BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P18440 (290 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IJA-A nrPDB 600 e-172 2PFR-A nrPDB 468 e-132 2BSZ-A nrPDB 125 2e-29 4NV8-A nrPDB 123 1e-28 3D9W-A nrPDB 105 2e-23 1GX3-A nrPDB 103 7e-23 4BGF-A nrPDB 91 8e-19 4B55-A nrPDB 87 9e-18 1W4T-A nrPDB 80 8e-16 4GUZ-A nrPDB 69 2e-12 4DMO-A nrPDB 67 1e-11 1E2T-A nrPDB 66 2e-11 3LNB-A nrPDB 66 2e-11 6A4I-A nrPDB 32 0.39 6QVC-B nrPDB 28 3.3 >2IJA-A nrPDB Length = 295 Score = 600 bits (1548), Expect = e-172, Method: Compositional matrix adjust. Identities = 288/289 (99%), Positives = 288/289 (99%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR Sbjct: 7 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 66 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV Sbjct: 67 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 126 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 DAG GRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL Sbjct: 127 DAGSGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 186 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 241 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH Sbjct: 187 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 246 Query: 242 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 290 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI Sbjct: 247 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 295 >2PFR-A nrPDB Length = 294 Score = 468 bits (1204), Expect = e-132, Method: Compositional matrix adjust. Identities = 234/289 (80%), Positives = 256/289 (88%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 DIEAY ERIGYK SRNKLDLETLTDIL+HQIRAVPFENLN+HCG AM+LGLEAIFD +VR Sbjct: 6 DIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVR 65 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RNRGGWCLQVN LLYWALTTIGF+TTMLGGY Y P KYSTGM+HLLLQVTIDGRNYIV Sbjct: 66 RNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIV 125 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 DAG G S QMWQPLELISGKDQPQVPC+F LTEE G WYLDQIRREQYI N+EFL+S LL Sbjct: 126 DAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLL 185 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 241 K++KIY FTL+PRTIEDFESMNTYLQTSP+S F + SFCSLQTP+GV+CLVGF LT+ Sbjct: 186 PKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTY 245 Query: 242 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 290 R+FNYKDNTDL+EFKTL+EEE+E+VLKNIF ISL R LVPK GD TI Sbjct: 246 RKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI 294 >2BSZ-A nrPDB Length = 278 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 81/239 (33%), Positives = 118/239 (49%), Gaps = 19/239 (7%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 D++AYL RIGY RN L+TL + +A+PFEN++ G + L L A+ D++V Sbjct: 8 DLDAYLARIGYTGPRNA-SLDTLKALHFAHPQAIPFENIDPFLGRPVRLDLAALQDKIVL 66 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RGG+C + N L AL +GFE L V ++ T H+LL+V +DGR YI Sbjct: 67 GGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQSEDAITARSHMLLRVELDGRTYIA 126 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 D GFG + PL L G++Q FR+ E + D R + I + Sbjct: 127 DVGFG-GLTLTAPLLLEPGREQKTPHEPFRIVEAD-----DHFRLQAAIGGD-------- 172 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT 240 +R +Y F L+P+ D+ N +L TSP+S F S + PD + L G L+ Sbjct: 173 ----WRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLS 227 >4NV8-A nrPDB Length = 312 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 83/260 (31%), Positives = 126/260 (48%), Gaps = 20/260 (7%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 D++AYL RIGY RN L+TL + +A+P+EN++ G + L L A+ D++V Sbjct: 42 DLDAYLARIGYTGPRNA-SLDTLKALHFAHPQAIPWENIDPFLGRPVRLDLAALQDKIVL 100 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RGG+C + N L AL +GFE L V ++ T H+LL+V +DGR YI Sbjct: 101 GGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQSEDAITARSHMLLRVELDGRTYIA 160 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 D GFG + PL L G++Q FR+ E + D R + I + Sbjct: 161 DVGFG-GLTLTAPLLLEPGREQKTPHEPFRIVEAD-----DHFRLQAAIGGD-------- 206 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT- 240 +R +Y F L+P+ D+ N +L TSP+S F S + PD + L G L+ Sbjct: 207 ----WRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSI 262 Query: 241 HRRFNYKDNTDLIEFKTLSE 260 H + T++ L++ Sbjct: 263 HHLGGRTEQTEIATAADLAD 282 >3D9W-A nrPDB Length = 293 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 87/286 (30%), Positives = 125/286 (43%), Gaps = 41/286 (14%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 +D++AYL RIG+ R L TL +++ A+PFENL G + L L + D++V Sbjct: 16 LDLDAYLARIGFAGERAPT-LATLRELVYRHTTAIPFENLEAVLGRPVRLDLATLQDKLV 74 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTI--DGRN 118 RGG+C + L AL +GF T G V T H LL+VT D R Sbjct: 75 HSRRGGYCYENAGLFAAALERLGFGVTGHTGRV--TMGAGGLRPATHALLRVTTADDDRV 132 Query: 119 YIVDAGFGRSYQMWQPLELISGKDQPQVPCV----FRLTEENG-----FWYLDQIRREQY 169 ++ D GFGR PL + QP + FRL G W L Q R+ + Sbjct: 133 WMCDVGFGRG-----PLRPYELRPQPDEFTLGDWRFRLERRTGELGTDLWVLHQFGRDGW 187 Query: 170 IPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPD 229 + Y+FT P+ DFE N ++ TSP S FT++ F D Sbjct: 188 VDR-----------------YTFTTAPQYRIDFEVGNHFVSTSPRSPFTTRPFLQRFHSD 230 Query: 230 GVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISL 275 H L G TL R + + + L+ E+ +V+ +F+I L Sbjct: 231 RHHVLDGLTLITERPDGS-----ADIRALTPGELPEVINELFDIEL 271 >1GX3-A nrPDB Length = 284 Score = 103 bits (258), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 88/279 (31%), Positives = 124/279 (44%), Gaps = 28/279 (10%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCG-DAMDLGLEAIFDQV 59 MD+ YL RIG R + DL TL I+ R++PFENL+ G DL EA+F ++ Sbjct: 12 MDLGGYLTRIGLD-GRPRPDLGTLHAIVAAHNRSIPFENLDPLLGIPVADLSAEALFAKL 70 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYS-TGMIHLLLQVTIDGRN 118 V R RGG+C + N LL + L +GFE L G V A H +L V + G + Sbjct: 71 VDRRRGGYCYEHNGLLGYVLEELGFEVERLSGRVVWMRADDAPLPAQTHNVLSVAVPGAD 130 Query: 119 --YIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG + P+ L +G Q +RLT L R ++ P Sbjct: 131 GRYLVDVGFG-GQTLTSPIRLEAGPVQQTRHEPYRLTRHGDDHTLAAQVRGEWQP----- 184 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 +Y+FT +PR D E + Y+ T P S F + ++ T D + L G Sbjct: 185 ------------LYTFTTEPRPRIDLEVGSWYVSTHPGSHFVTGLTVAVVTDDARYNLRG 232 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISL 275 L R T+ I F S ++ + N F I L Sbjct: 233 RNLAVHR---SGATEHIRFD--SAAQVLDAIVNRFGIDL 266 >4BGF-A nrPDB Length = 283 Score = 90.5 bits (223), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 73/278 (26%), Positives = 120/278 (43%), Gaps = 23/278 (8%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMD-LGLEAIFDQV 59 +D+ AY +RI Y+ + + L+ L D++ R +PFENL+ G +D L +A+ D++ Sbjct: 3 LDLTAYFDRINYRGATDPT-LDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKL 61 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGG-YVYSTPAKKYSTGMIHLLLQVTIDGRN 118 V R RGG+C + N L+ + L +G+ V+ H LL VT G Sbjct: 62 VLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSG 121 Query: 119 --YIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG PL L +G QP +RL + + L + R+ Sbjct: 122 GCYLVDVGFGGQTPT-SPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRD--------- 171 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 ++ +Y FT + R D + + Y T P+S F + ++ T D L G Sbjct: 172 --------TWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSG 223 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNIS 274 L R + L + + + E+ N+ +I Sbjct: 224 RDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIG 261 >4B55-A nrPDB Length = 283 Score = 87.0 bits (214), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 