BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P19971 (482 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1UOU-A nrPDB 885 0.0 1BRW-A nrPDB 297 7e-81 5EY3-A nrPDB 281 4e-76 2DSJ-A nrPDB 277 8e-75 5EP8-A nrPDB 272 2e-73 3H5Q-A nrPDB 269 2e-72 4GA6-A nrPDB 162 4e-40 4GA4-A nrPDB 159 2e-39 4GTN-A nrPDB 49 6e-06 1KGZ-A nrPDB 41 0.001 1VQU-A nrPDB 40 0.003 1ZYK-A nrPDB 35 0.049 1DJ2-A nrPDB 31 1.2 4QS9-A nrPDB 31 1.3 1C5K-A nrPDB 30 2.0 2B8N-A nrPDB 30 2.1 4MUO-A nrPDB 30 2.9 3C3W-A nrPDB 28 6.9 >1UOU-A nrPDB Length = 474 Score = 885 bits (2288), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/473 (99%), Positives = 469/473 (99%), Gaps = 2/473 (0%) Query: 10 GAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA 69 G PPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA Sbjct: 4 GIPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA 63 Query: 70 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL 129 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL Sbjct: 64 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL 123 Query: 130 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE 189 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE Sbjct: 124 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE 183 Query: 190 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR 249 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR Sbjct: 184 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR 243 Query: 250 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL 309 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL Sbjct: 244 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL 303 Query: 310 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR 369 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR Sbjct: 304 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR 363 Query: 370 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQ 429 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAG RAGEPLRLGVGAELLVDVGQ Sbjct: 364 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAG--RAGEPLRLGVGAELLVDVGQ 421 Query: 430 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ 482 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAP PFAELVLPPQQ Sbjct: 422 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPLPFAELVLPPQQ 474 >1BRW-A nrPDB Length = 433 Score = 297 bits (761), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 178/444 (40%), Positives = 261/444 (58%), Gaps = 12/444 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ +LI KRDG L++ +I V NG Q+ A+ MAI RGM EET+ LT A Sbjct: 2 RMVDLIAKKRDGKALTKEEIEWIVRGYTNGDIPDYQMSALAMAIYFRGMTEEETAALTMA 61 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + QSG+ L+ + R VDKHSTGGVGD +LVL P +A+ G V +SGRGLGHTGGT Sbjct: 62 MVQSGEMLDLS-SIRGVKVDKHSTGGVGDTTTLVLGPLVASVGVPVAKMSGRGLGHTGGT 120 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLES+PGF+V S ++ L+++ G I+GQ+ L PAD LYA RDVTATV+S+PLI Sbjct: 121 IDKLESVPGFHVEISKDEFIRLVNENGIAIIGQTGDLTPADKKLYALRDVTATVNSIPLI 180 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A ++AR LA+ +V +G +G R A ++ M Sbjct: 181 ASSIMSKKIAAGADAIVLDVKTGAGAFMKKLDEARRLARVMVDIGKRVGRRTMAVISDMS 240 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLG VG+ALEV+EA+ + G GP DL +L TLG +++L+ A + + + A+ Sbjct: 241 QPLGYAVGNALEVKEAIETLKGNGPHDLTELCLTLGSHMVYLAEKAPSLDEARRLLEEAI 300 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 G+A+ F+ LAAQG D + L LP+A + A ADG V + A Sbjct: 301 RSGAAIAAFKTFLAAQGGDASVVDDLDK---------LPKAAYTSTVTAAADGYVAEMAA 351 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRA 454 + LGAGR++ + + L VG L +G R+++G +H + P + + + Sbjct: 352 DDIGTAAMWLGAGRAKKEDVIDLAVGIVLHKKIGDRVQKGEALATIHSNRPDVLDVKEK- 410 Query: 455 LQEALVLSDRAPFAAPSPFAELVL 478 ++ A+ LS + P A P E ++ Sbjct: 411 IEAAIRLSPQ-PVARPPLIYETIV 433 >5EY3-A nrPDB Length = 442 Score = 281 bits (719), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 174/438 (39%), Positives = 243/438 (55%), Gaps = 10/438 (2%) Query: 38 ELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQ 97 E+IR KRDG LS+ +IR F+ + + + QI A+ M I M + E LT A+ Sbjct: 8 EIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRD 67 Query: 98 SGQQLEWPE-AWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLD 156 SG L+W +VDKHSTGGVGD SL+L P +AACG VPMISGRGLGHTGGTLD Sbjct: 68 SGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLD 127 Query: 157 KLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITA 216 KLE+IPGF++ + + ++ G I+GQ+ L PAD YA RD+TATVDS+PLIT Sbjct: 128 KLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITG 187 Query: 217 SILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKP 276 SIL+KKL EGL ALV+DVK G A P E + LA+ +VGV G+R A LT M++ Sbjct: 188 SILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQV 247 Query: 277 LGRCVGHALEVEEALLCMDGAG-PPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALD 335 L G+A+EV EA+ + G P L D+ L +L A A+ A++ A LD Sbjct: 248 LASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLD 307 Query: 336 DGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRAL 395 +G A F RM+AAQ P S + LP A + + A +G + + Sbjct: 308 NGKAAEVFGRMVAAQK-GP-------SDFVENYDKYLPTAMLSKAVYADTEGFISAMDTR 359 Query: 396 PLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRAL 455 L + + +G GR +A + + VG + +G + P +H A ++A+ Sbjct: 360 ALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAV 419 Query: 456 QEALVLSDRAPFAAPSPF 