BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P18074 (760 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5IY7-W nrPDB 1572 0.0 5OQJ-0 nrPDB 798 0.0 5H8W-A nrPDB 64 2e-10 3CRV-A nrPDB 51 2e-06 2VL7-A nrPDB 43 4e-04 6FWS-A nrPDB 37 0.034 3ZIU-A nrPDB 33 0.34 4PAW-A nrPDB 32 0.93 3AYR-A nrPDB 30 4.8 4UAO-A nrPDB 29 8.6 >5IY7-W nrPDB Length = 760 Score = 1572 bits (4071), Expect = 0.0, Method: Compositional matrix adjust. Identities = 760/760 (100%), Positives = 760/760 (100%) Query: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ Sbjct: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 Query: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE Sbjct: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 Query: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL Sbjct: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180 Query: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID Sbjct: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240 Query: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE Sbjct: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300 Query: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG Sbjct: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360 Query: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP Sbjct: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420 Query: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT Sbjct: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480 Query: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT Sbjct: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540 Query: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA Sbjct: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600 Query: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA Sbjct: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660 Query: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF Sbjct: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720 Query: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL Sbjct: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760 >5OQJ-0 nrPDB Length = 778 Score = 798 bits (2061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/747 (51%), Positives = 524/747 (70%), Gaps = 6/747 (0%) Query: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 MK +D L V FPY IYPEQ++YM ++K+TLD G+ +LEMPSGTGKTVSLL+L +AYQ Sbjct: 1 MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQ 60 Query: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 YP E K+IYCSRT+ EIEK + EL L+++ K+ G + F GL L+SRKNLC+HPE Sbjct: 61 MHYP-EHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPE 119 Query: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHD--TSLPHCRFYEEFDAHGREVPLPAGIYNLD 178 V+ R G VD KC +T + + + D ++ C ++E E LP G+++ + Sbjct: 120 VSKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFE 179 Query: 179 DLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHN 238 L + CPYF+ R I N+++YSYHYLLDPKIA+ VS E+++ ++V+FDEAHN Sbjct: 180 KLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHN 239 Query: 239 IDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAA 298 IDNVCI+S+S++LT L R L + + +++ D Q+L+DEY +LV+GL Sbjct: 240 IDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLXXXXXX 299 Query: 299 RETDAHLANPVLPDEVLQEAVPGSIRT-AEHFLGFLRRLLEYVKWRLRVQHVVQESPPAF 357 AEHF+ FL+RL+EY+K R++V HV+ E+P +F Sbjct: 300 XXXXXXXXXXXXXXXXXXXXXXXXXXXRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSF 359 Query: 358 LSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTII 417 L L Q I+RKPLRFC+ERL L+ TLE+T++ DF+ L +A FATL+STY +GF +I Sbjct: 360 LQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLI 419 Query: 418 IEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVT 477 IEP++ + NPI+ F+C+DAS+AIKPVFERF SVIITSGT+SPLD+YP++L+F V Sbjct: 420 IEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVL 479 