BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P19623 (302 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2O06-A nrPDB 631 0.0 2B2C-A nrPDB 353 6e-98 1XJ5-A nrPDB 321 2e-88 4YUX-A nrPDB 265 2e-71 2PT6-A nrPDB 252 1e-67 1IY9-A nrPDB 202 1e-52 1INL-A nrPDB 202 2e-52 3O4F-A nrPDB 196 9e-51 1MJF-A nrPDB 172 1e-43 6QMM-B nrPDB 167 4e-42 1UIR-A nrPDB 149 2e-36 6BQ5-A nrPDB 137 5e-33 2ZSU-A nrPDB 129 2e-30 2CMG-A nrPDB 52 2e-07 3C6K-A nrPDB 40 8e-04 5WY0-A nrPDB 31 0.54 4X4W-A nrPDB 31 0.64 1X14-A nrPDB 30 1.2 4C7Y-A nrPDB 28 3.7 6CMZ-A nrPDB 27 8.9 5OBV-A nrPDB 27 9.5 >2O06-A nrPDB Length = 304 Score = 631 bits (1627), Expect = 0.0, Method: Compositional matrix adjust. Identities = 302/302 (100%), Positives = 302/302 (100%) Query: 1 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 60 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG Sbjct: 3 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 62 Query: 61 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 120 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV Sbjct: 63 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 122 Query: 121 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 180 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP Sbjct: 123 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 182 Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 240 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT Sbjct: 183 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 242 Query: 241 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND Sbjct: 243 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 302 Query: 301 VS 302 VS Sbjct: 303 VS 304 >2B2C-A nrPDB Length = 314 Score = 353 bits (906), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 225/293 (76%) Query: 6 DGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVL 65 +G + P + + +E WPGQA SLQV+++L H +S+YQD+LVF S TYGNVLVL Sbjct: 21 NGASDEEPTKVLKSDGQEMGGAWPGQAFSLQVKKVLFHEKSKYQDVLVFESTTYGNVLVL 80 Query: 66 DGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEI 125 DG++Q TERDEFSYQEM+A+LP+ +HP+P++VLIIGGGDGG+LREV+KH SVE V CEI Sbjct: 81 DGIVQATERDEFSYQEMLAHLPMFAHPDPKRVLIIGGGDGGILREVLKHESVEKVTMCEI 140 Query: 126 DEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLF 185 DE VI V+KKFLPGM+ G+S KL L GDGFEF+K +++ FDVIITDSSDP+GPAESLF Sbjct: 141 DEMVIDVAKKFLPGMSCGFSHPKLDLFCGDGFEFLKNHKNEFDVIITDSSDPVGPAESLF 200 Query: 186 KESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQ 245 +SYY+L++ ALKEDG+L QGE WLHL LI + F + +FP V YA + TYPSG Sbjct: 201 GQSYYELLRDALKEDGILSSQGESVWLHLPLIAHLVAFNRKIFPAVTYAQSIVSTYPSGS 260 Query: 246 IGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 +G+++C+KN + + P + LT +Q+ + L++YNS+VH+AAFVLP+F + AL Sbjct: 261 MGYLICAKNANRDVTTPARTLTAEQIKALNLRFYNSEVHKAAFVLPQFVKNAL 313 >1XJ5-A nrPDB Length = 334 Score = 321 bits (823), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 148/284 (52%), Positives = 208/284 (73%), Gaps = 4/284 (1%) Query: 19 GWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFS 78 GWF E +WPG+A SL+VE++L +S YQD++VF+S TYG VLVLDGVIQ TERDE + Sbjct: 46 GWFSEMSPMWPGEAHSLKVEKVLFQGKSDYQDVIVFQSATYGKVLVLDGVIQLTERDECA 105 Query: 79 YQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLP 138 YQEMI +LPLCS PNP+KVL+IGGGDGGVLREV +H S+E + CEID+ V+ VSK+F P Sbjct: 106 YQEMITHLPLCSIPNPKKVLVIGGGDGGVLREVARHASIEQIDMCEIDKMVVDVSKQFFP 165 Query: 139 GMAIGYSSSKLTLHVGDGFEFMKQNQD-AFDVIITDSSDPMGPAESLFKESYYQLMKTAL 197 +AIGY ++ L +GDG F+K + ++D +I DSSDP+GPA+ LF++ ++Q + AL Sbjct: 166 DVAIGYEDPRVNLVIGDGVAFLKNAAEGSYDAVIVDSSDPIGPAKELFEKPFFQSVARAL 225 Query: 198 KEDGVLCCQGECQWLHLDLIKEMRQFCQSLFP-VVAYAYCTIPTYPSGQIGFMLCS-KNP 255 + GV+C Q E WLH+D+I+++ C+ +F V YA+ ++PTYPSG IGFMLCS + P Sbjct: 226 RPGGVVCTQAESLWLHMDIIEDIVSNCREIFKGSVNYAWTSVPTYPSGVIGFMLCSTEGP 285 Query: 256 STNFQEPVQPLTQQQV-AQMQLKYYNSDVHRAAFVLPEFARKAL 298 +F+ P+ P+ + + LK+YN+++H AAF LP FA+K + Sbjct: 286 DVDFKHPLNPIDESSSKSNGPLKFYNAEIHSAAFCLPSFAKKVI 329 >4YUX-A nrPDB Length = 304 Score = 265 bits (677), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 130/293 (44%), Positives = 191/293 (65%), Gaps = 6/293 (2%) Query: 12 GPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKT---YGNVLVLDGV 68 G I GWFRE WPGQA+SL+VE++L+ +++Q + +F S +G V+ LDG Sbjct: 11 GSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGC 70 Query: 69 IQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDED 128 IQ T+ DEF Y E++ + LCSHP P +VLIIGGGDGGVLREV++H +VE +ID + Sbjct: 71 IQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGE 130 Query: 129 VIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQD-AFDVIITDSSDPMGPAESLFKE 187 V++ SK+ P ++ + + T+ VGDG F++Q D +DV+I D++DP GPA LF E Sbjct: 131 VMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGE 190 Query: 188 SYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFC-QSLFPVVAYAYCTIPTYPSGQI 246 ++Y+ + LK DG+ C QGE WL L+LI++M +F ++ F V YA +PTYP G I Sbjct: 191 AFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSI 250 Query: 247 GFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 G ++CSK + +P++P+ A+ LKYY+S++H+A+F LP FAR N Sbjct: 251 GTLVCSKKAGVDVTKPLRPVEDMPFAK-DLKYYDSEMHKASFALPRFARHINN 302 >2PT6-A nrPDB Length = 321 Score = 252 bits (644), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 128/282 (45%), Positives = 189/282 (67%), Gaps = 3/282 (1%) Query: 20 WFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSY 79 WF E +WPGQA SL+++++L+ +S+YQ++LVF S TYG VLVLDGVIQ TE+DEF+Y Sbjct: 43 WFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAY 102 Query: 80 QEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPG 139 EM+ ++P+ P+ VL++GGGDGG++RE+ K+ SVE++ CEIDE VI+VSK + Sbjct: 103 HEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKN 162 Query: 140 MAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKE 199 ++ GY ++ + + D +F++ + +DVII DSSDP+GPAE+LF +++Y+ + ALK Sbjct: 163 ISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKP 222 Query: 200 DGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNF 259 +G Q E W+H+ IK M + + LF V YA +IPTYP G IG + CSK T Sbjct: 223 NGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSK-TDTGL 281 Query: 260 QEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDV 301 +P + L ++ A LKYYN + H AAF LP F K + ++ Sbjct: 282 TKPNKKLESKEFA--DLKYYNYENHSAAFKLPAFLLKEIENI 321 >1IY9-A nrPDB Length = 275 Score = 202 bits (514), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 106/277 (38%), Positives = 175/277 (63%), Gaps = 8/277 (2%) Query: 18 EGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEF 77 E W+ E + G ++++V + LH ++ +Q + + ++ +GN+L LDG++ +E+DEF Sbjct: 2 ELWYTEKQTKNFG--ITMKVNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDEF 59 Query: 78 SYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFL 137 Y EM+A++PL +HPNP VL++GGGDGGV+RE++KHPSV+ +ID VI+ SKKFL Sbjct: 60 VYHEMVAHVPLFTHPNPEHVLVVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKFL 119 Query: 138 PGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTAL 197 P +A ++ + V DGF + ++++ +DVI+ DS++P+GPA +LF + +Y + AL Sbjct: 120 PSIAGKLDDPRVDVQVDDGFMHIAKSENQYDVIMVDSTEPVGPAVNLFTKGFYAGIAKAL 179 Query: 198 KEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPST 257 KEDG+ Q + W +LI +++ + +FP+ IPTYPSG F + SK Sbjct: 180 KEDGIFVAQTDNPWFTPELITNVQRDVKEIFPITKLYTANIPTYPSGLWTFTIGSKK--- 236 Query: 258 NFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFA 294 +P+ + + ++ KYY D+H+AAFVLP+F Sbjct: 237 --YDPLA-VEDSRFFDIETKYYTKDIHKAAFVLPKFV 270 >1INL-A nrPDB Length = 296 Score = 202 bits (513), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 103/270 (38%), Positives = 159/270 (58%), Gaps = 8/270 (2%) Query: 32 ALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSH 91 L +++ ++++ +S Q I +F + G V LDG+ TE+DEF Y EM+A++P+ H Sbjct: 29 GLFMKMNRVIYSGQSDIQRIDIFENPDLGVVFALDGITMTTEKDEFMYHEMLAHVPMFLH 88 Query: 92 PNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTL 151 PNP+KVLIIGGGDGG LREV+KH SVE + CE+D VI+ ++K+L + G+ + + Sbjct: 89 PNPKKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARKYLKQTSCGFDDPRAEI 148 Query: 152 HVGDGFEFMKQNQDAFDVIITDSSDPM-GPAESLFKESYYQLMKTALKEDGVLCCQGECQ 210 + +G E++++ ++ FDVII DS+DP G LF E +YQ ALKEDGV + E Sbjct: 149 VIANGAEYVRKFKNEFDVIIIDSTDPTAGQGGHLFTEEFYQACYDALKEDGVFSAETEDP 208 Query: 211 WLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQ 270 + + K + +FP+ + TYPSG + SK +P++ ++ Sbjct: 209 FYDIGWFKLAYRRISKVFPITRVYLGFMTTYPSGMWSYTFASKGI-----DPIKDFDPEK 263 Query: 271 VAQM--QLKYYNSDVHRAAFVLPEFARKAL 298 V + +LKYYN +VH A+F LP F +K L Sbjct: 264 VRKFNKELKYYNEEVHVASFALPNFVKKEL 293 >3O4F-A nrPDB Length = 294 Score = 196 bits (499), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 104/286 (36%), Positives = 159/286 (55%), Gaps = 6/286 (2%) Query: 15 AIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTER 74 A ++ W ET GQ + V+ +L+H ++ +QD+++F + +G V+ LDGV+Q TER Sbjct: 8 AEKKQW-HETLHDQFGQYFA--VDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTER 64 Query: 75 DEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSK 134 DEF Y EM+ ++PL +H + + VLIIGGGDG +LREV +H +VES+ EID V+ + Sbjct: 65 DEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCR 124 Query: 135 KFLPGMAIG-YSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLM 193 ++LP G Y + L + DG F+ Q FDVII+D +DP+GP ESLF ++Y+ Sbjct: 125 QYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGC 184 Query: 194 KTALKEDGVLCCQ-GECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCS 252 K L G+ Q G C + I R+ F V + IPTY G + F + Sbjct: 185 KRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSH-YFSDVGFYQAAIPTYYGGIMTFAWAT 243 Query: 253 KNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 N + + + ++ +YYN +H AAF LP++ + AL Sbjct: 244 DNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDAL 289 >1MJF-A nrPDB Length = 281 Score = 172 bits (437), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 101/293 (34%), Positives = 163/293 (55%), Gaps = 33/293 (11%) Query: 22 RETCSLWP-GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQ 80 R +P G ++ ++++ ++ + S+YQ I V+ ++ +G +L LDG +Q E SY Sbjct: 3 RAFIEWYPRGYGVAFKIKKKIYEKLSKYQKIEVYETEGFGRLLALDGTVQLVTLGERSYH 62 Query: 81 EMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKK----- 135 E + + + +HP P++VL+IGGGDGG +REV++H V+ V+ EIDEDVI VSK Sbjct: 63 EPLVHPAMLAHPKPKRVLVIGGGDGGTVREVLQH-DVDEVIMVEIDEDVIMVSKDLIKID 121 Query: 136 --FLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLM 193 L M G K L +GDGFEF+K N+ FDVII DS+DP+GPA+ LF E +Y+ + Sbjct: 122 NGLLEAMLNG-KHEKAKLTIGDGFEFIKNNR-GFDVIIADSTDPVGPAKVLFSEEFYRYV 179 Query: 194 KTALKEDGVLCCQGECQWLHLDLI----KEMRQFCQSL----FPVVAYAYCTIPTYPSGQ 245 AL G+ Q +L D + KEM++ + FPV+ YA Sbjct: 180 YDALNNPGIYVTQAGSVYLFTDELISAYKEMKKVFDRVYYYSFPVIGYA---------SP 230 Query: 246 IGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 F++ K +F + + +++ ++QL+YY+ +H F +P++ R+ L Sbjct: 231 WAFLVGVKG-DIDFTK----IDRERAKKLQLEYYDPLMHETLFQMPKYIRETL 278 >6QMM-B nrPDB Length = 280 Score = 167 bits (424), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 91/262 (34%), Positives = 142/262 (54%), Gaps = 4/262 (1%) Query: 39 QLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVL 98 Q+L S +Q I + ++ YG L+LD ER E Y E + + PL + + +VL Sbjct: 19 QILWEETSPFQKITIVDTEHYGRGLLLDDCWMTAERCEVCYHEYLVHPPLTTAASIARVL 78 Query: 99 IIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFE 158 +IGGGDGG +REV+++ VE V EID V+++S+++L + ++ +L + +GDG Sbjct: 79 VIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYLGAIGTAWADPRLNVKIGDGIA 138 Query: 159 FMKQNQDA-FDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLI 217 F++ DA +DVI+ D SDP GPA LF +Y+ + LK GV Q E L + Sbjct: 139 FVQTAPDASYDVILVDGSDPAGPAAGLFNREFYENCRRVLKPGGVFASQAESPDSFLAVH 198 Query: 218 KEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLK 277 EM + ++F Y +P YPSG ++ S P FQ+P + + Q++ Sbjct: 199 LEMIETLSAVFAEAKPYYGWVPMYPSGWWSWLYASDTPG-QFQKPQS--DRLAAIEPQVE 255 Query: 278 YYNSDVHRAAFVLPEFARKALN 299 YN D+H+AAF P F R+ L+ Sbjct: 256 IYNRDIHQAAFAQPNFVRRGLS 277 >1UIR-A nrPDB Length = 314 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 87/287 (30%), Positives = 159/287 (55%), Gaps = 12/287 (4%) Query: 20 WFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSY 79 +F E + P + L ++E+++ ++ +QD +F SK +G VL+LD +Q TERDE+ Y Sbjct: 6 YFFEHVT--PYETLVRRMERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEYIY 63 Query: 80 QEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPG 139 E + + + +HP P++VLI+GGG+G LREV+KHP+VE V +ID ++++V+K+ +P Sbjct: 64 HETLVHPAMLTHPEPKRVLIVGGGEGATLREVLKHPTVEKAVMVDIDGELVEVAKRHMPE 123 Query: 140 MAIG-YSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMG---PAESLFKESYYQLMKT 195 G + + L + D ++++ ++ +DV+I D +DP+G PA L+ +Y+L+K Sbjct: 124 WHQGAFDDPRAVLVIDDARAYLERTEERYDVVIIDLTDPVGEDNPARLLYTVEFYRLVKA 183 Query: 196 ALKEDGVLCCQ-GECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSK- 253 L GV+ Q G H + + + + F V IP + GF+L S Sbjct: 184 HLNPGGVMGMQTGMILLTHHRVHPVVHRTVREAFRYVRSYKNHIPGF-FLNFGFLLASDA 242 Query: 254 -NPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 +P+ + ++ +++ + L++ + A FVLP+ +AL Sbjct: 243 FDPAAFSEGVIEARIRER--NLALRHLTAPYLEAMFVLPKDLLEALE 287 >6BQ5-A nrPDB Length = 331 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 79/271 (29%), Positives = 145/271 (53%), Gaps = 7/271 (2%) Query: 35 LQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNP 94 + +LH S+YQDI + +K +G LVLDG +Q E DEF Y E + + L HP P Sbjct: 43 FALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMP 102 Query: 95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 + V I+GGG+G RE+++H +++ VV C+IDE+V++ K +L + S+L + + Sbjct: 103 KNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVIN 162 Query: 155 DGFEFMKQNQDAFDVIITDSSDPM--GPAESLFKESYYQL-MKTALKEDGVLCCQGECQW 211 D ++ ++ +DVI+ D +DP+ GP L+ + +Y+L +K LK+ G+ Q Sbjct: 163 DAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAG 222 Query: 212 L--HLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQ 269 + H ++ + + +F V IP+Y + G++L S +P E + +Q Sbjct: 223 IFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSY-ADIWGWVLASDSPLDLSAEELDIRMRQ 281 Query: 270 QVAQMQLKYYNSDVHRAAFVLPEFARKALND 300 ++ + + +Y + ++ L + R +LN+ Sbjct: 282 RIIE-ENRYLDGKTFVSSSTLSKAVRNSLNN 311 >2ZSU-A nrPDB Length = 280 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 99/292 (33%), Positives = 160/292 (54%), Gaps = 32/292 (10%) Query: 23 ETCSLWP-GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQE 81 E +P G ++ +V++ + +S YQ I V+ ++ +G +L +DG +Q E SY E Sbjct: 5 EFIEWYPRGYGVAFKVKRKILEEQSEYQKIEVYETEGFGKLLAIDGTVQLVTEGEKSYHE 64 Query: 82 MIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMA 141 + + + +HPNPR+VLIIGGGDGG +REV+KH VE V+ EID+ VI++S K++ G+ Sbjct: 65 PLVHPAMLAHPNPRRVLIIGGGDGGAIREVLKHEEVEEVIMVEIDKKVIEISAKYI-GID 123 Query: 142 IGYSSSKLT-------LHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMK 194 G L+ L +GDG +F+++N FDVII DS+DP+GPAE LF E +Y+ Sbjct: 124 