473 + A++L D+AP + PS + Sbjct: 420 KAAIILDDKAPASTPSVY 437 >2DSJ-A nrPDB Length = 423 Score = 277 bits (708), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 186/421 (44%), Positives = 240/421 (57%), Gaps = 26/421 (6%) Query: 39 LIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQS 98 IR KR+G + D+ F+ + Q+ A LMA LRG+D EET LT+ +A+S Sbjct: 6 FIREKREGKKHRREDLEAFLLGYLRDEVPDYQVSAWLMAAFLRGLDPEETLWLTETMARS 65 Query: 99 GQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKL 158 G+ L+ + VDKHS+GGVGDKVSLV+ P LAA GC +SGRGL HTGGT+DKL Sbjct: 66 GKVLDL--SGLPHPVDKHSSGGVGDKVSLVVGPILAASGCTFAKMSGRGLAHTGGTIDKL 123 Query: 159 ESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASI 218 ES+PG+ + + + G I QS L P DG LYA RDVTATV+S+PLI +SI Sbjct: 124 ESVPGWRGEMTEAEFLERARRVGLVIAAQSPDLAPLDGKLYALRDVTATVESVPLIASSI 183 Query: 219 LSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLG 278 +SKKL G ++V+DVK G A E+AR LAKT+V +G G RV A LT+M+ PLG Sbjct: 184 MSKKLAAGARSIVLDVKVGRGAFMKTLEEARLLAKTMVAIGQGAGRRVRALLTSMEAPLG 243 Query: 279 RCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGS 338 R VG+A+EV EA+ + G GP DL ++ L L L G A+ AL+ G+ Sbjct: 244 RAVGNAIEVREAIEALKGEGPGDLLEVALALAEEALRLEGLDPALAR------KALEGGA 297 Query: 339 ALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLA 398 AL +F L AQG DP RA+ E LLP A E+ L A +G V V A + Sbjct: 298 ALEKFRAFLEAQGGDP---RAV------EDFSLLPLA-EEHPLRAEREGVVREVDAYKVG 347 Query: 399 LVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEA 458 L + LG GR R GEP+ GVG LL G R+ RG + AL + R L+EA Sbjct: 348 LAVLALGGGRKRKGEPIDHGVGVYLLKKPGDRVERG--------EALALVYHRRRGLEEA 399 Query: 459 L 459 L Sbjct: 400 L 400 >5EP8-A nrPDB Length = 433 Score = 272 bits (695), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 160/407 (39%), Positives = 239/407 (58%), Gaps = 10/407 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ ++I K++G L+ +I+ FV +GS Q A+ MAI R M E + LT A Sbjct: 2 RMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAIFFRDMSDRERADLTMA 61 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + SG+ ++ A VDKHSTGGVGD +LVLAP +AA V +SGRGLGHTGGT Sbjct: 62 MVNSGETIDLS-AIEGIKVDKHSTGGVGDTTTLVLAPLVAALDVPVAKMSGRGLGHTGGT 120 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLE+I GF+V + + L+++ ++GQS L PAD LYA RDVT TV+S+PLI Sbjct: 121 IDKLEAIDGFHVELTKREFIKLVNRDKVAVIGQSGNLTPADKKLYALRDVTGTVNSIPLI 180 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A +E A ELAK +V +G ++G + A ++ M Sbjct: 181 ASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMVRIGNNVGRQTMAVISDMS 240 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLG +G+ALEV+EA+ + G GP DL +LV TLG ++ L+ A T + A++ + Sbjct: 241 QPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVVLAKKADTLDEARAKLEEVM 300 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 +G AL +F+ L QG D + P++ LP+A Q ++ A G V + A Sbjct: 301 KNGKALEKFKDFLKNQGGDSSIV-----DDPSK----LPQAAYQIDVPAKEAGVVSEIVA 351 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVH 441 + + LGAGR+ + + L VG L VG ++ +G P + ++ Sbjct: 352 DEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLY 398 >3H5Q-A nrPDB Length = 436 Score = 269 bits (688), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 156/409 (38%), Positives = 232/409 (56%), Gaps = 10/409 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ ++I KRDG L+ +I F+ V G Q ++ MAI + M+ +E LT A Sbjct: 5 RMIDIIEKKRDGHTLTTEEINFFIGGYVKGDIPDYQASSLAMAIYFQDMNDDERVALTMA 64 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + SG ++ + + VDKHSTGGVGD +LVLAP +AA V +SGRGLGHTGGT Sbjct: 65 MVNSGDMIDLSD-IKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGT 123 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLE+I GF+V L+++ +VGQS L PAD LYA RDVT TV+S+PLI Sbjct: 124 IDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLI 183 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A E A LA +V +G ++G A ++ M+ Sbjct: 184 ASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMN 243 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLGR +G+ALE++EA+ + G GP DL +LV TLG ++ L+ A T + A + A+ Sbjct: 244 QPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAI 303 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 + G+AL +F+ + QG D + + + LP+A+ Q E A G V + + Sbjct: 304 NSGAALEKFKTFIKNQGGDE---------TVIDHPERLPQAQYQIEYKAKKSGYVTELVS 354 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRD 443 + + LGAGR + + L VG L +G ++ G L +H + Sbjct: 355 NDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSN 403 >4GA6-A nrPDB Length = 513 Score = 162 bits (409), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 139/454 (30%), Positives = 225/454 (49%), Gaps = 43/454 (9%) Query: 17 DFS-GEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAML 75 +FS GE +P +PE + I+ K G +L + +I V +V+ + +I + + Sbjct: 70 NFSEGETVSVIPAGTPESVRY---IKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFV 126 Query: 76 MAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGV-GDKVSLVLAPALA 134 A+ + G+D++E + LT A+A++G L+ R+ ++D HS GGV G+K ++++ P +A Sbjct: 127 TALEINGLDMDEIAALTIAMAETGDMLDID---RKPIMDVHSIGGVPGNKTNILVVPIVA 183 Query: 135 ACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIV-GQSEQLVP 193 A G +P S R + GT D +E +V S ++++ ++++ G C+V G + L P Sbjct: 184 AAGLTIPKTSSRAITSAAGTADVVEVFA--DVSFSLDEIKRIVEKVGACLVWGGALNLAP 241 Query: 194 ADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAK 253 AD I A + ++D L+ ASI+SKK G +++D+ G E+AR LA+ Sbjct: 242 