BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P18886 (658 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2FYO-A nrPDB 1320 0.0 1T7N-A nrPDB 285 5e-77 1S5O-A nrPDB 252 4e-67 2FY4-A nrPDB 248 5e-66 1T1U-A nrPDB 243 3e-64 1XMD-A nrPDB 241 5e-64 6BVE-A nrPDB 30 2.6 1GE6-A nrPDB 29 5.0 >2FYO-A nrPDB Length = 653 Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust. Identities = 632/632 (100%), Positives = 632/632 (100%) Query: 27 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN 86 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN Sbjct: 22 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN 81 Query: 87 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN 146 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN Sbjct: 82 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN 141 Query: 147 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL 206 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL Sbjct: 142 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL 201 Query: 207 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP 266 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP Sbjct: 202 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP 261 Query: 267 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC 326 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC Sbjct: 262 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC 321 Query: 327 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE 386 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE Sbjct: 322 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE 381 Query: 387 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI 446 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI Sbjct: 382 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI 441 Query: 447 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 506 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS Sbjct: 442 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 501 Query: 507 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR 566 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR Sbjct: 502 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR 561 Query: 567 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS 626 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS Sbjct: 562 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS 621 Query: 627 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT 658 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT Sbjct: 622 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT 653 >1T7N-A nrPDB Length = 618 Score = 285 bits (729), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 201/638 (31%), Positives = 320/638 (50%), Gaps = 75/638 (11%) Query: 43 MHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLL 100 M +QD+LPRLP+P L+ ++ YL A +P++ + ++ T+ L F+T GVG+ L L Sbjct: 21 MAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGL- 79 Query: 101 AQDKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSA 159 + + K +++S W YL R +V+ +P + PK ++ D Sbjct: 80 -ERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVIL---PKQDFVD--------LQGQ 127 Query: 160 VRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 219 +RF L G+L+ FK +I + + G PL M+QY++ Sbjct: 128 LRFAAKLIEGVLD---------------FKSMIDNETLPVEFLGGQ-----PLCMNQYYQ 167 Query: 220 LFNSTRIPRPNRDELFTDTKAR----HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKY 275 + +S R+P P +D + K++ H+ V+ F+ DV DG + +I L+ Sbjct: 168 ILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEK 227 Query: 276 ILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLD-DFP-M 332 I + S + PV LTS +R+ WA+ LI D N E++ + ++F +CLD P + Sbjct: 228 IWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRV 287 Query: 333 KDLIHLSHT---MLHGDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFF 384 D ++ +H MLHG G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ Sbjct: 288 SDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALV 347 Query: 385 NEVFRDSTQTPAIT-----PQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVK 439 + V + T+ P + P P + L FN++ +K I AK+ ++ Sbjct: 348 DHVM-EYTKKPELVRSPMVPLPMP---------KKLRFNITPEIKNDIEKAKQNLSIMIQ 397 Query: 440 TLSIDSIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRT 499 L I + F GK+F K ++LSPDA Q+A Q+A+ R YGQ ATYES S F GRT Sbjct: 398 DLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRT 457 Query: 500 ETIRPASIFTKRCSEAFVRDPSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLY 557 +TIR ASI S AFV+ +V E Q ++ + + H T A G+ FDRHL Sbjct: 458 DTIRSASI----DSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLL 513 Query: 558 ALRYLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVH 617 L+ A +++P++++D +Y H LSTS + + +G F PVVPDG+GI Y Sbjct: 514 GLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVGFFGPVVPDGYGICYNPM 573 Query: 618 DDWIGCNVSSYSG---RNAREFLHCVQKCLEDIFDALE 652 + I +VS+Y+ NA H ++K L D+ L+ Sbjct: 574 EAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQ 611 >1S5O-A nrPDB Length = 616 Score = 252 bits (643), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 186/618 (30%), Positives = 304/618 (49%), Gaps = 75/618 (12%) Query: 58 EDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQDKQNKHTSYISGP 115 + ++ YL A +P++ + ++ T+ L F+ GVG+ L L + + K +++S Sbjct: 23 QQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGL--ERRARKTENWLSEW 80 Query: 116 WFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLQAGLLEPE 174 W YL R +V+ +P + PK ++ D +RF L G+L+ Sbjct: 81 WLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQLRFAAKLIEGVLD-- 127 Query: 175 VFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPRPNRDEL 234 FK +I + + G PL M+QY+++ +S R+P P +D + Sbjct: 128 -------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQILSSCRVPGPKQDTV 169 Query: 235 --FTDTKA--RHLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKYILSDSSPVPEFPVAY 290 F+ TK H+ V+ F+ DV DG + +I L+ I + S + PV Sbjct: 170 SNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGI 229 Query: 291 LTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLD-DFP-MKDLIHLSHT---MLH 344 LTS +R+ WA+ LI D N ++++ + ++F +CLD P + + ++ SH MLH Sbjct: 230 LTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLH 289 Query: 345 GDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNEVFRDSTQTPAIT- 398 G G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ + V + T+ P + Sbjct: 290 GGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVI-EYTKKPELVR 348 Query: 399 ----PQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSIQFQRGGKE 454 P P + L FN++ +K+ I AK+ ++ L I + F GK+ Sbjct: 349 SPMVPLPMP---------KKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKD 399 Query: 455 FLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSE 514 F K ++LSPDA Q+A Q+A+ R YGQ ATYES S F GRT+TIR AS+ S Sbjct: 400 FPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASM----DSL 455 Query: 515 AFVRDPSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATARGLNLPE 572 FV+ SV E Q ++ + + H T A G+ FDRHL L+ A ++ P+ Sbjct: 456 TFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPD 515 Query: 573 LYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSG-- 630 +++D +Y H LSTS + + + F PVVPDG+G+ Y + I ++S+Y+ Sbjct: 516 IFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCA 575 Query: 631 -RNAREFLHCVQKCLEDI 647 NA H ++K L D+ Sbjct: 576 ETNAARLAHYLEKALLDM 593 >2FY4-A nrPDB Length = 612 Score = 248 bits (633), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 184/632 (29%), Positives = 302/632 (47%), Gaps = 70/632 (11%) Query: 46 QDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQD 103 + LP+LP+P L+ T+ YL + L+ + QFR+++A+ + F G+G+ L LL + Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLL--E 67 Query: 104 KQNKHTSYISGPWF-DMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRF 162 +Q K +++S W DMYL R ++ +N +P + F +DQL RF Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQL-----------RF 116 Query: 163 LKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFN 222 +L +G+L + L+ TD K + + PL M QY+ LF+ Sbjct: 117 AASLISGVLSYKAL-LDSHSIPTDCAKGQL---------------SGQPLCMKQYYGLFS 160 Query: 223 STRIPRPNRDELFTDTKA-----RHLLVLRKGHFYVFDVLDQ-----DGNIVNPLEIQAH 272 S R+P +D L + H++V F+V DV+ +G++ +++ Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFT--QLRKI 218 Query: 273 LKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDDFP 331 +K + ++ +P P+ LTS+ R WAE R L+ D N ++L ++ + +CLD Sbjct: 219 VKMASNAAARLP--PIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPG 276 Query: 332 MKDL--IHLSHTMLHG-----DGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFF 384 +L H + +LHG +G NRW+DKS +V DGT V EHS DG+ +++ Sbjct: 277 GVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCT 336 Query: 385 NEVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSID 444 + + TQ + P + L + S ++ + ++ EK VK L Sbjct: 337 EHLLKHMTQPELVRSPMVPLP-----APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 