Query: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVA 537 ++ MTLA+ PMII +G+DQVAISS+FE R D +++RNYG++L+E + + PDG+V Sbjct: 480 QKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVV 539 Query: 538 FFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILL 597 FF SY YMES V+ W GIL+ + ++KL+ +ET D ETS+ALE Y++AC NGRGAILL Sbjct: 540 FFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILL 599 Query: 598 SVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAM 657 SVARGKVSEGIDF H YGR V+M G+P+ YT+SRILKARLE++R+ ++IRENDFL+FDAM Sbjct: 600 SVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAM 659 Query: 658 RHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVA 717 RHAAQC+GR +RGK DYG+MV AD+RF+R KR +LP+WI + L+DA+LNL+ D + Sbjct: 660 RHAAQCLGRVLRGKDDYGVMVLADRRFSR--KRSQLPKWIAQGLSDADLNLSTDMAISNT 717 Query: 718 KYFLRQMAQPFHREDQLGLSLLSLEQL 744 K FLR MAQP +DQ G+S+ S E L Sbjct: 718 KQFLRTMAQPTDPKDQEGVSVWSYEDL 744 >5H8W-A nrPDB Length = 597 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/241 (25%), Positives = 106/241 (43%), Gaps = 41/241 (17%) Query: 35 KGHGV-LEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNF 93 K +GV LE P+G+GKT+ L + Y L K++Y RT + E+VI+ELR L Sbjct: 3 KSYGVALESPTGSGKTIMALKSALQYSSERKL---KVLYLVRTNSQEEQVIKELRSL--- 56 Query: 94 YEKQEGEKLPFLGLALSSRKNLCI--------HPEVTPLRFGKDVDGKCHSLTASYVRAQ 145 + + + R N+CI H E+ K + K + A Sbjct: 57 -----SSTMKIRAIPMQGRVNMCILYRMVDDLH-EINAESLAKFCNMKKREVMAG----- 105 Query: 146 YQHDTSLPHCRFYEEFDAHGR----EVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILH 201 ++ + P+ F D R E+P Y+ G R CPY + ++ Sbjct: 106 --NEAACPYFNFKIRSDETKRFLFDELPTAEEFYD------YGERNNVCPYESMKAALPD 157 Query: 202 ANVVVYSYHYLLDPKIAD--LVSKELAR-KAVVVFDEAHNIDNVCIDSMSVNLTRRTLDR 258 A++V+ Y Y L+ +A+ L ++R + V++ DEAHN+ ++ S ++ +L+R Sbjct: 158 ADIVIAPYAYFLNRSVAEKFLSHWGVSRNQIVIILDEAHNLPDIGRSIGSFRISVESLNR 217 Query: 259 C 259 Sbjct: 218 A 218 Score = 37.0 bits (84), Expect = 0.029, Method: Compositional matrix adjust. Identities = 59/282 (20%), Positives = 113/282 (40%), Gaps = 53/282 (18%) Query: 454 VIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVA----ISSKFE 509 I SGTL P D Y I F + ++ I N +A +SSK++ Sbjct: 360 TIHMSGTLDPFDFYSDI--------TGFEIPFKKIG---EIFPPENRYIAYYDGVSSKYD 408 Query: 510 TREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFI 569 T ++ + R ++ ++ V + +F SY M+ N++ F Sbjct: 409 TLDEKELDR-MATVIEDIILKVKKNTIVYFPSYSLMDRV--------------ENRVSFE 453 Query: 570 ETQ-----DGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVP 624 + D E L+K++ ++G + +V+ G++SEGI+F + +I+ G+P Sbjct: 454 HMKEYRGIDQKELYSMLKKFRR--DHG---TIFAVSGGRLSEGINFPGNELEMIILAGLP 508 Query: 625 YVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRF 684 + + I ++ +Y ++ + + Q +GR IR D G V DKR Sbjct: 509 FPRPDA-INRSLFDYYCRKYGKGWEYSVVYPTAIKIRQEIGRLIRSAEDTGAAVILDKR- 566 Query: 685 ARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQ 726 G+ ++I ++ T D + +F+ A+ Sbjct: 567 -----AGQFRKFI------PDMKKTSDPASDIYNFFISAQAR 597 >3CRV-A nrPDB Length = 551 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 49/191 (25%), Positives = 89/191 (46%), Gaps = 30/191 (15%) Query: 502 VAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENI 561 V ++SK++ R D + + Y + LL++ ++ F SY+ M+ ++ I Sbjct: 364 VDVTSKYDMRSD-NMWKRYADYLLKIYFQAKANVLVVFPSYEIMDR---------VMSRI 413 Query: 562 QRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRA---- 617 K ++E++D + +E A ++ SV +GK++EGI+ ++ R+ Sbjct: 414 SLPK--YVESEDSS-----VEDLYSAISANNKVLIGSVGKGKLAEGIELRNN-DRSLISD 465 Query: 618 VIMFGVPYVYTQS--RILKARLEYLRDQFQIRENDFLTFD--AMRHAAQCVGRAIRGKTD 673 V++ G+PY +IL R+ + REN+ F A+ Q +GRAIR D Sbjct: 466 VVIVGIPYPPPDDYLKILAQRVSLKMN----RENEEFLFKIPALVTIKQAIGRAIRDVND 521 Query: 674 YGLMVFADKRF 684 + DKRF Sbjct: 522 KCNVWLLDKRF 532 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 16/138 (11%) Query: 180 LKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNI 239 LK G + +CPY+ S+ A+V+ +Y Y + + + +L R+ ++V DEAHN+ Sbjct: 127 LKKDGLQDKFCPYYSLLNSLYKADVIALTYPYFFIDRYREFIDIDL-REYMIVIDEAHNL 185 Query: 240 DNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAAR 299 D V L R+L T+Q + IK++ + R +L+ LRE Sbjct: 186 DKVN------ELEERSLSEI-----TIQ---MAIKQSKSEESRRILSKLLNQLREVVLPD 231 Query: 300 ETDAHLAN-PVLPDEVLQ 316 E + N P L E L+ Sbjct: 232 EKYIKVENVPKLSKEELE 249 >2VL7-A nrPDB Length = 540 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/192 (22%), Positives = 80/192 (41%), Gaps = 20/192 (10%) Query: 496 GRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQ 555 GRG + E R+ + I Y LL + ++ FF SY+ +ES Sbjct: 348 GRGEYYYCPNVTSELRKRNSNIPIYSILLKRIYENSSKSVLVFFPSYEMLESVRIHLSGI 407 Query: 556 GILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYG 615 ++E ++ + E+ E + G+ ++L V R K SEG++F Sbjct: 408 PVIEENKKTRH---------------EEVLELMKTGKYLVML-VMRAKESEGVEFREKEN 451 Query: 616 --RAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA-AQCVGRAIRGKT 672 ++++ G+PY +++ R+E L + ++ D + D Q +GRA R Sbjct: 452 LFESLVLAGLPYPNVSDDMVRKRIERL-SKLTGKDEDSIIHDLTAIVIKQTIGRAFRDPN 510 Query: 673 DYGLMVFADKRF 684 DY + D R+ Sbjct: 511 DYVKIYLCDSRY 522 Score = 35.4 bits (80), Expect = 0.10, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 56/108 (51%), Gaps = 12/108 (11%) Query: 189 WCPYFLARYSILHANVVVYSYHYLLDPKIADLV--SKELARKA---VVVFDEAHNIDNVC 243 +CPY+ R ++ +V+ +Y YL I + V +K+ K ++V DEAHN+ + Sbjct: 132 YCPYYSLRANLKDKDVIAMTYPYLFQKPIRNSVFCNKDDCLKLEDYLIVIDEAHNL--LE 189 Query: 244 IDS-MSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVE 290 D + ++R+ L+R +E ++ R+ D ++++D L++ Sbjct: 190 ADKWFTRKISRKMLERALKEIEIVE----RLNRIDAKKVKDYINLLID 233 >6FWS-A nrPDB Length = 716 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 53/230 (23%), Positives = 100/230 (43%), Gaps = 30/230 (13%) Query: 37 HGVLEMPSGTGKTVSLL--ALIMAYQRAYPLEVTKL-------IYCSRTVPEIEKVIEEL 87 H +E P+G GKT+S L + +A + L V+ IY S+ +P ++K+I +L Sbjct: 49 HLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIY-SKDLPLLKKIIPDL 107 Query: 88 RKLLNFYEKQE--GEKLPFLGLALSSRKNLC--IHPEVTPLRFGKDVDGKCHSLTASYVR 143 + F + L L ++++L + E+TP ++ +C L Sbjct: 108 KFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTP--NNQEEQKRCAKLKGDL-- 163 Query: 144 AQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGW---CPYFLARYSIL 200 Y+ D H + D R + D L R + CP+F+AR I Sbjct: 164 DTYKWDGLRDHTDIAIDDDLWRR--------LSTDKASCLNRNCYYYRECPFFVARREIQ 215 Query: 201 HANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVN 250 A VVV ++ ++ ++ V + + ++V DE H++ +V D++ ++ Sbjct: 216 EAEVVVANHALVMAAMESEAVLPD-PKNLLLVLDEGHHLPDVARDALEMS 264 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 16/111 (14%) Query: 581 LEKYQEACENGRGAILLSVARGKVSEGIDF-------VHHYGRAVIMFGVPYVYTQSRIL 633 +E +++ NG ++L+ + +EG+D VH + A P V T+ L Sbjct: 573 VELHRKRVANGERSVLVGLQ--SFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWL 630 Query: 634 KARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRF 684 K+ Y F+++ +F+ + Q VGR IR +G +V DKR Sbjct: 631 KSLNRY---PFEVQSLPSASFNLI----QQVGRLIRSHGCWGEVVIYDKRL 674 >3ZIU-A nrPDB Length = 637 Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 9/79 (11%) Query: 282 RDEYRRLV-EGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEY- 339 ++ +++L+ +G+ ++ L N V PDE++Q ++R E F+G L ++ Sbjct: 391 KEPFQKLINQGMILGKDGQKMSKSLGNVVNPDEIIQNFGADTLRVYEMFMGPLTDTKKWN 450 Query: 340 -------VKWRLRVQHVVQ 351 KW LRV+ + Q Sbjct: 451 ESTVEATYKWILRVKRIFQ 469 >4PAW-A nrPDB Length = 225 Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query: 198 SILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAH-NIDNVCIDSMSVNLTRRTL 256 S H+N + S L DPK+A+ ++ ELA++ EAH NI+ VC ++ L L Sbjct: 44 SGFHSNYYLQSAKVLEDPKLAEQLALELAKQ----IQEAHLNIECVCSPAIGGILAGYEL 99 Query: 257 DRCQG 261 R G Sbjct: 100 ARALG 104 >3AYR-A nrPDB Length = 376 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 28/52 (53%) Query: 216 KIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQ 267 KI D+ SKEL ++ ++ + +D CI+ ++ + + C GN +T + Sbjct: 14 KIRDISSKELIKEMNFGWNLGNTMDAQCIEYLNYEKDQTASETCWGNPKTTE 65 >4UAO-A nrPDB Length = 370 Score = 28.9 bits (63), Expect = 8.6, Method: Compositional matrix adjust. Identities = 24/105 (22%), Positives = 41/105 (39%), Gaps = 26/105 (24%) Query: 113 KNLCIHPEVTPLRFGKDVDGKCHSL---------------------TASYVRAQYQHDTS 151 +N C + +FG VDG C + +AS QY+ + + Sbjct: 204 ENKCPRKNLGNAKFGLWVDGNCEEIPYVNEVEARSLRECNRIVFEASASDQPRQYEEELT 263 Query: 152 LPHCRFYEEFDAHGREVP----LPAGIYNLDDLKALGRRQGWCPY 192 + + E F + R++ LP G +N D+ K+ GR W + Sbjct: 264 -DYEKIQEGFRQNNRDMIKSAFLPVGAFNSDNFKSKGRGYNWANF 307 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5IY7-W nrPDB 1221 0.0 5OQJ-0 nrPDB 1080 0.0 5H8W-A nrPDB 286 2e-77 2VL7-A nrPDB 207 1e-53 3CRV-A nrPDB 174 1e-43 Sequences not found previously or not previously below threshold: 6FWS-A nrPDB 49 1e-05 4JLV-A nrPDB 34 0.33 2WJV-A nrPDB 32 0.96 5BN5-A nrPDB 32 1.0 4UXV-A nrPDB 32 1.2 6EJ5-A nrPDB 32 1.3 4U5I-A nrPDB 31 1.6 2XZL-A nrPDB 31 1.6 2ONJ-A nrPDB 30 4.8 3H1T-A nrPDB 29 6.1 3L4G-A nrPDB 29 7.6 >5IY7-W nrPDB Length = 760 Score = 1221 bits (3159), Expect = 0.0, Method: Composition-based stats. Identities = 760/760 (100%), Positives = 760/760 (100%) Query: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ Sbjct: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 Query: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE Sbjct: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 Query: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL Sbjct: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180 Query: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID Sbjct: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240 Query: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE Sbjct: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300 Query: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG Sbjct: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360 Query: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP Sbjct: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420 Query: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT Sbjct: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480 Query: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT Sbjct: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540 Query: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA Sbjct: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600 Query: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA Sbjct: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660 Query: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF Sbjct: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720 Query: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL Sbjct: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760 >5OQJ-0 nrPDB Length = 778 Score = 1080 bits (2792), Expect = 0.0, Method: Composition-based stats. Identities = 384/755 (50%), Positives = 527/755 (69%), Gaps = 6/755 (0%) Query: 1 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60 MK +D L V FPY IYPEQ++YM ++K+TLD G+ +LEMPSGTGKTVSLL+L +AYQ Sbjct: 1 MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQ 60 Query: 61 RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120 YP E K+IYCSRT+ EIEK + EL L+++ K+ G + F GL L+SRKNLC+HPE Sbjct: 61 MHYP-EHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPE 119 Query: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHD--TSLPHCRFYEEFDAHGREVPLPAGIYNLD 178 V+ R G VD KC +T + + + D ++ C ++E E LP G+++ + Sbjct: 120 VSKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFE 179 Query: 179 DLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHN 238 L + CPYF+ R I N+++YSYHYLLDPKIA+ VS E+++ ++V+FDEAHN Sbjct: 180 KLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHN 239 Query: 239 IDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAA 298 IDNVCI+S+S++LT L R L + + +++ D Q+L+DEY +LV+GL Sbjct: 240 IDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLXXXXXX 299 Query: 299 RETDAHLANPVLPDEVLQEAVPGSIRT-AEHFLGFLRRLLEYVKWRLRVQHVVQESPPAF 357 AEHF+ FL+RL+EY+K R++V HV+ E+P +F Sbjct: 300 XXXXXXXXXXXXXXXXXXXXXXXXXXXRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSF 359 Query: 358 LSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTII 417 L L Q I+RKPLRFC+ERL L+ TLE+T++ DF+ L +A FATL+STY +GF +I Sbjct: 360 LQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLI 419 Query: 418 IEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVT 477 IEP++ + NPI+ F+C+DAS+AIKPVFERF SVIITSGT+SPLD+YP++L+F V Sbjct: 420 IEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVL 479 Query: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVA 537 ++ MTLA+ PMII +G+DQVAISS+FE R D +++RNYG++L+E + + PDG+V Sbjct: 480 QKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVV 539 Query: 538 FFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILL 597 FF SY YMES V+ W GIL+ + ++KL+ +ET D ETS+ALE Y++AC NGRGAILL Sbjct: 540 FFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILL 599 Query: 598 SVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAM 657 SVARGKVSEGIDF H YGR V+M G+P+ YT+SRILKARLE++R+ ++IRENDFL+FDAM Sbjct: 600 SVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAM 659 Query: 658 RHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVA 717 RHAAQC+GR +RGK DYG+MV AD+RF+R KR +LP+WI + L+DA+LNL+ D + Sbjct: 660 RHAAQCLGRVLRGKDDYGVMVLADRRFSR--KRSQLPKWIAQGLSDADLNLSTDMAISNT 717 Query: 718 KYFLRQMAQPFHREDQLGLSLLSLEQLESEETLKR 752 K FLR MAQP +DQ G+S+ S E L + ++ Sbjct: 718 KQFLRTMAQPTDPKDQEGVSVWSYEDLIKHQNSRK 752 >5H8W-A nrPDB Length = 597 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 139/709 (19%), Positives = 257/709 (36%), Gaps = 131/709 (18%) Query: 35 KGHGV-LEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNF 93 K +GV LE P+G+GKT+ L + Y L K++Y RT + E+VI+ELR L Sbjct: 3 KSYGVALESPTGSGKTIMALKSALQYSSERKL---KVLYLVRTNSQEEQVIKELRSL--- 56 Query: 94 YEKQEGEKLPFLGLALSSRKNLCIH-------PEVTPLRFGKDVDGKCHSLTASYVRAQY 146 + + + R N+CI E+ K + K + A Sbjct: 57 -----SSTMKIRAIPMQGRVNMCILYRMVDDLHEINAESLAKFCNMKKREVMAG------ 105 Query: 147 QHDTSLPHCRFYEEFDAHGR----EVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHA 202 ++ + P+ F D R E+P Y+ G R CPY + ++ A Sbjct: 106 -NEAACPYFNFKIRSDETKRFLFDELPTAEEFYD------YGERNNVCPYESMKAALPDA 158 Query: 203 NVVVYSYHYLLDPKIAD--LVSKELAR-KAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRC 259 ++V+ Y Y L+ +A+ L ++R + V++ DEAHN+ ++ S ++ +L+R Sbjct: 159 DIVIAPYAYFLNRSVAEKFLSHWGVSRNQIVIILDEAHNLPDIGRSIGSFRISVESLNRA 218 Query: 260 QGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREA--SAARETDAHLANPVLPDEVLQE 317 + L Q++ L+E +R A S E + E ++ Sbjct: 219 DREAQAYGDPEL------SQKIH--VSDLIEMIRSALQSMVSERCGKGDVRIRFQEFMEY 270 Query: 318 AVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAE 377 + R+ L L + ++ + V + P ++ S +A R Sbjct: 271 MRIMNKRSEREIRSLLNALYLFGEYVENEKEKVGKVPFSYASSVASR------------- 317 Query: 378 RLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSC 437 I +D +A ++S G+ + + Sbjct: 318 ----------IIAFSD----QDEEKYAAILSPEDGGY------------------MQAAA 345 Query: 438 MDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGR 497 +D S ++ + E I SGTL P D Y I F + Sbjct: 346 LDPSGILEVLKE--SKTIHMSGTLDPFDFYSDITGFEIPFKKIGEIFPPENRYI------ 397 Query: 498 GNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGI 557 +SSK++T D + ++ ++ V + +F SY M+ Sbjct: 398 -AYYDGVSSKYDTL-DEKELDRMATVIEDIILKVKKNTIVYFPSYSLMDRVE-------- 447 Query: 558 LENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRA 617 + + D E L+K++ + +V+ G++SEGI+F + Sbjct: 448 -NRVSFEHMKEYRGIDQKELYSMLKKFRR-----DHGTIFAVSGGRLSEGINFPGNELEM 501 Query: 618 VIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLM 677 +I+ G+P+ I ++ +Y ++ + + Q +GR IR D G Sbjct: 