GGILEKMLSDKHEKGKLIIGDGVKFIEENS-GFDVIIVDSTDPVGPAEMLFSEEFYKNAY 182 Query: 195 TALKEDGVLCCQGECQWLHLD----LIKEMRQFCQSL----FPVVAYAYCTIPTYPSGQI 246 AL + G+ Q +L D ++MR+ + FPV+ YA Sbjct: 183 RALNDPGIYVTQAGSVYLFTDEFLTAYRKMRKVFDKVYYYSFPVIGYA---------SPW 233 Query: 247 GFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 F++ K S +F + + ++ ++ L+YY+ D H F +P + + L Sbjct: 234 AFLVGVKG-SIDFMK----VDAEKGKKLGLEYYDPDKHETLFQMPRYIVQML 280 >2CMG-A nrPDB Length = 262 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 59/270 (21%), Positives = 109/270 (40%), Gaps = 50/270 (18%) Query: 45 RSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQ-EMIANLPLCSHPNPRKVLIIGGG 103 RS + + +F+SK +G + +L+ Q ++ + E++A++ C+ ++VLI+ G Sbjct: 25 RSEHNILEIFKSKDFGEIAMLNR--QLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGF 82 Query: 104 DGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQN 163 D + ++ K+ + VQ DE ++ F P ++ T + + + Sbjct: 83 DLELAHQLFKYDTHIDFVQA--DEKILDSFISFFPHFHEVKNNKNFT----HAKQLLDLD 136 Query: 164 QDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWL-HLDL---IKE 219 +D+I + + L K LKEDGV + L H+ + +K Sbjct: 137 IKKYDLIFCLQEPDIHRIDGL---------KRMLKEDGVFISVAKHPLLEHVSMQNALKN 187 Query: 220 MRQFCQSLFPVVA---------YAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQ 270 M P VA Y Y + T+P + +T + Sbjct: 188 MGGVFSVAMPFVAPLRILSNKGYIYASFKTHPLKDL-------------------MTPKI 228 Query: 271 VAQMQLKYYNSDVHRAAFVLPEFARKALND 300 A ++YYN D+HRAAF LP+ ++ D Sbjct: 229 EALTSVRYYNEDIHRAAFALPKNLQEVFKD 258 >3C6K-A nrPDB Length = 381 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 59/204 (28%), Positives = 95/204 (46%), Gaps = 31/204 (15%) Query: 28 WP---GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIA 84 WP G+ + ++++++ S YQ+I + SK +GN+L+L G + E D +Y I Sbjct: 139 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 197 Query: 85 NLPLCSHPNPRKVLIIGGGDGGVLREVVK-HPSVESVVQCEIDEDVIQVSKKFLPGMAIG 143 + + VLI+GGGDGG+L E+VK P + ++V EID+ VI KK++ Sbjct: 198 GSGKEDYTG-KDVLILGGGDGGILCEIVKLKPKMVTMV--EIDQMVIDGCKKYMRKTC-- 252 Query: 144 YSSSKLTLHVGDGFE------------FMKQNQDAFDVIITD------SSDPMGPAESLF 185 L GD ++ + K+ ++ FD +I D S+ P + F Sbjct: 253 --GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGRE-FDYVINDLTAVPISTSPEEDSTWEF 309 Query: 186 KESYYQLMKTALKEDGVLCCQGEC 209 L LK+DG QG C Sbjct: 310 LRLILDLSMKVLKQDGKYFTQGNC 333 >5WY0-A nrPDB Length = 230 Score = 31.2 bits (69), Expect = 0.54, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 88 LCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQ 131 L P+KV +G GD +LR + +P +E +V +I+ED ++ Sbjct: 14 LVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLR 57 >4X4W-A nrPDB Length = 416 Score = 31.2 bits (69), Expect = 0.64, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 11/96 (11%) Query: 156 GFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGE-CQWLHL 214 G +K +D + TDSSDP+ P + +S T + E +L QGE C Sbjct: 297 GLFIVKNRKDL--IKATDSSDPLKPYQDFIIDSREPDATTRVCE--LLKYQGEHC----- 347 Query: 215 DLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFML 250 L+KEM+Q+ FPV + + +IG +L Sbjct: 348 -LLKEMQQWSIPPFPVSGHDIRKVGISSGKEIGALL 382 >1X14-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 43/113 (38%), Gaps = 13/113 (11%) Query: 94 PRKVLIIGGGDGGVLREVVKHPSVESVVQC-----EIDEDVIQVSKKFL-------PGMA 141 P KV++IG G G L + S+ ++V+ E+ E V + +FL G Sbjct: 172 PAKVMVIGAGVAG-LAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSG 230 Query: 142 IGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMK 194 GY+ + E D+I+T + P PA L MK Sbjct: 231 DGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK 283 >4C7Y-A nrPDB Length = 907 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 16/28 (57%) Query: 153 VGDGFEFMKQNQDAFDVIITDSSDPMGP 180 VG GF F+KQ D D++ + P GP Sbjct: 834 VGAGFPFIKQIPDKLDIVYVNHPRPDGP 861 >6CMZ-A nrPDB Length = 466 Score = 27.3 bits (59), Expect = 8.9, Method: Compositional matrix adjust. Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 22/161 (13%) Query: 97 VLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPG--MAIGYSSSKLTLHVG 154 +L+IGGG GG V ++ ++ + V + L G + IG SK +HV Sbjct: 11 LLVIGGGPGGY---------VAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVA 61 Query: 155 DGFEFMKQNQDAFDVIITDSSDPMGPAESL-FKESYYQLMKTA----LKEDGVLCCQGEC 209 D FE + + I + + A+S+ +K+ + LK+ GV GE Sbjct: 62 DAFEQACGHAGEGALGIRVRAPEIDIAKSVAWKDGIVDRLTRGVGALLKKSGVRVLHGEA 121 Query: 210 QWLHLDLIK------EMRQFCQSLFPVVAYAYCTIPTYPSG 244 + + ++ +R C+ L +P+ P G Sbjct: 122 RVIDGKTVEVVSAGHAVRIGCEHLLLATGSEPVELPSMPFG 162 >5OBV-A nrPDB Length = 529 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 10/89 (11%) Query: 93 NPRKVLIIGGG-DGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTL 151 NP +V+ IG GGVLR VK + +D + +S + L G+A T+ Sbjct: 347 NPDEVVAIGAAIQGGVLRGDVKDVLL-------LDVTPLTLSIETLGGVATPLIKRNTTI 399 Query: 152 HVGDG--FEFMKQNQDAFDVIITDSSDPM 178 V F + NQ++ DV++ PM Sbjct: 400 PVSKSQIFSTAQDNQESVDVVVCQGERPM 428 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2O06-A nrPDB 454 e-128 2B2C-A nrPDB 380 e-106 1XJ5-A nrPDB 376 e-105 4YUX-A nrPDB 375 e-104 2PT6-A nrPDB 351 2e-97 3O4F-A nrPDB 340 5e-94 1INL-A nrPDB 331 2e-91 6QMM-B nrPDB 322 1e-88 1IY9-A nrPDB 308 1e-84 1UIR-A nrPDB 300 4e-82 6BQ5-A nrPDB 300 4e-82 1MJF-A nrPDB 290 4e-79 2ZSU-A nrPDB 250 6e-67 2CMG-A nrPDB 212 1e-55 3C6K-A nrPDB 145 3e-35 Sequences not found previously or not previously below threshold: 5E2B-A nrPDB 40 0.001 2PJD-A nrPDB 39 0.002 4OBX-A nrPDB 38 0.006 2IH5-A nrPDB 37 0.008 3LGA-A nrPDB 36 0.020 2AVN-A nrPDB 36 0.025 5JE5-A nrPDB 35 0.050 4JXJ-A nrPDB 34 0.060 4KRI-A nrPDB 34 0.076 4JDR-A nrPDB 34 0.10 2AVD-A nrPDB 34 0.10 3R9X-B nrPDB 33 0.15 4INE-A nrPDB 33 0.16 1SVC-P nrPDB 33 0.19 4YMH-A nrPDB 32 0.29 1XDU-A nrPDB 32 0.32 3DMF-A nrPDB 32 0.33 1YUB-A nrPDB 32 0.38 1KYQ-A nrPDB 32 0.39 4WXH-A nrPDB 32 0.40 5WY0-A nrPDB 32 0.43 3LDF-A nrPDB 31 0.61 3DP7-A nrPDB 31 0.74 4HTF-A nrPDB 30 0.94 2RC9-A nrPDB 30 1.1 2XHE-A nrPDB 30 1.2 1IJS-P nrPDB 30 1.5 3IWA-A nrPDB 30 1.8 6CLW-A nrPDB 30 1.8 3JWJ-A nrPDB 29 1.9 1Y8C-A nrPDB 29 2.4 2VLD-A nrPDB 29 2.9 4IGD-A nrPDB 29 3.0 4DJZ-B nrPDB 29 3.0 3ILX-A nrPDB 29 3.1 3HM2-A nrPDB 29 3.1 3JWI-A nrPDB 28 3.3 3X0D-A nrPDB 28 3.6 2JIF-A nrPDB 28 3.6 1F8S-A nrPDB 28 4.6 3E05-A nrPDB 28 6.1 2Z4F-A nrPDB 27 7.4 4MWZ-A nrPDB 27 8.3 1QZX-A nrPDB 27 9.6 >2O06-A nrPDB Length = 304 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 302/302 (100%), Positives = 302/302 (100%) Query: 1 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 60 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG Sbjct: 3 MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 62 Query: 61 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 120 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV Sbjct: 63 NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 122 Query: 121 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 180 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP Sbjct: 123 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 182 Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 240 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT Sbjct: 183 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 242 Query: 241 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND Sbjct: 243 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 302 Query: 301 VS 302 VS Sbjct: 303 VS 304 >2B2C-A nrPDB Length = 314 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 