391 Query: 445 SIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRP 504 +F GK F+KK++ SPDA Q+A Q+AF R + + V TYES S F+ GR + IR Sbjct: 392 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 451 Query: 505 ASIFTKRCSEAFVRDPSKHSVG----ELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALR 560 A+ + AFVR + H E ++ + + T A G D HL ALR Sbjct: 452 ATPE----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR 507 Query: 561 YLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDW 620 LA A LPE+++D Y N +LSTS + + + PVVP+G+G Y + Sbjct: 508 ELARAMCAALPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET 567 Query: 621 IGCNVSSY---SGRNAREFLHCVQKCLEDIFD 649 I +SS+ + ++ +F V++ L D+ D Sbjct: 568 ILFCISSFHSCAATSSSKFAKAVEESLIDMRD 599 >1T1U-A nrPDB Length = 639 Score = 243 bits (619), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 183/632 (28%), Positives = 297/632 (46%), Gaps = 73/632 (11%) Query: 49 LPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQDKQN 106 LP+LP+P L+ T+ YL + L+ + QFR+++A+ K F G+G+ L LL ++Q Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLL--ERQE 79 Query: 107 KHTSYISGPWF-DMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKT 165 K +++S W DMYL R ++ +N +P + F + NDQL RF Sbjct: 80 KTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQL-----------RFAAC 128 Query: 166 LQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFNSTR 225 L +G+L ++K L+ W L + PL M QY+RLF+S R Sbjct: 129 LISGVL---------------SYKTLLDSHSLPTDWAKGQL-SGQPLCMKQYYRLFSSYR 172 Query: 226 IPRPNRDELFTDTKA-----RHLLVLRKGHFYVFDVLDQ-----DGNIVNPLEIQAHLKY 275 +P +D L + H++V F+V DV+ +G++ +++ +K Sbjct: 173 LPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFT--QLRKIVKM 230 Query: 276 ILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDDFPMKD 334 ++ +P P+ LTS+ R WA+ R L+ D N ++L ++ + +CLD + Sbjct: 231 ASNEDERLP--PIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGE 288 Query: 335 L--IHLSHTMLHG-----DGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNEV 387 L H + +LHG +G NRW+DKS +V DGT V EHS DG+ +++ + Sbjct: 289 LSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 348 Query: 388 FRDSTQTPAITPQSQPAATNSSASV---ETLSFNLSGALKAGITAAKEKFDTTVKTLSID 444 + +T + +S + + L + S + + ++ EK VK L Sbjct: 349 LKH-----MMTSNKKLVRADSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFI 403 Query: 445 SIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRP 504 +F GK F+KK++ SPD Q+A Q+A+ R Y + V TYES S F+ GR + IR Sbjct: 404 VYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRS 463 Query: 505 AS----IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALR 560 A+ F + ++ P+ + LQ M ++Y T A G D HL ALR Sbjct: 464 ATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEY----TVMAITGMAIDNHLLALR 519 Query: 561 YLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDW 620 LA PE+++D Y N +LSTS + + + PVVP+G+G Y + Sbjct: 520 ELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQPEA 579 Query: 621 IGCNVSSYSG---RNAREFLHCVQKCLEDIFD 649 I +SS+ ++ EF V L D+ D Sbjct: 580 ITFCISSFHSCKETSSVEFAEAVGASLVDMRD 611 >1XMD-A nrPDB Length = 612 Score = 241 bits (616), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 182/606 (30%), Positives = 288/606 (47%), Gaps = 56/606 (9%) Query: 42 TMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLA 101 T YQDSLP LP+P LE+++K+YL + KP ++ ++++TE + + F+ G GK LH LL Sbjct: 13 TFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLE 72 Query: 102 QDKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAV 160 + + + +++ W ++ YL R LN N P P E+ T L ++ Sbjct: 73 RARGKR--NWLEEWWLNVAYLDVRIPSQLNVN---FVGPCPHFEHYWPAREGTQLERGSM 127 Query: 161 RFLKTLQA-GLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 219 L LL E ++ S + PLDM+Q+ Sbjct: 128 MLWHNLNYWQLLRREKLPVHKSGNT--------------------------PLDMNQFRM 161 Query: 220 LFNSTRIPRPNRDELFTDTKAR-------HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAH 272 LF++ ++P RD + K H+ VL +G +VFDVL +G ++ P E+ Sbjct: 162 LFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL-HEGCLITPPELLRQ 220 Query: 273 LKYILSDSSPVPEFP-VAYLTSENRDVWAELRQKLI-FD-GNEETLKKVDSAVFCLCLDD 329 L YI S P P +A LTSE R WA+ R+ LI D N L+K+ +++F ++D Sbjct: 221 LTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIED 280 Query: 330 ----FPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFN 385 ++ + +L GD + RW DKS+NLI +G +H+ D + V+ + Sbjct: 281 SSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAH 340 Query: 386 EVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDS 445 V +T S+ E L F + + ++ AK + L I + Sbjct: 341 YVDERVLETEGRWKGSE--KVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAA 398 Query: 446 IQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPA 505 F GK+ K++ L PD QLA Q+A+ R +G+ YE+ T F HGRTET+R Sbjct: 399 STFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSC 458 Query: 506 SIFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATA 565 ++ R ++ ++DPS S+ E Q M E H ++ K+ + G+GFDRHL L +A Sbjct: 459 TVEAVRWCQS-MQDPSA-SLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKE 516 Query: 566 RGLNLPELYLDPAYQQMNHN---ILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIG 622 GL +PEL+ DP + + +LSTS + V G P+V +G+G Y + DD Sbjct: 517 EGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDRFV 575 Query: 623 CNVSSY 628 SS+ Sbjct: 576 VACSSW 581 >6BVE-A nrPDB Length = 245 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 29/134 (21%), Positives = 54/134 (40%), Gaps = 12/134 (8%) Query: 56 KLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFE--TGVGKELHAHLLAQDKQNKHTSYIS 113 K + + +L KPL++D+ R LC F +G+ ++LH + QN H Sbjct: 17 KTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVRLGAQNVHWEASG 76 Query: 114 GPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLQAGLLEP 173 ++ I ++ ++ + +Y + NL R L +AGL+ Sbjct: 77 AYTGEISAAMLTEIGIH---YVVIGHSERRQYFGETDETANL-----RVLAAQKAGLI-- 126 Query: 174 EVFHLNPSKSDTDA 187 + + SK+ DA Sbjct: 127 PILCVGESKAQRDA 140 >1GE6-A nrPDB Length = 167 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 579 YQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDW 620 Y MN N S+ + + + G FA V P+ FG Y W Sbjct: 60 YTDMNSNDFSSYSFDCTCTAAGTFAYVYPNRFGTVYLCGAFW 101 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2FYO-A nrPDB 935 0.0 1T7N-A nrPDB 799 0.0 2FY4-A nrPDB 773 0.0 1T1U-A nrPDB 763 0.0 1S5O-A nrPDB 761 0.0 1XMD-A nrPDB 727 0.0 Sequences not found previously or not previously below threshold: 4ZCF-A nrPDB 33 0.54 1K3V-A nrPDB 31 2.5 CONVERGED! >2FYO-A nrPDB Length = 653 Score = 935 bits (2416), Expect = 0.0, Method: Composition-based stats. Identities = 632/632 (100%), Positives = 632/632 (100%) Query: 27 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN 86 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN Sbjct: 22 AVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKN 81 Query: 87 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN 146 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN Sbjct: 82 FETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYN 141 Query: 147 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL 206 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL Sbjct: 142 DQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYL 201 Query: 207 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP 266 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP Sbjct: 202 VNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNP 261 Query: 267 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC 326 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC Sbjct: 262 LEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLC 321 Query: 327 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE 386 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE Sbjct: 322 LDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE 381 Query: 387 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI 446 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI Sbjct: 382 VFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSI 441 Query: 447 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 506 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS Sbjct: 442 QFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 501 Query: 507 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR 566 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR Sbjct: 502 IFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATAR 561 Query: 567 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS 626 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS Sbjct: 562 GLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVS 621 Query: 627 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT 658 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT Sbjct: 622 SYSGRNAREFLHCVQKCLEDIFDALEGKAIKT 653 >1T7N-A nrPDB Length = 618 Score = 799 bits (2062), Expect = 0.0, Method: Composition-based stats. Identities = 197/633 (31%), Positives = 316/633 (49%), Gaps = 65/633 (10%) Query: 