Gaps = 20/231 (8%) Query: 27 IVGGRKARPRQFPFLASIQ-NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 I+ G P+ A++ + +CG L+H ++++TAA C V V LG Y Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYS 56 Query: 86 LRRRERQSRQTFS-ISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 L +Q F + S+ GY + NDLML++L+R T V + + + Sbjct: 57 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVS--SHCPS 114 Query: 145 AGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGG 195 AGT+C V+GWG+ +S + + +N++V + +C C G R Sbjct: 115 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGR-D 173 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 C GD G P+VC G G+ S+ PC R P +T + F WI + Sbjct: 174 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >1MZD-A nrPDB Length = 240 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 75/238 (31%), Positives = 110/238 (46%), Gaps = 17/238 (7%) Query: 25 LDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGA 83 ++I+GG++ P PF+ASIQ G H CGG LI ++V+TAA C G S TVVLGA Sbjct: 1 MEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGA 60 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + L + E + + + ND+ML++L A L V +L + ++ Sbjct: 61 HSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKTSL 119 Query: 144 EAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCR------------PNNVCTGVL 190 +GT+C+V GWG+ R S R V VTV C + VC G Sbjct: 120 RSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDA 179 Query: 191 TRRGGICNGDGGTPLVCEGLAHGVASFSLGP-CGRGPDFFTRVA-LFRDWIDGVLNNP 246 + C GD G PL+C+G+ H + S P +T + ++ WI L P Sbjct: 180 KGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPP 237 >1PPF-E nrPDB Length = 218 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 100/220 (45%), Positives = 134/220 (60%), Gaps = 4/220 (1%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGGR+ARP +PF+ S+Q +G HFCG LI FVM+AA C + N VVLGA++L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 RRE RQ F++ + ENGYDP LND+++LQL+ A + ++V + LP Q + G Sbjct: 61 SRREPT-RQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 119 Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 206 +C GWG ++ + +NVTV CR +NVCT V R+ G+C GD G+PLV Sbjct: 120 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVRGRQAGVCFGDSGSPLV 178 Query: 207 CEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 C GL HG+ASF G C G PD F VA F +WID ++ Sbjct: 179 CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >4Q7Y-A nrPDB Length = 250 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 87/238 (36%), Positives = 123/238 (51%), Gaps = 14/238 (5%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P P++AS++ G+H CGG L+ AR+V++AA CF ++ VVLGA+ L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE-A 145 E + + + Y P + ND+ LL+L+ A L +V +L LP + A A Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN--------NVCT-GVLTRRGGI 196 GTRC+VAGWG L V V D C + +CT + R G Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 180 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLN--NPGPGP 250 C+ D G PLVC AHG+ SFS CG + PD +T+V+ F WI V+ +P PGP Sbjct: 181 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGP 238 >2F91-A nrPDB Length = 237 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 92/236 (38%), Gaps = 25/236 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQ----GRHFCGGALIHARFVMTAASCFQS---QNPGVSTV 79 IVGG A +FP+ S Q HFCG ++ + + +TA C +NP + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 80 VLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQ 139 V G D+ E + + +D ND+ LL+L +V + LP Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVL 190 T A V GWG+ GG + V V + ++ CR + +C GV Sbjct: 121 GHT--ATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 191 TRRGGICNGDGGTPLVCEGL----AHGVASFSLGPCGRG--PDFFTRVALFRDWID 240 C GD G PL G+ S+ G C R P +T V+ DWI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYG-CARPGYPGVYTEVSYHVDWIK 233 >1Q3X-A nrPDB Length = 328 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 111/270 (41%), Gaps = 33/270 (12%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61 L V + GL A + G I GG+KA+P FP+ I G GAL++ + Sbjct: 67 KSLPVCEPVCGLSARTTGG-----RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 119 Query: 62 VMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGY-DPQQNLNDLMLLQ 120 V+TAA Q S + + L+R Q +S + GY ND+ L++ Sbjct: 120 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 179 Query: 121 LDREANLTSSVTILPLPLQNA--TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED 178 L+ + + S++T + LP + A + +GWG + G L+R +V++ + Sbjct: 180 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQ 238 Query: 179 QC--------------RPNNVCTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFS 218 +C N +C G+ + C GD G LV G+ S+ Sbjct: 239 KCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWG 298 Query: 219 LGPCGRGP--DFFTRVALFRDWIDGVLNNP 246 CG +T+V + WI+ ++++ Sbjct: 299 SMNCGEAGQYGVYTKVINYIPWIENIISDF 328 >4Z6A-H nrPDB Length = 249 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 61/241 (25%), Positives = 94/241 (39%), Gaps = 18/241 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG+ + P+ + G CGG LI+ +V++AA CF +N VLG +D Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL---QNAT 142 L + + + + Y P +D+ LL+L + LT V L LP T Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 143 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN--------NVCTGVLTRRG 194 + V+GWG G + +NV C + C G Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSK 180 Query: 195 GICNGDGGTPLVCE----GLAHGVASFSLGPCGRGP-DFFTRVALFRDWIDGVLNN-PGP 248 C GD G P G+ S+ G G +TRV+ + +W+ ++ + P P Sbjct: 181 DSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRP 240 Query: 249 G 249 G Sbjct: 241 G 241 >1GVZ-A nrPDB Length = 237 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 28/241 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG + P+ ++ +QG CGG L+H ++V+TAA C + LG ++L Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSD----DYQIWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREANLTSSVTILP 135 + E ++ S + +D +DLMLL+L + A +T +V IL Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 136 LPLQNATVEAGTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCRPNN--------VC 186 LP Q + G+ C +GWG + R S + V + + ++C +C Sbjct: 117 LPTQE--PKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLC 174 Query: 187 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLN 244 G IC GD G L+C+G+ G+ S+ C D FT+V + WI + Sbjct: 175 ATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIE 234 Query: 245 N 245 Sbjct: 235 K 235 >2AIQ-A nrPDB Length = 231 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 60/229 (26%), Positives = 102/229 (44%), Gaps = 18/229 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + + FLA + G CGG LI+ +V+TA C + G + LG ++L Sbjct: 1 VIGGDECNINEHRFLALVYANGS-LCGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 87 RRRERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + + + F N + D+ML++L+R ++ + L LP + Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLP--SNPPSV 113 Query: 146 GTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCRP-------NNVCTGVLTRRGGIC 197 G+ C++ GWG+ L P N+ + C+ +C G+L C Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGKDTC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLN 244 GD G PL+C G G+ S PC R P +T+V + DWI +++ Sbjct: 174 KGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIIS 222 >1SGF-A nrPDB Length = 240 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 56/236 (23%), Positives = 97/236 (41%), Gaps = 29/236 (12%) Query: 32 KARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRER 91 P+ ++ ++ CGG L+ +V+TAA C+ + V LG + E Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDK----YQVWLGKNNFLEDEP 64 Query: 92 QSRQTFSISSMSENGYD-----------PQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 + ++ ++ NDLMLL+L + A++T V + LP + Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEE 124 Query: 141 ATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPN--------NVCTGVLT 191 + G+ C +GWGS + + VN+ + P + C +C G + Sbjct: 125 --PKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMD 182 Query: 192 RRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNN 245 C D G PL+C+G+ G+ S+ PCG P +T++ F WI + N Sbjct: 183 GGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMAN 238 >3K65-B nrPDB Length = 308 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 104/260 (40%), Gaps = 39/260 (15%) Query: 26 DIVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVS 77 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 49 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 108 Query: 78 TVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILP 135 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + + Sbjct: 109 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 168 Query: 136 LPLQNA---TVEAGTRCQVAGWGSQRS------GGRLSRFPRFVNVTVTPEDQCR----- 181 LP + ++AG + +V GWG+ + G + VN+ + C+ Sbjct: 169 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 228 Query: 182 ---PNNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--D 227 N C G +RG C GD G P V + G+ S+ G C R Sbjct: 229 RITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 287 Query: 228 FFTRVALFRDWIDGVLNNPG 247 F+T V + WI V++ G Sbjct: 288 FYTHVFRLKKWIQKVIDQFG 307 >1BDA-A nrPDB Length = 265 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 71/262 (27%), Positives = 108/262 (41%), Gaps = 35/262 (13%) Query: 18 RAGSSPLLDIVGGRKARPRQFPFLASIQNQ------GRHFCGGALIHARFVMTAASCFQS 71 R S P I GG A P+ A+I + R CGG LI + ++++AA CFQ Sbjct: 5 RQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQE 64 Query: 72 Q-NPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQL----DREAN 126 + P TV+LG + ++ + +D ND+ LLQL R A Sbjct: 65 RFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQ 124 Query: 127 LTSSVTILPLPLQNATVEAGTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCRP--- 182 +S V + LP + + T C+++G+G + S + +V + P +C Sbjct: 125 ESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHL 184 Query: 183 -------NNVCTGVLTRRG------GICNGDGGTPLVC----EGLAHGVASFSLGPCGRG 225 N +C G G C GD G PLVC G+ S+ LG CG+ Sbjct: 185 LNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLG-CGQK 243 Query: 226 --PDFFTRVALFRDWIDGVLNN 245 P +T+V + DWI + Sbjct: 244 DVPGVYTKVTNYLDWIRDNMRP 265 >3NXP-A nrPDB Length = 424 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 104/260 (40%), Gaps = 39/260 (15%) Query: 26 DIVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVS 77 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 165 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 224 Query: 78 TVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILP 135 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + + Sbjct: 225 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 284 Query: 136 LPLQNA---TVEAGTRCQVAGWGSQRS------GGRLSRFPRFVNVTVTPEDQCR----- 181 LP + ++AG + +V GWG+ + G + VN+ + C+ Sbjct: 285 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 344 Query: 182 ---PNNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--D 227 N C G +RG C GD G P V + G+ S+ G C R Sbjct: 345 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 403 Query: 228 FFTRVALFRDWIDGVLNNPG 247 F+T V + WI V++ G Sbjct: 404 FYTHVFRLKKWIQKVIDQFG 423 >1PYT-D nrPDB Length = 251 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 25/243 (10%) Query: 21 SSPLLDIVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGV 76 + +VGG A P +P+ S+Q N RH CGG LI V+TAA C N Sbjct: 8 PNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI--SNTLT 65 Query: 77 STVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREANLTSSVTILP 135 V LG +L + + ++ ++ ND+ L++L L ++ + Sbjct: 66 YRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVAC 125 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNV 185 LP + + + C V GWG + G ++ + V C + V Sbjct: 126 LPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMV 185 Query: 186 CTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDW 238 C G CNGD G PL C + G+ SF G C + P FTRV+ + DW Sbjct: 186 CAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDW 244 Query: 239 IDG 241 I+ Sbjct: 245 INQ 247 >1MKW-K nrPDB Length = 308 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 64/260 (24%), Positives = 105/260 (40%), Gaps = 39/260 (15%) Query: 26 DIVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVS 77 IV G+ A P+ + + CG +LI R+V+TAA C ++ Sbjct: 49 RIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 78 TVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILP 135 V +G + R ER+ + + + Y+ ++NL+ D+ LL+L R L+ + + Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 136 LPLQNA---TVEAGTRCQVAGWGSQRSGGR------LSRFPRFVNVTVTPEDQCRP---- 182 LP + + AG + +V GWG++R + VN+ + C+ Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 228 Query: 183 ----NNVCTGVLTR---RGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--D 227 N C G RG C GD G P V + G+ S+ G C R Sbjct: 229 RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYG 287 Query: 228 FFTRVALFRDWIDGVLNNPG 247 F+T V + WI V++ G Sbjct: 288 FYTHVFRLKKWIQKVIDRLG 307 >1ZJK-A nrPDB Length = 403 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 111/270 (41%), Gaps = 33/270 (12%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61 L V + GL A + G I GG+KA+P FP+ I G GAL++ + Sbjct: 142 KSLPVCEPVCGLSARTTGGQ-----IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 194 Query: 62 VMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGY-DPQQNLNDLMLLQ 120 V+TAA Q S + + L+R Q +S + GY ND+ L++ Sbjct: 195 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 254 Query: 121 LDREANLTSSVTILPLPLQNA--TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED 178 L+ + + S++T + LP + A + +GWG + G L+R +V++ + Sbjct: 255 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQ 313 Query: 179 QC--------------RPNNVCTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFS 218 +C N +C G+ + C GD G LV G+ S+ Sbjct: 314 KCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWG 373 Query: 219 LGPCGRGP--DFFTRVALFRDWIDGVLNNP 246 CG +T+V + WI+ ++++ Sbjct: 374 SMNCGEAGQYGVYTKVINYIPWIENIISDF 403 >4NZQ-A nrPDB Length = 557 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 104/260 (40%), Gaps = 39/260 (15%) Query: 26 DIVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVS 77 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 298 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 357 Query: 78 TVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILP 135 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + + Sbjct: 358 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 417 Query: 136 LPLQNA---TVEAGTRCQVAGWGSQRS------GGRLSRFPRFVNVTVTPEDQCR----- 181 LP + ++AG + +V GWG+ + G + VN+ + C+ Sbjct: 418 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 477 Query: 182 ---PNNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--D 227 N C G +RG C GD G P V + G+ S+ G C R Sbjct: 478 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 536 Query: 228 FFTRVALFRDWIDGVLNNPG 247 F+T V + WI V++ G Sbjct: 537 FYTHVFRLKKWIQKVIDQFG 556 >4GSO-A nrPDB Length = 232 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 58/229 (25%), Positives = 98/229 (42%), Gaps = 19/229 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + + PFLA + + G +FCG LI+ +V+TAA C + + LG + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHC----DSTNFQMQLGVHSK 55 Query: 87 RRRERQSRQTFSISSMSENGYD-PQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + + + D+ML++LD+ + + + L LP + Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLP--SNPPSV 113 Query: 146 GTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGGI 196 G+ C++ GWGS P N+ + + C+ +C GVL Sbjct: 114 GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDT 173 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+ S+ CG+ P +T V + DWI + Sbjct: 174 CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >2BDH-A nrPDB Length = 223 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 69/229 (30%), Positives = 111/229 (48%), Gaps = 18/229 (7%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+ G P P+ A++ + FC G L+H ++V++AA CFQ+ T+ LG + L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHSL 56 Query: 87 R-RRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 +E S+ + S+ Y+ NDLML++LD + + ++ + + + A Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPTA 114 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 197 G C V+GWG GR+ + VNV+V E+ C P+ C G + C Sbjct: 115 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSC 173 Query: 198 NGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLN 244 NGD G PL+C G G+ SF PCG+ P +T + F +WI+ + Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >4MPW-A nrPDB Length = 245 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 69/243 (28%), Positives = 103/243 (42%), Gaps = 34/243 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQG---RHFCGGALIHARFVMTAASCF--QSQNPGVSTVVL 81 IVGG++A ++P+ S++ G HFCGG+LIH ++V+TAA C ++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 L ++ + + + Q D+ LL+L+ ++S V + LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSR--FPRFVNVTVTPEDQC-----------------RP 182 T G C V GWG + RL + V V + C R Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCG-RGPDFFTRVALFRD 237 + +C G R C GD G PLVC+ L GV S+ G P +TRV + D Sbjct: 178 DMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 235 Query: 238 WID 240 WI Sbjct: 236 WIH 238 >2OCV-B nrPDB Length = 259 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 39/259 (15%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 79 VVLGAYDLRRRERQSRQTFSISSMS-ENGYDPQQNLN-DLMLLQLDREANLTSSVTILPL 136 V +G + R ER + + + Y+ ++NL+ D+ LL+L + + + + L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 137 PLQ---NATVEAGTRCQVAGWGSQRSGGR------LSRFPRFVNVTVTPEDQCRP----- 182 P + + + AG + +V GWG+ R + VN+ + C+ Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 183 ---NNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--DF 228 N C G T+RG C GD G P V + G+ S+ G C R F Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRKGKYGF 239 Query: 229 FTRVALFRDWIDGVLNNPG 247 +T V + WI V++ G Sbjct: 240 YTHVFRLKAWIQKVIDQFG 258 >3F6U-H nrPDB Length = 240 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 100/242 (41%), Gaps = 27/242 (11%) Query: 28 VGGRKARPRQFPFLASIQNQGRHF-CGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 + G+ R P+ + + + CG LIH +V+TAA C + V LG YDL Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLL--VRLGEYDL 59 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN----AT 142 RR E+ Y ND+ LL L + A L+ ++ + LP Sbjct: 60 RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAEREL 119 Query: 143 VEAGTRCQVAGWGSQRSGGRLSR-----FPRFVNVTVTPEDQC--------RPNNVCTGV 189 +AG V GWG S + ++ F+ + V P ++C N +C G+ Sbjct: 120 NQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGI 179 Query: 190 LTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL 243 L R C GD G P+V G+ S+ G CG +T+V+ + DWI G + Sbjct: 180 LGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEG-CGLLHNYGVYTKVSRYLDWIHGHI 238 Query: 244 NN 245 + Sbjct: 239 RD 240 >2V35-A nrPDB Length = 240 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 67/242 (27%), Positives = 104/242 (42%), Gaps = 26/242 (10%) Query: 27 IVGGRKARPRQFPFLASIQN----QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGG +A+ +P S+Q H CGG LI +VMTAA C + VV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDREL--TFRVVVG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQN--LNDLMLLQLDREANLTSSVTILPLPLQN 140 ++L + + + + ++ D+ LL+L + L S V + LP Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAG 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + + C + GWG R+ G+L++ + + C + + VC G Sbjct: 119 TILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGD 178 Query: 191 TRRGGICNGDGGTPLVC----EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDWIDGVL 243 R G C GD G PL C + HGV SF C R P FTRV+ + WI+ V+ Sbjct: 179 GVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 Query: 244 NN 245 + Sbjct: 238 AS 239 >1A5I-A nrPDB Length = 265 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 73/261 (27%), Positives = 106/261 (40%), Gaps = 35/261 (13%) Query: 18 RAGSSPLLDIVGGRKARPRQFPFLASIQNQGR------HFCGGALIHARFVMTAASCFQ- 70 R P L GG P+ A+I Q R CGG LI + +V+TAA CFQ Sbjct: 5 RKYKEPQLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQE 64 Query: 71 SQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD----REAN 126 S P VVLG + + + + +D ND+ LLQL + A Sbjct: 65 SYLPDQLKVVLGRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQ 124 Query: 127 LTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQCRP--- 182 + SV + LP N + T C+++G+G +S S + +V + P +C P Sbjct: 125 ESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFL 184 Query: 183 -------NNVCTGVLTRRG------GICNGDGGTPLVCEGLAH----GVASFSLGPCGRG 225 N +C G C GD G PLVC H G+ S+ +G CG Sbjct: 185 FNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVG-CGEK 243 Query: 226 --PDFFTRVALFRDWIDGVLN 244 P +T+V + WI ++ Sbjct: 244 DVPGVYTKVTNYLGWIRDNMH 264 >1YC0-A nrPDB Length = 283 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 80/260 (30%), Positives = 116/260 (44%), Gaps = 27/260 (10%) Query: 11 AGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQ 70 G R P I+GG + P P+LA+I G FC G+L+H +V++AA CF Sbjct: 22 CGRRHKKRTFLRP--RIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFS 78 Query: 71 SQNPGVS-TVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQ-NLNDLMLLQL----DRE 124 P S +VVLG + R ++ + Y + +DL+L++L DR Sbjct: 79 HSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRC 138 Query: 125 ANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSG-GRLSRFPRFVNVTVTPEDQC--- 180 A + V + LP +T AG +CQ+AGWG S R V + + +C Sbjct: 139 ATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSP 198 Query: 181 -------RPNNVCTGVLTRRGGICNGDGGTPLVCEG----LAHGVASFSLGPCGR--GPD 227 PN +C G + C GD G PL CE +G+ S+ G CGR P Sbjct: 199 EVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPG 257 Query: 228 FFTRVALFRDWIDGVLNNPG 247 +TRVA + DWI+ + P Sbjct: 258 VYTRVANYVDWINDRIRPPR 277 >2OQ5-A nrPDB Length = 232 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 23/233 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG + ++P+ AS+Q G H CG LI+A ++++AA CF + +NP T G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV-- 58 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + + Y + D+ L +L T++V + LP + + Sbjct: 59 --TIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQP 116 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----------PNNVCTGVLTRRGG 195 G V G+G+ ++ G R VT+ C P +C G L + Sbjct: 117 GDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTD 176 Query: 196 ICNGDGGTPLVCE-----GLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDG 241 C GD G PLV G+ S+ C + P +TRV RDWI Sbjct: 177 ACQGDSGGPLVSSDARDIWYLAGIVSWGD-ECAKPNKPGVYTRVTALRDWITS 228 >1ETT-H nrPDB Length = 259 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 105/259 (40%), Gaps = 39/259 (15%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G+ A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 79 VVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILPL 136 V +G + R ER+ + + + Y+ ++NL+ D+ LL+L R L+ + + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 137 PLQNA---TVEAGTRCQVAGWGSQRSGGR------LSRFPRFVNVTVTPEDQCRP----- 182 P + + AG + +V GWG++R + VN+ + C+ Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 183 ---NNVCTGVLTR---RGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--DF 228 N C G RG C GD G P V + G+ S+ G C R F Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYGF 239 