502 IILAGLPFPRP-DAINRSLFDYYCRKYGKGWEYSVVYPTAIKIRQEIGRLIRSAEDTGAA 560 Query: 678 VFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQ 726 V DKR G+ ++I ++ T D + +F+ A+ Sbjct: 561 VILDKR------AGQFRKFI------PDMKKTSDPASDIYNFFISAQAR 597 >2VL7-A nrPDB Length = 540 Score = 207 bits (527), Expect = 1e-53, Method: Composition-based stats. Identities = 46/211 (21%), Positives = 86/211 (40%), Gaps = 20/211 (9%) Query: 477 TMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIV 536 + T+T + + GRG + E R+ + I Y LL + ++ Sbjct: 329 LPESLTLTNSYKIVVNESYGRGEYYYCPNVTSELRKRNSNIPIYSILLKRIYENSSKSVL 388 Query: 537 AFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAIL 596 FF SY+ +ES ++E ++ + E+ E + G+ ++ Sbjct: 389 VFFPSYEMLESVRIHLSGIPVIEENKKTRH---------------EEVLELMKTGKYLVM 433 Query: 597 LSVARGKVSEGIDFVHHYG--RAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTF 654 L V R K SEG++F ++++ G+PY +++ R+E L + ++ D + Sbjct: 434 L-VMRAKESEGVEFREKENLFESLVLAGLPYPNVSDDMVRKRIERL-SKLTGKDEDSIIH 491 Query: 655 DAMRHA-AQCVGRAIRGKTDYGLMVFADKRF 684 D Q +GRA R DY + D R+ Sbjct: 492 DLTAIVIKQTIGRAFRDPNDYVKIYLCDSRY 522 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 37/226 (16%), Positives = 82/226 (36%), Gaps = 32/226 (14%) Query: 83 VIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV 142 ++ + LL + G+ + L + +K + I + K L ++ Sbjct: 22 ALKHGKTLLLNAKPGLGKTVFVEVLGMQLKKKVLIFTRTHSQLDSIYKNAKLLGLKTGFL 81 Query: 143 RAQYQ-----------HDTSLPHCRFYEEFDAHGREVP--LPAGIYNLDDLKALGRRQGW 189 + + + CR ++ + P L + D + Sbjct: 82 IGKSASCIYAQGDEEPDEINCSKCRLKDKIKTIEDKEPSKLIEEFKDAVD---------Y 132 Query: 190 CPYFLARYSILHANVVVYSYHYLLDPKIADLV-----SKELARKAVVVFDEAHNIDNVCI 244 CPY+ R ++ +V+ +Y YL I + V ++V DEAHN+ Sbjct: 133 CPYYSLRANLKDKDVIAMTYPYLFQKPIRNSVFCNKDDCLKLEDYLIVIDEAHNLLEAD- 191 Query: 245 DSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVE 290 + ++R+ L+R +E ++ R+ D ++++D L++ Sbjct: 192 KWFTRKISRKMLERALKEIEIVE----RLNRIDAKKVKDYINLLID 233 >3CRV-A nrPDB Length = 551 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 36/242 (14%) Query: 453 SVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQ--VAISSKFET 510 S+I+ SGTL P + K+ + + G V ++SK++ Sbjct: 317 SIILMSGTLPPREYMEKVWGIK----RNMLYLDVEREIQKRVSGSYECYIGVDVTSKYDM 372 Query: 511 REDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIE 570 R D + + Y + LL++ ++ F SY+ M+ ++ I K ++E Sbjct: 373 RSD-NMWKRYADYLLKIYFQAKANVLVVFPSYEIMDR---------VMSRISLPK--YVE 420 Query: 571 TQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRA----VIMFGVPYV 626 ++D + +E A ++ SV +GK++EGI+ ++ R+ V++ G+PY Sbjct: 421 SEDSS-----VEDLYSAISANNKVLIGSVGKGKLAEGIELRNN-DRSLISDVVIVGIPYP 474 Query: 627 YTQS--RILKARLEYLRDQFQIRENDFLTFD--AMRHAAQCVGRAIRGKTDYGLMVFADK 682 +IL R+ + REN+ F A+ Q +GRAIR D + DK Sbjct: 475 PPDDYLKILAQRVSLKMN----RENEEFLFKIPALVTIKQAIGRAIRDVNDKCNVWLLDK 530 Query: 683 RF 684 RF Sbjct: 531 RF 532 Score = 157 bits (397), Expect = 2e-38, Method: Composition-based stats. Identities = 59/279 (21%), Positives = 103/279 (36%), Gaps = 58/279 (20%) Query: 40 LEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEG 99 L P+G+GKT+ L + + + K+++ RT E + +L K+ Sbjct: 27 LNAPTGSGKTLFSLLVSLEVK-------PKVLFVVRTHNEFYPIYRDLTKIREKRNITFS 79 Query: 100 EKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYE 159 L + + C++ E D +C Sbjct: 80 F--------LVGKPSSCLYAEKGAES----------------------EDIPCKYCELKG 109 Query: 160 EFDAHGREV-PLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIA 218 + PL + LK G + +CPY+ S+ A+V+ +Y Y + Sbjct: 110 SIVEVKTDDSPLSL----VKKLKKDGLQDKFCPYYSLLNSLYKADVIALTYPYFFIDRYR 165 Query: 219 DLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDE 278 + + +L R+ ++V DEAHN+D V L R+L T+Q + IK++ Sbjct: 166 EFIDIDL-REYMIVIDEAHNLDKVN------ELEERSLSEI-----TIQ---MAIKQSKS 210 Query: 279 QRLRDEYRRLVEGLREASAARETDAHLAN-PVLPDEVLQ 316 + R +L+ LRE E + N P L E L+ Sbjct: 211 EESRRILSKLLNQLREVVLPDEKYIKVENVPKLSKEELE 249 >6FWS-A nrPDB Length = 716 