BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P20023 (1033 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2GSX-A nrPDB 1968 0.0 5FOB-C nrPDB 108 2e-23 6H03-D nrPDB 69 1e-11 1C1Z-A nrPDB 67 3e-11 3ERB-A nrPDB 67 6e-11 4C16-A nrPDB 57 3e-08 2OK5-A nrPDB 55 2e-07 4A5W-B nrPDB 50 4e-06 4FXG-G nrPDB 47 6e-05 1ZJK-A nrPDB 46 1e-04 4LOT-A nrPDB 44 4e-04 4J1Y-A nrPDB 44 4e-04 5UBM-B nrPDB 44 5e-04 4IGD-A nrPDB 42 0.001 4KKD-A nrPDB 42 0.002 2QY0-A nrPDB 41 0.003 1GPZ-A nrPDB 41 0.003 4AQB-A nrPDB 38 0.019 2ZOD-A nrPDB 32 0.97 3KYF-A nrPDB 32 1.7 1Q3X-A nrPDB 32 2.0 1UL9-A nrPDB 31 3.5 3TVJ-A nrPDB 30 3.9 5NW4-X nrPDB 30 3.9 4ZG8-A nrPDB 29 8.7 >2GSX-A nrPDB Length = 951 Score = 1968 bits (5098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 951/951 (100%), Positives = 951/951 (100%) Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP Sbjct: 1 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 60 Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP Sbjct: 61 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 120 Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 200 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS Sbjct: 121 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 180 Query: 201 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 260 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG Sbjct: 181 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 240 Query: 261 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE Sbjct: 241 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 300 Query: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM Sbjct: 301 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 360 Query: 381 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN Sbjct: 361 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 420 Query: 441 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK Sbjct: 421 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 480 Query: 501 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 560 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP Sbjct: 481 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 540 Query: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY Sbjct: 541 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 600 Query: 621 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL 680 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL Sbjct: 601 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL 660 Query: 681 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY Sbjct: 661 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 720 Query: 741 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN 800 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN Sbjct: 721 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN 780 Query: 801 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 860 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG Sbjct: 781 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 840 Query: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG Sbjct: 841 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 900 Query: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 971 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR Sbjct: 901 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 951 Score = 252 bits (643), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 182/592 (30%), Positives = 264/592 (44%), Gaps = 111/592 (18%) Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTS----EGVWTPPVPQ 465 C +PP ILNG + + GT I+YSC+ + L+GE+S+ C + +G W P P+ Sbjct: 3 CGSPPPILNG-RISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 61 Query: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGE-----GYKLSGSVYQECQGTIPWFMEIR 520 C+ + SSC E GYK+ GS Sbjct: 62 CEYF--------------------NKYSSCPEPIVPGGYKIRGST--------------- 86 Query: 521 LCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSND 580 + +G +VT+ C FS+ G ++ C +N+ Sbjct: 87 ------------------------PYRHGDSVTFACK------TNFSMNGNKSVWCQANN 116 Query: 581 QERGTWSGPA--PLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLK 637 W GP P C +S+ ++C + I NG+ S +VT+ C SG+ L Sbjct: 117 M----W-GPTRLPTC-VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV 170 Query: 638 GSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVE--------LVNTSCQDGY 689 G I C + W P CE+ C+ SL P G E N C +GY Sbjct: 171 GEKIINCLSSGKWSAVPPTCEEARCK----SLGRFPNGKVKEPPILRVGVTANFFCDEGY 226 Query: 690 QLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECD 749 +L G C A G+ + K+P+C+ I C PP I+NG+H G N YG+ V+Y CD Sbjct: 227 RLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCD 286 Query: 750 Q------GFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTH 803 F L+GE L+C DS+ G+WSGP+P+C S +CP+P++ G ++ Sbjct: 287 PDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK 346 Query: 804 SAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHT 863 Y++ND V C GF + GS+ IRC+ TW P P C K+ C PP NG Sbjct: 347 DRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE----CQAPPNILNGQKE 402 Query: 864 GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQK 923 ++ RF PG SI YSC+ GY+LVGE + CT EG W+ P P CK C + G Q Sbjct: 403 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC----EATGRQL 458 Query: 924 GLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 975 +P+ + V + C +GY L GS +CQ W + +C+ + P Sbjct: 459 LTKPQHQFVRPDVNS-SCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPP 509 Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 187/668 (27%), Positives = 269/668 (40%), Gaps = 82/668 (12%) Query: 354 PQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGTWEPSAPVCE-- 407 P IL GR +S + ++C F L G K + C GTW+ AP CE Sbjct: 7 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 65 Query: 408 -KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPP-VPQ 465 K P I+ G + R + G S+ ++C + + G +S+ C + +W P +P Sbjct: 66 NKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPT 125 Query: 466 C-KVAACEATGRQLLTKPQHQF-----VRP--DVNSSCGEGYKLSGSVYQECQGTIPWFM 517 C V E ++ H + P V SC GY L G C + W Sbjct: 126 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 185 Query: 518 EIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCT 577 C+E C NG + G T + C+ G + L G + RC Sbjct: 186 VPPTCEEARCKSLGRFPNGKVKEPPI--LRVGVTANFFCDEG------YRLQGPPSSRCV 237 Query: 578 SNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS----- 632 Q G P+C+ S I NG I A Y VT+ C Sbjct: 238 IAGQ--GVAWTKMPVCEEIFCP---SPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEG 292 Query: 633 -GFTLKGSSQIRCKADN----TWDPEIPVCEKET----CQHVRQSLQELPAGSRV----- 678 F L G S +RC D+ TW P CE T C H + + +G + Sbjct: 293 VNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYN 352 Query: 679 ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENF 738 + V +C G+ L G C G W P+C+ C PP I+NG+ F Sbjct: 353 DTVIFACMFGFTLKGSKQIRCN--AQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRF 409 Query: 739 LYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYK 798 G + Y C+ G+ L+GE+ +QC S+ G W+ P PQC V C E Sbjct: 410 DPGTSIKYSCNPGYVLVGEESIQCTSE----GVWTPPVPQC----KVAAC---EATGRQL 458 Query: 799 LNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTP 858 L K + D V C G+ ++GS C W + C + I CPPPP Sbjct: 459 LTKPQHQFVRPD-VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE---ITCPPPPVIY 514 Query: 859 NGNHTGGNIARFSPGMSILYSCDQG------YLLVGEALLLCT----HEGTWSQPAPHCK 908 NG HTG ++ F G ++ Y+C+ G + L+GE+ + CT GTWS PAP CK Sbjct: 515 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 574 Query: 909 ----EVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPP 964 V CS +G + + Y Y VT +C G+ L+GS Q +C++D+ W+P Sbjct: 575 LSLLAVQCSHVHIANGYKISGK-EAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 633 Query: 965 LAVCRSRS 972 + VC + Sbjct: 634 IPVCEKET 641 >5FOB-C nrPDB Length = 245 Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 81/235 (34%), Positives = 112/235 (47%), Gaps = 20/235 (8%) Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235 G ++ Y C GY I +G + C + RC S NG + + G Sbjct: 29 GDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGHLDIGGV-DFG 87 Query: 236 VTANFFCDEGYRLQGPPSSRCVIAGQG-VAWT-KMPVCEEIFCPSPPPILNGRHIGNSLA 293 + + C+ GY L G S C + G + W K P+CE + C PP I NGRH G + Sbjct: 88 SSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHNGYNDF 147 Query: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353 GS+VTY+C+ + LIG S + C+ G WS P P C++ V+CPH Sbjct: 148 YTD-GSVVTYSCNS------GYSLIGNSGVLCS-----GGEWSNP-PTCQI----VKCPH 190 Query: 354 PQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408 P IL G + SG K Y+YND V F C +G+ L GS C+ TW+P P C + Sbjct: 191 PTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 245 Score = 98.2 bits (243), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 85/248 (34%), Positives = 116/248 (46%), Gaps = 31/248 (12%) Query: 422 EDRHMVRFDPGTSIKYSCNPGYVL--VGEESIQCTSEGVWTPPVPQCKVAACEATGRQLL 479 E ++ G +I+Y C PGY +G +CT G WT QC C + + + Sbjct: 19 ETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTG-WTL-FNQCIKRRCPSP--RDI 74 Query: 480 TKPQHQFVRPDVNSS----CGEGYKLSGSVYQECQ----GTIPWFMEIRLCKEITCPPPP 531 D SS C GY L G C+ G++ W + +C+ + C PP Sbjct: 75 DNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPP 134 Query: 532 VIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAP 591 I NG H G + + + G+ VTY+CN G +SLIG S + C+ G WS P P Sbjct: 135 SISNGRHNGYN-DFYTDGSVVTYSCNSG------YSLIGNSGVLCSG-----GEWSNP-P 181 Query: 592 LCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD 651 C++ V+C H I NGY SG + Y YND V F C G+ L GSS C NTW Sbjct: 182 TCQI----VKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQ 237 Query: 652 PEIPVCEK 659 PE+P C + Sbjct: 238 PELPKCVR 245 Score = 95.9 bits (237), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 16/234 (6%) Query: 617 EAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC---QHVRQSLQELP 673 A Y DT+ + C G+ + I K T C K C + + ++ Sbjct: 23 NANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGHLDIG 82 Query: 674 AGSRVELVNTSCQDGYQLTGHAYQMCQDAENG--IWFKKIPLCKVIHCHPPPVIVNGKHT 731 + SC GY L G C+ G +W K P+C+ + C PP I NG+H Sbjct: 83 GVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHN 142 Query: 732 GMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP 791 G + + G+ V+Y C+ G+ L+G + C G WS P P C + +CP+P Sbjct: 143 GY-NDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-----GEWSNP-PTC----QIVKCPHP 191 Query: 792 EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 845 + +GY + +YS+ND V C G+ ++GS C NTW P +P C++ Sbjct: 192 TILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 245 Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 72/246 (29%), Positives = 106/246 (43%), Gaps = 41/246 (16%) Query: 737 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP-EVKH 795 N+ G+ + Y C G+ + + G ++ QC++ RCP+P ++ + Sbjct: 25 NYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFN----QCIKR----RCPSPRDIDN 76 Query: 796 GYKLNKTHSAYSHNDIVYVD--------CNPGFIMNGSRVIRCHTDNT----WVPGVPTC 843 G H DI VD CN G+ + G C +T W P P C Sbjct: 77 G-----------HLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPIC 125 Query: 844 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQP 903 + C PP NG H G N ++ G + YSC+ GY L+G + +LC+ G WS P Sbjct: 126 ---ESVKCQLPPSISNGRHNGYN-DFYTDGSVVTYSCNSGYSLIGNSGVLCS-GGEWSNP 180 Query: 904 APHCKEVNCSSPADMDG-IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962 P C+ V C P ++G + G ++ Y Y V C+ GY L GS S C + W Sbjct: 181 -PTCQIVKCPHPTILNGYLSSGF--KRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQ 237 Query: 963 PPLAVC 968 P L C Sbjct: 238 PELPKC 243 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 52/162 (32%), Positives = 79/162 (48%), Gaps = 16/162 (9%) Query: 350 QCPHPQ-ILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGT----WEPSAP 404 +CP P+ I G + G D + ++ ++C G+ L G + C T W P AP Sbjct: 67 RCPSPRDIDNGHLDIGGVD---FGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAP 123 Query: 405 VCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPV 463 +CE +CQ PP+I NG+ + D G+ + YSCN GY L+G + C S G W+ P Sbjct: 124 ICESVKCQLPPSISNGRHNGYNDFYTD-GSVVTYSCNSGYSLIGNSGVLC-SGGEWSNP- 180 Query: 464 PQCKVAAC---EATGRQLLTKPQHQFVRPD-VNSSCGEGYKL 501 P C++ C L + + + D V+ +C GYKL Sbjct: 181 PTCQIVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKL 222 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 64/228 (28%), Positives = 90/228 (39%), Gaps = 23/228 (10%) Query: 89 SSCPEPIVPGGYKIRGSTP------YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTR 142 S C P P K + S Y GD++ + C + ++ + G T Sbjct: 1 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTL 59 Query: 143 LPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC----L 198 C+ CP+ I NGH ++G + G S+TYSC SGY L+GE C Sbjct: 60 FNQCIK---RRCPSPRDIDNGH---LDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGST 113 Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVK-EPPILRVGVTANFFCDEGYRLQGPPSSRCV 257 S W+ P CE +C+ NG+ G + C+ GY L G C Sbjct: 114 GSMVWNPKAPICESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC- 172 Query: 258 IAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTC 305 G W+ P C+ + CP P ILNG + SY V +TC Sbjct: 173 ---SGGEWSNPPTCQIVKCPH-PTILNGYLSSGFKRSYSYNDNVDFTC 216 Score = 62.8 bits (151), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 47/134 (35%), Positives = 63/134 (47%), Gaps = 12/134 (8%) Query: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74 AP + C PP I NGR + Y+ G+V+ YSC+ + LIG +LC G Sbjct: 122 APICESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGE 176 Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133 W P P C+ CP P + GY G Y + D+V F CK + ++G+ S C Sbjct: 177 WSNP-PTCQIV----KCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCS 231 Query: 134 ANNMWGPTRLPTCV 147 N W P LP CV Sbjct: 232 PGNTWQP-ELPKCV 244 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/188 (29%), Positives = 77/188 (40%), Gaps = 12/188 (6%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82 C SP I NG + + G+ I YSC+ + LIGE C W+ AP C Sbjct: 68 CPSPRDIDNGHLDI--GGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPIC 125 Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTR 142 E P + G + Y G VT++C + +S+ GN V C P Sbjct: 126 E---SVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSNP-- 180 Query: 143 LPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK 202 PTC V +CP P I NG+ +S S + +V ++C+ GY L G C Sbjct: 181 -PTCQIV---KCPH-PTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNT 235 Query: 203 WSAVPPTC 210 W P C Sbjct: 236 WQPELPKC 243 >6H03-D nrPDB Length = 821 Score = 68.9 bits (167), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 40/120 (33%), Positives = 58/120 (48%), Gaps = 4/120 (3%) Query: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 910 CP PP +G F G +++Y+C++GY L+G + C + W HC+++ Sbjct: 549 CPSPPALKDG-FVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKI 607 Query: 911 NCSSPADMDGIQKGLEPRK-MYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969 C P MDGIQ P+K Y G VT+ C G LEG C S +W+P + R Sbjct: 608 ACVLPVLMDGIQS--HPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNAR 665 Score = 53.1 bits (126), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 25/211 (11%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP PP + +G FP G V YTCN G +SLIG RC E W Sbjct: 549 CPSPPALKDGFVQDEGTM-FPVGKNVVYTCNEG------YSLIGNPVARCG----EDLRW 597 Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646 C+ + C + +G + ++ Y + VT C G +L+G S C + Sbjct: 598 LVGEMHCQ----KIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGS 653 Query: 647 DNTWDPEIPVCEKETCQHVRQSL-QELPAGSRVELVNTS---CQDGYQLTGHAYQMCQDA 702 W PE+ + C L Q +P R E + S C+ Y+ G + +C Sbjct: 654 SLKWSPEM---KNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYEC-GPSLDVCAQD 709 Query: 703 ENGIWFKKIPLCK--VIHCHPPPVIVNGKHT 731 E + +CK V+HC + G+ + Sbjct: 710 ERSKRILPLTVCKMHVLHCQGRNYTLTGRDS 740 Score = 46.6 bits (109), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/134 (23%), Positives = 52/134 (38%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410 CP P L+ V + + V++ C G++L G+ RC W C+K Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIA 608 Query: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470 P +++G + + G + SC+ G L G + C S W+P + + Sbjct: 609 CVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQ 668 Query: 471 CEATGRQLLTKPQH 484 E Q + K Q Sbjct: 669 KENPLTQAVPKCQR 682 Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 53/127 (41%), Gaps = 15/127 (11%) Query: 275 FCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGT 334 FCPSPP + +G + + G V YTC+ EG + LIG RC D + Sbjct: 548 FCPSPPALKDG-FVQDEGTMFPVGKNVVYTCN----EG--YSLIGNPVARCGEDLR---- 596 Query: 335 WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCN 394 W C+ + C P ++ G QK YT + V +C G +L+G C Sbjct: 597 WLVGEMHCQ----KIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCG 652 Query: 395 AQGTWEP 401 + W P Sbjct: 653 SSLKWSP 659 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 10/124 (8%) Query: 147 VSVFPLE-CPALPMIHNGHHTSENVGSIAP-GLSVTYSCESGYLLVGEKIINCLSSGKWS 204 +S+ P E CP+ P + +G E G++ P G +V Y+C GY L+G + C +W Sbjct: 541 LSLVPTEFCPSPPALKDGFVQDE--GTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWL 598 Query: 205 AVPPTCEEARCKSLGRFPNGKVKEP--PILRVGVTANFFCDEGYRLQGPPSSRCVIAGQG 262 C++ C L +G P P VG C G L+GP + C G Sbjct: 599 VGEMHCQKIAC-VLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLC---GSS 654 Query: 263 VAWT 266 + W+ Sbjct: 655 LKWS 658 Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 5/115 (4%) Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVA 469 C +PP + +G +D + F G ++ Y+CN GY L+G +C + W C+ Sbjct: 549 CPSPPALKDGFVQDEGTM-FPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKI 607 Query: 470 AC--EATGRQLLTKPQHQF--VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIR 520 AC + + PQ F V V SC G L G C ++ W E++ Sbjct: 608 ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMK 662 Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust. Identities = 36/130 (27%), Positives = 54/130 (41%), Gaps = 9/130 (6%) Query: 784 PVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPT 842 P CP+P +K G+ ++ ++VY CN G+ + G+ V RC D W+ G Sbjct: 545 PTEFCPSPPALKDGFVQDEGTMFPVGKNVVYT-CNEGYSLIGNPVARCGEDLRWLVGEMH 603 Query: 843 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQ 902 C K A + P +G + ++ G + SC G L G + LC WS Sbjct: 604 CQKIACV----LPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWS- 658 Query: 903 PAPHCKEVNC 912 P K C Sbjct: 659 --PEMKNARC 666 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 9/119 (7%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82 C SPP + +G + T VG + Y+C+ + LIG C D W C Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARC----GEDLRWLVGEMHC 604 Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140 + +C P++ G + P Y G+ VT +C S+ G + C ++ W P Sbjct: 605 QKI----ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSP 659 Score = 37.0 bits (84), Expect = 0.041, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 15/132 (11%) Query: 719 CHPPPVIVNG--KHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 776 C PP + +G + G M F G V Y C++G+ L+G +C D + W Sbjct: 549 CPSPPALKDGFVQDEGTM---FPVGKNVVYTCNEGYSLIGNPVARCGEDLR----WLVGE 601 Query: 777 PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTW 836 C + C P + G + + Y+ + V V C+ G + G C + W Sbjct: 602 MHCQK----IACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKW 657 Query: 837 VPGVPT--CIKK 846 P + C++K Sbjct: 658 SPEMKNARCVQK 669 Score = 35.4 bits (80), Expect = 0.12, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 7/93 (7%) Query: 487 VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546 V +V +C EGY L G+ C + W + C++I C PV+ +G + + Sbjct: 569 VGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIAC-VLPVLMDGIQSHPQKPFY 627 Query: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579 G VT +C+ G SL G S C S+ Sbjct: 628 TVGEKVTVSCSGG------MSLEGPSAFLCGSS 654 >1C1Z-A nrPDB Length = 326 Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 77/300 (25%), Positives = 116/300 (38%), Gaps = 31/300 (10%) Query: 90 SCPEPI-VPGGYKIRGSTPYRHGDSVTFACKTNF-SMNGNKSVWCQANNMWGPTRLPTCV 147 +CP+P +P + T Y G+ +T++CK + S G + C +W P C Sbjct: 3 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW-PINTLKCT 61 Query: 148 SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP 207 P CP ++ NG + + ++++SC +G+ L G C GKWS Sbjct: 62 ---PRVCPFAGILENG---AVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPEL 115 Query: 208 PTCEEARCKSLGR--FPNGKVKEPPILRVGV---TANFFCDEGYRLQGPPSSRCVIAGQG 262 P C C F +V +P + TA F C + + G + C G Sbjct: 116 PVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGN- 174 Query: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322 WTK+P C E+ CP P NG + + Y T+ C + L G Sbjct: 175 --WTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHD------GYSLDGPEE 226 Query: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQ---KDRYTYNDTVIFAC 379 + CT K G WS P C+ S + +G V Q K+ + D V F C Sbjct: 227 IECT----KLGNWSA-MPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC 281 Score = 65.5 bits (158), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 75/293 (25%), Positives = 113/293 (38%), Gaps = 28/293 (9%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS-KQIRCNAQGTWEPSAPVCE-K 408 CP P L V K Y + + ++C G+ +G ++ C G W + C + Sbjct: 4 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 63 Query: 409 ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKV 468 C + NG F+ +I +SCN G+ L G +S +CT EG W+P +P C Sbjct: 64 VCPFAGILENGA---VRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 120 Query: 469 AACEATGRQLLT-----KP---QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIR 520 C KP + R C + + G+ C W ++ Sbjct: 121 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW-TKLP 179 Query: 521 LCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSND 580 C+E+ CP P NG + Y T+ C+ G +SL G I CT Sbjct: 180 ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDG------YSLDGPEEIECT--- 230 Query: 581 QERGTWSGPAPLCKLS--LLAVQCSHVHIANGYKISGK-EAPYFYNDTVTFKC 630 + G WS P CK S L + + V+ KI K + + D V+F C Sbjct: 231 -KLGNWSA-MPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC 281 Score = 65.1 bits (157), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 55/245 (22%), Positives = 95/245 (38%), Gaps = 29/245 (11%) Query: 741 GNEVSYECDQGFYLLG-EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKL 799 G E++Y C G+ G +K C G W + +C +P V CP + + Sbjct: 25 GEEITYSCKPGYVSRGGMRKFICPLT----GLWPINTLKC--TPRV--CPFAGILENGAV 76 Query: 800 NKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPN 859 ++ + + + + CN GF +NG+ +C + W P +P C P Sbjct: 77 R--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII--------CPPP 126 Query: 860 GNHTGGNIARFSPGM--------SILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 911 T + + P + ++ C + + G + CT G W++ P C+EV Sbjct: 127 SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTK-LPECREVK 185 Query: 912 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 971 C P+ D + Y T C DGY L+G + +C W+ + C++ Sbjct: 186 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKAS 244 Query: 972 SLAPV 976 PV Sbjct: 245 CKLPV 249 Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 58/244 (23%), Positives = 94/244 (38%), Gaps = 34/244 (13%) Query: 549 GTTVTYTCNPG-PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 607 G +TY+C PG RG I T G W P+ L C I Sbjct: 25 GEEITYSCKPGYVSRGGMRKFICPLT----------GLW----PINTLKCTPRVCPFAGI 70 Query: 608 ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCE------KET 661 + + + Y +T++F C +GF L G+ +C + W PE+PVC Sbjct: 71 LENGAV--RYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSI 128 Query: 662 CQHVRQSLQELPAGSRVELVNTS---CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 718 + + AG+ +T+ C + + G+ C +G W K+P C+ + Sbjct: 129 PTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITC--TTHGNW-TKLPECREVK 185 Query: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778 C P NG Y ++ ++ C G+ L G ++++C G+WS P Sbjct: 186 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTK----LGNWSA-MPS 240 Query: 779 CLRS 782 C S Sbjct: 241 CKAS 244 Score = 37.4 bits (85), Expect = 0.035, Method: Compositional matrix adjust. Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 7/121 (5%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGS-RVIRCHTDNTWVPGVPTCIKK 846 CP P+ + + Y + + C PG++ G R C W C + Sbjct: 4 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 63 Query: 847 AFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPH 906 CP NG F +I +SC+ G+ L G CT EG WS P Sbjct: 64 V---CPFAGILENG---AVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPV 117 Query: 907 C 907 C Sbjct: 118 C 118 >3ERB-A nrPDB Length = 223 Score = 66.6 bits (161), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 3/141 (2%) Query: 330 QKTGTWSGPAPRCELSTSA---VQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK 386 + +G W P LS + V+CP P + + + Y V F C GF L+ Sbjct: 45 KSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILR 104 Query: 387 GSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV 446 GS +C G W+ VC+ PN R RF G ++Y C+ VL Sbjct: 105 GSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 164 Query: 447 GEESIQCTSEGVWTPPVPQCK 467 G +C GVW+ P C+ Sbjct: 165 GSSERECQGNGVWSGTEPICR 185 Score = 63.5 bits (153), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 53/168 (31%), Positives = 74/168 (44%), Gaps = 16/168 (9%) Query: 859 NGNHTGGNIAR---FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPH-------CK 908 N N +GG ++PG + YSC QG L A LC G W P CK Sbjct: 7 NVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCK 65 Query: 909 EVNCSSPADMD-GIQKGLEPR-KMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLA 966 V C +P + GI PR Y G V+ ECEDG++L GSP QC+ + W+ A Sbjct: 66 PVRCPAPVSFENGI---YTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 122 Query: 967 VCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQKE 1014 VC + + GI+ G + F V + + T +S++E Sbjct: 123 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERE 170 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 9/131 (6%) Query: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772 +CK + C P NG +T + ++ G VS+EC+ GF L G QCR + G W Sbjct: 63 VCKPVRCPAPVSFENGIYTPRLG-SYPVGGNVSFECEDGFILRGSPVRQCRPN----GMW 117 Query: 773 SGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT 832 G + C CPNP + G +T + H D V C+ ++ GS C Sbjct: 118 DGETAVCDNG--AGHCPNPGISLGAV--RTGFRFGHGDKVRYRCSSNLVLTGSSERECQG 173 Query: 833 DNTWVPGVPTC 843 + W P C Sbjct: 174 NGVWSGTEPIC 184 Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 15/139 (10%) Query: 270 VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDS 329 VC+ + CP+P NG + L + G V++ C E+G FIL G +C Sbjct: 63 VCKPVRCPAPVSFENGIYT-PRLGSYPVGGNVSFEC----EDG--FILRGSPVRQC---- 111 Query: 330 QKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSK 389 + G W G C+ A CP+P I G + +G R+ + D V + C L GS Sbjct: 112 RPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTG--FRFGHGDKVRYRCSSNLVLTGSS 167 Query: 390 QIRCNAQGTWEPSAPVCEK 408 + C G W + P+C + Sbjct: 168 ERECQGNGVWSGTEPICRQ 186 Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 12/182 (6%) Query: 731 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPV---TR 787 T ++ + G+ ++Y C QG Y +L C+S G W P S V R Sbjct: 14 TFTLSHGWAPGSLLTYSCPQGLYPSPASRL-CKSS----GQWQTPGATRSLSKAVCKPVR 68 Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA 847 CP P +Y V +C GFI+ GS V +C + W C A Sbjct: 69 CPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGA 128 Query: 848 FIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 907 CP P + TG RF G + Y C +L G + C G WS P C Sbjct: 129 GH-CPNPGISLGAVRTG---FRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 184 Query: 908 KE 909 ++ Sbjct: 185 RQ 186 Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 15/139 (10%) Query: 521 LCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSND 580 +CK + CP P NG +T L +P G V++ C G F L G +C N Sbjct: 63 VCKPVRCPAPVSFENGIYT-PRLGSYPVGGNVSFECEDG------FILRGSPVRQCRPN- 114 Query: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640 G W G +C A C + I+ G +G + + D V ++C S L GSS Sbjct: 115 ---GMWDGETAVCDNG--AGHCPNPGISLGAVRTGFR--FGHGDKVRYRCSSNLVLTGSS 167 Query: 641 QIRCKADNTWDPEIPVCEK 659 + C+ + W P+C + Sbjct: 168 ERECQGNGVWSGTEPICRQ 186 Score = 53.1 bits (126), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 12/144 (8%) Query: 581 QERGTWSGPAPLCKLSLLA---VQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL 636 + G W P LS V+C + V NG + + Y V+F+C GF L Sbjct: 45 KSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGI-YTPRLGSYPVGGNVSFECEDGFIL 103 Query: 637 KGSSQIRCKADNTWDPEIPVCEKET--CQHVRQSLQELPAGSRV---ELVNTSCQDGYQL 691 +GS +C+ + WD E VC+ C + SL + G R + V C L Sbjct: 104 RGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVL 163 Query: 692 TGHAYQMCQDAENGIWFKKIPLCK 715 TG + + CQ NG+W P+C+ Sbjct: 164 TGSSERECQG--NGVWSGTEPICR 185 Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 16/194 (8%) Query: 90 SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMW---GPTRLPTC 146 SCP+ + G S + G +T++C + S C+++ W G TR + Sbjct: 3 SCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPS-PASRLCKSSGQWQTPGATRSLSK 61 Query: 147 VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAV 206 P+ CPA NG +T +GS G +V++ CE G++L G + C +G W Sbjct: 62 AVCKPVRCPAPVSFENGIYTPR-LGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGE 120 Query: 207 PPTCEEARCKSLGRFPN-----GKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261 C+ G PN G V+ G + C L G C G Sbjct: 121 TAVCDNG----AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSEREC--QGN 174 Query: 262 GVAWTKMPVCEEIF 275 GV P+C + + Sbjct: 175 GVWSGTEPICRQPY 188 Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 40/155 (25%), Positives = 60/155 (38%), Gaps = 8/155 (5%) Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80 + C +P NG + VG + + C F L G C + +G WD Sbjct: 67 VRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQC----RPNGMWDGETA 122 Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140 C+ N CP P + G +R + HGD V + C +N + G+ CQ N +W Sbjct: 123 VCD--NGAGHCPNPGISLG-AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSG 179 Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175 T P C + + P G S +G+ P Sbjct: 180 TE-PICRQPYSYDFPEDVAPALGTSFSHMLGATNP 213 Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 35/147 (23%), Positives = 61/147 (41%), Gaps = 12/147 (8%) Query: 830 CHTDNTW-VPGVPTCIKKAF---IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 885 C + W PG + KA + CP P NG +T + + G ++ + C+ G++ Sbjct: 44 CKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP-RLGSYPVGGNVSFECEDGFI 102 Query: 886 LVGEALLLCTHEGTWSQPAPHCKEV--NCSSPA-DMDGIQKGLEPRKMYQYGAVVTLECE 942 L G + C G W C +C +P + ++ G + +G V C Sbjct: 103 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFR----FGHGDKVRYRCS 158 Query: 943 DGYMLEGSPQSQCQSDHQWNPPLAVCR 969 +L GS + +CQ + W+ +CR Sbjct: 159 SNLVLTGSSERECQGNGVWSGTEPICR 185 Score = 43.9 bits (102), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 13/144 (9%) Query: 393 CNAQGTWEP-------SAPVCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYV 444 C + G W+ S VC+ C AP + NG R + + G ++ + C G++ Sbjct: 44 CKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPR-LGSYPVGGNVSFECEDGFI 102 Query: 445 LVGEESIQCTSEGVWTPPVPQCKVAA--CEATGRQL-LTKPQHQFVRPD-VNSSCGEGYK 500 L G QC G+W C A C G L + +F D V C Sbjct: 103 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLV 162 Query: 501 LSGSVYQECQGTIPWFMEIRLCKE 524 L+GS +ECQG W +C++ Sbjct: 163 LTGSSERECQGNGVWSGTEPICRQ 186 >4C16-A nrPDB Length = 280 Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Query: 867 IARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGL 925 + FS S SCD+GYL + C G WS P P C V C + + +G + Sbjct: 176 LGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECF 235 Query: 926 EPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRS 970 + + + T +CE+G+ L G+ QC S W+ C++ Sbjct: 236 QNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 280 Score = 56.6 bits (135), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Query: 152 LECPALPMIHNGHHT-SENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210 + C AL +G S +G+ + S + SC+ GYL + + C+SSG+WSA P C Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC 216 Query: 211 EEARCKSLGRFPNGKV---KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261 C ++ NG V + P T F C+EG+ L G S +C +G Sbjct: 217 NVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 270 Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 16/118 (13%) Query: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602 L +F Y ++ + +C+ G + T++C S+ G WS P P C + V+C Sbjct: 176 LGNFSYNSSCSISCDRG------YLPSSMETMQCMSS----GEWSAPIPACNV----VEC 221 Query: 603 SHV-HIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCE 658 V + ANG+ + F +N T TF C GF L G+ ++C + WD E P C+ Sbjct: 222 DAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 16/107 (14%) Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFV 487 F +S SC+ GY+ E++QC S G W+ P+P C V C+A +T P + FV Sbjct: 178 NFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDA-----VTNPANGFV 232 Query: 488 RPDVN-----------SSCGEGYKLSGSVYQECQGTIPWFMEIRLCK 523 N C EG++L G+ +C + W E CK Sbjct: 233 ECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 14/117 (11%) Query: 292 LANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL-STSAVQ 350 L N SY S + +CD ++ T++C +G WS P P C + AV Sbjct: 176 LGNFSYNSSCSISCDR------GYLPSSMETMQC----MSSGEWSAPIPACNVVECDAVT 225 Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE 407 P + G + +N T F C GF L G++ ++C + G W+ P C+ Sbjct: 226 NPANGFVECFQNPGS---FPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%) Query: 806 YSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGN-HTG 864 +S+N + C+ G++ + ++C + W +P C + C NG Sbjct: 179 FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC---NVVECDAVTNPANGFVECF 235 Query: 865 GNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 908 N F + + C++G+ L+G L CT G W P CK Sbjct: 236 QNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 737 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC--LRSPPVTRCPNPEVK 794 NF Y + S CD+G+ + +QC S G WS P P C + VT N V+ Sbjct: 178 NFSYNSSCSISCDRGYLPSSMETMQCMSS----GEWSAPIPACNVVECDAVTNPANGFVE 233 Query: 795 HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTC 843 + ++ N DC GF + G++ ++C + W PTC Sbjct: 234 ----CFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTC 278 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 7/97 (7%) Query: 684 SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE-NFLYGN 742 SC GY + C + G W IP C V+ C NG +F + Sbjct: 188 SCDRGYLPSSMETMQCMSS--GEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNT 245 Query: 743 EVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779 +++C++GF L+G + LQC S G+W P C Sbjct: 246 TCTFDCEEGFELMGAQSLQCTSS----GNWDNEKPTC 278 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 11/102 (10%) Query: 494 SCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG-AHTGSSLEDFPYGTTV 552 SC GY S +C + W I C + C NG + FP+ TT Sbjct: 188 SCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTC 247 Query: 553 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594 T+ C G F L+G +++CTS+ G W P CK Sbjct: 248 TFDCEEG------FELMGAQSLQCTSS----GNWDNEKPTCK 279 Score = 35.0 bits (79), Expect = 0.18, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 19/109 (17%) Query: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVE 679 + YN + + C G+ ++C + W IP C C V PA VE Sbjct: 179 FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTN-----PANGFVE 233 Query: 680 LV--------NTS----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 716 NT+ C++G++L G Q Q +G W + P CK Sbjct: 234 CFQNPGSFPWNTTCTFDCEEGFELMGA--QSLQCTSSGNWDNEKPTCKA 280 Score = 31.2 bits (69), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAV--GTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73 P + C + NG + + P + T + C F L+G +SL C + G Sbjct: 214 PACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSS----G 269 Query: 74 TWDKPAPKCE 83 WD P C+ Sbjct: 270 NWDNEKPTCK 279 Score = 29.6 bits (65), Expect = 7.7, Method: Compositional matrix adjust. Identities = 11/43 (25%), Positives = 20/43 (46%) Query: 927 PRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969 P + Y + ++ C+ GY+ QC S +W+ P+ C Sbjct: 175 PLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 217 >2OK5-A nrPDB Length = 752 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 9/145 (6%) Query: 330 QKTGTWSGPAPRCELSTS-----AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFT 384 + TG+WS + + + A+ CP P + Y +D + F C G+T Sbjct: 62 RSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYT 121 Query: 385 LKGSKQIRCNAQGTWEPSAPVCEKECQ--APPNILNGQKEDRHMVRFDPGTSIKYSCNPG 442 L+GS C G W +C+ + P I G ++ R + S+ Y C+ G Sbjct: 122 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLE--DSVTYHCSRG 179 Query: 443 YVLVGEESIQCTSEGVWTPPVPQCK 467 L G + C G W+ P C+ Sbjct: 180 LTLRGSQRRTCQEGGSWSGTEPSCQ 204 Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 22/172 (12%) Query: 522 CKEITCPPPPVIYNGAHTGSSLEDFPY---GTTVTYTCNPGPERGVEFSLIGESTIRCTS 578 C+ I CP P NG + S PY +++ C G ++L G + C Sbjct: 83 CRAIHCPRPHDFENGEYWPRS----PYYNVSDEISFHCYDG------YTLRGSANRTCQV 132 Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638 N G WSG +C A CS+ I G + G + Y D+VT+ C G TL+G Sbjct: 133 N----GRWSGQTAICDNG--AGYCSNPGIPIGTRKVGSQ--YRLEDSVTYHCSRGLTLRG 184 Query: 639 SSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVN-TSCQDGY 689 S + C+ +W P C+ Q + E S E + +DG+ Sbjct: 185 SQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 236 Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 68/166 (40%), Gaps = 20/166 (12%) Query: 584 GTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKE----APYF-YNDTVTFKCYSGFTLKG 638 G+WS + ++ +C +H + E +PY+ +D ++F CY G+TL+G Sbjct: 65 GSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRG 124 Query: 639 SSQIRCKADNTWDPEIPVCEKET--CQHVRQSLQELPAGSRVEL---VNTSCQDGYQLTG 693 S+ C+ + W + +C+ C + + GS+ L V C G L G Sbjct: 125 SANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRG 184 Query: 694 HAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 739 + CQ E G W P C+ + P V AE FL Sbjct: 185 SQRRTCQ--EGGSWSGTEPSCQDSFMYDTPQEV--------AEAFL 220 Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 45/174 (25%), Positives = 62/174 (35%), Gaps = 13/174 (7%) Query: 741 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP-----VTRCPNPEVKH 795 G + Y C GFY + CRS GSWS Q ++ CP P Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRST----GSWSTLKTQDQKTVRKAECRAIHCPRPHDFE 95 Query: 796 GYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP 855 + Y+ +D + C G+ + GS C + W C A G P Sbjct: 96 NGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA--GYCSNP 153 Query: 856 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKE 909 P G G+ R S+ Y C +G L G C G+WS P C++ Sbjct: 154 GIPIGTRKVGSQYRLED--SVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 205 Score = 49.3 bits (116), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 23/183 (12%) Query: 173 IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP----PTCEEARCKSLG-----RFPN 223 + G ++ Y C SG+ + C S+G WS + T +A C+++ F N Sbjct: 37 LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFEN 96 Query: 224 GKV-KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPI 282 G+ P V +F C +GY L+G + C + G+ T + +C +P Sbjct: 97 GEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP 156 Query: 283 LNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342 + R +G + VTY C L G C Q+ G+WSG P C Sbjct: 157 IGTRKVG---SQYRLEDSVTYHCSR------GLTLRGSQRRTC----QEGGSWSGTEPSC 203 Query: 343 ELS 345 + S Sbjct: 204 QDS 206 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/130 (27%), Positives = 55/130 (42%), Gaps = 9/130 (6%) Query: 714 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773 C+ IHC P NG++ + + +E+S+ C G+ L G C+ + G WS Sbjct: 83 CRAIHCPRPHDFENGEYWP-RSPYYNVSDEISFHCYDGYTLRGSANRTCQVN----GRWS 137 Query: 774 GPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTD 833 G + C C NP + G + K S Y D V C+ G + GS+ C Sbjct: 138 GQTAIC--DNGAGYCSNPGIPIGTR--KVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG 193 Query: 834 NTWVPGVPTC 843 +W P+C Sbjct: 194 GSWSGTEPSC 203 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/184 (26%), Positives = 72/184 (39%), Gaps = 32/184 (17%) Query: 432 GTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQF----- 486 G +++Y C G+ ++ C S G W+ Q + +A R + H F Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 99 Query: 487 --------VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT--CPPPPVIYNG 536 V +++ C +GY L GS + CQ W + +C C P + Sbjct: 100 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 159 Query: 537 AHTGSS--LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594 GS LED +VTY C+ G +L G C QE G+WSG P C+ Sbjct: 160 RKVGSQYRLED-----SVTYHCSRG------LTLRGSQRRTC----QEGGSWSGTEPSCQ 204 Query: 595 LSLL 598 S + Sbjct: 205 DSFM 208 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 12/115 (10%) Query: 864 GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQ---------PAPHCKEVNCSS 914 GG+ G ++ Y C G+ C G+WS C+ ++C Sbjct: 31 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPR 90 Query: 915 PADMDGIQKGLEPRK-MYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968 P D + + PR Y ++ C DGY L GS CQ + +W+ A+C Sbjct: 91 PHDFENGE--YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 143 Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 108 YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTS 167 Y D ++F C +++ G+ + CQ N W P +P+ + Sbjct: 106 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI------GT 159 Query: 168 ENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213 VGS SVTY C G L G + C G WS P+C+++ Sbjct: 160 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 206 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 43/191 (22%), Positives = 77/191 (40%), Gaps = 13/191 (6%) Query: 99 GYKIRGST--PYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156 G +I+G + + G ++ + C + F ++ C++ W + +V EC A Sbjct: 26 GVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRA 85 Query: 157 L--PMIHNGHHTSENVGSIAPGLS--VTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEE 212 + P H+ + S +S +++ C GY L G C +G+WS C+ Sbjct: 86 IHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN 145 Query: 213 AR--CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM-P 269 C + G P G K R+ + + C G L+G C +G +W+ P Sbjct: 146 GAGYCSNPG-IPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEP 201 Query: 270 VCEEIFCPSPP 280 C++ F P Sbjct: 202 SCQDSFMYDTP 212 Score = 38.5 bits (88), Expect = 0.015, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 6/116 (5%) Query: 849 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 908 I CP P NG + + ++ I + C GY L G A C G WS C Sbjct: 86 IHCPRPHDFENGEYWPRS-PYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 144 Query: 909 EVN--CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962 CS+P G +K Y+ VT C G L GS + CQ W+ Sbjct: 145 NGAGYCSNPGIPIGTRK---VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWS 197 >4A5W-B nrPDB Length = 913 Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 7/153 (4%) Query: 815 DCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGM 874 DC + N + C D+ + V +A GCP P NG + G Sbjct: 589 DCTFSIMENNGQP--CINDDEEMKEVDLPEIEADSGCPQPVPPENG-FIRNEKQLYLVGE 645 Query: 875 SILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEP-RKMYQY 933 + SC G+ VG C +GTW Q C+ C P + + + P +++Y+ Sbjct: 646 DVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLT--ITPFQRLYRI 703 Query: 934 GAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLA 966 G + L C G+++ G + CQ + W PP++ Sbjct: 704 GESIELTCPKGFVVAGPSRYTCQGN-SWTPPIS 735 Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/230 (22%), Positives = 80/230 (34%), Gaps = 34/230 (14%) Query: 244 EGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIF-------CPSPPPILNGRHIGNSLANVS 296 E Q P + GQ W+ C+ + C +P P G+ Sbjct: 529 ENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEG------ 582 Query: 297 YGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQI 356 + EE F ++ + C D ++ P E+ + CP P Sbjct: 583 ---------EKRQEEDCTFSIMENNGQPCINDDEEMKEVDLP----EIEADS-GCPQPVP 628 Query: 357 LRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP-- 413 + +K Y + V +C+ GF G + RC GTW C++ EC P Sbjct: 629 PENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVV 688 Query: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPV 463 +L R + G SI+ +C G+V+ G C WTPP+ Sbjct: 689 QEVLTITPFQR---LYRIGESIELTCPKGFVVAGPSRYTCQGNS-WTPPI 734 Score = 36.2 bits (82), Expect = 0.085, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%) Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARC-KSLGRFPNGKVKEPPILRV 234 G V SC +G+ VG + CL G W C+ C K + + + R+ Sbjct: 644 GEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRI 703 Query: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT 266 G + C +G+ + GP C QG +WT Sbjct: 704 GESIELTCPKGFVVAGPSRYTC----QGNSWT 731 Score = 35.4 bits (80), Expect = 0.11, Method: Compositional matrix adjust. Identities = 41/180 (22%), Positives = 70/180 (38%), Gaps = 34/180 (18%) Query: 545 DFPYGTTVTYTCN-PGPERG-------------VEFSLIGESTIRCTSNDQERGTWSGPA 590 D Y + T CN P P+RG FS++ + C ++D+E Sbjct: 557 DATYKRSRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEE-------- 608 Query: 591 PLCKLSLLAVQCSH-----VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645 + ++ L ++ V NG+ I ++ Y + V C +GF G RC Sbjct: 609 -MKEVDLPEIEADSGCPQPVPPENGF-IRNEKQLYLVGEDVEISCLTGFETVGYQYFRCL 666 Query: 646 ADNTWDPEIPVCEKETC-QHVRQSLQELPAGSRV----ELVNTSCQDGYQLTGHAYQMCQ 700 D TW C++ C + V Q + + R+ E + +C G+ + G + CQ Sbjct: 667 PDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQ 726 >4FXG-G nrPDB Length = 154 Score = 46.6 bits (109), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 62/142 (43%), Gaps = 11/142 (7%) Query: 850 GCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQP 903 CP P PNG H A++ S C+ GY L+ L L C +G+W +P Sbjct: 9 ACPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRP 67 Query: 904 APHCKEVNCSSPADM-DGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDHQ 960 P C V+C P D+ G + + + Y AV+ CE+ + M + C++D Sbjct: 68 MPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGF 127 Query: 961 WNPPLAVCRSRSLAPVLCGIAA 982 W +S + +CG++A Sbjct: 128 WTSSKGE-KSLPVCEPVCGLSA 148 Score = 38.5 bits (88), Expect = 0.017, Method: Compositional matrix adjust. Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 18/142 (12%) Query: 345 STSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL-KGSKQIR-----CNAQGT 398 +++A CP+P VS + +Y D+ C G+ L +G ++ C G+ Sbjct: 4 TSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGS 63 Query: 399 WEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTS-----IKYSCNPGY--VLVGEES 450 W+ P C +C P ++ +G+ E PG + I+YSC + + V + Sbjct: 64 WDRPMPACSIVDCGPPDDLPSGRVE----YITGPGVTTYKAVIQYSCEETFYTMKVNDGK 119 Query: 451 IQCTSEGVWTPPVPQCKVAACE 472 C ++G WT + + CE Sbjct: 120 YVCEADGFWTSSKGEKSLPVCE 141 Score = 37.7 bits (86), Expect = 0.028, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 16/109 (14%) Query: 685 CQDGYQL-TGHA-----YQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENF 738 C+ GY+L GH +CQ ++G W + +P C ++ C PP + +G+ + Sbjct: 38 CETGYELLQGHLPLKSFTAVCQ--KDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGV 95 Query: 739 -LYGNEVSYECDQGFYLL--GEKKLQCRSD-----SKGHGSWSGPSPQC 779 Y + Y C++ FY + + K C +D SKG S P C Sbjct: 96 TTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVC 144 Score = 33.1 bits (74), Expect = 0.57, Method: Compositional matrix adjust. Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 15/101 (14%) Query: 330 QKTGTWSGPAPRCELSTSAVQCPHPQIL---RGRMVSGQKDRYTYNDTVIFACMFGF-TL 385 QK G+W P P C S V C P L R ++G TY + ++C F T+ Sbjct: 59 QKDGSWDRPMPAC----SIVDCGPPDDLPSGRVEYITG-PGVTTYKAVIQYSCEETFYTM 113 Query: 386 K-GSKQIRCNAQGTW-----EPSAPVCEKECQAPPNILNGQ 420 K + C A G W E S PVCE C G+ Sbjct: 114 KVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGR 154 Score = 31.2 bits (69), Expect = 2.3, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 13/72 (18%) Query: 21 ISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRL--IGEKSLLCITKDKVDGTW- 75 + CG P + +GR+ Y + P VI+YSC TF + + +C + DG W Sbjct: 74 VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVC----EADGFWT 129 Query: 76 ----DKPAPKCE 83 +K P CE Sbjct: 130 SSKGEKSLPVCE 141 Score = 30.8 bits (68), Expect = 3.3, Method: Compositional matrix adjust. Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 17/136 (12%) Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY-LLVGEKIIN-----CLSSGKWSAVP 207 CP PM H S S + CE+GY LL G + C G W Sbjct: 10 CP-YPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 68 Query: 208 PTCEEARCKSLGRFPNGKVKE---PPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVA 264 P C C P+G+V+ P + + C+E + + V G Sbjct: 69 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGF- 127 Query: 265 WT------KMPVCEEI 274 WT +PVCE + Sbjct: 128 WTSSKGEKSLPVCEPV 143 Score = 30.4 bits (67), Expect = 4.3, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 13/87 (14%) Query: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGY--KIRGSTPYRHGDSVTFACKTNF---SMNG 126 DG+WD+P P C + P +P G I G + + ++C+ F +N Sbjct: 61 DGSWDRPMPACSIVD---CGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVND 117 Query: 127 NKSVWCQANNMW----GPTRLPTCVSV 149 K V C+A+ W G LP C V Sbjct: 118 GKYV-CEADGFWTSSKGEKSLPVCEPV 143 Score = 30.4 bits (67), Expect = 4.4, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 12/80 (15%) Query: 609 NGYKISGKEAPYFYNDTVTFKCYSGFTL-KGSSQIR-----CKADNTWDPEIPVCEKETC 662 NG+ +S +A Y D+ + C +G+ L +G ++ C+ D +WD +P C C Sbjct: 18 NGH-VSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDC 76 Query: 663 QHVRQSLQELPAGSRVELVN 682 +LP+G RVE + Sbjct: 77 ----GPPDDLPSG-RVEYIT 91 >1ZJK-A nrPDB Length = 403 Score = 45.8 bits (107), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 11/141 (7%) Query: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQPA 904 CP P PNG H A++ S C+ GY L+ L L C +G+W +P Sbjct: 17 CPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 75 Query: 905 PHCKEVNCSSPADM-DGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDHQW 961 P C V+C P D+ G + + + Y AV+ CE+ + M + C++D W Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 135 Query: 962 NPPLAVCRSRSLAPVLCGIAA 982 +S + +CG++A Sbjct: 136 TSSKGE-KSLPVCEPVCGLSA 155 Score = 36.6 bits (83), Expect = 0.065, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 16/116 (13%) Query: 685 CQDGYQL-TGHA-----YQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENF 738 C+ GY+L GH +CQ ++G W + +P C ++ C PP + +G+ + Sbjct: 45 CETGYELLQGHLPLKSFTAVCQ--KDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGV 102 Query: 739 -LYGNEVSYECDQGFYLL--GEKKLQCRSD-----SKGHGSWSGPSPQCLRSPPVT 786 Y + Y C++ FY + + K C +D SKG S P C S T Sbjct: 103 TTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTT 158 Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 15/101 (14%) Query: 330 QKTGTWSGPAPRCELSTSAVQCPHPQIL---RGRMVSGQKDRYTYNDTVIFACMFGF-TL 385 QK G+W P P C S V C P L R ++G TY + ++C F T+ Sbjct: 66 QKDGSWDRPMPAC----SIVDCGPPDDLPSGRVEYITG-PGVTTYKAVIQYSCEETFYTM 120 Query: 386 K-GSKQIRCNAQGTW-----EPSAPVCEKECQAPPNILNGQ 420 K + C A G W E S PVCE C GQ Sbjct: 121 KVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGQ 161 Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 13/72 (18%) Query: 21 ISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRL--IGEKSLLCITKDKVDGTW- 75 + CG P + +GR+ Y + P VI+YSC TF + + +C + DG W Sbjct: 81 VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVC----EADGFWT 136 Query: 76 ----DKPAPKCE 83 +K P CE Sbjct: 137 SSKGEKSLPVCE 148 Score = 30.4 bits (67), Expect = 4.4, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 13/84 (15%) Query: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGY--KIRGSTPYRHGDSVTFACKTNF---SMNG 126 DG+WD+P P C + P +P G I G + + ++C+ F +N Sbjct: 68 DGSWDRPMPACSIVD---CGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVND 124 Query: 127 NKSVWCQANNMW----GPTRLPTC 146 K V C+A+ W G LP C Sbjct: 125 GKYV-CEADGFWTSSKGEKSLPVC 147 Score = 29.6 bits (65), Expect = 6.6, Method: Compositional matrix adjust. Identities = 28/112 (25%), Positives = 41/112 (36%), Gaps = 16/112 (14%) Query: 178 SVTYSCESGY-LLVGEKIIN-----CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKE--- 228 S + CE+GY LL G + C G W P C C P+G+V+ Sbjct: 40 SFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITG 99 Query: 229 PPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT------KMPVCEEI 274 P + + C+E + + V G WT +PVCE + Sbjct: 100 PGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGF-WTSSKGEKSLPVCEPV 150 Score = 29.6 bits (65), Expect = 6.8, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 12/80 (15%) Query: 609 NGYKISGKEAPYFYNDTVTFKCYSGF-TLKGSSQIR-----CKADNTWDPEIPVCEKETC 662 NG+ +S +A Y D+ + C +G+ L+G ++ C+ D +WD +P C C Sbjct: 25 NGH-VSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDC 83 Query: 663 QHVRQSLQELPAGSRVELVN 682 +LP+G RVE + Sbjct: 84 ----GPPDDLPSG-RVEYIT 98 >4LOT-A nrPDB Length = 249 Score = 43.9 bits (102), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%) Query: 366 KDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILN 418 K +Y + D V C+ GF + S C + G W S C+ +C P +I N Sbjct: 134 KAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIEN 193 Query: 419 GQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT-----PPVPQC 466 G+ ED F G+ I+Y+C Y + G C G W P +P+C Sbjct: 194 GKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKC 247 Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 17/103 (16%) Query: 679 ELVNTSCQDGYQLT------GHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTG 732 ++V +C DG+++ Y CQ NG W C+ + C P I NGK Sbjct: 141 DVVQITCLDGFEVVEGRVGATSFYSTCQ--SNGKWSNSKLKCQPVDCGIPESIENGKVED 198 Query: 733 MMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSW 772 E+ L+G+ + Y C++ +Y + G + C G+GSW Sbjct: 199 --PESTLFGSVIRYTCEEPYYYMENGGGGEYHC----AGNGSW 235 Score = 33.9 bits (76), Expect = 0.40, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 179 VTYSCESGYLLVGEKI------INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL 232 V +C G+ +V ++ C S+GKWS C+ C NGKV++P Sbjct: 143 VQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPEST 202 Query: 233 RVGVTANFFCDEGY 246 G + C+E Y Sbjct: 203 LFGSVIRYTCEEPY 216 >4J1Y-A nrPDB Length = 397 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%) Query: 366 KDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILN 418 K +Y + D V C+ GF + S C + G W S C+ +C P +I N Sbjct: 17 KAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIEN 76 Query: 419 GQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT-----PPVPQC 466 G+ ED F G+ I+Y+C Y + G C G W P +P+C Sbjct: 77 GKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKC 130 Score = 39.7 bits (91), Expect = 0.008, Method: Compositional matrix adjust. Identities = 37/128 (28%), Positives = 57/128 (44%), Gaps = 22/128 (17%) Query: 679 ELVNTSCQDGYQLT------GHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTG 732 ++V +C DG+++ Y CQ NG W C+ + C P I NGK Sbjct: 24 DVVQITCLDGFEVVEGRVGATSFYSTCQ--SNGKWSNSKLKCQPVDCGIPESIENGKVED 81 Query: 733 MMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSWS----GPS-PQCLRSPP 784 E+ L+G+ + Y C++ +Y + G + C G+GSW GP P+C+ Sbjct: 82 --PESTLFGSVIRYTCEEPYYYMENGGGGEYHC----AGNGSWVNEVLGPELPKCVPVCG 135 Query: 785 VTRCPNPE 792 V R P E Sbjct: 136 VPREPFEE 143 Score = 33.9 bits (76), Expect = 0.38, Method: Compositional matrix adjust. Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 15/131 (11%) Query: 179 VTYSCESGYLLVGEKI------INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL 232 V +C G+ +V ++ C S+GKWS C+ C NGKV++P Sbjct: 26 VQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPEST 85 Query: 233 RVGVTANFFCDEG-YRLQGPPSSRCVIAGQGVAWT------KMPVCEEI-FCPSPPPILN 284 G + C+E Y ++ AG G +W ++P C + P P Sbjct: 86 LFGSVIRYTCEEPYYYMENGGGGEYHCAGNG-SWVNEVLGPELPKCVPVCGVPREPFEEK 144 Query: 285 GRHIGNSLANV 295 R IG S A++ Sbjct: 145 ARAIGGSDADI 155 >5UBM-B nrPDB Length = 152 Score = 43.5 bits (101), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%) Query: 366 KDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILN 418 K +Y + D V C+ GF + S C + G W S C+ +C P +I N Sbjct: 24 KAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIEN 83 Query: 419 GQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT-----PPVPQC 466 G+ ED F G+ I+Y+C Y + G C G W P +P+C Sbjct: 84 GKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKC 137 Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 17/103 (16%) Query: 679 ELVNTSCQDGYQLT------GHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTG 732 ++V +C DG+++ Y CQ NG W C+ + C P I NGK Sbjct: 31 DVVQITCLDGFEVVEGRVGATSFYSTCQS--NGKWSNSKLKCQPVDCGIPESIENGKVED 88 Query: 733 MMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSW 772 E+ L+G+ + Y C++ +Y + G + C G+GSW Sbjct: 89 --PESTLFGSVIRYTCEEPYYYMENGGGGEYHC----AGNGSW 125 Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 179 VTYSCESGYLLVGEKI------INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL 232 V +C G+ +V ++ C S+GKWS C+ C NGKV++P Sbjct: 33 VQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPEST 92 Query: 233 RVGVTANFFCDEGY 246 G + C+E Y Sbjct: 93 LFGSVIRYTCEEPY 106 >4IGD-A nrPDB Length = 406 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 23/136 (16%) Query: 345 STSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGT 398 S + +CP Q + + +Y + D V+ +C G+ + + QI C GT Sbjct: 2 SMTGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGT 61 Query: 399 WEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDP-------GTSIKYSCN-PGYVLVGEE 449 W P C+ +C+AP + +G ++ F + IKYSC P Y ++ Sbjct: 62 WSNKIPTCKIVDCRAPGELEHG------LITFSTRNNLTTYKSEIKYSCQEPYYKMLNNN 115 Query: 450 S--IQCTSEGVWTPPV 463 + C+++GVW V Sbjct: 116 TGIYTCSAQGVWMNKV 131 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 681 VNTSCQDGYQLTGHAYQM----CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 736 V SC GY++ +M + ++G W KIP CK++ C P + +G T Sbjct: 32 VLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRN 91 Query: 737 NF-LYGNEVSYECDQGFYLL 755 N Y +E+ Y C + +Y + Sbjct: 92 NLTTYKSEIKYSCQEPYYKM 111 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Query: 868 ARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQPAPHCKEVNCSSPADMD-G 920 A++ +L SCD GY ++ + + + C +GTWS P CK V+C +P +++ G Sbjct: 24 AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHG 83 Query: 921 IQKGLEPRKMYQYGAVVTLECEDGY 945 + + Y + + C++ Y Sbjct: 84 LITFSTRNNLTTYKSEIKYSCQEPY 108 Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 14/114 (12%) Query: 612 KISGKEAPYFYNDTVTFKCYSGFTLKGSS------QIRCKADNTWDPEIPVCEKETCQHV 665 KI +A YF+ D V C +G+ + + QI C D TW +IP C+ C+ Sbjct: 18 KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAP 77 Query: 666 RQSLQELPAGS-RVELVNTSCQDGYQLTGHAYQMCQD-------AENGIWFKKI 711 + L S R L + Y Y+M + + G+W K+ Sbjct: 78 GELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKV 131 Score = 37.4 bits (85), Expect = 0.038, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 18/118 (15%) Query: 795 HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVPTCIKKAF 848 HG K+ + + Y D V V C+ G+ + V I C D TW +PTC Sbjct: 16 HG-KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTC---KI 71 Query: 849 IGCPPPPKTPNG---NHTGGNIARFSPGMSILYSCDQGY---LLVGEALLLCTHEGTW 900 + C P + +G T N+ + I YSC + Y L + C+ +G W Sbjct: 72 VDCRAPGELEHGLITFSTRNNLTTYKS--EIKYSCQEPYYKMLNNNTGIYTCSAQGVW 127 Score = 36.6 bits (83), Expect = 0.060, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 23/88 (26%) Query: 153 ECPAL-PMIHNGHHTSENVGSIAPGLS-------VTYSCESGYLLVGEKI------INCL 198 ECP L P +H G I P + V SC++GY ++ + + I CL Sbjct: 7 ECPELQPPVH---------GKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL 57 Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKV 226 G WS PTC+ C++ G +G + Sbjct: 58 KDGTWSNKIPTCKIVDCRAPGELEHGLI 85 Score = 34.3 bits (77), Expect = 0.28, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 438 SCNPGYVLVGEE------SIQCTSEGVWTPPVPQCKVAACEATGR------QLLTKPQHQ 485 SC+ GY ++ + I+C +G W+ +P CK+ C A G T+ Sbjct: 35 SCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLT 94 Query: 486 FVRPDVNSSCGEGY 499 + ++ SC E Y Sbjct: 95 TYKSEIKYSCQEPY 108 Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust. Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 19/148 (12%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P ++G+ I S A + V +CD + + + + + C D GTW Sbjct: 8 CPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKD----GTW 62 Query: 336 SGPAPRCELSTSAVQCPHPQILRGRMV--SGQKDRYTYNDTVIFACM---FGFTLKGSKQ 390 S P C++ V C P L ++ S + + TY + ++C + + Sbjct: 63 SNKIPTCKI----VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGI 118 Query: 391 IRCNAQGTWE-----PSAPVCEKECQAP 413 C+AQG W S P C C P Sbjct: 119 YTCSAQGVWMNKVLGRSLPTCLPVCGLP 146 Score = 29.3 bits (64), Expect = 8.4, Method: Compositional matrix adjust. Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 486 FVRPDVNSSCGEGYKL-----SGSVYQ-ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHT 539 F + V SC GYK+ +Q EC W +I CK + C P + +G T Sbjct: 27 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLIT 86 Query: 540 GSSLEDF-PYGTTVTYTCN 557 S+ + Y + + Y+C Sbjct: 87 FSTRNNLTTYKSEIKYSCQ 105 >4KKD-A nrPDB Length = 433 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 681 VNTSCQDGYQLTGHAYQM----CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 736 V SC GY++ +M + ++G W KIP CK++ C P + +G T Sbjct: 30 VLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRN 89 Query: 737 NF-LYGNEVSYECDQGFYLL 755 N Y +E+ Y C + +Y + Sbjct: 90 NLTTYKSEIKYSCQEPYYKM 109 Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Query: 868 ARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQPAPHCKEVNCSSPADMD-G 920 A++ +L SCD GY ++ + + + C +GTWS P CK V+C +P +++ G Sbjct: 22 AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHG 81 Query: 921 IQKGLEPRKMYQYGAVVTLECEDGY 945 + + Y + + C++ Y Sbjct: 82 LITFSTRNNLTTYKSEIKYSCQEPY 106 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 23/131 (17%) Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTWEPSA 403 +CP Q + + +Y + D V+ +C G+ + + QI C GTW Sbjct: 5 ECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKI 64 Query: 404 PVCE-KECQAPPNILNGQKEDRHMVRFDP-------GTSIKYSCN-PGYVLVGEES--IQ 452 P C+ +C+AP + +G ++ F + IKYSC P Y ++ + Sbjct: 65 PTCKIVDCRAPGELEHG------LITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 118 Query: 453 CTSEGVWTPPV 463 C+++GVW V Sbjct: 119 CSAQGVWMNKV 129 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 14/114 (12%) Query: 612 KISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEIPVCEKETCQHV 665 KI +A YF+ D V C +G+ + + QI C D TW +IP C+ C+ Sbjct: 16 KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAP 75 Query: 666 RQSLQELPAGS-RVELVNTSCQDGYQLTGHAYQMCQD-------AENGIWFKKI 711 + L S R L + Y Y+M + + G+W K+ Sbjct: 76 GELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKV 129 Score = 37.4 bits (85), Expect = 0.036, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 18/118 (15%) Query: 795 HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVPTCIKKAF 848 HG K+ + + Y D V V C+ G+ + V I C D TW +PTC Sbjct: 14 HG-KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTC---KI 69 Query: 849 IGCPPPPKTPNG---NHTGGNIARFSPGMSILYSCDQGY---LLVGEALLLCTHEGTW 900 + C P + +G T N+ + I YSC + Y L + C+ +G W Sbjct: 70 VDCRAPGELEHGLITFSTRNNLTTYKS--EIKYSCQEPYYKMLNNNTGIYTCSAQGVW 125 Score = 36.6 bits (83), Expect = 0.058, Method: Compositional matrix adjust. Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 19/152 (12%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P ++G+ I S A + V +CD + + + + + C K GTW Sbjct: 6 CPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL----KDGTW 60 Query: 336 SGPAPRCELSTSAVQCPHPQILRGRMV--SGQKDRYTYNDTVIFACM---FGFTLKGSKQ 390 S P C++ V C P L ++ S + + TY + ++C + + Sbjct: 61 SNKIPTCKI----VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGI 116 Query: 391 IRCNAQGTWE-----PSAPVCEKECQAPPNIL 417 C+AQG W S P C EC P L Sbjct: 117 YTCSAQGVWMNKVLGRSLPTCLPECGQPSRSL 148 Score = 36.2 bits (82), Expect = 0.068, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 23/88 (26%) Query: 153 ECPAL-PMIHNGHHTSENVGSIAPGLS-------VTYSCESGYLLVGEKI------INCL 198 ECP L P +H G I P + V SC++GY ++ + + I CL Sbjct: 5 ECPELQPPVH---------GKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL 55 Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKV 226 G WS PTC+ C++ G +G + Sbjct: 56 KDGTWSNKIPTCKIVDCRAPGELEHGLI 83 Score = 33.9 bits (76), Expect = 0.41, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 435 IKYSCNPGYVLVGEE------SIQCTSEGVWTPPVPQCKVAACEATGR------QLLTKP 482 + SC+ GY ++ + I+C +G W+ +P CK+ C A G T+ Sbjct: 30 VLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRN 89 Query: 483 QHQFVRPDVNSSCGEGY 499 + ++ SC E Y Sbjct: 90 NLTTYKSEIKYSCQEPY 106 >2QY0-A nrPDB Length = 159 Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 16/92 (17%) Query: 684 SCQDGYQLTG-----HAY-QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNG--KHTGMMA 735 +C+ GYQL H++ +CQD +G W + +P CK+ C P + NG ++T M Sbjct: 33 TCKQGYQLIEGNQVLHSFTAVCQD--DGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMG 90 Query: 736 ENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK 767 N Y + Y C + +Y K+Q R+ S+ Sbjct: 91 VN-TYKARIQYYCHEPYY-----KMQTRAGSR 116 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 6/49 (12%) Query: 876 ILYSCDQGYLLV-GEALL-----LCTHEGTWSQPAPHCKEVNCSSPADM 918 + +C QGY L+ G +L +C +GTW + P CK +C P ++ Sbjct: 30 FIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNL 78 Score = 33.9 bits (76), Expect = 0.33, Method: Compositional matrix adjust. Identities = 31/137 (22%), Positives = 49/137 (35%), Gaps = 32/137 (23%) Query: 788 CPNPEVKHGYKL-NKTHSAYSHNDIVYVDCNPGF-IMNGSRVIR-----CHTDNTWVPGV 840 CP P+ + + Y D C G+ ++ G++V+ C D TW + Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 64 Query: 841 PTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGM-------SILYSCDQGYLLVG----- 888 P C K C P PNG+ R++ M I Y C + Y + Sbjct: 65 PRCKIK---DCGQPRNLPNGDF------RYTTTMGVNTYKARIQYYCHEPYYKMQTRAGS 115 Query: 889 ----EALLLCTHEGTWS 901 + + CT +G W Sbjct: 116 RESEQGVYTCTAQGIWK 132 Score = 31.6 bits (70), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 10/84 (11%) Query: 182 SCESGYLLV-GEKIIN-----CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235 +C+ GY L+ G ++++ C G W P C+ C PNG + + V Sbjct: 33 TCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVN 92 Query: 236 ---VTANFFCDE-GYRLQGPPSSR 255 ++C E Y++Q SR Sbjct: 93 TYKARIQYYCHEPYYKMQTRAGSR 116 >1GPZ-A nrPDB Length = 399 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 16/93 (17%) Query: 683 TSCQDGYQLTG-----HAY-QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNG--KHTGMM 734 +C+ GYQL H++ +CQD +G W + +P CK+ C P + NG ++T M Sbjct: 30 ATCKQGYQLIEGNQVLHSFTAVCQD--DGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTM 87 Query: 735 AENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK 767 N Y + Y C + +Y K+Q R+ S+ Sbjct: 88 GVN-TYKARIQYYCHEPYY-----KMQTRAGSR 114 Score = 34.3 bits (77), Expect = 0.32, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 6/49 (12%) Query: 876 ILYSCDQGYLLV-GEALL-----LCTHEGTWSQPAPHCKEVNCSSPADM 918 + +C QGY L+ G +L +C +GTW + P CK +C P ++ Sbjct: 28 FIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNL 76 Score = 33.9 bits (76), Expect = 0.36, Method: Compositional matrix adjust. Identities = 36/159 (22%), Positives = 57/159 (35%), Gaps = 38/159 (23%) Query: 787 RCPNPEVKHGYKL-NKTHSAYSHNDIVYVDCNPGF-IMNGSRVIR-----CHTDNTWVPG 839 +CP P+ + + Y D C G+ ++ G++V+ C D TW Sbjct: 2 KCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 61 Query: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGM-------SILYSCDQGYLLVG---- 888 +P C K C P PNG+ R++ M I Y C + Y + Sbjct: 62 MPRCKIK---DCGQPRNLPNGDF------RYTTTMGVNTYKARIQYYCHEPYYKMQTRAG 112 Query: 889 -----EALLLCTHEGTWS-----QPAPHCKEVNCSSPAD 917 + + CT +G W + P C V C P + Sbjct: 113 SRESEQGVYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVN 150 Score = 31.2 bits (69), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 10/84 (11%) Query: 182 SCESGYLLV-GEKIIN-----CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235 +C+ GY L+ G ++++ C G W P C+ C PNG + + V Sbjct: 31 TCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVN 90 Query: 236 ---VTANFFCDE-GYRLQGPPSSR 255 ++C E Y++Q SR Sbjct: 91 TYKARIQYYCHEPYYKMQTRAGSR 114 >4AQB-A nrPDB Length = 361 Score = 38.1 bits (87), Expect = 0.019, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 6/54 (11%) Query: 612 KISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEIPVCEK 659 KI +A YF+ D V C +G+ + + QI C D TW +IP C+K Sbjct: 292 KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKK 345 Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 341 RCELSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRC 393 R + +CP Q + G++ Q +Y + D V+ +C G+ + + QI C Sbjct: 272 RLSYRAAGNECPELQPPVHGKIEPSQA-KYFFKDQVLVSCDTGYKVLKDNVEMDTFQIEC 330 Query: 394 NAQGTWEPSAPVCEK 408 GTW P C+K Sbjct: 331 LKDGTWSNKIPTCKK 345 Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 23/90 (25%) Query: 153 ECPAL-PMIHNGHHTSENVGSIAPGLS-------VTYSCESGYLLVGEKI------INCL 198 ECP L P +H G I P + V SC++GY ++ + + I CL Sbjct: 281 ECPELQPPVH---------GKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL 331 Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKE 228 G WS PTC++ + +V E Sbjct: 332 KDGTWSNKIPTCKKNEIDLESELKSEQVTE 361 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 7/57 (12%) Query: 795 HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVPTCIK 845 HG K+ + + Y D V V C+ G+ + V I C D TW +PTC K Sbjct: 290 HG-KIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKK 345 Score = 31.6 bits (70), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 868 ARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQPAPHCKEVNCSSPADMDGI 921 A++ +L SCD GY ++ + + + C +GTWS P CK+ +++ Sbjct: 298 AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKKNEIDLESELKSE 357 Query: 922 Q 922 Q Sbjct: 358 Q 358 >2ZOD-A nrPDB Length = 345 Score = 32.3 bits (72), Expect = 0.97, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 7/64 (10%) Query: 656 VCEKETCQHVRQSLQELPAGSR---VELVNTSCQD--GYQLTGHAYQMCQDAENG--IWF 708 + ++E +++ L +R + L T+C D G+ L GHA+ +C+++ G I+F Sbjct: 194 ILKEEDINEAIENMLALNDKARNLMLSLDATACTDVTGFGLLGHAWNICKNSNIGARIFF 253 Query: 709 KKIP 712 +K+P Sbjct: 254 EKVP 257 >3KYF-A nrPDB Length = 231 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 11/54 (20%) Query: 725 IVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778 I NG+H E F G +++ECD + S+ GH +SGP PQ Sbjct: 66 IENGEH--FRVEGFHDGVRIAWECDHALKI---------SEVDGHRCYSGPLPQ 108 >1Q3X-A nrPDB Length = 328 Score = 31.6 bits (70), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 13/72 (18%) Query: 21 ISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRL--IGEKSLLCITKDKVDGTW- 75 + CG P + +GR+ Y + P VI+YSC TF + + +C + DG W Sbjct: 6 VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVC----EADGFWT 61 Query: 76 ----DKPAPKCE 83 +K P CE Sbjct: 62 SSKGEKSLPVCE 73 >1UL9-A nrPDB Length = 150 Score = 30.8 bits (68), Expect = 3.5, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 397 GTWEPSAPVCEKECQAPPN--ILNGQKEDRHMVRFDPGTSIKYS 438 G W P + E PPN I DR +RFD GTSI Y+ Sbjct: 70 GAWGPEERIPYAEKFRPPNPSITVIDHGDRFQIRFDYGTSIYYN 113 >3TVJ-A nrPDB Length = 86 Score = 30.4 bits (67), Expect = 3.9, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 13/72 (18%) Query: 21 ISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRL--IGEKSLLCITKDKVDGTW- 75 + CG P + +GR+ Y + P VI+YSC TF + + +C DG W Sbjct: 6 VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVC----DADGFWT 61 Query: 76 ----DKPAPKCE 83 +K P CE Sbjct: 62 SSKGEKSLPVCE 73 >5NW4-X nrPDB Length = 417 Score = 30.4 bits (67), Expect = 3.9, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Query: 277 PSPPPI----LNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQK 331 PSPPP L+G I + L ++ S+V + D EE LI +S ++C +D++K Sbjct: 240 PSPPPNVDYPLDGEKILHVLGSIR-DSVVEILFEQDNEEKSVATLILDSLMQCPIDTRK 297 >4ZG8-A nrPDB Length = 426 Score = 29.3 bits (64), Expect = 8.7, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 342 CELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373 C ++ P+PQ+L G +V G D+ YND Sbjct: 367 CGWDQASDPAPNPQVLDGALVGGPDDQDNYND 398 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2GSX-A nrPDB 1245 0.0 1C1Z-A nrPDB 245 9e-65 2OK5-A nrPDB 193 2e-49 5FOB-C nrPDB 193 3e-49 4A5W-B nrPDB 191 1e-48 6H03-D nrPDB 172 9e-43 3ERB-A nrPDB 166 4e-41 1ZJK-A nrPDB 141 1e-33 4FXG-G nrPDB 126 4e-29 4C16-A nrPDB 122 8e-28 4KKD-A nrPDB 115 1e-25 4IGD-A nrPDB 115 1e-25 4J1Y-A nrPDB 108 1e-23 4LOT-A nrPDB 103 5e-22 5UBM-B nrPDB 97 3e-20 Sequences not found previously or not previously below threshold: 1GPZ-A nrPDB 79 1e-14 1Q3X-A nrPDB 76 6e-14 4AQB-A nrPDB 73 8e-13 2QY0-A nrPDB 70 4e-12 3TVJ-A nrPDB 66 9e-11 1ELV-A nrPDB 65 2e-10 4LOS-A nrPDB 55 1e-07 2WCY-A nrPDB 53 5e-07 4F4O-C nrPDB 41 0.002 1MD7-A nrPDB 41 0.003 3OJY-B nrPDB 36 0.069 3NFP-I nrPDB 36 0.090 2RJQ-A nrPDB 36 0.12 1CK7-A nrPDB 36 0.12 4WJG-C nrPDB 35 0.14 5VAI-R nrPDB 35 0.15 1EAK-A nrPDB 35 0.16 1L6J-A nrPDB 34 0.30 3U9U-E nrPDB 34 0.45 4ZXB-E nrPDB 33 0.64 5KQV-E nrPDB 33 0.67 5U8R-A nrPDB 33 0.74 4V2A-A nrPDB 33 0.82 1IGR-A nrPDB 33 0.88 2HR7-A nrPDB 32 1.1 2FON-A nrPDB 32 1.2 3P11-A nrPDB 32 1.6 5FTT-A nrPDB 31 2.6 5O4O-C nrPDB 31 3.6 2JND-A nrPDB 31 3.6 1W0R-A nrPDB 30 5.3 3M0C-C nrPDB 29 9.5 3LTF-A nrPDB 29 9.5 >2GSX-A nrPDB Length = 951 Score = 1245 bits (3220), Expect = 0.0, Method: Composition-based stats. Identities = 951/951 (100%), Positives = 951/951 (100%) Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP Sbjct: 1 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 60 Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP Sbjct: 61 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 120 Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 200 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS Sbjct: 121 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 180 Query: 201 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 260 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG Sbjct: 181 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 240 Query: 261 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE Sbjct: 241 QGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 300 Query: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM Sbjct: 301 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 360 Query: 381 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN Sbjct: 361 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 420 Query: 441 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK Sbjct: 421 PGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 480 Query: 501 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 560 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP Sbjct: 481 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 540 Query: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY Sbjct: 541 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 600 Query: 621 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL 680 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL Sbjct: 601 FYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL 660 Query: 681 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY Sbjct: 661 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 720 Query: 741 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN 800 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN Sbjct: 721 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN 780 Query: 801 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 860 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG Sbjct: 781 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 840 Query: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG Sbjct: 841 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 900 Query: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 971 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR Sbjct: 901 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 951 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 246/732 (33%), Positives = 333/732 (45%), Gaps = 61/732 (8%) Query: 16 PGVLGISCGSPPPILNGRISYYS-TPIAVGTVIRYSCSG------TFRLIGEKSLLCITK 68 P I C SPPPILNGR S ++ G+++ Y+C F LIGE +L C Sbjct: 249 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 308 Query: 69 DKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGN 127 + GTW PAP+CE CP P + G + G Y + D+V FAC F++ G+ Sbjct: 309 SQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS 368 Query: 128 KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187 K + C A W P+ EC A P I NG ++ PG S+ YSC GY Sbjct: 369 KQIRCNAQGTWEPSAPVCE-----KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 423 Query: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247 +LVGE+ I C S G W+ P C+ A C++ GR + +P V N C EGY+ Sbjct: 424 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGR---QLLTKPQHQFVRPDVNSSCGEGYK 480 Query: 248 LQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDP 307 L G C G + ++ +C+EI CP PP I NG H G+SL + YG+ VTYTC+P Sbjct: 481 LSGSVYQECQ--GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNP 538 Query: 308 DPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKD 367 PE GV F LIGEST+RCT + Q+ GTWSGPAP C+LS AVQC H I G +SG++ Sbjct: 539 GPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEA 598 Query: 368 RYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMV 427 Y YNDTV F C GFTLKGS QIRC A TW+P PVCEKE ++ +E Sbjct: 599 PYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE--TCQHVRQSLQELPAGS 656 Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCT--SEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485 R + + SC GY L G C G+W +P CKV C ++ +H Sbjct: 657 RVEL---VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPP--PVIVNGKHT 711 Query: 486 -------FVRPDVNSSCGEGYKLSGSVYQEC----QGTIPWFMEIRLC----KEITCPPP 530 +V+ C +G+ L G +C +G W C CP P Sbjct: 712 GMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP 771 Query: 531 PVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPA 590 + +G + + + V CNPG F + G IRC TW Sbjct: 772 -EVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRC----HTDNTWVPGV 820 Query: 591 PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTW 650 P C NG G A + ++ + C G+ L G + + C + TW Sbjct: 821 PTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTW 880 Query: 651 DPEIPVCEKETCQHV------RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAEN 704 P C++ C ++ L+ +V C+DGY L G CQ Sbjct: 881 SQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQ 940 Query: 705 GIWFKKIPLCKV 716 W + +C+ Sbjct: 941 --WNPPLAVCRS 950 Score = 350 bits (897), Expect = 2e-96, Method: Composition-based stats. Identities = 222/937 (23%), Positives = 354/937 (37%), Gaps = 154/937 (16%) Query: 152 LECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC----LSSGKWSAVP 207 + C + P I NG S IA G + YSC + L+GEK + C G W Sbjct: 1 ISCGSPPPILNGRI-SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPA 59 Query: 208 PTCEE----ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGV 263 P CE + C K++ R G + F C + + G S C Sbjct: 60 PKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 119 Query: 264 AWTKMPVCEEIF---CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320 T++P C +F CP+ P I NG H ++ +++ G VTY+C+ ++L+GE Sbjct: 120 P-TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCES------GYLLVGE 172 Query: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380 + C +G WS P CE + +C V + T F C Sbjct: 173 KIINCL----SSGKWSAVPPTCEEA----RCKSLGRFPNGKVK-EPPILRVGVTANFFCD 223 Query: 381 FGFTLKGSKQIRCNAQGT---WEPSAPVCEKE-CQAPPNILNGQKEDRHMVRFDPGTSIK 436 G+ L+G RC G W PVCE+ C +PP ILNG+ + G+ + Sbjct: 224 EGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVT 282 Query: 437 YSCNP------GYVLVGEESIQC----TSEGVWTPPVPQCK----VAACEAT----GRQL 478 Y+C+P ++L+GE +++C G W+ P P+C+ C GR + Sbjct: 283 YTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV 342 Query: 479 LTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAH 538 + V +C G+ L GS C W +C++ C PP I NG Sbjct: 343 SGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQK 401 Query: 539 TGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL 598 + F GT++ Y+CNPG + L+GE +I+CTS G W+ P P CK++ Sbjct: 402 EDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTS----EGVWTPPVPQCKVAAC 451 Query: 599 AVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCE 658 A G ++ K F V C G+ L GS C+ W EI +C+ Sbjct: 452 E--------ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCK 503 Query: 659 KETCQHVRQSLQELPAGSRVE------LVNTSCQDG------YQLTGHAYQMC--QDAEN 704 + TC GS +E V +C G + L G + C D E Sbjct: 504 EITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 563 Query: 705 GIWFKKIPLCKV----IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 760 G W PLCK+ + C I NG + Y + V+++C GF L G ++ Sbjct: 564 GTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQI 622 Query: 761 QCRSDSK----------------------------------------------------- 767 +C++D+ Sbjct: 623 RCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 682 Query: 768 GHGSWSGPSPQCLRSPPVTRC-PNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 826 +G W P C V C P P + +G + + + V +C+ GF + G + Sbjct: 683 ENGIWFKKIPLC----KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK 738 Query: 827 VIRCHTD----NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882 ++C +D +W P C++ + P P+ +G + +S + C+ Sbjct: 739 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNP 798 Query: 883 GYLLVGEALLLCTHEGTWSQPAPHCKE---VNCSSPADMDGIQKGLEPRKMYQYGAVVTL 939 G+++ G ++ C + TW P C + + C P + G + Sbjct: 799 GFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 858 Query: 940 ECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPV 976 C+ GY+L G C + W+ P C+ + + Sbjct: 859 SCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP 895 Score = 190 bits (483), Expect = 2e-48, Method: Composition-based stats. Identities = 114/445 (25%), Positives = 161/445 (36%), Gaps = 53/445 (11%) Query: 600 VQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC----KADNTWDPEIP 655 + C +IS P + + C F L G + C K D TWD P Sbjct: 1 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 60 Query: 656 VC----EKETCQHVRQSLQELPAGS----RVELVNTSCQDGYQLTGHAYQMCQDAENGIW 707 C + +C GS + V +C+ + + G+ CQ N +W Sbjct: 61 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQA--NNMW 118 Query: 708 FKK-IPLCKVIH---CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCR 763 +P C + C P+I NG HT + G V+Y C+ G+ L+GEK + C Sbjct: 119 GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 178 Query: 764 SDSKGHGSWSGPSPQCL--RSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFI 821 S G WS P C R + R PN +VK C+ G+ Sbjct: 179 SS----GKWSAVPPTCEEARCKSLGRFPNGKVKE-------PPILRVGVTANFFCDEGYR 227 Query: 822 MNGSRVIRCHTDNT---WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 878 + G RC W +P C + I CP PP NG H G ++A S G + Y Sbjct: 228 LQGPPSSRCVIAGQGVAWTK-MPVCEE---IFCPSPPPILNGRHIGNSLANVSYGSIVTY 283 Query: 879 SCDQ------GYLLVGEALLLCTHE----GTWSQPAPHC----KEVNCSSPADMDGIQKG 924 +CD ++L+GE+ L CT + GTWS PAP C V C P + G Sbjct: 284 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVS 343 Query: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGL 984 + + Y Y V C G+ L+GS Q +C + W P VC AP Sbjct: 344 GQKDR-YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKE 402 Query: 985 ILLTFLIVITLYVISKHRARNYYTD 1009 + Sbjct: 403 DRHMVRFDPGTSIKYSCNPGYVLVG 427 >1C1Z-A nrPDB Length = 326 Score = 245 bits (624), Expect = 9e-65, Method: Composition-based stats. Identities = 77/301 (25%), Positives = 115/301 (38%), Gaps = 31/301 (10%) Query: 90 SCPEPI-VPGGYKIRGSTPYRHGDSVTFACKTNF-SMNGNKSVWCQANNMWGPTRLPTCV 147 +CP+P +P + T Y G+ +T++CK + S G + C +W P C Sbjct: 3 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW-PINTLKCT 61 Query: 148 SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP 207 P CP ++ NG + + ++++SC +G+ L G C GKWS Sbjct: 62 ---PRVCPFAGILENG---AVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPEL 115 Query: 208 PTCEEARCKSLGR--FPNGKVKEPPILRVG---VTANFFCDEGYRLQGPPSSRCVIAGQG 262 P C C F +V +P TA F C + + G + C G Sbjct: 116 PVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGN- 174 Query: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322 WTK+P C E+ CP P NG + + Y T+ C + L G Sbjct: 175 --WTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHD------GYSLDGPEE 226 Query: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQ---KDRYTYNDTVIFAC 379 + CT K G WS P C+ S + +G V Q K+ + D V F C Sbjct: 227 IECT----KLGNWSA-MPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC 281 Query: 380 M 380 Sbjct: 282 K 282 Score = 220 bits (559), Expect = 