BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P19793 (462 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3DZU-A nrPDB 938 0.0 4NQA-A nrPDB 766 0.0 6HN6-A nrPDB 541 e-154 4OC7-A nrPDB 498 e-141 2GL8-A nrPDB 429 e-120 5EC9-A nrPDB 422 e-118 5KYA-B nrPDB 410 e-115 1XIU-A nrPDB 399 e-111 3EYB-A nrPDB 396 e-110 1Z5X-U nrPDB 396 e-110 1H9U-A nrPDB 395 e-110 2Q60-A nrPDB 377 e-105 4OZT-U nrPDB 314 4e-86 2NXX-A nrPDB 312 2e-85 4IQR-A nrPDB 261 5e-70 1YNW-B nrPDB 226 1e-59 1HG4-A nrPDB 216 1e-56 5UAN-B nrPDB 210 1e-54 6FX0-A nrPDB 197 8e-51 4CN5-A nrPDB 196 2e-50 4UMM-F nrPDB 193 1e-49 3CJW-A nrPDB 170 1e-42 4UMM-A nrPDB 168 4e-42 2NLL-A nrPDB 160 1e-39 1LV2-A nrPDB 159 2e-39 1M7W-A nrPDB 156 2e-38 3DZU-D nrPDB 151 5e-37 3TX7-B nrPDB 147 1e-35 4DOR-A nrPDB 145 3e-35 1PK5-A nrPDB 143 1e-34 4NQA-B nrPDB 133 1e-31 4LOG-A nrPDB 129 2e-30 2P7A-A nrPDB 129 3e-30 2EBL-A nrPDB 124 6e-29 4XAJ-A nrPDB 124 7e-29 3CBB-A nrPDB 124 9e-29 1CIT-A nrPDB 122 2e-28 5L0M-A nrPDB 121 6e-28 1YMT-A nrPDB 118 7e-27 5KRB-B nrPDB 114 6e-26 2FF0-A nrPDB 114 7e-26 1HRA-A nrPDB 112 3e-25 3P0U-A nrPDB 112 3e-25 1XDK-B nrPDB 109 2e-24 1XAP-A nrPDB 107 7e-24 2ENV-A nrPDB 104 1e-22 1A6Y-A nrPDB 103 2e-22 1LO1-A nrPDB 100 1e-21 3A9E-B nrPDB 100 1e-21 5K13-A nrPDB 100 1e-21 4OLN-A nrPDB 100 2e-21 3K6P-A nrPDB 100 2e-21 2NLL-B nrPDB 99 3e-21 5M24-A nrPDB 99 3e-21 2XHS-A nrPDB 97 1e-20 4UMM-E nrPDB 97 1e-20 4QJR-A nrPDB 96 5e-20 6IAR-A nrPDB 94 1e-19 1KB2-A nrPDB 94 2e-19 2OCF-A nrPDB 93 3e-19 4PXM-A nrPDB 91 1e-18 4AA6-A nrPDB 91 1e-18 1R0O-B nrPDB 90 2e-18 1LAT-A nrPDB 89 4e-18 2V0V-A nrPDB 89 4e-18 6EU9-A nrPDB 88 9e-18 2J7X-A nrPDB 87 1e-17 5CBX-A nrPDB 87 1e-17 1GDC-A nrPDB 87 2e-17 6CFN-A nrPDB 87 2e-17 5EMP-A nrPDB 85 6e-17 4TNT-A nrPDB 85 6e-17 1GLU-A nrPDB 84 1e-16 2YLY-A nrPDB 84 1e-16 5CC0-A nrPDB 84 1e-16 5CBZ-A nrPDB 83 2e-16 2H79-A nrPDB 81 1e-15 1OVL-B nrPDB 81 1e-15 2C7A-A nrPDB 80 1e-15 1Z5X-E nrPDB 80 2e-15 5KYJ-A nrPDB 80 3e-15 3N00-A nrPDB 79 3e-15 4XAI-A nrPDB 79 4e-15 2NXX-E nrPDB 79 6e-15 3V3Q-A nrPDB 78 1e-14 1R4I-A nrPDB 77 2e-14 3UVV-A nrPDB 76 3e-14 1YJE-A nrPDB 74 1e-13 4OZT-E nrPDB 74 1e-13 5LSG-A nrPDB 74 1e-13 3FAL-B nrPDB 74 2e-13 2XYJ-A nrPDB 73 2e-13 1R20-D nrPDB 72 6e-13 4N1Y-A nrPDB 71 1e-12 3D57-A nrPDB 69 3e-12 1PDU-A nrPDB 69 4e-12 4NUF-A nrPDB 67 2e-11 3F5C-B nrPDB 65 5e-11 5Y44-A nrPDB 65 8e-11 3ET1-A nrPDB 64 1e-10 1OT7-A nrPDB 63 2e-10 1XVP-B nrPDB 61 1e-09 1N4H-A nrPDB 59 6e-09 1S0X-A nrPDB 57 2e-08 5L7E-A nrPDB 57 2e-08 2HCD-A nrPDB 56 3e-08 3G8O-A nrPDB 56 4e-08 3VHU-A nrPDB 56 4e-08 2Q1H-A nrPDB 55 4e-08 4OZR-E nrPDB 55 5e-08 1RJK-A nrPDB 55 5e-08 5GIE-A nrPDB 55 6e-08 1Y9R-A nrPDB 54 1e-07 3P8X-A nrPDB 54 2e-07 5UC1-A nrPDB 54 2e-07 2IHQ-A nrPDB 53 2e-07 3HVL-A nrPDB 53 4e-07 3RY9-A nrPDB 50 2e-06 1XLS-E nrPDB 50 3e-06 4E2J-A nrPDB 49 3e-06 3MNP-A nrPDB 49 4e-06 5NFP-A nrPDB 46 3e-05 5NTQ-A nrPDB 45 8e-05 5NI5-A nrPDB 45 9e-05 3UP0-A nrPDB 32 0.44 6BUW-QI nrPDB 30 2.2 4NQ1-A nrPDB 30 2.9 3ODW-A nrPDB 29 4.6 >3DZU-A nrPDB Length = 467 Score = 938 bits (2424), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 11 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS 70 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS Sbjct: 16 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS 75 Query: 71 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 130 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF Sbjct: 76 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 135 Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC Sbjct: 136 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 195 Query: 191 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV 250 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV Sbjct: 196 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV 255 Query: 251 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 310 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI Sbjct: 256 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 315 Query: 311 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL Sbjct: 316 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 375 Query: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL Sbjct: 376 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 435 Query: 431 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 462 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT Sbjct: 436 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 467 >4NQA-A nrPDB Length = 365 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/365 (100%), Positives = 365/365 (100%) Query: 98 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG 157 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG Sbjct: 1 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG 60 Query: 158 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE 217 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE Sbjct: 61 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE 120 Query: 218 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF Sbjct: 121 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 180 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 337 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA Sbjct: 181 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 240 Query: 338 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY Sbjct: 241 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 300 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA Sbjct: 301 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 360 Query: 458 PHQMT 462 PHQMT Sbjct: 361 PHQMT 365 >6HN6-A nrPDB Length = 282 Score = 541 bits (1394), Expect = e-154, Method: Compositional matrix adjust. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 201 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS 260 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS Sbjct: 21 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS 80 Query: 261 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV 320 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV Sbjct: 81 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV 140 Query: 321 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS 380 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS Sbjct: 141 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS 200 Query: 381 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 440 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK Sbjct: 201 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 260 Query: 441 LIGDTPIDTFLMEMLEAPHQMT 462 LIGDTPIDTFLMEMLEAPHQMT Sbjct: 261 LIGDTPIDTFLMEMLEAPHQMT 282 >4OC7-A nrPDB Length = 254 Score = 498 bits (1281), Expect = e-141, Method: Compositional matrix adjust. Identities = 240/240 (100%), Positives = 240/240 (100%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW Sbjct: 15 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 74 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV Sbjct: 75 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 134 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA Sbjct: 135 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 194 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 462 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT Sbjct: 195 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 254 >2GL8-A nrPDB Length = 241 Score = 429 bits (1104), Expect = e-120, Method: Compositional matrix adjust. Identities = 206/241 (85%), Positives = 225/241 (93%), Gaps = 3/241 (1%) Query: 222 STSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVE 281 + +S +EDMPVERILEAELAVEPKTE+Y + NM +S NDPVTNIC AADKQLFTLVE Sbjct: 4 NATSGHEDMPVERILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHAADKQLFTLVE 60 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG 341 WAKRIPHFS+L L+DQVILLRAGWNELLIASFSHRS++V+DGILLATGLHVHR+SAHSAG Sbjct: 61 WAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAG 120 Query: 342 VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLE 401 VG+IFDRVLTELVSKM+DMQMDK+ELGCLRAIVLFNPD+KGLSNP+EVE LREKVYA+LE Sbjct: 121 VGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLE 180 Query: 402 AYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQM 461 AY K KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE P Q+ Sbjct: 181 AYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQI 240 Query: 462 T 462 T Sbjct: 241 T 241 >5EC9-A nrPDB Length = 210 Score = 422 bits (1085), Expect = e-118, Method: Compositional matrix adjust. Identities = 210/228 (92%), Positives = 210/228 (92%), Gaps = 18/228 (7%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 DMPVERILEAELAVEP DPVTNICQAADKQLFTLVEWAKRIPH Sbjct: 1 DMPVERILEAELAVEP------------------DPVTNICQAADKQLFTLVEWAKRIPH 42 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 348 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR Sbjct: 43 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 102 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 408 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY Sbjct: 103 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 162 Query: 409 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE Sbjct: 163 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 210 >5KYA-B nrPDB Length = 256 Score = 410 bits (1054), Expect = e-115, Method: Compositional matrix adjust. Identities = 205/234 (87%), Positives = 215/234 (91%), Gaps = 2/234 (0%) Query: 226 ANEDMPVERILEAELAVEPKTE--TYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWA 283 A E+MPV+RILEAELAVE K++ G + SSPNDPVTNICQAADKQLFTLVEWA Sbjct: 4 APEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWA 63 Query: 284 KRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVG 343 KRIPHFS LPLDDQVILLRAGWNELLIASFSHRSI V+DGILLATGLHVHRNSAHSAGVG Sbjct: 64 KRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVG 123 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY 403 AIFDRVLTELVSKMRDM+MDKTELGCLRAI+LFNPD+KGLSNP+EVE LREKVYASLE Y Sbjct: 124 AIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETY 183 Query: 404 CKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 CK KYPEQ GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA Sbjct: 184 CKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 237 >1XIU-A nrPDB Length = 230 Score = 399 bits (1025), Expect = e-111, Method: Compositional matrix adjust. Identities = 192/233 (82%), Positives = 207/233 (88%), Gaps = 8/233 (3%) Query: 226 ANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKR 285 AN DMPVE+ILEAELAV+PK +TY++A DPVTNICQAADKQLFTLVEWAKR Sbjct: 2 ANNDMPVEQILEAELAVDPKIDTYIDAQ--------KDPVTNICQAADKQLFTLVEWAKR 53 Query: 286 IPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI 345 IPHF+ELPL+DQVILLRAGWNELLIA FSHRSI KDGILLATGLHVHR+SAH AGVG I Sbjct: 54 IPHFTELPLEDQVILLRAGWNELLIAGFSHRSIMAKDGILLATGLHVHRSSAHQAGVGTI 113 Query: 346 FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK 405 FDRVLTELV+KMRDM+MDKTELGCLRA+VLFNPD+KGL+ EVE LREKVYASLE Y K Sbjct: 114 FDRVLTELVAKMRDMKMDKTELGCLRAVVLFNPDAKGLTAVQEVEQLREKVYASLEEYTK 173 Query: 406 HKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 458 +YPE+PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD PIDTFLMEMLE P Sbjct: 174 SRYPEEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDQPIDTFLMEMLENP 226 >3EYB-A nrPDB Length = 219 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 191/227 (84%), Positives = 206/227 (90%), Gaps = 8/227 (3%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 DMPVE+I EAE+AVEPK VE PNDPVTNICQAADKQL TLVEWAKRIPH Sbjct: 1 DMPVEKIQEAEMAVEPKDGNMVE--------QPNDPVTNICQAADKQLVTLVEWAKRIPH 52 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 348 FS+LP+DDQVILLRAGWNELLIA+FSHRSI VKDGILLA+GLHVHR+SAH AGVG IFDR Sbjct: 53 FSDLPIDDQVILLRAGWNELLIAAFSHRSIDVKDGILLASGLHVHRSSAHQAGVGTIFDR 112 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 408 VLTELV+KMRDM+MDKTELGCLRAIVLFNPD+KGL++P+ VE+LREKVYASLE YCK +Y Sbjct: 113 VLTELVAKMRDMKMDKTELGCLRAIVLFNPDAKGLTDPSLVESLREKVYASLEEYCKQQY 172 Query: 409 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML Sbjct: 173 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 219 >1Z5X-U nrPDB Length = 262 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/259 (72%), Positives = 221/259 (85%), Gaps = 10/259 (3%) Query: 199 GMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNP 258 G KREAVQEERQR K+++ENEVESTS++ DMP+ERILEAEL VEPK E Sbjct: 10 GPKREAVQEERQRNKEKSENEVESTSNSQNDMPIERILEAELRVEPKNEDI--------- 60 Query: 259 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI 318 DPV++ICQAAD+QL+ L+EWAK IPHF+ELP++DQVILL++GWNELLIA FSHRS+ Sbjct: 61 -DSRDPVSDICQAADRQLYQLIEWAKHIPHFTELPVEDQVILLKSGWNELLIAGFSHRSM 119 Query: 319 AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP 378 +VKDGI+LATGL VHRN AH AGVGAIFDRVLTELV+KMR+M+MDKTELGCLR+IVLFNP Sbjct: 120 SVKDGIMLATGLVVHRNCAHQAGVGAIFDRVLTELVAKMREMKMDKTELGCLRSIVLFNP 179 Query: 379 DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF 438 ++KGL + +VE LREKVYA LE YC+ YP+Q GRFAKLLLRLPALRSIGLKCLEHLFF Sbjct: 180 EAKGLKSTQQVENLREKVYAILEEYCRQTYPDQSGRFAKLLLRLPALRSIGLKCLEHLFF 239 Query: 439 FKLIGDTPIDTFLMEMLEA 457 FKL+G+T ID+FL+ MLE+ Sbjct: 240 FKLVGNTSIDSFLLSMLES 258 >1H9U-A nrPDB Length = 224 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 197/224 (87%), Positives = 206/224 (91%), Gaps = 2/224 (0%) Query: 230 MPVERILEAELAVEPKTE--TYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIP 287 MPV+RILEAELAVE K++ G + SSPNDPVTNICQAADKQLFTLVEWAKRIP Sbjct: 1 MPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIP 60 Query: 288 HFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFD 347 HFS LPLDDQVILLRAGWNELLIASFSHRSI V+DGILLATGLHVHRNSAHSAGVGAIFD Sbjct: 61 HFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFD 120 Query: 348 RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHK 407 RVLTELVSKMRDM+MDKTELGCLRAI+LFNPD+KGLSNP+EVE LREKVYASLE YCK K Sbjct: 121 RVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQK 180 Query: 408 YPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 451 YPEQ GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL Sbjct: 181 YPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 224 >2Q60-A nrPDB Length = 258 Score = 377 bits (969), Expect = e-105, Method: Compositional matrix adjust. Identities = 184/234 (78%), Positives = 202/234 (86%), Gaps = 4/234 (1%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 S+ N+DMPV++ILEAEL +PK E V + NDPV+NIC+AAD+QL TLVEW Sbjct: 22 ASNPNDDMPVDKILEAELISDPKVEQVVP----FEQVNENDPVSNICKAADRQLVTLVEW 77 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AKRIPHFS LPL+DQVILLRAGWNELLIASFSHRSI VKD ILLA+GLHVHR+SAH AGV Sbjct: 78 AKRIPHFSSLPLEDQVILLRAGWNELLIASFSHRSIDVKDSILLASGLHVHRHSAHQAGV 137 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 G IFDRVLTELVSKMRDM MDKTELGCLRA+VLFNPD K S+ A +E+LREKVYASLEA Sbjct: 138 GPIFDRVLTELVSKMRDMMMDKTELGCLRAVVLFNPDVKNPSDSAHIESLREKVYASLEA 197 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 YC+ KYP+QPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPID FLM MLE Sbjct: 198 YCRSKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDKFLMNMLE 251 >4OZT-U nrPDB Length = 195 Score = 314 bits (805), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 145/193 (75%), Positives = 167/193 (86%) Query: 263 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKD 322 + V NICQA + QL+ LVEWAK IPHFS LP++DQV+LLRAGWNELLIA+FSHRS+ V+D Sbjct: 1 NAVANICQATNSQLYQLVEWAKHIPHFSSLPIEDQVLLLRAGWNELLIAAFSHRSVEVRD 60 Query: 323 GILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKG 382 GI+L G+ VHRNSAH AGVG IFDRVLTELV+KMRDM MD+TELG LR+I+LFNP+ +G Sbjct: 61 GIVLGAGITVHRNSAHQAGVGTIFDRVLTELVAKMRDMNMDRTELGSLRSIILFNPEVRG 120 Query: 383 LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L + EVE LREKVYA+LE Y + PE+PGRFAKLLLRLPALRSIGLKCLEHLFFFKLI Sbjct: 121 LKSGQEVELLREKVYAALEEYTRVTRPEEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 180 Query: 443 GDTPIDTFLMEML 455 GD PIDTFLM+ML Sbjct: 181 GDIPIDTFLMDML 193 >2NXX-A nrPDB Length = 235 Score = 312 bits (799), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 153/234 (65%), Positives = 186/234 (79%), Gaps = 5/234 (2%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 TS+ DMP+ERI+EAE VE + + L + N V NICQA KQLF LV+W Sbjct: 2 TSNLQADMPLERIIEAEKRVECN-----DPLVALVVNENNTTVNNICQATHKQLFQLVQW 56 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AK +PHF+ LPL DQV LLRAGWNELLIA+FSHRS+ +D I+LATGL V++++AH+ GV Sbjct: 57 AKLVPHFTSLPLTDQVQLLRAGWNELLIAAFSHRSMQAQDAIVLATGLTVNKSTAHAVGV 116 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 G I+DRVL+ELV+KM++M+MDKTELGCLRAI+L+NPD +G+ + EVE LREK+Y LE Sbjct: 117 GNIYDRVLSELVNKMKEMKMDKTELGCLRAIILYNPDVRGIKSVQEVEMLREKIYGVLEE 176 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 Y + +P +PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD PIDTFLMEMLE Sbjct: 177 YTRTTHPNEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDVPIDTFLMEMLE 230 >4IQR-A nrPDB Length = 338 Score = 261 bits (667), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 139/323 (43%), Positives = 198/323 (61%), Gaps = 8/323 (2%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +CAICGDR++GKHYG SC+GCKGFF+R+VRK+ Y+CR ++ C++DK +RN+C+YCR + Sbjct: 20 LCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLK 79 Query: 194 KCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMP-VERILEAELAVEPKTETYVEA 252 KC GMK+EAVQ ER R R +S + +P + +L+AE+ T Sbjct: 80 KCFRAGMKKEAVQNERDRISTRR------SSYEDSSLPSINALLQAEVLSRQITSPVSGI 133 Query: 253 NMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 N + + ++C++ +QL LVEWAK IP F ELPLDDQV LLRA E L+ Sbjct: 134 NGDIRAKKIA-SIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLG 192 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 + RS+ KD +LL V R+ A + + R+L ELV +++Q+D E L+A Sbjct: 193 ATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKA 252 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I+ F+PD+KGLS+P +++ LR +V SLE Y + + GRF +LLL LP L+SI + Sbjct: 253 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 312 Query: 433 LEHLFFFKLIGDTPIDTFLMEML 455 +E + F KL G ID L EML Sbjct: 313 IEQIQFIKLFGMAKIDNLLQEML 335 >1YNW-B nrPDB Length = 99 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 99/99 (100%), Positives = 99/99 (100%) Query: 130 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY Sbjct: 1 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 60 Query: 190 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE 228 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE Sbjct: 61 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE 99 >1HG4-A nrPDB Length = 279 Score = 216 bits (551), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 113/256 (44%), Positives = 156/256 (60%), Gaps = 32/256 (12%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDP-----VTNICQAADKQLF 277 T+S + D +ERI+EAE E + + + P S P V+ +CQ +KQLF Sbjct: 2 TNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLF 61 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIA-------------------------- 311 +VE+A+ +PHF+++PLDDQVILL+A W ELLIA Sbjct: 62 QMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDG 121 Query: 312 SFSHRSIAVK-DGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370 SF RS ++ + L HRNSA AGV AIFDR+L+EL KM+ + +D+ EL CL Sbjct: 122 SFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCL 181 Query: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430 +AI+L+NPD +G+ + AE+E REKVYA L+ +C+ ++P GRFA+LLLRLPALRSI L Sbjct: 182 KAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISL 241 Query: 431 KCLEHLFFFKLIGDTP 446 KC +HLF F++ D P Sbjct: 242 KCQDHLFLFRITSDRP 257 >5UAN-B nrPDB Length = 397 Score = 210 bits (534), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 118/338 (34%), Positives = 186/338 (55%), Gaps = 26/338 (7%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D+SSG HYGV +CEGCKGFF+R+++K++ YTC +K+C+I+K RNRCQYCR QK Sbjct: 30 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQK 89 Query: 195 CLAMGMKREAVQEERQRGKDRNENEVESTSS----ANEDMPVERILEAELAVEP------ 244 C +GM +E+V+ +R + K + ++ E T S A D E+I +A P Sbjct: 90 CFEVGMSKESVRNDRNK-KKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLG 148 Query: 245 ------KTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQV 298 + V ++GL + A K + +VE+AKR+P F+ L + DQ+ Sbjct: 149 KYTTNSSADHRVRLDLGL--------WDKFSELATKCIIKIVEFAKRLPGFTGLTIADQI 200 Query: 299 ILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMR 358 LL+A ++LI R +D + + GL ++R H+AG G + D V T +++ Sbjct: 201 TLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFT-FANQLL 259 Query: 359 DMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKL 418 ++MD TE G L AI L D + L P +V+ L+E + +L+ Y + + P +P F K+ Sbjct: 260 PLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKI 319 Query: 419 LLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 L+++ LRSI K E + K+ + + EMLE Sbjct: 320 LMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 357 >6FX0-A nrPDB Length = 454 Score = 197 bits (501), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 113/340 (33%), Positives = 177/340 (52%), Gaps = 24/340 (7%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D+SSG HYGV SCEGCKGFF+R+++K++ YTC +K+C+I+K RNRCQYCR QK Sbjct: 90 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 149 Query: 195 CLAMGMKREAVQEERQRGKDRN---------------ENEVESTSSANEDMPVERILEAE 239 C +GM +EAV+ +R + K E + S A+++ + Sbjct: 150 CFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGK 209 Query: 240 LAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVI 299 + V+ ++GL + A K + +VE+AKR+P F+ L + DQ+ Sbjct: 210 YTTNSSADHRVQLDLGL--------WDKFSELATKCIIKIVEFAKRLPGFTGLSIADQIT 261 Query: 300 LLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRD 359 LL+A ++L+ R +D + + GL ++R H+AG G + D V ++ Sbjct: 262 LLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA-FAGQLLP 320 Query: 360 MQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLL 419 ++MD TE G L AI L D L P +V+ L+E + +L Y + + P QP F ++L Sbjct: 321 LEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRML 380 Query: 420 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 +++ LR I K E K+ P+ + EMLE P Sbjct: 381 MKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE 420 >4CN5-A nrPDB Length = 87 Score = 196 bits (497), Expect = 2e-50, Method: Composition-based stats. Identities = 83/83 (100%), Positives = 83/83 (100%) Query: 130 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY Sbjct: 5 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 64 Query: 190 CRYQKCLAMGMKREAVQEERQRG 212 CRYQKCLAMGMKREAVQEERQRG Sbjct: 65 CRYQKCLAMGMKREAVQEERQRG 87 >4UMM-F nrPDB Length = 264 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 111/252 (44%), Positives = 159/252 (63%), Gaps = 21/252 (8%) Query: 225 SANEDMPVERILEAELAVEPKTETYVEANMGLNPSSP---NDPVTNICQAADKQLFTLVE 281 +A +++ +ER+LE E V +E + +G + + P PV+++CQ +KQ+ LV Sbjct: 1 AAVQELSIERLLEMESLVADPSEEFQFLRVGPDSNVPPKFRAPVSSLCQIGNKQIAALVV 60 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV----KDGI------------- 324 WA+ IPHFS+L ++DQ++L++ WNELL+ + + RS+ +DG+ Sbjct: 61 WARDIPHFSQLEMEDQILLIKGSWNELLLFAIAWRSMEFLTEERDGVDGTGNRTTSPPQL 120 Query: 325 -LLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL 383 L G+ +HRNSA AGVG IFDRVL+EL KMR +++D+ E L+AI+L NPD KGL Sbjct: 121 MCLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRTLRVDQAEYVALKAIILLNPDVKGL 180 Query: 384 SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 443 N EVE LREK++ L+ YC+ + GRFA LLLRLPALRSI LK EHLFFF L+ Sbjct: 181 KNRQEVEVLREKMFLCLDEYCRRSRSSEEGRFAALLLRLPALRSISLKSFEHLFFFHLVA 240 Query: 444 DTPIDTFLMEML 455 DT I ++ + L Sbjct: 241 DTSIAGYIRDAL 252 >3CJW-A nrPDB Length = 244 Score = 170 bits (431), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 92/216 (42%), Positives = 131/216 (60%), Gaps = 7/216 (3%) Query: 245 KTETYVEANMGLNPSSPNDP--VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLR 302 + E Y + G PN+ + NIC+ A + LF+ VEWA+ IP F +L + DQV LLR Sbjct: 17 RAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLR 76 Query: 303 AGWNELLIASFSHRSIAVKDG-ILLATGLHVHRNSAHSAGVGAIFD--RVLTELVSKMRD 359 W+EL + + + S+ + +L A GLH SA V A D R+ E V K++ Sbjct: 77 LTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR--VVAFMDHIRIFQEQVEKLKA 134 Query: 360 MQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLL 419 + +D E CL+AIVLF D+ GLS+ A VE+L+EK +LE Y + +YP QP RF KLL Sbjct: 135 LHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL 194 Query: 420 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 LRLP+LR++ +E LFF +L+G TPI+T + +ML Sbjct: 195 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 230 >4UMM-A nrPDB Length = 78 Score = 168 bits (426), Expect = 4e-42, Method: Composition-based stats. Identities = 68/78 (87%), Positives = 75/78 (96%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 KH+C+ICGDR+SGKHYGVYSCEGCKGFFKRTVRKDLTY CR+ ++C+IDKRQRNRCQYCR Sbjct: 1 KHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACREERNCIIDKRQRNRCQYCR 60 Query: 192 YQKCLAMGMKREAVQEER 209 YQKCLA GMKREAVQEER Sbjct: 61 YQKCLACGMKREAVQEER 78 >2NLL-A nrPDB Length = 66 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 66/66 (100%), Positives = 66/66 (100%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK Sbjct: 1 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 60 Query: 195 CLAMGM 200 CLAMGM Sbjct: 61 CLAMGM 66 >1LV2-A nrPDB Length = 229 Score = 159 bits (403), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 85/191 (44%), Positives = 119/191 (62%), Gaps = 1/191 (0%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 + ++C++ +QL LVEWAK IP F ELPLDDQV LLRA E L+ + RS+ KD + Sbjct: 37 IGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDIL 96 Query: 325 LLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLS 384 LL +HRNS + + +RVL ELV +++Q+D E CL+AIV F+PD+KGLS Sbjct: 97 LLGNNYVIHRNSCE-VEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLS 155 Query: 385 NPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD 444 +P +++ +R +V LE Y + + GRF +LLL LP L+SI + +E + F KL G Sbjct: 156 DPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGM 215 Query: 445 TPIDTFLMEML 455 ID L EML Sbjct: 216 VKIDNLLQEML 226 >1M7W-A nrPDB Length = 250 Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 87/201 (43%), Positives = 122/201 (60%), Gaps = 6/201 (2%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 +T++C++ +QL LVEWAK IP F EL LDDQV LLRA E L+ + RS+ KD + Sbjct: 43 ITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVL 102 Query: 325 LLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLS 384 LL V R+ A + + R+L ELV +++Q+D E CL+AI+ F+PD+KGLS Sbjct: 103 LLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLS 162 Query: 385 NPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD 444 +P +++ LR +V SLE Y + + GRF +LLL LP L+SI + +E + F KL G Sbjct: 163 DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGM 222 Query: 445 TPIDTFLMEML------EAPH 459 ID L EML +APH Sbjct: 223 AKIDNLLQEMLLGGSASDAPH 243 >3DZU-D nrPDB Length = 419 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 108/371 (29%), Positives = 178/371 (47%), Gaps = 52/371 (14%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD++SG HYGV++CEGCKGFF+RT+R L Y R + +C I K+ RN+CQYCR+QK Sbjct: 53 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 111 Query: 195 CLAMGMKREAVQEER--QRGKDRNENEVEST------SSANEDMPVERILEAELAVEPKT 246 CLA+GM A++ R Q K++ E+ S SA+ + + ++ + P T Sbjct: 112 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 171 Query: 247 ETYVEANMGLNPSSPNDP-----VTNICQAADKQLFT----------------------- 278 + A + ++ P + ++ DK F Sbjct: 172 KAKARAILT-GKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFR 230 Query: 279 -------LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLH 331 + E+AK IP F L L+DQV LL+ G +E++ + S+ KDG+L++ G Sbjct: 231 SVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLA--SLMNKDGVLISEGQG 288 Query: 332 VHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 + D + E K +++D ++L A+++ + D GL N + Sbjct: 289 FMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPI 348 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 E +++ + +LE K +PE FAKLL ++ LR I EH+ ++I T D Sbjct: 349 EDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEHVQLLQVIKKTETDM 405 Query: 450 FLMEMLEAPHQ 460 L +L+ ++ Sbjct: 406 SLHPLLQEIYK 416 >3TX7-B nrPDB Length = 352 Score = 147 bits (371), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 122/195 (62%), Gaps = 6/195 (3%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV-KDG-IL 325 +C+ AD+ LF++VEWA+ F EL +DDQ+ LL+ W+ELLI +R + K+G I Sbjct: 156 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIF 215 Query: 326 LATGLHVHRNSAHSAGVGAIFDRVLT---ELVSKMRDMQMDKTELGCLRAIVLFNPDSKG 382 L TG V S ++ GA + +++ ELV+K+R +Q D+ E CL+ +VLF+ D K Sbjct: 216 LVTGQQVDY-SIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 274 Query: 383 LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L N VE ++E+V A+L Y YP+Q +F +LLLRLP +R+I ++ E+L++ L Sbjct: 275 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 334 Query: 443 GDTPIDTFLMEMLEA 457 GD P + L+EML A Sbjct: 335 GDVPYNNLLIEMLHA 349 >4DOR-A nrPDB Length = 255 Score = 145 bits (366), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 122/195 (62%), Gaps = 6/195 (3%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV-KDG-IL 325 +C+ AD+ LF++VEWA+ F EL +DDQ+ LL+ W+ELLI +R + K+G I Sbjct: 59 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIF 118 Query: 326 LATGLHVHRNSAHSAGVGAIFDRVLT---ELVSKMRDMQMDKTELGCLRAIVLFNPDSKG 382 L TG V S ++ GA + +++ ELV+K+R +Q D+ E CL+ +VLF+ D K Sbjct: 119 LVTGQQVDY-SIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 177 Query: 383 LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L N VE ++E+V A+L Y YP+Q +F +LLLRLP +R+I ++ E+L++ L Sbjct: 178 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 237 Query: 443 GDTPIDTFLMEMLEA 457 GD P + L+EML A Sbjct: 238 GDVPYNNLLIEMLHA 252 >1PK5-A nrPDB Length = 248 Score = 143 bits (361), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 86/225 (38%), Positives = 132/225 (58%), Gaps = 11/225 (4%) Query: 243 EPKTETYVEANMGLNPSSPN-----DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQ 297 EP+ + + A + S+ N +C+ AD+ LF++VEWA+ F EL +DDQ Sbjct: 22 EPQVQAKIMAYLQQEQSNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQ 81 Query: 298 VILLRAGWNELLIASFSHRSIAV-KDG-ILLATGLHVHRNSAHSAGVGAIFDRVLT---E 352 + LL+ W+ELLI +R +A K+G I L TG HV ++ S A F+ +L+ E Sbjct: 82 MKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSTIISHTEVA-FNNLLSLAQE 140 Query: 353 LVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQP 412 LV ++R +Q D+ E CL+ +VLF+ D K L N VE ++E+V A+L Y YP+Q Sbjct: 141 LVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENLQLVEGVQEQVNAALLDYTVCNYPQQT 200 Query: 413 GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +F +LLLRLP LR+I + ++L++ + GD P + L+EML A Sbjct: 201 EKFGQLLLRLPELRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHA 245 >4NQA-B nrPDB Length = 391 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 99/360 (27%), Positives = 161/360 (44%), Gaps = 51/360 (14%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKD--LTYTCRDNKDCLIDKRQRNRCQYC 190 +C +CGD++SG HY V SCEGCKGFF+R+V + Y CR C +D R +CQ C Sbjct: 15 ELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQC 74 Query: 191 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPV------------------ 232 R +KC GM+ + V E Q K + + + S + PV Sbjct: 75 RLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGG 134 Query: 233 ----------ERILEAELAVEPKTETYVEANMGLNPSSPND-------PVTNICQAAD-- 273 ++ A E + V A + N S +D P+ Q+ D Sbjct: 135 SEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDAR 194 Query: 274 KQLFT------------LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVK 321 +Q F +V++AK++P F +L +DQ+ LL+A E+++ + R Sbjct: 195 QQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHET 254 Query: 322 DGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSK 381 + I ++ H AG+ F + E MR + +D E L AI +F+ D Sbjct: 255 ECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRP 314 Query: 382 GLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 + P VEAL++ +L +Y + K P+ RF ++L++L +LR++ E +F +L Sbjct: 315 NVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRL 374 >4LOG-A nrPDB Length = 574 Score = 129 bits (325), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 75/193 (38%), Positives = 113/193 (58%), Gaps = 1/193 (0%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 + +I + + + LF V+WAK +P FS LP DQVILL W+EL + S+ + Sbjct: 375 LDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCP 434 Query: 325 LLATGLHVHRNSAHS-AGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL 383 LLA A + ++ RVL E +S+ R + +D TE C++A+VLF P+++GL Sbjct: 435 LLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGL 494 Query: 384 SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 443 +P VEAL+++ L + K +P QP RF KLLL LP+LR I + +E LFF K IG Sbjct: 495 KDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIG 554 Query: 444 DTPIDTFLMEMLE 456 +TP++ L +M + Sbjct: 555 NTPMEKLLSDMFK 567 >2P7A-A nrPDB Length = 251 Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 115/200 (57%), Gaps = 1/200 (0%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S +T +C AD++L ++ WAK IP FS L L DQ+ LL++ W E+LI +RS Sbjct: 51 PDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRS 110 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFN 377 ++ +D ++ A + + + AG+ + + +L +LV K + M+++K E L+AI L N Sbjct: 111 LSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMKLEKEEFVTLKAIALAN 169 Query: 378 PDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLF 437 DS + + V+ L++ ++ +L+ Y ++ E P R K+L+ LP LR K ++H + Sbjct: 170 SDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFY 229 Query: 438 FFKLIGDTPIDTFLMEMLEA 457 KL G P+ +EMLEA Sbjct: 230 NIKLEGKVPMHKLFLEMLEA 249 >2EBL-A nrPDB Length = 89 Score = 124 bits (312), Expect = 6e-29, Method: Composition-based stats. Identities = 49/72 (68%), Positives = 63/72 (87%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD+SSGKHYG ++CEGCK FFKR+VR++LTYTCR N++C ID+ RN+CQYCR +K Sbjct: 10 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKK 69 Query: 195 CLAMGMKREAVQ 206 CL +GM+REAVQ Sbjct: 70 CLKVGMRREAVQ 81 >4XAJ-A nrPDB Length = 576 Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 71/200 (35%), Positives = 112/200 (56%), Gaps = 10/200 (5%) Query: 267 NICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILL 326 ++C++A + LF ++WAK +P FS L L DQ++LL W EL + + +I V LL Sbjct: 377 SVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLL 436 Query: 327 ATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNP------ 378 A ++ ++ S + I + L E+V++ R +++D TE CL+ IV F Sbjct: 437 AVS-GMNGDNTDSQRLTLIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSG 495 Query: 379 -DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLF 437 + + N A + AL+++ +L +Y +YP QP RF KLLL LPALRSI +E +F Sbjct: 496 SELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPVRFGKLLLLLPALRSISPSTIEEVF 555 Query: 438 FFKLIGDTPIDTFLMEMLEA 457 F K IG+ PI L +M ++ Sbjct: 556 FKKTIGNVPITRLLSDMYKS 575 >3CBB-A nrPDB Length = 78 Score = 124 bits (311), Expect = 9e-29, Method: Composition-based stats. Identities = 47/76 (61%), Positives = 64/76 (84%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +CAICGDR++GKHYG SC+GCKGFF+R+VRK+ Y+CR ++ C++DK +RN+C+YCR + Sbjct: 2 LCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLK 61 Query: 194 KCLAMGMKREAVQEER 209 KC GMK+EAVQ ER Sbjct: 62 KCFRAGMKKEAVQNER 77 >1CIT-A nrPDB Length = 89 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 49/79 (62%), Positives = 64/79 (81%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 CA+CGD +S +HYGV +CEGCKGFFKRTV+K Y C NKDC +DKR+RNRCQ+CR+QK Sbjct: 3 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKSAKYICLANKDCPVDKRRRNRCQFCRFQK 62 Query: 195 CLAMGMKREAVQEERQRGK 213 CLA+GM +E V+ + +G+ Sbjct: 63 CLAVGMVKEVVRTDSLKGR 81 >5L0M-A nrPDB Length = 112 Score = 121 bits (304), Expect = 6e-28, Method: Composition-based stats. Identities = 48/81 (59%), Positives = 64/81 (79%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + +C +CGD+ SG HYG+ +CE CKGFFKRTV+ + YTC +N++C IDK QR RC YCR Sbjct: 8 EELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCR 67 Query: 192 YQKCLAMGMKREAVQEERQRG 212 +QKCL++GMK EAV+ +R RG Sbjct: 68 FQKCLSVGMKLEAVRADRMRG 88 >1YMT-A nrPDB Length = 246 Score = 118 bits (295), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 112/200 (56%), Gaps = 4/200 (2%) Query: 264 PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV--K 321 P + +C+ AD+ ++V+WA+R F EL + DQ+ LL+ W+ELL+ +R + + Sbjct: 46 PFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNSWSELLVLDHIYRQVQYGKE 105 Query: 322 DGILLATGLHVHRNSAHSAGVGAIFDRVL--TELVSKMRDMQMDKTELGCLRAIVLFNPD 379 D ILL TG V ++ + VL ELV ++ +Q+D+ E CL+ ++LF+ D Sbjct: 106 DSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLD 165 Query: 380 SKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFF 439 K L+N + V+ +EK A+L Y YP +F +LLL L +R++ ++ E+L+ Sbjct: 166 VKFLNNHSLVKDAQEKANAALLDYTLSHYPHSGDKFQQLLLSLVEVRALSMQAKEYLYHK 225 Query: 440 KLIGDTPIDTFLMEMLEAPH 459 L + P + L+EML+A Sbjct: 226 HLGNEMPRNNLLIEMLQAKQ 245 >5KRB-B nrPDB Length = 84 Score = 114 bits (286), Expect = 6e-26, Method: Composition-based stats. Identities = 44/81 (54%), Positives = 60/81 (74%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + C ICGDR++G HYG+ SCEGCKGFFKR++ Y C +K+C++ ++QRNRCQYCR Sbjct: 1 QRTCLICGDRATGLHYGIISCEGCKGFFKRSISNKRVYRCSRDKNCVMSRKQRNRCQYCR 60 Query: 192 YQKCLAMGMKREAVQEERQRG 212 KCL MGM R+A++E+ G Sbjct: 61 LLKCLQMGMNRKAIREDGMPG 81 >2FF0-A nrPDB Length = 102 Score = 114 bits (286), Expect = 7e-26, Method: Composition-based stats. Identities = 45/79 (56%), Positives = 61/79 (77%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +C +CGD+ SG HYG+ +CE CKGFFKRTV+ + YTC +++ C IDK QR RC +CR+Q Sbjct: 3 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 62 Query: 194 KCLAMGMKREAVQEERQRG 212 KCL +GM+ EAV+ +R RG Sbjct: 63 KCLTVGMRLEAVRADRMRG 81 >1HRA-A nrPDB Length = 80 Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats. Identities = 42/72 (58%), Positives = 59/72 (81%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D+SSG HYGV +CEGCKGFF+R+++K++ YTC +K+C+I+K RNRCQYCR QK Sbjct: 8 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQK 67 Query: 195 CLAMGMKREAVQ 206 C +GM +E+V+ Sbjct: 68 CFEVGMSKESVR 79 >3P0U-A nrPDB Length = 249 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 70/212 (33%), Positives = 106/212 (50%), Gaps = 16/212 (7%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 V IC++A + LF + WA+ IP F L D L+RA WNEL + + + Sbjct: 36 VHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLST 95 Query: 325 LLATGLHVHRNSAHSAGVGAIFDRV---------LTELVSKMRDMQMDKTELGCLRAIVL 375 +LA ++ +NS + DR+ L E + M + +D E L+AIVL Sbjct: 96 ILAAIVNHLQNSIQEDKLSG--DRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVL 153 Query: 376 FNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEH 435 F+PD GL++ +++E +E L+ Y + Y E R A++L+RLPALR + E Sbjct: 154 FSPDHPGLTSTSQIEKFQEAAQMELQDYVQATYSEDTYRLARILVRLPALRLMSSNITEE 213 Query: 436 LFFFKLIGDTPIDTFL-----MEMLEAPHQMT 462 LFF LIG+ ID+ + ME E Q+T Sbjct: 214 LFFTGLIGNVSIDSIIPYILKMETAEYNGQIT 245 >1XDK-B nrPDB Length = 303 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 62/187 (33%), Positives = 103/187 (55%), Gaps = 1/187 (0%) Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 + A K + +VE+AKR+P F+ L + DQ+ LL+A ++LI R +D + + G Sbjct: 78 ELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG 137 Query: 330 LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 L ++R H+AG G + D V T +++ ++MD TE G L AI L D + L P +V Sbjct: 138 LTLNRTQMHNAGFGPLTDLVFT-FANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKV 196 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 + L+E + +L+ Y + + P +P F K+L+++ LRSI K E + K+ + Sbjct: 197 DKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPP 256 Query: 450 FLMEMLE 456 + EMLE Sbjct: 257 LIQEMLE 263 >1XAP-A nrPDB Length = 267 Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 62/187 (33%), Positives = 103/187 (55%), Gaps = 1/187 (0%) Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 + A K + +VE+AKR+P F+ L + DQ+ LL+A ++LI R +D + + G Sbjct: 76 ELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG 135 Query: 330 LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 L ++R H+AG G + D V T +++ ++MD TE G L AI L D + L P +V Sbjct: 136 LTLNRTQMHNAGFGPLTDLVFT-FANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKV 194 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 + L+E + +L+ Y + + P +P F K+L+++ LRSI K E + K+ + Sbjct: 195 DKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPP 254 Query: 450 FLMEMLE 456 + EMLE Sbjct: 255 LIQEMLE 261 >2ENV-A nrPDB Length = 88 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 41/72 (56%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD++SG HYGV++CEGCKGFF+RT+R L Y + + C I K+ RN+CQYCR+QK Sbjct: 10 CRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYE-KCERSCKIQKKNRNKCQYCRFQK 68 Query: 195 CLAMGMKREAVQ 206 CLA+GM A++ Sbjct: 69 CLALGMSHNAIR 80 >1A6Y-A nrPDB Length = 94 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 43/85 (50%), Positives = 64/85 (75%), Gaps = 3/85 (3%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYT-CRDNKDCLIDKRQRNRCQYCRY 192 +C +CGD +SG HYGV +CEGCKGFF+R++++++ Y C N++C I + RNRCQ CR+ Sbjct: 9 LCKVCGDVASGFHYGVLACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 68 Query: 193 QKCLAMGMKREAVQEER--QRGKDR 215 +KCL++GM R+AV+ R +R K R Sbjct: 69 KKCLSVGMSRDAVRFGRIPKREKQR 93 >1LO1-A nrPDB Length = 98 Score = 100 bits (250), Expect = 1e-21, Method: Composition-based stats. Identities = 43/95 (45%), Positives = 64/95 (67%), Gaps = 1/95 (1%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 K +C +CGD +SG HYGV SCE CK FFKRT++ ++ Y+C +C I KR+R CQ CR Sbjct: 4 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 63 Query: 192 YQKCLAMGMKREAVQEERQR-GKDRNENEVESTSS 225 + K L +GM +E V+ +R R G+ + + ++S +S Sbjct: 64 FMKALKVGMLKEGVRLDRVRGGRQKYKRRLDSENS 98 >3A9E-B nrPDB Length = 269 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 58/187 (31%), Positives = 99/187 (52%), Gaps = 1/187 (0%) Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 + + K + VE+AK++P F+ L + DQ+ LL+A ++LI R +D + + G Sbjct: 78 ELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG 137 Query: 330 LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 L ++R H+AG G + D V +++ ++MD E G L AI L D + L P V Sbjct: 138 LTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 196 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 + L+E + +L+ Y + + P +P F K+L+++ LRSI K E + K+ + Sbjct: 197 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 256 Query: 450 FLMEMLE 456 + EMLE Sbjct: 257 LIQEMLE 263 >5K13-A nrPDB Length = 246 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 58/187 (31%), Positives = 99/187 (52%), Gaps = 1/187 (0%) Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 + + K + VE+AK++P F+ L + DQ+ LL+A ++LI R +D + + G Sbjct: 50 ELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG 109 Query: 330 LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 L ++R H+AG G + D V +++ ++MD E G L AI L D + L P V Sbjct: 110 LTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 168 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 + L+E + +L+ Y + + P +P F K+L+++ LRSI K E + K+ + Sbjct: 169 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 228 Query: 450 FLMEMLE 456 + EMLE Sbjct: 229 LIQEMLE 235 >4OLN-A nrPDB Length = 82 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 39/79 (49%), Positives = 55/79 (69%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 K +C +CGD +SG HYGV+SCEGCK FFKR+++ + Y C +C IDK +R CQ CR Sbjct: 4 KRLCQVCGDHASGFHYGVWSCEGCKAFFKRSIQGHVDYVCPATNNCTIDKHRRKSCQACR 63 Query: 192 YQKCLAMGMKREAVQEERQ 210 +KCL +GM + ++ER+ Sbjct: 64 LRKCLEVGMTKGGQRKERR 82 >3K6P-A nrPDB Length = 248 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 66/208 (31%), Positives = 110/208 (52%), Gaps = 8/208 (3%) Query: 257 NPSSPND---PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASF 313 +P+ P+ V +C D+++ + WAK IP FS L L DQ+ +L++ W E+L+ Sbjct: 39 DPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGV 98 Query: 314 SHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAI 373 + RS+ ++D + A L + A +AG+G + L +LV +++ +++++ E L+A+ Sbjct: 99 AQRSLPLQDELAFAEDLVLDEEGARAAGLGEL-GAALLQLVRRLQALRLEREEYVLLKAL 157 Query: 374 VLFNPDSKGLSNPAEVEALREKVYASLEAY----CKHKYPEQPGRFAKLLLRLPALRSIG 429 L N DS + + VE LRE ++ +L Y + R +LLL LP LR Sbjct: 158 ALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTA 217 Query: 430 LKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 K L H + KL G P+ +EMLEA Sbjct: 218 GKVLAHFYGVKLEGKVPMHKLFLEMLEA 245 >2NLL-B nrPDB Length = 103 Score = 99.4 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 38/84 (45%), Positives = 61/84 (72%), Gaps = 2/84 (2%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL--TYTCRDNKDCLIDKRQRNRCQYCR 191 +C +CGD+++G HY +CEGCKGFF+RT++K+L +Y+C+ C+IDK RN+CQ CR Sbjct: 3 LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECR 62 Query: 192 YQKCLAMGMKREAVQEERQRGKDR 215 ++KC+ +GM + V ++ +R R Sbjct: 63 FKKCIYVGMATDLVLDDSKRLAKR 86 >5M24-A nrPDB Length = 250 Score = 99.4 bits (246), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 62/190 (32%), Positives = 100/190 (52%), Gaps = 1/190 (0%) Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 + A K + +VE+AKR+P F+ L + DQ+ LL+A ++L+ R +D + + G Sbjct: 59 ELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDG 118 Query: 330 LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 L ++R H+AG G + D V ++ ++MD TE G L AI L D L P +V Sbjct: 119 LTLNRTQMHNAGFGPLTDLVFA-FAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKV 177 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 + L+E + +L Y + + PEQP F ++L+++ LR I K E K+ P+ Sbjct: 178 DKLQEPLLEALRLYARRRRPEQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPP 237 Query: 450 FLMEMLEAPH 459 + EMLE P Sbjct: 238 LIREMLENPE 247 >2XHS-A nrPDB Length = 245 Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 58/192 (30%), Positives = 98/192 (51%), Gaps = 3/192 (1%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI--AVKDGIL 325 +C+ D+ LF+ V+WA+ F +L +DDQ+ LL+ W+++L+ H I + D Sbjct: 51 MCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQ 110 Query: 326 LATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSN 385 L G + S GV + D EL +K++D++ D + C++ ++L NP +G+ N Sbjct: 111 LNNGQVFNLMSLGLLGVPQLGD-YFNELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIVN 169 Query: 386 PAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT 445 V + V A+L Y YP +F L+ LP + ++ ++ +HL+ G Sbjct: 170 RKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHCAGSA 229 Query: 446 PIDTFLMEMLEA 457 P T LMEML A Sbjct: 230 PTQTLLMEMLHA 241 >4UMM-E nrPDB Length = 87 Score = 97.4 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 40/84 (47%), Positives = 54/84 (64%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + +C +CGDR+SG HY +CEGCKGFF+R+V K+ Y C+ C +D R +CQ CR Sbjct: 4 EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECR 63 Query: 192 YQKCLAMGMKREAVQEERQRGKDR 215 +KCLA+GM+ E V E Q R Sbjct: 64 LKKCLAVGMRPECVVPENQCAMKR 87 >4QJR-A nrPDB Length = 245 Score = 95.5 bits (236), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 70/205 (34%), Positives = 114/205 (55%), Gaps = 6/205 (2%) Query: 259 SSPNDPVTN--ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 S P+ P +C+ AD+ ++V+WA+R F EL + DQ+ LL+ W+ELL+ +R Sbjct: 38 SRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYR 97 Query: 317 SIAV-KDG-ILLATGLHVHRNSAHSAGVGAIFDRVL--TELVSKMRDMQMDKTELGCLRA 372 + K+G ILL TG V + + + VL ELV ++ +Q+D+ E CL+ Sbjct: 98 QVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKF 157 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I+LF+ D K L+N V+ +EK A+L Y YP +F +LLL L +R++ ++ Sbjct: 158 IILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDKFQQLLLCLVEVRALSMQA 217 Query: 433 LEHLFFFKLIGDTPIDTFLMEMLEA 457 E+L+ L + P + L+EML+A Sbjct: 218 KEYLYHKHLGNEMPRNNLLIEMLQA 242 >6IAR-A nrPDB Length = 237 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 12/212 (5%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 +P+ P + + AD++L ++ WAKR+P F +L L DQV LL + W E+L+ R Sbjct: 26 DPTRPFSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWR 85 Query: 317 SIAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVL 375 S+ +L A L + RN S G+ IFD +L S+ R M + E CL++I+L Sbjct: 86 SMEHPGKLLFAPNLLLDRNQGKSVEGMVEIFDMLLAT-SSRFRMMNLQGEEFVCLKSIIL 144 Query: 376 -------FNPDSKGLSNPAEVEALREKV---YASLEAYCKHKYPEQPGRFAKLLLRLPAL 425 F+ K L + + +K+ L A +Q R A+LLL L + Sbjct: 145 LNSGVYTFSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI 204 Query: 426 RSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 R + K +EHL+ K P L+EML+A Sbjct: 205 RHMSNKGMEHLYSMKCKNVVPSYDLLLEMLDA 236 >1KB2-A nrPDB Length = 110 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 40/92 (43%), Positives = 59/92 (64%), Gaps = 6/92 (6%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 IC +CGDR++G H+ +CEGCKGFF+R++++ +TC N DC I K R CQ CR + Sbjct: 8 ICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLK 67 Query: 194 KCLAMGMKREAV--QEERQRGKD----RNENE 219 +C+ +GM +E + EE QR ++ R E E Sbjct: 68 RCVDIGMMKEFILTDEEVQRKREMILKRKEEE 99 >2OCF-A nrPDB Length = 298 Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 66/212 (31%), Positives = 100/212 (47%), Gaps = 13/212 (6%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S + + AD++L ++ WAKR+P F +L L DQV LL W E+L+ RS Sbjct: 39 PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRS 98 Query: 318 IAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLF 376 + +L A L + RN G+ IFD +L S+ R M + E CL++I+L Sbjct: 99 MEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLAT-SSRFRMMNLQGEEFVCLKSIILL 157 Query: 377 NPDS--------KGLSNPAEVEALREKVYAS---LEAYCKHKYPEQPGRFAKLLLRLPAL 425 N K L + + +K+ + L A +Q R A+LLL L + Sbjct: 158 NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI 217 Query: 426 RSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 R + K +EHL+ K P+ L+EML+A Sbjct: 218 RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDA 249 >4PXM-A nrPDB Length = 271 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 66/212 (31%), Positives = 99/212 (46%), Gaps = 13/212 (6%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S + + AD++L ++ WAKR+P F +L L DQV LL W E+L+ RS Sbjct: 53 PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRS 112 Query: 318 IAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLF 376 + +L A L + RN G+ IFD +L S+ R M + E CL++I+L Sbjct: 113 MEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLAT-SSRFRMMNLQGEEFVCLKSIILL 