BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20151 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4NFE-A nrPDB 490 e-139 3QUM-P nrPDB 399 e-112 1SPJ-A nrPDB 326 5e-90 1GVZ-A nrPDB 296 8e-81 1SGF-G nrPDB 293 5e-80 1AO5-A nrPDB 283 4e-77 1SGF-A nrPDB 281 3e-76 1TON-A nrPDB 277 3e-75 1NPM-A nrPDB 216 1e-56 4WWY-A nrPDB 203 6e-53 1A0J-A nrPDB 203 8e-53 1F7Z-A nrPDB 202 1e-52 5MS3-A nrPDB 201 2e-52 5FXL-A nrPDB 199 1e-51 2PKA-B nrPDB 198 2e-51 5C67-A nrPDB 197 5e-51 4AN7-A nrPDB 197 5e-51 6QHB-A nrPDB 196 9e-51 2PSX-A nrPDB 193 6e-50 3BSQ-A nrPDB 190 4e-49 5ZFH-A nrPDB 186 6e-48 2TLD-E nrPDB 186 8e-48 2EEK-A nrPDB 185 2e-47 1UTJ-A nrPDB 184 5e-47 4E7N-A nrPDB 178 3e-45 2BDH-A nrPDB 175 1e-44 2AIQ-A nrPDB 174 4e-44 1FXY-A nrPDB 172 1e-43 4GSO-A nrPDB 167 4e-42 1OP0-A nrPDB 163 6e-41 3S69-A nrPDB 163 6e-41 5LPF-A nrPDB 157 5e-39 1BQY-A nrPDB 156 7e-39 3S9B-A nrPDB 156 1e-38 1FDP-A nrPDB 155 2e-38 1EUF-A nrPDB 152 2e-37 1NN6-A nrPDB 149 9e-37 5TJX-A nrPDB 146 9e-36 5XRF-A nrPDB 144 4e-35 1MZD-A nrPDB 143 7e-35 2CGA-A nrPDB 142 1e-34 6I44-A nrPDB 141 3e-34 3G01-A nrPDB 140 8e-34 5UGG-A nrPDB 139 1e-33 1FI8-A nrPDB 138 2e-33 1X7A-C nrPDB 137 4e-33 4MPW-A nrPDB 137 5e-33 4DUR-A nrPDB 136 1e-32 1ORF-A nrPDB 135 1e-32 3LC3-A nrPDB 135 1e-32 5FCR-A nrPDB 134 5e-32 2F83-A nrPDB 133 7e-32 3E0N-B nrPDB 132 2e-31 3T2N-A nrPDB 132 2e-31 3TK9-A nrPDB 131 2e-31 3DFJ-A nrPDB 131 2e-31 1AZZ-A nrPDB 131 3e-31 1LTO-A nrPDB 131 3e-31 1IAU-A nrPDB 130 5e-31 1P57-B nrPDB 130 8e-31 2RDL-A nrPDB 128 3e-30 6AOD-C nrPDB 127 4e-30 1SC8-U nrPDB 126 8e-30 1KYN-A nrPDB 125 2e-29 1FUJ-A nrPDB 124 4e-29 1YC0-A nrPDB 123 6e-29 5GVT-A nrPDB 122 1e-28 2V35-A nrPDB 122 2e-28 1BRU-P nrPDB 120 4e-28 2ZKS-A nrPDB 120 4e-28 2R0L-A nrPDB 120 6e-28 3RP2-A nrPDB 120 7e-28 5LHN-A nrPDB 119 2e-27 4Z6A-H nrPDB 119 2e-27 3F6U-H nrPDB 117 7e-27 2XRC-A nrPDB 116 1e-26 4DGJ-A nrPDB 116 1e-26 4Q7Y-A nrPDB 116 1e-26 2OQ5-A nrPDB 115 2e-26 2KAI-A nrPDB 114 5e-26 1EKB-B nrPDB 114 6e-26 5KWM-A nrPDB 113 1e-25 3P8G-A nrPDB 110 6e-25 5O32-I nrPDB 110 8e-25 4IGD-A nrPDB 109 1e-24 4XDE-A nrPDB 109 1e-24 3W94-A nrPDB 109 2e-24 2F91-A nrPDB 108 2e-24 4DJZ-B nrPDB 108 2e-24 1AE5-A nrPDB 108 2e-24 1AKS-B nrPDB 106 8e-24 1BDA-A nrPDB 106 9e-24 1MKW-K nrPDB 106 1e-23 2OCV-B nrPDB 106 1e-23 1A5I-A nrPDB 106 1e-23 1PYT-D nrPDB 105 2e-23 4H4F-A nrPDB 105 2e-23 1ELT-A nrPDB 105 3e-23 1FIZ-A nrPDB 103 6e-23 3NXP-A nrPDB 103 8e-23 1PQ7-A nrPDB 103 8e-23 3K65-B nrPDB 103 1e-22 4NZQ-A nrPDB 102 1e-22 1Q3X-A nrPDB 102 1e-22 1ETT-H nrPDB 102 2e-22 1FIW-A nrPDB 101 3e-22 1FON-A nrPDB 100 4e-22 1ZJK-A nrPDB 100 8e-22 4FXG-H nrPDB 100 9e-22 5XW8-A nrPDB 100 1e-21 1C5M-D nrPDB 99 2e-21 1KIG-H nrPDB 98 3e-21 1EQ9-A nrPDB 98 4e-21 4KKD-A nrPDB 97 6e-21 1PPF-E nrPDB 97 1e-20 4IW4-E nrPDB 96 1e-20 1VR1-H nrPDB 96 2e-20 2XXL-A nrPDB 96 2e-20 1SI5-H nrPDB 95 3e-20 1YM0-A nrPDB 95 3e-20 5TO3-B nrPDB 92 3e-19 2OLG-A nrPDB 88 3e-18 4LK4-A nrPDB 85 3e-17 5UBM-A nrPDB 85 3e-17 1ELV-A nrPDB 84 5e-17 4J1Y-A nrPDB 83 1e-16 2B9L-A nrPDB 82 2e-16 4BXW-A nrPDB 81 4e-16 6BQM-A nrPDB 81 6e-16 1MD7-A nrPDB 80 1e-15 4X0L-C nrPDB 79 1e-15 2QY0-B nrPDB 79 2e-15 4WJG-C nrPDB 79 3e-15 2ASU-B nrPDB 79 3e-15 1GPZ-A nrPDB 78 3e-15 2FMJ-A nrPDB 76 2e-14 3RU4-E nrPDB 75 3e-14 4F4O-C nrPDB 73 1e-13 2HLC-A nrPDB 72 2e-13 2JET-B nrPDB 72 2e-13 1M9U-A nrPDB 72 2e-13 3I77-A nrPDB 72 3e-13 3VGC-B nrPDB 70 7e-13 2JET-C nrPDB 70 8e-13 3H7O-A nrPDB 70 9e-13 3BEU-A nrPDB 70 1e-12 3H7T-A nrPDB 65 3e-11 1RIW-B nrPDB 59 2e-09 1BBR-E nrPDB 58 3e-09 2I6S-A nrPDB 57 7e-09 1BBR-H nrPDB 57 8e-09 2HNT-F nrPDB 55 2e-08 2WIN-I nrPDB 53 1e-07 2OK5-A nrPDB 53 2e-07 1DLE-A nrPDB 53 2e-07 1EPT-B nrPDB 52 2e-07 2HNT-C nrPDB 39 0.002 3F1S-B nrPDB 36 0.018 3H5C-B nrPDB 34 0.079 6BPF-A nrPDB 32 0.28 1G0D-A nrPDB 31 0.56 1P3E-A nrPDB 29 2.1 5VC2-A nrPDB 29 2.6 5KMU-A nrPDB 28 4.8 3LCV-B nrPDB 28 5.2 3ARQ-A nrPDB 28 5.8 2PFE-A nrPDB 27 9.2 >4NFE-A nrPDB Length = 237 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 237 >3QUM-P nrPDB Length = 237 Score = 399 bits (1024), Expect = e-112, Method: Compositional matrix adjust. Identities = 188/237 (79%), Positives = 210/237 (88%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECEKHSQPWQV V S G A CGGVLVHPQWVLTAAHC++ S + LGRH+LF PE Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHDLMLLRLSEPA++TD VKV+ LPTQ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EPALGTTCYASGWGSIEPEEFL P+ LQCV LH++SND+CA+ + +KVT+FMLCAG WTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P++YTKVVHYRKWIKDTI ANP Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 237 >1SPJ-A nrPDB Length = 238 Score = 326 bits (836), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 155/237 (65%), Positives = 184/237 (77%), Gaps = 1/237 (0%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECE+HSQPWQ A+Y CGG+LVH QWVLTAAHC+ N Q+WLGRHNLF+ E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK-ITDVVKVLGLPT 143 +T Q V VS SFPHP +NMSLL++ + + DED SHDLMLLRL+EPA ITD VKV+ LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 +EP +G+TC ASGWGSIEPE F P LQCV L +L ND C +A+ +KVT+FMLC G Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTC GDSGGPL+C+GVLQG+TSWG PC P KP+V +V+ Y KWI+DTIA N Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >1GVZ-A nrPDB Length = 237 Score = 296 bits (757), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 144/236 (61%), Positives = 171/236 (72%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GGWECEKHS+PWQVAVY G CGGVLVHPQWVLTAAHC+ + Q+WLGRHNL + E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DT Q VS SF P +++SLLK + LRP +D SHDLMLLRL++PA+ITD VK+L LPTQ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP LG+TCY SGWG I +LQCV L L SN+ CARAY EK+TEF+LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 C GDSGG L+C+GV QGITSWG CA V+TKV+ ++KWIK+TI N Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1SGF-G nrPDB Length = 237 Score = 293 bits (750), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 142/237 (59%), Positives = 174/237 (73%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG++CEK+SQPW VAVY + CGGVL+ P WVLTAAHC N +VWLG++NLF+ E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q VS + PHP +NMSL++ + D S+DLMLLRLS+PA ITD VK + LPT+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP LG+TC ASGWGSI P +F L CV+L LL N+ CA+A+ EKVT+ MLCAG G Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTC GDSGGPL+C+GVLQGITSWG PC P+ P VYTK+ + WIKDT+A NP Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKNP 237 >1AO5-A nrPDB Length = 237 Score = 283 bits (725), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 136/236 (57%), Positives = 168/236 (71%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG+ CEK+SQPWQVAVY CGGVL+ WVLTAAHC +VWLG++ LF+ E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q VS SFPHP +NMSLL Q++ P D S DLMLLRLS+PA ITDVVK + LPT+ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP G+ C ASGWGSI P + +P LQCV + LL N+ CA+ Y +KVT+ MLCAG G Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKDTC DSGGPL+C+G+LQG TS+GP PC P PA+YT ++ + WIKDT+ N Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >1SGF-A nrPDB Length = 240 Score = 281 bits (718), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 137/245 (55%), Positives = 174/245 (71%), Gaps = 5/245 (2%) Query: 17 AVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLG 76 A P +QS++ +CE +SQPW VAVY CGGVL+ WVLTAAHC QVWLG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 ++N E E + Q VS + PHP +NMSLL + +P++D S+DLMLLRLS+PA ITDVV Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 K + LPT+EP LG+TC ASGWGS P +F P LQCV+L LL N+ C +A+ KVT+ M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 LCAG GG TC DSGGPL+C+G+LQGITSWGPEPC P +P+VYTK++ + WI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 IAANP 261 +A NP Sbjct: 236 MANNP 240 >1TON-A nrPDB Length = 235 Score = 277 bits (709), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 134/237 (56%), Positives = 166/237 (70%), Gaps = 2/237 (0%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG++CEK+SQPWQVAV + CGGVL+ P WV+TAAHC N QV LGR+NLF+ E Sbjct: 1 IVGGYKCEKNSQPWQVAVINEYL--CGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 QR V SF HP Y ++ + + +P D S+DLMLL LSEPA IT VKV+ LPT+ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP +G+TC ASGWGS P E + LQCV++HLLSN+ C Y + VT+ MLCAG G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTC GDSGGPL+C+GVLQGITS G PCA P+ PA+Y K++ + WIK + NP Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP 235 >1NPM-A nrPDB Length = 225 Score = 216 bits (549), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 112/233 (48%), Positives = 141/233 (60%), Gaps = 9/233 (3%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G EC HSQPWQ A++ CGGVLV +WVLTAAHC K+ V LG H+L + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + V+ S HP YN S ED SHD+ML+RL A + D VK + L Sbjct: 61 QPEQEIQVAQSIQHPCYNNS--------NPEDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 P +G C SGWG++ + P +L C + + S + C RAY K+TE M+CAG + Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SN 171 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G DTC GDSGGPLVC+G+LQGITSWG +PC PEKP VYTK+ Y WIK T+ Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >4WWY-A nrPDB Length = 224 Score = 203 bits (517), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 107/236 (45%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ CE++S P+QV++ S G+ CGG L++ QWV++A HC K QV LG HN+ E Sbjct: 1 IVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + + HP Y+ L ++D+ML++LS A I V + LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 PA GT C SGWG+ P LQC+ +LS C +Y K+T M C G G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C DSGGP+VCNG LQG+ SWG + CA KP VYTKV +Y KWIK+TIAAN Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1A0J-A nrPDB Length = 223 Score = 203 bits (516), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 103/236 (43%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+EC K+S +Q ++ S G+ CGG L+ WV++AAHC K QV LG HN+ E Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 T Q + HP YN L + D+ML++LS+PA + V + LP+ Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNLDN-----------DIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 + GT C SGWG++ P +L+C+ L +LS+ C AY ++T M CAG G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C GDSGGP+VCNG LQG+ SWG CA KP VYTKV +YR WI T+++N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1F7Z-A nrPDB Length = 233 Score = 202 bits (513), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 106/236 (44%), Positives = 141/236 (59%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ C+++S P+QV++ S G+ CGG L++ QWV++AAHC K QV LG HN+ E Sbjct: 11 IVGGYTCQENSVPYQVSLNS-GYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q V + HP ++ L ++D+ML++LS P K+ V + LP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTL-----------NNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GT C SGWG+ P LQC+ LL C +Y K+T+ M+C G G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C GDSGGP+VCNG LQGI SWG CALP+ P VYTKV +Y WI+DTIAAN Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >5MS3-A nrPDB Length = 228 Score = 201 bits (511), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 105/236 (44%), Positives = 134/236 (56%), Gaps = 9/236 (3%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 ++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 G C SGWG++ P +L C + + C AY ++T+ M+CAG + Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SK 171 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I + Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >5FXL-A nrPDB Length = 246 Score = 199 bits (506), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 103/237 (43%), Positives = 139/237 (58%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+ C ++ P+QV++ S G+ CGG L++ QWV++AAHC K QV LG N+ Sbjct: 23 KIVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVV 81 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q + S S HP YN + L ++D+ML++L A + V + LPT Sbjct: 82 EGNEQFISASKSIVHPSYNSNTL-----------NNDIMLIKLKSAASLNSRVASISLPT 130 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 + GT C SGWG+ + P L+C+ +LS+ C AY ++T M CAG Sbjct: 131 SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLE 190 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VC+G LQGI SWG CA KP VYTKV +Y WIK TIA+N Sbjct: 191 GGKDSCQGDSGGPVVCSGKLQGIVSWG-SGCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >2PKA-B nrPDB Length = 152 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 98/149 (65%), Positives = 111/149 (74%), Gaps = 2/149 (1%) Query: 115 EDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEP--EEFLRPRSLQ 172 +D SHDLMLLRL PAKITD VKVL LPTQEP LG+TC ASGWGSIEP ++F P +Q Sbjct: 4 KDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEIQ 63 Query: 173 CVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPE 232 CV L LL N CA A+ +KVTE MLCAG GGKDTC GDSGGPL+CNG+ QGITSWG Sbjct: 64 CVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHT 123 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTIAANP 261 PC KP++YTK++ Y WI DTI NP Sbjct: 124 PCGSANKPSIYTKLIFYLDWIDDTITENP 152 >5C67-A nrPDB Length = 224 Score = 197 bits (500), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 106/236 (44%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K QV LG HN+ E Sbjct: 1 IVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + + HP YN L +D+ML++LS PA I V + LPT Sbjct: 60 GNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 PA GT C SGWG+ P L+C+ +L+ C +Y K+T M C G G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C D+GGP+VCNG LQG+ SWG CA +P VYTKV +Y WIKDTIAAN Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >4AN7-A nrPDB Length = 231 Score = 197 bits (500), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 104/237 (43%), Positives = 138/237 (58%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+ C +S P+QV++ S G CGG L++ QWV++AAHC K QV LG HN+ Sbjct: 8 KIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q + + HP +N + L + D+ML++LS PA + V + LP Sbjct: 67 EGNEQFINAAKIITHPNFNGNTLDN-----------DIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 A GT C SGWG+ + P LQC+ +LS+ C +Y ++T M+C G Sbjct: 116 SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLE 175 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VCNG LQGI SWG CA KP VYTKV +Y WI+ TIAAN Sbjct: 176 GGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >6QHB-A nrPDB Length = 223 Score = 196 bits (498), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 105/236 (44%), Positives = 143/236 (60%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +V G C+K S P+Q A+Y+ G CGGVL+HP WVLTAAHC K N QV+LG+HNL + E Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + ++ V + HP Y+ + D+MLLRL+ PAK++++++ L L Sbjct: 61 SSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLERD 109 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 A T+C+ GWG +F P ++QC +HL+S + C AY ++T+ MLCAG Sbjct: 110 CSAQTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKY 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C GDSGGPLVC L+G+ SWG PC EKP VYT V Y WI+ TI A Sbjct: 168 GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >2PSX-A nrPDB Length = 227 Score = 193 bits (491), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 100/238 (42%), Positives = 145/238 (60%), Gaps = 14/238 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 I+ G +C+ H+QPWQ A+ +CG VLVHPQW+LTAAHC KK +V LG ++L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 84 EDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 ++GQ++ S PHP Y+ S+DLML++L+ + T V+ + + Sbjct: 61 YESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 + P+ GT C SGWG+ + + P+ LQC+++ +LS C AY ++ + M CAG Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD- 168 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G+D+C GDSGGP+VCNG LQG+ SWG PCA P +P VYT + + KWI++TI AN Sbjct: 169 KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3BSQ-A nrPDB Length = 227 Score = 190 bits (483), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 99/233 (42%), Positives = 132/233 (56%), Gaps = 13/233 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G C + S PWQVA+ S HCGGVLV+ +WVLTAAHC V LG L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 QR+ S SF HP Y+ + +DLML++L+ A+++ +VK + LP++ Sbjct: 61 --AQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GTTC SGWG+ + P L CV + L+S C + Y + + MLCAG+ Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 K+ C GDSGGPLVC G LQG+ SWG PC P P VYT+V + KWI DT+ Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 220 >5ZFH-A nrPDB Length = 224 Score = 186 bits (473), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 93/236 (39%), Positives = 134/236 (56%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G++C++ S PWQVA+ HCGGVLV WVLTAAHC QV LG + + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGD-- 58 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q++ + SF HP Y+ + +D+ML+RL EP K++ V+ + LP Sbjct: 59 QSAQKIKATKSFRHPGYST-----------KTHVNDIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GT+C SGWG+ + P L C + L+S+ C + Y + + + MLCAG+ Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 +TC GDSGGPLVCN LQG+ SWG PC P P VYT+V Y++W+ +T+ + Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >2TLD-E nrPDB Length = 220 Score = 186 bits (472), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 102/236 (43%), Positives = 136/236 (57%), Gaps = 16/236 (6%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ C ++ P+QV++ S G+ CGG L++ QWV++AAHC K QV LG N+ E Sbjct: 1 IVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + S S HP YN + L + D+ML++L A + V + LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTLNN-----------DIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 + GT C SGWG+ + P L+C+ +LS+ C AY ++T M CAGL Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE-- 166 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G D+C GDSGGP+VC+G LQGI SWG CA KP VYTKV +Y WIK TIA+N Sbjct: 167 GGDSCQGDSGGPVVCSGKLQGIVSWG-SGCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >2EEK-A nrPDB Length = 220 Score = 185 bits (469), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 102/234 (43%), Positives = 138/234 (58%), Gaps = 14/234 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+EC KHSQ QV++ S G+ CGG LV WV++AAHC K +V LG H++ E Sbjct: 1 IVGGYECTKHSQAHQVSLNS-GYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 T Q + S HP Y+ + ++D+ML++L++PA + V + LPT+ Sbjct: 60 GTEQYISSSSVIRHPNYS-----------SYNINNDIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 A T C SGWG+ LQC+SL +LS+ CA +Y +T+ M CAG G Sbjct: 109 CAADATMCTVSGWGNTM-SSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 GKD+C GDSGGP+VCNGVLQG+ SWG CA + P VY KV W++DT+A Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTMA 220 >1UTJ-A nrPDB Length = 242 Score = 184 bits (466), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 98/236 (41%), Positives = 136/236 (57%), Gaps = 14/236 (5%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+EC+ +SQP QV++ S G+ CGG LV+ WV++AAHC K +V LG HN+ Sbjct: 20 KIVGGYECKPYSQPHQVSLNS-GYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVT 78 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E + Q + S HP Y+ + +D+ML++LS+PA + V+ + LPT Sbjct: 79 EGSEQFISSSRVIRHPNYS-----------SYNIDNDIMLIKLSKPATLNTYVQPVALPT 127 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 GT C SGWG+ LQC+++ +LS C +Y +T M CAG Sbjct: 128 SCAPAGTMCTVSGWGNTMSST-ADSNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYLE 186 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 GGKD+C GDSGGP+VCNG LQG+ SWG CA P P VY KV + W+ T+A+ Sbjct: 187 GGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFNDWLTSTMAS 241 >4E7N-A nrPDB Length = 238 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 104/242 (42%), Positives = 135/242 (55%), Gaps = 17/242 (7%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 I+GG EC + + VA+Y+ CGG L++ +WVLTAAHC +KN ++ LG H+ Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 P-EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 P ED RVP F N +L D+ML+RL P K + + L Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTLW-----------DKDIMLIRLDSPVKNSKHIAPFSL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE---KVTEFMLC 198 P+ P++G+ C GWG I P E P CV+++LL +MC Y E T LC Sbjct: 110 PSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLC 169 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 AG+ GGKDTC GDSGGPL+CNG QGI SWG +PCA P KPA YTKV + WI++ IA Sbjct: 170 AGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIA 229 Query: 259 AN 260 N Sbjct: 230 GN 231 >2BDH-A nrPDB Length = 223 Score = 175 bits (444), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 95/236 (40%), Positives = 134/236 (56%), Gaps = 14/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 85 DTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 + G Q V S S HP YN LL ++DLML++L E +D ++ + + + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >2AIQ-A nrPDB Length = 231 Score = 174 bits (441), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 92/237 (38%), Positives = 132/237 (55%), Gaps = 14/237 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 83 ++GG EC + + VY++G + CGG L++ +WVLTA HC + N +++LG HNL Sbjct: 1 VIGGDECNINEHRFLALVYANG-SLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 +D +R P F + R D D+ML+RL+ P + + + L LP+ Sbjct: 60 KDALRRFPKEKYF-----------CLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPS 108 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 P++G+ C GWG+I P C ++++L +C AY + + LCAG+ Sbjct: 109 NPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAY-KGLAATTLCAGILE 167 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTC GDSGGPL+CNG QGI S G PCA P KP +YTKV Y WI+ I+ N Sbjct: 168 GGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >1FXY-A nrPDB Length = 228 Score = 172 bits (437), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 101/239 (42%), Positives = 129/239 (53%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQ-VAVYSHGWAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLF 81 IVGG+ C+ PWQ + + CGG ++ ++LTAAHCL K +V +G N Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNT- 59 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E+ G+ V H + ++KH E D+ +LRL P V L Sbjct: 60 EQEEGGEAV-------HEV--EVVIKHNRFT-KETYDFDIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 PT PA GT C SGWG+ P LQC+ +LS C +Y K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VCNG LQG+ SWG + CA KP VYTKV +Y KWIK+TIAAN Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >4GSO-A nrPDB Length = 232 Score = 167 bits (423), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 93/237 (39%), Positives = 129/237 (54%), Gaps = 13/237 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 83 ++GG EC+ + P+ +YSHG+ CG L++ +WV+TAAHC N Q+ LG H+ Sbjct: 1 VLGGDECDINEHPFLAFLYSHGY-FCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 ED R P F P NMS E D+ML++L +P + + L LP+ Sbjct: 60 EDEQTRNP-KEKFICPNKNMS----------EVLDKDIMLIKLDKPISNSKHIAPLSLPS 108 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 P++G+ C GWGSI P C +++L+ ++C AY+ + LCAG+ Sbjct: 109 NPPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLE 168 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTC GDSGGPL+CNG QGI S+G C KP +YT V Y WI+ IA N Sbjct: 169 GGKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >1OP0-A nrPDB Length = 234 Score = 163 bits (413), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 92/242 (38%), Positives = 136/242 (56%), Gaps = 21/242 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 83 ++GG EC+ + + VA ++ CGG L++P+WV+TAAHC + Q+ LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH----DLMLLRLSEPAKITDVVKVL 139 ED R P K + + P+++++ D+ML++L +P + + L Sbjct: 61 EDEQTRNP---------------KEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPL 105 Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF-MLC 198 LP+ P++G+ C GWGSI P + P C +++LL + +C Y E + E+ LC Sbjct: 106 SLPSSPPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLC 165 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 AG+ GGKDTCGGDSGGPL+CNG QGI S+G PC KP +YT V Y WI+ IA Sbjct: 166 AGIVQGGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIA 225 Query: 259 AN 260 N Sbjct: 226 GN 227 >3S69-A nrPDB Length = 234 Score = 163 bits (413), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 96/238 (40%), Positives = 130/238 (54%), Gaps = 13/238 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 83 ++GG EC + VA ++ C G L++ +WVLTAAHC N Q+ LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 ED R P F P + + DE D+ML++L ++ + L LP+ Sbjct: 61 EDEQTRNP-KEKFICP----------NKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF-MLCAGLW 202 P++G+ C+ GWGSI P + P C ++LL + +C Y E +TE+ LCAG+ Sbjct: 110 SPPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGIL 169 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTCGGDSGGPL+CNG QGI S+G PC KP VYTKV Y WI+ IA N Sbjct: 170 EGGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >5LPF-A nrPDB Length = 234 Score = 157 bits (396), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 94/233 (40%), Positives = 121/233 (51%), Gaps = 5/233 (2%) Query: 28 GWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTG 87 G C + SQPWQV++++ HC GVLV WVLTAAHC K +G +L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ 66 Query: 88 QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA 147 R + S HP Y+ R DE HDLMLL+L+ P + V+ L LP + Sbjct: 67 LRR-TTRSVVHPKYHQGSGPILPRRTDE---HDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKD 207 G C +GWG+ + L C S+ +LS C Y VT M+CAGL G+D Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQD 181 Query: 208 TCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 C DSGGPLVC+ LQGI SWG PC + PAVYT++ Y WI I +N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >1BQY-A nrPDB Length = 234 Score = 156 bits (395), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 88/238 (36%), Positives = 126/238 (52%), Gaps = 13/238 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 83 + GG EC + V +++ CGG L++ WV+TAAHC N Q+ G H+ Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 ED R P F + + D++ D+ML++L ++ + L LP+ Sbjct: 61 EDEQTRDPKEKFFC-----------PNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKVTEFMLCAGLW 202 P++G+ C GWG P + + P C ++++L + +C AYS +V LCAG+ Sbjct: 110 SPPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGIL 169 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GG+DTC DSGGPL+CNG+ QGI SWG PC P +P VYTKV Y WIK IA N Sbjct: 170 QGGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >3S9B-A nrPDB Length = 234 Score = 156 bits (394), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 90/246 (36%), Positives = 128/246 (52%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-F 81 +VGG EC + P+ VA+Y+ + HC G L++ +WVLTAAHC ++N ++ LG H+ Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 82 EPEDTGQRVP------VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 ED RVP ++ FP+ L D+ML+RL P + Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNGL-----------------DKDIMLIRLRRPVTYSTH 103 Query: 136 VKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKVTE 194 + + LP++ +G+ C GWG I + P C ++ ++ + C Y Sbjct: 104 IAPVSLPSRSRGVGSRCRIMGWGKISTTTY--PDVPHCTNIFIVKHKWCEPLYPWVPADS 161 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254 LCAG+ GG+DTC GDSGGPL+CNG + GI + G EPC KPAVYTKV Y WI+ Sbjct: 162 RTLCAGILKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQ 221 Query: 255 DTIAAN 260 IA N Sbjct: 222 SIIAGN 227 >1FDP-A nrPDB Length = 235 Score = 155 bits (392), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 97/245 (39%), Positives = 136/245 (55%), Gaps = 22/245 (8%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS----QVWLGR 77 + RI+GG E E H++P+ +V +G CGGVLV QWVL+AAHCL+ + QV LG Sbjct: 5 RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGA 64 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 H+L +PE + + V + PHP +PD HDL+LL+LSE A + V+ Sbjct: 65 HSLSQPEPSKRLYDVLRAVPHP----------DSQPDT-IDHDLLLLQLSEKATLGPAVR 113 Query: 138 VL--GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVT 193 L ++ A GT C +GWG + RP SLQ V L +L C R + +T Sbjct: 114 PLPWQRVDRDVAPGTLCDVAGWGIVN-HAGRRPDSLQHVLLPVLDRATCNRRTHHDGAIT 172 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 E ++CA + +D+C GDSGGPLVC GVL+G+ + G C +KP +YT+V Y WI Sbjct: 173 ERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 230 Query: 254 KDTIA 258 +A Sbjct: 231 DSVLA 235 >1EUF-A nrPDB Length = 227 Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 92/238 (38%), Positives = 125/238 (52%), Gaps = 20/238 (8%) Query: 25 IVGGWECEKHSQPWQVAVY--SHGWAH-CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ + + G +H CGG LV +VLTAAHCL + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN DE ++D+MLL+L+ A ITD V + L Sbjct: 61 ERERTQQVIPVRRPIPHPDYN-----------DETLANDIMLLKLTRKADITDKVSPINL 109 Query: 142 PTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 P E G C +GWG + LQ V L + S + C + + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRLG-VNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G + K++ GDSGGPLVCNGV QGI S+G P+ VYT++ + WI T+ Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRNDGTTPD---VYTRISSFLSWIHSTM 223 >1NN6-A nrPDB Length = 228 Score = 149 bits (377), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 128/244 (52%), Gaps = 26/244 (10%) Query: 25 IVGGWECEKHSQPWQV---AVYSHGWAH-CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG EC+ HS+P+ V S+G + CGG L+ +VLTAAHC ++ V LG HN+ Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 62 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E EDT Q++ V F HP YN S L HD+MLL+L E A +T V L Sbjct: 63 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 111 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRS--LQCVSLHLLSNDMCARAYSEKVTEFM 196 P+Q + G C +GWG L+P S LQ V L L+ C+ + + Sbjct: 112 FPSQFNFVPPGRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQ 167 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 LC G K GDSGGPL+C GV QGI S+G + PAV+T++ HYR WI Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQI 224 Query: 257 IAAN 260 + AN Sbjct: 225 LQAN 228 >5TJX-A nrPDB Length = 263 Score = 146 bits (369), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 97/243 (39%), Positives = 132/243 (54%), Gaps = 22/243 (9%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLKKN--SQVWLGR 77 +RIVGG E PWQV++ A CGG L+ QWVLTAAHC VW Sbjct: 14 TRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 + E D + P S ++ HQ+ + E +HD+ L++L P + T+ K Sbjct: 74 SGILELSDITKDTPFSQI-------KEIIIHQNYKVSE-GNHDIALIKLQAPLEYTEFQK 125 Query: 138 VLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVTE 194 + LP++ + T C+ +GWG E+ LQ V++ L++N+ C + Y + K+T+ Sbjct: 126 PISLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 184 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTKVVHYR 250 M+CAG GGKD C GDSGGPLVC NG+ L GITSWG E CA E+P VYTKV Y Sbjct: 185 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYM 243 Query: 251 KWI 253 WI Sbjct: 244 DWI 246 >5XRF-A nrPDB Length = 242 Score = 144 bits (363), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 85/241 (35%), Positives = 128/241 (53%), Gaps = 19/241 (7%) Query: 25 IVGGWECEKHSQPWQVAVY-SHGWA-HCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 ++GG EC+ + + A + S W C G L+H +WVL AAHC K+ ++LG HN Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH---DLMLLRLSEPAKITDVVKVL 139 D QR ++ R DE + D++LL+L++P + + L Sbjct: 67 QFDDEQR-------------RYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPL 113 Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVTEFMLC 198 LP+ P++G+ C GWG + + + P C +++LL+ C Y + T +LC Sbjct: 114 SLPSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLC 173 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 AG+ GG DTC DSGGPL+C+G QGI +G PCA P KP +YT+V +Y WI++ IA Sbjct: 174 AGVLEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIA 233 Query: 259 A 259 Sbjct: 234 G 234 >1MZD-A nrPDB Length = 240 Score = 143 bits (361), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 86/244 (35%), Positives = 134/244 (54%), Gaps = 23/244 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ-----VWLGRHN 79 I+GG E HS+P+ ++ G CGGVL+ PQWVLTAAHC + ++ V LG H+ Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + E + Q + + P S + S+D+ML++L AK+ VK+L Sbjct: 63 LSKNEASKQTLEIKKFIPF-----------SRVTSDPQSNDIMLVKLQTAAKLNKHVKML 111 Query: 140 GLPTQEPAL-GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC-ARAYSEK---VTE 194 + ++ GT C +GWG+ +P+ +L+ V++ +LS +C +++Y +T+ Sbjct: 112 HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 171 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVV-HYRKWI 253 M+CAG G KD+C GD+GGPL+C GV I S G E C + KP +YT + Y+ WI Sbjct: 172 DMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWI 230 Query: 254 KDTI 257 K + Sbjct: 231 KSNL 234 >2CGA-A nrPDB Length = 245 Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 95/257 (36%), Positives = 130/257 (50%), Gaps = 28/257 (10%) Query: 18 VPLIQ------SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKN 70 VP IQ SRIV G E S PWQV++ G+ CGG L++ WV+TAAHC Sbjct: 3 VPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTT 62 Query: 71 SQVWL-GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP 129 S V + G + + Q++ ++ F + YN + ++D+ LL+LS Sbjct: 63 SDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTI-----------NNDITLLKLSTA 111 Query: 130 AKITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA 187 A + V + LP+ + A GTTC +GWG P LQ SL LLSN C + Sbjct: 112 ASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKY 171 Query: 188 YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NG--VLQGITSWGPEPCALPEKPAVY 243 + K+ + M+CAG G +C GDSGGPLVC NG L GI SWG C+ P VY Sbjct: 172 WGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCS-TSTPGVY 228 Query: 244 TKVVHYRKWIKDTIAAN 260 +V W++ T+AAN Sbjct: 229 ARVTALVNWVQQTLAAN 245 >6I44-A nrPDB Length = 627 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 96/244 (39%), Positives = 133/244 (54%), Gaps = 24/244 (9%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLKKN--SQVWLGR 77 +RIVGG + PWQV++ A CGG L+ QWVLTAAHC VW Sbjct: 378 TRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 437 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 + + D + P S ++ HQ+ + E +HD+ L++L P + T+ K Sbjct: 438 SGILQLSDITKDTPFSQI-------KEIIIHQNYKVSE-GNHDIALIKLQAPLQYTEFQK 489 Query: 138 VLGLPTQ--EPALGTTCYASGWG-SIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVT 193 + LP++ + T C+ +GWG S E E LQ V++ L++N+ C + Y + K+T Sbjct: 490 PICLPSKGDTSTIYTNCWVTGWGFSAEAGEI--QNILQKVNIPLVTNEECQKRYQDYKIT 547 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTKVVHY 249 + M+CAG GGKD C GD+GGPLVC NG+ L GITSWG E CA E+P VYTKV Y Sbjct: 548 QRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEY 606 Query: 250 RKWI 253 WI Sbjct: 607 MDWI 610 >3G01-A nrPDB Length = 227 Score = 140 bits (352), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 127/242 (52%), Gaps = 26/242 