3e-57, Method: Composition-based stats. Identities = 72/295 (24%), Positives = 110/295 (37%), Gaps = 28/295 (9%) Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS-KQIRCNAQGTWEPSAPVCE- 407 CP P L V K Y + + ++C G+ +G ++ C G W + C Sbjct: 3 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 62 Query: 408 KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467 + C + NG F+ +I +SCN G+ L G +S +CT EG W+P +P C Sbjct: 63 RVCPFAGILENGA---VRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCA 119 Query: 468 VAACEATGRQLLTK--------PQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEI 519 C + R C + + G+ C W ++ Sbjct: 120 PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW-TKL 178 Query: 520 RLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579 C+E+ CP P NG + Y T+ C+ G +SL G I CT Sbjct: 179 PECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDG------YSLDGPEEIECT-- 230 Query: 580 DQERGTWSGPAPLCKLS--LLAVQCSHVHIANGYKISG-KEAPYFYNDTVTFKCY 631 + G WS P CK S L + + V+ KI + + D V+F C Sbjct: 231 --KLGNWSA-MPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 282 Score = 203 bits (517), Expect = 2e-52, Method: Composition-based stats. Identities = 53/245 (21%), Positives = 94/245 (38%), Gaps = 13/245 (5%) Query: 733 MMAENFLYGNEVSYECDQGFYLLG-EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP 791 + + G E++Y C G+ G +K C G W + +C +P V CP Sbjct: 17 PLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLT----GLWPINTLKC--TPRV--CPFA 68 Query: 792 EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 851 + + ++ + + + + CN GF +NG+ +C + W P +P C Sbjct: 69 GILENGAVR--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPP 126 Query: 852 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 911 P + + ++ C + + G + CT G W++ P C+EV Sbjct: 127 SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTK-LPECREVK 185 Query: 912 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR 971 C P+ D + Y T C DGY L+G + +C W+ + C++ Sbjct: 186 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKAS 244 Query: 972 SLAPV 976 PV Sbjct: 245 CKLPV 249 Score = 139 bits (350), Expect = 6e-33, Method: Composition-based stats. Identities = 74/335 (22%), Positives = 116/335 (34%), Gaps = 42/335 (12%) Query: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585 TCP P + + G +TY+C PG G C G Sbjct: 3 TCPKPDDLPFSTVV-PLKTFYEPGEEITYSCKPGYVSRG-----GMRKFIC----PLTGL 52 Query: 586 WSGPAPLCKLSLLAVQCSHVHIA-NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644 W C + C I NG + Y +T++F C +GF L G+ +C Sbjct: 53 WPINTLKCTPRV----CPFAGILENGAVRY---TTFEYPNTISFSCNTGFYLNGADSAKC 105 Query: 645 KADNTWDPEIPVCE------KETCQHVRQSLQELPAGSRVELVNTS---CQDGYQLTGHA 695 + W PE+PVC + + AG+ +T+ C + + G+ Sbjct: 106 TEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGND 165 Query: 696 YQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL 755 C +G W K+P C+ + C P NG Y ++ ++ C G+ L Sbjct: 166 TITC--TTHGNW-TKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD 222 Query: 756 GEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHG---YKLNKTHSAYSHNDIV 812 G ++++C G+WS P C S + V G K + H D V Sbjct: 223 GPEEIEC----TKLGNWSA-MPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKV 277 Query: 813 YVDC-NPGFIMNGSRVIRCHTDNTWVPGVPTCIKK 846 C N + + +C VP C K+ Sbjct: 278 SFFCKNKEKKCSYTEDAQCIDG---TIEVPKCFKE 309 Score = 114 bits (285), Expect = 2e-25, Method: Composition-based stats. Identities = 72/334 (21%), Positives = 111/334 (33%), Gaps = 32/334 (9%) Query: 20 GISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE-KSLLCITKDKVDGTWDKP 78 G +C P + + T G I YSC + G + +C G W Sbjct: 1 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLT----GLWPIN 56 Query: 79 APKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMW 138 KC CP + +R +T ++++F+C T F +NG S C W Sbjct: 57 TLKC----TPRVCPFAGILENGAVRYTTFEYP-NTISFSCNTGFYLNGADSAKCTEEGKW 111 Query: 139 GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 198 P LP C + + + + + C + + G I C Sbjct: 112 SPE-LPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCT 170 Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKEP--PILRVGVTANFFCDEGYRLQGPPSSRC 256 + G W P C E +C R NG V P P L A F C +GY L GP C Sbjct: 171 THGNW-TKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIEC 229 Query: 257 VIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNS-------LANVSYGSIVTYTCDPDP 309 G W+ MP C+ C P + G + +G V++ C + Sbjct: 230 TKLGN---WSAMPSCKAS-CKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC-KNK 284 Query: 310 EEGVNFILIGE------STLRCTVDSQKTGTWSG 337 E+ ++ + +C + W Sbjct: 285 EKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKT 318 Score = 76.5 bits (186), Expect = 6e-14, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 5/119 (4%) Query: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL-LLCTHEGTWSQPAPHCKE 909 CP P P + PG I YSC GY+ G +C G W C Sbjct: 4 CPKPDDLPFST-VVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 62 Query: 910 VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968 C ++ ++Y ++ C G+ L G+ ++C + +W+P L VC Sbjct: 63 RVCPFAGILENGAVRYT---TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVC 118 Score = 38.0 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 40/114 (35%), Gaps = 20/114 (17%) Query: 16 PGVLGISCGSPPPILNGRISYYSTP-IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74 P + C P NG ++Y + P + + C + L G + + C G Sbjct: 179 PECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKL----GN 234 Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG---------STPYRHGDSVTFACK 119 W P C+ +SC P+ +G HGD V+F CK Sbjct: 235 WSA-MPSCK-----ASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 282 >2OK5-A nrPDB Length = 752 Score = 193 bits (491), Expect = 2e-49, Method: Composition-based stats. Identities = 57/272 (20%), Positives = 93/272 (34%), Gaps = 31/272 (11%) Query: 447 GEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSS--CGEGYKLSGS 504 G W+ PQ +C G + + + ++ C G+ Sbjct: 1 GSHHHHHHGSTPWSLARPQ---GSCSLEGVE-IKGGSFRLLQEGQALEYVCPSGFYPYPV 56 Query: 505 VYQECQGTIPWFM---------EIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYT 555 + C+ T W C+ I CP P NG + S + +++ Sbjct: 57 QTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRS-PYYNVSDEISFH 115 Query: 556 CNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISG 615 C G ++L G + C N G WSG +C A CS+ I G + G Sbjct: 116 CYDG------YTLRGSANRTCQVN----GRWSGQTAICDNG--AGYCSNPGIPIGTRKVG 163 Query: 616 KEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAG 675 + Y D+VT+ C G TL+GS + C+ +W P C+ Q + E Sbjct: 164 SQ--YRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLS 221 Query: 676 SRVELVN-TSCQDGYQLTGHAYQMCQDAENGI 706 S E + +DG+ + +G Sbjct: 222 SLTETIEGVDAEDGHGPGEQQKRKIVLDPSGS 253 Score = 186 bits (471), Expect = 5e-47, Method: Composition-based stats. Identities = 45/174 (25%), Positives = 62/174 (35%), Gaps = 13/174 (7%) Query: 741 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP-----VTRCPNPEVKH 795 G + Y C GFY + CRS GSWS Q ++ CP P Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRST----GSWSTLKTQDQKTVRKAECRAIHCPRPHDFE 95 Query: 796 GYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP 855 + Y+ +D + C G+ + GS C + W C A G P Sbjct: 96 NGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA--GYCSNP 153 Query: 856 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKE 909 P G G+ R S+ Y C +G L G C G+WS P C++ Sbjct: 154 GIPIGTRKVGSQYRLED--SVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 205 Score = 170 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 45/183 (24%), Positives = 68/183 (37%), Gaps = 23/183 (12%) Query: 173 IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---------CEEARCKSLGRFPN 223 + G ++ Y C SG+ + C S+G WS + C C F N Sbjct: 37 LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFEN 96 Query: 224 GKV-KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPI 282 G+ P V +F C +GY L+G + C + G+ T + +C +P Sbjct: 97 GEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP 156 Query: 283 LNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342 + R +G + VTY C L G C Q+ G+WSG P C Sbjct: 157 IGTRKVG---SQYRLEDSVTYHCSR------GLTLRGSQRRTC----QEGGSWSGTEPSC 203 Query: 343 ELS 345 + S Sbjct: 204 QDS 206 Score = 163 bits (413), Expect = 3e-40, Method: Composition-based stats. Identities = 44/194 (22%), Positives = 67/194 (34%), Gaps = 19/194 (9%) Query: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340 + G S + G + Y C F T C + TG+WS Sbjct: 23 SLEGVEIKGGSFRLLQEGQALEYVC------PSGFYPYPVQTRTC----RSTGSWSTLKT 72 Query: 341 RCE-----LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395 + + A+ CP P + Y +D + F C G+TL+GS C Sbjct: 73 QDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQV 132 Query: 396 QGTWEPSAPVCEKECQAP--PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453 G W +C+ P I G ++ R + S+ Y C+ G L G + C Sbjct: 133 NGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLE--DSVTYHCSRGLTLRGSQRRTC 190 Query: 454 TSEGVWTPPVPQCK 467 G W+ P C+ Sbjct: 191 QEGGSWSGTEPSCQ 204 Score = 135 bits (338), Expect = 1e-31, Method: Composition-based stats. Identities = 35/173 (20%), Positives = 59/173 (34%), Gaps = 13/173 (7%) Query: 852 PPPPKTPNGNHT-GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQ-------- 902 P + G GG+ G ++ Y C G+ C G+WS Sbjct: 18 PQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKT 77 Query: 903 -PAPHCKEVNCSSPADMDGIQKGLEPR-KMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQ 960 C+ ++C P D + + PR Y ++ C DGY L GS CQ + + Sbjct: 78 VRKAECRAIHCPRPHDFENGE--YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGR 135 Query: 961 WNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQK 1013 W+ A+C + + GI G + + V + ++ Sbjct: 136 WSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRR 188 Score = 120 bits (299), Expect = 5e-27, Method: Composition-based stats. Identities = 48/215 (22%), Positives = 77/215 (35%), Gaps = 34/215 (15%) Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458 W + P + + + R G +++Y C G+ ++ C S G Sbjct: 13 WSLARP---QGSCSLEGVEIKGGSFR---LLQEGQALEYVCPSGFYPYPVQTRTCRSTGS 66 Query: 459 WTPPVPQCKVAACEATGRQLLTKPQHQF-------------VRPDVNSSCGEGYKLSGSV 505 W+ Q + +A R + H F V +++ C +GY L GS Sbjct: 67 WSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSA 126 Query: 506 YQECQGTIPWFMEIRLCK--EITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERG 563 + CQ W + +C C P + GS + +VTY C+ G Sbjct: 127 NRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQ---YRLEDSVTYHCSRGL--- 180 Query: 564 VEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL 598 +L G C QE G+WSG P C+ S + Sbjct: 181 ---TLRGSQRRTC----QEGGSWSGTEPSCQDSFM 208 Score = 119 bits (298), Expect = 6e-27, Method: Composition-based stats. Identities = 47/230 (20%), Positives = 74/230 (32%), Gaps = 25/230 (10%) Query: 638 GSSQIRCKADNTWDPEIPVCEKETCQHVRQSL--QELPAGSRVELVNTSCQDGYQLTGHA 695 GS W P + +C + + + C G+ Sbjct: 1 GSHHHHHHGSTPWSLARP---QGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQ 57 Query: 696 YQMCQDAENGIWFK---------KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 746 + C+ G W + C+ IHC P NG++ + + +E+S+ Sbjct: 58 TRTCRST--GSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY-WPRSPYYNVSDEISF 114 Query: 747 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAY 806 C G+ L G C+ + G WSG + C C NP + G K S Y Sbjct: 115 HCYDGYTLRGSANRTCQVN----GRWSGQTAICDNG--AGYCSNPGIPIG--TRKVGSQY 166 Query: 807 SHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPK 856 D V C+ G + GS+ C +W P+C P Sbjct: 167 RLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVA 216 Score = 118 bits (296), Expect = 1e-26, Method: Composition-based stats. Identities = 41/175 (23%), Positives = 60/175 (34%), Gaps = 17/175 (9%) Query: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDK-PAPKCEYFNKYSS----CPEP-IVP 97 G + Y C F ++ C + G+W + K CP P Sbjct: 40 GQALEYVCPSGFYPYPVQTRTC----RSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFE 95 Query: 98 GGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPAL 157 G S Y D ++F C +++ G+ + CQ N W P + Sbjct: 96 NGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI 155 Query: 158 PMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCE 211 P+ + VGS SVTY C G L G + C G WS P+C+ Sbjct: 156 PI------GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 204 Score = 110 bits (273), Expect = 5e-24, Method: Composition-based stats. Identities = 42/204 (20%), Positives = 65/204 (31%), Gaps = 25/204 (12%) Query: 335 WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCN 394 WS P+ S V+ ++G ++ + + C GF + C Sbjct: 13 WSLARPQGSCSLEGVE------IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCR 62 Query: 395 AQGTWE---------PSAPVCEKE-CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYV 444 + G+W C C P + NG + ++ I + C GY Sbjct: 63 STGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG-EYWPRSPYYNVSDEISFHCYDGYT 121 Query: 445 LVGEESIQCTSEGVWTPPVPQCKVAA--CEATGRQLLTKPQHQFVR--PDVNSSCGEGYK 500 L G + C G W+ C A C G + T+ R V C G Sbjct: 122 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLT 181 Query: 501 LSGSVYQECQGTIPWFMEIRLCKE 524 L GS + CQ W C++ Sbjct: 182 LRGSQRRTCQEGGSWSGTEPSCQD 205 Score = 106 bits (265), Expect = 4e-23, Method: Composition-based stats. Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 8/138 (5%) Query: 18 VLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDK 77 I C P NG S V I + C + L G + C +V+G W Sbjct: 83 CRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC----QVNGRWSG 138 Query: 78 PAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137 C+ N C P +P G + GS YR DSVT+ C ++ G++ CQ Sbjct: 139 QTAICD--NGAGYCSNPGIPIGTRKVGS-QYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS 195 Query: 138 WGPTRLPTCVSVFPLECP 155 W T P+C F + P Sbjct: 196 WSGTE-PSCQDSFMYDTP 212 Score = 97.3 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 48/208 (23%), Positives = 66/208 (31%), Gaps = 22/208 (10%) Query: 772 WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 831 WS PQ C V+ + + C GF + C Sbjct: 13 WSLARPQ-------GSCSLEGVEIKGGSFRL---LQEGQALEYVCPSGFYPYPVQTRTCR 62 Query: 832 TDNTWVP---GVPTCIKKA---FIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 885 + +W ++KA I CP P NG + ++ I + C GY Sbjct: 63 STGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY-WPRSPYYNVSDEISFHCYDGYT 121 Query: 886 LVGEALLLCTHEGTWSQPAPHCKEVN--CSSPADMDGIQKGLEPRKMYQYGAVVTLECED 943 L G A C G WS C CS+P G +K Y+ VT C Sbjct: 122 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV---GSQYRLEDSVTYHCSR 178 Query: 944 GYMLEGSPQSQCQSDHQWNPPLAVCRSR 971 G L GS + CQ W+ C+ Sbjct: 179 GLTLRGSQRRTCQEGGSWSGTEPSCQDS 206 >5FOB-C nrPDB Length = 245 Score = 193 bits (491), Expect = 3e-49, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 112/239 (46%), Gaps = 20/239 (8%) Query: 172 SIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPI 231 + G ++ Y C GY I +G + C + RC S NG + + Sbjct: 25 NYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGHLDIGGV 84 Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWT-KMPVCEEIFCPSPPPILNGRHIG 289 G + + C+ GY L G S C + G + W K P+CE + C PP I NGRH G Sbjct: 85 -DFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHNG 143 Query: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349 + GS+VTY+C+ + LIG S + C G WS P P C++ V Sbjct: 144 YNDFYTD-GSVVTYSCNS------GYSLIGNSGVLC-----SGGEWSNP-PTCQI----V 186 Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408 +CPHP IL G + SG K Y+YND V F C +G+ L GS C+ TW+P P C + Sbjct: 187 KCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 245 Score = 187 bits (473), Expect = 3e-47, Method: Composition-based stats. Identities = 84/248 (33%), Positives = 115/248 (46%), Gaps = 31/248 (12%) Query: 422 EDRHMVRFDPGTSIKYSCNPGYVL--VGEESIQCTSEGVWTPPVPQCKVAACEATGRQLL 479 E ++ G +I+Y C PGY +G +CT G WT QC C + + + Sbjct: 19 ETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTG-WTL-FNQCIKRRCPSP--RDI 74 Query: 480 TKPQHQFVRPD----VNSSCGEGYKLSGSVYQEC----QGTIPWFMEIRLCKEITCPPPP 531 D + SC GY L G C G++ W + +C+ + C PP Sbjct: 75 DNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPP 134 Query: 532 VIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAP 591 I NG H G + + + G+ VTY+CN G +SLIG S + C+ G WS P P Sbjct: 135 SISNGRHNGYN-DFYTDGSVVTYSCNSG------YSLIGNSGVLCSG-----GEWSNP-P 181 Query: 592 LCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD 651 C++ V+C H I NGY SG + Y YND V F C G+ L GSS C NTW Sbjct: 182 TCQI----VKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQ 237 Query: 652 PEIPVCEK 659 PE+P C + Sbjct: 238 PELPKCVR 245 Score = 162 bits (410), Expect = 6e-40, Method: Composition-based stats. Identities = 67/241 (27%), Positives = 104/241 (43%), Gaps = 20/241 (8%) Query: 612 KISGKEAPYFYNDTVTFKCYSGF--TLKGSSQIRCKADNTWDPEIPVCEKETCQ---HVR 666 + A Y DT+ + C G+ G +C W C K C + Sbjct: 18 VETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTG-WT-LFNQCIKRRCPSPRDID 75 Query: 667 QSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENG--IWFKKIPLCKVIHCHPPPV 724 ++ + SC GY L G C+ G +W K P+C+ + C PP Sbjct: 76 NGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPS 135 Query: 725 IVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP 784 I NG+H G + + G+ V+Y C+ G+ L+G + C G WS P P C Sbjct: 136 ISNGRHNGY-NDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-----GEWSNP-PTCQ---- 184 Query: 785 VTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCI 844 + +CP+P + +GY + +YS+ND V C G+ ++GS C NTW P +P C+ Sbjct: 185 IVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCV 244 Query: 845 K 845 + Sbjct: 245 R 245 Score = 156 bits (395), Expect = 3e-38, Method: Composition-based stats. Identities = 65/228 (28%), Positives = 92/228 (40%), Gaps = 23/228 (10%) Query: 89 SSCPEPIVPGGYKIRGSTP------YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTR 142 S C P P K + S Y GD++ + C + ++ + G T Sbjct: 1 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTL 59 Query: 143 LPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL--SS 200 C+ CP+ I NGH ++G + G S+TYSC SGY L+GE C S+ Sbjct: 60 FNQCIK---RRCPSPRDIDNGHL---DIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGST 113 Query: 201 GK--WSAVPPTCEEARCKSLGRFPNGKVK-EPPILRVGVTANFFCDEGYRLQGPPSSRCV 257 G W+ P CE +C+ NG+ G + C+ GY L G C Sbjct: 114 GSMVWNPKAPICESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC- 172 Query: 258 IAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTC 305 G W+ P C+ + CP P ILNG + SY V +TC Sbjct: 173 ---SGGEWSNPPTCQIVKCPHP-TILNGYLSSGFKRSYSYNDNVDFTC 216 Score = 143 bits (359), Expect = 5e-34, Method: Composition-based stats. Identities = 70/259 (27%), Positives = 103/259 (39%), Gaps = 27/259 (10%) Query: 719 CHPPPVIVNGK----HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSG 774 C P +N K N+ G+ + Y C G+ + + G ++ Sbjct: 3 CTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFN- 61 Query: 775 PSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC---- 830 QC++ RCP+P L+ + + CN G+ + G C Sbjct: 62 ---QCIK----RRCPSPRDIDNGHLDIGGVDF--GSSITYSCNSGYYLIGEYKSYCKLGS 112 Query: 831 HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEA 890 W P P C + C PP NG H G N ++ G + YSC+ GY L+G + Sbjct: 113 TGSMVWNPKAPICE---SVKCQLPPSISNGRHNGYN-DFYTDGSVVTYSCNSGYSLIGNS 168 Query: 891 LLLCTHEGTWSQPAPHCKEVNCSSPADMDG-IQKGLEPRKMYQYGAVVTLECEDGYMLEG 949 +LC G WS P P C+ V C P ++G + G ++ Y Y V C+ GY L G Sbjct: 169 GVLC-SGGEWSNP-PTCQIVKCPHPTILNGYLSSGF--KRSYSYNDNVDFTCKYGYKLSG 224 Query: 950 SPQSQCQSDHQWNPPLAVC 968 S S C + W P L C Sbjct: 225 SSSSTCSPGNTWQPELPKC 243 Score = 115 bits (286), Expect = 2e-25, Method: Composition-based stats. Identities = 76/260 (29%), Positives = 110/260 (42%), Gaps = 27/260 (10%) Query: 215 CKSLGRFPNGKVKEP------PILRVGVTANFFCDEGYRLQ--GPPSSRCVIAGQGVAWT 266 C R N K K +G T + C GYR Q GP ++C G WT Sbjct: 3 CTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCT----GTGWT 58 Query: 267 KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326 C + CPSP I NG + V +GS +TY+C+ + LIGE C Sbjct: 59 LFNQCIKRRCPSPRDIDNGHL---DIGGVDFGSSITYSCNS------GYYLIGEYKSYCK 109 Query: 327 VDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK 386 + S + W+ AP CE +V+C P + +G D YT V ++C G++L Sbjct: 110 LGSTGSMVWNPKAPICE----SVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLI 165 Query: 387 GSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV 446 G+ + C + G W P C+ P ILNG + ++ ++C GY L Sbjct: 166 GNSGVLC-SGGEWSN-PPTCQIVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLS 223 Query: 447 GEESIQCTSEGVWTPPVPQC 466 G S C+ W P +P+C Sbjct: 224 GSSSSTCSPGNTWQPELPKC 243 Score = 104 bits (259), Expect = 2e-22, Method: Composition-based stats. Identities = 47/134 (35%), Positives = 63/134 (47%), Gaps = 12/134 (8%) Query: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74 AP + C PP I NGR + Y+ G+V+ YSC+ + LIG +LC G Sbjct: 122 APICESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGE 176 Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133 W P P C+ CP P + GY G Y + D+V F CK + ++G+ S C Sbjct: 177 WSNP-PTCQIVK----CPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCS 231 Query: 134 ANNMWGPTRLPTCV 147 N W P LP CV Sbjct: 232 PGNTWQPE-LPKCV 244 Score = 88.8 bits (218), Expect = 1e-17, Method: Composition-based stats. Identities = 54/194 (27%), Positives = 80/194 (41%), Gaps = 14/194 (7%) Query: 18 VLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDK 77 + C SP I NG + + G+ I YSC+ + LIGE C W+ Sbjct: 63 CIKRRCPSPRDIDNGHLD--IGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNP 120 Query: 78 PAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQANN 136 AP CE C P + G + Y G VT++C + +S+ GN V C + Sbjct: 121 KAPICESVK----CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGG 175 Query: 137 MWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196 W PTC ++CP ++ NG+ +S S + +V ++C+ GY L G Sbjct: 176 EWS--NPPTCQI---VKCPHPTIL-NGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSST 229 Query: 197 CLSSGKWSAVPPTC 210 C W P C Sbjct: 230 CSPGNTWQPELPKC 243 Score = 79.6 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 90/250 (36%), Gaps = 17/250 (6%) Query: 24 GSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCE 83 N + + +G I Y C +R K + K GT +C Sbjct: 9 PINMKFKNSVETDANANYNIGDTIEYLCLPGYR----KQKMGPIYAKCTGTGWTLFNQC- 63 Query: 84 YFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRL 143 CP P + G S+T++C + + + G +C+ + Sbjct: 64 ---IKRRCPSPRDIDNGHLDIG-GVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWN 119 Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203 P ++C P I NG H N G VTYSC SGY L+G + C S G+W Sbjct: 120 PKAPICESVKCQLPPSISNGRHNGYN-DFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEW 177 Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEPP--ILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261 S PPTC+ +C NG + +F C GY+L G SS C Sbjct: 178 SN-PPTCQIVKCPHPTIL-NGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNT 235 Query: 262 GVAWTKMPVC 271 ++P C Sbjct: 236 W--QPELPKC 243 Score = 52.6 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 39/138 (28%), Positives = 53/138 (38%), Gaps = 13/138 (9%) Query: 852 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY--LLVGEALLLCTHEGTWSQPAPHCKE 909 P K N T N A ++ G +I Y C GY +G CT G W+ C + Sbjct: 9 PINMKFKNSVETDAN-ANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTG-WTLFN-QCIK 65 Query: 910 VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPL 965 C SP D+D + +G+ +T C GY L G +S C WNP Sbjct: 66 RRCPSPRDIDNGHLDI---GGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKA 122 Query: 966 AVCRSRSLAPVLCGIAAG 983 +C S I+ G Sbjct: 123 PICESVKCQLP-PSISNG 139 >4A5W-B nrPDB Length = 913 Score = 191 bits (485), Expect = 1e-48, Method: Composition-based stats. Identities = 55/288 (19%), Positives = 90/288 (31%), Gaps = 31/288 (10%) Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEI 274 C+ NG+ + V + E Q P + GQ W+ C+ Sbjct: 500 CQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDAT 559 Query: 275 F-------CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV 327 + C +P P G+ + EE F ++ + C Sbjct: 560 YKRSRTRECNNPAPQRGGKRCEG---------------EKRQEEDCTFSIMENNGQPCIN 604 Query: 328 DSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387 D ++ P E+ + CP P + +K Y + V +C+ GF G Sbjct: 605 DDEEMKEVDLP----EIEADS-GCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVG 659 Query: 388 SKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVG 447 + RC GTW C++ P + + G SI+ +C G+V+ G Sbjct: 660 YQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAG 719 Query: 448 EESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSC 495 C WTPP+ + K Q + S C Sbjct: 720 PSRYTCQGN-SWTPPISNSLTCEKD---TLTKLKGHCQLGQKQSGSEC 763 Score = 151 bits (381), Expect = 1e-36, Method: Composition-based stats. Identities = 58/255 (22%), Positives = 88/255 (34%), Gaps = 24/255 (9%) Query: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY----LLGEKKLQCRSDSKGHGSWSG 774 C P NG+ T L G E C G Y + + G WS Sbjct: 500 CQCAPCPNNGRPT-------LSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSS 552 Query: 775 PSPQCL--RSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT 832 S + C NP + G K + DC + N + C Sbjct: 553 WSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEE------DCTFSIMENNGQP--CIN 604 Query: 833 DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALL 892 D+ + V +A GCP P NG + G + SC G+ VG Sbjct: 605 DDEEMKEVDLPEIEADSGCPQPVPPENG-FIRNEKQLYLVGEDVEISCLTGFETVGYQYF 663 Query: 893 LCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQ 952 C +GTW Q C+ C P + + +++Y+ G + L C G+++ G + Sbjct: 664 RCLPDGTWRQGDVECQRTECIKPVVQEVLTIT-PFQRLYRIGESIELTCPKGFVVAGPSR 722 Query: 953 SQCQSDHQWNPPLAV 967 CQ + W PP++ Sbjct: 723 YTCQGN-SWTPPISN 736 Score = 64.5 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 52/273 (19%), Positives = 80/273 (29%), Gaps = 49/273 (17%) Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFM 517 + C+ A C GR L+ + V GE + Y+ W Sbjct: 492 EYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTY--GENCEKQSPDYKSNAVDGQW-- 547 Query: 518 EIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCN-----------PGPERGVE- 565 G + S D Y + T CN G +R E Sbjct: 548 ------------------GCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEED 589 Query: 566 --FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYN 623 FS++ + C ++D+E P C I ++ Y Sbjct: 590 CTFSIMENNGQPCINDDEEMKEVDLPEIEADSG-----CPQPVPPENGFIRNEKQLYLVG 644 Query: 624 DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVR-QSLQELPAGSR----V 678 + V C +GF G RC D TW C++ C Q + + R Sbjct: 645 EDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIG 704 Query: 679 ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKI 711 E + +C G+ + G + CQ W I Sbjct: 705 ESIELTCPKGFVVAGPSRYTCQGN---SWTPPI 734 Score = 61.5 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 36/127 (28%), Positives = 51/127 (40%), Gaps = 12/127 (9%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82 C P P NG I VG + SC F +G + C+ DGTW + +C Sbjct: 623 CPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCL----PDGTWRQGDVEC 678 Query: 83 EYFNKYSSCPEPIVPGGYKI-RGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP- 140 + + C +P+V I YR G+S+ C F + G CQ N+ W P Sbjct: 679 Q----RTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGNS-WTPP 733 Query: 141 -TRLPTC 146 + TC Sbjct: 734 ISNSLTC 740 Score = 59.9 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 31/124 (25%), Positives = 46/124 (37%), Gaps = 7/124 (5%) Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213 CP NG +E G V SC +G+ VG + CL G W C+ Sbjct: 623 CPQPVPPENGFIRNEKQ-LYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRT 681 Query: 214 RCKSLGRFPNGKV-KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCE 272 C + + R+G + C +G+ + GP C QG +WT P+ Sbjct: 682 ECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTC----QGNSWTP-PISN 736 Query: 273 EIFC 276 + C Sbjct: 737 SLTC 740 Score = 56.8 bits (135), Expect = 5e-08, Method: Composition-based stats. Identities = 41/220 (18%), Positives = 66/220 (30%), Gaps = 15/220 (6%) Query: 54 TFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGD 112 TF ++ CI D+ D P + + S CP+P+ P IR Y G+ Sbjct: 591 TFSIMENNGQPCINDDEEMKEVDLPEIEAD-----SGCPQPVPPENGFIRNEKQLYLVGE 645 Query: 113 SVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGS 172 V +C T F G + C + W V EC + T Sbjct: 646 DVEISCLTGFETVGYQYFRCLPDGTWRQ----GDVECQRTECIKPVVQEVLTITPFQR-L 700 Query: 173 IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL 232 G S+ +C G+++ G C + W+ +L + G + Sbjct: 701 YRIGESIELTCPKGFVVAGPSRYTCQGN-SWTPPISNSLTCEKDTLTKL-KGHCQLGQKQ 758 Query: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCE 272 +E CV + P C+ Sbjct: 759 SGSECICMSPEEDCSHHSED--LCVFDTDSNDYFTSPACK 796 Score = 53.4 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 49/266 (18%), Positives = 77/266 (28%), Gaps = 31/266 (11%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 C P NG T S E + TY N + + + D + G W Sbjct: 500 CQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQ---------SPDYKSNAVDGQWGCW 550 Query: 587 SGPAPLCKLSLL---AVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR 643 S + C + +C++ G K E + TF G I Sbjct: 551 SSWS-TCDATYKRSRTRECNNPAPQRGGKRCEGEK--RQEEDCTFSIMEN---NGQPCIN 604 Query: 644 CKADNTWDPEIPVCEKETCQHVRQSLQELPAGSR-----VELVNTSCQDGYQLTGHAYQM 698 + + C + E V SC G++ G+ Y Sbjct: 605 DDEEMKEVDLPEIEADSGCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFR 664 Query: 699 CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK 758 C +G W + C+ C P V T + G + C +GF + G Sbjct: 665 C--LPDGTWRQGDVECQRTECIKPVVQEVLTITPFQR-LYRIGESIELTCPKGFVVAGPS 721 Query: 759 KLQCRSDSKGHGSWSGPSPQCLRSPP 784 + C+ + SW+ P L Sbjct: 722 RYTCQGN-----SWTPPISNSLTCEK 742 Score = 43.7 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 25/180 (13%), Positives = 47/180 (26%), Gaps = 13/180 (7%) Query: 836 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT 895 W T + C P G G + +S ++ C Sbjct: 553 WSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQ---EEDCTFS------IMENNGQPCI 603 Query: 896 HEGTWSQP--APHCK-EVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQ 952 ++ + P + + C P + E +++Y G V + C G+ G Sbjct: 604 NDDEEMKEVDLPEIEADSGCPQPVPPENGFIRNE-KQLYLVGEDVEISCLTGFETVGYQY 662 Query: 953 SQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQ 1012 +C D W C+ + + L I + S+ Sbjct: 663 FRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSR 722 >6H03-D nrPDB Length = 821 Score = 172 bits (434), Expect = 9e-43, Method: Composition-based stats. Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 25/214 (11%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP PP + +G FP G V YTCN G +SLIG RC E W Sbjct: 549 CPSPPALKDGFVQDEGTM-FPVGKNVVYTCNEG------YSLIGNPVARCG----EDLRW 597 Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646 C+ + C + +G + ++ Y + VT C G +L+G S C + Sbjct: 598 LVGEMHCQ----KIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGS 653 Query: 647 DNTWDPEIPVCEKETCQHVRQSL-QELPAGSRVELVNTS---CQDGYQLTGHAYQMCQDA 702 W PE+ + C L Q +P R E + S C+ Y+ G + +C Sbjct: 654 SLKWSPEM---KNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYEC-GPSLDVCAQD 709 Query: 703 ENGIWFKKIPLCK--VIHCHPPPVIVNGKHTGMM 734 E + +CK V+HC + G+ + + Sbjct: 710 ERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTL 743 Score = 155 bits (392), Expect = 7e-38, Method: Composition-based stats. Identities = 44/262 (16%), Positives = 77/262 (29%), Gaps = 39/262 (14%) Query: 258 IAGQGVAWTKMPVCEEIF------CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEE 311 + G W+ C + C +PPP GR Sbjct: 477 VDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETT------------------ 518 Query: 312 GVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTY 371 + +C + + P CP P L+ V + + Sbjct: 519 ---------ESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPV 569 Query: 372 NDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDP 431 V++ C G++L G+ RC W C+K P +++G + + Sbjct: 570 GKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTV 629 Query: 432 GTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKP------QHQ 485 G + SC+ G L G + C S W+P + + E Q + K Q+ Sbjct: 630 GEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQKENPLTQAVPKCQRWEKLQNS 689 Query: 486 FVRPDVNSSCGEGYKLSGSVYQ 507 + CG + + Sbjct: 690 RCVCKMPYECGPSLDVCAQDER 711 Score = 124 bits (310), Expect = 2e-28, Method: Composition-based stats. Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 5/140 (3%) Query: 841 PTCIKKAFIG---CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 897 P C + + CP PP +G F G +++Y+C++GY L+G + C + Sbjct: 536 PHCFPLSLVPTEFCPSPPALKDG-FVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGED 594 Query: 898 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 957 W HC+++ C P MDGIQ + Y G VT+ C G LEG C S Sbjct: 595 LRWLVGEMHCQKIACVLPVLMDGIQSH-PQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGS 653 Query: 958 DHQWNPPLAVCRSRSLAPVL 977 +W+P + R L Sbjct: 654 SLKWSPEMKNARCVQKENPL 673 Score = 102 bits (253), Expect = 1e-21, Method: Composition-based stats. Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 10/133 (7%) Query: 147 VSVFPLE-CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 205 +S+ P E CP+ P + +G E G +V Y+C GY L+G + C +W Sbjct: 541 LSLVPTEFCPSPPALKDGFVQDEG-TMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLV 599 Query: 206 VPPTCEEARCKSLGRFPNGKVKEP--PILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGV 263 C++ C L +G P P VG C G L+GP + C G + Sbjct: 600 GEMHCQKIAC-VLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLC---GSSL 655 Query: 264 AWTKMPVCEEIFC 276 W+ P + C Sbjct: 656 KWS--PEMKNARC 666 Score = 84.2 bits (206), Expect = 3e-16, Method: Composition-based stats. Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 5/125 (4%) Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVA 469 C +PP + +G +D F G ++ Y+CN GY L+G +C + W C+ Sbjct: 549 CPSPPALKDGFVQD-EGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKI 607 Query: 470 ACEAT----GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525 AC G Q + V V SC G L G C ++ W E++ + + Sbjct: 608 ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCV 667 Query: 526 TCPPP 530 P Sbjct: 668 QKENP 672 Score = 68.4 bits (165), Expect = 2e-11, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 50/134 (37%), Gaps = 11/134 (8%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82 C SPP + +G + T VG + Y+C+ + LIG C + W C Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLR----WLVGEMHC 604 Query: 83 EYFNKYSSCPEPIVPGGYK-IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141 + +C P++ G + Y G+ VT +C S+ G + C ++ W P Sbjct: 605 QKI----ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPE 660 Query: 142 RLPTCVSVFPLECP 155 E P Sbjct: 661 --MKNARCVQKENP 672 Score = 57.2 bits (136), Expect = 4e-08, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 64/211 (30%), Gaps = 14/211 (6%) Query: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC--KLSLLAVQCSHVH 606 T + CN P G S +GE+T D+E P C + C Sbjct: 494 KKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPP 553 Query: 607 IANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ--- 663 + + + V + C G++L G+ RC D W C+K C Sbjct: 554 ALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPV 613 Query: 664 --HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721 QS + P + E V SC G L G + +C + W P K C Sbjct: 614 LMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSL--KWS---PEMKNARCVQ 668 Query: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGF 752 + L + C + Sbjct: 669 KENPLTQAVPKCQRWEKLQNSRC--VCKMPY 697 Score = 49.9 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 678 VELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737 + V +C +GY L G+ C E+ W C+ I C P V+++G + Sbjct: 570 GKNVVYTCNEGYSLIGNPVARC--GEDLRWLVGEMHCQKIACVLP-VLMDGIQSHPQKPF 626 Query: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRC 788 + G +V+ C G L G C S K WS P + R Sbjct: 627 YTVGEKVTVSCSGGMSLEGPSAFLCGSSLK----WS-PEMKNARCVQKENP 672 >3ERB-A nrPDB Length = 223 Score = 166 bits (420), Expect = 4e-41, Method: Composition-based stats. Identities = 48/193 (24%), Positives = 76/193 (39%), Gaps = 10/193 (5%) Query: 88 YSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMW---GPTRLP 144 SCP+ + G S + G +T++C + S C+++ W G TR Sbjct: 1 APSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPS-PASRLCKSSGQWQTPGATRSL 59 Query: 145 TCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWS 204 + P+ CPA NG +T +GS G +V++ CE G++L G + C +G W Sbjct: 60 SKAVCKPVRCPAPVSFENGIYTPR-LGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 118 Query: 205 AVPPTCEEAR--CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQG 262 C+ C + G G V+ G + C L G C G G Sbjct: 119 GETAVCDNGAGHCPNPG-ISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQ--GNG 175 Query: 263 VAWTKMPVCEEIF 275 V P+C + + Sbjct: 176 VWSGTEPICRQPY 188 Score = 164 bits (415), Expect = 2e-40, Method: Composition-based stats. Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 14/173 (8%) Query: 853 PPPKTPNGNHTGGNIAR---FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPH--- 906 P N N +GG ++PG + YSC QG L A LC G W P Sbjct: 1 APSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSL 59 Query: 907 ----CKEVNCSSPADMDGIQKGLEPR-KMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 961 CK V C +P + PR Y G V+ ECEDG++L GSP QC+ + W Sbjct: 60 SKAVCKPVRCPAPVSFENGI--YTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMW 117 Query: 962 NPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQKE 1014 + AVC + + GI+ G + F V + + T +S++E Sbjct: 118 DGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERE 170 Score = 147 bits (371), Expect = 2e-35, Method: Composition-based stats. Identities = 50/195 (25%), Positives = 72/195 (36%), Gaps = 16/195 (8%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP I G + + GS++TY+C G + + +G W Sbjct: 4 CPQNVNISGGTFTLSHG--WAPGSLLTYSC-----------PQGLYPSPASRLCKSSGQW 50 Query: 336 SGPAPRCELS---TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR 392 P LS V+CP P + + + Y V F C GF L+GS + Sbjct: 51 QTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQ 110 Query: 393 CNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ 452 C G W+ VC+ PN R RF G ++Y C+ VL G + Sbjct: 111 CRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERE 170 Query: 453 CTSEGVWTPPVPQCK 467 C GVW+ P C+ Sbjct: 171 CQGNGVWSGTEPICR 185 Score = 142 bits (357), Expect = 8e-34, Method: Composition-based stats. Identities = 47/198 (23%), Positives = 77/198 (38%), Gaps = 23/198 (11%) Query: 491 VNSSCGEGYKLSGSVYQECQGTIPW-------FMEIRLCKEITCPPPPVIYNGAHTGSSL 543 + SC +G S + C+ + W + +CK + CP P NG +T L Sbjct: 27 LTYSCPQGLYPS-PASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYT-PRL 84 Query: 544 EDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS 603 +P G V++ C G F L G +C N G W G +C A C Sbjct: 85 GSYPVGGNVSFECEDG------FILRGSPVRQCRPN----GMWDGETAVCDNG--AGHCP 132 Query: 604 HVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ 663 + I+ G +G + + D V ++C S L GSS+ C+ + W P+C + Sbjct: 133 NPGISLGAVRTGFR--FGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSY 190 Query: 664 HVRQSLQELPAGSRVELV 681 + + S ++ Sbjct: 191 DFPEDVAPALGTSFSHML 208 Score = 127 bits (318), Expect = 3e-29, Method: Composition-based stats. Identities = 47/189 (24%), Positives = 69/189 (36%), Gaps = 15/189 (7%) Query: 678 VELVNTSCQDGYQLTGHAYQMCQ-----DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTG 732 L+ SC G A ++C+ +CK + C P NG +T Sbjct: 24 GSLLTYSCPQGLYP-SPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 82 Query: 733 MMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 792 + ++ G VS+EC+ GF L G QCR + G W G + C CPNP Sbjct: 83 RLG-SYPVGGNVSFECEDGFILRGSPVRQCRPN----GMWDGETAVCDNG--AGHCPNPG 135 Query: 793 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 852 + G +T + H D V C+ ++ GS C + W P C + P Sbjct: 136 ISLGAV--RTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFP 193 Query: 853 PPPKTPNGN 861 G Sbjct: 194 EDVAPALGT 202 Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 63/170 (37%), Gaps = 8/170 (4%) Query: 8 GVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCIT 67 G +L + C +P NG + VG + + C F L G C Sbjct: 54 GATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQC-- 111 Query: 68 KDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGN 127 + +G WD C+ N CP P + G +R + HGD V + C +N + G+ Sbjct: 112 --RPNGMWDGETAVCD--NGAGHCPNPGISLG-AVRTGFRFGHGDKVRYRCSSNLVLTGS 166 Query: 128 KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGL 177 CQ N +W T P C + + P G S +G+ P Sbjct: 167 SERECQGNGVWSGTE-PICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQ 215 Score = 104 bits (259), Expect = 2e-22, Method: Composition-based stats. Identities = 52/193 (26%), Positives = 69/193 (35%), Gaps = 14/193 (7%) Query: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778 C I G T ++ + G+ ++Y C QG Y C+S G W P Sbjct: 4 CPQNVNISGG--TFTLSHGWAPGSLLTYSCPQGLYPSPAS-RLCKSS----GQWQTPGAT 56 Query: 779 CLRSPPV---TRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT 835 S V RCP P +Y V +C GFI+ GS V +C + Sbjct: 57 RSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGM 116 Query: 836 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT 895 W C A CP P + TG RF G + Y C +L G + C Sbjct: 117 WDGETAVCDNGAGH-CPNPGISLGAVRTG---FRFGHGDKVRYRCSSNLVLTGSSERECQ 172 Query: 896 HEGTWSQPAPHCK 908 G WS P C+ Sbjct: 173 GNGVWSGTEPICR 185 Score = 100 bits (249), Expect = 3e-21, Method: Composition-based stats. Identities = 56/199 (28%), Positives = 71/199 (35%), Gaps = 24/199 (12%) Query: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAV------ 206 CP I G T + APG +TYSC G C SSG+W Sbjct: 3 SCPQNVNISGGTFTLSH--GWAPGSLLTYSCPQGLYPSPA-SRLCKSSGQWQTPGATRSL 59 Query: 207 -PPTCEEARCKSLGRFPNGKV-KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVA 264 C+ RC + F NG VG +F C++G+ L+G P +C G Sbjct: 60 SKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDG 119 Query: 265 WTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLR 324 T + CP+P L G +G V Y C N +L G S Sbjct: 120 ETAVCDNGAGHCPNPGISLGAVRTGFR---FGHGDKVRYRCSS------NLVLTGSSERE 170 Query: 325 CTVDSQKTGTWSGPAPRCE 343 C Q G WSG P C Sbjct: 171 C----QGNGVWSGTEPICR 185 Score = 97.3 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 17/190 (8%) Query: 348 AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR-CNAQGTWEP----- 401 A CP + G + + ++C G L S R C + G W+ Sbjct: 1 APSCPQNVNISGGTFTLSHGWAP-GSLLTYSCPQG--LYPSPASRLCKSSGQWQTPGATR 57 Query: 402 --SAPVCEKE-CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458 S VC+ C AP + NG + + G ++ + C G++L G QC G+ Sbjct: 58 SLSKAVCKPVRCPAPVSFENGI-YTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGM 116 Query: 459 WTPPVPQCKVAA--CEATGRQL-LTKPQHQFVRPD-VNSSCGEGYKLSGSVYQECQGTIP 514 W C A C G L + +F D V C L+GS +ECQG Sbjct: 117 WDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGV 176 Query: 515 WFMEIRLCKE 524 W +C++ Sbjct: 177 WSGTEPICRQ 186 Score = 81.9 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 68/192 (35%), Gaps = 20/192 (10%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG-------V 840 CP G +H ++ ++ C G + C + W Sbjct: 4 CPQNVNISGGTFTLSHG-WAPGSLLTYSCPQGLYPS-PASRLCKSSGQWQTPGATRSLSK 61 Query: 841 PTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTW 900 C + CP P NG +T + + G ++ + C+ G++L G + C G W Sbjct: 62 AVCKP---VRCPAPVSFENGIYT-PRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMW 117 Query: 901 SQPAPHCKEV--NCSSPADMDGIQKGLEPRKM-YQYGAVVTLECEDGYMLEGSPQSQCQS 957 C +C +P GI G + +G V C +L GS + +CQ Sbjct: 118 DGETAVCDNGAGHCPNP----GISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQG 173 Query: 958 DHQWNPPLAVCR 969 + W+ +CR Sbjct: 174 NGVWSGTEPICR 185 >1ZJK-A nrPDB Length = 403 Score = 141 bits (356), Expect = 1e-33, Method: Composition-based stats. Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 11/143 (7%) Query: 849 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQ 902 CP P PNG H A++ S C+ GY L+ L L C +G+W + Sbjct: 15 HACPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDR 73 Query: 903 PAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDH 959 P P C V+C P D G + + + Y AV+ CE+ + M + C++D Sbjct: 74 PMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 133 Query: 960 QWNPPLAVCRSRSLAPVLCGIAA 982 W +S + +CG++A Sbjct: 134 FWTSSKGE-KSLPVCEPVCGLSA 155 Score = 81.9 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 55/155 (35%), Gaps = 10/155 (6%) Query: 345 STSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGT 398 +++A CP+P VS + +Y D+ C G+ L S C G+ Sbjct: 11 TSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGS 70 Query: 399 WEPSAPVCE-KECQAPPNILNGQKEDRHMVRF-DPGTSIKYSCNPGYVLV--GEESIQCT 454 W+ P C +C P ++ +G+ E I+YSC + + + C Sbjct: 71 WDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCE 130 Query: 455 SEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRP 489 ++G WT + + CE Q Sbjct: 131 ADGFWTSSKGEKSLPVCEPVCGLSARTTGGQIYGG 165 Score = 73.0 bits (177), Expect = 6e-13, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 50/154 (32%), Gaps = 16/154 (10%) Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY------LLVGEKIINCLSSGKWSAVP 207 CP NGH + S + CE+GY L + C G W Sbjct: 17 CPYPMAPPNGHVSPVQ-AKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 75 Query: 208 PTCEEARCKSLGRFPNGKVKE---PPILRVGVTANFFCDEG-YRLQGPPSSR-CVIAGQG 262 P C C P+G+V+ P + + C+E Y ++ C G Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 135 Query: 263 VAW---TKMPVCEEIFCPSPPPILNGRHIGNSLA 293 + +PVCE + C G+ G A Sbjct: 136 TSSKGEKSLPVCEPV-CGLSARTTGGQIYGGQKA 168 Score = 63.0 bits (151), Expect = 7e-10, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 51/173 (29%), Gaps = 18/173 (10%) Query: 264 AWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTL 323 W CP P NG H+ A + C+ E + + T Sbjct: 5 GWKIHYTSTAHACPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTA 63 Query: 324 RCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVS--GQKDRYTYNDTVIFACMF 381 C QK G+W P P C + V C P L V TY + ++C Sbjct: 64 VC----QKDGSWDRPMPACSI----VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEE 115 Query: 382 GFTLK--GSKQIRCNAQGTWEPSA-----PVCEKECQAPPNILNGQKEDRHMV 427 F + C A G W S PVCE C GQ Sbjct: 116 TFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGQIYGGQKA 168 Score = 60.7 bits (145), Expect = 4e-09, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 52/151 (34%), Gaps = 18/151 (11%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGF------IMNGSRVIRCHTDNTWVPGVP 841 CP P ++ + Y D + C G+ + S C D +W +P Sbjct: 17 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 76 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNI-ARFSPGMSILYSCDQG-YLLVGEALL-LCTHEG 898 C + C PP P+G + I YSC++ Y + +C +G Sbjct: 77 ACSI---VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 133 Query: 899 TWS-----QPAPHCKEVNCSSPADMDGIQKG 924 W+ + P C+ V C A G Q Sbjct: 134 FWTSSKGEKSLPVCEPV-CGLSARTTGGQIY 163 Score = 59.9 bits (143), Expect = 6e-09, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 662 CQHVRQSLQELPAGSRVELVNTS--CQDGYQLT------GHAYQMCQDAENGIWFKKIPL 713 + + S C+ GY+L +CQ ++G W + +P Sbjct: 20 PMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQ--KDGSWDRPMPA 77 Query: 714 CKVIHCHPPPVIVNGKHTGMMAENF-LYGNEVSYECDQGFYLLGEK--KLQCRSD---SK 767 C ++ C PP + +G+ + Y + Y C++ FY + K C +D + Sbjct: 78 CSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTS 137 Query: 768 GHGSWSGPS--PQCLRSPPVT 786 G S P P C S T Sbjct: 138 SKGEKSLPVCEPVCGLSARTT 158 Score = 54.1 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 52/160 (32%), Gaps = 18/160 (11%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP P NG H + + + C G E + T C Q+ G+W Sbjct: 17 CPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVC----QKDGSW 71 Query: 587 SGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAP-YFYNDTVTFKCYSGFTLKGSSQIR- 643 P P C + V C + +G Y + + C F + + Sbjct: 72 DRPMPACSI----VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKY 127 Query: 644 -CKADNTWDP-----EIPVCEKETCQHVRQSLQELPAGSR 677 C+AD W +PVCE R + ++ G + Sbjct: 128 VCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGQIYGGQK 167 Score = 52.2 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 47/140 (33%), Gaps = 13/140 (9%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE--KSLLCITKDKVDGTWDKPAP 80 C P NG +S + C + L+ + DG+WD+P P Sbjct: 17 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 76 Query: 81 KCEYFNKYSSCPEPIVPGG----YKIRGSTPYRHGDSVTFACKTNFS--MNGNKSVWCQA 134 C + P +P G G T Y+ + ++C+ F + C+A Sbjct: 77 ACSIVD---CGPPDDLPSGRVEYITGPGVTTYK--AVIQYSCEETFYTMKVNDGKYVCEA 131 Query: 135 NNMWGPTRLPTCVSVFPLEC 154 + W ++ + V C Sbjct: 132 DGFWTSSKGEKSLPVCEPVC 151 Score = 50.7 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 50/153 (32%), Gaps = 19/153 (12%) Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEI 654 C + +S +A Y D+ + C +G+ L S C+ D +WD + Sbjct: 16 ACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 75 Query: 655 PVCEKETCQHVR-------QSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIW 707 P C C + + + ++ SC++ + +G W Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 135 Query: 708 F-----KKIPLCKVIHCHPPPVIVNGKHTGMMA 735 K +P+C+ + C G+ G Sbjct: 136 TSSKGEKSLPVCEPV-CGLSARTTGGQIYGGQK 167 Score = 45.7 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 11/100 (11%) Query: 470 ACE----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEI 519 AC + ++ + C GY+L S CQ W + Sbjct: 16 ACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 75 Query: 520 RLCKEITCPPPPVIYNGAHTG-SSLEDFPYGTTVTYTCNP 558 C + C PP + +G + Y + Y+C Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEE 115 Score = 38.7 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 14/104 (13%) Query: 16 PGVLGISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73 P + CG P + +GR+ Y + P VI+YSC TF + K + DG Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTM--KVNDGKYVCEADG 133 Query: 74 TW-----DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGD 112 W +K P CE C G +I G + GD Sbjct: 134 FWTSSKGEKSLPVCEPV-----CGLSARTTGGQIYGGQKAKPGD 172 >4FXG-G nrPDB Length = 154 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 11/143 (7%) Query: 849 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL------CTHEGTWSQ 902 CP P PNG H A++ S C+ GY L+ L L C +G+W + Sbjct: 8 HACPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDR 66 Query: 903 PAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDH 959 P P C V+C P D G + + + Y AV+ CE+ + M + C++D Sbjct: 67 PMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 126 Query: 960 QWNPPLAVCRSRSLAPVLCGIAA 982 W +S + +CG++A Sbjct: 127 FWTSSKGE-KSLPVCEPVCGLSA 148 Score = 71.9 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 54/141 (38%), Gaps = 10/141 (7%) Query: 345 STSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGT 398 +++A CP+P VS + +Y D+ C G+ L S C G+ Sbjct: 4 TSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGS 63 Query: 399 WEPSAPVCE-KECQAPPNILNGQKEDRHMVRF-DPGTSIKYSCNPGYVLV--GEESIQCT 454 W+ P C +C P ++ +G+ E I+YSC + + + C Sbjct: 64 WDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCE 123 Query: 455 SEGVWTPPVPQCKVAACEATG 475 ++G WT + + CE Sbjct: 124 ADGFWTSSKGEKSLPVCEPVC 144 Score = 63.0 bits (151), Expect = 6e-10, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 48/147 (32%), Gaps = 16/147 (10%) Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY------LLVGEKIINCLSSGKWSAVP 207 CP NGH + S + CE+GY L + C G W Sbjct: 10 CPYPMAPPNGHVSPVQ-AKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 68 Query: 208 PTCEEARCKSLGRFPNGKVKE---PPILRVGVTANFFCDEG-YRLQGPPSSR-CVIAGQG 262 P C C P+G+V+ P + + C+E Y ++ C G Sbjct: 69 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 128 Query: 263 VAW---TKMPVCEEIFCPSPPPILNGR 286 + +PVCE + C GR Sbjct: 129 TSSKGEKSLPVCEPV-CGLSARTTGGR 154 Score = 54.1 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 18/146 (12%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P NG H+ A + C+ E + + T C QK G+W Sbjct: 10 CPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVC----QKDGSW 64 Query: 336 SGPAPRCELSTSAVQCPHPQILRGRMVS--GQKDRYTYNDTVIFACMFGFTLK--GSKQI 391 P P C + V C P L V TY + ++C F + Sbjct: 65 DRPMPACSI----VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKY 120 Query: 392 RCNAQGTWEPSA-----PVCEKECQA 412 C A G W S PVCE C Sbjct: 121 VCEADGFWTSSKGEKSLPVCEPVCGL 146 Score = 52.6 bits (124), Expect = 9e-07, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 10/107 (9%) Query: 688 GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENF-LYGNEVSY 746 G+ +CQ ++G W + +P C ++ C PP + +G+ + Y + Y Sbjct: 47 GHLPLKSFTAVCQ--KDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQY 104 Query: 747 ECDQGFYLLGEK--KLQCRSD-----SKGHGSWSGPSPQCLRSPPVT 786 C++ FY + K C +D SKG S P C S T Sbjct: 105 SCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTT 151 Score = 51.1 bits (120), Expect = 3e-06, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 53/148 (35%), Gaps = 18/148 (12%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGF------IMNGSRVIRCHTDNTWVPGVP 841 CP P ++ + Y D + C G+ + S C D +W +P Sbjct: 10 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 69 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNI-ARFSPGMSILYSCDQGYLL--VGEALLLCTHEG 898 C + + C PP P+G + I YSC++ + V + +C +G Sbjct: 70 AC---SIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 126 Query: 899 TWS-----QPAPHCKEVNCSSPADMDGI 921 W+ + P C+ V C A G Sbjct: 127 FWTSSKGEKSLPVCEPV-CGLSARTTGG 153 Score = 46.1 bits (107), Expect = 9e-05, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 46/142 (32%), Gaps = 18/142 (12%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP P NG H + + + C G E + T C Q+ G+W Sbjct: 10 CPYPMAPPNG-HVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVC----QKDGSW 64 Query: 587 SGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAP-YFYNDTVTFKCYSGFTLKGSSQIR- 643 P P C + V C + +G Y + + C F + + Sbjct: 65 DRPMPACSI----VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKY 120 Query: 644 -CKADNTWDP-----EIPVCEK 659 C+AD W +PVCE Sbjct: 121 VCEADGFWTSSKGEKSLPVCEP 142 Score = 45.7 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 46/138 (33%), Gaps = 9/138 (6%) Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE--KSLLCITKDKVDGTWDKPAP 80 C P NG +S + C + L+ + DG+WD+P P Sbjct: 10 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 69 Query: 81 KCEYFNKYSSCPEPIVPGGYK--IRGSTPYRHGDSVTFACKTNFS--MNGNKSVWCQANN 136 C + P +P G I G + + ++C+ F + C+A+ Sbjct: 70 ACSIVD---CGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 126 Query: 137 MWGPTRLPTCVSVFPLEC 154 W ++ + V C Sbjct: 127 FWTSSKGEKSLPVCEPVC 144 Score = 44.1 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 49/147 (33%), Gaps = 19/147 (12%) Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEI 654 C + +S +A Y D+ + C +G+ L S C+ D +WD + Sbjct: 9 ACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 68 Query: 655 PVCEKETCQHVR-------QSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIW 707 P C C + + + ++ SC++ + +G W Sbjct: 69 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 128 Query: 708 F-----KKIPLCKVIHCHPPPVIVNGK 729 K +P+C+ + C G+ Sbjct: 129 TSSKGEKSLPVCEPV-CGLSARTTGGR 154 Score = 40.7 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 23/71 (32%), Gaps = 1/71 (1%) Query: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG-SSLEDFP 547 + +G+ S CQ W + C + C PP + +G + Sbjct: 38 CETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTT 97 Query: 548 YGTTVTYTCNP 558 Y + Y+C Sbjct: 98 YKAVIQYSCEE 108 Score = 32.2 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 16 PGVLGISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73 P + CG P + +GR+ Y + P VI+YSC TF + K + DG Sbjct: 69 PACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTM--KVNDGKYVCEADG 126 Query: 74 TW-----DKPAPKCEYFNKYSS 90 W +K P CE S+ Sbjct: 127 FWTSSKGEKSLPVCEPVCGLSA 148 >4C16-A nrPDB Length = 280 Score = 122 bits (305), Expect = 8e-28, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 2/124 (1%) Query: 849 IGCPPPPKTPNGNH-TGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 907 + C +G+ + FS S SCD+GYL + C G WS P P C Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC 216 Query: 908 KEVNCSSPADM-DGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLA 966 V C + + +G + + + + T +CE+G+ L G+ QC S W+ Sbjct: 217 NVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKP 276 Query: 967 VCRS 970 C++ Sbjct: 277 TCKA 280 Score = 120 bits (300), Expect = 4e-27, Method: Composition-based stats. Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Query: 152 LECPALPMIHNGHHT-SENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210 + C AL +G S +G+ + S + SC+ GYL + + C+SSG+WSA P C Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC 216 Query: 211 EEARCKSLGRFPNGKV---KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK 267 C ++ NG V + P T F C+EG+ L G S +C +G + Sbjct: 217 NVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD--NE 274 Query: 268 MPVCEE 273 P C+ Sbjct: 275 KPTCKA 280 Score = 102 bits (253), Expect = 9e-22, Method: Composition-based stats. Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 17/137 (12%) Query: 525 ITCPPPPVIYNG-AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 583 + C +G L +F Y ++ + +C+ G + T++C S+ Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRG------YLPSSMETMQCMSS---- 206 Query: 584 GTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKGSSQ 641 G WS P P C + V+C V + ANG+ + F +N T TF C GF L G+ Sbjct: 207 GEWSAPIPACNV----VECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQS 262 Query: 642 IRCKADNTWDPEIPVCE 658 ++C + WD E P C+ Sbjct: 263 LQCTSSGNWDNEKPTCK 279 Score = 101 bits (252), Expect = 1e-21, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 61/162 (37%), Gaps = 18/162 (11%) Query: 247 RLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCD 306 + +C G+ ++ C + P + L N SY S + +CD Sbjct: 135 ETINNYTCKCDPGFSGLKCEQIVNCTALE----SPEHGSLVCSHPLGNFSYNSSCSISCD 190 Query: 307 PDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL-STSAVQCPHPQILRGRMVSGQ 365 ++ T++C +G WS P P C + AV P + G Sbjct: 191 R------GYLPSSMETMQC----MSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGS 240 Query: 366 KDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE 407 + +N T F C GF L G++ ++C + G W+ P C+ Sbjct: 241 ---FPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 101 bits (251), Expect = 2e-21, Method: Composition-based stats. Identities = 38/147 (25%), Positives = 57/147 (38%), Gaps = 17/147 (11%) Query: 390 QIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRH-MVRFDPGTSIKYSCNPGYVLVGE 448 C + C A + +G H + F +S SC+ GY+ Sbjct: 139 NYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSM 198 Query: 449 ESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVN-----------SSCGE 497 E++QC S G W+ P+P C V C+A +T P + FV N C E Sbjct: 199 ETMQCMSSGEWSAPIPACNVVECDA-----VTNPANGFVECFQNPGSFPWNTTCTFDCEE 253 Query: 498 GYKLSGSVYQECQGTIPWFMEIRLCKE 524 G++L G+ +C + W E CK Sbjct: 254 GFELMGAQSLQCTSSGNWDNEKPTCKA 280 Score = 97.7 bits (241), Expect = 3e-20, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 6/132 (4%) Query: 780 LRSPPVTRCPNPEVKHGY--KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 837 L+ + C E + +S+N + C+ G++ + ++C + W Sbjct: 151 LKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWS 210 Query: 838 PGVPTCIKKAFIGCPPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH 896 +P C + C NG N F + + C++G+ L+G L CT Sbjct: 211 APIPAC---NVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTS 267 Query: 897 EGTWSQPAPHCK 908 G W P CK Sbjct: 268 SGNWDNEKPTCK 279 Score = 87.7 bits (215), Expect = 2e-17, Method: Composition-based stats. Identities = 43/158 (27%), Positives = 60/158 (37%), Gaps = 19/158 (12%) Query: 624 DTVTFKCYSGFT-LKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVN 682 + T KC GF+ LK + C A E P C H L S + Sbjct: 138 NNYTCKCDPGFSGLKCEQIVNCTAL-----ESPEHGSLVCSHP------LGNFSYNSSCS 186 Query: 683 TSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE-NFLYG 741 SC GY + C + G W IP C V+ C NG +F + Sbjct: 187 ISCDRGYLPSSMETMQCMSS--GEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWN 244 Query: 742 NEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779 +++C++GF L+G + LQC S G+W P C Sbjct: 245 TTCTFDCEEGFELMGAQSLQCTSS----GNWDNEKPTC 278 Score = 70.7 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 4/123 (3%) Query: 349 VQCPHPQILRGRMVSGQKDR--YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406 V C + + ++YN + +C G+ + ++C + G W P C Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC 216 Query: 407 E-KECQAPPNILNGQKEDRHMV-RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVP 464 EC A N NG E F T+ + C G+ L+G +S+QCTS G W P Sbjct: 217 NVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKP 276 Query: 465 QCK 467 CK Sbjct: 277 TCK 279 Score = 65.7 bits (158), Expect = 1e-10, Method: Composition-based stats. Identities = 38/165 (23%), Positives = 59/165 (35%), Gaps = 17/165 (10%) Query: 438 SCNP-GYVLVGEESIQCTSEGVWTP----PVPQCKVAACEATGRQLLTKPQHQF-VRPDV 491 SC+ G + + C + ++ + C G + + P F Sbjct: 126 SCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSC 185 Query: 492 NSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHT-GSSLEDFPYGT 550 + SC GY S +C + W I C + C NG + FP+ T Sbjct: 186 SISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNT 245 Query: 551 TVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595 T T+ C G F L+G +++CTS+ G W P CK Sbjct: 246 TCTFDCEEG------FELMGAQSLQCTSS----GNWDNEKPTCKA 280 Score = 60.3 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 59/154 (38%), Gaps = 19/154 (12%) Query: 196 NCLSSGKWSAVPPTCEEAR-CKSLGRFPNGKV--KEP-PILRVGVTANFFCDEGYRLQGP 251 C +S + CE+ C +L +G + P + + CD GY Sbjct: 141 TCKCDPGFSGLK--CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSM 198 Query: 252 PSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH-IGNSLANVSYGSIVTYTCDPDPE 310 + +C+ +G+ A +P C + C + NG + + + + T+ C+ Sbjct: 199 ETMQCMSSGEWSA--PIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEE--- 253 Query: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344 F L+G +L+CT +G W P C+ Sbjct: 254 ---GFELMGAQSLQCT----SSGNWDNEKPTCKA 280 Score = 56.5 bits (134), Expect = 6e-08, Method: Composition-based stats. Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 11/114 (9%) Query: 109 RHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVS----------VFPLECPALP 158 HG V NFS N + S+ C + C+S +EC A+ Sbjct: 166 EHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVT 225 Query: 159 MIHNGHHTS-ENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCE 211 NG +N GS + T+ CE G+ L+G + + C SSG W PTC+ Sbjct: 226 NPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 53.4 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 50/158 (31%), Gaps = 17/158 (10%) Query: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVH-------IANGYKISGKEAP-YFYND 624 C+ + + T + C ++C + +G + + YN Sbjct: 124 NTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNS 183 Query: 625 TVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQS-------LQELPAGSR 677 + + C G+ ++C + W IP C C V Q + Sbjct: 184 SCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPW 243 Query: 678 VELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 715 C++G++L G C +G W + P CK Sbjct: 244 NTTCTFDCEEGFELMGAQSLQC--TSSGNWDNEKPTCK 279 Score = 43.7 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 47/134 (35%), Gaps = 17/134 (12%) Query: 21 ISCGSPPPILNGRI--SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKP 78 ++C + +G + S+ + + SC + +++ C+ G W P Sbjct: 157 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCM----SSGEWSAP 212 Query: 79 APKCEYFNKYSSCPEPIVPGGYKI-----RGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133 P C C P + GS P+ + TF C+ F + G +S+ C Sbjct: 213 IPACNVVE----CDAVTNPANGFVECFQNPGSFPWN--TTCTFDCEEGFELMGAQSLQCT 266 Query: 134 ANNMWGPTRLPTCV 147 ++ W + Sbjct: 267 SSGNWDNEKPTCKA 280 Score = 42.2 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 16 PGVLGISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73 P + C + NG + + P T + C F L+G +SL C G Sbjct: 214 PACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCT----SSG 269 Query: 74 TWDKPAPKCE 83 WD P C+ Sbjct: 270 NWDNEKPTCK 279 >4KKD-A nrPDB Length = 433 Score = 115 bits (287), Expect = 1e-25, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 59/159 (37%), Gaps = 17/159 (10%) Query: 346 TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTW 399 + +CP Q + + +Y + D V+ +C G+ + + QI C GTW Sbjct: 1 MAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTW 60 Query: 400 EPSAPVCE-KECQAPPNILNG-QKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCT 454 P C+ +C+AP + +G + IKYSC Y + C+ Sbjct: 61 SNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCS 120 Query: 455 SEGVWTPPV-----PQCKVAACEATGRQLLTKPQHQFVR 488 ++GVW V P C C R L + Q Sbjct: 121 AQGVWMNKVLGRSLPTCLP-ECGQPSRSLPSLVQRIIGG 158 Score = 87.7 bits (215), Expect = 3e-17, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 676 SRVELVNTSCQDGYQLTGHAYQM----CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHT 731 + V SC GY++ +M + ++G W KIP CK++ C P + +G T Sbjct: 25 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLIT 84 Query: 732 GMMAENF-LYGNEVSYECDQGFYLL 755 N Y +E+ Y C + +Y + Sbjct: 85 FSTRNNLTTYKSEIKYSCQEPYYKM 109 Score = 81.5 bits (199), Expect = 2e-15, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 56/143 (39%), Gaps = 12/143 (8%) Query: 847 AFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL------LLCTHEGTW 900 A CP +G + A++ +L SCD GY ++ + + + C +GTW Sbjct: 2 AGNECPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTW 60 Query: 901 SQPAPHCKEVNCSSPADMDGIQKGLEPR-KMYQYGAVVTLECEDGYMLE---GSPQSQCQ 956 S P CK V+C +P +++ R + Y + + C++ Y + C Sbjct: 61 SNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCS 120 Query: 957 SDHQWNPPLAVCRSRSLAPVLCG 979 + W + RS CG Sbjct: 121 AQGVWMN-KVLGRSLPTCLPECG 142 Score = 64.2 bits (154), Expect = 3e-10, Method: Composition-based stats. Identities = 35/163 (21%), Positives = 55/163 (33%), Gaps = 23/163 (14%) Query: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI------INCLSSGKWSAV 206 ECP L +G V SC++GY ++ + + I CL G WS Sbjct: 5 ECPELQPPVHGKIEPSQ-AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 63 Query: 207 PPTCEEARCKSLGRFPNGKVKEPPILR---VGVTANFFCDEGYRLQGPPSS---RCVIAG 260 PTC+ C++ G +G + + C E Y ++ C G Sbjct: 64 IPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQG 123 Query: 261 QGVAW-------TKMPVCEEIFCPSPP---PILNGRHIGNSLA 293 + T +P C + P I+ GR+ L Sbjct: 124 VWMNKVLGRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLF 166 Score = 63.8 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 19/148 (12%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P ++G+ I S A + V +CD + + + + + C D GTW Sbjct: 6 CPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKD----GTW 60 Query: 336 SGPAPRCELSTSAVQCPHPQILRGRMV--SGQKDRYTYNDTVIFACMFGFTLKGSKQ--- 390 S P C++ V C P L ++ S + + TY + ++C + + Sbjct: 61 SNKIPTCKI----VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGI 116 Query: 391 IRCNAQGTWEP-----SAPVCEKECQAP 413 C+AQG W S P C EC P Sbjct: 117 YTCSAQGVWMNKVLGRSLPTCLPECGQP 144 Score = 61.1 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 54/143 (37%), Gaps = 20/143 (13%) Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEI 654 +C + KI +A YF+ D V C +G+ + + QI C D TW +I Sbjct: 5 ECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKI 64 Query: 655 PVCEKETCQHV-RQSLQELPAGSRVEL------VNTSCQDGYQ-LTGHAYQMCQDAENGI 706 P C+ C+ + +R L + SCQ+ Y + + + + G+ Sbjct: 65 PTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGV 124 Query: 707 WFKK-----IPLCKVIHCHPPPV 724 W K +P C C P Sbjct: 125 WMNKVLGRSLPTCLP-ECGQPSR 146 Score = 59.5 bits (142), Expect = 7e-09, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 53/145 (36%), Gaps = 19/145 (13%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP + K+ + + Y D V V C+ G+ + V I C D TW +P Sbjct: 6 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP 65 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNIARF-SPGMSILYSC-DQGYLLVGEAL--LLCTHE 897 TC + C P + +G T + I YSC + Y ++ C+ + Sbjct: 66 TCKI---VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQ 122 Query: 898 GTWS-----QPAPHCKEVNCSSPAD 917 G W + P C C P+ Sbjct: 123 GVWMNKVLGRSLPTCLP-ECGQPSR 146 Score = 52.6 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 35/94 (37%), Gaps = 7/94 (7%) Query: 472 EATGRQLLTKPQHQFVRPDVNSSCGEGYKL------SGSVYQECQGTIPWFMEIRLCKEI 525 ++ F + V SC GYK+ + EC W +I CK + Sbjct: 11 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIV 70 Query: 526 TCPPPPVIYNGAHTGSSLEDF-PYGTTVTYTCNP 558 C P + +G T S+ + Y + + Y+C Sbjct: 71 DCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQE 104 Score = 49.1 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 51/153 (33%), Gaps = 20/153 (13%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP +G S + + V +C+ G + + + I C + GTW Sbjct: 6 CPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIEC----LKDGTW 60 Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGK--EAPYFYNDTVTFKCYSGFT--LKGSSQI 642 S P CK+ V C I+ Y + + C + L ++ I Sbjct: 61 SNKIPTCKI----VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGI 116 Query: 643 -RCKADNTWDPE-----IPVCEKETCQHVRQSL 669 C A W + +P C E C +SL Sbjct: 117 YTCSAQGVWMNKVLGRSLPTCLPE-CGQPSRSL 148 Score = 47.6 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 30/162 (18%), Positives = 53/162 (32%), Gaps = 16/162 (9%) Query: 20 GISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDK--VDGTWDK 77 G C P ++G+I + SC ++++ + + + + DGTW Sbjct: 3 GNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSN 62 Query: 78 PAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHG---DSVTFACKTNFSM---NGNKSVW 131 P C+ + C P I ST + ++C+ + N Sbjct: 63 KIPTCKIVD----CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 118 Query: 132 CQANNMWG----PTRLPTCVSVFPLECPALPMIHNGHHTSEN 169 C A +W LPTC+ +LP + N Sbjct: 119 CSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVQRIIGGRN 160 >4IGD-A nrPDB Length = 406 Score = 115 bits (287), Expect = 1e-25, Method: Composition-based stats. Identities = 34/142 (23%), Positives = 55/142 (38%), Gaps = 16/142 (11%) Query: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQG 397 S + +CP Q + + +Y + D V+ +C G+ + + QI C G Sbjct: 1 ASMTGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG 60 Query: 398 TWEPSAPVCE-KECQAPPNILNG-QKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQ 452 TW P C+ +C+AP + +G + IKYSC Y + Sbjct: 61 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 120 Query: 453 CTSEGVWTPPV-----PQCKVA 469 C+++GVW V P C Sbjct: 121 CSAQGVWMNKVLGRSLPTCLPV 142 Score = 87.7 bits (215), Expect = 2e-17, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 676 SRVELVNTSCQDGYQLTGHAYQM----CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHT 731 + V SC GY++ +M + ++G W KIP CK++ C P + +G T Sbjct: 27 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLIT 86 Query: 732 GMMAENF-LYGNEVSYECDQGFYLL 755 N Y +E+ Y C + +Y + Sbjct: 87 FSTRNNLTTYKSEIKYSCQEPYYKM 111 Score = 83.0 bits (203), Expect = 6e-16, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 12/141 (8%) Query: 850 GCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL------LLCTHEGTWSQP 903 CP +G + A++ +L SCD GY ++ + + + C +GTWS Sbjct: 7 ECPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 65 Query: 904 APHCKEVNCSSPADMDGIQKGLEPR-KMYQYGAVVTLECEDGYMLE---GSPQSQCQSDH 959 P CK V+C +P +++ R + Y + + C++ Y + C + Sbjct: 66 IPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQG 125 Query: 960 QWNPPLAVCRSRSLAPVLCGI 980 W + RS +CG+ Sbjct: 126 VWMN-KVLGRSLPTCLPVCGL 145 Score = 65.3 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 22/143 (15%) Query: 408 KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE------SIQCTSEGVWTP 461 EC ++G+ E ++ + SC+ GY ++ + I+C +G W+ Sbjct: 6 NECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSN 64 Query: 462 PVPQCKVAACEATG------RQLLTKPQHQFVRPDVNSSCGEGYKLSGSVY---QECQGT 512 +P CK+ C A G T+ + ++ SC E Y + C Sbjct: 65 KIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQ 124 Query: 513 IPWFME-----IRLCKEITCPPP 530 W + + C + C P Sbjct: 125 GVWMNKVLGRSLPTCLPV-CGLP 146 Score = 63.4 bits (152), Expect = 5e-10, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 49/142 (34%), Gaps = 17/142 (11%) Query: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI------INCLSSGKWSAV 206 ECP L +G V SC++GY ++ + + I CL G WS Sbjct: 7 ECPELQPPVHGKIEPSQ-AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 65 Query: 207 PPTCEEARCKSLGRFPNGKVKEPPILR---VGVTANFFCDEGYRLQGPPSS---RCVIAG 260 PTC+ C++ G +G + + C E Y ++ C G Sbjct: 66 IPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQG 125 Query: 261 QGVAW---TKMPVCEEIFCPSP 279 + +P C + C P Sbjct: 126 VWMNKVLGRSLPTCLPV-CGLP 146 Score = 62.2 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 57/147 (38%), Gaps = 20/147 (13%) Query: 595 LSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADN 648 S+ +C + KI +A YF+ D V C +G+ + + QI C D Sbjct: 1 ASMTGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG 60 Query: 649 TWDPEIPVCEKETCQHV-RQSLQELPAGSRVEL------VNTSCQDGYQ-LTGHAYQMCQ 700 TW +IP C+ C+ + +R L + SCQ+ Y + + + Sbjct: 61 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 120 Query: 701 DAENGIWFKK-----IPLCKVIHCHPP 722 + G+W K +P C + C P Sbjct: 121 CSAQGVWMNKVLGRSLPTCLPV-CGLP 146 Score = 59.9 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 53/143 (37%), Gaps = 19/143 (13%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP + K+ + + Y D V V C+ G+ + V I C D TW +P Sbjct: 8 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP 67 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNIARF-SPGMSILYSC-DQGYLLVGEAL--LLCTHE 897 TC + C P + +G T + I YSC + Y ++ C+ + Sbjct: 68 TCKI---VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQ 124 Query: 898 GTWS-----QPAPHCKEVNCSSP 915 G W + P C V C P Sbjct: 125 GVWMNKVLGRSLPTCLPV-CGLP 146 Score = 53.0 bits (125), Expect = 7e-07, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 35/94 (37%), Gaps = 7/94 (7%) Query: 472 EATGRQLLTKPQHQFVRPDVNSSCGEGYKL------SGSVYQECQGTIPWFMEIRLCKEI 525 ++ F + V SC GYK+ + EC W +I CK + Sbjct: 13 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIV 72 Query: 526 TCPPPPVIYNGAHTGSSLEDF-PYGTTVTYTCNP 558 C P + +G T S+ + Y + + Y+C Sbjct: 73 DCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQE 106 Score = 47.6 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 53/161 (32%), Gaps = 21/161 (13%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP +G S + + V +C+ G + + + I C + GTW Sbjct: 8 CPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIEC----LKDGTW 62 Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGK--EAPYFYNDTVTFKCYSGFT--LKGSSQI 642 S P CK+ V C I+ Y + + C + L ++ I Sbjct: 63 SNKIPTCKI----VDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGI 118 Query: 643 -RCKADNTWDPE-----IPVCEK--ETCQHVRQSLQELPAG 675 C A W + +P C + R+ + ++ G Sbjct: 119 YTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSRKLMAQIFNG 159 Score = 47.2 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 43/127 (33%), Gaps = 12/127 (9%) Query: 20 GISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDK--VDGTWDK 77 G C P ++G+I + SC ++++ + + + + DGTW Sbjct: 5 GNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSN 64 Query: 78 PAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHG---DSVTFACKTNFSM---NGNKSVW 131 P C+ + C P I ST + ++C+ + N Sbjct: 65 KIPTCKIVD----CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 120 Query: 132 CQANNMW 138 C A +W Sbjct: 121 CSAQGVW 127 Score = 46.4 bits (108), Expect = 7e-05, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 56/163 (34%), Gaps = 17/163 (10%) Query: 214 RCKSLGRFPNGKV-KEPPILRVGVTANFFCDEGYRL------QGPPSSRCVIAGQGVAWT 266 C L +GK+ CD GY++ C+ G Sbjct: 7 ECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWS--N 64 Query: 267 KMPVCEEIFCPSPPPILNGRHIGNSLANV-SYGSIVTYTCDPDPEEGVNFILIGESTLRC 325 K+P C+ + C +P + +G ++ N+ +Y S + Y+C + ++ +T Sbjct: 65 KIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPY-----YKMLNNNTGIY 119 Query: 326 TVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368 T +Q G W L T C P+ R M R Sbjct: 120 TCSAQ--GVWMNKVLGRSLPTCLPVCGLPKFSRKLMAQIFNGR 160 >4J1Y-A nrPDB Length = 397 Score = 108 bits (270), Expect = 1e-23, Method: Composition-based stats. Identities = 38/156 (24%), Positives = 56/156 (35%), Gaps = 20/156 (12%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK------GSKQIRCNAQGTWEPSAP 404 CP + K +Y + D V C+ GF + S C + G W S Sbjct: 3 CPKEDTP-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 405 VCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT 460 C+ +C P +I NG+ ED F G+ I+Y+C Y + G C G W Sbjct: 62 KCQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWV 119 Query: 461 -----PPVPQCKVAACEATGRQLLTKPQHQFVRPDV 491 P +P+C C R+ + D Sbjct: 120 NEVLGPELPKCVPV-CGVP-REPFEEKARAIGGSDA 153 Score = 71.5 bits (173), Expect = 2e-12, Method: Composition-based stats. Identities = 24/138 (17%), Positives = 46/138 (33%), Gaps = 15/138 (10%) Query: 855 PKTPNGNHTG---GNIARFSPGMSILYSCDQGYLLVGEA------LLLCTHEGTWSQPAP 905 P A++ + +C G+ +V C G WS Sbjct: 2 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 906 HCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE---GSPQSQCQSDHQWN 962 C+ V+C P ++ + E + +G+V+ CE+ Y G + C + W Sbjct: 62 KCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWV 119 Query: 963 PPLAVCRSRSLAPVLCGI 980 + + +CG+ Sbjct: 120 NEV-LGPELPKCVPVCGV 136 Score = 61.5 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 21/145 (14%) Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFS----MNGNKSVW--CQANNMWGPTRLP 144 CP+ P Y D V C F G S + CQ+N W Sbjct: 3 CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS----N 58 Query: 145 TCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV---GEKIINCLSSG 201 + + P++C I NG E+ S G + Y+CE Y + G +C +G Sbjct: 59 SKLKCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNG 116 Query: 202 KW-----SAVPPTCEEARCKSLGRF 221 W P C C Sbjct: 117 SWVNEVLGPELPKCVPV-CGVPREP 140 Score = 60.7 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 17/138 (12%) Query: 664 HVRQSLQELPAGSRV--ELVNTSCQDGYQLT----GHAYQMCQDAENGIWFKKIPLCKVI 717 S+ E V ++V +C DG+++ G NG W C+ + Sbjct: 7 DTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPV 66 Query: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSWSG 774 C P I NGK E+ L+G+ + Y C++ +Y + G + C + GSW Sbjct: 67 DCGIPESIENGKVEDP--ESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGN----GSWVN 120 Query: 775 PS--PQCLRSPPVTRCPN 790 P+ + PV P Sbjct: 121 EVLGPELPKCVPVCGVPR 138 Score = 58.4 bits (139), Expect = 2e-08, Method: Composition-based stats. Identities = 35/135 (25%), Positives = 49/135 (36%), Gaps = 15/135 (11%) Query: 173 IAPGLSVTYSCESGYLLVGEKI------INCLSSGKWSAVPPTCEEARCKSLGRFPNGKV 226 V +C G+ +V ++ C S+GKWS C+ C NGKV Sbjct: 20 YVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKV 79 Query: 227 KEPPILRVGVTANFFCDEGYRLQ---GPPSSRCVIAGQGVAWT---KMPVCEEIFCPSP- 279 ++P G + C+E Y G C G V ++P C + C P Sbjct: 80 EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPV-CGVPR 138 Query: 280 -PPILNGRHIGNSLA 293 P R IG S A Sbjct: 139 EPFEEKARAIGGSDA 153 Score = 55.7 bits (132), Expect = 1e-07, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 21/145 (14%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP E + Y D+V + C GF + RV C ++ W Sbjct: 3 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV---GEALLLCTHEG 898 C + C P NG F G I Y+C++ Y + G C G Sbjct: 62 KCQP---VDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNG 116 Query: 899 TWSQ-----PAPHCKEVNCSSPADM 918 +W P C V C P + Sbjct: 117 SWVNEVLGPELPKCVPV-CGVPREP 140 Score = 54.9 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 36/113 (31%), Gaps = 12/113 (10%) Query: 488 RPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541 R V +C +G+++ S Y CQ W C+ + C P I NG Sbjct: 23 RDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDP 82 Query: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPA-PLC 593 F G+ + YTC G C N GP P C Sbjct: 83 ESTLF--GSVIRYTCEEPYYYMEN---GGGGEYHCAGNGSWVNEVLGPELPKC 130 Score = 50.3 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 46/153 (30%), Gaps = 20/153 (13%) Query: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587 P P + + + + V TC G E C SN G WS Sbjct: 2 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSN----GKWS 57 Query: 588 GPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLK---GSSQIR 643 C+ V C I NG + + + + C + G + Sbjct: 58 NSKLKCQ----PVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYH 111 Query: 644 CKADNTW-----DPEIPVCEKETCQHVRQSLQE 671 C + +W PE+P C C R+ +E Sbjct: 112 CAGNGSWVNEVLGPELPKCVP-VCGVPREPFEE 143 Score = 48.4 bits (113), Expect = 2e-05, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 46/142 (32%), Gaps = 22/142 (15%) Query: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLK----GSSQI--RCKADNTWDPEIP 655 C N +A Y + D V C GF + G++ C+++ W Sbjct: 3 CPKEDTPNSVWE-PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 656 VCEKETCQHVRQ----SLQELPAGSRVELVNTSCQDGYQLT---GHAYQMCQDAENGIWF 708 C+ C +++ + ++ +C++ Y G C NG W Sbjct: 62 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAG--NGSWV 119 Query: 709 -----KKIPLCKVIHCHPPPVI 725 ++P C + C P Sbjct: 120 NEVLGPELPKCVPV-CGVPREP 140 Score = 46.1 bits (107), Expect = 8e-05, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 38/143 (26%), Gaps = 10/143 (6%) Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ----GPPSSRCVIAGQGVAWTKMPV 270 C + C +G+ + G S G Sbjct: 3 CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLK 62 Query: 271 CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQ 330 C+ + C P I NG+ GS++ YTC+ N G C + Sbjct: 63 CQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMEN---GGGGEYHCAGNGS 117 Query: 331 KTGTWSGPA-PRCELSTSAVQCP 352 GP P+C + P Sbjct: 118 WVNEVLGPELPKCVPVCGVPREP 140 Score = 37.2 bits (84), Expect = 0.038, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 18 VLGISCGSPPPILNGRI-SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD 76 + CG P I NG++ ST G+VIRY+C + + +G+W Sbjct: 63 CQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGG-GGEYHCAGNGSWV 119 Query: 77 KPAPKCEYFNKYSSCPEPIVPGGYKIR 103 E C P P K R Sbjct: 120 NEVLGPELPKCVPVCGVPREPFEEKAR 146 >4LOT-A nrPDB Length = 249 Score = 103 bits (255), Expect = 5e-22, Method: Composition-based stats. Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 18/133 (13%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK------GSKQIRCNAQGTWEPSAP 404 CP + K +Y + D V C+ GF + S C + G W S Sbjct: 120 CPKEDTP-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 178 Query: 405 VCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT 460 C+ +C P +I NG+ ED F G+ I+Y+C Y + G C G W Sbjct: 179 KCQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWV 236 Query: 461 -----PPVPQCKV 468 P +P+C Sbjct: 237 NEVLGPELPKCVP 249 Score = 64.9 bits (156), Expect = 2e-10, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 44/134 (32%), Gaps = 19/134 (14%) Query: 852 PPPPKTPNGNHTG---GNIARFSPGMSILYSCDQGYLLVGEA------LLLCTHEGTWSQ 902 P P A++ + +C G+ +V C G WS Sbjct: 116 DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSN 175 Query: 903 PAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE---GSPQSQCQSDH 959 C+ V+C P ++ + E + +G+V+ CE+ Y G + C + Sbjct: 176 SKLKCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNG 233 Query: 960 QW-----NPPLAVC 968 W P L C Sbjct: 234 SWVNEVLGPELPKC 247 Score = 56.5 bits (134), Expect = 7e-08, Method: Composition-based stats. Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 20/136 (14%) Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFS----MNGNKSVW--CQANNMWGPTRLP 144 CP+ P Y D V C F G S + CQ+N W Sbjct: 120 CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS----N 175 Query: 145 TCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV---GEKIINCLSSG 201 + + P++C I NG E+ S G + Y+CE Y + G +C +G Sbjct: 176 SKLKCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNG 233 Query: 202 KW-----SAVPPTCEE 212 W P C Sbjct: 234 SWVNEVLGPELPKCVP 249 Score = 56.1 bits (133), Expect = 8e-08, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 12/127 (9%) Query: 664 HVRQSLQELPAGSRV--ELVNTSCQDGYQLT----GHAYQMCQDAENGIWFKKIPLCKVI 717 S+ E V ++V +C DG+++ G NG W C+ + Sbjct: 124 DTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPV 183 Query: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSWSG 774 C P I NGK E+ L+G+ + Y C++ +Y + G + C + G Sbjct: 184 DCGIPESIENGKVEDP--ESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLG 241 Query: 775 PS-PQCL 780 P P+C+ Sbjct: 242 PELPKCV 248 Score = 55.3 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 41/122 (33%), Gaps = 11/122 (9%) Query: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI------INCLSSGKWS 204 P+ CP N V +C G+ +V ++ C S+GKWS Sbjct: 117 PMPCPK-EDTPNSVWEPAK-AKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 174 Query: 205 AVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ---GPPSSRCVIAGQ 261 C+ C NGKV++P G + C+E Y G C G Sbjct: 175 NSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGS 234 Query: 262 GV 263 V Sbjct: 235 WV 236 Score = 52.2 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 36/113 (31%), Gaps = 12/113 (10%) Query: 488 RPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541 R V +C +G+++ S Y CQ W C+ + C P I NG Sbjct: 140 RDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDP 199 Query: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPA-PLC 593 F G+ + YTC G C N GP P C Sbjct: 200 ESTLF--GSVIRYTCEEPYYYMEN---GGGGEYHCAGNGSWVNEVLGPELPKC 247 Score = 51.1 bits (120), Expect = 3e-06, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 42/136 (30%), Gaps = 15/136 (11%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP E + Y D+V + C GF + RV C ++ W Sbjct: 120 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 178 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV---GEALLLCTHEG 898 C + C P NG F G I Y+C++ Y + G C G Sbjct: 179 KCQP---VDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNG 233 Query: 899 TWSQPAPHCKEVNCSS 914 +W + C Sbjct: 234 SWVNEVLGPELPKCVP 249 Score = 49.9 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 39/119 (32%), Gaps = 17/119 (14%) Query: 423 DRHMVRFDPGTSIKYSCNPGYVLV----GEESI--QCTSEGVWTPPVPQCKVAAC---EA 473 + ++ ++ +C G+ +V G S C S G W+ +C+ C E+ Sbjct: 131 EPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPES 190 Query: 474 TGRQLLTKPQHQFVRPDVNSSCGEGYKLS---GSVYQECQGTIPW-----FMEIRLCKE 524 + P+ + +C E Y G C G W E+ C Sbjct: 191 IENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVP 249 Score = 47.6 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 42/145 (28%), Gaps = 21/145 (14%) Query: 524 EITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 583 + CP + + + + V TC G E C SN Sbjct: 117 PMPCPKEDTPNS--VWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSN---- 170 Query: 584 GTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLK---GS 639 G WS C+ V C I NG + + + + C + G Sbjct: 171 GKWSNSKLKCQ----PVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGG 224 Query: 640 SQIRCKADNTW-----DPEIPVCEK 659 + C + +W PE+P C Sbjct: 225 GEYHCAGNGSWVNEVLGPELPKCVP 249 Score = 44.9 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 39/146 (26%), Gaps = 10/146 (6%) Query: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ----GPPSSRCV 257 K + + C + C +G+ + G S Sbjct: 107 KGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYST 166 Query: 258 IAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFIL 317 G C+ + C P I NG+ GS++ YTC+ N Sbjct: 167 CQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMEN--- 221 Query: 318 IGESTLRCTVDSQKTGTWSGPA-PRC 342 G C + GP P+C Sbjct: 222 GGGGEYHCAGNGSWVNEVLGPELPKC 247 Score = 43.4 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 21/131 (16%) Query: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLK----GSSQI--RCKADNTWDPEIP 655 C N +A Y + D V C GF + G++ C+++ W Sbjct: 120 CPKEDTPNSVWE-PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 178 Query: 656 VCEKETCQHVRQ----SLQELPAGSRVELVNTSCQDGYQLT---GHAYQMCQDAENGIWF 708 C+ C +++ + ++ +C++ Y G C NG W Sbjct: 179 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAG--NGSWV 236 Query: 709 -----KKIPLC 714 ++P C Sbjct: 237 NEVLGPELPKC 247 Score = 42.6 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 42/122 (34%), Gaps = 17/122 (13%) Query: 906 HCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE----GSPQS--QCQSDH 959 H + C + + + + Y + VV + C DG+ + G+ CQS+ Sbjct: 114 HGDPMPCPKEDTPNSVWE--PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 171 Query: 960 QWNPPLAVCRSRSLAPVLCGIAA----GLILLTFLIVITLYVISKHRARNYYTDTSQKEA 1015 +W+ C+ PV CGI G + + + YY + Sbjct: 172 KWSNSKLKCQ-----PVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGE 226 Query: 1016 FH 1017 +H Sbjct: 227 YH 228 Score = 32.2 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 28/71 (39%), Gaps = 9/71 (12%) Query: 18 VLGISCGSPPPILNGRI-SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD 76 + CG P I NG++ ST G+VIRY+C + + +G+W Sbjct: 180 CQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGG-GGEYHCAGNGSWV 236 Query: 77 KPA-----PKC 82 PKC Sbjct: 237 NEVLGPELPKC 247 >5UBM-B nrPDB Length = 152 Score = 97.3 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 35/134 (26%), Positives = 51/134 (38%), Gaps = 18/134 (13%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK------GSKQIRCNAQGTWEPSAP 404 CP + K +Y + D V C+ GF + S C + G W S Sbjct: 10 CPKEDTP-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 68 Query: 405 VCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT 460 C+ +C P +I NG+ ED F G+ I+Y+C Y + G C G W Sbjct: 69 KCQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWV 126 Query: 461 -----PPVPQCKVA 469 P +P+C Sbjct: 127 NEVLGPELPKCVPV 140 Score = 64.2 bits (154), Expect = 3e-10, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 47/141 (33%), Gaps = 15/141 (10%) Query: 852 PPPPKTPNGNHTG---GNIARFSPGMSILYSCDQGYLLVGEA------LLLCTHEGTWSQ 902 P P A++ + +C G+ +V C G WS Sbjct: 6 DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSN 65 Query: 903 PAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE---GSPQSQCQSDH 959 C+ V+C P ++ + E + +G+V+ CE+ Y G + C + Sbjct: 66 SKLKCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNG 123 Query: 960 QWNPPLAVCRSRSLAPVLCGI 980 W + + +CG+ Sbjct: 124 SWVNEV-LGPELPKCVPVCGV 143 Score = 53.8 bits (127), Expect = 4e-07, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 21/145 (14%) Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFS----MNGNKSVW--CQANNMWGPTRLP 144 CP+ P Y D V C F G S + CQ+N W Sbjct: 10 CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS----N 65 Query: 145 TCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV---GEKIINCLSSG 201 + + P++C I NG E+ S G + Y+CE Y + G +C +G Sbjct: 66 SKLKCQPVDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNG 123 Query: 202 KW-----SAVPPTCEEARCKSLGRF 221 W P C C Sbjct: 124 SWVNEVLGPELPKCVPV-CGVPREP 147 Score = 53.8 bits (127), Expect = 4e-07, Method: Composition-based stats. Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 17/138 (12%) Query: 664 HVRQSLQELPAGSRV--ELVNTSCQDGYQLT----GHAYQMCQDAENGIWFKKIPLCKVI 717 S+ E V ++V +C DG+++ G NG W C+ + Sbjct: 14 DTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPV 73 Query: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSWSG 774 C P I NGK E+ L+G+ + Y C++ +Y + G + C + GSW Sbjct: 74 DCGIPESIENGKVEDP--ESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGN----GSWVN 127 Query: 775 PS--PQCLRSPPVTRCPN 790 P+ + PV P Sbjct: 128 EVLGPELPKCVPVCGVPR 145 Score = 52.2 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 43/122 (35%), Gaps = 13/122 (10%) Query: 173 IAPGLSVTYSCESGYLLVGEKI------INCLSSGKWSAVPPTCEEARCKSLGRFPNGKV 226 V +C G+ +V ++ C S+GKWS C+ C NGKV Sbjct: 27 YVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKV 86 Query: 227 KEPPILRVGVTANFFCDEGYRLQ---GPPSSRCVIAGQGVAWT---KMPVCEEIFCPSPP 280 ++P G + C+E Y G C G V ++P C + C P Sbjct: 87 EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPV-CGVPR 145 Query: 281 PI 282 Sbjct: 146 EP 147 Score = 48.8 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 36/113 (31%), Gaps = 12/113 (10%) Query: 488 RPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541 R V +C +G+++ S Y CQ W C+ + C P I NG Sbjct: 30 RDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDP 89 Query: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPA-PLC 593 F G+ + YTC G C N GP P C Sbjct: 90 ESTLF--GSVIRYTCEEPYYYMEN---GGGGEYHCAGNGSWVNEVLGPELPKC 137 Score = 48.4 bits (113), Expect = 2e-05, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 21/145 (14%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP E + Y D+V + C GF + RV C ++ W Sbjct: 10 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 68 Query: 842 TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV---GEALLLCTHEG 898 C + C P NG F G I Y+C++ Y + G C G Sbjct: 69 KCQP---VDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNG 123 Query: 899 TWSQ-----PAPHCKEVNCSSPADM 918 +W P C V C P + Sbjct: 124 SWVNEVLGPELPKCVPV-CGVPREP 147 Score = 47.6 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 40/128 (31%), Gaps = 18/128 (14%) Query: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEE------SIQCTSEGVWTPPVPQCKVAAC---EA 473 + ++ ++ +C G+ +V C S G W+ +C+ C E+ Sbjct: 21 EPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPES 80 Query: 474 TGRQLLTKPQHQFVRPDVNSSCGEGYKLS---GSVYQECQGTIPW-----FMEIRLCKEI 525 + P+ + +C E Y G C G W E+ C + Sbjct: 81 IENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPV 140 Query: 526 TCPPPPVI 533 C P Sbjct: 141 -CGVPREP 147 Score = 46.4 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 45/150 (30%), Gaps = 19/150 (12%) Query: 277 PSPPPILNGRHI--GNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGT 334 P P P + + + A + +V TC E + C Q G Sbjct: 7 PMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTC----QSNGK 62 Query: 335 WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK---GSKQI 391 WS +C+ V C P+ + V + + + + C + G + Sbjct: 63 WSNSKLKCQ----PVDCGIPESIENGKVEDPEST-LFGSVIRYTCEEPYYYMENGGGGEY 117 Query: 392 RCNAQGTW-----EPSAPVCEKECQAPPNI 416 C G+W P P C C P Sbjct: 118 HCAGNGSWVNEVLGPELPKCVPVCGVPREP 147 Score = 43.7 bits (101), Expect = 5e-04, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 47/157 (29%), Gaps = 22/157 (14%) Query: 524 EITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 583 + CP + + + + V TC G E C SN Sbjct: 7 PMPCPKEDTPNS--VWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSN---- 60 Query: 584 GTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLK---GS 639 G WS C+ V C I NG + + + + C + G Sbjct: 61 GKWSNSKLKCQ----PVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGG 114 Query: 640 SQIRCKADNTW-----DPEIPVCEKETCQHVRQSLQE 671 + C + +W PE+P C C R+ +E Sbjct: 115 GEYHCAGNGSWVNEVLGPELPKCVP-VCGVPREPFEE 150 Score = 42.2 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 39/147 (26%), Gaps = 10/147 (6%) Query: 211 EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ----GPPSSRCVIAGQGVAWT 266 + C + C +G+ + G S G Sbjct: 6 DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSN 65 Query: 267 KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326 C+ + C P I NG+ GS++ YTC+ N G C Sbjct: 66 SKLKCQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMEN---GGGGEYHCA 120 Query: 327 VDSQKTGTWSGPA-PRCELSTSAVQCP 352 + GP P+C + P Sbjct: 121 GNGSWVNEVLGPELPKCVPVCGVPREP 147 Score = 41.1 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 44/129 (34%), Gaps = 21/129 (16%) Query: 615 GKEAPYFYNDTVTFKCYSGFTLK----GSSQI--RCKADNTWDPEIPVCEKETCQHVRQ- 667 +A Y + D V C GF + G++ C+++ W C+ C Sbjct: 22 PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESI 81 Query: 668 ---SLQELPAGSRVELVNTSCQDGYQLT---GHAYQMCQDAENGIWF-----KKIPLCKV 716 +++ + ++ +C++ Y G C NG W ++P C Sbjct: 82 ENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAG--NGSWVNEVLGPELPKCVP 139 Query: 717 IHCHPPPVI 725 + C P Sbjct: 140 V-CGVPREP 147 Score = 33.0 bits (73), Expect = 0.79, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 18 VLGISCGSPPPILNGRI-SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD 76 + CG P I NG++ ST G+VIRY+C + + +G+W Sbjct: 70 CQPVDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGG-GGEYHCAGNGSWV 126 Query: 77 KPAPKCEYFNKYSSCPEPIVPGGYK 101 E C P P K Sbjct: 127 NEVLGPELPKCVPVCGVPREPFEEK 151 >1GPZ-A nrPDB Length = 399 Score = 78.8 bits (192), Expect = 1e-14, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 48/151 (31%), Gaps = 21/151 (13%) Query: 849 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEA-----LLLCTHEGTWSQ 902 I CP P ++ + +C QGY L+ G +C +GTW + Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 903 PAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLE----GS-----PQ 952 P CK +C P + +G + + Y A + C + Y GS Sbjct: 61 AMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGV 120 Query: 953 SQCQSDHQWNPP-----LAVCRSRSLAPVLC 978 C + W + C PV Sbjct: 121 YTCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 151 Score = 76.5 bits (186), Expect = 5e-14, Method: Composition-based stats. Identities = 37/162 (22%), Positives = 60/162 (37%), Gaps = 27/162 (16%) Query: 349 VQCPHPQILRGR-MVSGQKDRYTYNDTVIFACMFGFTLKG------SKQIRCNAQGTWEP 401 ++CP P+ L ++ + +Y + D I C G+ L S C GTW Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 402 SAPVCE-KECQAPPNILNGQ-KEDRHMVRFDPGTSIKYSCNPGYVLVGEES--------- 450 + P C+ K+C P N+ NG + M I+Y C+ Y + + Sbjct: 61 AMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGV 120 Query: 451 IQCTSEGVWTPP---------VPQCKVAACEATGRQLLTKPQ 483 CT++G+W +P C RQ + Q Sbjct: 121 YTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQQIIGGQ 162 Score = 58.8 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 41/221 (18%), Positives = 68/221 (30%), Gaps = 32/221 (14%) Query: 786 TRCPNPEVKHGYKLNKT-HSAYSHNDIVYVDCNPGFIMNGSR------VIRCHTDNTWVP 838 +CP P+ + + + Y D C G+ + C D TW Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 839 GVPTCIKKAFIGCPPPPKTPNGNHTG-GNIARFSPGMSILYSCDQGYLLVGEA------- 890 +P C K C P PNG+ + + I Y C + Y + Sbjct: 61 AMPRCKIK---DCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESE 117 Query: 891 --LLLCTHEGTWSQ-----PAPHCKEVNCSSPADM-DGIQKGLEPR----KMYQYGAVVT 938 + CT +G W P C V C P + + Q+ + + + + Sbjct: 118 QGVYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTN 176 Query: 939 LECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979 + G L G + + H P +S + V G Sbjct: 177 IHGRGGGALLGD-RWILTAAHTLYPKEHEAQSNASLDVFLG 216 Score = 56.1 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 47/157 (29%), Gaps = 20/157 (12%) Query: 274 IFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTG 333 I CP P + I N + TC + ++ T C D G Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDD----G 56 Query: 334 TWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGF----TLKGSK 389 TW PRC++ P + TY + + C + T GS+ Sbjct: 57 TWHRAMPRCKI--KDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSR 114 Query: 390 -----QIRCNAQGTWEPS-----APVCEKECQAPPNI 416 C AQG W+ P C C P N Sbjct: 115 ESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 151 Score = 53.8 bits (127), Expect = 4e-07, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 45/156 (28%), Gaps = 22/156 (14%) Query: 152 LECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEK-----IINCLSSGKWSA 205 ++CP + +C+ GY L+ G + C G W Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 206 VPPTCEEARCKSLGRFPNGKVKEPPILRVGV---TANFFCDEGYRLQ----GPPSS---- 254 P C+ C PNG + + V ++C E Y G S Sbjct: 61 AMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGV 120 Query: 255 -RCVIAGQG---VAWTKMPVCEEIFCPSPPPILNGR 286 C G K+P C + C P + R Sbjct: 121 YTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQR 155 Score = 53.4 bits (126), Expect = 6e-07, Method: Composition-based stats. Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 23/137 (16%) Query: 673 PAGSRVELVNTSCQDGYQLT-GHA-----YQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726 P + +C+ GYQL G+ +CQD G W + +P CK+ C P + Sbjct: 20 PQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDD--GTWHRAMPRCKIKDCGQPRNLP 77 Query: 727 NG--KHTGMMAENFLYGNEVSYECDQGFYLL-----GEKKLQCRSDSKGHGSWSGP---- 775 NG ++T M N Y + Y C + +Y + + Q G W Sbjct: 78 NGDFRYTTTMGVN-TYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGE 136 Query: 776 -SPQCLRSPPVTRCPNP 791 P+CL P + NP Sbjct: 137 KIPRCL--PVCGKPVNP 151 Score = 48.4 bits (113), Expect = 2e-05, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 49/160 (30%), Gaps = 35/160 (21%) Query: 600 VQCSHVHIANGY-KISGKEAPYFYNDTVTFKCYSGFTL-KGSS-----QIRCKADNTWDP 652 ++C + + I + Y + D C G+ L +G+ C+ D TW Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 653 EIPVCEKETCQHVRQSLQELPAGSR-----------VELVNTSCQDGYQ-------LTGH 694 +P C+ + C R LP G + C + Y Sbjct: 61 AMPRCKIKDCGQPRN----LPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRES 116 Query: 695 AYQMCQDAENGIWFK-----KIPLCKVIHCHPPPVIVNGK 729 + GIW KIP C + C P V + Sbjct: 117 EQGVYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQR 155 Score = 47.6 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 44/153 (28%), Gaps = 31/153 (20%) Query: 409 ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE------SIQCTSEGVWTPP 462 +C P + ++ +C GY L+ + C +G W Sbjct: 2 KCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 61 Query: 463 VPQCKVAACEATGRQLLTKPQHQF--------VRPDVNSSCGEGYKLS----GSVYQE-- 508 +P+CK+ C + L ++ + + C E Y GS E Sbjct: 62 MPRCKIKDCGQP--RNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQG 119 Query: 509 ---CQGTIPWFME-----IRLCKEITCPPPPVI 533 C W E I C + C P Sbjct: 120 VYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNP 151 Score = 46.4 bits (108), Expect = 7e-05, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 56/171 (32%), Gaps = 26/171 (15%) Query: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584 I CP P + + + + TC G + ++ T C Q+ G Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVC----QDDG 56 Query: 585 TWSGPAPLCKLSLLAVQCSHV-HIANG-YKISGKEAPYFYNDTVTFKCYSGFTLK----G 638 TW P CK+ C ++ NG ++ + Y + + C+ + G Sbjct: 57 TWHRAMPRCKI----KDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAG 112 Query: 639 SSQI-----RCKADNTWDPE-----IPVCEK--ETCQHVRQSLQELPAGSR 677 S + C A W E IP C + + Q++ G + Sbjct: 113 SRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQQIIGGQK 163 Score = 44.5 bits (103), Expect = 3e-04, Method: Composition-based stats. Identities = 31/171 (18%), Positives = 54/171 (31%), Gaps = 22/171 (12%) Query: 469 AACEATGRQLL------TKPQHQFVRPDVNSSCGEGYKL-SGSV-----YQECQGTIPWF 516 C +PQ+QF R ++C +GY+L G+ CQ W Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQF-RDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWH 59 Query: 517 MEIRLCKEITCPPPPVIYNGAHTGSSLEDF-PYGTTVTYTCNPGPERGVEFSLIGESTIR 575 + CK C P + NG ++ Y + Y C+ P ++ + + Sbjct: 60 RAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHE-PYYKMQTRAGSRESEQ 118 Query: 576 CTSNDQERGTWSGP-----APLCKLSLLAVQCSHVHIANGYKISGKEAPYF 621 +G W P C + + + I G++A Sbjct: 119 GVYTCTAQGIWKNEQKGEKIPRC--LPVCGKPVNPVEQRQQIIGGQKAKMG 167 >1Q3X-A nrPDB Length = 328 Score = 76.5 bits (186), Expect = 6e-14, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 909 EVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDHQWNPPL 965 V+C P D G + + + Y AV+ CE+ + M + C++D W Sbjct: 5 IVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSK 64 Query: 966 AVCRSRSLAPVLCGIAA 982 +S + +CG++A Sbjct: 65 GE-KSLPVCEPVCGLSA 80 Score = 38.4 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 28/84 (33%), Gaps = 3/84 (3%) Query: 409 ECQAPPNILNGQKEDRHMVRFD-PGTSIKYSCNPGYVLV--GEESIQCTSEGVWTPPVPQ 465 +C P ++ +G+ E I+YSC + + + C ++G WT + Sbjct: 7 DCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGE 66 Query: 466 CKVAACEATGRQLLTKPQHQFVRP 489 + CE + Sbjct: 67 KSLPVCEPVCGLSARTTGGRIYGG 90 Score = 36.4 bits (82), Expect = 0.066, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 14/99 (14%) Query: 21 ISCGSPPPILNGRISYYSTP--IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW--- 75 + CG P + +GR+ Y + P VI+YSC TF + K + DG W Sbjct: 6 VDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTM--KVNDGKYVCEADGFWTSS 63 Query: 76 --DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGD 112 +K P CE C G +I G + GD Sbjct: 64 KGEKSLPVCEPV-----CGLSARTTGGRIYGGQKAKPGD 97 >4AQB-A nrPDB Length = 361 Score = 72.6 bits (176), Expect = 8e-13, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 346 TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL------KGSKQIRCNAQGTW 399 + +CP Q + + +Y + D V+ +C G+ + + QI C GTW Sbjct: 277 AAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTW 336 Query: 400 EPSAPVCEK 408 P C+K Sbjct: 337 SNKIPTCKK 345 Score = 45.7 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 7/71 (9%) Query: 845 KKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL------LLCTHEG 898 + A CP +G + A++ +L SCD GY ++ + + + C +G Sbjct: 276 RAAGNECPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG 334 Query: 899 TWSQPAPHCKE 909 TWS P CK+ Sbjct: 335 TWSNKIPTCKK 345 Score = 45.7 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTL------KGSSQIRCKADNTWDPEI 654 +C + KI +A YF+ D V C +G+ + + QI C D TW +I Sbjct: 281 ECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKI 340 Query: 655 PVCEK 659 P C+K Sbjct: 341 PTCKK 345 Score = 43.4 bits (100), Expect = 6e-04, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 20/44 (45%), Gaps = 4/44 (9%) Query: 676 SRVELVNTSCQDGYQLTGHAYQM----CQDAENGIWFKKIPLCK 715 + V SC GY++ +M + ++G W KIP CK Sbjct: 301 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK 344 Score = 43.0 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 394 NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE---- 449 W S EC ++G+ E ++ + SC+ GY ++ + Sbjct: 266 GENRGWRLSYRAAGNECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMD 324 Query: 450 --SIQCTSEGVWTPPVPQCKV 468 I+C +G W+ +P CK Sbjct: 325 TFQIECLKDGTWSNKIPTCKK 345 Score = 39.1 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 7/70 (10%) Query: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI------INCLSSGKWSAV 206 ECP L +G V SC++GY ++ + + I CL G WS Sbjct: 281 ECPELQPPVHGKIEPSQ-AKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 339 Query: 207 PPTCEEARCK 216 PTC++ Sbjct: 340 IPTCKKNEID 349 Score = 36.8 bits (83), Expect = 0.051, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP + K+ + + Y D V V C+ G+ + V I C D TW +P Sbjct: 282 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP 341 Query: 842 TCIK 845 TC K Sbjct: 342 TCKK 345 Score = 35.3 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 19/50 (38%), Gaps = 6/50 (12%) Query: 926 EPRKMYQYGAVVTLECEDGYMLEGSP------QSQCQSDHQWNPPLAVCR 969 + Y + V + C+ GY + Q +C D W+ + C+ Sbjct: 295 PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK 344 Score = 34.9 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 26/66 (39%), Gaps = 3/66 (4%) Query: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGF--YLLGEKKLQCRSDSKGHGSWSGP 775 C V+GK A+ F + ++V CD G+ + + + G+WS Sbjct: 281 ECPELQPPVHGKIEPSQAKYF-FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 339 Query: 776 SPQCLR 781 P C + Sbjct: 340 IPTCKK 345 Score = 33.3 bits (74), Expect = 0.51, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P ++G+ I S A + V +CD + + + + + C D GTW Sbjct: 282 CPELQPPVHGK-IEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKD----GTW 336 Query: 336 SGPAPRCEL 344 S P C+ Sbjct: 337 SNKIPTCKK 345 Score = 32.6 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 19/58 (32%), Gaps = 6/58 (10%) Query: 472 EATGRQLLTKPQHQFVRPDVNSSCGEGYKL------SGSVYQECQGTIPWFMEIRLCK 523 ++ F + V SC GYK+ + EC W +I CK Sbjct: 287 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK 344 Score = 32.6 bits (72), Expect = 0.87, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%), Gaps = 5/68 (7%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP +G S + + V +C+ G + + + I C + GTW Sbjct: 282 CPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIEC----LKDGTW 336 Query: 587 SGPAPLCK 594 S P CK Sbjct: 337 SNKIPTCK 344 Score = 31.8 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 26/66 (39%), Gaps = 2/66 (3%) Query: 20 GISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDK--VDGTWDK 77 G C P ++G+I + SC ++++ + + + + DGTW Sbjct: 279 GNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSN 338 Query: 78 PAPKCE 83 P C+ Sbjct: 339 KIPTCK 344 >2QY0-A nrPDB Length = 159 Score = 70.3 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 46/150 (30%), Gaps = 21/150 (14%) Query: 850 GCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEA-----LLLCTHEGTWSQP 903 CP P ++ + +C QGY L+ G +C +GTW + Sbjct: 4 ACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 63 Query: 904 APHCKEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS---------PQS 953 P CK +C P + +G + + Y A + C + Y + Sbjct: 64 MPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVY 123 Query: 954 QCQSDHQWNPP-----LAVCRSRSLAPVLC 978 C + W + C PV Sbjct: 124 TCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 153 Score = 67.6 bits (163), Expect = 3e-11, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 56/150 (37%), Gaps = 18/150 (12%) Query: 350 QCPHPQILRGR-MVSGQKDRYTYNDTVIFACMFGFTLKG------SKQIRCNAQGTWEPS 402 CP P+ L ++ + +Y + D I C G+ L S C GTW + Sbjct: 4 ACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 63 Query: 403 APVCE-KECQAPPNILNGQ-KEDRHMVRFDPGTSIKYSCNPGYVLVGEES---------I 451 P C+ K+C P N+ NG + M I+Y C+ Y + + Sbjct: 64 MPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVY 123 Query: 452 QCTSEGVWTPPVPQCKVAACEATGRQLLTK 481 CT++G+W K+ C + + Sbjct: 124 TCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 153 Score = 50.3 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 47/153 (30%), Gaps = 26/153 (16%) Query: 788 CPNPEVKHGYKLNKT-HSAYSHNDIVYVDCNPGFIMNGSR------VIRCHTDNTWVPGV 840 CP P+ + + + Y D C G+ + C D TW + Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 64 Query: 841 PTCIKKAFIGCPPPPKTPNGNHTG-GNIARFSPGMSILYSCDQGYLLVGEA--------- 890 P C K C P PNG+ + + I Y C + Y + Sbjct: 65 PRCKIK---DCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQG 121 Query: 891 LLLCTHEGTWSQ-----PAPHCKEVNCSSPADM 918 + CT +G W P C V C P + Sbjct: 122 VYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNP 153 Score = 48.8 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 44/155 (28%), Gaps = 20/155 (12%) Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335 CP P + I N + TC + ++ T C D GTW Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDD----GTW 60 Query: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSK------ 389 PRC++ P + TY + + C + ++ Sbjct: 61 HRAMPRCKI--KDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRES 118 Query: 390 ---QIRCNAQGTWEPS-----APVCEKECQAPPNI 416 C AQG W+ P C C P N Sbjct: 119 EQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 153 Score = 47.2 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 43/154 (27%), Gaps = 22/154 (14%) Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEK-----IINCLSSGKWSAVP 207 CP + +C+ GY L+ G + C G W Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 64 Query: 208 PTCEEARCKSLGRFPNGKVKEPPILRVGV---TANFFCDEGYRLQ----GPPSS-----R 255 P C+ C PNG + + V ++C E Y G S Sbjct: 65 PRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYT 124 Query: 256 CVIAGQG---VAWTKMPVCEEIFCPSPPPILNGR 286 C G K+P C + C P + R Sbjct: 125 CTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQR 157 Score = 46.8 bits (109), Expect = 5e-05, Method: Composition-based stats. Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 19/135 (14%) Query: 673 PAGSRVELVNTSCQDGYQLT-GHAYQ---MCQDAENGIWFKKIPLCKVIHCHPPPVIVNG 728 P + +C+ GYQL G+ ++G W + +P CK+ C P + NG Sbjct: 22 PQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNG 81 Query: 729 --KHTGMMAENFLYGNEVSYECDQGFYLL-----GEKKLQCRSDSKGHGSWSGP-----S 776 ++T M N Y + Y C + +Y + + Q G W Sbjct: 82 DFRYTTTMGVN-TYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKI 140 Query: 777 PQCLRSPPVTRCPNP 791 P+CL P + NP Sbjct: 141 PRCL--PVCGKPVNP 153 Score = 41.1 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 27/152 (17%), Positives = 43/152 (28%), Gaps = 31/152 (20%) Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE------SIQCTSEGVWTPPV 463 C P + ++ +C GY L+ + C +G W + Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 64 Query: 464 PQCKVAACEATGRQLLTKPQHQF--------VRPDVNSSCGEGYKLS----GSVYQE--- 508 P+CK+ C + L ++ + + C E Y GS E Sbjct: 65 PRCKIKDCGQP--RNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGV 122 Query: 509 --CQGTIPWFME-----IRLCKEITCPPPPVI 533 C W E I C + C P Sbjct: 123 YTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNP 153 Score = 40.7 bits (93), Expect = 0.004, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 48/155 (30%), Gaps = 27/155 (17%) Query: 601 QCSHVHIANGY-KISGKEAPYFYNDTVTFKCYSGFTL-KGSS-----QIRCKADNTWDPE 653 C + + I + Y + D C G+ L +G+ C+ D TW Sbjct: 4 ACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 63 Query: 654 IPVCEKETCQHVRQ-SLQELPAGSRVELVNTSCQDGYQLTGHAYQM-------------C 699 +P C+ + C R + + + + + Y Y+M Sbjct: 64 MPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVY 123 Query: 700 QDAENGIWFK-----KIPLCKVIHCHPPPVIVNGK 729 GIW KIP C + C P V + Sbjct: 124 TCTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQR 157 Score = 39.9 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 8/85 (9%) Query: 481 KPQHQFVRPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEIRLCKEITCPPPPVIY 534 +PQ+QF R ++C +GY+L S CQ W + CK C P + Sbjct: 21 QPQYQF-RDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLP 79 Query: 535 NGAHTGSSLEDF-PYGTTVTYTCNP 558 NG ++ Y + Y C+ Sbjct: 80 NGDFRYTTTMGVNTYKARIQYYCHE 104 Score = 36.8 bits (83), Expect = 0.047, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 52/161 (32%), Gaps = 25/161 (15%) Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586 CP P + + + + TC G + ++ T C Q+ GTW Sbjct: 5 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVC----QDDGTW 60 Query: 587 SGPAPLCKLSLLAVQCSHV-HIANG-YKISGKEAPYFYNDTVTFKCYSGFTLK----GSS 640 P CK+ C ++ NG ++ + Y + + C+ + GS Sbjct: 61 HRAMPRCKI----KDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSR 116 Query: 641 QI-----RCKADNTWDPE-----IPVCEKETCQHVRQSLQE 671 + C A W E IP C C +++ Sbjct: 117 ESEQGVYTCTAQGIWKNEQKGEKIPRCLP-VCGKPVNPVEQ 156 >3TVJ-A nrPDB Length = 86 Score = 65.7 bits (158), Expect = 9e-11, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Query: 909 EVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGY--MLEGSPQSQCQSDHQWNPPL 965 V+C P D G + + + Y AV+ CE+ + M + C +D W Sbjct: 5 IVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCDADGFWTSSK 64 Query: 966 AVCRSRSLAPVLCGIAA 982 +S + +CG++A Sbjct: 65 GE-KSLPVCEPVCGLSA 80 Score = 32.6 bits (72), Expect = 1.0, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 409 ECQAPPNILNGQKEDRHMVRFD-PGTSIKYSCNPGYVLV--GEESIQCTSEGVWTPPVPQ 465 +C P ++ +G+ E I+YSC + + + C ++G WT + Sbjct: 7 DCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCDADGFWTSSKGE 66 Query: 466 CKVAACEATG 475 + CE Sbjct: 67 KSLPVCEPVC 76 >1ELV-A nrPDB Length = 333 Score = 64.5 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 35/91 (38%), Gaps = 12/91 (13%) Query: 409 ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---GEESIQCTSEGVWT----- 460 +C P +I NG+ ED F G+ I+Y+C Y + G C G W Sbjct: 3 DCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLG 60 Query: 461 PPVPQCKVAACEATGRQLLTKPQHQFVRPDV 491 P +P+C C R+ + Q D Sbjct: 61 PELPKCVPV-CGVP-REPFEEKQRIIGGSDA 89 Score = 42.6 bits (98), Expect = 0.001, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 30/75 (40%), Gaps = 6/75 (8%) Query: 909 EVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE---GSPQSQCQSDHQWNPPL 965 +++C P ++ + E + +G+V+ CE+ Y G + C + W + Sbjct: 1 DLDCGIPESIENGKV--EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEV 58 Query: 966 AVCRSRSLAPVLCGI 980 + +CG+ Sbjct: 59 -LGPELPKCVPVCGV 72 Score = 40.3 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 22/74 (29%), Gaps = 9/74 (12%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK---GSKQIRCNAQGTW-----EPS 402 C P+ + V + + + + C + G + C G+W P Sbjct: 4 CGIPESIENGKVEDPEST-LFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPE 62 Query: 403 APVCEKECQAPPNI 416 P C C P Sbjct: 63 LPKCVPVCGVPREP 76 Score = 39.1 bits (89), Expect = 0.011, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 11/80 (13%) Query: 716 VIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL---GEKKLQCRSDSKGHGSW 772 + C P I NGK E+ L+G+ + Y C++ +Y + G + C + GSW Sbjct: 1 DLDCGIPESIENGKVEDP--ESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGN----GSW 54 Query: 773 SGPS--PQCLRSPPVTRCPN 790 P+ + PV P Sbjct: 55 VNEVLGPELPKCVPVCGVPR 74 Score = 36.8 bits (83), Expect = 0.050, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 25/74 (33%), Gaps = 7/74 (9%) Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ---GPPSSRCVIAGQGVAWT---KM 268 C NGKV++P G + C+E Y G C G V ++ Sbjct: 4 CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPEL 63 Query: 269 PVCEEIFCPSPPPI 282 P C + C P Sbjct: 64 PKCVPV-CGVPREP 76 Score = 34.1 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 4/84 (4%) Query: 21 ISCGSPPPILNGRI-SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPA 79 + CG P I NG++ ST G+VIRY+C + + +G+W Sbjct: 2 LDCGIPESIENGKVEDPESTLF--GSVIRYTCEEPYYYMENGG-GGEYHCAGNGSWVNEV 58 Query: 80 PKCEYFNKYSSCPEPIVPGGYKIR 103 E C P P K R Sbjct: 59 LGPELPKCVPVCGVPREPFEEKQR 82 >4LOS-A nrPDB Length = 187 Score = 55.3 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 22/65 (33%), Gaps = 7/65 (10%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK------GSKQIRCNAQGTWEPSAP 404 CP + K +Y + D V C+ GF + S C + G W S Sbjct: 123 CPKEDTP-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 181 Query: 405 VCEKE 409 C+ Sbjct: 182 KCQPV 186 Score = 39.9 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 8/70 (11%) Query: 906 HCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE----GSPQS--QCQSDH 959 H + C + + + + Y + VV + C DG+ + G+ CQS+ Sbjct: 117 HGDPMPCPKEDTPNSVWE--PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 174 Query: 960 QWNPPLAVCR 969 +W+ C+ Sbjct: 175 KWSNSKLKCQ 184 Score = 36.8 bits (83), Expect = 0.051, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 20/69 (28%), Gaps = 9/69 (13%) Query: 852 PPPPKTPNGNHTG---GNIARFSPGMSILYSCDQGYLLVGEA------LLLCTHEGTWSQ 902 P P A++ + +C G+ +V C G WS Sbjct: 119 DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSN 178 Query: 903 PAPHCKEVN 911 C+ V+ Sbjct: 179 SKLKCQPVD 187 Score = 34.1 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 22/64 (34%), Gaps = 7/64 (10%) Query: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLK----GSSQI--RCKADNTWDPEIP 655 C N +A Y + D V C GF + G++ C+++ W Sbjct: 123 CPKEDTPNSVWE-PAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 181 Query: 656 VCEK 659 C+ Sbjct: 182 KCQP 185 Score = 33.3 bits (74), Expect = 0.50, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 20/64 (31%), Gaps = 7/64 (10%) Query: 788 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV------IRCHTDNTWVPGVP 841 CP E + Y D+V + C GF + RV C ++ W Sbjct: 123 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 181 Query: 842 TCIK 845 C Sbjct: 182 KCQP 185 Score = 33.0 bits (73), Expect = 0.68, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 21/53 (39%), Gaps = 6/53 (11%) Query: 423 DRHMVRFDPGTSIKYSCNPGYVLV----GEESI--QCTSEGVWTPPVPQCKVA 469 + ++ ++ +C G+ +V G S C S G W+ +C+ Sbjct: 134 EPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPV 186 Score = 32.6 bits (72), Expect = 0.89, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 21/68 (30%), Gaps = 10/68 (14%) Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFS----MNGNKSVW--CQANNMWGPTRLP 144 CP+ P Y D V C F G S + CQ+N W Sbjct: 123 CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS----N 178 Query: 145 TCVSVFPL 152 + + P+ Sbjct: 179 SKLKCQPV 186 Score = 31.8 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 17/44 (38%), Gaps = 6/44 (13%) Query: 488 RPDVNSSCGEGYKLS------GSVYQECQGTIPWFMEIRLCKEI 525 R V +C +G+++ S Y CQ W C+ + Sbjct: 143 RDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPV 186 Score = 31.0 bits (68), Expect = 3.0, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 20/71 (28%), Gaps = 6/71 (8%) Query: 524 EITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 583 + CP + + + + V TC G E C SN Sbjct: 120 PMPCPKEDTPNS--VWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSN---- 173 Query: 584 GTWSGPAPLCK 594 G WS C+ Sbjct: 174 GKWSNSKLKCQ 184 >2WCY-A nrPDB Length = 155 Score = 53.4 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 670 QELPAGSRVELVNTS---CQDGYQLTGHAYQMCQDAENGIWFKKIPLCK--VIHCHPPPV 724 Q +P R E + S C+ Y+ G + +C E + +CK V+HC Sbjct: 9 QAVPKCQRWEKLQNSRCVCKMPYEC-GPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNY 67 Query: 725 IVNGKHTGMM 734 + G+ + + Sbjct: 68 TLTGRDSCTL 77 >4F4O-C nrPDB Length = 347 Score = 41.4 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 38/115 (33%), Gaps = 26/115 (22%) Query: 407 EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV--GEESIQCTSEGVWTPPVP 464 + C PP I G E ++Y C Y L G+ S WT V Sbjct: 30 DDSCPKPPEIPKGYVEH----------MVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKVT 79 Query: 465 QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEI 519 K+ CEA KP++ D G + +G+ PW ++ Sbjct: 80 GEKLPECEAVCG----KPKNP---VDQVQRIMGG-------SLDAKGSFPWQAKM 120 Score = 34.5 bits (77), Expect = 0.28, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 23/75 (30%), Gaps = 16/75 (21%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK--GSKQIRCNAQGTWEPS-----A 403 CP P + V V + C + L+ G ++ W Sbjct: 33 CPKPPEIPKGYVE---------HMVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKVTGEKL 83 Query: 404 PVCEKECQAPPNILN 418 P CE C P N ++ Sbjct: 84 PECEAVCGKPKNPVD 98 Score = 33.0 bits (73), Expect = 0.67, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 28/81 (34%), Gaps = 10/81 (12%) Query: 652 PEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK-- 709 E ++C E+P G +V CQ Y+L + N W Sbjct: 23 NEATDATDDSCPKPP----EIPKGYVEHMVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKV 78 Query: 710 ---KIPLCKVIHCHPPPVIVN 727 K+P C+ + C P V+ Sbjct: 79 TGEKLPECEAV-CGKPKNPVD 98 >1MD7-A nrPDB Length = 328 Score = 41.1 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 23/83 (27%), Gaps = 15/83 (18%) Query: 911 NCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLE----GS-----PQSQCQSDHQ 960 +C P + +G + + Y A + C + Y GS C + Sbjct: 1 DCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGI 60 Query: 961 WNPP-----LAVCRSRSLAPVLC 978 W + C PV Sbjct: 61 WKNEQKGEKIPRCLPVCGKPVNP 83 Score = 39.5 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 32/98 (32%), Gaps = 17/98 (17%) Query: 409 ECQAPPNILNGQ-KEDRHMVRFDPGTSIKYSCNPGYVLVGEES---------IQCTSEGV 458 +C P N+ NG + M I+Y C+ Y + + CT++G+ Sbjct: 1 DCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGI 60 Query: 459 WTPP-----VPQCKVAACEATGRQLLTKPQHQFVRPDV 491 W +P+C C + + Q Sbjct: 61 WKNEQKGEKIPRCLPV-CGKPVNP-VEQRQRIIGGQKA 96 >3OJY-B nrPDB Length = 537 Score = 36.4 bits (82), Expect = 0.069, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 16/54 (29%), Gaps = 6/54 (11%) Query: 243 DEGYRLQGPPSSRCVIAGQGVAWTKMPVC------EEIFCPSPPPILNGRHIGN 290 +G + I G+ W+ C + C +PPP G Sbjct: 475 SQGLACEVSYRKNTPIDGKWNCWSNWSSCSGRRKTRQRQCNNPPPQNGGSPCSG 528 >3NFP-I nrPDB Length = 223 Score = 36.0 bits (81), Expect = 0.090, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 54/185 (29%), Gaps = 32/185 (17%) Query: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYV--LVGEESIQCTSEGVWTPPVPQCKVA- 469 PP I + + + GT + C G+ G + CT + QC+ Sbjct: 7 PPEIPHATFKAMA---YKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTS 63 Query: 470 -ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCP 528 A T +Q+ +P+ Q + + P + C Sbjct: 64 SATRNTTKQVTPQPEEQ------------------KERKTTEMQSPMQPVDQASLPGHCR 105 Query: 529 PPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG 588 PP N A + F G V Y C G G + C + W+ Sbjct: 106 EPPPWENEA--TERIYHFVVGQMVYYQCVQGYRALH----RGPAESVCKMTHGKT-RWTQ 158 Query: 589 PAPLC 593 P +C Sbjct: 159 PQLIC 163 Score = 33.3 bits (74), Expect = 0.55, Method: Composition-based stats. Identities = 23/165 (13%), Positives = 38/165 (23%), Gaps = 31/165 (18%) Query: 108 YRHGDSVTFACKTNFSMNGNKSVWCQANN---MWGPTRLPTCVSVFPLECPALPMIHNGH 164 Y+ G + CK F + S++ C S Sbjct: 20 YKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEE 79 Query: 165 HTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNG 224 + + V C+ + N Sbjct: 80 QKERKTTEMQSPMQ--------------------------PVDQASLPGHCREPPPWENE 113 Query: 225 KVKEPPILRVGVTANFFCDEGYRL--QGPPSSRCVIAGQGVAWTK 267 + VG + C +GYR +GP S C + WT+ Sbjct: 114 ATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQ 158 Score = 31.8 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 44/195 (22%), Positives = 55/195 (28%), Gaps = 43/195 (22%) Query: 720 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGF--YLLGEKKLQCRSDSKGHGSWSGPSP 777 PP I H A + G ++ EC +GF G + C +S H SW Sbjct: 5 DDPPEIP---HATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSS-HSSWDN--- 57 Query: 778 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 837 QC + TR + T Sbjct: 58 QCQCTSSATR---------------------------NTTKQVTPQPEEQKERKTTEMQS 90 Query: 838 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY--LLVGEALLLC- 894 P P C PP N I F G + Y C QGY L G A +C Sbjct: 91 PMQPVDQASLPGHCREPPPWEN--EATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCK 148 Query: 895 THEG--TWSQPAPHC 907 G W+QP C Sbjct: 149 MTHGKTRWTQPQLIC 163 >2RJQ-A nrPDB Length = 378 Score = 35.7 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 13/54 (24%), Gaps = 10/54 (18%) Query: 253 SSRCVIAGQGVAWTKMPVCEEI----------FCPSPPPILNGRHIGNSLANVS 296 G +W C C +P P NGR+ A Sbjct: 300 YYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYR 353 >1CK7-A nrPDB Length = 631 Score = 35.7 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 37/228 (16%), Positives = 57/228 (25%), Gaps = 39/228 (17%) Query: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTG-TWSGPAPRCELSTSAVQCPHPQILRG 359 V Y F+ G+ CT + G W E CPH + Sbjct: 194 VKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTM 253 Query: 360 RMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQG-----TWEPSAPVCEKEC--QA 412 + + C F F +G+ C +G W + +++ Sbjct: 254 GGNAEGQP-----------CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGF 302 Query: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA-- 470 P G S C + +G + CTS G + C A Sbjct: 303 CPETAMSTVG---------GNSEGAPCVFPFTFLGNKYESCTSAGRSDGKM-WCATTANY 352 Query: 471 --------CEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510 C G L H F + L +Y + Sbjct: 353 DDDRKWGFCPDQGYSLFLVAAHAFGHAMGLEHSQDPGALMAPIYTYTK 400 >4WJG-C nrPDB Length = 315 Score = 35.3 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 23/75 (30%), Gaps = 16/75 (21%) Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK--GSKQIRCNAQGTWEPSA----- 403 CP P + V V + C + L+ G N + W A Sbjct: 1 CPKPPEIAHGYVEHS---------VRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKL 51 Query: 404 PVCEKECQAPPNILN 418 P CE C P N N Sbjct: 52 PECEAVCGKPKNPAN 66 Score = 34.5 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 26/78 (33%), Gaps = 18/78 (23%) Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV--GEESIQCTSEGVWTP-----P 462 C PP I +G E S++Y C Y L G+ +E W Sbjct: 1 CPKPPEIAHGYVEH----------SVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDK 50 Query: 463 VPQCKVAACEATGRQLLT 480 +P+C+ A C Sbjct: 51 LPECE-AVCGKPKNPANP 67 >5VAI-R nrPDB Length = 461 Score = 35.3 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 42/123 (34%), Gaps = 17/123 (13%) Query: 398 TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFD------PGTSIKYSCNPGY-----VLV 446 W C+ P + G +R + PG+ + SC VL Sbjct: 77 KWREYRRQCQHFLTEAPPLATGLFCNRTFDDYACWPDGAPGSFVNVSCPWYLPWASNVLQ 136 Query: 447 GEESIQCTSEGVWTPPVPQCKV----AACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLS 502 G CT+EG W P + CE + R + P+ + + + + GY LS Sbjct: 137 GHVYRFCTAEGHWLPKDNSSLPWRDLSECEESRRGEKSSPEERLLSLYIIYTV--GYALS 194 Query: 503 GSV 505 S Sbjct: 195 FSA 197 >1EAK-A nrPDB Length = 421 Score = 35.3 bits (79), Expect = 0.16, Method: Composition-based stats. Identities = 38/228 (16%), Positives = 58/228 (25%), Gaps = 39/228 (17%) Query: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTG-TWSGPAPRCELSTSAVQCPHPQILRG 359 V Y F+ G+ CT + G W E CPH + Sbjct: 192 VKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTM 251 Query: 360 RMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQG-----TWEPSAPVCEKEC--QA 412 + + C F F +G+ C +G W + +++ Sbjct: 252 GGNAEGQP-----------CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGF 300 Query: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA-- 470 P G S C + +G + CTS G + C A Sbjct: 301 CPETAMSTVG---------GNSEGAPCVFPFTFLGNKYESCTSAGRSDGKM-WCATTANY 350 Query: 471 --------CEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510 C G L HQF + L +Y + Sbjct: 351 DDDRKWGFCPDQGYSLFLVAAHQFGHAMGLEHSQDPGALMAPIYTYTK 398 >1L6J-A nrPDB Length = 425 Score = 34.1 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 27/162 (16%), Positives = 46/162 (28%), Gaps = 27/162 (16%) Query: 50 SCSGTFRLIGEKSLLCITKDKVDGT-WDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPY 108 +C F G C T + DG W + +++ CP + Sbjct: 210 ACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERL----------YT 259 Query: 109 RHGDSVTFACKTNFSMNGNKSVWCQANNM-----WGPTRLPTCVSVFPLECPALPMIHNG 163 R G++ C+ F G C + W T CP Sbjct: 260 RDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCP-------- 311 Query: 164 HHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 205 + ++ G S C + +G++ C S G+ Sbjct: 312 ---TRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDG 350 Score = 33.7 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 56/325 (17%), Positives = 91/325 (28%), Gaps = 68/325 (20%) Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW----CQANNMWGPTRLPTC 146 C P + G + H + +T+ N+S + ++V +A +W T Sbjct: 80 CGVPDLGRFQTFEGDLKWHHHN-ITYW-IQNYSEDLPRAVIDDAFARAFALWSAVTPLTF 137 Query: 147 VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAV 206 V+ + G G + + G L G Sbjct: 138 TRVYSRD----------ADIVIQFGVAEHGDGYPFDGKDGLLAHAFPP------GPGIQG 181 Query: 207 PPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ--GVA 264 ++ SLG+ V P A C + +G S C G+ G+ Sbjct: 182 DAHFDDDELWSLGK----GVVVPTRFGNADGAA--CHFPFIFEGRSYSACTTDGRSDGLP 235 Query: 265 WTKMPVC-----EEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIG 319 W FCPS + N G + FI G Sbjct: 236 WCSTTANYDTDDRFGFCPS-------ERLYTRDGNAD-GKPCQFP----------FIFQG 277 Query: 320 ESTLRCTVDSQKTG-TWSGPAPRCELSTSAVQCP--HPQILRGRMVSGQKDRYTYNDTVI 376 +S CT D + G W + CP + G +G+ Sbjct: 278 QSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGEL---------- 327 Query: 377 FACMFGFTLKGSKQIRCNAQGTWEP 401 C+F FT G + C ++G + Sbjct: 328 --CVFPFTFLGKEYSTCTSEGRGDG 350 Score = 33.3 bits (74), Expect = 0.61, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 47/169 (27%), Gaps = 13/169 (7%) Query: 439 CNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSS---C 495 C+ ++ G CT++G + +P C A T + P + D N+ C Sbjct: 211 CHFPFIFEGRSYSACTTDGR-SDGLPWCSTTANYDTDDRFGFCPSERLYTRDGNADGKPC 269 Query: 496 GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYT 555 + G Y C R C T G + G + Sbjct: 270 QFPFIFQGQSYSACTTDGRSDG-YRWC-ATTANYDRDKLFGFCPTRADSTVMGGNSA--- 324 Query: 556 CNPGPERGVEFSLIGESTIRCTSNDQERGT-WSGPAPLCKLSLLAVQCS 603 G F+ +G+ CTS + G W C Sbjct: 325 ---GELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCP 370 >3U9U-E nrPDB Length = 625 Score = 33.7 bits (75), Expect = 0.45, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 33/132 (25%), Gaps = 17/132 (12%) Query: 453 CTSEGVWTPPVPQCKVAACEATGRQLLTKPQ------HQFVRPDVNSSCGEGYKLSGSVY 506 C+S+G W P QC + GR + +F + C + Sbjct: 482 CSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENDSICVECDPQCEKMEDGL 541 Query: 507 QECQGTIPWFMEI-------RLCKEITCPPPPVIYNGA---HTGSSLEDFPYGTTVTYTC 556 C G P C E CP N + E P T C Sbjct: 542 LTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADPDRECHPCHPNCTQGC 600 Query: 557 NPGPERGVEFSL 568 N + Sbjct: 601 NGPTSHDCIYYP 612 Score = 31.8 bits (70), Expect = 1.8, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 30/136 (22%), Gaps = 20/136 (14%) Query: 197 CLSSGKWSAVPPTC-------EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249 C S G W P C C +G+ +E + CD Sbjct: 482 CSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFRE----FENDSICVECDPQCEKM 537 Query: 250 GPPSSRCVIAGQGVA-----WTKMPVCEEIFCPSPPPILNGRHIGNSLAN---VSYGSIV 301 C G + P C E CP N + + Sbjct: 538 EDGLLTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADPDRECHPCHPNC 596 Query: 302 TYTCDPDPEEGVNFIL 317 T C+ + Sbjct: 597 TQGCNGPTSHDCIYYP 612 >4ZXB-E nrPDB Length = 894 Score = 33.0 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 45/181 (24%), Gaps = 36/181 (19%) Query: 678 VELVNTSCQDGYQLTGHAY-----QMCQDAENGIWFKKIPLCK---------VIHCHPPP 723 + S +D + + +C G + HC Sbjct: 133 WSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVC 192 Query: 724 VIVNGKHTGMMAENFLYGNEVSYECDQG-----------FYLLGEKKLQCRSDSKGHGSW 772 + H AE +E C Q FYL G C W Sbjct: 193 PTICKSHGC-TAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDW 251 Query: 773 SGPSPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 831 R + C + K + H HN+ +C G+ MN S + C Sbjct: 252 --------RCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMN-SSNLLCT 302 Query: 832 T 832 Sbjct: 303 P 303 >5KQV-E nrPDB Length = 609 Score = 33.0 bits (73), Expect = 0.67, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 45/181 (24%), Gaps = 36/181 (19%) Query: 678 VELVNTSCQDGYQLTGHAY-----QMCQDAENGIWFKKIPLCK---------VIHCHPPP 723 + S +D + + +C G + HC Sbjct: 133 WSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVC 192 Query: 724 VIVNGKHTGMMAENFLYGNEVSYECDQG-----------FYLLGEKKLQCRSDSKGHGSW 772 + H AE +E C Q FYL G C W Sbjct: 193 PTICKSHGC-TAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDW 251 Query: 773 SGPSPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 831 R + C + K + H HN+ +C G+ MN S + C Sbjct: 252 --------RCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMN-SSNLLCT 302 Query: 832 T 832 Sbjct: 303 P 303 >5U8R-A nrPDB Length = 885 Score = 33.0 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 26/81 (32%), Gaps = 11/81 (13%) Query: 752 FYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDI 811 +Y G C ++ W R C N + + + H+ Sbjct: 224 YYYAGVCVPACPPNTYRFEGW--------RCVDRDFCAN---ILSAESSDSEGFVIHDGE 272 Query: 812 VYVDCNPGFIMNGSRVIRCHT 832 +C GFI NGS+ + C Sbjct: 273 CMQECPSGFIRNGSQSMYCIP 293 >4V2A-A nrPDB Length = 303 Score = 32.6 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 20/71 (28%), Gaps = 11/71 (15%) Query: 233 RVGVTANFFCDE----GYRLQGPPSSRCVIAGQGVAWTKMPVC-------EEIFCPSPPP 281 R+ TAN+ C R + + G W+K C C P P Sbjct: 212 RLADTANYTCVAKNIVARRRSASAAVIVYVDGSWSPWSKWSACGLDCTHWRSRECSDPAP 271 Query: 282 ILNGRHIGNSL 292 G + Sbjct: 272 RNGGEECQGTD 282 >1IGR-A nrPDB Length = 478 Score = 32.6 bits (72), Expect = 0.88, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 26/81 (32%), Gaps = 11/81 (13%) Query: 752 FYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDI 811 +Y G C ++ W R C N + + + H+ Sbjct: 224 YYYAGVCVPACPPNTYRFEGW--------RCVDRDFCAN---ILSAESSDSEGFVIHDGE 272 Query: 812 VYVDCNPGFIMNGSRVIRCHT 832 +C GFI NGS+ + C Sbjct: 273 CMQECPSGFIRNGSQSMYCIP 293 >2HR7-A nrPDB Length = 486 Score = 32.2 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 45/181 (24%), Gaps = 36/181 (19%) Query: 678 VELVNTSCQDGYQLTGHAY-----QMCQDAENGIWFKKIPLCK---------VIHCHPPP 723 + S +D + + +C G + HC Sbjct: 133 WSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVC 192 Query: 724 VIVNGKHTGMMAENFLYGNEVSYECDQG-----------FYLLGEKKLQCRSDSKGHGSW 772 + H AE +E C Q FYL G C W Sbjct: 193 PTICKSHGC-TAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDW 251 Query: 773 SGPSPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 831 R + C + K + H HN+ +C G+ MN S + C Sbjct: 252 --------RCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMN-SSNLLCT 302 Query: 832 T 832 Sbjct: 303 P 303 >2FON-A nrPDB Length = 683 Score = 32.2 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 20/146 (13%), Positives = 43/146 (29%), Gaps = 9/146 (6%) Query: 201 GKW--SAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258 G+W + P + + +A E R C Sbjct: 367 GEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECR------KLCGG 420 Query: 259 AGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILI 318 G + + +P ++ P+ + + +A +I P V+++ Sbjct: 421 HG-YLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTISQLGTGKKPVGTVSYMGR 479 Query: 319 GESTLRCTVDSQKTGTWSGPAPRCEL 344 E ++C D ++ W P+ E Sbjct: 480 IEHLMQCRSDVKQAEDWLKPSAVLEA 505 >3P11-A nrPDB Length = 522 Score = 31.8 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 45/164 (27%), Gaps = 25/164 (15%) Query: 823 NGSRVIRCHT---DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYS 879 NG CH W PG C C H G +P Sbjct: 160 NGRSCPPCHEVCKGRCWGPGSEDCQTLTKTIC----APQCNGHCFGP----NPNQCCHDE 211 Query: 880 CDQGYLLVGE-ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKM--YQYGAV 936 C G + C H P C P + + LEP YQYG V Sbjct: 212 CAGGCSGPQDTDCFACRHFNDSGACVP-----RCPQPLVYNKLTFQLEPNPHTKYQYGGV 266 Query: 937 VTLECEDGYMLEGSP-QSQCQSDHQWNPPLAVCRSRSLAPVLCG 979 C ++++ + C D + V ++ CG Sbjct: 267 CVASCPHNFVVDQTSCVRACPPD-----KMEVDKNGLKMCEPCG 305 >5FTT-A nrPDB Length = 285 Score = 31.0 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 13/43 (30%), Gaps = 10/43 (23%) Query: 258 IAGQGVAWTKMPVC----------EEIFCPSPPPILNGRHIGN 290 + G +WT+ C C +P P+ G Sbjct: 218 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG 260 >5O4O-C nrPDB Length = 649 Score = 30.7 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 45/164 (27%), Gaps = 25/164 (15%) Query: 823 NGSRVIRCHT---DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYS 879 NG CH W PG C C H G +P Sbjct: 179 NGRSCPPCHEVCKGRCWGPGSEDCQTLTKTIC----APQCNGHCFGP----NPNQCCHDE 230 Query: 880 CDQGYLLVGE-ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKM--YQYGAV 936 C G + C H P C P + + LEP YQYG V Sbjct: 231 CAGGCSGPQDTDCFACRHFNDSGACVP-----RCPQPLVYNKLTFQLEPNPHTKYQYGGV 285 Query: 937 VTLECEDGYMLEGSP-QSQCQSDHQWNPPLAVCRSRSLAPVLCG 979 C ++++ + C D + V ++ CG Sbjct: 286 CVASCPHNFVVDQTSCVRACPPD-----KMEVDKNGLKMCEPCG 324 >2JND-A nrPDB Length = 119 Score = 30.7 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 23/79 (29%), Gaps = 10/79 (12%) Query: 333 GTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR 392 G +SGP C + + PQ G +V Y + + Sbjct: 37 GNFSGPYTYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIK--------YNTTRNAYRE 88 Query: 393 CNAQGTW--EPSAPVCEKE 409 C GTW + CE Sbjct: 89 CLENGTWASRVNYSHCEPI 107 >1W0R-A nrPDB Length = 442 Score = 29.9 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 50/179 (27%), Gaps = 31/179 (17%) Query: 132 CQANNMWGPTRLPTCVSVFPLECPALPMIHN---GHHTSENVGSIAPGLSV-TYSCESGY 187 C WGP VS P+ C + H ++ G G + T+ C + Sbjct: 227 CPVAGGWGPWGP---VSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTA- 282 Query: 188 LLVGEKIINCLSSGKW--SAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEG 245 + C G+W C KS+ + P G T +G Sbjct: 283 -------VPCPVDGEWDSWGEWSPCIRRNMKSIS-----CQEIPGQQSRGRTCRGRKFDG 330 Query: 246 YRLQGPPS--------SRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVS 296 +R G C + G W+ +C P+P R L Sbjct: 331 HRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ-RLCTPLLPKYP 388 >3M0C-C nrPDB Length = 791 Score = 29.1 bits (63), Expect = 9.5, Method: Composition-based stats. Identities = 34/258 (13%), Positives = 61/258 (23%), Gaps = 17/258 (6%) Query: 714 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773 C+ C + +G + +S C G + G + +C Sbjct: 31 CQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRC---- 86 Query: 774 GPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYV--DCNPGFIMNGSRVIRCH 831 C CP S + DC G V+ C Sbjct: 87 DGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCG 146 Query: 832 T------DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 885 +T +P + C SP + + C G Sbjct: 147 PASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGEC 206 Query: 886 LVGEALLLCTHEGTWSQPAPHCKEVNCSSP----ADMDGIQKGLEPRKMYQYGA-VVTLE 940 + + +C C +D + I + + Y + Sbjct: 207 IHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVG 266 Query: 941 CEDGYMLEGSPQSQCQSD 958 C + + EG + +C S Sbjct: 267 CVNVTLCEGPNKFKCHSG 284 >3LTF-A nrPDB Length = 601 Score = 29.1 bits (63), Expect = 9.5, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 44/141 (31%), Gaps = 15/141 (10%) Query: 50 SCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK----CEYFNKYSSCPEPI------VPGG 99 C+G R G K C G P K C+ F C E P Sbjct: 195 QCAGG-RCYGPKPRECCHLFCAGGC-TGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTT 252 Query: 100 YKIRGSTP--YRHGDSVTFACKTNFSM-NGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156 Y + + Y +G + C + NG C + M C P CP Sbjct: 253 YVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPG 312 Query: 157 LPMIHNGHHTSENVGSIAPGL 177 + ++H G+ S ++ G Sbjct: 313 VTVLHAGNIDSFRNCTVIDGN 333 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.114 0.328 Lambda K H 0.267 0.0350 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,347,521 Number of Sequences: 36641 Number of extensions: 1545378 Number of successful extensions: 4728 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 3245 Number of HSP's gapped (non-prelim): 538 length of query: 1033 length of database: 10,336,785 effective HSP length: 107 effective length of query: 926 effective length of database: 6,416,198 effective search space: 5941399348 effective search space used: 5941399348 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 64 (29.5 bits)