171 Query: 377 NPDS--------KGLSNPAEVEALREKV---YASLEAYCKHKYPEQPGRFAKLLLRLPAL 425 N K L + + +K+ L A +Q R A+LLL L + Sbjct: 172 NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI 231 Query: 426 RSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 R + K +EHL+ K P+ L+EML+A Sbjct: 232 RHMSNKGMEHLYSMKCKNVVPLYGLLLEMLDA 263 >4AA6-A nrPDB Length = 71 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 35/68 (51%), Positives = 45/68 (66%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 CA+C D +SG HYGV+SCEGCK FFKR+++ Y C C IDK +R CQ CR +K Sbjct: 4 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 63 Query: 195 CLAMGMKR 202 C +GM + Sbjct: 64 CYEVGMMK 71 >1R0O-B nrPDB Length = 109 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 41/89 (46%), Positives = 56/89 (62%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192 +C +CGDR+SG HY +CEGCKGFF+R+V K Y C+ + C +D R +CQ CR Sbjct: 7 ELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRL 66 Query: 193 QKCLAMGMKREAVQEERQRGKDRNENEVE 221 +KCLA+GM+ E V E Q R E + + Sbjct: 67 KKCLAVGMRPECVVPENQCAMKRREKKAQ 95 >1LAT-A nrPDB Length = 82 Score = 89.0 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 37/76 (48%), Positives = 48/76 (63%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D +SG HYGV +CEGCK FFKR V Y C+ C+IDK +R C CRY+K Sbjct: 7 CLVCSDEASGCHYGVLTCEGCKAFFKRAVEGQHNYLCKYEGKCIIDKIRRKNCPACRYRK 66 Query: 195 CLAMGMKREAVQEERQ 210 CL GM EA + +++ Sbjct: 67 CLQAGMNLEARKTKKK 82 >2V0V-A nrPDB Length = 194 Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 55/163 (33%), Positives = 83/163 (50%), Gaps = 1/163 (0%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AKRIP F +L DQV LL+AG E+L+ F+ A + + + H Sbjct: 31 VVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLGSKKYSVDDLH 90 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 S G G + + + E K+ +Q+ E+ A+VL + D G+ N VEAL+E + Sbjct: 91 SMGAGDLLNSMF-EFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIR 149 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 +L +P + F KLLL+LP LRS+ E L FK+ Sbjct: 150 ALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKV 192 >6EU9-A nrPDB Length = 241 Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 55/195 (28%), Positives = 99/195 (50%), Gaps = 13/195 (6%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 + + + K + +V++ K++P F++L +DQ+ LL+A E++I + R +D + + Sbjct: 50 VSELSTKAIANVVDFGKQVPVFTQLSTNDQITLLKAACLEIIILRLASRYDDKEDTMSFS 109 Query: 328 TGLHVHRNSAHSAGVGAI------FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSK 381 GL + + G G + F R L EL +D E L I L + D Sbjct: 110 NGLTLTQQQLEVGGFGTLTPTIFKFARSLVEL-------SVDTAEYAMLSLICLISGDRS 162 Query: 382 GLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 GL +P +VE +E + +L+ Y + + P+ P FAKLLL+L LRS+ +K E + ++ Sbjct: 163 GLEHPEKVEQKQEPILETLKHYVRKRRPDSPHSFAKLLLKLTDLRSLSVKGAERVLQLRM 222 Query: 442 IGDTPIDTFLMEMLE 456 + ++EML+ Sbjct: 223 EMPGELPPLILEMLD 237 >2J7X-A nrPDB Length = 255 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 75/244 (30%), Positives = 119/244 (48%), Gaps = 19/244 (7%) Query: 232 VERILEAELAVEPKTETYVEANM-GLNPSSPNDPVT------NICQAADKQLFTLVEWAK 284 V+ +L + L+ E T +EA + S P+ P T ++ + ADK+L ++ WAK Sbjct: 1 VKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAK 60 Query: 285 RIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVG 343 +IP F EL L DQV LL + W E+L+ RSI ++ A L + R+ G+ Sbjct: 61 KIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGIL 120 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP-AEVEALREKVY----- 397 IFD +L S+ R++++ E C++A++L N L++ E E+ R+ + Sbjct: 121 EIFDMLLAT-TSRFRELKLQHKEYLCVKAMILLNSSMYPLASANQEAESSRKLTHLLNAV 179 Query: 398 --ASLEAYCKHKYP--EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLME 453 A + K +Q R A LL+ L +R I K +EHL K P+ L+E Sbjct: 180 TDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLE 239 Query: 454 MLEA 457 ML A Sbjct: 240 MLNA 243 >5CBX-A nrPDB Length = 105 Score = 87.4 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 37/76 (48%), Positives = 47/76 (61%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 IC +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C CR++ Sbjct: 30 ICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFR 89 Query: 194 KCLAMGMKREAVQEER 209 KCL GM EA + ++ Sbjct: 90 KCLQAGMNLEARKTKK 105 >1GDC-A nrPDB Length = 72 Score = 86.7 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 36/71 (50%), Positives = 43/71 (60%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY+ Sbjct: 1 LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYR 60 Query: 194 KCLAMGMKREA 204 KCL GM EA Sbjct: 61 KCLQAGMNLEA 71 >6CFN-A nrPDB Length = 90 Score = 86.7 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 36/77 (46%), Positives = 47/77 (61%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY+ Sbjct: 4 LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYR 63 Query: 194 KCLAMGMKREAVQEERQ 210 KCL GM EA + +++ Sbjct: 64 KCLQAGMNLEARKTKKK 80 >5EMP-A nrPDB Length = 94 Score = 85.1 bits (209), Expect = 6e-17, Method: Composition-based stats. Identities = 36/77 (46%), Positives = 47/77 (61%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY+ Sbjct: 14 LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYR 73 Query: 194 KCLAMGMKREAVQEERQ 210 KCL GM EA + +++ Sbjct: 74 KCLQAGMNLEARKTKKK 90 >4TNT-A nrPDB Length = 103 Score = 85.1 bits (209), Expect = 6e-17, Method: Composition-based stats. Identities = 37/73 (50%), Positives = 43/73 (58%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 +S IC +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 28 SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 87 Query: 188 QYCRYQKCLAMGM 200 CR QKCL GM Sbjct: 88 PACRLQKCLQAGM 100 >1GLU-A nrPDB Length = 81 Score = 84.3 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 36/75 (48%), Positives = 45/75 (60%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY+K Sbjct: 7 CLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRK 66 Query: 195 CLAMGMKREAVQEER 209 CL GM EA + ++ Sbjct: 67 CLQAGMNLEARKTKK 81 >2YLY-A nrPDB Length = 240 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/215 (30%), Positives = 103/215 (47%), Gaps = 17/215 (7%) Query: 259 SSPNDPVT------NICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 S P+ P T ++ + ADK+L ++ WAK+IP F EL L DQV LL + W E+L+ Sbjct: 24 SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMG 83 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLR 371 RSI ++ A L + R+ G+ IFD +L S+ R++++ E C++ Sbjct: 84 LMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLAT-TSRFRELKLQHKEYLCVK 142 Query: 372 AIVLFNPDSKGLSNPAEVEALREKVY-------ASLEAYCKHKYP--EQPGRFAKLLLRL 422 A++L N L + ++ R+ + A + K +Q R A LL+ L Sbjct: 143 AMILLNSSMYPLVTATQDDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLL 202 Query: 423 PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +R K +EHL K P+ L+EML A Sbjct: 203 SHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNA 237 >5CC0-A nrPDB Length = 85 Score = 84.0 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 38/82 (46%), Positives = 48/82 (58%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 AS + +C ICGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 3 ASPPQKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 62 Query: 188 QYCRYQKCLAMGMKREAVQEER 209 CR +KCL GM A + ++ Sbjct: 63 PACRLRKCLQAGMTLGARKSKK 84 >5CBZ-A nrPDB Length = 105 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 37/82 (45%), Positives = 47/82 (57%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 AS +C +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 24 ASPPSKVCLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 83 Query: 188 QYCRYQKCLAMGMKREAVQEER 209 CR +KCL GM A + ++ Sbjct: 84 PACRLRKCLQAGMNLGARKSKK 105 >2H79-A nrPDB Length = 269 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 47/151 (31%), Positives = 81/151 (53%), Gaps = 1/151 (0%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +V++AK++P FSELP +DQ+ILL+ E++ + R D + L+ + V R Sbjct: 88 VVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLK 147 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 + G+G + D + EL + +D TE+ L+A++L + D GL ++E +E Sbjct: 148 NGGLGVVSDAIF-ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLL 206 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 + E Y H+ P + KLL+++ LR IG Sbjct: 207 AFEHYVNHRKHNIPHFWPKLLMKVTDLRMIG 237 >1OVL-B nrPDB Length = 271 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 51/180 (28%), Positives = 92/180 (51%), Gaps = 9/180 (5%) Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG 341 WA++IP F++LP DQ +L + + EL + ++RS V+ ++ G+ +HR G Sbjct: 93 WAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRG 151 Query: 342 VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLE 401 G D ++ E S +++M +D + C+ A+ + + GL P VE L+ K+ L+ Sbjct: 152 FGEWIDSIV-EFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLK 209 Query: 402 AYCKHKYP--EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEML 455 + +P +KLL +LP LR++ + L+ +F+ KL P ID ++ L Sbjct: 210 DHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 269 >2C7A-A nrPDB Length = 78 Score = 80.5 bits (197), Expect = 1e-15, Method: Composition-based stats. Identities = 33/69 (47%), Positives = 41/69 (59%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + IC ICGD +SG HYGV +C CK FFKR + Y C DC++DK +R C CR Sbjct: 2 QKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACR 61 Query: 192 YQKCLAMGM 200 +KC GM Sbjct: 62 LRKCCQAGM 70 >1Z5X-E nrPDB Length = 310 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 60/180 (33%), Positives = 96/180 (53%), Gaps = 4/180 (2%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE++KR+P F +L +DQ+ LL+A +E+++ + R A D IL AT R S Sbjct: 132 IVEFSKRLPGFDKLIREDQIALLKACSSEVMMFRMARRYDAETDSILFATNQPYTRESYT 191 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 AG+G + +L M M++D E L AIV+F+ + LS +VE ++E Sbjct: 192 VAGMGDTVEDLL-RFCRHMCAMKVDNAEYALLTAIVIFS-ERPSLSEGWKVEKIQEIYIE 249 Query: 399 SLEAYCKHKY-PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +L+AY +++ P FAKLL L LR++G E F KL + + +FL E+ + Sbjct: 250 ALKAYVENRRKPYATTIFAKLLSVLTELRTLGNMNSETCFSLKL-KNRKVPSFLEEIWDV 308 >5KYJ-A nrPDB Length = 287 Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 112/227 (49%), Gaps = 13/227 (5%) Query: 225 SANEDMPVERILEAEL-------AVEPKTETYVEANMGLNPSS---PNDPVTNICQAADK 274 +A +++ +++++ A+L + +PK + +G +P+S + + A Sbjct: 28 TAAQELMIQQLVAAQLQCNKRSFSDQPKVTPW---PLGADPASGSASQQRFAHFTELAII 84 Query: 275 QLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHR 334 + +V++AK++P F +L +DQ+ LL+A E+++ + R + I + Sbjct: 85 SVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSK 144 Query: 335 NSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALRE 394 + H AG+ F + E MR + +D E L AI +F+ D + P VEAL++ Sbjct: 145 DDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQ 204 Query: 395 KVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 +L +Y + K P+ RF ++L++L +LR++ E +F +L Sbjct: 205 PYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRL 251 >3N00-A nrPDB Length = 245 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 11/168 (6%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILL---ATGLHVHRN 335 +VE+AK IP F +L DQV LL+AG E+L+ F+ VKD ++ T + Sbjct: 81 VVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASL-FNVKDQTVMFLSRTTYSLQEL 139 Query: 336 SAHSAG--VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR 393 A G + A+FD K+ + + + ELG A+VL + D G+ N A VE L+ Sbjct: 140 GAMGMGDLLSAMFD-----FSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 194 Query: 394 EKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 E + +L A P + RF KLLL+LP LR++ E L F++ Sbjct: 195 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRV 242 >4XAI-A nrPDB Length = 573 Score = 79.0 bits (193), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 16/200 (8%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 IC++A + +F V+W + IP F+ LPL DQ++LL W +L + + + + + D +L Sbjct: 376 ICESAAQLIFMNVQWVRSIPAFTCLPLSDQLLLLEESWLDLFVLG-AAQFLPLMDFSVLV 434 Query: 328 TGLHVHRNSAH--SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLF-----NPDS 380 V + H A + + D E + K+ Q+D E CLRAIVLF P S Sbjct: 435 EACGVLQQEPHRRDAFLKEVAD--FQETLKKISQFQLDAHEFACLRAIVLFKTSFEKPSS 492 Query: 381 -----KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPA-LRSIGLKCLE 434 K + A++ +++ L + YP+QP RF K+LL + + R+I + +E Sbjct: 493 SSNQEKTTTESAKISVIQDDAQMRLNKHVTTTYPKQPLRFGKILLLVSSTFRTISGRTIE 552 Query: 435 HLFFFKLIGDTPIDTFLMEM 454 LFF K+I DTPI + M Sbjct: 553 DLFFKKVIRDTPIVAIISNM 572 >2NXX-E nrPDB Length = 248 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 3/164 (1%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AKR+P F +L +DQ+ LL+A +E+++ + R D IL R+S + Sbjct: 68 IVEFAKRLPGFDKLLREDQIALLKACSSEVMMFRMARRYDVQTDSILFVNNQPYSRDSYN 127 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 AG+G + +L M M++D E L AIV+F+ + L +VE ++E Sbjct: 128 LAGMGETIEDLL-HFCRTMYSMRVDNAEYALLTAIVIFS-ERPALIEGWKVEKIQEIYLE 185 Query: 399 SLEAYCKHKYPEQPGR-FAKLLLRLPALRSIGLKCLEHLFFFKL 441 +L AY ++ +PG FAKLL L LR++G + E F KL Sbjct: 186 ALRAYVDNRRKPKPGTIFAKLLSVLTELRTLGNQNSEMCFSLKL 229 >3V3Q-A nrPDB Length = 257 Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 56/181 (30%), Positives = 92/181 (50%), Gaps = 9/181 (4%) Query: 281 EWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA 340 +WA++IP F+EL DQ +LL + + EL I ++RS + ++ +GL +HR + Sbjct: 70 KWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-AR 128 Query: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASL 400 G G D +L + + +D CL A+VL D GL P VE L+ ++ + L Sbjct: 129 GFGDWIDSILA-FSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCL 186 Query: 401 EAYCKHKYPE-QPGR-FAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEM 454 + + E QP ++LL +LP LR++ + L+ +F+ KL P ID M+ Sbjct: 187 KEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDT 246 Query: 455 L 455 L Sbjct: 247 L 247 >1R4I-A nrPDB Length = 105 Score = 76.6 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 40/96 (41%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C CR +K Sbjct: 10 CLICGDEASGAHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 69 Query: 195 CLAMGMKREA-VQEERQRGKDRNENEVESTSSANED 229 C GM A ++ K + E E S S ED Sbjct: 70 CYEAGMTLGARKLKKLGNLKLQEEGENSSAGSPTED 105 >3UVV-A nrPDB Length = 265 Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 44/151 (29%), Positives = 81/151 (53%), Gaps = 1/151 (0%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +V++AK++P FSELP +DQ+ILL+ E++ + R + + L+ + V R Sbjct: 84 VVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLK 143 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 + G+G + D + +L + +D TE+ L+A++L + D GL ++E +E Sbjct: 144 NGGLGVVSDAIF-DLGKSLSAFNLDDTEVALLQAVLLMSSDRTGLICVDKIEKCQETYLL 202 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 + E Y ++ P + KLL+++ LR IG Sbjct: 203 AFEHYINYRKHNIPHFWPKLLMKVTDLRMIG 233 >1YJE-A nrPDB Length = 264 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 53/181 (29%), Positives = 90/181 (49%), Gaps = 9/181 (4%) Query: 281 EWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA 340 +WA++IP F EL DQ +LL + + EL I ++RS + ++ +GL +HR + Sbjct: 85 KWAEKIPGFIELSPGDQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-AR 143 Query: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASL 400 G G D +L + + +D CL A+VL D GL +P VE L+ ++ + L Sbjct: 144 GFGDWIDNILA-FSRSLHSLGVDVPAFACLSALVLIT-DRHGLQDPRRVEELQNRIASCL 201 Query: 401 EAYCKHKY--PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEM 454 + + P+ ++LL +LP LR++ + L+ +F KL P +D M+ Sbjct: 202 KEHMAAVAGDPQPASCLSRLLGKLPELRTLCTQGLQRIFCLKLEDLVPPPPIVDKIFMDT 261 Query: 455 L 455 L Sbjct: 262 L 262 >4OZT-E nrPDB Length = 238 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 55/164 (33%), Positives = 85/164 (51%), Gaps = 3/164 (1%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AKR+P F +L +DQ+ LL+A +E+++ + R D IL A R+S Sbjct: 62 IVEFAKRLPGFDKLLREDQIALLKACSSEVMMLRMARRYDVGSDSILFANNQPYTRDSYS 121 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 AG+G D +L +M M++D E L AIV+F+ + L +VE ++E Sbjct: 122 LAGMGETVDDLL-RFCRQMYGMKVDNAEYALLTAIVIFS-ERPSLIEGWKVEKIQEIYLE 179 Query: 399 SLEAYCKHKYPEQPGR-FAKLLLRLPALRSIGLKCLEHLFFFKL 441 +L+ Y ++ G FAKLL L LR++G E F KL Sbjct: 180 ALKVYVDNRRKPASGTIFAKLLSVLTELRTLGNLNSEMCFSLKL 223 >5LSG-A nrPDB Length = 304 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 54/185 (29%), Positives = 93/185 (50%), Gaps = 9/185 (4%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGL-HVHRNSA 337 + E+AK IP F L L+DQV LL+ G +E++ + S+ KDG+L++ G + R Sbjct: 123 ITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLA--SLMNKDGVLISEGQGFMTREFL 180 Query: 338 HSAG--VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK 395 S G + E K +++D ++L A+++ + D GL N +E +++ Sbjct: 181 KSLRKPFGDFMEPKF-EFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDN 239 Query: 396 VYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 + +LE K +PE FAKLL ++ LR I EH+ ++I T D L +L Sbjct: 240 LLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEHVQLLQVIKKTETDMSLHPLL 296 Query: 456 EAPHQ 460 + ++ Sbjct: 297 QEIYK 301 >3FAL-B nrPDB Length = 266 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 80/163 (49%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +V++AK++P F +L +DQ+ LL+ E+++ S R + I +R Sbjct: 87 IVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFA 146 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 AG+ F + E M ++Q++ E L AI +F+ D + + +VE L+ Sbjct: 147 KAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVE 206 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 +L AY +P P F ++L++L +LR++ E +F +L Sbjct: 207 ALHAYVSINHPHDPLMFPRMLMKLVSLRTLSSVHSEQVFALRL 249 >2XYJ-A nrPDB Length = 288 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 59/193 (30%), Positives = 92/193 (47%), Gaps = 25/193 (12%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 L E+AK IP FS L L+DQV LL+ G +E + A + SI KDG+L+A G Sbjct: 107 LTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLA--SIVNKDGLLVANG--------- 155 Query: 339 SAGVGAIFDRVLT-----------ELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA 387 S V F R L E K +++D ++L A ++ D GL N Sbjct: 156 SGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVP 215 Query: 388 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI 447 VEA+++ + +LE + + +P+ F KLL ++ LR + EH + I T Sbjct: 216 RVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQL---VTEHAQMMQRIKKTET 272 Query: 448 DTFLMEMLEAPHQ 460 +T L +L+ ++ Sbjct: 273 ETSLHPLLQEIYK 285 >1R20-D nrPDB Length = 265 Score = 72.0 bits (175), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 5/156 (3%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AK +P FS++ DQ+ LL+A +E+++ + R A D +L A R++ Sbjct: 83 IVEFAKGLPGFSKISQSDQITLLKACSSEVMMLRVARRYDAATDSVLFANNQAYTRDNYR 142 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 AG+ + + +L M M MD L AIV+F+ D GL P+ VE ++ Sbjct: 143 KAGMAYVIEDLL-HFCRCMYSMMMDNVHYALLTAIVIFS-DRPGLEQPSLVEEIQRYYLN 200 Query: 399 SLEAYCKHKYPEQPGR---FAKLLLRLPALRSIGLK 431 +L Y ++ P F K+L L +R++G++ Sbjct: 201 TLRVYILNQNSASPRSAVIFGKILGILTEIRTLGMQ 236 >4N1Y-A nrPDB Length = 240 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 103/197 (52%), Gaps = 8/197 (4%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV-KDG 323 + ++ + A+++L L+ WAK +P +++L L DQV L+ W ELL+ + + RSI Sbjct: 38 LNSLVKLAERELVHLINWAKNVPGYTDLSLSDQVHLIECCWMELLLLNCAFRSIEHGGKS 97 Query: 324 ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL 383 + A L + R+S + + IF++V + +M + K EL L+A+VL N + + L Sbjct: 98 LAFAPDLVLDRSSWSTVEMTEIFEQV-AAVSEQMMQNHLHKDELLLLQAMVLVNAEVRRL 156 Query: 384 SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 443 ++ ++ +++ + ++ + +P+ +LL L +R G + + FF+ + Sbjct: 157 ASYNQIFNMQQSLLDAIVDTAQKYHPDNVRHVPAVLLLLTHIRQAGERGIA---FFQRLK 213 Query: 444 DTPIDTF---LMEMLEA 457 + TF L EML+A Sbjct: 214 SEGVVTFCDLLKEMLDA 230 >3D57-A nrPDB Length = 266 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 77/151 (50%), Gaps = 1/151 (0%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +V++AK++P F ELP +DQ+ILL+ E++ + R + + L + V R Sbjct: 89 VVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLK 148 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 + G+G + D + L + +D TE+ L+A++L + D GL+ +E ++ Sbjct: 149 NGGLGVVSDAIF-RLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLL 207 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 + E Y ++ + KLL+++ LR IG Sbjct: 208 AFEHYINYRKHHVTHFWPKLLMKVTDLRMIG 238 >1PDU-A nrPDB Length = 244 Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 92/184 (50%), Gaps = 5/184 (2%) Query: 260 SPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA 319 S D V Q + + ++A++IP + +L +DQ +L ++ EL + ++R+ Sbjct: 44 SEADKVQQFYQLLTSSVDVIKQFAEKIPGYFDLLPEDQELLFQSASLELFVLRLAYRARI 103 Query: 320 VKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPD 379 ++ G +HR + G + ++ E + ++++D + CL A+ L + Sbjct: 104 DDTKLIFCNGTVLHRTQCLRS-FGEWLNDIM-EFSRSLHNLEIDISAFACLCALTLIT-E 160 Query: 380 SKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGR--FAKLLLRLPALRSIGLKCLEHLF 437 GL P +VE L+ K+ SL + + Q + F++LL +LP LRS+ ++ L+ +F Sbjct: 161 RHGLREPKKVEQLQMKIIGSLRDHVTYNAEAQKKQHYFSRLLGKLPELRSLSVQGLQRIF 220 Query: 438 FFKL 441 + KL Sbjct: 221 YLKL 224 >4NUF-A nrPDB Length = 580 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 54/199 (27%), Positives = 85/199 (42%), Gaps = 12/199 (6%) Query: 269 CQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA--VKDGILL 326 C+ A L V + + +P F LP DDQ LL W L + + ++ V + + Sbjct: 379 CREALDVLAKTVAFLRNLPSFCHLPHDDQRRLLECCWGPLFLLGLAQDAVTFEVAEAPVP 438 Query: 327 ATGLHVHRNSAHSAGVGAI-FDR---------VLTELVSKMRDMQMDKTELGCLRAIVLF 376 + + A S GA DR L + +++ E L+ +LF Sbjct: 439 SILKKILTTRASSGTQGAQPSDRPQPSLAAVQWLQRCLESFWSLELGPKEYAYLKGTILF 498 Query: 377 NPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHL 436 NPD GL + L+++ + +L + YP GR A++LL LR+I L L Sbjct: 499 NPDVPGLRASCHIAHLQQEAHWALCEVLEPWYPASQGRLARILLMASTLRNIPGTLLVDL 558 Query: 437 FFFKLIGDTPIDTFLMEML 455 FF ++GD I L +ML Sbjct: 559 FFRPIMGDVDITELLEDML 577 >3F5C-B nrPDB Length = 268 Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 55/213 (25%), Positives = 86/213 (40%), Gaps = 25/213 (11%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 +C+AA L + + K +P F LPLD Q++L+R+ W LL+ + + + + Sbjct: 52 VCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPE 111 Query: 328 TG-----LHVHRNSAH----------------SAGVGAIFDRVLTELVS----KMRDMQM 362 T L R SA G + + + K + + Sbjct: 112 TNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNI 171 Query: 363 DKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRL 422 D E L+ VLFNPD GL +E L+ + L + + E R A+L L Sbjct: 172 DTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSAL 231 Query: 423 PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 LR I + LFF +IG +D ++EML Sbjct: 232 FLLRFINSDVVTELFFRPIIGAVSMDDMMLEML 264 >5Y44-A nrPDB Length = 227 Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 44/162 (27%), Positives = 77/162 (47%), Gaps = 4/162 (2%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 + + A + LVE+ K++P F L +DQ+ LL+ E + RS + + L + Sbjct: 44 LTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFL----RSAEIFNKKLPS 99 Query: 328 TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA 387 + ++G+ + + + +++M + E L AIV+ +PD + + + Sbjct: 100 GHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDRE 159 Query: 388 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 VE L+E + L+ CK PE P FAKLL RL LR+ Sbjct: 160 AVEKLQEPLLDVLQKLCKIHQPENPQHFAKLLGRLTELRTFN 201 >3ET1-A nrPDB Length = 291 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 56/211 (26%), Positives = 98/211 (46%), Gaps = 12/211 (5%) Query: 255 GLNPSSPNDPVTNICQAADKQLFT-LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASF 313 G+ + + CQ + T L E+AK IP F+ L L+DQV LL+ G E + A Sbjct: 85 GIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAML 144 Query: 314 SHRSIAVKDGILLATGL-HVHRNSAHSAGVGAIFDRVLT---ELVSKMRDMQMDKTELGC 369 S S+ KDG+L+A G + R S + F ++ + K +++D +++ Sbjct: 145 S--SVMNKDGMLVAYGNGFITREFLKS--LRKPFCDIMEPKFDFAMKFNALELDDSDISL 200 Query: 370 LRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 A ++ D GL N +E ++E + L + + +P+ F KLL ++ LR + Sbjct: 201 FVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQL- 259 Query: 430 LKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQ 460 EH ++I T D L +L+ ++ Sbjct: 260 --VTEHAQLVQIIKKTESDAALHPLLQEIYR 288 >1OT7-A nrPDB Length = 229 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 45/162 (27%), Positives = 75/162 (46%), Gaps = 4/162 (2%) Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 + + A + LVE+ KR+P F L +DQ+ LL+ E + RS + + L A Sbjct: 45 LTEMATSHVQILVEFTKRLPGFQTLDHEDQIALLKGSAVEAMFL----RSAEIFNKKLPA 100 Query: 328 TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA 387 + +G+ + + + +++M + E L AIV+ +PD + + + Sbjct: 101 GHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDRE 160 Query: 388 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 VE L+E + L+ CK PE P FA LL RL LR+ Sbjct: 161 AVEKLQEPLLDVLQKLCKIYQPENPQHFACLLGRLTELRTFN 202 >1XVP-B nrPDB Length = 246 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 78/167 (46%), Gaps = 3/167 (1%) Query: 265 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 VT+ + ++++ K +P F LP++DQ+ LL+ E+ + + ++ Sbjct: 56 VTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLN-TTFCLQTQN 114 Query: 325 LLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLS 384 L L G F +L +R +Q+ + E L A+ LF+PD G++ Sbjct: 115 FLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVT 174 Query: 385 NPAEVEALREKVYASLEAYCK--HKYPEQPGRFAKLLLRLPALRSIG 429 E++ L+E++ +L++Y K + P +AKLL L LRSI Sbjct: 175 QRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 221 >1N4H-A nrPDB Length = 259 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 76/153 (49%), Gaps = 9/153 (5%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLAT---GLHVHRN 335 +VE+AKRI F EL +DQ++LL++G E+++ + + +L G+ + + Sbjct: 73 VVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKA 132 Query: 336 SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK 395 V FD + +Q+ + E+ + VL +PD L P +V+ L+EK Sbjct: 133 LGSDDLVNEAFD-----FAKNLCSLQLTEEEIALFSSAVLISPDRAWLLEPRKVQKLQEK 187 Query: 396 VYASLEAYCKHKYPEQPGRFAKLLLRLPALRSI 428 +Y +L+ + + + AKL+ ++P + ++ Sbjct: 188 IYFALQHVIQKNHLDDET-LAKLIAKIPTITAV 219 >1S0X-A nrPDB Length = 270 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 3/164 (1%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AKRI F EL +DQ++LL+AG E++ R+ ++ + G + + Sbjct: 81 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 139 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 S G V E + M + + E+ A VL + D L ++E L++K+ Sbjct: 140 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 198 Query: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 +L+ + + E G KL+ ++ LR++ + E L FK I Sbjct: 199 ALQHVLQKNHRE-DGILTKLICKVSTLRALCGRHTEKLMAFKAI 241 >5L7E-A nrPDB Length = 305 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 9/188 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S RS Sbjct: 47 PDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRS 106 Query: 318 IAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVL 375 + + A L + H + + + + + ++ + +Q+ E ++ ++L Sbjct: 107 YKHTNSQFLYFAPDLVFNEEKMHQSAMYEL-CQGMHQISLQFVRLQLTFEEYTIMKVLLL 165 Query: 376 FNPDSK-GLSNPAEVEALREKVYASLEAYCKHKYPEQPG----RFAKLLLRLPALRSIGL 430 + K GL + A E +R L K P G RF +L L ++ + Sbjct: 166 LSTIPKDGLKSQAAFEEMRTNYIKELRKMVT-KSPNNSGQSWQRFYQLTKLLDSMHDLVS 224 Query: 431 KCLEHLFF 438 LE F+ Sbjct: 225 DLLEFCFY 232 >2HCD-A nrPDB Length = 302 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 40/153 (26%), Positives = 80/153 (52%), Gaps = 3/153 (1%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG--LHVHRNS 336 ++ +AK IP F +L +DQ+ LL++ E+++ S++S +++D G N Sbjct: 118 VIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLR-SNQSFSLEDMSWSCGGPDFKYCIND 176 Query: 337 AHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV 396 AG L + ++ +++ + E L AI L +PD G+ + +EAL++++ Sbjct: 177 VTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRL 236 Query: 397 YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIG 429 L+AY + ++P +AK++ +L LRS+ Sbjct: 237 CDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLN 269 >3G8O-A nrPDB Length = 263 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 4/140 (2%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P + + +T++ Q ++QL ++V+W+K +P F L +DDQ+ L++ W L++ R Sbjct: 37 KPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWR 96 Query: 317 SIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLT--ELVSKMRDMQMDKTELGCLRAIV 374 S G +L + N + + LT ++ + +Q+ + E C++ ++ Sbjct: 97 SYKHVSGQMLYFAPDLILNEQRMKE-SSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLL 155 Query: 375 LFNPD-SKGLSNPAEVEALR 393 L N +GL + + E +R Sbjct: 156 LLNTIPLEGLRSQTQFEEMR 175 >3VHU-A nrPDB Length = 294 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 43/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S RS Sbjct: 69 PDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRS 128 Query: 318 IAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVL 375 + + A L + H + + + + + ++ + +Q+ E ++ ++L Sbjct: 129 YKHTNSQFLYFAPDLVFNEEKMHQSAMYELC-QGMHQISLQFVRLQLTFEEYTIMKVLLL 187 Query: 376 FNPDSK-GLSNPAEVEALREKVYASLEAY---CKHKYPEQPGRFAKLLLRLPALRSIGLK 431 + K GL + A E +R L C + + RF +L L ++ + Sbjct: 188 LSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSD 247 Query: 432 CLEHLFF 438 LE F+ Sbjct: 248 LLEFCFY 254 >2Q1H-A nrPDB Length = 250 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 36/140 (25%), Positives = 71/140 (50%), Gaps = 4/140 (2%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P + N ++++ + A KQ+ ++V+WAK +P F L LDDQ+ L++ W L+ S R Sbjct: 24 QPDTTNYLLSSLNRLAGKQMVSVVKWAKALPGFRNLHLDDQMTLIQYSWMSLMAFSLGWR 83 Query: 317 SIAVKDGILLATGLHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKTELGCLRAIV 374 S +G +L + N A++D + + ++ + +Q+ E C++ ++ Sbjct: 84 SYKHTNGQMLYFAPDLIFNEERMQQ-SAMYDLCQGMRQISQEFVRLQVTYEEFLCMKVLL 142 Query: 375 LFNPDSK-GLSNPAEVEALR 393 L + K GL + A + +R Sbjct: 143 LLSTVPKDGLKSQASFDEMR 162 >4OZR-E nrPDB Length = 197 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 46/152 (30%), Positives = 75/152 (49%), Gaps = 21/152 (13%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 +VE+AKR+P F +L +DQ+ LL+A +E+++ + R D IL Sbjct: 43 IVEFAKRLPGFDKLLREDQIALLKACSSEVMMLRMARRYDVGSDSIL------------- 89 Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398 A D +L +M M++D E L AIV+F+ + L +VE ++E Sbjct: 90 -----ATVDDLL-RFCRQMYGMKVDNAEYALLTAIVIFS-ERPSLIEGWKVEKIQEIYLE 142 Query: 399 SLEAYCKHKYPEQPGR-FAKLLLRLPALRSIG 429 +L+ Y ++ + G FAKLL L LR++G Sbjct: 143 ALKVYVDNRRKPRSGTIFAKLLSVLTELRTLG 174 >1RJK-A nrPDB Length = 292 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 38/155 (24%), Positives = 79/155 (50%), Gaps = 5/155 (3%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 ++ +AK IP F +L DDQ++LL++ E+++ S++S + D + Sbjct: 75 VIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLR-SNQSFTMDDMSWDCGSQDYKYDVTD 133 Query: 339 SAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV 396 + G + + L + ++ + + + E L AI + +PD G+ + VEA+++++ Sbjct: 134 VSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRL 193 Query: 397 YASLEAY--CKHKYPEQPGRFAKLLLRLPALRSIG 429 +L+ Y C+H P +AK++ +L LRS+ Sbjct: 194 SNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLN 228 >5GIE-A nrPDB Length = 256 Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 38/155 (24%), Positives = 79/155 (50%), Gaps = 5/155 (3%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 ++ +AK IP F +L DDQ++LL++ E+++ S++S + D + Sbjct: 74 VIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLR-SNQSFTMDDMSWDCGSQDYKYDVTD 132 Query: 339 SAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV 396 + G + + L + ++ + + + E L AI + +PD G+ + VEA+++++ Sbjct: 133 VSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRL 192 Query: 397 YASLEAY--CKHKYPEQPGRFAKLLLRLPALRSIG 429 +L+ Y C+H P +AK++ +L LRS+ Sbjct: 193 SNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLN 227 >1Y9R-A nrPDB Length = 255 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 9/188 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S RS Sbjct: 30 PDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLLSFALSWRS 89 Query: 318 IAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVL 375 + + A L + H + + + + + ++ + +Q+ E ++ ++L Sbjct: 90 YKHTNSQFLYFAPDLVFNEEKMHQSAMYEL-CQGMHQISLQFVRLQLTFEEYTIMKVLLL 148 Query: 376 FNPDSK-GLSNPAEVEALREKVYASLEAYCKHKYPEQPG----RFAKLLLRLPALRSIGL 430 + K GL + A E +R L K P G RF +L L ++ + Sbjct: 149 LSTIPKDGLKSQAAFEEMRTNYIKELRKMVT-KAPNNSGQSWQRFYQLTKLLDSMHDLVS 207 Query: 431 KCLEHLFF 438 LE F+ Sbjct: 208 DLLEFCFY 215 >3P8X-A nrPDB Length = 280 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/155 (23%), Positives = 78/155 (50%), Gaps = 5/155 (3%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 ++ +AK IP F +L +DQ++LL++ E+++ S+ S + D + Sbjct: 94 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLR-SNESFTMDDMSWTCGNQDYKYRVSD 152 Query: 339 SAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV 396 G + + L + ++ + + + E L AI + +PD G+ + A +EA+++++ Sbjct: 153 VTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRL 212 Query: 397 YASLEAY--CKHKYPEQPGRFAKLLLRLPALRSIG 429 +L+ Y C+H P +AK++ +L LRS+ Sbjct: 213 SNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLN 247 >5UC1-A nrPDB Length = 222 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 G P + +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L+ + Sbjct: 30 GTVPDTTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALG 89 Query: 315 HRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELV--SKMRDMQMDKTELGCLRA 372 RS G +L + N G+ ++D+ L S+++ +Q+ E C++ Sbjct: 90 WRSYRQSSGNVLCFAPDLIINE-QRMGLPYMYDQCKQMLFVSSELKRLQVSYEEYLCMKT 148 Query: 373 IVLFNPDSK-GLSNPAEVEALR 393 ++LF+ K GL + + +R Sbjct: 149 LLLFSSVPKEGLKSQELFDEIR 170 >2IHQ-A nrPDB Length = 260 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 48/197 (24%), Positives = 89/197 (45%), Gaps = 19/197 (9%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P S ++++ + ++QL +V+WAK +P F L +DDQ+ +++ W L++ + R Sbjct: 34 QPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWR 93 Query: 317 SIAVKDGILLATG-------LHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGC 369 S + +L +H++ +S V + L + +Q+ E C Sbjct: 94 SFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------MRHLSQEFGWLQITPQEFLC 147 Query: 370 LRAIVLFNPD-SKGLSNPAEVEALREKVYASLEAY--CKHKYPEQ-PGRFAKLLLRLPAL 425 ++A++LF+ GL N + LR L+ CK K P RF +L L ++ Sbjct: 148 MKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSV 207 Query: 426 RSIGLKCLEHLFFFKLI 442 + I + H F F L+ Sbjct: 208 QPIAREL--HQFTFDLL 222 >3HVL-A nrPDB Length = 344 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 52/184 (28%), Positives = 86/184 (46%), Gaps = 16/184 (8%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG-LHVHRNSA 337 ++ +AK I +F +LP++DQ+ LL+ EL F+ A TG R S Sbjct: 136 IISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNA-------ETGTWECGRLSY 188 Query: 338 HSAGVGAIFDRVLTELVSK----MRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR 393 F ++L E + K ++ +Q+ + E ++AI LF+PD G+ V+ L+ Sbjct: 189 CLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQ 248 Query: 394 EKVYASLEAY--CKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 451 E+ +L++Y C P F K++ L LRSI + + L + I P T L Sbjct: 249 EQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDI--HPFATPL 306 Query: 452 MEML 455 M+ L Sbjct: 307 MQEL 310 >3RY9-A nrPDB Length = 250 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 10/142 (7%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + N ++++ + +Q+ + V+WAK +P F L LDDQ+ LL+ W L+ S RS Sbjct: 25 PDTTNRLLSSLNRLGGRQMISAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRS 84 Query: 318 IAVKDGILL--ATGLHVHRNSAHSAGVGAI---FDRVLTELVSKMRDMQMDKTELGCLRA 372 +G +L A L + + + + ++ E V +Q+ E C++ Sbjct: 85 YQHTNGNMLYFAPDLIFNEERMQQSSMYELCKGMHKISLEFVR----LQVSYEEYLCMKV 140 Query: 373 IVLFNPDSK-GLSNPAEVEALR 393 ++L + K GL + A + +R Sbjct: 141 LLLLSTVPKDGLKSQAAFDEIR 162 >1XLS-E nrPDB Length = 242 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 7/182 (3%) Query: 254 MGLNPSSPNDPVT-NICQAADKQLFT---LVEWAKRIPHFSELPLDDQVILLRAGWNELL 309 M P P PV + AD F ++++ K +P F L ++DQ+ LL+ E+L Sbjct: 37 MHHRPFQPRGPVLPLLTHFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEIL 96 Query: 310 IASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGC 369 S + + + ++ H AG F + ++ + + + E Sbjct: 97 HISLNTTFCLQTENFFCGPLCYKMEDAVH-AGFQYEFLESILHFHKNLKGLHLQEPEYVL 155 Query: 370 LRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRF--AKLLLRLPALRS 427 + A LF+PD G++ E++ L+E++ L + + RF AKL+ L LRS Sbjct: 156 MAATALFSPDRPGVTQREEIDQLQEEMALILNNHIMEQQSRLQSRFLYAKLMGLLADLRS 215 Query: 428 IG 429 I Sbjct: 216 IN 217 >4E2J-A nrPDB Length = 250 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 68/139 (48%), Gaps = 4/139 (2%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + ++ + + +Q+ + V+WAK +P F L LDDQ+ LL+ W L+ S RS Sbjct: 27 PDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRS 86 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 +G +L + N + ++D+ + ++ S+ +Q+ E C++ ++L Sbjct: 87 YKQSNGNMLCFAPDLVINEER-MQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLL 145 Query: 376 FNPDSK-GLSNPAEVEALR 393 + K GL + A + +R Sbjct: 146 LSTVPKDGLKSQAVFDEIR 164 >3MNP-A nrPDB Length = 261 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 4/139 (2%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L++ + RS Sbjct: 37 PDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMVFALGWRS 96 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 G LL + N + ++D+ + + ++++ +Q+ E C++ ++L Sbjct: 97 YRQASGNLLCFAPDLIINE-QRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLL 155 Query: 376 FNPDSK-GLSNPAEVEALR 393 + K GL + + +R Sbjct: 156 LSSVPKEGLKSQELFDEIR 174 >5NFP-A nrPDB Length = 280 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L+ + RS Sbjct: 56 PDSTWRIMTTLNMLGGRQMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRS 115 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 LL + N + ++D+ + + S++ +Q+ E C++ ++L Sbjct: 116 YRQSSANLLCFAPDLIINE-QRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLL 174 Query: 376 FNPDSK-GLSNPAEVEALR 393 + K GL + + +R Sbjct: 175 LSSVPKDGLKSQELFDEIR 193 >5NTQ-A nrPDB Length = 238 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 8/118 (6%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA---TGLHVHRN 335 +VE+AKR+ F EL +DQ++LL+AG E+++ A + G+ + R Sbjct: 70 VVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA 129 Query: 336 SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR 393 S + +IFD + + + E+ A+VL N GL +VE L+ Sbjct: 130 LGCSELISSIFD-----FSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 182 >5NI5-A nrPDB Length = 288 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 8/118 (6%) Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA---TGLHVHRN 335 +VE+AKR+ F EL +DQ++LL+AG E+++ A + G+ + R Sbjct: 89 VVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA 148 Query: 336 SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR 393 S + +IFD + + + E+ A+VL N GL +VE L+ Sbjct: 149 LGCSELISSIFD-----FSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 201 >3UP0-A nrPDB Length = 243 Score = 32.3 bits (72), Expect = 0.44, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELL 309 N SP D + NI D + V+ AKR+P F++L D + LL+ G E+L Sbjct: 39 NEKSPAD-IMNIM---DVTMRRFVKMAKRLPAFNDLSQDGKFALLKGGMIEML 87 >6BUW-QI nrPDB Length = 128 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 361 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQP 412 Q+D +LG RA+V +NPD + P R+ + Y KHK P Sbjct: 73 QIDAIKLGIARALVQYNPDYRAKLKPLGF-LTRDARVVERKKYGKHKARRAP 123 >4NQ1-A nrPDB Length = 290 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLR 371 + GV ++ V +L++KM D+ MD + GCLR Sbjct: 198 AKGVISVTANVAAKLMAKMCDLAMDDDQAGCLR 230 >3ODW-A nrPDB Length = 536 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Query: 25 RGSMAAPSLHPSLG-PGIGSPGQLHSPISTLSSPIN--GMGPPFSV-ISSPMGP---HSM 77 +G + PS ++G PG +PG P+S L SP G P + SSP GP S+ Sbjct: 66 KGGVGMPSRDRNIGAPGQDTPGVSLHPLS-LDSPDREPGADAPLELGDSSPQGPMSLESL 124 Query: 78 SVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKP 109 + P + G T SP+ P S +++P Sbjct: 125 APPESTDEGAETESPEPGDEGEPGRSGLELEP 156 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3DZU-A nrPDB 772 0.0 4NQA-A nrPDB 595 e-170 6HN6-A nrPDB 388 e-108 5UAN-B nrPDB 385 e-107 4IQR-A nrPDB 377 e-105 6FX0-A nrPDB 372 e-103 4OC7-A nrPDB 360 e-100 1Z5X-U nrPDB 340 8e-94 2GL8-A nrPDB 337 7e-93 4NQA-B nrPDB 324 6e-89 1XIU-A nrPDB 323 1e-88 3DZU-D nrPDB 321 5e-88 5KYA-B nrPDB 319 2e-87 3EYB-A nrPDB 316 1e-86 5EC9-A nrPDB 316 1e-86 2Q60-A nrPDB 310 8e-85 1H9U-A nrPDB 305 3e-83 2NXX-A nrPDB 284 4e-77 4OZT-U nrPDB 270 8e-73 1XDK-B nrPDB 252 2e-67 1XAP-A nrPDB 244 5e-65 3A9E-B nrPDB 241 7e-64 5K13-A nrPDB 236 2e-62 1M7W-A nrPDB 236 2e-62 3CJW-A nrPDB 236 2e-62 1HG4-A nrPDB 234 4e-62 5M24-A nrPDB 234 6e-62 2P7A-A nrPDB 233 1e-61 4DOR-A nrPDB 231 4e-61 1PK5-A nrPDB 229 1e-60 3TX7-B nrPDB 229 3e-60 1LV2-A nrPDB 226 2e-59 6EU9-A nrPDB 226 2e-59 5KYJ-A nrPDB 223 1e-58 4UMM-F nrPDB 221 4e-58 6IAR-A nrPDB 218 5e-57 2OCF-A nrPDB 217 6e-57 4PXM-A nrPDB 216 1e-56 4OZT-E nrPDB 213 2e-55 1Z5X-E nrPDB 211 6e-55 2NXX-E nrPDB 210 1e-54 3FAL-B nrPDB 210 1e-54 2J7X-A nrPDB 209 2e-54 4LOG-A nrPDB 205 2e-53 1YMT-A nrPDB 205 2e-53 2YLY-A nrPDB 202 3e-52 3P0U-A nrPDB 201 5e-52 3K6P-A nrPDB 195 3e-50 1OVL-B nrPDB 195 4e-50 1R20-D nrPDB 194 5e-50 5LSG-A nrPDB 193 1e-49 2XHS-A nrPDB 191 4e-49 1PDU-A nrPDB 190 1e-48 4XAJ-A nrPDB 189 2e-48 2V0V-A nrPDB 189 3e-48 3V3Q-A nrPDB 186 2e-47 3D57-A nrPDB 185 3e-47 5Y44-A nrPDB 185 5e-47 4QJR-A nrPDB 184 6e-47 4N1Y-A nrPDB 184 9e-47 2H79-A nrPDB 184 1e-46 3UVV-A nrPDB 183 1e-46 1YJE-A nrPDB 183 1e-46 5L7E-A nrPDB 182 3e-46 3VHU-A nrPDB 181 5e-46 2Q1H-A nrPDB 180 7e-46 2XYJ-A nrPDB 180 1e-45 1OT7-A nrPDB 180 1e-45 3ET1-A nrPDB 179 3e-45 1Y9R-A nrPDB 179 3e-45 1YNW-B nrPDB 178 4e-45 3RY9-A nrPDB 178 5e-45 5NFP-A nrPDB 177 7e-45 4E2J-A nrPDB 175 3e-44 3MNP-A nrPDB 175 3e-44 5UC1-A nrPDB 175 5e-44 4OZR-E nrPDB 174 5e-44 5GIE-A nrPDB 173 2e-43 1RJK-A nrPDB 173 2e-43 2IHQ-A nrPDB 172 3e-43 3N00-A nrPDB 172 3e-43 2HCD-A nrPDB 170 8e-43 3P8X-A nrPDB 169 3e-42 4NUF-A nrPDB 165 4e-41 1XVP-B nrPDB 165 5e-41 3F5C-B nrPDB 163 1e-40 3HVL-A nrPDB 162 3e-40 4CN5-A nrPDB 160 8e-40 1XLS-E nrPDB 160 1e-39 3G8O-A nrPDB 160 1e-39 1S0X-A nrPDB 160 2e-39 5L0M-A nrPDB 153 2e-37 4UMM-A nrPDB 152 2e-37 4OLN-A nrPDB 152 4e-37 1R0O-B nrPDB 151 6e-37 1LO1-A nrPDB 150 1e-36 1N4H-A nrPDB 149 2e-36 5CBX-A nrPDB 149 2e-36 5CBZ-A nrPDB 148 3e-36 4UMM-E nrPDB 147 9e-36 5CC0-A nrPDB 147 1e-35 2FF0-A nrPDB 147 1e-35 5EMP-A nrPDB 146 2e-35 3CBB-A nrPDB 145 3e-35 4TNT-A nrPDB 144 6e-35 5NTQ-A nrPDB 144 8e-35 1HRA-A nrPDB 144 8e-35 4XAI-A nrPDB 144 8e-35 2NLL-B nrPDB 143 2e-34 5NI5-A nrPDB 142 2e-34 6CFN-A nrPDB 142 2e-34 1CIT-A nrPDB 142 4e-34 1LAT-A nrPDB 142 5e-34 2EBL-A nrPDB 140 9e-34 1GLU-A nrPDB 139 2e-33 1R4I-A nrPDB 139 2e-33 1A6Y-A nrPDB 139 2e-33 5KRB-B nrPDB 138 3e-33 2C7A-A nrPDB 138 5e-33 1KB2-A nrPDB 138 6e-33 1GDC-A nrPDB 137 9e-33 2NLL-A nrPDB 136 2e-32 4AA6-A nrPDB 136 2e-32 2ENV-A nrPDB 131 8e-31 Sequences not found previously or not previously below threshold: 3UP0-A nrPDB 58 1e-08 3ODW-A nrPDB 34 0.14 3J7R-j nrPDB 32 0.69 5LZY-j nrPDB 32 0.70 1JRP-B nrPDB 31 0.82 4V6U-Bk nrPDB 30 1.9 2KWQ-A nrPDB 30 2.5 3KYD-B nrPDB 30 3.2 3KYC-B nrPDB 30 3.2 5U1D-X nrPDB 30 3.2 3TR6-A nrPDB 30 3.2 3A1Y-G nrPDB 29 4.6 5W9Q-A nrPDB 29 4.9 5GAP-F nrPDB 29 4.9 >3DZU-A nrPDB Length = 467 Score = 772 bits (1994), Expect = 0.0, Method: Composition-based stats. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 11 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS 70 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS Sbjct: 16 FSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISS 75 Query: 71 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 130 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF Sbjct: 76 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 135 Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC Sbjct: 136 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 195 Query: 191 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV 250 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV Sbjct: 196 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV 255 Query: 251 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 310 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI Sbjct: 256 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 315 Query: 311 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL Sbjct: 316 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 375 Query: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL Sbjct: 376 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 435 Query: 431 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 462 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT Sbjct: 436 KCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 467 >4NQA-A nrPDB Length = 365 Score = 595 bits (1533), Expect = e-170, Method: Composition-based stats. Identities = 365/365 (100%), Positives = 365/365 (100%) Query: 98 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG 157 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG Sbjct: 1 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKG 60 Query: 158 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE 217 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE Sbjct: 61 FFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNE 120 Query: 218 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF Sbjct: 121 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 180 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 337 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA Sbjct: 181 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 240 Query: 338 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY Sbjct: 241 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 300 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA Sbjct: 301 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 360 Query: 458 PHQMT 462 PHQMT Sbjct: 361 PHQMT 365 >6HN6-A nrPDB Length = 282 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 201 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS 260 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS Sbjct: 21 KREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSS 80 Query: 261 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV 320 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV Sbjct: 81 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV 140 Query: 321 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS 380 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS Sbjct: 141 KDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS 200 Query: 381 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 440 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK Sbjct: 201 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 260 Query: 441 LIGDTPIDTFLMEMLEAPHQMT 462 LIGDTPIDTFLMEMLEAPHQMT Sbjct: 261 LIGDTPIDTFLMEMLEAPHQMT 282 >5UAN-B nrPDB Length = 397 Score = 385 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 115/346 (33%), Positives = 184/346 (53%), Gaps = 10/346 (2%) Query: 123 PSGNMASFTK--HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID 180 P G+ + C +C D+SSG HYGV +CEGCKGFF+R+++K++ YTC +K+C+I+ Sbjct: 16 PRGSHMPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVIN 75 Query: 181 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSS---ANEDMPVERILE 237 K RNRCQYCR QKC +GM +E+V+ +R + K + + S A D E+I + Sbjct: 76 KVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRK 135 Query: 238 AELAVEPKTETYVE----ANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELP 293 A P + ++ + A K + +VE+AKR+P F+ L Sbjct: 136 AHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLT 195 Query: 294 LDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTEL 353 + DQ+ LL+A ++LI R +D + + GL ++R H+AG G + D V T Sbjct: 196 IADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFT-F 254 Query: 354 VSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPG 413 +++ ++MD TE G L AI L D + L P +V+ L+E + +L+ Y + + P +P Sbjct: 255 ANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPH 314 Query: 414 RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 F K+L+++ LRSI K E + K+ + + EMLE Sbjct: 315 MFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE 360 >4IQR-A nrPDB Length = 338 Score = 377 bits (967), Expect = e-105, Method: Composition-based stats. Identities = 139/323 (43%), Positives = 198/323 (61%), Gaps = 8/323 (2%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +CAICGDR++GKHYG SC+GCKGFF+R+VRK+ Y+CR ++ C++DK +RN+C+YCR + Sbjct: 20 LCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLK 79 Query: 194 KCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMP-VERILEAELAVEPKTETYVEA 252 KC GMK+EAVQ ER R R +S + +P + +L+AE+ T Sbjct: 80 KCFRAGMKKEAVQNERDRISTRR------SSYEDSSLPSINALLQAEVLSRQITSPVSGI 133 Query: 253 NMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 N + + ++C++ +QL LVEWAK IP F ELPLDDQV LLRA E L+ Sbjct: 134 NGDIRAKKIAS-IADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLG 192 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 + RS+ KD +LL V R+ A + + R+L ELV +++Q+D E L+A Sbjct: 193 ATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKA 252 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I+ F+PD+KGLS+P +++ LR +V SLE Y + + GRF +LLL LP L+SI + Sbjct: 253 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 312 Query: 433 LEHLFFFKLIGDTPIDTFLMEML 455 +E + F KL G ID L EML Sbjct: 313 IEQIQFIKLFGMAKIDNLLQEML 335 >6FX0-A nrPDB Length = 454 Score = 372 bits (955), Expect = e-103, Method: Composition-based stats. Identities = 139/447 (31%), Positives = 212/447 (47%), Gaps = 62/447 (13%) Query: 36 SLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMG--PHSMSVPTTPTLGFSTGSPQ 93 +LGPG G PG G PF+ + G P M P+ LG P Sbjct: 13 ALGPGSGYPGA---------------GFPFAFPGALRGSPPFEMLSPSFRGLG----QPD 53 Query: 94 LSSPMNPVS------SSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHY 147 L M +S SSE++ VP+ PS C +C D+SSG HY Sbjct: 54 LPKEMASLSVETQSTSSEEM-----------VPSSPSPPPPPRVYKPCFVCNDKSSGYHY 102 Query: 148 GVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQE 207 GV SCEGCKGFF+R+++K++ YTC +K+C+I+K RNRCQYCR QKC +GM +EAV+ Sbjct: 103 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN 162 Query: 208 ERQR---------------GKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA 252 +R + + E + S A+++ + + V+ Sbjct: 163 DRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQL 222 Query: 253 NMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 ++GL + A K + +VE+AKR+P F+ L + DQ+ LL+A ++L+ Sbjct: 223 DLGL--------WDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLR 274 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 R +D + + GL ++R H+AG G + D V ++ ++MD TE G L A Sbjct: 275 ICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA-FAGQLLPLEMDDTETGLLSA 333 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I L D L P +V+ L+E + +L Y + + P QP F ++L+++ LR I K Sbjct: 334 ICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKG 393 Query: 433 LEHLFFFKLIGDTPIDTFLMEMLEAPH 459 E K+ P+ + EMLE P Sbjct: 394 AERAITLKMEIPGPMPPLIREMLENPE 420 >4OC7-A nrPDB Length = 254 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 240/240 (100%), Positives = 240/240 (100%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW Sbjct: 15 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 74 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV Sbjct: 75 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 134 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA Sbjct: 135 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 194 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 462 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT Sbjct: 195 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 254 >1Z5X-U nrPDB Length = 262 Score = 340 bits (872), Expect = 8e-94, Method: Composition-based stats. Identities = 187/260 (71%), Positives = 221/260 (85%), Gaps = 10/260 (3%) Query: 199 GMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNP 258 G KREAVQEERQR K+++ENEVESTS++ DMP+ERILEAEL VEPK E Sbjct: 10 GPKREAVQEERQRNKEKSENEVESTSNSQNDMPIERILEAELRVEPKNEDI--------- 60 Query: 259 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI 318 DPV++ICQAAD+QL+ L+EWAK IPHF+ELP++DQVILL++GWNELLIA FSHRS+ Sbjct: 61 -DSRDPVSDICQAADRQLYQLIEWAKHIPHFTELPVEDQVILLKSGWNELLIAGFSHRSM 119 Query: 319 AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP 378 +VKDGI+LATGL VHRN AH AGVGAIFDRVLTELV+KMR+M+MDKTELGCLR+IVLFNP Sbjct: 120 SVKDGIMLATGLVVHRNCAHQAGVGAIFDRVLTELVAKMREMKMDKTELGCLRSIVLFNP 179 Query: 379 DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF 438 ++KGL + +VE LREKVYA LE YC+ YP+Q GRFAKLLLRLPALRSIGLKCLEHLFF Sbjct: 180 EAKGLKSTQQVENLREKVYAILEEYCRQTYPDQSGRFAKLLLRLPALRSIGLKCLEHLFF 239 Query: 439 FKLIGDTPIDTFLMEMLEAP 458 FKL+G+T ID+FL+ MLE+ Sbjct: 240 FKLVGNTSIDSFLLSMLESN 259 >2GL8-A nrPDB Length = 241 Score = 337 bits (864), Expect = 7e-93, Method: Composition-based stats. Identities = 206/241 (85%), Positives = 225/241 (93%), Gaps = 3/241 (1%) Query: 222 STSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVE 281 + +S +EDMPVERILEAELAVEPKTE+Y + NM +S NDPVTNIC AADKQLFTLVE Sbjct: 4 NATSGHEDMPVERILEAELAVEPKTESYGDMNME---NSTNDPVTNICHAADKQLFTLVE 60 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG 341 WAKRIPHFS+L L+DQVILLRAGWNELLIASFSHRS++V+DGILLATGLHVHR+SAHSAG Sbjct: 61 WAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAG 120 Query: 342 VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLE 401 VG+IFDRVLTELVSKM+DMQMDK+ELGCLRAIVLFNPD+KGLSNP+EVE LREKVYA+LE Sbjct: 121 VGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLE 180 Query: 402 AYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQM 461 AY K KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE P Q+ Sbjct: 181 AYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQI 240 Query: 462 T 462 T Sbjct: 241 T 241 >4NQA-B nrPDB Length = 391 Score = 324 bits (830), Expect = 6e-89, Method: Composition-based stats. Identities = 93/375 (24%), Positives = 167/375 (44%), Gaps = 52/375 (13%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKD--LTYTCRDNKDCLIDKRQRNRCQYC 190 +C +CGD++SG HY V SCEGCKGFF+R+V + Y CR C +D R +CQ C Sbjct: 15 ELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQC 74 Query: 191 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTS-------------------------- 224 R +KC GM+ + V E Q K + + + S Sbjct: 75 RLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGG 134 Query: 225 ----------------SANEDMPVERILEAEL-------AVEPKTETYVEANMGLNPSSP 261 +A +++ +++++ A+L + +PK + + + Sbjct: 135 SEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDAR 194 Query: 262 NDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVK 321 + + A + +V++AK++P F +L +DQ+ LL+A E+++ + R Sbjct: 195 QQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHET 254 Query: 322 DGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSK 381 + I ++ H AG+ F + E MR + +D E L AI +F+ D Sbjct: 255 ECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRP 314 Query: 382 GLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441 + P VEAL++ +L +Y + K P+ RF ++L++L +LR++ E +F +L Sbjct: 315 NVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRL 374 Query: 442 IGDTPIDTFLMEMLE 456 + L E+ + Sbjct: 375 QDK-KLPPLLSEIWD 388 >1XIU-A nrPDB Length = 230 Score = 323 bits (828), Expect = 1e-88, Method: Composition-based stats. Identities = 193/237 (81%), Positives = 208/237 (87%), Gaps = 8/237 (3%) Query: 226 ANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKR 285 AN DMPVE+ILEAELAV+PK +TY++A DPVTNICQAADKQLFTLVEWAKR Sbjct: 2 ANNDMPVEQILEAELAVDPKIDTYIDAQ--------KDPVTNICQAADKQLFTLVEWAKR 53 Query: 286 IPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI 345 IPHF+ELPL+DQVILLRAGWNELLIA FSHRSI KDGILLATGLHVHR+SAH AGVG I Sbjct: 54 IPHFTELPLEDQVILLRAGWNELLIAGFSHRSIMAKDGILLATGLHVHRSSAHQAGVGTI 113 Query: 346 FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK 405 FDRVLTELV+KMRDM+MDKTELGCLRA+VLFNPD+KGL+ EVE LREKVYASLE Y K Sbjct: 114 FDRVLTELVAKMRDMKMDKTELGCLRAVVLFNPDAKGLTAVQEVEQLREKVYASLEEYTK 173 Query: 406 HKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 462 +YPE+PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD PIDTFLMEMLE P T Sbjct: 174 SRYPEEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDQPIDTFLMEMLENPSPAT 230 >3DZU-D nrPDB Length = 419 Score = 321 bits (822), Expect = 5e-88, Method: Composition-based stats. Identities = 108/371 (29%), Positives = 177/371 (47%), Gaps = 52/371 (14%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD++SG HYGV++CEGCKGFF+RT+R L Y R + +C I K+ RN+CQYCR+QK Sbjct: 53 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 111 Query: 195 CLAMGMKREAVQEER--QRGKDRNENEVEST------SSANEDMPVERILEAELAVEPKT 246 CLA+GM A++ R Q K++ E+ S SA+ + + ++ + P T Sbjct: 112 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 171 Query: 247 ETYVEANMGLNPSSPNDP-----VTNICQAADKQLFT----------------------- 278 + A + ++ P + ++ DK F Sbjct: 172 KAKARAIL-TGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFR 230 Query: 279 -------LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLH 331 + E+AK IP F L L+DQV LL+ G +E++ + S+ KDG+L++ G Sbjct: 231 SVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLA--SLMNKDGVLISEGQG 288 Query: 332 VHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 + D E K +++D ++L A+++ + D GL N + Sbjct: 289 FMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPI 348 Query: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449 E +++ + +LE K +PE FAKLL ++ LR I EH+ ++I T D Sbjct: 349 EDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEHVQLLQVIKKTETDM 405 Query: 450 FLMEMLEAPHQ 460 L +L+ ++ Sbjct: 406 SLHPLLQEIYK 416 >5KYA-B nrPDB Length = 256 Score = 319 bits (817), Expect = 2e-87, Method: Composition-based stats. Identities = 205/234 (87%), Positives = 214/234 (91%), Gaps = 2/234 (0%) Query: 226 ANEDMPVERILEAELAVEPKTETYVEANMGLNPSSP--NDPVTNICQAADKQLFTLVEWA 283 A E+MPV+RILEAELAVE K++ VE G S NDPVTNICQAADKQLFTLVEWA Sbjct: 4 APEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWA 63 Query: 284 KRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVG 343 KRIPHFS LPLDDQVILLRAGWNELLIASFSHRSI V+DGILLATGLHVHRNSAHSAGVG Sbjct: 64 KRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVG 123 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY 403 AIFDRVLTELVSKMRDM+MDKTELGCLRAI+LFNPD+KGLSNP+EVE LREKVYASLE Y Sbjct: 124 AIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETY 183 Query: 404 CKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 CK KYPEQ GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA Sbjct: 184 CKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 237 >3EYB-A nrPDB Length = 219 Score = 316 bits (810), Expect = 1e-86, Method: Composition-based stats. Identities = 191/227 (84%), Positives = 206/227 (90%), Gaps = 8/227 (3%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 DMPVE+I EAE+AVEPK VE PNDPVTNICQAADKQL TLVEWAKRIPH Sbjct: 1 DMPVEKIQEAEMAVEPKDGNMVE--------QPNDPVTNICQAADKQLVTLVEWAKRIPH 52 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 348 FS+LP+DDQVILLRAGWNELLIA+FSHRSI VKDGILLA+GLHVHR+SAH AGVG IFDR Sbjct: 53 FSDLPIDDQVILLRAGWNELLIAAFSHRSIDVKDGILLASGLHVHRSSAHQAGVGTIFDR 112 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 408 VLTELV+KMRDM+MDKTELGCLRAIVLFNPD+KGL++P+ VE+LREKVYASLE YCK +Y Sbjct: 113 VLTELVAKMRDMKMDKTELGCLRAIVLFNPDAKGLTDPSLVESLREKVYASLEEYCKQQY 172 Query: 409 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML Sbjct: 173 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 219 >5EC9-A nrPDB Length = 210 Score = 316 bits (810), Expect = 1e-86, Method: Composition-based stats. Identities = 210/228 (92%), Positives = 210/228 (92%), Gaps = 18/228 (7%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 DMPVERILEAELAVEP DPVTNICQAADKQLFTLVEWAKRIPH Sbjct: 1 DMPVERILEAELAVEP------------------DPVTNICQAADKQLFTLVEWAKRIPH 42 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 348 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR Sbjct: 43 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 102 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 408 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY Sbjct: 103 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 162 Query: 409 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE Sbjct: 163 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 210 >2Q60-A nrPDB Length = 258 Score = 310 bits (795), Expect = 8e-85, Method: Composition-based stats. Identities = 184/234 (78%), Positives = 202/234 (86%), Gaps = 4/234 (1%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 S+ N+DMPV++ILEAEL +PK E V + NDPV+NIC+AAD+QL TLVEW Sbjct: 22 ASNPNDDMPVDKILEAELISDPKVEQVVP----FEQVNENDPVSNICKAADRQLVTLVEW 77 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AKRIPHFS LPL+DQVILLRAGWNELLIASFSHRSI VKD ILLA+GLHVHR+SAH AGV Sbjct: 78 AKRIPHFSSLPLEDQVILLRAGWNELLIASFSHRSIDVKDSILLASGLHVHRHSAHQAGV 137 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 G IFDRVLTELVSKMRDM MDKTELGCLRA+VLFNPD K S+ A +E+LREKVYASLEA Sbjct: 138 GPIFDRVLTELVSKMRDMMMDKTELGCLRAVVLFNPDVKNPSDSAHIESLREKVYASLEA 197 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 YC+ KYP+QPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPID FLM MLE Sbjct: 198 YCRSKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDKFLMNMLE 251 >1H9U-A nrPDB Length = 224 Score = 305 bits (781), Expect = 3e-83, Method: Composition-based stats. Identities = 197/224 (87%), Positives = 205/224 (91%), Gaps = 2/224 (0%) Query: 230 MPVERILEAELAVEPKTETYVEANMGLNPSSP--NDPVTNICQAADKQLFTLVEWAKRIP 287 MPV+RILEAELAVE K++ VE G S NDPVTNICQAADKQLFTLVEWAKRIP Sbjct: 1 MPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIP 60 Query: 288 HFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFD 347 HFS LPLDDQVILLRAGWNELLIASFSHRSI V+DGILLATGLHVHRNSAHSAGVGAIFD Sbjct: 61 HFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFD 120 Query: 348 RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHK 407 RVLTELVSKMRDM+MDKTELGCLRAI+LFNPD+KGLSNP+EVE LREKVYASLE YCK K Sbjct: 121 RVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQK 180 Query: 408 YPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 451 YPEQ GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL Sbjct: 181 YPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 224 >2NXX-A nrPDB Length = 235 Score = 284 bits (728), Expect = 4e-77, Method: Composition-based stats. Identities = 153/234 (65%), Positives = 186/234 (79%), Gaps = 5/234 (2%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEW 282 TS+ DMP+ERI+EAE VE + + L + N V NICQA KQLF LV+W Sbjct: 2 TSNLQADMPLERIIEAEKRVECN-----DPLVALVVNENNTTVNNICQATHKQLFQLVQW 56 Query: 283 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV 342 AK +PHF+ LPL DQV LLRAGWNELLIA+FSHRS+ +D I+LATGL V++++AH+ GV Sbjct: 57 AKLVPHFTSLPLTDQVQLLRAGWNELLIAAFSHRSMQAQDAIVLATGLTVNKSTAHAVGV 116 Query: 343 GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA 402 G I+DRVL+ELV+KM++M+MDKTELGCLRAI+L+NPD +G+ + EVE LREK+Y LE Sbjct: 117 GNIYDRVLSELVNKMKEMKMDKTELGCLRAIILYNPDVRGIKSVQEVEMLREKIYGVLEE 176 Query: 403 YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 Y + +P +PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD PIDTFLMEMLE Sbjct: 177 YTRTTHPNEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDVPIDTFLMEMLE 230 >4OZT-U nrPDB Length = 195 Score = 270 bits (691), Expect = 8e-73, Method: Composition-based stats. Identities = 145/193 (75%), Positives = 167/193 (86%) Query: 263 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKD 322 + V NICQA + QL+ LVEWAK IPHFS LP++DQV+LLRAGWNELLIA+FSHRS+ V+D Sbjct: 1 NAVANICQATNSQLYQLVEWAKHIPHFSSLPIEDQVLLLRAGWNELLIAAFSHRSVEVRD 60 Query: 323 GILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKG 382 GI+L G+ VHRNSAH AGVG IFDRVLTELV+KMRDM MD+TELG LR+I+LFNP+ +G Sbjct: 61 GIVLGAGITVHRNSAHQAGVGTIFDRVLTELVAKMRDMNMDRTELGSLRSIILFNPEVRG 120 Query: 383 LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L + EVE LREKVYA+LE Y + PE+PGRFAKLLLRLPALRSIGLKCLEHLFFFKLI Sbjct: 121 LKSGQEVELLREKVYAALEEYTRVTRPEEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 180 Query: 443 GDTPIDTFLMEML 455 GD PIDTFLM+ML Sbjct: 181 GDIPIDTFLMDML 193 >1XDK-B nrPDB Length = 303 Score = 252 bits (645), Expect = 2e-67, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 127/267 (47%), Gaps = 8/267 (2%) Query: 200 MKREAVQEERQRGKDRNENEVESTSS---ANEDMPVERILEAELAVEPKTETYVE----A 252 M +E+V+ +R + K + + S A D E+I +A P + + Sbjct: 1 MSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNS 60 Query: 253 NMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 + + A K + +VE+AKR+P F+ L + DQ+ LL+A ++LI Sbjct: 61 SADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILR 120 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 R +D + + GL ++R H+AG G + D V T +++ ++MD TE G L A Sbjct: 121 ICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFT-FANQLLPLEMDDTETGLLSA 179 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I L D + L P +V+ L+E + +L+ Y + + P +P F K+L+++ LRSI K Sbjct: 180 ICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKG 239 Query: 433 LEHLFFFKLIGDTPIDTFLMEMLEAPH 459 E + K+ + + EMLE Sbjct: 240 AERVITLKMEIPGSMPPLIQEMLENSE 266 >1XAP-A nrPDB Length = 267 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 67/239 (28%), Positives = 115/239 (48%), Gaps = 9/239 (3%) Query: 221 ESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLV 280 E A+++ + + V ++GL + A K + +V Sbjct: 35 EKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGL--------WDKFSELATKCIIKIV 86 Query: 281 EWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA 340 E+AKR+P F+ L + DQ+ LL+A ++LI R +D + + GL ++R H+A Sbjct: 87 EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA 146 Query: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASL 400 G G + D V T +++ ++MD TE G L AI L D + L P +V+ L+E + +L Sbjct: 147 GFGPLTDLVFT-FANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEAL 205 Query: 401 EAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 + Y + + P +P F K+L+++ LRSI K E + K+ + + EMLE Sbjct: 206 KIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE 264 >3A9E-B nrPDB Length = 269 Score = 241 bits (614), Expect = 7e-64, Method: Composition-based stats. Identities = 70/267 (26%), Positives = 121/267 (45%), Gaps = 8/267 (2%) Query: 200 MKREAVQEERQRGKDRNENEVESTSS---ANEDMPVERILEAELAVEPKTETYVEANMG- 255 M +E+V+ +R + K S S +E++ +A P + Sbjct: 1 MSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNN 60 Query: 256 ---LNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIAS 312 S D + + K + VE+AK++P F+ L + DQ+ LL+A ++LI Sbjct: 61 SSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILR 120 Query: 313 FSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 R +D + + GL ++R H+AG G + D V +++ ++MD E G L A Sbjct: 121 ICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSA 179 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 I L D + L P V+ L+E + +L+ Y + + P +P F K+L+++ LRSI K Sbjct: 180 ICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKG 239 Query: 433 LEHLFFFKLIGDTPIDTFLMEMLEAPH 459 E + K+ + + EMLE Sbjct: 240 AERVITLKMEIPGSMPPLIQEMLENSE 266 >5K13-A nrPDB Length = 246 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 112/242 (46%), Gaps = 9/242 (3%) Query: 218 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 +E A+++ + +E V ++ D + + K + Sbjct: 6 ELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDI--------DLWDKFSELSTKCII 57 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 337 VE+AK++P F+ L + DQ+ LL+A ++LI R +D + + GL ++R Sbjct: 58 KTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQM 117 Query: 338 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 H+AG G + D V +++ ++MD E G L AI L D + L P V+ L+E + Sbjct: 118 HNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLL 176 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +L+ Y + + P +P F K+L+++ LRSI K E + K+ + + EMLE Sbjct: 177 EALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLEN 236 Query: 458 PH 459 Sbjct: 237 SE 238 >1M7W-A nrPDB Length = 250 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 94/244 (38%), Positives = 138/244 (56%), Gaps = 8/244 (3%) Query: 223 TSSANEDMP-VERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVE 281 +S + +P + +L+AE+ + T N + +T++C++ +QL LVE Sbjct: 1 SSYEDSSLPSINALLQAEVLSQQITSPISGINGDIRAKRIAS-ITDVCESMKEQLLVLVE 59 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG 341 WAK IP F EL LDDQV LLRA E L+ + RS+ KD +LL V R+ A Sbjct: 60 WAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAE 119 Query: 342 VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLE 401 + + R+L ELV +++Q+D E CL+AI+ F+PD+KGLS+P +++ LR +V SLE Sbjct: 120 MSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLE 179 Query: 402 AYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML------ 455 Y + + GRF +LLL LP L+SI + +E + F KL G ID L EML Sbjct: 180 DYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSAS 239 Query: 456 EAPH 459 +APH Sbjct: 240 DAPH 243 >3CJW-A nrPDB Length = 244 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 91/223 (40%), Positives = 132/223 (59%), Gaps = 3/223 (1%) Query: 236 LEAELAVEPKTETYVEANMGLNPSSPNDPVT--NICQAADKQLFTLVEWAKRIPHFSELP 293 L +++ + E Y + G PN+ + NIC+ A + LF+ VEWA+ IP F +L Sbjct: 8 LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ 67 Query: 294 LDDQVILLRAGWNELLIASFSHRSIAVKDGILLAT-GLHVHRNSAHSAGVGAIFDRVLTE 352 + DQV LLR W+EL + + + S+ + LLA GLH SA R+ E Sbjct: 68 ITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE 127 Query: 353 LVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQP 412 V K++ + +D E CL+AIVLF D+ GLS+ A VE+L+EK +LE Y + +YP QP Sbjct: 128 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP 187 Query: 413 GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 RF KLLLRLP+LR++ +E LFF +L+G TPI+T + +ML Sbjct: 188 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 230 >1HG4-A nrPDB Length = 279 Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 111/256 (43%), Positives = 154/256 (60%), Gaps = 32/256 (12%) Query: 223 TSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDP-----VTNICQAADKQLF 277 T+S + D +ERI+EAE E + + + P S P V+ +CQ +KQLF Sbjct: 2 TNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLF 61 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA------------------ 319 +VE+A+ +PHF+++PLDDQVILL+A W ELLIA+ + SI Sbjct: 62 QMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDG 121 Query: 320 ---------VKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370 + L HRNSA AGV AIFDR+L+EL KM+ + +D+ EL CL Sbjct: 122 SFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCL 181 Query: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430 +AI+L+NPD +G+ + AE+E REKVYA L+ +C+ ++P GRFA+LLLRLPALRSI L Sbjct: 182 KAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISL 241 Query: 431 KCLEHLFFFKLIGDTP 446 KC +HLF F++ D P Sbjct: 242 KCQDHLFLFRITSDRP 257 >5M24-A nrPDB Length = 250 Score = 234 bits (597), Expect = 6e-62, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 117/252 (46%), Gaps = 9/252 (3%) Query: 208 ERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTN 267 + + E + S A+++ + + V+ ++GL Sbjct: 5 DSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGL--------WDK 56 Query: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327 + A K + +VE+AKR+P F+ L + DQ+ LL+A ++L+ R +D + + Sbjct: 57 FSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFS 116 Query: 328 TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA 387 GL ++R H+AG G + D V ++ ++MD TE G L AI L D L P Sbjct: 117 DGLTLNRTQMHNAGFGPLTDLVFA-FAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPE 175 Query: 388 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI 447 +V+ L+E + +L Y + + PEQP F ++L+++ LR I K E K+ P+ Sbjct: 176 KVDKLQEPLLEALRLYARRRRPEQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPM 235 Query: 448 DTFLMEMLEAPH 459 + EMLE P Sbjct: 236 PPLIREMLENPE 247 >2P7A-A nrPDB Length = 251 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 74/235 (31%), Positives = 127/235 (54%), Gaps = 3/235 (1%) Query: 224 SSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWA 283 S P +I+ + L V + Y + + P S +T +C AD++L ++ WA Sbjct: 19 SHMPAKKPYNKIV-SHLLVAEPEKIYAMPDPTV-PDSDIKALTTLCDLADRELVVIIGWA 76 Query: 284 KRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVG 343 K IP FS L L DQ+ LL++ W E+LI +RS++ +D ++ A + + + AG+ Sbjct: 77 KHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLL 136 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY 403 + + +L +LV K + M+++K E L+AI L N DS + + V+ L++ ++ +L+ Y Sbjct: 137 DLNNAIL-QLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDY 195 Query: 404 CKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 458 ++ E P R K+L+ LP LR K ++H + KL G P+ +EMLEA Sbjct: 196 EAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAK 250 >4DOR-A nrPDB Length = 255 Score = 231 bits (590), Expect = 4e-61, Method: Composition-based stats. Identities = 85/248 (34%), Positives = 140/248 (56%), Gaps = 12/248 (4%) Query: 221 ESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPN-----DPVTNICQAADKQ 275 +++S A+ + +L+ E EP+ + + A + ++ + +C+ AD+ Sbjct: 8 QTSSPASIPHLILELLKCE-PDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQT 66 Query: 276 LFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV--KDGILLATGLHVH 333 LF++VEWA+ F EL +DDQ+ LL+ W+ELLI +R + + I L TG V Sbjct: 67 LFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVD 126 Query: 334 RNSAHSAGVGAIFDRVL---TELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVE 390 S ++ GA + ++ ELV+K+R +Q D+ E CL+ +VLF+ D K L N VE Sbjct: 127 Y-SIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVE 185 Query: 391 ALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF 450 ++E+V A+L Y YP+Q +F +LLLRLP +R+I ++ E+L++ L GD P + Sbjct: 186 GVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNL 245 Query: 451 LMEMLEAP 458 L+EML A Sbjct: 246 LIEMLHAK 253 >1PK5-A nrPDB Length = 248 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 86/247 (34%), Positives = 137/247 (55%), Gaps = 10/247 (4%) Query: 221 ESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPN-----DPVTNICQAADKQ 275 ++ S A+ + +L+ E EP+ + + A + S+ N +C+ AD+ Sbjct: 1 QTNSPASIPHLILELLKCE-PDEPQVQAKIMAYLQQEQSNRNRQEKLSAFGLLCKMADQT 59 Query: 276 LFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV--KDGILLATGLHVH 333 LF++VEWA+ F EL +DDQ+ LL+ W+ELLI +R +A + I L TG HV Sbjct: 60 LFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVD 119 Query: 334 RNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA 391 ++ S A + + ELV ++R +Q D+ E CL+ +VLF+ D K L N VE Sbjct: 120 YSTIISHTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENLQLVEG 179 Query: 392 LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 451 ++E+V A+L Y YP+Q +F +LLLRLP LR+I + ++L++ + GD P + L Sbjct: 180 VQEQVNAALLDYTVCNYPQQTEKFGQLLLRLPELRAISKQAEDYLYYKHVNGDVPYNNLL 239 Query: 452 MEMLEAP 458 +EML A Sbjct: 240 IEMLHAK 246 >3TX7-B nrPDB Length = 352 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 85/248 (34%), Positives = 140/248 (56%), Gaps = 12/248 (4%) Query: 221 ESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPN-----DPVTNICQAADKQ 275 +++S A+ + +L+ E EP+ + + A + ++ + +C+ AD+ Sbjct: 105 QTSSPASIPHLILELLKCE-PDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQT 163 Query: 276 LFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV--KDGILLATGLHVH 333 LF++VEWA+ F EL +DDQ+ LL+ W+ELLI +R + + I L TG V Sbjct: 164 LFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVD 223 Query: 334 