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSH-----GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHN 79 I+GG E HS+P+ +A Y CGG LV ++VLTAAHC ++ V LG HN Sbjct: 1 IIGGNEISPHSRPY-MAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHN 59 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 + E+T Q +PV+ + PHP YN PD D S+D+MLL+L AK T V+ L Sbjct: 60 IKAKEETQQIIPVAKAIPHPDYN----------PD-DRSNDIMLLKLVRNAKRTRAVRPL 108 Query: 140 GLPTQEPAL--GTTCYASGWGSIEPE-EFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 LP + + G CY +GWG + P+ EF P++L V L + + +C + Sbjct: 109 NLPRRNAHVKPGDECYVAGWGKVTPDGEF--PKTLHEVKLTVQKDQVCESQFQSSYNRAN 166 Query: 197 -LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 +C G + GDSGGPLVC GI S+G + P+ V+T+V+ + WIK Sbjct: 167 EICVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQTDGSAPQ---VFTRVLSFVSWIKK 223 Query: 256 TI 257 T+ Sbjct: 224 TM 225 >5UGG-A nrPDB Length = 251 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 96/251 (38%), Positives = 127/251 (50%), Gaps = 34/251 (13%) Query: 24 RIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNS-----QVWLGR 77 R+VGG HS PWQV++ + G CGG L+ P+WVLTAAHCL+K+ +V LG Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 H E Q + VS F P + D+ LL+LS PA ITD V Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 123 Query: 138 VLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYSEKVT 193 LP+ + T C+ +GWG E + L+ L ++ N +C R + +V Sbjct: 124 PACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQ 181 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHY 249 LCAG GG D+C GDSGGPLVC +LQG+TSWG CA P KP VY +V + Sbjct: 182 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRF 240 Query: 250 RKWIKDTIAAN 260 WI+ + N Sbjct: 241 VTWIEGVMRNN 251 >1FI8-A nrPDB Length = 228 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 120/242 (49%), Gaps = 26/242 (10%) Query: 25 IVGGWECEKHSQPW----QVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG E + HS+P+ Q+ G CGG L+ +VLTAAHC QV LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E E Q +PV PHP YN + S+D+MLL+L AK + VK L Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA---RAYSEKVTEF 195 LP + + G CY +GWG + P +LQ V L + + C + Y +K E Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGPMGKYSD-TLQEVELTVQEDQKCESYLKNYFDKANE- 167 Query: 196 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 +CAG + + GDSGGPLVC V GI S+G + P +TKV + WIK Sbjct: 168 -ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKK 223 Query: 256 TI 257 T+ Sbjct: 224 TM 225 >1X7A-C nrPDB Length = 235 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 91/245 (37%), Positives = 124/245 (50%), Gaps = 29/245 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL--GRHNLFE 82 IVGG + PWQV + A CGG +++ +WV+TAAHC++ ++ + G +N E Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T QR V + PH YN ++ K+ SHD+ LL L EP + V + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKY---------SHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLRPRS---LQCVSLHLLSNDMCARAYSEKVTE 194 +E G+ Y SGWG + F R RS LQ + + L+ C R+ + Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRV----FNRGRSATILQYLKVPLVDRATCLRSTKFTIYS 166 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 M CAG GGKD+C GDSGGP V L GI SWG E CA+ K +YTKV Y Sbjct: 167 NMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWG-EECAVKGKYGIYTKVSRYV 225 Query: 251 KWIKD 255 WIK+ Sbjct: 226 NWIKE 230 >4MPW-A nrPDB Length = 245 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 95/262 (36%), Positives = 133/262 (50%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHG--WAH-CGGVLVHPQWVLTAAHCLKKNSQ------VWL 75 IVGG E + PWQV++ HG W H CGG L+HPQWVLTAAHC+ + + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 +L+ + Q +PVS HP + + + D+ LL L EP K++ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVKVSSH 106 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFL-RPRSLQCVSLHLLSNDMCARAYS--- 189 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 107 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NG--VLQGITSWGPEPCALPEK 239 V + MLCAG +D+C GDSGGPLVC NG + G+ SWG E CA P + Sbjct: 167 YTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 223 Query: 240 PAVYTKVVHYRKWIKDTIAANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >4DUR-A nrPDB Length = 791 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 96/251 (38%), Positives = 127/251 (50%), Gaps = 34/251 (13%) Query: 24 RIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNS-----QVWLGR 77 R+VGG HS PWQV++ + G CGG L+ P+WVLTAAHCL+K+ +V LG Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 H E Q + VS F P + D+ LL+LS PA ITD V Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 663 Query: 138 VLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVT 193 LP+ + T C+ +GWG E + L+ L ++ N +C R + +V Sbjct: 664 PACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQ 721 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHY 249 LCAG GG D+C GDSGGPLVC +LQG+TSWG CA P KP VY +V + Sbjct: 722 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRF 780 Query: 250 RKWIKDTIAAN 260 WI+ + N Sbjct: 781 VTWIEGVMRNN 791 >1ORF-A nrPDB Length = 234 Score = 135 bits (341), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 122/242 (50%), Gaps = 21/242 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFEP 83 I+GG E HS+P+ V + C G L+ WVLTAAHC L K SQV LG H++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E T Q + V FP+P Y+ + DL LL+L+E AKI V +L LP Sbjct: 61 EPTKQIMLVKKEFPYPCYDPAT-----------REGDLKLLQLTEKAKINKYVTILHLPK 109 Query: 144 QEPAL--GTTCYASGWGSIEPE----EFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 197 + + GT C +GWG + LR + + + ND ++ + M+ Sbjct: 110 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVEITIID-RKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPE-PCALPEKPAVYTKVV-HYRKWIKD 255 CAG GG+D+C GDSG PL+C GV +G+TS+G E C P P VY + + WI Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 228 Query: 256 TI 257 TI Sbjct: 229 TI 230 >3LC3-A nrPDB Length = 235 Score = 135 bits (341), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 125/245 (51%), Gaps = 29/245 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL--GRHNLFE 82 +VGG + + PWQV + A CGG +V+ +W++TAAHC++ ++ + G HN+ E Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T Q+ V PH YN ++ K+ +HD+ LL L EP + V + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINKY---------NHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLRPRS---LQCVSLHLLSNDMCARAYSEKVTE 194 +E G+ Y SGWG + F + RS LQ + + L+ C R+ + Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRV----FHKGRSALVLQYLRVPLVDRATCLRSTKFTIYN 166 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 M CAG GG+D+C GDSGGP V L GI SWG E CA+ K +YTKV Y Sbjct: 167 NMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWG-EECAMKGKYGIYTKVSRYV 225 Query: 251 KWIKD 255 WIK+ Sbjct: 226 NWIKE 230 >5FCR-A nrPDB Length = 234 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 127/247 (51%), Gaps = 27/247 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK-----KNSQVWLGRHN 79 I+GG E H++P+ +V +G CGG L+ QWVL+AAHC+ + QV LG H+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPD--EDSSHDLMLLRLSEPAKITDVVK 137 L PE + V PHP RPD ED DL+L +LS+ A + V+ Sbjct: 61 LSAPEPYKRWYDVQSVVPHP----------GSRPDSLED---DLILFKLSQNASLGPHVR 107 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA-RAYSEKVTE 194 L L ++ + GT C +GWG + RP L + + +++ C R Y + V Sbjct: 108 PLPLQYEDKEVEPGTLCDVAGWGVVT-HAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVT 166 Query: 195 F-MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 M+CA + +DTC GDSG PLVC ++G+ +WG C +KP VYT+V YR WI Sbjct: 167 INMMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWI 224 Query: 254 KDTIAAN 260 ++ N Sbjct: 225 ENITNGN 231 >2F83-A nrPDB Length = 625 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 92/254 (36%), Positives = 130/254 (51%), Gaps = 28/254 (11%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLK-----KNSQ 72 I+ RIVGG + PWQV +++ CGG ++ QW+LTAAHC K + Sbjct: 384 IKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILR 443 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 V+ G N E ++ V H Y M+ +S +D+ LL+L Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVNY 492 Query: 133 TDVVKVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS- 189 TD + + LP++ + T C+ +GWG + + ++ +LQ + L++N+ C + Y Sbjct: 493 TDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRG 551 Query: 190 EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTK 245 K+T M+CAG GGKD C GDSGGPL C N V L GITSWG E CA E+P VYT Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTN 610 Query: 246 VVHYRKWIKDTIAA 259 VV Y WI + A Sbjct: 611 VVEYVDWILEKTQA 624 >3E0N-B nrPDB Length = 271 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 89/253 (35%), Positives = 119/253 (47%), Gaps = 32/253 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I GG PWQV++ G CGG LV QWVL+AAHC K+ +V LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + + + PHP Y E S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQ-----------EGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 GLPTQEPAL--GTTCYASGWGSIEPE-EFLRPRSLQCVSLHLLSNDMCARAYS------- 189 LP + + G C +GWG + P L P+ LQ + + L+S + C Y+ Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 190 -EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYT 244 V E M+CAG GGKD C GDSGGPL C G+ L GI SWG + C +P VYT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTI 257 Y WI+ + Sbjct: 229 LASSYASWIQSKV 241 >3T2N-A nrPDB Length = 372 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 94/261 (36%), Positives = 131/261 (50%), Gaps = 29/261 (11%) Query: 16 GAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL 75 G L RIVGG + PWQV++ G CGG L+ WVLTAAHC + ++V L Sbjct: 109 GRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV-L 167 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLY--NMSLLKHQSLRP-----DEDSSHDLMLLRLSE 128 R +F V+ + PH L +++ H P E++S+D+ L+ LS Sbjct: 168 SRWRVFAG-------AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSS 220 Query: 129 PAKITDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC-- 184 P +T+ ++ + LP AL G C +GWG+ + + LQ + ++SND+C Sbjct: 221 PLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEARVPIISNDVCNG 279 Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQ--------GITSWGPEPCAL 236 A Y ++ M CAG GG D C GDSGGP VC + GI SWG CAL Sbjct: 280 ADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCAL 338 Query: 237 PEKPAVYTKVVHYRKWIKDTI 257 +KP VYTKV +R+WI I Sbjct: 339 AQKPGVYTKVSDFREWIFQAI 359 >3TK9-A nrPDB Length = 226 Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 88/241 (36%), Positives = 120/241 (49%), Gaps = 26/241 (10%) Query: 25 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ V CGG+LV +VLTAAHC + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN ++ S+++MLL+L AK T V+ L L Sbjct: 61 EQERTQQFIPVKRPIPHPAYN-----------PKNFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS---EKVTEFM 196 P+ + + G C +GWG + +LQ V L + + C R + + TE Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTVQKDCQCERLFHGNYSRATE-- 165 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 +C G + GDSGGPLVC V QGI S+G + P VY KV H+ WIK T Sbjct: 166 ICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGT---PPGVYIKVSHFLPWIKRT 222 Query: 257 I 257 + Sbjct: 223 M 223 >3DFJ-A nrPDB Length = 263 Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 89/253 (35%), Positives = 118/253 (46%), Gaps = 32/253 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I GG PWQV++ G CGG LV QWVL+AAHC K+ +V LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + + + PHP Y E S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQ-----------EGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 GLPTQEPAL--GTTCYASGWGSIEPE-EFLRPRSLQCVSLHLLSNDMCARAYS------- 189 LP + G C +GWG + P L P+ LQ + + L+S + C Y+ Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 190 -EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYT 244 V E M+CAG GGKD C GDSGGPL C G+ L GI SWG + C +P VYT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTI 257 Y WI+ + Sbjct: 229 LASSYASWIQSKV 241 >1AZZ-A nrPDB Length = 226 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS--QVWLGRHNLFE 82 IVGG E +S P Q A++ CGG L+ P+W+LTAAHC+ V LG HN+ E Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T + + H YN ++ S+D+ ++RL P +T + +GLP Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVI-----------SNDIAVIRLPVPVTLTAAIATVGLP 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 + + +GT +GWG L+ V + ++SN C Y VT+ +C Sbjct: 110 STDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG-IVTDGNICID-S 167 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 TGGK TC GDSGGPL NG+ GITS+G P +T+V ++ WI+ P Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQTQTGITP 226 >1LTO-A nrPDB Length = 245 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 95/262 (36%), Positives = 130/262 (49%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVA--VYSHGWAH-CGGVLVHPQWVLTAAHCLKKNSQ------VWL 75 IVGG E + PWQV+ V W H CGG L+HPQWVLTAAHCL + + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 +L+ + Q +PVS HP + + + D+ LL L EP I+ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYII-----------QTGADIALLELEEPVNISSR 106 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFL-RPRSLQCVSLHLLSNDMCARAYS--- 189 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 107 VHTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV-LQ-GITSWGPEPCALPEK 239 + + MLCAG +D+C GDSGGPLVC NG LQ G+ SW E CA P + Sbjct: 167 YTGDDVRIIRDDMLCAG--NSQRDSCKGDSGGPLVCKVNGTWLQAGVVSWD-EGCAQPNR 223 Query: 240 PAVYTKVVHYRKWIKDTIAANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >1IAU-A nrPDB Length = 227 Score = 130 bits (327), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 90/241 (37%), Positives = 120/241 (49%), Gaps = 25/241 (10%) Query: 25 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN ++ S+D+MLL+L AK T V+ L L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA---RAYSEKVTEFM 196 P+ + + G TC +GWG P +LQ V + + + C R Y + E Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE-- 166 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 LC G K + GDSGGPLVCN V QGI S+G +P P TKV + WIK T Sbjct: 167 LCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKT 223 Query: 257 I 257 + Sbjct: 224 M 224 >1P57-B nrPDB Length = 255 Score = 130 bits (326), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 91/252 (36%), Positives = 128/252 (50%), Gaps = 29/252 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG + PWQV++ G CGG L+ WVLTAAHC + ++V L R +F Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV-LSRWRVFAGA 59 Query: 85 DTGQRVPVSHSFPHPLY--NMSLLKHQSLRP-----DEDSSHDLMLLRLSEPAKITDVVK 137 V+ + PH L +++ H P E++S+D+ L+ LS P +T+ ++ Sbjct: 60 -------VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQ 112 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC--ARAYSEKVT 193 + LP AL G C +GWG+ + + LQ + ++SND+C A Y ++ Sbjct: 113 PVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEARVPIISNDVCNGADFYGNQIK 171 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQ--------GITSWGPEPCALPEKPAVYTK 245 M CAG GG D C GDSGGP VC + GI SWG CAL +KP VYTK Sbjct: 172 PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTK 230 Query: 246 VVHYRKWIKDTI 257 V +R+WI I Sbjct: 231 VSDFREWIFQAI 242 >2RDL-A nrPDB Length = 226 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 82/244 (33%), Positives = 123/244 (50%), Gaps = 26/244 (10%) Query: 25 IVGGWECEKHSQPW----QVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG EC H++P+ ++ + + C G L+ +V+TAAHC ++ V LG HN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 EDT Q++ V FPHP Y+ L+ +D+MLL+L E A +T V L Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLV-----------LNDIMLLKLKEKANLTLGVGTLP 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRS--LQCVSLHLLSNDMCARAYSEKVTEFM 196 + + ++ G C A GWG E P S LQ V + +L C + + + E Sbjct: 110 ISAKSNSIPPGRVCRAVGWGRTNVNE---PPSDTLQEVKMRILDPQAC-KHFEDFHQEPQ 165 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 LC G ++ GDSGGPL+C G+ QGI S+ + P+V+T++ HYR WI Sbjct: 166 LCVGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVLRNA---KPPSVFTRISHYRPWINKI 222 Query: 257 IAAN 260 + N Sbjct: 223 LREN 226 >6AOD-C nrPDB Length = 245 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 88/250 (35%), Positives = 127/250 (50%), Gaps = 28/250 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLK-----KNSQVWLG 76 IVGG + PWQV +++ CGG ++ QW+LTAAHC K +V+ G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 E ++ V H Y M+ +S +D+ LL+L + TD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVQYTDSQ 109 Query: 137 KVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVT 193 + + LP++ + T C+ +GWG + + ++ +LQ + L++N+ C + Y K+T Sbjct: 110 RPISLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRGHKIT 168 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTKVVHY 249 M+CAG GGKD C GD+GGPL C N V L GITSWG E CA E+P VYT VV Y Sbjct: 169 HKMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEY 227 Query: 250 RKWIKDTIAA 259 WI + A Sbjct: 228 VDWILEKTQA 237 >1SC8-U nrPDB Length = 262 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 83/253 (32%), Positives = 124/253 (49%), Gaps = 32/253 (12%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAH-----CGGVLVHPQWVLTAAHCL-----KKNSQV 73 +I+GG +QPW A+Y CGG L+ P WV++A HC K++ V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP---- 129 +LGR L + V + H Y+ L H + D+ LL++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHN---------DIALLKIRSKEGRC 125 Query: 130 AKITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR- 186 A+ + ++ + LP+ +P GT+C +G+G ++L P L+ + L+S+ C + Sbjct: 126 AQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQP 185 Query: 187 -AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPA 241 Y +VT MLCA D+C GDSGGPLVC+ L GI SWG CAL +KP Sbjct: 186 HYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG-RGCALKDKPG 244 Query: 242 VYTKVVHYRKWIK 254 VYT+V H+ WI+ Sbjct: 245 VYTRVSHFLPWIR 257 >1KYN-A nrPDB Length = 235 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 79/240 (32%), Positives = 113/240 (47%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSH---GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E HS+P+ + G + CGG LV +VLTAAHC N V LG HN+ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E+T Q + + HP YN ++ +D+MLL+LS + V + L Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQ-----------NDIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 P + L GT C +GWG + +L+ V L + + C R + +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 G K GDSGGPL+CN V GI S+G PE V+T+V + WI+ T+ + Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPE---VFTRVSSFLPWIRTTMRS 224 >1FUJ-A nrPDB Length = 221 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 124/246 (50%), Gaps = 39/246 (15%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA---HCGGVLVHPQWVLTAAHCLKKNSQ----VWLGR 77 IVGG E + HS+P+ ++ G CGG L+HP +VLTAAHCL+ Q V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 HN+ E T Q V+ F L N E+ +D++L++LS PA ++ V Sbjct: 61 HNVRTQEPTQQHFSVAQVF---LNNYDA---------ENKLNDILLIQLSSPANLSASVA 108 Query: 138 VLGLPTQEPAL--GTTCYASGWGSI----EPEEFLRPRSLQCVSLHLLSNDMCARAYSEK 191 + LP Q+ + GT C A GWG + P + L+ ++ V+ +++C K Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 168 Query: 192 VTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRK 251 AG+ C GDSGGPL+C+G++QGI S+ CA P +T+V Y Sbjct: 169 -------AGI-------CFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 214 Query: 252 WIKDTI 257 WI+ T+ Sbjct: 215 WIRSTL 220 >1YC0-A nrPDB Length = 283 Score = 123 bits (309), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 89/256 (34%), Positives = 125/256 (48%), Gaps = 31/256 (12%) Query: 20 LIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVW 74 ++ RI+GG S PW A+Y G + C G LVH WV++AAHC + + V Sbjct: 31 FLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVV 89 Query: 75 LGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP----A 130 LG+H D Q + P+ LY++ S HDL+L+RL + A Sbjct: 90 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVF----------NPSDHDLVLIRLKKKGDRCA 139 Query: 131 KITDVVKVLGLP---TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA-- 185 + V+ + LP + PA G C +GWG ++ SL+ + L+++ C+ Sbjct: 140 TRSQFVQPICLPEPGSTFPA-GHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSP 198 Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPA 241 Y ++ MLCAG + D C GDSGGPL C NGV L GI SWG + C KP Sbjct: 199 EVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPG 257 Query: 242 VYTKVVHYRKWIKDTI 257 VYT+V +Y WI D I Sbjct: 258 VYTRVANYVDWINDRI 273 >5GVT-A nrPDB Length = 250 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/241 (35%), Positives = 119/241 (49%), Gaps = 22/241 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLKK--NSQVWLGRHN 79 IVGG PWQV++ + CGG ++ QWVLTAAHC VW Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 + + + P S L+ HQ + E ++D+ L++L P T+ K + Sbjct: 61 ILSLSEITKETPSSRI-------KELIIHQEYKVSE-GNYDIALIKLQTPLNYTEFQKPI 112 Query: 140 GLPTQEPA--LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKV-TEFM 196 LP++ + T C+ +GWG + E+ LQ ++ L+ N+ C + Y + V + M Sbjct: 113 SLPSKADTNTIYTNCWVTGWGYTK-EQGETQNILQKATIPLVPNEECQKKYRDYVINKQM 171 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGV----LQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 +CAG GG D C GDSGGPLVC L GITSWG E CA ++P VYTKV Y W Sbjct: 172 ICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWG-EGCARKDQPGVYTKVSEYMDW 230 Query: 253 I 253 I Sbjct: 231 I 231 >2V35-A nrPDB Length = 240 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/251 (34%), Positives = 129/251 (51%), Gaps = 26/251 (10%) Query: 25 IVGGWECEKHSQPWQVAV-YSHG--WAH-CGGVLVHPQWVLTAAHCLKK--NSQVWLGRH 78 +VGG E +++S P Q+++ Y G WAH CGG L+ WV+TAAHC+ + +V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 NL + + T Q V V HP +N D + +D+ LLRL++ + V++ Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTD---------DVAAGYDIALLRLAQSVTLNSYVQL 111 Query: 139 LGLPTQEPALGTT--CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP L CY +GWG L ++LQ L + +C+ + + V Sbjct: 112 GVLPRAGTILANNSPCYITGWGLTRTNGQL-AQTLQQAYLPTVDYAICSSSSYWGSTVKN 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC--NG--VLQGITSWGPE-PCALPEKPAVYTKVVHY 249 M+CAG G + C GDSGGPL C NG + G+TS+ C + KP V+T+V Y Sbjct: 171 SMVCAG-GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAY 229 Query: 250 RKWIKDTIAAN 260 WI + IA+N Sbjct: 230 ISWINNVIASN 240 >1BRU-P nrPDB Length = 241 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 89/252 (35%), Positives = 125/252 (49%), Gaps = 27/252 (10%) Query: 25 IVGGWECEKHSQPWQVAVY---SHGWAH-CGGVLVHPQWVLTAAHCL--KKNSQVWLGRH 78 +VGG + +S PWQV++ S W H CGG LV WVLTAAHC+ + +V LGRH Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 +L E V VS H +N + L + +D+ LL+L+ P +TD +++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSN---------GNDIALLKLASPVSLTDKIQL 111 Query: 139 LGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP L CY +GWG ++ P LQ L ++ C++ + V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRLQTNG-ASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGV-----LQGITSWGPE-PCALPEKPAVYTKVVH 248 M+CAG G +C GDSGGPL C G + GI S+G C KP+V+T+V + Sbjct: 171 NMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 YRKWIKDTIAAN 260 Y WI IA N Sbjct: 230 YIDWINSVIANN 241 >2ZKS-A nrPDB Length = 240 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 85/241 (35%), Positives = 119/241 (49%), Gaps = 23/241 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS---QVWLGRHNLF 81 I+GG E HS+P+ ++ +G CGGVLVHP+WVLTAAHCL + ++ LG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 P G + + HP Y +P +DL LL+L K + ++ L L Sbjct: 61 SP---GLTFHIKAAIQHPRY----------KPVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC--ARAYSEKVTEFML 197 P+ Q A GT C +GWG L R L+ + L +L MC +R ++ ++ M+ Sbjct: 108 PSKRQVVAAGTRCSMAGWGLTHQGGRL-SRVLRELDLQVLDTRMCNNSRFWNGSLSPSMV 166 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNG--VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 C + + C GDSGGPLVC VL G+ S+ C KP V T V Y WI+ Sbjct: 167 CLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 226 Query: 256 T 256 Sbjct: 227 V 227 >2R0L-A nrPDB Length = 248 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 89/251 (35%), Positives = 123/251 (49%), Gaps = 31/251 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I+GG S PW A+Y G + C G LVH WV++AAHC + + V LG+H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP----AKITDV 135 D Q + P+ LY++ P S HDL+L+RL + A + Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSV-------FNP---SDHDLVLIRLKKKGDRCATRSQF 109 Query: 136 VKVLGLP---TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSE 190 V+ + LP + PA G C +GWG ++ SL+ + L+++ C+ Y Sbjct: 110 VQPICLPEPGSTFPA-GHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGA 168 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTKV 246 ++ MLCAG + D C GDSGGPL C NGV L GI SWG + C KP VYT+V Sbjct: 169 DISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGVYTRV 227 Query: 247 VHYRKWIKDTI 257 +Y WI D I Sbjct: 228 ANYVDWINDRI 238 >3RP2-A nrPDB Length = 224 Score = 120 bits (300), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 86/244 (35%), Positives = 121/244 (49%), Gaps = 32/244 (13%) Query: 25 IVGGWECEKHSQPWQV---AVYSHGW-AHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG E HS+P+ V G CGG L+ Q+VLTAAHC + V LG H++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 + E T Q++ V H YN + HD+MLL+L + ++T V V+ Sbjct: 61 RKRESTQQKIKVEKQIIHESYN-----------SVPNLHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTQEPAL--GTTCYASGWGSI---EPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVT 193 LP+ + G C+A+GWG +P + +L+ V L ++ C R Y K Sbjct: 110 LPSPSDFIHPGAMCWAAGWGKTGVRDPTSY----TLREVELRIMDEKACVDYRYYEYK-- 163 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 F +C G T + GDSGGPL+C GV GI S+G P A P PA++T+V Y WI Sbjct: 164 -FQVCVGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYG-HPDAKP--PAIFTRVSTYVPWI 219 Query: 254 KDTI 257 I Sbjct: 220 NAVI 223 >5LHN-A nrPDB Length = 247 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 83/260 (31%), Positives = 127/260 (48%), Gaps = 39/260 (15%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA------HCGGVLVHPQWVLTAAHCL-----KKNSQV 73 IVGG E +QPW A+Y CGG L+ P WV +AAHC K+N V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 WLG--RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH-DLMLLRL---- 126 +LG + + + P + V L+ H+ R D + H D+ LL++ Sbjct: 61 YLGQSKESSYNPGEMKFEVE------------QLILHEYYREDSLAYHNDIALLKIRTST 108 Query: 127 SEPAKITDVVKVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 + A+ + ++ + LP + + G+ C +G+G ++L P++L+ + L+S++ C Sbjct: 109 GQCAQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQC 168 Query: 185 AR--AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPE 238 + Y ++ MLCA D+C GDSGGPL+CN L GI SWG CA Sbjct: 169 MQPHYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKN 227 Query: 239 KPAVYTKVVHYRKWIKDTIA 258 KP VYT+V H+ WI+ I Sbjct: 228 KPGVYTRVSHFLDWIQSHIG 247 >4Z6A-H nrPDB Length = 249 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 85/251 (33%), Positives = 119/251 (47%), Gaps = 27/251 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 IVGG C K PWQV + +G CGG L++ WV++AAHC K N LG H+ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L E + Q V+ Y ++HD+ LLRL +P +TD V L Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPG-----------TTNHDIALLRLHQPVVLTDHVVPL 109 Query: 140 GLPTQEPALGTTCY-----ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE 194 LP + + T + SGWG + + L +++ L C +Y K+TE Sbjct: 110 CLPERTFSERTLAFVRFSLVSGWGQLL-DRGATALELMVLNVPRLMTQDCEASYPGKITE 168 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVHYR 250 +M CAG G KD+C GDSGGP + L GI SWG + CA VYT+V Y Sbjct: 169 YMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYI 227 Query: 251 KWIKDTIAANP 261 +W++ + + P Sbjct: 228 EWLQKLMRSEP 238 >3F6U-H nrPDB Length = 240 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 121/246 (49%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVAVY-SHGWAHCGGVLVHPQWVLTAAHCLKKNSQ--VWLGRHNLF 81 ++ G + PWQV + S CG VL+HP WVLTAAHC+ ++ + V LG ++L Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E + + F HP Y+ S + +D+ LL L++PA ++ + + L Sbjct: 61 RWEKWELDLDIKEVFVHPNYSKST-----------TDNDIALLHLAQPATLSQTIVPICL 109 Query: 142 PTQEPA------LGTTCYASGWG--SIEPEEFLRPRS--LQCVSLHLLSNDMCARAYSEK 191 P A G +GWG S +E R R+ L + + ++ ++ C+ S Sbjct: 110 PDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM 169 Query: 192 VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVV 247 V+E MLCAG+ +D C GDSGGP+V + L G+ SWG E C L VYTKV Sbjct: 170 VSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVS 228 Query: 248 HYRKWI 253 Y WI Sbjct: 229 RYLDWI 234 >2XRC-A nrPDB Length = 565 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 90/267 (33%), Positives = 122/267 (45%), Gaps = 45/267 (16%) Query: 10 LSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK 69 LS G + + + RIVGG + PWQVA+ CGG+ + W+LTAAHCL+ Sbjct: 307 LSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA 366 Query: 70 NS----QVWLGRHNLFEPEDTGQRVPVSHS---FPHPLYNMSLLKHQSLRPDEDSSHDLM 122 + Q+W + P+ +R+ + + H YN + +D+ Sbjct: 367 SKTHRYQIWTTVVDWIHPD--LKRIVIEYVDRIIFHENYNAGTYQ-----------NDIA 413 Query: 123 LLRLSEPAKITDVVKVLGLPTQEPAL----------GTTCYASGWGSIEPEEFLRPRSLQ 172 L+ + + D LP PA TC SGWG + E R SLQ Sbjct: 414 LIEMKKDGNKKDC----ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQ 467 Query: 173 CVSLHLLSNDMCARAYSEKVTEF-MLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ--GI 226 + L+SN C++ Y + E M CAG + G D C GDSGGPLVC N V G+ Sbjct: 468 WGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGV 525 Query: 227 TSWGPEPCALPEKPAVYTKVVHYRKWI 253 SWG E C PE P VYTKV +Y WI Sbjct: 526 VSWG-ENCGKPEFPGVYTKVANYFDWI 551 >4DGJ-A nrPDB Length = 235 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 122/246 (49%), Gaps = 31/246 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGRH 78 IVGG + ++ + PW V +Y CG LV W+++AAHC+ + LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 ---NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 NL P+ + P + + + H + R ++ D+ ++ L TD Sbjct: 61 MKSNLTSPQ----------TVPRLIDEIVINPHYNRRRKDN---DIAMMHLEFKVNYTDY 107 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KV 192 ++ + LP + G C +GWG++ + LQ + LLSN+ C + E + Sbjct: 108 IQPISLPEENQVFPPGRNCSIAGWGTV-VYQGTTADILQEADVPLLSNERCQQQMPEYNI 166 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVH 248 TE M+CAG GG D+C GDSGGPL+C L G+TS+G E CALP +P VY +V Sbjct: 167 TENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSR 225 Query: 249 YRKWIK 254 + +WI+ Sbjct: 226 FTEWIQ 231 >4Q7Y-A nrPDB Length = 250 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 116/241 (48%), Gaps = 20/241 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 80 I+GG E HS+P+ +V G HCGG L+ +WV++AAHC + V LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E T Q + HP Y+ + H ++D+ LLRL+ A + V +L Sbjct: 61 STAEPTQQVFGIDALTTHPDYHP--MTH---------ANDICLLRLNGSAVLGPAVGLLR 109 Query: 141 LPTQE---PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 197 LP + P GT C +GWG + E L P L + +L D+C ++ +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAGLW-TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 C + + C DSGGPLVC G+ S+ C P+ P VYT+V + WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 I 257 + Sbjct: 229 V 229 >2OQ5-A nrPDB Length = 232 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 118/244 (48%), Gaps = 33/244 (13%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRHNL-F 81 IVGG E E+ PWQ ++ G CG L++ W+++AAHC KN W + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 82 EPEDTG---QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 +P +R+ V + HP ++ +D+ L LS P T+ V Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHD----------------YDISLAELSSPVPYTNAVHR 104 Query: 139 LGLP--TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVTE 194 + LP + E G + +G+G+++ + + + L+ + L+ C +AY++ +T Sbjct: 105 VCLPDASYEFQPGDVMFVTGFGALKNDGYSQ-NHLRQAQVTLIDATTCNEPQAYNDAITP 163 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGV-----LQGITSWGPEPCALPEKPAVYTKVVHY 249 MLCAG G D C GDSGGPLV + L GI SWG E CA P KP VYT+V Sbjct: 164 RMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTAL 222 Query: 250 RKWI 253 R WI Sbjct: 223 RDWI 226 >2KAI-A nrPDB Length = 80 Score = 114 bits (284), Expect = 5e-26, Method: Composition-based stats. Identities = 50/80 (62%), Positives = 61/80 (76%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GG ECEK+S PWQVA+Y + CGGVLV+P+WVLTAAHC N +VWLGRHNLFE E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 DTGQRVPVSHSFPHPLYNMS 104 +T Q V+ FPHP +N+S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >1EKB-B nrPDB Length = 235 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 123/249 (49%), Gaps = 31/249 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGRH 78 IVGG + + + PW VA+Y CG LV W+++AAHC+ + + LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 ---NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 NL P+ + + PH YN ++D+ ++ L TD Sbjct: 61 MASNLTSPQIETRLIDQIVINPH--YN-----------KRRKNNDIAMMHLEMKVNYTDY 107 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KV 192 ++ + LP + G C +GWG++ + LQ + LLSN+ C + E + Sbjct: 108 IQPICLPEENQVFPPGRICSIAGWGAL-IYQGSTADVLQEADVPLLSNEKCQQQMPEYNI 166 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVH 248 TE M+CAG GG D+C GDSGGPL+C +L G+TS+G + CALP +P VY +V Sbjct: 167 TENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPR 225 Query: 249 YRKWIKDTI 257 + +WI+ + Sbjct: 226 FTEWIQSFL 234 >5KWM-A nrPDB Length = 230 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/240 (35%), Positives = 113/240 (47%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQVA-VYSHGWAHCGGVLVHPQWVLTAAHCL----KKNSQVWLGRHN 79 IVGG + P+ VA V G CGG L P V+TAAHC + V GR Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 + E T +V ++ + HP Y D D+ +L L P K + ++ Sbjct: 61 MSSNEGTVSKV--TNVWVHPEYQ-----------DAAKGFDVSVLTLEAPVKEAPI-ELA 106 Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 A T GWG+ E + LQ ++ + S+D C +AY E + M+CA Sbjct: 107 KADDAGYAPDTAATILGWGNTS-EGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCA 165 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 G+ GG DTC GDSGGP+V N L G+TSWG E CA P KP VY +V Y + + I A Sbjct: 166 GVPEGGVDTCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYDVLMEQINA 224 >3P8G-A nrPDB Length = 241 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 32/251 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVLTAAHCLKKNS----------QV 73 +VGG + ++ PWQV++++ G H CG L+ P W+++AAHC + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 WLGRHNLFEPEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 +LG H+ + G Q + HP +N D +D+ LL L +PA+ Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFN-----------DFTFDYDIALLELEKPAEY 109 Query: 133 TDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + +V+ + LP G + +GWG + LQ + ++ C + Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGHTQ-YGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQ-GITSWGPEPCALPEKPAVYTK 245 ++T M+C G +GG D+C GDSGGPL + Q G+ SWG + CA KP VYT+ Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTR 227 Query: 246 VVHYRKWIKDT 256 + +R WIK+ Sbjct: 228 LPLFRDWIKEN 238 >5O32-I nrPDB Length = 244 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 83/245 (33%), Positives = 116/245 (47%), Gaps = 31/245 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS----QVWLGRHNL 80 IVGG + PWQVA+ CGG+ + W+LTAAHCL+ + Q+W + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 P+ +R+ + Y ++ H++ +D+ L+ + + D Sbjct: 61 IHPDL--KRIVIE-------YVDRIIFHENYNAGT-YQNDIALIEMKKDGNKKDCELPRS 110 Query: 141 LPTQEP------ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE 194 +P P TC SGWG + E R SLQ + L+SN C++ Y + E Sbjct: 111 IPACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKFYGNRFYE 166 Query: 195 F-MLCAGLWTGGKDTCGGDSGGPLVC---NGV--LQGITSWGPEPCALPEKPAVYTKVVH 248 M CAG + G D C GDSGGPLVC N V + G+ SWG E C PE P VYTKV + Sbjct: 167 KEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVAN 225 Query: 249 YRKWI 253 Y WI Sbjct: 226 YFDWI 230 >4IGD-A nrPDB Length = 406 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/263 (29%), Positives = 123/263 (46%), Gaps = 44/263 (16%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSH--GWAHCGGVLVHPQWVLTAAHCLKK--------- 69 + ++I G +K + PW +A+ SH G CGG L+ W++TAAHCL + Sbjct: 152 LMAQIFNGRPAQKGTTPW-IAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTL 210 Query: 70 ---------NSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 + ++ LG+H ++ Q + V H+ HP Y+ + ++ D Sbjct: 211 RDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFEN-----------D 259 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 + L+ L E + V + LP G SGWG + F P +L + + ++ Sbjct: 260 VALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVD 317 Query: 181 NDMCARAYS---EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGP 231 + C +AY+ +KVT M+CAG GGKD C GDSGGP+V L G SWG Sbjct: 318 HSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG- 376 Query: 232 EPCALPEKPAVYTKVVHYRKWIK 254 + C ++ VY+ + H + WI+ Sbjct: 377 DDCGKKDRYGVYSYIHHNKDWIQ 399 >4XDE-A nrPDB Length = 257 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 90/257 (35%), Positives = 118/257 (45%), Gaps = 44/257 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLK-----KNSQVWLG- 76 +VGG + + P+ A+Y W H C G L+ P WVLTAAHCL+ ++ V LG Sbjct: 3 VVGGLVALRGAHPYIAALY---WGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQ 59 Query: 77 --RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK--- 131 R++ EP T L S H++ P HDL LLRL E A Sbjct: 60 ERRNHSCEPCQT-------------LAVRSYRLHEAFSP-VSYQHDLALLRLQEDADGSC 105 Query: 132 --ITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA-- 185 ++ V+ + LP+ P+ T C +GWG LQ + LS + C+ Sbjct: 106 ALLSPYVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAP 165 Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPE 238 + + MLCAG GG D C GDSGGPLVC LQGI SWG C Sbjct: 166 DVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWG-SGCGDRN 224 Query: 239 KPAVYTKVVHYRKWIKD 255 KP VYT V +Y WI++ Sbjct: 225 KPGVYTDVAYYLAWIRE 241 >3W94-A nrPDB Length = 235 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 83/245 (33%), Positives = 121/245 (49%), Gaps = 25/245 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-KKNS--QVW---LGRH 78 +VGG EK + PW V+++ G CG L+ W+LTAAHC+ KN+ Q W LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 + Q V + + + + K+ + R E D+ ++ L +P T+ V Sbjct: 61 A--QSSMNSQEVQIRQ-----VDRIIINKNYNRRTKE---ADIAMMHLQQPVNFTEWVLP 110 Query: 139 LGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVTEF 195 + L +++ G C+ +GWG + E P LQ + L+ D C R E T Sbjct: 111 VCLASEDQHFPAGRRCFIAGWGR-DAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSS 169 Query: 196 MLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYRK 251 MLCAG GG D+C GDSGGPL+C L G+TS+G C PE+P Y +V + Sbjct: 170 MLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTS 228 Query: 252 WIKDT 256 WI +T Sbjct: 229 WIAET 233 >2F91-A nrPDB Length = 237 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 76/246 (30%), Positives = 118/246 (47%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVAV----YSHGWAHCGGVLVHPQWVLTAAHCLKKNS-------QV 73 IVGG + P+Q++ + CG + + + +TA HC+ + Q+ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 G ++ E + Q + VS H ++ +LL + D+ LL+LS Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDN-----------DISLLKLSGSLTFN 109 Query: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKV 192 D V + LP Q +GWG+ E P LQ V++ L+S++ C Y ++++ Sbjct: 110 DNVAPIALPEQGHTATGDVIVTGWGTTS-EGGNTPDVLQKVTVPLVSDEDCRADYGADEI 168 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNGV----LQGITSWGPEPCALPEKPAVYTKVVH 248 + M+CAG+ GGKD+C GDSGGPL + L GI SWG CA P P VYT+V + Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSY 227 Query: 249 YRKWIK 254 + WIK Sbjct: 228 HVDWIK 233 >4DJZ-B nrPDB Length = 251 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 44/259 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSH--GWAHCGGVLVHPQWVLTAAHCLKK------------- 69 I G +K + PW +A+ SH G CGG L+ W++TAAHCL + Sbjct: 1 IFNGRPAQKGTTPW-IAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSD 59 Query: 70 -----NSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 + ++ LG+H ++ Q + V H+ HP Y+ + ++ D+ L+ Sbjct: 60 LLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFEN-----------DVALV 108 Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 L E + V + LP G SGWG + F P +L + + ++ + C Sbjct: 109 ELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDHSTC 166 Query: 185 ARAYS---EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCA 235 +AY+ +KVT M+CAG GGKD C GDSGGP+V L G SWG + C Sbjct: 167 QKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG-DDCG 225 Query: 236 LPEKPAVYTKVVHYRKWIK 254 ++ VY+ + H + WI+ Sbjct: 226 KKDRYGVYSYIHHNKDWIQ 244 >1AE5-A nrPDB Length = 225 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 113/243 (46%), Gaps = 29/243 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN----SQVWLGRHNL 80 IVGG + P+ ++ + G CGG L+H ++V+TAA C + S V LG ++L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E ++ +++S + P ++ +DLMLL+L A +T V +L Sbjct: 61 RRRERQSRQT----------FSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILP 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 LP Q + GT C +GWGS L R + V++ + D C +C Sbjct: 110 LPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNVC 160 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G+ T C GD G PLVC G+ G+ S+ PC P +T+V +R WI D + Sbjct: 161 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWI-DGVL 217 Query: 259 ANP 261 NP Sbjct: 218 NNP 220 >1AKS-B nrPDB Length = 98 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 52/93 (55%), Positives = 62/93 (66%), Gaps = 1/93 (1%) Query: 168 PRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGIT 227 P LQC+ +LSN C +Y ++T M+C G GGKD+C GDSGGP+VCNG LQGI Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIV 66 Query: 228 SWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 SWG CA KP VYTKV +Y WI+ TIAAN Sbjct: 67 SWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1BDA-A nrPDB Length = 265 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 85/265 (32%), Positives = 119/265 (44%), Gaps = 41/265 (15%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAH------CGGVLVHPQWVLTAAHCLKKNS---- 71 Q RI GG + S PWQ A+++ CGG+L+ W+L+AAHC ++ Sbjct: 11 QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHH 70 Query: 72 -QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRL---- 126 V LGR P + Q+ V H ++ D+ +D+ LL+L Sbjct: 71 LTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD-----------DDTYDNDIALLQLKSDS 119 Query: 127 SEPAKITDVVKVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 S A+ + VV+ + LP + L T C SG+G E L+ + L + C Sbjct: 120 SRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRC 179 Query: 185 ARAY--SEKVTEFMLCAGLWTGG------KDTCGGDSGGPLVC----NGVLQGITSWGPE 232 + + VT+ MLCAG G D C GDSGGPLVC L GI SWG Sbjct: 180 TSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL- 238 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C + P VYTKV +Y WI+D + Sbjct: 239 GCGQKDVPGVYTKVTNYLDWIRDNM 263 >1MKW-K nrPDB Length = 308 Score = 106 bits (265), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 85/269 (31%), Positives = 122/269 (45%), Gaps = 43/269 (15%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL-----KKNSQ- 72 I+ RIV G + E PWQV ++ CG L+ +WVLTAAHCL KN Sbjct: 46 IEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 73 ----VWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 V +G+H+ E +++ + + HP YN E+ D+ LL+L Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLK 155 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCVSLH 177 P +++D + + LP ++ A G +GWG+ ++P LQ V+L Sbjct: 156 RPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLP 215 Query: 178 LLSNDMCARAYSEKVTEFMLCAGLWTG-GK--DTCGGDSGGPLVCNG------VLQGITS 228 L+ +C + ++T+ M CAG G GK D C GDSGGP V GI S Sbjct: 216 LVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVS 275 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 276 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >2OCV-B nrPDB Length = 259 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 117/265 (44%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV GW+ EK PWQV ++ CG L+ +WVLTAAHC+ + + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ LL+L +P Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 ITDVVKVLGLPTQEPAL-----GTTCYASGWGSIEPE-----EFLRPRSLQCVSLHLLSN 181 +D + + LP ++ G +GWG++ ++P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVER 170 Query: 182 DMCARAYSEKVTEFMLCAGLW---TGGKDTCGGDSGGPLVCNGVLQ------GITSWGPE 232 +C + ++T+ M CAG T D C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-E 229 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V + WI+ I Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >1A5I-A nrPDB Length = 265 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 83/261 (31%), Positives = 119/261 (45%), Gaps = 41/261 (15%) Query: 26 VGGWECEKHSQPWQVAVYSHGWAH------CGGVLVHPQWVLTAAHCLKKNS-----QVW 74 GG + S PWQ A+++ CGG+L+ WVLTAAHC +++ +V Sbjct: 15 TGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVV 74 Query: 75 LGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP----A 130 LGR +P + Q V H ++ D+ ++D+ LL+L A Sbjct: 75 LGRTYRVKPGEEEQTFKVKKYIVHKEFD-----------DDTYNNDIALLQLKSDSPQCA 123 Query: 131 KITDVVKVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA- 187 + +D V+ + LP L T C SG+G + L+ + L + CA Sbjct: 124 QESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKF 183 Query: 188 -YSEKVTEFMLCAGLWTGGK------DTCGGDSGGPLVCNG----VLQGITSWGPEPCAL 236 +++ VT MLCAG G+ D C GDSGGPLVC L GI SWG C Sbjct: 184 LFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGE 242 Query: 237 PEKPAVYTKVVHYRKWIKDTI 257 + P VYTKV +Y WI+D + Sbjct: 243 KDVPGVYTKVTNYLGWIRDNM 263 >1PYT-D nrPDB Length = 251 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 83/263 (31%), Positives = 129/263 (49%), Gaps = 45/263 (17%) Query: 19 PLIQSRIVGGWECEKHSQPWQVAV---YSHGWAH-CGGVLVHPQWVLTAAHCLKK--NSQ 72 P + +R+VGG + HS PWQ+++ + W H CGG L+ P VLTAAHC+ + Sbjct: 8 PNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYR 67 Query: 73 VWLGRHNL-FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V LG++NL E E V V F H +N L++ +D+ L++L+E + Sbjct: 68 VALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVR-----------NDIALIKLAETVE 116 Query: 132 ITDVVKVLGLPTQEPAL--GTTCYASGWGSI--------EPEEFLRPRSLQCVSLHLLSN 181 + D ++V LP++ L C+ +GWG + E ++ L+P ++ Sbjct: 117 LGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQP---------VVDY 167 Query: 182 DMCARA--YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPE-PC 234 C++ + V E M+CAG G C GDSGGPL C ++GI S+G C Sbjct: 168 ATCSQRDWWGTTVKETMVCAG-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSC 226 Query: 235 ALPEKPAVYTKVVHYRKWIKDTI 257 +KP V+T+V Y WI + Sbjct: 227 NTFKKPTVFTRVSAYIDWINQKL 249 >4H4F-A nrPDB Length = 249 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 129/250 (51%), Gaps = 30/250 (12%) Query: 25 IVGGWECEKHSQPWQVAVY---SHGWAH-CGGVLVHPQWVLTAAHCLK--KNSQVWLGRH 78 +VGG + HS PWQ+++ + W H CGG L+ +VLTAAHC+ + +V +G++ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 NL-FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 NL E E+ V V H +N LL+ +D+ L++L+E +++D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 109 Query: 138 VLGLPTQEPALGTT--CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVT 193 V LP ++ L CY +GWG + + + Q + ++ + C+R + +V Sbjct: 110 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVK 168 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ--GITSWGPEP-CALPEKPAVYTKVV 247 + M+CAG G C GDSGGPL C NG + GI S+G C +KP VYT+V Sbjct: 169 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 248 HYRKWIKDTI 257 Y WI + + Sbjct: 228 AYIDWINEKM 237 >1ELT-A nrPDB Length = 236 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 118/245 (48%), Gaps = 27/245 (11%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAH---CGGVLVHPQWVLTAAHCLK--KNSQVWLGRH 78 +VGG + +S PWQ+++ Y G ++ CGG L+ WV+TAAHC+ + +V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 NL E Q + V+ F H +N D +D+ LLRL+ A + V++ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWN---------SDDVAGGYDIALLRLNTQASLNSAVQL 111 Query: 139 LGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP L CY +GWG L SL+ L + + C+ + + V Sbjct: 112 AALPPSNQILPNNNPCYITGWGKTSTGGPLS-DSLKQAWLPSVDHATCSSSGWWGSTVKT 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC--NG--VLQGITSW-GPEPCALPEKPAVYTKVVHY 249 M+CAG G C GDSGGPL C NG + G+TS+ C +KP V+T+V Y Sbjct: 171 TMVCAG--GGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAY 228 Query: 250 RKWIK 254 W+ Sbjct: 229 ISWMN 233 >1FIZ-A nrPDB Length = 263 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 118/254 (46%), Gaps = 21/254 (8%) Query: 25 IVGGWECEKHSQPWQVAVY------SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRH 78 +VGG E + PW V++ + + CGG+L++ WVLTAAHC K +V R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 NLFEPEDT-GQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 E G PV ++ + + E +D+ L++++ P + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLE--INDIALIKITPPVPCGPFIG 118 Query: 138 VLGLPTQE---PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC--ARAYSEKV 192 LP + P TC+ +GWG ++ + +LQ + L+ ++C R Y+ ++ Sbjct: 119 PGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRI 178 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAVYTKV 246 +CAG G DTC GDSGGPL+C V+ GITSWG CA ++P VYT Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTST 237 Query: 247 VHYRKWIKDTIAAN 260 Y WI I +N Sbjct: 238 WPYLNWIASKIGSN 251 >3NXP-A nrPDB Length = 424 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 81/269 (30%), Positives = 120/269 (44%), Gaps = 43/269 (15%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------K 68 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL + Sbjct: 162 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 69 KNSQVWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V +G+H+ E +++ + + HP YN E+ D+ L++L Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 271 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPEEFL-----RPRSLQCVSLH 177 +P +D + + LP +E A G +GWG+++ +P LQ V+L Sbjct: 272 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 331 Query: 178 LLSNDMCARAYSEKVTEFMLCAGLW-TGGK--DTCGGDSGGPLVCNGVLQ------GITS 228 ++ +C + ++T+ M CAG GK D C GDSGGP V GI S Sbjct: 332 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 391 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 392 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 419 >1PQ7-A nrPDB Length = 224 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 109/239 (45%), Gaps = 20/239 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLG-RHNLFEP 83 IVGG P+ V++ +G CGG L++ VLTAAHC+ +Q R Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE--PAKITDVVKVLGL 141 G +S HP Y +++DL +L+LS P+ L Sbjct: 61 TSGGITSSLSSVRVHPSY-------------SGNNNDLAILKLSTSIPSGGNIGYARLAA 107 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFMLCAG 200 +P G++ +GWG+ P +L V++ ++S C Y + +T M CAG Sbjct: 108 SGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAG 167 Query: 201 LWTGGKDTCGGDSGGPLV-CNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 + +GGKD+C GDSGGP+V + L G SWG CA P VY V R +I DT A Sbjct: 168 VSSGGKDSCQGDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFI-DTYA 224 >3K65-B nrPDB Length = 308 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/269 (29%), Positives = 120/269 (44%), Gaps = 43/269 (15%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------K 68 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL + Sbjct: 46 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 69 KNSQVWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V +G+H+ E +++ + + HP YN E+ D+ L++L Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 155 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPEEFL-----RPRSLQCVSLH 177 +P +D + + LP +E A G +GWG+++ +P LQ V+L Sbjct: 156 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 215 Query: 178 LLSNDMCARAYSEKVTEFMLCAGLW-TGGK--DTCGGDSGGPLVCNGVLQ------GITS 228 ++ +C + ++T+ M CAG GK D C GD+GGP V GI S Sbjct: 216 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVS 275 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 276 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >4NZQ-A nrPDB Length = 557 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 81/269 (30%), Positives = 120/269 (44%), Gaps = 43/269 (15%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------K 68 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL + Sbjct: 295 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 69 KNSQVWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V +G+H+ E +++ + + HP YN E+ D+ L++L Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 404 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPEEFL-----RPRSLQCVSLH 177 +P +D + + LP +E A G +GWG+++ +P LQ V+L Sbjct: 405 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 464 Query: 178 LLSNDMCARAYSEKVTEFMLCAGLW-TGGK--DTCGGDSGGPLVCNGVLQ------GITS 228 ++ +C + ++T+ M CAG GK D C GDSGGP V GI S Sbjct: 465 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 524 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 525 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 552 >1Q3X-A nrPDB Length = 328 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/260 (30%), Positives = 119/260 (45%), Gaps = 44/260 (16%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGR 77 RI GG + + PWQV + G G L++ WVLTAAH + + + +G Sbjct: 86 RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 143 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 P T ++ ++ H+ D +D+ L++L+ I + Sbjct: 144 LKRLSPHYT------------QAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNIT 191 Query: 138 VLGLPTQEPA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + LP +E +GT ASGWG + FL R+L V + ++ + C AY + Sbjct: 192 PICLPRKEAESFMRTDDIGT---ASGWG-LTQRGFL-ARNLMYVDIPIVDHQKCTAAYEK 246 Query: 191 ------KVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEPCALPE 238 VT MLCAGL +GGKD+C GDSGG LV + GI SWG C Sbjct: 247 PPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAG 306 Query: 239 KPAVYTKVVHYRKWIKDTIA 258 + VYTKV++Y WI++ I+ Sbjct: 307 QYGVYTKVINYIPWIENIIS 326 >1ETT-H nrPDB Length = 259 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 83/265 (31%), Positives = 119/265 (44%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL-----KKNSQ----- 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL KN Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVP-VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ LL+L P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCVSLHLLSN 181 ++D + + LP ++ A G +GWG+ ++P LQ V+L L+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 170 Query: 182 DMCARAYSEKVTEFMLCAGLWTG-GK--DTCGGDSGGPLVCNG------VLQGITSWGPE 232 +C + ++T+ M CAG G GK D C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG-E 229 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V +KWI+ I Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >1FIW-A nrPDB Length = 290 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 117/254 (46%), Gaps = 21/254 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH------CGGVLVHPQWVLTAAHCLKKNSQVWLGRH 78 I+GG + + PW V++ + + CGG L++ QW+LTAAHC + +V R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 NLFEPE-DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 E + G PV Y ++ H+ ++ +D+ L++++ P + Sbjct: 61 IFGAKEVEWGTNKPVKPPL-QERYVEKIIIHEKYSASSEA-NDIALMKITPPVTCGHFIG 118 Query: 138 VLGLPTQE---PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC--ARAYSEKV 192 LP P + TC+ +GWG ++ LQ + L+ +C R Y+ ++ Sbjct: 119 PGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRI 178 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAVYTKV 246 +CAG G DTC GDSGGPL+C V+ GITSWG CA ++P VYT Sbjct: 179 RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVG-CARAKRPGVYTST 237 Query: 247 VHYRKWIKDTIAAN 260 Y WI I + Sbjct: 238 WSYLNWIASKIGST 251 >1FON-A nrPDB Length = 240 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 81/248 (32%), Positives = 125/248 (50%), Gaps = 36/248 (14%) Query: 34 HSQPWQVAVY--SHGWAH--CGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLFEPEDTG 87 +S WQV++ G H CGG L+ P WV+TA HC+ + QV LG ++ E + Sbjct: 8 YSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRSVLEGSE 67 Query: 88 QRVPVSHS--FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQE 145 Q +P++ F HPL+N + + +D+ L++LS A++ D V++ LP Sbjct: 68 QVIPINAGDLFVHPLWNSNCVA---------CGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 146 PALGTT--CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYSEKVTEFMLCAGL 201 L CY SGWG + L P LQ L + + C++ + V + M+CAG Sbjct: 119 DILPNEAPCYISGWGRLYTGGPL-PDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG 177 Query: 202 WTGGKDTCGGDSGGPLVC---------NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 T + C GDSGGPL C +GV ++++G C +KP V+T+V + W Sbjct: 178 DT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFG---CNTIKKPTVFTRVSAFIDW 232 Query: 253 IKDTIAAN 260 I +TIA+N Sbjct: 233 IDETIASN 240 >1ZJK-A nrPDB Length = 403 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 79/260 (30%), Positives = 119/260 (45%), Gaps = 44/260 (16%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGR 77 +I GG + + PWQV + G G L++ WVLTAAH + + + +G Sbjct: 161 QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 218 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 P T ++ ++ H+ D +D+ L++L+ I + Sbjct: 219 LKRLSPHYT------------QAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNIT 266 Query: 138 VLGLPTQEPA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + LP +E +GT ASGWG + FL R+L V + ++ + C AY + Sbjct: 267 PICLPRKEAESFMRTDDIGT---ASGWG-LTQRGFL-ARNLMYVDIPIVDHQKCTAAYEK 321 Query: 191 ------KVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEPCALPE 238 VT MLCAGL +GGKD+C GDSGG LV + GI SWG C Sbjct: 322 PPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAG 381 Query: 239 KPAVYTKVVHYRKWIKDTIA 258 + VYTKV++Y WI++ I+ Sbjct: 382 QYGVYTKVINYIPWIENIIS 401 >4FXG-H nrPDB Length = 242 Score = 99.8 bits (247), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 118/259 (45%), Gaps = 44/259 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGRH 78 I GG + + PWQV + G G L++ WVLTAAH + + + +G Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 P T ++ ++ H+ D +D+ L++L+ I + Sbjct: 59 KRLSPHYT------------QAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 106 Query: 139 LGLPTQEPA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE- 190 + LP +E +GT ASGWG + FL R+L V + ++ + C AY + Sbjct: 107 ICLPRKEAESFMRTDDIGT---ASGWG-LTQRGFL-ARNLMYVDIPIVDHQKCTAAYEKP 161 Query: 191 -----KVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEPCALPEK 239 VT MLCAGL +GGKD+C GD+GG LV + GI SWG C + Sbjct: 162 PYPRGSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQ 221 Query: 240 PAVYTKVVHYRKWIKDTIA 258 VYTKV++Y WI++ I+ Sbjct: 222 YGVYTKVINYIPWIENIIS 240 >5XW8-A nrPDB Length = 133 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 12/138 (8%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+ C +S P+QV++ S G CGG L++ QWV++AAHC K QV LG HN+ Sbjct: 8 KIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q + + HP +N + L +D+ML++LS PA + V + LP Sbjct: 67 EGNEQFINAAKIITHPNFNGNTLD-----------NDIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 QEPALGTTCYASGWGSIE 161 A GT C SGWG+ + Sbjct: 116 SCAAAGTECLISGWGNTK 133 >1C5M-D nrPDB Length = 255 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 115/245 (46%), Gaps = 25/245 (10%) Query: 25 IVGGWECEKHSQPWQ-VAVYSHGWAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLF 81 IVGG EC+ PWQ + + CGG ++ ++LTAAHCL K +V +G N Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNT- 59 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E+ G+ V H + ++KH E D+ +LRL P V L Sbjct: 60 EQEEGGEAV-------HEV--EVVIKHNRF-TKETYDFDIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 P ++ A T T SG+G E+ + L+ + + + + C + S +T+ M Sbjct: 110 PERDWAESTLMTQKTGIVSGFGRTH-EKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 168 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG T +D C GDSGGP V + GI SWG E CA K +YTKV + KW Sbjct: 169 FCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKW 227 Query: 253 IKDTI 257 I ++ Sbjct: 228 IDRSM 232 >1KIG-H nrPDB Length = 241 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 109/248 (43%), Gaps = 25/248 (10%) Query: 25 IVGGWECEKHSQPWQ-VAVYSHGWAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLF 81 IVGG +C + PWQ + V CGG +++ +VLTAAHCL K V +G N Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E V + H + E D+ +LRL P + V L Sbjct: 61 QEEGNEMAHEVEMTVKHSRF-----------VKETYDFDIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 P ++ A T T SG+G + L +L+ + + + C + S +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGRTHEKGRLSS-TLKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG T +D C GDSGGP V + GI SWG E CA K VYTKV ++ KW Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTIAAN 260 I + A Sbjct: 228 IDKIMKAR 235 >1EQ9-A nrPDB Length = 222 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 79/236 (33%), Positives = 114/236 (48%), Gaps = 25/236 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS-----QVWLGRHN 79 IVGG + P+QV++ G CG ++ VLTAAHC+ S +V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L E +G V + + Y+ LL++ D+ L+ L+ P K D+V+ + Sbjct: 61 LSE---SGDVYDVEDAVVNKNYDDFLLRN-----------DVALVHLTNPIKFNDLVQPI 106 Query: 140 GLPTQEPALGTT-CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 L T + L + C +GWGS P +LQ + L + C R +V + +C Sbjct: 107 KLSTNDEDLESNPCTLTGWGSTRLGGNT-PNALQEIELIVHPQKQCERD-QWRVIDSHIC 164 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254 L G+ C GDSGGPLV NG GI S+G PCAL E P VYT+V + WI Sbjct: 165 T-LTKRGEGACHGDSGGPLVANGAQIGIVSFG-SPCALGE-PDVYTRVSSFVSWIN 217 >4KKD-A nrPDB Length = 433 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 124/282 (43%), Gaps = 57/282 (20%) Query: 17 AVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHC-------GGVLVHPQWVLTAAHCL-- 67 ++P + RI+GG E PWQ + + G L+ W+LTAAH L Sbjct: 147 SLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRS 206 Query: 68 -----------KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDED 116 K++ V+LG H++ + + + HP +N+ ++ Sbjct: 207 QRRDTTVIPVSKEHVTVYLGLHDVRD-KSGAVNSSAARVVLHPDFNI-----------QN 254 Query: 117 SSHDLMLLRLSEPAKITDVVKVLGLPTQEP---ALGTTCYASGWGSIEP----EEFLRPR 169 +HD+ L++L EP + V + LP EP A +GWG P +E + Sbjct: 255 YNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSG 314 Query: 170 S------LQCVSLHLLSNDMCARAYSEK-----VTEFMLCAGLWTGGKDTCGGDSGGPLV 218 + LQ V L ++ + C +Y + VTE M CAG + GGKDTC GDSG V Sbjct: 315 TRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFV 374 Query: 219 CNG------VLQGITSW-GPEPCALPEKPAVYTKVVHYRKWI 253 V+QG+ SW GPE C + VYTKV +Y W+ Sbjct: 375 IFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 416 >1PPF-E nrPDB Length = 218 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/239 (31%), Positives = 104/239 (43%), Gaps = 28/239 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVW----LGRHNL 80 IVGG H+ P+ V++ G CG L+ P +V++AAHC+ + LG HNL Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E T Q V F + ++LL +D+++L+L+ A I V+V Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 108 Query: 141 LPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 LP Q LG C A GWG + R R + V L N + + L Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLG-----RNRGIASVLQEL--NVTVVTSLCRRSNVCTLV 161 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G G C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 162 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 217 >4IW4-E nrPDB Length = 279 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 82/274 (29%), Positives = 120/274 (43%), Gaps = 57/274 (20%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHC-------GGVLVHPQWVLTAAHCL---------- 67 I+GG E PWQ + + G L+ W+LTAAH L Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 68 ---KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 K++ V+LG H++ + + + HP +N+ ++ +HD+ L+ Sbjct: 61 PVSKEHVTVYLGLHDVRD-KSGAVNSSAARVVLHPDFNI-----------QNYNHDIALV 108 Query: 125 RLSEPAKITDVVKVLGLPTQEP---ALGTTCYASGWGSIEP----EEFLRPRS------L 171 +L EP + V + LP EP A +GWG P +E + + L Sbjct: 109 QLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVL 168 Query: 172 QCVSLHLLSNDMCARAYSEK-----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----- 221 Q V L ++ + C +Y + VTE M CAG + GGKDTC GDSGG V Sbjct: 169 QYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQR 228 Query: 222 -VLQGITSW-GPEPCALPEKPAVYTKVVHYRKWI 253 V+QG+ SW GPE C + VYTKV +Y W+ Sbjct: 229 WVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 262 >1VR1-H nrPDB Length = 261 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/269 (28%), Positives = 118/269 (43%), Gaps = 47/269 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH------CGGVLVHPQWVLTAAHCL----------K 68 IV G + E PWQV +++ CG L+ +WVLTAAHCL + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 KNSQVWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V +G+H+ E +++ + + HP YN E+ D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPEEFL-----RPRSLQCVSLH 177 +P +D + + LP +E A G +GWG+++ +P LQ V+L Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 170 Query: 178 LLSNDMCARAYSEKVTEFMLCAGLW-TGGK--DTCGGDSGGPLVCNGVLQ------GITS 228 ++ +C + ++T+ M CA GK D C GDSGGP V GI S Sbjct: 171 IVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 231 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 258 >2XXL-A nrPDB Length = 408 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/269 (28%), Positives = 122/269 (45%), Gaps = 35/269 (13%) Query: 20 LIQSRIVGGWECEKHSQPWQVAVYSHGWAH----CGGVLVHPQWVLTAAHCLK--KNS-- 71 + R+ G+E + S+PW + + CGG ++ +++LTAAHC+ +N Sbjct: 114 FLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLY 173 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH---DLMLLRLSE 128 ++ LG H + ED Q+ P P+ N+ + KH + D+ H D+ LL+L+ Sbjct: 174 EIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHL-IHEKYDARHIMHDIALLKLNR 231 Query: 129 PAKITDVVKVLGLP-----TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183 +K + LP ++ +T + +GWG+ E L ++ L Sbjct: 232 SVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGS--SSDVLLQANVPLQPRSA 289 Query: 184 CARAYSEKVTEFMLCAGLWTGG--KDTCGGDSGGPLVC----------NGVLQGITSWGP 231 C++AY V LC G GG +D+C GDSGGPL V GI S G Sbjct: 290 CSQAYRRAVPLSQLCVG---GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGV 346 Query: 232 EPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 C P +YT V Y +WI DT+A+N Sbjct: 347 VTCGQISLPGLYTNVGEYVQWITDTMASN 375 >1SI5-H nrPDB Length = 240 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 36/235 (15%) Query: 38 WQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNLFEPEDTGQRVPVS 93 W V++ CGG L+ WVLTA C K+ + WLG H++ D + Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCK---- 68 Query: 94 HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL--GTT 151 + N+S L + DL+L++L+ PA + D V + LP + T+ Sbjct: 69 -----QVLNVSQLVYGP------EGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTS 117 Query: 152 CYASGWGS---IEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT--EFMLCAGLWTGGK 206 C GWG I + LR L+++ N+ C++ + KVT E +CAG G Sbjct: 118 CSVYGWGYTGLINYDGLLR-----VAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGS 172 Query: 207 DTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 C GD GGPLVC ++ G+ G CA+P +P ++ +V +Y KWI I Sbjct: 173 GPCEGDYGGPLVCEQHKMRMVLGVIVPG-RGCAIPNRPGIFVRVAYYAKWIHKII 226 >1YM0-A nrPDB Length = 238 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 123/253 (48%), Gaps = 32/253 (12%) Query: 25 IVGGWECEKHSQPWQVAVY--SHGWAHCGGVLVHPQWVLTAAHCLKKNS----QVWLGRH 78 IVGG E + PWQV+V S CGG +++ +WV+ AAHC++ + + +G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 + Q V F + Y+ + L+ +D+ +++ + IT + V Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLE-----------NDVSVIKTA--VAITFDINV 107 Query: 139 LGLPTQEPA---LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTE 194 + +PA + SGWG+I P L+ V+L++ +N C Y S+ + + Sbjct: 108 GPICAPDPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYD 167 Query: 195 FMLCAGLWTG--GKDTCGGDSGGPL-VCNG----VLQGITSWGPEPCALPEKPAVYTKVV 247 M+CA TG +D+C GDSGGPL V +G L GI SWG CA P VY++V Sbjct: 168 DMICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCA-SGYPGVYSRVG 225 Query: 248 HYRKWIKDTIAAN 260 + WI DTI N Sbjct: 226 FHAGWITDTITNN 238 >5TO3-B nrPDB Length = 409 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 116/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPEEFL-----RPRSLQCVSLHLLSN 181 +D + + LP +E A G +GWG+++ +P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 170 Query: 182 DMCARAYSEKVTEFMLCAGLWTG-GK--DTCGGDSGGPLVCNGVLQ------GITSWGPE 232 +C + ++T+ M CAG GK D C GDSGGP V GI S G Sbjct: 171 PVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAG 230 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V +KWI+ I Sbjct: 231 -CDRDGKYGFYTHVFRLKKWIQKVI 254 >2OLG-A nrPDB Length = 278 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 121/260 (46%), Gaps = 29/260 (11%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAH-----CGGVLVHPQWVLTAAHCLKKN------- 70 +I+ G + PW + ++ CGG L++ ++++TAAHC+ Sbjct: 21 DKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGA 80 Query: 71 -SQVWLGRHNL-FEPEDTGQRVPVSHSFPHPLYNMSLLKH-QSLRPDEDSSHDLMLLRLS 127 ++V LG N +P+ G P L ++H + +D HD+ L+RL+ Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLN 140 Query: 128 EPAKITDVVKVLGLP--TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 + T+ ++ + LP +E +G GWG E ++ + Q +++ ++ + CA Sbjct: 141 RQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK--QKLAVPVVHAEQCA 198 Query: 186 RAYSE---KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGV-----LQGITSWGPEPCALP 237 + + +V LCAG