BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P18291 (248 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FI8-A nrPDB 472 e-134 1IAU-A nrPDB 340 3e-94 3G01-A nrPDB 322 1e-88 3TK9-A nrPDB 296 6e-81 1EUF-A nrPDB 295 1e-80 1KYN-A nrPDB 259 7e-70 1NN6-A nrPDB 246 6e-66 3RP2-A nrPDB 218 2e-57 2RDL-A nrPDB 207 3e-54 1FUJ-A nrPDB 164 3e-41 1FDP-A nrPDB 164 3e-41 1ORF-A nrPDB 164 4e-41 1A0J-A nrPDB 160 5e-40 1MZD-A nrPDB 159 2e-39 5MS3-A nrPDB 156 7e-39 5FCR-A nrPDB 155 1e-38 1UTJ-A nrPDB 155 2e-38 4AN7-A nrPDB 154 4e-38 5FXL-A nrPDB 152 1e-37 4Q7Y-A nrPDB 151 2e-37 4WWY-A nrPDB 146 7e-36 2TLD-E nrPDB 144 4e-35 1NPM-A nrPDB 141 3e-34 1F7Z-A nrPDB 140 4e-34 2ZKS-A nrPDB 139 1e-33 5C67-A nrPDB 139 1e-33 1SGF-G nrPDB 137 4e-33 1ELT-A nrPDB 137 4e-33 4NFE-A nrPDB 136 1e-32 1AZZ-A nrPDB 134 3e-32 3BSQ-A nrPDB 133 5e-32 1BRU-P nrPDB 133 6e-32 1GVZ-A nrPDB 133 6e-32 2CGA-A nrPDB 133 7e-32 2V35-A nrPDB 133 7e-32 1SGF-A nrPDB 133 9e-32 6QHB-A nrPDB 132 1e-31 2EEK-A nrPDB 132 2e-31 3QUM-P nrPDB 129 8e-31 1SPJ-A nrPDB 129 1e-30 1AO5-A nrPDB 129 1e-30 4DGJ-A nrPDB 128 3e-30 1EKB-B nrPDB 127 3e-30 4H4F-A nrPDB 126 7e-30 4MPW-A nrPDB 125 1e-29 3W94-A nrPDB 125 2e-29 2PSX-A nrPDB 125 2e-29 1TON-A nrPDB 124 3e-29 1AE5-A nrPDB 124 4e-29 5ZFH-A nrPDB 124 4e-29 2BDH-A nrPDB 123 9e-29 5UGG-A nrPDB 120 5e-28 2R0L-A nrPDB 119 1e-27 1YC0-A nrPDB 119 1e-27 1PPF-E nrPDB 118 2e-27 1PYT-D nrPDB 118 2e-27 3LC3-A nrPDB 117 4e-27 1LTO-A nrPDB 117 6e-27 1FON-A nrPDB 117 6e-27 4DUR-A nrPDB 116 8e-27 3DFJ-A nrPDB 114 3e-26 1FXY-A nrPDB 114 3e-26 1X7A-C nrPDB 114 4e-26 3E0N-B nrPDB 112 1e-25 4GSO-A nrPDB 111 3e-25 2AIQ-A nrPDB 110 4e-25 5XW8-A nrPDB 108 2e-24 2F91-A nrPDB 108 2e-24 4E7N-A nrPDB 107 5e-24 1A5I-A nrPDB 107 6e-24 1BDA-A nrPDB 106 8e-24 1EQ9-A nrPDB 106 1e-23 3S9B-A nrPDB 105 2e-23 2QY0-B nrPDB 104 3e-23 1P57-B nrPDB 104 4e-23 1GPZ-A nrPDB 104 4e-23 1FIZ-A nrPDB 104 5e-23 3T2N-A nrPDB 103 5e-23 3S69-A nrPDB 103 6e-23 5TJX-A nrPDB 103 9e-23 1MD7-A nrPDB 102 1e-22 5GVT-A nrPDB 102 2e-22 1C5M-D nrPDB 101 3e-22 1FIW-A nrPDB 101 3e-22 6I44-A nrPDB 100 4e-22 5LPF-A nrPDB 100 6e-22 4XDE-A nrPDB 100 1e-21 1KIG-H nrPDB 97 5e-21 1OP0-A nrPDB 97 5e-21 2OLG-A nrPDB 97 7e-21 2XXL-A nrPDB 96 1e-20 3F6U-H nrPDB 96 1e-20 2OQ5-A nrPDB 96 2e-20 1SC8-U nrPDB 94 7e-20 1BQY-A nrPDB 93 9e-20 3P8G-A nrPDB 93 9e-20 2F83-A nrPDB 93 1e-19 2XRC-A nrPDB 92 1e-19 5O32-I nrPDB 92 2e-19 6AOD-C nrPDB 92 2e-19 4Z6A-H nrPDB 92 2e-19 2B9L-A nrPDB 92 2e-19 2JET-B nrPDB 91 4e-19 1SI5-H nrPDB 91 5e-19 1ZJK-A nrPDB 91 5e-19 1Q3X-A nrPDB 91 6e-19 5KWM-A nrPDB 89 2e-18 5LHN-A nrPDB 88 4e-18 3VGC-B nrPDB 87 5e-18 4IGD-A nrPDB 87 5e-18 4DJZ-B nrPDB 87 8e-18 2ASU-B nrPDB 87 9e-18 2PKA-B nrPDB 86 1e-17 2HLC-A nrPDB 84 4e-17 4IW4-E nrPDB 84 5e-17 4FXG-H nrPDB 84 7e-17 1YM0-A nrPDB 83 9e-17 3BEU-A nrPDB 83 1e-16 3I77-A nrPDB 82 2e-16 2FMJ-A nrPDB 82 2e-16 4KKD-A nrPDB 80 8e-16 4LK4-A nrPDB 80 1e-15 5XRF-A nrPDB 80 1e-15 3H7O-A nrPDB 79 2e-15 1ELV-A nrPDB 78 3e-15 1M9U-A nrPDB 77 5e-15 5UBM-A nrPDB 77 6e-15 4J1Y-A nrPDB 77 1e-14 3NXP-A nrPDB 75 2e-14 3K65-B nrPDB 75 3e-14 4NZQ-A nrPDB 75 3e-14 1MKW-K nrPDB 73 9e-14 1VR1-H nrPDB 73 1e-13 1EPT-B nrPDB 72 2e-13 1ETT-H nrPDB 72 3e-13 2OCV-B nrPDB 72 3e-13 6BQM-A nrPDB 70 9e-13 4BXW-A nrPDB 70 1e-12 5TO3-B nrPDB 70 1e-12 2KAI-A nrPDB 66 1e-11 4X0L-C nrPDB 66 2e-11 4WJG-C nrPDB 65 3e-11 2WIN-I nrPDB 64 5e-11 4F4O-C nrPDB 64 6e-11 1DLE-A nrPDB 64 7e-11 2OK5-A nrPDB 64 8e-11 1PQ7-A nrPDB 64 8e-11 3RU4-E nrPDB 60 1e-09 3H7T-A nrPDB 59 2e-09 1RIW-B nrPDB 57 1e-08 1BBR-H nrPDB 56 1e-08 1AKS-B nrPDB 54 7e-08 3F1S-B nrPDB 52 2e-07 3H5C-B nrPDB 52 3e-07 2JET-C nrPDB 52 3e-07 2I6S-A nrPDB 39 0.002 2HNT-F nrPDB 31 0.56 1K93-A nrPDB 30 1.4 1BBR-E nrPDB 29 1.7 1LQU-A nrPDB 29 1.8 1XFY-A nrPDB 29 1.8 2HNT-C nrPDB 28 3.6 6O7W-d nrPDB 28 3.9 5LAK-A nrPDB 28 3.9 2AMU-A nrPDB 27 8.3 5GW5-z nrPDB 27 9.6 1HUS-A nrPDB 27 9.8 >1FI8-A nrPDB Length = 228 Score = 472 bits (1215), Expect = e-134, Method: Compositional matrix adjust. Identities = 227/228 (99%), Positives = 227/228 (99%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 248 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 228 >1IAU-A nrPDB Length = 227 Score = 340 bits (873), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 160/227 (70%), Positives = 187/227 (82%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMAYL I D+ S K+CGGFLIR+DFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKS-LKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQE QQ IPV + IPHPAYN K SNDIMLL+L+ KAKR+ AV+PL LP +VKPG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 C VAGWG+ P+GK+S TLQEV++TVQED+KCES L++Y+D E+C GDP+IK+ SF Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGPLVC KVA GIVSYG+N+G PRA TKVS+F+ WIKKTMK+ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 226 >3G01-A nrPDB Length = 227 Score = 322 bits (824), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 151/226 (66%), Positives = 176/226 (77%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG+E PHSRPYMAY + + CGGFL+R+ FVLTAAHC G + VTLGAHNI Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K +E+ QQIIPV K IPHP YN SNDIMLLKL AKR+ AV+PLNLPRRN VKPG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 D CYVAGWGK+ P G++ TL EV+LTVQ+DQ CES ++ +++ANEIC GD KIK ASF Sbjct: 121 DECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASF 180 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 RGDSGGPLVCK+ AAGIVSYGQ DGS P+ FT+V +F+SWIKKTMK Sbjct: 181 RGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >3TK9-A nrPDB Length = 226 Score = 296 bits (758), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 141/227 (62%), Positives = 170/227 (74%), Gaps = 2/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMA++Q + E S K+CGG L+R+DFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKS-RKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQE+ QQ IPV + IPHPAYN K SN+IMLL+L+ KAK ++AV+PL LP +VKPG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG + M + TLQEV LTVQ+D +CE + +A EIC GDPK + F Sbjct: 120 QLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGPLVCK VA GI+SYG G+ P + KVS FL WIK+TMK+ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKR 225 >1EUF-A nrPDB Length = 227 Score = 295 bits (755), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 140/227 (61%), Positives = 171/227 (75%), Gaps = 2/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMA+L + S CGGFL+REDFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFL-LFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E+E+ QQ+IPV + IPHP YN +T++NDIMLLKL KA + V P+NLPR +VKPG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG+LG +D LQEV+L VQ ++KC + KNY +ICAGDP ++ SF Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYI-PFTQICAGDPSKRKNSF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 GDSGGPLVC VA GIVSYG+NDG+TP +T++S+FLSWI TM++ Sbjct: 179 SGDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMRR 225 >1KYN-A nrPDB Length = 235 Score = 259 bits (662), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 125/226 (55%), Positives = 164/226 (72%), Gaps = 3/226 (1%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E++PHSRPYMAYLQI +G +CGGFL+REDFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSP-AGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + +E QQ I + I HP YN +TI NDIMLL+L + +R+ V P+ LPR ++PG Sbjct: 60 QRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG++ M + +DTL+EV+L VQ D++C +Y D +IC GD + ++A+F Sbjct: 120 TLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSY-DPRRQICVGDRRERKAAF 177 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 +GDSGGPL+C VA GIVSYG++ G P FT+VS+FL WI+ TM+ Sbjct: 178 KGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMR 223 >1NN6-A nrPDB Length = 228 Score = 246 bits (629), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 119/228 (52%), Positives = 155/228 (67%), Gaps = 2/228 (0%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH 78 GEIIGG E KPHSRPYMAYL+I+ SK CGGFLIR +FVLTAAHC+G I VTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 NI E+E Q + V+K HP YN+ T+ +DIMLLKLK KA + AV L P + V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 139 PGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 PG +C VAGWG+ G + SDTLQEV+L + + Q C + FD ++C G+P+ ++ Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD--FDHNLQLCVGNPRKTKS 178 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 +F+GDSGGPL+C VA GIVSYG++D P FT++S + WI + ++ Sbjct: 179 AFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 226 >3RP2-A nrPDB Length = 224 Score = 218 bits (556), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 110/225 (48%), Positives = 144/225 (64%), Gaps = 2/225 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E+ PHSRPYMA+L I+ E CGGFLI FVLTAAHC G +I V LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 +++E QQ I V K I H +YNS +DIMLLKL+ K + + AV + LP + + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C+ AGWGK G S TL+EVEL + +++ C Y Y++ ++C G P RA+F Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDY--RYYEYKFQVCVGSPTTLRAAF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTM 245 GDSGGPL+C VA GIVSYG D P FT+VST++ WI + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVI 223 >2RDL-A nrPDB Length = 226 Score = 207 bits (527), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 100/228 (43%), Positives = 141/228 (61%), Gaps = 2/228 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E +PH+RPYMAYL+I+ + C GFLIR +FV+TAAHC+G I V LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K +E Q + V K PHP Y+ + + NDIMLLKLK KA + V L + ++ + PG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 VC GWG+ SDTLQEV++ + + Q C+ + F + ++C G+PK R + Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHF--EDFHQEPQLCVGNPKKIRNVY 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 248 +GDSGGPL+C +A GI SY + P FT++S + WI K ++++ Sbjct: 179 KGDSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILREN 226 >1FUJ-A nrPDB Length = 221 Score = 164 bits (416), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 92/233 (39%), Positives = 131/233 (56%), Gaps = 19/233 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKINVTLG 76 I+GGHEA+PHSRPYMA LQ M GS CGG LI FVLTAAHC +NV LG Sbjct: 1 IVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 AHN++ QE QQ V ++ + Y+++ NDI+L++L S A S++V + LP+++ Sbjct: 60 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 V G C GWG++G + LQE+ +TV +F + + IC P+ K Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV----------VTFFCRPHNICTFVPRRK 168 Query: 197 RASFRGDSGGPLVCKKVAAGI---VSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPL+C + GI V +G P FT+V+ ++ WI+ T++ Sbjct: 169 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1FDP-A nrPDB Length = 235 Score = 164 bits (416), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 90/237 (37%), Positives = 137/237 (57%), Gaps = 18/237 (7%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKINVT 74 G I+GG EA+ H+RPYMA +Q+ +G+ CGG L+ E +VL+AAHC + K+ V Sbjct: 6 GRILGGREAEAHARPYMASVQL----NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVL 61 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 LGAH++ + E +++ V++ +PHP TI +D++LL+L KA AV+PL R + Sbjct: 62 LGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVD 121 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKA---NEICAG 191 V PG +C VAGWG + G+ D+LQ V L V + C + + D A +CA Sbjct: 122 RDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNR--RTHHDGAITERLMCA- 178 Query: 192 DPKIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTM 245 +R S +GDSGGPLVC V G+V+ G + P +T+V+++ +WI + Sbjct: 179 -ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1ORF-A nrPDB Length = 234 Score = 164 bits (415), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 98/237 (41%), Positives = 140/237 (59%), Gaps = 17/237 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN-VTLGAHN 79 IIGG+E PHSRPYM L + C G LI +D+VLTAAHC+ +K + V LGAH+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 56 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 I +E +QI+ V K P+P Y+ T D+ LL+L KAK + V L+LP++ VKP Sbjct: 57 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKP 116 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD-----KANEICAGDPK 194 G +C VAGWG+ +SDTL+EVE+T+ + + C +N+++ N +CAG + Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCND--RNHYNFNPVIGMNMVCAGSLR 174 Query: 195 IKRASFRGDSGGPLVCKKVAAGIVSYG-QNDGSTPRA---FTKVS-TFLSWIKKTMK 246 R S GDSG PL+C+ V G+ S+G +N PR + +S L+WI T+K Sbjct: 175 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1A0J-A nrPDB Length = 223 Score = 160 bits (405), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 94/230 (40%), Positives = 124/230 (53%), Gaps = 11/230 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+E + +S Y A LQ SG CGG LI +V++AAHC S+I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E +Q I VK+I HP+YNS+ + NDIML+KL A +S V + LP G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSS--CASSG 113 Query: 141 DVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C V+GWG L G Y DTL+ ++L + C S +N CAG + + S Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQI-TSNMFCAGFMEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVS--YGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGP+VC G+VS YG + P +TKV + SWI TM Sbjct: 173 CQGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSS 222 >1MZD-A nrPDB Length = 240 Score = 159 bits (401), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 98/238 (41%), Positives = 134/238 (56%), Gaps = 17/238 (7%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-----GSKINVT 74 EIIGG E PHSRP+MA +Q Y G CGG LI +VLTAAHC G V Sbjct: 2 EIIGGKEVSPHSRPFMASIQ----YGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 57 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 LGAH++ + E +Q + + K IP S SNDIML+KL++ AK + VK L++ R Sbjct: 58 LGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSK 116 Query: 135 VKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCES---YLKNYFDKANEICA 190 ++ G C V GWG P + SDTL+EV +TV + C S Y + F + +CA Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 191 GDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVS-TFLSWIKKTM 245 GD K ++ S +GD+GGPL+CK V IVS G G + P +T ++ + +WIK + Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >5MS3-A nrPDB Length = 228 Score = 156 bits (395), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 91/234 (38%), Positives = 134/234 (57%), Gaps = 19/234 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK-CGGFLIREDFVLTAAHCSGSKINVTLGAHN 79 ++GGHE +PHS+P+ A L + G + CGG L+ ++VLTAAHC K V LG H+ Sbjct: 1 VLGGHECQPHSQPWQAAL-----FQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHS 55 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTI---SNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 ++ ++ +Q IPVV+ IPHP YNS + ++D+MLL+L+ +A S VKP++L Sbjct: 56 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHC-- 113 Query: 137 VKPGDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCE-SYLKNYFDKANEICAGDPK 194 +PG C V+GWG + P + DTL E+ + +KCE +Y D +CAG K Sbjct: 114 TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD--GMVCAGSSK 171 Query: 195 IKRASFRGDSGGPLVCKKVAAGIVSYGQND---GSTPRAFTKVSTFLSWIKKTM 245 + +GDSGGPLVC GI S+G + P +T + +L WIKK + Sbjct: 172 -GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >5FCR-A nrPDB Length = 234 Score = 155 bits (392), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 82/234 (35%), Positives = 128/234 (54%), Gaps = 19/234 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG EA H+RPYMA +Q+ +G+ CGG L+ E +VL+AAHC + V L Sbjct: 1 ILGGQEAAAHARPYMASVQV----NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH++ E ++ V ++PHP ++ +D++L KL A V+PL L + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKA---NEICAGD 192 +V+PG +C VAGWG + G+ D L ++ +++ C L+ Y D N +CA Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCN--LRTYHDGVVTINMMCA-- 172 Query: 193 PKIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKK 243 +R + RGDSG PLVC G+V++G +G P +T+VS++ WI+ Sbjct: 173 ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 >1UTJ-A nrPDB Length = 242 Score = 155 bits (391), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 91/247 (36%), Positives = 130/247 (52%), Gaps = 10/247 (4%) Query: 1 MKLLLLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFV 60 M L+ +L A TE +I+GG+E KP+S+P+ L SG CGG L+ E++V Sbjct: 1 MISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLN-----SGYHFCGGSLVNENWV 55 Query: 61 LTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 ++AAHC S++ V LG HNIK E +Q I ++I HP Y+S I NDIML+KL A Sbjct: 56 VSAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPAT 115 Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN 180 ++ V+P+ LP G +C V+GWG S+ LQ + + + C + Sbjct: 116 LNTYVQPVALPTSCAPA--GTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG 173 Query: 181 YFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVS--YGQNDGSTPRAFTKVSTFL 238 A CAG + + S +GDSGGP+VC G+VS YG + P + KV F Sbjct: 174 MITNA-MFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFN 232 Query: 239 SWIKKTM 245 W+ TM Sbjct: 233 DWLTSTM 239 >4AN7-A nrPDB Length = 231 Score = 154 bits (388), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 92/235 (39%), Positives = 125/235 (53%), Gaps = 11/235 (4%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + +I+GG+ +S PY L SGS CGG LI +V++AAHC S+I V Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSLN-----SGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V ++LPR Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 134 NVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 G C ++GWG G Y LQ ++ V D C+S N IC G Sbjct: 117 --CAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQI-TGNMICVGF 173 Query: 193 PKIKRASFRGDSGGPLVCKKVAAGIVS--YGQNDGSTPRAFTKVSTFLSWIKKTM 245 + + S +GDSGGP+VC GIVS YG + P +TKV +++WI++T+ Sbjct: 174 LEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 228 >5FXL-A nrPDB Length = 246 Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 94/247 (38%), Positives = 133/247 (53%), Gaps = 12/247 (4%) Query: 3 LLLLLLSFSLA-PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVL 61 + L LL ++A P + +I+GG+ ++ PY L SG CGG LI +V+ Sbjct: 5 IFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLN-----SGYHFCGGSLINSQWVV 59 Query: 62 TAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKR 121 +AAHC S I V LG NI E +Q I K I HP+YNS T++NDIML+KLKS A Sbjct: 60 SAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASL 119 Query: 122 SSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKN 180 +S V ++LP G C ++GWG G Y D L+ ++ + D C+S Sbjct: 120 NSRVASISLPTS--CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG 177 Query: 181 YFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFL 238 +N CAG + + S +GDSGGP+VC GIVS+G + P +TKV ++ Sbjct: 178 QI-TSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYV 236 Query: 239 SWIKKTM 245 SWIK+T+ Sbjct: 237 SWIKQTI 243 >4Q7Y-A nrPDB Length = 250 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 91/238 (38%), Positives = 125/238 (52%), Gaps = 16/238 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN----VTLG 76 IIGGHE PHSRPYMA ++ + G CGGFL+R +V++AAHC + V LG Sbjct: 1 IIGGHEVTPHSRPYMASVR----FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP-RRNV 135 AH + E QQ+ + + HP Y+ T +NDI LL+L A AV L LP RR Sbjct: 57 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRAR 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEIC--AGDP 193 G C VAGWG + + L E ++ V + C S K + +C +GD Sbjct: 117 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 175 Query: 194 KIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 248 +R DSGGPLVC+ A G+VS+ D TP +T+VS F++WI +++S Sbjct: 176 H-RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 232 >4WWY-A nrPDB Length = 224 Score = 146 bits (369), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 89/230 (38%), Positives = 124/230 (53%), Gaps = 15/230 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ + +S PY L SG CGG LI E +V++A HC S+I V LG HNI Sbjct: 1 IVGGYNCEENSVPYQVSLN-----SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + E +Q I KII HP Y+ KT++NDIML+KL S+A ++ V ++LP G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLP--TAPPATG 113 Query: 141 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D LQ ++ V KCE+ +N C G + + S Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFLEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDGST----PRAFTKVSTFLSWIKKTM 245 + DSGGP+VC G+VS+G DG P +TKV ++ WIK T+ Sbjct: 173 CQRDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKVYNYVKWIKNTI 220 >2TLD-E nrPDB Length = 220 Score = 144 bits (363), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 89/227 (39%), Positives = 121/227 (53%), Gaps = 12/227 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ ++ PY L SG CGG LI +V++AAHC S I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSLN-----SGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E +Q I K I HP+YNS T++NDIML+KLKS A +S V ++LP G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTS--CASAG 113 Query: 141 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D L+ ++ + D C+S +N CAG S Sbjct: 114 TQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TSNMFCAGLE--GGDS 170 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG-STPRAFTKVSTFLSWIKKTM 245 +GDSGGP+VC GIVS+G + P +TKV ++SWIK+T+ Sbjct: 171 CQGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTI 217 >1NPM-A nrPDB Length = 225 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 87/235 (37%), Positives = 131/235 (55%), Gaps = 21/235 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK-CGGFLIREDFVLTAAHCSGSKINVTLGAHN 79 I+ G E PHS+P+ A L + G + CGG L+ + +VLTAAHC K +V LG H+ Sbjct: 1 ILEGRECIPHSQPWQAAL-----FQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHS 55 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNS---KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 ++ +++ +Q I V + I HP YN+ + S+DIML++L++ A VKP+ L N+ Sbjct: 56 LQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLC 113 Query: 137 VKPGDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANE--ICAGDP 193 K G C ++GWG + P + +TL E+ + KCE + Y K E +CAG Sbjct: 114 PKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCE---RAYPGKITEGMVCAGSS 170 Query: 194 KIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 + +GDSGGPLVC + GI S+G + P +TK+ + +WIKKTM Sbjct: 171 N-GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1F7Z-A nrPDB Length = 233 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 87/239 (36%), Positives = 124/239 (51%), Gaps = 13/239 (5%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + I+GG+ + +S PY L SG CGG LI + +V++AAHC S+I V Sbjct: 4 PVDDDDAIVGGYTCQENSVPYQVSLN-----SGYHFCGGSLINDQWVVSAAHCYKSRIQV 58 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q + KII HP ++ KT++NDIML+KL S K ++ V + LP Sbjct: 59 RLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 134 NVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCE-SYLKNYFDKANEICAG 191 G C ++GWG G D LQ ++ + CE SY D N +C G Sbjct: 119 CAPA--GTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITD--NMVCVG 174 Query: 192 DPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + + S +GDSGGP+VC GIVS+G P +TKV ++ WI+ T+ + Sbjct: 175 FLEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >2ZKS-A nrPDB Length = 240 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 88/238 (36%), Positives = 123/238 (51%), Gaps = 17/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG---SKINVTLGA 77 IIGG E PHSRPYMA LQ +GS CGG L+ +VLTAAHC +++ + LG Sbjct: 1 IIGGREVIPHSRPYMASLQ----RNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 H + I ++ HP Y + ND+ LL+L K K S ++PL LP + Sbjct: 57 HTLDSPGLTFHIKAAIQ---HPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQV 113 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-ESYLKNYFDKANEICAGDPKI 195 V G C +AGWG G+ S L+E++L V + + C S N + +C Sbjct: 114 VAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 173 Query: 196 KRASFRGDSGGPLVCKK--VAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 248 +A +GDSGGPLVC K V AG++S+ D P T V+ ++SWI+K +S Sbjct: 174 DQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >5C67-A nrPDB Length = 224 Score = 139 bits (349), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 84/228 (36%), Positives = 121/228 (53%), Gaps = 11/228 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ + +S PY L SGS CGG LI E +V++AAHC ++I V LG HNI Sbjct: 1 IVGGYTCEENSLPYQVSLN-----SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K E +Q I KII HP YN T+ NDIML+KL S A ++ V ++LP G Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP--TAPPAAG 113 Query: 141 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D L+ ++ V +C++ + C G + + S Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNS-MFCVGFLEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 + D+GGP+VC G+VS+G + P +TKV ++ WIK T+ Sbjct: 173 CQRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >1SGF-G nrPDB Length = 237 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 128/245 (52%), Gaps = 26/245 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG + + +S+P+ + +Y CGG L+ ++VLTAAHC V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQY----LCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V K IPHP +N + SND+MLL+L A + VKP+ Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANE- 187 LP K+ G C +GWG + P +++D L V L + ++ C K + +K + Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCA---KAHIEKVTDA 171 Query: 188 -ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKK 243 +CAG+ + + +GDSGGPL+C V GI S+G + P +TK++ F SWIK Sbjct: 172 MLCAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKD 231 Query: 244 TMKKS 248 TM K+ Sbjct: 232 TMAKN 236 >1ELT-A nrPDB Length = 236 Score = 137 bits (345), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 83/240 (34%), Positives = 121/240 (50%), Gaps = 19/240 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 ++GG A+P+S P+ LQ S CGG LIR+ +V+TAAHC S V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISN--DIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 N+ E +QI+ V + H +NS ++ DI LL+L ++A +SAV+ LP N Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD---KANEICAGDP 193 + + CY+ GWGK G SD+L++ L + C S ++ K +CAG Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSS--SGWWGSTVKTTMVCAGGG 178 Query: 194 KIKRASFRGDSGGPLVCK--------KVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTM 245 + GDSGGPL C+ V + + S G N P FT+VS ++SW+ M Sbjct: 179 --ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >4NFE-A nrPDB Length = 237 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 88/242 (36%), Positives = 119/242 (49%), Gaps = 26/242 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ Q+ G CGG L+ +VLTAAHC V LG HN+ Sbjct: 1 IVGGWECEKHSQPW----QVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 E E Q +PV PHP YN + S+D+MLL+L AK + VK L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGKYSD-TLQEVELTVQEDQKCESYLKNYFDKANE- 187 LP + + G CY +GWG + P +LQ V L + + C + Y +K E Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA---RAYSEKVTEF 171 Query: 188 -ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKK 243 +CAG + + GDSGGPLVC V GI S+G + P +TKV + WIK Sbjct: 172 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 231 Query: 244 TM 245 T+ Sbjct: 232 TI 233 >1AZZ-A nrPDB Length = 226 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 87/233 (37%), Positives = 119/233 (51%), Gaps = 23/233 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG EA P+S P+ A L I D Y CGG LI +++LTAAHC ++V LGAH Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMY----FCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 NI+E E Q I H YNS ISNDI +++L ++A+ + LP +V V Sbjct: 57 NIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV- 115 Query: 139 PGDVCYVAGWG-----KLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 G V GWG LG SD L++V++ + + C++ D IC D Sbjct: 116 -GTVVTPTGWGLPSDSALG----ISDVLRQVDVPIMSNADCDAVYGIVTD--GNICI-DS 167 Query: 194 KIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG---STPRAFTKVSTFLSWIKK 243 + + GDSGGPL + GI S+G G P AFT+V+ FL WI+ Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQT 220 >3BSQ-A nrPDB Length = 227 Score = 133 bits (335), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 85/231 (36%), Positives = 121/231 (52%), Gaps = 15/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSK-KCGGFLIREDFVLTAAHCSGSKINVTLGAHN 79 II G S P+ L SG++ CGG L+ E +VLTAAHC ++ V LG+ Sbjct: 1 IIDGAPCARGSHPWQVAL-----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 55 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + ++ Q I K HP Y+++T ND+ML+KL S+A+ SS VK + LP R P Sbjct: 56 LGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--EPP 111 Query: 140 GDVCYVAGWG-KLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G C V+GWG P + L V++ + Q C K+ + + +CAG P K+ Sbjct: 112 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKN 170 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMK 246 + GDSGGPLVC+ G+VS+G + P +T+V F WI TMK Sbjct: 171 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1BRU-P nrPDB Length = 241 Score = 133 bits (335), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 85/243 (34%), Positives = 120/243 (49%), Gaps = 17/243 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 ++GG +A+P+S P+ LQ CGG L+ + +VLTAAHC S V LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTIS--NDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 ++ E + V K++ H +NS +S NDI LLKL S + ++ LP Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE--SYLKNYFDKANEICAGDPK 194 + VCYV GWG+L G D LQ+ +L V + C + + K N ICAG Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTV-KTNMICAGGDG 179 Query: 195 IKRASFRGDSGGPLVCKKVAA-----GIVSYGQNDGST----PRAFTKVSTFLSWIKKTM 245 I +S GDSGGPL C+ GIVS+G + G P FT+VS ++ WI + Sbjct: 180 II-SSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 Query: 246 KKS 248 + Sbjct: 239 ANN 241 >1GVZ-A nrPDB Length = 237 Score = 133 bits (335), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 126/245 (51%), Gaps = 26/245 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + HS+P+ Q+ + G +CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPW----QVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYN-----------SKTISNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V P ++ IS+D+MLL+L A+ + AVK L+ Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESYLKNYFDKANE- 187 LP + K+ G CY +GWG + + S TLQ VEL +Q ++KC + Y +K E Sbjct: 117 LPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCA---RAYPEKMTEF 171 Query: 188 -ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKK 243 +CA + GDSGG L+C V GI S+G + D + FTKV WIK+ Sbjct: 172 VLCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKE 231 Query: 244 TMKKS 248 T++K+ Sbjct: 232 TIEKN 236 >2CGA-A nrPDB Length = 245 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 85/239 (35%), Positives = 125/239 (52%), Gaps = 24/239 (10%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH- 78 I+ G EA P S P+ LQ + +G CGG LI E++V+TAAHC + +V + Sbjct: 15 RIVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEF 71 Query: 79 -NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 EK+Q++ + K+ + YNS TI+NDI LLKL + A S V + LP + Sbjct: 72 DQGSSSEKIQKL-KIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 130 Query: 138 KPGDVCYVAGWGKLGPMGKYS-----DTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 G C GWG + +Y+ D LQ+ L + + C+ Y A ICAG Sbjct: 131 AAGTTCVTTGWG----LTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDA-MICAGA 185 Query: 193 PKIKRASFRGDSGGPLVCKKVAA----GIVSYGQN--DGSTPRAFTKVSTFLSWIKKTM 245 + +S GDSGGPLVCKK A GIVS+G + STP + +V+ ++W+++T+ Sbjct: 186 SGV--SSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 242 >2V35-A nrPDB Length = 240 Score = 133 bits (334), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 80/243 (32%), Positives = 126/243 (51%), Gaps = 18/243 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN--VTLGAH 78 ++GG EA+ +S P LQ S + CGG LIR+++V+TAAHC ++ V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISN--DIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 N+ + + +Q + V KI+ HP +N+ ++ DI LL+L +S V+ LPR Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD---KANEICAGDP 193 + CY+ GWG G+ + TLQ+ L + C S +Y+ K + +CAG Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSS--SSYWGSTVKNSMVCAGGD 178 Query: 194 KIKRASFRGDSGGPLVC----KKVAAGIVSY----GQNDGSTPRAFTKVSTFLSWIKKTM 245 + R+ +GDSGGPL C + G+ S+ G N P FT+VS ++SWI + Sbjct: 179 GV-RSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 Query: 246 KKS 248 + Sbjct: 238 ASN 240 >1SGF-A nrPDB Length = 240 Score = 133 bits (334), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 121/241 (50%), Gaps = 36/241 (14%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQI 89 +S+P+ + ++Y +CGG L+ ++VLTAAHC K V LG +N E E Q Sbjct: 13 NSQPWHVAVYRFNKY----QCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQH 68 Query: 90 IPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 V K IPHP +N + SND+MLL+L A + VKP+ LP K+ Sbjct: 69 RLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL- 127 Query: 139 PGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANE-------ICA 190 G C +GWG P+ KY D LQ V L + ++ C DKA+E +CA Sbjct: 128 -GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDC--------DKAHEMKVTDAMLCA 178 Query: 191 GDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTMKK 247 G+ + DSGGPL+C + GI S+G + + P +TK+ F SWI++TM Sbjct: 179 GEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMAN 238 Query: 248 S 248 + Sbjct: 239 N 239 >6QHB-A nrPDB Length = 223 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 83/219 (37%), Positives = 118/219 (53%), Gaps = 11/219 (5%) Query: 31 SRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQII 90 S PY A L SG CGG LI +VLTAAHC + V LG HN+ +QE Q+ Sbjct: 11 SHPYQAALYT----SGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQS 66 Query: 91 PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGK 150 VV+ + HP Y++ + DIMLL+L AK S ++PL L R+ + C++ GWGK Sbjct: 67 SVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL-ERDCSAQTTS-CHILGWGK 124 Query: 151 LGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC 210 G + DT+Q + + ++CE + N +CAGD K + S +GDSGGPLVC Sbjct: 125 TAD-GDFPDTIQCAYIHLVSREECEHAYPGQITQ-NMLCAGDEKYGKDSCQGDSGGPLVC 182 Query: 211 KKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMK 246 G+VS+G P +T V + +WI+KT++ Sbjct: 183 GDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >2EEK-A nrPDB Length = 220 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 79/227 (34%), Positives = 114/227 (50%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+E HS+ + L SG CGG L+ +D+V++AAHC S + V LG H+I Sbjct: 1 IVGGYECTKHSQAHQVSLN-----SGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + E +Q I +I HP Y+S I+NDIML+KL A + V + LP Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTE--CAADA 113 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C V+GWG D LQ + L + C + ++ CAG + + S Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQS-MFCAGYLEGGKDSC 172 Query: 201 RGDSGGPLVCKKVAAGIVS--YGQNDGSTPRAFTKVSTFLSWIKKTM 245 +GDSGGP+VC V G+VS YG + P + KV W++ TM Sbjct: 173 QGDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >3QUM-P nrPDB Length = 237 Score = 129 bits (325), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 82/240 (34%), Positives = 119/240 (49%), Gaps = 22/240 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ Q++ G CGG L+ +VLTAAHC +K + LG H++ Sbjct: 1 IVGGWECEKHSQPW----QVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISN-----------DIMLLKLKSKAKRSSAVKPLN 129 E Q+ V PHP Y+ + N D+MLL+L A+ + AVK ++ Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGKYS-DTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + + G CY +GWG + P + LQ V+L V + C K + Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM-L 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 CAG +++ GDSGGPLVC V GI S+G + P +TKV + WIK T+ Sbjct: 174 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >1SPJ-A nrPDB Length = 238 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 123/246 (50%), Gaps = 27/246 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ A L + +CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTF----QCGGILVHRQWVLTAAHCISDNYQLWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISN-----------DIMLLKLKSKAKR-SSAVKPL 128 + E Q + V + PHP +N + N D+MLL+L A + AVK + Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANE 187 LP +V G C +GWG + P + D LQ V+L + + +C+ K + K + Sbjct: 117 ELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECK---KAHVQKVTD 171 Query: 188 --ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIK 242 +C G + + + GDSGGPL+C V G+ S+G TP +V +++ WI+ Sbjct: 172 FMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIE 231 Query: 243 KTMKKS 248 T+ ++ Sbjct: 232 DTIAEN 237 >1AO5-A nrPDB Length = 237 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 82/245 (33%), Positives = 123/245 (50%), Gaps = 26/245 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG + +S+P+ Q+ Y CGG L+ ++VLTAAHC + V LG + + Sbjct: 1 VVGGFNCEKNSQPW----QVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 ++E Q V K PHP +N + S+D+MLL+L A + VKP+ Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + + KPG C +GWG + P + D LQ V +T+ ++ C K Y K ++ Sbjct: 117 LPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA---KVYLQKVTDV 171 Query: 189 --CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKK 243 CAG+ + + R DSGGPL+C + G SYG P +T + F SWIK Sbjct: 172 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 231 Query: 244 TMKKS 248 TM K+ Sbjct: 232 TMMKN 236 >4DGJ-A nrPDB Length = 235 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 75/239 (31%), Positives = 123/239 (51%), Gaps = 19/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC------SGSKINVT 74 I+GG +AK + P++ L Y CG L+ D++++AAHC SK Sbjct: 1 IVGGSDAKEGAWPWVVGLY----YDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 75 LGAHNIKEQEKMQQIIP--VVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 LG H +K Q +P + +I+ +P YN + NDI ++ L+ K + ++P++LP Sbjct: 57 LGLH-MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPE 115 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 N PG C +AGWG + G +D LQE ++ + +++C+ + Y N ICAG Sbjct: 116 ENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY 175 Query: 193 PKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 + S +GDSGGPL+C++ AG+ S+G + P + +VS F WI+ + Sbjct: 176 EEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQSFL 234 >1EKB-B nrPDB Length = 235 Score = 127 bits (320), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 124/240 (51%), Gaps = 21/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC------SGSKINVT 74 I+GG +++ + P++ L D+ + CG L+ D++++AAHC SK Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQ----QVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 75 LGAH---NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP 131 LG H N+ + ++I + I PH YN + +NDI ++ L+ K + ++P+ LP Sbjct: 57 LGLHMASNLTSPQIETRLIDQIVINPH--YNKRRKNNDIAMMHLEMKVNYTDYIQPICLP 114 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG 191 N PG +C +AGWG L G +D LQE ++ + ++KC+ + Y N +CAG Sbjct: 115 EENQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAG 174 Query: 192 DPKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 S +GDSGGPL+C++ + AG+ S+G + P + +V F WI+ + Sbjct: 175 YEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFL 234 >4H4F-A nrPDB Length = 249 Score = 126 bits (317), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 119/239 (49%), Gaps = 14/239 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 ++GG +A+PHS P+ LQ + + CGG LI +FVLTAAHC + V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 NIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 N++ E E+ + V I H +N+ + NDI L+KL + S ++ LP ++ + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 138 KPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKIK 196 CYV GWG+L G +D LQ+ V + C + K +CAG + Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 180 Query: 197 RASFRGDSGGPLVCK-----KVAAGIVSYGQNDGSTPR----AFTKVSTFLSWIKKTMK 246 A GDSGGPL C+ GIVS+G G R +T+VS ++ WI + M+ Sbjct: 181 SAC-NGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >4MPW-A nrPDB Length = 245 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 130/247 (52%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG EA P+ L++ Y CGG LI +VLTAAHC G + L A + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRV 58 Query: 81 KEQEK----MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + +E+ Q++PV +II HP + + I DI LL+L+ K SS V + LP + Sbjct: 59 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASET 118 Query: 137 VKPGDVCYVAGWGKLGPMGKYSD--TLQEVELTVQEDQKCES--YLKNY------FDKAN 186 PG C+V GWG + + L++V++ + E+ C++ +L Y + + Sbjct: 119 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 178 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQN--DGSTPRAFTKVSTFLSW 240 +CAG+ +R S +GDSGGPLVCK + AG+VS+G+ + P +T+V+ +L W Sbjct: 179 MLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 236 Query: 241 IKKTMKK 247 I + K Sbjct: 237 IHHYVPK 243 >3W94-A nrPDB Length = 235 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 78/239 (32%), Positives = 118/239 (49%), Gaps = 17/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK------INVT 74 ++GG A+ + P+M L + G CG LI D++LTAAHC K + Sbjct: 1 VVGGVNAEKGAWPWMVSLH----WRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 75 LGAHNIKEQEKMQ-QIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG H + QI V +II + YN +T DI ++ L+ + V P+ L Sbjct: 57 LGLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASE 116 Query: 134 NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 + G C++AGWG+ G D LQE E+ + + +C+ L Y ++ +CAG P Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYP 176 Query: 194 KIKRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMK 246 + S +GDSGGPL+C + A G+ S+G G P A+ +VS F SWI +T + Sbjct: 177 EGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAETRR 235 >2PSX-A nrPDB Length = 227 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 12/231 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G + H++P+ A L + CG L+ ++LTAAHC V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPN---QLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSL 57 Query: 81 KE-QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 E QQ+ VK IPHP Y+ SND+ML+KL + + + V+P+N+ Sbjct: 58 SPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA-- 115 Query: 140 GDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G C V+GWG P + LQ + ++V ++CE D CAGD K R Sbjct: 116 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDT-MFCAGD-KAGRD 173 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTMK 246 S +GDSGGP+VC G+VS+G + P +T + F WI++T++ Sbjct: 174 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >1TON-A nrPDB Length = 235 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 85/244 (34%), Positives = 126/244 (51%), Gaps = 26/244 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG++ + +S+P+ + +++EY CGG LI +V+TAAHC + V LG +N+ Sbjct: 1 IVGGYKCEKNSQPWQ--VAVINEY----LCGGVLIDPSWVITAAHCYSNNYQVLLGRNNL 54 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V + HP Y + SND+MLL L A + VK ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKC-ESYLKNYFDKANE 187 LP + KV G C +GWG P S LQ V + + ++KC E+Y N D Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVM-- 170 Query: 188 ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGS---TPRAFTKVSTFLSWIKKT 244 +CAG+ + + + GDSGGPL+C V GI S G + TP + K+ F SWIKK Sbjct: 171 LCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKV 230 Query: 245 MKKS 248 MK++ Sbjct: 231 MKEN 234 >1AE5-A nrPDB Length = 225 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 18/232 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK----INVTLG 76 I+GG +A+P P++A +Q G CGG LI FV+TAA C S+ V LG Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 A++++ +E+ + + + Y+ + ND+MLL+L +A +S+V L LP +N Sbjct: 57 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 V+ G C VAGWG G+ S + V +TV + +C + N +C G + Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRR 167 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYGQND-GSTPRAFTKVSTFLSWIKKTMKK 247 GD G PLVC+ +A G+ S+ G P FT+V+ F WI + Sbjct: 168 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 219 >5ZFH-A nrPDB Length = 224 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 80/230 (34%), Positives = 116/230 (50%), Gaps = 13/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G++ K S P+ L ++ CGG L+ + +VLTAAHC + V LG+ I Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQL----HCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKI 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 +Q Q I K HP Y++KT NDIML++L K SS V+ + LP PG Sbjct: 57 GDQSA--QKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEP--PG 112 Query: 141 DVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C V+GWG P + L ++ + ++C+ K+ K +CAG P K + Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKT-MLCAGIPDSKTNT 171 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPLVC G+VS+G + P +T+V + W+ +TMK Sbjct: 172 CNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >2BDH-A nrPDB Length = 223 Score = 123 bits (308), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 122/230 (53%), Gaps = 12/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G + PHS+P+ A L + +E C G L+ +VL+AAHC + + LG H++ Sbjct: 1 IINGEDCSPHSQPWQAALVMENEL----FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 56 Query: 81 K-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + +QE Q++ + HP YN ++ND+ML+KL S ++ +++ + Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-- 114 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 G+ C V+GWG L G+ LQ V ++V ++ C S L + + CAG + ++ S Sbjct: 115 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVC-SKLYDPLYHPSMFCAGGGQDQKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPL+C G+VS+G+ P +T + F WI+KT++ Sbjct: 173 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >5UGG-A nrPDB Length = 251 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 88/250 (35%), Positives = 121/250 (48%), Gaps = 24/250 (9%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 + PK G ++GG A PHS P+ L+ G CGG LI ++VLTAAHC Sbjct: 13 VEPKKCPGRVVGGCVAHPHSWPWQVSLRTR---FGMHFCGGTLISPEWVLTAAHCLEKSP 69 Query: 67 SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVK 126 S V LGAH E Q I V ++ P DI LLKL S A + V Sbjct: 70 RPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVI 123 Query: 127 PLNLPRRNVKVKPGDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDK 184 P LP N V C++ GWG+ G G + L+E +L V E++ C Y N + Sbjct: 124 PACLPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQ 181 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFL 238 + E+CAG S +GDSGGPLVC K + G+ S+G + P + +VS F+ Sbjct: 182 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFV 241 Query: 239 SWIKKTMKKS 248 +WI+ M+ + Sbjct: 242 TWIEGVMRNN 251 >2R0L-A nrPDB Length = 248 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 121/244 (49%), Gaps = 23/244 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 IIGG + P S P++A + I D + C G L+ +V++AAHC ++V L Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDSF-----CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISN-DIMLLKLKSK----AKRSSAVKPLNL 130 G H + Q + K IP+ Y+ S+ D++L++LK K A RS V+P+ L Sbjct: 56 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 115 Query: 131 PRRNVKVKPGDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFD-KANEI 188 P G C +AGWG L + YS +L+E + + D KC S D N + Sbjct: 116 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 175 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAA----GIVSYGQNDG--STPRAFTKVSTFLSWIK 242 CAG K + +GDSGGPL C+K GI+S+G G P +T+V+ ++ WI Sbjct: 176 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 235 Query: 243 KTMK 246 ++ Sbjct: 236 DRIR 239 >1YC0-A nrPDB Length = 283 Score = 119 bits (297), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 121/245 (49%), Gaps = 23/245 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVT 74 IIGG + P S P++A + I D + C G L+ +V++AAHC ++V Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDSF-----CAGSLVHTCWVVSAAHCFSHSPPRDSVSVV 89 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISN-DIMLLKLKSK----AKRSSAVKPLN 129 LG H + Q + K IP+ Y+ S+ D++L++LK K A RS V+P+ Sbjct: 90 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 149 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFD-KANE 187 LP G C +AGWG L + YS +L+E + + D KC S D N Sbjct: 150 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 209 Query: 188 ICAGDPKIKRASFRGDSGGPLVCKKVAA----GIVSYGQNDG--STPRAFTKVSTFLSWI 241 +CAG K + +GDSGGPL C+K GI+S+G G P +T+V+ ++ WI Sbjct: 210 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 269 Query: 242 KKTMK 246 ++ Sbjct: 270 NDRIR 274 >1PPF-E nrPDB Length = 218 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 113/233 (48%), Gaps = 22/233 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVT----LG 76 I+GG A+PH+ P+M LQ+ G CG LI +FV++AAHC + LG Sbjct: 1 IVGGRRARPHAWPFMVSLQL----RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 AHN+ +E +Q+ V +I + Y+ + NDI++L+L A ++ V+ LP + + Sbjct: 57 AHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 115 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 + G C GWG LG + LQE+ +TV + + +C + Sbjct: 116 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS----------LCRRSNVCTLVRGRQ 165 Query: 197 RASFRGDSGGPLVCKKVAAGIVSY---GQNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSG PLVC + GI S+ G G P AF V+ F++WI ++ Sbjct: 166 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1PYT-D nrPDB Length = 251 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/243 (31%), Positives = 118/243 (48%), Gaps = 17/243 (6%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN--VTL 75 + ++GG +A PHS P+ LQ + + + CGG LI + VLTAAHC + + V L Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVAL 70 Query: 76 GAHNIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 G +N++ E E + V I H +NS + NDI L+KL + ++ LP Sbjct: 71 GKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEG 130 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD---KANEICAG 191 + C+V GWG+L G + LQ+ V + C ++++ K +CAG Sbjct: 131 SLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQ--RDWWGTTVKETMVCAG 188 Query: 192 DPKIKRASFRGDSGGPLVCKKVAA----GIVSYGQ----NDGSTPRAFTKVSTFLSWIKK 243 + A GDSGGPL C+ GIVS+G N P FT+VS ++ WI + Sbjct: 189 GDGVISAC-NGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQ 247 Query: 244 TMK 246 ++ Sbjct: 248 KLQ 250 >3LC3-A nrPDB Length = 235 Score = 117 bits (293), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 81/240 (33%), Positives = 129/240 (53%), Gaps = 21/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQ-IMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGA 77 ++GG +AKP P+ L +D + CGG ++ E +++TAAHC +G KI V G Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAF-----CGGSIVNEKWIVTAAHCVETGVKITVVAGE 55 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKT--ISNDIMLLKLKSKAKRSSAVKPLNLPRR-- 133 HNI+E E +Q V++IIPH YN+ ++DI LL+L +S V P+ + + Sbjct: 56 HNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 134 -NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 N+ +K G YV+GWG++ G+ + LQ + + + + C K + N CAG Sbjct: 116 TNIFLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTK-FTIYNNMFCAGF 173 Query: 193 PKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + R S +GDSGGP V + GI+S+G+ + +TKVS +++WIK+ K Sbjct: 174 HEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >1LTO-A nrPDB Length = 245 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 127/248 (51%), Gaps = 26/248 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG EA P+ L++ D Y CGG LI +VLTAAHC G + L + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRY-WMHFCGGSLIHPQWVLTAAHCLGPDVK-DLATLRV 58 Query: 81 KEQEK----MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + +E+ Q++PV +II HP + DI LL+L+ SS V + LP + Sbjct: 59 QLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASET 118 Query: 137 VKPGDVCYVAGWGKLG---PMGKYSDTLQEVELTVQEDQKCES--YLKNY------FDKA 185 PG C+V GWG + P+ L++V++ + E+ C++ +L Y + Sbjct: 119 FPPGMPCWVTGWGDVDNDEPLPP-PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSY--GQNDGSTPRAFTKVSTFLS 239 + +CAG+ +R S +GDSGGPLVCK + AG+VS+ G + P +T+V+ +L Sbjct: 178 DMLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLD 235 Query: 240 WIKKTMKK 247 WI + K Sbjct: 236 WIHHYVPK 243 >1FON-A nrPDB Length = 240 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 115/241 (47%), Gaps = 18/241 (7%) Query: 24 GHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAHNIK 81 G +A P+S + LQ + + CGG LI D+V+TA HC + V LG ++ Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRS 61 Query: 82 EQEKMQQIIPVV--KIIPHPAYNSKTIS--NDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 E +Q+IP+ + HP +NS ++ NDI L+KL A+ V+ NLP + Sbjct: 62 VLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDIL 121 Query: 138 KPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKIK 196 CY++GWG+L G D LQ+ L + + C + K +CAG Sbjct: 122 PNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGD--T 179 Query: 197 RASFRGDSGGPLVC---------KKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 R+ GDSGGPL C V + + ++G N P FT+VS F+ WI +T+ Sbjct: 180 RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIAS 239 Query: 248 S 248 + Sbjct: 240 N 240 >4DUR-A nrPDB Length = 791 Score = 116 bits (291), Expect = 8e-27, Method: Composition-based stats. Identities = 88/248 (35%), Positives = 120/248 (48%), Gaps = 24/248 (9%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SG 68 PK G ++GG A PHS P+ L+ G CGG LI ++VLTAAHC Sbjct: 555 PKKCPGRVVGGCVAHPHSWPWQVSLRTR---FGMHFCGGTLISPEWVLTAAHCLEKSPRP 611 Query: 69 SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 S V LGAH E Q I V ++ P DI LLKL S A + V P Sbjct: 612 SSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPA 665 Query: 129 NLPRRNVKVKPGDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKAN 186 LP N V C++ GWG+ G G + L+E +L V E++ C Y N ++ Sbjct: 666 CLPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQST 723 Query: 187 EICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLSW 240 E+CAG S +GDSGGPLVC K + G+ S+G + P + +VS F++W Sbjct: 724 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 783 Query: 241 IKKTMKKS 248 I+ M+ + Sbjct: 784 IEGVMRNN 791 >3DFJ-A nrPDB Length = 263 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 118/247 (47%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-----INVTL 75 I GG A P+ Q+ Y G CGG L+ E +VL+AAHC S+ V L Sbjct: 1 ITGGSSAVAGQWPW----QVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH + + ++ + IIPHP+Y + DI LL+L S ++P++LP N Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANA 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKY--SDTLQEVELTVQEDQKCESYL-------KNYFDKAN 186 G C V GWG + P LQ++E+ + + C + + +F + + Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQED 176 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGS--TPRAFTKVSTFLSW 240 +CAG + + + +GDSGGPL C GIVS+G G+ P +T S++ SW Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 241 IKKTMKK 247 I+ + + Sbjct: 237 IQSKVTE 243 >1FXY-A nrPDB Length = 228 Score = 114 bits (285), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 77/232 (33%), Positives = 115/232 (49%), Gaps = 15/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG+ K P+ A L I +E G CGG ++ E ++LTAAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALL-INEENEGF--CGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 N +++E + + V +I H + +T DI +L+LK+ V P +LP Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLP--TAPPA 115 Query: 139 PGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 G C ++GWG G Y D LQ ++ V KCE+ +N C G + + Sbjct: 116 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFLEGGK 174 Query: 198 ASFRGDSGGPLVCKKVAAGIVSYGQNDGST----PRAFTKVSTFLSWIKKTM 245 S +GDSGGP+VC G+VS+G DG P +TKV ++ WIK T+ Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKVYNYVKWIKNTI 224 >1X7A-C nrPDB Length = 235 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 81/240 (33%), Positives = 128/240 (53%), Gaps = 21/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQ-IMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGA 77 I+GG AKP P+ L +D + CGG +I E +V+TAAHC G KI V G Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAF-----CGGSIINEKWVVTAAHCIEPGVKITVVAGE 55 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKT--ISNDIMLLKLKSKAKRSSAVKPLNLPRR-- 133 +N +E E +Q V++ IPH +YN+ S+DI LL+L +S V P+ + + Sbjct: 56 YNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 134 -NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 N+ +K G YV+GWG++ G+ + LQ +++ + + C K + +N CAG Sbjct: 116 TNIFLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTK-FTIYSNMFCAGF 173 Query: 193 PKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + + S +GDSGGP V + GI+S+G+ + +TKVS +++WIK+ K Sbjct: 174 HEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >3E0N-B nrPDB Length = 271 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 117/247 (47%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-----INVTL 75 I GG A P+ Q+ Y G CGG L+ E +VL+AAHC S+ V L Sbjct: 1 ITGGSSAVAGQWPW----QVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH + + ++ + IIPHP+Y + DI LL+L S ++P++LP Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQA 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKY--SDTLQEVELTVQEDQKCESYL-------KNYFDKAN 186 G C V GWG + P LQ++E+ + + C S + +F + + Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQED 176 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGS--TPRAFTKVSTFLSW 240 +CAG + + + +GDSGGPL C GIVS+G G+ P +T S++ SW Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 241 IKKTMKK 247 I+ + + Sbjct: 237 IQSKVTE 243 >4GSO-A nrPDB Length = 232 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 110/230 (47%), Gaps = 13/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG E + P++A+L YS CG LI +++V+TAAHC + + LG H+ Sbjct: 1 VLGGDECDINEHPFLAFL-----YSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSK 55 Query: 81 KE-QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K E Q P K I S+ + DIML+KL S + PL+LP V Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV-- 113 Query: 140 GDVCYVAGWGKLG-PMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWG + P Y D + + + + C+ N +CAG + + Sbjct: 114 GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAY-NGLPAKTTLCAGVLEGGKD 172 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTM 245 + GDSGGPL+C GIVSYG + G P +T V + WI++ + Sbjct: 173 TCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >2AIQ-A nrPDB Length = 231 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 71/230 (30%), Positives = 109/230 (47%), Gaps = 14/230 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 +IGG E + ++A + Y+ CGG LI +++VLTA HC + + LG HN+ Sbjct: 1 VIGGDECNINEHRFLALV-----YANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNL 55 Query: 81 KEQEK-MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K K + P K N DIML++L + S+ + PL+LP V Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV-- 113 Query: 140 GDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWG + P D + + + C++ K A +CAG + + Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGL--AATTLCAGILEGGKD 171 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 + +GDSGGPL+C GI+S G N + PR +TKV + WI+ + Sbjct: 172 TCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >5XW8-A nrPDB Length = 133 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 58/137 (42%), Positives = 76/137 (55%), Gaps = 7/137 (5%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + +I+GG+ +S PY L SGS CGG LI +V++AAHC S+I V Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSLN-----SGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V ++LPR Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 134 NVKVKPGDVCYVAGWGK 150 G C ++GWG Sbjct: 117 --CAAAGTECLISGWGN 131 >2F91-A nrPDB Length = 237 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 77/237 (32%), Positives = 110/237 (46%), Gaps = 19/237 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK--CGGFLIREDFVLTAAHC-------SGSKI 71 I+GG +A PY L + + G CG + E++ +TA HC + S + Sbjct: 1 IVGGTDATLGEFPYQ--LSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGL 58 Query: 72 NVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP 131 + G ++ E +QII V KII H ++ + NDI LLKL + V P+ LP Sbjct: 59 QIVAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALP 118 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG 191 + GDV V GWG G D LQ+V + + D+ C + + ICAG Sbjct: 119 EQG-HTATGDVI-VTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAG 176 Query: 192 DPKIKRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLSWIK 242 P+ + S +GDSGGPL AGIVS+G P +T+VS + WIK Sbjct: 177 VPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >4E7N-A nrPDB Length = 238 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 77/232 (33%), Positives = 112/232 (48%), Gaps = 11/232 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + ++ L S + CGG LI +++VLTAAHC + LG H+ Sbjct: 1 IIGGDECNINEHRFLVALYT--SRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSK 58 Query: 81 K-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K E Q +P K + N DIML++L S K S + P +LP V Sbjct: 59 KVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSV-- 116 Query: 140 GDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESYLKNYFDKANE--ICAGDPKIK 196 G VC + GWG++ P G Y D V + + E + C + + A +CAG + Sbjct: 117 GSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGG 176 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 + + +GDSGGPL+C GI S+G + + P A+TKV L WI+ + Sbjct: 177 KDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >1A5I-A nrPDB Length = 265 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 81/242 (33%), Positives = 122/242 (50%), Gaps = 29/242 (11%) Query: 31 SRPYMAYLQIMDEYSGSKK--CGGFLIREDFVLTAAHCSG-----SKINVTLG-AHNIKE 82 S P+ A + + S ++ CGG LI +VLTAAHC ++ V LG + +K Sbjct: 24 SHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKP 83 Query: 83 QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSK----AKRSSAVKPLNLPRRNVKVK 138 E+ +Q V K I H ++ T +NDI LL+LKS A+ S +V+ + LP N+++ Sbjct: 84 GEE-EQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQLP 142 Query: 139 PGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCE-SYLKNYFDKANEICAGD---- 192 C ++G+GK YS+ L+E + + +C +L N N +CAGD Sbjct: 143 DWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSG 202 Query: 193 ---PKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDG--STPRAFTKVSTFLSWIKK 243 P + A +GDSGGPLVC GI+S+G G P +TKV+ +L WI+ Sbjct: 203 EIYPNVHDAC-QGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNYLGWIRD 261 Query: 244 TM 245 M Sbjct: 262 NM 263 >1BDA-A nrPDB Length = 265 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 124/253 (49%), Gaps = 29/253 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK--CGGFLIREDFVLTAAHCSGSK-----INV 73 I GG A S P+ A + S ++ CGG LI ++L+AAHC + + V Sbjct: 14 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTV 73 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKR----SSAVKPLN 129 LG + +Q V K I H ++ T NDI LL+LKS + R SS V+ + Sbjct: 74 ILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVC 133 Query: 130 LPRRNVKVKPGDVCYVAGWGK---LGPMGKYSDTLQEVELTVQEDQKCES-YLKNYFDKA 185 LP ++++ C ++G+GK L P YS+ L+E + + +C S +L N Sbjct: 134 LPPADLQLPDWTECELSGYGKHEALSPF--YSERLKEAHVRLYPSSRCTSQHLLNRTVTD 191 Query: 186 NEICAGDPKIK------RASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTK 233 N +CAGD + + +GDSGGPLVC + GI+S+G G P +TK Sbjct: 192 NMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTK 251 Query: 234 VSTFLSWIKKTMK 246 V+ +L WI+ M+ Sbjct: 252 VTNYLDWIRDNMR 264 >1EQ9-A nrPDB Length = 222 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 113/233 (48%), Gaps = 17/233 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 I+GG +A PY L++ SGS +CG ++ + VLTAAHC +++ V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G + + E + V + + Y+ + ND+ L+ L + K + V+P+ L + Sbjct: 57 GTNYLSES---GDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDE 113 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 ++ + C + GWG G + LQE+EL V ++CE D IC K Sbjct: 114 DLE-SNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDS--HICTL-TKR 169 Query: 196 KRASFRGDSGGPLVCKKVAAGIVSYGQNDG-STPRAFTKVSTFLSWIKKTMKK 247 + GDSGGPLV GIVS+G P +T+VS+F+SWI +KK Sbjct: 170 GEGACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >3S9B-A nrPDB Length = 234 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 69/229 (30%), Positives = 108/229 (47%), Gaps = 9/229 (3%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG E + P++ L S + C G LI ++VLTAAHC I + LG H+ Sbjct: 1 VVGGDECNINEHPFLVAL--YTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSK 58 Query: 81 KEQEKMQQI-IPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + + +QI +P K + DIML++L+ S+ + P++LP R+ V Sbjct: 59 NIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV-- 116 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 G C + GWGK+ Y D + + + + CE + +CAG K R + Sbjct: 117 GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDT 175 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDGST---PRAFTKVSTFLSWIKKTM 245 GDSGGPL+C GIV+ G P +TKV + +WI+ + Sbjct: 176 CHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >2QY0-B nrPDB Length = 242 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 123/249 (49%), Gaps = 31/249 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC---------SGSKI 71 IIGG +AK + P+ + I + GG L+ + ++LTAAH S + + Sbjct: 1 IIGGQKAKMGNFPWQVFTNI------HGRGGGALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 72 NVTLGAHNIKEQEKMQQIIPVVKIIPHPAY---NSKTISNDIMLLKLKSKAKRSSAVKPL 128 +V LG N++E K+ P+ ++ HP Y S DI LL+L++ + P+ Sbjct: 55 DVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 113 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL--KNYFD--K 184 LP + G + YV+G+G + K + L+ V L V Q CE++L KN D Sbjct: 114 CLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFS 171 Query: 185 ANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFL 238 N CAG P +K+ + +GDSGG P + VA GIVS+G +TKV ++ Sbjct: 172 QNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYV 231 Query: 239 SWIKKTMKK 247 WIKK M++ Sbjct: 232 DWIKKEMEE 240 >1P57-B nrPDB Length = 255 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 113/250 (45%), Gaps = 31/250 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG------SKINVT 74 I+GG + P+ Q+ Y G+ CGG L+ D+VLTAAHC S+ V Sbjct: 1 IVGGRDTSLGRWPW----QVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAY------NSKTISNDIMLLKLKSKAKRSSAVKPL 128 GA +Q + V ++ H Y NS+ SNDI L+ L S + ++P+ Sbjct: 57 AGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPV 114 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES--YLKNYFDKAN 186 LP + G +C V GWG G+ + LQE + + + C + N K Sbjct: 115 CLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI-KPK 173 Query: 187 EICAGDPKIKRASFRGDSGGPLVCKKVAA--------GIVSYGQND--GSTPRAFTKVST 236 CAG P+ + +GDSGGP VC+ + GIVS+G P +TKVS Sbjct: 174 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSD 233 Query: 237 FLSWIKKTMK 246 F WI + +K Sbjct: 234 FREWIFQAIK 243 >1GPZ-A nrPDB Length = 399 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 127/259 (49%), Gaps = 31/259 (11%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 + P + +IIGG +AK + P+ + I + GG L+ + ++LTAAH Sbjct: 149 VNPVEQRQQIIGGQKAKMGNFPWQVFTNI------HGRGGGALLGDRWILTAAHTLYPKE 202 Query: 67 ----SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAY---NSKTISNDIMLLKLKSKA 119 S + ++V LG N++E K+ P+ ++ HP Y S DI LL+L++ Sbjct: 203 HEAQSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSV 261 Query: 120 KRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL- 178 + P+ LP + G + YV+G+G + K + L+ V L V Q CE++L Sbjct: 262 TLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLR 319 Query: 179 -KNYFD--KANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQNDGSTPR 229 KN D N CAG P +K+ + +GDSGG P + VA GIVS+G Sbjct: 320 GKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYG 379 Query: 230 AFTKVSTFLSWIKKTMKKS 248 +TKV ++ WIKK M++ Sbjct: 380 FYTKVLNYVDWIKKEMEEE 398 >1FIZ-A nrPDB Length = 263 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 118/246 (47%), Gaps = 27/246 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSK--KCGGFLIREDFVLTAAHCSGSKINVT---- 74 ++GG A+P + P+M LQI ++ + CGG L+ +VLTAAHC +K VT Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 75 -LGAHNI-----KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 GA+ + K + Q V +II H Y S NDI L+K+ + P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 129 NLPRRNVKVKPG---DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESY-LKNYFD 183 LP+ K P C+V GWG L G + S TLQE + + + + C S N Sbjct: 121 CLPQ--FKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRI 178 Query: 184 KANEICAGDPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQN--DGSTPRAFTKVS 235 ++ +CAG P+ K + +GDSGGPL+C+ V GI S+G P +T Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTW 238 Query: 236 TFLSWI 241 +L+WI Sbjct: 239 PYLNWI 244 >3T2N-A nrPDB Length = 372 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 113/251 (45%), Gaps = 31/251 (12%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG------SKINV 73 I+GG + P+ Q+ Y G+ CGG L+ D+VLTAAHC S+ V Sbjct: 117 RIVGGRDTSLGRWPW----QVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 172 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAY------NSKTISNDIMLLKLKSKAKRSSAVKP 127 GA +Q + V ++ H Y NS+ SNDI L+ L S + ++P Sbjct: 173 FAGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 230 Query: 128 LNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE--SYLKNYFDKA 185 + LP + G +C V GWG G+ + LQE + + + C + N K Sbjct: 231 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI-KP 289 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCKKVAA--------GIVSYGQND--GSTPRAFTKVS 235 CAG P+ + +GDSGGP VC+ + GIVS+G P +TKVS Sbjct: 290 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 349 Query: 236 TFLSWIKKTMK 246 F WI + +K Sbjct: 350 DFREWIFQAIK 360 >3S69-A nrPDB Length = 234 Score = 103 bits (257), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 76/231 (32%), Positives = 112/231 (48%), Gaps = 13/231 (5%) Query: 21 IIGGHEAKPHS-RPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHN 79 +IGG E + R +A+ S C G LI E++VLTAAHC + + LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFFN-----STGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHS 55 Query: 80 IKE-QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 K E Q P K I N + + DIML+KL S+ S + PL+LP V Sbjct: 56 KKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSV- 114 Query: 139 PGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 G VC++ GWG + P+ Y D + + +D C++ + +CAG + + Sbjct: 115 -GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGK 173 Query: 198 ASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTM 245 + GDSGGPL+C GIVS+G + G P +TKV + WI+ + Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >5TJX-A nrPDB Length = 263 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 69/240 (28%), Positives = 117/240 (48%), Gaps = 14/240 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK-CGGFLIREDFVLTAAHCSG-----SKINVT 74 I+GG E+ P+ LQ+ + + + CGG LI +VLTAAHC + Sbjct: 16 IVGGTESSWGEWPWQVSLQV--KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 G + + K + +II H Y ++DI L+KL++ + + KP++LP + Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKG 133 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 C+V GWG G+ + LQ+V + + +++C+ ++Y +CAG + Sbjct: 134 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 193 Query: 195 IKRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + + +GDSGGPLVCK GI S+G+ P +TKV+ ++ WI + + S Sbjct: 194 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 253 >1MD7-A nrPDB Length = 328 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 125/257 (48%), Gaps = 31/257 (12%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 + P + IIGG +AK + P+ + I + GG L+ + ++LTAAH Sbjct: 81 VNPVEQRQRIIGGQKAKMGNFPWQVFTNI------HGRGGGALLGDRWILTAAHTLYPKE 134 Query: 67 ----SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAY---NSKTISNDIMLLKLKSKA 119 S + ++V LG N++E K+ P+ ++ HP Y S DI LL+L++ Sbjct: 