ADDITIKA-ERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLAR 300 Query: 254 TLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLC-MDGAGPPDLRDLVTTLGGA 312 + +G LG V A+T +P+G VG ALE EAL M G GP L + T L G Sbjct: 301 DFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGI 360 Query: 313 LLWLSGH--AGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQ 370 LL + G AGT + A + L+ G A + + ++ AQG DP + P E Sbjct: 361 LLEMGGVAPAGTGKKMAKEI---LESGKAWEKMKEIIEAQGGDPNI-------KPEE--- 407 Query: 371 LLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQR 430 +P + A G V A+ + A AG P G G EL V VG++ Sbjct: 408 -IPIGDKTYTFTAATSGYV-------TAIDNRAITAIARAAGAPEDKGAGIELYVKVGEK 459 Query: 431 LRRGTPWLRVHRDGPALSGPQSRALQEALVLSDR 464 ++ G P +H + A L +A+VL+ R Sbjct: 460 VKEGDPLFTIHAEHEA-------RLDQAIVLARR 486 >4GA4-A nrPDB Length = 440 Score = 159 bits (403), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 134/437 (30%), Positives = 217/437 (49%), Gaps = 42/437 (9%) Query: 36 LPE---LIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLT 92 +PE I+ K G +L + +I V +V+ + +I + + A+ + G+D++E + LT Sbjct: 1 MPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALT 60 Query: 93 QALAQSGQQLEWPEAWRQQLVDKHSTGGV-GDKVSLVLAPALAACGCKVPMISGRGLGHT 151 A+A++G L+ R+ ++D HS GGV G+K ++++ P +AA G +P S R + Sbjct: 61 IAMAETGDMLDID---RKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSA 117 Query: 152 GGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIV-GQSEQLVPADGILYAARDVTATVDS 210 GT D +E +V S ++++ ++++ G C+V G + L PAD I A + ++D Sbjct: 118 AGTADVVEVFA--DVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKA-ERALSIDP 174 Query: 211 LPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAAL 270 L+ ASI+SKK G +++D+ G E+AR LA+ + +G LG V A+ Sbjct: 175 TGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAI 234 Query: 271 TAMDKPLGRCVGHALEVEEALLC-MDGAGPPDLRDLVTTLGGALLWLSGH--AGTQAQGA 327 T +P+G VG ALE EAL M G GP L + T L G LL + G AGT + A Sbjct: 235 TYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGILLEMGGVAPAGTGKKMA 294 Query: 328 ARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADG 387 + L+ G A + + ++ AQG DP + P E +P + A G Sbjct: 295 KEI---LESGKAWEKMKEIIEAQGGDPNI-------KPEE----IPIGDKTYTFTAATSG 340 Query: 388 TVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPAL 447 V A+ + A AG P G G EL V VG++++ G P +H + A Sbjct: 341 YV-------TAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEA- 392 Query: 448 SGPQSRALQEALVLSDR 464 L +A+VL+ R Sbjct: 393 ------RLDQAIVLARR 403 >4GTN-A nrPDB Length = 353 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 36/138 (26%), Positives = 69/138 (50%), Gaps = 6/138 (4%) Query: 48 RLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEA 107 L++A + + +++ G+A AQIGA++M +R++G ++E + + + + +++ + Sbjct: 19 HLTQAQMEDVMRSIMQGNATEAQIGALMMGLRMKGESIDEITAAARVMRELAIKIDVSDI 78 Query: 108 WRQQLVDKHSTGGVGD---KVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGF 164 Q LVD TGG G VS + +AA G + RG+ G+ D LE G Sbjct: 79 --QYLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQ-AGI 135 Query: 165 NVIQSPEQMQVLLDQAGC 182 N+ +Q + + + G Sbjct: 136 NLDLDMQQTERCIREMGV 153 >1KGZ-A nrPDB Length = 345 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 8/141 (5%) Query: 49 LSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAW 108 +++ + AA+V G + +Q+ A L+++++RG EE + AL Q P+ Sbjct: 26 MTQEESHQLFAAIVRGELEDSQLAAALISMKMRGERPEEIAGAASALLADAQPFPRPD-- 83 Query: 109 RQQLVDKHSTGGVG-DKVSLVLAPAL--AACGCKVPMISGRGLGH-TGGTLDKLESIPGF 164 D TGG G + +++ A A A+CG KV R + G+ D L++ G Sbjct: 84 -YDFADIVGTGGDGTNSINISTASAFVAASCGAKVAKHGNRSVCQPLAGSCDLLQAF-GI 141 Query: 165 NVIQSPEQMQVLLDQAGCCIV 185 + S E + LD C + Sbjct: 142 RLDMSAEDSRQALDDLNVCFL 162 >1VQU-A nrPDB Length = 374 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 13/125 (10%) Query: 72 GAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQ--------QLVDKHSTGGVGD 123 GA+L A+ +G+ +E + + + L QS ++ E + Q ++D TGG G Sbjct: 63 GAILTALNFKGVSADELTGMAEVL-QSQSKMGTGENYSQLPITNSPFSIIDTCGTGGDGS 121 Query: 124 ---KVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQA 180 +S +A AA G V R G+ D LE++ G N+ SPE++Q L + Sbjct: 122 STFNISTAVAFVAAAYGVPVAKHGNRSASSLTGSADVLEAL-GVNLGASPEKVQAALQEV 180 Query: 181 GCCIV 185 G + Sbjct: 181 GITFL 185 >1ZYK-A nrPDB Length = 345 Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 8/128 (6%) Query: 60 AVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTG 119 A++ G + A+L+A+R++G E +A+ + +++ P A +D TG Sbjct: 27 AIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNA-----IDTAGTG 81 Query: 120 GVG-DKVSLVLAPA-LAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLL 177 G G V++ A A L + V R + G+ D LE++ G+N+I PE+ + L+ Sbjct: 82 GDGLGTVNVSTASAILLSLVNPVAKHGNRAVSGKSGSADVLEAL-GYNIIVPPERAKELV 140 Query: 178 DQAGCCIV 185 ++ + Sbjct: 141 NKTNFVFL 148 >1DJ2-A nrPDB Length = 443 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 42/139 (30%), Positives = 57/139 (41%), Gaps = 22/139 (15%) Query: 199 YAARDVTATVDSLPLITASILSKK--LVEGLSALVVDVKFGGAAVFPNQEQARELAKTLV 256 YA R D++ I SI KK LVEG A ++D+ FG +P + A Sbjct: 211 YADRLEPYITDTVHFINDSISQKKKVLVEGGQATMLDIDFG---TYPFVTSSSPSAG--- 264 Query: 257 GVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWL 316 G GL +A ++ VG + V +A G+GP +L T GG LL L Sbjct: 265 --GICTGLGIAPSV----------VGDLIGVVKAYTTRVGSGPFPTENLGT--GGDLLRL 310 Query: 317 SGHAGTQAQGAARVAAALD 335 +G G R LD Sbjct: 311 AGQEFGTTTGRPRRCGWLD 329 >4QS9-A nrPDB Length = 474 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 5/96 (5%) Query: 247 QARELAKTLVGVGASLGLRVAAA-LTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDL 305 + R++ +L + A+ G R++AA + + K LGR EV+++++ MDG Sbjct: 368 KMRKVVISLCNIIATRGARLSAAGIYGILKKLGRDTTKDEEVQKSVIAMDGGLFEHYTQF 427 Query: 306 VTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALG 341 + +L L G +A G+ V + +DGS +G Sbjct: 428 SECMESSLKEL---LGDEASGSVEVTHS-NDGSGIG 459 >1C5K-A nrPDB Length = 439 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 8/90 (8%) Query: 226 GLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHAL 285 G+ A+VV V PN + + +A LV G + G +A ++K R GH Sbjct: 96 GIDAVVV------GQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTA 149 Query: 286 --EVEEALLCMDGAGPPDLRDLVTTLGGAL 313 EV E L + GA + +V T GG Sbjct: 150 SDEVFEKLTGIKGAFRTRIAYVVQTNGGQF 179 >2B8N-A nrPDB Length = 429 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 22/41 (53%) Query: 72 GAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQL 112 G+ L + L G+ LEE LT AL +SG +E R+ L Sbjct: 137 GSSLFELPLEGVSLEEIQKLTSALLKSGASIEEINTVRKHL 177 >4MUO-A nrPDB Length = 328 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 33/72 (45%) Query: 34 KQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQ 93 K + E+ R K L RG A ++NG ++G +L+A+R++G E + Sbjct: 5 KIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYE 64 Query: 94 ALAQSGQQLEWP 105 A+ +L P Sbjct: 65 AMQNHTIKLTPP 76 >3C3W-A nrPDB Length = 225 Score = 28.5 bits (62), Expect = 6.9, Method: Compositional matrix adjust. Identities = 39/113 (34%), Positives = 55/113 (48%), Gaps = 10/113 (8%) Query: 303 RDLVTTLGGA-LLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALC 361 R LV LG L + G AG+ A+ ARV AA D + L R+ G++ L R L Sbjct: 15 RGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDVAVLD--VRLPDGNGIE--LCRDLL 70 Query: 362 SGSPAERRQLLPRAREQEEL----LAPADG-TVELVRALPLALVLHELGAGRS 409 S P R +L E + LA A G V+ ++ + LA + ++GAGRS Sbjct: 71 SRMPDLRCLILTSYTSDEAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRS 123 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1UOU-A nrPDB 614 e-176 1BRW-A nrPDB 547 e-156 3H5Q-A nrPDB 539 e-153 5EP8-A nrPDB 515 e-146 5EY3-A nrPDB 507 e-144 2DSJ-A nrPDB 467 e-132 4GA6-A nrPDB 415 e-116 4GA4-A nrPDB 396 e-110 4GTN-A nrPDB 145 3e-35 1KGZ-A nrPDB 137 9e-33 Sequences not found previously or not previously below threshold: 1ZYK-A nrPDB 99 3e-21 4HKM-A nrPDB 82 7e-16 1VQU-A nrPDB 81 1e-15 5NOF-A nrPDB 79 3e-15 4IJ1-A nrPDB 70 2e-12 1V8G-A nrPDB 67 1e-11 4MUO-A nrPDB 46 4e-05 6HIZ-Ck nrPDB 37 0.014 1O7X-A nrPDB 32 0.44 2ISS-A nrPDB 29 3.3 1X7P-A nrPDB 29 6.1 >1UOU-A nrPDB Length = 474 Score = 614 bits (1584), Expect = e-176, Method: Composition-based stats. Identities = 469/473 (99%), Positives = 469/473 (99%), Gaps = 2/473 (0%) Query: 10 GAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA 69 G PPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA Sbjct: 4 GIPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGA 63 Query: 70 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL 129 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL Sbjct: 64 QIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVL 123 Query: 130 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE 189 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE Sbjct: 124 APALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE 183 Query: 190 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR 249 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR Sbjct: 184 QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQAR 243 Query: 250 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL 309 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL Sbjct: 244 ELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTL 303 Query: 310 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR 369 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR Sbjct: 304 GGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERR 363 Query: 370 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQ 429 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGR AGEPLRLGVGAELLVDVGQ Sbjct: 364 QLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGR--AGEPLRLGVGAELLVDVGQ 421 Query: 430 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ 482 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAP PFAELVLPPQQ Sbjct: 422 RLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPLPFAELVLPPQQ 474 >1BRW-A nrPDB Length = 433 Score = 547 bits (1410), Expect = e-156, Method: Composition-based stats. Identities = 178/444 (40%), Positives = 261/444 (58%), Gaps = 12/444 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ +LI KRDG L++ +I V NG Q+ A+ MAI RGM EET+ LT A Sbjct: 2 RMVDLIAKKRDGKALTKEEIEWIVRGYTNGDIPDYQMSALAMAIYFRGMTEEETAALTMA 61 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + QSG+ L+ + R VDKHSTGGVGD +LVL P +A+ G V +SGRGLGHTGGT Sbjct: 62 MVQSGEMLDLS-SIRGVKVDKHSTGGVGDTTTLVLGPLVASVGVPVAKMSGRGLGHTGGT 120 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLES+PGF+V S ++ L+++ G I+GQ+ L PAD LYA RDVTATV+S+PLI Sbjct: 121 IDKLESVPGFHVEISKDEFIRLVNENGIAIIGQTGDLTPADKKLYALRDVTATVNSIPLI 180 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A ++AR LA+ +V +G +G R A ++ M Sbjct: 181 ASSIMSKKIAAGADAIVLDVKTGAGAFMKKLDEARRLARVMVDIGKRVGRRTMAVISDMS 240 