111/248 (44%), Gaps = 24/248 (9%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMD-LGLEAIFDQV 59 +D+ YL+RI Y+ + + L+ L D++ A+ FENL+ G +D L EA+ D++ Sbjct: 6 LDLTGYLDRINYRGATDPT-LDVLRDLVSAHTGAIAFENLDPLMGVPVDDLSAEALADKL 64 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGG-YVYSTPAKKYSTGMIHLLLQVTIDG-- 116 V R RGG+C + N L+ + L +G+ L G V+ P + H +L VT G Sbjct: 65 VDRRRGGYCYEHNGLIGYVLAELGYRVRRLAGRVVWLAPPDAPTPAQTHTVLAVTFPGCQ 124 Query: 117 RNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG PL L +G Q +RL + L + R++ Sbjct: 125 GPYLVDVGFG-GMTPTAPLRLETGTVQQTALEPYRLDDRGDGLVLQAMVRDE-------- 175 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 ++ +Y F+ R D + ++ T P+S F + + D L+G Sbjct: 176 ---------WQALYEFSTLTRPQVDLRVGSWFVSTHPTSHFVTGLMAATVADDARWNLMG 226 Query: 237 FTLT-HRR 243 L HRR Sbjct: 227 RNLAIHRR 234 >1W4T-A nrPDB Length = 299 Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 73/275 (26%), Positives = 121/275 (44%), Gaps = 29/275 (10%) Query: 5 AYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNR 64 AYL IG L L ++ +R V FENL++ +++ + +F +VV +R Sbjct: 31 AYLHHIGIDDP-GPPSLANLDRLIDAHLRRVAFENLDVLLDRPIEIDADKVFAKVVEGSR 89 Query: 65 GGWCLQVNHLLYWALTTIGFETTMLGGYV-YSTPAKKYSTGMIHLLLQVTIDGRNYIVDA 123 GG+C ++N L L +G+E +L V + P T HL+L++ + ++VD Sbjct: 90 GGYCFELNSLFARLLLALGYELELLVARVRWGLPDDAPLTQQSHLMLRLYLAEGEFLVDV 149 Query: 124 GFGRSYQMWQPLELISGK-DQPQVPCVFRLTEENGFWYLDQIR-REQYIPNEEFLHSDLL 181 GFG S + L L + D QV CV RL + + Y +R R ++P Sbjct: 150 GFG-SANPPRALPLPGDEADAGQVHCV-RLVDPHAGLYESAVRGRSGWLP---------- 197 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 241 +Y F L+P+ D+ N Y T P SVF ++ D + TL Sbjct: 198 -------LYRFDLRPQLWIDYIPRNWYTSTHPHSVFRQGLKAAITEGD-----LRLTLAD 245 Query: 242 RRFNYK-DNTDLIEFKTLSEEEIEKVLKNIFNISL 275 F + N + ++ + EE+ +L+ F + L Sbjct: 246 GLFGQRAGNGETLQRQLRDVEELLDILQTRFRLRL 280 >4GUZ-A nrPDB Length = 284 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 129/281 (45%), Gaps = 30/281 (10%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 + ++ YL IG+ R+ LETL + + + + +ENL+ + L + A+ +++ Sbjct: 13 LQLDEYLAFIGFDGDRSP-TLETLRRLQRGHVLNIKWENLDAVLHKHVALDIPAVQAKLL 71 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVY--STPAKKYSTGMIHLLLQVTIDGRN 118 R RGG+C + L L +GF+ + G V +T + + GM L V + Sbjct: 72 RSPRGGYCYEHVALFGAVLQRLGFDFYGIQGRVQMGATTIRPATHGM----LVVRLAAEQ 127 Query: 119 YIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEE-FLH 177 ++ D GFG S PL I D+ V +E+ + ++RR + P + + Sbjct: 128 WLCDVGFGTS-----PLAPIRLVDEAVV------ADES---WTYRLRRGEVTPGADGWTL 173 Query: 178 SDLLEDSK---YRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCL 234 S+ D + ++F L+P+ D+ + + ++ +SP S F++++F +PD H Sbjct: 174 SEAAGDGSEPGWLSRHTFVLEPQYPIDYRAASYFVASSPHSPFSTRAFVQQISPD--HA- 230 Query: 235 VGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISL 275 + L HR + + + L+ E+ L+ IF I L Sbjct: 231 --YILDHRELHEIQPGVGRKTRQLTPAEVLATLREIFGIEL 269 >4DMO-A nrPDB Length = 265 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 55/229 (24%), Positives = 104/229 (45%), Gaps = 11/229 (4%) Query: 14 KSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNH 73 + ++ + E L++I+ + VPFENLNI + ++ E + ++++ NRGG C ++N Sbjct: 17 EEKDTVSFEDLSNIMYAMAQTVPFENLNILEKNFKEISKENLKEKILVNNRGGLCYELNP 76 Query: 74 LLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQ 133 +Y+ L GF+ ++ G VY+ ++ H+ +T Y+++ GFG SY Sbjct: 77 TMYYFLKDSGFDVHLVSGTVYNAANSIWAVDSGHIATVLTHHNELYLIEVGFG-SYLPLA 135 Query: 134 PLELISGKDQPQVPCVFRLTEE--NGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYS 191 P+ + G+ +R+ +E Y+ ++R+ N EFL +D + Y+ Sbjct: 136 PVPFL-GEVIHSATGDYRIRKEMTEKGNYILEMRK-----NNEFLDQSAADD--WTLGYA 187 Query: 192 FTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT 240 F ++ E + + S F T DG L +LT Sbjct: 188 FYIEEVDEEKANTAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLT 236 >1E2T-A nrPDB Length = 284 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 21/198 (10%) Query: 34 AVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFET-TMLGGY 92 A+PFENL++ + L A+ ++++ RGG+C ++N L AL IGF ++LG Sbjct: 38 AIPFENLDVLLPREIQLDETALEEKLLYARRGGYCFELNGLFERALRDIGFNVRSLLGRV 97 Query: 93 VYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRL 152 + S PA H LL V ++ +I D GFG + PL L + Q +RL Sbjct: 98 ILSHPASL--PPRTHRLLLVDVEDEQWIADVGFG-GQTLTAPLRLQAEIAQQTPHGEYRL 154 Query: 153 TEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTS 212 +E W L Q R ++ ++ +Y F L + D N + Sbjct: 155 MQEGSTWIL-QFRHHEH----------------WQSMYCFDLGVQQQSDHVMGNFWSAHW 197 Query: 213 PSSVFTSKSFCSLQTPDG 230 P S F PDG Sbjct: 198 PQSHFRHHLLMCRHLPDG 215 >3LNB-A nrPDB Length = 309 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 49/177 (27%), Positives = 91/177 (51%), Gaps = 10/177 (5%) Query: 24 LTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIG 83 L +IL + +PFENL+I G ++ + ++++ + RGG C ++N LLY+ L G Sbjct: 55 LDEILLNMGMILPFENLDIMAGTIKNISKNNLVEKLLIQKRGGLCYELNSLLYYFLMDCG 114 Query: 84 FETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPL----ELIS 139 F+ + G VY K+ H+++ + + ++Y++DAGF S+ P+ E+IS Sbjct: 115 FQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDYVIDAGFA-SHLPLHPVPFSGEVIS 173 Query: 140 GKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKP 196 Q + + T + G L ++R+ + FL S+ +++ Y+FTL P Sbjct: 174 --SQTGEYRIRKRTTQKGTHIL-EMRKGANGESTNFLQSE--PSDEWKIGYAFTLDP 225 >6A4I-A nrPDB Length = 391 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 194 LKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLI 253 L+ T DF YL SP+S F S F L+ GV L + + R +Y+DN Sbjct: 135 LETMTALDFNDFREYL--SPASGFQSLQFRLLENKIGV--LQNMRVPYNRRHYRDNFKGE 190 Query: 254 EFKTLSEEEIEKVLKNIFNISLQRK--LVPKHGDRFF 288 E + L + E EK L + L+R L P HG F+ Sbjct: 191 ENELLLKSEQEKTLLELVEAWLERTPGLEP-HGFNFW 226 >6QVC-B nrPDB Length = 988 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 231 VHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIE 264 +HCL+G ++ +D+TDL++ +S EEIE Sbjct: 772 LHCLLGRARPTKKKTTQDSTDLVD--NMSPEEIE 803 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IJA-A nrPDB 419 e-118 2PFR-A nrPDB 381 e-106 4NV8-A nrPDB 288 3e-78 2BSZ-A nrPDB 286 8e-78 4BGF-A nrPDB 285 1e-77 1GX3-A nrPDB 283 8e-77 4B55-A nrPDB 280 7e-76 4GUZ-A nrPDB 256 7e-69 3D9W-A nrPDB 254 3e-68 4DMO-A nrPDB 234 3e-62 1W4T-A nrPDB 232 1e-61 3LNB-A nrPDB 219 1e-57 1E2T-A nrPDB 214 4e-56 Sequences not found previously or not previously below threshold: 3AZQ-A nrPDB 34 0.090 5V8F-8 nrPDB 32 0.23 1IK6-A nrPDB 31 0.48 1DE6-A nrPDB 27 9.7 CONVERGED! >2IJA-A nrPDB Length = 295 Score = 419 bits (1077), Expect = e-118, Method: Composition-based stats. Identities = 288/289 (99%), Positives = 288/289 (99%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR Sbjct: 7 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 66 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV Sbjct: 67 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 126 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 DAG GRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL Sbjct: 127 DAGSGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 186 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 241 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH Sbjct: 187 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 246 Query: 242 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 290 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI Sbjct: 247 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 295 >2PFR-A nrPDB Length = 294 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 234/289 (80%), Positives = 256/289 (88%) Query: 2 DIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVR 61 DIEAY ERIGYK