135 HEAQSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSV 193 Query: 120 KRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL- 178 + P+ LP + G + YV+G+G + K + L+ V L V Q CE++L Sbjct: 194 TLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLR 251 Query: 179 -KNYFD--KANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQNDGSTPR 229 KN D N CAG P +K+ + +GD+GG P + VA GIVS+G Sbjct: 252 GKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGYG 311 Query: 230 AFTKVSTFLSWIKKTMK 246 +TKV ++ WIKK M+ Sbjct: 312 FYTKVLNYVDWIKKEME 328 >5GVT-A nrPDB Length = 250 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/239 (29%), Positives = 112/239 (46%), Gaps = 12/239 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 I+GG A P+ LQ+ S + CGG +I +VLTAAHC + Sbjct: 1 IVGGTNASLGEWPWQVSLQV-KLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G ++ E K + ++I H Y + DI L+KL++ + KP++LP + Sbjct: 60 GILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 C+V GWG G+ + LQ+ + + +++C+ ++Y ICAG + Sbjct: 120 TNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 196 KRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + +GDSGGPLVCK GI S+G+ P +TKVS ++ WI + + S Sbjct: 180 GTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSS 238 >1C5M-D nrPDB Length = 255 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 118/240 (49%), Gaps = 21/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG E K P+ A L I +E G CGG ++ E ++LTAAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALL-INEENEGF--CGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN---- 134 N +++E + + V +I H + +T DI +L+LK+ V P LP R+ Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 117 Query: 135 --VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 + K G V+G+G+ G+ S L+ +E+ + C+ ++ N CAG Sbjct: 118 TLMTQKTG---IVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCK-LSSSFIITQNMFCAGY 173 Query: 193 PKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + + +GDSGGP V + GIVS+G+ + +TKV+ FL WI ++MK Sbjct: 174 DTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >1FIW-A nrPDB Length = 290 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 118/245 (48%), Gaps = 25/245 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK--CGGFLIREDFVLTAAHCSGSKINVT---- 74 IIGG +A + P+M LQI ++ + CGG L+ ++LTAAHC K VT Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 75 -LGAHNIKEQEKMQQIIP------VVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKP 127 GA + E + + P V KII H Y++ + +NDI L+K+ + P Sbjct: 61 IFGAKEV-EWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGP 119 Query: 128 LNLPR-RNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESY-LKNYFDK 184 LP+ R + C+VAGWG L + S LQE + + + C S N + Sbjct: 120 GCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIR 179 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQN--DGSTPRAFTKVST 236 + +CAG P+ K + +GDSGGPL+CK V GI S+G P +T + Sbjct: 180 STNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWS 239 Query: 237 FLSWI 241 +L+WI Sbjct: 240 YLNWI 244 >6I44-A nrPDB Length = 627 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 68/249 (27%), Positives = 117/249 (46%), Gaps = 12/249 (4%) Query: 11 SLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-- 68 S+ + I+GG ++ P+ LQ+ + CGG LI +VLTAAHC Sbjct: 370 SVCTTKTSTRIVGGTQSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGL 428 Query: 69 ---SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAV 125 + G + + K + +II H Y ++DI L+KL++ + + Sbjct: 429 PLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQ 488 Query: 126 KPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKA 185 KP+ LP + C+V GWG G+ + LQ+V + + +++C+ ++Y Sbjct: 489 KPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 548 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLS 239 +CAG + + + +GD+GGPLVCK GI S+G+ P +TKV+ ++ Sbjct: 549 RMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 608 Query: 240 WIKKTMKKS 248 WI + + S Sbjct: 609 WILEKTQSS 617 >5LPF-A nrPDB Length = 234 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 66/214 (30%), Positives = 104/214 (48%), Gaps = 17/214 (7%) Query: 47 SKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNS--- 103 S C G L+ + +VLTAAHC + +G ++ + +Q+ + + HP Y+ Sbjct: 26 SFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSG 84 Query: 104 -----KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMG-KY 157 +T +D+MLLKL V+ L LP R + PGD C VAGWG KY Sbjct: 85 PILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ--PGDQCQVAGWGTTAARRVKY 142 Query: 158 SDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGI 217 + L +T+ ++CE + N ICAG + + + DSGGPLVC + GI Sbjct: 143 NKGLTCSSITILSPKECEVFYPGVVTN-NMICAGLDR-GQDPCQSDSGGPLVCDETLQGI 200 Query: 218 VSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 248 +S+G P +T++ ++SWI K ++ + Sbjct: 201 LSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >4XDE-A nrPDB Length = 257 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 26/244 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 ++GG A + PY+A L Y G C G LI +VLTAAHC + + V L Sbjct: 3 VVGGLVALRGAHPYIAAL-----YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA-----VKPLNL 130 G + Q + V H A++ + +D+ LL+L+ A S A V+P++L Sbjct: 58 GQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSL 117 Query: 131 PRRNVKVKPGDVCYVAGWG-KLGPMGKYSDTLQEVELTVQEDQKCES-YLKNYFDKANEI 188 P + +C VAGWG + +Y+ LQE ++ ++C + + + Sbjct: 118 PSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGML 177 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAA-------GIVSYGQ--NDGSTPRAFTKVSTFLS 239 CAG + + +GDSGGPLVC+ AA GI+S+G D + P +T V+ +L+ Sbjct: 178 CAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLA 237 Query: 240 WIKK 243 WI++ Sbjct: 238 WIRE 241 >1KIG-H nrPDB Length = 241 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 73/238 (30%), Positives = 114/238 (47%), Gaps = 17/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG + P+ A L + +E G CGG ++ E +VLTAAHC + V +G Sbjct: 1 IVGGRDCAEGECPWQALL-VNEENEGF--CGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN---V 135 N +++E + V + H + +T DI +L+LK+ + V P LP ++ Sbjct: 58 NTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEA 117 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD-KANEICAGDPK 194 + V+G+G+ G+ S TL+ +E+ + C+ L + F N CAG Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCK--LSSSFTITPNMFCAGYDT 175 Query: 195 IKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + +GDSGGP V + GIVS+G+ + +TKVS FL WI K MK Sbjct: 176 QPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >1OP0-A nrPDB Length = 234 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 111/231 (48%), Gaps = 13/231 (5%) Query: 21 IIGGHEAKPHSRPYM-AYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHN 79 +IGG+E + ++ A+ + CGG LI ++V+TAAHC + + LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFF-----CGGTLINPEWVVTAAHCDSTDFQMQLGVHS 55 Query: 80 IKE-QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 K E Q P K I N++ + DIML+KL S + PL+LP V Sbjct: 56 KKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSV- 114 Query: 139 PGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 G VC + GWG + P+ + + D + + + C++ + +CAG + + Sbjct: 115 -GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGK 173 Query: 198 ASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTM 245 + GDSGGPL+C GIVSYG + G P +T V + WI++ + Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >2OLG-A nrPDB Length = 278 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 129/271 (47%), Gaps = 33/271 (12%) Query: 7 LLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSK-KCGGFLIREDFVLTAAH 65 LL + EA +I+ G + P P+ A + + + + CGG LI +++TAAH Sbjct: 9 LLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAH 68 Query: 66 CSGSKINVTLGAHN-IKEQEKMQQIIP------------------VVKIIPHPAY--NSK 104 C ++ +GA N ++ E P + + I HP Y SK Sbjct: 69 CVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSK 128 Query: 105 TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEV 164 +DI L++L + + ++ ++P+ LP+ N +V+ G V GWG+ G+YS Q++ Sbjct: 129 DRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKL 187 Query: 165 ELTVQEDQKCESYL--KNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVA-----AGI 217 + V ++C +++++CAG K K S GDSGGPL+ ++ G+ Sbjct: 188 AVPVVHAEQCAKTFGAAGVRVRSSQLCAGGEKAK-DSCGGDSGGPLLAERANQQFFLEGL 246 Query: 218 VSYGQNDGST--PRAFTKVSTFLSWIKKTMK 246 VS+G G+ P +TKV + WI+ ++ Sbjct: 247 VSFGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >2XXL-A nrPDB Length = 408 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 79/257 (30%), Positives = 113/257 (43%), Gaps = 35/257 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN----VTLG 76 + G+E K SRP+MA L+ CGG +I E ++LTAAHC N + LG Sbjct: 119 VSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRLG 178 Query: 77 AHNIKEQEKMQQ-------IIPVVKI-----IPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 H I +E +Q PVV + + H Y+++ I +DI LLKL Sbjct: 179 EHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQKH 238 Query: 125 VKPLNLPRRN---VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNY 181 +KP+ LP + K + +V GWG G SD L + + +Q C + Sbjct: 239 IKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSACSQAYRRA 297 Query: 182 FDKANEICAGDPKIKRASFRGDSGGPLVC----------KKVAAGIVSYGQ---NDGSTP 228 +++C G ++ S +GDSGGPL K V GIVS G S P Sbjct: 298 V-PLSQLCVGGGDLQD-SCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISLP 355 Query: 229 RAFTKVSTFLSWIKKTM 245 +T V ++ WI TM Sbjct: 356 GLYTNVGEYVQWITDTM 372 >3F6U-H nrPDB Length = 240 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 65/214 (30%), Positives = 100/214 (46%), Gaps = 18/214 (8%) Query: 50 CGGFLIREDFVLTAAHC--SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTIS 107 CG LI +VLTAAHC K+ V LG ++++ EK + + + ++ HP Y+ T Sbjct: 27 CGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTD 86 Query: 108 NDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK----PGDVCYVAGWGKLGPMGKYSD---- 159 NDI LL L A S + P+ LP + + G V GWG K + Sbjct: 87 NDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRT 146 Query: 160 -TLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCK----KVA 214 L +++ V +C + N + N +CAG ++ + GDSGGP+V Sbjct: 147 FVLNFIKIPVVPHNECSEVMSNMVSE-NMLCAGILGDRQDACEGDSGGPMVASFHGTWFL 205 Query: 215 AGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 G+VS+G+ G +TKVS +L WI ++ Sbjct: 206 VGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIR 239 >2OQ5-A nrPDB Length = 232 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 116/234 (49%), Gaps = 21/234 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG E + P+ A LQ + GS +CG LI ++++AAHC + ++ + Sbjct: 1 IVGGTEVEEGEWPWQASLQ----WDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASF 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G IK KM++ + +II H Y + DI L +L S ++AV + LP + Sbjct: 57 GV-TIKPS-KMKRGL--RRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY 112 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-ESYLKNYFDKANEICAGDPK 194 + +PGDV +V G+G L G + L++ ++T+ + C E N +CAG + Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLE 172 Query: 195 IKRASFRGDSGGPLVCKKVA-----AGIVSYGQNDG--STPRAFTKVSTFLSWI 241 K + +GDSGGPLV AGIVS+G + P +T+V+ WI Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 226 >1SC8-U nrPDB Length = 262 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 75/252 (29%), Positives = 120/252 (47%), Gaps = 28/252 (11%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSG---SKKCGGFLIREDFVLTAAHC-----SGSKI 71 +IIGG ++P+ A I + G + CGG LI +V++A HC Sbjct: 15 KIIGGEFTTIENQPWFA--AIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDY 72 Query: 72 NVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTIS--NDIMLLKLKSKAKR----SSAV 125 V LG + + + V +I H Y++ T++ NDI LLK++SK R S + Sbjct: 73 IVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTI 132 Query: 126 KPLNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDK 184 + ++LP + G C + G+GK Y + L+ + + ++C+ +Y+ Sbjct: 133 QTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQ--PHYYGS 190 Query: 185 ---ANEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVS 235 +CA DP+ K S +GDSGGPLVC + GIVS+G+ P +T+VS Sbjct: 191 EVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVS 250 Query: 236 TFLSWIKKTMKK 247 FL WI+ K+ Sbjct: 251 HFLPWIRSHTKE 262 >1BQY-A nrPDB Length = 234 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 93/201 (46%), Gaps = 7/201 (3%) Query: 50 CGGFLIREDFVLTAAHCSGSKINVTLGAHNIK-EQEKMQQIIPVVKIIPHPAYNSKTISN 108 CGG LI +D+V+TAAHC + + G H+ K E Q P K + Sbjct: 26 CGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILNEDEQTRDPKEKFFCPNRKKDDEVDK 85 Query: 109 DIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELT 167 DIML+KL S S + PL+LP V G VC + GWGK P + Y D + Sbjct: 86 DIMLIKLDSSVSNSEHIAPLSLPSSPPSV--GSVCRIMGWGKTIPTKEIYPDVPHCANIN 143 Query: 168 VQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN---D 224 + + C + +CAG + R + DSGGPL+C + GIVS+G + Sbjct: 144 ILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQ 203 Query: 225 GSTPRAFTKVSTFLSWIKKTM 245 P +TKV +L WIK + Sbjct: 204 PGEPGVYTKVFDYLDWIKSII 224 >3P8G-A nrPDB Length = 241 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 36/248 (14%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 ++GG +A P+ L + + CG LI +++++AAHC ++ Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQ---GHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 71 INVTLGAHNIKEQEKMQQIIPVV------KIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 LG H ++ Q+ P V +II HP +N T DI LL+L+ A+ SS Sbjct: 58 WTAFLGLH-----DQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSM 112 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDK 184 V+P+ LP + G +V GWG G + LQ+ E+ V + CE+ L Sbjct: 113 VRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQI-T 171 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVC-----KKVAAGIVSYGQNDGST----PRAFTKVS 235 +C G S +GDSGGPL + AG+VS+G DG P +T++ Sbjct: 172 PRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG--DGCAQRNKPGVYTRLP 229 Query: 236 TFLSWIKK 243 F WIK+ Sbjct: 230 LFRDWIKE 237 >2F83-A nrPDB Length = 625 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 66/232 (28%), Positives = 106/232 (45%), Gaps = 12/232 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG + P+ L + CGG +I ++LTAAHC S + V Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSP-TQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G N E ++ V +II H Y DI LLKL++ + + +P+ LP + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 + C+V GWG K +TLQ+ ++ + +++C+ + + ICAG + Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 566 Query: 196 KRASFRGDSGGPLVCKKVA----AGIVSYGQNDGSTPR--AFTKVSTFLSWI 241 + + +GDSGGPL CK GI S+G+ R +T V ++ WI Sbjct: 567 GKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >2XRC-A nrPDB Length = 565 Score = 92.4 bits (228), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 112/258 (43%), Gaps = 35/258 (13%) Query: 11 SLAPKTEAG----------EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFV 60 SL PK G I+GG A+ P+ Q+ + + CGG I ++ Sbjct: 302 SLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWI 357 Query: 61 LTAAHC-SGSKIN----VTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKL 115 LTAAHC SK + T I K I V +II H YN+ T NDI L+++ Sbjct: 358 LTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM 417 Query: 116 KSKAKRSSAVKPLNLPR----RNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQE 170 K + P ++P +P D C V+GWG+ + +S EV+L Sbjct: 418 KKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI--- 474 Query: 171 DQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKV-----AAGIVSYGQNDG 225 C + N F + CAG + +GDSGGPLVC G+VS+G+N G Sbjct: 475 -SNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG 533 Query: 226 --STPRAFTKVSTFLSWI 241 P +TKV+ + WI Sbjct: 534 KPEFPGVYTKVANYFDWI 551 >5O32-I nrPDB Length = 244 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 74/238 (31%), Positives = 107/238 (44%), Gaps = 25/238 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-SGSKIN----VTL 75 I+GG A+ P+ Q+ + + CGG I ++LTAAHC SK + T Sbjct: 1 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNL----P 131 I K I V +II H YN+ T NDI L+++K + P ++ P Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 116 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICA 190 +P D C V+GWG+ + +S EV+L C + N F + CA Sbjct: 117 WSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI----SNCSKFYGNRFYEKEMECA 172 Query: 191 GDPKIKRASFRGDSGGPLVCKKV-----AAGIVSYGQNDG--STPRAFTKVSTFLSWI 241 G + +GDSGGPLVC G+VS+G+N G P +TKV+ + WI Sbjct: 173 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 230 >6AOD-C nrPDB Length = 245 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 107/232 (46%), Gaps = 12/232 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG + P+ L + CGG +I ++LTAAHC S + V Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSP-TQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G E ++ V +II H Y DI LLKL++ + + + +P++LP + Sbjct: 60 GILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 + C+V GWG K +TLQ+ ++ + +++C+ + + ICAG + Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 196 KRASFRGDSGGPLVCKKVA----AGIVSYGQN--DGSTPRAFTKVSTFLSWI 241 + + +GD+GGPL CK GI S+G+ P +T V ++ WI Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >4Z6A-H nrPDB Length = 249 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 71/242 (29%), Positives = 112/242 (46%), Gaps = 23/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG P+ Q++ +G++ CGG LI +V++AAHC + + L Sbjct: 1 IVGGKVCPKGECPW----QVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G H++ E + +Q V ++I Y T ++DI LL+L + V PL LP R Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 136 KVKP---GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANE--ICA 190 + V+GWG+L G + L + + Q CE+ +Y K E CA Sbjct: 117 SERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEA---SYPGKITEYMFCA 173 Query: 191 GDPKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKT 244 G + S +GDSGGP GIVS+GQ + +T+VS ++ W++K Sbjct: 174 GYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKL 233 Query: 245 MK 246 M+ Sbjct: 234 MR 235 >2B9L-A nrPDB Length = 394 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 123/251 (49%), Gaps = 31/251 (12%) Query: 25 HEAKPHSRPYMAYLQIMDEYSGSKK----CGGFLIREDFVLTAAHCSGS------KINVT 74 +EA+ P+M + + GS + CGG LI VLT AHC S I + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 75 LGAHN-IKEQEKM-QQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 G + + E+E++ Q + ++I H +N KT+ ND+ LL L ++ + + LP+ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 133 RNVKVKPGDVCYVAGWGK--LGPMGKYSDTLQEVELTVQEDQKCESYLKN------YFDK 184 ++ ++ C+ +GWGK G +YS+ L++++L + KC++ L+N + Sbjct: 255 QS-QIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVC-------KKVAAGIVSY--GQNDGSTPRAFTKVS 235 +CAG + K + GD G PL C + + GIV++ G D + P + V+ Sbjct: 314 QTFVCAGGEQGKD-TCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVA 372 Query: 236 TFLSWIKKTMK 246 F +WI + M+ Sbjct: 373 HFRNWIDQEMQ 383 >2JET-B nrPDB Length = 128 Score = 90.9 bits (224), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 48/128 (37%), Positives = 70/128 (54%), Gaps = 4/128 (3%) Query: 24 GHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL-GAHNIKE 82 G +A P S P+ LQ + +G CGG LI ED+V+TAAHC +V + G + Sbjct: 1 GEDAIPGSWPWQVSLQ---DKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGS 57 Query: 83 QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDV 142 E+ Q++ + ++ +P +N T+ NDI LLKL + A+ S V + LP + PG V Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 143 CYVAGWGK 150 C GWGK Sbjct: 118 CATTGWGK 125 >1SI5-H nrPDB Length = 240 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 101/216 (46%), Gaps = 20/216 (9%) Query: 43 EYSGSKKCGGFLIREDFVLTAAHCSGSK----INVTLGAHNI--KEQEKMQQIIPVVKII 96 Y CGG LI+E +VLTA C S+ LG H++ + EK +Q++ V +++ Sbjct: 18 RYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLV 77 Query: 97 PHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGK 156 P +D++L+KL A V ++LP + C V GWG G + Sbjct: 78 YGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYTGLI-N 130 Query: 157 YSDTLQEVELTVQEDQKCESYLKNYFD-KANEICAGDPKIKRASFRGDSGGPLVCK---- 211 Y L+ L + ++KC + + +EICAG KI GD GGPLVC+ Sbjct: 131 YDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKM 190 Query: 212 KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 ++ G++ G+ + P F +V+ + WI K + Sbjct: 191 RMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >1ZJK-A nrPDB Length = 403 Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 77/257 (29%), Positives = 120/257 (46%), Gaps = 32/257 (12%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 L+ +T G+I GG +AKP P+ + G G L+ +++VLTAAH Sbjct: 153 LSARTTGGQIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQK 206 Query: 67 -SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSA 124 S +++ +G Q V I H Y NDI L+KL +K +S Sbjct: 207 HDASALDIRMGTLKRLSPHYTQAWSEAVFI--HEGYTHDAGFDNDIALIKLNNKVVINSN 264 Query: 125 VKPLNLPRRNVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNY 181 + P+ LPR+ + ++ D+ +GWG L G + L V++ + + QKC +Y K Sbjct: 265 ITPICLPRKEAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPP 323 Query: 182 FDK----ANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQ-NDGSTPR- 229 + + AN +CAG + S RGDSGG LV + GIVS+G N G + Sbjct: 324 YPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQY 383 Query: 230 -AFTKVSTFLSWIKKTM 245 +TKV ++ WI+ + Sbjct: 384 GVYTKVINYIPWIENII 400 >1Q3X-A nrPDB Length = 328 Score = 90.5 bits (223), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 77/257 (29%), Positives = 119/257 (46%), Gaps = 32/257 (12%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 L+ +T G I GG +AKP P+ + G G L+ +++VLTAAH Sbjct: 78 LSARTTGGRIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQK 131 Query: 67 -SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSA 124 S +++ +G Q V I H Y NDI L+KL +K +S Sbjct: 132 HDASALDIRMGTLKRLSPHYTQAWSEAVFI--HEGYTHDAGFDNDIALIKLNNKVVINSN 189 Query: 125 VKPLNLPRRNVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNY 181 + P+ LPR+ + ++ D+ +GWG L G + L V++ + + QKC +Y K Sbjct: 190 ITPICLPRKEAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPP 248 Query: 182 FDK----ANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQ-NDGSTPR- 229 + + AN +CAG + S RGDSGG LV + GIVS+G N G + Sbjct: 249 YPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQY 308 Query: 230 -AFTKVSTFLSWIKKTM 245 +TKV ++ WI+ + Sbjct: 309 GVYTKVINYIPWIENII 325 >5KWM-A nrPDB Length = 230 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 62/207 (29%), Positives = 95/207 (45%), Gaps = 15/207 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-GSK---INVTLG 76 I+GG +A P+ L D G + CGG L + V+TAAHC+ GS+ INV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPD---GQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR-RNV 135 + E + V + HP Y D+ +L L++ K + P+ L + + Sbjct: 58 RTVMSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEA----PIELAKADDA 111 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 P + GWG G+ +D LQ+ + V D C+ Y A +CAG P+ Sbjct: 112 GYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDA-MVCAGVPEG 170 Query: 196 KRASFRGDSGGPLVCKKVAAGIVSYGQ 222 + +GDSGGP+V G+ S+G+ Sbjct: 171 GVDTCQGDSGGPMVVNNKLIGVTSWGE 197 >5LHN-A nrPDB Length = 247 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 114/247 (46%), Gaps = 29/247 (11%) Query: 21 IIGGHEAKPHSRPYMA--YLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINV 73 I+GG + ++P+ A Y + S KCGG LI +V +AAHC V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTIS--NDIMLLKLKSK----AKRSSAVKP 127 LG + V ++I H Y +++ NDI LLK+++ A+ S +++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 128 LNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVEL------TVQEDQKCESYLKNY 181 + LP R G C + G+GK SD L L V +Q + + Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESE----SDYLYPKNLKMSVVKLVSHEQCMQPHYYGS 176 Query: 182 FDKANEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQN--DGSTPRAFTKVS 235 +CA DP+ K S +GDSGGPL+C + +GIVS+G+ + + P +T+VS Sbjct: 177 EINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVS 236 Query: 236 TFLSWIK 242 FL WI+ Sbjct: 237 HFLDWIQ 243 >3VGC-B nrPDB Length = 131 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 6/131 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH-- 78 I+ G EA P S P+ LQ + +G CGG LI E++V+TAAHC + +V + Sbjct: 1 IVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 EK+Q++ + K+ + YNS TI+NDI LLKL + A S V + LP + Sbjct: 58 QGSSSEKIQKL-KIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 116 Query: 139 PGDVCYVAGWG 149 G C GWG Sbjct: 117 AGTTCVTTGWG 127 >4IGD-A nrPDB Length = 406 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 66/253 (26%), Positives = 114/253 (45%), Gaps = 34/253 (13%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC------------ 66 +I G A+ + P++A L ++ G CGG L+ +++TAAHC Sbjct: 154 AQIFNGRPAQKGTTPWIAMLSHLN---GQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTL 210 Query: 67 ------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 S S + LG H ++ +Q + V HP Y+ T ND+ L++L Sbjct: 211 RDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPV 270 Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN 180 ++ V P+ LP + G + V+GWGK + ++ +TL E+E+ + + C+ Sbjct: 271 LNAFVMPICLPEG--PQQEGAMVIVSGWGKQF-LQRFPETLMEIEIPIVDHSTCQKAYAP 327 Query: 181 YFDKANE--ICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQNDGSTPR--A 230 K ICAG+ + + + GDSGGP+V + G VS+G + G R Sbjct: 328 LKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGV 387 Query: 231 FTKVSTFLSWIKK 243 ++ + WI++ Sbjct: 388 YSYIHHNKDWIQR 400 >4DJZ-B nrPDB Length = 251 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 66/252 (26%), Positives = 113/252 (44%), Gaps = 34/252 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-------------- 66 I G A+ + P++A L ++ G CGG L+ +++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLN---GQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 67 ----SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRS 122 S S + LG H ++ +Q + V HP Y+ T ND+ L++L + Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 117 Query: 123 SAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYF 182 + V P+ LP + G + V+GWGK + ++ +TL E+E+ + + C+ Sbjct: 118 AFVMPICLPEG--PQQEGAMVIVSGWGKQF-LQRFPETLMEIEIPIVDHSTCQKAYAPLK 174 Query: 183 DKANE--ICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQNDGSTPR--AFT 232 K ICAG+ + + + GDSGGP+V + G VS+G + G R ++ Sbjct: 175 KKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYS 234 Query: 233 KVSTFLSWIKKT 244 + WI++ Sbjct: 235 YIHHNKDWIQRV 246 >2ASU-B nrPDB Length = 234 Score = 86.7 bits (213), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 72/241 (29%), Positives = 109/241 (45%), Gaps = 30/241 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS------KINVT 74 ++GGH P + P+ L+ G CGG L++E ++LTA C S V Sbjct: 1 VVGGH---PGNSPWTVSLR---NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 75 LGA--HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 LG N + E Q +PV K++ P+ + ++LLKL+ + V + LP Sbjct: 55 LGTLFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPP 108 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVE-LTVQEDQKCESYLKNYFDKANEICAG 191 V PG C +AGWG+ G +DT+ V L V +Q+C + + +E+C Sbjct: 109 EWYVVPPGTKCEIAGWGET--KGTGNDTVLNVALLNVISNQECNIKHRGRV-RESEMCTE 165 Query: 192 DPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDGST--PRAFTKVSTFLSWIKKTM 245 + GD GGPL C V GI+ + + P FT+VS F+ WI K M Sbjct: 166 GLLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 225 Query: 246 K 246 + Sbjct: 226 R 226 >2PKA-B nrPDB Length = 152 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 53/155 (34%), Positives = 85/155 (54%), Gaps = 13/155 (8%) Query: 102 NSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMG---KYS 158 + K S+D+MLL+L+S AK + AVK L LP + ++ G C +GWG + P ++ Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 159 DTLQEVELTVQEDQKCESYLKNYFDKANE--ICAGDPKIKRASFRGDSGGPLVCKKVAAG 216 D +Q V+LT+ ++ C + DK E +CAG + + GDSGGPL+C + G Sbjct: 60 DEIQCVQLTLLQNTFCA---DAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQG 116 Query: 217 IVSYGQN---DGSTPRAFTKVSTFLSWIKKTMKKS 248 I S+G + P +TK+ +L WI T+ ++ Sbjct: 117 ITSWGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >2HLC-A nrPDB Length = 230 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 112/232 (48%), Gaps = 17/232 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G+EA PY A L I + CGG LI ++LTAAHC ++V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR-RNVKVKP 139 + E + ++ +II H +N T ND+ L+K+ + + ++P+ LP + K Sbjct: 61 VQYEG-EAVVNSERIISHSMFNPDTYLNDVALIKIP-HVEYTDNIQPIRLPSGEELNNKF 118 Query: 140 GDV-CYVAGWGKLGPMGKYSDT--LQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 ++ V+GWG+ +DT LQ V ++ +C + IC GD Sbjct: 119 ENIWATVSGWGQ-----SNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDG 172 Query: 197 RASFRGDSGGPLVC--KKVAAGIVSYGQNDGST---PRAFTKVSTFLSWIKK 243 ++ GDSGGP V K + G+VS+ G P F++V++++ WI++ Sbjct: 173 KSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >4IW4-E nrPDB Length = 279 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 75/267 (28%), Positives = 116/267 (43%), Gaps = 43/267 (16%) Query: 21 IIGGHEAKPHSRPYMAYLQIMD--EYSGSKKCG-GFLIREDFVLTAAHC----------- 66 IIGG A+P P+ A + + D K G G L+ ++LTAAH Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 67 --SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 S + V LG H+++++ +++ HP +N + ++DI L++L+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNS-SAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 125 VKPLNLPRRNVK-VKPGDVCYVAGWGKLGP-----------MGKYSDTLQEVELTVQEDQ 172 V P+ LPR + P + VAGWG P SD LQ V+L V Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 173 KC----ESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQ 222 +C ES NY N CAG + + + GDSGG V + V G+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 223 NDGSTPR----AFTKVSTFLSWIKKTM 245 + + +TKVS ++ W+ + M Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >4FXG-H nrPDB Length = 242 Score = 83.6 bits (205), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 114/248 (45%), Gaps = 32/248 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC------SGSKINVT 74 I GG +AKP P+ + G G L+ +++VLTAAH S +++ Sbjct: 1 IYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 54 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 +G Q V I H Y NDI L+KL +K +S + P+ LPR+ Sbjct: 55 MGTLKRLSPHYTQAWSEAVFI--HEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRK 112 Query: 134 NVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNYFDK----AN 186 + ++ D+ +GWG L G + L V++ + + QKC +Y K + + AN Sbjct: 113 EAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTAN 171 Query: 187 EICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQ-NDGSTPR--AFTKVSTF 237 +CAG + S RGD+GG LV + GIVS+G N G + +TKV + Sbjct: 172 MLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINY 231 Query: 238 LSWIKKTM 245 + WI+ + Sbjct: 232 IPWIENII 239 >1YM0-A nrPDB Length = 238 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 111/242 (45%), Gaps = 18/242 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKINVTLG 76 I+GG EA+P+ P+ + + + S S CGG +I + +V+ AAHC + + +++ +G Sbjct: 1 IVGGIEARPYEFPWQ--VSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR-RNV 135 H+ ++Q V I + Y+ T+ ND+ ++K V P+ P N Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 136 KVKPGDVCYVAGWGKLGPMGKYS-DTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 V C +GWG + G L+ V L + + C++ + + ICA D Sbjct: 119 YVYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNT 176 Query: 195 --IKRASFRGDSGGPLVCKKVAA-----GIVSYGQNDGST-PRAFTKVSTFLSWIKKTMK 246 R S +GDSGGPL K + GIVS+G S P +++V WI T+ Sbjct: 177 GMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTIT 236 Query: 247 KS 248 + Sbjct: 237 NN 238 >3BEU-A nrPDB Length = 224 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 101/240 (42%), Gaps = 32/240 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC---SGSKINVTLGA 77 ++GG A P+M L S CGG L +D VLTAAHC SG+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P + +T D L+KL +P+N P + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKL---------AQPINQPTLKIAT 103 Query: 138 KPG---DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANE-ICAGDP 193 VAGWG G L + + D C S ++ ANE ICAG Sbjct: 104 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSS-SSFILVANEMICAGYD 162 Query: 194 KIKRASFRGDSGGPLVCKK-----VAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + + +GDSGGP+ K V GIVS+G+ + +T+VSTF S I + Sbjct: 163 TKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 222 >3I77-A nrPDB Length = 230 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/241 (30%), Positives = 103/241 (42%), Gaps = 28/241 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC---SGSKINVTLGA 77 ++GG A P+M L I +E G CGG L +D VLTAAHC SG+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL-INEENEG--FCGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P + +T D L+KL +P+N P + Sbjct: 58 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKL---------AQPINQPTLKIAT 108 Query: 138 KPG---DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANE-ICAGDP 193 VAGWG G L + + D C S ++ ANE ICAG P Sbjct: 109 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSS-SSFILVANEMICAGYP 167 Query: 194 KIKRA-SFRGDSGGPLVCKK-----VAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 + +GDSGGP+ K + GIVS+G P +T+VSTF S I Sbjct: 168 DTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAA 227 Query: 246 K 246 + Sbjct: 228 R 228 >2FMJ-A nrPDB Length = 222 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 69/239 (28%), Positives = 96/239 (40%), Gaps = 32/239 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC---SGSKINVTLGA 77 ++GG A P+M L S CGG L +D VLTAAHC SG+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P YN D L+KL +P+N P + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGYNG--TGKDWALIKL---------AQPINQPTLKIAT 101 Query: 138 KPG---DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 VAGWG G L + + D C S N EICAG Sbjct: 102 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDT 161 Query: 195 IKRASFRGDSGGPLVCKK-----VAAGIVSYGQNDGSTPR--AFTKVSTFLSWIKKTMK 246 + +GDSGGP+ K + GIVS+G+ + +T+VSTF S I + Sbjct: 162 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 220 >4KKD-A nrPDB Length = 433 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 74/267 (27%), Positives = 115/267 (43%), Gaps = 43/267 (16%) Query: 21 IIGGHEAKPHSRPYMAYLQIMD--EYSGSKKCG-GFLIREDFVLTAAHC----------- 66 IIGG A+P P+ A + + D K G G L+ ++LTAAH Sbjct: 155 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 214 Query: 67 --SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 S + V LG H+++++ +++ HP +N + ++DI L++L+ Sbjct: 215 PVSKEHVTVYLGLHDVRDKSGAVNS-SAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 125 VKPLNLPRRNVK-VKPGDVCYVAGWGKLGP-----------MGKYSDTLQEVELTVQEDQ 172 V P+ LPR + P + VAGWG P SD LQ V+L V Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 173 KC----ESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQ 222 +C ES NY N CAG + + + GDSG V + V G+VS+G Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWGG 393 Query: 223 NDGSTPR----AFTKVSTFLSWIKKTM 245 + + +TKVS ++ W+ + M Sbjct: 394 PEECGSKQVYGVYTKVSNYVDWVWEQM 420 >4LK4-A nrPDB Length = 357 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 68/244 (27%), Positives = 117/244 (47%), Gaps = 26/244 (10%) Query: 18 AGEIIGGHEAKPHSRPYMAYL--QIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKI 71 + II G A P + L + D Y G + CGG + +VLTAAHC S + + Sbjct: 8 SSRIINGSNANSAEWPSIVALVKRGADAYQG-QFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 72 NVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNL- 130 +V +GA+++ + ++ I KI H +Y+ + NDI +++L ++S++ + L Sbjct: 67 DVIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLNDIAIVEL----AQTSSLPAITLA 121 Query: 131 -PRRNVKVKPGDVCYVAGWGKL--GPMGKYSDTLQEVELTVQEDQKCESYLKNYFD---K 184 P + VAGWG +++ LQEV++ + C+ +++ Sbjct: 122 GPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPN 181 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCK--KVAAGIVSYGQNDGS---TPRAFTKVSTFLS 239 + CA ++ + S +GD+GGP+V K + GIVS+G + T +T VS F Sbjct: 182 