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLG VG+ALEV+EA+ + G GP DL +L TLG +++L+ A + + + A+ Sbjct: 241 QPLGYAVGNALEVKEAIETLKGNGPHDLTELCLTLGSHMVYLAEKAPSLDEARRLLEEAI 300 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 G+A+ F+ LAAQG D + L LP+A + A ADG V + A Sbjct: 301 RSGAAIAAFKTFLAAQGGDASVVDDLDK---------LPKAAYTSTVTAAADGYVAEMAA 351 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRA 454 + LGAGR++ + + L VG L +G R+++G +H + P + + + Sbjct: 352 DDIGTAAMWLGAGRAKKEDVIDLAVGIVLHKKIGDRVQKGEALATIHSNRPDVLDVKEK- 410 Query: 455 LQEALVLSDRAPFAAPSPFAELVL 478 ++ A+ LS + P A P E ++ Sbjct: 411 IEAAIRLSPQ-PVARPPLIYETIV 433 >3H5Q-A nrPDB Length = 436 Score = 539 bits (1388), Expect = e-153, Method: Composition-based stats. Identities = 159/443 (35%), Positives = 246/443 (55%), Gaps = 13/443 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ ++I KRDG L+ +I F+ V G Q ++ MAI + M+ +E LT A Sbjct: 5 RMIDIIEKKRDGHTLTTEEINFFIGGYVKGDIPDYQASSLAMAIYFQDMNDDERVALTMA 64 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + SG ++ + + VDKHSTGGVGD +LVLAP +AA V +SGRGLGHTGGT Sbjct: 65 MVNSGDMIDLSD-IKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGT 123 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLE+I GF+V L+++ +VGQS L PAD LYA RDVT TV+S+PLI Sbjct: 124 IDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLI 183 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A E A LA +V +G ++G A ++ M+ Sbjct: 184 ASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMN 243 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLGR +G+ALE++EA+ + G GP DL +LV TLG ++ L+ A T + A + A+ Sbjct: 244 QPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAI 303 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 + G+AL +F+ + QG D + + + LP+A+ Q E A G V + + Sbjct: 304 NSGAALEKFKTFIKNQGGDETVI---------DHPERLPQAQYQIEYKAKKSGYVTELVS 354 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRA 454 + + LGAGR + + L VG L +G ++ G L +H + + + Sbjct: 355 NDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSNRQDVDDVVKK- 413 Query: 455 LQEALVLSDRAPFAAPSPFAELV 477 L ++ ++D +P+ +++ Sbjct: 414 LDSSITIADH--VVSPTLIHKII 434 >5EP8-A nrPDB Length = 433 Score = 515 bits (1325), Expect = e-146, Method: Composition-based stats. Identities = 163/443 (36%), Positives = 249/443 (56%), Gaps = 13/443 (2%) Query: 35 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQA 94 ++ ++I K++G L+ +I+ FV +GS Q A+ MAI R M E + LT A Sbjct: 2 RMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAIFFRDMSDRERADLTMA 61 Query: 95 LAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + SG+ ++ A VDKHSTGGVGD +LVLAP +AA V +SGRGLGHTGGT Sbjct: 62 MVNSGETIDLS-AIEGIKVDKHSTGGVGDTTTLVLAPLVAALDVPVAKMSGRGLGHTGGT 120 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 +DKLE+I GF+V + + L+++ ++GQS L PAD LYA RDVT TV+S+PLI Sbjct: 121 IDKLEAIDGFHVELTKREFIKLVNRDKVAVIGQSGNLTPADKKLYALRDVTGTVNSIPLI 180 Query: 215 TASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMD 274 +SI+SKK+ G A+V+DVK G A +E A ELAK +V +G ++G + A ++ M Sbjct: 181 ASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMVRIGNNVGRQTMAVISDMS 240 Query: 275 KPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAAL 334 +PLG +G+ALEV+EA+ + G GP DL +LV TLG ++ L+ A T + A++ + Sbjct: 241 QPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVVLAKKADTLDEARAKLEEVM 300 Query: 335 DDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA 394 +G AL +F+ L QG D + + LP+A Q ++ A G V + A Sbjct: 301 KNGKALEKFKDFLKNQGGDSSIV---------DDPSKLPQAAYQIDVPAKEAGVVSEIVA 351 Query: 395 LPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRA 454 + + LGAGR+ + + L VG L VG ++ +G P + ++ + + ++ Sbjct: 352 DEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYANRENVDEVIAKV 411 Query: 455 LQEALVLSDRAPFAAPSPFAELV 477 + ++ A AP L+ Sbjct: 412 YDN-IRIA--AEAKAPKLIHTLI 431 >5EY3-A nrPDB Length = 442 Score = 507 bits (1306), Expect = e-144, Method: Composition-based stats. Identities = 173/438 (39%), Positives = 242/438 (55%), Gaps = 10/438 (2%) Query: 38 ELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQ 97 E+IR KRDG LS+ +IR F+ + + + QI A+ M I M + E LT A+ Sbjct: 8 EIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRD 67 Query: 98 SGQQLEWPE-AWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLD 156 SG L+W +VDKHSTGGVGD SL+L P +AACG VPMISGRGLGHTGGTLD Sbjct: 68 SGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLD 127 Query: 157 KLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITA 216 KLE+IPGF++ + + ++ G I+GQ+ L PAD YA RD+TATVDS+PLIT Sbjct: 128 KLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITG 187 Query: 217 SILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKP 276 SIL+KKL EGL ALV+DVK G A P E + LA+ +VGV G+R A LT M++ Sbjct: 188 SILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQV 247 Query: 277 LGRCVGHALEVEEALLCMDGAG-PPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALD 335 L G+A+EV EA+ + G P L D+ L +L A A+ A++ A LD Sbjct: 248 LASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLD 307 Query: 336 DGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRAL 395 +G A F RM+AAQ S + LP A + + A +G + + Sbjct: 308 NGKAAEVFGRMVAAQKG--------PSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTR 359 Query: 396 PLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRAL 455 L + + +G GR +A + + VG + +G + P +H A ++A+ Sbjct: 360 ALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAV 419 Query: 456 QEALVLSDRAPFAAPSPF 