BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P18064 (383 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2XTZ-A nrPDB 718 0.0 3V00-C nrPDB 239 2e-63 2GTP-A nrPDB 234 3e-62 2ODE-A nrPDB 233 8e-62 6D9H-A nrPDB 226 2e-59 1TAG-A nrPDB 224 4e-59 6OIK-A nrPDB 223 1e-58 4QJ3-A nrPDB 215 2e-56 1SHZ-A nrPDB 213 1e-55 2BCJ-Q nrPDB 213 1e-55 6OIJ-A nrPDB 209 2e-54 1ZCB-A nrPDB 176 2e-44 1ZCA-A nrPDB 175 3e-44 4FID-A nrPDB 169 2e-42 5VAI-A nrPDB 162 3e-40 6G79-A nrPDB 107 1e-23 6GDG-D nrPDB 70 1e-12 3AQ4-A nrPDB 38 0.006 3LVQ-E nrPDB 37 0.015 1F6B-A nrPDB 36 0.023 5NZV-F nrPDB 36 0.027 2H57-A nrPDB 36 0.028 2A5F-A nrPDB 35 0.037 3O47-A nrPDB 35 0.077 6FAE-B nrPDB 34 0.086 2B6H-A nrPDB 34 0.11 4YLG-A nrPDB 34 0.12 2GAO-A nrPDB 33 0.17 6BBQ-A nrPDB 33 0.23 5UF8-A nrPDB 33 0.29 1Z6X-A nrPDB 33 0.30 4BAS-A nrPDB 32 0.50 6DFF-C nrPDB 32 0.66 3LRP-A nrPDB 31 0.71 1J2J-A nrPDB 31 0.71 1KSG-A nrPDB 30 1.3 3NUA-A nrPDB 30 1.6 4V0N-A nrPDB 30 1.6 1MOZ-A nrPDB 30 2.1 2X77-A nrPDB 29 3.2 4ILE-A nrPDB 29 4.1 6GNI-B nrPDB 28 4.5 5DE3-A nrPDB 28 5.6 1M2O-B nrPDB 28 7.3 4WNR-A nrPDB 28 7.7 5DI3-B nrPDB 28 8.3 4M9Q-A nrPDB 28 8.7 4ZI3-A nrPDB 28 9.6 >2XTZ-A nrPDB Length = 354 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/347 (100%), Positives = 347/347 (100%) Query: 37 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF 96 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF Sbjct: 8 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF 67 Query: 97 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN 156 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN Sbjct: 68 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN 127 Query: 157 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL 216 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL Sbjct: 128 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL 187 Query: 217 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC 276 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC Sbjct: 188 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC 247 Query: 277 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY 336 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY Sbjct: 248 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY 307 Query: 337 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL Sbjct: 308 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 354 >3V00-C nrPDB Length = 356 Score = 239 bits (610), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 139/367 (37%), Positives = 209/367 (56%), Gaps = 24/367 (6%) Query: 17 ENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVP 76 E + E+E++++++A+ + KLLLLGAGESGKSTI KQ+K++ Q + E ++ Sbjct: 14 EEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDPYSLEECLEFIA 73 Query: 77 VIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIA 136 +I+ N Q+I + DSA+ KL + ++ + K+++ Sbjct: 74 IIYGNTLQSILAIVRAMTTLNIQYGDSARQ-------DDARKLMHMADTIEEGTMPKEMS 126 Query: 137 EGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGV 196 + I+ LWKD IQ R +E Q+ D Y + +L+RL Y+PT++DVL +RV+TTG+ Sbjct: 127 DIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI 186 Query: 197 VEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDE 256 +E QFS N +R+FDVGGQR+ER+KWIH FEGVTA+IFC A+S+YD L EDE Sbjct: 187 IETQFSFKDLN------FRMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE 240 Query: 257 QKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSG 316 + NRM E+ LF+ + F TS +LFLNK D+FE+K+ PL +C P +G Sbjct: 241 EMNRMHESMHLFNSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTIC------YPEYAG 294 Query: 317 KQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRN 376 E A ++K +F EL N D V ++ + T A D + VK F V + + + N Sbjct: 295 SNTYEEAGNYIKVQFLEL---NMRRD-VKEIYS-HMTCATDTQNVKFVFDAVTDIIIKEN 349 Query: 377 LLEAGLL 383 L + GL Sbjct: 350 LKDCGLF 356 >2GTP-A nrPDB Length = 323 Score = 234 bits (598), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 135/344 (39%), Positives = 196/344 (56%), Gaps = 24/344 (6%) Query: 40 KLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEFAQN 99 KLLLLGAGESGKSTI KQ+K++ + G+ E E K Y V+++N Q+I + + Sbjct: 4 KLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKID 63 Query: 100 ETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGNELQ 159 DSA+ +L + G + +T ++A I+ LWKD +Q R E Q Sbjct: 64 FGDSAR-------ADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQ 116 Query: 160 VPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDV 219 + D Y + +L R++ NYIPT++DVL RV+TTG+VE F+ + +++FDV Sbjct: 117 LNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLH------FKMFDV 170 Query: 220 GGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEK 279 GGQR+ER+KWIH FEGVTA+IFC A+S+YD L EDE+ NRM E+ +LFD + F Sbjct: 171 GGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD 230 Query: 280 TSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYYQNT 339 TS +LFLNK D+FE+K+ PL +C P +G E A +++ +FE+L N Sbjct: 231 TSIILFLNKKDLFEEKIKKSPLTIC------YPEYAGSNTYEEAAAYIQCQFEDL---NK 281 Query: 340 APDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 D + + T A D K V+ F V + + + NL + GL Sbjct: 282 RKDT--KEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 323 >2ODE-A nrPDB Length = 350 Score = 233 bits (595), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 138/360 (38%), Positives = 210/360 (58%), Gaps = 30/360 (8%) Query: 24 IERRIEQEA-KAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANV 82 I+R + ++ KA K + KLLLLGAGESGKSTI KQ+K++ + G+ E E K Y V+++N Sbjct: 18 IDRNLREDGEKAAKEV-KLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNT 76 Query: 83 YQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETL 142 Q+I + + + + D + + ++ +L + G + +T ++A I+ L Sbjct: 77 IQSIIAI---IRAMGRLKIDFGEAARADDA----RQLFVLAGSAEEGVMTPELAGVIKRL 129 Query: 143 WKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFS 202 W+D +Q +R E Q+ D Y + +L R+S NYIPT++DVL RV+TTG+VE F+ Sbjct: 130 WRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFT 189 Query: 203 PVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMM 262 +++FDVGGQR+ER+KWIH FEGVTA+IFC A+S+YD L EDE+ NRM Sbjct: 190 F------KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMH 243 Query: 263 ETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEH 322 E+ +LFD + F +TS +LFLNK D+FE+K+ PL +C P +G E Sbjct: 244 ESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTIC------YPEYTGSNTYEE 297 Query: 323 AYEFVKKKFEELYYQNTAPDRVDRVFKIYR--TTALDQKLVKKTFKLVDETLRRRNLLEA 380 A +++ +FE+L +R +IY T A D K V+ F V + + + NL E+ Sbjct: 298 AAAYIQCQFEDL-------NRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKES 350 >6D9H-A nrPDB Length = 355 Score = 226 bits (575), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 136/371 (36%), Positives = 207/371 (55%), Gaps = 27/371 (7%) Query: 17 ENTQAAEIERRIEQEAK--AEKHIR--KLLLLGAGESGKSTIFKQIKLLFQTGFDEGELK 72 E+ AAE + I++ + EK R KLLLLGAGESGK+TI KQ+K++ + G+ E E + Sbjct: 8 EDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEDGYSEEECR 67 Query: 73 SYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLT 132 Y V+++N Q+I + + D ++ + + A+ E G L Sbjct: 68 QYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQG------VLP 121 Query: 133 KDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVR 192 D++ I LW D +Q R E Q+ D Y + +L+R++ +YIPT++DVL RV+ Sbjct: 122 DDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVK 181 Query: 193 TTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTL 252 TTG+VE F+ + +++FDVG QR+ER+KWIH FEGVTA+IFC A+S YD L Sbjct: 182 TTGIVETHFTFKDLH------FKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSAYDLVL 235 Query: 253 FEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQP 312 EDE+ NRM + +LFD + F TS +LFLNK D+FE+K+ PL +C F +Y Sbjct: 236 AEDEEMNRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTIC--FPEY-- 291 Query: 313 VSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETL 372 +G + + A +++ KFE+L N D + + T + D K V+ F V + + Sbjct: 292 --TGANKYDEAASYIQSKFEDL---NKRKDT--KEIYTHFTCSTDTKNVQFVFDAVTDVI 344 Query: 373 RRRNLLEAGLL 383 + NL + GL Sbjct: 345 IKNNLKDCGLF 355 >1TAG-A nrPDB Length = 324 Score = 224 bits (572), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 134/344 (38%), Positives = 195/344 (56%), Gaps = 24/344 (6%) Query: 40 KLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEFAQN 99 KLLLLGAGESGKSTI KQ+K++ Q G+ E ++ +I+ N Q+I + Sbjct: 5 KLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQ 64 Query: 100 ETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGNELQ 159 DSA+ KL + ++ + K++++ I+ LWKD IQ R +E Q Sbjct: 65 YGDSARQ-------DDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFDRASEYQ 117 Query: 160 VPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDV 219 + D Y + +L+RL Y+PT++DVL +RV+TTG++E QFS N +R+FDV Sbjct: 118 LNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLN------FRMFDV 171 Query: 220 GGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEK 279 GGQR+ER+KWIH FEGVT +IF AA+S YD L ED++ NRM E+ LF+ + F Sbjct: 172 GGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFAT 231 Query: 280 TSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYYQNT 339 TS +LFLNK D+F +K+ L++C F DY +G E A ++K +F EL N Sbjct: 232 TSIVLFLNKKDVFSEKIKKAHLSIC--FPDY----NGPNTYEDAGNYIKVQFLEL---NM 282 Query: 340 APDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 D V ++ + T A D + VK F V + + + NL + GL Sbjct: 283 RRD-VKEIYS-HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 324 >6OIK-A nrPDB Length = 354 Score = 223 bits (567), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 133/362 (36%), Positives = 200/362 (55%), Gaps = 30/362 (8%) Query: 24 IERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVY 83 IE+ ++++ + KLLLLGAGESGKSTI KQ+K++ + GF ++K Y PV+++N Sbjct: 19 IEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTI 78 Query: 84 QTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRL-DYPRLTKDIAEGIETL 142 Q++ + D E A + + ++ R+ D + ++ + L Sbjct: 79 QSLAAIVRAMDTLGIEYGDK-------ERKADAKMVCDVVSRMEDTEPFSAELLSAMMRL 131 Query: 143 WKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFS 202 W D IQE R E Q+ D KY +++L R+ +Y PT++D+L RV+TTG+VE F+ Sbjct: 132 WGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFT 191 Query: 203 PVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMM 262 + +RLFDVGGQR+ER+KWIH FE VTA+IFC A+S YDQ L EDE NRM Sbjct: 192 FKNLH------FRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245 Query: 263 ETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEH 322 E+ LFD + F TS +LFLNK D+F +K+ PL +C F +Y +G E Sbjct: 246 ESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTIC--FPEY----TGPNTYED 299 Query: 323 AYEFVKKKFEELYYQNTAPDRVDRVFKIY--RTTALDQKLVKKTFKLVDETLRRRNLLEA 380 A +++ +FE +N +P++ +IY T A D ++ F V + + NL Sbjct: 300 AAAYIQAQFES---KNRSPNK-----EIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGC 351 Query: 381 GL 382 GL Sbjct: 352 GL 353 >4QJ3-A nrPDB Length = 379 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 131/365 (35%), Positives = 206/365 (56%), Gaps = 33/365 (9%) Query: 23 EIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANV 82 EIER++ ++ + + KLLLLG GESGKST KQ++++ +G+ + + + + +++ N+ Sbjct: 44 EIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNI 103 Query: 83 YQTIKLL---HDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGI 139 + ++ + D K + E + A L E EK+S + I Sbjct: 104 FTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDV--EKVSA---------FENPYVDAI 152 Query: 140 ETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEI 199 ++LW DP IQE R E Q+ D TKY + +L R++D +Y+PT++DVL RV TTG++E Sbjct: 153 KSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEY 212 Query: 200 QFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKN 259 F ++R+ DVGGQR+ERRKWIH FE VT+++F A+SEYDQ L E + +N Sbjct: 213 PFD------LQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN 266 Query: 260 RMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQ- 318 RM E+K LF ++ P F+ +S +LFLNK D+ E+K++ L DY P G Q Sbjct: 267 RMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL------VDYFPEYDGPQR 320 Query: 319 EIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLL 378 + + A EF+ K F +L PD D++ + T A D + ++ F V +T+ + NL Sbjct: 321 DAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFVFAAVKDTILQLNLK 374 Query: 379 EAGLL 383 E L+ Sbjct: 375 EYNLV 379 >1SHZ-A nrPDB Length = 340 Score = 213 bits (542), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 126/355 (35%), Positives = 193/355 (54%), Gaps = 18/355 (5%) Query: 29 EQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKL 88 E KA + + KLLLLGAGESGKST KQ++++ FD+ + + P I++NV + +++ Sbjct: 4 EDGEKAAREV-KLLLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRV 62 Query: 89 LHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAI 148 L D ++ D+ + + +A + + R+ I LW+D I Sbjct: 63 LVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWEDSGI 122 Query: 149 QETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENK 208 Q R E Q+ + KY ++NL +L +YIP+++D+L AR T G+ E F+ + Sbjct: 123 QNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHETHFTFKDLH- 181 Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 +++FDVGGQR+ER+KW FEGVTA+IFC A+S+YDQ L ED Q NRM E+ +LF Sbjct: 182 -----FKMFDVGGQRSERKKWFECFEGVTAIIFCVALSDYDQVLMEDRQTNRMHESMKLF 236 Query: 269 DWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVK 328 D + F TS +LFLNK D+FE+K+ PL +C P +G E A +++ Sbjct: 237 DSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTIC------YPEYAGSNTYEEAAAYIQ 290 Query: 329 KKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 +FE+L N D + + T A D K V+ F V + + + NL + GL Sbjct: 291 CQFEDL---NKRKDT--KEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 340 >2BCJ-Q nrPDB Length = 353 Score = 213 bits (541), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 131/376 (34%), Positives = 208/376 (55%), Gaps = 33/376 (8%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + KLLLLG GESGKST KQ++++ +G+ + + Sbjct: 7 AEDKAAVERSKMIDRNLREDGERSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDK 66 Query: 72 KSYVPVIHANVYQTIKLL---HDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDY 128 + + +++ N++ ++ + D K + E + A L E EK+S Sbjct: 67 RGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDV--EKVSA------- 117 Query: 129 PRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLY 188 + I++LW DP IQE R E Q+ D TKY + +L R++D +Y+PT++DVL Sbjct: 118 --FENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLR 175 Query: 189 ARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEY 248 RV TTG++E F ++R+ DVGGQR+ERRKWIH FE VT+++F A+SEY Sbjct: 176 VRVPTTGIIEYPFD------LQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEY 229 Query: 249 DQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFR 308 DQ L E + +NRM E+K LF ++ P F+ +S +LFLNK D+ E+K++ L Sbjct: 230 DQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL------V 283 Query: 309 DYQPVSSGKQ-EIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKL 367 DY P G Q + + A EF+ K F +L PD D++ + T A D + ++ F Sbjct: 284 DYFPEYDGPQRDAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFVFAA 337 Query: 368 VDETLRRRNLLEAGLL 383 V +T+ + NL E L+ Sbjct: 338 VKDTILQLNLKEYNLV 353 >6OIJ-A nrPDB Length = 353 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 131/379 (34%), Positives = 208/379 (54%), Gaps = 39/379 (10%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + KLLLLG GESGKST KQ++++ G+ E + Sbjct: 7 AEDKAAVERSKMIDRNLREDGEKARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDK 66 Query: 72 KSYVPVIHANVYQTIKLL---HDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDY 128 + + +++ N++ ++ + + K + E + A +L E +D Sbjct: 67 RGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIRE--------------VDV 112 Query: 129 PRLT---KDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKED 185 ++T I+TLW+DP IQE R E Q+ D KY + ++ R++ + Y+PT++D Sbjct: 113 EKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQD 172 Query: 186 VLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAI 245 VL RV TTG++E F EN ++R+ DVGGQR+ERRKWIH FE VT+++F A+ Sbjct: 173 VLRVRVPTTGIIEYPFDL--ENI----IFRMVDVGGQRSERRKWIHCFENVTSIMFLVAL 226 Query: 246 SEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCE 305 SEYDQ L E + +NRM E+K LF ++ P F+ +S +LFLNK D+ E K+L L Sbjct: 227 SEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHL---- 282 Query: 306 WFRDYQPVSSGKQ-EIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKT 364 DY P G Q + + A EF+ K F +L PD D++ + T A D + ++ Sbjct: 283 --VDYFPEFDGPQRDAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFV 334 Query: 365 FKLVDETLRRRNLLEAGLL 383 F V +T+ + NL E L+ Sbjct: 335 FAAVKDTILQLNLKEYNLV 353 >1ZCB-A nrPDB Length = 362 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 105/366 (28%), Positives = 193/366 (52%), Gaps = 16/366 (4%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + K+LLLGAGESGKST KQ++++ FD+ Sbjct: 7 AEDKAAVERSKMIDRNLREDGERSARLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 66 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRL 131 + + P I++NV + +++L D ++ D+ + + +A + + R+ Sbjct: 67 EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRV 126 Query: 132 TKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARV 191 I LW+D IQ R E Q+ + KY ++NL +L +YIP+++D+L AR Sbjct: 127 FLQYLPAIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARR 186 Query: 192 RTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQT 251 T G+ E F + +++ DVGGQR+ER++W F+ VT+++F + SE+DQ Sbjct: 187 PTKGIHEYDF------EIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQV 240 Query: 252 LFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQ 311 L ED Q NR+ E+ +F+ ++ F S +LFLNK D+ E+KV V ++ ++F +++ Sbjct: 241 LMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQVV--SIKDYFLEFE 298 Query: 312 PVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDET 371 ++++ KF ++ D+ R + TTA++ + ++ F+ V +T Sbjct: 299 GDPHCLRDVQ--------KFLVECFRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDT 350 Query: 372 LRRRNL 377 + NL Sbjct: 351 ILHDNL 356 >1ZCA-A nrPDB Length = 359 Score = 175 bits (444), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 115/374 (30%), Positives = 202/374 (54%), Gaps = 35/374 (9%) Query: 12 TEDTDENTQAAEIERRIEQ--EAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEG 69 ED ++ I+R + + E +A + + K+LLLGAGESGKST KQ++++ FD+ Sbjct: 7 AEDKAAVERSKMIDRNLREDGERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQK 66 Query: 70 ELKSYVPVIHANVYQTIKLLHDGTKEF------AQNETDSAKYMLSSESIAIGEKLSEIG 123 L + I N+ + ++L D + ++NE ++++ E+ A G + Sbjct: 67 ALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEK-HGMFLMAFENKA-GLPVEPAT 124 Query: 124 GRLDYPRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTK 183 +L P L+ LW+D I+E +R +E Q+ + KY ++NL R+ +NY P+K Sbjct: 125 FQLYVPALS--------ALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSK 176 Query: 184 EDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCA 243 +D+L AR T G+VE F KK +++ DVGGQR++R+KW F+G+T+++F Sbjct: 177 QDILLARKATKGIVEHDFVI----KKIP--FKMVDVGGQRSQRQKWFQCFDGITSILFMV 230 Query: 244 AISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNV 303 + SEYDQ L ED + NR++E+ +F+ ++ F S +LFLNK D+ +KV V ++ Sbjct: 231 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSV--SI 288 Query: 304 CEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKK 363 + F D++ +E ++ + F+ + P +F + TTA+D + ++ Sbjct: 289 KKHFPDFK---GDPHRLEDVQRYLVQCFDRKRRNRSKP-----LFHHF-TTAIDTENIRF 339 Query: 364 TFKLVDETLRRRNL 377 F V +T+ + NL Sbjct: 340 VFHAVKDTILQENL 353 >4FID-A nrPDB Length = 340 Score = 169 bits (428), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 96/263 (36%), Positives = 147/263 (55%), Gaps = 20/263 (7%) Query: 41 LLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEFAQNE 100 ++LLG+GESGKSTI KQ+K+LF GF E E ++ I +NV ++ L + + Sbjct: 8 VMLLGSGESGKSTIAKQLKILFGGGFPEQERATHKSSICSNVVTCMRTLIEQSAILNH-- 65 Query: 101 TDSAKYMLSSESIAIGEKLSEIGGRLDY-PRLTKDIAEGIETLWKDPAIQETCARGNELQ 159 KY S+ + ++ L + P L D+ E LW D IQ T + Q Sbjct: 66 --PMKYQPKSKEFTTEDPVT-----LPFSPELVGDV----EALWADEGIQATYEESAKFQ 114 Query: 160 VPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDV 219 +PDC KYL EN+KR++ +Y+PT+ED+++ R +TTG+ E F + L DV Sbjct: 115 LPDCAKYLFENVKRIAMEDYVPTEEDLIHNRTKTTGIHEYDFV------VKDIPFHLIDV 168 Query: 220 GGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEK 279 GGQR+ER+KW+ F V IF +++EYD L+ED +R+ E+ +F ++ + Sbjct: 169 GGQRSERKKWVSFFSDVDCAIFVTSLAEYDMKLYEDGNTSRLTESIAVFKDIMTNEFLKG 228 Query: 280 TSFMLFLNKFDIFEKKVLDVPLN 302 ++FLNK D+FE+K+ VPLN Sbjct: 229 AVKLIFLNKMDLFEEKLTKVPLN 251 >5VAI-A nrPDB Length = 380 Score = 162 bits (409), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 112/378 (29%), Positives = 186/378 (49%), Gaps = 39/378 (10%) Query: 23 EIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFD-EGELKSYVPVIHAN 81 +IE++++++ + + +LLLLGAGESGKSTI KQ+++L GF+ + E + V I N Sbjct: 25 KIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNN 84 Query: 82 VYQTIKLLHDGTK------EFAQNETD-SAKYMLSSESIAIGEKLSEIGGRLDYPRLTKD 134 + + I+ + E A E Y+LS ++ D+P + Sbjct: 85 LKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVP----------DFDFP---PE 131 Query: 135 IAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTT 194 E + LW+D ++ R NE Q+ DC +Y ++ + + +Y+P+ +D+L RV T+ Sbjct: 132 FYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTS 191 Query: 195 GVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFE 254 G+ E +F N + +FDVGGQR+ERRKWI F VTA+IF A S Y+ + E Sbjct: 192 GIFETKFQVDKVN------FHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIRE 245 Query: 255 DEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWF------- 307 D Q NR+ E LF + S +LFLNK D+ +KVL + ++F Sbjct: 246 DNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYT 305 Query: 308 --RDYQPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTF 365 D P + A F++ +F + +TA + T A+D + +++ F Sbjct: 306 TPEDATPEPGEDPRVTRAKYFIRDEFLRI---STASGDGRHYCYPHFTCAVDTENIRRVF 362 Query: 366 KLVDETLRRRNLLEAGLL 383 + ++R +L + LL Sbjct: 363 NDCRDIIQRMHLRQYELL 380 >6G79-A nrPDB Length = 225 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 66/171 (38%), Positives = 93/171 (54%), Gaps = 26/171 (15%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 +RLFDVGGQR+ER+KWIH FE VTA+IFC +S+Y NRM E+ LFD + Sbjct: 78 FRLFDVGGQRSERKKWIHCFEDVTAIIFCVDLSDY----------NRMHESLMLFDSICN 127 Query: 274 QPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEE 333 F TS +LFLNK D+F +K+ PL +C F +Y +G E A +++ +FE Sbjct: 128 NKFFIDTSIILFLNKKDLFGEKIKKSPLTIC--FPEY----TGPNTYEDAAAYIQAQFES 181 Query: 334 LYYQNTAPDRVDRVFKIY--RTTALDQKLVKKTFKLVDETLRRRNLLEAGL 382 +N +P++ +IY T A D + F V + + NL GL Sbjct: 182 ---KNRSPNK-----EIYCHMTCATDTNNAQVIFDAVTDIIIANNLRGCGL 224 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 29/42 (69%) Query: 20 QAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLL 61 ++ IE+ ++++ + KLLLLGA SGKSTI KQ+K++ Sbjct: 12 RSKAIEKNLKEDGISAAKDVKLLLLGADNSGKSTIVKQMKII 53 >6GDG-D nrPDB Length = 248 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 22/179 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + +FDVGGQR+ERRKWI F VTA+IF S+Y NR+ E LF + Sbjct: 83 FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDY----------NRLQEALNLFKSIWN 132 Query: 274 QPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWF---------RDYQPVSSGKQEIEHAY 324 S +LFLNK D+ +KVL + ++F D P + A Sbjct: 133 NRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAK 192 Query: 325 EFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 F++ +F + +TA + T A+D + ++ F + ++R +L + LL Sbjct: 193 YFIRDEFLRI---STASGDGRHYCYPHFTCAVDTENARRIFNDCRDIIQRMHLRQYELL 248 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 30/39 (76%) Query: 23 EIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLL 61 +IE++++++ + + +LLLLGA SGKSTI KQ+++L Sbjct: 20 KIEKQLQKDKQVYRATHRLLLLGADNSGKSTIVKQMRIL 58 >3AQ4-A nrPDB Length = 184 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H F+ +IF ++ D+ + ++ +RM+ EL D VL Sbjct: 66 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVL- 124 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 125 ---------LVFANKQDL 133 >3LVQ-E nrPDB Length = 497 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H + G +IF ++ D+ ++ +R++ +E+ D ++ Sbjct: 368 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII- 426 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 427 ---------LIFANKQDL 435 >1F6B-A nrPDB Length = 198 Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust. Identities = 17/81 (20%), Positives = 35/81 (43%), Gaps = 10/81 (12%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 +G + FD+GG RR W + + ++F ++++ R++E+KE D Sbjct: 67 AGMTFTTFDLGGHIQARRVWKNYLPAINGIVFLVDCADHE----------RLLESKEELD 116 Query: 270 WVLKQPCFEKTSFMLFLNKFD 290 ++ ++ NK D Sbjct: 117 SLMTDETIANVPILILGNKID 137 >5NZV-F nrPDB Length = 181 Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H + VIF + ++R+ E +E+ +L Sbjct: 63 FTVWDVGGQDRIRSLWRHYYRNTEGVIFVV----------DSNDRSRIGEAREVMQRMLN 112 Query: 274 QPCFEKTSFMLFLNKFDIFE 293 + ++++F NK D+ E Sbjct: 113 EDELRNAAWLVFANKQDLPE 132 >2H57-A nrPDB Length = 190 Score = 36.2 bits (82), Expect = 0.028, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 12/86 (13%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 K S + +FD+ GQ R W H ++ A+IF + + + RM+ KE Sbjct: 63 KSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIF----------VIDSSDRLRMVVAKEE 112 Query: 268 FDWVLKQPCFE--KTSFMLFLNKFDI 291 D +L P + + + F NK D+ Sbjct: 113 LDTLLNHPDIKHRRIPILFFANKMDL 138 >2A5F-A nrPDB Length = 175 Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H + G +IF ++ D+ ++ +R++ +E+ D ++ Sbjct: 59 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII- 117 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 118 ---------LIFANKQDL 126 >3O47-A nrPDB Length = 329 Score = 34.7 bits (78), Expect = 0.077, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H F+ +IF ++ ++ E+ RM+ EL D VL Sbjct: 211 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVL- 269 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 270 ---------LVFANKQDL 278 >6FAE-B nrPDB Length = 213 Score = 34.3 bits (77), Expect = 0.086, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H F+ +IF ++ ++ E+ RM+ EL D VL Sbjct: 95 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVL- 153 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 154 ---------LVFANKQDL 162 >2B6H-A nrPDB Length = 192 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H F+ +IF ++ ++ ++ +M++ EL D VL Sbjct: 75 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVL- 133 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 134 ---------LVFANKQDM 142 >4YLG-A nrPDB Length = 173 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H ++ A+IF + + ++R+ E +E +L Sbjct: 59 FTVWDVGGQDKIRPLWRHYYQNTQAIIF----------VVDSNDRDRIGEAREELMKMLN 108 Query: 274 QPCFEKTSFMLFLNKFDI 291 + ++F NK D+ Sbjct: 109 EDEMRNAILLVFANKHDL 126 >2GAO-A nrPDB Length = 208 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 10/81 (12%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 +G + FD+GG RR W + + ++F +++ +R++E+K + Sbjct: 77 AGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADH----------SRLVESKVELN 126 Query: 270 WVLKQPCFEKTSFMLFLNKFD 290 ++ ++ NK D Sbjct: 127 ALMTDETISNVPILILGNKID 147 >6BBQ-A nrPDB Length = 520 Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust. Identities = 18/78 (23%), Positives = 38/78 (48%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGG R W H + G +IF ++ D+ ++ +R++ +E+ D ++ Sbjct: 405 FNVWDVGGLDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII- 463 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 464 ---------LIFANKQDL 472 >5UF8-A nrPDB Length = 181 Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W + F+ +IF ++ D+ E+ +M+ EL D +L Sbjct: 63 FTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELRDALL- 121 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 122 ---------LVFANKQDL 130 >1Z6X-A nrPDB Length = 180 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H F+ +IF ++ ++ ++ +M+ EL D VL Sbjct: 63 FTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVL- 121 Query: 274 QPCFEKTSFMLFLNKFDI 291 +LF NK D+ Sbjct: 122 ---------LLFANKQDL 130 >4BAS-A nrPDB Length = 199 Score = 32.0 bits (71), Expect = 0.50, Method: Compositional matrix adjust. Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 213 VYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVL 272 + +FD+GG + R W ++ + AVIF S++ + + M++ +++ Sbjct: 64 AFTVFDMGGAKKFRGLWETYYDNIDAVIFVVDSSDHLRLCVVKSEIQAMLKHEDIRR--- 120 Query: 273 KQPCFEKTSFMLFLNKFD 290 + P + F+ F NK D Sbjct: 121 ELPGGGRVPFLFFANKMD 138 >6DFF-C nrPDB Length = 193 Score = 31.6 bits (70), Expect = 0.66, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGG R W H F+ +IF ++ ++ E+ RM+ EL D VL Sbjct: 75 FTVWDVGGLDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVL- 133 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 134 ---------LVFANKQDL 142 >3LRP-A nrPDB Length = 181 Score = 31.2 bits (69), Expect = 0.71, Method: Compositional matrix adjust. Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGGQ R W H + +IF ++ ++ E+ +RM+ +EL D ++ Sbjct: 63 FTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAII- 121 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 122 ---------LVFANKQDL 130 >1J2J-A nrPDB Length = 166 Score = 31.2 bits (69), Expect = 0.71, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++DVGG R W H F+ +IF ++ ++ E+ RM+ EL D VL Sbjct: 48 FTVWDVGGLDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVL- 106 Query: 274 QPCFEKTSFMLFLNKFDI 291 ++F NK D+ Sbjct: 107 ---------LVFANKQDL 115 >1KSG-A nrPDB Length = 186 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 17/76 (22%), Positives = 35/76 (46%), Gaps = 10/76 (13%) Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQP 275 ++DVGGQ++ R W + FE +I+ + + + RM + + +L + Sbjct: 66 IWDVGGQKSLRSYWRNYFESTDGLIW----------VVDSADRQRMQDCQRELQSLLVEE 115 Query: 276 CFEKTSFMLFLNKFDI 291 + ++F NK D+ Sbjct: 116 RLAGATLLIFANKQDL 131 >3NUA-A nrPDB Length = 238 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 32/164 (19%) Query: 232 LFEGVTAVIFCA-----AISEY--DQTLFEDEQKNRMMETKELFDWVLKQPCFE------ 278 L+EG I+ I Y D T F E+K ++ E+K + + + FE Sbjct: 11 LYEGKAKKIYATDKEDMVIVHYKDDATAFNGEKKAQI-ESKGVLNNEITSLIFEMLNKEG 69 Query: 279 -KTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQ-EIEHAYEFVKKKFEELYY 336 KT F+ LN D KKV VPL V R+ S K+ +E YE FE Y Sbjct: 70 IKTHFVEKLNDRDQLCKKVEIVPLEVI--VRNVAAGSMAKRLGLEEGYELKTTVFELSYK 127 Query: 337 QNTAPDRV--------------DRVFKIYRTTALDQKLVKKTFK 366 ++ D + + + KIY TA +++K+ FK Sbjct: 128 DDSLGDPLINDYHAVGIGATTFEELNKIYEITAKVNEILKEAFK 171 >4V0N-A nrPDB Length = 169 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 204 VGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMME 263 V E +K + +FD+ G R W + AV+F + + K RM+ Sbjct: 44 VDEVEKGPLTFTVFDMSGAGRYRTLWEQYYREADAVVF----------VVDSADKLRMVV 93 Query: 264 TKELFDWVLKQPCFEKTSFMLFLNKFDI 291 ++ + +LK K + F NK D+ Sbjct: 94 ARDEMEHMLKHSNMRKVPILYFANKKDL 121 >1MOZ-A nrPDB Length = 183 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 10/76 (13%) Query: 215 RLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQ 274 ++D+GGQ + R W + AVIF ++ D+ ++ + M++ +EL D Sbjct: 65 NVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQD----- 119 Query: 275 PCFEKTSFMLFLNKFD 290 + ++F NK D Sbjct: 120 -----AALLVFANKQD 130 >2X77-A nrPDB Length = 189 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 10/78 (12%) Query: 214 YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLK 273 + ++D+GGQ R W F AVI+ + + ++RM K +L Sbjct: 68 FEVWDLGGQTGVRPYWRCYFSDTDAVIY----------VVDSTDRDRMGVAKHELYALLD 117 Query: 274 QPCFEKTSFMLFLNKFDI 291 + K+ ++F NK D+ Sbjct: 118 EDELRKSLLLIFANKQDL 135 >4ILE-A nrPDB Length = 184 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 10/83 (12%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 K +L+D+GGQ R W GV+A+++ + DQ E KN + Sbjct: 64 KGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVY--MVDAADQEKIE-ASKNELHN----- 115 Query: 269 DWVLKQPCFEKTSFMLFLNKFDI 291 +L +P + ++ NK D+ Sbjct: 116 --LLDKPQLQGIPVLVLGNKRDL 136 >6GNI-B nrPDB Length = 167 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 21/91 (23%), Positives = 33/91 (36%), Gaps = 11/91 (12%) Query: 201 FSPVGENKKSGEV-YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKN 259 + P E G + + FD+GG RR W F V ++F L + Sbjct: 33 WHPTSEELAIGNIKFTTFDLGGHIQARRLWKDYFPEVNGIVF----------LVDAADPE 82 Query: 260 RMMETKELFDWVLKQPCFEKTSFMLFLNKFD 290 R E + D + + F++ NK D Sbjct: 83 RFDEARVELDALFNIAELKDVPFVILGNKID 113 >5DE3-A nrPDB Length = 169 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 17/83 (20%), Positives = 39/83 (46%), Gaps = 10/83 (12%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 + G +++D+GGQ++ R W + F+ A+I+ + + R+ E++ Sbjct: 41 RDGFNLKIWDIGGQKSIRPYWRNYFDQTDALIY----------VIDSADSKRLSESEFEL 90 Query: 269 DWVLKQPCFEKTSFMLFLNKFDI 291 +L++ ++F NK D+ Sbjct: 91 TELLQEEKMTGVPLLVFANKQDL 113 >1M2O-B nrPDB Length = 190 Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Query: 201 FSPVGENKKSGEV-YRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISE---YDQTLFEDE 256 + P E G + + FD+GG RR W F V ++F ++ +D+ E + Sbjct: 55 WHPTSEELAIGNIKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAADPERFDEARVELD 114 Query: 257 QKNRMMETKEL 267 + E K++ Sbjct: 115 ALFNIAELKDV 125 >4WNR-A nrPDB Length = 349 Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 4/45 (8%) Query: 26 RRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGE 70 + +E E K + K+LL+G GE+GK+++ K+ L GFD E Sbjct: 30 KSLEGEKKPLNEV-KVLLVGDGEAGKTSLLKR---LLGEGFDGNE 70 >5DI3-B nrPDB Length = 263 Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQP 275 +FD+GG +N R W V A+++ + D FE E K M E VL+ Sbjct: 52 VFDLGGGKNIRGVWKKYLAEVHAIVYV--VDAADPGRFE-ESKMTMAE-------VLENQ 101 Query: 276 CFEKTSFMLFLNKFDI 291 +F NK D+ Sbjct: 102 FMRDKPICIFANKQDL 117 >4M9Q-A nrPDB Length = 227 Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQP 275 +FD+GG +N R W V A+++ + D FE E K M E VL+ Sbjct: 52 VFDLGGGKNIRGVWKKYLAEVHAIVYV--VDAADPGRFE-ESKMTMAE-------VLENQ 101 Query: 276 CFEKTSFMLFLNKFDI 291 +F NK D+ Sbjct: 102 FMRDKPICIFANKQDL 117 >4ZI3-A nrPDB Length = 190 Score = 27.7 bits (60), Expect = 9.6, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFED 255 ++D+GGQR R W FE +I+ I D+ FE+ Sbjct: 65 VWDIGGQRKIRPYWRSYFENTDILIY--VIDSADRKRFEE 102 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1SHZ-A nrPDB 494 e-140 6D9H-A nrPDB 493 e-140 2ODE-A nrPDB 493 e-140 3V00-C nrPDB 489 e-138 6OIK-A nrPDB 486 e-138 2GTP-A nrPDB 481 e-136 1TAG-A nrPDB 463 e-131 1ZCB-A nrPDB 460 e-130 2BCJ-Q nrPDB 448 e-126 2XTZ-A nrPDB 446 e-126 6OIJ-A nrPDB 444 e-125 4QJ3-A nrPDB 431 e-121 1ZCA-A nrPDB 417 e-117 5VAI-A nrPDB 416 e-117 4FID-A nrPDB 339 1e-93 6G79-A nrPDB 231 3e-61 6GDG-D nrPDB 209 2e-54 Sequences not found previously or not previously below threshold: 3LVQ-E nrPDB 56 3e-08 2A5F-A nrPDB 55 5e-08 3AQ4-A nrPDB 54 9e-08 5NZV-F nrPDB 52 4e-07 5UF8-A nrPDB 51 7e-07 6BBQ-A nrPDB 51 1e-06 3LRP-A nrPDB 50 2e-06 2B6H-A nrPDB 50 2e-06 6FAE-B nrPDB 49 2e-06 3O47-A nrPDB 49 3e-06 4YLG-A nrPDB 49 3e-06 4M9Q-A nrPDB 47 1e-05 5DI3-B nrPDB 47 1e-05 5DE3-A nrPDB 47 1e-05 1KSG-A nrPDB 47 1e-05 2X77-A nrPDB 46 2e-05 1Z6X-A nrPDB 46 3e-05 6DFF-C nrPDB 46 3e-05 1J2J-A nrPDB 45 4e-05 1YZG-A nrPDB 45 4e-05 1F6B-A nrPDB 45 5e-05 2GAO-A nrPDB 45 5e-05 2H57-A nrPDB 45 6e-05 1MOZ-A nrPDB 42 3e-04 4BAS-A nrPDB 42 6e-04 4ZI3-A nrPDB 41 7e-04 2H16-A nrPDB 41 8e-04 4V0N-A nrPDB 41 8e-04 6GNI-B nrPDB 40 0.002 1M2O-B nrPDB 40 0.002 3BH6-A nrPDB 38 0.007 4WNR-A nrPDB 33 0.23 4M8N-E nrPDB 31 0.70 2QGA-B nrPDB 31 0.81 2GWD-A nrPDB 31 1.1 6FKM-A nrPDB 30 1.3 6I3U-A nrPDB 29 5.4 6HLU-A nrPDB 28 7.2 >1SHZ-A nrPDB Length = 340 Score = 494 bits (1271), Expect = e-140, Method: Composition-based stats. Identities = 123/357 (34%), Positives = 192/357 (53%), Gaps = 17/357 (4%) Query: 27 RIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTI 86 + ++ + KLLLLGAGESGKST KQ++++ FD+ + + P I++NV + + Sbjct: 1 NLREDGEKAAREVKLLLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGM 60 Query: 87 KLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDP 146 ++L D ++ D+ + + +A + + R+ I LW+D Sbjct: 61 RVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWEDS 120 Query: 147 AIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGE 206 IQ R E Q+ + KY ++NL +L +YIP+++D+L AR T G+ E F+ Sbjct: 121 GIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHETHFTFKDL 180 Query: 207 NKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKE 266 + +++FDVGGQR+ER+KW FEGVTA+IFC A+S+YDQ L ED Q NRM E+ + Sbjct: 181 H------FKMFDVGGQRSERKKWFECFEGVTAIIFCVALSDYDQVLMEDRQTNRMHESMK 234 Query: 267 LFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEF 326 LFD + F TS +LFLNK D+FE+K+ PL +C P +G E A + Sbjct: 235 LFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTIC------YPEYAGSNTYEEAAAY 288 Query: 327 VKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 ++ +FE+L N D + + T A D K V+ F V + + + NL + GL Sbjct: 289 IQCQFEDL---NKRKDT--KEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 340 >6D9H-A nrPDB Length = 355 Score = 493 bits (1270), Expect = e-140, Method: Composition-based stats. Identities = 128/372 (34%), Positives = 202/372 (54%), Gaps = 23/372 (6%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I++ + ++ + KLLLLGAGESGK+TI KQ+K++ + G+ E E Sbjct: 7 AEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEDGYSEEEC 66 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRL 131 + Y V+++N Q+I + + D ++ + + A+ + L Sbjct: 67 RQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAE------EQGVL 120 Query: 132 TKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARV 191 D++ I LW D +Q R E Q+ D Y + +L+R++ +YIPT++DVL RV Sbjct: 121 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 180 Query: 192 RTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQT 251 +TTG+VE F+ + +++FDVG QR+ER+KWIH FEGVTA+IFC A+S YD Sbjct: 181 KTTGIVETHFTFKDLH------FKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSAYDLV 234 Query: 252 LFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQ 311 L EDE+ NRM + +LFD + F TS +LFLNK D+FE+K+ PL +C Sbjct: 235 LAEDEEMNRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTIC------F 288 Query: 312 PVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDET 371 P +G + + A +++ KFE+L N D + + T + D K V+ F V + Sbjct: 289 PEYTGANKYDEAASYIQSKFEDL---NKRKDT--KEIYTHFTCSTDTKNVQFVFDAVTDV 343 Query: 372 LRRRNLLEAGLL 383 + + NL + GL Sbjct: 344 IIKNNLKDCGLF 355 >2ODE-A nrPDB