169/294 (57%), Positives = 225/294 (76%) Query: 6 DGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVL 65 +G + P + + +E WPGQA SLQV+++L H +S+YQD+LVF S TYGNVLVL Sbjct: 21 NGASDEEPTKVLKSDGQEMGGAWPGQAFSLQVKKVLFHEKSKYQDVLVFESTTYGNVLVL 80 Query: 66 DGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEI 125 DG++Q TERDEFSYQEM+A+LP+ +HP+P++VLIIGGGDGG+LREV+KH SVE V CEI Sbjct: 81 DGIVQATERDEFSYQEMLAHLPMFAHPDPKRVLIIGGGDGGILREVLKHESVEKVTMCEI 140 Query: 126 DEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLF 185 DE VI V+KKFLPGM+ G+S KL L GDGFEF+K +++ FDVIITDSSDP+GPAESLF Sbjct: 141 DEMVIDVAKKFLPGMSCGFSHPKLDLFCGDGFEFLKNHKNEFDVIITDSSDPVGPAESLF 200 Query: 186 KESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQ 245 +SYY+L++ ALKEDG+L QGE WLHL LI + F + +FP V YA + TYPSG Sbjct: 201 GQSYYELLRDALKEDGILSSQGESVWLHLPLIAHLVAFNRKIFPAVTYAQSIVSTYPSGS 260 Query: 246 IGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 +G+++C+KN + + P + LT +Q+ + L++YNS+VH+AAFVLP+F + AL Sbjct: 261 MGYLICAKNANRDVTTPARTLTAEQIKALNLRFYNSEVHKAAFVLPQFVKNALE 314 >1XJ5-A nrPDB Length = 334 Score = 376 bits (965), Expect = e-105, Method: Composition-based stats. Identities = 151/302 (50%), Positives = 211/302 (69%), Gaps = 7/302 (2%) Query: 6 DGPAASGPA---AIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNV 62 +G PA + GWF E +WPG+A SL+VE++L +S YQD++VF+S TYG V Sbjct: 30 NGDQKKEPACFSTVIPGWFSEMSPMWPGEAHSLKVEKVLFQGKSDYQDVIVFQSATYGKV 89 Query: 63 LVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQ 122 LVLDGVIQ TERDE +YQEMI +LPLCS PNP+KVL+IGGGDGGVLREV +H S+E + Sbjct: 90 LVLDGVIQLTERDECAYQEMITHLPLCSIPNPKKVLVIGGGDGGVLREVARHASIEQIDM 149 Query: 123 CEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDA-FDVIITDSSDPMGPA 181 CEID+ V+ VSK+F P +AIGY ++ L +GDG F+K + +D +I DSSDP+GPA Sbjct: 150 CEIDKMVVDVSKQFFPDVAIGYEDPRVNLVIGDGVAFLKNAAEGSYDAVIVDSSDPIGPA 209 Query: 182 ESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFP-VVAYAYCTIPT 240 + LF++ ++Q + AL+ GV+C Q E WLH+D+I+++ C+ +F V YA+ ++PT Sbjct: 210 KELFEKPFFQSVARALRPGGVVCTQAESLWLHMDIIEDIVSNCREIFKGSVNYAWTSVPT 269 Query: 241 YPSGQIGFMLCS-KNPSTNFQEPVQPLTQQQVA-QMQLKYYNSDVHRAAFVLPEFARKAL 298 YPSG IGFMLCS + P +F+ P+ P+ + LK+YN+++H AAF LP FA+K + Sbjct: 270 YPSGVIGFMLCSTEGPDVDFKHPLNPIDESSSKSNGPLKFYNAEIHSAAFCLPSFAKKVI 329 Query: 299 ND 300 Sbjct: 330 ES 331 >4YUX-A nrPDB Length = 304 Score = 375 bits (963), Expect = e-104, Method: Composition-based stats. Identities = 129/294 (43%), Positives = 190/294 (64%), Gaps = 6/294 (2%) Query: 12 GPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKT---YGNVLVLDGV 68 G I GWFRE WPGQA+SL+VE++L+ +++Q + +F S +G V+ LDG Sbjct: 11 GSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGC 70 Query: 69 IQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDED 128 IQ T+ DEF Y E++ + LCSHP P +VLIIGGGDGGVLREV++H +VE +ID + Sbjct: 71 IQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGE 130 Query: 129 VIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQ-DAFDVIITDSSDPMGPAESLFKE 187 V++ SK+ P ++ + + T+ VGDG F++Q + +DV+I D++DP GPA LF E Sbjct: 131 VMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGE 190 Query: 188 SYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQS-LFPVVAYAYCTIPTYPSGQI 246 ++Y+ + LK DG+ C QGE WL L+LI++M +F + F V YA +PTYP G I Sbjct: 191 AFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSI 250 Query: 247 GFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300 G ++CSK + +P++P+ A+ LKYY+S++H+A+F LP FAR N Sbjct: 251 GTLVCSKKAGVDVTKPLRPVEDMPFAK-DLKYYDSEMHKASFALPRFARHINNS 303 >2PT6-A nrPDB Length = 321 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 128/285 (44%), Positives = 190/285 (66%), Gaps = 3/285 (1%) Query: 17 REGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDE 76 + WF E +WPGQA SL+++++L+ +S+YQ++LVF S TYG VLVLDGVIQ TE+DE Sbjct: 40 SKKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDE 99 Query: 77 FSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKF 136 F+Y EM+ ++P+ P+ VL++GGGDGG++RE+ K+ SVE++ CEIDE VI+VSK + Sbjct: 100 FAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIY 159 Query: 137 LPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTA 196 ++ GY ++ + + D +F++ + +DVII DSSDP+GPAE+LF +++Y+ + A Sbjct: 160 FKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNA 219 Query: 197 LKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPS 256 LK +G Q E W+H+ IK M + + LF V YA +IPTYP G IG + CSK Sbjct: 220 LKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKT-D 278 Query: 257 TNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDV 301 T +P + L ++ A LKYYN + H AAF LP F K + ++ Sbjct: 279 TGLTKPNKKLESKEFA--DLKYYNYENHSAAFKLPAFLLKEIENI 321 >3O4F-A nrPDB Length = 294 Score = 340 bits (871), Expect = 5e-94, Method: Composition-based stats. Identities = 104/286 (36%), Positives = 159/286 (55%), Gaps = 6/286 (2%) Query: 15 AIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTER 74 A ++ W ET GQ + V+ +L+H ++ +QD+++F + +G V+ LDGV+Q TER Sbjct: 8 AEKKQW-HETLHDQFGQYFA--VDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTER 64 Query: 75 DEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSK 134 DEF Y EM+ ++PL +H + + VLIIGGGDG +LREV +H +VES+ EID V+ + Sbjct: 65 DEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCR 124 Query: 135 KFLPGMAIG-YSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLM 193 ++LP G Y + L + DG F+ Q FDVII+D +DP+GP ESLF ++Y+ Sbjct: 125 QYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGC 184 Query: 194 KTALKEDGVLCCQ-GECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCS 252 K L G+ Q G C + I R+ F V + IPTY G + F + Sbjct: 185 KRCLNPGGIFVAQNGVCFLQQEEAIDSHRK-LSHYFSDVGFYQAAIPTYYGGIMTFAWAT 243 Query: 253 KNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 N + + + ++ +YYN +H AAF LP++ + AL Sbjct: 244 DNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDAL 289 >1INL-A nrPDB Length = 296 Score = 331 bits (849), Expect = 2e-91, Method: Composition-based stats. Identities = 105/283 (37%), Positives = 162/283 (57%), Gaps = 9/283 (3%) Query: 19 GWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFS 78 W+ E + L +++ ++++ +S Q I +F + G V LDG+ TE+DEF Sbjct: 17 LWYFEYYTGN-NVGLFMKMNRVIYSGQSDIQRIDIFENPDLGVVFALDGITMTTEKDEFM 75 Query: 79 YQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLP 138 Y EM+A++P+ HPNP+KVLIIGGGDGG LREV+KH SVE + CE+D VI+ ++K+L Sbjct: 76 YHEMLAHVPMFLHPNPKKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARKYLK 135 Query: 139 GMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDP-MGPAESLFKESYYQLMKTAL 197 + G+ + + + +G E++++ ++ FDVII DS+DP G LF E +YQ AL Sbjct: 136 QTSCGFDDPRAEIVIANGAEYVRKFKNEFDVIIIDSTDPTAGQGGHLFTEEFYQACYDAL 195 Query: 198 KEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPST 257 KEDGV + E + + K + +FP+ + TYPSG + SK Sbjct: 196 KEDGVFSAETEDPFYDIGWFKLAYRRISKVFPITRVYLGFMTTYPSGMWSYTFASKGID- 254 Query: 258 NFQEPVQPLTQQQVAQM--QLKYYNSDVHRAAFVLPEFARKAL 298 P++ ++V + +LKYYN +VH A+F LP F +K L Sbjct: 255 ----PIKDFDPEKVRKFNKELKYYNEEVHVASFALPNFVKKEL 293 >6QMM-B nrPDB Length = 280 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 91/262 (34%), Positives = 142/262 (54%), Gaps = 4/262 (1%) Query: 39 QLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVL 98 Q+L S +Q I + ++ YG L+LD ER E Y E + + PL + + +VL Sbjct: 19 QILWEETSPFQKITIVDTEHYGRGLLLDDCWMTAERCEVCYHEYLVHPPLTTAASIARVL 78 Query: 99 IIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFE 158 +IGGGDGG +REV+++ VE V EID