473 + A++L D+AP + PS + Sbjct: 420 KAAIILDDKAPASTPSVY 437 >2DSJ-A nrPDB Length = 423 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 184/423 (43%), Positives = 235/423 (55%), Gaps = 26/423 (6%) Query: 37 PELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALA 96 IR KR+G + D+ F+ + Q+ A LMA LRG+D EET LT+ +A Sbjct: 4 VAFIREKREGKKHRREDLEAFLLGYLRDEVPDYQVSAWLMAAFLRGLDPEETLWLTETMA 63 Query: 97 QSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLD 156 +SG+ L+ VDKHS+GGVGDKVSLV+ P LAA GC +SGRGL HTGGT+D Sbjct: 64 RSGKVLDLS--GLPHPVDKHSSGGVGDKVSLVVGPILAASGCTFAKMSGRGLAHTGGTID 121 Query: 157 KLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITA 216 KLES+PG+ + + + G I QS L P DG LYA RDVTATV+S+PLI + Sbjct: 122 KLESVPGWRGEMTEAEFLERARRVGLVIAAQSPDLAPLDGKLYALRDVTATVESVPLIAS 181 Query: 217 SILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKP 276 SI+SKKL G ++V+DVK G A E+AR LAKT+V +G G RV A LT+M+ P Sbjct: 182 SIMSKKLAAGARSIVLDVKVGRGAFMKTLEEARLLAKTMVAIGQGAGRRVRALLTSMEAP 241 Query: 277 LGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDD 336 LGR VG+A+EV EA+ + G GP DL ++ L L L G A+ AL+ Sbjct: 242 LGRAVGNAIEVREAIEALKGEGPGDLLEVALALAEEALRLEGLDPALAR------KALEG 295 Query: 337 GSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALP 396 G+AL +F L AQG DP E LLP A E+ L A +G V V A Sbjct: 296 GAALEKFRAFLEAQGGDPRAV---------EDFSLLPLA-EEHPLRAEREGVVREVDAYK 345 Query: 397 LALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQ 456 + L + LG GR R GEP+ GVG LL G R+ RG AL + R L+ Sbjct: 346 VGLAVLALGGGRKRKGEPIDHGVGVYLLKKPGDRVERGEAL--------ALVYHRRRGLE 397 Query: 457 EAL 459 EAL Sbjct: 398 EAL 400 >4GA6-A nrPDB Length = 513 Score = 415 bits (1066), Expect = e-116, Method: Composition-based stats. Identities = 135/452 (29%), Positives = 221/452 (48%), Gaps = 39/452 (8%) Query: 17 DFS-GEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAML 75 +FS GE +P +PE + I+ K G +L + +I V +V+ + +I + + Sbjct: 70 NFSEGETVSVIPAGTPESVRY---IKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFV 126 Query: 76 MAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGV-GDKVSLVLAPALA 134 A+ + G+D++E + LT A+A++G L+ R+ ++D HS GGV G+K ++++ P +A Sbjct: 127 TALEINGLDMDEIAALTIAMAETGDMLDID---RKPIMDVHSIGGVPGNKTNILVVPIVA 183 Query: 135 ACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIV-GQSEQLVP 193 A G +P S R + GT D +E +V S ++++ ++++ G C+V G + L P Sbjct: 184 AAGLTIPKTSSRAITSAAGTADVVEVFA--DVSFSLDEIKRIVEKVGACLVWGGALNLAP 241 Query: 194 ADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAK 253 AD I A + ++D L+ ASI+SKK G +++D+ G E+AR LA+ Sbjct: 242 ADDITIKA-ERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLAR 300 Query: 254 TLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLC-MDGAGPPDLRDLVTTLGGA 312 + +G LG V A+T +P+G VG ALE EAL M G GP L + T L G Sbjct: 301 DFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGI 360 Query: 313 LLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLL 372 LL + G A G L+ G A + + ++ AQG DP + + + + Sbjct: 361 LLEMGGVAPAGT-GKKMAKEILESGKAWEKMKEIIEAQGGDPNI-----------KPEEI 408 Query: 373 PRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLR 432 P + A G V A+ + A AG P G G EL V VG++++ Sbjct: 409 PIGDKTYTFTAATSGYV-------TAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVK 461 Query: 433 RGTPWLRVHRDGPALSGPQSRALQEALVLSDR 464 G P +H + A L +A+VL+ R Sbjct: 462 EGDPLFTIHAEHEA-------RLDQAIVLARR 486 >4GA4-A nrPDB Length = 440 Score = 396 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 130/437 (29%), Positives = 213/437 (48%), Gaps = 38/437 (8%) Query: 31 PEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSV 90 PE + I+ K G +L + +I V +V+ + +I + + A+ + G+D++E + Sbjct: 2 PESVRY---IKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAA 58 Query: 91 LTQALAQSGQQLEWPEAWRQQLVDKHSTGGV-GDKVSLVLAPALAACGCKVPMISGRGLG 149 LT A+A++G L+ R+ ++D HS GGV G+K ++++ P +AA G +P S R + Sbjct: 59 LTIAMAETGDMLDID---RKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAIT 115 Query: 150 HTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIV-GQSEQLVPADGILYAARDVTATV 208 GT D +E +V S ++++ ++++ G C+V G + L PAD I A + ++ Sbjct: 116 SAAGTADVVEVFA--DVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKA-ERALSI 172 Query: 209 DSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAA 268 D L+ ASI+SKK G +++D+ G E+AR LA+ + +G LG V Sbjct: 173 DPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEV 232 Query: 269 ALTAMDKPLGRCVGHALEVEEALLC-MDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGA 327 A+T +P+G VG ALE EAL M G GP L + T L G LL + G A G Sbjct: 233 AITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGILLEMGGVAPAGT-GK 291 Query: 328 ARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADG 387 L+ G A + + ++ AQG DP + + + +P + A G Sbjct: 292 KMAKEILESGKAWEKMKEIIEAQGGDPNI-----------KPEEIPIGDKTYTFTAATSG 340 Query: 388 TVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPAL 447 V A+ + A AG P G G EL V VG++++ G P +H + A Sbjct: 341 YV-------TAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEA- 392 Query: 448 SGPQSRALQEALVLSDR 464 L +A+VL+ R Sbjct: 393 ------RLDQAIVLARR 403 >4GTN-A nrPDB Length = 353 Score = 145 bits (366), Expect = 3e-35, Method: Composition-based stats. Identities = 66/324 (20%), Positives = 127/324 (39%), Gaps = 33/324 (10%) Query: 48 RLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEA 107 L++A + + +++ G+A AQIGA++M +R++G ++E + + + + +++ + Sbjct: 19 