Query: 229 FTRVALFRDWIDGVLNNPG 247 +T V + WI V++ G Sbjct: 240 YTHVFRLKKWIQKVIDRLG 258 >2ZKS-A nrPDB Length = 240 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 82/234 (35%), Positives = 112/234 (47%), Gaps = 19/234 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GGR+ P P++AS+Q G H CGG L+H ++V+TAA C +Q +VLG + L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL-AQRMAQLRLVLGLHTL 59 Query: 87 RRRERQSRQTFSISSMSENGYDP-QQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + +++ Y P NDL LLQLD + + ++ L LP + V A Sbjct: 60 ---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAA 116 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----------PNNVCTGVLTRRGG 195 GTRC +AGWG GGRLSR R +++ V C P+ VC ++ Sbjct: 117 GTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQA 176 Query: 196 ICNGDGGTPLVCEG--LAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 C GD G PLVC + GV SFS C P T VA + WI V Sbjct: 177 PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGR 230 >1ELT-A nrPDB Length = 236 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 76/240 (31%), Positives = 112/240 (46%), Gaps = 27/240 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQG----RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 +VGGR A+P +P+ S+Q + H CGG+LI +VMTAA C S VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSAR--TWRVVLG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQ--NLNDLMLLQLDREANLTSSVTILPLPLQN 140 ++L E + + S +G++ D+ LL+L+ +A+L S+V + LP N Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + C + GWG +GG LS + + C + VC G Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGG 178 Query: 191 TRRGGICNGDGGTPLVCE----GLAHGVASF-SLGPC--GRGPDFFTRVALFRDWIDGVL 243 G CNGD G PL C+ HGV SF S C + P FTRV+ + W++G++ Sbjct: 179 ANSG--CNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >4E7N-A nrPDB Length = 238 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 23/234 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGR--HFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 I+GG + + FL ++ FCGG LI+ +V+TAA C + + LG + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC----DRKNFRIKLGMH 56 Query: 85 DLRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 + + + + D+ML++LD +S I P L ++ Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVK--NSKHIAPFSLPSSPP 114 Query: 144 EAGTRCQVAGWGSQRSG-GRLSRFPRFVNVTVTPEDQCR-----------PNNVCTGVLT 191 G+ C++ GWG G P VN+ + + CR +C G+L Sbjct: 115 SVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILE 174 Query: 192 RRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+AS+ PC + P +T+V DWI+ ++ Sbjct: 175 GGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >1LTO-A nrPDB Length = 245 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 34/243 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGR---HFCGGALIHARFVMTAASCF--QSQNPGVSTVVL 81 IVGG++A ++P+ S++ + R HFCGG+LIH ++V+TAA C ++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 L ++ + + + Q D+ LL+L+ N++S V + LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSR--FPRFVNVTVTPEDQC-----------------RP 182 T G C V GWG + L + V V + C R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCG-RGPDFFTRVALFRD 237 + +C G C GD G PLVC+ L GV S+ G P +TRV + D Sbjct: 178 DMLCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLD 235 Query: 238 WID 240 WI Sbjct: 236 WIH 238 >1VR1-H nrPDB Length = 261 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 60/262 (22%), Positives = 103/262 (39%), Gaps = 43/262 (16%) Query: 27 IVGGRKARPRQFPFLASIQNQ------GRHFCGGALIHARFVMTAASCF------QSQNP 74 IV G A P+ + + R CG +LI R+V+TAA C ++ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 75 GVSTVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVT 132 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 133 ILPLPLQNA---TVEAGTRCQVAGWGSQRS------GGRLSRFPRFVNVTVTPEDQCR-- 181 + LP + ++AG + +V GWG+ + G + VN+ + C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 182 ------PNNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP 226 N C +RG C GD G P V + G+ S+ G C R Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDG 239 Query: 227 --DFFTRVALFRDWIDGVLNNP 246 F+T V + WI V++ Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQF 261 >3S9B-A nrPDB Length = 234 Score = 232 bits (593), Expect = 8e-62, Method: Composition-based stats. Identities = 59/231 (25%), Positives = 100/231 (43%), Gaps = 21/231 (9%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH--FCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 +VGG + + PFL ++ C GALI+ +V+TAA C + + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC----DRRNIRIKLGMH 56 Query: 85 DLRRRERQSR-QTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 R + + N P D+ML++L R ++ + + LP ++ Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSR-- 114 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGVLTRRG 194 G+RC++ GWG + P N+ + C P +C G+L Sbjct: 115 GVGSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGR 173 Query: 195 GICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C+GD G PL+C G HG+ + PCG+ P +T+V + +WI ++ Sbjct: 174 DTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >2R0L-A nrPDB Length = 248 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 25/244 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGAYD 85 I+GG + P P+LA+I G FC G+L+H +V++AA CF P S +VVLG + Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQ-NLNDLMLLQL----DREANLTSSVTILPLPLQN 140 R ++ + Y + +DL+L++L DR A + V + LP Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 141 ATVEAGTRCQVAGWGSQRSG-GRLSRFPRFVNVTVTPEDQC----------RPNNVCTGV 189 +T AG +CQ+AGWG S R V + + +C PN +C G Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGY 179 Query: 190 LTRRGGICNGDGGTPLVCEG----LAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 + C GD G PL CE +G+ S+ G CGR P +TRVA + DWI+ + Sbjct: 180 FDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWINDRI 238 Query: 244 NNPG 247 P Sbjct: 239 RPPR 242 >1AZZ-A nrPDB Length = 226 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 74/225 (32%), Positives = 102/225 (45%), Gaps = 15/225 (6%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG +A P +P A++ +FCGG+LI +++TAA C G VVLGA+++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGA--GFVDVVLGAHNI 58 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R E S Y+ ND+ +++L LT+++ + LP + V G Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD--VGVG 116 Query: 147 TRCQVAGWG-SQRSGGRLSRFPRFVNVTVTPEDQCRP-------NNVCTGVLTRRGGICN 198 T GWG S +S R V+V + C N+C T G CN Sbjct: 117 TVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICI-DSTGGKGTCN 175 Query: 199 GDGGTPLVCEGLAHGVASFS--LGPCGRGPDFFTRVALFRDWIDG 241 GD G PL GL +G+ SF G PD FTRV F DWI Sbjct: 176 GDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQT 220 >1OP0-A nrPDB Length = 234 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 98/230 (42%), Gaps = 19/230 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + + FL + N FCGG LI+ +V+TAA C + + LG + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC----DSTDFQMQLGVHSK 56 Query: 87 RRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + N + + D+ML++LD+ ++S I PL L ++ Sbjct: 57 KVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPI--SNSKHIAPLSLPSSPPSV 114 Query: 146 GTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGG 195 G+ C++ GWGS P N+ + C+ +C G++ Sbjct: 115 GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKD 174 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+ S+ PCG+ P +T V + DWI + Sbjct: 175 TCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >4XDE-A nrPDB Length = 257 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 74/242 (30%), Positives = 100/242 (41%), Gaps = 28/242 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVLGAYD 85 +VGG A P++A++ G FC G+LI +V+TAA C Q + P TVVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREAN-----LTSSVTILPLPLQN 140 + S + P +DL LL+L +A+ L+ V + LP Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 141 ATVEAGTRCQVAGWGSQRSG-GRLSRFPRFVNVTVTPEDQCR----------PNNVCTGV 189 A T CQVAGWG Q G + F + V ++C P +C G Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGF 181 Query: 190 LTRRGGICNGDGGTPLVCEG-------LAHGVASFSLGPCG--RGPDFFTRVALFRDWID 240 L C GD G PLVCE G+ S+ G CG P +T VA + WI Sbjct: 182 LEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSG-CGDRNKPGVYTDVAYYLAWIR 240 Query: 241 GV 242 Sbjct: 241 EH 242 >1FIZ-A nrPDB Length = 263 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 59/250 (23%), Positives = 105/250 (42%), Gaps = 31/250 (12%) Query: 27 IVGGRKARPRQFPFLASIQ------NQGRHFCGGALIHARFVMTAASCFQSQNP-GVSTV 79 +VGG A P +P++ S+Q N+ H CGG L+++ +V+TAA CF+++ + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 80 VLGAYDL-----RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTIL 134 + GA ++ + + ++ F + Y +ND+ L+++ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 135 PLP-LQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQC----------RP 182 LP + A C V GWG + G R S + V + + C R Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEG------LAHGVASFSLGPC-GRGPDFFTRVALF 235 NVC G + C GD G PL+C + G+ S+ +G + P +T + Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 236 RDWIDGVLNN 245 +WI + + Sbjct: 241 LNWIASKIGS 250 >3S69-A nrPDB Length = 234 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 57/230 (24%), Positives = 96/230 (41%), Gaps = 19/230 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 ++GG + + L + N FC G LI+ +V+TAA C + + LG + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC----DNTNFQMKLGVHSK 56 Query: 87 RRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + N + + D+ML++LD ++S I+PL L ++ Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRV--SNSEHIVPLSLPSSPPSV 114 Query: 146 GTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGG 195 G+ C + GWGS P + + + C+ +C G+L Sbjct: 115 GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKD 174 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 C GD G PL+C G G+ SF PCG+ P +T+V + WI ++ Sbjct: 175 TCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >4BXW-A nrPDB Length = 423 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 59/264 (22%), Positives = 97/264 (36%), Gaps = 30/264 (11%) Query: 11 AGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCF 69 A LL S SP + IV G + + P+ A++ ++ FCGG ++ +V+TAA C Sbjct: 155 ATLLKKSD-NPSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCI 213 Query: 70 QSQNPGVSTVVLGAYDLRRRER----QSRQTFSISSMSEN----GYDPQQNLNDLMLLQL 121 +VV+G D R E + + +D D+ ++Q+ Sbjct: 214 --NETETISVVVGEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQM 271 Query: 122 DREANLTSSVTILPLPLQN---ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED 178 + +V LP + + V+G+G G S+ + + V Sbjct: 272 KTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRH 331 Query: 179 QC--------RPNNVCTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLGPCGRGP 226 C PN C G T C GD G P G+ S G C R Sbjct: 332 TCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEG-CARNG 390 Query: 227 DF--FTRVALFRDWIDGVLNNPGP 248 + +T+++ F WI ++ P Sbjct: 391 KYGNYTKLSKFIPWIKRIMRQKLP 414 >4KKD-A nrPDB Length = 433 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 68/296 (22%), Positives = 105/296 (35%), Gaps = 53/296 (17%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQG-------RHFCGG 54 L G SR+ S + I+GGR A P FP+ A I + + F G Sbjct: 132 RSLPTCLPECG--QPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSG 189 Query: 55 ALIHARFVMTAASCFQSQNPGV---------STVVLGAYDLRRRERQSRQTFSISSMSEN 105 AL+ A +++TAA +SQ TV LG +D+R + + + + Sbjct: 190 ALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHP 248 Query: 106 GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT-VEAGTRCQVAGWGSQRSG---- 160 ++ Q +D+ L+QL L V + LP VAGWG Sbjct: 249 DFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVD 308 Query: 161 -------GRLSRFPRFVNVTVTPEDQCR-------------PNNVCTGVLTRRGGICNGD 200 LS ++V + V P +C+ N C G C GD Sbjct: 309 EIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGD 368 Query: 201 GGTPLV------CEGLAHGVASF-SLGPCGRGP--DFFTRVALFRDWIDGVLNNPG 247 G V + G+ S+ CG +T+V+ + DW+ + P Sbjct: 369 SGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQ 424 >1BQY-A nrPDB Length = 234 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 56/230 (24%), Positives = 96/230 (41%), Gaps = 19/230 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 + GG + + L + N CGG LI+ +V+TAA C + ++ G + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 87 RRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + + N + D+ML++LD ++S I PL L ++ Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSV--SNSEHIAPLSLPSSPPSV 114 Query: 146 GTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQCRP---------NNVCTGVLTRRGG 195 G+ C++ GWG + P N+ + CR +C G+L Sbjct: 115 GSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRD 174 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 243 C+ D G PL+C G+ G+ S+ PCG+ P +T+V + DWI ++ Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >1FIW-A nrPDB Length = 290 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 56/250 (22%), Positives = 102/250 (40%), Gaps = 31/250 (12%) Query: 27 IVGGRKARPRQFPFLASIQ------NQGRHFCGGALIHARFVMTAASCFQ-SQNPGVSTV 79 I+GG+ A +P++ S+Q N+ H CGG+L+++++++TAA CF+ + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 80 VLGAYDLRRRE-----RQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTIL 134 + GA ++ ++ + + Y ND+ L+++ + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 135 PLPLQNA-TVEAGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQC----------RP 182 LP A C VAGWG + R S + V + C R Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEG------LAHGVASFSLGPC-GRGPDFFTRVALF 235 NVC G + C GD G PL+C+ + G+ S+ +G + P +T + Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 236 RDWIDGVLNN 245 +WI + + Sbjct: 241 LNWIASKIGS 250 >4FXG-H nrPDB Length = 242 Score = 226 bits (576), Expect = 7e-60, Method: Composition-based stats. Identities = 59/245 (24%), Positives = 103/245 (42%), Gaps = 28/245 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I GG+KA+P FP+ I G GAL++ +V+TAA Q S + + L Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 87 RRRERQSRQTFSISSMSENGY-DPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA--TV 143 +R Q +S + GY ND+ L++L+ + + S++T + LP + A + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------------RPNNVCTGV 189 +GWG + G L+R +V++ + +C N +C G+ Sbjct: 119 RTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 190 LTRRGGICNGDGGTPLVC------EGLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDG 241 + C GD G LV G+ S+ CG +T+V + WI+ Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 237 Query: 242 VLNNP 246 ++++ Sbjct: 238 IISDF 242 >1SC8-U nrPDB Length = 262 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 95/251 (37%), Gaps = 28/251 (11%) Query: 23 PLLDIVGGRKARPRQFPFLASIQNQGR-----HFCGGALIHARFVMTAASCFQSQ-NPGV 76 P I+GG P+ A+I + R + CGG+LI +V++A CF Sbjct: 12 PRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKED 71 Query: 77 STVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQ--NLNDLMLLQLD----REANLTSS 130 V LG L + + + + Y + ND+ LL++ R A + + Sbjct: 72 YIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRT 131 Query: 131 VTILPLPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQCRP------- 182 + + LP + GT C++ G+G + S L + V + +C+ Sbjct: 132 IQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSE 191 Query: 183 ---NNVCTGVLTRRGGICNGDGGTPLVC----EGLAHGVASFSLGPCGR-GPDFFTRVAL 234 +C + C GD G PLVC G+ S+ G + P +TRV+ Sbjct: 192 VTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSH 251 Query: 235 FRDWIDGVLNN 245 F WI Sbjct: 252 FLPWIRSHTKE 262 >1EQ9-A nrPDB Length = 222 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 13/227 (5%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQS-QNPGVSTVVLGAYD 85 IVGG+ A ++P+ S++ G H CG +++ V+TAA C N V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L ++ YD ND+ L+ L V + L + +E+ Sbjct: 61 LSE---SGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLES 117 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------PNNVCTGVLTRRGGICN 198 C + GWGS R GG + + + V P+ QC +++CT + R G C+ Sbjct: 118 N-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICT-LTKRGEGACH 175 Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 GD G PLV G G+ SF PD +TRV+ F WI+ L Sbjct: 176 GDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >4IGD-A nrPDB Length = 406 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 60/275 (21%), Positives = 102/275 (37%), Gaps = 41/275 (14%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQN-QGRHFCGGALIHAR 60 L + GL SR + I GR A+ P++A + + G+ FCGG+L+ + Sbjct: 134 RSLPTCLPVCGLPKFSRKL---MAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSS 190 Query: 61 FVMTAASCFQSQ--------------NPGVSTVVLGAYDLRRRERQSRQTFSISSMSENG 106 +++TAA C +P ++LG + R + + + Sbjct: 191 WIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQ 250 Query: 107 YDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRF 166 YDP ND+ L++L L + V + LP + G V+GWG Q R Sbjct: 251 YDPNTFENDVALVELLESPVLNAFVMPICLP--EGPQQEGAMVIVSGWGKQFLQ-RFPET 307 Query: 167 PRFVNVTVTPEDQCRP-----------NNVCTGVLTRRGGICNGDGGTPLVC------EG 209 + + + C+ + +C G C GD G P+V + Sbjct: 308 LMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQW 367 Query: 210 LAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGV 242 G S+ CG+ ++ + +DWI V Sbjct: 368 YLVGTVSWGD-DCGKKDRYGVYSYIHHNKDWIQRV 401 >1FON-A nrPDB Length = 240 Score = 223 bits (568), Expect = 7e-59, Method: Composition-based stats. Identities = 70/243 (28%), Positives = 97/243 (39%), Gaps = 30/243 (12%) Query: 29 GGRKARPRQFPFLASIQNQG----RHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 G A P + + S+Q + H CGG+LI +V+TA C + VVLG Y Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSR--TYQVVLGEY 58 Query: 85 DLRRRERQSRQTFSI--SSMSENGYDPQ--QNLNDLMLLQLDREANLTSSVTILPLPLQN 140 D E + ++ ND+ L++L R A L V + LP Sbjct: 59 DRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVL 190 + C ++GWG +GG L + + + C + VC G Sbjct: 119 DILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGD 178 Query: 191 TRRGGICNGDGGTPLVC-----EGLAHGVASFSLG-PCG--RGPDFFTRVALFRDWIDGV 242 TR G CNGD G PL C HGV SF C + P FTRV+ F DWID Sbjct: 179 TRSG--CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDET 236 Query: 243 LNN 245 + + Sbjct: 237 IAS 239 >5TO3-B nrPDB Length = 409 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 60/258 (23%), Positives = 102/258 (39%), Gaps = 39/258 (15%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 VVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILPL 136 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 137 PLQNA---TVEAGTRCQVAGWGSQRS------GGRLSRFPRFVNVTVTPEDQCR------ 181 P + ++AG + +V GWG+ + G + VN+ + C+ Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 182 --PNNVCTGV---LTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGRGP--DF 228 N C G +RG C GD G P V + G+ S G C R F Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAG-CDRDGKYGF 239 Query: 229 FTRVALFRDWIDGVLNNP 246 +T V + WI V++ Sbjct: 240 YTHVFRLKKWIQKVIDQF 257 >5LHN-A nrPDB Length = 247 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 58/246 (23%), Positives = 95/246 (38%), Gaps = 29/246 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQG------RHFCGGALIHARFVMTAASCFQSQNPGVSTVV 80 IVGG P+ A+I + CGG+LI +V +AA CF + VV Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGY---DPQQNLNDLMLLQLDRE----ANLTSSVTI 133 F + + + Y D ND+ LL++ A + S+ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 134 LPLPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC-RPN-------- 183 + LP + G+ C++ G+G + L + + V + +QC +P+ Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 184 -NVCTGVLTRRGGICNGDGGTPLVCE----GLAHGVASFSLGPCGR-GPDFFTRVALFRD 237 +C + C GD G PL+C G+ S+ G + P +TRV+ F D Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLD 240 Query: 238 WIDGVL 243 WI + Sbjct: 241 WIQSHI 246 >2XXL-A nrPDB Length = 408 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 57/262 (21%), Positives = 98/262 (37%), Gaps = 41/262 (15%) Query: 25 LDIVGGRKARPRQFPFLASIQNQ----GRHFCGGALIHARFVMTAASCFQSQNPGVSTVV 80 + G + + P++A ++ Q R CGGA+I R+++TAA C + + Sbjct: 117 QRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR 176 Query: 81 LGAYDLRRRERQSRQ------------TFSISSMSENGYDPQQNLNDLMLLQLDREANLT 128 LG + + E +Q + YD + ++D+ LL+L+R Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQ 236 Query: 129 SSVTILPLPLQNATVEAG---TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP--- 182 + + LP+ + E + V GWG+ G S NV + P C Sbjct: 237 KHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSACSQAYR 295 Query: 183 -----NNVCTGVLTRRGGICNGDGGTPLVC----------EGLAHGVASFSLGPCGRG-- 225 + +C G C GD G PL + + G+ S + CG+ Sbjct: 296 RAVPLSQLCVGG-GDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISL 354 Query: 226 PDFFTRVALFRDWIDGVLNNPG 247 P +T V + WI + + G Sbjct: 355 PGLYTNVGEYVQWITDTMASNG 376 >4IW4-E nrPDB Length = 279 Score = 216 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 63/271 (23%), Positives = 98/271 (36%), Gaps = 51/271 (18%) Query: 27 IVGGRKARPRQFPFLASIQNQG-------RHFCGGALIHARFVMTAASCFQSQNPGV--- 76 I+GGR A P FP+ A I + + F GAL+ A +++TAA +SQ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 77 ------STVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSS 130 TV LG +D+R + + + + ++ Q +D+ L+QL L Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 131 VTILPLPLQNAT-VEAGTRCQVAGWGSQRSG-----------GRLSRFPRFVNVTVTPED 178 V + LP VAGWG LS ++V + V P Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 179 QCR-------------PNNVCTGVLTRRGGICNGDGGTPLV------CEGLAHGVASF-S 218 +C+ N C G C GD G V + G+ S+ Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 219 LGPCGRGP--DFFTRVALFRDWIDGVLNNPG 247 CG +T+V+ + DW+ + P Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQMGLPQ 270 >1YM0-A nrPDB Length = 238 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 20/238 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGR--HFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 IVGG +ARP +FP+ S++ + HFCGG++I+ R+V+ AA C Q + P + ++V+G + Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 D + S YDP ND+ +++ +V + P Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND-Y 119 Query: 145 AGTRCQVAGWGSQRSGGR-LSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTR-- 192 + Q +GWG+ SGG R+V + +T C + +C T Sbjct: 120 VYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGMT 179 Query: 193 RGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 C GD G PL + G+ S+ +G P ++RV WI + N Sbjct: 180 DRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTITN 237 >1GPZ-A nrPDB Length = 399 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 62/271 (22%), Positives = 105/271 (38%), Gaps = 36/271 (13%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61 ++ + G I+GG+KA+ FP+ GR GGAL+ R+ Sbjct: 136 EKIPRCLPVCG---KPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRW 190 Query: 62 VMTAASCFQ-----SQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLN-- 114 ++TAA +Q+ V LG ++ + S+ Y ++ N Sbjct: 191 ILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSV-HPDYRQDESYNFE 249 Query: 115 -DLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT 173 D+ LL+L+ L ++ + LP + + G V+G+G +++ RFV + Sbjct: 250 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLP 307 Query: 174 VTPEDQCR-------------PNNVCTGVLTRRGGICNGDGGT------PLVCEGLAHGV 214 V C N C G + + C GD G P +A G+ Sbjct: 308 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGI 367 Query: 215 ASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 S+ +G C RG F+T+V + DWI + Sbjct: 368 VSWGIG-CSRGYGFYTKVLNYVDWIKKEMEE 397 >5LPF-A nrPDB Length = 234 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 62/235 (26%), Positives = 101/235 (42%), Gaps = 27/235 (11%) Query: 30 GRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRR 89 G P+ S+ N C G L+ +V+TAA C P + V L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC--GNKPLWARVGDDHLLLLQG 64 Query: 90 ERQSRQTFSISSMSENGYD--------PQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 141 E + + S+ Y + + +DLMLL+L R L V L LP + Sbjct: 65 E---QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYR-- 119 Query: 142 TVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTR 192 + G +CQVAGWG+ + + ++ ++T+ +C N +C G L R Sbjct: 120 CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDR 178 Query: 193 RGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVLNN 245 C D G PLVC+ G+ S+ + PCG + P +T++ + WI+ V+ + Sbjct: 179 GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 233 >1MD7-A nrPDB Length = 328 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 36/270 (13%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61 ++ + G I+GG+KA+ FP+ GR GGAL+ R+ Sbjct: 68 EKIPRCLPVCG---KPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRW 122 Query: 62 VMTAASCFQ-----SQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLN-- 114 ++TAA +Q+ V LG ++ + S+ Y ++ N Sbjct: 123 ILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSV-HPDYRQDESYNFE 181 Query: 115 -DLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT 173 D+ LL+L+ L ++ + LP + + G V+G+G +++ RFV + Sbjct: 182 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLP 239 Query: 174 VTPEDQCR-------------PNNVCTGVLTRRGGICNGDGGT------PLVCEGLAHGV 214 V C N C G + + C GD G P +A G+ Sbjct: 240 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGI 299 Query: 215 ASFSLGPCGRGPDFFTRVALFRDWIDGVLN 244 S+ +G C RG F+T+V + DWI + Sbjct: 300 VSWGIG-CSRGYGFYTKVLNYVDWIKKEME 328 >2QY0-B nrPDB Length = 242 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 61/246 (24%), Positives = 101/246 (41%), Gaps = 33/246 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQ-----SQNPGVSTVVL 81 I+GG+KA+ FP+ GR GGAL+ R+++TAA +Q+ V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 82 GAYDLRRRERQSRQTFSISSMSENGYDPQQNLN---DLMLLQLDREANLTSSVTILPLPL 138 G ++ + S+ Y ++ N D+ LL+L+ L ++ + LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSV-HPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPD 117 Query: 139 QNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------------PNNV 185 + + G V+G+G +++ RFV + V C N Sbjct: 118 NDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 186 CTGVLTRRGGICNGDGGT------PLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWI 239 C G + + C GD G P +A G+ S+ +G C RG F+T+V + DWI Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIG-CSRGYGFYTKVLNYVDWI 234 Query: 240 DGVLNN 245 + Sbjct: 235 KKEMEE 240 >2XRC-A nrPDB Length = 565 Score = 211 bits (539), Expect = 1e-55, Method: Composition-based stats. Identities = 53/242 (21%), Positives = 92/242 (38%), Gaps = 25/242 (10%) Query: 26 DIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGG++A+ P+ +I++ CGG I +++TAA C ++ + D Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 86 LRRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVT----ILPLPLQN 140 + + + + Y+ ND+ L+++ ++ N +P Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 440 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLT 191 + C V+GWG ++ R+ ++ V + C C G Sbjct: 441 YLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 497 Query: 192 RRGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 244 C GD G PLVC GV S+ CG+ P +T+VA + DWI + Sbjct: 498 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHVG 556 Query: 245 NP 246 P Sbjct: 557 RP 558 >4DJZ-B nrPDB Length = 251 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 55/250 (22%), Positives = 95/250 (38%), Gaps = 38/250 (15%) Query: 27 IVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQ------------- 72 I GR A+ P++A + + G+ FCGG+L+ + +++TAA C Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 73 -NPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSV 131 +P ++LG + R + + + YDP ND+ L++L L + V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 132 TILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP--------- 182 + LP + G V+GWG Q R + + + C+ Sbjct: 121 MPICLP--EGPQQEGAMVIVSGWGKQFLQ-RFPETLMEIEIPIVDHSTCQKAYAPLKKKV 177 Query: 183 --NNVCTGVLTRRGGICNGDGGTPLVC------EGLAHGVASFSLGPCGRGP--DFFTRV 232 + +C G C GD G P+V + G S+ CG+ ++ + Sbjct: 178 TRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGKKDRYGVYSYI 236 Query: 233 ALFRDWIDGV 242 +DWI V Sbjct: 237 HHNKDWIQRV 246 >5XRF-A nrPDB Length = 242 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 62/235 (26%), Positives = 106/235 (45%), Gaps = 27/235 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQ--GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 ++GG + + FLA+ C G LIH +V+ AA C++ + LG + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYK----RGLNIYLGMH 62 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQN----LNDLMLLQLDREANLTSSVTILPLPLQN 140 + + ++ ++I E+ Y + D++LL+L++ ++S I PL L + Sbjct: 63 NQSIQFDDEQRRYAIE---EHYYRCDEKLTKWEKDVVLLKLNKPV--SNSTHIAPLSLPS 117 Query: 141 ATVEAGTRCQVAGWGSQRSG-GRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVL 190 + G+ C+V GWG S L P N+ + +C + +C GVL Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVL 177 Query: 191 TRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVL 243 CN D G PL+C+G G+ F PC + P +TRV+ + DWI ++ Sbjct: 178 EGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >5O32-I nrPDB Length = 244 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 25/241 (10%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG++A+ P+ +I++ CGG I +++TAA C ++ + D Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 87 RRRERQSRQTFSISSMS-ENGYDPQQNLNDLMLLQLDREANLTSSVT----ILPLPLQNA 141 + + + + Y+ ND+ L+++ ++ N +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 142 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTR 192 + C V+GWG ++ R+ ++ V + C C G Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDG 177 Query: 193 RGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNN 245 C GD G PLVC GV S+ CG+ P +T+VA + DWI + Sbjct: 178 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHVGR 236 Query: 246 P 246 P Sbjct: 237 P 237 >4LK4-A nrPDB Length = 357 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 64/243 (26%), Positives = 105/243 (43%), Gaps = 28/243 (11%) Query: 26 DIVGGRKARPRQFPFLASIQNQG-----RHFCGGALIHARFVMTAASCFQSQNPGVSTVV 80 I+ G A ++P + ++ +G FCGG+ + R+V+TAA CF S++ V+ Sbjct: 10 RIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDVI 69 Query: 81 LGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140 +GAYDL Q + + Y P LND+ +++L + ++L + L P Sbjct: 70 IGAYDLNNSS-QGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPA--ITLAGPATR 126 Query: 141 ATVEAGTRCQVAGWGSQ--RSGGRLSRFPRFVNVTVTPEDQCR------------PNNVC 186 ++ A T VAGWG + + + V+V + + C+ N C Sbjct: 127 TSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTNFC 186 Query: 187 TGVLTRRGGICNGDGGTPLVCEG--LAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGV 242 LT C GD G P+V + G+ S+ C + +T V+ FRDWI Sbjct: 187 AARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWITKH 244 Query: 243 LNN 245 N Sbjct: 245 TNQ 247 >2OLG-A nrPDB Length = 278 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 69/273 (25%), Positives = 110/273 (40%), Gaps = 43/273 (15%) Query: 13 LLASSRAGSSPLLDIVGGRKARPRQFPFLASI-----QNQGRHFCGGALIHARFVMTAAS 67 LL + I+ G P +FP+ A I N + CGG+LI+ R+++TAA Sbjct: 9 LLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAH 68 Query: 68 CFQSQNPGVS----TVVLGAYDLRRRER-----------QSRQTFSISSMSENGY--DPQ 110 C + V V LG ++ + ++ Y + Sbjct: 69 CVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSK 128 Query: 111 QNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFV 170 +D+ L++L+R+ T+ + + LP N V+ G R V GWG G+ S + + Sbjct: 129 DRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKL 187 Query: 171 NVTVTPEDQC-----------RPNNVCTGVLTRRGGICNGDGGTPLVCEG-----LAHGV 214 V V +QC R + +C G + C GD G PL+ E G+ Sbjct: 188 AVPVVHAEQCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGL 246 Query: 215 ASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245 SF CG P +T+V +RDWI+G + Sbjct: 247 VSFGA-TCGTEGWPGIYTKVGKYRDWIEGNIRP 278 >5KWM-A nrPDB Length = 230 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 58/223 (26%), Positives = 83/223 (37%), Gaps = 19/223 (8%) Query: 27 IVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IVGG A + PF ++ G+ FCGG L V+TAA C P VV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT-VE 144 + E + ++ Y D+ +L L+ + L + Sbjct: 61 MSSNEGTVSKVTNV--WVHPEYQDAAKGFDVSVLTLEAPVK----EAPIELAKADDAGYA 114 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN--------NVCTGVLTRRGGI 196 T + GWG+ GG+ + + V V +D C+ VC GV Sbjct: 115 PDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDT 174 Query: 197 CNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRD 237 C GD G P+V GV S+ G C R P + RV + D Sbjct: 175 CQGDSGGPMVVNNKLIGVTSWGEG-CARPGKPGVYARVGAYYD 216 >6BQM-A nrPDB Length = 506 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 33/244 (13%) Query: 26 DIVGGRKARPRQFPFLASI--QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 I+GG +A ++P++ ++ +N FCGG+ + R+V+TAA C ++P V+LGA Sbjct: 10 RIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLGA 69 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +D+ + + N Y ND+ +L+L+R+ SV I N + Sbjct: 70 FDMNDVN-TAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDFNE-L 127 Query: 144 EAGTRCQVAGWGSQRSGGR----LSRFPRFVNVTVTPEDQCRP----------------N 183 + V G+G+++ + V V P +C+ N Sbjct: 128 TKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQLTNN 187 Query: 184 NVCTGVLTRRGGICNGDGGTPLVCEG----LAHGVASFSLGPCGRG--PDFFTRVALFRD 237 C G C+GD G P+ + GV S+ G CGR P +T +++F D Sbjct: 188 AFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGDG-CGRANSPGVYTNLSVFND 244 Query: 238 WIDG 241 W+D Sbjct: 245 WLDD 248 >2B9L-A nrPDB Length = 394 Score = 206 bits (524), Expect = 8e-54, Method: Composition-based stats. Identities = 69/269 (25%), Positives = 113/269 (42%), Gaps = 42/269 (15%) Query: 18 RAGSSPLLDIVGGR-KARPRQFPFLASI--------QNQGRHFCGGALIHARFVMTAASC 68 R I G +A +FP++ ++ + + CGG+LI V+T A C Sbjct: 121 RNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHC 180 Query: 69 FQS--QNPGVSTVVLGAYD-LRRRERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLDRE 124 S N + G +D L +ER Q I + + ++P+ +ND+ LL LDR Sbjct: 181 VNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRP 240 Query: 125 ANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGG--RLSRFPRFVNVTVTPEDQCRP 182 ++ + LP Q+ ++ T C +GWG + G R S + + + D+C+ Sbjct: 241 LVQADNIGTICLPQQSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQA 299 Query: 183 N---------------NVCTGVLTRRGGICNGDGGTPLVCEG-------LAHGVASFSLG 220 + VC G + C GDGG+PL C + G+ ++ +G Sbjct: 300 DLRNTRLGLKFVLDQTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIG 358 Query: 221 PCGRG--PDFFTRVALFRDWIDGVLNNPG 247 CG P + VA FR+WID + G Sbjct: 359 -CGDENVPGVYANVAHFRNWIDQEMQAKG 386 >1ELV-A nrPDB Length = 333 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 59/276 (21%), Positives = 99/276 (35%), Gaps = 46/276 (16%) Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVM 63 L + G+ R I+GG A + FP+ N GGALI+ +V+ Sbjct: 63 LPKCVPVCGV---PREPFEEKQRIIGGSDADIKNFPWQVFFDNPWA---GGALINEYWVL 116 Query: 64 TAASCFQSQNPGVSTVVLGAYDLR-RRERQSRQTFSISSMSENGY-------DPQQNLND 115 TAA + T+ +G+ ++ R +S+ G+ ND Sbjct: 117 TAAHVVEGNREP--TMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDND 174 Query: 116 LMLLQLDREANLTSSVTILPLP--LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT 173 + L++L + +V+ + LP + + G ++GWG R R + + Sbjct: 175 IALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLP 233 Query: 174 VTPEDQCR-----------------PNNVCTGVLTRRGGICNGDGGTPLVCEG------- 209 V P +C+ PN +C G + C GD G + Sbjct: 234 VAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKF 292 Query: 210 LAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 A G+ S+ CG +TRV + DWI + Sbjct: 293 YAAGLVSWGP-QCGTY-GLYTRVKNYVDWIMKTMQE 326 >5UBM-A nrPDB Length = 252 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 56/254 (22%), Positives = 94/254 (37%), Gaps = 43/254 (16%) Query: 26 DIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 I+GG A + FP+ N GGALI+ +V+TAA + T+ +G+ Sbjct: 1 RIIGGSDADIKNFPWQVFFDNPWA---GGALINEYWVLTAAHVVEGNREP--TMYVGSTS 55 Query: 86 LR-RRERQSRQTFSISSMSENGY-------DPQQNLNDLMLLQLDREANLTSSVTILPLP 137 ++ R +S+ G+ ND+ L++L + +V+ + LP Sbjct: 56 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 115 Query: 138 --LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-------------- 181 + + G ++GWG R R + + V P +C+ Sbjct: 116 GTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLPVAPLRKCKEVKVEKPTADAEAY 174 Query: 182 ---PNNVCTGVLTRRGGICNGDGGTPLVCEG-------LAHGVASFSLGPCGRGPDFFTR 231 PN +C G + C GD G + A G+ S+ CG +TR Sbjct: 175 VFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QCGTY-GLYTR 231 Query: 232 VALFRDWIDGVLNN 245 V + DWI + Sbjct: 232 VKNYVDWIMKTMQE 245 >3I77-A nrPDB Length = 230 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 64/232 (27%), Positives = 93/232 (40%), Gaps = 28/232 (12%) Query: 27 IVGGRKARPRQFPFLASIQNQGRH-FCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAY 84 +VGG +A +FPF+ + N+ FCGGAL V+TAA C N T G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144 DL+ + + S + G+ + D L++L + N + L + T Sbjct: 61 DLQ--SSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPT------LKIATTTAY 112 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVL-TRRG 194 VAGWG+ R GG R+ NV + CR + +C G T Sbjct: 113 NQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGV 172 Query: 195 GICNGDGGTPL-----VCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWI 239 C GD G P+ E + G+ S+ G C R P +T V+ F I Sbjct: 173 DTCQGDSGGPMFRKDNADEWIQVGIVSWGYG-CARPGYPGVYTEVSTFASAI 223 >4J1Y-A nrPDB Length = 397 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 58/276 (21%), Positives = 98/276 (35%), Gaps = 46/276 (16%) Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVM 63 L + G+ R +GG A + FP+ N GGALI+ +V+ Sbjct: 127 LPKCVPVCGV---PREPFEEKARAIGGSDADIKNFPWQVFFDNPWA---GGALINEYWVL 180 Query: 64 TAASCFQSQNPGVSTVVLGAYDLR-RRERQSRQTFSISSMSENGY-------DPQQNLND 115 TAA + T+ +G+ ++ R +S+ G+ ND Sbjct: 181 TAAHVVEGNREP--TMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDND 238 Query: 116 LMLLQLDREANLTSSVTILPLP--LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT 173 + L++L + +V+ + LP + + G ++GWG R R + + Sbjct: 239 IALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLP 297 Query: 174 VTPEDQCR-----------------PNNVCTGVLTRRGGICNGDGGTPLVCEG------- 209 V P +C+ PN +C G + C GD G + Sbjct: 298 VAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKF 356 Query: 210 LAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 A G+ S+ CG +TRV + DWI + Sbjct: 357 YAAGLVSWGP-QCGTY-GLYTRVKNYVDWIMKTMQE 390 >3BEU-A nrPDB Length = 224 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 61/230 (26%), Positives = 91/230 (39%), Gaps = 30/230 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAYD 85 +VGG +A +FPF+ + CGGAL V+TAA C N T G D Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L+ + + S + G+ + D L++L + N + L + T Sbjct: 57 LQ--SSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPT------LKIATTTAYN 108 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTRRGGI 196 VAGWG+ R GG R+ NV + CR + +C G T++ Sbjct: 109 QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDT 168 Query: 197 CNGDGGTPL-----VCEGLAHGVASFSLGPCGRGP--DFFTRVALFRDWI 239 C GD G P+ E + G+ S+ G C R +T V+ F I Sbjct: 169 CQGDSGGPMFRKDNADEWVQVGIVSWGEG-CARKGKYGVYTEVSTFASAI 217 >1PQ7-A nrPDB Length = 224 Score = 193 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 63/228 (27%), Positives = 86/228 (37%), Gaps = 19/228 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 IVGG A FPF+ SI G +CGG+L++A V+TAA C + G+ Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLS- 59 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146 R + S Y N NDL +L+L ++ L + AG Sbjct: 60 --RTSGGITSSLSSVRVHPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSDPVAG 115 Query: 147 TRCQVAGWGSQRSGGRLSRF-PRFVNVTVTPEDQCRP---------NNVCTGVLTRRGGI 196 + VAGWG+ GG + V V + CR C GV + Sbjct: 116 SSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDS 175 Query: 197 CNGDGGTPLVC-EGLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDG 241 C GD G P+V G S+ G C R + V R +ID Sbjct: 176 CQGDSGGPIVDSSNTLIGAVSWGNG-CARPNYSGVYASVGALRSFIDT 222 >1SI5-H nrPDB Length = 240 Score = 193 bits (491), Expect = 7e-50, Method: Composition-based stats. Identities = 63/235 (26%), Positives = 106/235 (45%), Gaps = 27/235 (11%) Query: 27 IVGG--RKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAY 84 +V G + ++ S++ + +H CGG+LI +V+TA CF S++ LG + Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 85 DLR-RRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 D+ R + + +Q ++S + Y P+ + DL+L++L R A L V+ + LP +T+ Sbjct: 58 DVHGRGDEKCKQVLNVSQLV---YGPEGS--DLVLMKLARPAVLDDFVSTIDLPNYGSTI 112 Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN----------VCTGVLTRR 193 T C V GWG R ++ + ++C ++ +C G Sbjct: 113 PEKTSCSVYGWGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG 171 Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGP---CG--RGPDFFTRVALFRDWIDGVL 243 G C GD G PLVCE + + P C P F RVA + WI ++ Sbjct: 172 SGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >2ASU-B nrPDB Length = 234 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 66/232 (28%), Positives = 109/232 (46%), Gaps = 20/232 (8%) Query: 27 IVGGRKARPRQFPFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 +VGG P P+ S++N QG+HFCGG+L+ ++++TA CF S + ++ + Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L + + + +++ P + L+LL+L+R L V ++ LP + V Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGSQ--LVLLKLERSVTLNQRVALICLPPEWYVVPP 115 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 197 GT+C++AGWG + G + + V +C R + +CT L G C Sbjct: 116 GTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGAC 174 Query: 198 NGDGGTPLVC----EGLAHGVASFSLGPC-GRGPDFFTRVALFRDWIDGVLN 244 GD G PL C + G+ + R P FTRV++F DWI V+ Sbjct: 175 EGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >2FMJ-A nrPDB Length = 222 Score = 188 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 62/230 (26%), Positives = 88/230 (38%), Gaps = 32/230 (13%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQ-NPGVSTVVLGAYD 85 +VGG +A +FPF+ + CGGAL V+TAA C N T G D Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 L+ + + S + GY+ D L++L + N + L + T Sbjct: 57 LQ--SSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPINQPT------LKIATTTAYN 106 Query: 146 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGGI 196 VAGWG+ R GG R+ NV + CR +C G T Sbjct: 107 QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDT 166 Query: 197 CNGDGGTPL-----VCEGLAHGVASFSLGPCGRGP--DFFTRVALFRDWI 239 C GD G P+ E + G+ S+ G C R +T V+ F I Sbjct: 167 CQGDSGGPMFRKDNADEWIQVGIVSWGEG-CARKGKYGVYTEVSTFASAI 215 >3H7O-A nrPDB Length = 228 Score = 188 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 54/231 (23%), Positives = 91/231 (39%), Gaps = 17/231 (7%) Query: 29 GGRKARPRQFPFLASIQN---QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 GG K +Q P+ +++ + CGGA++ FV+TAA C Q P T+V+ Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPE--TIVIQYES 59 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTS-SVTILPLPLQNATVE 144 E + +S + + Y + ND+ +L+L R L LP + Sbjct: 60 TNLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRRGG 195 G+ V+G+G ++ + +TV D+CR C + Sbjct: 120 TGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLE 179 Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNP 246 GD G P V + GVA++ P+ FT+V + WI ++ Sbjct: 180 S--GDAGDPTVQQDTLVGVAAYFPKRPEGAPEVFTKVGSYVSWIQDIIKKK 228 >3H7T-A nrPDB Length = 235 Score = 184 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 54/235 (22%), Positives = 81/235 (34%), Gaps = 19/235 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GG+K+ + P+ + + FCGG+++ A FV+TAA C P ++ G Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYG---- 56 Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSS-VTILPLPLQNATVEA 145 + + Y P N+ +++ + L + LP E Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEP 116 Query: 146 GTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPNN-------------VCTGVLT 191 T V+GWGS S N TV C C G Sbjct: 117 DTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEY 176 Query: 192 RRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNP 246 I GD G P V G GVAS+ P F RV + I +++ Sbjct: 177 DETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDIISGK 231 >2HLC-A nrPDB Length = 230 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 59/234 (25%), Positives = 96/234 (41%), Gaps = 29/234 (12%) Query: 27 IVGGRKARPRQFPFLA----SIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82 I+ G +A FP+ A ++Q+Q R +CGG+LI ++++TAA C V LG Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDA--VSVVVYLG 58 Query: 83 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 142 + + S +S + ++P LND+ L+++ T ++ + LP Sbjct: 59 S---AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEEL 114 Query: 143 VE--AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLT 191 V+GWG + + ++ V D+C + +C G + Sbjct: 115 NNKFENIWATVSGWGQSNTDTVI---LQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTS 170 Query: 192 RRGGICNGDGGTPLV--CEGLAHGVASF--SLGPCGRGPDFFTRVALFRDWIDG 241 C GD G P V + L GV SF G P F+RV + DWI Sbjct: 171 DGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >1M9U-A nrPDB Length = 241 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 64/239 (26%), Positives = 98/239 (41%), Gaps = 28/239 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 ++GG A P +FP+ S Q Q H CG +L+ + ++A+ C P V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 84 YDLRRRERQSRQTFSISSMS-ENGYDPQQ--NLNDLMLLQLDREANLTSSVTILPLPLQN 140 + ++ + QT ++ S + Y ND+ +L L +L ++ LP N Sbjct: 61 W--QQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 141 ATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP------------NNVCTG 188 AGT C ++GWG L + ++ V QC N++C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 189 VLTRRGGICNGDGGTPLVCE-------GLAHGVASFSLGPC-GRGPDFFTRVALFRDWI 239 G CNGD G PL C G+ V S LG C P +TRV+ + WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 >5XW8-A nrPDB Length = 133 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 7/135 (5%) Query: 24 LLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 83 IVGG P+ S+ N G HFCGG+LI++++V++AA C++S+ V LG Sbjct: 6 DDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGE 60 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143 +++ E + + ++ ++ ND+ML++L A L S V + LP + Sbjct: 61 HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR--SCA 118 Query: 144 EAGTRCQVAGWGSQR 158 AGT C ++GWG+ + Sbjct: 119 AAGTECLISGWGNTK 133 >2PKA-B nrPDB Length = 152 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 47/149 (31%), Positives = 70/149 (46%), Gaps = 15/149 (10%) Query: 108 DPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGG---RLS 164 D + +DLMLL+L A +T +V +L LP Q E G+ C+ +GWGS G Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQE--PELGSTCEASGWGSIEPGPDDFEFP 59 Query: 165 RFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVAS 216 + V +T+ C + +C G L C GD G PL+C G+ G+ S Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITS 119 Query: 217 FSLGPCG--RGPDFFTRVALFRDWIDGVL 243 + PCG P +T++ + DWID + Sbjct: 120 WGHTPCGSANKPSIYTKLIFYLDWIDDTI 148 >3VGC-B nrPDB Length = 131 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 4/134 (2%) Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD 85 IV G +A P +P+ S+Q++ G HFCGG+LI+ +V+TAA C VV G +D Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVVAGEFD 57 Query: 86 LRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 145 + ++ + Y+ ND+ LL+L A+ + +V+ + LP + A Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 117 Query: 146 GTRCQVAGWGSQRS 159 GT C GWG R Sbjct: 118 GTTCVTTGWGLTRY 131 >4WJG-C nrPDB Length = 315 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 48/272 (17%), Positives = 96/272 (35%), Gaps = 40/272 (14%) Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62 +L + G + ++P+ I+GG FP+ A + + G LI+ +++ Sbjct: 50 KLPECEAVCG---KPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWL 106 Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122 +T A + +T A L + + + Y D+ L++L Sbjct: 107 LTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLK 162 Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-- 180 ++ ++ V + LP ++ E G V+GWG + + + ++V + V +DQC Sbjct: 163 QKVSVNERVMPICLPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIR 220 Query: 181 -----------------------RPNNVCTGVLTRRGGICNGDGGTPLVCE------GLA 211 + C G+ + C GD G+ A Sbjct: 221 HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYA 280 Query: 212 HGVASFSLGPCGRGPDFFTRVALFRDWIDGVL 243 G+ SF + +V +DW+ + Sbjct: 281 TGILSFDKSCAVAEYGVYVKVTSIQDWVQKTI 312 >2JET-B nrPDB Length = 128 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Query: 30 GRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR 88 G A P +P+ S+Q++ G HFCGG+LI +V+TAA C VV G +D Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC---GVKTSDVVVAGEFDQGS 57 Query: 89 RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTR 148 E + ++ ND+ LL+L A + +V+ + LP + GT Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 149 CQVAGWGSQRS 159 C GWG + Sbjct: 118 CATTGWGKTKY 128 >4X0L-C nrPDB Length = 259 Score = 154 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 46/259 (17%), Positives = 92/259 (35%), Gaps = 37/259 (14%) Query: 16 SSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG 75 + ++P+ I+GG FP+ A + + G LI+ ++++T A + Sbjct: 4 KPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSE 63 Query: 76 VSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILP 135 +T A L + + + Y D+ L++L ++ ++ V + Sbjct: 64 NATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPIC 119 Query: 136 LPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------------- 180 LP ++ E G V+GWG + + + ++V + V +DQC Sbjct: 120 LPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTP 177 Query: 181 ----------RPNNVCTGVLTRRGGICNGDGGTPLVCE------GLAHGVASFSLGPCGR 224 + C G+ + C GD G+ A G+ SF Sbjct: 178 KSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVA 237 Query: 225 GPDFFTRVALFRDWIDGVL 243 + +V +DW+ + Sbjct: 238 EYGVYVKVTSIQDWVQKTI 256 >4F4O-C nrPDB Length = 347 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 47/275 (17%), Positives = 94/275 (34%), Gaps = 40/275 (14%) Query: 2 TRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61 +L + G + + I+GG FP+ A + + G LI+ ++ Sbjct: 81 EKLPECEAVCG---KPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQW 137 Query: 62 VMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQL 121 ++T A + + + A LR + ++ + P + D+ L++L Sbjct: 138 LLTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFH----PDNSTVDIGLIKL 193 Query: 122 DREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC- 180 ++ + V + LP ++ V G V+GWG + + ++V + V +++C Sbjct: 194 KQKVPVNERVMPICLPSKDY-VNVGLVGYVSGWGRNANL-NFTEHLKYVMLPVADQEKCV 251 Query: 181 ------------------------RPNNVCTGVLTRRGGICNGDGGTPLVCE------GL 210 + C G+ + C GD G+ Sbjct: 252 QYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWY 311 Query: 211 AHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 245 A G+ SF + RV DWI + + Sbjct: 312 AAGILSFDKSCRTAEYGVYVRVTSILDWIQTTIAD 346 >1RIW-B nrPDB Length = 147 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 13/147 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 VVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILPL 136 V +G + R ER + + + Y+ ++NL+ D+ L++L + + + + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 137 PLQNA---TVEAGTRCQVAGWGSQRSG 160 P + ++AG + +V GWG+ + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 13/150 (8%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G+ A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 79 VVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLN-DLMLLQLDREANLTSSVTILPL 136 V +G + R ER+ + + + Y+ ++NL+ D+ LL+L R L+ + + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 137 PLQNA---TVEAGTRCQVAGWGSQRSGGRL 163 P + + AG + +V GWG++R Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTT 150 >1AKS-B nrPDB Length = 98 Score = 123 bits (308), Expect = 9e-29, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 158 RSGGRLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGICNGDGGTPLVCEG 209 SG + + V C+ N +C G L C GD G P+VC G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 210 LAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 G+ S+ G + P +T+V + +WI + Sbjct: 61 QLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >2KAI-A nrPDB Length = 80 Score = 111 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86 I+GGR+ P+ +I + CGG L++ ++V+TAA C V LG ++L Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVWLGRHNL 56 Query: 87 RRRERQSRQTFSISSMSENGYD 108 E ++ + G++ Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >2WIN-I nrPDB Length = 507 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 79/249 (31%), Gaps = 79/249 (31%) Query: 33 ARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR 88 + P+ A I ++G C GA++ FV+TAA CF TV + ++ Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF--------TVDDKEHSIKV 280 Query: 89 RERQSRQTFSISSM-SENGYD---------PQQNLNDLMLLQLDREANLTSSVTILPLPL 138 ++ I + Y+ P+ D+ L++L + ++ + LP Sbjct: 281 SVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 340 Query: 139 QNAT-----VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQ-------------- 179 T + T CQ Q+ L + + E++ Sbjct: 341 TEGTTRALRLPPTTTCQ------QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGD 392 Query: 180 ----CR--------------------PNNVCTGVLTRRGG--ICNGDGGTPLVCEG---- 209 C P +CTG ++ C GD G PL+ Sbjct: 393 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRF 452 Query: 210 LAHGVASFS 218 + GV S+ Sbjct: 453 IQVGVISWG 461 >1DLE-A nrPDB Length = 298 Score = 107 bits (269), Expect = 3e-24, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 79/249 (31%), Gaps = 79/249 (31%) Query: 33 ARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR 88 + P+ A I ++G C GA++ FV+TAA CF TV + ++ Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF--------TVDDKEHSIKV 73 Query: 89 RERQSRQTFSISSM-SENGYD---------PQQNLNDLMLLQLDREANLTSSVTILPLPL 138 ++ I + Y+ P+ D+ L++L + ++ + LP Sbjct: 74 SVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 133 Query: 139 QNAT-----VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQ-------------- 179 T + T CQ Q+ L + + E++ Sbjct: 134 TEGTTRALRLPPTTTCQ------QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGD 185 Query: 180 ----CR--------------------PNNVCTGVLTRRGG--ICNGDGGTPLVCEG---- 209 C P +CTG ++ C GD G PL+ Sbjct: 186 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRF 245 Query: 210 LAHGVASFS 218 + GV S+ Sbjct: 246 IQVGVISWG 254 >2I6S-A nrPDB Length = 517 Score = 107 bits (267), Expect = 5e-24, Method: Composition-based stats. Identities = 43/250 (17%), Positives = 84/250 (33%), Gaps = 64/250 (25%) Query: 28 VGGRKARPRQF---PFLASIQNQGRHFCGGALIHARFVMTAASCF-QSQNPGVSTVVLGA 83 VG A P+ +I+ + + C GALI ++V+TAA CF + + V +G Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG- 288 Query: 84 YDLRRRERQSRQTFSISSMSENGYDPQQNLN---------DLMLLQLDREANLTSSVTIL 134 + + ++ ++ G+D N D+ LL+L ++ +++ + Sbjct: 289 ---DPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPI 345 Query: 135 PLP-LQNATV----EAGTRCQVAGWGSQRSGGRLSRFP--------RFVNVT-------- 173 LP A + G+ C+ + P +N+ Sbjct: 346 CLPCTMEANLALRRPQGSTCR----DHENELLNKQSVPAHFVALNGSKLNINLKMGVEWT 401 Query: 174 ----VTPEDQ------------CRPNNVCTGVLTRRGGICNGDGGTPLVCEG----LAHG 213 V +++ +C+G C G+ G + E G Sbjct: 402 SCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDES-PCKGESGGAVFLERRFRFFQVG 460 Query: 214 VASFS-LGPC 222 + S+ PC Sbjct: 461 LVSWGLYNPC 470 >2OK5-A nrPDB Length = 752 Score = 106 bits (265), Expect = 9e-24, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 79/249 (31%), Gaps = 79/249 (31%) Query: 33 ARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR 88 + P+ A I ++G C GA++ FV+TAA CF TV + ++ Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF--------TVDDKEHSIKV 524 Query: 89 RERQSRQTFSISSM-SENGYD---------PQQNLNDLMLLQLDREANLTSSVTILPLPL 138 ++ I + Y+ P+ D+ L++L + ++ + LP Sbjct: 525 SVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 584 Query: 139 QNAT-----VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQ-------------- 179 T + T CQ Q+ L + + E++ Sbjct: 585 TEGTTRALRLPPTTTCQ------QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGD 636 Query: 180 ----CR--------------------PNNVCTGVLTRRGG--ICNGDGGTPLVCEG---- 209 C P +CTG ++ C GD G PL+ Sbjct: 637 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRF 696 Query: 210 LAHGVASFS 218 + GV S+ Sbjct: 697 IQVGVISWG 705 >1EPT-B nrPDB Length = 82 Score = 102 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 75 GVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTIL 134 V LG +++ E + + ++ ++ ND+ML++L A L S V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 135 PLPLQNATVEAGTRCQVAGWGSQR 158 LP + AGT C ++GWG+ + Sbjct: 61 SLPR--SCAAAGTECLISGWGNTK 82 >2HNT-F nrPDB Length = 105 Score = 99.1 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 20/104 (19%) Query: 163 LSRFPRFVNVTVTPEDQCRP--------NNVCTGV---LTRRGGICNGDGGTPLVCE--- 208 + VN+ + C+ N C G +RG C GD G P V + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 209 ---GLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGVLNNPG 247 G+ S+ G C R F+T V + WI V++ G Sbjct: 62 NNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDQFG 104 >1BBR-E nrPDB Length = 109 Score = 98.0 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 37/104 (35%), Gaps = 20/104 (19%) Query: 163 LSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTR---RGGICNGDGGTPLVCE--- 208 + VN+ + C+ N C G RG C GD G P V + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 209 ---GLAHGVASFSLGPCGRGP--DFFTRVALFRDWIDGVLNNPG 247 G+ S+ G C R F+T V + WI V++ G Sbjct: 66 NNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVIDRLG 108 >2JET-C nrPDB Length = 99 Score = 91.8 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 34/96 (35%), Gaps = 15/96 (15%) Query: 162 RLSRFPRFVNVTVTPEDQCRPN--------NVCTGVLTRRGGICNGDGGTPLVCE----G 209 + + + + E C+ + C G C GD G PLVC+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKDGVW 61 Query: 210 LAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVLN 244 G+ S+ G C P ++RV W+ +L Sbjct: 62 TLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILE 97 >3RU4-E nrPDB Length = 96 Score = 91.0 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 31/95 (32%), Gaps = 15/95 (15%) Query: 162 RLSRFPRFVNVTVTPEDQCRP--------NNVCTGVLTRRGGICNGDGGTPLVCE----G 209 + ++ + C+ +C G C GD G PLVC+ Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAW 58 Query: 210 LAHGVASFSLGPCGR-GPDFFTRVALFRDWIDGVL 243 G+ S+ C P + RV +W+ L Sbjct: 59 TLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >3F1S-B nrPDB Length = 283 Score = 90.6 