V+++S+++L + ++ +L + +GDG Sbjct: 79 VIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYLGAIGTAWADPRLNVKIGDGIA 138 Query: 159 FMKQNQDA-FDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLI 217 F++ DA +DVI+ D SDP GPA LF +Y+ + LK GV Q E L + Sbjct: 139 FVQTAPDASYDVILVDGSDPAGPAAGLFNREFYENCRRVLKPGGVFASQAESPDSFLAVH 198 Query: 218 KEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLK 277 EM + ++F Y +P YPSG ++ S P FQ+P + + Q++ Sbjct: 199 LEMIETLSAVFAEAKPYYGWVPMYPSGWWSWLYASDTPG-QFQKPQS--DRLAAIEPQVE 255 Query: 278 YYNSDVHRAAFVLPEFARKALN 299 YN D+H+AAF P F R+ L+ Sbjct: 256 IYNRDIHQAAFAQPNFVRRGLS 277 >1IY9-A nrPDB Length = 275 Score = 308 bits (790), Expect = 1e-84, Method: Composition-based stats. Identities = 106/283 (37%), Positives = 176/283 (62%), Gaps = 8/283 (2%) Query: 17 REGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDE 76 E W+ E + G ++++V + LH ++ +Q + + ++ +GN+L LDG++ +E+DE Sbjct: 1 SELWYTEKQTKNFG--ITMKVNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDE 58 Query: 77 FSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKF 136 F Y EM+A++PL +HPNP VL++GGGDGGV+RE++KHPSV+ +ID VI+ SKKF Sbjct: 59 FVYHEMVAHVPLFTHPNPEHVLVVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKF 118 Query: 137 LPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTA 196 LP +A ++ + V DGF + ++++ +DVI+ DS++P+GPA +LF + +Y + A Sbjct: 119 LPSIAGKLDDPRVDVQVDDGFMHIAKSENQYDVIMVDSTEPVGPAVNLFTKGFYAGIAKA 178 Query: 197 LKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPS 256 LKEDG+ Q + W +LI +++ + +FP+ IPTYPSG F + SK Sbjct: 179 LKEDGIFVAQTDNPWFTPELITNVQRDVKEIFPITKLYTANIPTYPSGLWTFTIGSKK-- 236 Query: 257 TNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 +P+ + + ++ KYY D+H+AAFVLP+F + Sbjct: 237 ---YDPL-AVEDSRFFDIETKYYTKDIHKAAFVLPKFVSDLIK 275 >1UIR-A nrPDB Length = 314 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 86/287 (29%), Positives = 152/287 (52%), Gaps = 8/287 (2%) Query: 18 EGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEF 77 +F E + P + L ++E+++ ++ +QD +F SK +G VL+LD +Q TERDE+ Sbjct: 4 GMYFFEHVT--PYETLVRRMERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEY 61 Query: 78 SYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFL 137 Y E + + + +HP P++VLI+GGG+G LREV+KHP+VE V +ID ++++V+K+ + Sbjct: 62 IYHETLVHPAMLTHPEPKRVLIVGGGEGATLREVLKHPTVEKAVMVDIDGELVEVAKRHM 121 Query: 138 PGMAIG-YSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMG---PAESLFKESYYQLM 193 P G + + L + D ++++ ++ +DV+I D +DP+G PA L+ +Y+L+ Sbjct: 122 PEWHQGAFDDPRAVLVIDDARAYLERTEERYDVVIIDLTDPVGEDNPARLLYTVEFYRLV 181 Query: 194 KTALKEDGVLCCQGECQWL-HLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCS 252 K L GV+ Q L H + + + + F V IP + GF+L S Sbjct: 182 KAHLNPGGVMGMQTGMILLTHHRVHPVVHRTVREAFRYVRSYKNHIPGF-FLNFGFLLAS 240 Query: 253 KNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 + + + L++ + A FVLP+ +AL Sbjct: 241 DAFDPAAFSEGVIEARIRERNLALRHLTAPYLEAMFVLPKDLLEALE 287 >6BQ5-A nrPDB Length = 331 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 85/301 (28%), Positives = 155/301 (51%), Gaps = 10/301 (3%) Query: 6 DGPAASGPAAIREG-WFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLV 64 + + S P R+ W+ E +L +LH S+YQDI + +K +G LV Sbjct: 15 NDKSHSPPNGYRKSCWYEEEIEENLRWCFAL--NSILHTGASQYQDIALLDTKPFGKALV 72 Query: 65 LDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCE 124 LDG +Q E DEF Y E + + L HP P+ V I+GGG+G RE+++H +++ VV C+ Sbjct: 73 LDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCD 132 Query: 125 IDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPM--GPAE 182 IDE+V++ K +L + S+L + + D ++ ++ +DVI+ D +DP+ GP Sbjct: 133 IDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCY 192 Query: 183 SLFKESYYQL-MKTALKEDGVLCCQGEC--QWLHLDLIKEMRQFCQSLFPVVAYAYCTIP 239 L+ + +Y+L +K LK+ G+ Q + H ++ + + +F V IP Sbjct: 193 KLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIP 252 Query: 240 TYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALN 299 +Y + G++L S +P E + +Q++ + + +Y + ++ L + R +LN Sbjct: 253 SY-ADIWGWVLASDSPLDLSAEELDIRMRQRIIE-ENRYLDGKTFVSSSTLSKAVRNSLN 310 Query: 300 D 300 + Sbjct: 311 N 311 >1MJF-A nrPDB Length = 281 Score = 290 bits (743), Expect = 4e-79, Method: Composition-based stats. Identities = 94/287 (32%), Positives = 159/287 (55%), Gaps = 15/287 (5%) Query: 22 RETCSLWP-GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQ 80 R +P G ++ ++++ ++ + S+YQ I V+ ++ +G +L LDG +Q E SY Sbjct: 3 RAFIEWYPRGYGVAFKIKKKIYEKLSKYQKIEVYETEGFGRLLALDGTVQLVTLGERSYH 62 Query: 81 EMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGM 140 E + + + +HP P++VL+IGGGDGG +REV++H V+ V+ EIDEDVI VSK + Sbjct: 63 EPLVHPAMLAHPKPKRVLVIGGGDGGTVREVLQHD-VDEVIMVEIDEDVIMVSKDLIKID 121 Query: 141 AIGYS------SSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMK 194 K L +GDGFEF+K N+ FDVII DS+DP+GPA+ LF E +Y+ + Sbjct: 122 NGLLEAMLNGKHEKAKLTIGDGFEFIKNNR-GFDVIIADSTDPVGPAKVLFSEEFYRYVY 180 Query: 195 TALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKN 254 AL G+ Q +L D + + + +F V Y + Y + F++ K Sbjct: 181 DALNNPGIYVTQAGSVYLFTDELISAYKEMKKVFDRVYYYSFPVIGY-ASPWAFLVGVKG 239 Query: 255 PSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDV 301 +F + + +++ ++QL+YY+ +H F +P++ R+ L + Sbjct: 240 -DIDFTK----IDRERAKKLQLEYYDPLMHETLFQMPKYIRETLQRL 281 >2ZSU-A nrPDB Length = 280 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 96/284 (33%), Positives = 156/284 (54%), Gaps = 16/284 (5%) Query: 23 ETCSLWP-GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQE 81 E +P G ++ +V++ + +S YQ I V+ ++ +G +L +DG +Q E SY E Sbjct: 5 EFIEWYPRGYGVAFKVKRKILEEQSEYQKIEVYETEGFGKLLAIDGTVQLVTEGEKSYHE 64 Query: 82 MIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMA 141 + + + +HPNPR+VLIIGGGDGG +REV+KH VE V+ EID+ VI++S K++ G+ Sbjct: 65 PLVHPAMLAHPNPRRVLIIGGGDGGAIREVLKHEEVEEVIMVEIDKKVIEISAKYI-GID 123 Query: 142 IGYSSSKL-------TLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMK 194 G L L +GDG +F+++N FDVII DS+DP+GPAE LF E +Y+ Sbjct: 124 GGILEKMLSDKHEKGKLIIGDGVKFIEENS-GFDVIIVDSTDPVGPAEMLFSEEFYKNAY 182 Query: 195 TALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKN 254 AL + G+ Q +L D + + +F V Y + Y + F++ K Sbjct: 183 RALNDPGIYVTQAGSVYLFTDEFLTAYRKMRKVFDKVYYYSFPVIGY-ASPWAFLVGVKG 241 Query: 255 PSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKAL 298 S +F + + ++ ++ L+YY+ D H F +P + + L Sbjct: 242 -SIDFMK----VDAEKGKKLGLEYYDPDKHETLFQMPRYIVQML 280 >2CMG-A nrPDB Length = 262 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 62/295 (21%), Positives = 115/295 (38%), Gaps = 52/295 (17%) Query: 20 WFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSY 79 W + + P +E L RS + + +F+SK +G + +L+ Q ++ Sbjct: 2 WITQEIT--PYLRKEYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNR--QLLFKNFLHI 57 Query: 80 Q-EMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLP 138 + E++A++ C+ ++VLI+ G D + ++ K+ + VQ DE ++ F P Sbjct: 58 ESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHIDFVQA--DEKILDSFISFFP 115 Query: 139 GMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALK 198 ++ T + + + +D+I + + L K LK Sbjct: 116 HFHEVKNNKNFT----HAKQLLDLDIKKYDLIFCLQEPDIHRIDGL---------KRMLK 162 Query: 199 EDGVLCCQGECQWL-HLDL---IKEMRQFCQSLFPVV---------AYAYCTIPTYPSGQ 245 EDGV + L H+ + +K M P V Y Y + T+P Sbjct: 163 EDGVFISVAKHPLLEHVSMQNALKNMGGVFSVAMPFVAPLRILSNKGYIYASFKTHPLKD 222 Query: 246 IGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300 + +T + A ++YYN D+HRAAF LP+ ++ D Sbjct: 223 