HLTQAQMEDVMRSIMQGNATEAQIGALMMGLRMKGESIDEITAAARVMRELAIKIDVSDI 78 Query: 108 WRQQLVDKHSTGGVGD---KVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGF 164 Q LVD TGG G VS + +AA G + RG+ G+ D LE G Sbjct: 79 --QYLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQ-AGI 135 Query: 165 NVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARD---VTATVDSLPLITASILSK 221 N+ +Q + + + G + + A R + + + L +T K Sbjct: 136 NLDLDMQQTERCIREMGVGFLF-APNHHKAMKYAVGPRRELGIRSIFNLLGPLTNPAGVK 194 Query: 222 KLVEG--LSALVVDV-----KFGGAAVF-----PNQEQARELAKTLVGVGASLGLRVAAA 269 + V G L + + G V ++ ++T + + G Sbjct: 195 RFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLASQTYIAELKN-GEVTEWV 253 Query: 270 LTAMDKPLGRCVGHALEVEEALLCMD------GAGPPDLRDLVTTL----GGALLWLSGH 319 L D + L VE++ + G D+ + + GA +++SG Sbjct: 254 LNPEDVNIPSQTLSGLIVEDSNASLKLIKDALGRKKSDIGEKAANMIALNAGAGIYVSGL 313 Query: 320 AGTQAQGAARVAAALDDGSALGRF 343 A + QG A + G AL + Sbjct: 314 ATSYKQGVALAHDIIYGGQALEKM 337 >1KGZ-A nrPDB Length = 345 Score = 137 bits (345), Expect = 9e-33, Method: Composition-based stats. Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 8/151 (5%) Query: 39 LIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQS 98 ++ +++ + AA+V G + +Q+ A L+++++RG EE + AL Sbjct: 16 ILEKLFKSQSMTQEESHQLFAAIVRGELEDSQLAAALISMKMRGERPEEIAGAASALLAD 75 Query: 99 GQQLEWPEAWRQQLVDKHSTGGVGDK---VSLVLAPALAACGCKVPMISGRGLGH-TGGT 154 Q P+ D TGG G +S A A+CG KV R + G+ Sbjct: 76 AQPFPRPD---YDFADIVGTGGDGTNSINISTASAFVAASCGAKVAKHGNRSVCQPLAGS 132 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIV 185 D L++ G + S E + LD C + Sbjct: 133 CDLLQAF-GIRLDMSAEDSRQALDDLNVCFL 162 >1ZYK-A nrPDB Length = 345 Score = 99.1 bits (245), Expect = 3e-21, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 68/150 (45%), Gaps = 8/150 (5%) Query: 38 ELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQ 97 E+++ + L + A++ G + A+L+A+R++G E +A+ + Sbjct: 5 EILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRE 64 Query: 98 SGQQLEWPEAWRQQLVDKHSTGGVG-DKVSLVLAP-ALAACGCKVPMISGRGLGHTGGTL 155 +++ P A +D TGG G V++ A L + V R + G+ Sbjct: 65 LAIKIDVPNA-----IDTAGTGGDGLGTVNVSTASAILLSLVNPVAKHGNRAVSGKSGSA 119 Query: 156 DKLESIPGFNVIQSPEQMQVLLDQAGCCIV 185 D LE++ G+N+I PE+ + L+++ + Sbjct: 120 DVLEAL-GYNIIVPPERAKELVNKTNFVFL 148 >4HKM-A nrPDB Length = 346 Score = 81.7 bits (200), Expect = 7e-16, Method: Composition-based stats. Identities = 70/343 (20%), Positives = 124/343 (36%), Gaps = 35/343 (10%) Query: 33 PKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLT 92 P + ++ + + ++ + ++ G A + A+L +R++ + E + Sbjct: 3 PITPQQALQRTIEHREIFHDEMVDLMRQIMRGEVSDAMVSAILTGLRVKKETIGEIAGAA 62 Query: 93 QALAQSGQQLEWPEAWRQQLVDKHSTGGVGD---KVSLVLAPALAACGCKVPMISGRGLG 149 + + +++E + R+ +VD TGG G +S AA G KV R + Sbjct: 63 TVMREFSRRVEVTD--RRHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVS 120 Query: 150 HTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVD 209 G+ D LE++ G + PEQ+ L Q G + + PA ++ R V Sbjct: 121 SKSGSADALEAL-GAVIELQPEQVAASLAQTGIGFM-YAPVHHPAMKVVAPVR-REMGVR 177 Query: 210 SLPLITASILSKKLVEGLSALVV-----DVKFGGAAVFPNQEQARELA----KTLVGVGA 260 ++ I + + G +++ D+ A V R L + + Sbjct: 178 TIFNILGPLTN---PAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSL 234 Query: 261 SLGLRVAAALT---------------AMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDL 305 G V AM V A E LL + P D+ Sbjct: 235 GAGTLVGELRDGQVHEYEVHPEDFGIAMSASRNLKVADAAESRAMLLQVLDNVPGPALDI 294 Query: 306 VTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLA 348 V GA L+++G A + A G R L DGSA + +A Sbjct: 295 VALNAGAALYVAGVADSIADGIVRARQVLADGSARACLDAYVA 337 >1VQU-A nrPDB Length = 374 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 13/158 (8%) Query: 39 LIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQS 98 L++ DG LS + + ++ + GA+L A+ +G+ +E + + + L Sbjct: 30 LLQQLIDGESLSRSQAAELMQGWLSEAVPPELSGAILTALNFKGVSADELTGMAEVLQSQ 89 Query: 99 GQQ--------LEWPEAWRQQLVDKHSTGGVGDKV---SLVLAPALAACGCKVPMISGRG 147 + L + ++D TGG G S +A AA G V R Sbjct: 90 SKMGTGENYSQLPITNSPFS-IIDTCGTGGDGSSTFNISTAVAFVAAAYGVPVAKHGNRS 148 Query: 148 LGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIV 185 G+ D LE++ G N+ SPE++Q L + G + Sbjct: 149 ASSLTGSADVLEAL-GVNLGASPEKVQAALQEVGITFL 185 >5NOF-A nrPDB Length = 325 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 64/333 (19%), Positives = 114/333 (34%), Gaps = 41/333 (12%) Query: 39 LIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQS 98 L+ DG LS + + G IGA L A++ +G EE + L +A+ S Sbjct: 3 LLAKIVDGKNLSFEEAYELFNELKGSD--GVLIGAYLAALQTKGYTGEELAGLARAMRDS 60 Query: 99 GQQLEWPEAWRQQLVDKHSTGGVGDKV-SLVLAP-ALAACGCKVPMISGRGLGHTGGTLD 156 +L+ ++ D TGG G ++ A + + +V + G+ + Sbjct: 61 AVKLDL-----GKVADTAGTGGDGSSTINVSTASALILSAFTRVAKHGNVSITSKSGSAN 115 Query: 157 KLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITA 216 LE++ G N+ SPE+ + +++ + PA A R + +L + T Sbjct: 116 VLEAL-GLNIRVSPERAREMVESTNFTFI-----FAPAYHP--ALRPIMPVRKALGIKTV 167 Query: 217 SILSKKLVEGLSALVVDVKFGGAAVFPNQEQARE---LAKTLV----------------- 256 + L V + +A E + + LV Sbjct: 168 FNVIGPLANPADPAYQVVGVNSPELLEPVAEALEFLGVERALVVHGSGMDEVSPHRETLV 227 Query: 257 -GVGASLGLRVAAALTAMDKPLG--RCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGAL 313 VG + + +P+ C + G+G + RD + A Sbjct: 228 LEVGNGVERYTLSPEDFGIEPVKPLPCSSPEESAARIKAVLGGSGRREDRDFILVNASAA 287 Query: 314 LWLSGHAGTQAQGAARVAAALDDGSALGRFERM 346 L+ SG A +G AL G L + E + Sbjct: 288 LYASGVAEDFREGLEMAREALGQG-MLEKLEEI 