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 49/224 (21%), Positives = 76/224 (33%), Gaps = 30/224 (13%) Query: 39 PFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTF 97 P+ + N +G+ FCGG +I FV+T A C S TV R + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITV---KTYFNRTSQDPLMIK 119 Query: 98 SISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGW 154 YD NDL LL+L+ + + P ++ + TR ++GW Sbjct: 120 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 179 Query: 155 GS--QRSGGRLSRFP----------RFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGG 202 G L+ P + +NVTVT C ++V + G Sbjct: 180 ARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG 239 Query: 203 TPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLN 244 GV P G T+V+ + W ++N Sbjct: 240 -----SWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIMN 276 >3H5C-B nrPDB Length = 317 Score = 88.3 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 49/224 (21%), Positives = 76/224 (33%), Gaps = 30/224 (13%) Query: 39 PFLASIQN-QGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTF 97 P+ + N +G+ FCGG +I FV+T A C S TV R + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITV---KTYFNRTSQDPLMIK 160 Query: 98 SISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN---ATVEAGTRCQVAGW 154 YD NDL LL+L+ + + P ++ + TR ++GW Sbjct: 161 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 220 Query: 155 GS--QRSGGRLSRFP----------RFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGG 202 G L+ P + +NVTVT C ++V + G Sbjct: 221 ARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG 280 Query: 203 TPLVCEGLAHGVASFSLGPCGRGPD--FFTRVALFRDWIDGVLN 244 GV P G T+V+ + W ++N Sbjct: 281 -----SWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIMN 317 >2HNT-C nrPDB Length = 70 Score = 76.4 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 8/70 (11%) Query: 27 IVGGRKARPRQFPFLASIQNQG--RHFCGGALIHARFVMTAASCF------QSQNPGVST 78 IV G A P+ + + CG +LI R+V+TAA C ++ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 VVLGAYDLRR 88 V +G + R Sbjct: 61 VRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 74.5 bits (182), Expect = 4e-14, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 93 SRQTFSISSMSENGYDPQQNLN-DLMLLQLDREANLTSSVTILPLPLQNA---TVEAGTR 148 + + Y+ ++NL+ D+ L++L + + + + LP + ++AG + Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 149 CQVAGWGSQRSGGR 162 +V GWG+ + Sbjct: 63 GRVTGWGNLKETWT 76 >1P3E-A nrPDB Length = 215 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 40/203 (19%), Positives = 75/203 (36%), Gaps = 30/203 (14%) Query: 48 GRHFCGGALIHARFVMTAASCFQSQNPGVS----TVVLGAYDLRRRERQSRQTFSISSMS 103 G C G LI ++T C + +V G D + T Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMT---EFYV 84 Query: 104 ENGY-DPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGW-G-SQRSG 160 +GY + + D +++ D N+ ++V + + T GT +++G+ G RS Sbjct: 85 PSGYINTGASQYDFAVIKTDT--NIGNTVGYRSI--RQVTNLTGTTIKISGYPGDKMRST 140 Query: 161 GRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV-CEGLAHGV--ASF 217 G++S++ +VT + +G+ G+ ++ GV A + Sbjct: 141 GKVSQWEMSGSVTREDTNLAYYT----------IDTFSGNSGSAMLDQNQQIVGVHNAGY 190 Query: 218 SLGPCGRGPDFFTRVALFRDWID 240 S G GP A F ++I+ Sbjct: 191 SNGTINGGPKA---TAAFVEFIN 210 >2OUA-A nrPDB Length = 188 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 32/178 (17%), Positives = 51/178 (28%), Gaps = 48/178 (26%) Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122 +TA C G+ + R F S ND ++ Sbjct: 31 VTAGHC-------------GSVGTQVSIGNGRGVFERSVFP---------GNDAAFVRGT 68 Query: 123 REANLTSSVT------ILPLPLQNATVEAGTRCQ---VAGW--GSQRSGGRLSRFPRFVN 171 LT+ V+ + + C+ GW G+ ++ + +P+ Sbjct: 69 SNFTLTNLVSRYNSGGYATVSGSSTAPIGSQVCRSGSTTGWYCGTIQARNQTVSYPQG-- 126 Query: 172 VTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFF 229 TV + +VC GD G + A GV S G C G F Sbjct: 127 -TVHSLTR---TSVCAEP---------GDSGGSFISGTQAQGVTSGGSGNCRTGGTTF 171 >2EA3-A nrPDB Length = 189 Score = 35.9 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 13/31 (41%) Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRGPDFF 229 GD G L+ A GV S G C G F Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGGTTF 165 >2PFE-A nrPDB Length = 186 Score = 35.9 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 11/24 (45%) Query: 199 GDGGTPLVCEGLAHGVASFSLGPC 222 GD G P + A GV S G C Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDC 161 >1DUE-A nrPDB Length = 242 Score = 33.6 bits (76), Expect = 0.075, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 41/114 (35%), Gaps = 4/114 (3%) Query: 44 IQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMS 103 + +G+ G LI V+T + N S V + + + Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVK 108 Query: 104 ENGYDPQQNLNDLMLLQLDRE---ANLTSSVTILPLPLQNATVEAGTRCQVAGW 154 E +P DL L++L + +L ++ + + ++ G + ++ G+ Sbjct: 109 EILQEPFGAGVDLALIRLKPDQNGVSLGDKISPAKI-GTSNDLKDGDKLELIGY 161 >2SFA-A nrPDB Length = 191 Score = 33.2 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 12/31 (38%) Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRGPDFF 229 GD G L A G+ S G C G F Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGGTTF 175 >3LT3-A nrPDB Length = 217 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 52/179 (29%), Gaps = 29/179 (16%) Query: 54 GALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNL 113 G +I VMT A VV G+ ++ ++ S YDP Sbjct: 42 GFVISPDRVMTNAH-----------VVAGSNNVTVYAGDKPFEATVVS-----YDPSV-- 83 Query: 114 NDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT 173 D+ +L + + G V G+ + R + Sbjct: 84 -DVAILAVPHLPPPPLV-------FAAEPAKTGADVVVLGYPGGGNFTATPARIREA-IR 134 Query: 174 VTPEDQC-RPNNVCTGVLTRRGGICNGDGGTPLVC-EGLAHGVASFSLGPCGRGPDFFT 230 ++ D P V V T R + GD G PL+ G GV + T Sbjct: 135 LSGPDIYGDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGVVFGAAIDDAETGFVLT 193 >2SGA-A nrPDB Length = 181 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 12/31 (38%) Query: 199 GDGGTPLVCEGLAHGVASFSLGPCGRGPDFF 229 GD G L A G+ S G C G F Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGGTTF 165 >5OJX-A nrPDB Length = 254 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 13/42 (30%) Query: 122 DREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRL 163 A+L V G C V+G G RS L Sbjct: 206 SHPASLADYVKRSASSSTGQRFHDGLECMVSGMGQMRSQDSL 247 >4NWK-A nrPDB Length = 219 Score = 30.6 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 14/55 (25%) Query: 198 NGDGGTPLVCE-GLAHGVASFSLGPCGRGPDFFTRVALFRDWI-----DGVLNNP 246 G G PL+C G A G+ F C RG VA D+I + + +P Sbjct: 151 KGSSGGPLLCPAGHAVGI--FRAAVCTRG------VAKAVDFIPVESLETTMRSP 197 >5XIG-A nrPDB Length = 500 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 15/40 (37%), Gaps = 8/40 (20%) Query: 126 NLTSSVTILPLPLQNATVEAGTRCQVAG--------WGSQ 157 +T ++ L +P + GT+C G WG Sbjct: 460 VMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRS 499 >5XIP-A nrPDB Length = 498 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 127 LTSSVTILPLPLQNATVEAGTRCQVAG 153 +T ++ L +P + GTRC G Sbjct: 459 MTGAMKPLCIPFDQPPMPEGTRCFFTG 485 >4NCX-A nrPDB Length = 506 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 18/38 (47%) Query: 116 LMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAG 153 L L Q + E L+ ++ L +PL + +C +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >4FVB-A nrPDB Length = 152 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 7/20 (35%), Positives = 9/20 (45%) Query: 199 GDGGTPLVCEGLAHGVASFS 218 GD G L C+ G+ S Sbjct: 110 GDAGGILRCQHGVVGIVSTG 129 >3W95-A nrPDB Length = 171 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 7/20 (35%), Positives = 9/20 (45%) Query: 199 GDGGTPLVCEGLAHGVASFS 218 GD G L C+ G+ S Sbjct: 129 GDAGGILRCQHGVVGIVSTG 148 >4XZB-A nrPDB Length = 314 Score = 28.6 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 140 NATVEAGTRCQVAGWGSQRSGGRLSRFPRFVN 171 +A ++AGT V+ WG+ + G + Sbjct: 218 DAALQAGTPVFVSEWGTSDASGDGGPYLEEAE 249 >4NSY-A nrPDB Length = 275 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%), Gaps = 6/33 (18%) Query: 42 ASIQNQGRHFCGGALIHAR------FVMTAASC 68 A+ QG +C G+L++ + +TA C Sbjct: 26 AAYSKQGTMWCTGSLVNNSANDKKMYFLTANHC 58 >2HRV-A nrPDB Length = 142 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 12/27 (44%), Gaps = 1/27 (3%) Query: 193 RGGICN-GDGGTPLVCEGLAHGVASFS 218 G C GD G L+C+ G+ + Sbjct: 97 GEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >1HPG-A nrPDB Length = 187 Score = 28.2 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 14/37 (37%), Gaps = 2/37 (5%) Query: 193 RGGICN--GDGGTPLVCEGLAHGVASFSLGPCGRGPD 227 R C+ GD G +A G+ S S G G Sbjct: 133 RTTACSAGGDSGGAHFAGSVALGIHSGSSGCSGTAGS 169 >2M5T-A nrPDB Length = 142 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 17/44 (38%), Gaps = 5/44 (11%) Query: 193 RGGICN-GDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALF 235 G C GD G L+C G+ + G G FT + + Sbjct: 96 GEGPCVPGDAGGKLLCRHGVIGIITAG----GDGHVAFTDLRPY 135 >5ILB-A nrPDB Length = 474 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 44/137 (32%), Gaps = 36/137 (26%) Query: 31 RKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRR- 89 A P+ Q Q +I ++T A C +D + + Sbjct: 17 HTAPDYSLPWQK--QRQFTSTGSAFMIGDGKLLTNAHCV-------------EHDTQVKV 61 Query: 90 ERQSRQTFSISSMSENGYDPQQNLNDLML--------------LQLDREANLTSSVTILP 135 +R+ ++ + G D D+ L L+L L SVT++ Sbjct: 62 KRRGDDRKYVAKVLVRGVDC-----DIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVG 116 Query: 136 LPLQNATVEAGTRCQVA 152 PL T+ T+ V+ Sbjct: 117 YPLGGDTISV-TKGVVS 132 >4FLN-A nrPDB Length = 539 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 44/137 (32%), Gaps = 36/137 (26%) Query: 31 RKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRR- 89 A P+ Q Q +I ++T A C +D + + Sbjct: 57 HTAPDYSLPWQK--QRQFTSTGSAFMIGDGKLLTNAHCV-------------EHDTQVKV 101 Query: 90 ERQSRQTFSISSMSENGYDPQQNLNDLML--------------LQLDREANLTSSVTILP 135 +R+ ++ + G D D+ L L+L L SVT++ Sbjct: 102 KRRGDDRKYVAKVLVRGVDC-----DIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVG 156 Query: 136 LPLQNATVEAGTRCQVA 152 PL T+ T+ V+ Sbjct: 157 YPLGGDTISV-TKGVVS 172 >4B6E-A nrPDB Length = 683 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 23/55 (41%), Gaps = 14/55 (25%) Query: 198 NGDGGTPLVC-EGLAHGVASFSLGPCGRGPDFFTRVALFRDWI-----DGVLNNP 246 G G PL+C G A G+ F C RG VA D++ + + +P Sbjct: 171 KGSSGGPLLCPSGHAVGI--FRAAVCTRG------VAKAVDFVPVESMETTMRSP 217 >6FE6-A nrPDB Length = 165 Score = 26.7 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 14/29 (48%), Gaps = 3/29 (10%) Query: 198 NGDGGTPLVC-EGLAHGVASFSLGPCGRG 225 G G PL+C G A G+ F C RG Sbjct: 115 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 141 >5X88-A nrPDB Length = 199 Score = 26.7 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 10/22 (45%), Gaps = 5/22 (22%) Query: 46 NQGRHFCGGALIHARFVMTAAS 67 N G C G LI +TAA Sbjct: 164 NPGDLVCDGTLI-----LTAAH 180 >4U01-A nrPDB Length = 203 Score = 26.7 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 14/29 (48%), Gaps = 3/29 (10%) Query: 198 NGDGGTPLVC-EGLAHGVASFSLGPCGRG 225 G G PL+C G A G+ F C RG Sbjct: 137 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 163 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.159 0.579 Lambda K H 0.267 0.0484 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,434,713 Number of Sequences: 36641 Number of extensions: 501507 Number of successful extensions: 2473 Number of sequences better than 10.0: 196 Number of HSP's better than 10.0 without gapping: 305 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 991 Number of HSP's gapped (non-prelim): 369 length of query: 251 length of database: 10,336,785 effective HSP length: 95 effective length of query: 156 effective length of database: 6,855,890 effective search space: 1069518840 effective search space used: 1069518840 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.7 bits)