L-------------------MTPKIEALTSVRYYNEDIHRAAFALPKNLQEVFKD 258 >3C6K-A nrPDB Length = 381 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 31/262 (11%) Query: 13 PAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCT 72 P +R G G+ + ++++++ S YQ+I + SK +GN+L+L G + Sbjct: 127 PPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLA 186 Query: 73 ERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVK-HPSVESVVQCEIDEDVIQ 131 E D +Y I + + VLI+GGGDGG+L E+VK P + V EID+ VI Sbjct: 187 ESD-LAYTRAIMGSGKEDYTG-KDVLILGGGDGGILCEIVKLKPKM--VTMVEIDQMVID 242 Query: 132 VSKKFLPGMAIGYSSSKLTLHVGDGFE------------FMKQNQDAFDVIITD------ 173 KK++ L GD ++ + K+ ++ FD +I D Sbjct: 243 GCKKYMRKTC----GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGRE-FDYVINDLTAVPI 297 Query: 174 SSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAY 233 S+ P + F L LK+DG QG C L + + + L+ V + Sbjct: 298 STSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNL-TEALSLYEEQLGRLYCPVEF 356 Query: 234 AYCT--IPTYPSGQIGFMLCSK 253 + +P+Y + + + K Sbjct: 357 SKEIVCVPSYLELWVFYTVWKK 378 >5E2B-A nrPDB Length = 241 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 101 GGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFM 160 G G G + + ++ P V +I ED + +K +L G ++ + G + Sbjct: 87 GAGIGRITKRLLL-PLFREVDMVDITEDFLVQAKTYL-----GEEGKRVRNYFCCGLQDF 140 Query: 161 KQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLC 204 D++DVI +G + + K +L+ +G++ Sbjct: 141 TPEPDSYDVIWIQWV--IGHLTDQHLAEFLRRCKGSLRPNGIIV 182 >2PJD-A nrPDB Length = 343 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 35/195 (17%), Positives = 64/195 (32%), Gaps = 21/195 (10%) Query: 41 LHHRRSRYQDILVFRSKTYGNVLVLDGVIQCT-----ERDEFSYQEMIANLPLCSHPNPR 95 L+ R Q VF ++ + +DG+ T RD + L H + Sbjct: 142 LYFGRLEKQ--PVFDAEKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGK 199 Query: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155 VL +G G G + +H + C++ ++ S+ L A G Sbjct: 200 -VLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLA--ANGVEGEVF------ 250 Query: 156 GFEFMKQNQDAFDVIITDSSDPMGPA---ESLFKESYYQLMKTALKEDGVLCCQGECQWL 212 + + FD+II S+ P ++ + L G L Sbjct: 251 ASNVFSEVKGRFDMII--SNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLP 308 Query: 213 HLDLIKEMRQFCQSL 227 + D++ E F + + Sbjct: 309 YPDVLDETFGFHEVI 323 >4OBX-A nrPDB Length = 257 Score = 37.7 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 21/165 (12%), Positives = 54/165 (32%), Gaps = 20/165 (12%) Query: 94 PRKVLIIGGGDGGVLREVVKH------PSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSS 147 P + + GG G + ++ H + ++ +I+ D+++ +K + Sbjct: 62 PLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDP 121 Query: 148 KLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVL---- 203 ++ V +G + + + D+ D+ G + LK G+ Sbjct: 122 RVRFLVSNGEKLEEIDSDSKDIYTVS----FGIRNFTDIQKGLNTAYRVLKPGGIFYCLE 177 Query: 204 CCQGECQWLHLD------LIKEMRQFCQSLFPVVAYAYCTIPTYP 242 + E + ++ M + + Y +I +P Sbjct: 178 FSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFP 222 >2IH5-A nrPDB Length = 421 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 48/141 (34%), Gaps = 22/141 (15%) Query: 114 HPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITD 173 H + V EID + LP A G + L G+ F+ + N + ++ Sbjct: 61 HGTAYRFVGVEIDPKALD-----LPPWAEGILADFLLWEPGEAFDLILGNP-PYGIVGEA 114 Query: 174 SSDPMG---PAESLFKESY-------------YQLMKTALKEDGVLCCQGECQWLHLDLI 217 S P+ + L+K+++ + LK GVL WL L+ Sbjct: 115 SKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLVLEDF 174 Query: 218 KEMRQFCQSLFPVVAYAYCTI 238 +R+F Y + Sbjct: 175 ALLREFLAREGKTSVYYLGEV 195 >3LGA-A nrPDB Length = 253 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 40/111 (36%), Gaps = 14/111 (12%) Query: 119 SVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPM 178 VV EI E +K + ++T+ + D +E +++ + D +I D P Sbjct: 120 RVVSYEIRE---DFAKLAWENIKWAGFDDRVTIKLKDIYEGIEE--ENVDHVILDLPQP- 173 Query: 179 GPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFP 229 E + ALK G C + L +++R+F Sbjct: 174 --------ERVVEHAAKALKPGGFFVAYTPCSNQVMRLHEKLREFKDYFMK 216 >2AVN-A nrPDB Length = 260 Score = 35.8 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 29/182 (15%), Positives = 61/182 (33%), Gaps = 40/182 (21%) Query: 79 YQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSK-KFL 137 Y +I + NP +VL +GGG G + VV + +++++V++ K + Sbjct: 40 YHRLIGSFLEEYLKNPCRVLDLGGGTGKW--SLFLQERGFEVVLVDPSKEMLEVAREKGV 97 Query: 138 PGMAIGYSSS--------KLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESY 189 + + + L +GD +++ AF I Sbjct: 98 KNVVEAKAEDLPFPSGAFEAVLALGDVLSYVENKDKAFSEI------------------- 138 Query: 190 YQLMKTALKEDGVLCCQGECQWLHL------DLIKEMRQFCQSLFPVVAYAYCTIPTYPS 243 + L DG+L + + L D ++ +F ++ V + +Y Sbjct: 139 ----RRVLVPDGLLIATVDNFYTFLQQMIEKDAWDQITRFLKTQTTSVGTTLFSFNSYAF 194 Query: 244 GQ 245 Sbjct: 195 KP 196 >5JE5-A nrPDB Length = 247 Score = 34.7 bits (78), Expect = 0.050, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 49/129 (37%), Gaps = 25/129 (19%) Query: 95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 + VL + G G RE+ + + VV +I E +I+++++ + Y L HV Sbjct: 43 KSVLDLACGFGFFGREIYRRGAA-KVVGVDISEKMIELARE----ESRKYGDP-LEFHVR 96 Query: 155 DGFEFMKQNQDAFDVIITDSSDPMGPAESLFK--------ESYYQLMKTALKEDGVLCCQ 206 D + FD++ A LF +++++ +LK DG L Sbjct: 97 DVANM--EPLGQFDLV---------NAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAY 145 Query: 207 GECQWLHLD 215 L Sbjct: 146 TVDPDFSLA 154 >4JXJ-A nrPDB Length = 276 Score = 34.3 bits (77), Expect = 0.060, Method: Composition-based stats. Identities = 33/186 (17%), Positives = 63/186 (33%), Gaps = 16/186 (8%) Query: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155 VL IG G GG+ R ++ H + + + E DE L + L + D Sbjct: 53 NVLEIGPGTGGLTRSIL-HKNPKLLTVIETDER----CIPLLNEIKQ--YHPNLNIIKQD 105 Query: 156 GFEFMKQNQDAFDVIITDSSDPMGPAE-----SLFKESYYQLMKTALKE---DGVLCCQG 207 + + + + I S+ P L + S M L++ + + Sbjct: 106 ALKLKLSDLNTNKITII-SNLPYHIGTELVIRWLKESSLVASMTLMLQKEVVERICAKPS 164 Query: 208 ECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLT 267 + L +I + + F V A+ P S + P+++ V+ +T Sbjct: 165 TKAYGRLSVICSLIATVEKCFDVAPTAFYPPPKVYSAIVKLTPLENIPNSDLISKVELIT 224 Query: 268 QQQVAQ 273 + A Sbjct: 225 KMAFAG 230 >4KRI-A nrPDB Length = 433 Score = 34.3 bits (77), Expect = 0.076, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 47/109 (43%), Gaps = 12/109 (11%) Query: 95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 +++L IG G GG R+ + V ++ +++ V+ L + +++T V Sbjct: 224 QRMLDIGVGIGGGARQAASEFGL-QVHGVDLSTNMLAVA---LERVHKEK-DARVTYAVC 278 Query: 155 DGFEFMKQNQDAFDVIIT-DSSDPMGPAESLFKESYYQLMKTALKEDGV 202 D E+ + ++FD + + D + + LF + ALK G Sbjct: 279 DACEY-EFEPNSFDYVFSRDCIQHIKDTDKLFSR-----IYRALKPGGK 321 >4JDR-A nrPDB Length = 474 Score = 33.5 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 36/94 (38%) Query: 87 PLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSS 146 L P ++L++GGG G+ V H + E+ + VI + K + + S Sbjct: 168 ALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRIS 227 Query: 147 SKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 180 K L + ++ +D V + P P Sbjct: 228 KKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEP 261 >2AVD-A nrPDB Length = 229 Score = 33.5 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 34/91 (37%), Gaps = 15/91 (16%) Query: 119 SVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQ-----NQDAFDVIITD 173 VV CE+D ++ + P + K+ L + E + + FDV + D Sbjct: 96 RVVTCEVDAQPPELGR---PLWRQAEAEHKIDLRLKPALETLDELLAAGEAGTFDVAVVD 152 Query: 174 