319 >4IJ1-A nrPDB Length = 380 Score = 69.8 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 34/151 (22%), Positives = 58/151 (38%), Gaps = 5/151 (3%) Query: 37 PELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALA 96 P+++ D L+ + ++ G+A+ AQI A +A+ ++ +E L + Sbjct: 29 PQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVML 88 Query: 97 QSGQQLEWPEAWRQQLVDKHSTGGVGDKV---SLVLAPALAACGCKVPMISGRGLGHTGG 153 L + VD TGG G S + A +AA G V R G Sbjct: 89 SHAHPLP-ADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSG 147 Query: 154 TLDKLESIPGFNVIQSPEQMQVLLDQAGCCI 184 D LE++ G + P+ + L + G Sbjct: 148 GADTLEAL-GVRIDLGPDLVARSLAEVGIGF 177 >1V8G-A nrPDB Length = 329 Score = 67.5 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 73/337 (21%), Positives = 125/337 (37%), Gaps = 34/337 (10%) Query: 38 ELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQ 97 + ++ G L E + + A++ G + +L+A+ LRG E + + +A+ + Sbjct: 2 DAVKKAILGEVLEEEEAYEVMRALMAGEVSPVRAAGLLVALSLRGERPHEIAAMARAMRE 61 Query: 98 SGQQLEWPEAWRQQLVDKHSTGGVGD---KVSLVLAPALAACGCKVPMISGRGLGHTGGT 154 + + L R+ L+D TGG G +S + A AA G V R G+ Sbjct: 62 AARPLRVH---RRPLLDIVGTGGDGKGLMNLSTLAALVAAAGGVAVAKHGNRAASSRAGS 118 Query: 155 LDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLI 214 D LE++ G ++ PE++ +++ G + + PA + R V ++ + Sbjct: 119 ADLLEAL-GVDLEAPPERVGEAIEELGFGFLF-ARVFHPAMRHVAPVR-AELGVRTVFNL 175 Query: 215 TASILSKKLVEGLSALVVDV--------------KFGGAAVFPNQEQARELA---KTLVG 257 + + G A V+ V + G + + E A EL +V Sbjct: 176 LGPLTN---PAGADAYVLGVFSPEWLAPMAEALERLGARGLVVHGEGADELVLGENRVVE 232 Query: 258 VGASLGLRVAAALTAMDKPLGRCVGHALEVEEALL--CMDGAGPPDLRDLVTTLGGALLW 315 VG + PL G E AL + G L D V GA + Sbjct: 233 VGKGAYALTPEEVGLKRAPLEALKGGGPEENAALARRLLKGEEKGPLADAVALAAGAGFY 292 Query: 316 LSGHAGTQAQGAARVAAALDDGSA---LGRFERMLAA 349 +G + +G A L G A L R+ L A Sbjct: 293 AAGKTPSLKEGVALAREVLASGEAYLLLERYVAFLRA 329 >4MUO-A nrPDB Length = 328 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Query: 38 ELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQ 97 E+ R K L RG A ++NG ++G +L+A+R++G E +A+ Sbjct: 9 EIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYEAMQN 68 Query: 98 SGQQLEWPEAWRQQLVDKHSTGGVGDKVSL--VLAPALAACGCKVPMIS 144 +L P A + + S G + +L +LA L G V + Sbjct: 69 HTIKLT-PPAGKPMPIVIPSYNGARKQANLTPLLAILLHKLGFPVVVHG 116 >6HIZ-Ck nrPDB Length = 874 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 39/218 (17%), Positives = 63/218 (28%), Gaps = 35/218 (16%) Query: 240 AVFPNQEQARELAKTLVGVGASLGLRVAAALT-------AMDKPLGRCVGHALEVEEALL 292 V P E + LV + + L+ AA+T + + L R + ALE L Sbjct: 170 VVIPKLTSDEEDRRKLVSLWSETTLQAEAAVTKFLFQRGSFESMLHRIITDALEKMSTLA 229 Query: 293 CMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGV 352 G L L R+ + + + L G Sbjct: 230 LGGQEGN---------LALEALKRQTLFKRNDYIQKRLIDVVSNSAYL----------GY 270 Query: 353 DPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRA---LPLALVLHELG---- 405 + + + A LL + + A +G + +V L Sbjct: 271 GDSVWQVFFAAVEANEENLLSDRATTDAIRAAWEGVMREDVVRLPDVTGVVALYLTLVCI 330 Query: 406 --AGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVH 441 +GR E L G E V G R + P + +H Sbjct: 331 RESGRLVPEELKELSSGLEDGVRPGVRKLQQYPLIFLH 368 >1O7X-A nrPDB Length = 377 Score = 32.4 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 316 LSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLL 372 LS + A + L G+A F++ + DP + + ++ L Sbjct: 199 LSDMYSSLTAALAALKGPLHGGAAEEAFKQFIEI--GDPNRVQNWFNDKVVNQKNRL 253 >2ISS-A nrPDB Length = 313 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 30/204 (14%), Positives = 68/204 (33%), Gaps = 30/204 (14%) Query: 78 IRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACG 137 + G+ ++ TS +A+ + A + D GGV S+ + Sbjct: 37 MFKGGVIMDVTSAEQAKIAEEAGAVAV-MALERVPADIRKEGGVARMASIAKIREIMEA- 94 Query: 138 CKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGI 197 +P+++ +GH +L++ G + +SE L PAD Sbjct: 95 VSIPVMAKVRIGHIAEA--------------------KILEELGVDFIDESEVLTPADDR 134 Query: 198 LYAARDVTATVDSLPLITASI----LSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAK 253 + + +P + + +++ EG + + + G V + R + + Sbjct: 135 FH----INKHEFKVPFVCGARDLGEALRRIAEGAAMIRTKGEAGTGNVVEAVKHMRRVME 190 Query: 254 TLVGVGASLGLRVAAALTAMDKPL 277 + V + A + P+ Sbjct: 191 QIKQVTKMEDEELVAYGKEIGAPV 214 >1X7P-A nrPDB Length = 287 Score = 28.6 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 44/123 (35%), Gaps = 10/123 (8%) Query: 45 DGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEW 104 DG R R + V A +LM + + E + + A ++ Sbjct: 65 DGQRELSKWARELLRTVRTEQI--AMAPDLLMELGEKNEAPPEVVAVVEMPADDLDRIPV 122 Query: 105 PEAWRQQLVDK-HSTGGVGDKVSLVLAPALAACGCKVPMISG-----RGLGHTGGTLDKL 158 E + L D+ S G +G + A AL A G V + + + + G+L L Sbjct: 123 REDFLGVLFDRPTSPGNIGSIIR--SADALGAHGLIVAGHAADVYDPKSVRSSTGSLFSL 180 Query: 159 ESI 161 ++ Sbjct: 181 PAV 183 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.125 0.305 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,692,600 Number of Sequences: 36641 Number of extensions: 583677 Number of successful extensions: 2044 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1939 Number of HSP's gapped (non-prelim): 61 length of query: 482 length of database: 10,336,785 effective HSP length: 101 effective length of query: 381 effective length of database: 6,636,044 effective search space: 2528332764 effective search space used: 2528332764 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.2 bits)