SRNKLDLETLTDIL+HQIRAVPFENLN+HCG AM+LGLEAIFD +VR Sbjct: 6 DIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVR 65 Query: 62 RNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV 121 RNRGGWCLQVN LLYWALTTIGF+TTMLGGY Y P KYSTGM+HLLLQVTIDGRNYIV Sbjct: 66 RNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIV 125 Query: 122 DAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLL 181 DAG G S QMWQPLELISGKDQPQVPC+F LTEE G WYLDQIRREQYI N+EFL+S LL Sbjct: 126 DAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLL 185 Query: 182 EDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTH 241 K++KIY FTL+PRTIEDFESMNTYLQTSP+S F + SFCSLQTP+GV+CLVGF LT+ Sbjct: 186 PKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTY 245 Query: 242 RRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI 290 R+FNYKDNTDL+EFKTL+EEE+E+VLKNIF ISL R LVPK GD TI Sbjct: 246 RKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI 294 >4NV8-A nrPDB Length = 312 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 83/262 (31%), Positives = 126/262 (48%), Gaps = 20/262 (7%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 D++AYL RIGY RN L+TL + +A+P+EN++ G + L L A+ D++V Sbjct: 41 FDLDAYLARIGYTGPRNA-SLDTLKALHFAHPQAIPWENIDPFLGRPVRLDLAALQDKIV 99 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI 120 RGG+C + N L AL +GFE L V ++ T H+LL+V +DGR YI Sbjct: 100 LGGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQSEDAITARSHMLLRVELDGRTYI 159 Query: 121 VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL 180 D GFG + PL L G++Q FR+ E + D R + I + Sbjct: 160 ADVGFG-GLTLTAPLLLEPGREQKTPHEPFRIVEAD-----DHFRLQAAIGGD------- 206 Query: 181 LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT 240 +R +Y F L+P+ D+ N +L TSP+S F S + PD + L G L+ Sbjct: 207 -----WRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLS 261 Query: 241 -HRRFNYKDNTDLIEFKTLSEE 261 H + T++ L++ Sbjct: 262 IHHLGGRTEQTEIATAADLADT 283 >2BSZ-A nrPDB Length = 278 Score = 286 bits (731), Expect = 8e-78, Method: Composition-based stats. Identities = 84/262 (32%), Positives = 126/262 (48%), Gaps = 20/262 (7%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 D++AYL RIGY RN L+TL + +A+PFEN++ G + L L A+ D++V Sbjct: 7 FDLDAYLARIGYTGPRNA-SLDTLKALHFAHPQAIPFENIDPFLGRPVRLDLAALQDKIV 65 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI 120 RGG+C + N L AL +GFE L V ++ T H+LL+V +DGR YI Sbjct: 66 LGGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQSEDAITARSHMLLRVELDGRTYI 125 Query: 121 VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL 180 D GFG + PL L G++Q FR+ E + D R + I + Sbjct: 126 ADVGFG-GLTLTAPLLLEPGREQKTPHEPFRIVEAD-----DHFRLQAAIGGD------- 172 Query: 181 LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT 240 +R +Y F L+P+ D+ N +L TSP+S F S + PD + L G L+ Sbjct: 173 -----WRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLS 227 Query: 241 -HRRFNYKDNTDLIEFKTLSEE 261 H + T++ L++ Sbjct: 228 IHHLGGRTEQTEIATAADLADT 249 >4BGF-A nrPDB Length = 283 Score = 285 bits (729), Expect = 1e-77, Method: Composition-based stats. Identities = 73/278 (26%), Positives = 120/278 (43%), Gaps = 23/278 (8%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMD-LGLEAIFDQV 59 +D+ AY +RI Y+ + + L+ L D++ R +PFENL+ G +D L +A+ D++ Sbjct: 3 LDLTAYFDRINYRGATDPT-LDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKL 61 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYV-YSTPAKKYSTGMIHLLLQVTIDGRN 118 V R RGG+C + N L+ + L +G+ V + H LL VT G Sbjct: 62 VLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSG 121 Query: 119 --YIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG PL L +G QP +RL + + L + R+ Sbjct: 122 GCYLVDVGFG-GQTPTSPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRD--------- 171 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 ++ +Y FT + R D + + Y T P+S F + ++ T D L G Sbjct: 172 --------TWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSG 223 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNIS 274 L R + L + + + E+ N+ +I Sbjct: 224 RDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIG 261 >1GX3-A nrPDB Length = 284 Score = 283 bits (723), Expect = 8e-77, Method: Composition-based stats. Identities = 86/280 (30%), Positives = 124/280 (44%), Gaps = 28/280 (10%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAM-DLGLEAIFDQV 59 MD+ YL RIG R + DL TL I+ R++PFENL+ G + DL EA+F ++ Sbjct: 12 MDLGGYLTRIGLDG-RPRPDLGTLHAIVAAHNRSIPFENLDPLLGIPVADLSAEALFAKL 70 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYST-PAKKYSTGMIHLLLQVTIDGRN 118 V R RGG+C + N LL + L +GFE L G V H +L V + G + Sbjct: 71 VDRRRGGYCYEHNGLLGYVLEELGFEVERLSGRVVWMRADDAPLPAQTHNVLSVAVPGAD 130 Query: 119 --YIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG + P+ L +G Q +RLT L R + Sbjct: 131 GRYLVDVGFG-GQTLTSPIRLEAGPVQQTRHEPYRLTRHGDDHTLAAQVRGE-------- 181 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 ++ +Y+FT +PR D E + Y+ T P S F + ++ T D + L G Sbjct: 182 ---------WQPLYTFTTEPRPRIDLEVGSWYVSTHPGSHFVTGLTVAVVTDDARYNLRG 232 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQ 276 L R T+ I F S ++ + N F I L Sbjct: 233 RNLAVHR---SGATEHIRFD--SAAQVLDAIVNRFGIDLG 267 >4B55-A nrPDB Length = 283 Score = 280 bits (715), Expect = 7e-76, Method: Composition-based stats. Identities = 70/283 (24%), Positives = 122/283 (43%), Gaps = 23/283 (8%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMD-LGLEAIFDQV 59 +D+ YL+RI Y+ + + L+ L D++ A+ FENL+ G +D L EA+ D++ Sbjct: 6 LDLTGYLDRINYRGATDPT-LDVLRDLVSAHTGAIAFENLDPLMGVPVDDLSAEALADKL 64 Query: 60 VRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYST-PAKKYSTGMIHLLLQVTIDG-- 116 V R RGG+C + N L+ + L +G+ L G V P + H +L VT G Sbjct: 65 VDRRRGGYCYEHNGLIGYVLAELGYRVRRLAGRVVWLAPPDAPTPAQTHTVLAVTFPGCQ 124 Query: 117 RNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFL 176 Y+VD GFG PL L +G Q +RL + L + R++ Sbjct: 125 GPYLVDVGFG-GMTPTAPLRLETGTVQQTALEPYRLDDRGDGLVLQAMVRDE-------- 175 Query: 177 HSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 ++ +Y F+ R D + ++ T P+S F + + D L+G Sbjct: 176 ---------WQALYEFSTLTRPQVDLRVGSWFVSTHPTSHFVTGLMAATVADDARWNLMG 226 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKL 279 L R + L + + + ++ N+ ++ + +L Sbjct: 227 RNLAIHRRGGTEKILLEDAAAVVDTLGDRFGINVADVGERGRL 269 >4GUZ-A nrPDB Length = 284 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 64/280 (22%), Positives = 121/280 (43%), Gaps = 26/280 (9%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 + ++ YL IG+ R+ LETL + + + + +ENL+ + L + A+ +++ Sbjct: 13 LQLDEYLAFIGFDGDRSPT-LETLRRLQRGHVLNIKWENLDAVLHKHVALDIPAVQAKLL 71 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI 120 R RGG+C + L L +GF+ + G V H +L V + ++ Sbjct: 72 RSPRGGYCYEHVALFGAVLQRLGFDFYGIQGRVQMGATT--IRPATHGMLVVRLAAEQWL 129 Query: 121 VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEE-FLHSD 179 D GFG S PL I D+ V + ++RR + P + + S+ Sbjct: 130 CDVGFGTS-----PLAPIRLVDEAVV---------ADESWTYRLRRGEVTPGADGWTLSE 175 Query: 180 LLEDSK---YRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVG 236 D + ++F L+P+ D+ + + ++ +SP S F++++F +PD + Sbjct: 176 AAGDGSEPGWLSRHTFVLEPQYPIDYRAASYFVASSPHSPFSTRAFVQQISPDHAY---- 231 Query: 237 FTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQ 276 L HR + + + L+ E+ L+ IF I L Sbjct: 232 -ILDHRELHEIQPGVGRKTRQLTPAEVLATLREIFGIELG 270 >3D9W-A nrPDB Length = 293 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 87/286 (30%), Positives = 125/286 (43%), Gaps = 41/286 (14%) Query: 1 MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV 60 +D++AYL RIG+ R L TL +++ A+PFENL G + L L + D++V Sbjct: 16 LDLDAYLARIGFAGERAPT-LATLRELVYRHTTAIPFENLEAVLGRPVRLDLATLQDKLV 74 Query: 61 RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTI--DGRN 