RNSAHSAGVGAIFDRVL---TELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVE 390 S ++ GA + ++ ELV+K+R +Q D+ E CL+ +VLF+ D K L N VE Sbjct: 224 Y-SIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVE 282 Query: 391 ALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF 450 ++E+V A+L Y YP+Q +F +LLLRLP +R+I ++ E+L++ L GD P + Sbjct: 283 GVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNL 342 Query: 451 LMEMLEAP 458 L+EML A Sbjct: 343 LIEMLHAK 350 >1LV2-A nrPDB Length = 229 Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats. Identities = 88/225 (39%), Positives = 131/225 (58%), Gaps = 2/225 (0%) Query: 231 PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFS 290 + + +AE+ + + ++ +N + ++C++ +QL LVEWAK IP F Sbjct: 4 SINTLAQAEVRSRQISVSSPGSSTDINVKKIAS-IGDVCESMKQQLLVLVEWAKYIPAFC 62 Query: 291 ELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVL 350 ELPLDDQV LLRA E L+ + RS+ KD +LL +HRNS + + +RVL Sbjct: 63 ELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCE-VEISRVANRVL 121 Query: 351 TELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPE 410 ELV +++Q+D E CL+AIV F+PD+KGLS+P +++ +R +V LE Y + + Sbjct: 122 DELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYD 181 Query: 411 QPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 GRF +LLL LP L+SI + +E + F KL G ID L EML Sbjct: 182 SRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 226 >6EU9-A nrPDB Length = 241 Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats. Identities = 58/237 (24%), Positives = 115/237 (48%), Gaps = 3/237 (1%) Query: 222 STSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPND--PVTNICQAADKQLFTL 279 S + +E+ VE+IL+A P + + + + + + K + + Sbjct: 2 SELTEDEEEMVEKILKAHEETFPYLTDDDKYRLTQEELEKGNVILWERVSELSTKAIANV 61 Query: 280 VEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHS 339 V++ K++P F++L +DQ+ LL+A E++I + R +D + + GL + + Sbjct: 62 VDFGKQVPVFTQLSTNDQITLLKAACLEIIILRLASRYDDKEDTMSFSNGLTLTQQQLEV 121 Query: 340 AGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYAS 399 G G + + + + ++ +D E L I L + D GL +P +VE +E + + Sbjct: 122 GGFGTLTPTIF-KFARSLVELSVDTAEYAMLSLICLISGDRSGLEHPEKVEQKQEPILET 180 Query: 400 LEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 L+ Y + + P+ P FAKLLL+L LRS+ +K E + ++ + ++EML+ Sbjct: 181 LKHYVRKRRPDSPHSFAKLLLKLTDLRSLSVKGAERVLQLRMEMPGELPPLILEMLD 237 >5KYJ-A nrPDB Length = 287 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 55/239 (23%), Positives = 114/239 (47%), Gaps = 8/239 (3%) Query: 225 SANEDMPVERILEAEL-------AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 +A +++ +++++ A+L + +PK + + S+ + + A + Sbjct: 28 TAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPASGSASQQRFAHFTELAIISVQ 87 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 337 +V++AK++P F +L +DQ+ LL+A E+++ + R + I ++ Sbjct: 88 EIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDF 147 Query: 338 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 H AG+ F + E MR + +D E L AI +F+ D + P VEAL++ Sbjct: 148 HRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYV 207 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 +L +Y + K P+ RF ++L++L +LR++ E +F +L + L E+ + Sbjct: 208 EALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDK-KLPPLLSEIWD 265 >4UMM-F nrPDB Length = 264 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 109/254 (42%), Positives = 155/254 (61%), Gaps = 21/254 (8%) Query: 225 SANEDMPVERILEAELAVEPKTETYVEANMGLN---PSSPNDPVTNICQAADKQLFTLVE 281 +A +++ +ER+LE E V +E + +G + P PV+++CQ +KQ+ LV Sbjct: 1 AAVQELSIERLLEMESLVADPSEEFQFLRVGPDSNVPPKFRAPVSSLCQIGNKQIAALVV 60 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAV------------------KDG 323 WA+ IPHFS+L ++DQ++L++ WNELL+ + + RS+ Sbjct: 61 WARDIPHFSQLEMEDQILLIKGSWNELLLFAIAWRSMEFLTEERDGVDGTGNRTTSPPQL 120 Query: 324 ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL 383 + L G+ +HRNSA AGVG IFDRVL+EL KMR +++D+ E L+AI+L NPD KGL Sbjct: 121 MCLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRTLRVDQAEYVALKAIILLNPDVKGL 180 Query: 384 SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 443 N EVE LREK++ L+ YC+ + GRFA LLLRLPALRSI LK EHLFFF L+ Sbjct: 181 KNRQEVEVLREKMFLCLDEYCRRSRSSEEGRFAALLLRLPALRSISLKSFEHLFFFHLVA 240 Query: 444 DTPIDTFLMEMLEA 457 DT I ++ + L Sbjct: 241 DTSIAGYIRDALRN 254 >6IAR-A nrPDB Length = 237 Score = 218 bits (555), Expect = 5e-57, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 112/240 (46%), Gaps = 17/240 (7%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 + ++++ A L EP +P+ P + + AD++L ++ WAKR+P Sbjct: 3 SLTADQMVSALLDAEPPI-----LYSEYDPTRPFSMMGLLTNLADRELVHMINWAKRVPG 57 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVGAIFD 347 F +L L DQV LL + W E+L+ RS+ +L A L + RN S G+ IFD Sbjct: 58 FVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKSVEGMVEIFD 117 Query: 348 RVLTELVSKMRDMQMDKTELGCLRAIVL-------FNPDSKGLSNPAEVEALREKVYASL 400 +L S+ R M + E CL++I+L F+ K L + + +K+ +L Sbjct: 118 MLLAT-SSRFRMMNLQGEEFVCLKSIILLNSGVYTFSSTLKSLEEKDHIHRVLDKITDTL 176 Query: 401 EAYCKH---KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +Q R A+LLL L +R + K +EHL+ K P L+EML+A Sbjct: 177 IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEMLDA 236 >2OCF-A nrPDB Length = 298 Score = 217 bits (554), Expect = 6e-57, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 114/251 (45%), Gaps = 15/251 (5%) Query: 219 EVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFT 278 + +S + ++++ A L EP Y E + P S + + AD++L Sbjct: 2 KRSKKNSLALSLTADQMVSALLDAEPPIL-YSEYDP-TRPFSEASMMGLLTNLADRELVH 59 Query: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338 ++ WAKR+P F +L L DQV LL W E+L+ RS+ +L A L + RN Sbjct: 60 MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGK 119 Query: 339 SA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS--------KGLSNPAEV 389 G+ IFD +L S+ R M + E CL++I+L N K L + Sbjct: 120 CVEGMVEIFDMLLAT-SSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 178 Query: 390 EALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP 446 + +K+ +L +Q R A+LLL L +R + K +EHL+ K P Sbjct: 179 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 238 Query: 447 IDTFLMEMLEA 457 + L+EML+A Sbjct: 239 LSDLLLEMLDA 249 >4PXM-A nrPDB Length = 271 Score = 216 bits (551), Expect = 1e-56, Method: Composition-based stats. Identities = 75/260 (28%), Positives = 114/260 (43%), Gaps = 19/260 (7%) Query: 210 QRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNIC 269 Q + + S D V +L+AE P Y E + P S + + Sbjct: 11 QSNAMKRSKKNSLALSLTADQMVSALLDAE----PPIL-YSEYDP-TRPFSEASMMGLLT 64 Query: 270 QAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG 329 AD++L ++ WAKR+P F +L L DQV LL W E+L+ RS+ +L A Sbjct: 65 NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN 124 Query: 330 LHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS-------- 380 L + RN G+ IFD +L S+ R M + E CL++I+L N Sbjct: 125 LLLDRNQGKCVEGMVEIFDMLLAT-SSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTL 183 Query: 381 KGLSNPAEVEALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGLKCLEHLF 437 K L + + +K+ +L +Q R A+LLL L +R + K +EHL+ Sbjct: 184 KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLY 243 Query: 438 FFKLIGDTPIDTFLMEMLEA 457 K P+ L+EML+A Sbjct: 244 SMKCKNVVPLYGLLLEMLDA 263 >4OZT-E nrPDB Length = 238 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 108/236 (45%), Gaps = 7/236 (2%) Query: 225 SANEDMPVERILEAELAVEPKTET---YVEANMGLNPSSPNDPVTNICQAADKQLFTLVE 281 S ++ + R++ + E ++ + + +I + + +VE Sbjct: 5 SPEQEELIHRLVYFQNEYEQPSDEDLKRISNTPSEGEDQSDLNFRHITEITILTVQLIVE 64 Query: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG 341 +AKR+P F +L +DQ+ LL+A +E+++ + R D IL A R+S AG Sbjct: 65 FAKRLPGFDKLLREDQIALLKACSSEVMMLRMARRYDVGSDSILFANNQPYTRDSYSLAG 124 Query: 342 VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLE 401 +G D +L +M M++D E L AIV+F+ + L +VE ++E +L+ Sbjct: 125 MGETVDDLL-RFCRQMYGMKVDNAEYALLTAIVIFS-ERPSLIEGWKVEKIQEIYLEALK 182 Query: 402 AYCKHKY-PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 Y ++ P FAKLL L LR++G E F KL + FL E+ + Sbjct: 183 VYVDNRRKPASGTIFAKLLSVLTELRTLGNLNSEMCFSLKLKNK-KLPPFLAEIWD 237 >1Z5X-E nrPDB Length = 310 Score = 211 bits (537), Expect = 6e-55, Method: Composition-based stats. Identities = 73/294 (24%), Positives = 135/294 (45%), Gaps = 22/294 (7%) Query: 172 RDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTS-----SA 226 R K DK + N C + +++E + ++++ S + + Sbjct: 27 RKEKKAQKDKDKPNSTTSC----------SPDGIKQEIDPQRLDTDSQLLSVNGVKPITP 76 Query: 227 NEDMPVERILEAELAVEPKTETYVEANMGLNPSSPN---DPVTNICQAADKQLFTLVEWA 283 ++ + R++ + E + ++ + P N + +I + + +VE++ Sbjct: 77 EQEELIHRLVYFQNEYEHPSPEDIKRIVNAAPEEENVAEERFRHITEITILTVQLIVEFS 136 Query: 284 KRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVG 343 KR+P F +L +DQ+ LL+A +E+++ + R A D IL AT R S AG+G Sbjct: 137 KRLPGFDKLIREDQIALLKACSSEVMMFRMARRYDAETDSILFATNQPYTRESYTVAGMG 196 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY 403 + +L M M++D E L AIV+F+ + LS +VE ++E +L+AY Sbjct: 197 DTVEDLL-RFCRHMCAMKVDNAEYALLTAIVIFS-ERPSLSEGWKVEKIQEIYIEALKAY 254 Query: 404 CKHKY-PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 +++ P FAKLL L LR++G E F KL + + +FL E+ + Sbjct: 255 VENRRKPYATTIFAKLLSVLTELRTLGNMNSETCFSLKL-KNRKVPSFLEEIWD 307 >2NXX-E nrPDB Length = 248 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 65/241 (26%), Positives = 112/241 (46%), Gaps = 9/241 (3%) Query: 225 SANEDMPVERIL----EAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLV 280 S ++ + R++ E E E + + M + +I + + +V Sbjct: 11 SPEQEELIHRLVYFQNEYEHPSEEDVKRIINQPMDGE-DQCDVRFRHITEITILTVQLIV 69 Query: 281 EWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA 340 E+AKR+P F +L +DQ+ LL+A +E+++ + R D IL R+S + A Sbjct: 70 EFAKRLPGFDKLLREDQIALLKACSSEVMMFRMARRYDVQTDSILFVNNQPYSRDSYNLA 129 Query: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASL 400 G+G + +L M M++D E L AIV+F+ + L +VE ++E +L Sbjct: 130 GMGETIEDLL-HFCRTMYSMRVDNAEYALLTAIVIFS-ERPALIEGWKVEKIQEIYLEAL 187 Query: 401 EAYCKHKYPEQPG-RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 AY ++ +PG FAKLL L LR++G + E F KL + FL E+ + Sbjct: 188 RAYVDNRRKPKPGTIFAKLLSVLTELRTLGNQNSEMCFSLKLKNK-KLPPFLAEIWDVDL 246 Query: 460 Q 460 + Sbjct: 247 K 247 >3FAL-B nrPDB Length = 266 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 50/239 (20%), Positives = 104/239 (43%), Gaps = 8/239 (3%) Query: 225 SANEDMPVERILEAEL-------AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 S + +E+++ A+ + + + A + + + + A + Sbjct: 26 SPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQ 85 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA 337 +V++AK++P F +L +DQ+ LL+ E+++ S R + I +R Sbjct: 86 EIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDF 145 Query: 338 HSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 AG+ F + E M ++Q++ E L AI +F+ D + + +VE L+ Sbjct: 146 AKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYV 205 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 +L AY +P P F ++L++L +LR++ E +F +L + L E+ + Sbjct: 206 EALHAYVSINHPHDPLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDK-KLPPLLSEIWD 263 >2J7X-A nrPDB Length = 255 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 69/244 (28%), Positives = 110/244 (45%), Gaps = 19/244 (7%) Query: 232 VERILEAELAVEPKTETYVEANMG-------LNPSSPNDPVTNICQAADKQLFTLVEWAK 284 V+ +L + L+ E T +EA P + + ++ + ADK+L ++ WAK Sbjct: 1 VKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAK 60 Query: 285 RIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVG 343 +IP F EL L DQV LL + W E+L+ RSI ++ A L + R+ G+ Sbjct: 61 KIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGIL 120 Query: 344 AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY 403 IFD +L R++++ E C++A++L N L++ + K+ L A Sbjct: 121 EIFDMLLATTSR-FRELKLQHKEYLCVKAMILLNSSMYPLASANQEAESSRKLTHLLNAV 179 Query: 404 CKH----------KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLME 453 +Q R A LL+ L +R I K +EHL K P+ L+E Sbjct: 180 TDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLE 239 Query: 454 MLEA 457 ML A Sbjct: 240 MLNA 243 >4LOG-A nrPDB Length = 574 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 78/212 (36%), Positives = 120/212 (56%), Gaps = 1/212 (0%) Query: 247 ETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWN 306 +T EA ++ + + +I + + + LF V+WAK +P FS LP DQVILL W+ Sbjct: 357 QTVDEALKDAQTNAAAEFLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWS 416 Query: 307 ELLIASFSHRSIAVKDGILLATGLHVHRNSAH-SAGVGAIFDRVLTELVSKMRDMQMDKT 365 EL + S+ + LLA A + ++ RVL E +S+ R + +D T Sbjct: 417 ELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPT 476 Query: 366 ELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPAL 425 E C++A+VLF P+++GL +P VEAL+++ L + K +P QP RF KLLL LP+L Sbjct: 477 EFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSL 536 Query: 426 RSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 R I + +E LFF K IG+TP++ L +M + Sbjct: 537 RFITAERIELLFFRKTIGNTPMEKLLSDMFKN 568 >1YMT-A nrPDB Length = 246 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 7/224 (3%) Query: 243 EPKTETYVEANMGLNPSSPND---PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVI 299 E + + + S +D P + +C+ AD+ ++V+WA+R F EL + DQ+ Sbjct: 22 EDQVRARIVGCLQEPAKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMT 81 Query: 300 LLRAGWNELLIASFSHRSIAV--KDGILLATGLHVHRNSAHSAGVGAIFDRVL--TELVS 355 LL+ W+ELL+ +R + +D ILL TG V ++ + VL ELV Sbjct: 82 LLQNSWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVL 141 Query: 356 KMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRF 415 ++ +Q+D+ E CL+ ++LF+ D K L+N + V+ +EK A+L Y YP +F Sbjct: 142 QLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLSHYPHSGDKF 201 Query: 416 AKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 +LLL L +R++ ++ E+L+ L + P + L+EML+A Sbjct: 202 QQLLLSLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQ 245 >2YLY-A nrPDB Length = 240 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 65/240 (27%), Positives = 110/240 (45%), Gaps = 14/240 (5%) Query: 228 EDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIP 287 + + E+++ L EP +V + P + + ++ + ADK+L ++ WAK+IP Sbjct: 2 DALSPEQLVLTLLEAEP---PHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIP 58 Query: 288 HFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA-GVGAIF 346 F EL L DQV LL + W E+L+ RSI ++ A L + R+ G+ IF Sbjct: 59 GFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIF 118 Query: 347 DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY------ASL 400 D +L R++++ E C++A++L N L + ++ R+ + +L Sbjct: 119 DMLLATTSR-FRELKLQHKEYLCVKAMILLNSSMYPLVTATQDDSSRKLAHLLNAVTDAL 177 Query: 401 EAYCKH---KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 +Q R A LL+ L +R K +EHL K P+ L+EML A Sbjct: 178 VWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNA 237 >3P0U-A nrPDB Length = 249 Score = 201 bits (512), Expect = 5e-52, Method: Composition-based stats. Identities = 74/250 (29%), Positives = 117/250 (46%), Gaps = 20/250 (8%) Query: 227 NEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRI 286 ++ P+ +E L + + +P V IC++A + LF + WA+ I Sbjct: 2 DQSTPIIE-VEGPLLSDTHVTFKLTMP---SPMPEYLNVHYICESASRLLFLSMHWARSI 57 Query: 287 PHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF 346 P F L D L+RA WNEL + + + +LA ++ +NS + Sbjct: 58 PAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSG-- 115 Query: 347 DRV---------LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVY 397 DR+ L E + M + +D E L+AIVLF+PD GL++ +++E +E Sbjct: 116 DRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEAAQ 175 Query: 398 ASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL-----M 452 L+ Y + Y E R A++L+RLPALR + E LFF LIG+ ID+ + M Sbjct: 176 MELQDYVQATYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKM 235 Query: 453 EMLEAPHQMT 462 E E Q+T Sbjct: 236 ETAEYNGQIT 245 >3K6P-A nrPDB Length = 248 Score = 195 bits (497), Expect = 3e-50, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 116/233 (49%), Gaps = 7/233 (3%) Query: 229 DMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPH 288 PV ++ L VEP E P V +C D+++ + WAK IP Sbjct: 16 QGPVNALVSHLLVVEP--EKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPG 73 Query: 289 FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR 348 FS L L DQ+ +L++ W E+L+ + RS+ ++D + A L + A +AG+G + Sbjct: 74 FSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAA 133 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY----C 404 +L +LV +++ +++++ E L+A+ L N DS + + VE LRE ++ +L Y Sbjct: 134 LL-QLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRA 192 Query: 405 KHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 + R +LLL LP LR K L H + KL G P+ +EMLEA Sbjct: 193 GPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA 245 >1OVL-B nrPDB Length = 271 Score = 195 bits (495), Expect = 4e-50, Method: Composition-based stats. Identities = 60/272 (22%), Positives = 119/272 (43%), Gaps = 19/272 (6%) Query: 200 MKREAVQEERQRGKD-----RNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANM 254 M +E V+ + +G+ + ++ E + + + ++ A + P + + Sbjct: 1 MVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRF 60 Query: 255 GLNPS-----SPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELL 309 NP + + + WA++IP F++LP DQ +L + + EL Sbjct: 61 QANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELF 120 Query: 310 IASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGC 369 + ++RS V+ ++ G+ +HR G G D + E S +++M +D + C Sbjct: 121 VLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSI-VEFSSNLQNMNIDISAFSC 178 Query: 370 LRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYP--EQPGRFAKLLLRLPALRS 427 + A+ + + GL P VE L+ K+ L+ + +P +KLL +LP LR+ Sbjct: 179 IAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRT 237 Query: 428 IGLKCLEHLFFFKLIGDTP----IDTFLMEML 455 + + L+ +F+ KL P ID ++ L Sbjct: 238 LCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 269 >1R20-D nrPDB Length = 265 Score = 194 bits (494), Expect = 5e-50, Method: Composition-based stats. Identities = 58/240 (24%), Positives = 108/240 (45%), Gaps = 11/240 (4%) Query: 225 SANEDMPVERILEAELAVEPKTETYVEANMGL-----NPSSPNDPVTNICQAADKQLFTL 279 +AN+ + R++ + E +E ++ + + P I + + + Sbjct: 24 TANQKSLIARLVYYQEGYEQPSEEDLKRVTQTWQSDEDDEDSDMPFRQITEMTILTVQLI 83 Query: 280 VEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHS 339 VE+AK +P FS++ DQ+ LL+A +E+++ + R A D +L A R++ Sbjct: 84 VEFAKGLPGFSKISQSDQITLLKACSSEVMMLRVARRYDAATDSVLFANNQAYTRDNYRK 143 Query: 340 AGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYAS 399 AG+ + + +L M M MD L AIV+F+ D GL P+ VE ++ + Sbjct: 144 AGMAYVIEDLL-HFCRCMYSMMMDNVHYALLTAIVIFS-DRPGLEQPSLVEEIQRYYLNT 201 Query: 400 LEAYCKHKYPEQPG---RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 L Y ++ P F K+L L +R++G++ KL + + FL E+ + Sbjct: 202 LRVYILNQNSASPRSAVIFGKILGILTEIRTLGMQNSNMCISLKL-KNRKLPPFLEEIWD 260 >5LSG-A nrPDB Length = 304 Score = 193 bits (491), Expect = 1e-49, Method: Composition-based stats. Identities = 61/276 (22%), Positives = 113/276 (40%), Gaps = 43/276 (15%) Query: 222 STSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDP-----VTNICQAADKQL 276 + SA+ + + ++ + P T+ A + ++ P + ++ DK Sbjct: 32 NPESADLRALAKHLYDSYIKSFPLTKAKARAIL-TGKTTDKSPFVIYDMNSLMMGEDKIK 90 Query: 277 FT------------------------------LVEWAKRIPHFSELPLDDQVILLRAGWN 306 F + E+AK IP F L L+DQV LL+ G + Sbjct: 91 FKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH 150 Query: 307 ELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDK 364 E++ + S+ KDG+L++ G + D E K +++D Sbjct: 151 EIIYTMLA--SLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDD 208 Query: 365 TELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPA 424 ++L A+++ + D GL N +E +++ + +LE K +PE FAKLL ++ Sbjct: 209 SDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTD 268 Query: 425 LRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQ 460 LR I EH+ ++I T D L +L+ ++ Sbjct: 269 LRQI---VTEHVQLLQVIKKTETDMSLHPLLQEIYK 301 >2XHS-A nrPDB Length = 245 Score = 191 bits (486), Expect = 4e-49, Method: Composition-based stats. Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 3/232 (1%) Query: 231 PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFS 290 + +++ E +T+ + D +C+ D+ LF+ V+WA+ F Sbjct: 14 MIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFK 73 Query: 291 ELPLDDQVILLRAGWNELLIASFSHRSIAV--KDGILLATGLHVHRNSAHSAGVGAIFDR 348 +L +DDQ+ LL+ W+++L+ H I D L G + S GV + D Sbjct: 74 DLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGD- 132 Query: 349 VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY 408 EL +K++D++ D + C++ ++L NP +G+ N V + V A+L Y Y Sbjct: 133 YFNELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCY 192 Query: 409 PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQ 460 P +F L+ LP + ++ ++ +HL+ G P T LMEML A + Sbjct: 193 PSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHCAGSAPTQTLLMEMLHAKRK 244 >1PDU-A nrPDB Length = 244 Score = 190 bits (483), Expect = 1e-48, Method: Composition-based stats. Identities = 49/228 (21%), Positives = 102/228 (44%), Gaps = 5/228 (2%) Query: 230 MPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHF 289 + ++ + + P ++ S D V Q + + ++A++IP + Sbjct: 14 SLITALVRSHVDTTPDPSCLDYSHYEEQSMSEADKVQQFYQLLTSSVDVIKQFAEKIPGY 73 Query: 290 SELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV 349 +L +DQ +L ++ EL + ++R+ ++ G +HR + G + + Sbjct: 74 FDLLPEDQELLFQSASLELFVLRLAYRARIDDTKLIFCNGTVLHRTQCLRS-FGEWLNDI 132 Query: 350 LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYP 409 + E + ++++D + CL A+ L + GL P +VE L+ K+ SL + + Sbjct: 133 M-EFSRSLHNLEIDISAFACLCALTLIT-ERHGLREPKKVEQLQMKIIGSLRDHVTYNAE 190 Query: 410 EQ--PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 Q F++LL +LP LRS+ ++ L+ +F+ KL P + M Sbjct: 191 AQKKQHYFSRLLGKLPELRSLSVQGLQRIFYLKLEDLVPAPALIENMF 238 >4XAJ-A nrPDB Length = 576 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 74/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%) Query: 247 ETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWN 306 +T EA ++ + ++C++A + LF ++WAK +P FS L L DQ++LL W Sbjct: 357 QTVDEALKDAQTNAAAEFTESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWR 416 Query: 307 ELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDK 364 EL + + +I V LLA ++ ++ S + I + L E+V++ R +++D Sbjct: 417 ELFVLGIAQWAIPVDANTLLAVS-GMNGDNTDSQRLTLIISEIQALQEVVARFRQLRLDA 475 Query: 365 TELGCLRAIVLFN-------PDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAK 417 TE CL+ IV F + + N A + AL+++ +L +Y +YP QP RF K Sbjct: 476 TEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPVRFGK 535 Query: 418 LLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457 LLL LPALRSI +E +FF K IG+ PI L +M ++ Sbjct: 536 LLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKS 575 >2V0V-A nrPDB Length = 194 Score = 189 bits (479), Expect = 3e-48, Method: Composition-based stats. Identities = 56/183 (30%), Positives = 88/183 (48%), Gaps = 1/183 (0%) Query: 259 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI 318 S ++ + + +VE+AKRIP F +L DQV LL+AG E+L+ F+ Sbjct: 11 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD 70 Query: 319 AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP 378 A + + + HS G G + + + E K+ +Q+ E+ A+VL + Sbjct: 71 AKERTVTFLGSKKYSVDDLHSMGAGDLLNS-MFEFSEKLNALQLSDEEMSLFTAVVLVSA 129 Query: 379 DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF 438 D G+ N VEAL+E + +L +P + F KLLL+LP LRS+ E L Sbjct: 130 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 189 Query: 439 FKL 441 FK+ Sbjct: 190 FKV 192 >3V3Q-A nrPDB Length = 257 Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats. Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 14/232 (6%) Query: 235 ILEAELAVEPKT-----ETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHF 289 ++ A L P T + E + V L + +WA++IP F Sbjct: 19 LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGF 78 Query: 290 SELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV 349 +EL DQ +LL + + EL I ++RS + ++ +GL +HR G G D + Sbjct: 79 AELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCAR-GFGDWIDSI 137 Query: 350 LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK--HK 407 L + + +D CL A+VL D GL P VE L+ ++ + L+ + Sbjct: 138 LA-FSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAG 195 Query: 408 YPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEML 455 P+ ++LL +LP LR++ + L+ +F+ KL P ID M+ L Sbjct: 196 EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 247 >3D57-A nrPDB Length = 266 Score = 185 bits (471), Expect = 3e-47, Method: Composition-based stats. Identities = 56/259 (21%), Positives = 108/259 (41%), Gaps = 8/259 (3%) Query: 199 GMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNP 258 G K E EE + K E V + + + + L ++ P + L Sbjct: 15 GHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLE- 73 Query: 259 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI 318 ++ + + +V++AK++P F ELP +DQ+ILL+ E++ + R Sbjct: 74 -----AFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYD 128 Query: 319 AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP 378 + + L + V R + G+G + D + L + +D TE+ L+A++L + Sbjct: 129 PESETLTLNGEMAVTRGQLKNGGLGVVSDAIF-RLGMSLSSFNLDDTEVALLQAVLLMSS 187 Query: 379 DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF 438 D GL+ +E ++ + E Y ++ + KLL+++ LR IG Sbjct: 188 DRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLH 247 Query: 439 FKLIGDTPI-DTFLMEMLE 456 K+ T + +E+ E Sbjct: 248 MKVECPTELFPPLFLEVFE 266 >5Y44-A nrPDB Length = 227 Score = 185 bits (469), Expect = 5e-47, Method: Composition-based stats. Identities = 51/232 (21%), Positives = 101/232 (43%), Gaps = 8/232 (3%) Query: 225 SANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAK 284 + ++ + I+++ + + + + S + + + A + LVE+ K Sbjct: 3 TPDQQTLLHFIMDSY--NKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTK 60 Query: 285 RIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGA 344 ++P F L +DQ+ LL+ E + RS + + L + + ++G+ Sbjct: 61 KLPGFQTLDHEDQIALLKGSAVEAMFL----RSAEIFNKKLPSGHSDLLEERIRNSGISD 116 Query: 345 IFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYC 404 + + + +++M + E L AIV+ +PD + + + VE L+E + L+ C Sbjct: 117 EYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLC 176 Query: 405 KHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 K PE P FAKLL RL LR+ E L +++ D L E+ + Sbjct: 177 KIHQPENPQHFAKLLGRLTELRTFNHHHAEMLMSWRV--DHKFTPLLQEIWD 226 >4QJR-A nrPDB Length = 245 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 69/225 (30%), Positives = 115/225 (51%), Gaps = 5/225 (2%) Query: 239 ELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQV 298 E V + ++ P P +C+ AD+ ++V+WA+R F EL + DQ+ Sbjct: 21 EDQVRARILGSLQEPTKSRPDQPA-AFGLLCRMADQTFISIVDWARRCMVFKELEVADQM 79 Query: 299 ILLRAGWNELLIASFSHRSIAV--KDGILLATGLHVHRNSAHSAGVGAIFDRVLT--ELV 354 LL+ W+ELL+ +R + + ILL TG V + + + VL ELV Sbjct: 80 TLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELV 139 Query: 355 SKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGR 414 ++ +Q+D+ E CL+ I+LF+ D K L+N V+ +EK A+L Y YP + Sbjct: 140 LQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDK 199 Query: 415 FAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 459 F +LLL L +R++ ++ E+L+ L + P + L+EML+A Sbjct: 200 FQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQ 244 >4N1Y-A nrPDB Length = 240 Score = 184 bits (466), Expect = 9e-47, Method: Composition-based stats. Identities = 52/204 (25%), Positives = 100/204 (49%), Gaps = 2/204 (0%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 P + + ++ + A+++L L+ WAK +P +++L L DQV L+ W ELL+ + + Sbjct: 28 HGQPPTKVHLLNSLVKLAERELVHLINWAKNVPGYTDLSLSDQVHLIECCWMELLLLNCA 87 Query: 315 HRSIAVKDGIL-LATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAI 373 RSI L A L + R+S + + IF++V + +M + K EL L+A+ Sbjct: 88 FRSIEHGGKSLAFAPDLVLDRSSWSTVEMTEIFEQV-AAVSEQMMQNHLHKDELLLLQAM 146 Query: 374 VLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCL 433 VL N + + L++ ++ +++ + ++ + +P+ +LL L +R G + + Sbjct: 147 VLVNAEVRRLASYNQIFNMQQSLLDAIVDTAQKYHPDNVRHVPAVLLLLTHIRQAGERGI 206 Query: 434 EHLFFFKLIGDTPIDTFLMEMLEA 457 K G L EML+A Sbjct: 207 AFFQRLKSEGVVTFCDLLKEMLDA 230 >2H79-A nrPDB Length = 269 Score = 184 bits (466), Expect = 1e-46, Method: Composition-based stats. Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 2/194 (1%) Query: 264 PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDG 323 + + + +V++AK++P FSELP +DQ+ILL+ E++ + R D Sbjct: 73 AFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDT 132 Query: 324 ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL 383 + L+ + V R + G+G + D + EL + +D TE+ L+A++L + D GL Sbjct: 133 LTLSGEMAVKREQLKNGGLGVVSDAIF-ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGL 191 Query: 384 SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 443 ++E +E + E Y H+ P + KLL+++ LR IG K+ Sbjct: 192 LCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHCKVEC 251 Query: 444 DTPI-DTFLMEMLE 456 T + +E+ E Sbjct: 252 PTELFPPLFLEVFE 265 >3UVV-A nrPDB Length = 265 Score = 183 bits (465), Expect = 1e-46, Method: Composition-based stats. Identities = 51/214 (23%), Positives = 98/214 (45%), Gaps = 5/214 (2%) Query: 247 ETYVEANMGLNPSSPN---DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRA 303 E ++ M P + + + + +V++AK++P FSELP +DQ+ILL+ Sbjct: 49 EDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKG 108 Query: 304 GWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMD 363 E++ + R + + L+ + V R + G+G + D + +L + +D Sbjct: 109 CCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIF-DLGKSLSAFNLD 167 Query: 364 KTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLP 423 TE+ L+A++L + D GL ++E +E + E Y ++ P + KLL+++ Sbjct: 168 DTEVALLQAVLLMSSDRTGLICVDKIEKCQETYLLAFEHYINYRKHNIPHFWPKLLMKVT 227 Query: 424 ALRSIGLKCLEHLFFFKLIGDTPI-DTFLMEMLE 456 LR IG K+ T + +E+ E Sbjct: 228 DLRMIGACHASRFLHMKVECPTELFPPLFLEVFE 261 >1YJE-A nrPDB Length = 264 Score = 183 bits (465), Expect = 1e-46, Method: Composition-based stats. Identities = 60/236 (25%), Positives = 102/236 (43%), Gaps = 14/236 (5%) Query: 231 PVERILEAELAVEPKT-----ETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKR 285 + ++ A L P T + E + V L + +WA++ Sbjct: 30 LLTSLIRAHLDSGPNTAKLDYSKFQELVLPRFGKEDAGDVQQFYDLLSGSLDVIRKWAEK 89 Query: 286 IPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI 345 IP F EL DQ +LL + + EL I ++RS + ++ +GL +HR G G Sbjct: 90 IPGFIELSPGDQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCAR-GFGDW 148 Query: 346 FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK 405 D +L + + +D CL A+VL D GL +P VE L+ ++ + L+ + Sbjct: 149 IDNILA-FSRSLHSLGVDVPAFACLSALVLIT-DRHGLQDPRRVEELQNRIASCLKEHMA 206 Query: 406 HKY--PEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEML 455 P+ ++LL +LP LR++ + L+ +F KL P +D M+ L Sbjct: 207 AVAGDPQPASCLSRLLGKLPELRTLCTQGLQRIFCLKLEDLVPPPPIVDKIFMDTL 262 >5L7E-A nrPDB Length = 305 Score = 182 bits (462), Expect = 3e-46, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 10/207 (4%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S R Sbjct: 46 KPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWR 105 Query: 317 SIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374 S + + A L + H + + + + + ++ + +Q+ E ++ ++ Sbjct: 106 SYKHTNSQFLYFAPDLVFNEEKMHQSAMYEL-CQGMHQISLQFVRLQLTFEEYTIMKVLL 164 Query: 375 LFNPDSK-GLSNPAEVEALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGL 430 L + K GL + A E +R L + RF +L L ++ + Sbjct: 165 LLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKSPNNSGQSWQRFYQLTKLLDSMHDLVS 224 Query: 431 KCLEHLFFFKLIG---DTPIDTFLMEM 454 LE F+ L+E+ Sbjct: 225 DLLEFCFYTFRESHALKVEFPAMLVEI 251 >3VHU-A nrPDB Length = 294 Score = 181 bits (460), Expect = 5e-46, Method: Composition-based stats. Identities = 45/207 (21%), Positives = 89/207 (42%), Gaps = 10/207 (4%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S R Sbjct: 68 KPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWR 127 Query: 317 SIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374 S + + A L + H + + + + + ++ + +Q+ E ++ ++ Sbjct: 128 SYKHTNSQFLYFAPDLVFNEEKMHQSAMYEL-CQGMHQISLQFVRLQLTFEEYTIMKVLL 186 Query: 375 LFNPDSK-GLSNPAEVEALREKVYASLEAY---CKHKYPEQPGRFAKLLLRLPALRSIGL 430 L + K GL + A E +R L C + + RF +L L ++ + Sbjct: 187 LLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVS 246 Query: 431 KCLEHLFFFKLIG---DTPIDTFLMEM 454 LE F+ L+E+ Sbjct: 247 DLLEFCFYTFRESHALKVEFPAMLVEI 273 >2Q1H-A nrPDB Length = 250 Score = 180 bits (458), Expect = 7e-46, Method: Composition-based stats. Identities = 41/190 (21%), Positives = 86/190 (45%), Gaps = 7/190 (3%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 P + N ++++ + A KQ+ ++V+WAK +P F L LDDQ+ L++ W L+ S Sbjct: 22 NSQPDTTNYLLSSLNRLAGKQMVSVVKWAKALPGFRNLHLDDQMTLIQYSWMSLMAFSLG 81 Query: 315 HRSIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 RS +G + A L + + + + + + ++ + +Q+ E C++ Sbjct: 82 WRSYKHTNGQMLYFAPDLIFNEERMQQSAMYDL-CQGMRQISQEFVRLQVTYEEFLCMKV 140 Query: 373 IVLFNPDSK-GLSNPAEVEALREKVYASLEAYC---KHKYPEQPGRFAKLLLRLPALRSI 428 ++L + K GL + A + +R L ++ + RF +L L ++ + Sbjct: 141 LLLLSTVPKDGLKSQASFDEMRMNYIKELRRAIAKKENNSSQNWQRFYQLTKLLDSMHDL 200 Query: 429 GLKCLEHLFF 438 L+ F+ Sbjct: 201 VGGLLQFCFY 210 >2XYJ-A nrPDB Length = 288 Score = 180 bits (457), Expect = 1e-45, Method: Composition-based stats. Identities = 68/258 (26%), Positives = 111/258 (43%), Gaps = 19/258 (7%) Query: 212 GKDRNENEVESTSSANEDMP-----VERILEAELAVEPKTETYVEANMGLNPSSPNDP-V 265 + + T A+ P +E + +AE K + + GL P V Sbjct: 38 NMTKKKARSILTGKASHTAPFVIHDIETLWQAE-----KGLVWKQLVNGLPPYKEISVHV 92 Query: 266 TNICQAADKQLF-TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGI 324 CQ + L E+AK IP FS L L+DQV LL+ G +E + A + SI KDG+ Sbjct: 93 FYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLA--SIVNKDGL 150 Query: 325 LLATGLHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKG 382 L+A G + D E K +++D ++L A ++ D G Sbjct: 151 LVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPG 210 Query: 383 LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L N VEA+++ + +LE + + +P+ F KLL ++ LR + EH + I Sbjct: 211 LMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQL---VTEHAQMMQRI 267 Query: 443 GDTPIDTFLMEMLEAPHQ 460 T +T L +L+ ++ Sbjct: 268 KKTETETSLHPLLQEIYK 285 >1OT7-A nrPDB Length = 229 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 52/232 (22%), Positives = 100/232 (43%), Gaps = 7/232 (3%) Query: 225 SANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAK 284 + ++ ++ I+++ + + + + S + + + A + LVE+ K Sbjct: 4 TVDQQTLLDYIMDSY--SKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTK 61 Query: 285 RIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGA 344 R+P F L +DQ+ LL+ E + RS + + L A + +G+ Sbjct: 62 RLPGFQTLDHEDQIALLKGSAVEAMFL----RSAEIFNKKLPAGHADLLEERIRKSGISD 117 Query: 345 IFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYC 404 + + + +++M + E L AIV+ +PD + + + VE L+E + L+ C Sbjct: 118 EYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLC 177 Query: 405 KHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 456 K PE P FA LL RL LR+ E L +++ D L E+ + Sbjct: 178 KIYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRV-NDHKFTPLLCEIWD 228 >3ET1-A nrPDB Length = 291 Score = 179 bits (453), Expect = 3e-45, Method: Composition-based stats. Identities = 60/275 (21%), Positives = 104/275 (37%), Gaps = 40/275 (14%) Query: 221 ESTSSANEDMPVERILEAELAVEPKTETYVEANM-------------------------- 254 +A+ +RI EA L + + Sbjct: 19 SHMETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLV 78 Query: 255 ------GLNPSSPNDPVTNICQAADKQLFT-LVEWAKRIPHFSELPLDDQVILLRAGWNE 307 G+ + + CQ + T L E+AK IP F+ L L+DQV LL+ G E Sbjct: 79 AKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYE 138 Query: 308 LLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKT 365 + A S S+ KDG+L+A G + D + K +++D + Sbjct: 139 AIFAMLS--SVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDS 196 Query: 366 ELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPAL 425 ++ A ++ D GL N +E ++E + L + + +P+ F KLL ++ L Sbjct: 197 DISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADL 256 Query: 426 RSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQ 460 R + EH ++I T D L +L+ ++ Sbjct: 257 RQL---VTEHAQLVQIIKKTESDAALHPLLQEIYR 288 >1Y9R-A nrPDB Length = 255 Score = 179 bits (453), Expect = 3e-45, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 10/207 (4%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P + + ++ + + A KQ+ +V+WAK +P F LPL+DQ+ L++ W LL + S R Sbjct: 29 KPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLLSFALSWR 88 Query: 317 SIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374 S + + A L + H + + + + + ++ + +Q+ E ++ ++ Sbjct: 89 SYKHTNSQFLYFAPDLVFNEEKMHQSAMYEL-CQGMHQISLQFVRLQLTFEEYTIMKVLL 147 Query: 375 LFNPDSK-GLSNPAEVEALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGL 430 L + K GL + A E +R L + RF +L L ++ + Sbjct: 148 LLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKAPNNSGQSWQRFYQLTKLLDSMHDLVS 207 Query: 431 KCLEHLFFFKLIG---DTPIDTFLMEM 454 LE F+ L+E+ Sbjct: 208 DLLEFCFYTFRESHALKVEFPAMLVEI 234 >1YNW-B nrPDB Length = 99 Score = 178 bits (452), Expect = 4e-45, Method: Composition-based stats. Identities = 99/99 (100%), Positives = 99/99 (100%) Query: 130 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY Sbjct: 1 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 60 Query: 190 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE 228 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE Sbjct: 61 CRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANE 99 >3RY9-A nrPDB Length = 250 Score = 178 bits (451), Expect = 5e-45, Method: Composition-based stats. Identities = 44/206 (21%), Positives = 90/206 (43%), Gaps = 10/206 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + N ++++ + +Q+ + V+WAK +P F L LDDQ+ LL+ W L+ S RS Sbjct: 25 PDTTNRLLSSLNRLGGRQMISAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRS 84 Query: 318 IAVKDGIL--LATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVL 375 +G + A L + + + + + + ++ + +Q+ E C++ ++L Sbjct: 85 YQHTNGNMLYFAPDLIFNEERMQQSSMYEL-CKGMHKISLEFVRLQVSYEEYLCMKVLLL 143 Query: 376 FNPDSK-GLSNPAEVEALREKVYASL-EAYCKH--KYPEQPGRFAKLLLRLPALRSIGLK 431 + K GL + A + +R L +A K + RF +L L ++ + Sbjct: 144 LSTVPKDGLKSQAAFDEIRMSYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDLVGG 203 Query: 432 CLEHLFFFKLIGD---TPIDTFLMEM 454 L+ F+ + L+E+ Sbjct: 204 LLQFCFYTFVESKTLSVEFPEMLVEI 229 >5NFP-A nrPDB Length = 280 Score = 177 bits (450), Expect = 7e-45, Method: Composition-based stats. Identities = 49/207 (23%), Positives = 85/207 (41%), Gaps = 9/207 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L+ + RS Sbjct: 56 PDSTWRIMTTLNMLGGRQMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRS 115 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 LL + N + ++D+ + + S++ +Q+ E C++ ++L Sbjct: 116 YRQSSANLLCFAPDLIINE-QRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLL 174 Query: 376 FNPDSK-GLSNPAEVEALREKVYASL-EAYCKH--KYPEQPGRFAKLLLRLPALRSIGLK 431 + K GL + + +R L +A K + RF +L L ++ + Sbjct: 175 LSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVEN 234 Query: 432 CLEHLFFFKLIGDTPIDTFLMEMLEAP 458 L + F L I+ EML Sbjct: 235 LLNYCFQTFLDKTMSIE--FPEMLAEI 259 >4E2J-A nrPDB Length = 250 Score = 175 bits (445), Expect = 3e-44, Method: Composition-based stats. Identities = 46/207 (22%), Positives = 91/207 (43%), Gaps = 9/207 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P + ++ + + +Q+ + V+WAK +P F L LDDQ+ LL+ W L+ S RS Sbjct: 27 PDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRS 86 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 +G +L + N + ++D+ + ++ S+ +Q+ E C++ ++L Sbjct: 87 YKQSNGNMLCFAPDLVINE-ERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLL 145 Query: 376 FNPDSK-GLSNPAEVEALREKVYASL-EAYCKH--KYPEQPGRFAKLLLRLPALRSIGLK 431 + K GL + A + +R L +A K + RF +L L ++ + Sbjct: 146 LSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEMVGG 205 Query: 432 CLEHLFFFKLIGDTPIDTFLMEMLEAP 458 L+ F+ + ++ EML Sbjct: 206 LLQFCFYTFVNKSLSVE--FPEMLAEI 230 >3MNP-A nrPDB Length = 261 Score = 175 bits (444), Expect = 3e-44, Method: Composition-based stats. Identities = 47/207 (22%), Positives = 85/207 (41%), Gaps = 9/207 (4%) Query: 258 PSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRS 317 P S +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L++ + RS Sbjct: 37 PDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMVFALGWRS 96 Query: 318 IAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVL 375 G LL + N + ++D+ + + ++++ +Q+ E C++ ++L Sbjct: 97 YRQASGNLLCFAPDLIINE-QRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLL 155 Query: 376 FNPDSK-GLSNPAEVEALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGLK 431 + K GL + + +R L + RF +L L ++ + Sbjct: 156 LSSVPKEGLKSQELFDEIRMTYIKELGKAIAKRGGNSSQNWQRFYQLTKLLDSMHDVVEN 215 Query: 432 CLEHLFFFKLIGDTPIDTFLMEMLEAP 458 L + F L I+ EML Sbjct: 216 LLSYCFQTFLDKSMSIE--FPEMLAEI 240 >5UC1-A nrPDB Length = 222 Score = 175 bits (443), Expect = 5e-44, Method: Composition-based stats. Identities = 44/178 (24%), Positives = 80/178 (44%), Gaps = 7/178 (3%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 G P + +T + +Q+ V+WAK IP F L LDDQ+ LL+ W L+ + Sbjct: 30 GTVPDTTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALG 89 Query: 315 HRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRA 372 RS G +L + N G+ ++D+ + + S+++ +Q+ E C++ Sbjct: 90 WRSYRQSSGNVLCFAPDLIINE-QRMGLPYMYDQCKQMLFVSSELKRLQVSYEEYLCMKT 148 Query: 373 IVLFNPDSK-GLSNPAEVEALREKVYASL-EAYCKH--KYPEQPGRFAKLLLRLPALR 426 ++LF+ K GL + + +R L +A K + RF +L L ++ Sbjct: 149 LLLFSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMH 206 >4OZR-E nrPDB Length = 197 Score = 174 bits (442), Expect = 5e-44, Method: Composition-based stats. Identities = 57/216 (26%), Positives = 94/216 (43%), Gaps = 23/216 (10%) Query: 240 LAVEPKTETYVEANMGLNPSSPNDP-VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQV 298 ++ E + + P+D +I + + +VE+AKR+P F +L +DQ+ Sbjct: 3 ISPEQEELIHRLVYFQNEYEQPSDEDFRHITEITILTVQLIVEFAKRLPGFDKLLREDQI 62 Query: 299 ILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMR 358 LL+A +E+++ + R D IL A D +L +M Sbjct: 63 ALLKACSSEVMMLRMARRYDVGSDSIL------------------ATVDDLL-RFCRQMY 103 Query: 359 DMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKY-PEQPGRFAK 417 M++D E L AIV+F+ + L +VE ++E +L+ Y ++ P FAK Sbjct: 104 GMKVDNAEYALLTAIVIFS-ERPSLIEGWKVEKIQEIYLEALKVYVDNRRKPRSGTIFAK 162 Query: 418 LLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLME 453 LL L LR++G E F KL + FL E Sbjct: 163 LLSVLTELRTLGNLNSEMCFSLKLKNK-KLPPFLAE 197 >5GIE-A nrPDB Length = 256 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 93/200 (46%), Gaps = 7/200 (3%) Query: 260 SPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA 319 SP + ++ + ++ +AK IP F +L DDQ++LL++ E+++ S++S Sbjct: 55 SPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLR-SNQSFT 113 Query: 320 VKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFN 377 + D + + G + + L + ++ + + + E L AI + + Sbjct: 114 MDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVS 173 Query: 378 PDSKGLSNPAEVEALREKVYASLEAYCKHKY--PEQPGRFAKLLLRLPALRSIGLKCLE- 434 PD G+ + VEA+++++ +L+ Y + ++ P +AK++ +L LRS+ + + Sbjct: 174 PDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQ 233 Query: 435 -HLFFFKLIGDTPIDTFLME 453 F+ + ++E Sbjct: 234 YRSLSFQPENSMKLTPLVLE 253 >1RJK-A nrPDB Length = 292 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 93/200 (46%), Gaps = 7/200 (3%) Query: 260 SPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA 319 SP + ++ + ++ +AK IP F +L DDQ++LL++ E+++ S++S Sbjct: 56 SPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLR-SNQSFT 114 Query: 320 VKDGILLATGLHVHRNSAHSAGVGAIFDRV--LTELVSKMRDMQMDKTELGCLRAIVLFN 377 + D + + G + + L + ++ + + + E L AI + + Sbjct: 115 MDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVS 174 Query: 378 PDSKGLSNPAEVEALREKVYASLEAYCKHKY--PEQPGRFAKLLLRLPALRSIGLKCLE- 434 PD G+ + VEA+++++ +L+ Y + ++ P +AK++ +L LRS+ + + Sbjct: 175 PDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQ 234 Query: 435 -HLFFFKLIGDTPIDTFLME 453 F+ + ++E Sbjct: 235 YRSLSFQPENSMKLTPLVLE 254 >2IHQ-A nrPDB Length = 260 Score = 172 bits (437), Expect = 3e-43, Method: Composition-based stats. Identities = 50/209 (23%), Positives = 95/209 (45%), Gaps = 10/209 (4%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 P S ++++ + ++QL +V+WAK +P F L +DDQ+ +++ W L++ + R Sbjct: 34 QPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWR 93 Query: 317 SIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374 S + + A L + H + + + R + L + +Q+ E C++A++ Sbjct: 94 SFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEFGWLQITPQEFLCMKALL 152 Query: 375 LFNPD-SKGLSNPAEVEALREKVYASLEAY--CKHKYPEQ-PGRFAKLLLRLPALRSIGL 430 LF+ GL N + LR L+ CK K P RF +L L +++ I Sbjct: 153 LFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAR 212 Query: 431 KCLEHLFFFKLIGDTPIDTF-LMEMLEAP 458 + H F F L+ + + + EM+ Sbjct: 213 EL--HQFTFDLLIKSHMVSVDFPEMMAEI 239 >3N00-A nrPDB Length = 245 Score = 172 bits (436), Expect = 3e-43, Method: Composition-based stats. Identities = 52/187 (27%), Positives = 89/187 (47%), Gaps = 1/187 (0%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 G + + + + + + +VE+AK IP F +L DQV LL+AG E+L+ F+ Sbjct: 57 GRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFA 116 Query: 315 HRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374 ++ + + G+G + + + K+ + + + ELG A+V Sbjct: 117 SLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSA-MFDFSEKLNSLALTEEELGLFTAVV 175 Query: 375 LFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLE 434 L + D G+ N A VE L+E + +L A P + RF KLLL+LP LR++ E Sbjct: 176 LVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE 235 Query: 435 HLFFFKL 441 L F++ Sbjct: 236 KLLSFRV 242 >2HCD-A nrPDB Length = 302 Score = 170 bits (432), Expect = 8e-43, Method: Composition-based stats. Identities = 49/267 (18%), Positives = 114/267 (42%), Gaps = 8/267 (2%) Query: 191 RYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYV 250 R++ + G + + + ++ S S + V+ L + ++ Sbjct: 33 RFRPPVREGPVT---RSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSGS 89 Query: 251 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 310 + + S + ++ + ++ +AK IP F +L +DQ+ LL++ E+++ Sbjct: 90 PDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIM 149 Query: 311 ASFSHRSIAVKDGILLATGLH--VHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELG 368 S++S +++D G N AG L + ++ +++ + E Sbjct: 150 LR-SNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHV 208 Query: 369 CLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSI 428 L AI L +PD G+ + +EAL++++ L+AY + ++P +AK++ +L LRS+ Sbjct: 209 LLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSL 268 Query: 429 GLKCLE--HLFFFKLIGDTPIDTFLME 453 + + F+ + ++E Sbjct: 269 NEEHSKQYRSLSFQPEHSMQLTPLVLE 295 >3P8X-A nrPDB Length = 280 Score = 169 bits (427), Expect = 3e-42, Method: Composition-based stats. Identities = 41/230 (17%), Positives = 97/230 (42%), Gaps = 11/230 (4%) Query: 234 RILEAELAVEPKTETYVEANMGLNPSSPN----DPVTNICQAADKQLFTLVEWAKRIPHF 289 + + + + V N G + + ++ + ++ +AK IP F Sbjct: 45 KTYDPTYSDFCQFRPPVRVNDGGGSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGF 104 Query: 290 SELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHR--NSAHSAGVGAIFD 347 +L +DQ++LL++ E+++ S+ S + D + AG Sbjct: 105 RDLTSEDQIVLLKSSAIEVIMLR-SNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELI 163 Query: 348 RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHK 407 L + ++ + + + E L AI + +PD G+ + A +EA+++++ +L+ Y + + Sbjct: 164 EPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCR 223 Query: 408 Y--PEQPGRFAKLLLRLPALRSIGLKCLE--HLFFFKLIGDTPIDTFLME 453 + P +AK++ +L LRS+ + + F+ + ++E Sbjct: 224 HPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE 273 >4NUF-A nrPDB Length = 580 Score = 165 bits (418), Expect = 4e-41, Method: Composition-based stats. Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 12/199 (6%) Query: 269 CQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVK--DGILL 326 C+ A L V + + +P F LP DDQ LL W L + + ++ + + + Sbjct: 379 CREALDVLAKTVAFLRNLPSFCHLPHDDQRRLLECCWGPLFLLGLAQDAVTFEVAEAPVP 438 Query: 327 ATGLHVHRNSAHSAGVGAIFD----------RVLTELVSKMRDMQMDKTELGCLRAIVLF 376 + + A S GA + L + +++ E L+ +LF Sbjct: 439 SILKKILTTRASSGTQGAQPSDRPQPSLAAVQWLQRCLESFWSLELGPKEYAYLKGTILF 498 Query: 377 NPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHL 436 NPD GL + L+++ + +L + YP GR A++LL LR+I L L Sbjct: 499 NPDVPGLRASCHIAHLQQEAHWALCEVLEPWYPASQGRLARILLMASTLRNIPGTLLVDL 558 Query: 437 FFFKLIGDTPIDTFLMEML 455 FF ++GD I L +ML Sbjct: 559 FFRPIMGDVDITELLEDML 577 >1XVP-B nrPDB Length = 246 Score = 165 bits (417), Expect = 5e-41, Method: Composition-based stats. Identities = 48/213 (22%), Positives = 88/213 (41%), Gaps = 9/213 (4%) Query: 248 TYVEANMGLNPSSPNDPV----TNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRA 303 + P PV T+ + ++++ K +P F LP++DQ+ LL+ Sbjct: 35 PPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 94 Query: 304 GWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMD 363 E+ + ++ L L G F +L +R +Q+ Sbjct: 95 AAVEICHIVLNTTFC-LQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 153 Query: 364 KTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK--HKYPEQPGRFAKLLLR 421 + E L A+ LF+PD G++ E++ L+E++ +L++Y K + P +AKLL Sbjct: 154 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 213 Query: 422 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEM 454 L LRSI + + G + + L E+ Sbjct: 214 LAELRSINEAYGYQIQHIQ--GLSAMMPLLQEI 244 >3F5C-B nrPDB Length = 268 Score = 163 bits (414), Expect = 1e-40, Method: Composition-based stats. Identities = 60/266 (22%), Positives = 96/266 (36%), Gaps = 25/266 (9%) Query: 218 NEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLF 277 E S PV E + +A+ G+ +C+AA L Sbjct: 2 EEQPQQISVASGTPVSADQTPATPQEQPRAPWWDASPGVQRLITLKDPQVVCEAASAGLL 61 Query: 278 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATG-------- 329 + + K +P F LPLD Q++L+R+ W LL+ + + + + T Sbjct: 62 KTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPETNTTQEMLTT 121 Query: 330 -------------LHVHRNSAHSAGVGAIFDRVLTELVSKM----RDMQMDKTELGCLRA 372 + SA G + + + + +D E L+ Sbjct: 122 RRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNIDTKEYAYLKG 181 Query: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432 VLFNPD GL +E L+ + L + + E R A+L L LR I Sbjct: 182 TVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSALFLLRFINSDV 241 Query: 433 LEHLFFFKLIGDTPIDTFLMEMLEAP 458 + LFF +IG +D ++EML A Sbjct: 242 VTELFFRPIIGAVSMDDMMLEMLCAK 267 >3HVL-A nrPDB Length = 344 Score = 162 bits (411), Expect = 3e-40, Method: Composition-based stats. Identities = 49/199 (24%), Positives = 90/199 (45%), Gaps = 9/199 (4%) Query: 262 NDPVTNICQAADKQLFT---LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI 318 + + + AD + ++ +AK I +F +LP++DQ+ LL+ EL F+ Sbjct: 116 KEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFN 175 Query: 319 AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP 378 A G L + G + + + ++ +Q+ + E ++AI LF+P Sbjct: 176 AET-GTWECGRLSYCLEDT-AGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSP 233 Query: 379 DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGR--FAKLLLRLPALRSIGLKCLEHL 436 D G+ V+ L+E+ +L++Y + P+ R F K++ L LRSI + + L Sbjct: 234 DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRL 293 Query: 437 FFFKLIGDTPIDTFLMEML 455 + I P T LM+ L Sbjct: 294 LRIQDI--HPFATPLMQEL 310 >4CN5-A nrPDB Length = 87 Score = 160 bits (406), Expect = 8e-40, Method: Composition-based stats. Identities = 83/83 (100%), Positives = 83/83 (100%) Query: 130 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY Sbjct: 5 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 64 Query: 190 CRYQKCLAMGMKREAVQEERQRG 212 CRYQKCLAMGMKREAVQEERQRG Sbjct: 65 CRYQKCLAMGMKREAVQEERQRG 87 >1XLS-E nrPDB Length = 242 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 53/243 (21%), Positives = 96/243 (39%), Gaps = 16/243 (6%) Query: 225 SANEDMPVERILEAELA-VEPKTETYVE------ANMGLNPSSPNDPV----TNICQAAD 273 + + V+ +L A V P + +V+ M P P PV T+ Sbjct: 1 NQQQKELVQILLGAHTRHVGPLFDQFVQFRPPAYLFMHHRPFQPRGPVLPLLTHFADINT 60 Query: 274 KQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVH 333 + ++++ K +P F L ++DQ+ LL+ E+L S + + L Sbjct: 61 FMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTTFCLQTEN-FFCGPLCYK 119 Query: 334 RNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR 393 A AG F + ++ + + + E + A LF+PD G++ E++ L+ Sbjct: 120 MEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFSPDRPGVTQREEIDQLQ 179 Query: 394 EKVYASLEAYCKHKYPEQPGRF--AKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 451 E++ L + + RF AKL+ L LRSI L +L + + L Sbjct: 180 EEMALILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINNAYSYELQ--RLEELSAMTPLL 237 Query: 452 MEM 454 E+ Sbjct: 238 GEI 240 >3G8O-A nrPDB Length = 263 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 83/191 (43%), Gaps = 9/191 (4%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 P + + +T++ Q ++QL ++V+W+K +P F L +DDQ+ L++ W L++ Sbjct: 35 NTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLG 94 Query: 315 HRSIAVKDG--ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRA 372 RS G + A L ++ + ++ + ++ + +Q+ + E C++ Sbjct: 95 WRSYKHVSGQMLYFAPDLILNEQRMKESSFYSL-CLTMWQIPQEFVKLQVSQEEFLCMKV 153 Query: 373 IVLFNPDS-KGLSNPAEVEALREKVYASLEAYCKHKYP---EQPGRFAKLLLRLPALRSI 428 ++L N +GL + + E +R L + RF +L L L + Sbjct: 154 LLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDL 213 Query: 429 GLKCLEHLFFF 439 + HL+ Sbjct: 214 VKQL--HLYCL 222 >1S0X-A nrPDB Length = 270 Score = 160 bits (404), Expect = 2e-39, Method: Composition-based stats. Identities = 48/231 (20%), Positives = 93/231 (40%), Gaps = 11/231 (4%) Query: 215 RNENEVESTSSANEDM---PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQA 271 E+ ++ S ++ + E + + + E Sbjct: 19 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEE-----IENYQNKQREVMWQLCAIK 73 Query: 272 ADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLH 331 + + +VE+AKRI F EL +DQ++LL+AG E++ R+ ++ + G + Sbjct: 74 ITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKY 132 Query: 332 VHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA 391 + S G V E + M + + E+ A VL + D L ++E Sbjct: 133 ASPDVFKSLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEK 191 Query: 392 LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442 L++K+ +L+ + + E G KL+ ++ LR++ + E L FK I Sbjct: 192 LQQKIQLALQHVLQKNHRED-GILTKLICKVSTLRALCGRHTEKLMAFKAI 241 >5L0M-A nrPDB Length = 112 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 48/81 (59%), Positives = 64/81 (79%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + +C +CGD+ SG HYG+ +CE CKGFFKRTV+ + YTC +N++C IDK QR RC YCR Sbjct: 8 EELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCR 67 Query: 192 YQKCLAMGMKREAVQEERQRG 212 +QKCL++GMK EAV+ +R RG Sbjct: 68 FQKCLSVGMKLEAVRADRMRG 88 >4UMM-A nrPDB Length = 78 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 68/78 (87%), Positives = 75/78 (96%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 KH+C+ICGDR+SGKHYGVYSCEGCKGFFKRTVRKDLTY CR+ ++C+IDKRQRNRCQYCR Sbjct: 1 KHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACREERNCIIDKRQRNRCQYCR 60 Query: 192 YQKCLAMGMKREAVQEER 209 YQKCLA GMKREAVQEER Sbjct: 61 YQKCLACGMKREAVQEER 78 >4OLN-A nrPDB Length = 82 Score = 152 bits (383), Expect = 4e-37, Method: Composition-based stats. Identities = 40/82 (48%), Positives = 56/82 (68%) Query: 129 SFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQ 188 S K +C +CGD +SG HYGV+SCEGCK FFKR+++ + Y C +C IDK +R CQ Sbjct: 1 SKPKRLCQVCGDHASGFHYGVWSCEGCKAFFKRSIQGHVDYVCPATNNCTIDKHRRKSCQ 60 Query: 189 YCRYQKCLAMGMKREAVQEERQ 210 CR +KCL +GM + ++ER+ Sbjct: 61 ACRLRKCLEVGMTKGGQRKERR 82 >1R0O-B nrPDB Length = 109 Score = 151 bits (382), Expect = 6e-37, Method: Composition-based stats. Identities = 42/103 (40%), Positives = 59/103 (57%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + +C +CGDR+SG HY +CEGCKGFF+R+V K Y C+ + C +D R +CQ CR Sbjct: 6 EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECR 65 Query: 192 YQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVER 234 +KCLA+GM+ E V E Q R E + + P + Sbjct: 66 LKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQ 108 >1LO1-A nrPDB Length = 98 Score = 150 bits (379), Expect = 1e-36, Method: Composition-based stats. Identities = 43/96 (44%), Positives = 64/96 (66%), Gaps = 1/96 (1%) Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 K +C +CGD +SG HYGV SCE CK FFKRT++ ++ Y+C +C I KR+R CQ C Sbjct: 3 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 62 Query: 191 RYQKCLAMGMKREAVQEERQR-GKDRNENEVESTSS 225 R+ K L +GM +E V+ +R R G+ + + ++S +S Sbjct: 63 RFMKALKVGMLKEGVRLDRVRGGRQKYKRRLDSENS 98 >1N4H-A nrPDB Length = 259 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 44/204 (21%), Positives = 87/204 (42%), Gaps = 9/204 (4%) Query: 257 NPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316 S + +VE+AKRI F EL +DQ++LL++G E+++ Sbjct: 51 QSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRA 110 Query: 317 SIAVKDGILLAT---GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAI 373 + + +L G+ + + V FD + +Q+ + E+ + Sbjct: 111 FNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFD-----FAKNLCSLQLTEEEIALFSSA 165 Query: 374 VLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCL 433 VL +PD L P +V+ L+EK+Y +L+ + + + AKL+ ++P + ++ Sbjct: 166 VLISPDRAWLLEPRKVQKLQEKIYFALQHVIQKNHLDDET-LAKLIAKIPTITAVCNLHG 224 Query: 434 EHLFFFKLIGDTPIDTFLMEMLEA 457 E L FK ++T + + Sbjct: 225 EKLQVFKQSHPDIVNTLFPPLYKE 248 >5CBX-A nrPDB Length = 105 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 38/82 (46%), Positives = 48/82 (58%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 A IC +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 24 AGPPPKICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 83 Query: 188 QYCRYQKCLAMGMKREAVQEER 209 CR++KCL GM EA + ++ Sbjct: 84 PACRFRKCLQAGMNLEARKTKK 105 >5CBZ-A nrPDB Length = 105 Score = 148 bits (375), Expect = 3e-36, Method: Composition-based stats. Identities = 37/82 (45%), Positives = 47/82 (57%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 AS +C +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 24 ASPPSKVCLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 83 Query: 188 QYCRYQKCLAMGMKREAVQEER 209 CR +KCL GM A + ++ Sbjct: 84 PACRLRKCLQAGMNLGARKSKK 105 >4UMM-E nrPDB Length = 87 Score = 147 bits (372), Expect = 9e-36, Method: Composition-based stats. Identities = 40/84 (47%), Positives = 54/84 (64%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + +C +CGDR+SG HY +CEGCKGFF+R+V K+ Y C+ C +D R +CQ CR Sbjct: 4 EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECR 63 Query: 192 YQKCLAMGMKREAVQEERQRGKDR 215 +KCLA+GM+ E V E Q R Sbjct: 64 LKKCLAVGMRPECVVPENQCAMKR 87 >5CC0-A nrPDB Length = 85 Score = 147 bits (371), Expect = 1e-35, Method: Composition-based stats. Identities = 38/82 (46%), Positives = 48/82 (58%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 AS + +C ICGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 3 ASPPQKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 62 Query: 188 QYCRYQKCLAMGMKREAVQEER 209 CR +KCL GM A + ++ Sbjct: 63 PACRLRKCLQAGMTLGARKSKK 84 >2FF0-A nrPDB Length = 102 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 45/80 (56%), Positives = 61/80 (76%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192 +C +CGD+ SG HYG+ +CE CKGFFKRTV+ + YTC +++ C IDK QR RC +CR+ Sbjct: 2 ELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRF 61 Query: 193 QKCLAMGMKREAVQEERQRG 212 QKCL +GM+ EAV+ +R RG Sbjct: 62 QKCLTVGMRLEAVRADRMRG 81 >5EMP-A nrPDB Length = 94 Score = 146 bits (368), Expect = 2e-35, Method: Composition-based stats. Identities = 36/85 (42%), Positives = 47/85 (55%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 8 TGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 67 Query: 188 QYCRYQKCLAMGMKREAVQEERQRG 212 CRY+KCL GM EA + +++ Sbjct: 68 PACRYRKCLQAGMNLEARKTKKKIK 92 >3CBB-A nrPDB Length = 78 Score = 145 bits (367), Expect = 3e-35, Method: Composition-based stats. Identities = 47/76 (61%), Positives = 64/76 (84%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +CAICGDR++GKHYG SC+GCKGFF+R+VRK+ Y+CR ++ C++DK +RN+C+YCR + Sbjct: 2 LCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLK 61 Query: 194 KCLAMGMKREAVQEER 209 KC GMK+EAVQ ER Sbjct: 62 KCFRAGMKKEAVQNER 77 >4TNT-A nrPDB Length = 103 Score = 144 bits (364), Expect = 6e-35, Method: Composition-based stats. Identities = 37/76 (48%), Positives = 43/76 (56%) Query: 128 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC 187 +S IC +CGD +SG HYGV +C CK FFKR V Y C DC+IDK +R C Sbjct: 28 SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 87 Query: 188 QYCRYQKCLAMGMKRE 203 CR QKCL GM Sbjct: 88 PACRLQKCLQAGMNLG 103 >5NTQ-A nrPDB Length = 238 Score = 144 bits (363), Expect = 8e-35, Method: Composition-based stats. Identities = 43/192 (22%), Positives = 79/192 (41%), Gaps = 17/192 (8%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 G S + + + +VE+AKR+ F EL +DQ++LL+AG E+++ Sbjct: 46 GYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMC 105 Query: 315 HRSIAVKDGILLA---TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLR 371 A + G+ + R S + +IFD + + + E+ Sbjct: 106 RAYNADNRTVFFEGKYGGMELFRALGCSELISSIFD-----FSHSLSALHFSEDEIALYT 160 Query: 372 AIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLP---ALRSI 428 A+VL N GL +VE L+ + + + + + +L +LP LRS+ Sbjct: 161 ALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQS------ILAKLPPKGKLRSL 214 Query: 429 GLKCLEHLFFFK 440 + +E L F+ Sbjct: 215 CSQHVERLQIFQ 226 >1HRA-A nrPDB Length = 80 Score = 144 bits (363), Expect = 8e-35, Method: Composition-based stats. Identities = 42/73 (57%), Positives = 59/73 (80%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +C D+SSG HYGV +CEGCKGFF+R+++K++ YTC +K+C+I+K RNRCQYCR QK Sbjct: 8 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQK 67 Query: 195 CLAMGMKREAVQE 207 C +GM +E+V+ Sbjct: 68 CFEVGMSKESVRN 80 >4XAI-A nrPDB Length = 573 Score = 144 bits (363), Expect = 8e-35, Method: Composition-based stats. Identities = 65/222 (29%), Positives = 107/222 (48%), Gaps = 16/222 (7%) Query: 247 ETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWN 306 +T EA ++ + + IC++A + +F V+W + IP F+ LPL DQ++LL W Sbjct: 355 QTVDEALKDAQTNAAAEFPSAICESAAQLIFMNVQWVRSIPAFTCLPLSDQLLLLEESWL 414 Query: 307 ELLIASFSHRSIAVKDGILLATGLHVHRNSAHS--AGVGAIFDRVLTELVSKMRDMQMDK 364 +L + + + + D +L V + H A + + D E + K+ Q+D Sbjct: 415 DLFVLGAAQ-FLPLMDFSVLVEACGVLQQEPHRRDAFLKEVAD--FQETLKKISQFQLDA 471 Query: 365 TELGCLRAIVLFNPD----------SKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGR 414 E CLRAIVLF K + A++ +++ L + YP+QP R Sbjct: 472 HEFACLRAIVLFKTSFEKPSSSSNQEKTTTESAKISVIQDDAQMRLNKHVTTTYPKQPLR 531 Query: 415 FAKLLLRLPA-LRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455 F K+LL + + R+I + +E LFF K+I DTPI + M Sbjct: 532 FGKILLLVSSTFRTISGRTIEDLFFKKVIRDTPIVAIISNMY 573 >2NLL-B nrPDB Length = 103 Score = 143 bits (360), Expect = 2e-34, Method: Composition-based stats. Identities = 38/86 (44%), Positives = 60/86 (69%), Gaps = 2/86 (2%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLT--YTCRDNKDCLIDKRQRNRCQYC 190 +C +CGD+++G HY +CEGCKGFF+RT++K+L Y+C+ C+IDK RN+CQ C Sbjct: 2 ELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQEC 61 Query: 191 RYQKCLAMGMKREAVQEERQRGKDRN 216 R++KC+ +GM + V ++ +R R Sbjct: 62 RFKKCIYVGMATDLVLDDSKRLAKRK 87 >5NI5-A nrPDB Length = 288 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 43/192 (22%), Positives = 79/192 (41%), Gaps = 17/192 (8%) Query: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314 G S + + + +VE+AKR+ F EL +DQ++LL+AG E+++ Sbjct: 65 GYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMC 124 Query: 315 HRSIAVKDGILLA---TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLR 371 A + G+ + R S + +IFD + + + E+ Sbjct: 125 RAYNADNRTVFFEGKYGGMELFRALGCSELISSIFD-----FSHSLSALHFSEDEIALYT 179 Query: 372 AIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLP---ALRSI 428 A+VL N GL +VE L+ + + + + + +L +LP LRS+ Sbjct: 180 ALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQS------ILAKLPPKGKLRSL 233 Query: 429 GLKCLEHLFFFK 440 + +E L F+ Sbjct: 234 CSQHVERLQIFQ 245 >6CFN-A nrPDB Length = 90 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 36/80 (45%), Positives = 47/80 (58%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY Sbjct: 3 KLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRY 62 Query: 193 QKCLAMGMKREAVQEERQRG 212 +KCL GM EA + +++ Sbjct: 63 RKCLQAGMNLEARKTKKKIK 82 >1CIT-A nrPDB Length = 89 Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 49/80 (61%), Positives = 64/80 (80%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 CA+CGD +S +HYGV +CEGCKGFFKRTV+K Y C NKDC +DKR+RNRCQ+CR+QK Sbjct: 3 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKSAKYICLANKDCPVDKRRRNRCQFCRFQK 62 Query: 195 CLAMGMKREAVQEERQRGKD 214 CLA+GM +E V+ + +G+ Sbjct: 63 CLAVGMVKEVVRTDSLKGRR 82 >1LAT-A nrPDB Length = 82 Score = 142 bits (357), Expect = 5e-34, Method: Composition-based stats. Identities = 37/80 (46%), Positives = 48/80 (60%) Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 C +C D +SG HYGV +CEGCK FFKR V Y C+ C+IDK +R C C Sbjct: 3 PARPCLVCSDEASGCHYGVLTCEGCKAFFKRAVEGQHNYLCKYEGKCIIDKIRRKNCPAC 62 Query: 191 RYQKCLAMGMKREAVQEERQ 210 RY+KCL GM EA + +++ Sbjct: 63 RYRKCLQAGMNLEARKTKKK 82 >2EBL-A nrPDB Length = 89 Score = 140 bits (354), Expect = 9e-34, Method: Composition-based stats. Identities = 49/77 (63%), Positives = 63/77 (81%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD+SSGKHYG ++CEGCK FFKR+VR++LTYTCR N++C ID+ RN+CQYCR +K Sbjct: 10 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKK 69 Query: 195 CLAMGMKREAVQEERQR 211 CL +GM+REAVQ Sbjct: 70 CLKVGMRREAVQRGSGP 86 >1GLU-A nrPDB Length = 81 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 36/79 (45%), Positives = 45/79 (56%) Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C C Sbjct: 3 PARPCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 62 Query: 191 RYQKCLAMGMKREAVQEER 209 RY+KCL GM EA + ++ Sbjct: 63 RYRKCLQAGMNLEARKTKK 81 >1R4I-A nrPDB Length = 105 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 40/101 (39%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Query: 130 FTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189 + C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C Sbjct: 5 PPQKTCLICGDEASGAHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 64 Query: 190 CRYQKCLAMGMKREAV-QEERQRGKDRNENEVESTSSANED 229 CR +KC GM A ++ K + E E S S ED Sbjct: 65 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGENSSAGSPTED 105 >1A6Y-A nrPDB Length = 94 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 40/85 (47%), Positives = 63/85 (74%), Gaps = 1/85 (1%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTY-TCRDNKDCLIDKRQRNRCQYCRY 192 +C +CGD +SG HYGV +CEGCKGFF+R++++++ Y C N++C I + RNRCQ CR+ Sbjct: 9 LCKVCGDVASGFHYGVLACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 68 Query: 193 QKCLAMGMKREAVQEERQRGKDRNE 217 +KCL++GM R+AV+ R +++ Sbjct: 69 KKCLSVGMSRDAVRFGRIPKREKQR 93 >5KRB-B nrPDB Length = 84 Score = 138 bits (349), Expect = 3e-33, Method: Composition-based stats. Identities = 44/81 (54%), Positives = 60/81 (74%) Query: 132 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCR 191 + C ICGDR++G HYG+ SCEGCKGFFKR++ Y C +K+C++ ++QRNRCQYCR Sbjct: 1 QRTCLICGDRATGLHYGIISCEGCKGFFKRSISNKRVYRCSRDKNCVMSRKQRNRCQYCR 60 Query: 192 YQKCLAMGMKREAVQEERQRG 212 KCL MGM R+A++E+ G Sbjct: 61 LLKCLQMGMNRKAIREDGMPG 81 >2C7A-A nrPDB Length = 78 Score = 138 bits (348), Expect = 5e-33, Method: Composition-based stats. Identities = 33/78 (42%), Positives = 43/78 (55%) Query: 131 TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYC 190 + IC ICGD +SG HYGV +C CK FFKR + Y C DC++DK +R C C Sbjct: 1 PQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPAC 60 Query: 191 RYQKCLAMGMKREAVQEE 208 R +KC GM + + Sbjct: 61 RLRKCCQAGMVLGGRKFK 78 >1KB2-A nrPDB Length = 110 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 36/103 (34%), Positives = 59/103 (57%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192 IC +CGDR++G H+ +CEGCKGFF+R++++ +TC N DC I K R CQ CR Sbjct: 7 RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRL 66 Query: 193 QKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERI 235 ++C+ +GM +E + + + + R A +D ++ Sbjct: 67 KRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKL 109 >1GDC-A nrPDB Length = 72 Score = 137 bits (346), Expect = 9e-33, Method: Composition-based stats. Identities = 36/72 (50%), Positives = 43/72 (59%) Query: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193 +C +C D +SG HYGV +C CK FFKR V Y C DC+IDK +R C CRY+ Sbjct: 1 LCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYR 60 Query: 194 KCLAMGMKREAV 205 KCL GM EA Sbjct: 61 KCLQAGMNLEAR 72 >2NLL-A nrPDB Length = 66 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 66/66 (100%), Positives = 66/66 (100%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK Sbjct: 1 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 60 Query: 195 CLAMGM 200 CLAMGM Sbjct: 61 CLAMGM 66 >4AA6-A nrPDB Length = 71 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 35/70 (50%), Positives = 45/70 (64%) Query: 133 HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRY 192 CA+C D +SG HYGV+SCEGCK FFKR+++ Y C C IDK +R CQ CR Sbjct: 2 RYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRL 61 Query: 193 QKCLAMGMKR 202 +KC +GM + Sbjct: 62 RKCYEVGMMK 71 >2ENV-A nrPDB Length = 88 Score = 131 bits (329), Expect = 8e-31, Method: Composition-based stats. Identities = 41/77 (53%), Positives = 56/77 (72%), Gaps = 1/77 (1%) Query: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194 C +CGD++SG HYGV++CEGCKGFF+RT+R L Y + + C I K+ RN+CQYCR+QK Sbjct: 10 CRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYE-KCERSCKIQKKNRNKCQYCRFQK 68 Query: 195 CLAMGMKREAVQEERQR 211 CLA+GM A++ Sbjct: 69 CLALGMSHNAIRFGSGP 85 >3UP0-A nrPDB Length = 243 Score = 57.7 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 43/202 (21%), Positives = 73/202 (36%), Gaps = 23/202 (11%) Query: 243 EPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLR 302 +P + + N SP D + D + V+ AKR+P F++L D + LL+ Sbjct: 25 DPMEQGRQATSFLKNEKSPADIMN----IMDVTMRRFVKMAKRLPAFNDLSQDGKFALLK 80 Query: 303 AGWNELLIASFSHRSIAVKDG---ILLATGLHVHRNSAHS--AGVGAIFDRVLTELVSKM 357 G E+L R + L V N A V + + Sbjct: 81 GGMIEMLTVRGVRRFDSSSGSWTTPTLGESSEVSINMFDQLNADVRSEQKMRFLQFFKIF 140 Query: 358 RDMQMDKTELG--CLRAIVLFNPDSKGLSNPAE---VEALREKVYASLEAYCKHKYPEQP 412 + + +L + IVLF+P +++P + + E+ A L Y + Y + Sbjct: 141 HE-DIRSNDLVISMIMLIVLFSP-RDSITDPEDRRIIARHHEQFSALLNRYLESLYGDDA 198 Query: 413 GRFAKLLLRLPA----LRSIGL 430 +L +LP LR I Sbjct: 199 H---QLNEQLPTALRMLREISA 217 >3ODW-A nrPDB Length = 536 Score = 34.2 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Query: 25 RGSMAAPSLHPSLG-PGIGSPGQLHSPISTLSSPIN--GMGPPFSV-ISSPMGP---HSM 77 +G + PS ++G PG +PG P+S L SP G P + SSP GP S+ Sbjct: 66 KGGVGMPSRDRNIGAPGQDTPGVSLHPLS-LDSPDREPGADAPLELGDSSPQGPMSLESL 124 Query: 78 SVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKP 109 + P + G T SP+ P S +++P Sbjct: 125 APPESTDEGAETESPEPGDEGEPGRSGLELEP 156 >3J7R-j nrPDB Length = 86 Score = 31.9 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 29/79 (36%), Gaps = 2/79 (2%) Query: 125 GNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQR 184 G + T +C CG ++ H +C C KR + + + + + + Sbjct: 8 GKRRNKTHTLCRRCGSKA--YHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRH 65 Query: 185 NRCQYCRYQKCLAMGMKRE 203 + Y R++ G+ + Sbjct: 66 LKIVYRRFRHGFREGITPK 84 >5LZY-j nrPDB Length = 97 Score = 31.9 bits (71), Expect = 0.70, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 29/82 (35%), Gaps = 2/82 (2%) Query: 125 GNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQR 184 G + T +C CG ++ H +C C KR + + + + + + Sbjct: 9 GKRRNKTHTLCRRCGSKA--YHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRH 66 Query: 185 NRCQYCRYQKCLAMGMKREAVQ 206 + Y R++ G + + Sbjct: 67 LKIVYRRFRHGFREGTTPKPKR 88 >1JRP-B nrPDB Length = 777 Score = 31.5 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 291 ELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHS--------AGV 342 +L D V L R GW+ L R++ DG L + + + G Sbjct: 285 KLLGADFVHLARCGWSADLSLPVCDRAMLHADGSYFVPALRIESHRLRTNTQSNTAFRGF 344 Query: 343 GAI-----FDRVLTELVSKMRDMQMDKTELGCLRAIVLFN-PDSKGLSNP 386 G +R + L M D E LRA+ ++ P+ GLS P Sbjct: 345 GGPQGALGMERAIEHLARGMGR---DPAE---LRALNFYDPPERGGLSAP 388 >4V6U-Bk nrPDB Length = 339 Score = 30.3 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 27/71 (38%), Gaps = 5/71 (7%) Query: 347 DRVLTELVSKMRDMQMDKTELGC-LRAI----VLFNPDSKGLSNPAEVEALREKVYASLE 401 + + EL + + + + E+G L A+ +++ PD + + L++ + Sbjct: 167 EEITPELANILNALGIQPLEVGLDLLAVYEDGIIYTPDVLAIDESEYINMLQKAYMHAFN 226 Query: 402 AYCKHKYPEQP 412 YP Sbjct: 227 LAVNIAYPTPQ 237 >2KWQ-A nrPDB Length = 92 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 15/70 (21%) Query: 149 VYSCEGCK-GFFK---RTVRKDLTY----------TCRDNKDCL-IDKRQRNRCQYCRYQ 193 V +C+ CK FK V ++ + C + +D+ + C C Sbjct: 15 VVTCKTCKYTHFKPKETCVSENHDFHWHNGVKRFFKCPCGNRTISLDRLPKKHCSTCGLF 74 Query: 194 KCLAMGMKRE 203 K +GM +E Sbjct: 75 KWERVGMLKE 84 >3KYD-B nrPDB Length = 551 Score = 29.6 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 26/74 (35%), Gaps = 5/74 (6%) Query: 233 ERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRI---PH- 288 ++ E A + + + P+ + D + + EWAK P Sbjct: 196 NQLFGEEDADQEVSPDRADPEAAWEPTEAEARARACNEDGDIKRISTKEWAKSTGYDPVK 255 Query: 289 -FSELPLDDQVILL 301 F++L DD LL Sbjct: 256 LFTKLFKDDIRYLL 269 >3KYC-B nrPDB Length = 660 Score = 29.6 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 26/74 (35%), Gaps = 5/74 (6%) Query: 233 ERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRI---PH- 288 ++ E A + + + P+ + D + + EWAK P Sbjct: 214 NQLFGEEDADQEVSPDRADPEAAWEPTEAEARARACNEDGDIKRISTKEWAKSTGYDPVK 273 Query: 289 -FSELPLDDQVILL 301 F++L DD LL Sbjct: 274 LFTKLFKDDIRYLL 287 >5U1D-X nrPDB Length = 88 Score = 29.6 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 196 LAMGMKREA-VQEE-RQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEAN 253 + +G + A V++E +RG++ E + + L E+A Sbjct: 15 MRVGPRTYADVRDEINKRGREDREAARTAVHDPERPLLRSPGLLPEIAPNASLGVVHRRT 74 Query: 254 MGLNPSSPNDPVT 266 G SP +PVT Sbjct: 75 GGTVTDSPRNPVT 87 >3TR6-A nrPDB Length = 225 Score = 29.6 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 382 GLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRL 422 L P + LRE+ S Y PEQ A LL++L Sbjct: 23 SLREPPLLAELREETTRSFSTYAMQTAPEQAQLLA-LLVKL 62 >3A1Y-G nrPDB Length = 284 Score = 28.8 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 26/63 (41%), Gaps = 5/63 (7%) Query: 352 ELVSKMRDMQMDKTELGC-LRAI----VLFNPDSKGLSNPAEVEALREKVYASLEAYCKH 406 EL + + + + E+G + A+ +++ PD + ++ L++ + Sbjct: 172 ELANILNALGIQPLEVGLDVLAVYEDGIVYTPDVLAIDEQEYIDMLQKAYMHAFNLAVNI 231 Query: 407 KYP 409 YP Sbjct: 232 AYP 234 >5W9Q-A nrPDB Length = 60 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 152 CEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKR 202 C C +R + C K ++++ Q CR+++CL MKR Sbjct: 10 CGACAACLRRMDCGRCDFCCDKPKFGGSNQKR----QKCRWRQCLQFAMKR 56 >5GAP-F nrPDB Length = 494 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 15/35 (42%) Query: 355 SKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389 K ++ + R + L +PD LS A++ Sbjct: 39 EKFNPFEILPESIELFRTLALISPDRLSLSETAQI 73 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.142 0.422 Lambda K H 0.267 0.0435 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,464,907 Number of Sequences: 36641 Number of extensions: 872668 Number of successful extensions: 2586 Number of sequences better than 10.0: 146 Number of HSP's better than 10.0 without gapping: 259 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 2061 Number of HSP's gapped (non-prelim): 306 length of query: 462 length of database: 10,336,785 effective HSP length: 100 effective length of query: 362 effective length of database: 6,672,685 effective search space: 2415511970 effective search space used: 2415511970 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)