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 47/246 (19%), Positives = 94/246 (38%), Gaps = 18/246 (7%) Query: 21 QFSYMRELKRTL--DAKGHGVLEMPSGTGKTVSLLALIMAYQRAYP---------LEVTK 69 Q + ++ +TL + H +E P+G GKT+S L +A R + + Sbjct: 31 QRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQD 90 Query: 70 LIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD 129 IY S+ +P ++K+I +L+ F + LA + + + + Sbjct: 91 QIY-SKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNN 149 Query: 130 VDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGW 189 + + Y+ D H + D R + L Sbjct: 150 QEEQKRCAKLKGDLDTYKWDGLRDHTDIAID-DDLWRRLSTDKA----SCLNRNCYYYRE 204 Query: 190 CPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSV 249 CP+F+AR I A VVV ++ ++ ++ V + + ++V DE H++ +V D++ + Sbjct: 205 CPFFVARREIQEAEVVVANHALVMAAMESEAVLPD-PKNLLLVLDEGHHLPDVARDALEM 263 Query: 250 NLTRRT 255 + Sbjct: 264 SAEITA 269 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 43/233 (18%), Positives = 83/233 (35%), Gaps = 17/233 (7%) Query: 454 VIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFE--TR 511 +I+TS TL L+ + ++ + + +A P V + E Sbjct: 455 IIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDS--PFNHCEQGKIVIPRMRVEPSID 512 Query: 512 EDIAVIRNYGNLLLEMSAVVPD-GIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIE 570 + I E G++ F S + M+ L+ + +L+ + Sbjct: 513 NEEQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQR---------FLDYVTDLRLMLLV 563 Query: 571 TQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQS 630 D + +E +++ NG ++L V +EG+D V + + + S Sbjct: 564 QGDQPRYRL-VELHRKRVANGERSVL--VGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDS 620 Query: 631 RILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKR 683 ++ E+L+ + A + Q VGR IR +G +V DKR Sbjct: 621 PVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKR 673 >4JLV-A nrPDB Length = 269 Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 29/86 (33%), Gaps = 5/86 (5%) Query: 589 ENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRE 648 +N G L + R +SE I ++ G I R + L D F R Sbjct: 133 QNNNGLSSLIIGRTTMSEAITSTEIENLDLLTAGPVPPNPSELIGSERFKELVDLFNKR- 191 Query: 649 NDFLTFDA----MRHAAQCVGRAIRG 670 D + D AQ RAI+ Sbjct: 192 YDIIIVDTPPVNTVTDAQLYARAIKD 217 >2WJV-A nrPDB Length = 800 Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 55/140 (39%), Gaps = 18/140 (12%) Query: 30 RTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELR- 88 +T+ + +++ P GTGKTV+ + + Y A ++ C+ + ++++ E++ Sbjct: 366 KTVLQRPLSLIQGPPGTGKTVT--SATIVYHLARQ-GNGPVLVCAPSNIAVDQLTEKIHQ 422 Query: 89 ------KLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD-------VDGKCH 135 +L + + FL L R N+ PE+ L+ KD D K + Sbjct: 423 TGLKVVRLCAKSREAIDSPVSFLALHNQIR-NMDSMPELQKLQQLKDETGELSSADEKRY 481 Query: 136 SLTASYVRAQYQHDTSLPHC 155 + + + C Sbjct: 482 RALKRTAERELLMNADVICC 501 >5BN5-A nrPDB Length = 570 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 38/191 (19%), Positives = 67/191 (35%), Gaps = 23/191 (12%) Query: 9 LVYFPYDYIYPEQFSY-------MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQR 61 + P Y ++Y + ++ + G + P G+GKTV + Q Sbjct: 183 PIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTV------LNQQI 236 Query: 62 AYPLEVTKLIY--CSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHP 119 A + +IY C E+ +V+EE KL + G+ L + + +++ N+ I Sbjct: 237 AKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKT---GKPLMYRTILIANTSNMPIAA 293 Query: 120 EVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGI--YNL 177 + G + S V D++ E + E+P G Y L Sbjct: 294 REASIYLGATIGEYFRDQGYSVV---VNADSTSRWAEALREISSRLGEIPSEEGYPAYLL 350 Query: 178 DDLKALGRRQG 188 L R G Sbjct: 351 RKLAEFYERSG 361 >4UXV-A nrPDB Length = 545 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 46/281 (16%), Positives = 95/281 (33%), Gaps = 31/281 (11%) Query: 78 PEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPL---RFGKDVDGKC 134 IEK++ E+ L+ EK E SRKNL + + KD+D Sbjct: 100 SSIEKILREISDLVTSEEKSREEIEQVRERYSKSRKNLLAYSHLYGELYDSLEKDLD--- 156 Query: 135 HSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFL 194 + + + + + + + L + I ++ L A ++ P + Sbjct: 157 -EIWSGIKQFEEETEGGNYITARKVLLEQDRNLERLQSYIDDVPKLLADCKQT--VPGQI 213 Query: 195 ARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRR 254 A+ L ++ K + + + E N+ N + V +T Sbjct: 214 AK----------------LKDGYGEMKEKGYKLEHIQLDKELENLSNQLKRAEHVLMTEL 257 Query: 255 TLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEV 314 +D L+ + + + + + E + L + A + + E+ Sbjct: 258 DIDEASAILQLIDENIQSVYQQLEGEVEAGQSVLSKMPELIIAYDKLKEEKEHTKAETEL 317 Query: 315 LQEAVP------GSIRTAEHFLGFLRRLLEYVKWRLRVQHV 349 ++E+ G + E L + +LL VK +L +HV Sbjct: 318 VKESYRLTAGELGKQQAFEKRLDEIGKLLSSVKDKLDAEHV 358 >6EJ5-A nrPDB Length = 637 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 55/140 (39%), Gaps = 18/140 (12%) Query: 30 RTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELR- 88 +T+ + +++ P GTGKTV+ + + Y A ++ C+ + ++++ E++ Sbjct: 203 KTVLQRPLSLIQGPPGTGKTVT--SATIVYHLARQ-GNGPVLVCAPSNIAVDQLTEKIHQ 259 Query: 89 ------KLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKD-------VDGKCH 135 +L + + FL L R N+ PE+ L+ KD D K + Sbjct: 260 TGLKVVRLCAKSREAIDSPVSFLALHNQIR-NMDSMPELQKLQQLKDETGELSSADEKRY 318 Query: 136 SLTASYVRAQYQHDTSLPHC 155 + + + C Sbjct: 319 RALKRTAERELLMNADVICC 338 >4U5I-A nrPDB Length = 403 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 11/68 (16%) Query: 175 YNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLD----PKIADLVSKELARKAV 230 Y DD KA G Y R + N + +Y Y +D ++ +V L+R V Sbjct: 110 YYFDDFKAAG-------YKNVRIPVRWDNHTMRTYPYTIDKAFLDRVEQVVDWSLSRGFV 162 Query: 231 VVFDEAHN 238 + + H+ Sbjct: 163 TIINSHHD 170 >2XZL-A nrPDB Length = 802 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 41/95 (43%), Gaps = 8/95 (8%) Query: 38 GVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKL-LNFYEK 96 +++ P GTGKTV+ + + Y + + +++ C+ + ++ + +LR L L Sbjct: 378 SLIQGPPGTGKTVT--SATIVYHLS-KIHKDRILVCAPSNVAVDHLAAKLRDLGLKVVRL 434 Query: 97 QEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVD 131 + SS NL +H V G+ + Sbjct: 435 TAKSREDVE----SSVSNLALHNLVGRGAKGELKN 465 >2ONJ-A nrPDB Length = 578 Score = 29.7 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 14/109 (12%) Query: 331 GFLRRLLEYVKWR---LRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLE 387 FL R L++ +W + V + P + G+ + I L + + LE Sbjct: 232 NFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGS---ITVGTLAAFVGYLE 288 Query: 388 ITDLADFSPLT-LLANFATLVSTYA---KGFTIIIEPFDDRTPTIANPI 432 + F PL L+A+F TL ++A + F +I E +D + A PI Sbjct: 289 LL----FGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPI 333 >3H1T-A nrPDB Length = 590 Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 22/50 (44%) Query: 14 YDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAY 63 Y Y +Q + R ++ L K ++ M +GTGKTV + A Sbjct: 177 YSPRYYQQIAINRAVQSVLQGKKRSLITMATGTGKTVVAFQISWKLWSAR 226 >3L4G-A nrPDB Length = 508 Score = 28.9 bits (63), Expect = 7.6, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 4/57 (7%) Query: 9 LVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLE----MPSGTGKTVSLLALIMAYQR 61 Y PY E FSY + LK+ ++ GV +P G + VS++A ++ +R Sbjct: 407 PAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLER 463 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.130 0.341 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,685,901 Number of Sequences: 36641 Number of extensions: 1038537 Number of successful extensions: 3163 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 3088 Number of HSP's gapped (non-prelim): 55 length of query: 760 length of database: 10,336,785 effective HSP length: 105 effective length of query: 655 effective length of database: 6,489,480 effective search space: 4250609400 effective search space used: 4250609400 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)