Length = 350 Score = 493 bits (1270), Expect = e-140, Method: Composition-based stats. Identities = 136/368 (36%), Positives = 206/368 (55%), Gaps = 24/368 (6%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + KLLLLGAGESGKSTI KQ+K++ + G+ E E Sbjct: 6 AEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDEC 65 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRL 131 K Y V+++N Q+I + + ++A+ +L + G + + Sbjct: 66 KQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA-------DDARQLFVLAGSAEEGVM 118 Query: 132 TKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARV 191 T ++A I+ LW+D +Q +R E Q+ D Y + +L R+S NYIPT++DVL RV Sbjct: 119 TPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRV 178 Query: 192 RTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQT 251 +TTG+VE F+ +++FDVGGQR+ER+KWIH FEGVTA+IFC A+S+YD Sbjct: 179 KTTGIVETHFTFKDL------YFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLV 232 Query: 252 LFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQ 311 L EDE+ NRM E+ +LFD + F +TS +LFLNK D+FE+K+ PL +C Sbjct: 233 LAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTIC------Y 286 Query: 312 PVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDET 371 P +G E A +++ +FE+L N D + + T A D K V+ F V + Sbjct: 287 PEYTGSNTYEEAAAYIQCQFEDL---NRRKDT--KEIYTHFTCATDTKNVQFVFDAVTDV 341 Query: 372 LRRRNLLE 379 + + NL E Sbjct: 342 IIKNNLKE 349 >3V00-C nrPDB Length = 356 Score = 489 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 138/369 (37%), Positives = 208/369 (56%), Gaps = 24/369 (6%) Query: 15 TDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSY 74 + E + E+E++++++A+ + KLLLLGAGESGKSTI KQ+K++ Q + E + Sbjct: 12 SAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDPYSLEECLEF 71 Query: 75 VPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKD 134 + +I+ N Q+I + DSA+ KL + ++ + K+ Sbjct: 72 IAIIYGNTLQSILAIVRAMTTLNIQYGDSARQ-------DDARKLMHMADTIEEGTMPKE 124 Query: 135 IAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTT 194 +++ I+ LWKD IQ R +E Q+ D Y + +L+RL Y+PT++DVL +RV+TT Sbjct: 125 MSDIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTT 184 Query: 195 GVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFE 254 G++E QFS N +R+FDVGGQR+ER+KWIH FEGVTA+IFC A+S+YD L E Sbjct: 185 GIIETQFSFKDLN------FRMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAE 238 Query: 255 DEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVS 314 DE+ NRM E+ LF+ + F TS +LFLNK D+FE+K+ PL +C P Sbjct: 239 DEEMNRMHESMHLFNSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTIC------YPEY 292 Query: 315 SGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRR 374 +G E A ++K +F EL N D + + T A D + VK F V + + + Sbjct: 293 AGSNTYEEAGNYIKVQFLEL---NMRRDV--KEIYSHMTCATDTQNVKFVFDAVTDIIIK 347 Query: 375 RNLLEAGLL 383 NL + GL Sbjct: 348 ENLKDCGLF 356 >6OIK-A nrPDB Length = 354 Score = 486 bits (1250), Expect = e-138, Method: Composition-based stats. Identities = 132/373 (35%), Positives = 200/373 (53%), Gaps = 26/373 (6%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ IE+ ++++ + KLLLLGAGESGKSTI KQ+K++ + GF ++ Sbjct: 7 AEDKAAVERSKMIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDV 66 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRL-DYPR 130 K Y PV+++N Q++ + D E A + + ++ R+ D Sbjct: 67 KQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDK-------ERKADAKMVCDVVSRMEDTEP 119 Query: 131 LTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYAR 190 + ++ + LW D IQE R E Q+ D KY +++L R+ +Y PT++D+L R Sbjct: 120 FSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTR 179 Query: 191 VRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQ 250 V+TTG+VE F+ + +RLFDVGGQR+ER+KWIH FE VTA+IFC A+S YDQ Sbjct: 180 VKTTGIVETHFTFKNLH------FRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQ 233 Query: 251 TLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDY 310 L EDE NRM E+ LFD + F TS +LFLNK D+F +K+ PL +C Sbjct: 234 VLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTIC------ 287 Query: 311 QPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDE 370 P +G E A +++ +FE +N +P+ + + T A D ++ F V + Sbjct: 288 FPEYTGPNTYEDAAAYIQAQFES---KNRSPN---KEIYCHMTCATDTNNIQVVFDAVTD 341 Query: 371 TLRRRNLLEAGLL 383 + NL GL Sbjct: 342 IIIANNLRGCGLY 354 >2GTP-A nrPDB Length = 323 Score = 481 bits (1237), Expect = e-136, Method: Composition-based stats. Identities = 135/347 (38%), Positives = 196/347 (56%), Gaps = 24/347 (6%) Query: 37 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF 96 KLLLLGAGESGKSTI KQ+K++ + G+ E E K Y V+++N Q+I + Sbjct: 1 REVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRL 60 Query: 97 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN 156 + DSA+ +L + G + +T ++A I+ LWKD +Q R Sbjct: 61 KIDFGDSARA-------DDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSR 113 Query: 157 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL 216 E Q+ D Y + +L R++ NYIPT++DVL RV+TTG+VE F+ + +++ Sbjct: 114 EYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLH------FKM 167 Query: 217 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC 276 FDVGGQR+ER+KWIH FEGVTA+IFC A+S+YD L EDE+ NRM E+ +LFD + Sbjct: 168 FDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKW 227 Query: 277 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY 336 F TS +LFLNK D+FE+K+ PL +C P +G E A +++ +FE+L Sbjct: 228 FTDTSIILFLNKKDLFEEKIKKSPLTIC------YPEYAGSNTYEEAAAYIQCQFEDL-- 279 Query: 337 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 N D + + T A D K V+ F V + + + NL + GL Sbjct: 280 -NKRKDT--KEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 323 >1TAG-A nrPDB Length = 324 Score = 463 bits (1190), Expect = e-131, Method: Composition-based stats. Identities = 131/348 (37%), Positives = 191/348 (54%), Gaps = 24/348 (6%) Query: 36 KHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKE 95 KLLLLGAGESGKSTI KQ+K++ Q G+ E ++ +I+ N Q+I + Sbjct: 1 ARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTT 60 Query: 96 FAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARG 155 DSA+ KL + ++ + K++++ I+ LWKD IQ R Sbjct: 61 LNIQYGDSARQ-------DDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFDRA 113 Query: 156 NELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYR 215 +E Q+ D Y + +L+RL Y+PT++DVL +RV+TTG++E QFS N +R Sbjct: 114 SEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLN------FR 167 Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQP 275 +FDVGGQR+ER+KWIH FEGVT +IF AA+S YD L ED++ NRM E+ LF+ + Sbjct: 168 MFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHR 227 Query: 276 CFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELY 335 F TS +LFLNK D+F +K+ L++C P +G E A ++K +F EL Sbjct: 228 YFATTSIVLFLNKKDVFSEKIKKAHLSIC------FPDYNGPNTYEDAGNYIKVQFLEL- 280 Query: 336 YQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 N D + + T A D + VK F V + + + NL + GL Sbjct: 281 --NMRRDV--KEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 324 >1ZCB-A nrPDB Length = 362 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 106/371 (28%), Positives = 195/371 (52%), Gaps = 16/371 (4%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + K+LLLGAGESGKST KQ++++ FD+ Sbjct: 7 AEDKAAVERSKMIDRNLREDGERSARLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 66 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRL 131 + + P I++NV + +++L D ++ D+ + + +A + + R+ Sbjct: 67 EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRV 126 Query: 132 TKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARV 191 I LW+D IQ R E Q+ + KY ++NL +L +YIP+++D+L AR Sbjct: 127 FLQYLPAIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARR 186 Query: 192 RTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQT 251 T G+ E F + +++ DVGGQR+ER++W F+ VT+++F + SE+DQ Sbjct: 187 PTKGIHEYDF------EIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQV 240 Query: 252 LFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQ 311 L ED Q NR+ E+ +F+ ++ F S +LFLNK D+ E+KV V ++ ++F +++ Sbjct: 241 LMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQVV--SIKDYFLEFE 298 Query: 312 PVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDET 371 ++++ KF ++ D+ R + TTA++ + ++ F+ V +T Sbjct: 299 GDPHCLRDVQ--------KFLVECFRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDT 350 Query: 372 LRRRNLLEAGL 382 + NL + L Sbjct: 351 ILHDNLKQLML 361 >2BCJ-Q nrPDB Length = 353 Score = 448 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 126/376 (33%), Positives = 200/376 (53%), Gaps = 33/376 (8%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + KLLLLG GESGKST KQ++++ +G+ + + Sbjct: 7 AEDKAAVERSKMIDRNLREDGERSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDK 66 Query: 72 KSYVPVIHANVYQTIKLLHDGTKEFAQN---ETDSAKYMLSSESIAIGEKLSEIGGRLDY 128 + + +++ N++ ++ + E + A L E Sbjct: 67 RGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK-----------V 115 Query: 129 PRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLY 188 + I++LW DP IQE R E Q+ D TKY + +L R++D +Y+PT++DVL Sbjct: 116 SAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLR 175 Query: 189 ARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEY 248 RV TTG++E F ++R+ DVGGQR+ERRKWIH FE VT+++F A+SEY Sbjct: 176 VRVPTTGIIEYPFDL------QSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEY 229 Query: 249 DQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFR 308 DQ L E + +NRM E+K LF ++ P F+ +S +LFLNK D+ E+K++ L Sbjct: 230 DQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL------V 283 Query: 309 DYQPVSSGKQE-IEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKL 367 DY P G Q + A EF+ K F +L PD D++ + T A D + ++ F Sbjct: 284 DYFPEYDGPQRDAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFVFAA 337 Query: 368 VDETLRRRNLLEAGLL 383 V +T+ + NL E L+ Sbjct: 338 VKDTILQLNLKEYNLV 353 >2XTZ-A nrPDB Length = 354 Score = 446 bits (1147), Expect = e-126, Method: Composition-based stats. Identities = 347/347 (100%), Positives = 347/347 (100%) Query: 37 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF 96 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF Sbjct: 8 HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEF 67 Query: 97 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN 156 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN Sbjct: 68 AQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGN 127 Query: 157 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL 216 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL Sbjct: 128 ELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRL 187 Query: 217 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC 276 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC Sbjct: 188 FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPC 247 Query: 277 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY 336 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY Sbjct: 248 FEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKFEELYY 307 Query: 337 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 383 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL Sbjct: 308 QNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGLL 354 >6OIJ-A nrPDB Length = 353 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 127/376 (33%), Positives = 199/376 (52%), Gaps = 33/376 (8%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGEL 71 ED ++ I+R + ++ + + KLLLLG GESGKST KQ++++ G+ E + Sbjct: 7 AEDKAAVERSKMIDRNLREDGEKARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDK 66 Query: 72 KSYVPVIHANVYQTIKLLHDGT---KEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDY 128 + + +++ N++ ++ + K + E + A +L E Sbjct: 67 RGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK-----------V 115 Query: 129 PRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLY 188 I+TLW+DP IQE R E Q+ D KY + ++ R++ + Y+PT++DVL Sbjct: 116 TTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLR 175 Query: 189 ARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEY 248 RV TTG++E F ++R+ DVGGQR+ERRKWIH FE VT+++F A+SEY Sbjct: 176 VRVPTTGIIEYPFDLEN------IIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEY 229 Query: 249 DQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFR 308 DQ L E + +NRM E+K LF ++ P F+ +S +LFLNK D+ E K+L L Sbjct: 230 DQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHL------V 283 Query: 309 DYQPVSSGKQE-IEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKL 367 DY P G Q + A EF+ K F +L PD D++ + T A D + ++ F Sbjct: 284 DYFPEFDGPQRDAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFVFAA 337 Query: 368 VDETLRRRNLLEAGLL 383 V +T+ + NL E L+ Sbjct: 338 VKDTILQLNLKEYNLV 353 >4QJ3-A nrPDB Length = 379 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 127/375 (33%), Positives = 200/375 (53%), Gaps = 33/375 (8%) Query: 13 EDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELK 72 E + EIER++ ++ + + KLLLLG GESGKST KQ++++ +G+ + + + Sbjct: 34 EAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKR 93 Query: 73 SYVPVIHANVYQTIKLLHDGTKEFAQN---ETDSAKYMLSSESIAIGEKLSEIGGRLDYP 129 + +++ N++ ++ + E + A L E Sbjct: 94 GFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK-----------VS 142 Query: 130 RLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYA 189 + I++LW DP IQE R E Q+ D TKY + +L R++D +Y+PT++DVL Sbjct: 143 AFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRV 202 Query: 190 RVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYD 249 RV TTG++E F ++R+ DVGGQR+ERRKWIH FE VT+++F A+SEYD Sbjct: 203 RVPTTGIIEYPFDL------QSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYD 256 Query: 250 QTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRD 309 Q L E + +NRM E+K LF ++ P F+ +S +LFLNK D+ E+K++ L D Sbjct: 257 QVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL------VD 310 Query: 310 YQPVSSGKQE-IEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLV 368 Y P G Q + A EF+ K F +L PD D++ + T A D + ++ F V Sbjct: 311 YFPEYDGPQRDAQAAREFILKMFVDL-----NPDS-DKIIYSHFTCATDTENIRFVFAAV 364 Query: 369 DETLRRRNLLEAGLL 383 +T+ + NL E L+ Sbjct: 365 KDTILQLNLKEYNLV 379 >1ZCA-A nrPDB Length = 359 Score = 417 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 109/373 (29%), Positives = 190/373 (50%), Gaps = 23/373 (6%) Query: 12 TEDTDENTQAAEIERRIEQEA--KAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEG 69 ED ++ I+R + ++ +A + + K+LLLGAGESGKST KQ++++ FD+ Sbjct: 7 AEDKAAVERSKMIDRNLREDGERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQK 66 Query: 70 ELKSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYP 129 L + I N+ + ++L D + S +A K G P Sbjct: 67 ALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENK----AGLPVEP 122 Query: 130 RLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYA 189 + + LW+D I+E +R +E Q+ + KY ++NL R+ +NY P+K+D+L A Sbjct: 123 ATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLA 182 Query: 190 RVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYD 249 R T G+VE F +++ DVGGQR++R+KW F+G+T+++F + SEYD Sbjct: 183 RKATKGIVEHDFVIKK------IPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYD 236 Query: 250 QTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRD 309 Q L ED + NR++E+ +F+ ++ F S +LFLNK D+ +KV V ++ + F D Sbjct: 237 QVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSV--SIKKHFPD 294 Query: 310 YQPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVD 369 ++ +E ++ + F+ + P + TTA+D + ++ F V Sbjct: 295 FK---GDPHRLEDVQRYLVQCFDRKRRNRSKP------LFHHFTTAIDTENIRFVFHAVK 345 Query: 370 ETLRRRNLLEAGL 382 +T+ + NL + L Sbjct: 346 DTILQENLKDIML 358 >5VAI-A nrPDB Length = 380 Score = 416 bits (1070), Expect = e-117, Method: Composition-based stats. Identities = 110/388 (28%), Positives = 188/388 (48%), Gaps = 39/388 (10%) Query: 13 EDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFD-EGEL 71 E+ + +IE++++++ + + +LLLLGAGESGKSTI KQ+++L GF+ + E Sbjct: 15 EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEK 74 Query: 72 KSYVPVIHANVYQTIKLLHDGTK------EFAQNETD-SAKYMLSSESIAIGEKLSEIGG 124 + V I N+ + I+ + E A E Y+LS ++ + Sbjct: 75 ATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFD------- 127 Query: 125 RLDYPRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKE 184 + E + LW+D ++ R NE Q+ DC +Y ++ + + +Y+P+ + Sbjct: 128 ------FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQ 181 Query: 185 DVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAA 244 D+L RV T+G+ E +F N + +FDVGGQR+ERRKWI F VTA+IF A Sbjct: 182 DLLRCRVLTSGIFETKFQVDKVN------FHMFDVGGQRDERRKWIQCFNDVTAIIFVVA 235 Query: 245 ISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVC 304 S Y+ + ED Q NR+ E LF + S +LFLNK D+ +KVL + Sbjct: 236 SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIE 295 Query: 305 EWFRDY---------QPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTA 355 ++F ++ P + A F++ +F + +TA + T A Sbjct: 296 DYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRI---STASGDGRHYCYPHFTCA 352 Query: 356 LDQKLVKKTFKLVDETLRRRNLLEAGLL 383 +D + +++ F + ++R +L + LL Sbjct: 353 VDTENIRRVFNDCRDIIQRMHLRQYELL 380 >4FID-A nrPDB Length = 340 Score = 339 bits (870), Expect = 1e-93, Method: Composition-based stats. Identities = 104/351 (29%), Positives = 170/351 (48%), Gaps = 35/351 (9%) Query: 36 KHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKE 95 ++LLG+GESGKSTI KQ+K+LF GF E E ++ I +NV ++ L + + Sbjct: 3 AKPITVMLLGSGESGKSTIAKQLKILFGGGFPEQERATHKSSICSNVVTCMRTLIEQSAI 62 Query: 96 FAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARG 155 KY S+ + ++ + ++ +E LW D IQ T Sbjct: 63 LNHP----MKYQPKSKEFTTEDPVTL--------PFSPELVGDVEALWADEGIQATYEES 110 Query: 156 NELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYR 215 + Q+PDC KYL EN+KR++ +Y+PT+ED+++ R +TTG+ E F + Sbjct: 111 AKFQLPDCAKYLFENVKRIAMEDYVPTEEDLIHNRTKTTGIHEYDFVVKD------IPFH 164 Query: 216 LFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQP 275 L DVGGQR+ER+KW+ F V IF +++EYD L+ED +R+ E+ +F ++ Sbjct: 165 LIDVGGQRSERKKWVSFFSDVDCAIFVTSLAEYDMKLYEDGNTSRLTESIAVFKDIMTNE 224 Query: 276 CFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKKKF---- 331 + ++FLNK D+FE+K+ VPLN P +G +++++ F Sbjct: 225 FLKGAVKLIFLNKMDLFEEKLTKVPLNT------IFPEYTGGDNAVMGAQYIQQLFTGKL 278 Query: 332 --EELYYQNTA-----PDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRR 375 EE+ V+ T A D +K+ F L + + + Sbjct: 279 QTEEMNISGADGTANIEGAVNEKVYTNPTNATDGSNIKRVFMLAVDVIMKN 329 >6G79-A nrPDB Length = 225 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 66/188 (35%), Positives = 95/188 (50%), Gaps = 28/188 (14%) Query: 196 VVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFED 255 +VE F+ + +RLFDVGGQR+ER+KWIH FE VTA+IFC +S+Y Sbjct: 66 IVETHFTFKNLH------FRLFDVGGQRSERKKWIHCFEDVTAIIFCVDLSDY------- 112 Query: 256 EQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSS 315 NRM E+ LFD + F TS +LFLNK D+F +K+ PL +C P + Sbjct: 113 ---NRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTIC------FPEYT 163 Query: 316 GKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFKLVDETLRRR 375 G E A +++ +FE +N +P+ + + T A D + F V + + Sbjct: 164 GPNTYEDAAAYIQAQFES---KNRSPN---KEIYCHMTCATDTNNAQVIFDAVTDIIIAN 217 Query: 376 NLLEAGLL 383 NL GL Sbjct: 218 NLRGCGLY 225 Score = 75.2 bits (183), Expect = 4e-14, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 31/51 (60%) Query: 12 TEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLF 62 E+ ++ IE+ ++++ + KLLLLGA SGKSTI KQ+K++ Sbjct: 4 AEERAALERSKAIEKNLKEDGISAAKDVKLLLLGADNSGKSTIVKQMKIIH 54 >6GDG-D nrPDB Length = 248 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 54/197 (27%), Positives = 87/197 (44%), Gaps = 28/197 (14%) Query: 196 VVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFED 255 + E +F N + +FDVGGQR+ERRKWI F VTA+IF S+Y Sbjct: 71 IFETKFQVDKVN------FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDY------- 117 Query: 256 EQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDY----- 310 NR+ E LF + S +LFLNK D+ +KVL + ++F ++ Sbjct: 118 ---NRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT 174 Query: 311 ----QPVSSGKQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTALDQKLVKKTFK 366 P + A F++ +F + +TA + T A+D + ++ F Sbjct: 175 PEDATPEPGEDPRVTRAKYFIRDEFLRI---STASGDGRHYCYPHFTCAVDTENARRIFN 231 Query: 367 LVDETLRRRNLLEAGLL 383 + ++R +L + LL Sbjct: 232 DCRDIIQRMHLRQYELL 248 Score = 68.2 bits (165), Expect = 6e-12, Method: Composition-based stats. Identities = 18/50 (36%), Positives = 33/50 (66%) Query: 13 EDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLF 62 E+ + +IE++++++ + + +LLLLGA SGKSTI KQ+++L Sbjct: 10 EEKAQREANKKIEKQLQKDKQVYRATHRLLLLGADNSGKSTIVKQMRILH 59 >3LVQ-E nrPDB Length = 497 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 44/120 (36%), Gaps = 18/120 (15%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 + ++DVGGQ R W H + G +IF ++ D R+ E ++ Sbjct: 364 KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQELH 413 Query: 270 WVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQEIE 321 ++ ++F NK D+ ++K+ + W+ +SG E Sbjct: 414 RIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYE 473 >2A5F-A nrPDB Length = 175 Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 44/120 (36%), Gaps = 18/120 (15%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 + ++DVGGQ R W H + G +IF ++ D R+ E ++ Sbjct: 55 KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQELH 104 Query: 270 WVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQEIE 321 ++ ++F NK D+ ++K+ + W+ +SG E Sbjct: 105 RIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYE 164 >3AQ4-A nrPDB Length = 184 Score = 54.4 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 10/84 (11%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H F+ +IF ++ D+ + ++ +RM Sbjct: 60 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRM------ 113 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI 291 L + ++F NK D+ Sbjct: 114 ----LNEDELRDAVLLVFANKQDL 133 >5NZV-F nrPDB Length = 181 Score = 52.0 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 49/120 (40%), Gaps = 18/120 (15%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 + ++DVGGQ R W H + VIF ++ ++R+ E +E+ Sbjct: 59 KNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSND----------RSRIGEAREVMQ 108 Query: 270 WVLKQPCFEKTSFMLFLNKFDIFE--------KKVLDVPLNVCEWFRDYQPVSSGKQEIE 321 +L + ++++F NK D+ E +K+ + WF +SG+ E Sbjct: 109 RMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYE 168 >5UF8-A nrPDB Length = 181 Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 45/122 (36%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W + F+ +IF ++ D R+ E +E Sbjct: 57 EYKNISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRD----------RIAEAREE 106 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 +L + ++F NK D+ +K+ + W+ ++G Sbjct: 107 LQQMLNEDELRDALLLVFANKQDLPNAMNAAEITEKLGLHSIRQRPWYIQATCATTGDGL 166 Query: 320 IE 321 E Sbjct: 167 YE 168 >6BBQ-A nrPDB Length = 520 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 43/120 (35%), Gaps = 18/120 (15%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 + ++DVGG R W H + G +IF ++ D R+ E ++ Sbjct: 401 KNVKFNVWDVGGLDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQELH 450 Query: 270 WVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQEIE 321 ++ ++F NK D+ ++K+ + W+ +SG E Sbjct: 451 RIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYE 510 >3LRP-A nrPDB Length = 181 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 44/122 (36%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H + +IF ++ ++ E+ +RM Sbjct: 57 EFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRM------ 110 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 + + + ++F NK D+ +K+ + WF + G Sbjct: 111 ----INEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGL 166 Query: 320 IE 321 E Sbjct: 167 YE 168 >2B6H-A nrPDB Length = 192 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 44/122 (36%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H F+ +IF ++ + R+ E+ + Sbjct: 69 EYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND----------RERVQESADE 118 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 +L++ ++F NK D+ K+ L W+ + G Sbjct: 119 LQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGL 178 Query: 320 IE 321 + Sbjct: 179 YD 180 >6FAE-B nrPDB Length = 213 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 44/122 (36%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H F+ +IF ++ ++ E+ RM+ EL Sbjct: 89 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 148 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 ++F NK D+ K+ L W+ +SG Sbjct: 149 ----------RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGL 198 Query: 320 IE 321 E Sbjct: 199 YE 200 >3O47-A nrPDB Length = 329 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 44/122 (36%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H F+ +IF ++ ++ E+ RM+ EL Sbjct: 205 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 264 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 ++F NK D+ K+ L W+ +SG Sbjct: 265 ----------RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGL 314 Query: 320 IE 321 E Sbjct: 315 YE 316 >4YLG-A nrPDB Length = 173 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 10/84 (11%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H ++ A+IF ++ D R+ E +E Sbjct: 53 EYKNISFTVWDVGGQDKIRPLWRHYYQNTQAIIFVVDSNDRD----------RIGEAREE 102 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI 291 +L + ++F NK D+ Sbjct: 103 LMKMLNEDEMRNAILLVFANKHDL 126 >4M9Q-A nrPDB Length = 227 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 60/167 (35%), Gaps = 23/167 (13%) Query: 168 MENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERR 227 ++N + + +N I + D T G F+ N+ ++ +FD+GG +N R Sbjct: 12 LDNAGKTTLLNSIQGEVD--RDTTPTFG-----FNSTTLNEGKYKI-EVFDLGGGKNIRG 63 Query: 228 KWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLN 287 W V A+++ ++ R E+K VL+ +F N Sbjct: 64 VWKKYLAEVHAIVYVVDAAD----------PGRFEESKMTMAEVLENQFMRDKPICIFAN 113 Query: 288 KFDI-----FEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKK 329 K D+ + V + L C + P ++ + ++ Sbjct: 114 KQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRD 160 >5DI3-B nrPDB Length = 263 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 60/167 (35%), Gaps = 23/167 (13%) Query: 168 MENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERR 227 ++N + + +N I + D T G F+ N+ ++ +FD+GG +N R Sbjct: 12 LDNAGKTTLLNSIQGEVD--RDTTPTFG-----FNSTTLNEGKYKI-EVFDLGGGKNIRG 63 Query: 228 KWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLN 287 W V A+++ ++ R E+K VL+ +F N Sbjct: 64 VWKKYLAEVHAIVYVVDAAD----------PGRFEESKMTMAEVLENQFMRDKPICIFAN 113 Query: 288 KFDI-----FEKKVLDVPLNVCEWFRDYQPVSSGKQEIEHAYEFVKK 329 K D+ + V + L C + P ++ + ++ Sbjct: 114 KQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRD 160 >5DE3-A nrPDB Length = 169 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 49/112 (43%), Gaps = 17/112 (15%) Query: 182 TKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIF 241 ++ED+ T G F+ ++ G +++D+GGQ++ R W + F+ A+I+ Sbjct: 21 SEEDIT-TITPTQG-----FNIKSLSR-DGFNLKIWDIGGQKSIRPYWRNYFDQTDALIY 73 Query: 242 CAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFE 293 ++ R+ E++ +L++ ++F NK D+ Sbjct: 74 VIDSAD----------SKRLSESEFELTELLQEEKMTGVPLLVFANKQDLVG 115 >1KSG-A nrPDB Length = 186 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 11/91 (12%) Query: 201 FSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNR 260 F+ + G ++DVGGQ++ R W + FE +I+ ++ + R Sbjct: 52 FNIKTL-EHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSAD----------RQR 100 Query: 261 MMETKELFDWVLKQPCFEKTSFMLFLNKFDI 291 M + + +L + + ++F NK D+ Sbjct: 101 MQDCQRELQSLLVEERLAGATLLIFANKQDL 131 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 30/57 (52%), Gaps = 9/57 (15%) Query: 28 IEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQ 84 +++ + E+ + +LL+LG +GK+TI K+ F+ ++ + P + N+ Sbjct: 9 LKKMKQKEREL-RLLMLGLDNAGKTTILKK--------FNGEDVDTISPTLGFNIKT 56 >2X77-A nrPDB Length = 189 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 10/82 (12%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 + ++D+GGQ R W F AVI+ ++ D RM K Sbjct: 64 KNISFEVWDLGGQTGVRPYWRCYFSDTDAVIYVVDSTDRD----------RMGVAKHELY 113 Query: 270 WVLKQPCFEKTSFMLFLNKFDI 291 +L + K+ ++F NK D+ Sbjct: 114 ALLDEDELRKSLLLIFANKQDL 135 >1Z6X-A nrPDB Length = 180 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 10/84 (11%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGGQ R W H F+ +IF ++ + R+ E + Sbjct: 57 EYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSND----------RERIQEVADE 106 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI 291 +L +LF NK D+ Sbjct: 107 LQKMLLVDELRDAVLLLFANKQDL 130 >6DFF-C nrPDB Length = 193 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGG R W H F+ +IF ++ ++ E+ RM+ EL Sbjct: 69 EYKNISFTVWDVGGLDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 128 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 ++F NK D+ K+ L W+ +SG Sbjct: 129 ----------RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGL 178 Query: 320 IE 321 E Sbjct: 179 YE 180 >1J2J-A nrPDB Length = 166 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 18/122 (14%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 + + ++DVGG R W H F+ +IF ++ ++ E+ RM+ EL Sbjct: 42 EYKNISFTVWDVGGLDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 101 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDI--------FEKKVLDVPLNVCEWFRDYQPVSSGKQE 319 ++F NK D+ K+ L W+ +SG Sbjct: 102 ----------RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGL 151 Query: 320 IE 321 E Sbjct: 152 YE 153 >1YZG-A nrPDB Length = 179 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 31/83 (37%), Gaps = 10/83 (12%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 + ++D+GGQ + R W + +I + ++ E+ RM Sbjct: 57 VKNTHFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRM------- 109 Query: 269 DWVLKQPCFEKTSFMLFLNKFDI 291 L K + ++F NK D+ Sbjct: 110 ---LAHEDLRKAAVLIFANKQDM 129 >1F6B-A nrPDB Length = 198 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 35/82 (42%), Gaps = 10/82 (12%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 +G + FD+GG RR W + + ++F ++++ R++E+KE Sbjct: 66 IAGMTFTTFDLGGHIQARRVWKNYLPAINGIVFLVDCADHE----------RLLESKEEL 115 Query: 269 DWVLKQPCFEKTSFMLFLNKFD 290 D ++ ++ NK D Sbjct: 116 DSLMTDETIANVPILILGNKID 137 >2GAO-A nrPDB Length = 208 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 41/95 (43%), Gaps = 14/95 (14%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 +G + FD+GG RR W + + ++F +++ +R++E+K Sbjct: 76 IAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADH----------SRLVESKVEL 125 Query: 269 DWVLKQPCFEKTSFMLFLNKFD----IFEKKVLDV 299 + ++ ++ NK D I E+K+ ++ Sbjct: 126 NALMTDETISNVPILILGNKIDRTDAISEEKLREI 160 >2H57-A nrPDB Length = 190 Score = 44.7 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 25/112 (22%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 K S + +FD+ GQ R W H ++ A+IF S+ + RM+ KE Sbjct: 63 KSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSD----------RLRMVVAKEE 112 Query: 268 FDWVLKQPCF--EKTSFMLFLNKFDIFE-------------KKVLDVPLNVC 304 D +L P + + F NK D+ + + + D P ++C Sbjct: 113 LDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLENIKDKPWHIC 164 >1MOZ-A nrPDB Length = 183 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 10/81 (12%) Query: 210 SGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFD 269 ++D+GGQ + R W + AVIF ++ D RM + Sbjct: 60 KNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKD----------RMSTASKELH 109 Query: 270 WVLKQPCFEKTSFMLFLNKFD 290 +L++ + + ++F NK D Sbjct: 110 LMLQEEELQDAALLVFANKQD 130 >4BAS-A nrPDB Length = 199 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Query: 208 KKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKEL 267 +K + +FD+GG + R W ++ + AVIF S++ + + M++ +++ Sbjct: 59 EKGRVAFTVFDMGGAKKFRGLWETYYDNIDAVIFVVDSSDHLRLCVVKSEIQAMLKHEDI 118 Query: 268 FDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCE 305 + P + F+ F NK D K + + + Sbjct: 119 RREL---PGGGRVPFLFFANKMDAAGAKTAAELVEILD 153 >4ZI3-A nrPDB Length = 190 Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 36/98 (36%), Gaps = 12/98 (12%) Query: 197 VEIQFSPVGENKKSGEVYRL--FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFE 254 + ++L +D+GGQR R W FE +I+ ++ Sbjct: 44 HITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSAD------- 96 Query: 255 DEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIF 292 + R ET + +L++ ++F NK D+ Sbjct: 97 ---RKRFEETGQELTELLEEEKLSCVPVLIFANKQDLL 131 Score = 32.0 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 18/31 (58%) Query: 28 IEQEAKAEKHIRKLLLLGAGESGKSTIFKQI 58 + + A ++LLLG +GK+T+ KQ+ Sbjct: 7 LRKLKSAPDQEVRILLLGLDNAGKTTLLKQL 37 >2H16-A nrPDB Length = 183 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 33/85 (38%), Gaps = 10/85 (11%) Query: 209 KSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELF 268 + + ++D+GGQ + R W + VI ++ ++ E+ +M Sbjct: 63 INNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKM------- 115 Query: 269 DWVLKQPCFEKTSFMLFLNKFDIFE 293 L K ++F NK D+ E Sbjct: 116 ---LAHEDLRKAGLLIFANKQDVKE 137 Score = 28.2 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 22/50 (44%), Gaps = 8/50 (16%) Query: 33 KAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANV 82 + K++++G +GK+TI Q F E+ P I +NV Sbjct: 17 RGSHQEHKVIIVGLDNAGKTTILYQ--------FSMNEVVHTSPTIGSNV 58 >4V0N-A nrPDB Length = 169 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 34/88 (38%), Gaps = 10/88 (11%) Query: 204 VGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMME 263 V E +K + +FD+ G R W + AV+F ++ + + ++ M++ Sbjct: 44 VDEVEKGPLTFTVFDMSGAGRYRTLWEQYYREADAVVFVVDSADKLRMVVARDEMEHMLK 103 Query: 264 TKELFDWVLKQPCFEKTSFMLFLNKFDI 291 + K + F NK D+ Sbjct: 104 HSNM----------RKVPILYFANKKDL 121 >6GNI-B nrPDB Length = 167 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 10/80 (12%) Query: 211 GEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDW 270 + FD+GG RR W F V ++F ++ R E + D Sbjct: 44 NIKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAAD----------PERFDEARVELDA 93 Query: 271 VLKQPCFEKTSFMLFLNKFD 290 + + F++ NK D Sbjct: 94 LFNIAELKDVPFVILGNKID 113 >1M2O-B nrPDB Length = 190 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 10/80 (12%) Query: 211 GEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDW 270 + FD+GG RR W F V ++F ++ R E + D Sbjct: 66 NIKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAAD----------PERFDEARVELDA 115 Query: 271 VLKQPCFEKTSFMLFLNKFD 290 + + F++ NK D Sbjct: 116 LFNIAELKDVPFVILGNKID 135 >3BH6-A nrPDB Length = 164 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 35/98 (35%), Gaps = 12/98 (12%) Query: 197 VEIQFSPVGENKKSGEVYRL--FDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFE 254 + ++L +D+GG R R W FE +I+ ++ Sbjct: 31 HITPTQGFNIKSVQSQGFKLNVWDIGGLRKIRPYWRSYFENTDILIYVIDSAD------- 83 Query: 255 DEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIF 292 + R ET + +L++ ++F NK D+ Sbjct: 84 ---RKRFEETGQELTELLEEEKLSCVPVLIFANKQDLL 118 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 9/21 (42%), Positives = 15/21 (71%) Query: 38 IRKLLLLGAGESGKSTIFKQI 58 ++LLLG +GK+T+ KQ+ Sbjct: 4 EVRILLLGLDNAGKTTLLKQL 24 >4WNR-A nrPDB Length = 349 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%) Query: 30 QEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKS 73 + K + K+LL+G GE+GK+++ K+ L GFD E ++ Sbjct: 33 EGEKKPLNEVKVLLVGDGEAGKTSLLKR---LLGEGFDGNEHQT 73 >4M8N-E nrPDB Length = 199 Score = 31.2 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 37 HIRKLLLLGAGESGKSTIFKQ-IKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKE 95 KL++LG+G GKS + Q ++ +F +D SY + + Q + + D Sbjct: 5 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGT 64 >2QGA-B nrPDB Length = 465 Score = 31.2 bits (69), Expect = 0.81, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 36/105 (34%), Gaps = 15/105 (14%) Query: 270 WVLKQPCFEKTSFMLFLNKFDIFEKKVLD----------VPLNVCEWFRDYQPVSSGKQE 319 ++K + ++LFLN+ ++F +KV D + + R + Sbjct: 30 ALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEEETNHD 89 Query: 320 IEHAYEFVKKKFEELYYQNTAPDRVDRVFKIYRTTAL-DQKLVKK 363 ++ FVK+K + D + ++ D V Sbjct: 90 VKAVEYFVKEKL----KNSKREDLLKIKEYVHYLCTSEDINNVAY 130 >2GWD-A nrPDB Length = 449 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 176 DINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEG 235 ++ P + ++L +V TG+ + F + +V +L G +R ++ + Sbjct: 356 TADWTPAEREMLRNKVPVTGL-KTPFRDGLLKHVAEDVLKLAKDGLERRGYKE-VGFLNA 413 Query: 236 VTAVI 240 VT V+ Sbjct: 414 VTEVV 418 >6FKM-A nrPDB Length = 715 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 14/37 (37%) Query: 247 EYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFM 283 Y++ L D +R++ LF + S + Sbjct: 111 NYNKVLLIDRATSRLIACGSLFQGTCTVRNLQNVSII 147 >6I3U-A nrPDB Length = 615 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 27/206 (13%), Positives = 69/206 (33%), Gaps = 27/206 (13%) Query: 130 RLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYA 189 + ++ + ++ ++ + + D K + +++ + L Sbjct: 282 TFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLP---------LEP 332 Query: 190 RVRTTGVV-EIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEY 248 +V+ G++ E N + ++ D G K+ LF+ + + Sbjct: 333 QVKIRGIIPETATLAKSANMPAQLFFKTEDGG-------KYPVLFKHGD------DLRQD 379 Query: 249 DQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLN--KFDIFEKKVLDVPLNVCEW 306 L ++++ + L + ++ FL + + +VLD ++ + Sbjct: 380 QLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFLQWIQGSVPVAEVLDTEGSIQNF 439 Query: 307 FRDYQPVSSGKQ--EIEHAYEFVKKK 330 FR Y P +G E +VK Sbjct: 440 FRKYAPSENGPNGISAEVMDTYVKSC 465 >6HLU-A nrPDB Length = 974 Score = 28.2 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 12/66 (18%) Query: 18 NTQAAEIERRIEQEAKAEK---------HIRKLLLLGAGESGKSTIFKQIKLLFQTGFDE 68 Q E R+ Q + + K+ L+G G +GK+++ KQ L FD Sbjct: 451 VKQGKEAVRQYFQSIEEARSKGEALVHLQEIKVHLIGDGMAGKTSLLKQ---LIGETFDP 507 Query: 69 GELKSY 74 E +++ Sbjct: 508 KESQTH 513 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.129 0.341 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,183,209 Number of Sequences: 36641 Number of extensions: 569509 Number of successful extensions: 2155 Number of sequences better than 10.0: 57 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1887 Number of HSP's gapped (non-prelim): 171 length of query: 383 length of database: 10,336,785 effective HSP length: 99 effective length of query: 284 effective length of database: 6,709,326 effective search space: 1905448584 effective search space used: 1905448584 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.8 bits)