STNFCAA--RLTKDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRD 239 Query: 240 WIKK 243 WI K Sbjct: 240 WITK 243 >5XRF-A nrPDB Length = 242 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/233 (28%), Positives = 107/233 (45%), Gaps = 15/233 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 +IGG+E + ++A + +C G LI E++VL AAHC +N+ LG HN Sbjct: 7 VIGGNECDTNEHRFLA--AFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQ 64 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 Q +Q ++ + T D++LLKL S+ + PL+LP + Sbjct: 65 SIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSI-- 122 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEV----ELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 G VC V GWG M D L +V + + +C ++ + + +CAG + Sbjct: 123 GSVCRVMGWGI---MSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEG 179 Query: 196 KRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 + DSGGPL+C GIV +G+ + P +T+VS + WI+ + Sbjct: 180 GIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >3H7O-A nrPDB Length = 228 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/207 (29%), Positives = 93/207 (44%), Gaps = 10/207 (4%) Query: 47 SKKCGGFLIREDFVLTAAHCSGSK----INVTLGAHNIKEQEKMQQIIPVVKIIPHPAYN 102 S CGG ++ + FVLTAAHC + I + + N+ E P V + Y Sbjct: 25 SLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTNLWEDPGKSD--PYVSHVYLSFYR 82 Query: 103 SKTISNDIMLLKLKSKAKRSS-AVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTL 161 +T+ NDI +L+L K KP LP + K G V+G+G M L Sbjct: 83 QETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKTGSDVLVSGYGDGQTMDPKDHDL 142 Query: 162 QEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSY- 220 + +LTV + +C + F CA K+ + GD+G P V + G+ +Y Sbjct: 143 KSAQLTVVDLDECRTKYGPIFLSLQVFCAQ--KVGVSLESGDAGDPTVQQDTLVGVAAYF 200 Query: 221 GQNDGSTPRAFTKVSTFLSWIKKTMKK 247 + P FTKV +++SWI+ +KK Sbjct: 201 PKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >1ELV-A nrPDB Length = 333 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/263 (28%), Positives = 115/263 (43%), Gaps = 39/263 (14%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P E IIGG +A + P+ + + GG LI E +VLTAAH Sbjct: 76 PFEEKQRIIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREP 128 Query: 74 TL--GAHNIKEQE--KMQQIIPVVKIIPHPAY-------NSKTISNDIMLLKLKSKAKRS 122 T+ G+ +++ K + + P I HP + NDI L++LK K Sbjct: 129 TMYVGSTSVQTSRLAKSKMLTPEHVFI-HPGWKLLAVPEGRTNFDNDIALVRLKDPVKMG 187 Query: 123 SAVKPLNLP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY--- 177 V P+ LP + + GD+ ++GWG+ + + L+ L V +KC+ Sbjct: 188 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVE 246 Query: 178 -----LKNYFDKANEICAGDPKIKRASFRGDSGGPLVC-------KKVAAGIVSYGQNDG 225 + Y N ICAG K S +GDSGG K AAG+VS+G G Sbjct: 247 KPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 305 Query: 226 STPRAFTKVSTFLSWIKKTMKKS 248 T +T+V ++ WI KTM+++ Sbjct: 306 -TYGLYTRVKNYVDWIMKTMQEN 327 >1M9U-A nrPDB Length = 241 Score = 77.4 bits (189), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 68/241 (28%), Positives = 96/241 (39%), Gaps = 24/241 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG----SKINVTLG 76 +IGG A P P+ Q S S CG L+ L+A+HC + I V G Sbjct: 1 VIGGTNASPGEFPWQLSQQ-RQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTIS--NDIMLLKLKSKAKRSSAVKPLNLPRRN 134 + Q V H Y + T S NDI +L L + ++ LP N Sbjct: 60 LWQ-QSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL-----KNYFDKANEIC 189 G C ++GWG+ D LQ+ + V +C + + N +D N IC Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWD--NHIC 176 Query: 190 AGDPKIKRASFRGDSGGPLVCKKVAA---GIVSYGQNDG------STPRAFTKVSTFLSW 240 DP + GDSGGPL C G+ S+ + G P +T+VS +L W Sbjct: 177 VQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGW 236 Query: 241 I 241 I Sbjct: 237 I 237 >5UBM-A nrPDB Length = 252 Score = 77.0 bits (188), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 113/256 (44%), Gaps = 39/256 (15%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL--GAH 78 IIGG +A + P+ + + GG LI E +VLTAAH T+ G+ Sbjct: 2 IIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREPTMYVGST 54 Query: 79 NIKEQE--KMQQIIPVVKIIPHPAY-------NSKTISNDIMLLKLKSKAKRSSAVKPLN 129 +++ K + + P I HP + NDI L++LK K V P+ Sbjct: 55 SVQTSRLAKSKMLTPEHVFI-HPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 130 LP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY--------LK 179 LP + + GD+ ++GWG+ + + L+ L V +KC+ + Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAE 172 Query: 180 NYFDKANEICAGDPKIKRASFRGDSGGPLVC-------KKVAAGIVSYGQNDGSTPRAFT 232 Y N ICAG K S +GDSGG K AAG+VS+G G T +T Sbjct: 173 AYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG-TYGLYT 230 Query: 233 KVSTFLSWIKKTMKKS 248 +V ++ WI KTM+++ Sbjct: 231 RVKNYVDWIMKTMQEN 246 >4J1Y-A nrPDB Length = 397 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 75/263 (28%), Positives = 114/263 (43%), Gaps = 39/263 (14%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P E IGG +A + P+ + + GG LI E +VLTAAH Sbjct: 140 PFEEKARAIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREP 192 Query: 74 TL--GAHNIKEQE--KMQQIIPVVKIIPHPAY-------NSKTISNDIMLLKLKSKAKRS 122 T+ G+ +++ K + + P I HP + NDI L++LK K Sbjct: 193 TMYVGSTSVQTSRLAKSKMLTPEHVFI-HPGWKLLEVPEGRTNFDNDIALVRLKDPVKMG 251 Query: 123 SAVKPLNLP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY--- 177 V P+ LP + + GD+ ++GWG+ + + L+ L V +KC+ Sbjct: 252 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVE 310 Query: 178 -----LKNYFDKANEICAGDPKIKRASFRGDSGGPLVC-------KKVAAGIVSYGQNDG 225 + Y N ICAG K S +GDSGG K AAG+VS+G G Sbjct: 311 KPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 369 Query: 226 STPRAFTKVSTFLSWIKKTMKKS 248 T +T+V ++ WI KTM+++ Sbjct: 370 -TYGLYTRVKNYVDWIMKTMQEN 391 >3NXP-A nrPDB Length = 424 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 45/278 (16%) Query: 11 SLAPKTEA--------GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLT 62 SL KTE G I+ G +A+ P+ L + CG LI + +VLT Sbjct: 148 SLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLT 205 Query: 63 AAHC----------SGSKINVTLGAHNIKEQEK-MQQIIPVVKIIPHPAYNSK-TISNDI 110 AAHC + + + V +G H+ E+ +++I + KI HP YN + + DI Sbjct: 206 AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI 265 Query: 111 MLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKL-----GPMGK-YSDTL 161 L+KLK S + P+ LP R ++ G V GWG L +GK L Sbjct: 266 ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL 325 Query: 162 QEVELTVQEDQKCESYLKNYFDKANEICAG---DPKIKRASFRGDSGGPLVCKK------ 212 Q V L + E C+ + N CAG D + + GDSGGP V K Sbjct: 326 QVVNLPIVERPVCKDSTRIRITD-NMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRW 384 Query: 213 VAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ DG +T V WI+K + + Sbjct: 385 YQMGIVSWGEGCDRDGKYG-FYTHVFRLKKWIQKVIDQ 421 >3K65-B nrPDB Length = 308 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 82/278 (29%), Positives = 119/278 (42%), Gaps = 45/278 (16%) Query: 11 SLAPKTEA--------GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLT 62 SL KTE G I+ G +A+ P+ L + CG LI + +VLT Sbjct: 32 SLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLT 89 Query: 63 AAHC----------SGSKINVTLGAHNIKEQEK-MQQIIPVVKIIPHPAYNSK-TISNDI 110 AAHC + + + V +G H+ E+ +++I + KI HP YN + + DI Sbjct: 90 AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI 149 Query: 111 MLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKL-----GPMGK-YSDTL 161 L+KLK S + P+ LP R ++ G V GWG L +GK L Sbjct: 150 ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL 209 Query: 162 QEVELTVQEDQKCESYLKNYFDKANEICAG---DPKIKRASFRGDSGGPLVCKK------ 212 Q V L + E C+ + N CAG D + + GD+GGP V K Sbjct: 210 QVVNLPIVERPVCKDSTRIRITD-NMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRW 268 Query: 213 VAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ DG +T V WI+K + + Sbjct: 269 YQMGIVSWGEGCDRDGKYG-FYTHVFRLKKWIQKVIDQ 305 >4NZQ-A nrPDB Length = 557 Score = 74.7 bits (182), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 78/262 (29%), Positives = 114/262 (43%), Gaps = 37/262 (14%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SG 68 G I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 297 GRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 69 SKINVTLGAHNIKEQEK-MQQIIPVVKIIPHPAYNSK-TISNDIMLLKLKSKAKRSSAVK 126 + + V +G H+ E+ +++I + KI HP YN + + DI L+KLK S + Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 414 Query: 127 PLNLPRRNVK---VKPGDVCYVAGWGKL-----GPMGK-YSDTLQEVELTVQEDQKCESY 177 P+ LP R ++ G V GWG L +GK LQ V L + E C+ Sbjct: 415 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 474 Query: 178 LKNYFDKANEICAG---DPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQ---NDG 225 + N CAG D + + GDSGGP V K GIVS+G+ DG Sbjct: 475 TRIRITD-NMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 533 Query: 226 STPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 534 KYG-FYTHVFRLKKWIQKVIDQ 554 >1MKW-K nrPDB Length = 308 Score = 73.2 bits (178), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 113/262 (43%), Gaps = 37/262 (14%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SG 68 G I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 48 GRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 69 SKINVTLGAHN-IKEQEKMQQIIPVVKIIPHPAYNSK-TISNDIMLLKLKSKAKRSSAVK 126 + V +G H+ + + K+++I + KI HP YN K + DI LLKLK + S + Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIH 165 Query: 127 PLNLPRRNVKVK---PGDVCYVAGWGKLGPMGKYS------DTLQEVELTVQEDQKCESY 177 P+ LP + K G V GWG S LQ V L + E C++ Sbjct: 166 PVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAS 225 Query: 178 LKNYFDKANEICAG--DPKIKRA-SFRGDSGGPLVCKK------VAAGIVSYGQ---NDG 225 + N CAG + KR + GDSGGP V K GIVS+G+ DG Sbjct: 226 TRIRITD-NMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDG 284 Query: 226 STPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 285 KYG-FYTHVFRLKKWIQKVIDR 305 >1VR1-H nrPDB Length = 261 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 77/262 (29%), Positives = 114/262 (43%), Gaps = 37/262 (14%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKK--CGGFLIREDFVLTAAHC----------SG 68 I+ G +A+ P+ L S ++ CG LI + +VLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 SKINVTLGAHNIKEQEK-MQQIIPVVKIIPHPAYNSK-TISNDIMLLKLKSKAKRSSAVK 126 + + V +G H+ E+ +++I + KI HP YN + + DI L+KLK S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 127 PLNLPRRNVK---VKPGDVCYVAGWGKL-----GPMGK-YSDTLQEVELTVQEDQKCESY 177 P+ LP R ++ G V GWG L +GK LQ V L + E C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 178 LKNYFDKANEICA---GDPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQ---NDG 225 + N CA D + + GDSGGP V K GIVS+G+ DG Sbjct: 181 TRIRITD-NMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 239 Query: 226 STPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 240 KYG-FYTHVFRLKKWIQKVIDQ 260 >1EPT-B nrPDB Length = 82 Score = 72.4 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 37/81 (45%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 69 SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 S+I V LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 129 NLPRRNVKVKPGDVCYVAGWG 149 +LPR G C ++GWG Sbjct: 61 SLPRSCAAA--GTECLISGWG 79 >1ETT-H nrPDB Length = 259 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 73/231 (31%), Positives = 102/231 (44%), Gaps = 35/231 (15%) Query: 50 CGGFLIREDFVLTAAHC----------SGSKINVTLGAHN-IKEQEKMQQIIPVVKIIPH 98 CG LI + +VLTAAHC + + V +G H+ + + K+++I + KI H Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIH 87 Query: 99 PAYNSK-TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK---PGDVCYVAGWGKLGPM 154 P YN K + DI LLKLK + S + P+ LP + K G V GWG Sbjct: 88 PRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 Query: 155 GKYS------DTLQEVELTVQEDQKCESYLKNYFDKANEICAG--DPKIKRA-SFRGDSG 205 S LQ V L + E C++ + N CAG + KR + GDSG Sbjct: 148 WTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITD-NMFCAGYKPGEGKRGDACEGDSG 206 Query: 206 GPLVCKK------VAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKK 247 GP V K GIVS+G+ DG +T V WI+K + + Sbjct: 207 GPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG-FYTHVFRLKKWIQKVIDR 256 >2OCV-B nrPDB Length = 259 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 102/231 (44%), Gaps = 35/231 (15%) Query: 50 CGGFLIREDFVLTAAHC----------SGSKINVTLGAHNIKEQEK-MQQIIPVVKIIPH 98 CG LI + +VLTAAHC + + + V +G H+ E+ +++I + KI H Sbjct: 28 CGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVH 87 Query: 99 PAYNSK-TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKLGPM 154 P YN + + DI LLKLK S + P+ LP + ++ G V GWG L Sbjct: 88 PRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRET 147 Query: 155 GKYS------DTLQEVELTVQEDQKCESYLKNYFDKANEICAG----DPKIKRASFRGDS 204 + LQ V L + E C++ + N CAG D K A GDS Sbjct: 148 WTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITD-NMFCAGFKVNDTKRGDAC-EGDS 205 Query: 205 GGPLVCKK------VAAGIVSYGQNDGSTPRA--FTKVSTFLSWIKKTMKK 247 GGP V K GIVS+G+ + +T V +WI+K + + Sbjct: 206 GGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKAWIQKVIDQ 256 >6BQM-A nrPDB Length = 506 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 74/261 (28%), Positives = 117/261 (44%), Gaps = 52/261 (19%) Query: 16 TEAG---EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG---- 68 TE+G IIGG +A PYM L + S CGG + +VLTAAHC Sbjct: 3 TESGVSSRIIGGEQATAGEWPYMVALTARN--SSHVFCGGSYLGGRYVLTAAHCVDKEDP 60 Query: 69 SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 +K +V LGA ++ + ++ I V +I H +Y + ++ NDI +L+L+ Sbjct: 61 AKGDVLLGAFDMNDVNTAER-IHVRQIYVHNSYITASMGNDIAVLELERDP--------- 110 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPM------------GKYSD---TLQEVELTVQEDQK 173 LPRR+V++ D K PM G+ SD L +V++ + Sbjct: 111 -LPRRSVQIS--DSSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPE 167 Query: 174 C-----ESYLKNYFDK--ANEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQ 222 C + KN + + N CAG + + GD+GGP+ + G+VS+G Sbjct: 168 CKTKGSDQDAKNNYSQLTNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGD 225 Query: 223 NDG--STPRAFTKVSTFLSWI 241 G ++P +T +S F W+ Sbjct: 226 GCGRANSPGVYTNLSVFNDWL 246 >4BXW-A nrPDB Length = 423 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 114/247 (46%), Gaps = 25/247 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+ G + K P+ A L +DE G CGG ++ +VLTAAHC I+V +G Sbjct: 170 IVNGMDCKLGECPWQAAL--VDEKEGVF-CGGTILSPIYVLTAAHCINETETISVVVGEI 226 Query: 79 NIKEQEKMQQIIPVVKII-------PHPAY--NSKTISNDIMLLKLKSKAKRSSAVKPLN 129 + K + + ++ V KI P AY + DI ++++K+ + S V P Sbjct: 227 D-KSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPAC 285 Query: 130 LPR---RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKAN 186 LP N + D V+G+G++ G S TL+ +++ + C + N Sbjct: 286 LPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPI-TPN 344 Query: 187 EICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDGSTPR--AFTKVSTFLSW 240 CAG + R + +GDSGGP GIVS G+ + +TK+S F+ W Sbjct: 345 MFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPW 404 Query: 241 IKKTMKK 247 IK+ M++ Sbjct: 405 IKRIMRQ 411 >5TO3-B nrPDB Length = 409 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 101/231 (43%), Gaps = 35/231 (15%) Query: 50 CGGFLIREDFVLTAAHC----------SGSKINVTLGAHNIKEQEK-MQQIIPVVKIIPH 98 CG LI + +VLTAAHC + + + V +G H+ E+ +++I + KI H Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIH 87 Query: 99 PAYNSK-TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKL--- 151 P YN + + DI L+KLK S + P+ LP R ++ G V GWG L Sbjct: 88 PRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET 147 Query: 152 --GPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG---DPKIKRASFRGDSG 205 +GK LQ V L + E C+ + N CAG D + + GDSG Sbjct: 148 WTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITD-NMFCAGYKPDEGKRGDACEGDSG 206 Query: 206 GPLVCKK------VAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKK 247 GP V K GIVS G DG +T V WI+K + + Sbjct: 207 GPFVMKSPFNNRWYQMGIVSAGAGCDRDGKY-GFYTHVFRLKKWIQKVIDQ 256 >2KAI-A nrPDB Length = 80 Score = 66.2 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + +S P+ Q+ + S +CGG L+ +VLTAAHC V LG HN+ Sbjct: 1 IIGGRECEKNSHPW----QVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYN 102 E E Q V PHP +N Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >4X0L-C nrPDB Length = 259 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 115/270 (42%), Gaps = 53/270 (19%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA--------- 64 P I+GGH S P+ A + + G LI E ++LT A Sbjct: 8 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLT----TGATLINEQWLLTTAKNLFLNHSE 63 Query: 65 HCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + + I TL + K +Q++ + K++ HP Y+ DI L+KLK K + Sbjct: 64 NATAKDIAPTLTLYVGK-----KQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNER 114 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNY--- 181 V P+ LP ++ + G V YV+GWG+ K++D L+ V L V + +C +++Y Sbjct: 115 VMPICLPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQC---IRHYEGS 169 Query: 182 ----------------FDKANEICAGDPKIKRASFRGDSGGPLVCKKV------AAGIVS 219 + CAG K + + GD+G + A GI+S Sbjct: 170 TVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILS 229 Query: 220 YGQNDGSTPR-AFTKVSTFLSWIKKTMKKS 248 + ++ + KV++ W++KT+ ++ Sbjct: 230 FDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 115/270 (42%), Gaps = 53/270 (19%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA--------- 64 P I+GGH S P+ A + + G LI E ++LT A Sbjct: 64 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLT----TGATLINEQWLLTTAKNLFLNHSE 119 Query: 65 HCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + + I TL + K +Q++ + K++ HP Y+ DI L+KLK K + Sbjct: 120 NATAKDIAPTLTLYVGK-----KQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNER 170 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNY--- 181 V P+ LP ++ + G V YV+GWG+ K++D L+ V L V + +C +++Y Sbjct: 171 VMPICLPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQC---IRHYEGS 225 Query: 182 ----------------FDKANEICAGDPKIKRASFRGDSGGPLVCKKV------AAGIVS 219 + CAG K + + GD+G + A GI+S Sbjct: 226 TVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILS 285 Query: 220 YGQNDGSTPRA-FTKVSTFLSWIKKTMKKS 248 + ++ + KV++ W++KT+ ++ Sbjct: 286 FDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 315 >2WIN-I nrPDB Length = 507 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 66/247 (26%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQ---EKM 86 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK EK Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 287 Query: 87 QQIIPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----R 132 I VV + HP YN + D+ L+KLK+K K ++P+ LP Sbjct: 288 DLEIEVV--LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 345 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVE-LTVQEDQK----CESYLKN------- 180 R +++ P C +L P Q+++ L V E++K E Y+KN Sbjct: 346 RALRLPPTTTCQQQK-EELLPA-------QDIKALFVSEEEKKLTRKEVYIKNGDKKGSC 397 Query: 181 --------YFDKANEI---------CAG--DPKIKRASFRGDSGGPLVCKK----VAAGI 217 +DK +I C G P + RGDSGGPL+ K + G+ Sbjct: 398 ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGV 457 Query: 218 VSYGQND 224 +S+G D Sbjct: 458 ISWGVVD 464 >4F4O-C nrPDB Length = 347 Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 119/265 (44%), Gaps = 49/265 (18%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + I+GG S P+ A +++ ++ + G LI E ++LT A N+ Sbjct: 96 PVDQVQRIMGGSLDAKGSFPWQA--KMISHHNLTS--GATLINEQWLLTTAK------NL 145 Query: 74 TLGAHNIKEQEKM----------QQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSS 123 LG N + + + +Q + + K+I HP ++ T+ DI L+KLK K + Sbjct: 146 RLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHP--DNSTV--DIGLIKLKQKVPVNE 201 Query: 124 AVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNY-- 181 V P+ LP ++ V G V YV+GWG+ + +++ L+ V L V + +KC Y + Sbjct: 202 RVMPICLPSKDY-VNVGLVGYVSGWGRNANL-NFTEHLKYVMLPVADQEKCVQYYEGSTV 259 Query: 182 --------------FDKANEICAGDPKIKRASFRGDSGGPLVCKK------VAAGIVSYG 221 + CAG K + + GD+G AAGI+S+ Sbjct: 260 PEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFD 319 Query: 222 QNDGSTPRA-FTKVSTFLSWIKKTM 245 ++ + + +V++ L WI+ T+ Sbjct: 320 KSCRTAEYGVYVRVTSILDWIQTTI 344 >1DLE-A nrPDB Length = 298 Score = 63.5 bits (153), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 66/247 (26%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQ---EKM 86 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK EK Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 80 Query: 87 QQIIPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----R 132 I VV + HP YN + D+ L+KLK+K K ++P+ LP Sbjct: 81 DLEIEVV--LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 138 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVE-LTVQEDQK----CESYLKN------- 180 R +++ P C +L P Q+++ L V E++K E Y+KN Sbjct: 139 RALRLPPTTTCQQQK-EELLPA-------QDIKALFVSEEEKKLTRKEVYIKNGDKKGSC 190 Query: 181 --------YFDKANEI---------CAG--DPKIKRASFRGDSGGPLVCKK----VAAGI 217 +DK +I C G P + RGDSGGPL+ K + G+ Sbjct: 191 ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGV 250 Query: 218 VSYGQND 224 +S+G D Sbjct: 251 ISWGVVD 257 >2OK5-A nrPDB Length = 752 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 66/247 (26%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQ---EKM 86 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK EK Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 531 Query: 87 QQIIPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----R 132 I VV + HP YN + D+ L+KLK+K K ++P+ LP Sbjct: 532 DLEIEVV--LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 589 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVE-LTVQEDQK----CESYLKN------- 180 R +++ P C +L P Q+++ L V E++K E Y+KN Sbjct: 590 RALRLPPTTTCQQQK-EELLPA-------QDIKALFVSEEEKKLTRKEVYIKNGDKKGSC 641 Query: 181 --------YFDKANEI---------CAG--DPKIKRASFRGDSGGPLVCKK----VAAGI 217 +DK +I C G P + RGDSGGPL+ K + G+ Sbjct: 642 ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGV 701 Query: 218 VSYGQND 224 +S+G D Sbjct: 702 ISWGVVD 708 >1PQ7-A nrPDB Length = 224 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 56/208 (26%), Positives = 87/208 (41%), Gaps = 15/208 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-SG---SKINVTLG 76 I+GG A P++ + +G CGG L+ + VLTAAHC SG S + G Sbjct: 1 IVGGTSASAGDFPFIVSI----SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + + + + + V++ HP+Y+ +ND+ +LKL + + L Sbjct: 57 SLS-RTSGGITSSLSSVRV--HPSYSGN--NNDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 137 VKPGDVCYVAGWGKLGPMGKYSD-TLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 G VAGWG G + L +V + + C + CAG Sbjct: 112 PVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSG 171 Query: 196 KRASFRGDSGGPLV-CKKVAAGIVSYGQ 222 + S +GDSGGP+V G VS+G Sbjct: 172 GKDSCQGDSGGPIVDSSNTLIGAVSWGN 199 >3RU4-E nrPDB Length = 96 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 35/93 (37%), Positives = 52/93 (55%), Gaps = 9/93 (9%) Query: 159 DTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAA--- 215 D LQ+ L + + C+ Y A ICAG + +S GDSGGPLVCKK A Sbjct: 4 DRLQQASLPLLSNTNCKKYWGTKIKDA-MICAGASGV--SSCMGDSGGPLVCKKNGAWTL 60 Query: 216 -GIVSYGQN--DGSTPRAFTKVSTFLSWIKKTM 245 GIVS+G + STP + +V+ ++W+++T+ Sbjct: 61 VGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >3H7T-A nrPDB Length = 235 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 98/237 (41%), Gaps = 21/237 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG----SKINVTLG 76 IIGG ++ P+ A ++DE CGG ++ +FV+TAA C S I++ G Sbjct: 1 IIGGKKSDITKEPW-AVGVLVDE---KPFCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 77 A--HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 + K M + I +V+ P N+ + M +KL K K + LP Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDK-----TTKKIELPSLL 111 Query: 135 VKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLK----NYFDKANEIC 189 +P V+GWG +YS L E TV + + CE K + + C Sbjct: 112 YDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFC 171 Query: 190 AGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGST-PRAFTKVSTFLSWIKKTM 245 AG + GD+G P V G+ SY + S P F +V ++ IK + Sbjct: 172 AGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDII 228 >1RIW-B nrPDB Length = 147 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/117 (33%), Positives = 56/117 (47%), Gaps = 15/117 (12%) Query: 50 CGGFLIREDFVLTAAHC----------SGSKINVTLGAHNIKEQEK-MQQIIPVVKIIPH 98 CG LI + +VLTAAHC + + + V +G H+ E+ +++I + KI H Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIH 87 Query: 99 PAYNSK-TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCY---VAGWGKL 151 P YN + + DI L+KLK S + P+ LP R Y V GWG L Sbjct: 88 PRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 144 >1BBR-H nrPDB Length = 150 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 15/115 (13%) Query: 50 CGGFLIREDFVLTAAHC----------SGSKINVTLGAHN-IKEQEKMQQIIPVVKIIPH 98 CG LI + +VLTAAHC + + V +G H+ + + K+++I + KI H Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIH 87 Query: 99 PAYNSK-TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK---PGDVCYVAGWG 149 P YN K + DI LLKLK + S + P+ LP + K G V GWG Sbjct: 88 PRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWG 142 >1AKS-B nrPDB Length = 98 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Query: 157 YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAG 216 Y LQ ++ V + C+S N IC G + + S +GDSGGP+VC G Sbjct: 6 YPSLLQCLKAPVLSNSSCKSSYPGQI-TGNMICVGFLQGGKDSCQGDSGGPVVCNGQLQG 64 Query: 217 IVS--YGQNDGSTPRAFTKVSTFLSWIKKTM 245 IVS YG + P +TKV +++WI++T+ Sbjct: 65 IVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >3F1S-B nrPDB Length = 283 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 8/138 (5%) Query: 46 GSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH-NIKEQEKMQQIIPVVKIIPHPAYNSK 104 G CGG +IRE+FVLT A CS N+T+ + N Q+ + +I + + H Y++ Sbjct: 75 GKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIKITHVHVHMRYDAD 132 Query: 105 TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKLGPMGKYSDTL 161 ND+ LL+L+ + A P+ P ++ + P ++GW + G ++L Sbjct: 133 AGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGT--DLGNSL 190 Query: 162 QEVELTVQEDQKCESYLK 179 +T+ E ++C L Sbjct: 191 TTRPVTLVEGEECGQVLN 208 >3H5C-B nrPDB Length = 317 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 8/138 (5%) Query: 46 GSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH-NIKEQEKMQQIIPVVKIIPHPAYNSK 104 G CGG +IRE+FVLT A CS N+T+ + N Q+ + +I + + H Y++ Sbjct: 116 GKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIKITHVHVHMRYDAD 173 Query: 105 TISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKLGPMGKYSDTL 161 ND+ LL+L+ + A P+ P ++ + P ++GW + G ++L Sbjct: 174 AGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGT--DLGNSL 231 Query: 162 QEVELTVQEDQKCESYLK 179 +T+ E ++C L Sbjct: 232 TTRPVTLVEGEECGQVLN 249 >2JET-C nrPDB Length = 99 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 13/99 (13%) Query: 156 KYSDTLQEVELTVQEDQKCESYLKNYFDKANEI--CAGDPKIKRASFRGDSGGPLVCKK- 212 K + LQ+ L + + C+ K++ K ++ CAG + S GDSGGPLVC+K Sbjct: 4 KTPEKLQQAALPIVSEADCK---KSWGSKITDVMTCAGASGVD--SCMGDSGGPLVCQKD 58 Query: 213 ---VAAGIVSYGQN--DGSTPRAFTKVSTFLSWIKKTMK 246 AGIVS+G STP +++V+ + W+++ ++ Sbjct: 59 GVWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILE 97 >2I6S-A nrPDB Length = 517 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 10/94 (10%) Query: 48 KKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKE-QEKMQQIIPVVKIIPHPAYNSKTI 106 + C G LI + +VLTAAHC + +L N+ + + + + + K + P ++ Sbjct: 255 ETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAK 314 Query: 107 SN---------DIMLLKLKSKAKRSSAVKPLNLP 131 N DI LLKL K K S+ +P+ LP Sbjct: 315 KNQGILEFYGDDIALLKLAQKVKMSTHARPICLP 348 >2HNT-F nrPDB Length = 105 Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust. Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 14/100 (14%) Query: 160 TLQEVELTVQEDQKCESYLKNYFDKANEICAG---DPKIKRASFRGDSGGPLVCKK---- 212 LQ V L + E C+ + N CAG D + + GDSGGP V K Sbjct: 5 VLQVVNLPIVERPVCKDSTRIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNN 63 Query: 213 --VAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ DG +T V WI+K + + Sbjct: 64 RWYQMGIVSWGEGCDRDGKYG-FYTHVFRLKKWIQKVIDQ 102 >1K93-A nrPDB Length = 510 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 154 MGKYSDTLQEVELTVQED-QKCESYLKNYFDKANEICAGDPKIKRASFRG 202 +G Y D+ + E +E +K YL +Y++ AN I + + K K + FRG Sbjct: 386 VGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRG 435 >1BBR-E nrPDB Length = 109 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 14/100 (14%) Query: 160 TLQEVELTVQEDQKCESYLKNYFDKANEICAG--DPKIKRA-SFRGDSGGPLVCKK---- 212 LQ V L + E C++ + N CAG + KR + GDSGGP V K Sbjct: 9 VLQVVNLPLVERPVCKASTRIRITD-NMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNN 67 Query: 213 --VAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ DG +T V WI+K + + Sbjct: 68 RWYQMGIVSWGEGCDRDGKYG-FYTHVFRLKKWIQKVIDR 106 >1LQU-A nrPDB Length = 456 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 11/63 (17%) Query: 144 YVAGWGKLGPMGKYSDTLQEVELTV----------QEDQKCESYLKNYFDK-ANEICAGD 192 YV GW K GP G ++ + TV +E +C+S+ +++ D+ A+ + A Sbjct: 355 YVVGWIKRGPTGVIGTNKKDAQDTVDTLIKNLGNAKEGAECKSFPEDHADQVADWLAARQ 414 Query: 193 PKI 195 PK+ Sbjct: 415 PKL 417 >1XFY-A nrPDB Length = 777 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 154 MGKYSDTLQEVELTVQED-QKCESYLKNYFDKANEICAGDPKIKRASFRG 202 +G Y D+ + E +E +K YL +Y++ AN I + + K K + FRG Sbjct: 653 VGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRG 702 >2HNT-C nrPDB Length = 70 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 11/17 (64%), Positives = 13/17 (76%) Query: 50 CGGFLIREDFVLTAAHC 66 CG LI + +VLTAAHC Sbjct: 28 CGASLISDRWVLTAAHC 44 >6O7W-d nrPDB Length = 345 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 24/55 (43%) Query: 143 CYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 C+ GW P + L+ + TV D Y KN FD A E+ + +I R Sbjct: 127 CHPLGWFDTLPTLSVATDLESLYETVLVDTPLAPYFKNCFDTAEELDDMNIEIIR 181 >5LAK-A nrPDB Length = 314 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 14/67 (20%) Query: 50 CGGFLIREDFVLTAAHCSGSK----INVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT 105 CGG L L HC+GS ++ T G NI K+Q HP+ T Sbjct: 153 CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKLQ----------HPSEIMIT 202 Query: 106 ISNDIML 112 ++N+I L Sbjct: 203 LNNEINL 209 >2AMU-A nrPDB Length = 143 Score = 26.9 bits (58), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 58 DFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHP 99 DF+ T + V +K+ EK+Q ++ V K IPHP Sbjct: 17 DFIKTEDFKKEKHVPVIEAPEKVKKDEKVQIVVTVGKEIPHP 58 >5GW5-z nrPDB Length = 546 Score = 26.6 bits (57), Expect = 9.6, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 157 YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 YS Q +L E + ++ LK D NE+C DP Sbjct: 253 YSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDP 289 >1HUS-A nrPDB Length = 155 Score = 26.6 bits (57), Expect = 9.8, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 5/36 (13%) Query: 91 PVVK--IIPHPAYNSKTIS---NDIMLLKLKSKAKR 121 PV K ++P P YNSK ++ N IM+ KSKA++ Sbjct: 5 PVAKRDVLPDPIYNSKLVTRLINKIMIDGKKSKAQK 40 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FI8-A nrPDB 359 e-100 1UTJ-A nrPDB 336 6e-93 5FXL-A nrPDB 329 6e-91 1F7Z-A nrPDB 328 1e-90 4AN7-A nrPDB 328 1e-90 1EUF-A nrPDB 324 2e-89 1IAU-A nrPDB 321 1e-88 4WWY-A nrPDB 319 9e-88 5C67-A nrPDB 318 1e-87 1A0J-A nrPDB 318 2e-87 3G01-A nrPDB 314 2e-86 6I44-A nrPDB 309 6e-85 1NN6-A nrPDB 309 9e-85 5TJX-A nrPDB 308 1e-84 3TK9-A nrPDB 302 7e-83 2TLD-E nrPDB 300 2e-82 5GVT-A nrPDB 300 3e-82 1FXY-A nrPDB 297 4e-81 2EEK-A nrPDB 293 6e-80 1SGF-G nrPDB 292 1e-79 4NFE-A nrPDB 288 2e-78 2F83-A nrPDB 288 2e-78 5UGG-A nrPDB 285 1e-77 3W94-A nrPDB 285 1e-77 4DUR-A nrPDB 284 2e-77 1BRU-P nrPDB 284 3e-77 1KYN-A nrPDB 282 1e-76 2RDL-A nrPDB 281 2e-76 3RP2-A nrPDB 280 3e-76 5MS3-A nrPDB 280 4e-76 4DGJ-A nrPDB 280 6e-76 1SPJ-A nrPDB 279 9e-76 3QUM-P nrPDB 278 1e-75 3T2N-A nrPDB 277 3e-75 1NPM-A nrPDB 277 3e-75 4H4F-A nrPDB 276 7e-75 1KIG-H nrPDB 275 1e-74 6AOD-C nrPDB 275 1e-74 2F91-A nrPDB 274 2e-74 3BSQ-A nrPDB 274 2e-74 1X7A-C nrPDB 274 2e-74 2PSX-A nrPDB 274 3e-74 3DFJ-A nrPDB 274 3e-74 1EKB-B nrPDB 274 3e-74 3LC3-A nrPDB 274 3e-74 3E0N-B nrPDB 273 3e-74 4MPW-A nrPDB 273 3e-74 1AO5-A nrPDB 273 4e-74 4GSO-A nrPDB 273 4e-74 6QHB-A nrPDB 271 2e-73 1TON-A nrPDB 271 2e-73 2CGA-A nrPDB 270 3e-73 1PYT-D nrPDB 270 5e-73 1FDP-A nrPDB 269 6e-73 1P57-B nrPDB 269 9e-73 1C5M-D nrPDB 269 9e-73 3S9B-A nrPDB 269 1e-72 2V35-A nrPDB 269 1e-72 5ZFH-A nrPDB 268 2e-72 1LTO-A nrPDB 268 2e-72 1SGF-A nrPDB 267 4e-72 1FUJ-A nrPDB 267 4e-72 3K65-B nrPDB 266 5e-72 3NXP-A nrPDB 266 6e-72 5FCR-A nrPDB 265 1e-71 4NZQ-A nrPDB 265 2e-71 3P8G-A nrPDB 264 2e-71 2AIQ-A nrPDB 264 3e-71 1MKW-K nrPDB 264 3e-71 1ELT-A nrPDB 263 3e-71 4E7N-A nrPDB 263 5e-71 1BDA-A nrPDB 263 6e-71 1FIZ-A nrPDB 262 1e-70 4Z6A-H nrPDB 262 1e-70 1ORF-A nrPDB 262 2e-70 1MZD-A nrPDB 260 3e-70 1FIW-A nrPDB 258 2e-69 2OQ5-A nrPDB 258 2e-69 1VR1-H nrPDB 258 2e-69 1FON-A nrPDB 258 2e-69 1OP0-A nrPDB 257 2e-69 1A5I-A nrPDB 257 3e-69 2OCV-B nrPDB 257 4e-69 1YC0-A nrPDB 257 4e-69 1GVZ-A nrPDB 256 6e-69 1ETT-H nrPDB 255 1e-68 2BDH-A nrPDB 254 3e-68 1SC8-U nrPDB 253 4e-68 5LHN-A nrPDB 252 8e-68 2R0L-A nrPDB 252 1e-67 3S69-A nrPDB 252 1e-67 1BQY-A nrPDB 251 2e-67 3F6U-H nrPDB 251 3e-67 4XDE-A nrPDB 250 4e-67 4Q7Y-A nrPDB 249 1e-66 5TO3-B nrPDB 245 1e-65 2OLG-A nrPDB 243 7e-65 2ZKS-A nrPDB 240 4e-64 5LPF-A nrPDB 240 6e-64 4IW4-E nrPDB 238 2e-63 4KKD-A nrPDB 238 2e-63 1AZZ-A nrPDB 238 2e-63 1Q3X-A nrPDB 237 3e-63 1GPZ-A nrPDB 236 5e-63 5XRF-A nrPDB 236 6e-63 2XXL-A nrPDB 236 6e-63 4IGD-A nrPDB 236 8e-63 1ELV-A nrPDB 235 2e-62 1MD7-A nrPDB 235 2e-62 1ZJK-A nrPDB 235 2e-62 4BXW-A nrPDB 234 2e-62 4DJZ-B nrPDB 234 3e-62 1EQ9-A nrPDB 233 7e-62 1YM0-A nrPDB 233 8e-62 2QY0-B nrPDB 232 1e-61 5UBM-A nrPDB 231 2e-61 1AE5-A nrPDB 231 2e-61 2XRC-A nrPDB 229 1e-60 4FXG-H nrPDB 229 1e-60 4J1Y-A nrPDB 228 1e-60 5KWM-A nrPDB 226 7e-60 5O32-I nrPDB 224 3e-59 1PPF-E nrPDB 222 9e-59 2B9L-A nrPDB 218 1e-57 2HLC-A nrPDB 210 4e-55 2ASU-B nrPDB 208 3e-54 3I77-A nrPDB 207 4e-54 4X0L-C nrPDB 207 4e-54 4WJG-C nrPDB 206 8e-54 1PQ7-A nrPDB 205 2e-53 4LK4-A nrPDB 205 2e-53 3BEU-A nrPDB 204 2e-53 4F4O-C nrPDB 204 2e-53 6BQM-A nrPDB 202 1e-52 1SI5-H nrPDB 199 8e-52 2FMJ-A nrPDB 199 8e-52 5XW8-A nrPDB 192 1e-49 3H7O-A nrPDB 190 5e-49 1M9U-A nrPDB 188 1e-48 2PKA-B nrPDB 183 4e-47 3H7T-A nrPDB 174 2e-44 3VGC-B nrPDB 166 1e-41 2JET-B nrPDB 165 2e-41 1RIW-B nrPDB 158 2e-39 1BBR-H nrPDB 154 4e-38 2WIN-I nrPDB 151 2e-37 1DLE-A nrPDB 150 5e-37 2OK5-A nrPDB 148 2e-36 1AKS-B nrPDB 144 4e-35 2KAI-A nrPDB 117 6e-27 1EPT-B nrPDB 113 6e-26 3F1S-B nrPDB 112 1e-25 3RU4-E nrPDB 111 4e-25 3H5C-B nrPDB 110 6e-25 2JET-C nrPDB 107 5e-24 Sequences not found previously or not previously below threshold: 1BBR-E nrPDB 112 1e-25 2HNT-F nrPDB 112 2e-25 2I6S-A nrPDB 103 9e-23 2HNT-E nrPDB 86 2e-17 2HNT-C nrPDB 78 3e-15 1P3E-A nrPDB 40 0.001 2PFE-A nrPDB 38 0.005 2EA3-A nrPDB 36 0.014 2OUA-A nrPDB 36 0.023 5ILB-A nrPDB 36 0.023 4FLN-A nrPDB 36 0.023 2SFA-A nrPDB 34 0.049 2SGA-A nrPDB 33 0.10 3LT3-A nrPDB 32 0.17 3W95-A nrPDB 32 0.18 4FVB-A nrPDB 32 0.18 2HRV-A nrPDB 31 0.62 3H7V-A nrPDB 31 0.63 5JYK-A nrPDB 30 0.85 5XIP-A nrPDB 30 0.99 4XZB-A nrPDB 30 1.2 5ILA-A nrPDB 30 1.2 4V1Y-A nrPDB 29 1.9 4NCX-A nrPDB 29 2.2 1HPG-A nrPDB 29 2.4 2M5T-A nrPDB 29 2.4 5XIG-A nrPDB 28 3.2 1DUE-A nrPDB 28 4.4 4NSY-A nrPDB 28 5.1 4DP3-A nrPDB 27 5.4 3DGA-C nrPDB 27 5.4 2CTL-A nrPDB 27 5.5 1CDO-A nrPDB 27 6.1 5NZU-C nrPDB 27 6.7 4B6E-A nrPDB 27 6.7 6FE6-A nrPDB 27 7.7 4NWK-A nrPDB 27 7.9 6C2N-A nrPDB 27 8.2 4U01-A nrPDB 27 8.5 4K8B-A nrPDB 27 8.6 >1FI8-A nrPDB Length = 228 Score = 359 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 227/228 (99%), Positives = 227/228 (99%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 248 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 228 >1UTJ-A nrPDB Length = 242 Score = 336 bits (862), Expect = 6e-93, Method: Composition-based stats. Identities = 90/249 (36%), Positives = 129/249 (51%), Gaps = 10/249 (4%) Query: 1 MKLLLLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFV 60 M L+ +L A TE +I+GG+E KP+S+P+ L SG CGG L+ E++V Sbjct: 1 MISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLN-----SGYHFCGGSLVNENWV 55 Query: 