43 MHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLL 100 M +QD+LPRLP+P L+ ++ YL A +P++ + ++ T+ L F+T GVG+ L L Sbjct: 21 MAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGL- 79 Query: 101 AQDKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSA 159 + + K +++S W YL R +V+ +P + PK ++ D Sbjct: 80 -ERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVIL---PKQDFVD--------LQGQ 127 Query: 160 VRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 219 +RF L G+L+ FK +I + + G PL M+QY++ Sbjct: 128 LRFAAKLIEGVLD---------------FKSMIDNETLPVEFLGGQ-----PLCMNQYYQ 167 Query: 220 LFNSTRIPRPNRDELFTDTKAR----HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKY 275 + +S R+P P +D + K++ H+ V+ F+ DV DG + +I L+ Sbjct: 168 ILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEK 227 Query: 276 ILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDD--FPM 332 I + S + PV LTS +R+ WA+ LI D N E++ + ++F +CLD + Sbjct: 228 IWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRV 287 Query: 333 KDLIHLSH---TMLHGDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFF 384 D ++ +H MLHG G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ Sbjct: 288 SDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALV 347 Query: 385 NEVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSID 444 + V + + + P + L FN++ +K I AK+ ++ L I Sbjct: 348 DHVMEYTKKPELVRSPMVPL-----PMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIM 402 Query: 445 SIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRP 504 + F GK+F K ++LSPDA Q+A Q+A+ R YGQ ATYES S F GRT+TIR Sbjct: 403 MLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRS 462 Query: 505 ASIFTKRCSEAFVRDPSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLYALRYL 562 ASI S AFV+ +V E Q ++ + + H T A G+ FDRHL L+ Sbjct: 463 ASI----DSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQ 518 Query: 563 ATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIG 622 A +++P++++D +Y H LSTS + + +G F PVVPDG+GI Y + I Sbjct: 519 AIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVGFFGPVVPDGYGICYNPMEAHIN 578 Query: 623 CNVSSYSG---RNAREFLHCVQKCLEDIFDALE 652 +VS+Y+ NA H ++K L D+ L+ Sbjct: 579 FSVSAYNSCAETNAARMAHYLEKALLDMRTLLQ 611 >2FY4-A nrPDB Length = 612 Score = 773 bits (1997), Expect = 0.0, Method: Composition-based stats. Identities = 182/633 (28%), Positives = 298/633 (47%), Gaps = 70/633 (11%) Query: 46 QDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQD 103 + LP+LP+P L+ T+ YL + L+ + QFR+++A+ + F G+G+ L LL + Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLL--E 67 Query: 104 KQNKHTSYISGPWF-DMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRF 162 +Q K +++S W DMYL R ++ +N +P + F +DQL RF Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQL-----------RF 116 Query: 163 LKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFN 222 +L +G+L ++K L+ L + PL M QY+ LF+ Sbjct: 117 AASLISGVL---------------SYKALLDSHSIPTDCAKGQL-SGQPLCMKQYYGLFS 160 Query: 223 STRIPRPNRDELFTDTKA-----RHLLVLRKGHFYVFDVLDQ-----DGNIVNPLEIQAH 272 S R+P +D L + H++V F+V DV+ +G++ +++ Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFT--QLRKI 218 Query: 273 LKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDDFP 331 +K + ++ +P P+ LTS+ R WAE R L+ D N ++L ++ + +CLD Sbjct: 219 VKMASNAAARLP--PIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPG 276 Query: 332 MKD--LIHLSHTMLHG-----DGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFF 384 + H + +LHG +G NRW+DKS +V DGT V EHS DG+ +++ Sbjct: 277 GVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCT 336 Query: 385 NEVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSID 444 + + TQ + P + L + S ++ + ++ EK VK L Sbjct: 337 EHLLKHMTQPELVRSPMVPL-----PAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 391 Query: 445 SIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRP 504 +F GK F+KK++ SPDA Q+A Q+AF R + + V TYES S F+ GR + IR Sbjct: 392 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 451 Query: 505 ASIFTKRCSEAFVRDPSKHSVG----ELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALR 560 A+ AFVR + H E ++ + + T A G D HL ALR Sbjct: 452 ATPEA----LAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR 507 Query: 561 YLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDW 620 LA A LPE+++D Y N +LSTS + + + PVVP+G+G Y + Sbjct: 508 ELARAMCAALPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET 567 Query: 621 IGCNVSSYSG---RNAREFLHCVQKCLEDIFDA 650 I +SS+ ++ +F V++ L D+ D Sbjct: 568 