118 RGG+C + L AL +GF T G V T H LL+VT D R Sbjct: 75 HSRRGGYCYENAGLFAAALERLGFGVTGHTGRV--TMGAGGLRPATHALLRVTTADDDRV 132 Query: 119 YIVDAGFGRSYQMWQPLELISGKDQPQVPCV----FRLTEENG-----FWYLDQIRREQY 169 ++ D GFGR PL + QP + FRL G W L Q R+ + Sbjct: 133 WMCDVGFGRG-----PLRPYELRPQPDEFTLGDWRFRLERRTGELGTDLWVLHQFGRDGW 187 Query: 170 IPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPD 229 + Y+FT P+ DFE N ++ TSP S FT++ F D Sbjct: 188 VDR-----------------YTFTTAPQYRIDFEVGNHFVSTSPRSPFTTRPFLQRFHSD 230 Query: 230 GVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISL 275 H L G TL R + + + L+ E+ +V+ +F+I L Sbjct: 231 RHHVLDGLTLITERPDGS-----ADIRALTPGELPEVINELFDIEL 271 >4DMO-A nrPDB Length = 265 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 62/272 (22%), Positives = 122/272 (44%), Gaps = 18/272 (6%) Query: 6 YLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRG 65 + R+ + ++ + E L++I+ + VPFENLNI + ++ E + ++++ NRG Sbjct: 10 FFARLHI-EEKDTVSFEDLSNIMYAMAQTVPFENLNILEKNFKEISKENLKEKILVNNRG 68 Query: 66 GWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGF 125 G C ++N +Y+ L GF+ ++ G VY+ ++ H+ +T Y+++ GF Sbjct: 69 GLCYELNPTMYYFLKDSGFDVHLVSGTVYNAANSIWAVDSGHIATVLTHHNELYLIEVGF 128 Query: 126 GRSYQMWQPLELISGKDQPQVPCVFRLTEE--NGFWYLDQIRREQYIPNEEFLHSDLLED 183 G SY P+ + G+ +R+ +E Y+ ++R+ N EFL +D Sbjct: 129 G-SYLPLAPVPFL-GEVIHSATGDYRIRKEMTEKGNYILEMRK-----NNEFLDQSAADD 181 Query: 184 SKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRR 243 + Y+F ++ E + + S F T DG L +LT + Sbjct: 182 --WTLGYAFYIEEVDEEKANTAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVAK 239 Query: 244 FNYKDNTDLIEFKTLSEEEIEKVLKNIFNISL 275 K +T+++ + +L + F I+L Sbjct: 240 NGKKTK------ETVTDMQYTNLLHSKFGITL 265 >1W4T-A nrPDB Length = 299 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 72/274 (26%), Positives = 119/274 (43%), Gaps = 27/274 (9%) Query: 5 AYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNR 64 AYL IG L L ++ +R V FENL++ +++ + +F +VV +R Sbjct: 31 AYLHHIGIDDP-GPPSLANLDRLIDAHLRRVAFENLDVLLDRPIEIDADKVFAKVVEGSR 89 Query: 65 GGWCLQVNHLLYWALTTIGFETTMLGGYV-YSTPAKKYSTGMIHLLLQVTIDGRNYIVDA 123 GG+C ++N L L +G+E +L V + P T HL+L++ + ++VD Sbjct: 90 GGYCFELNSLFARLLLALGYELELLVARVRWGLPDDAPLTQQSHLMLRLYLAEGEFLVDV 149 Query: 124 GFGRSYQMWQPLELISGK-DQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLE 182 GFG S + L L + D QV CV RL + + Y +R Sbjct: 150 GFG-SANPPRALPLPGDEADAGQVHCV-RLVDPHAGLYESAVR----------------G 191 Query: 183 DSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHR 242 S + +Y F L+P+ D+ N Y T P SVF ++ D + TL Sbjct: 192 RSGWLPLYRFDLRPQLWIDYIPRNWYTSTHPHSVFRQGLKAAITEGD-----LRLTLADG 246 Query: 243 RFNYK-DNTDLIEFKTLSEEEIEKVLKNIFNISL 275 F + N + ++ + EE+ +L+ F + L Sbjct: 247 LFGQRAGNGETLQRQLRDVEELLDILQTRFRLRL 280 >3LNB-A nrPDB Length = 309 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 112/261 (42%), Gaps = 12/261 (4%) Query: 15 SRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHL 74 ++ L +IL + +PFENL+I G ++ + ++++ + RGG C ++N L Sbjct: 46 PAKEITFNDLDEILLNMGMILPFENLDIMAGTIKNISKNNLVEKLLIQKRGGLCYELNSL 105 Query: 75 LYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQP 134 LY+ L GF+ + G VY K+ H+++ + + ++Y++DAGF S+ P Sbjct: 106 LYYFLMDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDYVIDAGFA-SHLPLHP 164 Query: 135 LELISGK--DQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSF 192 + Q + + T + G L ++R+ + FL S+ +++ Y+F Sbjct: 165 VPFSGEVISSQTGEYRIRKRTTQKGTHIL-EMRKGANGESTNFLQSE--PSDEWKIGYAF 221 Query: 193 TLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDL 252 TL P + ++ + S F + T G L T F N Sbjct: 222 TLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYT-ETFKGTKNKRP 280 Query: 253 IEFKTLSEEEIEKVLKNIFNI 273 IE K + ++L+ F I Sbjct: 281 IESKDYA-----RILRESFGI 296 >1E2T-A nrPDB Length = 284 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 