SSDPMGPAESLFKESYYQLMKTALKEDGVLC 204 A+ +YY+ L+ G+L Sbjct: 153 -------ADKENCSAYYERCLQLLRPGGILA 176 >3R9X-B nrPDB Length = 248 Score = 33.1 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 31/63 (49%), Gaps = 9/63 (14%) Query: 97 VLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDG 156 V+ +GGG G + + +++HP ++ + E+D ++++ K +L + D Sbjct: 34 VVEVGGGTGNLTKVLLQHP-LKKLYVIELDREMVENLKS--------IGDERLEVINEDA 84 Query: 157 FEF 159 +F Sbjct: 85 SKF 87 >4INE-A nrPDB Length = 454 Score = 33.1 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 12/106 (11%) Query: 98 LIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGF 157 L IG G GG R+V V V ++ +++ ++ L + S++ + D Sbjct: 246 LDIGVGIGGGARQVADEFGV-HVHGIDLSSNMLAIA---LERLHEEK-DSRVKYSITDAL 300 Query: 158 EFMKQNQDAFDVIIT-DSSDPMGPAESLFKESYYQLMKTALKEDGV 202 + + ++FD + + D + E LF + ALK G Sbjct: 301 VY-QFEDNSFDYVFSRDCIQHIPDTEKLFSR-----IYKALKPGGK 340 >1SVC-P nrPDB Length = 365 Score = 32.7 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 49/120 (40%), Gaps = 10/120 (8%) Query: 85 NLPLCSHPNPRKVLIIGGGD---GGVLREVVKHPSVESVVQCEIDEDVIQV-SKKFLPGM 140 N L HP+ + GGGD G +E+++ +++ E+D V+++ FLP Sbjct: 166 NPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTK--EMDLSVVRLMFTAFLPDS 223 Query: 141 AIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKED 200 ++ +L V D + + +A ++ I G E Y L K+D Sbjct: 224 TGSFT-RRLEPVVSDAI-YDSKAPNASNLKIVRMDRTAGCVTG--GEEIYLLCDKVQKDD 279 >4YMH-A nrPDB Length = 240 Score = 32.3 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 93 NPRKVLIIGGGDGGVL---REVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKL 149 P+++L IG G E + + +V E +I S++ +G ++ Sbjct: 65 KPKRILEIGCYSGYSALAWYEGTR-DTKAEIVTLEYSPKMIAASREAFKKYGVG---DRV 120 Query: 150 TLHVGDGFEFMKQNQDAFDVIITDSSDP 177 L G +K + FD+I D++ Sbjct: 121 KLIEGPAENTLKTLEGEFDLIFVDANKD 148 >1XDU-A nrPDB Length = 374 Score = 32.0 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 40/107 (37%), Gaps = 9/107 (8%) Query: 95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 R VL +GGG+GG+L + E+ + ++F G + ++T+ G Sbjct: 184 RHVLDVGGGNGGMLAAIALRAPHLRGTLVELAGPAERARRRF---ADAGLAD-RVTVAEG 239 Query: 155 DGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDG 201 D F+ + D + + A + + AL+ G Sbjct: 240 DFFKPLPVTADVVLLSFVLLNWSDEDALT-----ILRGCVRALEPGG 281 >3DMF-A nrPDB Length = 381 Score = 32.0 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 55/134 (41%), Gaps = 9/134 (6%) Query: 95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 R+VL +G G G + + + + VV E D + +K L A+ K Sbjct: 235 RQVLDLGAGYGALTLPLARMGA--EVVGVEDDLASVLSLQKGLEANAL-----KAQALHS 287 Query: 155 DGFEFMKQNQDAFDVIITDSSDPMGPAESL-FKESYYQLMKTALKEDGVLCCQGECQWLH 213 D E + + + FD+I+T+ +G A L +++ + L+ GV + Sbjct: 288 DVDEALTE-EARFDIIVTNPPFHVGGAVILDVAQAFVNVAAARLRPGGVFFLVSNPFLKY 346 Query: 214 LDLIKEMRQFCQSL 227 L++E Q+L Sbjct: 347 EPLLEEKFGAFQTL 360 >1YUB-A nrPDB Length = 245 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 29/73 (39%), Gaps = 3/73 (4%) Query: 29 PGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPL 88 P + +++++ R+ L+ Y L + + + S Q+++ Sbjct: 102 PYHLSTQIIKKVVFESRAS-DIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE 160 Query: 89 CSHPNPR--KVLI 99 C HP P+ VLI Sbjct: 161 CFHPKPKVNSVLI 173 >1KYQ-A nrPDB Length = 274 Score = 31.6 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 38/100 (38%), Gaps = 10/100 (10%) Query: 82 MIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMA 141 M+ +L L +++L+IGGG+ G+ R P+ + D + K +P Sbjct: 1 MVKSLQLAHQLKDKRILLIGGGEVGLTRLYKLMPTGCKLTLVSPD-----LHKSIIPKFG 55 Query: 142 IGYSSSKLTLHVGDGFEFMK-----QNQDAFDVIITDSSD 176 + + D F+ + ++ I +D D Sbjct: 56 KFIQNKDQPDYREDAKRFINPNWDPTKNEIYEYIRSDFKD 95 >4WXH-A nrPDB Length = 367 Score = 31.6 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 42/110 (38%), Gaps = 9/110 (8%) Query: 92 PNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTL 151 N R VL +GGG GG + + S E+ V ++ +L G S ++ + Sbjct: 188 TNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTV-DTARSYLKD--EGLSD-RVDV 243 Query: 152 HVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDG 201 GD FE + + DA + + P A + AL+ G Sbjct: 244 VEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTR-----CAEALEPGG 288 >5WY0-A nrPDB Length = 230 Score = 31.6 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 4/89 (4%) Query: 88 LCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSS 147 L P+KV +G GD +LR + +P +E +V +I+ED ++ L + Sbjct: 14 LVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLRWRGDSLAPFLGDFLKP 73 Query: 148 K---LTLHVGDGFEFMKQNQ-DAFDVIIT 172 + LT+ + G + ++ FD+I Sbjct: 74 RDLNLTITLYHGSVVERDSRLLGFDLITC 102 >3LDF-A nrPDB Length = 385 Score = 31.2 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 65/172 (37%), Gaps = 19/172 (11%) Query: 89 CSHPNPRKVLIIGGGDGGVLREVVKHP---SVESVVQCEIDEDVIQVSKK-------FLP 138 R LI G G + + + SV + + + + ++K+ Sbjct: 197 LDQRQVRNELINGSAAGKTVLNLFSYTAAFSVAAAMGGAMATTSVDLAKRSRALSLAHFE 256 Query: 139 GMAIGYSSSKLTLH-VGDGFEFMKQNQDAFDVIITDSSDPMGPAESLF--KESYYQLMKT 195 + ++ +L + V D F++ +++ +D+II D + +F + Y++L++ Sbjct: 257 ANHLDMANHQLVVMDVFDYFKYARRHHLTYDIIIIDPPSFARNKKEVFSVSKDYHKLIRQ 316 Query: 196 ---ALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSG 244 L E+G++ + + K + + F + Y + PS Sbjct: 317 GLEILSENGLIIASTNAANMTVSQFK---KQIEKGFGKQKHTYLDLQQLPSD 365 >3DP7-A nrPDB Length = 363 Score = 30.8 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 34/85 (40%), Gaps = 11/85 (12%) Query: 89 CSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSK 148 SH +P+++L IGG G + V++ V ++ + + + + G S S Sbjct: 176 FSH-HPKRLLDIGGNTGKWATQCVQYNKEVEVTIVDLPQQL-----EMMRKQTAGLSGS- 228 Query: 149 LTLHVGDGFEFMKQN---QDAFDVI 170 G G + ++ FD + Sbjct: 229 -ERIHGHGANLLDRDVPFPTGFDAV 252 >4HTF-A nrPDB Length = 285 Score = 30.4 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 73/205 (35%), Gaps = 30/205 (14%) Query: 92 PNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTL 151 P +VL GGG+G ++ + V+ C++ +I +K+ + + + Sbjct: 67 PQKLRVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC 124 Query: 152 HVGDGFEFMKQNQD--AFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQ--G 207 D ++ D F ++ +DP S Q + + L+ GVL Sbjct: 125 AAQDVASHLETPVDLILFHAVLEWVADP---------RSVLQTLWSVLRPGGVLSLMFYN 175 Query: 208 ECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQ-----I----GFMLCSKNPSTN 258 L +++ + Q+ P + P YP G+ + K Sbjct: 176 AHGLLMHNMVAGNFDYVQAGMPKKKKRTLS-PDYPRDPTQVYLWLEEAGWQIMGKTGVRV 234 Query: 259 FQEPVQPLTQQQ-----VAQMQLKY 278 F + ++ QQ+ + +++ +Y Sbjct: 235 FHDYLREKHQQRDCYEALLELETRY 259 >2RC9-A nrPDB Length = 294 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 29/90 (32%), Gaps = 24/90 (26%) Query: 84 ANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIG 143 + P HP+ G G +RE S E V ++ P M Sbjct: 159 IHDPKLHHPSQ-------GFRFGTVRE----SSAEDYV------------RQSFPEMHEY 195 Query: 144 YSSSKLTLHVGDGFEFMKQNQDAFDVIITD 173 + DG +++K + + D I D Sbjct: 196 MRRYNVPAT-PDGVQYLKNDPEKLDAFIMD 224 >2XHE-A nrPDB Length = 650 Score = 30.0 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 43/101 (42%), Gaps = 11/101 (10%) Query: 99 IIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFE 158 + GGD VL VV P++ + +C +++ + + ++ + L G Sbjct: 19 VADGGDWKVL--VVDKPALRMISECARMSEILDLGVTVVEDVSK----QRKVLPQFHGVY 72 Query: 159 FMKQNQDAFDVIITDSSD--PMGPAESLFKESYYQLMKTAL 197 F++ ++ D +I D +D P A LF + + AL Sbjct: 73 FIEPTEENLDYVIRDFADRTPTYEAAHLF---FLSPVPDAL 110 >1IJS-P nrPDB Length = 584 