KD+CGGDSGGPL+ L+G+ S+G C Sbjct: 199 KTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGA-TCGTE 256 Query: 238 EKPAVYTKVVHYRKWIKDTI 257 P +YTKV YR WI+ I Sbjct: 257 GWPGIYTKVGKYRDWIEGNI 276 >4LK4-A nrPDB Length = 357 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 108/251 (43%), Gaps = 34/251 (13%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHGW-----AHCGGVLVHPQWVLTAAHCLKKNS---- 71 I SRI+ G P VA+ G CGG + ++VLTAAHC S Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G ++L G+R+ + H Y+ S L + + + L + L+ PA Sbjct: 67 DVIIGAYDL-NNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLAGPAT 125 Query: 132 ITDVVKVLGLPTQEPALGTTCYASGWG---SIEPEEFLRPRSLQCVSLHLLSNDMCA--- 185 T + PAL T +GWG +P +F LQ V + L+S +C Sbjct: 126 RTSL----------PAL-TPLTVAGWGITVQSKPPQFTPI--LQEVDVDLVSQSLCQIVM 172 Query: 186 -RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC-NGVLQ-GITSWGPEPCALPEKPAV 242 S CA T KD+C GD+GGP+V G Q GI SWG E CA V Sbjct: 173 QHGISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGV 230 Query: 243 YTKVVHYRKWI 253 YT V ++R WI Sbjct: 231 YTNVSYFRDWI 241 >5UBM-A nrPDB Length = 252 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 78/260 (30%), Positives = 116/260 (44%), Gaps = 37/260 (14%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ--VWLGRHNLF 81 RI+GG + + + PWQV + + WA GG L++ WVLTAAH ++ N + +++G ++ Sbjct: 1 RIIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 82 EPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 ++ H F HP + LL+ R + D +D+ L+RL +P K+ V + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGW--KLLEVPEGRTNFD--NDIALVRLKDPVKMGPTVSPIC 113 Query: 141 LPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK----- 191 LP G SGWG E + R L+ L + C EK Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 ----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPEKP 240 T M+CAG G D+C GDSGG G+ SWGP+ C Sbjct: 172 EAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 241 AVYTKVVHYRKWIKDTIAAN 260 +YT+V +Y WI T+ N Sbjct: 227 GLYTRVKNYVDWIMKTMQEN 246 >1ELV-A nrPDB Length = 333 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 75/262 (28%), Positives = 114/262 (43%), Gaps = 37/262 (14%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ--VWLGRHN 79 + RI+GG + + + PWQV + + WA GG L++ WVLTAAH ++ N + +++G + Sbjct: 80 KQRIIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGNREPTMYVGSTS 136 Query: 80 LFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 + ++ H F HP + + + D +D+ L+RL +P K+ V Sbjct: 137 VQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFD----NDIALVRLKDPVKMGPTVSP 192 Query: 139 LGLPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK--- 191 + LP G SGWG E + R L+ L + C EK Sbjct: 193 ICLPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRKCKEVKVEKPTA 250 Query: 192 ------VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPE 238 T M+CAG G D+C GDSGG G+ SWGP+ C Sbjct: 251 DAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT-- 306 Query: 239 KPAVYTKVVHYRKWIKDTIAAN 260 +YT+V +Y WI T+ N Sbjct: 307 -YGLYTRVKNYVDWIMKTMQEN 327 >4J1Y-A nrPDB Length = 397 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 77/262 (29%), Positives = 117/262 (44%), Gaps = 37/262 (14%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ--VWLGRHN 79 ++R +GG + + + PWQV + + WA GG L++ WVLTAAH ++ N + +++G + Sbjct: 144 KARAIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGNREPTMYVGSTS 200 Query: 80 LFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 + ++ H F HP + LL+ R + D +D+ L+RL +P K+ V Sbjct: 201 VQTSRLAKSKMLTPEHVFIHPGW--KLLEVPEGRTNFD--NDIALVRLKDPVKMGPTVSP 256 Query: 139 LGLPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK--- 191 + LP G SGWG E + R L+ L + C EK Sbjct: 257 ICLPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRKCKEVKVEKPTA 314 Query: 192 ------VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPE 238 T M+CAG G D+C GDSGG G+ SWGP+ C Sbjct: 315 DAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT-- 370 Query: 239 KPAVYTKVVHYRKWIKDTIAAN 260 +YT+V +Y WI T+ N Sbjct: 371 -YGLYTRVKNYVDWIMKTMQEN 391 >2B9L-A nrPDB Length = 394 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 74/257 (28%), Positives = 102/257 (39%), Gaps = 35/257 (13%) Query: 30 ECEKHSQPWQVAVYSHG--------WAHCGGVLVHPQWVLTAAHCL---KKNSQVWLGRH 78 E E PW VAV CGG L+ P VLT AHC+ + N R Sbjct: 136 EAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRA 195 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 ++ +R+P ++ H + P + +D+ LL L P D + Sbjct: 196 GEWDTLTEKERLPYQERKIR-----QVIIHSNFNP-KTVVNDVALLLLDRPLVQADNIGT 249 Query: 139 LGLPTQEPALGTT-CYASGWGSIEPEEFLRPRS-LQCVSLHLLSNDMCARAYSEK----- 191 + LP Q +T C+ASGWG E R + L+ + L + D C Sbjct: 250 ICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLK 309 Query: 192 --VTEFMLCAGLWTGGKDTCGGDSGGPLVC-------NGVLQGITSWGPEPCALPEKPAV 242 + + +CAG GKDTC GD G PL C + GI +WG C P V Sbjct: 310 FVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI-GCGDENVPGV 367 Query: 243 YTKVVHYRKWIKDTIAA 259 Y V H+R WI + A Sbjct: 368 YANVAHFRNWIDQEMQA 384 >4BXW-A nrPDB Length = 423 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 110/249 (44%), Gaps = 29/249 (11%) Query: 24 RIVGGWECEKHSQPWQVA-VYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 RIV G +C+ PWQ A V CGG ++ P +VLTAAHC+ + + + + + Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 83 PE-DTG-----QRVPVSHSF--PHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITD 134 +TG ++ V F P Y L + +D+ ++++ P + ++ Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYD---------YDIAIIQMKTPIQFSE 279 Query: 135 VVKVLGLPTQEPALGTTC-----YASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS 189 V LPT + A SG+G I E+ + ++L+ + + + C + Sbjct: 280 NVVPACLPTADFANQVLMKQDFGIVSGFGRI-VEKGPKSKTLKVLKVPYVDRHTCMVSSE 338 Query: 190 EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTK 245 +T M CAG T +D C GDSGGP + GI S G E CA K YTK Sbjct: 339 TPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG-EGCARNGKYGNYTK 397 Query: 246 VVHYRKWIK 254 + + WIK Sbjct: 398 LSKFIPWIK 406 >6BQM-A nrPDB Length = 506 Score = 80.9 bits (198), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 72/264 (27%), Positives = 112/264 (42%), Gaps = 39/264 (14%) Query: 15 TGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLKKNS- 71 +G + SRI+GG + P+ VA+ + +H CGG + ++VLTAAHC+ K Sbjct: 1 SGTESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDP 60 Query: 72 ---QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE 128 V LG ++ + +T +R+ V + H Y + + +D+ +L L Sbjct: 61 AKGDVLLGAFDMNDV-NTAERIHVRQIYVHNSYITASM-----------GNDIAVLELER 108 Query: 129 ------PAKITDVVKVLGLPTQEP----ALGTTCYASGWGSIEPEEFLRPRSLQCVSL-- 176 +I+D L P G G S +P L + V L Sbjct: 109 DPLPRRSVQISDSSDFNELTKDSPMTVIGFGNRKEVDGEKS-DPATILHQVQVPFVPLPE 167 Query: 177 -HLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ-GITSWGP 231 +D A+ ++T CAG + GKD C GD+GGP+ NG Q G+ SWG Sbjct: 168 CKTKGSDQDAKNNYSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWG- 224 Query: 232 EPCALPEKPAVYTKVVHYRKWIKD 255 + C P VYT + + W+ D Sbjct: 225 DGCGRANSPGVYTNLSVFNDWLDD 248 >1MD7-A nrPDB Length = 328 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 74/257 (28%), Positives = 109/257 (42%), Gaps = 37/257 (14%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL---------KKNSQ 72 + RI+GG + + + PWQV HG GG L+ +W+LTAAH L + Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH--DLMLLRLSEPA 130 V+LG N+ E G HP+ +S+ H R DE + D+ LL L Sbjct: 145 VFLGHTNVEELMKLGN---------HPIRRVSV--HPDYRQDESYNFEGDIALLELENSV 193 Query: 131 KITDVVKVLGLPTQEP--ALGTTCYASGWGSIEPE--EFLRPRSLQCVSLHLLSNDMCAR 186 + + + LP + LG Y SG+G +E + LR L + N + + Sbjct: 194 TLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGK 253 Query: 187 AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKP 240 + ++ M CAG + +D C GD+GG V GI SWG Sbjct: 254 NRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWG---IGCSRGY 310 Query: 241 AVYTKVVHYRKWIKDTI 257 YTKV++Y WIK + Sbjct: 311 GFYTKVLNYVDWIKKEM 327 >4X0L-C nrPDB Length = 259 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 111/274 (40%), Gaps = 65/274 (23%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ----------- 72 RI+GG K S PWQ + SH G L++ QW+LT A L N Sbjct: 14 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 73 Query: 73 --VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130 +++G+ L E E HP Y S D+ L++L + Sbjct: 74 LTLYVGKKQLVEIEKV---------VLHPNY---------------SQVDIGLIKLKQKV 109 Query: 131 KITDVVKVLGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS 189 + + V + LP+++ A +G Y SGWG F L+ V L + D C R Y Sbjct: 110 SVNERVMPICLPSKDYAEVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHYE 167 Query: 190 -----EKVT------------EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQ------GI 226 EK T E CAG+ +DTC GD+G + + + GI Sbjct: 168 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 227 Query: 227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 S+ + CA+ E VY KV + W++ TIA N Sbjct: 228 LSFD-KSCAVAEY-GVYVKVTSIQDWVQKTIAEN 259 >2QY0-B nrPDB Length = 242 Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 107/254 (42%), Gaps = 37/254 (14%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL---------KKNSQVWL 75 I+GG + + + PWQV HG GG L+ +W+LTAAH L + V+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHG--RGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH--DLMLLRLSEPAKIT 133 G N+ E G HP+ +S+ H R DE + D+ LL L + Sbjct: 59 GHTNVEELMKLGN---------HPIRRVSV--HPDYRQDESYNFEGDIALLELENSVTLG 107 Query: 134 DVVKVLGLPTQEP--ALGTTCYASGWGSIEPE--EFLRPRSLQCVSLHLLSNDMCARAYS 189 + + LP + LG Y SG+G +E + LR L + N + + Sbjct: 108 PNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRM 167 Query: 190 EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAVY 243 + ++ M CAG + +D C GDSGG V GI SWG Y Sbjct: 168 DVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFY 224 Query: 244 TKVVHYRKWIKDTI 257 TKV++Y WIK + Sbjct: 225 TKVLNYVDWIKKEM 238 >4WJG-C nrPDB Length = 315 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 111/274 (40%), Gaps = 65/274 (23%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ----------- 72 RI+GG K S PWQ + SH G L++ QW+LT A L N Sbjct: 70 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 129 Query: 73 --VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130 +++G+ L E E HP Y S D+ L++L + Sbjct: 130 LTLYVGKKQLVEIEKV---------VLHPNY---------------SQVDIGLIKLKQKV 165 Query: 131 KITDVVKVLGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS 189 + + V + LP+++ A +G Y SGWG F L+ V L + D C R Y Sbjct: 166 SVNERVMPICLPSKDYAEVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHYE 223 Query: 190 -----EKVT------------EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQ------GI 226 EK T E CAG+ +DTC GD+G + + + GI Sbjct: 224 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 283 Query: 227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 S+ + CA+ E VY KV + W++ TIA N Sbjct: 284 LSFD-KSCAVAEY-GVYVKVTSIQDWVQKTIAEN 315 >2ASU-B nrPDB Length = 234 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 72/240 (30%), Positives = 101/240 (42%), Gaps = 39/240 (16%) Query: 35 SQPWQVAVYSHGWAH-CGGVLVHPQWVLTAAHCLKK------NSQVWLGRHNLFEPEDTG 87 + PW V++ + H CGG LV QW+LTA C +VWLG LF+ G Sbjct: 8 NSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLG--TLFQNPQHG 65 Query: 88 ----QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 QRVPV+ P S L+LL+L + V ++ LP Sbjct: 66 EPSLQRVPVAKMVCGP-----------------SGSQLVLLKLERSVTLNQRVALICLPP 108 Query: 144 QEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 + + GT C +GWG E + L L+++SN C + +V E +C Sbjct: 109 EWYVVPPGTKCEIAGWG--ETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEG 166 Query: 202 WTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 C GD GGPL C + VL+GI CA PAV+T+V + WI + Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIII-PNRVCARSRWPAVFTRVSVFVDWIHKVM 225 >1GPZ-A nrPDB Length = 399 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 111/257 (43%), Gaps = 37/257 (14%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-------KKNS--Q 72 + +I+GG + + + PWQV HG GG L+ +W+LTAAH L + N+ Sbjct: 155 RQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 212 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH--DLMLLRLSEPA 130 V+LG N+ E G HP+ +S+ H R DE + D+ LL L Sbjct: 213 VFLGHTNVEELMKLGN---------HPIRRVSV--HPDYRQDESYNFEGDIALLELENSV 261 Query: 131 KITDVVKVLGLPTQEP--ALGTTCYASGWGSIEPE--EFLRPRSLQCVSLHLLSNDMCAR 186 + + + LP + LG Y SG+G +E + LR L + N + + Sbjct: 262 TLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGK 321 Query: 187 AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKP 240 + ++ M CAG + +D C GDSGG V GI SWG Sbjct: 322 NRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGY 378 Query: 241 AVYTKVVHYRKWIKDTI 257 YTKV++Y WIK + Sbjct: 379 GFYTKVLNYVDWIKKEM 395 >2FMJ-A nrPDB Length = 222 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 106/241 (43%), Gaps = 38/241 (15%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG + P+ V + S G CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRL-SMG---CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 TG V + S + + +L+ + D L++L++P + PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQAPGY---NGTGKDWALIKLAQP---------INQPTL 97 Query: 145 EPALGTTCY------ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFML 197 + A TT Y +GWG+ E + R L ++ +S+ C AY +E V + Sbjct: 98 KIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEI 155 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG TGG DTC GDSGGP+ + GI SWG E CA K VYT+V + Sbjct: 156 CAGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-EGCARKGKYGVYTEVSTFASA 214 Query: 253 I 253 I Sbjct: 215 I 215 >3RU4-E nrPDB Length = 96 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 44/97 (45%), Positives = 55/97 (56%), Gaps = 7/97 (7%) Query: 168 PRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NG--VL 223 P LQ SL LLSN C + + K+ + M+CAG G +C GDSGGPLVC NG L Sbjct: 3 PDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWTL 60 Query: 224 QGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GI SWG C+ P VY +V W++ T+AAN Sbjct: 61 VGIVSWGSSTCS-TSTPGVYARVTALVNWVQQTLAAN 96 >4F4O-C nrPDB Length = 347 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 108/271 (39%), Gaps = 59/271 (21%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 RI+GG K S PWQ + SH G L++ QW+LT A L+ LG N + Sbjct: 102 RIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLR------LGHKNDTKA 155 Query: 84 EDTG----------QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 +D Q V + HP ++S+ D+ L++L + + Sbjct: 156 KDIAPTLRLYVGKKQEVEIEKVIFHP---------------DNSTVDIGLIKLKQKVPVN 200 Query: 134 DVVKVLGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS--- 189 + V + LP+++ +G Y SGWG F L+ V L + + C + Y Sbjct: 201 ERVMPICLPSKDYVNVGLVGYVSGWGRNANLNFT--EHLKYVMLPVADQEKCVQYYEGST 258 Query: 190 --EKVT------------EFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSW 229 EK T E CAGL +DTC GD+G + GI S+ Sbjct: 259 VPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSF 318 Query: 230 GPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 + C E VY +V WI+ TIA N Sbjct: 319 D-KSCRTAEY-GVYVRVTSILDWIQTTIADN 347 >2HLC-A nrPDB Length = 230 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 104/242 (42%), Gaps = 31/242 (12%) Query: 25 IVGGWECEKHSQPWQ----VAVYSHGWAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRH 78 I+ G+E P+Q + + CGG L+ +W+LTAAHC+ + V+LG Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 +E G+ V S ++ H PD +D+ L+++ + TD ++ Sbjct: 61 VQYE----GEAVVNSER---------IISHSMFNPDT-YLNDVALIKIPH-VEYTDNIQP 105 Query: 139 LGLPTQEPALGTT----CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE 194 + LP+ E SGWG + + LQ ++ ND CA+ Y + Sbjct: 106 IRLPSGEELNNKFENIWATVSGWGQSNTDTVI----LQYTYNLVIDNDRCAQEYPPGIIV 161 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCN--GVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 G + GK C GDSGGP V + +L G+ S+ KP +++V Y W Sbjct: 162 ESTICGDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDW 221 Query: 253 IK 254 I+ Sbjct: 222 IQ 223 >2JET-B nrPDB Length = 128 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 15/131 (11%) Query: 35 SQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWL-GRHNLFEPEDTGQRVPV 92 S PWQV++ G+ CGG L+ WV+TAAHC K S V + G + E+ Q + + Sbjct: 8 SWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEENIQVLKI 67 Query: 93 SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL--GT 150 + F +P +NM ++ +D+ LL+L+ PA+ ++ V + LP + GT Sbjct: 68 AQVFKNPKFNMFTVR-----------NDITLLKLATPAQFSETVSAVCLPNVDDDFPPGT 116 Query: 151 TCYASGWGSIE 161 C +GWG + Sbjct: 117 VCATTGWGKTK 127 >1M9U-A nrPDB Length = 241 Score = 72.0 bits (175), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 107/254 (42%), Gaps = 36/254 (14%) Query: 25 IVGGWECEKHSQPWQVAVY--SHGWAH-CGGVLVHPQWVLTAAHC----LKKNSQVWLGR 77 ++GG PWQ++ S W+H CG L+ L+A+HC L N +V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG- 59 Query: 78 HNLFEPEDTG--QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 L++ DT Q V H Y + S+D+ +L L+ + Sbjct: 60 --LWQQSDTSGTQTANVDSYTMHENYGAGTASY---------SNDIAILHLATSISLGGN 108 Query: 136 VKVLGLP--TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY----S 189 ++ LP GTTC SGWG + L P LQ S+ +++ C A Sbjct: 109 IQAAVLPANNNNDYAGTTCVISGWGRTDGTNNL-PDILQKSSIPVITTAQCTAAMVGVGG 167 Query: 190 EKVTEFMLCAGLWTGGKDTCGGDSGGPLVC---NGVLQGITSW----GPEPCALPEKPAV 242 + + +C G C GDSGGPL C + G+TSW G C LP+ P+V Sbjct: 168 ANIWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSV 226 Query: 243 YTKVVHYRKWIKDT 256 YT+V Y WI D Sbjct: 227 YTRVSAYLGWIGDN 240 >3I77-A nrPDB Length = 230 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 103/243 (42%), Gaps = 34/243 (13%) Query: 25 IVGGWECEKHSQPWQVA-VYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +VGG + P+ V + CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVS-------GSGNNTSI 53 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 TG V + S + + +L+ E D L++L++P + PT Sbjct: 54 TATGGVVDLQSSSAVKVRSTKVLQAPGF-TKETYGKDWALIKLAQP---------INQPT 103 Query: 144 QEPALGTTCY------ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFM 196 + A TT Y +GWG+ E + R L ++ +S+ C + S V M Sbjct: 104 LKIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEM 161 Query: 197 LCAGL-WTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYR 250 +CAG TGG DTC GDSGGP+ + GI SWG CA P P VYT+V + Sbjct: 162 ICAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFA 220 Query: 251 KWI 253 I Sbjct: 221 SAI 223 >3VGC-B nrPDB Length = 131 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 15/138 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWL-GRHNLFE 82 IV G E S PWQV++ G+ CGG L++ WV+TAAHC S V + G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 + Q++ ++ F + YN + ++D+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTI-----------NNDITLLKLSTAASFSQTVSAVCLP 109 Query: 143 --TQEPALGTTCYASGWG 158 + + A GTTC +GWG Sbjct: 110 SASDDFAAGTTCVTTGWG 127 >2JET-C nrPDB Length = 99 Score = 70.1 bits (170), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 40/97 (41%), Positives = 56/97 (57%), Gaps = 7/97 (7%) Query: 168 PRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGV--L 223 P LQ +L ++S C +++ K+T+ M CAG G D+C GDSGGPLVC +GV L Sbjct: 6 PEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKDGVWTL 63 Query: 224 QGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GI SWG C+ P VY++V W++ + AN Sbjct: 64 AGIVSWGSGVCST-STPGVYSRVTALMPWVQQILEAN 99 >3H7O-A nrPDB Length = 228 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 112/245 (45%), Gaps = 35/245 (14%) Query: 27 GGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLF 81 GG + + PW VAV ++ CGG ++ +VLTAAHC+ +K + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 82 EPEDTGQRVP-VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV-VKVL 139 ED G+ P VSH + +S + +++ +D+ +L LS P K+ + K Sbjct: 62 LWEDPGKSDPYVSHVY------LSFYRQETME------NDIAILELSRPLKLDGLKSKPA 109 Query: 140 GLPTQE--PALGTTCYASGWG---SIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE 194 LP E P G+ SG+G +++P++ L+ L ++ D C Y Sbjct: 110 KLPDIEFRPKTGSDVLVSGYGDGQTMDPKD----HDLKSAQLTVVDLDECRTKYGPIFLS 165 Query: 195 F-MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPE-KPAVYTKVVHYRKW 252 + CA G GD+G P V L G+ ++ P+ PE P V+TKV Y W Sbjct: 166 LQVFCA--QKVGVSLESGDAGDPTVQQDTLVGVAAYFPK---RPEGAPEVFTKVGSYVSW 220 Query: 253 IKDTI 257 I+D I Sbjct: 221 IQDII 225 >3BEU-A nrPDB Length = 224 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 75/241 (31%), Positives = 104/241 (43%), Gaps = 36/241 (14%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG + P+ V + S G CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRL-SMG---CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 TG V + S + + +L+ E D L++L++P + PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQAPGF-TKETYGKDWALIKLAQP---------INQPTL 99 Query: 145 EPALGTTCY------ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFML 197 + A TT Y +GWG+ E + R L ++ +S+ C + S V M+ Sbjct: 100 KIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMI 157 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG T +DTC GDSGGP+ V GI SWG E CA K VYT+V + Sbjct: 158 CAGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWG-EGCARKGKYGVYTEVSTFASA 216 Query: 253 I 253 I Sbjct: 217 I 217 >3H7T-A nrPDB Length = 235 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 56/245 (22%), Positives = 101/245 (41%), Gaps = 23/245 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GG + + +PW V V CGG ++ +V+TAA C+ + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIH------ 54 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITD-VVKVLGLPT 143 G + + ++++ L ++ ++ P K+ D K + LP+ Sbjct: 55 -YGSSYRTTKGTSVMAKKIYIVRYHPLT----MQNNYAVIETEMPIKLDDKTTKKIELPS 109 Query: 144 --QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 +P T+ SGWGS + L + ++ C Y + + + G+ Sbjct: 110 LLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGV 169 Query: 202 WTGGKD-----TCGGDSGGPLVCNGVLQGITSWGPEPCALP-EKPAVYTKVVHYRKWIKD 255 + G + GD+G P V NG L G+ S+ ++P E P+V+ +V +Y IKD Sbjct: 170 FCAGGEYDETYIGYGDAGDPAVQNGTLVGVASY---ISSMPSEFPSVFLRVGYYVLDIKD 226 Query: 256 TIAAN 260 I+ Sbjct: 227 IISGK 231 >1RIW-B nrPDB Length = 147 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 28/155 (18%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPVSHS-FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIE 161 +D + + LP +E A G +GWG+++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLK 145 >1BBR-E nrPDB Length = 109 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 10/101 (9%) Query: 166 LRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG-GK--DTCGGDSGGPLVCNG- 221 ++P LQ V+L L+ +C + ++T+ M CAG G GK D C GDSGGP V Sbjct: 5 VQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 222 -----VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 GI SWG E C K YT V +KWI+ I Sbjct: 65 YNNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 104 >2I6S-A nrPDB Length = 517 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 60/241 (24%), Positives = 99/241 (41%), Gaps = 47/241 (19%) Query: 32 EKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDT-GQRV 90 ++ PW V + C G L+ QWVLTAAHC + + L R N+ +P+ G+ Sbjct: 239 DQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEF 298 Query: 91 PVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP-TQEPAL- 148 + + P +++ K+Q + E D+ LL+L++ K++ + + LP T E L Sbjct: 299 LIEKAVISPGFDVFAKKNQGIL--EFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLA 356 Query: 149 -----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM------------CARAYSEK 191 G+TC E L +S+ + L + + CA S++ Sbjct: 357 LRRPQGSTCRD------HENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQE 410 Query: 192 VTEF-------------MLCAGLWTGGKDTCGGDSGGPLVCNGVLQ----GITSWG-PEP 233 T F LC+G + C G+SGG + + G+ SWG P Sbjct: 411 KTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVGLVSWGLYNP 469 Query: 234 C 234 C Sbjct: 470 C 470 >1BBR-H nrPDB Length = 150 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 28/153 (18%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL-----KKNSQ----- 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL KN Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVP-VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ LL+L P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGS 159 ++D + + LP ++ A G +GWG+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGN 143 >2HNT-F nrPDB Length = 105 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 37/100 (37%), Positives = 48/100 (48%), Gaps = 10/100 (10%) Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW-TGGK--DTCGGDSGGPLVCNGVL 223 +P LQ V+L ++ +C + ++T+ M CAG GK D C GDSGGP V Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 224 Q------GITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 GI SWG E C K YT V +KWI+ I Sbjct: 62 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 100 >2WIN-I nrPDB Length = 507 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 99/251 (39%), Gaps = 61/251 (24%) Query: 29 WECEK----HSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 WE K H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 223 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSI 278 Query: 81 FEPEDTGQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 +R + + HP YN++ K + E +D+ L++L K ++ + Sbjct: 279 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPI 336 Query: 140 GLPTQEPAL-------GTTCYASGWGSIEPEEFLRPRSLQCV------------SLHLLS 180 LP E TTC + EE L + ++ + +++ + Sbjct: 337 CLPCTEGTTRALRLPPTTTCQQ------QKEELLPAQDIKALFVSEEEKKLTRKEVYIKN 390 Query: 181 NDM---CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG-- 221 D C R SE VT LC G + D TC GDSGGPL+ + Sbjct: 391 GDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 450 Query: 222 --VLQGITSWG 230 + G+ SWG Sbjct: 451 RFIQVGVISWG 461 >2OK5-A nrPDB Length = 752 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 99/251 (39%), Gaps = 61/251 (24%) Query: 29 WECEK----HSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 WE K H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 467 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSI 522 Query: 81 FEPEDTGQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 +R + + HP YN++ K + E +D+ L++L K ++ + Sbjct: 523 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPI 580 Query: 140 GLPTQEPAL-------GTTCYASGWGSIEPEEFLRPRSLQCV------------SLHLLS 180 LP E TTC + EE L + ++ + +++ + Sbjct: 581 CLPCTEGTTRALRLPPTTTCQQ------QKEELLPAQDIKALFVSEEEKKLTRKEVYIKN 634 Query: 181 NDM---CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG-- 221 D C R SE VT LC G + D TC GDSGGPL+ + Sbjct: 635 GDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 694 Query: 222 --VLQGITSWG 230 + G+ SWG Sbjct: 695 RFIQVGVISWG 705 >1DLE-A nrPDB Length = 298 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 99/251 (39%), Gaps = 61/251 (24%) Query: 29 WECEK----HSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 WE K H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 16 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSI 71 Query: 81 FEPEDTGQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 +R + + HP YN++ K + E +D+ L++L K ++ + Sbjct: 72 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPI 129 Query: 140 GLPTQEPAL-------GTTCYASGWGSIEPEEFLRPRSLQCV------------SLHLLS 180 LP E TTC + EE L + ++ + +++ + Sbjct: 130 CLPCTEGTTRALRLPPTTTCQQ------QKEELLPAQDIKALFVSEEEKKLTRKEVYIKN 183 Query: 181 NDM---CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG-- 221 D C R SE VT LC G + D TC GDSGGPL+ + Sbjct: 184 GDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 243 Query: 222 --VLQGITSWG 230 + G+ SWG Sbjct: 244 RFIQVGVISWG 254 >1EPT-B nrPDB Length = 82 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 11/90 (12%) Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 QV LG HN+ E Q + + HP +N + L +D+ML++LS PA Sbjct: 4 QVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSSPAT 52 Query: 132 ITDVVKVLGLPTQEPALGTTCYASGWGSIE 161 + V + LP A GT C SGWG+ + Sbjct: 53 LNSRVATVSLPRSCAAAGTECLISGWGNTK 82 >2HNT-C nrPDB Length = 70 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCL 67 IV G + E PWQV ++ CG L+ +WVLTAAHCL Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL 45 >3F1S-B nrPDB Length = 283 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 61/242 (25%), Positives = 83/242 (34%), Gaps = 48/242 (19%) Query: 37 PWQVAVY-SHGWAHCGGVLVHPQWVLTAAHC--LKKNSQVWLGRHNLFEPEDTGQRVPVS 93 PWQV + S G CGGV++ +VLT A C L +N V + + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---------------KTYFN 109 Query: 94 HSFPHPLYNMSLLKHQSLRPDEDS-SHDLMLLRLSEPAKITDVVKVLGLPTQEPALG--- 149 + PL H +R D D+ +DL LL L P + GLP P Sbjct: 110 RTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGA----GLPVCTPEKDFAE 165 Query: 150 ------TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC----- 198 T SGW + SL + L+ + C + + VT C Sbjct: 166 HLLIPRTRGLLSGWARNGTD---LGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSV 222 Query: 199 -AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 A W G + G GVL G +P + TKV Y W K + Sbjct: 223 AAMHWMDGS-VVTREHRGSWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 Query: 258 AA 259 A Sbjct: 276 NA 277 >3H5C-B nrPDB Length = 317 Score = 33.9 bits (76), Expect = 0.079, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 19/99 (19%) Query: 37 PWQVAVY-SHGWAHCGGVLVHPQWVLTAAHC--LKKNSQVWLGRHNLFEPEDTGQRVPVS 93 PWQV + S G CGGV++ +VLT A C L +N V + + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---------------KTYFN 150 Query: 94 HSFPHPLYNMSLLKHQSLRPDEDS-SHDLMLLRLSEPAK 131 + PL H +R D D+ +DL LL L P + Sbjct: 151 RTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQ 189 >6BPF-A nrPDB Length = 265 Score = 32.0 bits (71), Expect = 0.28, Method: Compositional matrix adjust. Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 23/141 (16%) Query: 91 PVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG-----LPTQE 145 P++ F L +L+ ++++ +L+L +L P K+T + +G L E Sbjct: 84 PITERFVGKSMTFDELSAATLQYSDNAAMNLILAKLGGPQKVTAFARSIGDDKFRLDRNE 143 Query: 146 PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM--------- 196 P+L T + + PR++ L D + EK++ ++ Sbjct: 144 PSLNTAIPG------DLRDTSTPRAMALSLQKLALGDALGQVQREKLSHWLRGNTTGAAS 197 Query: 197 LCAGL---WTGGKDTCGGDSG 214 + AGL W+ G T GD G Sbjct: 198 IRAGLPSGWSVGDKTGSGDYG 218 >1G0D-A nrPDB Length = 695 Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 34/82 (41%) Query: 15 TGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVW 74 TG+VP++Q G K+ Q W A + C G+ P +AH + N V Sbjct: 250 TGSVPILQQWSKAGVRPVKYGQCWVFAAVACTVLRCLGIPTRPITNFASAHDVDGNLSVD 309 Query: 75 LGRHNLFEPEDTGQRVPVSHSF 96 + E D+ QR S +F Sbjct: 310 FLLNERLESLDSRQRSDSSWNF 331 >1P3E-A nrPDB Length = 215 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 37 PWQ-VAVYSHGWAHCGGVLVHPQWVLTAAHCL 67 P+ +A + G + C G L+ P +LT HC+ Sbjct: 18 PYNSIAYITFGGSSCTGTLIAPNKILTNGHCV 49 >5VC2-A nrPDB Length = 424 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 29/72 (40%) Query: 175 SLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPC 234 S HLL D + YS K + L T K+T G++ P V +G+ G + Sbjct: 318 SNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRSPFVTSGIRIGSAALSARGM 377 Query: 235 ALPEKPAVYTKV 246 E + K+ Sbjct: 378 GAKEFEIIGNKI 389 >5KMU-A nrPDB Length = 290 Score = 27.7 bits (60), Expect = 4.8, Method: Compositional matrix adjust. Identities = 37/174 (21%), Positives = 71/174 (40%), Gaps = 25/174 (14%) Query: 60 VLTAAHCLKKN--SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDS 117 V+ AA LK++ + L + +P D P++ + ++ L +L+ +++ Sbjct: 76 VMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNT 135 Query: 118 SHDLMLLRLSEPAKITDVVKVLGLPTQ-----EPALGTTCYASGWGSIEPEEFLRPRSL- 171 + + ++ +L P +T + +G T EP L T +P + PR++ Sbjct: 136 AMNKLIAQLGGPGGVTAFARAIGDETFRLDRWEPTLNTAIPG------DPRDTTTPRAMA 189 Query: 172 QCVSLHLLSNDMCARAYSEKVT--------EFMLCAGL---WTGGKDTCGGDSG 214 Q + L + + ++ VT + AGL WT G T GD G Sbjct: 190 QTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYG 243 >3LCV-B nrPDB Length = 281 Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 6/49 (12%) Query: 113 PDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIE 161 P + DL+ RL EPA +T ++K L P L T SGW I+ Sbjct: 182 PHRTNVADLLEDRLDEPADVTLLLKTL------PCLETQQRGSGWEVID 224 >3ARQ-A nrPDB Length = 584 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRS 170 G+P + LGT Y GW + P+ P Sbjct: 427 GVPANKLVLGTAMYGRGWEGVTPDTLTDPND 457 >2PFE-A nrPDB Length = 186 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 15/25 (60%) Query: 210 GGDSGGPLVCNGVLQGITSWGPEPC 234 GGDSGGP + QG+TS G C Sbjct: 137 GGDSGGPWLTGSQAQGVTSGGTGDC 161 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4NFE-A nrPDB 379 e-106 3QUM-P nrPDB 350 3e-97 1SGF-G nrPDB 347 3e-96 1SPJ-A nrPDB 344 2e-95 1F7Z-A nrPDB 329 6e-91 1SGF-A nrPDB 328 1e-90 4AN7-A nrPDB 327 2e-90 4WWY-A nrPDB 327 4e-90 5C67-A nrPDB 324 3e-89 5FXL-A nrPDB 322 1e-88 1A0J-A nrPDB 321 2e-88 1AO5-A nrPDB 319 7e-88 1TON-A nrPDB 319 1e-87 1UTJ-A nrPDB 316 7e-87 1GVZ-A nrPDB 309 9e-85 1NPM-A nrPDB 305 9e-84 1FXY-A nrPDB 305 1e-83 5MS3-A nrPDB 304 2e-83 2TLD-E nrPDB 298 2e-81 2PSX-A nrPDB 292 8e-80 3BSQ-A nrPDB 292 9e-80 2EEK-A nrPDB 292 1e-79 6QHB-A nrPDB 289 1e-78 5ZFH-A nrPDB 287 3e-78 4GSO-A nrPDB 287 4e-78 1EUF-A nrPDB 281 2e-76 2AIQ-A nrPDB 280 4e-76 4E7N-A nrPDB 279 1e-75 5TJX-A nrPDB 275 2e-74 3T2N-A nrPDB 274 2e-74 6I44-A nrPDB 274 2e-74 1FI8-A nrPDB 274 3e-74 3LC3-A nrPDB 273 4e-74 1X7A-C nrPDB 273 6e-74 2CGA-A nrPDB 272 1e-73 1OP0-A nrPDB 271 2e-73 2F83-A nrPDB 270 4e-73 1BQY-A nrPDB 269 1e-72 5UGG-A nrPDB 269 1e-72 3S69-A nrPDB 269 1e-72 4DUR-A nrPDB 268 2e-72 2BDH-A nrPDB 267 3e-72 3K65-B nrPDB 267 4e-72 5GVT-A nrPDB 267 5e-72 3S9B-A nrPDB 266 7e-72 5LPF-A nrPDB 266 8e-72 3NXP-A nrPDB 266 8e-72 1MKW-K nrPDB 265 2e-71 1BRU-P nrPDB 265 2e-71 4NZQ-A nrPDB 264 2e-71 1KIG-H nrPDB 264 3e-71 1IAU-A nrPDB 263 6e-71 1P57-B nrPDB 262 9e-71 3E0N-B nrPDB 262 1e-70 3W94-A nrPDB 262 1e-70 1NN6-A nrPDB 261 2e-70 3DFJ-A nrPDB 261 2e-70 1FDP-A nrPDB 261 2e-70 1SC8-U nrPDB 260 5e-70 2F91-A nrPDB 259 8e-70 1YC0-A nrPDB 258 2e-69 4MPW-A nrPDB 258 2e-69 1C5M-D nrPDB 257 3e-69 4Z6A-H nrPDB 257 3e-69 2OCV-B nrPDB 257 3e-69 3TK9-A nrPDB 256 8e-69 6AOD-C nrPDB 255 1e-68 4DGJ-A nrPDB 255 2e-68 1MZD-A nrPDB 255 2e-68 1ETT-H nrPDB 254 2e-68 1FIZ-A nrPDB 254 3e-68 3G01-A nrPDB 254 3e-68 2V35-A nrPDB 254 3e-68 1VR1-H nrPDB 253 5e-68 1BDA-A nrPDB 253 5e-68 1EKB-B nrPDB 253 7e-68 1LTO-A nrPDB 253 7e-68 1ORF-A nrPDB 252 9e-68 1AZZ-A nrPDB 251 3e-67 5FCR-A nrPDB 250 5e-67 1FIW-A nrPDB 250 7e-67 4H4F-A nrPDB 249 7e-67 5LHN-A nrPDB 249 8e-67 1PYT-D nrPDB 249 1e-66 3F6U-H nrPDB 249 1e-66 2R0L-A nrPDB 248 1e-66 5XRF-A nrPDB 247 3e-66 1KYN-A nrPDB 246 6e-66 3P8G-A nrPDB 246 9e-66 1A5I-A nrPDB 245 2e-65 4Q7Y-A nrPDB 243 5e-65 2OQ5-A nrPDB 243 6e-65 5TO3-B nrPDB 243 7e-65 2RDL-A nrPDB 243 7e-65 2XRC-A nrPDB 242 9e-65 4XDE-A nrPDB 240 3e-64 1FUJ-A nrPDB 239 1e-63 4KKD-A nrPDB 238 2e-63 1ELT-A nrPDB 237 3e-63 1FON-A nrPDB 237 4e-63 3RP2-A nrPDB 237 5e-63 1Q3X-A nrPDB 237 5e-63 4IGD-A nrPDB 234 3e-62 1ZJK-A nrPDB 233 5e-62 4BXW-A nrPDB 232 9e-62 4FXG-H nrPDB 232 9e-62 2XXL-A nrPDB 232 1e-61 2ZKS-A nrPDB 232 1e-61 4IW4-E nrPDB 232 1e-61 4DJZ-B nrPDB 230 6e-61 5UBM-A nrPDB 225 1e-59 1ELV-A nrPDB 225 2e-59 5O32-I nrPDB 222 1e-58 5KWM-A nrPDB 220 4e-58 1YM0-A nrPDB 218 2e-57 1GPZ-A nrPDB 217 3e-57 4J1Y-A nrPDB 217 3e-57 2OLG-A nrPDB 217 5e-57 1MD7-A nrPDB 217 5e-57 1AE5-A nrPDB 216 7e-57 2QY0-B nrPDB 216 8e-57 1EQ9-A nrPDB 216 1e-56 2PKA-B nrPDB 215 1e-56 1PPF-E nrPDB 211 3e-55 1PQ7-A nrPDB 209 8e-55 6BQM-A nrPDB 208 1e-54 4X0L-C nrPDB 206 8e-54 2B9L-A nrPDB 205 1e-53 4WJG-C nrPDB 205 1e-53 4LK4-A nrPDB 204 3e-53 3I77-A nrPDB 202 1e-52 2ASU-B nrPDB 199 9e-52 1SI5-H nrPDB 198 2e-51 3BEU-A nrPDB 196 5e-51 4F4O-C nrPDB 196 1e-50 2HLC-A nrPDB 195 1e-50 2FMJ-A nrPDB 193 6e-50 3H7T-A nrPDB 181 3e-46 5XW8-A nrPDB 178 3e-45 1M9U-A nrPDB 169 1e-42 3H7O-A nrPDB 166 1e-41 1AKS-B nrPDB 153 7e-38 3VGC-B nrPDB 151 3e-37 1RIW-B nrPDB 151 3e-37 2JET-B nrPDB 150 6e-37 2I6S-A nrPDB 149 1e-36 1BBR-H nrPDB 146 1e-35 2WIN-I nrPDB 141 3e-34 1DLE-A nrPDB 139 9e-34 2OK5-A nrPDB 138 3e-33 2KAI-A nrPDB 128 4e-30 3RU4-E nrPDB 119 2e-27 1BBR-E nrPDB 119 2e-27 2HNT-F nrPDB 118 4e-27 2JET-C nrPDB 116 9e-27 1EPT-B nrPDB 104 3e-23 Sequences not found previously or not previously below threshold: 3F1S-B nrPDB 89 2e-18 3H5C-B nrPDB 86 2e-17 2HNT-C nrPDB 81 6e-16 2HNT-E nrPDB 74 8e-14 1P3E-A nrPDB 41 4e-04 2EA3-A nrPDB 35 0.028 2PFE-A nrPDB 35 0.038 2SFA-A nrPDB 34 0.069 2OUA-A nrPDB 34 0.094 1HPG-A nrPDB 32 0.26 2SGA-A nrPDB 32 0.26 3LT3-A nrPDB 32 0.34 5ILB-A nrPDB 31 0.68 4FLN-A nrPDB 31 0.68 3W95-A nrPDB 31 0.76 4FVB-A nrPDB 31 0.78 5JYK-A nrPDB 30 0.97 5ILA-A nrPDB 30 1.3 2M5T-A nrPDB 29 1.4 2HRV-A nrPDB 29 1.9 4B6E-A nrPDB 27 7.5 6FE6-A nrPDB 27 9.3 4U01-A nrPDB 27 9.9 4K8B-A nrPDB 27 9.9 >4NFE-A nrPDB Length = 237 Score = 379 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 237 >3QUM-P nrPDB Length = 237 Score = 350 bits (899), Expect = 3e-97, Method: Composition-based stats. Identities = 188/237 (79%), Positives = 210/237 (88%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECEKHSQPWQV V S G A CGGVLVHPQWVLTAAHC++ S + LGRH+LF PE Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHDLMLLRLSEPA++TD VKV+ LPTQ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EPALGTTCYASGWGSIEPEEFL P+ LQCV LH++SND+CA+ + +KVT+FMLCAG WTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P++YTKVVHYRKWIKDTI ANP Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 237 >1SGF-G nrPDB Length = 237 Score = 347 bits (891), Expect = 3e-96, Method: Composition-based stats. Identities = 142/237 (59%), Positives = 174/237 (73%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG++CEK+SQPW VAVY + CGGVL+ P WVLTAAHC N +VWLG++NLF+ E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q VS + PHP +NMSL++ + D S+DLMLLRLS+PA ITD VK + LPT+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP LG+TC ASGWGSI P +F L CV+L LL N+ CA+A+ EKVT+ MLCAG G Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTC GDSGGPL+C+GVLQGITSWG PC P+ P VYTK+ + WIKDT+A NP Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKNP 237 >1SPJ-A nrPDB Length = 238 Score = 344 bits (883), Expect = 2e-95, Method: Composition-based stats. Identities = 155/237 (65%), Positives = 184/237 (77%), Gaps = 1/237 (0%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGGWECE+HSQPWQ A+Y CGG+LVH QWVLTAAHC+ N Q+WLGRHNLF+ E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA-KITDVVKVLGLPT 143 +T Q V VS SFPHP +NMSLL++ + + DED SHDLMLLRL+EPA ITD VKV+ LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 +EP +G+TC ASGWGSIEPE F P LQCV L +L ND C +A+ +KVT+FMLC G Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTC GDSGGPL+C+GVLQG+TSWG PC P KP+V +V+ Y KWI+DTIA N Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >1F7Z-A nrPDB Length = 233 Score = 329 bits (845), Expect = 6e-91, Method: Composition-based stats. Identities = 106/236 (44%), Positives = 141/236 (59%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ C+++S P+QV++ S G+ CGG L++ QWV++AAHC K QV LG HN+ E Sbjct: 11 IVGGYTCQENSVPYQVSLNS-GYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q V + HP ++ L ++D+ML++LS P K+ V + LP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTL-----------NNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GT C SGWG+ P LQC+ LL C +Y K+T+ M+C G G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C GDSGGP+VCNG LQGI SWG CALP+ P VYTKV +Y WI+DTIAAN Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >1SGF-A nrPDB Length = 240 Score = 328 bits (842), Expect = 1e-90, Method: Composition-based stats. Identities = 137/245 (55%), Positives = 174/245 (71%), Gaps = 5/245 (2%) Query: 17 AVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLG 76 A P +QS++ +CE +SQPW VAVY CGGVL+ WVLTAAHC QVWLG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 ++N E E + Q VS + PHP +NMSLL + +P++D S+DLMLLRLS+PA ITDVV Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 K + LPT+EP LG+TC ASGWGS P +F P LQCV+L LL N+ C +A+ KVT+ M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 LCAG GG TC DSGGPL+C+G+LQGITSWGPEPC P +P+VYTK++ + WI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 IAANP 261 +A NP Sbjct: 236 MANNP 240 >4AN7-A nrPDB Length = 231 Score = 327 bits (840), Expect = 2e-90, Method: Composition-based stats. Identities = 104/238 (43%), Positives = 138/238 (57%), Gaps = 13/238 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 +IVGG+ C +S P+QV++ S G CGG L++ QWV++AAHC K QV LG HN+ Sbjct: 7 DKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E Q + + HP +N + L +D+ML++LS PA + V + LP Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSSPATLNSRVATVSLP 114 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 A GT C SGWG+ + P LQC+ +LS+ C +Y ++T M+C G Sbjct: 115 RSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFL 174 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VCNG LQGI SWG CA KP VYTKV +Y WI+ TIAAN Sbjct: 175 EGGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >4WWY-A nrPDB Length = 224 Score = 327 bits (838), Expect = 4e-90, Method: Composition-based stats. Identities = 107/236 (45%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ CE++S P+QV++ S G+ CGG L++ QWV++A HC K QV LG HN+ E Sbjct: 1 IVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + + HP Y+ L ++D+ML++LS A I V + LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 PA GT C SGWG+ P LQC+ +LS C +Y K+T M C G G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C DSGGP+VCNG LQG+ SWG + CA KP VYTKV +Y KWIK+TIAAN Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >5C67-A nrPDB Length = 224 Score = 324 bits (830), Expect = 3e-89, Method: Composition-based stats. Identities = 106/236 (44%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K QV LG HN+ E Sbjct: 1 IVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + + HP YN L +D+ML++LS PA I V + LPT Sbjct: 60 GNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 PA GT C SGWG+ P L+C+ +L+ C +Y K+T M C G G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C D+GGP+VCNG LQG+ SWG CA +P VYTKV +Y WIKDTIAAN Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >5FXL-A nrPDB Length = 246 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 103/238 (43%), Positives = 139/238 (58%), Gaps = 13/238 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 +IVGG+ C ++ P+QV++ S G+ CGG L++ QWV++AAHC K QV LG N+ Sbjct: 22 DKIVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINV 80 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E Q + S S HP YN + L ++D+ML++L A + V + LP Sbjct: 81 VEGNEQFISASKSIVHPSYNSNTL-----------NNDIMLIKLKSAASLNSRVASISLP 129 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 T + GT C SGWG+ + P L+C+ +LS+ C AY ++T M CAG Sbjct: 130 TSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYL 189 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VC+G LQGI SWG CA KP VYTKV +Y WIK TIA+N Sbjct: 190 EGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >1A0J-A nrPDB Length = 223 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 103/236 (43%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+EC K+S +Q ++ S G+ CGG L+ WV++AAHC K QV LG HN+ E Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 T Q + HP YN L +D+ML++LS+PA + V + LP+ Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNL-----------DNDIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 + GT C SGWG++ P +L+C+ L +LS+ C AY ++T M CAG G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKD+C GDSGGP+VCNG LQG+ SWG CA KP VYTKV +YR WI T+++N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1AO5-A nrPDB Length = 237 Score = 319 bits (819), Expect = 7e-88, Method: Composition-based stats. Identities = 136/236 (57%), Positives = 168/236 (71%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG+ CEK+SQPWQVAVY CGGVL+ WVLTAAHC +VWLG++ LF+ E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q VS SFPHP +NMSLL Q++ P D S DLMLLRLS+PA ITDVVK + LPT+ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP G+ C ASGWGSI P + +P LQCV + LL N+ CA+ Y +KVT+ MLCAG G Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKDTC DSGGPL+C+G+LQG TS+GP PC P PA+YT ++ + WIKDT+ N Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >1TON-A nrPDB Length = 235 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 134/237 (56%), Positives = 165/237 (69%), Gaps = 2/237 (0%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG++CEK+SQPWQVAV CGGVL+ P WV+TAAHC N QV LGR+NLF+ E Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 QR V SF HP Y ++ + + +P D S+DLMLL LSEPA IT VKV+ LPT+ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP +G+TC ASGWGS P E + LQCV++HLLSN+ C Y + VT+ MLCAG G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 GKDTC GDSGGPL+C+GVLQGITS G PCA P+ PA+Y K++ + WIK + NP Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP 235 >1UTJ-A nrPDB Length = 242 Score = 316 bits (810), Expect = 7e-87, Method: Composition-based stats. Identities = 98/237 (41%), Positives = 136/237 (57%), Gaps = 14/237 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 +IVGG+EC+ +SQP QV++ S G+ CGG LV+ WV++AAHC K +V LG HN+ Sbjct: 19 DKIVGGYECKPYSQPHQVSLNS-GYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKV 77 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E + Q + S HP Y+ + +D+ML++LS+PA + V+ + LP Sbjct: 78 TEGSEQFISSSRVIRHPNYSSYNI-----------DNDIMLIKLSKPATLNTYVQPVALP 126 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 T GT C SGWG+ LQC+++ +LS C +Y +T M CAG Sbjct: 127 TSCAPAGTMCTVSGWGNTMSSTAD-SNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYL 185 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 GGKD+C GDSGGP+VCNG LQG+ SWG CA P P VY KV + W+ T+A+ Sbjct: 186 EGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFNDWLTSTMAS 241 >1GVZ-A nrPDB Length = 237 Score = 309 bits (791), Expect = 9e-85, Method: Composition-based stats. Identities = 144/236 (61%), Positives = 171/236 (72%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GGWECEKHS+PWQVAVY G CGGVLVHPQWVLTAAHC+ + Q+WLGRHNL + E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 DT Q VS SF P +++SLLK + LRP +D SHDLMLLRL++PA+ITD VK+L LPTQ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 EP LG+TCY SGWG I +LQCV L L SN+ CARAY EK+TEF+LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 C GDSGG L+C+GV QGITSWG CA V+TKV+ ++KWIK+TI N Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1NPM-A nrPDB Length = 225 Score = 305 bits (783), Expect = 9e-84, Method: Composition-based stats. Identities = 112/233 (48%), Positives = 141/233 (60%), Gaps = 9/233 (3%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G EC HSQPWQ A++ CGGVLV +WVLTAAHC K+ V LG H+L + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + V+ S HP YN S ED SHD+ML+RL A + D VK + L Sbjct: 61 QPEQEIQVAQSIQHPCYNNS--------NPEDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 P +G C SGWG++ + P +L C + + S + C RAY K+TE M+CAG + Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SN 171 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G DTC GDSGGPLVC+G+LQGITSWG +PC PEKP VYTK+ Y WIK T+ Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1FXY-A nrPDB Length = 228 Score = 305 bits (781), Expect = 1e-83, Method: Composition-based stats. Identities = 97/239 (40%), Positives = 121/239 (50%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRHNLF 81 IVGG+ C+ PWQ + CGG ++ ++LTAAHCL K +V +G N Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E V H + E D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKHNRF-----------TKETYDFDIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 PT PA GT C SGWG+ P LQC+ +LS C +Y K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VCNG LQG+ SWG + CA KP VYTKV +Y KWIK+TIAAN Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >5MS3-A nrPDB Length = 228 Score = 304 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 105/236 (44%), Positives = 134/236 (56%), Gaps = 9/236 (3%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 ++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 G C SGWG++ P +L C + + C AY ++T+ M+CAG + Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SK 171 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I + Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >2TLD-E nrPDB Length = 220 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 102/236 (43%), Positives = 137/236 (58%), Gaps = 16/236 (6%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+ C ++ P+QV++ S G+ CGG L++ QWV++AAHC K QV LG N+ E Sbjct: 1 IVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q + S S HP YN + L ++D+ML++L A + V + LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTL-----------NNDIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 + GT C SGWG+ + P L+C+ +LS+ C AY ++T M CAGL Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE-- 166 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G D+C GDSGGP+VC+G LQGI SWG CA KP VYTKV +Y WIK TIA+N Sbjct: 167 GGDSCQGDSGGPVVCSGKLQGIVSWGS-GCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >2PSX-A nrPDB Length = 227 Score = 292 bits (749), Expect = 8e-80, Method: Composition-based stats. Identities = 100/238 (42%), Positives = 141/238 (59%), Gaps = 14/238 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF-E 82 I+ G +C+ H+QPWQ A+ +CG VLVHPQW+LTAAHC KK +V LG ++L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E Q S PHP Y+ S+DLML++L+ + T V+ + + Sbjct: 61 YESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 + P+ GT C SGWG+ + + P+ LQC+++ +LS C AY ++ + M CAG Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD- 168 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G+D+C GDSGGP+VCNG LQG+ SWG PCA P +P VYT + + KWI++TI AN Sbjct: 169 KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3BSQ-A nrPDB Length = 227 Score = 292 bits (748), Expect = 9e-80, Method: Composition-based stats. Identities = 99/234 (42%), Positives = 131/234 (55%), Gaps = 13/234 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G C + S PWQVA+ S HCGGVLV+ +WVLTAAHC V LG L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 QR+ S SF HP Y+ +DLML++L+ A+++ +VK + LP++ Sbjct: 61 --AQRIKASKSFRHPGYSTQT-----------HVNDLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GTTC SGWG+ + P L CV + L+S C + Y + + MLCAG+ Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 K+ C GDSGGPLVC G LQG+ SWG PC P P VYT+V + KWI DT+ Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2EEK-A nrPDB Length = 220 Score = 292 bits (747), Expect = 1e-79, Method: Composition-based stats. Identities = 102/234 (43%), Positives = 138/234 (58%), Gaps = 14/234 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 IVGG+EC KHSQ QV++ S G+ CGG LV WV++AAHC K +V LG H++ E Sbjct: 1 IVGGYECTKHSQAHQVSLNS-GYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 T Q + S HP Y+ + ++D+ML++L++PA + V + LPT+ Sbjct: 60 GTEQYISSSSVIRHPNYSSYNI-----------NNDIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 A T C SGWG+ LQC+SL +LS+ CA +Y +T+ M CAG G Sbjct: 109 CAADATMCTVSGWGNT-MSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 GKD+C GDSGGP+VCNGVLQG+ SWG CA + P VY KV W++DT+A Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTMA 220 >6QHB-A nrPDB Length = 223 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 105/235 (44%), Positives = 142/235 (60%), Gaps = 13/235 (5%) Query: 26 VGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPED 85 V G C+K S P+Q A+Y+ G CGGVL+HP WVLTAAHC K N QV+LG+HNL + E Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQES 61 Query: 86 TGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQE 145 + ++ V + HP Y+ + D+MLLRL+ PAK++++++ L L Sbjct: 62 SQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLERDC 110 Query: 146 PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGG 205 A T+C+ GWG +F P ++QC +HL+S + C AY ++T+ MLCAG G Sbjct: 111 SAQTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYG 168 Query: 206 KDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 KD+C GDSGGPLVC L+G+ SWG PC EKP VYT V Y WI+ TI A Sbjct: 169 KDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >5ZFH-A nrPDB Length = 224 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 93/234 (39%), Positives = 131/234 (55%), Gaps = 13/234 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+ G++C++ S PWQVA+ HCGGVLV WVLTAAHC QV LG + + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQS 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 Q++ + SF HP Y+ +D+ML+RL EP K++ V+ + LP Sbjct: 61 --AQKIKATKSFRHPGYSTKT-----------HVNDIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 GT+C SGWG+ + P L C + L+S+ C + Y + + + MLCAG+ Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 +TC GDSGGPLVCN LQG+ SWG PC P P VYT+V Y++W+ +T+ Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >4GSO-A nrPDB Length = 232 Score = 287 bits (735), Expect = 4e-78, Method: Composition-based stats. Identities = 90/236 (38%), Positives = 127/236 (53%), Gaps = 11/236 (4%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 ++GG EC+ + P+ +YSHG+ CG L++ +WV+TAAHC N Q+ LG H+ Sbjct: 1 VLGGDECDINEHPFLAFLYSHGY-FCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q F P NMS E D+ML++L +P + + L LP+ Sbjct: 60 EDEQTRNPKEKFICPNKNMS----------EVLDKDIMLIKLDKPISNSKHIAPLSLPSN 109 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 204 P++G+ C GWGSI P C +++L+ ++C AY+ + LCAG+ G Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEG 169 Query: 205 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GKDTC GDSGGPL+CNG QGI S+G C KP +YT V Y WI+ IA N Sbjct: 170 GKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >1EUF-A nrPDB Length = 227 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 90/239 (37%), Positives = 120/239 (50%), Gaps = 20/239 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW---AHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ + CGG LV +VLTAAHCL + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN DE ++D+MLL+L+ A ITD V + L Sbjct: 61 ERERTQQVIPVRRPIPHPDYN-----------DETLANDIMLLKLTRKADITDKVSPINL 109 Query: 142 PTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 P E G C +GWG + LQ V L + S + C + + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRLGVN-MPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G + K++ GDSGGPLVCNGV QGI S+G P VYT++ + WI T+ Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRNDGTT---PDVYTRISSFLSWIHSTMR 224 >2AIQ-A nrPDB Length = 231 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 92/237 (38%), Positives = 130/237 (54%), Gaps = 14/237 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE-P 83 ++GG EC + + VY++G CGG L++ +WVLTA HC + N +++LG HNL Sbjct: 1 VIGGDECNINEHRFLALVYANGSL-CGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 +D +R P F + R D D+ML+RL+ P + + + L LP+ Sbjct: 60 KDALRRFPKEKYFC-----------LNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPS 108 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 P++G+ C GWG+I P C ++++L +C AY + LCAG+ Sbjct: 109 NPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILE 167 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTC GDSGGPL+CNG QGI S G PCA P KP +YTKV Y WI+ I+ N Sbjct: 168 GGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >4E7N-A nrPDB Length = 238 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 104/242 (42%), Positives = 135/242 (55%), Gaps = 17/242 (7%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW--AHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 I+GG EC + + VA+Y+ CGG L++ +WVLTAAHC +KN ++ LG H+ Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 P-EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 P ED RVP F N +L D+ML+RL P K + + L Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTL-----------WDKDIMLIRLDSPVKNSKHIAPFSL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE---KVTEFMLC 198 P+ P++G+ C GWG I P E P CV+++LL +MC Y E T LC Sbjct: 110 PSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLC 169 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 AG+ GGKDTC GDSGGPL+CNG QGI SWG +PCA P KPA YTKV + WI++ IA Sbjct: 170 AGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIA 229 Query: 259 AN 260 N Sbjct: 230 GN 231 >5TJX-A nrPDB Length = 263 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 89/253 (35%), Positives = 129/253 (50%), Gaps = 28/253 (11%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSH---GWAHCGGVLVHPQWVLTAAHCLKK-----NSQV 73 +RIVGG E PWQV++ CGG L+ QWVLTAAHC ++ Sbjct: 13 STRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 72 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 + G L + + H Y +S + +HD+ L++L P + T Sbjct: 73 YSGILELSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLEYT 121 Query: 134 DVVKVLGLPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE- 190 + K + LP++ + T C+ +GWG + + ++ LQ V++ L++N+ C + Y + Sbjct: 122 EFQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQ-NILQKVNIPLVTNEECQKRYQDY 180 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKV 246 K+T+ M+CAG GGKD C GDSGGPLVC L GITSWG E CA E+P VYTKV Sbjct: 181 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKV 239 Query: 247 VHYRKWIKDTIAA 259 Y WI + + Sbjct: 240 AEYMDWILEKTQS 252 >3T2N-A nrPDB Length = 372 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 90/267 (33%), Positives = 127/267 (47%), Gaps = 23/267 (8%) Query: 8 IALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL 67 +A G L RIVGG + PWQV++ G CGG L+ WVLTAAHC Sbjct: 101 LAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCF 160 Query: 68 KKNSQV----WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123 + ++V + + + G ++ V H Y + E++S+D+ L Sbjct: 161 PERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPN-----SEENSNDIAL 215 Query: 124 LRLSEPAKITDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSN 181 + LS P +T+ ++ + LP AL G C +GWG+ + + LQ + ++SN Sbjct: 216 VHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIISN 274 Query: 182 DMCA--RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG--------VLQGITSWGP 231 D+C Y ++ M CAG GG D C GDSGGP VC L GI SWG Sbjct: 275 DVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT 334 Query: 232 EPCALPEKPAVYTKVVHYRKWIKDTIA 258 CAL +KP VYTKV +R+WI I Sbjct: 335 -GCALAQKPGVYTKVSDFREWIFQAIK 360 >6I44-A nrPDB Length = 627 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 87/253 (34%), Positives = 127/253 (50%), Gaps = 28/253 (11%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSH---GWAHCGGVLVHPQWVLTAAHCLKK-----NSQV 73 +RIVGG + PWQV++ CGG L+ QWVLTAAHC ++ Sbjct: 377 STRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 436 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 + G L + + H Y +S + +HD+ L++L P + T Sbjct: 437 YSGILQLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLQYT 485 Query: 134 DVVKVLGLPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE- 190 + K + LP++ + T C+ +GWG ++ LQ V++ L++N+ C + Y + Sbjct: 486 EFQKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQ-NILQKVNIPLVTNEECQKRYQDY 544 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKV 246 K+T+ M+CAG GGKD C GD+GGPLVC L GITSWG E CA E+P VYTKV Sbjct: 545 KITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKV 603 Query: 247 VHYRKWIKDTIAA 259 Y WI + + Sbjct: 604 AEYMDWILEKTQS 616 >1FI8-A nrPDB Length = 228 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 114/242 (47%), Gaps = 22/242 (9%) Query: 25 IVGGWECEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG E + HS+P+ + G CGG L+ +VLTAAHC QV LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E E Q +PV PHP YN + S+D+MLL+L AK + VK L Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE-FML 197 LP + G CY +GWG + P +LQ V L + + C + + Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 168 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 CAG + + GDSGGPLVC V GI S+G + P +TKV + WIK T+ Sbjct: 169 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 225 Query: 258 AA 259 Sbjct: 226 KK 227 >3LC3-A nrPDB Length = 235 Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 119/242 (49%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRHNLFE 82 +VGG + + PWQV + A CGG +V+ +W++TAAHC++ V G HN+ E Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T Q+ V PH YN ++ K +HD+ LL L EP + V + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINK---------YNHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 197 +E G+ Y SGWG + + LQ + + L+ C R+ + M Sbjct: 112 DKEYTNIFLKFGS-GYVSGWGRV-FHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMF 169 Query: 198 CAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 CAG GG+D+C GDSGGP V L GI SWG E CA+ K +YTKV Y WI Sbjct: 170 CAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >1X7A-C nrPDB Length = 235 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 88/242 (36%), Positives = 117/242 (48%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRHNLFE 82 IVGG + PWQV + A CGG +++ +WV+TAAHC++ V G +N E Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T QR V + PH YN ++ K SHD+ LL L EP + V + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNK---------YSHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 197 +E G+ Y SGWG + LQ + + L+ C R+ + M Sbjct: 112 DKEYTNIFLKFGS-GYVSGWGRV-FNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMF 169 Query: 198 CAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 CAG GGKD+C GDSGGP V L GI SWG E CA+ K +YTKV Y WI Sbjct: 170 CAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >2CGA-A nrPDB Length = 245 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 90/259 (34%), Positives = 128/259 (49%), Gaps = 24/259 (9%) Query: 12 VGCTGAVPLIQ--SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHC-L 67 G P++ SRIV G E S PWQV++ G+ CGG L++ WV+TAAHC + Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV 60 Query: 68 KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V G + + Q++ ++ F + YN + ++D+ LL+LS Sbjct: 61 TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTI-----------NNDITLLKLS 109 Query: 128 EPAKITDVVKVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 A + V + LP+ + A GTTC +GWG P LQ SL LLSN C Sbjct: 110 TAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCK 169 Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPA 241 + + K+ + M+CAG G +C GDSGGPLVC L GI SWG C+ P Sbjct: 170 KYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPG 226 Query: 242 VYTKVVHYRKWIKDTIAAN 260 VY +V W++ T+AAN Sbjct: 227 VYARVTALVNWVQQTLAAN 245 >1OP0-A nrPDB Length = 234 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 91/237 (38%), Positives = 129/237 (54%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 ++GG EC+ + + VA ++ CGG L++P+WV+TAAHC + Q+ LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q F P N +E D+ML++L +P + + L LP+ Sbjct: 61 EDEQTRNPKEKFICPNKN----------NNEVLDKDIMLIKLDKPISNSKHIAPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE-FMLCAGLWT 203 P++G+ C GWGSI P + P C +++LL + +C Y E + E LCAG+ Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTCGGDSGGPL+CNG QGI S+G PC KP +YT V Y WI+ IA N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >2F83-A nrPDB Length = 625 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 89/254 (35%), Positives = 127/254 (50%), Gaps = 28/254 (11%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHG---WAHCGGVLVHPQWVLTAAHCLKKN-----SQ 72 I+ RIVGG + PWQV +++ CGG ++ QW+LTAAHC + Sbjct: 384 IKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILR 443 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 V+ G N E ++ V H Y M+ +S +D+ LL+L Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVNY 492 Query: 133 TDVVKVLGLPTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 TD + + LP++ + T C+ +GWG + + ++ +LQ + L++N+ C + Y Sbjct: 493 TDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRG 551 Query: 191 -KVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTK 245 K+T M+CAG GGKD C GDSGGPL C L GITSWG E CA E+P VYT Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTN 610 Query: 246 VVHYRKWIKDTIAA 259 VV Y WI + A Sbjct: 611 VVEYVDWILEKTQA 624 >1BQY-A nrPDB Length = 234 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 86/237 (36%), Positives = 124/237 (52%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 + GG EC + V +++ CGG L++ WV+TAAHC N Q+ G H+ Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q F P + D++ D+ML++L ++ + L LP+ Sbjct: 61 EDEQTRDPKEKFFCPN----------RKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKVTEFMLCAGLWT 203 P++G+ C GWG P + + P C ++++L + +C AYS +V LCAG+ Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GG+DTC DSGGPL+CNG+ QGI SWG PC P +P VYTKV Y WIK IA N Sbjct: 171 GGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >5UGG-A nrPDB Length = 251 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 95/252 (37%), Positives = 125/252 (49%), Gaps = 34/252 (13%) Query: 23 SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKN-----SQVWLG 76 R+VGG HS PWQV++ + G CGG L+ P+WVLTAAHCL+K+ +V LG Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 79 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 H E Q + VS F P D+ LL+LS PA ITD V Sbjct: 80 AHQEVNLEPHVQEIEVSRLFLEPTR-----------------KDIALLKLSSPAVITDKV 122 Query: 137 KVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKV 192 LP+ + T C+ +GWG + L+ L ++ N +C R + +V Sbjct: 123 IPACLPSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRV 180 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVH 248 LCAG GG D+C GDSGGPLVC +LQG+TSWG CA P KP VY +V Sbjct: 181 QSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSR 239 Query: 249 YRKWIKDTIAAN 260 + WI+ + N Sbjct: 240 FVTWIEGVMRNN 251 >3S69-A nrPDB Length = 234 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 93/237 (39%), Positives = 126/237 (53%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 ++GG EC + VA ++ C G L++ +WVLTAAHC N Q+ LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 + Q F P + DE D+ML++L ++ + L LP+ Sbjct: 61 EDEQTRNPKEKFICPN----------KKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE-FMLCAGLWT 203 P++G+ C+ GWGSI P + P C ++LL + +C Y E +TE LCAG+ Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKDTCGGDSGGPL+CNG QGI S+G PC KP VYTKV Y WI+ IA N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >4DUR-A nrPDB Length = 791 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 95/252 (37%), Positives = 125/252 (49%), Gaps = 34/252 (13%) Query: 23 SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKN-----SQVWLG 76 R+VGG HS PWQV++ + G CGG L+ P+WVLTAAHCL+K+ +V LG Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 619 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 H E Q + VS F P D+ LL+LS PA ITD V Sbjct: 620 AHQEVNLEPHVQEIEVSRLFLEPTR-----------------KDIALLKLSSPAVITDKV 662 Query: 137 KVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKV 192 LP+ + T C+ +GWG + L+ L ++ N +C R + +V Sbjct: 663 IPACLPSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRV 720 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVH 248 LCAG GG D+C GDSGGPLVC +LQG+TSWG CA P KP VY +V Sbjct: 721 QSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSR 779 Query: 249 YRKWIKDTIAAN 260 + WI+ + N Sbjct: 780 FVTWIEGVMRNN 791 >2BDH-A nrPDB Length = 223 Score = 267 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 95/236 (40%), Positives = 132/236 (55%), Gaps = 14/236 (5%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF-EP 83 I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q V S S HP YN LL +DLML++L E +D ++ + + + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLA-----------NDLMLIKLDESVSESDTIRSISIAS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >3K65-B nrPDB Length = 308 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 80/272 (29%), Positives = 120/272 (44%), Gaps = 43/272 (15%) Query: 18 VPLIQSRIVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-------- 67 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL Sbjct: 43 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 102 Query: 68 --KKNSQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 + + V +G+H+ E +++ + + HP YN E+ D+ L+ Sbjct: 103 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 152 Query: 125 RLSEPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCV 174 +L +P +D + + LP +E A G +GWG+++ +P LQ V Sbjct: 153 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 212 Query: 175 SLHLLSNDMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC------NGVLQG 225 +L ++ +C + ++T+ M CAG GK D C GD+GGP V G Sbjct: 213 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMG 272 Query: 226 ITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 I SWG E C K YT V +KWI+ I Sbjct: 273 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >5GVT-A nrPDB Length = 250 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 84/247 (34%), Positives = 119/247 (48%), Gaps = 22/247 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSH---GWAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRHN 79 IVGG PWQV++ CGG ++ QWVLTAAHC VW Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 + + + P S L+ HQ + E ++D+ L++L P T+ K + Sbjct: 61 ILSLSEITKETPSSRI-------KELIIHQEYKVSEG-NYDIALIKLQTPLNYTEFQKPI 112 Query: 140 GLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF-M 196 LP++ + T C+ +GWG + + + LQ ++ L+ N+ C + Y + V M Sbjct: 113 SLPSKADTNTIYTNCWVTGWGYTKEQGETQ-NILQKATIPLVPNEECQKKYRDYVINKQM 171 Query: 197 LCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 +CAG GG D C GDSGGPLVC L GITSWG E CA ++P VYTKV Y W Sbjct: 172 ICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWG-EGCARKDQPGVYTKVSEYMDW 230 Query: 253 IKDTIAA 259 I + + Sbjct: 231 ILEKTQS 237 >3S9B-A nrPDB Length = 234 Score = 266 bits (680), Expect = 7e-72, Method: Composition-based stats. Identities = 88/240 (36%), Positives = 125/240 (52%), Gaps = 17/240 (7%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF- 81 +VGG EC + P+ VA+Y+ + HC G L++ +WVLTAAHC ++N ++ LG H+ Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 ED RVP F + + D+ML+RL P + + + L Sbjct: 61 RNEDEQIRVPRGKYFC-----------LNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF-MLCAG 200 P++ +G+ C GWG I P C ++ ++ + C Y + LCAG