61 LTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 ++AAHC S++ V LG HNIK E +Q I ++I HP Y+S I NDIML+KL A Sbjct: 56 VSAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPAT 115 Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN 180 ++ V+P+ LP G +C V+GWG S+ LQ + + + C + Sbjct: 116 LNTYVQPVALPTSC--APAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG 173 Query: 181 YFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFL 238 A CAG + + S +GDSGGP+VC G+VS+G P + KV F Sbjct: 174 MITNA-MFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFN 232 Query: 239 SWIKKTMKK 247 W+ TM Sbjct: 233 DWLTSTMAS 241 >5FXL-A nrPDB Length = 246 Score = 329 bits (845), Expect = 6e-91, Method: Composition-based stats. Identities = 94/250 (37%), Positives = 134/250 (53%), Gaps = 12/250 (4%) Query: 3 LLLLLLSFSLA-PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVL 61 + L LL ++A P + +I+GG+ ++ PY L SG CGG LI +V+ Sbjct: 5 IFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLN-----SGYHFCGGSLINSQWVV 59 Query: 62 TAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKR 121 +AAHC S I V LG NI E +Q I K I HP+YNS T++NDIML+KLKS A Sbjct: 60 SAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASL 119 Query: 122 SSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKN 180 +S V ++LP G C ++GWG G Y D L+ ++ + D C+S Sbjct: 120 NSRVASISLPTSCAS--AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG 177 Query: 181 YFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFL 238 +N CAG + + S +GDSGGP+VC GIVS+G + P +TKV ++ Sbjct: 178 QI-TSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYV 236 Query: 239 SWIKKTMKKS 248 SWIK+T+ + Sbjct: 237 SWIKQTIASN 246 >1F7Z-A nrPDB Length = 233 Score = 328 bits (842), Expect = 1e-90, Method: Composition-based stats. Identities = 84/238 (35%), Positives = 122/238 (51%), Gaps = 11/238 (4%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + I+GG+ + +S PY L SG CGG LI + +V++AAHC S+I V Sbjct: 4 PVDDDDAIVGGYTCQENSVPYQVSLN-----SGYHFCGGSLINDQWVVSAAHCYKSRIQV 58 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q + KII HP ++ KT++NDIML+KL S K ++ V + LP Sbjct: 59 RLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 134 NVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 G C ++GWG G D LQ ++ + CE+ N +C G Sbjct: 119 C--APAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKI-TDNMVCVGF 175 Query: 193 PKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + + S +GDSGGP+VC GIVS+G P +TKV ++ WI+ T+ + Sbjct: 176 LEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 328 bits (841), Expect = 1e-90, Method: Composition-based stats. Identities = 91/238 (38%), Positives = 126/238 (52%), Gaps = 11/238 (4%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + +I+GG+ +S PY L SGS CGG LI +V++AAHC S+I V Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSLN-----SGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V ++LPR Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 134 NVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 G C ++GWG G Y LQ ++ V D C+S N IC G Sbjct: 117 C--AAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQI-TGNMICVGF 173 Query: 193 PKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + + S +GDSGGP+VC GIVS+G + P +TKV +++WI++T+ + Sbjct: 174 LEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1EUF-A nrPDB Length = 227 Score = 324 bits (831), Expect = 2e-89, Method: Composition-based stats. Identities = 140/227 (61%), Positives = 171/227 (75%), Gaps = 2/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMA+L + S CGGFL+REDFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFL-LFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E+E+ QQ+IPV + IPHP YN +T++NDIMLLKL KA + V P+NLPR +VKPG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG+LG +D LQEV+L VQ ++KC + KNY +ICAGDP ++ SF Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYI-PFTQICAGDPSKRKNSF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 GDSGGPLVC VA GIVSYG+NDG+TP +T++S+FLSWI TM++ Sbjct: 179 SGDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMRR 225 >1IAU-A nrPDB Length = 227 Score = 321 bits (824), Expect = 1e-88, Method: Composition-based stats. Identities = 159/227 (70%), Positives = 186/227 (81%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMAYL I D+ S +CGGFLIR+DFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLK-RCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQE QQ IPV + IPHPAYN K SNDIMLL+L+ KAKR+ AV+PL LP +VKPG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 C VAGWG+ P+GK+S TLQEV++TVQED+KCES L++Y+D E+C GDP+IK+ SF Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGPLVC KVA GIVSYG+N+G PRA TKVS+F+ WIKKTMK+ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 226 >4WWY-A nrPDB Length = 224 Score = 319 bits (817), Expect = 9e-88, Method: Composition-based stats. Identities = 87/231 (37%), Positives = 124/231 (53%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ + +S PY L SG CGG LI E +V++A HC S+I V LG HNI Sbjct: 1 IVGGYNCEENSVPYQVSLN-----SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + E +Q I KII HP Y+ KT++NDIML+KL S+A ++ V ++LP G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA--PPATG 113 Query: 141 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D LQ ++ V KCE+ +N C G + + S Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFLEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + DSGGP+VC G+VS+G + P +TKV ++ WIK T+ + Sbjct: 173 CQRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >5C67-A nrPDB Length = 224 Score = 318 bits (816), Expect = 1e-87, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 122/231 (52%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ + +S PY L SGS CGG LI E +V++AAHC ++I V LG HNI Sbjct: 1 IVGGYTCEENSLPYQVSLN-----SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K E +Q I KII HP YN T+ NDIML+KL S A ++ V ++LP G Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--PPAAG 113 Query: 141 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D L+ ++ V +C++ + C G + + S Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKI-TNSMFCVGFLEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 + D+GGP+VC G+VS+G + P +TKV ++ WIK T+ + Sbjct: 173 CQRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >1A0J-A nrPDB Length = 223 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 92/231 (39%), Positives = 124/231 (53%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+E + +S Y A LQ SG CGG LI +V++AAHC S+I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E +Q I VK+I HP+YNS+ + NDIML+KL A +S V + LP G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCAS--SG 113 Query: 141 DVCYVAGWGKLG-PMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C V+GWG L Y DTL+ ++L + C S +N CAG + + S Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQI-TSNMFCAGFMEGGKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 +GDSGGP+VC G+VS+G + P +TKV + SWI TM + Sbjct: 173 CQGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >3G01-A nrPDB Length = 227 Score = 314 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 151/226 (66%), Positives = 176/226 (77%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG+E PHSRPYMAY + + CGGFL+R+ FVLTAAHC G + VTLGAHNI Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K +E+ QQIIPV K IPHP YN SNDIMLLKL AKR+ AV+PLNLPRRN VKPG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 D CYVAGWGK+ P G++ TL EV+LTVQ+DQ CES ++ +++ANEIC GD KIK ASF Sbjct: 121 DECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASF 180 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 RGDSGGPLVCK+ AAGIVSYGQ DGS P+ FT+V +F+SWIKKTMK Sbjct: 181 RGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >6I44-A nrPDB Length = 627 Score = 309 bits (793), Expect = 6e-85, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 116/250 (46%), Gaps = 12/250 (4%) Query: 10 FSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG- 68 S+ + I+GG ++ P+ LQ+ CGG LI +VLTAAHC Sbjct: 369 NSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDG 427 Query: 69 ----SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + G + + K + +II H Y ++DI L+KL++ + + Sbjct: 428 LPLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEF 487 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDK 184 KP+ LP + C+V GWG G+ + LQ+V + + +++C+ ++Y Sbjct: 488 QKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKIT 547 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGST--PRAFTKVSTFL 238 +CAG + + + +GD+GGPLVCK GI S+G+ P +TKV+ ++ Sbjct: 548 QRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYM 607 Query: 239 SWIKKTMKKS 248 WI + + S Sbjct: 608 DWILEKTQSS 617 >1NN6-A nrPDB Length = 228 Score = 309 bits (791), Expect = 9e-85, Method: Composition-based stats. Identities = 119/230 (51%), Positives = 156/230 (67%), Gaps = 2/230 (0%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH 78 GEIIGG E KPHSRPYMAYL+I+ SK CGGFLIR +FVLTAAHC+G I VTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 NI E+E Q + V+K HP YN+ T+ +DIMLLKLK KA + AV L P + V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 139 PGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 PG +C VAGWG+ G + SDTLQEV+L + + Q C + FD ++C G+P+ ++ Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF--RDFDHNLQLCVGNPRKTKS 178 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 248 +F+GDSGGPL+C VA GIVSYG++D P FT++S + WI + ++ + Sbjct: 179 AFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 228 >5TJX-A nrPDB Length = 263 Score = 308 bits (790), Expect = 1e-84, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 117/250 (46%), Gaps = 12/250 (4%) Query: 10 FSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG- 68 S+ + I+GG E+ P+ LQ+ CGG LI +VLTAAHC Sbjct: 5 NSVCTTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDG 63 Query: 69 ----SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + G + + K + +II H Y ++DI L+KL++ + + Sbjct: 64 LPLQDVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEF 123 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDK 184 KP++LP + C+V GWG G+ + LQ+V + + +++C+ ++Y Sbjct: 124 QKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 183 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGST--PRAFTKVSTFL 238 +CAG + + + +GDSGGPLVCK GI S+G+ P +TKV+ ++ Sbjct: 184 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYM 243 Query: 239 SWIKKTMKKS 248 WI + + S Sbjct: 244 DWILEKTQSS 253 >3TK9-A nrPDB Length = 226 Score = 302 bits (775), Expect = 7e-83, Method: Composition-based stats. Identities = 141/227 (62%), Positives = 170/227 (74%), Gaps = 2/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGGHEAKPHSRPYMA++Q + E S K+CGG L+R+DFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKS-RKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 KEQE+ QQ IPV + IPHPAYN K SN+IMLL+L+ KAK ++AV+PL LP +VKPG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG + M + TLQEV LTVQ+D +CE + +A EIC GDPK + F Sbjct: 120 QLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGPLVCK VA GI+SYG G+ P + KVS FL WIK+TMK+ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKR 225 >2TLD-E nrPDB Length = 220 Score = 300 bits (770), Expect = 2e-82, Method: Composition-based stats. Identities = 89/230 (38%), Positives = 122/230 (53%), Gaps = 12/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+ ++ PY L SG CGG LI +V++AAHC S I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSLN-----SGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 E +Q I K I HP+YNS T++NDIML+KLKS A +S V ++LP G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--AG 113 Query: 141 DVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C ++GWG G Y D L+ ++ + D C+S +N CAG S Sbjct: 114 TQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TSNMFCAGLEGG--DS 170 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDG-STPRAFTKVSTFLSWIKKTMKKS 248 +GDSGGP+VC GIVS+G + P +TKV ++SWIK+T+ + Sbjct: 171 CQGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTIASN 220 >5GVT-A nrPDB Length = 250 Score = 300 bits (769), Expect = 3e-82, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 112/239 (46%), Gaps = 12/239 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-----GSKINVTL 75 I+GG A P+ LQ+ S + CGG +I +VLTAAHC + Sbjct: 1 IVGGTNASLGEWPWQVSLQVKL-VSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G ++ E K + ++I H Y + DI L+KL++ + KP++LP + Sbjct: 60 GILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 C+V GWG G+ + LQ+ + + +++C+ ++Y ICAG + Sbjct: 120 TNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 196 KRASFRGDSGGPLVCK----KVAAGIVSYGQNDGST--PRAFTKVSTFLSWIKKTMKKS 248 + +GDSGGPLVCK GI S+G+ P +TKVS ++ WI + + S Sbjct: 180 GTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSS 238 >1FXY-A nrPDB Length = 228 Score = 297 bits (760), Expect = 4e-81, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 111/233 (47%), Gaps = 11/233 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG+ K P+ A L CGG ++ E ++LTAAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALL---INEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 N +++E + + V +I H + +T DI +L+LK+ V P +LP Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--PPA 115 Query: 139 PGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 G C ++GWG G Y D LQ ++ V KCE+ +N C G + + Sbjct: 116 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFLEGGK 174 Query: 198 ASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 S +GDSGGP+VC G+VS+G + P +TKV ++ WIK T+ + Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >2EEK-A nrPDB Length = 220 Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats. Identities = 78/228 (34%), Positives = 112/228 (49%), Gaps = 10/228 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG+E HS+ + L SG CGG L+ +D+V++AAHC S + V LG H+I Sbjct: 1 IVGGYECTKHSQAHQVSLN-----SGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHI 55 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + E +Q I +I HP Y+S I+NDIML+KL A + V + LP Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTEC--AADA 113 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C V+GWG D LQ + L + C + + CAG + + S Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMI-TQSMFCAGYLEGGKDSC 172 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGST--PRAFTKVSTFLSWIKKTMK 246 +GDSGGP+VC V G+VS+G P + KV W++ TM Sbjct: 173 QGDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTMA 220 >1SGF-G nrPDB Length = 237 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 83/243 (34%), Positives = 122/243 (50%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG + + +S+P+ + +Y CGG L+ ++VLTAAHC V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQY----LCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSK-----------TISNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V K IPHP +N SND+MLL+L A + VKP+ Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP K+ G C +GWG + P +++D L V L + ++ C A + Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDA-ML 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGST---PRAFTKVSTFLSWIKKTM 245 CAG+ + + +GDSGGPL+C V GI S+G P +TK++ F SWIK TM Sbjct: 174 CAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTM 233 Query: 246 KKS 248 K+ Sbjct: 234 AKN 236 >4NFE-A nrPDB Length = 237 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 84/243 (34%), Positives = 113/243 (46%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ + G CGG L+ +VLTAAHC V LG HN+ Sbjct: 1 IVGGWECEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 E E Q +PV PHP YN + S+D+MLL+L AK + VK L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGKY-SDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + + G CY +GWG + P +LQ V L + + C + Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKV-TEFML 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG---STPRAFTKVSTFLSWIKKTM 245 CAG + + GDSGGPLVC V GI S+G P +TKV + WIK T+ Sbjct: 174 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 233 Query: 246 KKS 248 + Sbjct: 234 AAN 236 >2F83-A nrPDB Length = 625 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 65/245 (26%), Positives = 107/245 (43%), Gaps = 12/245 (4%) Query: 13 APKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----- 67 I+GG + P+ L + CGG +I ++LTAAHC Sbjct: 380 CTTKIKPRIVGGTASVRGEWPWQVTLHTTSP-TQRHLCGGSIIGNQWILTAAHCFYGVES 438 Query: 68 GSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKP 127 + V G N E ++ V +II H Y DI LLKL++ + + +P Sbjct: 439 PKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRP 498 Query: 128 LNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANE 187 + LP + + C+V GWG K +TLQ+ ++ + +++C+ + + Sbjct: 499 ICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKM 558 Query: 188 ICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWI 241 ICAG + + + +GDSGGPL CK GI S+G+ P +T V ++ WI Sbjct: 559 ICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 Query: 242 KKTMK 246 + + Sbjct: 619 LEKTQ 623 >5UGG-A nrPDB Length = 251 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 22/249 (8%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 + PK G ++GG A PHS P+ L+ G CGG LI ++VLTAAHC Sbjct: 13 VEPKKCPGRVVGGCVAHPHSWPWQVSLRT---RFGMHFCGGTLISPEWVLTAAHCLEKSP 69 Query: 67 SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVK 126 S V LGAH E Q I V ++ P DI LLKL S A + V Sbjct: 70 RPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVI 123 Query: 127 PLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKA 185 P LP N V C++ GWG+ + L+E +L V E++ C Y N ++ Sbjct: 124 PACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQS 182 Query: 186 NEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLS 239 E+CAG S +GDSGGPLVC K + G+ S+G + P + +VS F++ Sbjct: 183 TELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVT 242 Query: 240 WIKKTMKKS 248 WI+ M+ + Sbjct: 243 WIEGVMRNN 251 >3W94-A nrPDB Length = 235 Score = 285 bits (729), Expect = 1e-77, Method: Composition-based stats. Identities = 77/239 (32%), Positives = 117/239 (48%), Gaps = 17/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK------INVT 74 ++GG A+ + P+M L + G CG LI D++LTAAHC K + Sbjct: 1 VVGGVNAEKGAWPWMVSLH----WRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 75 LGAHNIKEQEKMQ-QIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG H + QI V +II + YN +T DI ++ L+ + V P+ L Sbjct: 57 LGLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASE 116 Query: 134 NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 + G C++AGWG+ G D LQE E+ + + +C+ L Y ++ +CAG P Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYP 176 Query: 194 KIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMK 246 + S +GDSGGPL+C + G+ S+G G P A+ +VS F SWI +T + Sbjct: 177 EGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAETRR 235 >4DUR-A nrPDB Length = 791 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 22/249 (8%) Query: 12 LAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----- 66 + PK G ++GG A PHS P+ L+ G CGG LI ++VLTAAHC Sbjct: 553 VEPKKCPGRVVGGCVAHPHSWPWQVSLRT---RFGMHFCGGTLISPEWVLTAAHCLEKSP 609 Query: 67 SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVK 126 S V LGAH E Q I V ++ P DI LLKL S A + V Sbjct: 610 RPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVI 663 Query: 127 PLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKA 185 P LP N V C++ GWG+ + L+E +L V E++ C Y N ++ Sbjct: 664 PACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQS 722 Query: 186 NEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLS 239 E+CAG S +GDSGGPLVC K + G+ S+G + P + +VS F++ Sbjct: 723 TELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVT 782 Query: 240 WIKKTMKKS 248 WI+ M+ + Sbjct: 783 WIEGVMRNN 791 >1BRU-P nrPDB Length = 241 Score = 284 bits (727), Expect = 3e-77, Method: Composition-based stats. Identities = 83/242 (34%), Positives = 116/242 (47%), Gaps = 15/242 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK--INVTLGAH 78 ++GG +A+P+S P+ LQ CGG L+ + +VLTAAHC S V LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTI--SNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 ++ E + V K++ H +NS + NDI LLKL S + ++ LP Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKI 195 + VCYV GWG+L G D LQ+ +L V + C K N ICAG Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGD-G 179 Query: 196 KRASFRGDSGGPLVC-----KKVAAGIVSYGQNDGS----TPRAFTKVSTFLSWIKKTMK 246 +S GDSGGPL C + GIVS+G + G P FT+VS ++ WI + Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIA 239 Query: 247 KS 248 + Sbjct: 240 NN 241 >1KYN-A nrPDB Length = 235 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 125/227 (55%), Positives = 164/227 (72%), Gaps = 3/227 (1%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E++PHSRPYMAYLQI +G +CGGFL+REDFVLTAAHC GS INVTLGAHNI Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSP-AGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNI 59 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + +E QQ I + I HP YN +TI NDIMLL+L + +R+ V P+ LPR ++PG Sbjct: 60 QRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C VAGWG++ M + +DTL+EV+L VQ D++C +Y D +IC GD + ++A+F Sbjct: 120 TLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSY-DPRRQICVGDRRERKAAF 177 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 +GDSGGPL+C VA GIVSYG++ G P FT+VS+FL WI+ TM+ Sbjct: 178 KGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRS 224 >2RDL-A nrPDB Length = 226 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 100/228 (43%), Positives = 141/228 (61%), Gaps = 2/228 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E +PH+RPYMAYL+I+ + C GFLIR +FV+TAAHC+G I V LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 K +E Q + V K PHP Y+ + + NDIMLLKLK KA + V L + ++ + PG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 VC GWG+ SDTLQEV++ + + Q C+ + F + ++C G+PK R + Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHF--EDFHQEPQLCVGNPKKIRNVY 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS 248 +GDSGGPL+C +A GI SY + P FT++S + WI K ++++ Sbjct: 179 KGDSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILREN 226 >3RP2-A nrPDB Length = 224 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 110/225 (48%), Positives = 144/225 (64%), Gaps = 2/225 (0%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E+ PHSRPYMA+L I+ E CGGFLI FVLTAAHC G +I V LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 +++E QQ I V K I H +YNS +DIMLLKL+ K + + AV + LP + + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 141 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 200 +C+ AGWGK G S TL+EVEL + +++ C Y Y++ ++C G P RA+F Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDY--RYYEYKFQVCVGSPTTLRAAF 178 Query: 201 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTM 245 GDSGGPL+C VA GIVSYG D P FT+VST++ WI + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVI 223 >5MS3-A nrPDB Length = 228 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 88/232 (37%), Positives = 127/232 (54%), Gaps = 15/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GGHE +PHS+P+ A L CGG L+ ++VLTAAHC K V LG H++ Sbjct: 1 VLGGHECQPHSQPWQAALF----QGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNS---KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + ++ +Q IPVV+ IPHP YNS + ++D+MLL+L+ +A S VKP++L Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT-- 114 Query: 138 KPGDVCYVAGWGK-LGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 +PG C V+GWG P + DTL E+ + +KCE +CAG K Sbjct: 115 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI-TDGMVCAGSSK-G 172 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYGQNDGS---TPRAFTKVSTFLSWIKKTM 245 + +GDSGGPLVC GI S+G + P +T + +L WIKK + Sbjct: 173 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >4DGJ-A nrPDB Length = 235 Score = 280 bits (716), Expect = 6e-76, Method: Composition-based stats. Identities = 75/237 (31%), Positives = 121/237 (51%), Gaps = 19/237 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS------GSKINVT 74 I+GG +AK + P++ L D CG L+ D++++AAHC SK Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDD----RLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 75 LGAHNIKEQEKMQQIIP--VVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 LG H +K Q +P + +I+ +P YN + NDI ++ L+ K + ++P++LP Sbjct: 57 LGLH-MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPE 115 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 N PG C +AGWG + G +D LQE ++ + +++C+ + Y N ICAG Sbjct: 116 ENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY 175 Query: 193 PKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKK 243 + S +GDSGGPL+C + AG+ S+G + P + +VS F WI+ Sbjct: 176 EEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQS 232 >1SPJ-A nrPDB Length = 238 Score = 279 bits (714), Expect = 9e-76, Method: Composition-based stats. Identities = 75/244 (30%), Positives = 119/244 (48%), Gaps = 23/244 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ A L + CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ----CGGILVHRQWVLTAAHCISDNYQLWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYN-----------SKTISNDIMLLKLKSKA-KRSSAVKPL 128 + E Q + V + PHP +N + S+D+MLL+L A + AVK + Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANE 187 LP +V G C +GWG + P + D LQ V+L + + +C+ Sbjct: 117 ELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDF-M 173 Query: 188 ICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKT 244 +C G + + + GDSGGPL+C V G+ S+G + P +V +++ WI+ T Sbjct: 174 LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDT 233 Query: 245 MKKS 248 + ++ Sbjct: 234 IAEN 237 >3QUM-P nrPDB Length = 237 Score = 278 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 117/243 (48%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG E + HS+P+ + G CGG L+ +VLTAAHC +K + LG H++ Sbjct: 1 IVGGWECEKHSQPWQVLV----ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 E Q+ V PHP Y+ + S+D+MLL+L A+ + AVK ++ Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + + G CY +GWG + P LQ V+L V + C K + Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF-ML 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG---STPRAFTKVSTFLSWIKKTM 245 CAG +++ GDSGGPLVC V GI S+G P +TKV + WIK T+ Sbjct: 174 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 Query: 246 KKS 248 + Sbjct: 234 VAN 236 >3T2N-A nrPDB Length = 372 Score = 277 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 76/255 (29%), Positives = 110/255 (43%), Gaps = 29/255 (11%) Query: 15 KTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG------ 68 K I+GG + P+ L+ Y G+ CGG L+ D+VLTAAHC Sbjct: 112 KLPVDRIVGGRDTSLGRWPWQVSLR----YDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 167 Query: 69 SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNS------KTISNDIMLLKLKSKAKRS 122 S+ V GA +Q + V ++ H Y + SNDI L+ L S + Sbjct: 168 SRWRVFAGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 225 Query: 123 SAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNY 181 ++P+ LP + G +C V GWG G+ + LQE + + + C + Sbjct: 226 EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN 285 Query: 182 FDKANEICAGDPKIKRASFRGDSGGPLVC--------KKVAAGIVSYGQND--GSTPRAF 231 K CAG P+ + +GDSGGP VC + GIVS+G P + Sbjct: 286 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVY 345 Query: 232 TKVSTFLSWIKKTMK 246 TKVS F WI + +K Sbjct: 346 TKVSDFREWIFQAIK 360 >1NPM-A nrPDB Length = 225 Score = 277 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 83/233 (35%), Positives = 122/233 (52%), Gaps = 15/233 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+ G E PHS+P+ A L + CGG L+ + +VLTAAHC K +V LG H++ Sbjct: 1 ILEGRECIPHSQPWQAALFQGE----RLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAY---NSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + +++ +Q I V + I HP Y N + S+DIML++L++ A VKP+ L N+ Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLCP 114 Query: 138 KPGDVCYVAGWGK-LGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 K G C ++GWG P + +TL E+ + KCE +CAG Sbjct: 115 KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKI-TEGMVCAG-SSNG 172 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 + +GDSGGPLVC + GI S+G P +TK+ + +WIKKTM Sbjct: 173 ADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMD 225 >4H4F-A nrPDB Length = 249 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 120/239 (50%), Gaps = 14/239 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK--INVTLGAH 78 ++GG +A+PHS P+ LQ + + CGG LI +FVLTAAHC + V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 NIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 N++ E E+ + V I H +N+ + NDI L+KL + S ++ LP ++ + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 138 KPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES-YLKNYFDKANEICAGDPKIK 196 CYV GWG+L G +D LQ+ V + C + K +CAG + Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 179 Query: 197 RASFRGDSGGPLVCK-----KVAAGIVSY----GQNDGSTPRAFTKVSTFLSWIKKTMK 246 ++ GDSGGPL C+ GIVS+ G N P +T+VS ++ WI + M+ Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >1KIG-H nrPDB Length = 241 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 108/237 (45%), Gaps = 15/237 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG + P+ A L CGG ++ E +VLTAAHC + V +G Sbjct: 1 IVGGRDCAEGECPWQALLV---NEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN---V 135 N +++E + V + H + +T DI +L+LK+ + V P LP ++ Sbjct: 58 NTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEA 117 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 + V+G+G+ G+ S TL+ +E+ + C+ ++ N CAG Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCK-LSSSFTITPNMFCAGYDTQ 176 Query: 196 KRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTP--RAFTKVSTFLSWIKKTMK 246 + +GDSGGP V + GIVS+G+ +TKVS FL WI K MK Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >6AOD-C nrPDB Length = 245 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 108/237 (45%), Gaps = 12/237 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-----GSKINVTL 75 I+GG + P+ L + CGG +I ++LTAAHC + V Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSP-TQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G E ++ V +II H Y DI LLKL++ + + + +P++LP + Sbjct: 60 GILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 + C+V GWG K +TLQ+ ++ + +++C+ + + ICAG + Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 196 KRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMK 246 + + +GD+GGPL CK GI S+G+ P +T V ++ WI + + Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQ 236 >2F91-A nrPDB Length = 237 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 76/235 (32%), Positives = 106/235 (45%), Gaps = 15/235 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-------GSKINV 73 I+GG +A PY Q CG + E++ +TA HC S + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 G ++ E +QII V KII H ++ + NDI LLKL + V P+ LP + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 134 NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 GDV V GWG G D LQ+V + + D+ C + + ICAG P Sbjct: 121 GHTA-TGDV-IVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 194 KIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDGS--TPRAFTKVSTFLSWIK 242 + + S +GDSGGPL AGIVS+G P +T+VS + WIK Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >3BSQ-A nrPDB Length = 227 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 83/230 (36%), Positives = 117/230 (50%), Gaps = 13/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G S P+ L CGG L+ E +VLTAAHC ++ V LG+ + Sbjct: 1 IIDGAPCARGSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 ++ Q I K HP Y+++T ND+ML+KL S+A+ SS VK + LP R PG Sbjct: 57 GDR--RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 112 Query: 141 DVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C V+GWG P + L V++ + Q C K+ + + +CAG P K+ + Sbjct: 113 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIPDSKKNA 171 Query: 200 FRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPLVC+ G+VS+G + P +T+V F WI TMK Sbjct: 172 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1X7A-C nrPDB Length = 235 Score = 274 bits (701), Expect = 2e-74, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 122/239 (51%), Gaps = 19/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS--KINVTLGAH 78 I+GG AKP P+ L + CGG +I E +V+TAAHC KI V G + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDA----FCGGSIINEKWVVTAAHCIEPGVKITVVAGEY 56 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNS--KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 N +E E +Q V++ IPH +YN+ S+DI LL+L +S V P+ + + Sbjct: 57 NTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYT 116 Query: 137 ---VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 +K G YV+GWG++ G+ + LQ +++ + + C K + +N CAG Sbjct: 117 NIFLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTK-FTIYSNMFCAGFH 174 Query: 194 KIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMK 246 + + S +GDSGGP V + GI+S+G+ +TKVS +++WIK+ K Sbjct: 175 EGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >2PSX-A nrPDB Length = 227 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 117/233 (50%), Gaps = 12/233 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G + H++P+ A L + CG L+ ++LTAAHC V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLL---RPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSL 57 Query: 81 KE-QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 E QQ+ VK IPHP Y+ SND+ML+KL + + + V+P+N+ Sbjct: 58 SPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS--A 115 Query: 140 GDVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G C V+GWG P + LQ + ++V ++CE D CAGD K R Sbjct: 116 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD-TMFCAGD-KAGRD 173 Query: 199 SFRGDSGGPLVCKKVAAGIVSYGQNDG---STPRAFTKVSTFLSWIKKTMKKS 248 S +GDSGGP+VC G+VS+G + P +T + F WI++T++ + Sbjct: 174 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3DFJ-A nrPDB Length = 263 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 75/247 (30%), Positives = 117/247 (47%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-----INVTL 75 I GG A P+ + Y G CGG L+ E +VL+AAHC S+ V L Sbjct: 1 ITGGSSAVAGQWPWQVSI----TYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH + + ++ + IIPHP+Y + DI LL+L S ++P++LP N Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANA 116 Query: 136 KVKPGDVCYVAGWGKLGPMGK--YSDTLQEVELTVQEDQKCESYL-------KNYFDKAN 186 G C V GWG + P LQ++E+ + + C + + +F + + Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQED 176 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSW 240 +CAG + + + +GDSGGPL C GIVS+G G + P +T S++ SW Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 241 IKKTMKK 247 I+ + + Sbjct: 237 IQSKVTE 243 >1EKB-B nrPDB Length = 235 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 71/238 (29%), Positives = 122/238 (51%), Gaps = 21/238 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS------GSKINVT 74 I+GG +++ + P++ L D + CG L+ D++++AAHC SK Sbjct: 1 IVGGSDSREGAWPWVVALYFDD----QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 75 LGAH---NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP 131 LG H N+ + ++ + +I+ +P YN + +NDI ++ L+ K + ++P+ LP Sbjct: 57 LGLHMASNLTSPQIETRL--IDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLP 114 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG 191 N PG +C +AGWG L G +D LQE ++ + ++KC+ + Y N +CAG Sbjct: 115 EENQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAG 174 Query: 192 DPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKK 243 S +GDSGGPL+C + + AG+ S+G + P + +V F WI+ Sbjct: 175 YEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQS 232 >3LC3-A nrPDB Length = 235 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 123/239 (51%), Gaps = 19/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS--KINVTLGAH 78 ++GG +AKP P+ L + CGG ++ E +++TAAHC + KI V G H Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDA----FCGGSIVNEKWIVTAAHCVETGVKITVVAGEH 56 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKT--ISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 NI+E E +Q V++IIPH YN+ ++DI LL+L +S V P+ + + Sbjct: 57 NIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYT 116 Query: 137 ---VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 +K G YV+GWG++ G+ + LQ + + + + C K + N CAG Sbjct: 117 NIFLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTK-FTIYNNMFCAGFH 174 Query: 194 KIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMK 246 + R S +GDSGGP V + GI+S+G+ +TKVS +++WIK+ K Sbjct: 175 EGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >3E0N-B nrPDB Length = 271 Score = 273 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 75/247 (30%), Positives = 116/247 (46%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-----INVTL 75 I GG A P+ + Y G CGG L+ E +VL+AAHC S+ V L Sbjct: 1 ITGGSSAVAGQWPWQVSI----TYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH + + ++ + IIPHP+Y + DI LL+L S ++P++LP Sbjct: 57 GAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQA 116 Query: 136 KVKPGDVCYVAGWGKLGPMGK--YSDTLQEVELTVQEDQKCESYL-------KNYFDKAN 186 G C V GWG + P LQ++E+ + + C S + +F + + Sbjct: 117 SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQED 176 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSW 240 +CAG + + + +GDSGGPL C GIVS+G G + P +T S++ SW Sbjct: 177 MVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 241 IKKTMKK 247 I+ + + Sbjct: 237 IQSKVTE 243 >4MPW-A nrPDB Length = 245 Score = 273 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 81/247 (32%), Positives = 127/247 (51%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG EA P+ L++ Y CGG LI +VLTAAHC G + L A + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPY-WMHFCGGSLIHPQWVLTAAHCVGPDVK-DLAALRV 58 Query: 81 KEQEK----MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + +E+ Q++PV +II HP + + I DI LL+L+ K SS V + LP + Sbjct: 59 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASET 118 Query: 137 VKPGDVCYVAGWGKLGPMGKYSD--TLQEVELTVQEDQKCESYLK--------NYFDKAN 186 PG C+V GWG + + L++V++ + E+ C++ + + Sbjct: 119 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 178 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSW 240 +CAG+ +R S +GDSGGPLVCK + AG+VS+G+ + P +T+V+ +L W Sbjct: 179 MLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 236 Query: 241 IKKTMKK 247 I + K Sbjct: 237 IHHYVPK 243 >1AO5-A nrPDB Length = 237 Score = 273 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 117/243 (48%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG + +S+P+ + E CGG L+ ++VLTAAHC + V LG + + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKE----HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 129 ++E Q V K PHP +N + S+D+MLL+L A + VKP+ Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + KPG C +GWG + P + D LQ V +T+ ++ C + Sbjct: 117 LPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-ML 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPRA---FTKVSTFLSWIKKTM 245 CAG+ + + R DSGGPL+C + G SYG P +T + F SWIK TM Sbjct: 174 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 233 Query: 246 KKS 248 K+ Sbjct: 234 MKN 236 >4GSO-A nrPDB Length = 232 Score = 273 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 73/233 (31%), Positives = 110/233 (47%), Gaps = 13/233 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG E + P++A+L YS CG LI +++V+TAAHC + + LG H+ Sbjct: 1 VLGGDECDINEHPFLAFL-----YSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSK 55 Query: 81 KEQEKMQQII-PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K + +Q P K I S+ + DIML+KL S + PL+LP V Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV-- 113 Query: 140 GDVCYVAGWGK-LGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWG P Y D + + + + C+ K +CAG + + Sbjct: 114 GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAK-TTLCAGVLEGGKD 172 Query: 199 SFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + GDSGGPL+C GIVSYG G P +T V + WI++ + + Sbjct: 173 TCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >6QHB-A nrPDB Length = 223 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 83/228 (36%), Positives = 116/228 (50%), Gaps = 11/228 (4%) Query: 22 IGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIK 81 + G S PY A L SG CGG LI +VLTAAHC + V LG HN+ Sbjct: 2 VHGGPCDKTSHPYQAALYT----SGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLG 57 Query: 82 EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGD 141 +QE Q+ VV+ + HP Y++ + DIMLL+L AK S ++P LP Sbjct: 58 QQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTT 115 Query: 142 VCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFR 201 C++ GWGK G + DT+Q + + ++CE N +CAGD K + S + Sbjct: 116 SCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAYPGQI-TQNMLCAGDEKYGKDSCQ 173 Query: 202 GDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPLVC G+VS+G P +T V + +WI+KT++ Sbjct: 174 GDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1TON-A nrPDB Length = 235 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 117/243 (48%), Gaps = 24/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG++ + +S+P+ + CGG LI +V+TAAHC + V LG +N+ Sbjct: 1 IVGGYKCEKNSQPWQVAV------INEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNL 54 Query: 81 KEQEKMQQIIPVVKIIPHPAYNS-----------KTISNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V + HP Y SND+MLL L A + VK ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + KV G C +GWG P S LQ V + + ++KC K+ + Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDV-ML 171 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 245 CAG+ + + + GDSGGPL+C V GI S G + P+ + K+ F SWIKK M Sbjct: 172 CAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVM 231 Query: 246 KKS 248 K++ Sbjct: 232 KEN 234 >2CGA-A nrPDB Length = 245 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 14/238 (5%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL-GA 77 I+ G EA P S P+ LQ + +G CGG LI E++V+TAAHC + +V + G Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGE 70 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + + Q + + K+ + YNS TI+NDI LLKL + A S V + LP + Sbjct: 71 FDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 130 Query: 138 KPGDVCYVAGWGKLG-PMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 G C GWG D LQ+ L + + C+ Y K ICAG Sbjct: 131 AAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKI-KDAMICAGAS--G 187 Query: 197 RASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 +S GDSGGPLVCK GIVS+G + STP + +V+ ++W+++T+ + Sbjct: 188 VSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 245 >1PYT-D nrPDB Length = 251 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 13/241 (5%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK--INVTL 75 + ++GG +A PHS P+ LQ + + + CGG LI + VLTAAHC + V L Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVAL 70 Query: 76 GAHNIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 G +N++ E E + V I H +NS + NDI L+KL + ++ LP Sbjct: 71 GKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEG 130 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES-YLKNYFDKANEICAGDP 193 + C+V GWG+L G + LQ+ V + C K +CAG Sbjct: 131 SLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCAGGD 190 Query: 194 KIKRASFRGDSGGPLVC----KKVAAGIVSYGQN----DGSTPRAFTKVSTFLSWIKKTM 245 + ++ GDSGGPL C + GIVS+G P FT+VS ++ WI + + Sbjct: 191 GV-ISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQKL 249 Query: 246 K 246 + Sbjct: 250 Q 250 >1FDP-A nrPDB Length = 235 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 88/238 (36%), Positives = 134/238 (56%), Gaps = 14/238 (5%) Query: 17 EAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKIN 72 G I+GG EA+ H+RPYMA +Q+ +G+ CGG L+ E +VL+AAHC + K+ Sbjct: 4 PRGRILGGREAEAHARPYMASVQL----NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQ 59 Query: 73 VTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 V LGAH++ + E +++ V++ +PHP TI +D++LL+L KA AV+PL R Sbjct: 60 VLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQR 119 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNYFDKANEICAG 191 + V PG +C VAGWG + G+ D+LQ V L V + C + +CA Sbjct: 120 VDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA- 178 Query: 192 DPKIKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 +R S +GDSGGPLVC V G+V+ G + P +T+V+++ +WI + Sbjct: 179 -ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >1P57-B nrPDB Length = 255 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 109/249 (43%), Gaps = 29/249 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG------SKINVT 74 I+GG + P+ L+ Y G+ CGG L+ D+VLTAAHC S+ V Sbjct: 1 IVGGRDTSLGRWPWQVSLR----YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNS------KTISNDIMLLKLKSKAKRSSAVKPL 128 GA +Q + V ++ H Y + SNDI L+ L S + ++P+ Sbjct: 57 AGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPV 114 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNYFDKANE 187 LP + G +C V GWG G+ + LQE + + + C + K Sbjct: 115 CLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKM 174 Query: 188 ICAGDPKIKRASFRGDSGGPLVC--------KKVAAGIVSYGQND--GSTPRAFTKVSTF 237 CAG P+ + +GDSGGP VC + GIVS+G P +TKVS F Sbjct: 175 FCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDF 234 Query: 238 LSWIKKTMK 246 WI + +K Sbjct: 235 REWIFQAIK 243 >1C5M-D nrPDB Length = 255 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 111/237 (46%), Gaps = 15/237 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAH 78 I+GG E K P+ A L CGG ++ E ++LTAAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALL---INEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN---V 135 N +++E + + V +I H + +T DI +L+LK+ V P LP R+ Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 117 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 + V+G+G+ G+ S L+ +E+ + C+ ++ N CAG Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCK-LSSSFIITQNMFCAGYDTK 176 Query: 196 KRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTP--RAFTKVSTFLSWIKKTMK 246 + + +GDSGGP V + GIVS+G+ +TKV+ FL WI ++MK Sbjct: 177 QEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >3S9B-A nrPDB Length = 234 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 69/232 (29%), Positives = 109/232 (46%), Gaps = 9/232 (3%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 ++GG E + P++ L S + C G LI ++VLTAAHC I + LG H+ Sbjct: 1 VVGGDECNINEHPFLVALY--TSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSK 58 Query: 81 KEQEKMQQI-IPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + + +QI +P K + DIML++L+ S+ + P++LP R+ V Sbjct: 59 NIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV-- 116 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 G C + GWGK+ Y D + + + + CE + +CAG K R + Sbjct: 117 GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDT 175 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDGS---TPRAFTKVSTFLSWIKKTMKKS 248 GDSGGPL+C GIV+ G P +TKV + +WI+ + + Sbjct: 176 CHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >2V35-A nrPDB Length = 240 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 14/241 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS--KINVTLGAH 78 ++GG EA+ +S P LQ S + CGG LIR+++V+TAAHC V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTI--SNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 N+ + + +Q + V KI+ HP +N+ + DI LL+L +S V+ LPR Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKI 195 + CY+ GWG G+ + TLQ+ L + C S K + +CAG + Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGV 180 Query: 196 KRASFRGDSGGPLVC----KKVAAGIVSY----GQNDGSTPRAFTKVSTFLSWIKKTMKK 247 R+ +GDSGGPL C + G+ S+ G N P FT+VS ++SWI + Sbjct: 181 -RSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIAS 239 Query: 248 S 248 + Sbjct: 240 N 240 >5ZFH-A nrPDB Length = 224 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 80/230 (34%), Positives = 114/230 (49%), Gaps = 13/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G++ K S P+ L CGG L+ + +VLTAAHC + V LG+ I Sbjct: 1 IIDGYKCKEGSHPWQVALL----KGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKI 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 +Q Q I K HP Y++KT NDIML++L K SS V+ + LP PG Sbjct: 57 GDQ--SAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPG 112 Query: 141 DVCYVAGWGKL-GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 C V+GWG P + L ++ + ++C+ K+ K +CAG P K + Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGK-TMLCAGIPDSKTNT 171 Query: 200 FRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPLVC G+VS+G + P +T+V + W+ +TMK Sbjct: 172 CNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >1LTO-A nrPDB Length = 245 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 78/247 (31%), Positives = 122/247 (49%), Gaps = 24/247 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 I+GG EA P+ L++ D Y CGG LI +VLTAAHC G + L + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRY-WMHFCGGSLIHPQWVLTAAHCLGPDVK-DLATLRV 58 Query: 81 KEQEK----MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + +E+ Q++PV +II HP + DI LL+L+ SS V + LP + Sbjct: 59 QLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASET 118 Query: 137 VKPGDVCYVAGWGKLGPMGKYSD--TLQEVELTVQEDQKCESYLK--------NYFDKAN 186 PG C+V GWG + L++V++ + E+ C++ + + Sbjct: 119 FPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDD 178 Query: 187 EICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSW 240 +CAG+ +R S +GDSGGPLVCK + AG+VS+ + + P +T+V+ +L W Sbjct: 179 MLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDW 236 Query: 241 IKKTMKK 247 I + K Sbjct: 237 IHHYVPK 243 >1SGF-A nrPDB Length = 240 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 119/238 (50%), Gaps = 23/238 (9%) Query: 26 EAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEK 85 + + +S+P+ + ++Y CGG L+ ++VLTAAHC K V LG +N E E Sbjct: 10 DCE-NSQPWHVAVYRFNKYQ----CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEP 64 Query: 86 MQQIIPVVKIIPHPAYNS-----------KTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 Q V K IPHP +N SND+MLL+L A + VKP+ LP Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEE 124 Query: 135 VKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP 193 K+ G C +GWG P+ KY D LQ V L + ++ C+ + A +CAG+ Sbjct: 125 PKL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDA-MLCAGEM 181 Query: 194 KIKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + DSGGPL+C + GI S+G + + P +TK+ F SWI++TM + Sbjct: 182 DGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >1FUJ-A nrPDB Length = 221 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 91/233 (39%), Positives = 130/233 (55%), Gaps = 19/233 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KINVTLG 76 I+GGHEA+PHSRPYMA LQ+ GS CGG LI FVLTAAHC +NV LG Sbjct: 1 IVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 AHN++ QE QQ V ++ Y+++ NDI+L++L S A S++V + LP+++ Sbjct: 60 AHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 V G C GWG++G + LQE+ +TV +F + + IC P+ K Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV----------TFFCRPHNICTFVPRRK 168 Query: 197 RASFRGDSGGPLVCKKVAAGI---VSYGQNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSGGPL+C + GI V +G P FT+V+ ++ WI+ T++ Sbjct: 169 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >3K65-B nrPDB Length = 308 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 77/277 (27%), Positives = 112/277 (40%), Gaps = 43/277 (15%) Query: 11 SLAPKTE--------AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLT 62 SL KTE G I+ G +A+ P+ L + CG LI + +VLT Sbjct: 32 SLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLT 89 Query: 63 AAHC----------SGSKINVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDI 110 AAHC + + + V +G H+ E+ ++I + KI HP YN + + DI Sbjct: 90 AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI 149 Query: 111 MLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKLGPMGK------YSDTL 161 L+KLK S + P+ LP R ++ G V GWG L L Sbjct: 150 ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL 209 Query: 162 QEVELTVQEDQKCESYLKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------K 212 Q V L + E C+ + N CAG + + GD+GGP V K Sbjct: 210 QVVNLPIVERPVCKDSTRIRI-TDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRW 268 Query: 213 VAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ +T V WI+K + + Sbjct: 269 YQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 305 >3NXP-A nrPDB Length = 424 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 43/277 (15%) Query: 11 SLAPKTE--------AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLT 62 SL KTE G I+ G +A+ P+ L + CG LI + +VLT Sbjct: 148 SLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLT 205 Query: 63 AAHC----------SGSKINVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDI 110 AAHC + + + V +G H+ E+ ++I + KI HP YN + + DI Sbjct: 206 AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI 265 Query: 111 MLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGWGKLGPMGK------YSDTL 161 L+KLK S + P+ LP R ++ G V GWG L L Sbjct: 266 ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL 325 Query: 162 QEVELTVQEDQKCESYLKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------K 212 Q V L + E C+ + N CAG + + GDSGGP V K Sbjct: 326 QVVNLPIVERPVCKDSTRIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRW 384 Query: 213 VAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ +T V WI+K + + Sbjct: 385 YQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 421 >5FCR-A nrPDB Length = 234 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 79/237 (33%), Positives = 126/237 (53%), Gaps = 15/237 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 I+GG EA H+RPYMA +Q+ +G+ CGG L+ E +VL+AAHC + V L Sbjct: 1 ILGGQEAAAHARPYMASVQV----NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 GAH++ E ++ V ++PHP ++ +D++L KL A V+PL L + Sbjct: 57 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDK 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE-SYLKNYFDKANEICAGDPK 194 +V+PG +C VAGWG + G+ D L ++ +++ C + N +CA Sbjct: 117 EVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ES 174 Query: 195 IKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 +R + RGDSG PLVC G+V++G +G P +T+VS++ WI+ + Sbjct: 175 NRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >4NZQ-A nrPDB Length = 557 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 73/262 (27%), Positives = 107/262 (40%), Gaps = 35/262 (13%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------S 67 G I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 296 DGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFT 353 Query: 68 GSKINVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAV 125 + + V +G H+ E+ ++I + KI HP YN + + DI L+KLK S + Sbjct: 354 ENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYI 413 Query: 126 KPLNLPRRNVK---VKPGDVCYVAGWGKLGPMGK------YSDTLQEVELTVQEDQKCES 176 P+ LP R ++ G V GWG L LQ V L + E C+ Sbjct: 414 HPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKD 473 Query: 177 YLKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------KVAAGIVSYGQNDGS- 226 + N CAG + + GDSGGP V K GIVS+G+ Sbjct: 474 STRIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 532 Query: 227 -TPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 533 GKYGFYTHVFRLKKWIQKVIDQ 554 >3P8G-A nrPDB Length = 241 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 110/242 (45%), Gaps = 22/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----------GSK 70 ++GG +A P+ L + + CG LI +++++AAHC ++ Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQ---GHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 71 INVTLGAHNIKEQE-KMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLN 129 LG H+ ++ Q + +II HP +N T DI LL+L+ A+ SS V+P+ Sbjct: 58 WTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPIC 117 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEIC 189 LP + G +V GWG G + LQ+ E+ V + CE+ L +C Sbjct: 118 LPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQI-TPRMMC 176 Query: 190 AGDPKIKRASFRGDSGGPLVC-----KKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIK 242 G S +GDSGGPL + AG+VS+G + P +T++ F WIK Sbjct: 177 VGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 236 Query: 243 KT 244 + Sbjct: 237 EN 238 >2AIQ-A nrPDB Length = 231 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 69/233 (29%), Positives = 106/233 (45%), Gaps = 14/233 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 +IGG E + ++A + Y+ CGG LI +++VLTA HC + + LG HN+ Sbjct: 1 VIGGDECNINEHRFLALV-----YANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNL 55 Query: 81 KEQEKMQ-QIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K K + P K N DIML++L + S+ + PL+LP V Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV-- 113 Query: 140 GDVCYVAGWGK-LGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWG P D + + + C++ K A +CAG + + Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG--LAATTLCAGILEGGKD 171 Query: 199 SFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + +GDSGGPL+C GI+S G P +TKV + WI+ + + Sbjct: 172 TCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >1MKW-K nrPDB Length = 308 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 74/261 (28%), Positives = 107/261 (40%), Gaps = 35/261 (13%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SG 68 G I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 48 GRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 69 SKINVTLGAHNIKEQE-KMQQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVK 126 + V +G H+ E K+++I + KI HP YN + + DI LLKLK + S + Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIH 165 Query: 127 PLNLPRRNVKVK---PGDVCYVAGWGKLGPMGKY------SDTLQEVELTVQEDQKCESY 177 P+ LP + K G V GWG LQ V L + E C++ Sbjct: 166 PVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAS 225 Query: 178 LKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------KVAAGIVSYGQNDGS-- 226 + N CAG + + GDSGGP V K GIVS+G+ Sbjct: 226 TRIRI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDG 284 Query: 227 TPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 285 KYGFYTHVFRLKKWIQKVIDR 305 >1ELT-A nrPDB Length = 236 Score = 263 bits (674), Expect = 3e-71, Method: Composition-based stats. Identities = 83/238 (34%), Positives = 118/238 (49%), Gaps = 15/238 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS--KINVTLGAH 78 ++GG A+P+S P+ LQ S CGG LIR+ +V+TAAHC S V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTI--SNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 N+ E +QI+ V + H +NS + DI LL+L ++A +SAV+ LP N Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKI 195 + + CY+ GWGK G SD+L++ L + C S K +CAG Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG--G 178 Query: 196 KRASFRGDSGGPLVCK----KVAAGIVSY----GQNDGSTPRAFTKVSTFLSWIKKTM 245 + GDSGGPL C+ G+ S+ G N P FT+VS ++SW+ M Sbjct: 179 ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >4E7N-A nrPDB Length = 238 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 72/235 (30%), Positives = 110/235 (46%), Gaps = 11/235 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + ++ L S + CGG LI +++VLTAAHC + LG H+ Sbjct: 1 IIGGDECNINEHRFLVALY--TSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSK 58 Query: 81 KEQEKMQQ-IIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K + +Q +P K + N DIML++L S K S + P + + Sbjct: 59 KVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPPSV 116 Query: 140 GDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESYLKNY--FDKANEICAGDPKIK 196 G VC + GWG++ P G Y D V + + E + C + + + +CAG + Sbjct: 117 GSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGG 176 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + + +GDSGGPL+C GI S+G P A+TKV L WI+ + + Sbjct: 177 KDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGN 231 >1BDA-A nrPDB Length = 265 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 79/252 (31%), Positives = 119/252 (47%), Gaps = 25/252 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSG--SKKCGGFLIREDFVLTAAHCSGSKI-----N 72 I GG A S P+ A + S CGG LI ++L+AAHC + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 73 VTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSK----AKRSSAVKPL 128 V LG + +Q V K I H ++ T NDI LL+LKS A+ SS V+ + Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKC-ESYLKNYFDKAN 186 LP ++++ C ++G+GK + YS+ L+E + + +C +L N N Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 187 EICAGDPKIKR------ASFRGDSGGPLVC----KKVAAGIVSYGQNDGST--PRAFTKV 234 +CAGD + + +GDSGGPLVC + GI+S+G G P +TKV Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKV 252 Query: 235 STFLSWIKKTMK 246 + +L WI+ M+ Sbjct: 253 TNYLDWIRDNMR 264 >1FIZ-A nrPDB Length = 263 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 118/251 (47%), Gaps = 23/251 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGS--KKCGGFLIREDFVLTAAHCSGSK-----INV 73 ++GG A+P + P+M LQI ++ CGG L+ +VLTAAHC +K + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 74 TLGAHNI-----KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 GA+ + K + Q V +II H Y S NDI L+K+ + P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 129 NLPR-RNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESY-LKNYFDKA 185 LP+ + + C+V GWG L G + S TLQE + + + + C S N ++ Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQND--GSTPRAFTKVSTF 237 +CAG P+ K + +GDSGGPL+C+ V GI S+G P +T + Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 238 LSWIKKTMKKS 248 L+WI + + Sbjct: 241 LNWIASKIGSN 251 >4Z6A-H nrPDB Length = 249 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 68/241 (28%), Positives = 106/241 (43%), Gaps = 19/241 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 I+GG P+ L + +G++ CGG LI +V++AAHC + L Sbjct: 1 IVGGKVCPKGECPWQVLLLV----NGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR-- 133 G H++ E + +Q V ++I Y T ++DI LL+L + V PL LP R Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 134 -NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 + V+GWG+L G + L + + Q CE+ CAG Sbjct: 117 SERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKI-TEYMFCAGY 175 Query: 193 PKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDGSTP--RAFTKVSTFLSWIKKTMK 246 + S +GDSGGP GIVS+GQ + +T+VS ++ W++K M+ Sbjct: 176 SDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMR 235 Query: 247 K 247 Sbjct: 236 S 236 >1ORF-A nrPDB Length = 234 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 97/235 (41%), Positives = 134/235 (57%), Gaps = 13/235 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-GSKINVTLGAHN 79 IIGG+E PHSRPYM L + + C G LI +D+VLTAAHC+ + V LGAH+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 56 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 I +E +QI+ V K P+P Y+ T D+ LL+L KAK + V L+LP++ VKP Sbjct: 57 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKP 116 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC---ESYLKNYFDKANEICAGDPKIK 196 G +C VAGWG+ +SDTL+EVE+T+ + + C Y N N +CAG + Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYG----QNDGSTPRAFTKVS-TFLSWIKKTMK 246 R S GDSG PL+C+ V G+ S+G D P + +S L+WI T+K Sbjct: 177 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1MZD-A nrPDB Length = 240 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 98/238 (41%), Positives = 134/238 (56%), Gaps = 17/238 (7%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVT 74 EIIGG E PHSRP+MA +Q Y G CGG LI +VLTAAHC G V Sbjct: 2 EIIGGKEVSPHSRPFMASIQ----YGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 57 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 LGAH++ + E +Q + + K IP S SNDIML+KL++ AK + VK L++ R Sbjct: 58 LGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSK 116 Query: 135 VKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCES---YLKNYFDKANEICA 190 ++ G C V GWG P + SDTL+EV +TV + C S Y + F + +CA Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 191 GDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDG--STPRAFTKVS-TFLSWIKKTM 245 GD K ++ S +GD+GGPL+CK V IVS G G + P +T ++ + +WIK + Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1FIW-A nrPDB Length = 290 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 77/248 (31%), Positives = 116/248 (46%), Gaps = 23/248 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGS--KKCGGFLIREDFVLTAAHCSG-----SKINV 73 IIGG +A + P+M LQI ++ CGG L+ ++LTAAHC + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 74 TLGAHNI-----KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 GA + K + Q V KII H Y++ + +NDI L+K+ + P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 129 NLPR-RNVKVKPGDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESY-LKNYFDKA 185 LP+ R + C+VAGWG L + S LQE + + + C S N ++ Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCKK------VAAGIVSYGQND--GSTPRAFTKVSTF 237 +CAG P+ K + +GDSGGPL+CK V GI S+G P +T ++ Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 238 LSWIKKTM 245 L+WI + Sbjct: 241 LNWIASKI 248 >2OQ5-A nrPDB Length = 232 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 69/236 (29%), Positives = 111/236 (47%), Gaps = 21/236 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS-----GSKINVTL 75 I+GG E + P+ A LQ + GS +CG LI ++++AAHC ++ + Sbjct: 1 IVGGTEVEEGEWPWQASLQ----WDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASF 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G + + + +II H Y + DI L +L S ++AV + LP + Sbjct: 57 GV----TIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY 112 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-ESYLKNYFDKANEICAGDPK 194 + +PGDV +V G+G L G + L++ ++T+ + C E N +CAG + Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLE 172 Query: 195 IKRASFRGDSGGPLVCK-----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKK 243 K + +GDSGGPLV AGIVS+G + P +T+V+ WI Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 228 >1VR1-H nrPDB Length = 261 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 73/261 (27%), Positives = 106/261 (40%), Gaps = 35/261 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSG--SKKCGGFLIREDFVLTAAHC----------SG 68 I+ G +A+ P+ L S CG LI + +VLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 SKINVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVK 126 + + V +G H+ E+ ++I + KI HP YN + + DI L+KLK S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 127 PLNLPRRNVK---VKPGDVCYVAGWGKLGPMGK------YSDTLQEVELTVQEDQKCESY 177 P+ LP R ++ G V GWG L LQ V L + E C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 178 LKNYFDKANEICA---GDPKIKRASFRGDSGGPLVCK------KVAAGIVSYGQNDGS-- 226 + N CA D + + GDSGGP V K GIVS+G+ Sbjct: 181 TRIRI-TDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 239 Query: 227 TPRAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQ 260 >1FON-A nrPDB Length = 240 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 113/242 (46%), Gaps = 18/242 (7%) Query: 23 GGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAHNI 80 G +A P+S + LQ + + CGG LI D+V+TA HC + V LG ++ Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 81 KEQEKMQQIIPVV--KIIPHPAYNSKTI--SNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 E +Q+IP+ + HP +NS + NDI L+KL A+ V+ NLP Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKI 195 + CY++GWG+L G D LQ+ L + + C + K +CAG Sbjct: 121 LPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT- 179 Query: 196 KRASFRGDSGGPLVC-----KKVAAGIVS----YGQNDGSTPRAFTKVSTFLSWIKKTMK 246 R+ GDSGGPL C G+ S +G N P FT+VS F+ WI +T+ Sbjct: 180 -RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIA 238 Query: 247 KS 248 + Sbjct: 239 SN 240 >1OP0-A nrPDB Length = 234 Score = 257 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 106/233 (45%), Gaps = 11/233 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 +IGG+E + ++ + CGG LI ++V+TAAHC + + LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFF----NTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSK 56 Query: 81 KEQEKMQQII-PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K + +Q P K I N++ + DIML+KL S + PL+ + Sbjct: 57 KVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPSV 114 Query: 140 GDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWG + P + D + + + C++ + +CAG + + Sbjct: 115 GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKD 174 Query: 199 SFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + GDSGGPL+C GIVSYG G P +T V + WI++ + + Sbjct: 175 TCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >1A5I-A nrPDB Length = 265 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 79/248 (31%), Positives = 118/248 (47%), Gaps = 25/248 (10%) Query: 23 GGHEAKPHSRPYMAYLQIMDEYSG--SKKCGGFLIREDFVLTAAHCS-----GSKINVTL 75 GG S P+ A + + S CGG LI +VLTAAHC ++ V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSK----AKRSSAVKPLNLP 131 G + + +Q V K I H ++ T +NDI LL+LKS A+ S +V+ + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCE-SYLKNYFDKANEIC 189 N+++ C ++G+GK YS+ L+E + + +C +L N N +C Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 190 AGDPKIKR------ASFRGDSGGPLVC----KKVAAGIVSYGQNDGST--PRAFTKVSTF 237 AGD + + +GDSGGPLVC GI+S+G G P +TKV+ + Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNY 255 Query: 238 LSWIKKTM 245 L WI+ M Sbjct: 256 LGWIRDNM 263 >2OCV-B nrPDB Length = 259 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 108/259 (41%), Gaps = 35/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + + Sbjct: 1 IVEGWDAEKGIAPWQVML--FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTEND 58 Query: 71 INVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPL 128 + V +G H+ E+ ++I + KI HP YN + + DI LLKLK S + P+ Sbjct: 59 LLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPV 118 Query: 129 NLPRRNVK---VKPGDVCYVAGWGKLGPMGKY------SDTLQEVELTVQEDQKCESYLK 179 LP + ++ G V GWG L LQ V L + E C++ + Sbjct: 119 CLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTR 178 Query: 180 NYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------KVAAGIVSYGQND--GSTP 228 N CAG + + GDSGGP V K GIVS+G+ Sbjct: 179 IRI-TDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKY 237 Query: 229 RAFTKVSTFLSWIKKTMKK 247 +T V +WI+K + + Sbjct: 238 GFYTHVFRLKAWIQKVIDQ 256 >1YC0-A nrPDB Length = 283 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 118/245 (48%), Gaps = 23/245 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVT 74 IIGG + P S P++A + I G C G L+ +V++AAHC ++V Sbjct: 35 RIIGGSSSLPGSHPWLAAIYI-----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVV 89 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSK----AKRSSAVKPLN 129 LG H + Q + K IP+ Y+ +D++L++LK K A RS V+P+ Sbjct: 90 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 149 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCES-YLKNYFDKANE 187 LP G C +AGWG L YS +L+E + + D KC S + N Sbjct: 150 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 209 Query: 188 ICAGDPKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDGS--TPRAFTKVSTFLSWI 241 +CAG K + +GDSGGPL C+K GI+S+G G P +T+V+ ++ WI Sbjct: 210 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 269 Query: 242 KKTMK 246 ++ Sbjct: 270 NDRIR 274 >1GVZ-A nrPDB Length = 237 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 83/243 (34%), Positives = 119/243 (48%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + HS+P+ + + G +CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPWQVAVY----HQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYN-----------SKTISNDIMLLKLKSKAKRSSAVKPLN 129 + E Q V P ++ IS+D+MLL+L A+ + AVK L+ Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 130 LPRRNVKVKPGDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 188 LP + K+ G CY +GWG + + S TLQ VEL +Q ++KC + Sbjct: 117 LPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKM-TEFVL 173 Query: 189 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTM 245 CA + GDSGG L+C V GI S+G D + FTKV WIK+T+ Sbjct: 174 CATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETI 233 Query: 246 KKS 248 +K+ Sbjct: 234 EKN 236 >1ETT-H nrPDB Length = 259 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 73/259 (28%), Positives = 106/259 (40%), Gaps = 35/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 71 INVTLGAHNIKEQE-KMQQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPL 128 + V +G H+ E K+++I + KI HP YN + + DI LLKLK + S + P+ Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 129 NLPRRNVKVK---PGDVCYVAGWGKLGPMGKY------SDTLQEVELTVQEDQKCESYLK 179 LP + K G V GWG LQ V L + E C++ + Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR 178 Query: 180 NYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------KVAAGIVSYGQNDGS--TP 228 N CAG + + GDSGGP V K GIVS+G+ Sbjct: 179 IRI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKY 237 Query: 229 RAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 238 GFYTHVFRLKKWIQKVIDR 256 >2BDH-A nrPDB Length = 223 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 72/230 (31%), Positives = 120/230 (52%), Gaps = 12/230 