65/274 (23%), Positives = 107/274 (39%), Gaps = 25/274 (9%) Query: 3 IEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRR 62 + AY R+ + + +E L + A+PFENL++ + L A+ ++++ Sbjct: 8 LHAYFTRL-HCQPLGVPTVEALRTLHLAHNCAIPFENLDVLLPREIQLDETALEEKLLYA 66 Query: 63 NRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVD 122 RGG+C ++N L AL IGF L G V + H LL V ++ +I D Sbjct: 67 RRGGYCFELNGLFERALRDIGFNVRSLLGRVILSHP-ASLPPRTHRLLLVDVEDEQWIAD 125 Query: 123 AGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLE 182 GFG + PL L + Q +RL +E W L Q R ++ Sbjct: 126 VGFG-GQTLTAPLRLQAEIAQQTPHGEYRLMQEGSTWIL-QFRHHEH------------- 170 Query: 183 DSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHR 242 ++ +Y F L + D N + P S F PDG TLT+ Sbjct: 171 ---WQSMYCFDLGVQQQSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGG----KLTLTNF 223 Query: 243 RFNYKDNTDLIEFKTLSEEEIE-KVLKNIFNISL 275 F +E + + ++L+ F + + Sbjct: 224 HFTRYHQGHAVEQVNVPDVPSLYQLLQQQFGLGV 257 >3AZQ-A nrPDB Length = 662 Score = 33.6 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 28/171 (16%), Positives = 50/171 (29%), Gaps = 22/171 (12%) Query: 85 ETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIV----DAGFGRSYQMWQPLELISG 140 G+ ++ + LL T G + DA G + P+ + G Sbjct: 73 RVFEYSGFPWAGVPRPAGGP----LLVFTHFGDQRLYAFEPDAPGGAVPRPLTPVSAVGG 128 Query: 141 -------KDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKI---- 189 P+ V+ + EE +RR ++ S + S R++ Sbjct: 129 GLRWADPVLLPERGEVWCMAEEFTGEGPSDVRR--FLAAVPLDGSAAADRSAVRELSDDA 186 Query: 190 YSFTLKPRTIEDFESMNTYLQTSPSSVFT-SKSFCSLQTPDGVHCLVGFTL 239 + F PR D P + ++ + T DG L Sbjct: 187 HRFVTGPRLSPDGRQAVWLAWDHPRMPWEGTELKTARVTEDGRFADTRTLL 237 >5V8F-8 nrPDB Length = 604 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 21/54 (38%) Query: 173 EEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQ 226 F + LED + + Y F P+ D + N L + S +F F + Sbjct: 75 ANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQL 128 >1IK6-A nrPDB Length = 369 Score = 31.3 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 42/124 (33%), Gaps = 3/124 (2%) Query: 163 QIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFES-MNTYLQTSPSSVFTSKS 221 Q ++ +E L+ + Y L RT + Y SP ++F Sbjct: 129 QFVDFIWLGADELLNHIAKLRYRSGGNYKAPLVVRTPVGSGTRGGLYHSNSPEAIFVHTP 188 Query: 222 FCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVP 281 + P + G R + D +E K L E+V + + + + + V Sbjct: 189 GLVVVMPSTPYNAKGLLKAAIRGD--DPVVFLEPKILYRAPREEVPEGDYVVEIGKARVA 246 Query: 282 KHGD 285 + GD Sbjct: 247 REGD 250 >1DE6-A nrPDB Length = 426 Score = 27.0 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 20/155 (12%), Positives = 46/155 (29%), Gaps = 11/155 (7%) Query: 131 MWQPLELISGKDQPQVPCVFRLTE-----------ENGFWYLDQIRREQYIPNEEFLHSD 179 + Q + LI G + + ++ ++ W + + S Sbjct: 86 LEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSH 145 Query: 180 LLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTL 239 L + ++ + D + + + S ++ PDG+ + L Sbjct: 146 PLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRL 205 Query: 240 THRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNIS 274 R+ ++I K I+ V +F I Sbjct: 206 APRQRLLAALDEVISEKLNPAHHIDAVESKLFGIG 240 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.125 0.319 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,292,969 Number of Sequences: 36641 Number of extensions: 385984 Number of successful extensions: 1193 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 36 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1099 Number of HSP's gapped (non-prelim): 44 length of query: 290 length of database: 10,336,785 effective HSP length: 96 effective length of query: 194 effective length of database: 6,819,249 effective search space: 1322934306 effective search space used: 1322934306 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.0 bits)