Sbjct: 110 PSRSRGVGSRCRIMGWGKISTT--TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAG 167 Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 + GG+DTC GDSGGPL+CNG + GI + G EPC KPAVYTKV Y WI+ IA N Sbjct: 168 ILKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >5LPF-A nrPDB Length = 234 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 93/233 (39%), Positives = 120/233 (51%), Gaps = 5/233 (2%) Query: 28 GWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTG 87 G C + SQPWQV++++ HC GVLV WVLTAAHC K +G +L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 65 Query: 88 QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA 147 Q + S HP Y+ R DE HDLMLL+L+ P + V+ L LP + Sbjct: 66 QLRRTTRSVVHPKYHQGSGPILPRRTDE---HDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKD 207 G C +GWG+ + L C S+ +LS C Y VT M+CAG G+D Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQD 181 Query: 208 TCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 C DSGGPLVC+ LQGI SWG PC + PAVYT++ Y WI I +N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >3NXP-A nrPDB Length = 424 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 81/272 (29%), Positives = 120/272 (44%), Gaps = 43/272 (15%) Query: 18 VPLIQSRIVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-------- 67 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL Sbjct: 159 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 218 Query: 68 --KKNSQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 + + V +G+H+ E +++ + + HP YN E+ D+ L+ Sbjct: 219 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 268 Query: 125 RLSEPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCV 174 +L +P +D + + LP +E A G +GWG+++ +P LQ V Sbjct: 269 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 328 Query: 175 SLHLLSNDMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC------NGVLQG 225 +L ++ +C + ++T+ M CAG GK D C GDSGGP V G Sbjct: 329 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 388 Query: 226 ITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 I SWG E C K YT V +KWI+ I Sbjct: 389 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 419 >1MKW-K nrPDB Length = 308 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 83/272 (30%), Positives = 120/272 (44%), Gaps = 43/272 (15%) Query: 18 VPLIQSRIVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-----KKN 70 I+ RIV G + E PWQV ++ CG L+ +WVLTAAHCL KN Sbjct: 43 ESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 102 Query: 71 SQV-----WLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 V +G+H+ E +++ + + HP YN E+ D+ LL Sbjct: 103 FTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNW----------KENLDRDIALL 152 Query: 125 RLSEPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGS-----IEPEEFLRPRSLQCV 174 +L P +++D + + LP ++ A G +GWG+ ++P LQ V Sbjct: 153 KLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVV 212 Query: 175 SLHLLSNDMCARAYSEKVTEFMLCAGLWTG---GKDTCGGDSGGPLVC------NGVLQG 225 +L L+ +C + ++T+ M CAG G D C GDSGGP V G Sbjct: 213 NLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMG 272 Query: 226 ITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 I SWG E C K YT V +KWI+ I Sbjct: 273 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >1BRU-P nrPDB Length = 241 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 86/252 (34%), Positives = 122/252 (48%), Gaps = 27/252 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHG----WAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRH 78 +VGG + +S PWQV++ CGG LV WVLTAAHC+ + +V LGRH Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 +L E V VS H +N + L + +D+ LL+L+ P +TD +++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSN---------GNDIALLKLASPVSLTDKIQL 111 Query: 139 LGLPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYSEKVTE 194 LP L CY +GWG ++ P LQ L ++ C++ + V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRLQTNGA-SPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPE-PCALPEKPAVYTKVVH 248 M+CAG G +C GDSGGPL C G + GI S+G C KP+V+T+V + Sbjct: 171 NMICAG-GDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 YRKWIKDTIAAN 260 Y WI IA N Sbjct: 230 YIDWINSVIANN 241 >4NZQ-A nrPDB Length = 557 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 81/272 (29%), Positives = 120/272 (44%), Gaps = 43/272 (15%) Query: 18 VPLIQSRIVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-------- 67 I RIV G + E PWQV ++ CG L+ +WVLTAAHCL Sbjct: 292 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 351 Query: 68 --KKNSQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 + + V +G+H+ E +++ + + HP YN E+ D+ L+ Sbjct: 352 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 401 Query: 125 RLSEPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCV 174 +L +P +D + + LP +E A G +GWG+++ +P LQ V Sbjct: 402 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 461 Query: 175 SLHLLSNDMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC------NGVLQG 225 +L ++ +C + ++T+ M CAG GK D C GDSGGP V G Sbjct: 462 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 521 Query: 226 ITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 I SWG E C K YT V +KWI+ I Sbjct: 522 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 552 >1KIG-H nrPDB Length = 241 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 78/247 (31%), Positives = 108/247 (43%), Gaps = 25/247 (10%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRHNLF 81 IVGG +C + PWQ + CGG +++ +VLTAAHCL K V +G N Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E V + H + E D+ +LRL P + V L Sbjct: 61 QEEGNEMAHEVEMTVKHSRF-----------VKETYDFDIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 P ++ A T T SG+G + L +L+ + + + C + S +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGRTHEKGRLSS-TLKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG T +D C GDSGGP V + GI SWG E CA K VYTKV ++ KW Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTIAA 259 I + A Sbjct: 228 IDKIMKA 234 >1IAU-A nrPDB Length = 227 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 87/240 (36%), Positives = 115/240 (47%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN + S+D+MLL+L AK T V+ L L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF-MLC 198 P+ + + G TC +GWG P +LQ V + + + C LC Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 168 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G K + GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 169 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN-GMP--PRACTKVSSFVHWIKKTMK 225 >1P57-B nrPDB Length = 255 Score = 262 bits (671), Expect = 9e-71, Method: Composition-based stats. Identities = 86/250 (34%), Positives = 122/250 (48%), Gaps = 23/250 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQV----WLGRHNL 80 IVGG + PWQV++ G CGG L+ WVLTAAHC + ++V + + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 + G ++ V H Y + E++S+D+ L+ LS P +T+ ++ + Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPN-----SEENSNDIALVHLSSPLPLTEYIQPVC 115 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVTEFM 196 LP AL G C +GWG+ + + LQ + ++SND+C Y ++ M Sbjct: 116 LPAAGQALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIISNDVCNGADFYGNQIKPKM 174 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNG--------VLQGITSWGPEPCALPEKPAVYTKVVH 248 CAG GG D C GDSGGP VC L GI SWG CAL +KP VYTKV Sbjct: 175 FCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSD 233 Query: 249 YRKWIKDTIA 258 +R+WI I Sbjct: 234 FREWIFQAIK 243 >3E0N-B nrPDB Length = 271 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 116/255 (45%), Gaps = 32/255 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I GG PWQV++ G CGG LV QWVL+AAHC K+ +V LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + + + PHP Y E S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 GLPTQEPAL--GTTCYASGWGSIEPE-EFLRPRSLQCVSLHLLSNDMCARAY-------- 188 LP + + G C +GWG + P L P+ LQ + + L+S + C Y Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 189 SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYT 244 V E M+CAG GGKD C GDSGGPL C L GI SWG + C +P VYT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIAA 259 Y WI+ + Sbjct: 229 LASSYASWIQSKVTE 243 >3W94-A nrPDB Length = 235 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 78/246 (31%), Positives = 111/246 (45%), Gaps = 27/246 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQ------VWLGRH 78 +VGG EK + PW V+++ G CG L+ W+LTAAHC+ + LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 79 NLFE-PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 Q V + YN + D+ ++ L +P T+ V Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEA-----------DIAMMHLQQPVNFTEWVL 109 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVTE 194 + L +++ G C+ +GWG + E P LQ + L+ D C R E T Sbjct: 110 PVCLASEDQHFPAGRRCFIAGWGR-DAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTS 168 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 MLCAG GG D+C GDSGGPL+C L G+TS+G C PE+P Y +V + Sbjct: 169 SMLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFT 227 Query: 251 KWIKDT 256 WI +T Sbjct: 228 SWIAET 233 >1NN6-A nrPDB Length = 228 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 91/242 (37%), Positives = 123/242 (50%), Gaps = 22/242 (9%) Query: 25 IVGGWECEKHSQPWQVAV----YSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG EC+ HS+P+ + + CGG L+ +VLTAAHC ++ V LG HN+ Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 62 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E EDT Q++ V F HP YN S L H D+MLL+L E A +T V L Sbjct: 63 TEEEDTWQKLEVIKQFRHPKYNTSTLHH-----------DIMLLKLKEKASLTLAVGTLP 111 Query: 141 LPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 P+Q G C +GWG + +LQ V L L+ C+ + + LC Sbjct: 112 FPSQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACS-HFRDFDHNLQLC 169 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G K GDSGGPL+C GV QGI S+G + + PAV+T++ HYR WI + Sbjct: 170 VGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQ 226 Query: 259 AN 260 AN Sbjct: 227 AN 228 >3DFJ-A nrPDB Length = 263 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 115/255 (45%), Gaps = 32/255 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I GG PWQV++ G CGG LV QWVL+AAHC K+ +V LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + + + PHP Y E S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 GLPTQEPAL--GTTCYASGWGSIEPE-EFLRPRSLQCVSLHLLSNDMCARAY-------- 188 LP + G C +GWG + P L P+ LQ + + L+S + C Y Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 189 SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYT 244 V E M+CAG GGKD C GDSGGPL C L GI SWG + C +P VYT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIAA 259 Y WI+ + Sbjct: 229 LASSYASWIQSKVTE 243 >1FDP-A nrPDB Length = 235 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 96/249 (38%), Positives = 133/249 (53%), Gaps = 26/249 (10%) Query: 20 LIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL----KKNSQVWL 75 + RI+GG E E H++P+ +V +G CGGVLV QWVL+AAHCL QV L Sbjct: 3 PPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLL 62 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 G H+L +PE + + V + PHP + HDL+LL+LSE A + Sbjct: 63 GAHSLSQPEPSKRLYDVLRAVPHPD-----------SQPDTIDHDLLLLQLSEKATLGPA 111 Query: 136 VKVLGLP----TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYS 189 V+ LP ++ A GT C +GWG + RP SLQ V L +L C R + Sbjct: 112 VRP--LPWQRVDRDVAPGTLCDVAGWGIVN-HAGRRPDSLQHVLLPVLDRATCNRRTHHD 168 Query: 190 EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHY 249 +TE ++CA + +D+C GDSGGPLVC GVL+G+ + G C +KP +YT+V Y Sbjct: 169 GAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASY 226 Query: 250 RKWIKDTIA 258 WI +A Sbjct: 227 AAWIDSVLA 235 >1SC8-U nrPDB Length = 262 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 85/270 (31%), Positives = 127/270 (47%), Gaps = 34/270 (12%) Query: 8 IALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWA-----HCGGVLVHPQWVLT 62 + G P + +I+GG +QPW A+Y CGG L+ P WV++ Sbjct: 1 LKFQCGQKTLRP--RFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVIS 58 Query: 63 AAHCL-----KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDS 117 A HC K++ V+LGR L + V + H Y+ L H Sbjct: 59 ATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHH-------- 110 Query: 118 SHDLMLLRLSEP----AKITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSL 171 +D+ LL++ A+ + ++ + LP+ +P GT+C +G+G ++L P L Sbjct: 111 -NDIALLKIRSKEGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQL 169 Query: 172 QCVSLHLLSNDMCAR--AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQG 225 + + L+S+ C + Y +VT MLCA D+C GDSGGPLVC L G Sbjct: 170 KMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTG 229 Query: 226 ITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 I SWG CAL +KP VYT+V H+ WI+ Sbjct: 230 IVSWG-RGCALKDKPGVYTRVSHFLPWIRS 258 >2F91-A nrPDB Length = 237 Score = 259 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 116/246 (47%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVAVYS----HGWAHCGGVLVHPQWVLTAAHCLKKN-------SQV 73 IVGG + P+Q++ + CG + + + +TA HC+ + Q+ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 G ++ E + Q + VS H ++ +LL +D+ LL+LS Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLL-----------DNDISLLKLSGSLTFN 109 Query: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKV 192 D V + LP Q +GWG+ P LQ V++ L+S++ C Y +++ Sbjct: 110 DNVAPIALPEQGHTATGDVIVTGWGTTSE-GGNTPDVLQKVTVPLVSDEDCRADYGADEI 168 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCNGV----LQGITSWGPEPCALPEKPAVYTKVVH 248 + M+CAG+ GGKD+C GDSGGPL + L GI SWG CA P P VYT+V + Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSY 227 Query: 249 YRKWIK 254 + WIK Sbjct: 228 HVDWIK 233 >1YC0-A nrPDB Length = 283 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 84/259 (32%), Positives = 119/259 (45%), Gaps = 29/259 (11%) Query: 17 AVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNS 71 ++ RI+GG S PW A+Y G + C G LVH WV++AAHC + + Sbjct: 28 KRTFLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSV 86 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP-- 129 V LG+H D Q + P+ LY++ S HDL+L+RL + Sbjct: 87 SVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVF----------NPSDHDLVLIRLKKKGD 136 Query: 130 --AKITDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 A + V+ + LP G C +GWG ++ SL+ + L+++ C+ Sbjct: 137 RCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCS 196 Query: 186 --RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEK 239 Y ++ MLCAG + D C GDSGGPL C L GI SWG + C K Sbjct: 197 SPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHK 255 Query: 240 PAVYTKVVHYRKWIKDTIA 258 P VYT+V +Y WI D I Sbjct: 256 PGVYTRVANYVDWINDRIR 274 >4MPW-A nrPDB Length = 245 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 91/262 (34%), Positives = 129/262 (49%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW---AHCGGVLVHPQWVLTAAHCLKKNSQ------VWL 75 IVGG E + PWQV++ HG CGG L+HPQWVLTAAHC+ + + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 +L+ + Q +PVS HP + + + D+ LL L EP K++ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVKVSSH 106 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRS-LQCVSLHLLSNDMCARAYS--- 189 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 107 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEK 239 V + MLCAG +D+C GDSGGPLVC + G+ SWG E CA P + Sbjct: 167 YTGDDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 223 Query: 240 PAVYTKVVHYRKWIKDTIAANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >1C5M-D nrPDB Length = 255 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 106/246 (43%), Gaps = 25/246 (10%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRHNLF 81 IVGG EC+ PWQ + CGG ++ ++LTAAHCL K +V +G N Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E V H + E D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKHNRF-----------TKETYDFDIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 P ++ A T T SG+G + + L+ + + + + C + S +T+ M Sbjct: 110 PERDWAESTLMTQKTGIVSGFGRTHEKG-RQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 168 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252 CAG T +D C GDSGGP V + GI SWG E CA K +YTKV + KW Sbjct: 169 FCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKW 227 Query: 253 IKDTIA 258 I ++ Sbjct: 228 IDRSMK 233 >4Z6A-H nrPDB Length = 249 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 85/251 (33%), Positives = 119/251 (47%), Gaps = 27/251 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 IVGG C K PWQV + +G CGG L++ WV++AAHC K N LG H+ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L E + Q V+ Y ++HD+ LLRL +P +TD V L Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGT-----------TNHDIALLRLHQPVVLTDHVVPL 109 Query: 140 GLPTQEPALGTTCY-----ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE 194 LP + + T + SGWG + + L +++ L C +Y K+TE Sbjct: 110 CLPERTFSERTLAFVRFSLVSGWGQL-LDRGATALELMVLNVPRLMTQDCEASYPGKITE 168 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 +M CAG G KD+C GDSGGP + L GI SWG + CA VYT+V Y Sbjct: 169 YMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYI 227 Query: 251 KWIKDTIAANP 261 +W++ + + P Sbjct: 228 EWLQKLMRSEP 238 >2OCV-B nrPDB Length = 259 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 77/265 (29%), Positives = 117/265 (44%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV GW+ EK PWQV ++ CG L+ +WVLTAAHC+ + + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ LL+L +P Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCVSLHLLSN 181 +D + + LP ++ G +GWG++ ++P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVER 170 Query: 182 DMCARAYSEKVTEFMLCAGL---WTGGKDTCGGDSGGPLVC------NGVLQGITSWGPE 232 +C + ++T+ M CAG T D C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-E 229 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V + WI+ I Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >3TK9-A nrPDB Length = 226 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 86/240 (35%), Positives = 116/240 (48%), Gaps = 22/240 (9%) Query: 25 IVGGWECEKHSQPWQVA---VYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E + HS+P+ + CGG+LV +VLTAAHC + V LG HN+ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E E T Q +PV PHP YN + S+++MLL+L AK T V+ L L Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPK-----------NFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PTQEPA--LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR-AYSEKVTEFMLC 198 P+ + G C +GWG + +LQ V L + + C R + +C Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTVQKDCQCERLFHGNYSRATEIC 167 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G + GDSGGPLVC V QGI S+G + P P VY KV H+ WIK T+ Sbjct: 168 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK-GTP--PGVYIKVSHFLPWIKRTMK 224 >6AOD-C nrPDB Length = 245 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 85/250 (34%), Positives = 124/250 (49%), Gaps = 28/250 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHG---WAHCGGVLVHPQWVLTAAHCLKKN-----SQVWLG 76 IVGG + PWQV +++ CGG ++ QW+LTAAHC +V+ G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 77 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 E ++ V H Y M+ +S +D+ LL+L + TD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVQYTDSQ 109 Query: 137 KVLGLPTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVT 193 + + LP++ + T C+ +GWG + + ++ +LQ + L++N+ C + Y K+T Sbjct: 110 RPISLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRGHKIT 168 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVHY 249 M+CAG GGKD C GD+GGPL C L GITSWG E CA E+P VYT VV Y Sbjct: 169 HKMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEY 227 Query: 250 RKWIKDTIAA 259 WI + A Sbjct: 228 VDWILEKTQA 237 >4DGJ-A nrPDB Length = 235 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 76/245 (31%), Positives = 114/245 (46%), Gaps = 27/245 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGRH 78 IVGG + ++ + PW V +Y CG LV W+++AAHC+ + LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 NLFEPEDTGQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 + +P YN +D+ ++ L TD ++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRR-----------RKDNDIAMMHLEFKVNYTDYIQ 109 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTE 194 + LP + G C +GWG++ + LQ + LLSN+ C + E +TE Sbjct: 110 PISLPEENQVFPPGRNCSIAGWGTV-VYQGTTADILQEADVPLLSNERCQQQMPEYNITE 168 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 M+CAG GG D+C GDSGGPL+C L G+TS+G E CALP +P VY +V + Sbjct: 169 NMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSRFT 227 Query: 251 KWIKD 255 +WI+ Sbjct: 228 EWIQS 232 >1MZD-A nrPDB Length = 240 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 86/244 (35%), Positives = 133/244 (54%), Gaps = 23/244 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 I+GG E HS+P+ ++ G CGGVL+ PQWVLTAAHC + + V LG H+ Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L + E + Q + + P S + S+D+ML++L AK+ VK+L Sbjct: 63 LSKNEASKQTLEIKKFIP-----------FSRVTSDPQSNDIMLVKLQTAAKLNKHVKML 111 Query: 140 GLPTQEP-ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC-ARAYSEK---VTE 194 + ++ GT C +GWG+ +P+ +L+ V++ +LS +C +++Y +T+ Sbjct: 112 HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 171 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVV-HYRKWI 253 M+CAG G KD+C GD+GGPL+C GV I S G E C + KP +YT + Y+ WI Sbjct: 172 DMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWI 230 Query: 254 KDTI 257 K + Sbjct: 231 KSNL 234 >1ETT-H nrPDB Length = 259 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 81/265 (30%), Positives = 117/265 (44%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-----KKNSQV---- 73 IV G + E PWQV ++ CG L+ +WVLTAAHCL KN V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 74 -WLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 +G+H+ E +++ + + HP YN E+ D+ LL+L P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNW----------KENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGS-----IEPEEFLRPRSLQCVSLHLLSN 181 ++D + + LP ++ A G +GWG+ ++P LQ V+L L+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 170 Query: 182 DMCARAYSEKVTEFMLCAGLWTG---GKDTCGGDSGGPLVC------NGVLQGITSWGPE 232 +C + ++T+ M CAG G D C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG-E 229 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V +KWI+ I Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >1FIZ-A nrPDB Length = 263 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 115/253 (45%), Gaps = 19/253 (7%) Query: 25 IVGGWECEKHSQPWQVAVY------SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRH 78 +VGG E + PW V++ + + CGG+L++ WVLTAAHC K +V R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 E + ++ H+ + +D+ L++++ P + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEI-NDIALIKITPPVPCGPFIGP 119 Query: 139 LGLPTQ---EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVT 193 LP P TC+ +GWG ++ + +LQ + L+ ++C R Y+ ++ Sbjct: 120 GCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIR 179 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAVYTKVV 247 +CAG G DTC GDSGGPL+C V+ GITSWG CA ++P VYT Sbjct: 180 STNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTW 238 Query: 248 HYRKWIKDTIAAN 260 Y WI I +N Sbjct: 239 PYLNWIASKIGSN 251 >3G01-A nrPDB Length = 227 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 84/241 (34%), Positives = 122/241 (50%), Gaps = 22/241 (9%) Query: 25 IVGGWECEKHSQPWQV---AVYSHGW-AHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG E HS+P+ + G CGG LV ++VLTAAHC ++ V LG HN+ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E+T Q +PV+ + PHP YN +D S+D+MLL+L AK T V+ L Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNP-----------DDRSNDIMLLKLVRNAKRTRAVRPLN 109 Query: 141 LPTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTE-FML 197 LP + G CY +GWG + P+ P++L V L + + +C + + Sbjct: 110 LPRRNAHVKPGDECYVAGWGKVTPDG-EFPKTLHEVKLTVQKDQVCESQFQSSYNRANEI 168 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 C G + GDSGGPLVC GI S+G + P+ V+T+V+ + WIK T+ Sbjct: 169 CVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQTDGSAPQ---VFTRVLSFVSWIKKTM 225 Query: 258 A 258 Sbjct: 226 K 226 >2V35-A nrPDB Length = 240 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 123/251 (49%), Gaps = 26/251 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW----AHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRH 78 +VGG E +++S P Q+++ CGG L+ WV+TAAHC+ + +V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 NL + + T Q V V HP +N D + +D+ LLRL++ + V++ Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTD---------DVAAGYDIALLRLAQSVTLNSYVQL 111 Query: 139 LGLPTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP A + CY +GWG L ++LQ L + +C+ + + V Sbjct: 112 GVLPRAGTILANNSPCYITGWGLTRTNGQL-AQTLQQAYLPTVDYAICSSSSYWGSTVKN 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPE-PCALPEKPAVYTKVVHY 249 M+CAG G + C GDSGGPL C + G+TS+ C + KP V+T+V Y Sbjct: 171 SMVCAG-GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAY 229 Query: 250 RKWIKDTIAAN 260 WI + IA+N Sbjct: 230 ISWINNVIASN 240 >1VR1-H nrPDB Length = 261 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 78/269 (28%), Positives = 118/269 (43%), Gaps = 47/269 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW------AHCGGVLVHPQWVLTAAHCL----------K 68 IV G + E PWQV +++ CG L+ +WVLTAAHCL + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 KNSQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 + V +G+H+ E +++ + + HP YN E+ D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 EPAKITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCVSLH 177 +P +D + + LP +E A G +GWG+++ +P LQ V+L Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 170 Query: 178 LLSNDMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC------NGVLQGITS 228 ++ +C + ++T+ M CA GK D C GDSGGP V GI S Sbjct: 171 IVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 WG E C K YT V +KWI+ I Sbjct: 231 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 258 >1BDA-A nrPDB Length = 265 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 85/277 (30%), Positives = 120/277 (43%), Gaps = 42/277 (15%) Query: 11 SVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGW------AHCGGVLVHPQWVLTAA 64 + G Q RI GG + S PWQ A+++ CGG+L+ W+L+AA Sbjct: 1 TCGLR-QYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAA 59 Query: 65 HCLKKNS-----QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH 119 HC ++ V LGR P + Q+ V H ++ D+ + Sbjct: 60 HCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD-----------DDTYDN 108 Query: 120 DLMLLRLS----EPAKITDVVKVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQC 173 D+ LL+L A+ + VV+ + LP + L T C SG+G E L+ Sbjct: 109 DIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKE 168 Query: 174 VSLHLLSNDMCARAY--SEKVTEFMLCAGLWTGGK------DTCGGDSGGPLVC----NG 221 + L + C + + VT+ MLCAG G D C GDSGGPLVC Sbjct: 169 AHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRM 228 Query: 222 VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 L GI SWG C + P VYTKV +Y WI+D + Sbjct: 229 TLVGIISWGL-GCGQKDVPGVYTKVTNYLDWIRDNMR 264 >1EKB-B nrPDB Length = 235 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 79/247 (31%), Positives = 122/247 (49%), Gaps = 31/247 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS------QVWLGRH 78 IVGG + + + PW VA+Y CG LV W+++AAHC+ + + LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 ---NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 NL P+ + + +P YN ++D+ ++ L TD Sbjct: 61 MASNLTSPQ--IETRLIDQIVINPHYN-----------KRRKNNDIAMMHLEMKVNYTDY 107 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-V 192 ++ + LP + G C +GWG++ + LQ + LLSN+ C + E + Sbjct: 108 IQPICLPEENQVFPPGRICSIAGWGAL-IYQGSTADVLQEADVPLLSNEKCQQQMPEYNI 166 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVH 248 TE M+CAG GG D+C GDSGGPL+C +L G+TS+G + CALP +P VY +V Sbjct: 167 TENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPR 225 Query: 249 YRKWIKD 255 + +WI+ Sbjct: 226 FTEWIQS 232 >1LTO-A nrPDB Length = 245 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 88/262 (33%), Positives = 125/262 (47%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW---AHCGGVLVHPQWVLTAAHCLKKNSQ------VWL 75 IVGG E + PWQV++ CGG L+HPQWVLTAAHCL + + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 +L+ + Q +PVS HP + + + D+ LL L EP I+ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYII-----------QTGADIALLELEEPVNISSR 106 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRS-LQCVSLHLLSNDMCARAYS--- 189 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C Y Sbjct: 107 VHTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEK 239 + + MLCAG +D+C GDSGGPLVC + G+ SW E CA P + Sbjct: 167 YTGDDVRIIRDDMLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNR 223 Query: 240 PAVYTKVVHYRKWIKDTIAANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >1ORF-A nrPDB Length = 234 Score = 252 bits (645), Expect = 9e-68, Method: Composition-based stats. Identities = 88/244 (36%), Positives = 124/244 (50%), Gaps = 21/244 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFEP 83 I+GG E HS+P+ V + C G L+ WVLTAAHC L K SQV LG H++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E T Q + V FP+P Y+ + + DL LL+L+E AKI V +L LP Sbjct: 61 EPTKQIMLVKKEFPYPCYDPATREG-----------DLKLLQLTEKAKINKYVTILHLPK 109 Query: 144 Q--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR----AYSEKVTEFML 197 + + GT C +GWG +L+ V + ++ +C ++ + M+ Sbjct: 110 KGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEP-CALPEKPAVYTKVV-HYRKWIKD 255 CAG GG+D+C GDSG PL+C GV +G+TS+G E C P P VY + + WI Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 228 Query: 256 TIAA 259 TI Sbjct: 229 TIKG 232 >1AZZ-A nrPDB Length = 226 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN--SQVWLGRHNLFE 82 IVGG E +S P Q A++ CGG L+ P+W+LTAAHC+ V LG HN+ E Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E T + + H YN ++ S+D+ ++RL P +T + +GLP Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVI-----------SNDIAVIRLPVPVTLTAAIATVGLP 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 + + +GT +GWG L+ V + ++SN C Y VT+ +C Sbjct: 110 STDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG-IVTDGNICI-DS 167 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 261 TGGK TC GDSGGPL NG+ GITS+G P +T+V ++ WI+ P Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQTQTGITP 226 >5FCR-A nrPDB Length = 234 Score = 250 bits (638), Expect = 5e-67, Method: Composition-based stats. Identities = 83/245 (33%), Positives = 121/245 (49%), Gaps = 23/245 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 I+GG E H++P+ +V +G CGG L+ QWVL+AAHC+ + QV LG H+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L PE + V PHP + DL+L +LS+ A + V+ L Sbjct: 61 LSAPEPYKRWYDVQSVVPHPG-----------SRPDSLEDDLILFKLSQNASLGPHVRPL 109 Query: 140 GLP--TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVTEF 195 L +E GT C +GWG + RP L + + +++ C + VT Sbjct: 110 PLQYEDKEVEPGTLCDVAGWGVV-THAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTIN 168 Query: 196 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 M+CA + +DTC GDSG PLVC ++G+ +WG C +KP VYT+V YR WI++ Sbjct: 169 MMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 Query: 256 TIAAN 260 N Sbjct: 227 ITNGN 231 >1FIW-A nrPDB Length = 290 Score = 250 bits (638), Expect = 7e-67, Method: Composition-based stats. Identities = 72/253 (28%), Positives = 113/253 (44%), Gaps = 19/253 (7%) Query: 25 IVGGWECEKHSQPWQVAVY------SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRH 78 I+GG + + PW V++ + + CGG L++ QW+LTAAHC + +V R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 E Y ++ H+ ++ +D+ L++++ P + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEA-NDIALMKITPPVTCGHFIGP 119 Query: 139 LGLPTQ---EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVT 193 LP P + TC+ +GWG ++ LQ + L+ +C R Y+ ++ Sbjct: 120 GCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIR 179 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAVYTKVV 247 +CAG G DTC GDSGGPL+C V+ GITSWG CA ++P VYT Sbjct: 180 STNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTW 238 Query: 248 HYRKWIKDTIAAN 260 Y WI I + Sbjct: 239 SYLNWIASKIGST 251 >4H4F-A nrPDB Length = 249 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 122/251 (48%), Gaps = 30/251 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHG----WAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRH 78 +VGG + HS PWQ+++ CGG L+ +VLTAAHC+ +V +G++ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 NLFEPEDTGQ-RVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 NL ++ G V V H +N LL+ +D+ L++L+E +++D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 109 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYSEKVT 193 V LP ++ L CY +GWG + + LQ ++ + C+R + +V Sbjct: 110 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDWWGFRVK 168 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCN-----GVLQGITSWGP-EPCALPEKPAVYTKVV 247 + M+CAG G C GDSGGPL C + GI S+G C +KP VYT+V Sbjct: 169 KTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 248 HYRKWIKDTIA 258 Y WI + + Sbjct: 228 AYIDWINEKMQ 238 >5LHN-A nrPDB Length = 247 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 80/257 (31%), Positives = 120/257 (46%), Gaps = 33/257 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA------HCGGVLVHPQWVLTAAHCL-----KKNSQV 73 IVGG E +QPW A+Y CGG L+ P WV +AAHC K+N V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP---- 129 +LG+ + V H Y L + +D+ LL++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYH---------NDIALLKIRTSTGQC 111 Query: 130 AKITDVVKVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR- 186 A+ + ++ + LP + + G+ C +G+G ++L P++L+ + L+S++ C + Sbjct: 112 AQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQP 171 Query: 187 -AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPA 241 Y ++ MLCA D+C GDSGGPL+CN L GI SWG CA KP Sbjct: 172 HYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKNKPG 230 Query: 242 VYTKVVHYRKWIKDTIA 258 VYT+V H+ WI+ I Sbjct: 231 VYTRVSHFLDWIQSHIG 247 >1PYT-D nrPDB Length = 251 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 125/263 (47%), Gaps = 29/263 (11%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHG----WAHCGGVLVHPQWVLTAAHCL 67 G P + +R+VGG + HS PWQ+++ CGG L+ P VLTAAHC+ Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 68 KK--NSQVWLGRHNLFEPEDTGQ-RVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 +V LG++NL ++ G V V F H +N L++ +D+ L+ Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVR-----------NDIALI 109 Query: 125 RLSEPAKITDVVKVLGLPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSND 182 +L+E ++ D ++V LP++ L C+ +GWG + + LQ ++ Sbjct: 110 KLAETVELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAE-LQQGLQPVVDYA 168 Query: 183 MCAR--AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPE-PCA 235 C++ + V E M+CAG G C GDSGGPL C ++GI S+G C Sbjct: 169 TCSQRDWWGTTVKETMVCAG-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCN 227 Query: 236 LPEKPAVYTKVVHYRKWIKDTIA 258 +KP V+T+V Y WI + Sbjct: 228 TFKKPTVFTRVSAYIDWINQKLQ 250 >3F6U-H nrPDB Length = 240 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 79/250 (31%), Positives = 117/250 (46%), Gaps = 29/250 (11%) Query: 26 VGGWECEKHSQPWQVAVY-SHGWAHCGGVLVHPQWVLTAAHCLKKNSQ--VWLGRHNLFE 82 + G + PWQV + S CG VL+HP WVLTAAHC+ ++ + V LG ++L Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E + + F HP Y+ S + +D+ LL L++PA ++ + + LP Sbjct: 62 WEKWELDLDIKEVFVHPNYSKST-----------TDNDIALLHLAQPATLSQTIVPICLP 110 Query: 143 TQE------PALGTTCYASGWG----SIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKV 192 G +GWG + + R L + + ++ ++ C+ S V Sbjct: 111 DSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMV 170 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVH 248 +E MLCAG+ +D C GDSGGP+V + L G+ SWG E C L VYTKV Sbjct: 171 SENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVSR 229 Query: 249 YRKWIKDTIA 258 Y WI I Sbjct: 230 YLDWIHGHIR 239 >2R0L-A nrPDB Length = 248 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 83/251 (33%), Positives = 116/251 (46%), Gaps = 29/251 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-----KKNSQVWLGRHN 79 I+GG S PW A+Y G + C G LVH WV++AAHC + + V LG+H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP----AKITDV 135 D Q + P+ LY++ S HDL+L+RL + A + Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVF----------NPSDHDLVLIRLKKKGDRCATRSQF 109 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEK 191 V+ + LP G C +GWG ++ SL+ + L+++ C+ Y Sbjct: 110 VQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD 169 Query: 192 VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVV 247 ++ MLCAG + D C GDSGGPL C L GI SWG + C KP VYT+V Sbjct: 170 ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGVYTRVA 228 Query: 248 HYRKWIKDTIA 258 +Y WI D I Sbjct: 229 NYVDWINDRIR 239 >5XRF-A nrPDB Length = 242 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 83/239 (34%), Positives = 126/239 (52%), Gaps = 13/239 (5%) Query: 25 IVGGWECEKHSQPWQVAVY-SHGWAH-CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 ++GG EC+ + + A + S W C G L+H +WVL AAHC K+ ++LG HN Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 D QR Y + ++ D++LL+L++P + + L LP Sbjct: 67 QFDDEQRR----------YAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLP 116 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFMLCAGL 201 + P++G+ C GWG + + + P C +++LL+ C Y + T +LCAG+ Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GG DTC DSGGPL+C+G QGI +G PCA P KP +YT+V +Y WI++ IA Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGK 235 >1KYN-A nrPDB Length = 235 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 78/240 (32%), Positives = 113/240 (47%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSH---GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 I+GG E HS+P+ + G + CGG LV +VLTAAHC N V LG HN+ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 E+T Q + + HP YN ++ +D+MLL+LS + V + L Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQ-----------NDIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTQEPA--LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 P + GT C +GWG + +L+ V L + + C R + +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 G K GDSGGPL+CN V GI S+G +P P V+T+V + WI+ T+ + Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSS-GVP--PEVFTRVSSFLPWIRTTMRS 224 >3P8G-A nrPDB Length = 241 Score = 246 bits (628), Expect = 9e-66, Method: Composition-based stats. Identities = 74/251 (29%), Positives = 120/251 (47%), Gaps = 32/251 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVLTAAHCLKKN----------SQV 73 +VGG + ++ PWQV++++ G H CG L+ P W+++AAHC + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 WLGRHNLFEPEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 +LG H+ + G Q + HP +N D +D+ LL L +PA+ Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFN-----------DFTFDYDIALLELEKPAEY 109 Query: 133 TDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + +V+ + LP G + +GWG + LQ + ++ C + Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGHTQ-YGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLV---CNGVL--QGITSWGPEPCALPEKPAVYTK 245 ++T M+C G +GG D+C GDSGGPL +G + G+ SWG + CA KP VYT+ Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTR 227 Query: 246 VVHYRKWIKDT 256 + +R WIK+ Sbjct: 228 LPLFRDWIKEN 238 >1A5I-A nrPDB Length = 265 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 83/260 (31%), Positives = 121/260 (46%), Gaps = 41/260 (15%) Query: 27 GGWECEKHSQPWQVAVYSHGW------AHCGGVLVHPQWVLTAAHCLKKNS-----QVWL 75 GG + S PWQ A+++ CGG+L+ WVLTAAHC +++ +V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS----EPAK 131 GR +P + Q V H ++ D+ ++D+ LL+L + A+ Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFD-----------DDTYNNDIALLQLKSDSPQCAQ 124 Query: 132 ITDVVKVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA-- 187 +D V+ + LP L T C SG+G + L+ + L + CA Sbjct: 125 ESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFL 184 Query: 188 YSEKVTEFMLCAGLWTGGK------DTCGGDSGGPLVC----NGVLQGITSWGPEPCALP 237 +++ VT MLCAG G+ D C GDSGGPLVC + L GI SWG C Sbjct: 185 FNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEK 243 Query: 238 EKPAVYTKVVHYRKWIKDTI 257 + P VYTKV +Y WI+D + Sbjct: 244 DVPGVYTKVTNYLGWIRDNM 263 >4Q7Y-A nrPDB Length = 250 Score = 243 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 80/242 (33%), Positives = 113/242 (46%), Gaps = 20/242 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 80 I+GG E HS+P+ +V G HCGG L+ +WV++AAHC + V LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E T Q + HP Y+ ++D+ LLRL+ A + V +L Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMT-----------HANDICLLRLNGSAVLGPAVGLLR 109 Query: 141 LP---TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 197 LP + P GT C +GWG + E L P L + +L D+C ++ +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFEELPPG-LMEAKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAGLWTG-GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 C + C DSGGPLVC G+ S+ C P+ P VYT+V + WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 IA 258 + Sbjct: 229 VR 230 >2OQ5-A nrPDB Length = 232 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 113/242 (46%), Gaps = 25/242 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLFE 82 IVGG E E+ PWQ ++ G CG L++ W+++AAHC KN W + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVT- 59 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 + + + + H Y +D+ L LS P T+ V + LP Sbjct: 60 IKPSKMKRGLRRIIVHEKYK-----------HPSHDYDISLAELSSPVPYTNAVHRVCLP 108 Query: 143 --TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA--RAYSEKVTEFMLC 198 + E G + +G+G+++ + + + L+ + L+ C +AY++ +T MLC Sbjct: 109 DASYEFQPGDVMFVTGFGALKNDGYSQ-NHLRQAQVTLIDATTCNEPQAYNDAITPRMLC 167 Query: 199 AGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 AG G D C GDSGGPLV + L GI SWG E CA P KP VYT+V R WI Sbjct: 168 AGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWI 226 Query: 254 KD 255 Sbjct: 227 TS 228 >5TO3-B nrPDB Length = 409 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 77/265 (29%), Positives = 116/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE-----EFLRPRSLQCVSLHLLSN 181 +D + + LP +E A G +GWG+++ +P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 170 Query: 182 DMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC------NGVLQGITSWGPE 232 +C + ++T+ M CAG GK D C GDSGGP V GI S G Sbjct: 171 PVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA- 229 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTI 257 C K YT V +KWI+ I Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >2RDL-A nrPDB Length = 226 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 79/242 (32%), Positives = 118/242 (48%), Gaps = 22/242 (9%) Query: 25 IVGGWECEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG EC H++P+ + + + C G L+ +V+TAAHC ++ V LG HN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK--V 138 EDT Q++ V FPHP Y+ L+ +D+MLL+L E A +T V Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVL-----------NDIMLLKLKEKANLTLGVGTLP 109 Query: 139 LGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 + + G C A GWG E +LQ V + +L C + + + E LC Sbjct: 110 ISAKSNSIPPGRVCRAVGWGRTNVNEP-PSDTLQEVKMRILDPQAC-KHFEDFHQEPQLC 167 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G ++ GDSGGPL+C G+ QGI S+ + P+V+T++ HYR WI + Sbjct: 168 VGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVLRN---AKPPSVFTRISHYRPWINKILR 224 Query: 259 AN 260 N Sbjct: 225 EN 226 >2XRC-A nrPDB Length = 565 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 84/261 (32%), Positives = 114/261 (43%), Gaps = 33/261 (12%) Query: 10 LSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK 69 LS G + + + RIVGG + PWQVA+ CGG+ + W+LTAAHCL+ Sbjct: 307 LSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA 366 Query: 70 ----NSQVWLGRHNLFEPEDTGQRVP-VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 Q+W + P+ + V H YN +D+ L+ Sbjct: 367 SKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT-----------YQNDIALI 415 Query: 125 RLSEPAKITDVVKVLGLPTQEP------ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHL 178 + + D +P P TC SGWG + E + LQ + L Sbjct: 416 EMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKL 473 Query: 179 LSNDMCARAYSEKVTEF-MLCAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPE 232 +SN C++ Y + E M CAG + G D C GDSGGPLVC + G+ SWG E Sbjct: 474 ISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-E 530 Query: 233 PCALPEKPAVYTKVVHYRKWI 253 C PE P VYTKV +Y WI Sbjct: 531 NCGKPEFPGVYTKVANYFDWI 551 >4XDE-A nrPDB Length = 257 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 34/252 (13%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 +VGG + + P+ A+Y G + C G L+ P WVLTAAHCL+ + V LG+ Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK-----ITD 134 + Q + V H ++ HDL LLRL E A ++ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPV-----------SYQHDLALLRLQEDADGSCALLSP 110 Query: 135 VVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR--AYSE 190 V+ + LP+ P+ T C +GWG LQ + LS + C+ + Sbjct: 111 YVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 170 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPEKPAVY 243 + MLCAG GG D C GDSGGPLVC LQGI SWG C KP VY Sbjct: 171 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVY 229 Query: 244 TKVVHYRKWIKD 255 T V +Y WI++ Sbjct: 230 TDVAYYLAWIRE 241 >1FUJ-A nrPDB Length = 221 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 122/243 (50%), Gaps = 31/243 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHG---WAHCGGVLVHPQWVLTAAHCLKKNSQ----VWLGR 77 IVGG E + HS+P+ ++ G CGG L+HP +VLTAAHCL+ Q V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 HN+ E T Q V+ F + Y+ E+ +D++L++LS PA ++ V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDA-----------ENKLNDILLIQLSSPANLSASVA 108 Query: 138 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF 195 + LP Q+ + GT C A GWG + + + LQ +++ +++ Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVT---------FFCRPH 158 Query: 196 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 +C + C GDSGGPL+C+G++QGI S+ CA P +T+V Y WI+ Sbjct: 159 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 218 Query: 256 TIA 258 T+ Sbjct: 219 TLR 221 >4KKD-A nrPDB Length = 433 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 80/289 (27%), Positives = 120/289 (41%), Gaps = 57/289 (19%) Query: 15 TGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWA-------HCGGVLVHPQWVLTAAHCL 67 + ++P + RI+GG E PWQ + + G L+ W+LTAAH L Sbjct: 145 SRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVL 204 Query: 68 KKN-------------SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPD 114 + V+LG H++ + + HP +N+ Sbjct: 205 RSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPDFNI----------- 252 Query: 115 EDSSHDLMLLRLSEPAKITDVVKVLGLPT---QEPALGTTCYASGWGSIEPE-------- 163 ++ +HD+ L++L EP + V + LP + PA +GWG P Sbjct: 253 QNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIIS 312 Query: 164 --EFLRPRSLQCVSLHLLSNDMCARAYSEK-----VTEFMLCAGLWTGGKDTCGGDSGGP 216 LQ V L ++ + C +Y + VTE M CAG + GGKDTC GDSG Sbjct: 313 SGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEA 372 Query: 217 LV------CNGVLQGITSW-GPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 V V+QG+ SW GPE C + VYTKV +Y W+ + + Sbjct: 373 FVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 421 >1ELT-A nrPDB Length = 236 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 77/248 (31%), Positives = 114/248 (45%), Gaps = 27/248 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHG----WAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRH 78 +VGG + +S PWQ+++ + CGG L+ WV+TAAHC+ + +V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 NL E Q + V+ F H +N D +D+ LLRL+ A + V++ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSD---------DVAGGYDIALLRLNTQASLNSAVQL 111 Query: 139 LGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP L CY +GWG L SL+ L + + C+ + + V Sbjct: 112 AALPPSNQILPNNNPCYITGWGKTSTGGPL-SDSLKQAWLPSVDHATCSSSGWWGSTVKT 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWG-PEPCALPEKPAVYTKVVHY 249 M+CAG G C GDSGGPL C + G+TS+ C +KP V+T+V Y Sbjct: 171 TMVCAGG--GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAY 228 Query: 250 RKWIKDTI 257 W+ + Sbjct: 229 ISWMNGIM 236 >1FON-A nrPDB Length = 240 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 80/252 (31%), Positives = 124/252 (49%), Gaps = 30/252 (11%) Query: 27 GGWECEKHSQPWQVAVYSHG----WAHCGGVLVHPQWVLTAAHCLK--KNSQVWLGRHNL 80 G + +S WQV++ CGG L+ P WV+TA HC+ + QV LG ++ Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 81 FEPEDTGQRVPVS--HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 E + Q +P++ F HPL+N + + +D+ L++LS A++ D V++ Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCV---------ACGNDIALVKLSRSAQLGDKVQL 111 Query: 139 LGLPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVTE 194 LP L CY SGWG + L P LQ L + + C++ + V + Sbjct: 112 ANLPPAGDILPNEAPCYISGWGRLYTGGPL-PDKLQQALLPTVDYEHCSQWDWWGITVKK 170 Query: 195 FMLCAGLWTGGKDTCGGDSGGPLVC-----NGVLQGITSWGPE-PCALPEKPAVYTKVVH 248 M+CAG T + C GDSGGPL C + + G+TS+ C +KP V+T+V Sbjct: 171 TMVCAGGDT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSA 228 Query: 249 YRKWIKDTIAAN 260 + WI +TIA+N Sbjct: 229 FIDWIDETIASN 240 >3RP2-A nrPDB Length = 224 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 79/239 (33%), Positives = 115/239 (48%), Gaps = 22/239 (9%) Query: 25 IVGGWECEKHSQPWQVAV---YSHG-WAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+GG E HS+P+ + G CGG L+ Q+VLTAAHC + V LG H++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 + E T Q++ V H YN + HD+MLL+L + ++T V V+ Sbjct: 61 RKRESTQQKIKVEKQIIHESYN-----------SVPNLHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 LP+ G C+A+GWG + +L+ V L ++ C Y +F +C Sbjct: 110 LPSPSDFIHPGAMCWAAGWGKTGVRDPT-SYTLREVELRIMDEKACV-DYRYYEYKFQVC 167 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G T + GDSGGPL+C GV GI S+G + PA++T+V Y WI I Sbjct: 168 VGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYGHP---DAKPPAIFTRVSTYVPWINAVI 223 >1Q3X-A nrPDB Length = 328 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 32/265 (12%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS 71 G + RI GG + + PWQV + G G L++ WVLTAAH + + Sbjct: 76 CGLSARTTG--GRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ- 130 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPH--PLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP 129 +H+ + + + PH ++ ++ H+ D +D+ L++L+ Sbjct: 131 -----KHDASALD--IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNK 183 Query: 130 AKITDVVKVLGLPTQEPA----LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 I + + LP +E ASGWG + R+L V + ++ + C Sbjct: 184 VVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCT 241 Query: 186 RAY------SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEP 233 AY VT MLCAGL +GGKD+C GDSGG LV + GI SWG Sbjct: 242 AAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 301 Query: 234 CALPEKPAVYTKVVHYRKWIKDTIA 258 C + VYTKV++Y WI++ I+ Sbjct: 302 CGEAGQYGVYTKVINYIPWIENIIS 326 >4IGD-A nrPDB Length = 406 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 75/273 (27%), Positives = 120/273 (43%), Gaps = 42/273 (15%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLK-- 68 G + ++I G +K + PW + + +G CGG L+ W++TAAHCL Sbjct: 143 CGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQS 202 Query: 69 ----------------KNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLR 112 + ++ LG+H ++ Q + V H+ HP Y+ + + Sbjct: 203 LDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFE----- 257 Query: 113 PDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQ 172 +D+ L+ L E + V + LP G SGWG + F P +L Sbjct: 258 ------NDVALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLM 309 Query: 173 CVSLHLLSNDMCARAY---SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVL 223 + + ++ + C +AY +KVT M+CAG GGKD C GDSGGP+V L Sbjct: 310 EIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYL 369 Query: 224 QGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 G SWG + C ++ VY+ + H + WI+ Sbjct: 370 VGTVSWGDD-CGKKDRYGVYSYIHHNKDWIQRV 401 >1ZJK-A nrPDB Length = 403 Score = 233 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 76/265 (28%), Positives = 118/265 (44%), Gaps = 32/265 (12%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS 71 G + +I GG + + PWQV + G G L++ WVLTAAH + + Sbjct: 151 CGLSARTTG--GQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ- 205 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPH--PLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP 129 +H+ + + + PH ++ ++ H+ D +D+ L++L+ Sbjct: 206 -----KHDASALD--IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNK 258 Query: 130 AKITDVVKVLGLPTQEPA----LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 I + + LP +E ASGWG + R+L V + ++ + C Sbjct: 259 VVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCT 316 Query: 186 RAY------SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEP 233 AY VT MLCAGL +GGKD+C GDSGG LV + GI SWG Sbjct: 317 AAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 376 Query: 234 CALPEKPAVYTKVVHYRKWIKDTIA 258 C + VYTKV++Y WI++ I+ Sbjct: 377 CGEAGQYGVYTKVINYIPWIENIIS 401 >4BXW-A nrPDB Length = 423 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 70/254 (27%), Positives = 111/254 (43%), Gaps = 17/254 (6%) Query: 19 PLIQSRIVGGWECEKHSQPWQVAVYS-HGWAHCGGVLVHPQWVLTAAHCLKKN--SQVWL 75 P RIV G +C+ PWQ A+ CGG ++ P +VLTAAHC+ + V + Sbjct: 164 PSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVV 223 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 G + E TG + V + H + ++ +D+ ++++ P + ++ Sbjct: 224 GEIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLA--AYDYDIAIIQMKTPIQFSEN 280 Query: 136 VKVLGLPTQEPALG-----TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 V LPT + A SG+G I + + ++L+ + + + C + Sbjct: 281 VVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGP-KSKTLKVLKVPYVDRHTCMVSSET 339 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPL--VCNGV--LQGITSWGPEPCALPEKPAVYTKV 246 +T M CAG T +D C GDSGGP V + GI S G E CA K YTK+ Sbjct: 340 PITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG-EGCARNGKYGNYTKL 398 Query: 247 VHYRKWIKDTIAAN 260 + WIK + Sbjct: 399 SKFIPWIKRIMRQK 412 >4FXG-H nrPDB Length = 242 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 115/252 (45%), Gaps = 30/252 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I GG + + PWQV + G G L++ WVLTAAH + + +H+ + Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ------KHDASALD 52 Query: 85 DTGQRVPVSHSFPH--PLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 + + PH ++ ++ H+ D +D+ L++L+ I + + LP Sbjct: 53 --IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLP 110 Query: 143 TQEPA----LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY------SEKV 192 +E ASGWG + R+L V + ++ + C AY V Sbjct: 111 RKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSV 168 Query: 193 TEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEPCALPEKPAVYTKV 246 T MLCAGL +GGKD+C GD+GG LV + GI SWG C + VYTKV Sbjct: 169 TANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKV 228 Query: 247 VHYRKWIKDTIA 258 ++Y WI++ I+ Sbjct: 229 INYIPWIENIIS 240 >2XXL-A nrPDB Length = 408 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 74/266 (27%), Positives = 115/266 (43%), Gaps = 29/266 (10%) Query: 20 LIQSRIVGGWECEKHSQPWQVAVYSH----GWAHCGGVLVHPQWVLTAAHCLKKN----S 71 + R+ G+E + S+PW + CGG ++ +++LTAAHC+ Sbjct: 114 FLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLY 173 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSS--HDLMLLRLSEP 129 ++ LG H + ED Q+ P P+ N+ + KH + HD+ LL+L+ Sbjct: 174 EIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHLIHEKYDARHIMHDIALLKLNRS 232 Query: 130 AKITDVVKVLGLP-----TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 +K + LP ++ +T + +GWG+ E L ++ L C Sbjct: 233 VPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGS--SSDVLLQANVPLQPRSAC 290 Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----------NGVLQGITSWGPEPC 234 ++AY V LC G +D+C GDSGGPL V GI S G C Sbjct: 291 SQAYRRAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTC 349 Query: 235 ALPEKPAVYTKVVHYRKWIKDTIAAN 260 P +YT V Y +WI DT+A+N Sbjct: 350 GQISLPGLYTNVGEYVQWITDTMASN 375 >2ZKS-A nrPDB Length = 240 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 84/241 (34%), Positives = 119/241 (49%), Gaps = 23/241 (9%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN---SQVWLGRHNLF 81 I+GG E HS+P+ ++ +G CGGVLVHP+WVLTAAHCL + ++ LG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 P G + + HP Y +P +DL LL+L K + ++ L L Sbjct: 61 SP---GLTFHIKAAIQHPRY----------KPVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PTQEP--ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC--ARAYSEKVTEFML 197 P++ A GT C +GWG L R L+ + L +L MC +R ++ ++ M+ Sbjct: 108 PSKRQVVAAGTRCSMAGWGLTHQGGRL-SRVLRELDLQVLDTRMCNNSRFWNGSLSPSMV 166 Query: 198 CAGLWTGGKDTCGGDSGGPLVC--NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 C + + C GDSGGPLVC VL G+ S+ C KP V T V Y WI+ Sbjct: 167 CLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 226 Query: 256 T 256 Sbjct: 227 V 227 >4IW4-E nrPDB Length = 279 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 79/279 (28%), Positives = 115/279 (41%), Gaps = 57/279 (20%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA-------HCGGVLVHPQWVLTAAHCLKKN------- 70 I+GG E PWQ + + G L+ W+LTAAH L+ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 71 ------SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 V+LG H++ + + HP +N+ ++ +HD+ L+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPDFNI-----------QNYNHDIALV 108 Query: 125 RLSEPAKITDVVKVLGLPT---QEPALGTTCYASGWGSIEPE----------EFLRPRSL 171 +L EP + V + LP + PA +GWG P L Sbjct: 109 QLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVL 168 Query: 172 QCVSLHLLSNDMCARAYSEK-----VTEFMLCAGLWTGGKDTCGGDSGGPLV------CN 220 Q V L ++ + C +Y + VTE M CAG + GGKDTC GDSGG V Sbjct: 169 QYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQR 228 Query: 221 GVLQGITSW-GPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 V+QG+ SW GPE C + VYTKV +Y W+ + + Sbjct: 229 WVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 267 >4DJZ-B nrPDB Length = 251 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 116/260 (44%), Gaps = 42/260 (16%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLK--------------- 68 I G +K + PW + + +G CGG L+ W++TAAHCL Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 69 ---KNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125 + ++ LG+H ++ Q + V H+ HP Y+ + + +D+ L+ Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFE-----------NDVALVE 109 Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 L E + V + LP G SGWG + F P +L + + ++ + C Sbjct: 110 LLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDHSTCQ 167 Query: 186 RAY---SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC------NGVLQGITSWGPEPCAL 236 +AY +KVT M+CAG GGKD C GDSGGP+V L G SWG + C Sbjct: 168 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGK 226 Query: 237 PEKPAVYTKVVHYRKWIKDT 256 ++ VY+ + H + WI+ Sbjct: 227 KDRYGVYSYIHHNKDWIQRV 246 >5UBM-A nrPDB Length = 252 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 112/260 (43%), Gaps = 37/260 (14%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN--SQVWLGRHNLF 81 RI+GG + + + PWQV + + WA GG L++ WVLTAAH ++ N +++G ++ Sbjct: 1 RIIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 82 EPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 ++ H F HP + + + + +D+ L+RL +P K+ V + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGR----TNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 141 LPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK----- 191 LP G SGWG E + R L+ L + C EK Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 ----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGITSWGPEPCALPEKP 240 T M+CAG G D+C GDSGG G+ SWGP+ C Sbjct: 172 EAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 241 AVYTKVVHYRKWIKDTIAAN 260 +YT+V +Y WI T+ N Sbjct: 227 GLYTRVKNYVDWIMKTMQEN 246 >1ELV-A nrPDB Length = 333 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 39/273 (14%) Query: 12 VGCTGAVPLI-QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70 G P + RI+GG + + + PWQV + + WA GG L++ WVLTAAH ++ N Sbjct: 70 CGVP-REPFEEKQRIIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGN 125 Query: 71 --SQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 +++G ++ ++ H F HP + + + + +D+ L+RL Sbjct: 126 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGR----TNFDNDIALVRLK 181 Query: 128 EPAKITDVVKVLGLPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183 +P K+ V + LP G SGWG E + R L+ L + Sbjct: 182 DPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRK 239 Query: 184 CARAYSEK---------VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGIT 227 C EK T M+CAG G D+C GDSGG G+ Sbjct: 240 CKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLV 298 Query: 228 SWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 SWGP+ C +YT+V +Y WI T+ N Sbjct: 299 SWGPQ-CGT---YGLYTRVKNYVDWIMKTMQEN 327 >5O32-I nrPDB Length = 244 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 80/246 (32%), Positives = 107/246 (43%), Gaps = 33/246 (13%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK----NSQVWLGRHNL 80 IVGG + PWQVA+ CGG+ + W+LTAAHCL+ Q+W + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 81 FEPEDTGQRVP-VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 P+ + V H YN +D+ L+ + + D Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGT-----------YQNDIALIEMKKDGNKKDCELPR 109 Query: 140 GLPTQEP------ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193 +P P TC SGWG + E + LQ + L+SN C++ Y + Sbjct: 110 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY 165 Query: 194 EF-MLCAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVV 247 E M CAG + G D C GDSGGPLVC + G+ SWG E C PE P VYTKV Sbjct: 166 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVA 224 Query: 248 HYRKWI 253 +Y WI Sbjct: 225 NYFDWI 230 >5KWM-A nrPDB Length = 230 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 83/243 (34%), Positives = 113/243 (46%), Gaps = 27/243 (11%) Query: 25 IVGGWECEKHSQPWQVAVYS-HGWAHCGGVLVHPQWVLTAAHCL----KKNSQVWLGRHN 79 IVGG + P+ VA+ + G CGG L P V+TAAHC + V GR Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 + E T + V++ + HP Y D D+ +L L P K + Sbjct: 61 MSSNEGTVSK--VTNVWVHPEY-----------QDAAKGFDVSVLTLEAPVKE----API 103 Query: 140 GLPTQE---PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM 196 L + A T GWG+ + LQ ++ + S+D C +AY E + M Sbjct: 104 ELAKADDAGYAPDTAATILGWGNTSE-GGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM 162 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 +CAG+ GG DTC GDSGGP+V N L G+TSWG E CA P KP VY +V Y + + Sbjct: 163 VCAGVPEGGVDTCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYDVLMEQ 221 Query: 257 IAA 259 I A Sbjct: 222 INA 224 >1YM0-A nrPDB Length = 238 Score = 218 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 74/251 (29%), Positives = 113/251 (45%), Gaps = 28/251 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW--AHCGGVLVHPQWVLTAAHCLKKN----SQVWLGRH 78 IVGG E + PWQV+V CGG +++ +WV+ AAHC++ + +G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 + Q V F + Y+ + L+ +D+ +++ + V Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLE-----------NDVSVIKTAVAITFDINVGP 109 Query: 139 LGLPT-QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFM 196 + P + SGWG+I P L+ V+L++ +N C Y S+ + + M Sbjct: 110 ICAPDPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDM 169 Query: 197 LCAGLWTG--GKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHY 249 +CA TG +D+C GDSGGPL L GI SWG CA P VY++V + Sbjct: 170 ICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCA-SGYPGVYSRVGFH 227 Query: 250 RKWIKDTIAAN 260 WI DTI N Sbjct: 228 AGWITDTITNN 238 >1GPZ-A nrPDB Length = 399 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 73/260 (28%), Positives = 106/260 (40%), Gaps = 39/260 (15%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK---------KNSQ 72 + +I+GG + + + PWQV HG GG L+ +W+LTAAH L + Sbjct: 155 RQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 212 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 V+LG N+ E G P+ HP Y + D+ LL L + Sbjct: 213 VFLGHTNVEELMKLG-NHPIRRVSVHPDYRQD--------ESYNFEGDIALLELENSVTL 263 Query: 133 TDVVKVLGLPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + + LP + LG Y SG+G +E + L+ V L + + C Sbjct: 264 GPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRG 320 Query: 191 K-----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEK 239 K ++ M CAG + +D C GDSGG V GI SWG C+ Sbjct: 321 KNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG-- 377 Query: 240 PAVYTKVVHYRKWIKDTIAA 259 YTKV++Y WIK + Sbjct: 378 YGFYTKVLNYVDWIKKEMEE 397 >4J1Y-A nrPDB Length = 397 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 75/273 (27%), Positives = 115/273 (42%), Gaps = 39/273 (14%) Query: 12 VGCTGAVPLI-QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70 G P ++R +GG + + + PWQV + + WA GG L++ WVLTAAH ++ N Sbjct: 134 CGVP-REPFEEKARAIGGSDADIKNFPWQV-FFDNPWA--GGALINEYWVLTAAHVVEGN 189 Query: 71 --SQVWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 +++G ++ ++ H F HP + + + + +D+ L+RL Sbjct: 190 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGR----TNFDNDIALVRLK 245 Query: 128 EPAKITDVVKVLGLPTQEPAL----GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183 +P K+ V + LP G SGWG E + R L+ L + Sbjct: 246 DPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRD--RAVRLKAARLPVAPLRK 303 Query: 184 CARAYSEK---------VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-------VLQGIT 227 C EK T M+CAG G D+C GDSGG G+ Sbjct: 304 CKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLV 362 Query: 228 SWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 SWGP+ C +YT+V +Y WI T+ N Sbjct: 363 SWGPQ-CGT---YGLYTRVKNYVDWIMKTMQEN 391 >2OLG-A nrPDB Length = 278 Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats. Identities = 71/261 (27%), Positives = 120/261 (45%), Gaps = 29/261 (11%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAH-----CGGVLVHPQWVLTAAHCLKKN------- 70 +I+ G + PW + ++ CGG L++ ++++TAAHC+ Sbjct: 21 DKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGA 80 Query: 71 -SQVWLGRHNL-FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSL-RPDEDSSHDLMLLRLS 127 ++V LG N +P+ G P L ++H +D HD+ L+RL+ Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLN 140 Query: 128 EPAKITDVVKVLGL--PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 + T+ ++ + L P +E +G GWG E ++ + Q +++ ++ + CA Sbjct: 141 RQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK--QKLAVPVVHAEQCA 198 Query: 186 RAYSE---KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALP 237 + + +V LCAG KD+CGGDSGGPL+ L+G+ S+G C Sbjct: 199 KTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGAT-CGTE 256 Query: 238 EKPAVYTKVVHYRKWIKDTIA 258 P +YTKV YR WI+ I Sbjct: 257 GWPGIYTKVGKYRDWIEGNIR 277 >1MD7-A nrPDB Length = 328 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 106/258 (41%), Gaps = 39/258 (15%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK---------KNSQ 72 + RI+GG + + + PWQV HG GG L+ +W+LTAAH L + Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 73 VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 132 V+LG N+ E G P+ HP Y + D+ LL L + Sbjct: 145 VFLGHTNVEELMKLG-NHPIRRVSVHPDYRQD--------ESYNFEGDIALLELENSVTL 195 Query: 133 TDVVKVLGLPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 + + LP + LG Y SG+G +E + L+ V L + + C Sbjct: 196 GPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRG 252 Query: 191 K-----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEK 239 K ++ M CAG + +D C GD+GG V GI SWG C+ Sbjct: 253 KNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI-GCSRG-- 309 Query: 240 PAVYTKVVHYRKWIKDTI 257 YTKV++Y WIK + Sbjct: 310 YGFYTKVLNYVDWIKKEM 327 >1AE5-A nrPDB Length = 225 Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats. Identities = 72/243 (29%), Positives = 112/243 (46%), Gaps = 29/243 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS----QVWLGRHNL 80 IVGG + P+ ++ + G CGG L+H ++V+TAA C + + V LG ++L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E ++ +++S + P ++ +DLMLL+L A +T V +L Sbjct: 61 RRRERQSRQ----------TFSISSMSENGYDPQQNL-NDLMLLQLDREANLTSSVTILP 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 LP Q + GT C +GWGS L R + V++ + D C +C Sbjct: 110 LPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNVC 160 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 G+ T C GD G PLVC G+ G+ S+ PC P +T+V +R WI + Sbjct: 161 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL- 217 Query: 259 ANP 261 NP Sbjct: 218 NNP 220 >2QY0-B nrPDB Length = 242 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 104/257 (40%), Gaps = 39/257 (15%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK---------KNSQVWL 75 I+GG + + + PWQV HG GG L+ +W+LTAAH L + V+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 76 GRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 G N+ E G P+ HP Y + D+ LL L + Sbjct: 59 GHTNVEELMKLG-NHPIRRVSVHPDYRQD--------ESYNFEGDIALLELENSVTLGPN 109 Query: 136 VKVLGLPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-- 191 + + LP + LG Y SG+G +E + L+ V L + + C K Sbjct: 110 LLPICLPDNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNR 166 Query: 192 ---VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPCALPEKPAV 242 ++ M CAG + +D C GDSGG V GI SWG C+ Sbjct: 167 MDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGF 223 Query: 243 YTKVVHYRKWIKDTIAA 259 YTKV++Y WIK + Sbjct: 224 YTKVLNYVDWIKKEMEE 240 >1EQ9-A nrPDB Length = 222 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 114/241 (47%), Gaps = 25/241 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79 IVGG + P+QV++ G CG ++ VLTAAHC+ +V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L E +G V + + Y+ LL+ +D+ L+ L+ P K D+V+ + Sbjct: 61 LSE---SGDVYDVEDAVVNKNYDDFLLR-----------NDVALVHLTNPIKFNDLVQPI 106 Query: 140 GLPTQEPALGT-TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 L T + L + C +GWGS P +LQ + L + C R +V + +C Sbjct: 107 KLSTNDEDLESNPCTLTGWGSTRL-GGNTPNALQEIELIVHPQKQCERD-QWRVIDSHIC 164 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 