BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20132 (328 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4H27-A nrPDB 663 0.0 1PWH-A nrPDB 526 e-150 2RKB-A nrPDB 334 3e-92 5C3U-A nrPDB 213 7e-56 3IAU-A nrPDB 114 7e-26 1TDJ-A nrPDB 100 1e-21 5X2L-A nrPDB 91 6e-19 5YBW-A nrPDB 80 2e-15 5CVC-A nrPDB 79 3e-15 3L6C-A nrPDB 73 1e-13 1V71-A nrPDB 73 2e-13 6NMX-A nrPDB 72 4e-13 2D1F-A nrPDB 72 4e-13 1UIN-A nrPDB 67 7e-12 2GN1-A nrPDB 64 1e-10 2ZSJ-A nrPDB 62 4e-10 1VE5-A nrPDB 62 4e-10 5JJC-A nrPDB 61 6e-10 5YGR-A nrPDB 49 2e-06 5D84-A nrPDB 48 7e-06 1J0B-A nrPDB 43 2e-04 5XW3-A nrPDB 40 0.001 5I7O-A nrPDB 40 0.002 5J5V-A nrPDB 38 0.005 3FCA-A nrPDB 38 0.006 5B55-A nrPDB 38 0.006 6AHI-A nrPDB 37 0.009 2PQM-A nrPDB 37 0.009 3X43-A nrPDB 35 0.056 5XA2-A nrPDB 35 0.062 4LMA-A nrPDB 34 0.084 3JBH-C nrPDB 34 0.095 2BHS-A nrPDB 33 0.13 5XCN-X nrPDB 33 0.17 6HUL-B nrPDB 33 0.23 3PC3-A nrPDB 32 0.37 4LMB-A nrPDB 32 0.49 6EQN-B nrPDB 31 0.80 3VBE-A nrPDB 30 1.2 4I1Y-A nrPDB 30 1.2 5XEM-A nrPDB 30 1.3 1OZV-A nrPDB 30 1.3 2JC3-A nrPDB 30 1.6 3SS9-X nrPDB 30 1.9 3R0X-A nrPDB 29 2.2 1X1Q-A nrPDB 29 2.5 2EGU-A nrPDB 29 3.2 1E5X-A nrPDB 28 3.7 4C2K-A nrPDB 28 4.0 2OB5-A nrPDB 28 4.7 3T4P-A nrPDB 28 5.2 5H2U-A nrPDB 28 5.7 1F8S-A nrPDB 28 5.8 1N5D-A nrPDB 28 6.2 5OHX-A nrPDB 27 8.9 >4H27-A nrPDB Length = 364 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/328 (99%), Positives = 327/328 (99%) Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF Sbjct: 37 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 96 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120 VCSS+GNAGMAAAYAARQLGVPATIVVP TTPALTIERLKNEGATVKVVGELLDEAFELA Sbjct: 97 VCSSSGNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVVGELLDEAFELA 156 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL Sbjct: 157 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 216 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP Sbjct: 217 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 276 Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV Sbjct: 277 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 336 Query: 301 IVCGGSNISLAQLRALKEQLGMTNRLPK 328 IVCGGSNISLAQLRALKEQLGMTNRLPK Sbjct: 337 IVCGGSNISLAQLRALKEQLGMTNRLPK 364 >1PWH-A nrPDB Length = 327 Score = 526 bits (1354), Expect = e-150, Method: Compositional matrix adjust. Identities = 274/326 (84%), Positives = 293/326 (89%) Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60 M + E LHVKTP+RDSMALSK+AGTSV+LKMDS+QPSGSFKIRGIGH CK AKQGC HF Sbjct: 1 MAAQESLHVKTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRGIGHLCKMKAKQGCKHF 60 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120 VCSSAGNAGMA AYAAR+LG+PATIVVPSTTPALTIERLKNEGATV+VVGE+LDEA +LA Sbjct: 61 VCSSAGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVVGEMLDEAIQLA 120 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 KAL KNNPGWVYI PFDDPLIWEGH S+VKELKETL KPGAI LSVGGGGLLCGVVQGL Sbjct: 121 KALEKNNPGWVYISPFDDPLIWEGHTSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQGL 180 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240 +EVGW DVP+IAMETFGAHSFHAA GKLV+LPKITSVAKALGV TVGAQ LKLF EHP Sbjct: 181 REVGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKITSVAKALGVNTVGAQTLKLFYEHP 240 Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 IFSEVISDQEAV AIEKFVDDEKILVEPACGAALAAVYS V+ +LQ E L+TPL SLVV Sbjct: 241 IFSEVISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEARLQTPLASLVV 300 Query: 301 IVCGGSNISLAQLRALKEQLGMTNRL 326 IVCGGSNISLAQL+ALK QLG+ L Sbjct: 301 IVCGGSNISLAQLQALKAQLGLNELL 326 >2RKB-A nrPDB Length = 318 Score = 334 bits (856), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 196/317 (61%), Positives = 249/317 (78%), Gaps = 1/317 (0%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS 64 EP HV TP+ +S ALS++AG V+LK ++ QPSGSFKIRGIGHFC+ AK+GC H VCSS Sbjct: 2 EPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSS 61 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 GNAG+AAAYAAR+LG+PATIV+P +T ++RL+ EGA V++ G++ DEA A+ LA Sbjct: 62 GGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELA 121 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 K + GW +PPFD PLIW+GHAS+V+ELK L PGA+ L+VGGGGLL GVV GL EVG Sbjct: 122 KRD-GWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVG 180 Query: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 244 W VP+IAMET GAH F+AA TAGKLV+LP ITSVAK+LG KTV A+AL+ Q I SE Sbjct: 181 WQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSE 240 Query: 245 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304 V+ D EAV+A+++ +DDE++LVEPACGAALAA+YS ++++LQ EG L L S+VVIVCG Sbjct: 241 VVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCG 300 Query: 305 GSNISLAQLRALKEQLG 321 G+NI+ +L+ALK LG Sbjct: 301 GNNINSRELQALKTHLG 317 >5C3U-A nrPDB Length = 366 Score = 213 bits (543), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 133/318 (41%), Positives = 195/318 (61%), Gaps = 8/318 (2%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKR--WAKQGCAHFVC 62 + LHV TP+ + L+K +V+LKM++ QPSGS K+RGIG FC + + FVC Sbjct: 16 QSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQTRGTNIQFVC 75 Query: 63 SSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKA 122 S N +A +Y ARQLGV A IVVP T + ++ +G+ + + GE A A+ Sbjct: 76 GSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLILYGENWTAAEVHARK 135 Query: 123 LAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKP-GAIALSVGGGGLLCGVVQGLQ 181 L + N +Y+P D LIW+GH++IV+ELK L + P AI VGGGGLL GV+ GLQ Sbjct: 136 LVRRN--GIYVPSSDHALIWQGHSTIVQELKTQLNDNPPAAIICPVGGGGLLNGVIMGLQ 193 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 E W DVPVIA+ET G+++F A+ AG+LV + K ++A +L K V +++L+L HP+ Sbjct: 194 EADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLISKAVSSKSLELSLNHPV 253 Query: 242 FSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 +SD A A+ F +D K+LVE + GAAL+ Y+H+I+ + +P +VV+ Sbjct: 254 VPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRDILPS---LSPAKDVVVL 310 Query: 302 VCGGSNISLAQLRALKEQ 319 V GGS+ISLA L +++ Sbjct: 311 VTGGSDISLAHLDEYRKK 328 >3IAU-A nrPDB Length = 366 Score = 114 bits (284), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 86/316 (27%), Positives = 156/316 (49%), Gaps = 14/316 (4%) Query: 9 VKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH-FVCSSAGN 67 +++P+ + LS G + Y+K + Q SFK+RG + +++ + +SAGN Sbjct: 59 IESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELDKGVITASAGN 118 Query: 68 AGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNN 127 A A ++L A IV+P+TTP + I+ ++ G V + G+ DEA A L++ + Sbjct: 119 HAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTHALELSEKD 178 Query: 128 PGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD 187 G YIPPFDDP + +G +I E+ L + A+ + VGGGGL+ GV +++ + Sbjct: 179 -GLKYIPPFDDPGVIKGQGTIGTEINRQLKDIH-AVFIPVGGGGLIAGVATFFKQIAP-N 235 Query: 188 VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS 247 +I +E +GA S + G V L + + A + V VG QE +++ Sbjct: 236 TKIIGVEPYGAASMTLSLHEGHRVKLSNVDTFADGVAVALVGEYTFAKCQELIDGMVLVA 295 Query: 248 DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHV-IQKLQLEGNLRTPLPSLVVIVCGGS 306 + AAI+ D+ + ++E + A+A ++ K++ E +V + G+ Sbjct: 296 NDGISAAIKDVYDEGRNILETSGAVAIAGAAAYCEFYKIKNEN---------IVAIASGA 346 Query: 307 NISLAQLRALKEQLGM 322 N+ ++L + E G+ Sbjct: 347 NMDFSKLHKVTELAGL 362 >1TDJ-A nrPDB Length = 514 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/314 (26%), Positives = 154/314 (49%), Gaps = 20/314 (6%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH-FVCSSAGNAG 69 TP++ LS + +K + QP SFK+RG ++ AH + +SAGN Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHA 91 Query: 70 MAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNPG 129 A+++ +LGV A IV+P+ T + ++ ++ G V + G DEA A L++ G Sbjct: 92 QGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQ-G 150 Query: 130 WVYIPPFDDPLIWEGHASIVKEL--KETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD 187 + ++PPFD P++ G ++ EL ++ ++ G + +++ L Sbjct: 151 FTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMP----Q 206 Query: 188 VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS 247 + VIA+E + AA AG V LP++ A+ + VK +G + +L QE+ ++I+ Sbjct: 207 IKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEY--LDDIIT 264 Query: 248 -DQEAV-AAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGG 305 D +A+ AA++ +D + + EP+ ALA + ++ N+R + + G Sbjct: 265 VDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALH-----NIRG---ERLAHILSG 316 Query: 306 SNISLAQLRALKEQ 319 +N++ LR + E+ Sbjct: 317 ANVNFHGLRYVSER 330 >5X2L-A nrPDB Length = 348 Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 91/311 (29%), Positives = 149/311 (47%), Gaps = 28/311 (9%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66 TP+ S L+++ G +++ K + Q +GSFKIRG + + V S+G Sbjct: 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSG 85 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-LAKALAK 125 N G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E +AK + + Sbjct: 86 NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-VYCEPSDESRENVAKRVTE 144 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKP--GAIALSVGGGGLLCGVVQGLQEV 183 G + + P +P + G +I E+ L + P A+ + VGGGG+L G+ ++ + Sbjct: 145 ETEG-IMVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVPVGGGGMLAGIAITVKAL 200 Query: 184 GWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAK-ALGVK-TVGAQALKLFQE--H 239 V V A E A + + GKL +P + A GVK ++G + ++ Sbjct: 201 K-PSVKVYAAEPSNADDCYQSKLKGKL--MPNLYPPETIADGVKSSIGLNTWPIIRDLVD 257 Query: 240 PIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLV 299 IF+ +++ E A + + K+L+EP G +AAV S Q + +P + Sbjct: 258 DIFT--VTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTV-------SPEVKNI 308 Query: 300 VIVCGGSNISL 310 IV G N+ L Sbjct: 309 CIVLSGGNVDL 319 >5YBW-A nrPDB Length = 329 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 86/310 (27%), Positives = 141/310 (45%), Gaps = 20/310 (6%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH--FCKRWAKQGCAHFVCSSAGNA 68 +P D M SK AG Y K ++ Q +GSFK RG + C + A V S+GN Sbjct: 30 SPTFDRMVGSK-AGRQFYFKAENLQKTGSFKARGALNAILCALEREPSLAGVVTHSSGNH 88 Query: 69 GMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNP 128 G A A+A+++ GV +VVP T P + + ++N GA V E + LAK+ Sbjct: 89 GQALAWASKRAGVKCCVVVPKTAPQVKFDAMENYGAEVVKCEPNPTSRKETCEGLAKSR- 147 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWEKP--GAIALSVGGGGLLCGVVQGLQEVGWG 186 G+ YI DD + G +I EL L ++P AI +SV GG+ G+ + Sbjct: 148 GYKYISSSDDYDVIAGQGTIALEL---LQQQPDLDAILVSVSAGGMASGICVYTKNTK-S 203 Query: 187 DVPVIAMETFGAHSFHAATTAGKLVSLPK--ITSVAKALGVKTVGAQALKLFQEHPIFSE 244 D+ V +E G + +L P + ++A + ++ G + + E P Sbjct: 204 DLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIADGIILQQCGNKTWPIILELPEKEV 263 Query: 245 VISDQEAVAAIEKFVDDE-KILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVC 303 + + + + +FV K+++E A GA +AA + Q E + +I+C Sbjct: 264 ITVNNDNIVEAMRFVFARMKLVIEAAAGATVAAAMTERFQNFHPEAK------KVGIILC 317 Query: 304 GGSNISLAQL 313 GG N+ + +L Sbjct: 318 GG-NVDIEKL 326 >5CVC-A nrPDB Length = 346 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/219 (28%), Positives = 103/219 (47%), Gaps = 4/219 (1%) Query: 6 PLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH-FCKRWAKQGCAHFVCSS 64 P +TP+ S ++ M G ++ K + Q +G+FKIRG + +Q V S Sbjct: 32 PYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSIFALDDEQVSKGVVTHS 91 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 +GN A A AA+ G+PA IV+P PA +E +K G + + + E+ E Sbjct: 92 SGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGHI-IWSDASIESREYVSKRV 150 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 + G V I P + G ++ EL E + E I + + GGGL+ GV + + Sbjct: 151 QEETGAVLIHPINSKYTISGQGTVSLELLEQVPEID-TIIVPISGGGLISGVALAAKAIN 209 Query: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKAL 223 + ++A E GA + AGK+++LP ++A L Sbjct: 210 -PSIRILAAEPKGADDSAQSKAAGKIITLPSTNTIADGL 247 >3L6C-A nrPDB Length = 339 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 89/322 (27%), Positives = 148/322 (45%), Gaps = 34/322 (10%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG----IGHFCKRWAKQGCAHFVCSSAG 66 TP+ S L+++AG +++ K + Q +GSFKIRG I + V S+G Sbjct: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSG 85 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-LAKALAK 125 N G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E +A+ + + Sbjct: 86 NHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASI-VYSEPSDESRENVAQRIIQ 144 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIAL-----SVGGGGLLCGVVQGL 180 G + + P +P + G +I E+ L + P AL G + ++ L Sbjct: 145 ETEG-ILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVPVGGGGMVAGIAITIKTL 200 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLV-SLPKITSVAKALGVK-TVGAQALKLFQE 238 + V V A E A + + G+L +L ++A GVK ++G + ++ Sbjct: 201 KP----SVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIAD--GVKSSIGLNTWPIIRD 254 Query: 239 --HPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLP 296 +F+ +++ E A + + K+L+EP G LAAV S Q + +P Sbjct: 255 LVDDVFT--VTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTV-------SPEV 305 Query: 297 SLVVIVCGGSNISLAQLRALKE 318 + IV G N+ L L +K+ Sbjct: 306 KNICIVLSGGNVDLTSLSWVKQ 327 >1V71-A nrPDB Length = 323 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 69/270 (25%), Positives = 120/270 (44%), Gaps = 8/270 (2%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG-IGHFCKRWAKQGCAHFVCSSAGNA 68 KTP+ S ++K V+ K ++ Q G+FK RG + + Q A + S+GN Sbjct: 26 KTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQRKAGVLTFSSGNH 85 Query: 69 GMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNP 128 A A +A+ LG+PA I++P P + K G V + D+ ++AK +++ Sbjct: 86 AQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISERE- 144 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAI-ALSVGGGGLLCGVVQGLQEVGWG- 186 G IPP+D P + G + KE L+E+ G + AL V GG L + Sbjct: 145 GLTIIPPYDHPHVLAGQGTAAKE----LFEEVGPLDALFVCLGGGGLLSGSALAARHFAP 200 Query: 187 DVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVI 246 + V +E + + G +V + ++A + +G + +E + Sbjct: 201 NCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDILTV 260 Query: 247 SDQEAVAAIEKFVDDEKILVEPACGAALAA 276 SD+E + ++ + KI+VEP + AA Sbjct: 261 SDEELIDCLKFYAARMKIVVEPTGCLSFAA 290 >6NMX-A nrPDB Length = 354 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 64/274 (23%), Positives = 125/274 (45%), Gaps = 5/274 (1%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAG 69 TP+ LS+ G +++K + P+GSFK RG+ + ++G +C+S GN Sbjct: 30 NTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEGNDTIMCASTGNTS 89 Query: 70 MAAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKALAKNNP 128 AAA A + + +++P+ A + + GA + + D+A ++ +++ + +P Sbjct: 90 AAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDGNFDDALKIVRSICEKSP 149 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD- 187 + + +P EG + E+ E L E P +A+ VG G + +G +E + Sbjct: 150 --IALVNSVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYWKGFKEYHEKNG 207 Query: 188 VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS 247 + M F A AA +++ P+ + A +G +A+K +E + ++ Sbjct: 208 TSLPKMRGFEAEG-SAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAEESNGKIDEVT 266 Query: 248 DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHV 281 D E + A + +E + EP A++A V V Sbjct: 267 DDEILHAYQLIAREEGVFAEPGSCASIAGVLKQV 300 >2D1F-A nrPDB Length = 360 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 70/269 (26%), Positives = 119/269 (44%), Gaps = 3/269 (1%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGM 70 TP+ + LSK G +++LK++ P+GSFK RG+ G +C+S GN Sbjct: 39 TPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSA 98 Query: 71 AAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKALAKNNPG 129 +AA A + G+ +++P A+ + + GA + + D+ ELA+ +A + P Sbjct: 99 SAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPT 158 Query: 130 WVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVP 189 + +P+ EG + E+ + L P AL VG G + +G E + Sbjct: 159 ISLVNSV-NPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLI 217 Query: 190 VIAMETFGAHSFHAATTA-GKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISD 248 G + AA G+ VS P+ + A +G A++ Q+ SD Sbjct: 218 DKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASD 277 Query: 249 QEAVAAIEKFVDDEKILVEPACGAALAAV 277 +E +AA E + VEPA A++A + Sbjct: 278 EEILAAYHLVARVEGVFVEPASAASIAGL 306 >1UIN-A nrPDB Length = 351 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 80/298 (26%), Positives = 128/298 (42%), Gaps = 32/298 (10%) Query: 20 SKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQL 79 ++ G +Y K + P+GSFK RG+ + + G C+S GN +AA A + Sbjct: 40 ARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGGAQAVACASTGNTAASAAAYAARA 99 Query: 80 GVPATIVVPSTTPAL--TIERLKNEGATVKVVGELLDEAFELAKALAKNNPGWVYIPPFD 137 G+ A +V+P+ AL + L + V+V G D+A L + L + P V + Sbjct: 100 GILAIVVLPAGYVALGKVAQSLVHGARIVQVEGN-FDDALRLTQKLTEAFP--VALVNSV 156 Query: 138 DPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFG 197 +P EG ++ E+ + L + P AL VG G + G + A G Sbjct: 157 NPHRLEGQKTLAFEVVDELGDAPHYHALPVGNAGNITAHWMGYK----------AYHALG 206 Query: 198 AHS-------FHAATTA----GKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVI 246 F AA A G+ V P+ + A +G A++ +E E + Sbjct: 207 KAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAIRIGNPASWQGAVRAKEESGGVIEAV 266 Query: 247 SDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304 +D+E + A +E I EPA AA+A V+ KL EG L P ++V+ + G Sbjct: 267 TDEEILFAYRYLAREEGIFCEPASAAAMAGVF-----KLLREGRLE-PESTVVLTLTG 318 >2GN1-A nrPDB Length = 342 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 8/158 (5%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG----IGHFCKRWAKQGCAHFVCSSA 65 KT + S S+ ++LK ++ Q +GSFKIRG + + ++G V SA Sbjct: 40 KTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKG---VVACSA 96 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 125 GN + + LG+ +V+P P + + A V + G+ ++ + + Sbjct: 97 GNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVE 156 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAI 163 G ++IPP+DDP + G +I E+ E L++ I Sbjct: 157 TE-GRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVI 193 >2ZSJ-A nrPDB Length = 352 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 71/275 (25%), Positives = 124/275 (45%), Gaps = 12/275 (4%) Query: 10 KTPIRDSMALSKMAGTS--VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGN 67 TP+ ++ L++ G +YLK + P+GSFK RG+ + + G +C+S GN Sbjct: 30 NTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKAVEAGKRAVICASTGN 89 Query: 68 AGMAAAYAARQLGVPATIVVPSTTPALTIERLKNE---GATVKVVGELLDEAFELAKALA 124 +AA A + G+ A +++P A+ I +L GA V + D+A + + + Sbjct: 90 TSASAAAYAARAGLRAYVLLPKG--AVAIGKLSQAMIYGAKVLAIQGTFDDALNIVRKIG 147 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 +N P V I +P EG + E+ +TL E P + VG G + +G + + Sbjct: 148 ENFP--VEIVNSVNPYRIEGQKTAAFEICDTLGEAPDYHFIPVGNAGNITAYWKGFK-IY 204 Query: 185 WGDVPVIAM-ETFGAHSFHAA-TTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 + + + + G + AA G + P+ + A +G ALK QE Sbjct: 205 YEEGKITKLPRMMGWQAEGAAPIVKGYPIKNPQTIATAIKIGNPYSWKSALKAAQESGGK 264 Query: 243 SEVISDQEAVAAIEKFVDDEKILVEPACGAALAAV 277 + +SD E + A + E + EPA A++A + Sbjct: 265 IDAVSDSEILYAYKLIASTEGVFCEPASAASVAGL 299 >1VE5-A nrPDB Length = 311 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 10/280 (3%) Query: 6 PLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSA 65 P +TP+ S L + G + LK + Q +GSFK RG K A + + S+ Sbjct: 16 PYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGA--LSKALALENPKGLLAVSS 73 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 125 GN AYAA+ LGV A +V+P + GA V G E+A+AL + Sbjct: 74 GNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVDRGVTAKNREEVARALQE 133 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEK---PGAIALSVGGGGLLCGVVQGLQE 182 G+ I PFDDPL+ G + EL PGA+ VGGGGLL G+ ++ Sbjct: 134 ET-GYALIHPFDDPLVIAGQGTAGLELLAQAGRMGVFPGAVLAPVGGGGLLAGLATAVKA 192 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKT--VGAQALKLFQEHP 240 + + V+ +E A + AG+++ L + +A GV+T +G + + +E Sbjct: 193 LSPTTL-VLGVEPEAADDAKRSLEAGRILRL-EAPPRTRADGVRTLSLGERTFPILRERV 250 Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSH 280 +S++ + A K +VEP LAAV H Sbjct: 251 DGILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVLEH 290 >5JJC-A nrPDB Length = 342 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 78/318 (24%), Positives = 138/318 (43%), Gaps = 29/318 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSA 65 TP+ S++ G +Y K + P S K R + + K+G V +A Sbjct: 11 NTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRPGGVIVEGTA 70 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--------GELLDEAF 117 GN G+ A+ LG IV+P T + L+ GA + V + + Sbjct: 71 GNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRNPNNAVRLSG 130 Query: 118 ELAKALAKNNP-GWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCG 175 LA+ LAK P G ++ FD+ + + H + +E+ ++ +VG GG L G Sbjct: 131 RLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAAVGSGGTLAG 190 Query: 176 VVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKL 235 GL+E ++ + + GA + HA T G+L + + S+ + +G + A L+ Sbjct: 191 TAIGLKERNH-NIKIALADPHGA-ALHAFYTTGELKA--EGDSITEGIGQGRITAN-LEG 245 Query: 236 FQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPL 295 F P FS I D EA+ + V++E + + + G +A ++L +L P Sbjct: 246 FT--PDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGA-------IRLAKDL-GPG 295 Query: 296 PSLVVIVCGGSNISLAQL 313 ++V ++C N ++L Sbjct: 296 HTIVTVLCDYGNRYQSKL 313 >5YGR-A nrPDB Length = 404 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 13/157 (8%) Query: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFEL 119 FV ++ GN G A+AA QLG+ A + +P + + E +++ GA + D+A L Sbjct: 120 FVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDDAVRL 179 Query: 120 AKALAKNNPGWVYIPP-----FDDPLIW--EGHASIVKELKETLWEK----PGAIALSVG 168 A +A+ GWV + +++ W +G+ ++ E E L E P + L G Sbjct: 180 AHRMAQTK-GWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAG 238 Query: 169 GGGLLCGVVQGLQEVGWGDVP-VIAMETFGAHSFHAA 204 G V+ E ++P +I +E A+ + + Sbjct: 239 VGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQS 275 >5D84-A nrPDB Length = 326 Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 62/285 (21%), Positives = 119/285 (41%), Gaps = 32/285 (11%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAGNAGMAAAYAARQLGVP 82 V+ K++ P GS K R + + K G H + S++GN G+A A A+ G+ Sbjct: 33 VFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLK 92 Query: 83 ATIVVPSTTPALTIERLKNEGATVKVV-------GELLDEAFELAKALAKNNPGWVYIPP 135 T VV ++ +K+ GA V++V G L+ ++ + LA + + +I Sbjct: 93 LTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAY-WINQ 151 Query: 136 FDDPLIWEGHASIV-KELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAME 194 + + L W+ H E+ ET+ + V G + G+ + ++EV + ++A++ Sbjct: 152 YANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEV-HPNAQIVAVD 210 Query: 195 TFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVI--SDQEAV 252 G+ F +L +GA + ++VI D ++ Sbjct: 211 AKGSVIFGDKPINRELPG---------------IGASRVPEILNRSEINQVIHVDDYQSA 255 Query: 253 AAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 K +D E I + G+ +AA+ +I ++ + T LP Sbjct: 256 LGCRKLIDYEGIFAGGSTGSIIAAI-EQLITSIEEGATIVTILPD 299 >1J0B-A nrPDB Length = 325 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 96/235 (40%), Gaps = 32/235 (13%) Query: 10 KTPIRDSMALSKMAGTSVYLKMD--SAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSA-- 65 +TPI+ +S+ G VY+K D + G KIR + + +G + A Sbjct: 21 ETPIQYLPNISREIGADVYIKRDDLTGLGIGGNKIRKLEYLLGDALSKGADVVITVGAVH 80 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVG------------ELL 113 N AA++LG+ A +V+ E LK K++G EL+ Sbjct: 81 SNHAFVTGLAAKKLGLDAILVLRGK------EELKGNYLLDKIMGIETRVYDAKDSFELM 134 Query: 114 DEAFELAKALAKNNPGWVYIPPFD-DPLIWEGHASIVKELKETLWEKPGAIALSVGGGGL 172 A E+A+ L + IPP P+ G+ V E+ K +I ++ G GG Sbjct: 135 KYAEEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVGEIATQSEVKFDSIVVAAGSGGT 194 Query: 173 LCGVVQGLQEVGWGDVPV-IAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVK 226 L G+ GL + PV IA+ FG KL +L I A+ LGVK Sbjct: 195 LAGLSLGLSILNEDIRPVGIAVGRFG------EVMTSKLDNL--IKEAAELLGVK 241 >5XW3-A nrPDB Length = 315 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 70/279 (25%), Positives = 109/279 (39%), Gaps = 33/279 (11%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAG 66 TPI + S G ++ K++ P GS K R + ++G + +AG Sbjct: 14 TPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGLVTEGGTIIEPTAG 73 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKN 126 N G+ A AA Q + + VP E +K GAT VV ++ + A+AK Sbjct: 74 NTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGAT--VVHTPTEQG--MTGAIAKA 129 Query: 127 NPGWVYIPPFDDPLIWEGHAS---IVKELKETLWEK-PGAIALSVGG---GGLLCGVVQG 179 IP P + A+ K L LW G I + V G GG G Sbjct: 130 KELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTGGTFMGTASY 189 Query: 180 LQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEH 239 L+E D+ + +E G + GK A + + +G + + F + Sbjct: 190 LKEKNI-DIKTVIVEPEG-----SILNGGK----------AGSHETEGIGLEFIPPFLKT 233 Query: 240 PIFSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAA 276 F E+ ISD+ A +++ E +LV + GAA A Sbjct: 234 SYFDEIHTISDRNAFLRVKELAQKEGLLVGSSSGAAFHA 272 >5I7O-A nrPDB Length = 326 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 6/125 (4%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAGNAGMAAAYAARQLGVP 82 ++ K++ P+GS K R ++ G A + ++GN G++ A AAR G Sbjct: 40 LWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYR 99 Query: 83 ATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKALAKNNPGWVYIPPFDDPL 140 V+P T + L+ GA + + A AK LA NP WV + + +P Sbjct: 100 LICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPA 159 Query: 141 IWEGH 145 + H Sbjct: 160 NTDSH 164 >5J5V-A nrPDB Length = 323 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 16/150 (10%) Query: 19 LSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAGNAGMAAAY 74 L+++ + K++S PS S K R + K+G V ++GN G+A AY Sbjct: 20 LNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAY 79 Query: 75 AARQLGVPATIVVPSTTPALTIER---LKNEGATVKVV--GELLDEAFELAKALAKNNP- 128 A G T+ +P T ++IER LK GA + + + + A + A+ + +NP Sbjct: 80 VAAARGYKLTLTMPET---MSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASNPE 136 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWE 158 ++ + F +P E H K +WE Sbjct: 137 KYLLLQQFSNPANPEIHE---KTTGPEIWE 163 >3FCA-A nrPDB Length = 291 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 69/290 (23%), Positives = 119/290 (41%), Gaps = 43/290 (14%) Query: 25 TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH--FVCSSAGNAGMAAAYAARQLGVP 82 + + LK++ P GS K R K+G V ++GN G+A A + G Sbjct: 19 SRIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNGIVEPTSGNMGIAIAMIGAKRGHR 78 Query: 83 ATIVVPSTTPALTIER---LKNEGATVKVV-GEL-LDEAFELAKALAKNNPGWVYIPPFD 137 + +P T +++ER LK GA + + GEL + A E A +++ G + F+ Sbjct: 79 VILTMPET---MSVERRKVLKMLGAELVLTPGELGMKGAVEKALEISRET-GAHMLNQFE 134 Query: 138 DPL-IWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAME-- 194 +P ++ + E+ + + + A VG GG + GV + L+ V ++A+E Sbjct: 135 NPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGVGRVLKGFFGNGVKIVAVEPA 194 Query: 195 -----TFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS-- 247 + G HA ++ +GA + + + EVI+ Sbjct: 195 KSPVLSGGQPGKHA---------------------IQGIGAGFVPKILDRSVIDEVITVE 233 Query: 248 DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 D+EA E +LV + GA +AA V QKL + + T P Sbjct: 234 DEEAYEMARYLAKKEGLLVGISSGANVAAALK-VAQKLGPDARVVTVAPD 282 >5B55-A nrPDB Length = 340 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 18/175 (10%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH-----FCKRWAKQGCAH 59 E L KTP+ + + K +++K +S +GS K R + + K K+G A Sbjct: 14 ENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKG-AP 72 Query: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV----GELLDE 115 V +++GN G+A + LG P I +P +++ GA + +V G L Sbjct: 73 IVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLG- 131 Query: 116 AFELAKALAKNNPGWVYIPP-FDDPLIWEGHA-----SIVKELKETLWEKPGAIA 164 + E K AKNNP Y+P F + E H IV E+K G +A Sbjct: 132 SIEKTKEFAKNNPD-TYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVA 185 >6AHI-A nrPDB Length = 314 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 61/265 (23%), Positives = 105/265 (39%), Gaps = 33/265 (12%) Query: 25 TSVYLKMDSAQPSGSFKIR----GIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQLG 80 +++Y K++ P GS K R IG K + +AGN G+A A A + Sbjct: 30 SAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGKITSKTTIIEPTAGNTGIALALVAIKHH 89 Query: 81 VPATIVVPSTTPALTIERLKNEGATV--KVVGELLDEAFELAKALAKNNPGWVYIP---- 134 + VVP + ++ GA V E + A + +K LA++ P Y+P Sbjct: 90 LKTIFVVPEKFSTEKQQIMRALGALVINTPTSEGISGAIKKSKELAESIPDS-YLPLQFE 148 Query: 135 -PFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAM 193 P D+P + + ++ E+ + L + +G GG G + L+E +P I + Sbjct: 149 NP-DNPAAY--YHTLAPEIVQELGTNLTSFVAGIGSGGTFAGTARYLKE----RIPAIRL 201 Query: 194 ETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFS--EVISDQEA 251 G + G+ ++ +G + + F E+ E ISD+E Sbjct: 202 --IGVEPEGSILNGGE----------PGPHEIEGIGVEFIPPFFENLDIDGFETISDEEG 249 Query: 252 VAAIEKFVDDEKILVEPACGAALAA 276 + K +LV + GAA A Sbjct: 250 FSYTRKLAKKNGLLVGSSSGAAFVA 274 >2PQM-A nrPDB Length = 343 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 23/168 (13%) Query: 24 GTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQG----CAHFVCSSAGNAGMAAAYAARQL 79 GT + +K++ P S K R + + K G + S++GN G+A A Sbjct: 41 GTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVF 100 Query: 80 GVPATIVVPSTTPALTIER---LKNEGATVKVVGELLDE-------AFELAKALAKNNPG 129 G I +PST +++ER +K GA + +L E A E + K NPG Sbjct: 101 GYRVNIAMPST---MSVERQMIMKAFGAEL-----ILTEGKKGMPGAIEEVNKMIKENPG 152 Query: 130 WVYIP-PFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGV 176 ++ F +P H E+ E + + +VG G + GV Sbjct: 153 KYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGV 200 >3X43-A nrPDB Length = 332 Score = 34.7 bits (78), Expect = 0.056, Method: Compositional matrix adjust. Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 18/141 (12%) Query: 10 KTPIRDSMALSKMA--GTSVYLKMDSAQPSGSFKIR-----GIGHFCKRWAKQGCAHFVC 62 +TPI + L +MA TSVY+K++S P GS K R + K K G C Sbjct: 13 RTPI---VRLQRMAPEHTSVYVKVESFNPGGSVKDRLALSVVLDAEAKGLLKPGDTIVEC 69 Query: 63 SSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLK----NEGATVKVVGELLDEAFE 118 +S GN G+A A A G V+ T ++ER K G V G L + Sbjct: 70 TS-GNVGIALAMVAAARGYRFVAVMGDT---YSVERRKLIRAYGGKLVLFPGHLGSKGGN 125 Query: 119 LAKALAKNNPGWVYIPPFDDP 139 L GW FD+P Sbjct: 126 LIADELAEKYGWFRARQFDNP 146 >5XA2-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.062, Method: Compositional matrix adjust. Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 15/140 (10%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCA-----HFVCSS 64 +TP+ L+ + V K++ P+ S K R IG A+Q H V + Sbjct: 13 RTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCR-IGAAMIWDAEQSGKLKPGMHVVEPT 71 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIER---LKNEGATVKVV--GELLDEAFEL 119 +GN G+A A+ G T+ +P T ++IER LK+ GA + + + + A Sbjct: 72 SGNTGIALAFVCAARGYKLTLTMPET---MSIERRMMLKSFGADLVLTPGADGMKGAISK 128 Query: 120 AKALAKNNPGWVYIPPFDDP 139 A+ LA PGW F +P Sbjct: 129 AEELAA-QPGWFIPQQFKNP 147 >4LMA-A nrPDB Length = 326 Score = 34.3 bits (77), Expect = 0.084, Method: Compositional matrix adjust. Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 13/129 (10%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH-----FVCSSAGNAGMAAAYAARQLGV 81 + +K++ P+ S K R H K G + V ++GN G+A A A G Sbjct: 39 IVMKLEGMNPAASVKDRIGTHMINSAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGY 98 Query: 82 PATIVVPSTTPALTIER---LKNEGATVKVV--GELLDEAFELAKALAKNNPGWVYIPPF 136 + +P T +++ER LK GAT+++ + + A A+ + + PG + F Sbjct: 99 RLILTMPET---MSLERRAMLKAYGATLELTPGSQGMKGAILRAQQIVDSIPGAYMLQQF 155 Query: 137 DDPLIWEGH 145 +P E H Sbjct: 156 RNPSNPEIH 164 >3JBH-C nrPDB Length = 156 Score = 33.9 bits (76), Expect = 0.095, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 214 PKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAA 273 P + V K G G + L L + PIFS++ ++E V +E F++ K+ + G Sbjct: 43 PTLAMVKKNGGSDKRGEKKLTLEEFLPIFSQIKKEKE-VGTLEDFMEGLKVYDKAENGTM 101 Query: 274 LAAVYSHVIQKL 285 LAA +HV+ L Sbjct: 102 LAAELAHVLLSL 113 >2BHS-A nrPDB Length = 303 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 40/183 (21%), Positives = 78/183 (42%), Gaps = 14/183 (7%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSA 65 TP+ + G+ V+LK++ P+GS K R K+G + +++ Sbjct: 10 NTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATS 69 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVG--ELLDEAFELAKAL 123 GN G+A A A G +++P ++ GA + +V + ++ A +LA + Sbjct: 70 GNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALEM 129 Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGA----IALSVGGGGLLCGVVQG 179 A G + + F++P H + +W++ G S+G G + GV + Sbjct: 130 ANRGEGKL-LDQFNNPDNPYAHYTTT---GPEIWQQTGGRITHFVSSMGTTGTITGVSRF 185 Query: 180 LQE 182 ++E Sbjct: 186 MRE 188 >5XCN-X nrPDB Length = 350 Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Query: 26 SVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAGNAGMAAAYAARQLGV 81 +V +K++ PS S K R + + K G V +++GN G+A AY A G Sbjct: 61 NVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGY 120 Query: 82 PATIVVPSTTPALTIERLK 100 T+ +P T +++ER + Sbjct: 121 KITLTMPET---MSLERKR 136 >6HUL-B nrPDB Length = 425 Score = 32.7 bits (73), Expect = 0.23, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 9/83 (10%) Query: 11 TPIRDSMALSKMAGT--SVYLKMDSAQPSGSFKIRGI---GHFCKRWAKQGCAHFVCSS- 64 TP+ + L + T +Y K + A P+GS KI +F K ++G H V + Sbjct: 76 TPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAK---EEGIEHVVTETG 132 Query: 65 AGNAGMAAAYAARQLGVPATIVV 87 AG G A A AA + +TI + Sbjct: 133 AGQWGTAVALAASMYNMKSTIFM 155 >3PC3-A nrPDB Length = 527 Score = 32.0 bits (71), Expect = 0.37, Method: Compositional matrix adjust. Identities = 40/174 (22%), Positives = 73/174 (41%), Gaps = 26/174 (14%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAGNAGMAAAYAARQLGVP 82 +Y K + P GS K R + +QG + ++GN G+ A A G Sbjct: 79 MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYK 138 Query: 83 ATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-------LAKALAKNNPGWVYIPP 135 IV+P + L+ GA K++ + A++ +A+ L + P + + Sbjct: 139 CIIVMPEKMSNEKVSALRTLGA--KIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQ 196 Query: 136 FD---DPLI-WEGHASIVKELKETLWE---KPGAIALSVGGGGLLCGVVQGLQE 182 + +PL ++G A+ E LW+ K I +S G G + G+ + ++E Sbjct: 197 YRNAGNPLAHYDGTAA------EILWQLDNKVDMIVVSAGTAGTISGIGRKIKE 244 >4LMB-A nrPDB Length = 322 Score = 31.6 bits (70), Expect = 0.49, Method: Compositional matrix adjust. Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 13/123 (10%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH-----FVCSSAGNAGMAAAYAARQLGV 81 + +K++S P+ S K R + G H V ++GN G+A A A G Sbjct: 39 IVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTILVEPTSGNTGIALAMVAAAKGY 98 Query: 82 PATIVVPSTTPALTIER---LKNEGATVKVV--GELLDEAFELAKALAKNNPGWVYIPPF 136 + +P T +++ER LK GA +++ + ++ A A+ + +N P + F Sbjct: 99 RLVLTMPET---MSLERRAMLKAYGAQLELTPGSQGMEGAITRAEEIVENTPNAYSLQQF 155 Query: 137 DDP 139 +P Sbjct: 156 RNP 158 >6EQN-B nrPDB Length = 425 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 7/86 (8%) Query: 11 TPIRDSMALSKMAGTSV--YLKMDSAQPSGSFKIR-GIGHFCKRWAKQGCAHFVCSS--A 65 TPI + L + G ++ YLKM+S +GS KI + H +AK A FV + A Sbjct: 76 TPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVY--YAKLDNAKFVTTETGA 133 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTT 91 G G + A A+ + A I + T+ Sbjct: 134 GQWGSSVALASALFRMKAHIFMVRTS 159 >3VBE-A nrPDB Length = 344 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 21/150 (14%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFC-----KRWAKQGCAHFVCSS 64 +TP+ +++ G V +K + QP+ S K R K G + + Sbjct: 35 RTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKNLITPGKTTLIEPT 94 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIER---LKNEGATV------KVVGELLDE 115 +GN G++ A+ A G + +PS T ++ER ++ GA + K +G + + Sbjct: 95 SGNMGISMAFMAAMKGYKMVLTMPSYT---SLERRVTMRAFGAELILTDPAKGMGGTVKK 151 Query: 116 AFELAKALAKNNPGWVYIPPFDDPLIWEGH 145 A+E L +N P + F +P + H Sbjct: 152 AYE----LLENTPNAHMLQQFSNPANTQVH 177 >4I1Y-A nrPDB Length = 314 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 38/150 (25%), Positives = 62/150 (41%), Gaps = 12/150 (8%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66 TP+ ++ A V K++S P+GS K R K G + ++G Sbjct: 18 TPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGLIKPDTIILEPTSG 77 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIER---LKNEGATVKVV--GELLDEAFELAK 121 N G+A A + G + +P T ++IER L+ GA + + E + A A+ Sbjct: 78 NTGIALAMVSAARGYKCVLTMPDT---MSIERRMLLRAYGAELVLTPGAEGMAGAIAKAE 134 Query: 122 ALAKNNPGWVYIPPFDDPLIWEGHASIVKE 151 LAK + + F++P HA E Sbjct: 135 ELAKTDDRYFIPQQFENPANPAVHAVTTAE 164 >5XEM-A nrPDB Length = 310 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 7/81 (8%) Query: 24 GTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAGNAGMAAAYAARQL 79 G +Y+K++ + P S K R + K+G + +++GN G+ A Sbjct: 29 GNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLIDKDTVIIEATSGNTGIGLAMICAVK 88 Query: 80 GVPATIVVPSTTPALTIERLK 100 IV+P T ++IER++ Sbjct: 89 NYKLKIVMPDT---MSIERIQ 106 >1OZV-A nrPDB Length = 444 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 260 DDEKIL---VEPACGAALAAVYSHVIQKLQL-EGNLRTPLPSLVVIVCGGSNISLAQLRA 315 D+E++L V AC +ALA ++ + Q +L EGNL + L ++ V + G + L Q+ Sbjct: 347 DNEELLCKAVREACKSALAGYHTTIEQDRELKEGNLDSRL-AIAVGIREGEKMVLQQIDG 405 Query: 316 LKEQ 319 + EQ Sbjct: 406 IFEQ 409 >2JC3-A nrPDB Length = 303 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 29/136 (21%), Positives = 62/136 (45%), Gaps = 7/136 (5%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSA 65 TP+ + G+ +++K++ P+GS K R K+G + +++ Sbjct: 10 NTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATS 69 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVG--ELLDEAFELAKAL 123 GN G+A A A G +++P ++ GA + +V + ++ A +LA A+ Sbjct: 70 GNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALAM 129 Query: 124 AKNNPGWVYIPPFDDP 139 ++ G + + F++P Sbjct: 130 SERGEGKL-LDQFNNP 144 >3SS9-X nrPDB Length = 442 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/90 (21%), Positives = 42/90 (46%) Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKAL 123 S GN G++ + ++G T+ + + A +L++ G TV + A E + Sbjct: 167 STGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKA 226 Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELK 153 A+++P +I + ++ G++ + LK Sbjct: 227 AQSDPNCFFIDDENSRTLFLGYSVAGQRLK 256 >3R0X-A nrPDB Length = 448 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/90 (22%), Positives = 41/90 (45%) Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKAL 123 S GN G++ + +G T+ + + A +L++ G TV + A E + Sbjct: 165 STGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKA 224 Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELK 153 A+++P +I + ++ G+A + LK Sbjct: 225 AQSDPNCFFIDDENSRTLFLGYAVAGQRLK 254 >1X1Q-A nrPDB Length = 418 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 57/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%) Query: 11 TPIRDSMALSKM-AGTSVYLKMDSAQPSGSFKIR---GIGHFCKRWAKQGCAHFVCSSAG 66 TP+ + LS+ G V+LK + +G+ KI G +R K+ + AG Sbjct: 78 TPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRV--IAETGAG 135 Query: 67 NAGMAAAYAARQLGVPATIVVPS---TTPALTIERLKNEGATVKVVG----ELLDEAFEL 119 G++ A A G+ + + AL + R+K GA V+ V L D E Sbjct: 136 QHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEA 195 Query: 120 AKALAKNNPGWVYI-----PPFDDPLIWEGHASIV-KELK----ETLWEKPGAIALSVGG 169 + N YI P P++ S++ +E+K E P A+ +VGG Sbjct: 196 IRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFGRLPDALIAAVGG 255 Query: 170 GGLLCGVVQGLQEVGWGDVPVIAMETFG---AHSFHAATT-AGK 209 G G+ + G +I +E G + HAA+ AGK Sbjct: 256 GSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGK 299 >2EGU-A nrPDB Length = 308 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 26 SVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAGNAGMAAAYAARQLGV 81 VYLK++ P S K R + K G V ++GN G+ A A G Sbjct: 30 DVYLKLEFMNPGSSVKDRIALAMIEAAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGY 89 Query: 82 PATIVVPSTTPALTIER 98 A +V+P T +++ER Sbjct: 90 KAVLVMPDT---MSLER 103 >1E5X-A nrPDB Length = 486 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 9/132 (6%) Query: 62 CSSAGNAGMAAAYAARQLGVPATIVVPSTTPALT--IERLKNEGATVKVVGELLDEAFEL 119 C+S G+ A + G+P+ + +P+ ++ ++ + N GA V + D +L Sbjct: 189 CASTGDTSAALSAYCASAGIPSIVFLPANKISMAQLVQPIAN-GAFVLSIDTDFDGCMKL 247 Query: 120 AKALAKNNPGWVYIPPFDDPLIWEGHASIVKE-LKETLWEKPGAIALSVGGGGLLCGVVQ 178 + + P +Y+ + L EG + E L++ W+ P + + G G + + Sbjct: 248 IREITAELP--IYLANSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYK 305 Query: 179 GL---QEVGWGD 187 G QE+G D Sbjct: 306 GFKMCQELGLVD 317 >4C2K-A nrPDB Length = 417 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 72 AAYAARQLGVPATIVVPSTTPALTIERLKNEG 103 A Y AR +G+ + +P TPALTI RL G Sbjct: 86 AIYLARHVGL--RVGIPKETPALTINRLCGSG 115 >2OB5-A nrPDB Length = 153 Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 172 LLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKAL 223 L V+ L+ +G GD VI+ F + S TT GK++ + + S A+A+ Sbjct: 13 LNADVLHALRAMGHGDTLVISDTNFPSDSVARQTTVGKVLHIDNV-SAARAM 63 >3T4P-A nrPDB Length = 334 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 15/133 (11%) Query: 16 SMALSKMAGTS--VYLKMDSAQPSGSFKIR-GIGHFCKRWAK----QGCAHFVCSSAGNA 68 ++ L+K+ T V LKM+ P S K R G + K + G + V SS+GN Sbjct: 24 ALYLNKLNNTKAKVVLKMECENPMASVKDRLGFAIYDKAEKEGKLIPGKSIVVESSSGNT 83 Query: 69 GMAAAYAARQLGVPATIVVPSTTPALTIER---LKNEGATVKVVGELL--DEAFELAKAL 123 G++ A+ G I +P + +++ER L+ GA V + L A +AK + Sbjct: 84 GVSLAHLGAIRGYKVIITMPES---MSLERRCLLRIFGAEVILTPAALGMKGAVAMAKKI 140 Query: 124 AKNNPGWVYIPPF 136 NP V F Sbjct: 141 VAANPNAVLADQF 153 >5H2U-A nrPDB Length = 267 Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 26/53 (49%) Query: 72 AAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 A YA +G P I+ +E L++ V V ELLD A+++A+ + Sbjct: 66 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMC 118 >1F8S-A nrPDB Length = 498 Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 22/46 (47%) Query: 59 HFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGA 104 H V AG AG++AAY G T++ S P + +NE A Sbjct: 35 HVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEA 80 >1N5D-A nrPDB Length = 288 Score = 28.1 bits (61), Expect = 6.2, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 215 KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEK 263 ++ +V+ GV+ + + +L Q+ SE I+++E V + KFV+D K Sbjct: 133 RVVNVSSTEGVRALNECSPELQQKFK--SETITEEELVGLMNKFVEDTK 179 >5OHX-A nrPDB Length = 504 Score = 27.3 bits (59), Expect = 8.9, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 27 VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCS----SAGNAGMAAAYAARQLGVP 82 +Y K + P GS K R + +G C+ ++GN G+ A AA G Sbjct: 64 IYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYK 123 Query: 83 ATIVVPSTTPALTIERLKNEGATV 106 IV+P I L GA + Sbjct: 124 CIIVMPEKMSDEKISTLYALGAKI 147 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4H27-A nrPDB 420 e-118 1PWH-A nrPDB 363 e-101 2RKB-A nrPDB 309 1e-84 5C3U-A nrPDB 301 2e-82 5X2L-A nrPDB 287 4e-78 3L6C-A nrPDB 267 5e-72 3IAU-A nrPDB 267 6e-72 1TDJ-A nrPDB 261 3e-70 5YBW-A nrPDB 258 3e-69 6NMX-A nrPDB 257 5e-69 2D1F-A nrPDB 250 4e-67 1V71-A nrPDB 247 6e-66 2ZSJ-A nrPDB 246 1e-65 1UIN-A nrPDB 234 4e-62 5JJC-A nrPDB 232 2e-61 5CVC-A nrPDB 228 2e-60 1VE5-A nrPDB 213 1e-55 2GN1-A nrPDB 204 4e-53 5D84-A nrPDB 203 1e-52 5XW3-A nrPDB 195 2e-50 1J0B-A nrPDB 146 1e-35 5YGR-A nrPDB 145 3e-35 5I7O-A nrPDB 142 3e-34 Sequences not found previously or not previously below threshold: 4COO-A nrPDB 166 9e-42 1M54-A nrPDB 166 1e-41 5MMS-A nrPDB 165 3e-41 5OHX-A nrPDB 162 3e-40 6AHI-A nrPDB 160 7e-40 3FCA-A nrPDB 157 4e-39 6C2H-A nrPDB 155 2e-38 3PC3-A nrPDB 147 4e-36 2JC3-A nrPDB 146 2e-35 2BHS-A nrPDB 145 2e-35 4OFX-A nrPDB 144 6e-35 5XEM-A nrPDB 138 3e-33 2EFY-A nrPDB 138 3e-33 4LMA-A nrPDB 137 5e-33 3VBE-A nrPDB 137 8e-33 5XA2-A nrPDB 136 9e-33 2Q3D-A nrPDB 136 2e-32 5J5V-A nrPDB 133 8e-32 5B1I-A nrPDB 131 5e-31 4AEC-A nrPDB 131 5e-31 1E5X-A nrPDB 131 6e-31 2EGU-A nrPDB 130 9e-31 2PQM-A nrPDB 129 2e-30 4I1Y-A nrPDB 127 5e-30 4LMB-A nrPDB 123 1e-28 2ISQ-A nrPDB 122 1e-28 4D9G-A nrPDB 120 7e-28 3X43-A nrPDB 119 2e-27 3T4P-A nrPDB 114 8e-26 5XCN-X nrPDB 110 1e-24 5B55-A nrPDB 107 6e-24 4D9F-A nrPDB 99 2e-21 3VSD-A nrPDB 92 4e-19 5EY5-B nrPDB 91 4e-19 5OCW-B nrPDB 90 2e-18 5KIN-B nrPDB 89 3e-18 1X1Q-A nrPDB 84 7e-17 3SS9-X nrPDB 84 1e-16 6AMI-A nrPDB 84 1e-16 1RQX-A nrPDB 82 3e-16 5KZM-B nrPDB 80 1e-15 4NEG-A nrPDB 78 6e-15 6HUL-B nrPDB 77 7e-15 3R0X-A nrPDB 76 2e-14 1CX9-B nrPDB 72 3e-13 6EQN-B nrPDB 64 6e-11 1VB3-A nrPDB 57 8e-09 4PET-A nrPDB 32 0.49 2HQ1-A nrPDB 30 1.2 6EKH-Y nrPDB 30 1.6 2VCY-A nrPDB 30 1.7 1F8F-A nrPDB 30 1.8 3ZRR-A nrPDB 29 2.1 2G2R-H nrPDB 29 2.3 5CM6-A nrPDB 29 3.2 1JWB-B nrPDB 28 5.3 6OMZ-A nrPDB 28 5.5 3DAH-A nrPDB 28 6.8 2PNF-A nrPDB 28 6.9 4EVZ-A nrPDB 27 7.7 5TNX-A nrPDB 27 8.5 >4H27-A nrPDB Length = 364 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 326/328 (99%), Positives = 327/328 (99%) Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF Sbjct: 37 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 96 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120 VCSS+GNAGMAAAYAARQLGVPATIVVP TTPALTIERLKNEGATVKVVGELLDEAFELA Sbjct: 97 VCSSSGNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVVGELLDEAFELA 156 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL Sbjct: 157 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 216 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP Sbjct: 217 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 276 Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV Sbjct: 277 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 336 Query: 301 IVCGGSNISLAQLRALKEQLGMTNRLPK 328 IVCGGSNISLAQLRALKEQLGMTNRLPK Sbjct: 337 IVCGGSNISLAQLRALKEQLGMTNRLPK 364 >1PWH-A nrPDB Length = 327 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 274/326 (84%), Positives = 293/326 (89%) Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60 M + E LHVKTP+RDSMALSK+AGTSV+LKMDS+QPSGSFKIRGIGH CK AKQGC HF Sbjct: 1 MAAQESLHVKTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRGIGHLCKMKAKQGCKHF 60 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120 VCSSAGNAGMA AYAAR+LG+PATIVVPSTTPALTIERLKNEGATV+VVGE+LDEA +LA Sbjct: 61 VCSSAGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVVGEMLDEAIQLA 120 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 KAL KNNPGWVYI PFDDPLIWEGH S+VKELKETL KPGAI LSVGGGGLLCGVVQGL Sbjct: 121 KALEKNNPGWVYISPFDDPLIWEGHTSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQGL 180 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240 +EVGW DVP+IAMETFGAHSFHAA GKLV+LPKITSVAKALGV TVGAQ LKLF EHP Sbjct: 181 REVGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKITSVAKALGVNTVGAQTLKLFYEHP 240 Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 IFSEVISDQEAV AIEKFVDDEKILVEPACGAALAAVYS V+ +LQ E L+TPL SLVV Sbjct: 241 IFSEVISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEARLQTPLASLVV 300 Query: 301 IVCGGSNISLAQLRALKEQLGMTNRL 326 IVCGGSNISLAQL+ALK QLG+ L Sbjct: 301 IVCGGSNISLAQLQALKAQLGLNELL 326 >2RKB-A nrPDB Length = 318 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 196/318 (61%), Positives = 249/318 (78%), Gaps = 1/318 (0%) Query: 4 GEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCS 63 EP HV TP+ +S ALS++AG V+LK ++ QPSGSFKIRGIGHFC+ AK+GC H VCS Sbjct: 1 QEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCS 60 Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKAL 123 S GNAG+AAAYAAR+LG+PATIV+P +T ++RL+ EGA V++ G++ DEA A+ L Sbjct: 61 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQEL 120 Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEV 183 AK + GW +PPFD PLIW+GHAS+V+ELK L PGA+ L+VGGGGLL GVV GL EV Sbjct: 121 AKRD-GWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEV 179 Query: 184 GWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFS 243 GW VP+IAMET GAH F+AA TAGKLV+LP ITSVAK+LG KTV A+AL+ Q I S Sbjct: 180 GWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHS 239 Query: 244 EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVC 303 EV+ D EAV+A+++ +DDE++LVEPACGAALAA+YS ++++LQ EG L L S+VVIVC Sbjct: 240 EVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVC 299 Query: 304 GGSNISLAQLRALKEQLG 321 GG+NI+ +L+ALK LG Sbjct: 300 GGNNINSRELQALKTHLG 317 >5C3U-A nrPDB Length = 366 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 133/318 (41%), Positives = 195/318 (61%), Gaps = 8/318 (2%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWA--KQGCAHFVC 62 + LHV TP+ + L+K +V+LKM++ QPSGS K+RGIG FC + + FVC Sbjct: 16 QSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQTRGTNIQFVC 75 Query: 63 SSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKA 122 S N +A +Y ARQLGV A IVVP T + ++ +G+ + + GE A A+ Sbjct: 76 GSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLILYGENWTAAEVHARK 135 Query: 123 LAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWE-KPGAIALSVGGGGLLCGVVQGLQ 181 L + N +Y+P D LIW+GH++IV+ELK L + P AI VGGGGLL GV+ GLQ Sbjct: 136 LVRRN--GIYVPSSDHALIWQGHSTIVQELKTQLNDNPPAAIICPVGGGGLLNGVIMGLQ 193 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 E W DVPVIA+ET G+++F A+ AG+LV + K ++A +L K V +++L+L HP+ Sbjct: 194 EADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLISKAVSSKSLELSLNHPV 253 Query: 242 FSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 +SD A A+ F +D K+LVE + GAAL+ Y+H+I+ + +P +VV+ Sbjct: 254 VPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRDILPS---LSPAKDVVVL 310 Query: 302 VCGGSNISLAQLRALKEQ 319 V GGS+ISLA L +++ Sbjct: 311 VTGGSDISLAHLDEYRKK 328 >5X2L-A nrPDB Length = 348 Score = 287 bits (734), Expect = 4e-78, Method: Composition-based stats. Identities = 82/316 (25%), Positives = 143/316 (45%), Gaps = 17/316 (5%) Query: 9 VKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH----FCKRWAKQGCAHFVCSS 64 TP+ S L+++ G +++ K + Q +GSFKIRG + ++ V S Sbjct: 24 HLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHS 83 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 +GN G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E Sbjct: 84 SGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-VYCEPSDESRENVAKRV 142 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 + + P +P + G +I E+ + A+ + VGGGG+L G+ ++ + Sbjct: 143 TEETEGIMVHPNQEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMLAGIAITVKALK 201 Query: 185 WGDVPVIAMETFGAHSFHAATTAGKL-VSLPKITSVAKALGVKTVGAQALKLFQEHPIFS 243 V V A E A + + GKL +L ++A + ++G + ++ Sbjct: 202 -PSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKS-SIGLNTWPIIRDLVDDI 259 Query: 244 EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVC 303 +++ E A + + K+L+EP G +AAV S Q + +P + IV Sbjct: 260 FTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTV-------SPEVKNICIVL 312 Query: 304 GGSNISL-AQLRALKE 318 G N+ L + + +K+ Sbjct: 313 SGGNVDLTSSITWVKQ 328 >3L6C-A nrPDB Length = 339 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 22/319 (6%) Query: 8 HVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH----FCKRWAKQGCAHFVCS 63 TP+ S L+++AG +++ K + Q +GSFKIRG + + V Sbjct: 23 VHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTH 82 Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-LAKA 122 S+GN G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E +A+ Sbjct: 83 SSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASI-VYSEPSDESRENVAQR 141 Query: 123 LAKNNPGWVYIPPFDDPLIWEGHASIVKELKET--LWEKPGAIALSVGGGGLLCGVVQGL 180 + + G + + P +P + G +I E+ L + G + ++ L Sbjct: 142 IIQETEG-ILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTL 200 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKL-VSLPKITSVAKALGVKTVGAQALKLFQEH 239 + V V A E A + + G+L +L ++A + ++G + ++ Sbjct: 201 K----PSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKS-SIGLNTWPIIRDL 255 Query: 240 PIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLV 299 +++ E A + + K+L+EP G LAAV S Q + +P + Sbjct: 256 VDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTV-------SPEVKNI 308 Query: 300 VIVCGGSNISLAQLRALKE 318 IV G N+ L L +K+ Sbjct: 309 CIVLSGGNVDLTSLSWVKQ 327 >3IAU-A nrPDB Length = 366 Score = 267 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 86/316 (27%), Positives = 156/316 (49%), Gaps = 14/316 (4%) Query: 9 VKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCA-HFVCSSAGN 67 +++P+ + LS G + Y+K + Q SFK+RG + +++ + +SAGN Sbjct: 59 IESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELDKGVITASAGN 118 Query: 68 AGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNN 127 A A ++L A IV+P+TTP + I+ ++ G V + G+ DEA A L++ + Sbjct: 119 HAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTHALELSEKD 178 Query: 128 PGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD 187 G YIPPFDDP + +G +I E+ L + A+ + VGGGGL+ GV +++ + Sbjct: 179 -GLKYIPPFDDPGVIKGQGTIGTEINRQLKD-IHAVFIPVGGGGLIAGVATFFKQIA-PN 235 Query: 188 VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS 247 +I +E +GA S + G V L + + A + V VG QE +++ Sbjct: 236 TKIIGVEPYGAASMTLSLHEGHRVKLSNVDTFADGVAVALVGEYTFAKCQELIDGMVLVA 295 Query: 248 DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHV-IQKLQLEGNLRTPLPSLVVIVCGGS 306 + AAI+ D+ + ++E + A+A ++ K++ E +V + G+ Sbjct: 296 NDGISAAIKDVYDEGRNILETSGAVAIAGAAAYCEFYKIKNE---------NIVAIASGA 346 Query: 307 NISLAQLRALKEQLGM 322 N+ ++L + E G+ Sbjct: 347 NMDFSKLHKVTELAGL 362 >1TDJ-A nrPDB Length = 514 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 84/316 (26%), Positives = 151/316 (47%), Gaps = 12/316 (3%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH-FVCSSAGNAG 69 TP++ LS + +K + QP SFK+RG ++ AH + +SAGN Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHA 91 Query: 70 MAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNPG 129 A+++ +LGV A IV+P+ T + ++ ++ G V + G DEA A L++ G Sbjct: 92 QGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQ-G 150 Query: 130 WVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVP 189 + ++PPFD P++ G ++ EL + + + VGGGGL GV ++++ + Sbjct: 151 FTWVPPFDHPMVIAGQGTLALELLQQ-DAHLDRVFVPVGGGGLAAGVAVLIKQLM-PQIK 208 Query: 190 VIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQ 249 VIA+E + AA AG V LP++ A+ + VK +G + +L QE+ + Sbjct: 209 VIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSD 268 Query: 250 EAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNIS 309 AA++ +D + + EP+ ALA + ++ L + G+N++ Sbjct: 269 AICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERL--------AHILSGANVN 320 Query: 310 LAQLRALKEQLGMTNR 325 LR + E+ + + Sbjct: 321 FHGLRYVSERCELGEQ 336 >5YBW-A nrPDB Length = 329 Score = 258 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 83/314 (26%), Positives = 139/314 (44%), Gaps = 19/314 (6%) Query: 11 TPIRDSMALSKM----AGTSVYLKMDSAQPSGSFKIRGIGH--FCKRWAKQGCAHFVCSS 64 TP+ S +M AG Y K ++ Q +GSFK RG + C + A V S Sbjct: 25 TPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGSFKARGALNAILCALEREPSLAGVVTHS 84 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 +GN G A A+A+++ GV +VVP T P + + ++N GA V E + LA Sbjct: 85 SGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDAMENYGAEVVKCEPNPTSRKETCEGLA 144 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 K+ G+ YI DD + G +I EL + + AI +SV GG+ G+ + Sbjct: 145 KS-RGYKYISSSDDYDVIAGQGTIALELLQQQPDL-DAILVSVSAGGMASGICVYTKNTK 202 Query: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPK--ITSVAKALGVKTVGAQALKLFQEHPIF 242 D+ V +E G + +L P + ++A + ++ G + + E P Sbjct: 203 -SDLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIADGIILQQCGNKTWPIILELPEK 261 Query: 243 SEV-ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 + +++ V A+ K+++E A GA +AA + Q E + +I Sbjct: 262 EVITVNNDNIVEAMRFVFARMKLVIEAAAGATVAAAMTERFQNFHPEAK------KVGII 315 Query: 302 VCGGSNISLAQLRA 315 +CGG N+ + +L Sbjct: 316 LCGG-NVDIEKLPW 328 >6NMX-A nrPDB Length = 354 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 66/299 (22%), Positives = 131/299 (43%), Gaps = 11/299 (3%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAG 69 TP+ LS+ G +++K + P+GSFK RG+ + ++G +C+S GN Sbjct: 30 NTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEGNDTIMCASTGNTS 89 Query: 70 MAAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKALAKNNP 128 AAA A + + +++P+ A + + GA + + D+A ++ +++ + +P Sbjct: 90 AAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDGNFDDALKIVRSICEKSP 149 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD- 187 + + +P EG + E+ E L E P +A+ VG G + +G +E + Sbjct: 150 --IALVNSVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYWKGFKEYHEKNG 207 Query: 188 VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVIS 247 + M F A AA +++ P+ + A +G +A+K +E + ++ Sbjct: 208 TSLPKMRGFEAEG-SAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAEESNGKIDEVT 266 Query: 248 DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGS 306 D E + A + +E + EP A++A V V + +V ++ G Sbjct: 267 DDEILHAYQLIAREEGVFAEPGSCASIAGVLKQV------KSGEIPKGSKVVAVLTGNG 319 >2D1F-A nrPDB Length = 360 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 73/298 (24%), Positives = 126/298 (42%), Gaps = 9/298 (3%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGM 70 TP+ + LSK G +++LK++ P+GSFK RG+ G +C+S GN Sbjct: 39 TPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSA 98 Query: 71 AAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKALAKNNPG 129 +AA A + G+ +++P A+ + + GA + + D+ ELA+ +A + P Sbjct: 99 SAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPT 158 Query: 130 WVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVP 189 + +P+ EG + E+ + L P AL VG G + +G E + Sbjct: 159 ISLV-NSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLI 217 Query: 190 VIAMETFGAHSFHAATTA-GKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISD 248 G + AA G+ VS P+ + A +G A++ Q+ SD Sbjct: 218 DKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASD 277 Query: 249 QEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGS 306 +E +AA E + VEPA A++A + + + ++V V G Sbjct: 278 EEILAAYHLVARVEGVFVEPASAASIAGLLKAI------DDGWVARGSTVVCTVTGNG 329 >1V71-A nrPDB Length = 323 Score = 247 bits (630), Expect = 6e-66, Method: Composition-based stats. Identities = 71/308 (23%), Positives = 126/308 (40%), Gaps = 16/308 (5%) Query: 7 LHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAK-QGCAHFVCSSA 65 KTP+ S ++K V+ K ++ Q G+FK RG + + + Q A + S+ Sbjct: 23 FANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQRKAGVLTFSS 82 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 125 GN A A +A+ LG+PA I++P P + K G V + D+ ++AK +++ Sbjct: 83 GNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISE 142 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGW 185 G IPP+D P + G + KEL E + AL V GG L + Sbjct: 143 RE-GLTIIPPYDHPHVLAGQGTAAKELFEEVGPLD---ALFVCLGGGGLLSGSALAARHF 198 Query: 186 -GDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 244 + V +E + + G +V + ++A + +G + +E Sbjct: 199 APNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDIL 258 Query: 245 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304 +SD+E + ++ + KI+VEP + AA + I+ Sbjct: 259 TVSDEELIDCLKFYAARMKIVVEPTGCLSFAAA----------RAMKEKLKNKRIGIIIS 308 Query: 305 GSNISLAQ 312 G N+ + + Sbjct: 309 GGNVDIER 316 >2ZSJ-A nrPDB Length = 352 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 72/291 (24%), Positives = 123/291 (42%), Gaps = 6/291 (2%) Query: 7 LHVKTPIRDSMALSKMAGTS--VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS 64 TP+ ++ L++ G +YLK + P+GSFK RG+ + + G +C+S Sbjct: 27 YEGNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKAVEAGKRAVICAS 86 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKAL 123 GN +AA A + G+ A +++P A+ + + GA V + D+A + + + Sbjct: 87 TGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVLAIQGTFDDALNIVRKI 146 Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEV 183 +N P V I +P EG + E+ +TL E P + VG G + +G + Sbjct: 147 GENFP--VEIVNSVNPYRIEGQKTAAFEICDTLGEAPDYHFIPVGNAGNITAYWKGFKIY 204 Query: 184 GWGDVPVIAMETFGAHSFHAAT-TAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 G + AA G + P+ + A +G ALK QE Sbjct: 205 YEEGKITKLPRMMGWQAEGAAPIVKGYPIKNPQTIATAIKIGNPYSWKSALKAAQESGGK 264 Query: 243 SEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRT 293 + +SD E + A + E + EPA A++A + V + G + T Sbjct: 265 IDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLIKLVREGFFKGGEVVT 315 >1UIN-A nrPDB Length = 351 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 80/313 (25%), Positives = 131/313 (41%), Gaps = 12/313 (3%) Query: 11 TPIRDS--MALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNA 68 TP+ ++ G +Y K + P+GSFK RG+ + + G C+S GN Sbjct: 29 TPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGGAQAVACASTGNT 88 Query: 69 GMAAAYAARQLGVPATIVVPSTTPAL-TIERLKNEGATVKVVGELLDEAFELAKALAKNN 127 +AA A + G+ A +V+P+ AL + + GA + V D+A L + L + Sbjct: 89 AASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEGNFDDALRLTQKLTEAF 148 Query: 128 PGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGD 187 P V + +P EG ++ E+ + L + P AL VG G + G + Sbjct: 149 P--VALVNSVNPHRLEGQKTLAFEVVDELGDAPHYHALPVGNAGNITAHWMGYKAYHALG 206 Query: 188 VPVIAMETFGAHSFHAATTA-GKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVI 246 G + AA G+ V P+ + A +G A++ +E E + Sbjct: 207 KAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAIRIGNPASWQGAVRAKEESGGVIEAV 266 Query: 247 SDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGS 306 +D+E + A +E I EPA AA+A V+ KL EG L P ++V+ + G Sbjct: 267 TDEEILFAYRYLAREEGIFCEPASAAAMAGVF-----KLLREGRLE-PESTVVLTLTGHG 320 Query: 307 NISLAQLRALKEQ 319 A + E Sbjct: 321 LKDPATAERVAEL 333 >5JJC-A nrPDB Length = 342 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 76/318 (23%), Positives = 133/318 (41%), Gaps = 29/318 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 TP+ S++ G +Y K + P S K R + + K+G V +A Sbjct: 11 NTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRPGGVIVEGTA 70 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--------GELLDEAF 117 GN G+ A+ LG IV+P T + L+ GA + V + + Sbjct: 71 GNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRNPNNAVRLSG 130 Query: 118 ELAKALAKNNP-GWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCG 175 LA+ LAK P G ++ FD+ + + H + +E+ ++ +VG GG L G Sbjct: 131 RLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAAVGSGGTLAG 190 Query: 176 VVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKL 235 GL+E ++ + + GA + HA T G+L + + S+ + +G + A L+ Sbjct: 191 TAIGLKERNH-NIKIALADPHGA-ALHAFYTTGELKA--EGDSITEGIGQGRITAN-LEG 245 Query: 236 FQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPL 295 F P FS I D EA+ + V++E + + + G +A P Sbjct: 246 F--TPDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGAI--------RLAKDLGPG 295 Query: 296 PSLVVIVCGGSNISLAQL 313 ++V ++C N ++L Sbjct: 296 HTIVTVLCDYGNRYQSKL 313 >5CVC-A nrPDB Length = 346 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 82/309 (26%), Positives = 137/309 (44%), Gaps = 10/309 (3%) Query: 6 PLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH-FCKRWAKQGCAHFVCSS 64 P +TP+ S ++ M G ++ K + Q +G+FKIRG + +Q V S Sbjct: 32 PYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSIFALDDEQVSKGVVTHS 91 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 +GN A A AA+ G+PA IV+P PA +E +K G + + E+ E Sbjct: 92 SGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGHII-WSDASIESREYVSKRV 150 Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184 + G V I P + G ++ EL E + E I + + GGGL+ GV + + Sbjct: 151 QEETGAVLIHPINSKYTISGQGTVSLELLEQVPE-IDTIIVPISGGGLISGVALAAKAIN 209 Query: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 244 + ++A E GA + AGK+++LP ++A L +G + ++ Sbjct: 210 -PSIRILAAEPKGADDSAQSKAAGKIITLPSTNTIADGL-RAFLGDLTWPVVRDLVDDVI 267 Query: 245 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304 V+ D V A++ + K+ VEP+ LAA S ++ + S + I+ Sbjct: 268 VVDDTAIVDAMKMCYEILKVAVEPSGAIGLAAALSDEFKQ-----SSAWHESSKIGIIVS 322 Query: 305 GSNISLAQL 313 G N+ L L Sbjct: 323 GGNVDLGTL 331 >1VE5-A nrPDB Length = 311 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 84/310 (27%), Positives = 132/310 (42%), Gaps = 19/310 (6%) Query: 6 PLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSA 65 P +TP+ S L + G + LK + Q +GSFK RG K A + + S+ Sbjct: 16 PYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGA--LSKALALENPKGLLAVSS 73 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 125 GN AYAA+ LGV A +V+P + GA V G E+A+AL + Sbjct: 74 GNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVDRGVTAKNREEVARAL-Q 132 Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEK---PGAIALSVGGGGLLCGVVQGLQE 182 G+ I PFDDPL+ G + EL PGA+ VGGGGLL G+ ++ Sbjct: 133 EETGYALIHPFDDPLVIAGQGTAGLELLAQAGRMGVFPGAVLAPVGGGGLLAGLATAVKA 192 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLP-KITSVAKALGVKTVGAQALKLFQEHPI 241 + + V+ +E A + AG+++ L + A + ++G + + +E Sbjct: 193 LSPTTL-VLGVEPEAADDAKRSLEAGRILRLEAPPRTRADGVRTLSLGERTFPILRERVD 251 Query: 242 FSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 +S++ + A K +VEP LAAV H + LP + + Sbjct: 252 GILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVLEHGAR-----------LPQTLAL 300 Query: 302 VCGGSNISLA 311 + G N + Sbjct: 301 LLSGGNRDFS 310 >2GN1-A nrPDB Length = 342 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 65/309 (21%), Positives = 127/309 (41%), Gaps = 12/309 (3%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGH-FCKRWAKQGCAHFVCSSAGNA 68 KT + S S+ ++LK ++ Q +GSFKIRG + + V SAGN Sbjct: 40 KTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKGVVACSAGNH 99 Query: 69 GMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNP 128 + + LG+ +V+P P + + A V + G+ ++ + + Sbjct: 100 AQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVETE- 158 Query: 129 GWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDV 188 G ++IPP+DDP + G +I E+ E L++ I +GGGGL+ G+ ++ + + Sbjct: 159 GRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIV-PIGGGGLIAGIAIAIKSIN-PTI 216 Query: 189 PVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISD 248 VI ++ H A+ G++ + ++A V G ++ +E ++S+ Sbjct: 217 KVIGVQAENVHGMAASYYTGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSE 276 Query: 249 QEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNI 308 E ++ + K++ E + L V + G NI Sbjct: 277 DEIRNSMIALIQRNKVITE--------GAGALACAALLSGKLDSHIQNRKTVSIISGGNI 328 Query: 309 SLAQLRALK 317 L+++ + Sbjct: 329 DLSRVSQIT 337 >5D84-A nrPDB Length = 326 Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 64/304 (21%), Positives = 124/304 (40%), Gaps = 34/304 (11%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 +TP+ L V+ K++ P GS K R + + K G H + S++ Sbjct: 18 QTPMVQLHQL--FPKHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITENTHLIESTS 75 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV-------GELLDEAFE 118 GN G+A A A+ G+ T VV ++ +K+ GA V++V G L+ + Sbjct: 76 GNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAK 135 Query: 119 LAKALAKNNPGWVYIPPFDDPLIWEGHASIV-KELKETLWEKPGAIALSVGGGGLLCGVV 177 + + LA + + +I + + L W+ H E+ ET+ + V G + G+ Sbjct: 136 VQELLATIDDAY-WINQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMS 194 Query: 178 QGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQ 237 + ++EV + ++A++ G+ F +L +GA + Sbjct: 195 RKIKEVH-PNAQIVAVDAKGSVIFGDKPINREL---------------PGIGASRVPEIL 238 Query: 238 EHPIFSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPL 295 ++V + D ++ K +D E I + G+ +AA+ +I ++ + T L Sbjct: 239 NRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSIIAAI-EQLITSIEEGATIVTIL 297 Query: 296 PSLV 299 P Sbjct: 298 PDRG 301 >5XW3-A nrPDB Length = 315 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 72/315 (22%), Positives = 116/315 (36%), Gaps = 41/315 (13%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAG 66 TPI + S G ++ K++ P GS K R + ++G + +AG Sbjct: 14 TPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGLVTEGGTIIEPTAG 73 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKN 126 N G+ A AA Q + + VP E +K GATV V ++ + A+AK Sbjct: 74 NTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATV--VHTPTEQG--MTGAIAKA 129 Query: 127 NPGWVYIPPFDDPLIWEGH-------ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQG 179 IP P + ++ EL L + G GG G Sbjct: 130 KELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTGGTFMGTASY 189 Query: 180 LQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEH 239 L+E D+ + +E G+ GK A + + +G + + F + Sbjct: 190 LKEKNI-DIKTVIVEPEGS-----ILNGGK----------AGSHETEGIGLEFIPPFLKT 233 Query: 240 PIFSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 F E+ ISD+ A +++ E +LV + GAA A LE P + Sbjct: 234 SYFDEIHTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASL--------LEAEKAAPGTN 285 Query: 298 LVVIVCGGSNISLAQ 312 +V I S L++ Sbjct: 286 IVTIFPDSSERYLSK 300 >4COO-A nrPDB Length = 563 Score = 166 bits (421), Expect = 9e-42, Method: Composition-based stats. Identities = 56/303 (18%), Positives = 102/303 (33%), Gaps = 25/303 (8%) Query: 11 TPIRDSMALSKMAG--TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSS 64 TP+ + K G + K + GS K R + + G + + Sbjct: 109 TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 168 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAK- 121 +GN G+ A AA G IV+P + ++ L+ GA + D Sbjct: 169 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGV 228 Query: 122 --ALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQ 178 L P + + + H + E+ + K + SVG GG + G+ + Sbjct: 229 AWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIAR 288 Query: 179 GLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQE 238 L+E +I ++ G+ + L + V+ +G + + Sbjct: 289 KLKEK-CPGCRIIGVDPEGSILA-------EPEELNQTEQTT--YEVEGIGYDFIPTVLD 338 Query: 239 HPIFS--EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLP 296 + +D+EA + E +L + G+ +A V Q+LQ LP Sbjct: 339 RTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVA-VAVKAAQELQEGQRCVVILP 397 Query: 297 SLV 299 V Sbjct: 398 DSV 400 >1M54-A nrPDB Length = 363 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 56/303 (18%), Positives = 102/303 (33%), Gaps = 25/303 (8%) Query: 11 TPIRDSMALSKMAG--TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSS 64 TP+ + K G + K + GS K R + + G + + Sbjct: 44 TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 103 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAK- 121 +GN G+ A AA G IV+P + ++ L+ GA + D Sbjct: 104 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGV 163 Query: 122 --ALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQ 178 L P + + + H + E+ + K + SVG GG + G+ + Sbjct: 164 AWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIAR 223 Query: 179 GLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQE 238 L+E +I ++ G+ + L + V+ +G + + Sbjct: 224 KLKEK-CPGCRIIGVDPEGSILA-------EPEELNQTEQTT--YEVEGIGYDFIPTVLD 273 Query: 239 HPIFS--EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLP 296 + +D+EA + E +L + G+ +A V Q+LQ LP Sbjct: 274 RTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVA-VAVKAAQELQEGQRCVVILP 332 Query: 297 SLV 299 V Sbjct: 333 DSV 335 >5MMS-A nrPDB Length = 408 Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats. Identities = 56/303 (18%), Positives = 102/303 (33%), Gaps = 25/303 (8%) Query: 11 TPIRDSMALSKMAG--TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSS 64 TP+ + K G + K + GS K R + + G + + Sbjct: 87 TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 146 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAK- 121 +GN G+ A AA G IV+P + ++ L+ GA + D Sbjct: 147 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGV 206 Query: 122 --ALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQ 178 L P + + + H + E+ + K + SVG GG + G+ + Sbjct: 207 AWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIAR 266 Query: 179 GLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQE 238 L+E +I ++ G+ + L + V+ +G + + Sbjct: 267 KLKEK-CPGCRIIGVDPEGSILA-------EPEELNQTEQTT--YEVEGIGYDFIPTVLD 316 Query: 239 HPIFS--EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLP 296 + +D+EA + E +L + G+ +A V Q+LQ LP Sbjct: 317 RTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVA-VAVKAAQELQEGQRCVVILP 375 Query: 297 SLV 299 V Sbjct: 376 DSV 378 >5OHX-A nrPDB Length = 504 Score = 162 bits (409), Expect = 3e-40, Method: Composition-based stats. Identities = 58/304 (19%), Positives = 113/304 (37%), Gaps = 26/304 (8%) Query: 10 KTPIRDSMALSKMAG--TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCA----HFVCS 63 +TP+ + K G +Y K + P GS K R + +G + Sbjct: 45 QTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEP 104 Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL-----LDEAFE 118 ++GN G+ A AA G IV+P I L GA + + Sbjct: 105 TSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHIS 164 Query: 119 LAKALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVV 177 +A+ L K P + + + +P H E+ + K + G GG + G+ Sbjct: 165 VAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIG 224 Query: 178 QGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQ 237 + L+E+ ++ +IA++ G+ ++ + ++ V+ +G + Sbjct: 225 RKLKELS-PNIKIIAVDPKGSILDPSSDSQNEV----------GFYEVEGIGYDFIPTVL 273 Query: 238 EHPIFSEVI--SDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPL 295 + + + I D E++ A + E +L + GAAL + + + E + L Sbjct: 274 DRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAAL-IAALKIAKDIPEEKRMVIIL 332 Query: 296 PSLV 299 P + Sbjct: 333 PDGI 336 >6AHI-A nrPDB Length = 314 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 63/300 (21%), Positives = 111/300 (37%), Gaps = 28/300 (9%) Query: 10 KTPIRDSMALSKMAGTS--VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCS 63 +TP+ + +Y K++ P GS K R + K G + Sbjct: 13 RTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGKITSKTTIIEP 72 Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKV--VGELLDEAFELAK 121 +AGN G+A A A + + VVP + ++ GA V E + A + +K Sbjct: 73 TAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTSEGISGAIKKSK 132 Query: 122 ALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 LA++ P F++P + ++ E+ + L + +G GG G + L Sbjct: 133 ELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIGSGGTFAGTARYL 192 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQE-- 238 +E + +I +E G+ G+ ++ +G + + F E Sbjct: 193 KER-IPAIRLIGVEPEGS-----ILNGGEP----------GPHEIEGIGVEFIPPFFENL 236 Query: 239 HPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSL 298 E ISD+E + K +LV + GAA A Q+L + T P + Sbjct: 237 DIDGFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKE-AQRLPEGSQVLTIFPDV 295 >3FCA-A nrPDB Length = 291 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 68/300 (22%), Positives = 117/300 (39%), Gaps = 27/300 (9%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC--AHFVC 62 E L TPI ++ + LK++ P GS K R K+G V Sbjct: 3 ERLIGSTPIVRLDSIDS----RIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNGIVE 58 Query: 63 SSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELA 120 ++GN G+A A + G + +P T + LK GA + + + A E A Sbjct: 59 PTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGAVEKA 118 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQG 179 +++ G + F++P H + E+ + + + A VG GG + GV + Sbjct: 119 LEISRET-GAHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGVGRV 177 Query: 180 LQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEH 239 L+ V ++A+E + + G+ ++ +GA + + Sbjct: 178 LKGFFGNGVKIVAVEP----AKSPVLSGGQP----------GKHAIQGIGAGFVPKILDR 223 Query: 240 PIFSEVIS--DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 + EVI+ D+EA E +LV + GA +AA V QKL + + T P Sbjct: 224 SVIDEVITVEDEEAYEMARYLAKKEGLLVGISSGANVAAALK-VAQKLGPDARVVTVAPD 282 >6C2H-A nrPDB Length = 375 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 59/295 (20%), Positives = 105/295 (35%), Gaps = 30/295 (10%) Query: 7 LHVKTPIRDSMALSKMAGTS--VYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----- 59 L TP+ L K G +Y K++ P GS K R + G H Sbjct: 39 LVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHPSRST 98 Query: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKV--VGELLDEAF 117 + ++GN G+ A G I +P + LK GA + D Sbjct: 99 LIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPE 158 Query: 118 EL---AKALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPG-----AIALSVG 168 AK L K PG V + +++ + E H +E++ L + A+ G Sbjct: 159 SHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAG 218 Query: 169 GGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTV 228 GG + G+ + L+E + ++ + FG+ +L K V+ + Sbjct: 219 TGGTISGISKYLKEQN-DKIQIVGADPFGSILAQ-------PENLNKTDIT--DYKVEGI 268 Query: 229 GAQALKLFQEHPIFS--EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHV 281 G + + + D+ + + + +E +LV + G+A AV + Sbjct: 269 GYDFVPQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYC 323 >3PC3-A nrPDB Length = 527 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 56/304 (18%), Positives = 105/304 (34%), Gaps = 27/304 (8%) Query: 11 TPIRDSMAL--SKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCA----HFVCSS 64 TP+ + S +Y K + P GS K R + +QG + + Sbjct: 61 TPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPT 120 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKV--VGELLDEAFEL--- 119 +GN G+ A A G IV+P + L+ GA + D L Sbjct: 121 SGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYV 180 Query: 120 AKALAKNNPGWVYIPPFDDPLIWEGH--ASIVKELKETLWEKPGAIALSVGGGGLLCGVV 177 A+ L + P + + + + H + E+ L K I +S G G + G+ Sbjct: 181 AQQLQRETPNSIVLDQYRNAGNPLAHYDGTAA-EILWQLDNKVDMIVVSAGTAGTISGIG 239 Query: 178 QGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQ 237 + ++E ++ ++ +G+ + L K + V+ +G Sbjct: 240 RKIKE-QVPSCQIVGVDPYGSILA-------RPAELNKTDV--QFYEVEGIGYDFPPTVF 289 Query: 238 EHPIFSE--VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPL 295 + + I D + + +E +L + G A+ A H +KL+ L Sbjct: 290 DDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEH-ARKLKKGQRCVVIL 348 Query: 296 PSLV 299 P + Sbjct: 349 PDGI 352 >1J0B-A nrPDB Length = 325 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 70/277 (25%), Positives = 107/277 (38%), Gaps = 35/277 (12%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSA--QPSGSFKIRGIGHFCKRWAKQGCAHFVCSSA-- 65 +TPI+ +S+ G VY+K D G KIR + + +G + A Sbjct: 21 ETPIQYLPNISREIGADVYIKRDDLTGLGIGGNKIRKLEYLLGDALSKGADVVITVGAVH 80 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVG------------ELL 113 N AA++LG+ A +V+ E LK K++G EL+ Sbjct: 81 SNHAFVTGLAAKKLGLDAILVLRGK------EELKGNYLLDKIMGIETRVYDAKDSFELM 134 Query: 114 DEAFELAKALAKNNPGWVYIPPFD-DPLIWEGHASIVKELKETLWEKPGAIALSVGGGGL 172 A E+A+ L + IPP P+ G+ V E+ K +I ++ G GG Sbjct: 135 KYAEEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVGEIATQSEVKFDSIVVAAGSGGT 194 Query: 173 LCGVVQGLQEVGWGDVPV-IAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQ 231 L G+ GL + PV IA+ FG KL +L I A+ LGVK + Sbjct: 195 LAGLSLGLSILNEDIRPVGIAVGRFG------EVMTSKLDNL--IKEAAELLGVKV---E 243 Query: 232 ALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEP 268 ++ E I K E I+++P Sbjct: 244 VRPELYDYSFGEYGKITGEVAQIIRKVGTREGIILDP 280 >2JC3-A nrPDB Length = 303 Score = 146 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 56/311 (18%), Positives = 115/311 (36%), Gaps = 41/311 (13%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 TP+ + G+ +++K++ P+GS K R K+G + +++ Sbjct: 10 NTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATS 69 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKAL 123 GN G+A A A G +++P ++ GA + +V + ++ A +LA A+ Sbjct: 70 GNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALAM 129 Query: 124 AKNNPGWVYIPPFDDPLI-WEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 182 ++ G + F++P + + + E+ + S+G G + GV + L+E Sbjct: 130 SERGEG-KLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGTITGVSRFLRE 188 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 V ++ ++ S G++ A+ + + Sbjct: 189 QEKP-VTIVGLQPEEGSSIP---------------------GIRRWPAEYMPGIFNASLV 226 Query: 243 SEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 EV I +A + + E I + G A+A TP +V Sbjct: 227 DEVLDIHQNDAENTMRELAVREGIFCGVSSGGAVAGALR---------VARATPGAIVVA 277 Query: 301 IVCGGSNISLA 311 I+C + L+ Sbjct: 278 IICDRGDRYLS 288 >2BHS-A nrPDB Length = 303 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 58/320 (18%), Positives = 116/320 (36%), Gaps = 41/320 (12%) Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC--- 57 M + E TP+ + G+ V+LK++ P+GS K R K+G Sbjct: 1 MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP 60 Query: 58 -AHFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LD 114 + +++GN G+A A A G +++P ++ GA + +V + ++ Sbjct: 61 GDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGME 120 Query: 115 EAFELAKALAKNNPGWVYIPPFDDPLI-WEGHASIVKELKETLWEKPGAIALSVGGGGLL 173 A +LA +A G + F++P + + + E+ + + S+G G + Sbjct: 121 GARDLALEMANRGEG-KLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTI 179 Query: 174 CGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQAL 233 GV + ++E V ++ ++ S G++ + L Sbjct: 180 TGVSRFMREQSKP-VTIVGLQPEEGSSIP---------------------GIRRWPTEYL 217 Query: 234 KLFQEHPIFSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNL 291 + EV I ++A + + E I + G A+A Sbjct: 218 PGIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALR---------VAK 268 Query: 292 RTPLPSLVVIVCGGSNISLA 311 P +V I+C + L+ Sbjct: 269 ANPDAVVVAIICDRGDRYLS 288 >5YGR-A nrPDB Length = 404 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 62/351 (17%), Positives = 127/351 (36%), Gaps = 48/351 (13%) Query: 6 PLHVKTPIRDSMALSKMAG-TSVYLKMDSAQ-PSGSFKIRGIGHFCKRWAKQGCA----- 58 P + TP+ + LS+ G S+++K +S + +FK G + ++ Sbjct: 41 PNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGLGGSYAVGKYLADKLQCDINS 100 Query: 59 ------------------HFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLK 100 FV ++ GN G A+AA QLG+ A + +P + + E ++ Sbjct: 101 LSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIR 160 Query: 101 NEGATVKVVGELLDEAFELAKALAKNNPGWVYIPP-----FDDPLIW--EGHASIVKELK 153 + GA + D+A LA +A+ GWV + +++ W +G+ ++ E Sbjct: 161 HHGAECTITDLNYDDAVRLAHRMAQTK-GWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAY 219 Query: 154 ETLWEK----PGAIALSVGGGGLLCGVVQGLQEVGWGDVP-VIAMETFGAHSFHAATTAG 208 E L E P + L G G V+ E ++P +I +E A+ + + Sbjct: 220 EQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMD 279 Query: 209 KLVSLPKITSVAKALGVKTVGAQ---ALKLFQEHPIFSEVISDQEAVAAIEKFVD----D 261 +A + G + + +++ D A + Sbjct: 280 DGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGT 339 Query: 262 EKILVEPACGAALAAVYSHVIQKLQ---LEGNLRTPLPSLVVIVCGGSNIS 309 + + GA + ++ + L L+ + V+++ + S Sbjct: 340 DTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTS 390 >4OFX-A nrPDB Length = 319 Score = 144 bits (363), Expect = 6e-35, Method: Composition-based stats. Identities = 60/302 (19%), Positives = 114/302 (37%), Gaps = 28/302 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 KTP+ + + +Y K + P GS K R + KQG + ++ Sbjct: 15 KTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKIKPGDTLIEPTS 74 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATV--KVVGELLDEAFEL---A 120 GN G+ A A G I +P L+ GAT+ D+ A Sbjct: 75 GNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAAYDDPESHISLA 134 Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQG 179 K L + P + + + + H + +E+ + + E + + VG GG + GV + Sbjct: 135 KRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVVMGVGTGGTIIGVAKK 194 Query: 180 LQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEH 239 L+EV + +I ++ G+ LV + +G + ++ Sbjct: 195 LKEVN-PSIQIIGVDPIGSILGGGDEIKPYLV--------------EGIGYDFIPEVLDN 239 Query: 240 PIFSE--VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 + E I+D+++ + + +E +LV + G+A+ A Q+L+ LP Sbjct: 240 NLIDEYIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAA-CQAAQRLKEGERCLVILPD 298 Query: 298 LV 299 + Sbjct: 299 AI 300 >5I7O-A nrPDB Length = 326 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 63/282 (22%), Positives = 97/282 (34%), Gaps = 39/282 (13%) Query: 10 KTPIRDSMALSKMAG-------TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----A 58 TP+ LS ++ K++ P+GS K R ++ G A Sbjct: 16 NTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGA 75 Query: 59 HFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEA 116 + ++GN G++ A AAR G V+P T + L+ GA + + A Sbjct: 76 TILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTA 135 Query: 117 FELAKALAKNNPGWVYIPPFDDPLIWEGHASIVK-ELKETLWEKPGAIALSVGGGGLLCG 175 AK LA NP WV + + +P + H EL L E +G G L G Sbjct: 136 VATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPE-ITHFVAGLGTTGTLMG 194 Query: 176 VVQGLQEVGWGDVPVIAMETFGAHSFHA--ATTAGKLVSLPKITSVAKALGVKTVGAQAL 233 + L+E +V ++A E +A G + L + V V Sbjct: 195 TGRFLRE-HVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAV----- 248 Query: 234 KLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALA 275 +AV + V E I + GA L Sbjct: 249 ----------------DAVRRTRELVHTEGIFAGISTGAVLH 274 >5XEM-A nrPDB Length = 310 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 54/311 (17%), Positives = 101/311 (32%), Gaps = 26/311 (8%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 TP+ + G +Y+K++ + P S K R + K+G + +++ Sbjct: 16 NTPLVKINNID-TFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLIDKDTVIIEATS 74 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKAL 123 GN G+ A IV+P T I+ ++ G V + + E + L Sbjct: 75 GNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLGMKACLEKLEEL 134 Query: 124 AKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 182 KN + F + + H + +E+ + L K G GG G + L+E Sbjct: 135 KKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGGSFSGTAKKLKE 194 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 ++ +E + + G + G+ V +L Sbjct: 195 K-LPNIKTFPVEP----ASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDGSLA------DD 243 Query: 243 SEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIV 302 V D +A + + E IL + GA A + +VV+ Sbjct: 244 ILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDY-------SKENADKGLKIVVLS 296 Query: 303 CGGSNISLAQL 313 L+ + Sbjct: 297 TDSGEKYLSNI 307 >2EFY-A nrPDB Length = 304 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 59/299 (19%), Positives = 104/299 (34%), Gaps = 28/299 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC------AHFVCS 63 KTP+ + + V++K++ P GS K R + K ++G V Sbjct: 9 KTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPGSGQVIVEP 68 Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAK 121 ++GN G+ A A G + +P+ LK GA + + + A E A Sbjct: 69 TSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLAAREEAL 128 Query: 122 ALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180 L K G F +P H + EL E L + A G GG + GV + L Sbjct: 129 RL-KEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTITGVGRYL 187 Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240 +E V VIA+E ++ G + +G + + Sbjct: 188 KER-IPHVKVIAVEPARSNVLSGGKMGQH--------------GFQGMGPGFIPENLDLS 232 Query: 241 --IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 + +++A + +E + + + G + A V ++L + P Sbjct: 233 LLDGVIQVWEEDAFPLARRLAREEGLFLGMSSGGIVWAAL-QVARELGPGKRVACISPD 290 >4LMA-A nrPDB Length = 326 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 71/319 (22%), Positives = 124/319 (38%), Gaps = 34/319 (10%) Query: 7 LHVKTPIRDSMALSKMAGT--SVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC-----AH 59 L +TP+ + + G + +K++ P+ S K R H K G Sbjct: 17 LVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAGLINPETTV 76 Query: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAF 117 V ++GN G+A A A G + +P T LK GAT+++ + + A Sbjct: 77 LVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGSQGMKGAI 136 Query: 118 ELAKALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGV 176 A+ + + PG + F +P E H + +E+ + + I VG GG + GV Sbjct: 137 LRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGVGTGGTITGV 196 Query: 177 VQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLF 236 + ++ V+A+E F + + G ++ +GA + Sbjct: 197 AEVIKSRK-PSFQVVAVEPFNSPV----ISGGNP----------GPHKIQGIGAGFIPEV 241 Query: 237 QEHPIFSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTP 294 + EV +SD+EA + +E +L + GA L A + Q+ + EG L Sbjct: 242 LRTDLIDEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAI-QLAQRPENEGKL--- 297 Query: 295 LPSLVVIVCGGSNISLAQL 313 +VVI L+ L Sbjct: 298 ---IVVIQPSFGERYLSTL 313 >3VBE-A nrPDB Length = 344 Score = 137 bits (344), Expect = 8e-33, Method: Composition-based stats. Identities = 53/277 (19%), Positives = 101/277 (36%), Gaps = 21/277 (7%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQ-----GCAHFVCSS 64 +TP+ +++ G V +K + QP+ S K R ++ G + + Sbjct: 35 RTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKNLITPGKTTLIEPT 94 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKA 122 +GN G++ A+ A G + +PS T ++ GA + + + + A Sbjct: 95 SGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPAKGMGGTVKKAYE 154 Query: 123 LAKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 181 L +N P + F +P + H + E+ E + + +G GG + GV Q L+ Sbjct: 155 LLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIGSGGTVSGVGQYLK 214 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 +V + +E ++ GK VG + L + Sbjct: 215 SKN-PNVKIYGVEPSESNV----LNGGKPGPHHITG--------NGVGFKPDILDLDVME 261 Query: 242 FSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVY 278 +S ++AV E ++V + GA A Sbjct: 262 KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAAL 298 >5XA2-A nrPDB Length = 309 Score = 136 bits (343), Expect = 9e-33, Method: Composition-based stats. Identities = 67/297 (22%), Positives = 112/297 (37%), Gaps = 24/297 (8%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCA----HFVCSSA 65 +TP+ L+ + V K++ P+ S K R + G H V ++ Sbjct: 13 RTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGKLKPGMHVVEPTS 72 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAFELAKAL 123 GN G+A A+ G T+ +P T LK+ GA + + + + A A+ L Sbjct: 73 GNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGADGMKGAISKAEEL 132 Query: 124 AKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 182 A PGW F +P H + E+ + VG GG + GV + L+ Sbjct: 133 A-AQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTGGTITGVARFLKH 191 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 V V+A+E + AG A ++ +GA + + + Sbjct: 192 EKKHPVHVVAVEPAASP-----VLAGGP---------AGRHKIQGIGAGFVPDTFDRSVV 237 Query: 243 SEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 E+ ++D EA+ K +E I +CGAA+A + + T LP Sbjct: 238 DEILSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPD 294 >2Q3D-A nrPDB Length = 313 Score = 136 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 117/311 (37%), Gaps = 31/311 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSA 65 +TP+ ++ A + K++ P+ S K R + + G + ++ Sbjct: 16 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 75 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAFELAKAL 123 GN G+A A G + +P T L+ GA + + + + A A+ L Sbjct: 76 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 135 Query: 124 AKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 182 AK + + F++P H + +E+ K + VG GG + GV Q ++E Sbjct: 136 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKE 195 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 +A+E + + + +GA + + + Sbjct: 196 RK-PSARFVAVEPAASPVLSGGQKGPHPI--------------QGIGAGFVPPVLDQDLV 240 Query: 243 SEVIS--DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300 E+I+ +++A+ + +E +LV + GAA A V ++ + G L +VV Sbjct: 241 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAAL-QVARRPENAGKL------IVV 293 Query: 301 IVCGGSNISLA 311 ++ L+ Sbjct: 294 VLPDFGERYLS 304 >5J5V-A nrPDB Length = 323 Score = 133 bits (335), Expect = 8e-32, Method: Composition-based stats. Identities = 71/312 (22%), Positives = 134/312 (42%), Gaps = 29/312 (9%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66 TP+ L+++ + K++S PS S K R + K+G V ++G Sbjct: 15 TPLVR---LNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTSG 71 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKALA 124 N G+A AY A G T+ +P T + LK GA + + + A + A+ + Sbjct: 72 NTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIV 131 Query: 125 KNNP-GWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ- 181 +NP ++ + F +P E H + E+ E + VG GG L GV + ++ Sbjct: 132 ASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGTGGTLTGVSRYIKG 191 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 G D+ +A+E + A ++ P ++ +GA + + + Sbjct: 192 TKGKTDLISVAVEPTDSPVIAQALAGEEIKPGP--------HKIQGIGAGFIPANLDLKL 243 Query: 242 FSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLV 299 +V I+++EA++ + +++E IL + GAA+AA L+L+ + ++V Sbjct: 244 VDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAA-------LKLQEDESFTNKNIV 296 Query: 300 VIVCGGSNISLA 311 VI+ L+ Sbjct: 297 VILPSSGERYLS 308 >5B1I-A nrPDB Length = 311 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 52/271 (19%), Positives = 93/271 (34%), Gaps = 26/271 (9%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQG----CAHF 60 + L TP+ + + +Y K++ P GS R + + ++G Sbjct: 7 QELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRVNAKTTI 65 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAFE 118 + +AGN G+ A A + + +VVP ++ GA + E + A Sbjct: 66 IEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEGIKGAIR 125 Query: 119 LAKALAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVV 177 A+ALA F +P + ++ E+ + A G GG GV Sbjct: 126 KAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGGTFAGVA 185 Query: 178 QGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLF- 236 LQ + +E G + G A A + +G + + F Sbjct: 186 AYLQAQDSA-TKAVVVEPEG------SILNGGP---------AHAHRTEGIGVEFIPPFF 229 Query: 237 -QEHPIFSEVISDQEAVAAIEKFVDDEKILV 266 Q + I+D +A A + D +L+ Sbjct: 230 DQVRIDQTLTIADNDAFAQVRHLARDHGLLI 260 >4AEC-A nrPDB Length = 430 Score = 131 bits (328), Expect = 5e-31, Method: Composition-based stats. Identities = 56/272 (20%), Positives = 108/272 (39%), Gaps = 25/272 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQG-----CAHFVCSS 64 KTP+ +++K ++ K++ +P S K R ++G + V + Sbjct: 123 KTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPT 182 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKA 122 +GN G+ A+ A G + +P++ LK GA + + + A + A+ Sbjct: 183 SGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEE 242 Query: 123 LAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 181 + KN P + FD+P + H + E+ + K +G GG + GV + ++ Sbjct: 243 ILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIK 302 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 E VI +E + + GK ++ +GA + + I Sbjct: 303 EKNPK-TQVIGVEPTESD----ILSGGKP----------GPHKIQGIGAGFIPKNLDQKI 347 Query: 242 FSEV--ISDQEAVAAIEKFVDDEKILVEPACG 271 EV IS +EA+ ++ E ++V + G Sbjct: 348 MDEVIAISSEEAIETAKQLALKEGLMVGISSG 379 >1E5X-A nrPDB Length = 486 Score = 131 bits (328), Expect = 6e-31, Method: Composition-based stats. Identities = 51/306 (16%), Positives = 119/306 (38%), Gaps = 24/306 (7%) Query: 26 SVYLKMDSAQPSGSFKIRGIGHFCKRW--AKQGCAHFV---CSSAGNAGMAAAYAARQLG 80 +++K +GSFK G+ + ++ V C+S G+ A + G Sbjct: 148 DLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAG 207 Query: 81 VPATIVVP-STTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNPGWVYIPPFDDP 139 +P+ + +P + + + GA V + D +L + + P +Y+ + Sbjct: 208 IPSIVFLPANKISMAQLVQPIANGAFVLSIDTDFDGCMKLIREITAELP--IYLANSLNS 265 Query: 140 LIWEGHASIVKELKETL-WEKPGAIALSVGGGGLLCGVVQGLQEVGWGDV-----PVIAM 193 L EG + E+ + W+ P + + G G + +G + + ++ Sbjct: 266 LRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYKGFKMCQELGLVDRIPRMVCA 325 Query: 194 ETFGAHSFHAATTAG----KLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQ 249 + A+ + +G K ++ + A +G +A+ ++ E +++ Sbjct: 326 QAANANPLYLHYKSGWKDFKPMTASTTFASAIQIGDPVSIDRAVYALKKCNGIVEEATEE 385 Query: 250 EAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNIS 309 E + A+ + D + + P G AL A++ KL+ +G + ++VV G + Sbjct: 386 ELMDAMAQ-ADSTGMFICPHTGVALTALF-----KLRNQGVIAPTDRTVVVSTAHGLKFT 439 Query: 310 LAQLRA 315 +++ Sbjct: 440 QSKIDY 445 >2EGU-A nrPDB Length = 308 Score = 130 bits (326), Expect = 9e-31, Method: Composition-based stats. Identities = 64/310 (20%), Positives = 113/310 (36%), Gaps = 33/310 (10%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSAG 66 TP + VYLK++ P S K R + K G V ++G Sbjct: 15 TPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGKLKPGDTIVEPTSG 74 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKALA 124 N G+ A A G A +V+P T L+ GA + + + A A+ L Sbjct: 75 NTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGAQGMRGAIAKAEELV 134 Query: 125 KNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEV 183 + + G+ F + E H + KE+ E + ++ A VG GG + G + L+E Sbjct: 135 REH-GYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGTGGTITGAGKVLREA 193 Query: 184 GWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFS 243 + ++ + A+E + GK ++ +GA + + I+ Sbjct: 194 -YPNIKIYAVEPADSPVLS----GGKP----------GPHKIQGIGAGFVPDILDTSIYD 238 Query: 244 --EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 ++ +EA AA + +E IL + GAA+ A ++ I Sbjct: 239 GVITVTTEEAFAAARRAAREEGILGGISSGAAIHAALK--------VAKELGKGKKVLAI 290 Query: 302 VCGGSNISLA 311 + L+ Sbjct: 291 IPSNGERYLS 300 >2PQM-A nrPDB Length = 343 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 65/314 (20%), Positives = 116/314 (36%), Gaps = 35/314 (11%) Query: 11 TPIRDSMALSK----MAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVC 62 TP+ + +++ GT + +K++ P S K R + + K G + Sbjct: 24 TPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIE 83 Query: 63 SSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELA 120 S++GN G+A A G I +PST +K GA + + + A E Sbjct: 84 STSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEGKKGMPGAIEEV 143 Query: 121 KALAKNNPGWVYI-PPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQG 179 + K NPG ++ F +P H E+ E + + +VG G + GV + Sbjct: 144 NKMIKENPGKYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGVAEK 203 Query: 180 LQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEH 239 + + +IA+E + A GK G++ +GA + + Sbjct: 204 -LKEKKKGIKIIAVEPEES-----AVLEGK---------AKGPHGIQGIGAGFIPDIYKK 248 Query: 240 PIFSEVIS--DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 E+I Q+A V + I+ + GAA+ A L+ + Sbjct: 249 EFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILA-------GLKEAEKPENEGKT 301 Query: 298 LVVIVCGGSNISLA 311 +V+IV L+ Sbjct: 302 IVIIVPSCGERYLS 315 >4I1Y-A nrPDB Length = 314 Score = 127 bits (320), Expect = 5e-30, Method: Composition-based stats. Identities = 61/310 (19%), Positives = 112/310 (36%), Gaps = 31/310 (10%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66 TP+ ++ A V K++S P+GS K R K G + ++G Sbjct: 18 TPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGLIKPDTIILEPTSG 77 Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAFELAKALA 124 N G+A A + G + +P T L+ GA + + E + A A+ LA Sbjct: 78 NTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGAEGMAGAIAKAEELA 137 Query: 125 KNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEV 183 K + + F++P HA + +E+ K VG GG + GV Q +++ Sbjct: 138 KTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVGTGGTITGVAQVIKQR 197 Query: 184 GWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFS 243 +A+E + + + +GA + + + Sbjct: 198 R-PSAQFVAVEPAASPVLSGGQKGPHPI--------------QGIGAGFVPPVLDLALVD 242 Query: 244 EVIS--DQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVI 301 EVI+ + +A+ + +E +L + GAA+ A L +VV+ Sbjct: 243 EVITVGNDDALELARRMATEEGLLFGISSGAAVWAARE-------LAHRPENAGKLIVVV 295 Query: 302 VCGGSNISLA 311 + L+ Sbjct: 296 LPDFGERYLS 305 >4LMB-A nrPDB Length = 322 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 113/317 (35%), Gaps = 34/317 (10%) Query: 7 LHVKTPIRDSMALSKMAGT--SVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----- 59 L +TP+ + G + +K++S P+ S K R + G H Sbjct: 17 LVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTI 76 Query: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAF 117 V ++GN G+A A A G + +P T LK GA +++ + ++ A Sbjct: 77 LVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGSQGMEGAI 136 Query: 118 ELAKALAKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGV 176 A+ + +N P + F +P + H + +E+ + VG GG + G+ Sbjct: 137 TRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGGTITGI 196 Query: 177 VQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLF 236 + ++ IA+E + G+ ++ +GA + Sbjct: 197 AETIKPRR-PQFQAIAVEPSNSPVLS----GGQP----------GPHKIQGIGAGFIPAI 241 Query: 237 Q--EHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTP 294 E ++ D EA A + E +L + GAAL A +Q+ Sbjct: 242 FRPELIDEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAA-------IQVGKRPENE 294 Query: 295 LPSLVVIVCGGSNISLA 311 +V+I L+ Sbjct: 295 DKLIVMIQPSFGERYLS 311 >2ISQ-A nrPDB Length = 320 Score = 122 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 97/272 (35%), Gaps = 25/272 (9%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC-----AHFVCSS 64 TP+ +++ V K++ +P S K R K+G + + + Sbjct: 13 NTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPT 72 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKA 122 +GN G+ A+ A G I +P++ L G + + + A A+ Sbjct: 73 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 132 Query: 123 LAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 181 + P + F++P + H + E+ + K +G GG + G + L+ Sbjct: 133 ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLK 192 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 E +V + +E A + GK ++ +GA + + Sbjct: 193 EQN-ANVKLYGVEP----VESAILSGGKP----------GPHKIQGIGAGFIPSVLNVDL 237 Query: 242 FSEV--ISDQEAVAAIEKFVDDEKILVEPACG 271 EV +S E++ + E +LV + G Sbjct: 238 IDEVVQVSSDESIDMARQLALKEGLLVGISSG 269 >4D9G-A nrPDB Length = 398 Score = 120 bits (301), Expect = 7e-28, Method: Composition-based stats. Identities = 62/345 (17%), Positives = 126/345 (36%), Gaps = 40/345 (11%) Query: 11 TPIRDSMALSKMAGTS-VYLKMDSAQ-PSGSFKIRGIGHFCKRWAKQ------------- 55 TP+ L+ + G + +K +S + +FK+ G + + + Sbjct: 45 TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEH 104 Query: 56 ------GCAHFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV 109 F ++ GN G A+AA+QLG A I +P + ++ + N GA V Sbjct: 105 LKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVT 164 Query: 110 GELLDEAFELAKALAKNNPGWVYIPP-----FDDPLIW--EGHASIVKELKETLWEK--- 159 D+ L A+ + GW + + W +G+A++ E E + E Sbjct: 165 DMNYDDTVRLTMQHAQQH-GWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVT 223 Query: 160 PGAIALSVGGGGLLCGVVQGLQEVG-WGDVPVIAMETFGAHSFHAATTAGKLVSL-PKIT 217 P + L G G + GV+ L +V ++ I +E A + + G +V++ + Sbjct: 224 PTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMA 283 Query: 218 SVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKF----VDDEKILVEPACGAA 273 ++ L ++ + D A + +D +I+ + Sbjct: 284 TIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESGAVG 343 Query: 274 LA--AVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRAL 316 L A + Q+ L L ++V+++ + + R + Sbjct: 344 LGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREV 388 >3X43-A nrPDB Length = 332 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 55/279 (19%), Positives = 97/279 (34%), Gaps = 25/279 (8%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 +TPI ++ TSVY+K++S P GS K R +G V ++ Sbjct: 13 RTPIVRLQRMA-PEHTSVYVKVESFNPGGSVKDRLALSVVLDAEAKGLLKPGDTIVECTS 71 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVV--GELLDEAFELAKAL 123 GN G+A A A G V+ T + ++ G + + +A L Sbjct: 72 GNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLGSKGGNLIADEL 131 Query: 124 AKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 182 A+ GW FD+P H + E+ K ++ G V + Sbjct: 132 AEKY-GWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTTGTLTGVGQMLR 190 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 V +V V+A+E A A G+ ++ + + + + Sbjct: 191 VARPEVRVVALEPSNA----AMLARGEWSP----------HQIQGLAPNFVPGVLDRSVI 236 Query: 243 SEVISDQE--AVAAIEKFVDDEKILVEPACGAALAAVYS 279 ++++ E A + +E I + GA +A S Sbjct: 237 DDLVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALS 275 >3T4P-A nrPDB Length = 334 Score = 114 bits (284), Expect = 8e-26, Method: Composition-based stats. Identities = 61/298 (20%), Positives = 105/298 (35%), Gaps = 26/298 (8%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC-----AHFVCSS 64 +TP L+ V LKM+ P S K R + K+G + V SS Sbjct: 21 QTPALYLNKLNN-TKAKVVLKMECENPMASVKDRLGFAIYDKAEKEGKLIPGKSIVVESS 79 Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKA 122 +GN G++ A+ G I +P + L+ GA V + + A +AK Sbjct: 80 SGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILTPAALGMKGAVAMAKK 139 Query: 123 LAKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 181 + NP V F H + E+ E VG GG L GV + L+ Sbjct: 140 IVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVGTGGTLTGVARALK 199 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 ++G ++A+E + GK ++ +G + + + Sbjct: 200 KMG-SHARIVAVEPTESPVLS----GGKP----------GPHKIQGIGPGFVPDVLDRSL 244 Query: 242 FSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPS 297 EV ++ +A+ K + + + GA + A + + T +PS Sbjct: 245 IDEVLCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIPS 302 >5XCN-X nrPDB Length = 350 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 52/272 (19%), Positives = 102/272 (37%), Gaps = 20/272 (7%) Query: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSA 65 TP+ +V +K++ PS S K R + + K G V +++ Sbjct: 47 NTPLVRLKHFGH--NGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATS 104 Query: 66 GNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGEL--LDEAFELAKAL 123 GN G+A AY A G T+ +P T L G + + A A+ + Sbjct: 105 GNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGAKGAIAKAEEI 164 Query: 124 AKNNPG-WVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 181 ++P +V + F++P + H + E+ + K + VG GG + G+ + ++ Sbjct: 165 VASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIK 224 Query: 182 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 241 + +A+E + ++ P ++ +GA + + I Sbjct: 225 LDFGKQITSVAVEPVESPVISQTLAGEEVKPGP--------HKIQGIGAGFIPKNLDLSI 276 Query: 242 FS--EVISDQEAVAAIEKFVDDEKILVEPACG 271 E + A+A + + +E IL + G Sbjct: 277 IDRVETVDSDTALATARRLMAEEGILAGISSG 308 >5B55-A nrPDB Length = 340 Score = 107 bits (268), Expect = 6e-24, Method: Composition-based stats. Identities = 57/287 (19%), Positives = 107/287 (37%), Gaps = 28/287 (9%) Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHF 60 E L KTP+ + + K +++K +S +GS K R + K+ ++ A Sbjct: 14 ENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPI 73 Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVG---ELLDEAF 117 V +++GN G+A + LG P I +P +++ GA + +V + Sbjct: 74 VEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSI 133 Query: 118 ELAKALAKNNPGWVYIPPFDDPLIWEGHAS-IVKELKET---LWEKPGAIALSVGGGGLL 173 E K AKNNP F + E H I E+ L VG GG + Sbjct: 134 EKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTV 193 Query: 174 CGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQAL 233 G+ + ++E + + + +E + +L VAK ++ + + + Sbjct: 194 MGIGKRIKE-NFSNAKICPLEPLNS------------PTLSTGYKVAK-HRIEGISNEFI 239 Query: 234 K--LFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVY 278 + + + D +A+ +K + V + GA Sbjct: 240 PDLVKLDKLDNVVSVDDGDAIVMAQKLA-KCGLGVGISSGANFIGAL 285 >4D9F-A nrPDB Length = 342 Score = 99.1 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 59/314 (18%), Positives = 111/314 (35%), Gaps = 40/314 (12%) Query: 2 MSGEPLHV------------KTPIRDSMALSKMAGTSVYLKMDSAQP--SGSFKIRGIGH 47 M+ PLH TP+ LS G +Y+K D P G K+R + Sbjct: 12 MASMPLHHLTRFPRLEFIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLRKLEF 71 Query: 48 FCKRWAKQGCAHFVCSSA--GNAGMAAAYAARQLGVPATIVV--PSTTPAL------TIE 97 ++G + + A N A A +LG+ ++ P T A Sbjct: 72 LVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRL 131 Query: 98 RLKNEGATVKVVGELLD---EAFELAKALAKNNPGWVYIPPFD-DPLIWEGHASIVKELK 153 L +++ L D + LA + IP L G+ E+ Sbjct: 132 LLDLFNTQIEMCDALTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIA 191 Query: 154 ETLWEKPG--AIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLV 211 + E G ++ ++ G G G+ GL+ + DV +I + + + K Sbjct: 192 QQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLM-PDVELIGV------TVSRSVAEQKPK 244 Query: 212 SLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPA-C 270 + ++A L + + L+ ++ + + + A++ E +L++P Sbjct: 245 VIALQQAIAGQLALTATAD--IHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYT 302 Query: 271 GAALAAVYSHVIQK 284 G A+A + + QK Sbjct: 303 GKAMAGLIDGISQK 316 >3VSD-A nrPDB Length = 389 Score = 91.7 bits (226), Expect = 4e-19, Method: Composition-based stats. Identities = 47/269 (17%), Positives = 93/269 (34%), Gaps = 30/269 (11%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQP-SGSFKIRGIGHFCKRWAKQGCAH--FVCSSAGN 67 TP+ S L G V+LK++ P S S R R +++ +++ N Sbjct: 97 TPLVRS-RLQLPNGVRVWLKLEWYNPFSLSVADRPAVEIISRLSRRVEKGSLVADATSSN 155 Query: 68 AGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA-KN 126 G+A + AR G A + +P + GA V V E L + + Sbjct: 156 FGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAPSTVHLLPRVMKDSK 215 Query: 127 NPGWVYIPPFDDPLIWEGHAS-IVKELKETLWE---KPGAIALSVGGGGLLCGVVQGLQE 182 N G+V++ F + +E H +E+ +A S+G G + LQ Sbjct: 216 NEGFVHVNQFYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAAAFYLQS 275 Query: 183 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 242 V + + ++ S + + + + Sbjct: 276 VD-PSIRAVLVQPAQGDS----------------IPGIRRVETGMLWIN----MLDISYT 314 Query: 243 SEVISDQEAVAAIEKFVDDEKILVEPACG 271 ++ +EA+ A+ + + +++ P+ G Sbjct: 315 LAEVTLEEAMEAVVEVARSDGLVIGPSGG 343 >5EY5-B nrPDB Length = 399 Score = 91.4 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 66/305 (21%), Positives = 110/305 (36%), Gaps = 42/305 (13%) Query: 11 TPIRDSMALSKMAG-TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNA 68 TP+ + L+K G +YLK + +G+ KI + G + + AG Sbjct: 51 TPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKRVIAETGAGQH 110 Query: 69 GMAAAYAARQLGVPATIVV---PSTTPALTIERLKNEGATVKVV---GELLDEAFELAKA 122 G+A A A G+ + + AL + R+K GA V+ V L +A A Sbjct: 111 GVATATVAAMFGLECVVYMGAEDIERQALNVFRMKLLGAKVRPVTSGSRTLKDAINEAMR 170 Query: 123 --LAKNNPGWVYIPPFDDPL-----IWEGHASIVKELKETLWEK----PGAIALSVGGGG 171 + + I P + + + I +E ++ + EK P AI VGGG Sbjct: 171 DWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEARQQILEKEGRLPDAIVACVGGGS 230 Query: 172 LLCGVVQGLQEVGWGDVPVIAMETFGAHSF----HAATTAGKLVSLP------------- 214 G+ + V +I +E G A +AG+ L Sbjct: 231 NAMGIFHPF--IDDESVRLIGVEAAGKGIETGKHAATLSAGRPGVLHGAMTYLLQDEDGQ 288 Query: 215 --KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKIL--VEPAC 270 + S++ L VG + L ++D EA+ A + E I+ +E + Sbjct: 289 IIEAHSISAGLDYPGVGPEHAYLKDTGRAEYVSVTDDEALEAFQLLSRTEGIIPALESSH 348 Query: 271 GAALA 275 A A Sbjct: 349 AVAYA 353 >5OCW-B nrPDB Length = 442 Score = 89.8 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 63/312 (20%), Positives = 107/312 (34%), Gaps = 50/312 (16%) Query: 11 TPIRDSMALSKMAG-TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNA 68 +P+ ++ LS+ AG ++LK + +GS KI + + G + + AG Sbjct: 102 SPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTRVIAETGAGQH 161 Query: 69 GMAAAYAARQLGVPATIVV---PSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 125 G+A A A LG+ I + + AL + R++ GA V V + L A+ + Sbjct: 162 GVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAEVVAVQ---TGSKTLKDAINE 218 Query: 126 NNPGWVYIPPFDDPL---------------IWEGHASIVKE----LKETLWEKPGAIALS 166 WV D+ + + I E ++ P A+ Sbjct: 219 AFRDWVA--NADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVAC 276 Query: 167 VGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSF----HAATTAGKLVSLP-------- 214 VGGG G+ + V ++ E G A TAG + Sbjct: 277 VGGGSNAIGIFHAF--LDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLLQ 334 Query: 215 -------KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVE 267 + S++ L VG + L + + I+D EA+ A E I+ Sbjct: 335 DEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIPA 394 Query: 268 PACGAALAAVYS 279 A+A Sbjct: 395 IESAHAVAGALK 406 >5KIN-B nrPDB Length = 407 Score = 89.0 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 67/351 (19%), Positives = 118/351 (33%), Gaps = 63/351 (17%) Query: 10 KTPIRDSMALSKMAG-TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGN 67 +TP+ + L++ G +YLK + +G+ KI + G + + AG Sbjct: 59 ETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQ 118 Query: 68 AGMAAAYAARQLGVPATIVVPS---TTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124 G+A A AA + TI + AL + R++ GA V+ V + + K A Sbjct: 119 HGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAV----TDGSRVLKD-A 173 Query: 125 KNNPGWVYIPPFDDPLIWEG---------------HASIVKELKETL-----WEKPGAIA 164 N ++ DD G + I +E K+ + P A+ Sbjct: 174 VNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGRDLPDALV 233 Query: 165 LSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFG----AHSFHAATTAGKLVSLP------ 214 VGGG G+ E V + E G A T G+ L Sbjct: 234 ACVGGGSNAIGLFHPFVE--DESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDV 291 Query: 215 ---------KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKIL 265 + S++ L +G + ++D+EA+ + E I+ Sbjct: 292 LQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGII 351 Query: 266 --VEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLR 314 +E + A A P S++V + G + + Q++ Sbjct: 352 PALESSHAIAFAVKL----------AKELGPEKSMIVCLSGRGDKDVVQVK 392 >1X1Q-A nrPDB Length = 418 Score = 84.0 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 64/306 (20%), Positives = 107/306 (34%), Gaps = 40/306 (13%) Query: 11 TPIRDSMALSKM-AGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNA 68 TP+ + LS+ G V+LK + +G+ KI + G + + AG Sbjct: 78 TPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETGAGQH 137 Query: 69 GMAAAYAARQLGVPATIVVPSTTP---ALTIERLKNEGATVKVV---GELLDEAFELAKA 122 G++ A A G+ + + AL + R+K GA V+ V L +A A Sbjct: 138 GVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEAIR 197 Query: 123 --LAKNNPGWVYIPPFDDPL-----IWEGHASIVKELKETL----WEKPGAIALSVGGGG 171 + + + P + + + I +E+K P A+ +VGGG Sbjct: 198 DWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFGRLPDALIAAVGGGS 257 Query: 172 LLCGVVQGLQEVGWGDVPVIAMETFGAHSF----HAATTAGKLVSLP------------- 214 G+ + G +I +E G A+ AGK L Sbjct: 258 NAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKRGVLHGSYMYLLYDHDGQ 317 Query: 215 --KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKIL--VEPAC 270 SV+ L VG + ++D+EA+ + E I+ +E A Sbjct: 318 ITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFKLLARLEGIIPALESAH 377 Query: 271 GAALAA 276 A AA Sbjct: 378 AIAYAA 383 >3SS9-X nrPDB Length = 442 Score = 83.7 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 62/341 (18%), Positives = 112/341 (32%), Gaps = 45/341 (13%) Query: 21 KMAGTSVYLKMDSAQP-SGSFKIRG-----IGHFCKRWAKQGCAH--------------- 59 + + LK DS P SGS K RG + H K + G Sbjct: 97 QPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQ 156 Query: 60 ------FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELL 113 S GN G++ + ++G T+ + + A +L++ G TV + Sbjct: 157 FFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDY 216 Query: 114 DEAFELAKALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEK--------PGAIAL 165 A E + A+++P +I + ++ G++ + LK ++ P + L Sbjct: 217 GVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL 276 Query: 166 SVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLP------KITSV 219 G GG GV GL+ V E + G + + Sbjct: 277 PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTA 336 Query: 220 AKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAA--- 276 A L V + + +SDQ + +E I +EP+ A +A Sbjct: 337 ADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQR 396 Query: 277 -VYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRAL 316 S Q++ + + +V GG + ++ Sbjct: 397 VCASVSYQQMHGFSAEQLRNTTHLVWATGGGMVPEEEMNQY 437 >6AMI-A nrPDB Length = 396 Score = 83.7 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 65/305 (21%), Positives = 105/305 (34%), Gaps = 42/305 (13%) Query: 11 TPIRDSMALSKMAG-TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNA 68 TP+ + L++ G VYLK + G+ K G + + AG Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQH 110 Query: 69 GMAAAYAARQLGVPATIVV---PSTTPALTIERLKNEGATVKVVG---ELLDEAFELAKA 122 G+A A A LG+ I + + + R+K GA V V L +A A Sbjct: 111 GVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALR 170 Query: 123 --LAKNNPGWVYIPPFDDPL-----IWEGHASIVKELKETL----WEKPGAIALSVGGGG 171 +A I P + + + I +E K + + P I VGGG Sbjct: 171 DWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGS 230 Query: 172 LLCGVVQGLQEVGWGDVPVIAMETFGAHSFH----AATTAGKLV---------------S 212 G+ V V ++ +E G A+ AG++ Sbjct: 231 NAMGI--FYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQ 288 Query: 213 LPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKIL--VEPAC 270 + S+A L VG + L + ++D+EA+ A + E I+ +E A Sbjct: 289 IKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAH 348 Query: 271 GAALA 275 A A Sbjct: 349 AVAYA 353 >1RQX-A nrPDB