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G + PHS+P+ A L + +E C G L+ +VL+AAHC + + LG H++ Sbjct: 1 IINGEDCSPHSQPWQAALVMENEL----FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 56 Query: 81 K-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + +QE Q++ + HP YN ++ND+ML+KL S ++ +++ + Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--PTA 114 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 G+ C V+GWG L G+ LQ V ++V ++ C + + CAG + ++ S Sbjct: 115 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLY-HPSMFCAGGGQDQKDS 172 Query: 200 FRGDSGGPLVCKKVAAGIVSYGQNDGST---PRAFTKVSTFLSWIKKTMK 246 GDSGGPL+C G+VS+G+ P +T + F WI+KT++ Sbjct: 173 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1SC8-U nrPDB Length = 262 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 20/248 (8%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSG-SKKCGGFLIREDFVLTAAHCS-----GSKINV 73 +IIGG ++P+ A + + CGG LI +V++A HC V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTIS--NDIMLLKLKSK----AKRSSAVKP 127 LG + + + V +I H Y++ T++ NDI LLK++SK A+ S ++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 128 LNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCES-YLKNYFDKA 185 ++LP + G C + G+GK Y + L+ + + ++C+ + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 194 Query: 186 NEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDG--STPRAFTKVSTFLS 239 +CA DP+ K S +GDSGGPLVC + GIVS+G+ P +T+VS FL Sbjct: 195 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLP 254 Query: 240 WIKKTMKK 247 WI+ K+ Sbjct: 255 WIRSHTKE 262 >5LHN-A nrPDB Length = 247 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 70/246 (28%), Positives = 113/246 (45%), Gaps = 21/246 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDE--YSGSKKCGGFLIREDFVLTAAHCS-----GSKINV 73 I+GG + ++P+ A + ++ S KCGG LI +V +AAHC V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT--ISNDIMLLKLKSK----AKRSSAVKP 127 LG + V ++I H Y + NDI LLK+++ A+ S +++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 128 LNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKC-ESYLKNYFDKA 185 + LP R G C + G+GK Y L+ + + ++C + + Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 186 NEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLS 239 +CA DP+ K S +GDSGGPL+C +GIVS+G+ + P +T+VS FL Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLD 240 Query: 240 WIKKTM 245 WI+ + Sbjct: 241 WIQSHI 246 >2R0L-A nrPDB Length = 248 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 78/244 (31%), Positives = 118/244 (48%), Gaps = 23/244 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 IIGG + P S P++A + I G C G L+ +V++AAHC ++V L Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-----GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSK----AKRSSAVKPLNL 130 G H + Q + K IP+ Y+ +D++L++LK K A RS V+P+ L Sbjct: 56 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 115 Query: 131 PRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCES-YLKNYFDKANEI 188 P G C +AGWG L YS +L+E + + D KC S + N + Sbjct: 116 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 175 Query: 189 CAGDPKIKRASFRGDSGGPLVCKK----VAAGIVSYGQNDGS--TPRAFTKVSTFLSWIK 242 CAG K + +GDSGGPL C+K GI+S+G G P +T+V+ ++ WI Sbjct: 176 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 235 Query: 243 KTMK 246 ++ Sbjct: 236 DRIR 239 >3S69-A nrPDB Length = 234 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 69/233 (29%), Positives = 106/233 (45%), Gaps = 11/233 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 +IGG E + + S C G LI E++VLTAAHC + + LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFF----NSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSK 56 Query: 81 KEQEKMQQII-PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K + +Q P K I N + + DIML+KL S+ S + + L + Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPPSV 114 Query: 140 GDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC++ GWG + P Y D + + +D C++ + +CAG + + Sbjct: 115 GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKD 174 Query: 199 SFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + GDSGGPL+C GIVS+G G P +TKV + WI+ + + Sbjct: 175 TCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >1BQY-A nrPDB Length = 234 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 100/233 (42%), Gaps = 11/233 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 + GG E + + L S CGG LI +D+V+TAAHC + + G H+ Sbjct: 1 VFGGDECNINEHRSLVVLF----NSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSK 56 Query: 81 KEQEKMQQII-PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 K + +Q P K + DIML+KL S S + PL+ + Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPSV 114 Query: 140 GDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 G VC + GWGK P + Y D + + + C + +CAG + R Sbjct: 115 GSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRD 174 Query: 199 SFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + DSGGPL+C + GIVS+G P +TKV +L WIK + + Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >3F6U-H nrPDB Length = 240 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 21/242 (8%) Query: 22 IGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKINVTLGAHN 79 I G + P+ L + CG LI +VLTAAHC K+ V LG ++ Sbjct: 2 IDGKMTRRGDSPWQVVL---LDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD 58 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK--- 136 ++ EK + + + ++ HP Y+ T NDI LL L A S + P+ LP + Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 137 -VKPGDVCYVAGWGKLGPMGKYSD-----TLQEVELTVQEDQKCESYLKNYFDKANEICA 190 + G V GWG K + L +++ V +C + N N +CA Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMV-SENMLCA 177 Query: 191 GDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKT 244 G ++ + GDSGGP+V G+VS+G+ G +TKVS +L WI Sbjct: 178 GILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGH 237 Query: 245 MK 246 ++ Sbjct: 238 IR 239 >4XDE-A nrPDB Length = 257 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 114/244 (46%), Gaps = 26/244 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKINVTL 75 ++GG A + PY+A L Y G C G LI +VLTAAHC + + V L Sbjct: 3 VVGGLVALRGAHPYIAAL-----YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK-----RSSAVKPLNL 130 G + Q + V H A++ + +D+ LL+L+ A S V+P++L Sbjct: 58 GQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSL 117 Query: 131 PRRNVKVKPGDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCES-YLKNYFDKANEI 188 P + +C VAGWG +Y+ LQE ++ ++C + + + Sbjct: 118 PSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGML 177 Query: 189 CAGDPKIKRASFRGDSGGPLVCKK-------VAAGIVSYGQNDG--STPRAFTKVSTFLS 239 CAG + + +GDSGGPLVC+ GI+S+G G + P +T V+ +L+ Sbjct: 178 CAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLA 237 Query: 240 WIKK 243 WI++ Sbjct: 238 WIRE 241 >4Q7Y-A nrPDB Length = 250 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 89/237 (37%), Positives = 121/237 (51%), Gaps = 14/237 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG----SKINVTLG 76 IIGGHE PHSRPYMA ++ + G CGGFL+R +V++AAHC V LG Sbjct: 1 IIGGHEVTPHSRPYMASVR----FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP-RRNV 135 AH + E QQ+ + + HP Y+ T +NDI LL+L A AV L LP RR Sbjct: 57 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRAR 116 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICA-GDPK 194 G C VAGWG + + L E ++ V + C S K + +C Sbjct: 117 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 175 Query: 195 IKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 +R DSGGPLVC+ A G+VS+ D TP +T+VS F++WI +++S Sbjct: 176 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 232 >5TO3-B nrPDB Length = 409 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 104/259 (40%), Gaps = 35/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + + Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 71 INVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPL 128 + V +G H+ E+ ++I + KI HP YN + + DI L+KLK S + P+ Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 129 NLPRRNVK---VKPGDVCYVAGWGKLGPMGK------YSDTLQEVELTVQEDQKCESYLK 179 LP R ++ G V GWG L LQ V L + E C+ + Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTR 178 Query: 180 NYFDKANEICAGD---PKIKRASFRGDSGGPLVCK------KVAAGIVSYGQNDGS--TP 228 N CAG + + GDSGGP V K GIVS G Sbjct: 179 IRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKY 237 Query: 229 RAFTKVSTFLSWIKKTMKK 247 +T V WI+K + + Sbjct: 238 GFYTHVFRLKKWIQKVIDQ 256 >2OLG-A nrPDB Length = 278 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 71/271 (26%), Positives = 123/271 (45%), Gaps = 33/271 (12%) Query: 7 LLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKK-CGGFLIREDFVLTAAH 65 LL + EA +I+ G + P P+ A + + + + CGG LI +++TAAH Sbjct: 9 LLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAH 68 Query: 66 CSGSKI--------NVTLGAHNIKEQEKMQQIIPV-----------VKIIPHPAYNSKTI 106 C ++ V LG N + V + I HP Y + Sbjct: 69 CVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSK 128 Query: 107 S--NDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEV 164 +DI L++L + + ++ ++P+ LP+ N +V+ G V GWG+ G+YS Q++ Sbjct: 129 DRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKL 187 Query: 165 ELTVQEDQKCESYLK--NYFDKANEICAGDPKIKRASFRGDSGGPL-----VCKKVAAGI 217 + V ++C +++++CAG K + S GDSGGPL + G+ Sbjct: 188 AVPVVHAEQCAKTFGAAGVRVRSSQLCAGGEKA-KDSCGGDSGGPLLAERANQQFFLEGL 246 Query: 218 VSYGQNDGST--PRAFTKVSTFLSWIKKTMK 246 VS+G G+ P +TKV + WI+ ++ Sbjct: 247 VSFGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >2ZKS-A nrPDB Length = 240 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 87/238 (36%), Positives = 122/238 (51%), Gaps = 17/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG---SKINVTLGA 77 IIGG E PHSRPYMA LQ +GS CGG L+ +VLTAAHC +++ + LG Sbjct: 1 IIGGREVIPHSRPYMASLQ----RNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 H + + I HP Y + ND+ LL+L K K S ++PL LP + Sbjct: 57 HTLDSP---GLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQV 113 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-ESYLKNYFDKANEICAGDPKI 195 V G C +AGWG G+ S L+E++L V + + C S N + +C Sbjct: 114 VAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 173 Query: 196 KRASFRGDSGGPLVCKK--VAAGIVSYGQNDGS---TPRAFTKVSTFLSWIKKTMKKS 248 +A +GDSGGPLVC K V AG++S+ + P T V+ ++SWI+K +S Sbjct: 174 DQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >5LPF-A nrPDB Length = 234 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 70/237 (29%), Positives = 109/237 (45%), Gaps = 21/237 (8%) Query: 24 GHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQ 83 G S+P+ L S C G L+ + +VLTAAHC + +G ++ Sbjct: 7 GSPCARGSQPWQVSLF----NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLL 62 Query: 84 EKMQQIIPVVKIIPHPAYNS--------KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 + +Q+ + + HP Y+ +T +D+MLLKL V+ L LP R Sbjct: 63 QG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRC- 120 Query: 136 KVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 +PGD C VAGWG KY+ L +T+ ++CE + N ICAG Sbjct: 121 -AQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPG-VVTNNMICAG-LD 177 Query: 195 IKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 + + DSGGPLVC + GI+S+G P +T++ ++SWI K ++ + Sbjct: 178 RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >4IW4-E nrPDB Length = 279 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 73/267 (27%), Positives = 117/267 (43%), Gaps = 43/267 (16%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEY---SGSKKCGGFLIREDFVLTAAHCSGSK------- 70 IIGG A+P P+ A + + D + G L+ ++LTAAH S+ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 71 ------INVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + V LG H+++++ +++ HP +N + ++DI L++L+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSG-AVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 125 VKPLNLPRRNVK-VKPGDVCYVAGWGKLGPM-----------GKYSDTLQEVELTVQEDQ 172 V P+ LPR + P + VAGWG P SD LQ V+L V Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 173 KCESYL----KNYFDKANEICAGDPKIKRASFRGDSGGPLV------CKKVAAGIVSYG- 221 +C++ NY N CAG + + + GDSGG V + V G+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 222 -QNDGST--PRAFTKVSTFLSWIKKTM 245 + GS +TKVS ++ W+ + M Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >4KKD-A nrPDB Length = 433 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 72/270 (26%), Positives = 116/270 (42%), Gaps = 43/270 (15%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEY---SGSKKCGGFLIREDFVLTAAHCSGSK---- 70 IIGG A+P P+ A + + D + G L+ ++LTAAH S+ Sbjct: 152 VQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDT 211 Query: 71 ---------INVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKR 121 + V LG H+++++ +++ HP +N + ++DI L++L+ Sbjct: 212 TVIPVSKEHVTVYLGLHDVRDKSG-AVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPL 270 Query: 122 SSAVKPLNLPRRNVK-VKPGDVCYVAGWGKLGPM-----------GKYSDTLQEVELTVQ 169 V P+ LPR + P + VAGWG P SD LQ V+L V Sbjct: 271 GPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVV 330 Query: 170 EDQKCESYL----KNYFDKANEICAGDPKIKRASFRGDSGGPLV------CKKVAAGIVS 219 +C++ NY N CAG + + + GDSG V + V G+VS Sbjct: 331 PHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVS 390 Query: 220 YG--QNDGST--PRAFTKVSTFLSWIKKTM 245 +G + GS +TKVS ++ W+ + M Sbjct: 391 WGGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >1AZZ-A nrPDB Length = 226 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 83/228 (36%), Positives = 115/228 (50%), Gaps = 15/228 (6%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK--INVTLGAH 78 I+GG EA P+S P+ A L I D Y CGG LI +++LTAAHC ++V LGAH Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMY----FCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 79 NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVK 138 NI+E E Q I H YNS ISNDI +++L ++A+ + LP +V V Sbjct: 57 NIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV- 115 Query: 139 PGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKR 197 G V GWG SD L++V++ + + C++ IC D + Sbjct: 116 -GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG--IVTDGNICI-DSTGGK 171 Query: 198 ASFRGDSGGPLVCKKVAAGIVSYG--QND-GSTPRAFTKVSTFLSWIK 242 + GDSGGPL + GI S+G P AFT+V+ FL WI+ Sbjct: 172 GTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >1Q3X-A nrPDB Length = 328 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 111/258 (43%), Gaps = 32/258 (12%) Query: 11 SLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS--- 67 L+ +T G I GG +AKP P+ + G G L+ +++VLTAAH Sbjct: 77 GLSARTTGGRIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQ 130 Query: 68 ---GSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSS 123 S +++ +G Q + H Y NDI L+KL +K +S Sbjct: 131 KHDASALDIRMGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKLNNKVVINS 188 Query: 124 AVKPLNLPRRNVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-----ES 176 + P+ LPR+ + ++ D+ +GWG G + L V++ + + QKC + Sbjct: 189 NITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKP 247 Query: 177 YLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYG---QNDGST 227 AN +CAG + S RGDSGG LV + GIVS+G + Sbjct: 248 PYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQ 307 Query: 228 PRAFTKVSTFLSWIKKTM 245 +TKV ++ WI+ + Sbjct: 308 YGVYTKVINYIPWIENII 325 >1GPZ-A nrPDB Length = 399 Score = 236 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 78/265 (29%), Positives = 125/265 (47%), Gaps = 31/265 (11%) Query: 5 LLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA 64 L + + P + +IIGG +AK + P+ + I GG L+ + ++LTAA Sbjct: 142 LPVCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAA 195 Query: 65 HC---------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSK---TISNDIML 112 H S + ++V LG N++E K+ P+ ++ HP Y DI L Sbjct: 196 HTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIAL 254 Query: 113 LKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQ 172 L+L++ + P+ LP + G + YV+G+G + K + L+ V L V Q Sbjct: 255 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQ 312 Query: 173 KCESYLKNY----FDKANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQ 222 CE++L+ N CAG P +K+ + +GDSGG P + VA GIVS+G Sbjct: 313 ACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI 372 Query: 223 NDGSTPRAFTKVSTFLSWIKKTMKK 247 +TKV ++ WIKK M++ Sbjct: 373 GCSRGYGFYTKVLNYVDWIKKEMEE 397 >5XRF-A nrPDB Length = 242 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 61/237 (25%), Positives = 103/237 (43%), Gaps = 9/237 (3%) Query: 15 KTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVT 74 + + +IGG+E + ++A + +C G LI E++VL AAHC +N+ Sbjct: 1 QKSSELVIGGNECDTNEHRFLAA--FFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIY 58 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HN Q +Q ++ + T D++LLKL S+ + PL+ Sbjct: 59 LGMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LP 116 Query: 134 NVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 + G VC V GWG + D + + +C ++ + + +CAG Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 193 PKIKRASFRGDSGGPLVCKKVAAGIVSYG---QNDGSTPRAFTKVSTFLSWIKKTMK 246 + + DSGGPL+C GIV +G + P +T+VS + WI+ + Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIA 233 >2XXL-A nrPDB Length = 408 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 76/263 (28%), Positives = 112/263 (42%), Gaps = 35/263 (13%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----GSKINV 73 + + G+E K SRP+MA L+ CGG +I E ++LTAAHC + Sbjct: 116 SQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEI 175 Query: 74 TLGAHNIKEQEKMQQI------------IPVVKIIPHPAYNSKTISNDIMLLKLKSKAKR 121 LG H I +E +Q + + K + H Y+++ I +DI LLKL Sbjct: 176 RLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235 Query: 122 SSAVKPLNLP---RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL 178 +KP+ LP K + +V GWG G SD L + + +Q C Sbjct: 236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSACSQAY 294 Query: 179 KNYFDKANEICAGDPKIKRASFRGDSGGPLVC----------KKVAAGIVSYG---QNDG 225 + +++C G ++ S +GDSGGPL K V GIVS G Sbjct: 295 R-RAVPLSQLCVGGGDLQ-DSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQI 352 Query: 226 STPRAFTKVSTFLSWIKKTMKKS 248 S P +T V ++ WI TM + Sbjct: 353 SLPGLYTNVGEYVQWITDTMASN 375 >4IGD-A nrPDB Length = 406 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 64/254 (25%), Positives = 112/254 (44%), Gaps = 34/254 (13%) Query: 19 GEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC------------ 66 +I G A+ + P++A L +G CGG L+ +++TAAHC Sbjct: 154 AQIFNGRPAQKGTTPWIAML---SHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTL 210 Query: 67 ------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 S S + LG H ++ +Q + V HP Y+ T ND+ L++L Sbjct: 211 RDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPV 270 Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN 180 ++ V P+ LP + G + V+GWGK + ++ +TL E+E+ + + C+ Sbjct: 271 LNAFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAP 327 Query: 181 --YFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQNDGST--PRA 230 + ICAG+ + + + GDSGGP+V + G VS+G + G Sbjct: 328 LKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGV 387 Query: 231 FTKVSTFLSWIKKT 244 ++ + WI++ Sbjct: 388 YSYIHHNKDWIQRV 401 >1ELV-A nrPDB Length = 333 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 72/264 (27%), Positives = 116/264 (43%), Gaps = 39/264 (14%) Query: 13 APKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI- 71 P E IIGG +A + P+ + + GG LI E +VLTAAH Sbjct: 75 EPFEEKQRIIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNRE 127 Query: 72 -NVTLGAHNIKEQE--KMQQIIPVVKIIPHPAYN-------SKTISNDIMLLKLKSKAKR 121 + +G+ +++ K + + P + HP + NDI L++LK K Sbjct: 128 PTMYVGSTSVQTSRLAKSKMLTP-EHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKM 186 Query: 122 SSAVKPLNLP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE---- 175 V P+ LP + + GD+ ++GWG+ + + L+ L V +KC+ Sbjct: 187 GPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKV 245 Query: 176 ----SYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKK-------VAAGIVSYGQND 224 + + Y N ICAG K S +GDSGG + AAG+VS+G Sbjct: 246 EKPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC 304 Query: 225 GSTPRAFTKVSTFLSWIKKTMKKS 248 G+ +T+V ++ WI KTM+++ Sbjct: 305 GTY-GLYTRVKNYVDWIMKTMQEN 327 >1MD7-A nrPDB Length = 328 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 77/264 (29%), Positives = 123/264 (46%), Gaps = 31/264 (11%) Query: 5 LLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA 64 L + + P + IIGG +AK + P+ + I GG L+ + ++LTAA Sbjct: 74 LPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAA 127 Query: 65 HC---------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSK---TISNDIML 112 H S + ++V LG N++E K+ P+ ++ HP Y DI L Sbjct: 128 HTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIAL 186 Query: 113 LKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQ 172 L+L++ + P+ LP + G + YV+G+G + K + L+ V L V Q Sbjct: 187 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQ 244 Query: 173 KCESYLKNY----FDKANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQ 222 CE++L+ N CAG P +K+ + +GD+GG P + VA GIVS+G Sbjct: 245 ACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI 304 Query: 223 NDGSTPRAFTKVSTFLSWIKKTMK 246 +TKV ++ WIKK M+ Sbjct: 305 GCSRGYGFYTKVLNYVDWIKKEME 328 >1ZJK-A nrPDB Length = 403 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 112/258 (43%), Gaps = 32/258 (12%) Query: 11 SLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS--- 67 L+ +T G+I GG +AKP P+ + G G L+ +++VLTAAH Sbjct: 152 GLSARTTGGQIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQ 205 Query: 68 ---GSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSS 123 S +++ +G Q + H Y NDI L+KL +K +S Sbjct: 206 KHDASALDIRMGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKLNNKVVINS 263 Query: 124 AVKPLNLPRRNVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-----ES 176 + P+ LPR+ + ++ D+ +GWG G + L V++ + + QKC + Sbjct: 264 NITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKP 322 Query: 177 YLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYG---QNDGST 227 AN +CAG + S RGDSGG LV + GIVS+G + Sbjct: 323 PYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQ 382 Query: 228 PRAFTKVSTFLSWIKKTM 245 +TKV ++ WI+ + Sbjct: 383 YGVYTKVINYIPWIENII 400 >4BXW-A nrPDB Length = 423 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 106/248 (42%), Gaps = 25/248 (10%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK--INVTLGA 77 I+ G + K P+ A L E CGG ++ +VLTAAHC I+V +G Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKE---GVFCGGTILSPIYVLTAAHCINETETISVVVGE 225 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNS---------KTISNDIMLLKLKSKAKRSSAVKPL 128 + E ++ V KI H + DI ++++K+ + S V P Sbjct: 226 IDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPA 284 Query: 129 NLPRRNVK---VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKA 185 LP + + D V+G+G++ G S TL+ +++ + C + Sbjct: 285 CLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPI-TP 343 Query: 186 NEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDGS--TPRAFTKVSTFLS 239 N CAG + R + +GDSGGP GIVS G+ +TK+S F+ Sbjct: 344 NMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIP 403 Query: 240 WIKKTMKK 247 WIK+ M++ Sbjct: 404 WIKRIMRQ 411 >4DJZ-B nrPDB Length = 251 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 34/252 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-------------- 66 I G A+ + P++A L +G CGG L+ +++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAML---SHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 67 ----SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRS 122 S S + LG H ++ +Q + V HP Y+ T ND+ L++L + Sbjct: 58 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 117 Query: 123 SAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN-- 180 + V P+ LP + G + V+GWGK + ++ +TL E+E+ + + C+ Sbjct: 118 AFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAPLK 174 Query: 181 YFDKANEICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYGQNDGST--PRAFT 232 + ICAG+ + + + GDSGGP+V + G VS+G + G ++ Sbjct: 175 KKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYS 234 Query: 233 KVSTFLSWIKKT 244 + WI++ Sbjct: 235 YIHHNKDWIQRV 246 >1EQ9-A nrPDB Length = 222 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 113/233 (48%), Gaps = 17/233 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG-----SKINVTL 75 I+GG +A PY L++ SGS +CG ++ + VLTAAHC +++ V + Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 76 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 135 G + + E + V + + Y+ + ND+ L+ L + K + V+P+ L + Sbjct: 57 GTNYLSESGD---VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDE 113 Query: 136 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 ++ C + GWG G + LQE+EL V ++CE D + IC K Sbjct: 114 DLESN-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVID--SHICT-LTKR 169 Query: 196 KRASFRGDSGGPLVCKKVAAGIVSYGQNDG-STPRAFTKVSTFLSWIKKTMKK 247 + GDSGGPLV GIVS+G P +T+VS+F+SWI +KK Sbjct: 170 GEGACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >1YM0-A nrPDB Length = 238 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 108/242 (44%), Gaps = 18/242 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKINVTLG 76 I+GG EA+P+ P+ + + S S CGG +I + +V+ AAHC + + +++ +G Sbjct: 1 IVGGIEARPYEFPWQVS--VRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR-RNV 135 H+ ++Q V I + Y+ T+ ND+ ++K V P+ P N Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 136 KVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 V C +GWG + G L+ V L + + C++ + + ICA D Sbjct: 119 YVYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNT 176 Query: 195 I--KRASFRGDSGGPLVCKK-----VAAGIVSYGQNDG-STPRAFTKVSTFLSWIKKTMK 246 R S +GDSGGPL K GIVS+G P +++V WI T+ Sbjct: 177 GMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTIT 236 Query: 247 KS 248 + Sbjct: 237 NN 238 >2QY0-B nrPDB Length = 242 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 76/249 (30%), Positives = 119/249 (47%), Gaps = 31/249 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC---------SGSKI 71 IIGG +AK + P+ + I GG L+ + ++LTAAH S + + Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 72 NVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSK---TISNDIMLLKLKSKAKRSSAVKPL 128 +V LG N++E K+ P+ ++ HP Y DI LL+L++ + P+ Sbjct: 55 DVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 113 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNY----FDK 184 LP + G + YV+G+G + K + L+ V L V Q CE++L+ Sbjct: 114 CLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFS 171 Query: 185 ANEICAGDPKIKRASFRGDSGG------PLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFL 238 N CAG P +K+ + +GDSGG P + VA GIVS+G +TKV ++ Sbjct: 172 QNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYV 231 Query: 239 SWIKKTMKK 247 WIKK M++ Sbjct: 232 DWIKKEMEE 240 >5UBM-A nrPDB Length = 252 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 114/257 (44%), Gaps = 39/257 (15%) Query: 20 EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI--NVTLGA 77 IIGG +A + P+ + + GG LI E +VLTAAH + +G+ Sbjct: 1 RIIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNREPTMYVGS 53 Query: 78 HNIKEQE--KMQQIIPVVKIIPHPAYN-------SKTISNDIMLLKLKSKAKRSSAVKPL 128 +++ K + + P + HP + NDI L++LK K V P+ Sbjct: 54 TSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 112 Query: 129 NLP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE--------SYL 178 LP + + GD+ ++GWG+ + + L+ L V +KC+ + Sbjct: 113 CLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 179 KNYFDKANEICAGDPKIKRASFRGDSGGPLVCKK-------VAAGIVSYGQNDGSTPRAF 231 + Y N ICAG K S +GDSGG + AAG+VS+G G+ + Sbjct: 172 EAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY-GLY 229 Query: 232 TKVSTFLSWIKKTMKKS 248 T+V ++ WI KTM+++ Sbjct: 230 TRVKNYVDWIMKTMQEN 246 >1AE5-A nrPDB Length = 225 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 18/232 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK----INVTLG 76 I+GG +A+P P++A +Q G CGG LI FV+TAA C S+ V LG Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 A++++ +E+ + + + Y+ + ND+MLL+L +A +S+V L LP +N Sbjct: 57 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 V+ G C VAGWG G+ S + V +TV + +C + N +C G + Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC---------RPNNVCTGVLTRR 167 Query: 197 RASFRGDSGGPLVCKKVAAGIVSYGQN-DGSTPRAFTKVSTFLSWIKKTMKK 247 GD G PLVC+ +A G+ S+ G P FT+V+ F WI + Sbjct: 168 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 219 >2XRC-A nrPDB Length = 565 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 74/257 (28%), Positives = 110/257 (42%), Gaps = 33/257 (12%) Query: 11 SLAPKTEAG----------EIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFV 60 SL PK G I+GG A+ P+ + + + CGG I ++ Sbjct: 302 SLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI----KDASGITCGGIYIGGCWI 357 Query: 61 LTAAHCSGS----KINVTLGA-HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKL 115 LTAAHC + + + I K I V +II H YN+ T NDI L+++ Sbjct: 358 LTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM 417 Query: 116 KSKAKRSSAVKP----LNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQED 171 K + P +P +P D C V+GWG+ + +LQ E+ + + Sbjct: 418 KKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN 476 Query: 172 QKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKK-----VAAGIVSYGQNDGS 226 C + N F + CAG + +GDSGGPLVC G+VS+G+N G Sbjct: 477 --CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGK 534 Query: 227 T--PRAFTKVSTFLSWI 241 P +TKV+ + WI Sbjct: 535 PEFPGVYTKVANYFDWI 551 >4FXG-H nrPDB Length = 242 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 106/248 (42%), Gaps = 32/248 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS------GSKINVT 74 I GG +AKP P+ + G G L+ +++VLTAAH S +++ Sbjct: 1 IYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 54 Query: 75 LGAHNIKEQEKMQQIIPVVKIIPHPAYNSKT-ISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 +G Q + H Y NDI L+KL +K +S + P+ LPR+ Sbjct: 55 MGTLKRLSPHYTQAWSEA--VFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRK 112 Query: 134 NVK--VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKC-----ESYLKNYFDKAN 186 + ++ D+ +GWG G + L V++ + + QKC + AN Sbjct: 113 EAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTAN 171 Query: 187 EICAGDPKIKRASFRGDSGGPLVC------KKVAAGIVSYG---QNDGSTPRAFTKVSTF 237 +CAG + S RGD+GG LV + GIVS+G + +TKV + Sbjct: 172 MLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINY 231 Query: 238 LSWIKKTM 245 + WI+ + Sbjct: 232 IPWIENII 239 >4J1Y-A nrPDB Length = 397 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 71/264 (26%), Positives = 115/264 (43%), Gaps = 39/264 (14%) Query: 13 APKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI- 71 P E IGG +A + P+ + + GG LI E +VLTAAH Sbjct: 139 EPFEEKARAIGGSDADIKNFPWQVFFD-------NPWAGGALINEYWVLTAAHVVEGNRE 191 Query: 72 -NVTLGAHNIKEQE--KMQQIIPVVKIIPHPAYN-------SKTISNDIMLLKLKSKAKR 121 + +G+ +++ K + + P + HP + NDI L++LK K Sbjct: 192 PTMYVGSTSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKM 250 Query: 122 SSAVKPLNLP--RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCE---- 175 V P+ LP + + GD+ ++GWG+ + + L+ L V +KC+ Sbjct: 251 GPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKV 309 Query: 176 ----SYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKK-------VAAGIVSYGQND 224 + + Y N ICAG K S +GDSGG + AAG+VS+G Sbjct: 310 EKPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC 368 Query: 225 GSTPRAFTKVSTFLSWIKKTMKKS 248 G+ +T+V ++ WI KTM+++ Sbjct: 369 GTY-GLYTRVKNYVDWIMKTMQEN 391 >5KWM-A nrPDB Length = 230 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 17/226 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----GSKINVTLG 76 I+GG +A P+ L D G + CGG L + V+TAAHC+ + INV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPD---GQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + E + V + HP Y D+ +L L++ K P+ L + + Sbjct: 58 RTVMSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDA 111 Query: 137 -VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 P + GWG G+ +D LQ+ + V D C+ Y A +CAG P+ Sbjct: 112 GYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDA-MVCAGVPEG 170 Query: 196 KRASFRGDSGGPLVCKKVAAGIVSYGQNDGS--TPRAFTKVSTFLS 239 + +GDSGGP+V G+ S+G+ P + +V + Sbjct: 171 GVDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGKPGVYARVGAYYD 216 >5O32-I nrPDB Length = 244 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 105/237 (44%), Gaps = 23/237 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KINVTLG 76 I+GG A+ P+ + + + CGG I ++LTAAHC + + + Sbjct: 1 IVGGKRAQLGDLPWQVAI----KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 56 Query: 77 A-HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKP----LNLP 131 I K I V +II H YN+ T NDI L+++K + P +P Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 116 Query: 132 RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG 191 +P D C V+GWG+ + +LQ E+ + + C + N F + CAG Sbjct: 117 WSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 173 Query: 192 DPKIKRASFRGDSGGPLVCKK-----VAAGIVSYGQNDGST--PRAFTKVSTFLSWI 241 + +GDSGGPLVC G+VS+G+N G P +TKV+ + WI Sbjct: 174 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 230 >1PPF-E nrPDB Length = 218 Score = 222 bits (567), Expect = 9e-59, Method: Composition-based stats. Identities = 73/233 (31%), Positives = 112/233 (48%), Gaps = 22/233 (9%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVT----LG 76 I+GG A+PH+ P+M LQ+ G CG LI +FV++AAHC + LG Sbjct: 1 IVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 AHN+ +E +Q+ V +I Y+ + NDI++L+L A ++ V+ LP + + Sbjct: 57 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 115 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 196 + G C GWG LG + LQE+ +TV + + +C + Sbjct: 116 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV----------TSLCRRSNVCTLVRGRQ 165 Query: 197 RASFRGDSGGPLVCKKVAAGIVSY---GQNDGSTPRAFTKVSTFLSWIKKTMK 246 GDSG PLVC + GI S+ G G P AF V+ F++WI ++ Sbjct: 166 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >2B9L-A nrPDB Length = 394 Score = 218 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 69/251 (27%), Positives = 119/251 (47%), Gaps = 31/251 (12%) Query: 25 HEAKPHSRPYMAYLQIMDEYSGS----KKCGGFLIREDFVLTAAHCSGS------KINVT 74 +EA+ P+M + + GS CGG LI VLT AHC S I + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 75 LGAHN-IKEQEK-MQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 G + + E+E+ Q + ++I H +N KT+ ND+ LL L ++ + + LP+ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 133 RNVKVKPGDVCYVAGWGK--LGPMGKYSDTLQEVELTVQEDQKCESYLKN------YFDK 184 ++ C+ +GWGK G +YS+ L++++L + KC++ L+N + Sbjct: 255 QSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 185 ANEICAGDPKIKRASFRGDSGGPLVC-------KKVAAGIVSYGQNDG--STPRAFTKVS 235 +CAG + + + GD G PL C + + GIV++G G + P + V+ Sbjct: 314 QTFVCAGGEQ-GKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVA 372 Query: 236 TFLSWIKKTMK 246 F +WI + M+ Sbjct: 373 HFRNWIDQEMQ 383 >2HLC-A nrPDB Length = 230 Score = 210 bits (535), Expect = 4e-55, Method: Composition-based stats. Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 II G+EA PY A L I + CGG LI ++LTAAHC ++V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 140 + E + ++ +II H +N T ND+ L+K+ + + ++P+ LP Sbjct: 61 VQYEG-EAVVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPSGEELNNKF 118 Query: 141 DVCY--VAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 198 + + V+GWG+ + LQ V ++ +C + IC GD ++ Sbjct: 119 ENIWATVSGWGQSNTD---TVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 199 SFRGDSGGPLVC--KKVAAGIVSYGQNDGS---TPRAFTKVSTFLSWIKKT 244 GDSGGP V K + G+VS+ G P F++V++++ WI++ Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQN 225 >2ASU-B nrPDB Length = 234 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 106/240 (44%), Gaps = 28/240 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS------KINVT 74 ++GGH P + P+ L+ G CGG L++E ++LTA C S V Sbjct: 1 VVGGH---PGNSPWTVSLR---NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 75 LGAH--NIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 LG N + E Q +PV K++ P+ + ++LLKL+ + V + LP Sbjct: 55 LGTLFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPP 108 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD 192 V PG C +AGWG+ G + L L V +Q+C + + +E+C Sbjct: 109 EWYVVPPGTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKHRGRV-RESEMCTEG 166 Query: 193 PKIKRASFRGDSGGPLVC----KKVAAGIVSYGQNDGST--PRAFTKVSTFLSWIKKTMK 246 + GD GGPL C V GI+ + + P FT+VS F+ WI K M+ Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >3I77-A nrPDB Length = 230 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 26/240 (10%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS---GSKINVTLGA 77 ++GG A P+M L CGG L +D VLTAAHC G+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRL---INEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P + +T D L+KL +P+N P + Sbjct: 58 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLA---------QPINQPTLKIAT 108 Query: 138 KPGD---VCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 VAGWG G L + + D C S ICAG P Sbjct: 109 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPD 168 Query: 195 -IKRASFRGDSGGPLVCK-----KVAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMK 246 + +GDSGGP+ K + GIVS+G P +T+VSTF S I + Sbjct: 169 TGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAAR 228 >4X0L-C nrPDB Length = 259 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 65/267 (24%), Positives = 112/267 (41%), Gaps = 47/267 (17%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA------H-- 65 P I+GGH S P+ A + + G LI E ++LT A H Sbjct: 8 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTT----GATLINEQWLLTTAKNLFLNHSE 63 Query: 66 -CSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + I TL + +Q++ + K++ HP Y+ DI L+KLK K + Sbjct: 64 NATAKDIAPTLTLYV-----GKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNER 114 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN---- 180 V P+ LP ++ + G V YV+GWG+ K++D L+ V L V + +C + + Sbjct: 115 VMPICLPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVP 172 Query: 181 ------------YFDKANEICAGDPKIKRASFRGDSGGPLVCK------KVAAGIVSYGQ 222 + CAG K + + GD+G A GI+S+ + Sbjct: 173 EKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDK 232 Query: 223 NDG-STPRAFTKVSTFLSWIKKTMKKS 248 + + + KV++ W++KT+ ++ Sbjct: 233 SCAVAEYGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 65/267 (24%), Positives = 112/267 (41%), Gaps = 47/267 (17%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAA------H-- 65 P I+GGH S P+ A + + G LI E ++LT A H Sbjct: 64 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTT----GATLINEQWLLTTAKNLFLNHSE 119 Query: 66 -CSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 124 + I TL + +Q++ + K++ HP Y+ DI L+KLK K + Sbjct: 120 NATAKDIAPTLTLYV-----GKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNER 170 Query: 125 VKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN---- 180 V P+ LP ++ + G V YV+GWG+ K++D L+ V L V + +C + + Sbjct: 171 VMPICLPSKDY-AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVP 228 Query: 181 ------------YFDKANEICAGDPKIKRASFRGDSGGPLVCK------KVAAGIVSYGQ 222 + CAG K + + GD+G A GI+S+ + Sbjct: 229 EKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDK 288 Query: 223 NDG-STPRAFTKVSTFLSWIKKTMKKS 248 + + + KV++ W++KT+ ++ Sbjct: 289 SCAVAEYGVYVKVTSIQDWVQKTIAEN 315 >1PQ7-A nrPDB Length = 224 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 57/230 (24%), Positives = 86/230 (37%), Gaps = 17/230 (7%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSG----SKINVTLG 76 I+GG A P++ + +G CGG L+ + VLTAAHC S + G Sbjct: 1 IVGGTSASAGDFPFIVSI----SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 136 + + + V HP+Y+ ND+ +LKL + + L Sbjct: 57 SLSRTSGGITSSLSSVR---VHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 137 VKPGDVCYVAGWGKLGPMGKYSDT-LQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 195 G VAGWG G + L +V + + C + CAG Sbjct: 112 PVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSG 171 Query: 196 KRASFRGDSGGPLV-CKKVAAGIVSYGQNDG--STPRAFTKVSTFLSWIK 242 + S +GDSGGP+V G VS+G + + V S+I Sbjct: 172 GKDSCQGDSGGPIVDSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >4LK4-A nrPDB Length = 357 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 24/252 (9%) Query: 13 APKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYS-GSKKCGGFLIREDFVLTAAHCSGSK- 70 + + II G A P + L + + CGG + +VLTAAHC S+ Sbjct: 3 STADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRS 62 Query: 71 ---INVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKP 127 ++V +GA+++ + ++ I KI H +Y+ + NDI +++L +S++ Sbjct: 63 AASVDVIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPA 117 Query: 128 LNL--PRRNVKVKPGDVCYVAGWGKLGPMGK--YSDTLQEVELTVQEDQKCESYLKNYFD 183 + L P + VAGWG ++ LQEV++ + C+ +++ Sbjct: 118 ITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGIS 177 Query: 184 ---KANEICAGDPKIKRASFRGDSGGPLVCK--KVAAGIVSYGQNDGST---PRAFTKVS 235 + CA + S +GD+GGP+V K + GIVS+G + +T VS Sbjct: 178 SDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVS 235 Query: 236 TFLSWIKKTMKK 247 F WI K + Sbjct: 236 YFRDWITKHTNQ 247 >3BEU-A nrPDB Length = 224 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 65/239 (27%), Positives = 94/239 (39%), Gaps = 30/239 (12%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS---GSKINVTLGA 77 ++GG A P+M L + CGG L +D VLTAAHC G+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG--------CGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P + +T D L+KL +P+N P + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLA---------QPINQPTLKIAT 103 Query: 138 KPGD---VCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 VAGWG G L + + D C S ICAG Sbjct: 104 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDT 163 Query: 195 IKRASFRGDSGGPLVCK-----KVAAGIVSYGQNDGSTP--RAFTKVSTFLSWIKKTMK 246 + + +GDSGGP+ K V GIVS+G+ +T+VSTF S I + Sbjct: 164 KQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 222 >4F4O-C nrPDB Length = 347 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 66/268 (24%), Positives = 113/268 (42%), Gaps = 49/268 (18%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + I+GG S P+ A + + G LI E ++LT A N+ Sbjct: 96 PVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTS----GATLINEQWLLTTAK------NL 145 Query: 74 TLGAHN----------IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSS 123 LG N ++ +Q + + K+I HP ++ DI L+KLK K + Sbjct: 146 RLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV----DIGLIKLKQKVPVNE 201 Query: 124 AVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKN--- 180 V P+ LP ++ V G V YV+GWG+ + +++ L+ V L V + +KC Y + Sbjct: 202 RVMPICLPSKDY-VNVGLVGYVSGWGRNANL-NFTEHLKYVMLPVADQEKCVQYYEGSTV 259 Query: 181 -------------YFDKANEICAGDPKIKRASFRGDSGGPLVCK------KVAAGIVSYG 221 + CAG K + + GD+G AAGI+S+ Sbjct: 260 PEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFD 319 Query: 222 QNDGS-TPRAFTKVSTFLSWIKKTMKKS 248 ++ + + +V++ L WI+ T+ + Sbjct: 320 KSCRTAEYGVYVRVTSILDWIQTTIADN 347 >6BQM-A nrPDB Length = 506 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 109/247 (44%), Gaps = 27/247 (10%) Query: 18 AGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----GSKINV 73 + IIGG +A PYM L S CGG + +VLTAAHC +K +V Sbjct: 8 SSRIIGGEQATAGEWPYMVAL--TARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDV 65 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LGA ++ + ++ I V +I H +Y + ++ NDI +L+L+ +V+ ++ Sbjct: 66 LLGAFDMNDVNTAER-IHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSSD 123 Query: 134 NVKVKPGDVCYVAGWGK----LGPMGKYSDTLQEVELTVQEDQKCE-----SYLKNYF-- 182 ++ V G+G G + L +V++ +C+ KN + Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 183 DKANEICAGDPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVST 236 N CAG + + GD+GGP+ + G+VS+G G ++P +T +S Sbjct: 184 LTNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSV 241 Query: 237 FLSWIKK 243 F W+ Sbjct: 242 FNDWLDD 248 >1SI5-H nrPDB Length = 240 Score = 199 bits (507), Expect = 8e-52, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 107/240 (44%), Gaps = 29/240 (12%) Query: 21 IIGG--HEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KINVT 74 ++ G +M L+ Y CGG LI+E +VLTA C S Sbjct: 1 VVNGIPTRTNIG---WMVSLR----YRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAW 53 Query: 75 LGAHNI--KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR 132 LG H++ + EK +Q++ V +++ P +D++L+KL A V ++LP Sbjct: 54 LGIHDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPN 107 Query: 133 RNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFD-KANEICAG 191 + C V GWG G + Y L+ L + ++KC + + +EICAG Sbjct: 108 YGSTIPEKTSCSVYGWGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG 166 Query: 192 DPKIKRASFRGDSGGPLVCK----KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTM 245 KI GD GGPLVC+ ++ G++ G+ + P F +V+ + WI K + Sbjct: 167 AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >2FMJ-A nrPDB Length = 222 Score = 199 bits (507), Expect = 8e-52, Method: Composition-based stats. Identities = 67/239 (28%), Positives = 94/239 (39%), Gaps = 32/239 (13%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS---GSKINVTLGA 77 ++GG A P+M L + CGG L +D VLTAAHC G+ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG--------CGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 78 HNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 137 + Q + K++ P YN D L+KL +P+N P + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLA---------QPINQPTLKIAT 101 Query: 138 KPGD---VCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPK 194 VAGWG G L + + D C S N EICAG Sbjct: 102 TTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDT 161 Query: 195 IKRASFRGDSGGPLVCK-----KVAAGIVSYGQNDGSTP--RAFTKVSTFLSWIKKTMK 246 + +GDSGGP+ K + GIVS+G+ +T+VSTF S I + Sbjct: 162 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 220 >5XW8-A nrPDB Length = 133 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 58/139 (41%), Positives = 76/139 (54%), Gaps = 7/139 (5%) Query: 14 PKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINV 73 P + +I+GG+ +S PY L SGS CGG LI +V++AAHC S+I V Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSLN-----SGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 74 TLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRR 133 LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V ++LPR Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 134 NVKVKPGDVCYVAGWGKLG 152 G C ++GWG Sbjct: 117 C--AAAGTECLISGWGNTK 133 >3H7O-A nrPDB Length = 228 Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats. Identities = 61/229 (26%), Positives = 99/229 (43%), Gaps = 7/229 (3%) Query: 23 GGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKI--NVTLGAHNI 80 GG + P+ ++ S CGG ++ + FVLTAAHC + + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTY-PGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYEST 60 Query: 81 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSS-AVKPLNLPRRNVKVKP 139 E + P V + Y +T+ NDI +L+L K KP LP + K Sbjct: 61 NLWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 140 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 199 G V+G+G M L+ +LTV + +C + F CA K+ + Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQ--KVGVSL 178 Query: 200 FRGDSGGPLVCKKVAAGIVS-YGQNDGSTPRAFTKVSTFLSWIKKTMKK 247 GD+G P V + G+ + + + P FTKV +++SWI+ +KK Sbjct: 179 ESGDAGDPTVQQDTLVGVAAYFPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >1M9U-A nrPDB Length = 241 Score = 188 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 93/242 (38%), Gaps = 20/242 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----GSKINVTLG 76 +IGG A P P+ Q S S CG L+ L+A+HC + I V G Sbjct: 1 VIGGTNASPGEFPWQLSQQ-RQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKT--ISNDIMLLKLKSKAKRSSAVKPLNLPRRN 134 + Q V H Y + T SNDI +L L + ++ LP N Sbjct: 60 LWQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYL---KNYFDKANEICAG 191 G C ++GWG+ D LQ+ + V +C + + N IC Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 192 DPKIKRASFRGDSGGPLVCKK---VAAGIVSYGQNDG------STPRAFTKVSTFLSWIK 242 DP + GDSGGPL C G+ S+ + G P +T+VS +L WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWIG 238 Query: 243 KT 244 Sbjct: 239 DN 240 >2PKA-B nrPDB Length = 152 Score = 183 bits (466), Expect = 4e-47, Method: Composition-based stats. Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 9/151 (5%) Query: 104 KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMG---KYSDT 160 K S+D+MLL+L+S AK + AVK L LP + ++ G C +GWG + P ++ D Sbjct: 4 KDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFPDE 61 Query: 161 LQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSY 220 +Q V+LT+ ++ C + + +CAG + + GDSGGPL+C + GI S+ Sbjct: 62 IQCVQLTLLQNTFCADAHPDKV-TESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSW 120 Query: 221 G---QNDGSTPRAFTKVSTFLSWIKKTMKKS 248 G + P +TK+ +L WI T+ ++ Sbjct: 121 GHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >3H7T-A nrPDB Length = 235 Score = 174 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 57/236 (24%), Positives = 96/236 (40%), Gaps = 19/236 (8%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCS----GSKINVTLG 76 IIGG ++ P+ + + ++ CGG ++ +FV+TAA C S I++ G Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEK----PFCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 77 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSS-AVKPLNLPRRNV 135 + + + KI Y+ T+ N+ +++ + K K + LP Sbjct: 57 S---SYRTTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLY 112 Query: 136 KVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLK----NYFDKANEICA 190 +P V+GWG +YS L E TV + + CE K + + CA Sbjct: 113 DPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCA 172 Query: 191 GDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGST-PRAFTKVSTFLSWIKKTM 245 G + GD+G P V G+ SY + S P F +V ++ IK + Sbjct: 173 GGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDII 228 >3VGC-B nrPDB Length = 131 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 48/133 (36%), Positives = 68/133 (51%), Gaps = 4/133 (3%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL-GAHN 79 I+ G EA P S P+ LQ + +G CGG LI E++V+TAAHC + +V + G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 57 Query: 80 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 139 + Q + + K+ + YNS TI+NDI LLKL + A S V + LP + Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 117 Query: 140 GDVCYVAGWGKLG 152 G C GWG Sbjct: 118 GTTCVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 48/130 (36%), Positives = 70/130 (53%), Gaps = 4/130 (3%) Query: 24 GHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL-GAHNIKE 82 G +A P S P+ LQ + +G CGG LI ED+V+TAAHC +V + G + Sbjct: 1 GEDAIPGSWPWQVSLQ---DKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGS 57 Query: 83 QEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDV 142 E+ Q++ + ++ +P +N T+ NDI LLKL + A+ S V + LP + PG V Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 143 CYVAGWGKLG 152 C GWGK Sbjct: 118 CATTGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 17/149 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + + Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 71 INVTLGAHNIKEQEKM-QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPL 128 + V +G H+ E+ ++I + KI HP YN + + DI L+KLK S + P+ Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 129 NLPRRNVK---VKPGDVCYVAGWGKLGPM 154 LP R ++ G V GWG L Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 154 bits (389), Expect = 4e-38, Method: Composition-based stats. Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 17/152 (11%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 71 INVTLGAHNIKEQE-KMQQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPL 128 + V +G H+ E K+++I + KI HP YN + + DI LLKLK + S + P+ Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 129 NLPRRNVKVK---PGDVCYVAGWGKLGPMGKY 157 LP + K G V GWG Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTT 150 >2WIN-I nrPDB Length = 507 Score = 151 bits (383), Expect = 2e-37, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 68/251 (27%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQI 89 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK ++ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 287 Query: 90 -IPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----RRN 134 + + ++ HP YN + D+ L+KLK+K K ++P+ LP R Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 347 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTL---QEVELTVQEDQK------------------ 173 +++ P C + + L Q+++ +++ Sbjct: 348 LRLPPTTTCQ-----------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 396 Query: 174 CE---SYLKNY--------FDKANEICAGD--PKIKRASFRGDSGGPLVCKK----VAAG 216 CE Y Y +C G P + RGDSGGPL+ K + G Sbjct: 397 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 456 Query: 217 IVSYGQNDGST 227 ++S+G D Sbjct: 457 VISWGVVDVCK 467 >1DLE-A nrPDB Length = 298 Score = 150 bits (379), Expect = 5e-37, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 68/251 (27%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQI 89 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK ++ Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 80 Query: 90 -IPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----RRN 134 + + ++ HP YN + D+ L+KLK+K K ++P+ LP R Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 140 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTL---QEVELTVQEDQK------------------ 173 +++ P C + + L Q+++ +++ Sbjct: 141 LRLPPTTTCQ-----------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 189 Query: 174 CE---SYLKNY--------FDKANEICAGD--PKIKRASFRGDSGGPLVCKK----VAAG 216 CE Y Y +C G P + RGDSGGPL+ K + G Sbjct: 190 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 249 Query: 217 IVSYGQNDGST 227 ++S+G D Sbjct: 250 VISWGVVDVCK 260 >2OK5-A nrPDB Length = 752 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 68/251 (27%) Query: 30 HSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQI 89 H +P+ A + ++ G + C G ++ E FVLTAAHC V H+IK ++ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC----FTVDDKEHSIKVSVGGEKR 531 Query: 90 -IPVVKIIPHPAYN---------SKTISNDIMLLKLKSKAKRSSAVKPLNLP-----RRN 134 + + ++ HP YN + D+ L+KLK+K K ++P+ LP R Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 591 Query: 135 VKVKPGDVCYVAGWGKLGPMGKYSDTL---QEVELTVQEDQK------------------ 173 +++ P C + + L Q+++ +++ Sbjct: 592 LRLPPTTTCQ-----------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 640 Query: 174 CE---SYLKNY--------FDKANEICAGD--PKIKRASFRGDSGGPLVCKK----VAAG 216 CE Y Y +C G P + RGDSGGPL+ K + G Sbjct: 641 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 700 Query: 217 IVSYGQNDGST 227 ++S+G D Sbjct: 701 VISWGVVDVCK 711 >1AKS-B nrPDB Length = 98 Score = 144 bits (363), Expect = 4e-35, Method: Composition-based stats. Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Query: 152 GPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCK 211 Y LQ ++ V + C+S N IC G + + S +GDSGGP+VC Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQI-TGNMICVGFLQGGKDSCQGDSGGPVVCN 59 Query: 212 KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 GIVS+G + P +TKV +++WI++T+ + Sbjct: 60 GQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >2KAI-A nrPDB Length = 80 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNI 80 IIGG E + +S P+ + + S +CGG L+ +VLTAAHC V LG HN+ Sbjct: 1 IIGGRECEKNSHPWQVAIY----HYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL 56 Query: 81 KEQEKMQQIIPVVKIIPHPAYN 102 E E Q V PHP +N Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >1EPT-B nrPDB Length = 82 Score = 113 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 37/84 (44%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Query: 69 SKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPL 128 S+I V LG HNI E +Q I KII HP +N T+ NDIML+KL S A +S V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 129 NLPRRNVKVKPGDVCYVAGWGKLG 152 +LPR G C ++GWG Sbjct: 61 SLPRSC--AAAGTECLISGWGNTK 82 >3F1S-B nrPDB Length = 283 Score = 112 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 53/227 (23%), Positives = 90/227 (39%), Gaps = 30/227 (13%) Query: 33 PYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH-NIKEQEKMQQIIP 91 P+ L G CGG +IRE+FVLT A CS N+T+ + N Q+ + +I Sbjct: 65 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIK 119 Query: 92 VVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGW 148 + + H Y++ ND+ LL+L+ + A P+ P ++ + P ++GW Sbjct: 120 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 179 Query: 149 GKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEIC----AGDPKIKRASFRGDS 204 + G ++L +T+ E ++C L N C S Sbjct: 180 ARNGT--DLGNSLTTRPVTLVEGEECGQVL-NVTVTTRTYCERSSVAAMHWMDGS----- 231 Query: 205 GGPLVCK-----KVAAGIV-SYGQNDGSTPRAFTKVSTFLSWIKKTM 245 +V + G++ S + TKVS + W K+ M Sbjct: 232 ---VVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >1BBR-E nrPDB Length = 109 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 12/102 (11%) Query: 157 YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK-- 211 LQ V L + E C++ + N CAG + + GDSGGP V K Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 212 ----KVAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ +T V WI+K + + Sbjct: 65 YNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2HNT-F nrPDB Length = 105 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 12/102 (11%) Query: 157 YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGD---PKIKRASFRGDSGGPLVCK-- 211 LQ V L + E C+ + N CAG + + GDSGGP V K Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 60 Query: 212 ----KVAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMKK 247 GIVS+G+ +T V WI+K + + Sbjct: 61 FNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >3RU4-E nrPDB Length = 96 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 9/99 (9%) Query: 156 KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCK---- 211 D LQ+ L + + C+ Y K ICAG +S GDSGGPLVCK Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKI-KDAMICAGAS--GVSSCMGDSGGPLVCKKNGA 57 Query: 212 KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 GIVS+G + STP + +V+ ++W+++T+ + Sbjct: 58 WTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 96 >3H5C-B nrPDB Length = 317 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 53/227 (23%), Positives = 90/227 (39%), Gaps = 30/227 (13%) Query: 33 PYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAH-NIKEQEKMQQIIP 91 P+ L G CGG +IRE+FVLT A CS N+T+ + N Q+ + +I Sbjct: 106 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIK 160 Query: 92 VVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDVCYVAGW 148 + + H Y++ ND+ LL+L+ + A P+ P ++ + P ++GW Sbjct: 161 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 220 Query: 149 GKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEIC----AGDPKIKRASFRGDS 204 + G ++L +T+ E ++C L N C S Sbjct: 221 ARNGT--DLGNSLTTRPVTLVEGEECGQVL-NVTVTTRTYCERSSVAAMHWMDGS----- 272 Query: 205 GGPLVCK-----KVAAGIV-SYGQNDGSTPRAFTKVSTFLSWIKKTM 245 +V + G++ S + TKVS + W K+ M Sbjct: 273 ---VVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2JET-C nrPDB Length = 99 Score = 107 bits (267), Expect = 5e-24, Method: Composition-based stats. Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 9/99 (9%) Query: 156 KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCK---- 211 K + LQ+ L + + C+ + CAG S GDSGGPLVC+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDV-MTCAGAS--GVDSCMGDSGGPLVCQKDGV 60 Query: 212 KVAAGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 248 AGIVS+G STP +++V+ + W+++ ++ + Sbjct: 61 WTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILEAN 99 >2I6S-A nrPDB Length = 517 Score = 103 bits (257), Expect = 9e-23, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 83/242 (34%), Gaps = 63/242 (26%) Query: 33 PYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-----INVTLGAHNIKEQEKMQ 87 P+ ++ + C G LI + +VLTAAHC V +G + + Sbjct: 244 PWHVTIKPKS----QETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG----DPKSQWG 295 Query: 88 QIIPVVKIIPHPAYNS---------KTISNDIMLLKLKSKAKRSSAVKPLNLP---RRNV 135 + + K + P ++ + +DI LLKL K K S+ +P+ LP N+ Sbjct: 296 KEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANL 355 Query: 136 KV--KPGDVCYVAGWGKLGPMGKYSDT--------LQEVELTV-----QEDQKCESY--- 177 + G C + + L +L + E C Sbjct: 356 ALRRPQGSTC------RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 409 Query: 178 ----LKNYFD-----KANEICAGDPKIKRASFRGDSGGPLV----CKKVAAGIVSYGQND 224 N D +C+G + + +G+SGG + + G+VS+G + Sbjct: 410 EKTMFPNLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWGLYN 468 Query: 225 GS 226 Sbjct: 469 PC 470 >2HNT-E nrPDB Length = 81 Score = 85.6 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 87 QQIIPVVKIIPHPAYNS-KTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK---VKPGDV 142 ++I + KI HP YN + + DI L+KLK S + P+ LP R ++ G Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 143 CYVAGWGKLGPMGK 156 V GWG L Sbjct: 63 GRVTGWGNLKETWT 76 >2HNT-C nrPDB Length = 70 Score = 77.9 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 12/72 (16%) Query: 21 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----------SGSK 70 I+ G +A+ P+ L + CG LI + +VLTAAHC + + Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 71 INVTLGAHNIKE 82 + V +G H+ Sbjct: 59 LLVRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 38/112 (33%), Gaps = 16/112 (14%) Query: 46 GSKKCGGFLIREDFVLTAAHC--------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIP 97 G C G LI + +LT HC +K +V G ++ + + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANM---TEFYV 84 Query: 98 HPAY-NSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGW 148 Y N+ D ++K + + + + R V G ++G+ Sbjct: 85 PSGYINTGASQYDFAVIKTDTNIGNTVGYRSI----RQVTNLTGTTIKISGY 132 >2PFE-A nrPDB Length = 186 Score = 37.8 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 14/29 (48%) Query: 202 GDSGGPLVCKKVAAGIVSYGQNDGSTPRA 230 GDSGGP + A G+ S G D + Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDCRSGGI 166 >2EA3-A nrPDB Length = 189 Score = 35.9 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 202 GDSGGPLVCKKVAAGIVSYGQNDGSTPR 229 GDSGG L+ A G+ S G + T Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2OUA-A nrPDB Length = 188 Score = 35.5 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 49/180 (27%), Gaps = 53/180 (29%) Query: 61 LTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 +TA HC V++G + + + P ND ++ S Sbjct: 31 VTAGHCGSVGTQVSIG---------NGRGVFERSVFP---------GNDAAFVRGTSNFT 72 Query: 121 RSSAV--------KPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQ 172 ++ V + + G +G G Y T+Q TV Sbjct: 73 LTNLVSRYNSGGYATV---SGSSTAPIGSQVCRSG----STTGWYCGTIQARNQTV---- 121 Query: 173 KCESYLKNYFD---KANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR 229 +CA GDSGG + A G+ S G + T Sbjct: 122 ----SYPQGTVHSLTRTSVCAEP---------GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >5ILB-A nrPDB Length = 474 Score = 35.5 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 32/89 (35%), Gaps = 19/89 (21%) Query: 25 HEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQE 84 H A +S P+ Q S F+I + +LT AHC V K + Sbjct: 17 HTAPDYSLPWQKQRQFTSTGS------AFMIGDGKLLTNAHCVEHDTQV-------KVKR 63 Query: 85 KMQQIIPVVKIIPHPAYNSKTISNDIMLL 113 + V K++ + + DI LL Sbjct: 64 RGDDRKYVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 35.5 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 32/89 (35%), Gaps = 19/89 (21%) Query: 25 HEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQE 84 H A +S P+ Q S F+I + +LT AHC V K + Sbjct: 57 HTAPDYSLPWQKQRQFTSTGS------AFMIGDGKLLTNAHCVEHDTQV-------KVKR 103 Query: 85 KMQQIIPVVKIIPHPAYNSKTISNDIMLL 113 + V K++ + + DI LL Sbjct: 104 RGDDRKYVAKVLV------RGVDCDIALL 126 >2SFA-A nrPDB Length = 191 Score = 34.4 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 16/45 (35%), Gaps = 9/45 (20%) Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR 229 +CA GDSGG L A G+ S G + T Sbjct: 137 QTNVCAEP---------GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >2SGA-A nrPDB Length = 181 Score = 33.2 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 16/45 (35%), Gaps = 9/45 (20%) Query: 185 ANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR 229 +CA GDSGG L A G+ S G + T Sbjct: 127 QTNVCAQP---------GDSGGSLFAGSTALGLTSGGSGNCRTGG 162 >3LT3-A nrPDB Length = 217 Score = 32.4 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 55/168 (32%), Gaps = 32/168 (19%) Query: 52 GFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIM 111 GF+I D V+T AH V G++N+ + V Y+ D+ Sbjct: 42 GFVISPDRVMTNAH-------VVAGSNNVTVYAGDKPFEATVVS-----YDPSV---DVA 86 Query: 112 LLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQED 171 +L A PL K G V G+ G ++E + + Sbjct: 87 IL-----AVPHLPPPPLVF--AAEPAKTGADVVVLGYPGGGNFTATPARIREA-IRLSGP 138 Query: 172 QKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLV-CKKVAAGIV 218 + ++ I+ +GD+GGPL+ G+V Sbjct: 139 D----IYGDPEPVTRDV----YTIRADVEQGDAGGPLIDLNGQVLGVV 178 >3W95-A nrPDB Length = 171 Score = 32.4 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 19/49 (38%), Gaps = 6/49 (12%) Query: 175 ESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN 223 Y + + G + GD+GG L C+ GIVS G N Sbjct: 108 SEYYPARYQSHLMLAQGHSEP------GDAGGILRCQHGVVGIVSTGGN 150 >4FVB-A nrPDB Length = 152 Score = 32.4 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 19/49 (38%), Gaps = 6/49 (12%) Query: 175 ESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQN 223 Y + + G + GD+GG L C+ GIVS G N Sbjct: 89 SEYYPARYQSHLMLAQGHSEP------GDAGGILRCQHGVVGIVSTGGN 131 >2HRV-A nrPDB Length = 142 Score = 30.5 bits (68), Expect = 0.62, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 19/48 (39%), Gaps = 7/48 (14%) Query: 175 ESYLKNYFDKANEICAGDPKIKRASFR-GDSGGPLVCKKVAAGIVSYG 221 ES + N + I GD GG L+CK GIV+ G Sbjct: 82 ESEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >3H7V-A nrPDB Length = 330 Score = 30.5 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 31/88 (35%), Gaps = 10/88 (11%) Query: 61 LTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAK 120 LT A G + E E+ Q + +I P P + S+T++ DI L + + Sbjct: 16 LTTA---QGVWRSRSGIYLRLEDEQGQ--VGYGEIAPLPGWGSETLNADIALCQ-----Q 65 Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAGW 148 + P + + + W Sbjct: 66 LPGHLTPEIMATIPEALPAAQFGFATAW 93 >5JYK-A nrPDB Length = 566 Score = 30.1 bits (67), Expect = 0.85, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 34/111 (30%), Gaps = 23/111 (20%) Query: 31 SRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQII 90 S P+ Q S GF+I VLT AH V L K + + Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHTQVKL----KKRGSDTKYLA 164 Query: 91 PVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLN---LPRRNVKVK 138 V+ I DI LL + + V P+ LP V Sbjct: 165 TVLAI---------GTECDIALLTVTDD-EFWEGVSPVEFGDLPALQDAVT 205 >5XIP-A nrPDB Length = 498 Score = 30.1 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 121 RSSAVKPLNLPRRNVKVKPGDVCYVAG 147 + A+KPL +P + G C+ G Sbjct: 459 MTGAMKPLCIPFDQPPMPEGTRCFFTG 485 >4XZB-A nrPDB Length = 314 Score = 29.7 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%) Query: 134 NVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVE 165 + ++ G +V+ WG G L+E E Sbjct: 218 DAALQAGTPVFVSEWGTSDASGDGGPYLEEAE 249 >5ILA-A nrPDB Length = 301 Score = 29.7 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 16/45 (35%), Gaps = 6/45 (13%) Query: 31 SRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTL 75 S P+ Q S GF+I VLT AH V L Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHTQVKL 153 >4V1Y-A nrPDB Length = 494 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 23/59 (38%), Gaps = 6/59 (10%) Query: 55 IREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSK-TISNDIML 112 + + +V H +I V LG H ++I + P + + T N I+L Sbjct: 41 LGDSWV----HVQDGRI-VALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILL 94 >4NCX-A nrPDB Length = 506 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%) Query: 110 IMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAG 147 + L + S+ S A+KPL +P + P C+ +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >1HPG-A nrPDB Length = 187 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 13/36 (36%), Gaps = 2/36 (5%) Query: 196 KRASFR--GDSGGPLVCKKVAAGIVSYGQNDGSTPR 229 + + GDSGG VA GI S T Sbjct: 133 RTTACSAGGDSGGAHFAGSVALGIHSGSSGCSGTAG 168 >2M5T-A nrPDB Length = 142 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 20/48 (41%), Gaps = 7/48 (14%) Query: 175 ESYLKNYFDKANEICAGDPKIKRASFR-GDSGGPLVCKKVAAGIVSYG 221 E+ + N + I GD+GG L+C+ GI++ G Sbjct: 81 ETQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAG 122 >5XIG-A nrPDB Length = 500 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 15/39 (38%), Gaps = 8/39 (20%) Query: 120 KRSSAVKPLNLPRRNVKVKPGDVCYVAG--------WGK 150 + A+K L +P + G C+ G WG+ Sbjct: 460 VMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGR 498 >1DUE-A nrPDB Length = 242 Score = 27.8 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 37/108 (34%), Gaps = 16/108 (14%) Query: 52 GFLIREDFVLTAAHC--------SGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNS 103 G LI ++ VLT H S ++ + E V +I+ P Sbjct: 59 GVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEP---- 114 Query: 104 KTISNDIMLLKLKSK---AKRSSAVKPLNLPRRNVKVKPGDVCYVAGW 148 D+ L++LK + P + N +K GD + G+ Sbjct: 115 FGAGVDLALIRLKPDQNGVSLGDKISPAKIGTSN-DLKDGDKLELIGY 161 >4NSY-A nrPDB Length = 275 Score = 27.8 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 12/30 (40%), Gaps = 6/30 (20%) Query: 43 EYSGSKKCGGFLIRED------FVLTAAHC 66 G+ C G L+ + LTA HC Sbjct: 29 SKQGTMWCTGSLVNNSANDKKMYFLTANHC 58 >4DP3-A nrPDB Length = 608 Score = 27.4 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 12/25 (48%) Query: 88 QIIPVVKIIPHPAYNSKTISNDIML 112 QI +K HP Y I DIM+ Sbjct: 313 QIYNSLKYKYHPEYQYLNIIYDIMM 337 >3DGA-C nrPDB Length = 328 Score = 27.4 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 12/25 (48%) Query: 88 QIIPVVKIIPHPAYNSKTISNDIML 112 QI +K HP Y I DIM+ Sbjct: 33 QIYNSLKYKYHPEYQYLNIIYDIMM 57 >2CTL-A nrPDB Length = 97 Score = 27.4 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 27/78 (34%), Gaps = 10/78 (12%) Query: 82 EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLL---KLKSKAKRSSAVKPLNLPRRNVKVK 138 EQE + + P Y+ K I ++ +L+ + P ++ + Sbjct: 8 EQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVN-------IQFPDKDDGNQ 60 Query: 139 PGDVCYVAGWGKLGPMGK 156 P D + G+ K + Sbjct: 61 PQDQITITGYEKNTEAAR 78 >1CDO-A nrPDB Length = 374 Score = 27.4 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 23/65 (35%), Gaps = 15/65 (23%) Query: 99 PAYNSKTISNDIMLLKLKSKAKRSSAVKPLNL-----------PRRNVKVKPGDVCYVAG 147 ++ T+ N I + K+ A + L KV+PG C V G Sbjct: 145 STFSQYTVVNQIAVAKIDPSAPLD----TVCLLGCGVSTGFGAAVNTAKVEPGSTCAVFG 200 Query: 148 WGKLG 152 G +G Sbjct: 201 LGAVG 205 >5NZU-C nrPDB Length = 905 Score = 27.0 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 27/60 (45%), Gaps = 6/60 (10%) Query: 58 DFVLTAAHCSGSKINVTLGAHN-IKEQEKMQQIIPVVKII-PHPAYNSKTISNDIMLLKL 115 ++V+T A + + + +N ++ + ++ I HP S+D ML+KL Sbjct: 70 NWVVTGA----DDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKL 125 >4B6E-A nrPDB Length = 683 Score = 27.0 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 171 KGSSGGPLLCPSGHAVGI 188 >6FE6-A nrPDB Length = 165 Score = 27.0 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 115 KGSSGGPLLCPSGHAVGI 132 >4NWK-A nrPDB Length = 219 Score = 27.0 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 151 KGSSGGPLLCPAGHAVGI 168 >6C2N-A nrPDB Length = 203 Score = 27.0 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 157 KGSSGGPLLCPAGHAVGI 174 >4U01-A nrPDB Length = 203 Score = 27.0 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 137 KGSSGGPLLCPSGHAVGI 154 >4K8B-A nrPDB Length = 181 Score = 27.0 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 201 RGDSGGPLVC-KKVAAGI 217 +G SGGPL+C A GI Sbjct: 136 KGSSGGPLLCPSGHAVGI 153 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.163 0.604 Lambda K H 0.267 0.0504 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,687,389 Number of Sequences: 36641 Number of extensions: 541182 Number of successful extensions: 2759 Number of sequences better than 10.0: 200 Number of HSP's better than 10.0 without gapping: 334 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 1162 Number of HSP's gapped (non-prelim): 382 length of query: 248 length of database: 10,336,785 effective HSP length: 95 effective length of query: 153 effective length of database: 6,855,890 effective search space: 1048951170 effective search space used: 1048951170 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.7 bits)