L G+ C GDSGGPLV NG GI S+G PCAL E P VYT+V + WI + Sbjct: 165 T-LTKRGEGACHGDSGGPLVANGAQIGIVSFGS-PCALGE-PDVYTRVSSFVSWINANLK 221 Query: 259 A 259 Sbjct: 222 K 222 >2PKA-B nrPDB Length = 152 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 98/149 (65%), Positives = 110/149 (73%), Gaps = 2/149 (1%) Query: 115 EDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPE--EFLRPRSLQ 172 +D SHDLMLLRL PAKITD VKVL LPTQEP LG+TC ASGWGSIEP +F P +Q Sbjct: 4 KDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEIQ 63 Query: 173 CVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPE 232 CV L LL N CA A+ +KVTE MLCAG GGKDTC GDSGGPL+CNG+ QGITSWG Sbjct: 64 CVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHT 123 Query: 233 PCALPEKPAVYTKVVHYRKWIKDTIAANP 261 PC KP++YTK++ Y WI DTI NP Sbjct: 124 PCGSANKPSIYTKLIFYLDWIDDTITENP 152 >1PPF-E nrPDB Length = 218 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 107/240 (44%), Gaps = 28/240 (11%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVW----LGRHNL 80 IVGG H+ P+ V++ G CG L+ P +V++AAHC+ + LG HNL Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 E T Q V F ++ + +D+++L+L+ A I V+V Sbjct: 61 SRREPTRQVFAVQRIF------------ENGYDPVNLLNDIVILQLNGSATINANVQVAQ 108 Query: 141 LPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 LP Q LG C A GWG + + LQ +++ +++ +C R+ +C Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLGRNRGIAS-VLQELNVTVVT-SLCRRS--------NVC 158 Query: 199 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258 + C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 159 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1PQ7-A nrPDB Length = 224 Score = 209 bits (533), Expect = 8e-55, Method: Composition-based stats. Identities = 72/238 (30%), Positives = 106/238 (44%), Gaps = 25/238 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK----NSQVWLGRHNL 80 IVGG P+ V++ +G CGG L++ VLTAAHC+ Q+ G + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 G +S HP Y+ +++DL +L+LS + Sbjct: 61 TS---GGITSSLSSVRVHPSYS-------------GNNNDLAILKLSTSIPSGGNIGYAR 104 Query: 141 LPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKVTEFML 197 L +P G++ +GWG+ P +L V++ ++S C Y +T M Sbjct: 105 LAASGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMF 164 Query: 198 CAGLWTGGKDTCGGDSGGPLV-CNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254 CAG+ +GGKD+C GDSGGP+V + L G SWG CA P VY V R +I Sbjct: 165 CAGVSSGGKDSCQGDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFID 221 >6BQM-A nrPDB Length = 506 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 111/268 (41%), Gaps = 47/268 (17%) Query: 15 TGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCLKKNS- 71 +G + SRI+GG + P+ VA+ + + CGG + ++VLTAAHC+ K Sbjct: 1 SGTESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDP 60 Query: 72 ---QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS- 127 V LG ++ + +T +R+ V + H Y + + +D+ +L L Sbjct: 61 AKGDVLLGAFDMNDV-NTAERIHVRQIYVHNSYITASM-----------GNDIAVLELER 108 Query: 128 -----EPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPR---SLQCVSLHLL 179 +I+D L P G+G+ + + + L V + + Sbjct: 109 DPLPRRSVQISDSSDFNELTKDSP-----MTVIGFGNRKEVDGEKSDPATILHQVQVPFV 163 Query: 180 SNDMCA--------RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ-GIT 227 C + ++T CAG + GKD C GD+GGP+ NG Q G+ Sbjct: 164 PLPECKTKGSDQDAKNNYSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVV 221 Query: 228 SWGPEPCALPEKPAVYTKVVHYRKWIKD 255 SWG + C P VYT + + W+ D Sbjct: 222 SWG-DGCGRANSPGVYTNLSVFNDWLDD 248 >4X0L-C nrPDB Length = 259 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 73/277 (26%), Positives = 106/277 (38%), Gaps = 47/277 (16%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL---- 67 G RI+GG K S PWQ + SH G L++ QW+LT A L Sbjct: 2 CGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNH 61 Query: 68 KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 +N+ L Q V + HP Y+ D+ L++L Sbjct: 62 SENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLK 106 Query: 128 EPAKITDVVKVLGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR 186 + + + V + LP+++ A +G Y SGWG F L+ V L + D C R Sbjct: 107 QKVSVNERVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIR 164 Query: 187 AYSE-----------------KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VL 223 Y + E CAG+ +DTC GD+G + Sbjct: 165 HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYA 224 Query: 224 QGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GI S+ + CA+ E VY KV + W++ TIA N Sbjct: 225 TGILSF-DKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 259 >2B9L-A nrPDB Length = 394 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 74/282 (26%), Positives = 102/282 (36%), Gaps = 47/282 (16%) Query: 12 VGCTGAVPLIQSRIVGGW-ECEKHSQPWQVAVYSHG--------WAHCGGVLVHPQWVLT 62 G + +I G E E PW VAV CGG L+ P VLT Sbjct: 118 CGIRNER-GLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLT 176 Query: 63 AAHCLKKN------SQVWLGRHNLFEPED--TGQRVPVSHSFPHPLYNMSLLKHQSLRPD 114 AHC+ ++ G + ++ Q + H +N + Sbjct: 177 GAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVV------- 229 Query: 115 EDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTT-CYASGWGSIEPEEF-LRPRSLQ 172 +D+ LL L P D + + LP Q +T C+ASGWG E L+ Sbjct: 230 ----NDVALLLLDRPLVQADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILK 285 Query: 173 CVSLHLLSNDMCARAYSEK-------VTEFMLCAGLWTGGKDTCGGDSGGPLVC------ 219 + L + D C + + +CAG GKDTC GD G PL C Sbjct: 286 KIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNP 344 Query: 220 -NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 + GI +WG C P VY V H+R WI + A Sbjct: 345 SRYMQMGIVAWGI-GCGDENVPGVYANVAHFRNWIDQEMQAK 385 >4WJG-C nrPDB Length = 315 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 73/277 (26%), Positives = 106/277 (38%), Gaps = 47/277 (16%) Query: 12 VGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL---- 67 G RI+GG K S PWQ + SH G L++ QW+LT A L Sbjct: 58 CGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNH 117 Query: 68 KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127 +N+ L Q V + HP Y+ D+ L++L Sbjct: 118 SENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLK 162 Query: 128 EPAKITDVVKVLGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCAR 186 + + + V + LP+++ A +G Y SGWG F L+ V L + D C R Sbjct: 163 QKVSVNERVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIR 220 Query: 187 AYSE-----------------KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VL 223 Y + E CAG+ +DTC GD+G + Sbjct: 221 HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYA 280 Query: 224 QGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GI S+ + CA+ E VY KV + W++ TIA N Sbjct: 281 TGILSF-DKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 315 >4LK4-A nrPDB Length = 357 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 74/251 (29%), Positives = 103/251 (41%), Gaps = 30/251 (11%) Query: 21 IQSRIVGGWECEKHSQPWQVAVYSHG-----WAHCGGVLVHPQWVLTAAHCLKKN----S 71 I SRI+ G P VA+ G CGG + ++VLTAAHC Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 72 QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G ++L G+R+ + H Y+ S L + + + L + L+ PA Sbjct: 67 DVIIGAYDLN-NSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLAGPAT 125 Query: 132 ITDVVKVLGLPTQEPALGTTCYASGWGSI-EPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 T LP T +GWG + + LQ V + L+S +C Sbjct: 126 RTS------LPAL-----TPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQH 174 Query: 191 KV----TEFMLCAGLWTGGKDTCGGDSGGPLVCN-GVLQ-GITSWGPEPCALPEKPAVYT 244 + CA T KD+C GD+GGP+V G Q GI SWG E CA VYT Sbjct: 175 GISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYT 232 Query: 245 KVVHYRKWIKD 255 V ++R WI Sbjct: 233 NVSYFRDWITK 243 >3I77-A nrPDB Length = 230 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 100/244 (40%), Gaps = 32/244 (13%) Query: 25 IVGGWECEKHSQPWQVAV-YSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +VGG + P+ V + CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVS-------GSGNNTSI 53 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 TG V + S + + +L+ E D L++L++ + PT Sbjct: 54 TATGGVVDLQSSSAVKVRSTKVLQAPGF-TKETYGKDWALIKLAQ---------PINQPT 103 Query: 144 QEPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFML 197 + A T T +GWG+ E + R L ++ +S+ C + S V M+ Sbjct: 104 LKIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMI 162 Query: 198 CAGLWT-GGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRK 251 CAG GG DTC GDSGGP+ + GI SWG CA P P VYT+V + Sbjct: 163 CAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFAS 221 Query: 252 WIKD 255 I Sbjct: 222 AIAS 225 >2ASU-B nrPDB Length = 234 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 102/249 (40%), Gaps = 38/249 (15%) Query: 25 IVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKK------NSQVWLGR 77 +VGG + PW V++ + G CGG LV QW+LTA C +VWLG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 78 H--NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDV 135 N E + QRVPV+ P L+LL+L + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPS-----------------GSQLVLLKLERSVTLNQR 100 Query: 136 VKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193 V ++ LP + + GT C +GWG + L L+++SN C + +V Sbjct: 101 VALICLPPEWYVVPPGTKCEIAGWGETKGTG--NDTVLNVALLNVISNQECNIKHRGRVR 158 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVVHY 249 E +C C GD GGPL C + VL+GI CA PAV+T+V + Sbjct: 159 ESEMCTEGLLAPVGACEGDYGGPLACFTHNSWVLEGIII-PNRVCARSRWPAVFTRVSVF 217 Query: 250 RKWIKDTIA 258 WI + Sbjct: 218 VDWIHKVMR 226 >1SI5-H nrPDB Length = 240 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 107/249 (42%), Gaps = 39/249 (15%) Query: 25 IVGG--WECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRH 78 +V G W V++ CGG L+ WVLTA C K+ + WLG H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 79 NL--FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 136 ++ E Q + VS P DL+L++L+ PA + D V Sbjct: 58 DVHGRGDEKCKQVLNVSQLVYGPE-----------------GSDLVLMKLARPAVLDDFV 100 Query: 137 KVLGLPTQEPALG--TTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT- 193 + LP + T+C GWG L+ L+++ N+ C++ + KVT Sbjct: 101 STIDLPNYGSTIPEKTSCSVYGWGYT--GLINYDGLLRVAHLYIMGNEKCSQHHRGKVTL 158 Query: 194 -EFMLCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWGPEPCALPEKPAVYTKVVH 248 E +CAG G C GD GGPLVC ++ G+ G CA+P +P ++ +V + Sbjct: 159 NESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPG-RGCAIPNRPGIFVRVAY 217 Query: 249 YRKWIKDTI 257 Y KWI I Sbjct: 218 YAKWIHKII 226 >3BEU-A nrPDB Length = 224 Score = 196 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 71/242 (29%), Positives = 100/242 (41%), Gaps = 34/242 (14%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG + P+ V + CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 TG V + S + + +L+ E D L++L++ + PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQAPGF-TKETYGKDWALIKLAQ---------PINQPTL 99 Query: 145 EPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFMLC 198 + A T T +GWG+ E + R L ++ +S+ C + S V M+C Sbjct: 100 KIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMIC 158 Query: 199 AGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 AG T +DTC GDSGGP+ V GI SWG E CA K VYT+V + I Sbjct: 159 AGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWG-EGCARKGKYGVYTEVSTFASAI 217 Query: 254 KD 255 Sbjct: 218 AS 219 >4F4O-C nrPDB Length = 347 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 68/266 (25%), Positives = 103/266 (38%), Gaps = 47/266 (17%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL----KKNSQVWLGRH 78 RI+GG K S PWQ + SH G L++ QW+LT A L K +++ Sbjct: 101 QRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAP 160 Query: 79 NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKV 138 L Q V + HP ++S+ D+ L++L + + + V Sbjct: 161 TLRLYVGKKQEVEIEKVIFHP---------------DNSTVDIGLIKLKQKVPVNERVMP 205 Query: 139 LGLPTQEPA-LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE------- 190 + LP+++ +G Y SGWG L+ V L + + C + Y Sbjct: 206 ICLPSKDYVNVGLVGYVSGWGR--NANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKK 263 Query: 191 ----------KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG------VLQGITSWGPEPC 234 + E CAGL +DTC GD+G + GI S+ + C Sbjct: 264 TPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSF-DKSC 322 Query: 235 ALPEKPAVYTKVVHYRKWIKDTIAAN 260 E VY +V WI+ TIA N Sbjct: 323 RTAE-YGVYVRVTSILDWIQTTIADN 347 >2HLC-A nrPDB Length = 230 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 29/243 (11%) Query: 25 IVGGWECEKHSQPWQV----AVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 80 I+ G+E P+Q + CGG L+ +W+LTAAHC+ V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 + E V H ++N + +D+ L+++ + TD ++ + Sbjct: 61 VQYEGEA-VVNSERIISHSMFNP-----------DTYLNDVALIKIPH-VEYTDNIQPIR 107 Query: 141 LPTQEPALGTT----CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS-EKVTEF 195 LP+ E SGWG + + LQ ++ ND CA+ Y + E Sbjct: 108 LPSGEELNNKFENIWATVSGWGQSNTDTVI----LQYTYNLVIDNDRCAQEYPPGIIVES 163 Query: 196 MLCAGLWTGGKDTCGGDSGGPLVCNG--VLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 +C G + GK C GDSGGP V + +L G+ S+ KP +++V Y WI Sbjct: 164 TIC-GDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWI 222 Query: 254 KDT 256 + Sbjct: 223 QQN 225 >2FMJ-A nrPDB Length = 222 Score = 193 bits (491), Expect = 6e-50, Method: Composition-based stats. Identities = 71/242 (29%), Positives = 101/242 (41%), Gaps = 36/242 (14%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 +VGG + P+ V + CGG L VLTAAHC+ G N Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 144 TG V + S + + +L+ + D L++L++ + PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQAPGYN---GTGKDWALIKLAQ---------PINQPTL 97 Query: 145 EPALGT-----TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-VTEFMLC 198 + A T T +GWG+ E + R L ++ +S+ C AY + V +C Sbjct: 98 KIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEIC 156 Query: 199 AGLWTGGKDTCGGDSGGPLVCNG-----VLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 AG TGG DTC GDSGGP+ + GI SWG E CA K VYT+V + I Sbjct: 157 AGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-EGCARKGKYGVYTEVSTFASAI 215 Query: 254 KD 255 Sbjct: 216 AS 217 >3H7T-A nrPDB Length = 235 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 56/244 (22%), Positives = 96/244 (39%), Gaps = 21/244 (8%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GG + + +PW V V CGG ++ +V+TAA C+ + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 85 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITD-VVKVLGLPT 143 T ++ Y+ ++ ++ ++ P K+ D K + LP+ Sbjct: 61 TTKGTSVMAKKIYIVRYHPLTMQ-----------NNYAVIETEMPIKLDDKTTKKIELPS 109 Query: 144 --QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK-----VTEFM 196 +P T+ SGWGS + L + ++ C Y + + + + Sbjct: 110 LLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGV 169 Query: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256 CAG GD+G P V NG L G+ S+ E P+V+ +V +Y IKD Sbjct: 170 FCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSM--PSEFPSVFLRVGYYVLDIKDI 227 Query: 257 IAAN 260 I+ Sbjct: 228 ISGK 231 >5XW8-A nrPDB Length = 133 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 12/139 (8%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 +IVGG+ C +S P+QV++ S G CGG L++ QWV++AAHC K QV LG HN+ Sbjct: 7 DKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E Q + + HP +N + L +D+ML++LS PA + V + LP Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSSPATLNSRVATVSLP 114 Query: 143 TQEPALGTTCYASGWGSIE 161 A GT C SGWG+ + Sbjct: 115 RSCAAAGTECLISGWGNTK 133 >1M9U-A nrPDB Length = 241 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 99/252 (39%), Gaps = 32/252 (12%) Query: 25 IVGGWECEKHSQPWQVAVYSHGW---AHCGGVLVHPQWVLTAAHCLKK----NSQVWLGR 77 ++GG PWQ++ CG L+ L+A+HC+ N +V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 78 HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137 + T Q V H Y S+D+ +L L+ + ++ Sbjct: 61 WQQSDTSGT-QTANVDSYTMHENYGAGT---------ASYSNDIAILHLATSISLGGNIQ 110 Query: 138 VLGLPTQEPA--LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY----SEK 191 LP GTTC SGWG + L P LQ S+ +++ C A Sbjct: 111 AAVLPANNNNDYAGTTCVISGWGRTDGTNNL-PDILQKSSIPVITTAQCTAAMVGVGGAN 169 Query: 192 VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG---VLQGITSW----GPEPCALPEKPAVYT 244 + + +C G C GDSGGPL C + G+TSW G C LP+ P+VYT Sbjct: 170 IWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYT 228 Query: 245 KVVHYRKWIKDT 256 +V Y WI D Sbjct: 229 RVSAYLGWIGDN 240 >3H7O-A nrPDB Length = 228 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 68/244 (27%), Positives = 100/244 (40%), Gaps = 27/244 (11%) Query: 27 GGWECEKHSQPWQVAVYS---HGWAHCGGVLVHPQWVLTAAHCL--KKNSQVWLGRHNLF 81 GG + + PW VAV + CGG ++ +VLTAAHC+ +K + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI-TDVVKVLG 140 ED G+ P H + S E +D+ +L LS P K+ K Sbjct: 62 LWEDPGKSDP---YVSH--------VYLSFYRQETMENDIAILELSRPLKLDGLKSKPAK 110 Query: 141 LPTQE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM-L 197 LP E P G+ SG+G + + + L+ L ++ D C Y Sbjct: 111 LPDIEFRPKTGSDVLVSGYGDGQTMDP-KDHDLKSAQLTVVDLDECRTKYGPIFLSLQVF 169 Query: 198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEK-PAVYTKVVHYRKWIKDT 256 CA G GD+G P V L G+ ++ P+ PE P V+TKV Y WI+D Sbjct: 170 CA--QKVGVSLESGDAGDPTVQQDTLVGVAAYFPK---RPEGAPEVFTKVGSYVSWIQDI 224 Query: 257 IAAN 260 I Sbjct: 225 IKKK 228 >1AKS-B nrPDB Length = 98 Score = 153 bits (387), Expect = 7e-38, Method: Composition-based stats. Identities = 52/99 (52%), Positives = 62/99 (62%), Gaps = 1/99 (1%) Query: 162 PEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNG 221 P LQC+ +LSN C +Y ++T M+C G GGKD+C GDSGGP+VCNG Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 222 VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 LQGI SWG CA KP VYTKV +Y WI+ TIAAN Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >3VGC-B nrPDB Length = 131 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 15/141 (10%) Query: 25 IVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFE 82 IV G E S PWQV++ G+ CGG L++ WV+TAAHC + + V G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 + Q++ ++ F + YN + ++D+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTI-----------NNDITLLKLSTAASFSQTVSAVCLP 109 Query: 143 TQ--EPALGTTCYASGWGSIE 161 + + A GTTC +GWG Sbjct: 110 SASDDFAAGTTCVTTGWGLTR 130 >1RIW-B nrPDB Length = 147 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 28/157 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 V +G+H+ E +++ + + HP YN E+ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE 163 +D + + LP +E A G +GWG+++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET 147 >2JET-B nrPDB Length = 128 Score = 150 bits (379), Expect = 6e-37, Method: Composition-based stats. Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 15/138 (10%) Query: 28 GWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFEPED 85 G + S PWQV++ G+ CGG L+ WV+TAAHC +K + V G + E+ Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 86 TGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP--T 143 Q + ++ F +P +NM ++ +D+ LL+L+ PA+ ++ V + LP Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVR-----------NDITLLKLATPAQFSETVSAVCLPNVD 109 Query: 144 QEPALGTTCYASGWGSIE 161 + GT C +GWG + Sbjct: 110 DDFPPGTVCATTGWGKTK 127 >2I6S-A nrPDB Length = 517 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 61/250 (24%), Positives = 94/250 (37%), Gaps = 50/250 (20%) Query: 26 VGGWECEKHSQ---PWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 VG Q PW V + C G L+ QWVLTAAHC + + L R N+ + Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 289 Query: 83 P-EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 P G+ + + P +++ K+Q + E D+ LL+L++ K++ + + L Sbjct: 290 PKSQWGKEFLIEKAVISPGFDVFAKKNQGIL--EFYGDDIALLKLAQKVKMSTHARPICL 347 Query: 142 PTQEPA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSND------------ 182 P A G+TC E L +S+ + L + Sbjct: 348 PCTMEANLALRRPQGSTC------RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWT 401 Query: 183 MCARA-------------YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVL----QG 225 CA E VT+ LC+G + C G+SGG + G Sbjct: 402 SCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVG 460 Query: 226 ITSWG-PEPC 234 + SWG PC Sbjct: 461 LVSWGLYNPC 470 >1BBR-H nrPDB Length = 150 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 28/157 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL-----KKNSQV---- 73 IV G + E PWQV ++ CG L+ +WVLTAAHCL KN V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 74 -WLGRHNLFEPEDTGQRVPV-SHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131 +G+H+ E +++ + + HP YN E+ D+ LL+L P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNW----------KENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKVLGLPTQEPA-----LGTTCYASGWGSIEPE 163 ++D + + LP ++ A G +GWG+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2WIN-I nrPDB Length = 507 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 66/282 (23%), Positives = 106/282 (37%), Gaps = 66/282 (23%) Query: 31 CEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDT 86 + H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGG 284 Query: 87 GQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQE 145 +R + + HP YN++ K + E +D+ L++L K ++ + LP E Sbjct: 285 EKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 342 Query: 146 PA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSL----HLLSNDM----------- 183 TTC + EE L + ++ + + L+ Sbjct: 343 GTTRALRLPPTTTCQ------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 396 Query: 184 CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG----VLQG 225 C R SE VT LC G + D TC GDSGGPL+ + + G Sbjct: 397 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 456 Query: 226 ITSWG-PEPC----ALPEKP----AVYTKVVHYRKWIKDTIA 258 + SWG + C + P + + W+K+ + Sbjct: 457 VISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >1DLE-A nrPDB Length = 298 Score = 139 bits (352), Expect = 9e-34, Method: Composition-based stats. Identities = 66/282 (23%), Positives = 106/282 (37%), Gaps = 66/282 (23%) Query: 31 CEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDT 86 + H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGG 77 Query: 87 GQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQE 145 +R + + HP YN++ K + E +D+ L++L K ++ + LP E Sbjct: 78 EKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 135 Query: 146 PA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSL----HLLSNDM----------- 183 TTC + EE L + ++ + + L+ Sbjct: 136 GTTRALRLPPTTTCQ------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 189 Query: 184 CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG----VLQG 225 C R SE VT LC G + D TC GDSGGPL+ + + G Sbjct: 190 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 249 Query: 226 ITSWG-PEPC----ALPEKP----AVYTKVVHYRKWIKDTIA 258 + SWG + C + P + + W+K+ + Sbjct: 250 VISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2OK5-A nrPDB Length = 752 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 66/282 (23%), Positives = 106/282 (37%), Gaps = 66/282 (23%) Query: 31 CEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDT 86 + H QPWQ + S G C G +V +VLTAAHC + + H++ Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGG 528 Query: 87 GQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQE 145 +R + + HP YN++ K + E +D+ L++L K ++ + LP E Sbjct: 529 EKRDLEIEVVLFHPNYNINGKKEAGI--PEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 586 Query: 146 PA-------LGTTCYASGWGSIEPEEFLRPRSLQCVSL----HLLSNDM----------- 183 TTC + EE L + ++ + + L+ Sbjct: 587 GTTRALRLPPTTTCQ------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 640 Query: 184 CAR------------AYSEKVTEFMLCAGLWTGGKD--TCGGDSGGPLVCNG----VLQG 225 C R SE VT LC G + D TC GDSGGPL+ + + G Sbjct: 641 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 700 Query: 226 ITSWG-PEPC----ALPEKP----AVYTKVVHYRKWIKDTIA 258 + SWG + C + P + + W+K+ + Sbjct: 701 VISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >2KAI-A nrPDB Length = 80 Score = 128 bits (321), Expect = 4e-30, Method: Composition-based stats. Identities = 50/80 (62%), Positives = 61/80 (76%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 84 I+GG ECEK+S PWQVA+Y + CGGVLV+P+WVLTAAHC N +VWLGRHNLFE E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 DTGQRVPVSHSFPHPLYNMS 104 +T Q V+ FPHP +N+S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >3RU4-E nrPDB Length = 96 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 42/98 (42%), Positives = 53/98 (54%), Gaps = 7/98 (7%) Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN----GV 222 P LQ SL LLSN C + + K+ + M+CAG G +C GDSGGPLVC Sbjct: 2 TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWT 59 Query: 223 LQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 L GI SWG C+ P VY +V W++ T+AAN Sbjct: 60 LVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 96 >1BBR-E nrPDB Length = 109 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 37/100 (37%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG---GKDTCGGDSGGPLVC---- 219 +P LQ V+L L+ +C + ++T+ M CAG G D C GDSGGP V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 220 --NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 GI SWG E C K YT V +KWI+ I Sbjct: 66 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 104 >2HNT-F nrPDB Length = 105 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 37/100 (37%), Positives = 48/100 (48%), Gaps = 10/100 (10%) Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL-WTGGK--DTCGGDSGGPLVC---- 219 +P LQ V+L ++ +C + ++T+ M CAG GK D C GDSGGP V Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 220 --NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 GI SWG E C K YT V +KWI+ I Sbjct: 62 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 100 >2JET-C nrPDB Length = 99 Score = 116 bits (291), Expect = 9e-27, Method: Composition-based stats. Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 7/102 (6%) Query: 163 EEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCN-- 220 P LQ +L ++S C +++ K+T+ M CAG G D+C GDSGGPLVC Sbjct: 1 NALKTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKD 58 Query: 221 --GVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 L GI SWG C+ P VY++V W++ + AN Sbjct: 59 GVWTLAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILEAN 99 >1EPT-B nrPDB Length = 82 Score = 104 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 11/93 (11%) Query: 69 KNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE 128 QV LG HN+ E Q + + HP +N + L +D+ML++LS Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSS 49 Query: 129 PAKITDVVKVLGLPTQEPALGTTCYASGWGSIE 161 PA + V + LP A GT C SGWG+ + Sbjct: 50 PATLNSRVATVSLPRSCAAAGTECLISGWGNTK 82 >3F1S-B nrPDB Length = 283 Score = 89.1 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 54/239 (22%), Positives = 80/239 (33%), Gaps = 42/239 (17%) Query: 37 PWQVAV-YSHGWAHCGGVLVHPQWVLTAAHC--LKKNSQVWLGRHNLFEPEDTGQRVPVS 93 PWQV + S G CGGV++ +VLT A C L +N V + + ++ Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 121 Query: 94 HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA-----L 148 H H Y+ + +DL LL L P + + P ++ A Sbjct: 122 HVHVHMRYDA-----------DAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIP 170 Query: 149 GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGG--- 205 T SGW SL + L+ + C + + VT C Sbjct: 171 RTRGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHW 227 Query: 206 KDTCGGDSGGPLVCN-----GVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 D G +V L G+ G +P + TKV Y W K + A Sbjct: 228 MD-------GSVVTREHRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >3H5C-B nrPDB Length = 317 Score = 86.0 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 40/170 (23%), Positives = 61/170 (35%), Gaps = 25/170 (14%) Query: 37 PWQVAV-YSHGWAHCGGVLVHPQWVLTAAHC--LKKNSQVWLGRHNLFEPEDTGQRVPVS 93 PWQV + S G CGGV++ +VLT A C L +N V + + ++ Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 162 Query: 94 HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA-----L 148 H H Y+ + +DL LL L P + + P ++ A Sbjct: 163 HVHVHMRYDA-----------DAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIP 211 Query: 149 GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198 T SGW SL + L+ + C + + VT C Sbjct: 212 RTRGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYC 258 >2HNT-C nrPDB Length = 70 Score = 80.7 bits (198), Expect = 6e-16, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 12/70 (17%) Query: 25 IVGGWECEKHSQPWQVAVYSHGWA--HCGGVLVHPQWVLTAAHCL----------KKNSQ 72 IV G + E PWQV ++ CG L+ +WVLTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGRHNLFE 82 V +G+H+ Sbjct: 61 VRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 73.7 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 15/77 (19%) Query: 92 VSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA---- 147 + + HP YN E+ D+ L++L +P +D + + LP +E A Sbjct: 8 LEKIYIHPRYNWR----------ENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLL 57 Query: 148 -LGTTCYASGWGSIEPE 163 G +GWG+++ Sbjct: 58 QAGYKGRVTGWGNLKET 74 >1P3E-A nrPDB Length = 215 Score = 41.4 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 41/129 (31%), Gaps = 29/129 (22%) Query: 40 VAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHP 99 +A + G + C G L+ P +LT HC+ T R + +P Sbjct: 22 IAYITFGGSSCTGTLIAPNKILTNGHCVYN----------------TASRSYSAKGSVYP 65 Query: 100 LYNMSLLKHQSLRPDEDS-----------SHDLMLLRLSEPAKITDVVKVLGLPTQEPAL 148 N S + S E +D +++ I + V + Sbjct: 66 GMNDSTAVNGSANMTEFYVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNLT 123 Query: 149 GTTCYASGW 157 GTT SG+ Sbjct: 124 GTTIKISGY 132 >2EA3-A nrPDB Length = 189 Score = 35.2 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 211 GDSGGPLVCNGVLQGITSWGPEPCALPE 238 GDSGG L+ QG+TS G C Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2PFE-A nrPDB Length = 186 Score = 34.8 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 12/24 (50%), Positives = 14/24 (58%) Query: 211 GDSGGPLVCNGVLQGITSWGPEPC 234 GDSGGP + QG+TS G C Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDC 161 >2SFA-A nrPDB Length = 191 Score = 34.0 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 12/28 (42%) Query: 211 GDSGGPLVCNGVLQGITSWGPEPCALPE 238 GDSGG L G+TS G C Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >2OUA-A nrPDB Length = 188 Score = 33.7 bits (76), Expect = 0.094, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 13/28 (46%) Query: 211 GDSGGPLVCNGVLQGITSWGPEPCALPE 238 GDSGG + QG+TS G C Sbjct: 141 GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >1HPG-A nrPDB Length = 187 Score = 32.1 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 28/182 (15%), Positives = 52/182 (28%), Gaps = 43/182 (23%) Query: 56 HPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDE 115 ++ +TA HC ++ + G V V P + ++++ Sbjct: 24 GARYFVTAGHCTNISAN--------WSASSGGSVVGVREGTSFPTNDYGIVRYTDGSSPA 75 Query: 116 DSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVS 175 + DL + + +G SG + ++ V+ Sbjct: 76 GTV-DL----------YNGSTQDIS-SAANAVVGQAIKKSG-----STTKVTSGTVTAVN 118 Query: 176 LHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCG--GDSGGPLVCNGVLQGITSWGPEP 233 + + Y + M+ C GDSGG V GI S G Sbjct: 119 VTV--------NYGDGPVYNMV-------RTTACSAGGDSGGAHFAGSVALGIHS-GSSG 162 Query: 234 CA 235 C+ Sbjct: 163 CS 164 >2SGA-A nrPDB Length = 181 Score = 32.1 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 14/37 (37%), Gaps = 1/37 (2%) Query: 211 GDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVV 247 GDSGG L G+TS G C Y V Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGGT-TFYQPVT 170 >3LT3-A nrPDB Length = 217 Score = 31.7 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 201 LWTGGKDTCGGDSGGPLV-CNGVLQGITSWGP 231 ++T D GD+GGPL+ NG + G+ +G Sbjct: 151 VYTIRADVEQGDAGGPLIDLNGQVLGVV-FGA 181 >5ILB-A nrPDB Length = 474 Score = 30.6 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 22/48 (45%), Gaps = 4/48 (8%) Query: 29 WECEKHSQPWQVAVYSHGWAHCG-GVLVHPQWVLTAAHCLKKNSQVWL 75 +S PWQ + G ++ +LT AHC++ ++QV + Sbjct: 17 HTAPDYSLPWQ---KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV 61 >4FLN-A nrPDB Length = 539 Score = 30.6 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 22/48 (45%), Gaps = 4/48 (8%) Query: 29 WECEKHSQPWQVAVYSHGWAHCG-GVLVHPQWVLTAAHCLKKNSQVWL 75 +S PWQ + G ++ +LT AHC++ ++QV + Sbjct: 57 HTAPDYSLPWQ---KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV 101 >3W95-A nrPDB Length = 171 Score = 30.6 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 211 GDSGGPLVCNGVLQGITSWGPEP 233 GD+GG L C + GI S G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >4FVB-A nrPDB Length = 152 Score = 30.6 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 211 GDSGGPLVCNGVLQGITSWGPEP 233 GD+GG L C + GI S G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >5JYK-A nrPDB Length = 566 Score = 30.2 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 35 SQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL 75 S PWQ + G ++ + VLT AH ++ ++QV L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >5ILA-A nrPDB Length = 301 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 35 SQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL 75 S PWQ + G ++ + VLT AH ++ ++QV L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >2M5T-A nrPDB Length = 142 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 7/50 (14%) Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCG-GDSGGPLVCNGVLQGITSWGPEP 233 + Y + + +L G+ C GD+GG L+C + GI + G + Sbjct: 82 TQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >2HRV-A nrPDB Length = 142 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 22/50 (44%), Gaps = 7/50 (14%) Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCG-GDSGGPLVCNGVLQGITSWGPEP 233 + Y + + +L G+ C GD GG L+C + GI + G + Sbjct: 83 SEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAGGDN 126 >4B6E-A nrPDB Length = 683 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 210 GGDSGGPLVC-NGVLQGI 226 G SGGPL+C +G GI Sbjct: 171 KGSSGGPLLCPSGHAVGI 188 >6FE6-A nrPDB Length = 165 Score = 26.7 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 210 GGDSGGPLVC-NGVLQGI 226 G SGGPL+C +G GI Sbjct: 115 KGSSGGPLLCPSGHAVGI 132 >4U01-A nrPDB Length = 203 Score = 26.7 bits (58), Expect = 9.9, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 210 GGDSGGPLVC-NGVLQGI 226 G SGGPL+C +G GI Sbjct: 137 KGSSGGPLLCPSGHAVGI 154 >4K8B-A nrPDB Length = 181 Score = 26.7 bits (58), Expect = 9.9, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 210 GGDSGGPLVC-NGVLQGI 226 G SGGPL+C +G GI Sbjct: 136 KGSSGGPLLCPSGHAVGI 153 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.157 0.582 Lambda K H 0.267 0.0483 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,528,016 Number of Sequences: 36641 Number of extensions: 578073 Number of successful extensions: 2685 Number of sequences better than 10.0: 185 Number of HSP's better than 10.0 without gapping: 331 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1121 Number of HSP's gapped (non-prelim): 373 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.1 bits)