Length = 338 Score = 82.1 bits (201), Expect = 3e-16, Method: Composition-based stats. Identities = 61/307 (19%), Positives = 103/307 (33%), Gaps = 34/307 (11%) Query: 11 TPIRDSMALSKMAGTSV--YLKMDSAQPS---GSFKIRGIGHFCKRWAKQGCAHFVCSSA 65 TPI+ LSK G V Y K + G K R + + QGC V Sbjct: 16 TPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIPEALAQGCDTLVSIGG 75 Query: 66 --GNAGMAAAYAARQLGVPATIVVPS--TTPALTIERL------KNEGATVKVVGELLDE 115 N A A LG+ +V + +R+ + GA V++V + D Sbjct: 76 IQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVRLVPDGFDI 135 Query: 116 AFELA-----KALAKNNPGWVYIPP--FDDPLIWEGHASIVKELKET---LWEKPGAIAL 165 F + +++ IP D PL G +E++ L K + + Sbjct: 136 GFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAELGFKFDYVVV 195 Query: 166 SVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGV 225 G G+V G G D VI ++ + A+ +G+ Sbjct: 196 CSVTGSTQAGMVVGFAADGRAD-RVIGVDASAKPAQTREQITR------IARQTAEKVGL 248 Query: 226 KTVGAQALKLFQEHPIFSEV-ISDQEAVAAIEKFVDDEKILVEPA-CGAALAAVYSHVIQ 283 + +A + E E + ++ + AI E +L +P G ++ + V Sbjct: 249 ERDIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEGKSMHGMIEMVRN 308 Query: 284 KLQLEGN 290 EG+ Sbjct: 309 GEFPEGS 315 >5KZM-B nrPDB Length = 396 Score = 80.2 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 67/351 (19%), Positives = 117/351 (33%), Gaps = 52/351 (14%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNAG 69 T + + + K T +YLK + G+ K + + G + + AG G Sbjct: 56 TALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHG 115 Query: 70 MAAAYAARQLGVPATIVVPSTTPAL---TIERLKNEGATVKVVG----ELLDEAFELAKA 122 +A A A L + + + + + R+K GA V V L D E + Sbjct: 116 VATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRD 175 Query: 123 LAKNNPGWVYI-------PPFDDPLIWEGHASIVKELKETL----WEKPGAIALSVGGGG 171 + N Y+ PF ++ E I +E K+ + P A+ VGGG Sbjct: 176 WSANYSKAHYLLGTAAGPHPFP-TIVREFQRMIGEETKQQMLAKEGRLPDAVIACVGGGS 234 Query: 172 LLCGVVQGLQEVGWGDVPVIAMETFGAH-------------------SFHAATTAGKLVS 212 G+ + +V +I +E G A Sbjct: 235 NAIGMFADF--IDEKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQ 292 Query: 213 LPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKIL--VEPAC 270 + + S++ L +VG Q L +D EA+ A + E I+ +E + Sbjct: 293 IEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKEGIIPALESSH 352 Query: 271 GAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQLG 321 A A L+L LVV + G + + + + ++ G Sbjct: 353 ALAHA---------LKLAYEDPNKEQLLVVNLSGRGDKDIFTVHDILKEKG 394 >4NEG-A nrPDB Length = 400 Score = 77.9 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 68/354 (19%), Positives = 118/354 (33%), Gaps = 58/354 (16%) Query: 10 KTPIRDSMALSKMAG-TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGN 67 +TP+ + +++ G +YLK + +G+ KI + G V + AG Sbjct: 62 ETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQ 121 Query: 68 AGMAAAYAARQLGVPATIVVPSTTP---ALTIERLKNEGATVKVVGELLDEAFELAKALA 124 G+A A LG+ I + L + R++ GA V+ V A A Sbjct: 122 HGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVA-----AGSGTLKDA 176 Query: 125 KNNPGWVYIPPFDDPLIWEG---------------HASIVKELKETL----WEKPGAIAL 165 N ++ D G + I E K+ + P A+ Sbjct: 177 VNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVA 236 Query: 166 SVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGA----HSFHAATTAGKLVSLP------- 214 +GGG G+ V +V + +E G A T G + L Sbjct: 237 CIGGGSNAMGM--FYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLL 294 Query: 215 --------KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILV 266 + S++ L VG + L + I+D EA+ A + E I+ Sbjct: 295 QNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIP 354 Query: 267 EPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQL 320 A+A Q + EG LV+ + G + + ++ E++ Sbjct: 355 ALESSHAVAYALKLAPQMKEDEG--------LVICLSGRGDKDVESIKRYMEEV 400 >6HUL-B nrPDB Length = 425 Score = 77.5 bits (189), Expect = 7e-15, Method: Composition-based stats. Identities = 65/352 (18%), Positives = 118/352 (33%), Gaps = 48/352 (13%) Query: 11 TPIRDSMALSKMAG--TSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS-AGN 67 TP+ + L + +Y K + A P+GS KI ++G H V + AG Sbjct: 76 TPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAKEEGIEHVVTETGAGQ 135 Query: 68 AGMAAAYAARQLGVPATIVVPSTT---PALTIERLKNEGATVKVVGELLDEAFELAKALA 124 G A A AA + +TI + + + ++ GA V L E Sbjct: 136 WGTAVALAASMYNMKSTIFMVKVSYEQKPMRRSIMQLYGANVYASPTNLTEYGRKILETN 195 Query: 125 KNNPG-----------------WVYIPPFDDPLIWEGHASIVKELKET---LWEKPGAIA 164 +PG + Y+ ++ + I +E L E + Sbjct: 196 PQHPGSLGIAMSEAIEYALKNEFRYLVGSVLDVVLLHQSVIGQETITQLDLLGEDADILI 255 Query: 165 LSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSF------HAATTAGKLVSLPKITS 218 VGGG G IA+ + F + + L+ L K+ + Sbjct: 256 GCVGGGSNFGGFTYPF-IGNKKGKRYIAVSSAEIPKFSKGEYKYDFPDSAGLLPLVKMIT 314 Query: 219 VAKALGVKTVGAQALKLFQEHPIFSEVI----------SDQEAVAAIEKFVDDEKILVEP 268 + K + A L+ P S + +++E A + F++++ I+ P Sbjct: 315 LGKDYVPPPIYAGGLRYHGVAPTLSLLTKEGIVEWREYNEREIFEAAKIFIENQGIVPAP 374 Query: 269 ACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQL 320 A+ AV I E +V + G + L+ ++ ++L Sbjct: 375 ESAHAIRAVVDEAI-----EARKNNERKVIVFNLSGHGLLDLSNYESMMKRL 421 >3R0X-A nrPDB Length = 448 Score = 76.0 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 59/337 (17%), Positives = 107/337 (31%), Gaps = 44/337 (13%) Query: 24 GTSVYLKMDSAQPSGSFKIRG-----IGHFCKRWAKQGCAH------------------- 59 G + K SGS K RG + H K + G Sbjct: 99 GEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQ 158 Query: 60 --FVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAF 117 S GN G++ + +G T+ + + A +L++ G TV + A Sbjct: 159 YSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAV 218 Query: 118 ELAKALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEK--------PGAIALSVGG 169 E + A+++P +I + ++ G+A + LK ++ P + L G Sbjct: 219 EQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGV 278 Query: 170 GGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLP------KITSVAKAL 223 GG GV GL+ +V E + G ++ + A L Sbjct: 279 GGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGL 338 Query: 224 GVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAA----VYS 279 V + + + DQ + +E I +EP+ A +A S Sbjct: 339 AVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAS 398 Query: 280 HVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRAL 316 Q+ + + +V GG + ++ Sbjct: 399 VAYQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQY 435 >1CX9-B nrPDB Length = 397 Score = 72.1 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 65/348 (18%), Positives = 122/348 (35%), Gaps = 46/348 (13%) Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFV-CSSAGNAG 69 T + ++ T++YLK + G+ K + + G + + + AG G Sbjct: 57 TALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHG 116 Query: 70 MAAAYAARQLGVPATIVVPSTTPAL---TIERLKNEGATVKVVGELLDEAFELAKALAKN 126 +A+A A+ LG+ I + + + R++ GA V V + ++ Sbjct: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176 Query: 127 NPGWVYIPPF-------DDPL---IWEGHASIVKELKETLWEK----PGAIALSVGGGGL 172 G + P + E I +E K + +K P A+ VGGG Sbjct: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSN 236 Query: 173 LCGVVQGLQEVGWGDVPVIAMETFGAHSF----HAATTAGKL---------------VSL 213 G+ + V +I +E G A G++ + Sbjct: 237 AIGMFADF--INDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQI 294 Query: 214 PKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAA 273 + S++ L +VG Q L I+D EA+ A + E I+ PA ++ Sbjct: 295 EESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGII--PALESS 352 Query: 274 LAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQLG 321 A ++ + + Q E LVV + G + + + + + G Sbjct: 353 HALAHALKMMREQPEK-----EQLLVVNLSGRGDKDIFTVHDILKARG 395 >6EQN-B nrPDB Length = 425 Score = 64.4 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 63/348 (18%), Positives = 105/348 (30%), Gaps = 55/348 (15%) Query: 11 TPIRDSMALSKMAGTSV--YLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS-AGN 67 TPI + L + G ++ YLKM+S +GS KI + AG Sbjct: 76 TPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYYAKLDNAKFVTTETGAGQ 135 Query: 68 AGMAAAYAARQLGVPATIVVPST---TPALTIERLKNEGATVKVVGELLDE--------- 115 G + A A+ + A I + T ++ GA V L E Sbjct: 136 WGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAEVHPSPSDLTEFGRQLLAKD 195 Query: 116 ---------AFELAKALAKNNPGWVYIPPFDDPLI----WEGHASIVKELKETLWEKPGA 162 A A A N G + + I G K+ E + E P Sbjct: 196 SNHPGSLGIAISDAVEYAHKNGGKYVVGSVVNSDIMFKTIAGME--AKKQMELIGEDPDY 253 Query: 163 IALSVGGGGLLCGVV----------QGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVS 212 I VGGG + ++ + + KL+ Sbjct: 254 IIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIASGSSEVPKMTKGVYKYDYPDTAKLLP 313 Query: 213 LPKITSVAKALGVKTVGAQALKLFQEHPIFSEVI----------SDQEAVAAIEKFVDDE 262 + K+ ++ V A L+ P S +I S +E+ + F + E Sbjct: 314 MLKMYTIGSDFVPPPVYAGGLRYHGVAPTLSLLISKGIVQARDYSQEESFKWAKLFSELE 373 Query: 263 KILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISL 310 + P AL ++ ++ E +++V G + L Sbjct: 374 GYIPAPETSHAL-----PILAEIAEEAKKSGERKTVLVSFSGHGLLDL 416 >1VB3-A nrPDB Length = 428 Score = 57.5 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 39/264 (14%), Positives = 73/264 (27%), Gaps = 18/264 (6%) Query: 36 PSGSFKI---RGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQL-GVPATIVVPSTT 91 P+ +FK R + A + +++G+ G A A+A L V I+ P Sbjct: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 Query: 92 -PALTIERLKNEGATV--KVVGELLDEAFELAKALAKNNPGWVYI----PPFDDPLIWEG 144 L + G + + D L K + V + + Sbjct: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 Query: 145 HASIVKELKETLWEKP-GAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHA 203 E L ++ + +SV G L + V T + Sbjct: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPR 281 Query: 204 ATTAGK--LVSLPKITSVAKALGVKTVGAQALKLFQ----EHPIFSEVISDQEAVAAIEK 257 G+ + S A + + +LF+ + D E + Sbjct: 282 FLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMR 341 Query: 258 FVDDEKILVEPACGAALAAVYSHV 281 + + EP A A+ + Sbjct: 342 ELKELGYTSEPHAAVAYRALRDQL 365 >4PET-A nrPDB Length = 357 Score = 31.7 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 25/71 (35%) Query: 145 HASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAA 204 + EL + ++++ G ++ G G G + D+ + M G A Sbjct: 125 YYGGGMELMKKVYDQYGIMSFPGGNTGNQMGGWFKKEINSVEDLKGLKMRIPGFAGEVLA 184 Query: 205 TTAGKLVSLPK 215 K ++P Sbjct: 185 KLGAKPTNIPS 195 >2HQ1-A nrPDB Length = 247 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 32/198 (16%), Positives = 67/198 (33%), Gaps = 7/198 (3%) Query: 55 QGCAHFVCSSAGNAGMAAAYAARQLGVPATIVV---PSTTP-ALTIERLKNEGATVKVVG 110 +G V S+ G A A+ + + A IV+ P++T T E K G V V Sbjct: 4 KGKTAIVTGSSRGLGKAIAW--KLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAK 61 Query: 111 ELLDEAFELAKALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGG 170 + ++ + + I + +++ ++ E W+ L Sbjct: 62 GDVKNPEDVENMVKTAMDAFGRIDILVNNAGIT-RDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 171 GLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGA 230 L++ + + ++ ++ A A K + S+AK K + Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC 180 Query: 231 QALKLFQEHPIFSEVISD 248 A+ ++V+ D Sbjct: 181 NAVAPGIIKTDMTDVLPD 198 >6EKH-Y nrPDB Length = 123 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 39/102 (38%), Gaps = 4/102 (3%) Query: 45 IGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQLG--VPATIVVPSTTPALTIERLKNE 102 + + KR + V A N A A + IV+P T + +K + Sbjct: 16 MRNILKRILSTTNKYVVIGEAANGADAIKMAEELQPDLISMDIVMPETDGITATKAIKEK 75 Query: 103 GATV-KVVGELLDEAFELAKALAKNNPGWVYIPPFDDPLIWE 143 + V+ +D+ ++ A+ G++ + PF P I E Sbjct: 76 TPEIKIVMCTSVDQEQKMIDAVNAGADGYI-VKPFQAPKILE 116 >2VCY-A nrPDB Length = 344 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 24/66 (36%), Gaps = 1/66 (1%) Query: 51 RWAKQGCAHFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTI-ERLKNEGATVKVV 109 + G + +S G A A LG+ VV + +RLK+ GA + Sbjct: 150 EQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVIT 209 Query: 110 GELLDE 115 E L Sbjct: 210 EEELRR 215 >1F8F-A nrPDB Length = 371 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 2/83 (2%) Query: 32 DSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQLGVPATIVVPSTT 91 + P G G G + FV AG G++A AA+ G A+I++ Sbjct: 166 ELLGPLGCGIQTGAGACINALKVTPASSFVTWGAGAVGLSALLAAKVCG--ASIIIAVDI 223 Query: 92 PALTIERLKNEGATVKVVGELLD 114 +E K GAT + + D Sbjct: 224 VESRLELAKQLGATHVINSKTQD 246 >3ZRR-A nrPDB Length = 384 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 30/83 (36%), Gaps = 5/83 (6%) Query: 116 AFELAKALAKNNPGWVYI---PPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGL 172 + E +ALA + G Y+ PLI G + E +L + I V G+ Sbjct: 30 SKEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGTSAMESVTSLLKPNDKIL--VVSNGV 87 Query: 173 LCGVVQGLQEVGWGDVPVIAMET 195 + + + +V V+ Sbjct: 88 FGDRWEQIFKRYPVNVKVLRPSP 110 >2G2R-H nrPDB Length = 219 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 32/102 (31%), Gaps = 2/102 (1%) Query: 103 GATVKVVGELLDEAFELAKALAKNNPGWVYIPPFDDPL--IWEGHASIVKELKETLWEKP 160 G V + + A+ +L + Y P+D ++ GH ++V Sbjct: 66 GKATLTVDKSSNTAYMDLNSLTSEDSAVYYCVPYDYAADRVYWGHGTLVTVSTAKTTAPS 125 Query: 161 GAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFH 202 V GG V G G+ PV G+ S Sbjct: 126 VYPLAPVCGGTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSG 167 >5CM6-A nrPDB Length = 358 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 24/73 (32%) Query: 145 HASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAA 204 + EL + +++ G ++ G G+ G + D+ + M G A Sbjct: 125 YYGGGMELMKETYDQYGILSFPGGNTGVQMGGWFRKEINTVEDLKGLKMRIPGFAGEVLA 184 Query: 205 TTAGKLVSLPKIT 217 ++P Sbjct: 185 KLGASPTNIPSAE 197 >1JWB-B nrPDB Length = 249 Score = 28.2 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 38/98 (38%), Gaps = 3/98 (3%) Query: 161 GAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFG-AHSFHAATTAGKLVSLPKITSV 219 + L VG GGL C Q L G G++ ++ +T ++ + V PK+ S Sbjct: 31 DSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESA 90 Query: 220 AKAL--GVKTVGAQALKLFQEHPIFSEVISDQEAVAAI 255 AL + + + + +I++ + V Sbjct: 91 RDALTRINPHIAITPVNALLDDAELAALIAEHDLVLDC 128 >6OMZ-A nrPDB Length = 293 Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 49/170 (28%), Gaps = 39/170 (22%) Query: 35 QPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQL--------------- 79 QP ++ G+ + + G A G+A A Q+ Sbjct: 17 QPGTPVQVMGVVNVTQDSFSDGGKFIDTDRAVEHGLALVAAGAQIIDVGGESTRPGATRI 76 Query: 80 --GVPATIVVP--------------STTPALTIERLKNEGATVK--VVGELLDEAFELAK 121 GV A V P T A GA + V G D +A Sbjct: 77 DPGVEAARVTPVIRELAAQGITISIDTMHADVARAALEAGAHIVNDVSGGRADPG--MAG 134 Query: 122 ALAKNNPGWVYIP----PFDDPLIWEGHASIVKELKETLWEKPGAIALSV 167 LA+ W+ + D P G+ +V E++ L A + Sbjct: 135 VLAEAKVPWILMHWRSVDADHPHRVPGYRDVVAEVRTELLAAVDAAVTAG 184 >3DAH-A nrPDB Length = 319 Score = 27.8 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 3/65 (4%) Query: 167 VGGGGLLCGVVQGLQEVGWGDVPVIAMETF---GAHSFHAATTAGKLVSLPKITSVAKAL 223 V G LC Q L+E G V A GA AA+ +LV I A++L Sbjct: 226 VDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESL 285 Query: 224 GVKTV 228 + Sbjct: 286 ACPKI 290 >2PNF-A nrPDB Length = 248 Score = 27.8 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 37 SGSFKIRGIGHFC-KRWAKQGCAHFVCSSAGNAGMAAA-YAARQLGVPATIV 86 +GS RGIG ++ A G + ++G A A A + GV A V Sbjct: 13 TGS--TRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 >4EVZ-A nrPDB Length = 258 Score = 27.4 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 23/59 (38%), Gaps = 3/59 (5%) Query: 115 EAFELAKALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLL 173 +A E A+ + + G + + D G+ EL + E ++ GG G L Sbjct: 152 DAVEWARKVVELGAGEILLTSMDRDGTKAGYD---LELTRAVSEAVSVPVIASGGAGEL 207 >5TNX-A nrPDB Length = 383 Score = 27.4 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 30/84 (35%), Gaps = 2/84 (2%) Query: 31 MDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQLGVPATIVVPST 90 ++ P G G G A + + F AG GM+A AAR G I V Sbjct: 176 LELLGPLGCGIQTGAGAVINSLAVRTGSSFASFGAGAVGMSAVMAARIAGATTIIAV--D 233 Query: 91 TPALTIERLKNEGATVKVVGELLD 114 + GAT + + +D Sbjct: 234 IVPSRLALALELGATHAINSKEVD 257 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.127 0.301 Lambda K H 0.267 0.0386 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,387,875 Number of Sequences: 36641 Number of extensions: 366513 Number of successful extensions: 1871 Number of sequences better than 10.0: 88 Number of HSP's better than 10.0 without gapping: 99 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 1511 Number of HSP's gapped (non-prelim): 164 length of query: 328 length of database: 10,336,785 effective HSP length: 97 effective length of query: 231 effective length of database: 6,782,608 effective search space: 1566782448 effective search space used: 1566782448 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)