ILFCISSFHSCAATSSSKFAKAVEESLIDMRDL 600 >1T1U-A nrPDB Length = 639 Score = 763 bits (1970), Expect = 0.0, Method: Composition-based stats. Identities = 182/637 (28%), Positives = 295/637 (46%), Gaps = 73/637 (11%) Query: 49 LPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQDKQN 106 LP+LP+P L+ T+ YL + L+ + QFR+++A+ K F G+G+ L LL ++Q Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLL--ERQE 79 Query: 107 KHTSYISGPWF-DMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKT 165 K +++S W DMYL R ++ +N +P + F + NDQL RF Sbjct: 80 KTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQL-----------RFAAC 128 Query: 166 LQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFNSTR 225 L +G+L ++K L+ W L + PL M QY+RLF+S R Sbjct: 129 LISGVL---------------SYKTLLDSHSLPTDWAKGQL-SGQPLCMKQYYRLFSSYR 172 Query: 226 IPRPNRDELFTDTKA-----RHLLVLRKGHFYVFDVLDQ-----DGNIVNPLEIQAHLKY 275 +P +D L + H++V F+V DV+ +G++ +++ +K Sbjct: 173 LPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFT--QLRKIVKM 230 Query: 276 ILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDDFPMKD 334 ++ +P P+ LTS+ R WA+ R L+ D N ++L ++ + +CLD + Sbjct: 231 ASNEDERLP--PIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGE 288 Query: 335 L--IHLSHTMLHG-----DGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNEV 387 L H + +LHG +G NRW+DKS +V DGT V EHS DG+ +++ + Sbjct: 289 LSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 348 Query: 388 FRDSTQTPAITPQSQPAATNSS---ASVETLSFNLSGALKAGITAAKEKFDTTVKTLSID 444 + +T + +S + L + S + + ++ EK VK L Sbjct: 349 LKHM-----MTSNKKLVRADSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFI 403 Query: 445 SIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRP 504 +F GK F+KK++ SPD Q+A Q+A+ R Y + V TYES S F+ GR + IR Sbjct: 404 VYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRS 463 Query: 505 ASIFTKRCSEAFVRDPSKHSVG----ELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALR 560 A+ AFV+ + H E ++ + + T A G D HL ALR Sbjct: 464 ATPEA----LAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEYTVMAITGMAIDNHLLALR 519 Query: 561 YLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDW 620 LA PE+++D Y N +LSTS + + + PVVP+G+G Y + Sbjct: 520 ELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQPEA 579 Query: 621 IGCNVSSYSG---RNAREFLHCVQKCLEDIFDALEGK 654 I +SS+ ++ EF V L D+ D + Sbjct: 580 ITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSR 616 >1S5O-A nrPDB Length = 616 Score = 761 bits (1964), Expect = 0.0, Method: Composition-based stats. Identities = 181/618 (29%), Positives = 301/618 (48%), Gaps = 65/618 (10%) Query: 58 EDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQDKQNKHTSYISGP 115 + ++ YL A +P++ + ++ T+ L F+ GVG+ L L + + K +++S Sbjct: 23 QQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGL--ERRARKTENWLSEW 80 Query: 116 WFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLQAGLLEPE 174 W YL R +V+ +P + PK ++ D +RF L G+L+ Sbjct: 81 WLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQLRFAAKLIEGVLD-- 127 Query: 175 VFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPRPNRDEL 234 FK +I + + G PL M+QY+++ +S R+P P +D + Sbjct: 128 -------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQILSSCRVPGPKQDTV 169 Query: 235 FTDTKAR----HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKYILSDSSPVPEFPVAY 290 +K + H+ V+ F+ DV DG + +I L+ I + S + PV Sbjct: 170 SNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGI 229 Query: 291 LTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLDD--FPMKDLIHLSH---TMLH 344 LTS +R+ WA+ LI D N ++++ + ++F +CLD + + ++ SH MLH Sbjct: 230 LTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLH 289 Query: 345 GDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNEVFRDSTQTPAITP 399 G G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ + V + + + Sbjct: 290 GGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRS 349 Query: 400 QSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSIQFQRGGKEFLKKK 459 P + L FN++ +K+ I AK+ ++ L I + F GK+F K + Sbjct: 350 PMVPL-----PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSE 404 Query: 460 QLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVRD 519 +LSPDA Q+A Q+A+ R YGQ ATYES S F GRT+TIR AS+ S FV+ Sbjct: 405 KLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASM----DSLTFVKA 460 Query: 520 PSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATARGLNLPELYLDP 577 SV E Q ++ + + H T A G+ FDRHL L+ A ++ P++++D Sbjct: 461 MDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDT 520 Query: 578 AYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSG---RNAR 634 +Y H LSTS + + + F PVVPDG+G+ Y + I ++S+Y+ NA Sbjct: 521 SYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAA 580 Query: 635 EFLHCVQKCLEDIFDALE 652 H ++K L D+ L+ Sbjct: 581 RLAHYLEKALLDMRALLQ 598 >1XMD-A nrPDB Length = 612 Score = 727 bits (1876), Expect = 0.0, Method: Composition-based stats. Identities = 183/632 (28%), Positives = 295/632 (46%), Gaps = 59/632 (9%) Query: 42 TMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLA 101 T YQDSLP LP+P LE+++K+YL + KP ++ ++++TE + + F+ G GK LH LL Sbjct: 13 TFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLE 72 Query: 102 QDKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAV 160 + + + +++ W ++ YL R LN N P P E+ T L ++ Sbjct: 73 RARGKR--NWLEEWWLNVAYLDVRIPSQLNVN---FVGPCPHFEHYWPAREGTQLERGSM 127 Query: 161 RFLKTLQA-GLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 219 L LL E ++ S + PLDM+Q+ Sbjct: 128 MLWHNLNYWQLLRREKLPVHKSGNT--------------------------PLDMNQFRM 161 Query: 220 LFNSTRIPRPNRDELFTDTKAR-------HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAH 272 LF++ ++P RD + K H+ VL +G +VFDVL +G ++ P E+ Sbjct: 162 LFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLH-EGCLITPPELLRQ 220 Query: 273 LKYILSDSSPVPEFP-VAYLTSENRDVWAELRQKLIF--DGNEETLKKVDSAVFCLCLDD 329 L YI S P P +A LTSE R WA+ R+ LI N L+K+ +++F ++D Sbjct: 221 LTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIED 280 Query: 330 ----FPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFN 385 ++ + +L GD + RW DKS+NLI +G +H+ D + V+ + Sbjct: 281 SSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAH 340 Query: 386 EVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDS 445 V +T S+ E L F + + ++ AK + L I + Sbjct: 341 YVDERVLETEGRWKGSE--KVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAA 398 Query: 446 IQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPA 505 F GK+ K++ L PD QLA Q+A+ R +G+ YE+ T F HGRTET+R Sbjct: 399 STFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSC 458 Query: 506 SIFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATA 565 ++ R ++ ++DPS S+ E Q M E H ++ K+ + G+GFDRHL L +A Sbjct: 459 TVEAVRWCQS-MQDPSA-SLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKE 516 Query: 566 RGLNLPELYLDPAYQQMNH---NILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIG 622 GL +PEL+ DP + + +LSTS + V G P+V +G+G Y + DD Sbjct: 517 EGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDRFV 575 Query: 623 CNVSSYSG---RNAREFLHCVQKCLEDIFDAL 651 SS+ +A + + + D+ + Sbjct: 576 VACSSWRSCPETDAEKLVQMIFHAFHDMIQLM 607 >4ZCF-A nrPDB Length = 644 Score = 32.8 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 34/212 (16%), Positives = 58/212 (27%), Gaps = 25/212 (11%) Query: 64 YLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLAQDKQNKHTSYISG-----PWFD 118 Y ++ L+ + ++ + KN +G+E + + Q K+T + D Sbjct: 247 YTKNKEQLISE--WKSNISDVKNLLVNIGEEFASKYTGNELQEKYTQWFREHRSELWPLD 304 Query: 119 MYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSA----VRFLKTLQAGLLEPE 174 Y D + NP + D + T RF LL E Sbjct: 305 RY-KYIDKDGIYTGSQSVHNPGKEGYRYDIIHPKTKKPCKQPLMGYRFPLDTMDRLLSEE 363 Query: 175 VFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLD----MSQYFRLFNSTRIPRPN 230 ++ K + Y L + LD ++ LF P N Sbjct: 364 KIIFGDDENKIIELKVYAKD-------YKQKLSSVIHLDGRVATNELKELFPEMTQPFTN 416 Query: 231 RDELFTDTKARHLLVLRKGHFYVFDVLDQDGN 262 + + G V D G Sbjct: 417 AKTI--KLVEDLISFACDGEGIVLDFFAGSGT 446 >1K3V-A nrPDB Length = 579 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 35/83 (42%), Gaps = 17/83 (20%) Query: 26 SAVSGP----DDYLQHSIVPTMHYQDSLPRLPIPKLEDTM-------------KRYLNAQ 68 SA S P ++ L S++ + ++LP P +T+ + YL+ Sbjct: 156 SATSPPTKIYNNDLTASLMVALDTNNTLPYTPAAPRSETLGFYPWLPTKPTQYRYYLSCI 215 Query: 69 KPLLDDSQFRRTEALCKNFETGV 91 + L + +++ + + +TG+ Sbjct: 216 RNLNPPTYTGQSQQITDSIQTGL 238 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.124 0.325 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,765,957 Number of Sequences: 36641 Number of extensions: 889258 Number of successful extensions: 2341 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 2230 Number of HSP's gapped (non-prelim): 21 length of query: 658 length of database: 10,336,785 effective HSP length: 103 effective length of query: 555 effective length of database: 6,562,762 effective search space: 3642332910 effective search space used: 3642332910 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)