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 23/72 (31%), Gaps = 4/72 (5%) Query: 176 DPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQW-LHLDLIKEMRQFCQSLFPVVAYA 234 P+ P ++ + + +K L + CQ C L + + + P + Sbjct: 461 PPVYPNGQIWDKEFDTDLKPRLHVNAPFVCQNNCPGQLFVKVAPNLTNQYD---PDASAN 517 Query: 235 YCTIPTYPSGQI 246 I TY Sbjct: 518 MSRIVTYSDFWW 529 >3IWA-A nrPDB Length = 472 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 29/142 (20%) Query: 30 GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLC 89 G+ +L+ ++L+ S+ V + L GV T DE E + + Sbjct: 107 GERRTLKYDKLVLALGSKANRPPV-------EGMDLAGVTPVTNLDE---AEFVQHA--I 154 Query: 90 SHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKL 149 S K +I+GGG G+ +V ID V++++ + +P G++S L Sbjct: 155 SAGEVSKAVIVGGGFIGL------EMAVSLADMWGIDTTVVELADQIMP----GFTSKSL 204 Query: 150 TLHVGDGFEFMKQNQDAFDVII 171 + + ++ + + DV++ Sbjct: 205 S-------QMLRHDLEKNDVVV 219 >6CLW-A nrPDB Length = 364 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 15/27 (55%) Query: 87 PLCSHPNPRKVLIIGGGDGGVLREVVK 113 R V+ +GGG GGVL EV++ Sbjct: 183 AGFDWSAVRHVMDVGGGTGGVLAEVLR 209 >3JWJ-A nrPDB Length = 202 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 40/90 (44%), Gaps = 2/90 (2%) Query: 80 QEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPG 139 Q M + N R+V+ +G G G +L+ ++K E + ++ ++++++ L Sbjct: 6 QRMNGVVAALKQSNARRVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIAQERLDR 65 Query: 140 MAIGYSS-SKLTLHVGDGFEFMKQNQDAFD 168 + + + +L L G + + +D Sbjct: 66 LRLPRNQWERLQLIQG-ALTYQDKRFHGYD 94 >1Y8C-A nrPDB Length = 246 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Query: 166 AFDVIIT--DSSDPMGPAESLFKESYYQLMKTALKEDGVLC 204 FD+I DS++ + ++ L + Y++ + LKE GV Sbjct: 101 KFDLITCCLDSTNYIIDSDDL--KKYFKAVSNHLKEGGVFI 139 >2VLD-A nrPDB Length = 251 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 47/121 (38%), Gaps = 9/121 (7%) Query: 11 SGPAAIREGWFRETCSLWP-GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVI 69 G I + RE + P G ++ + ++ RR Y+ + V + Y V+ L Sbjct: 59 DGSFLIHQNKKREPVNWQPPGSKVTFKENSMISIRRRPYERLEVEIIEPYSLVVFL---- 114 Query: 70 QCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDV 129 + +E + A + NPR +I G + RE + V+ + D ++ Sbjct: 115 -AEDYEELALTGSEAEMANLIFENPR---VIEEGFKPIYREKPIRHGIVDVMGVDKDGNI 170 Query: 130 I 130 + Sbjct: 171 V 171 >4IGD-A nrPDB Length = 406 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 18/39 (46%) Query: 5 PDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHH 43 P+GP G I GW ++ +P + +++ + H Sbjct: 281 PEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHS 319 >4DJZ-B nrPDB Length = 251 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 18/39 (46%) Query: 5 PDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHH 43 P+GP G I GW ++ +P + +++ + H Sbjct: 126 PEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHS 164 >3ILX-A nrPDB Length = 143 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 7/47 (14%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 153 VGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKE 199 + + +++++ +D++ITD +G ++ ++ + +L++ L Sbjct: 20 LANQVKYLEEQVKEYDLVITD----IGSGLNMKRKGFLKLLRMILNN 62 >3HM2-A nrPDB Length = 178 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 39/117 (33%), Gaps = 13/117 (11%) Query: 92 PNPRKVLI-IGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLT 150 P P + L IGGG G + E ++ + V EI E+ + + + +G S ++ Sbjct: 23 PKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRE--RILSNAINLGVSD-RIA 79 Query: 151 LHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQG 207 + G F D DVI L + L G L Sbjct: 80 VQQGAPRAF-DDVPDNPDVIFI--------GGGLTAPGVFAAAWKRLPVGGRLVANA 127 >3JWI-A nrPDB Length = 207 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 28/53 (52%) Query: 86 LPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLP 138 + + N +KV+ +G G+G +L ++K S E + ++ V++ +K L Sbjct: 20 VAVLKSVNAKKVIDLGCGEGNLLSLLLKDKSFEQITGVDVSYSVLERAKDRLK 72 >3X0D-A nrPDB Length = 655 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 41 LHHRRSRYQDILVFRSKTY-GNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLI 99 + R++ Y +F ++ + V L + E S+ L L + ++V I Sbjct: 360 MLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSF------LGLLAAKTAKRVTI 413 Query: 100 IGGGDGGVLREV-VKHPSVESVVQCEIDEDV 129 I G + R++ K+ + EI E V Sbjct: 414 IDGNE--RFRDIFFKYIHYYKLTNVEIIEKV 442 >2JIF-A nrPDB Length = 404 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 30/97 (30%), Gaps = 9/97 (9%) Query: 190 YQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFM 249 + L A KE G W+ + ++ P + Y G F+ Sbjct: 158 FALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGY---------KGITSFL 208 Query: 250 LCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRA 286 + P + +P L + + L + N V A Sbjct: 209 VDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEA 245 >1F8S-A nrPDB Length = 498 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 52/130 (40%), Gaps = 4/130 (3%) Query: 76 EFSYQEMI--ANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVS 133 E Y+E + A L + NP+ V+I+G G G+ V + V E E Sbjct: 13 ENDYEEFLEIARNGLKATSNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRV 72 Query: 134 KKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLM 193 + + G+ ++ + + + +++ FD+ + + S F ++ + + Sbjct: 73 RTY-RNEEAGWYANLGPMRLPEKHRIVREYIRKFDLRLNEFSQ-ENDNAWYFIKNIRKKV 130 Query: 194 KTALKEDGVL 203 K+ G+L Sbjct: 131 GEVKKDPGLL 140 >3E05-A nrPDB Length = 204 Score = 27.7 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 2/32 (6%) Query: 81 EMIANLPLCSHPNPRKVLIIGGGDGGVLREVV 112 E A L P+P +V I GG GG+L E++ Sbjct: 96 EAFAPEGLDDLPDPDRVFI--GGSGGMLEEII 125 >2Z4F-A nrPDB Length = 173 Score = 27.3 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 12/24 (50%) Query: 155 DGFEFMKQNQDAFDVIITDSSDPM 178 G + + N + +D+ + D P+ Sbjct: 115 HGKQVLDGNSNPYDIFLKDLEPPI 138 >4MWZ-A nrPDB Length = 267 Score = 27.3 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 20/149 (13%) Query: 96 KVLIIGGGDGGVLREV-VKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVG 154 KVL IG G GG + + K+ + V +I E ++ ++K + K + Sbjct: 58 KVLDIGSGLGGGCKYINEKYGAHVHGV--DICEKMVTIAK--------LRNQDKAKIEF- 106 Query: 155 DGFEFMKQN--QDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWL 212 + + +K++ + FD+I S D + K+ ++ LK +G+L C Sbjct: 107 EAKDILKKDFPESTFDMIY--SRDSILHLSYADKKMLFEKCYKWLKPNGILLITDYCA-- 162 Query: 213 HLDLIKEMRQFCQSLFPVVAYAYCTIPTY 241 D I+ + ++ Y I Y Sbjct: 163 --DKIENWDEEFKAYIKKRKYTLMPIQEY 189 >1QZX-A nrPDB Length = 440 Score = 27.0 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 21/62 (33%), Gaps = 1/62 (1%) Query: 142 IGYSSSKLTLHVGDGFEFMKQN-QDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKED 200 Y + + + ++ D+II D++ G E + M LK D Sbjct: 161 QVYGEPNNQNPIEIAKKGVDIFVKNKMDIIIVDTAGRHGYGEETKLLEEMKEMYDVLKPD 220 Query: 201 GV 202 V Sbjct: 221 DV 222 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.134 0.354 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,665,566 Number of Sequences: 36641 Number of extensions: 444799 Number of successful extensions: 1573 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1455 Number of HSP's gapped (non-prelim): 87 length of query: 302 length of database: 10,336,785 effective HSP length: 97 effective length of query: 205 effective length of database: 6,782,608 effective search space: 1390434640 effective search space used: 1390434640 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)