BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P17655 (700 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1KFU-L nrPDB 1439 0.0 3DF0-A nrPDB 1321 0.0 1QXP-A nrPDB 1030 0.0 1MDW-A nrPDB 654 0.0 2NQA-A nrPDB 523 e-148 2NQG-A nrPDB 506 e-143 1ZCM-A nrPDB 502 e-142 2P0R-A nrPDB 400 e-111 6BDT-A nrPDB 354 6e-98 1KFX-S nrPDB 179 3e-45 4OKH-A nrPDB 179 3e-45 3BOW-B nrPDB 175 6e-44 1NP8-A nrPDB 162 3e-40 1JUO-A nrPDB 97 3e-20 5MRA-A nrPDB 96 5e-20 1F4Q-A nrPDB 96 6e-20 1GJY-A nrPDB 94 2e-19 3AAJ-A nrPDB 63 4e-10 2I7A-A nrPDB 61 2e-09 1Y1X-A nrPDB 49 9e-06 3QRX-A nrPDB 42 6e-04 1S6I-A nrPDB 42 8e-04 3PM8-A nrPDB 39 0.008 4MVF-A nrPDB 39 0.011 1CLM-A nrPDB 36 0.055 2QFE-A nrPDB 35 0.14 5UKG-A nrPDB 34 0.18 3U0K-A nrPDB 34 0.18 4JWQ-A nrPDB 34 0.25 2AAO-A nrPDB 34 0.25 5A2H-A nrPDB 34 0.27 5NIL-D nrPDB 33 0.32 3EK4-A nrPDB 33 0.39 3KF9-A nrPDB 33 0.48 3K21-A nrPDB 33 0.51 3SIA-A nrPDB 33 0.60 2N6A-A nrPDB 32 0.64 4IL1-A nrPDB 32 0.77 6O20-F nrPDB 32 0.80 3WFN-B nrPDB 32 0.84 4I2Y-A nrPDB 32 0.85 3O4Y-A nrPDB 32 0.92 1IJ5-A nrPDB 32 1.00 4ORC-B nrPDB 32 1.0 1FJ2-A nrPDB 32 1.1 5I0I-E nrPDB 32 1.1 1DTL-A nrPDB 32 1.1 2L1W-A nrPDB 32 1.1 2N7L-C nrPDB 32 1.1 6HCS-A nrPDB 32 1.1 2TN4-A nrPDB 31 1.6 5VLN-A nrPDB 31 1.8 4E53-A nrPDB 31 1.8 2F2P-A nrPDB 30 2.8 6MI5-X nrPDB 30 3.2 1ZFS-A nrPDB 30 3.3 1ZMZ-A nrPDB 30 3.7 4GJF-A nrPDB 30 4.4 3NCG-A nrPDB 30 4.8 2GGM-A nrPDB 30 4.8 2K2A-A nrPDB 29 5.5 2PMY-A nrPDB 29 5.7 2JNF-A nrPDB 29 5.7 2OBH-A nrPDB 29 5.9 2HF5-A nrPDB 29 6.0 1TOP-A nrPDB 29 6.2 6NUD-J nrPDB 29 7.9 1TNP-A nrPDB 29 8.4 >1KFU-L nrPDB Length = 699 Score = 1439 bits (3724), Expect = 0.0, Method: Compositional matrix adjust. Identities = 695/699 (99%), Positives = 697/699 (99%) Query: 2 AGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 61 AGIAAKLAKDREAAEGLGSH+RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK Sbjct: 1 AGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 60 Query: 62 ELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 121 ELGPYSSKTRG+ WKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL Sbjct: 61 ELGPYSSKTRGMRWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 120 Query: 122 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 181 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL Sbjct: 121 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 180 Query: 182 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 241 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS Sbjct: 181 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 240 Query: 242 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 301 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC Sbjct: 241 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 300 Query: 302 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 361 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM Sbjct: 301 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 360 Query: 362 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 421 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK Sbjct: 361 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 420 Query: 422 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 481 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE Sbjct: 421 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 480 Query: 482 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQL 541 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDG RRLFAQL Sbjct: 481 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL 540 Query: 542 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 601 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW Sbjct: 541 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 600 Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 661 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN Sbjct: 601 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 660 Query: 662 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL Sbjct: 661 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 699 >3DF0-A nrPDB Length = 714 Score = 1321 bits (3418), Expect = 0.0, Method: Compositional matrix adjust. Identities = 655/700 (93%), Positives = 681/700 (97%) Query: 1 MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF 60 MAGIA KLAKDREAAEGLGSH+RAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEI Sbjct: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEI 120 Query: 121 LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 LARVVPL+QSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL Sbjct: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC 240 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGC Sbjct: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 Query: 241 SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN 300 SIDITSAADSEA+T+QKLVKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDN Sbjct: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 Query: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK 360 CPSWNT+DPE R LT R EDGEFWMSFSDFLRHYSRLEICNLTPDTLT D+YKKWKLTK Sbjct: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR 420 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDED+EDGE GCTFLVGLIQKHRRRQR Sbjct: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 Query: 421 KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG 480 KMGEDMHTIGFGIYEVPEEL+GQTNIHLSKNFFLT RARERSDTFINLREVLNRFKLPPG Sbjct: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 Query: 481 EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ 540 EY+LVPSTFEP+K+GDFCIRVFSEKKADYQ VDDEIEAN+EE + +E+DI DGFRRLFAQ Sbjct: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 LAGEDAEISAFELQTILRRVLAKR+DIKSDGFSIETCKIMVDMLD DGSGKLGLKEFYIL Sbjct: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD 660 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK+PCQLHQVIVARFADD+LIIDFD Sbjct: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 Query: 661 NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 NFVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 >1QXP-A nrPDB Length = 900 Score = 1030 bits (2662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 488/703 (69%), Positives = 592/703 (84%), Gaps = 4/703 (0%) Query: 1 MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF 60 MAGIA KLAKDREAAEGLGSH+RAIKYLNQDYE LRNECLEAG LFQDP+FP + +LGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPAFPPVSHSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGP SSKT GI+WKRPTE+ ++PQFI+ GATRTDICQGALGD WLLAAIASLTLNE I Sbjct: 61 KELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETI 120 Query: 121 LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 L RVVP QSFQE YAGIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSAL Sbjct: 121 LHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC 240 LEKAYAK+NG YEALSGG T+E FEDFTGG+ EWY+L+K P +L++II KAL++GSLLGC Sbjct: 181 LEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGC 240 Query: 241 SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN 300 SI+I+ D EAITF+ LV+GHAYSVT A++V G LIR+RNPWGEVEW G W+DN Sbjct: 241 SINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDN 300 Query: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK 360 WN +DP ERE+L + EDGEFWMSF DF+R +++LEICNLTPD L S T + W T Sbjct: 301 SYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLRNWNTTF 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED--EDEEDGESGCTFLVGLIQKHRRR 418 +G WRRGSTAGGCRNYP TFW+NPQ+ I+LEE D +D + ESGC+FL+ L+QKHRRR Sbjct: 361 YEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDSRESGCSFLLALMQKHRRR 420 Query: 419 QRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLP 478 +R+ G DM TIGF +Y+VP EL+GQ +HL ++FFL N +R +S+ FINLREV NR +LP Sbjct: 421 ERRFGRDMETIGFAVYQVPRELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLP 479 Query: 479 PGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANL-EEFDISEDDIDDGFRRL 537 PGEYI+VPSTFEPNK+GDF +R FSEKKA Q +DD+I+ANL +E +SE++IDD F+ L Sbjct: 480 PGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTL 539 Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 F++LAG+D EIS ELQTIL R+++K +D++++GFS+E+C+ MV+++D DG+GKLGL EF Sbjct: 540 FSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 ILW +I+ Y I+R+ D+D+SG+M++YEMR A+E AGFK+PCQLHQVIVARFADD+LII Sbjct: 600 NILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELII 659 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 DFDNFVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 660 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 702 Score = 172 bits (437), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 77/166 (46%), Positives = 117/166 (70%) Query: 534 FRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV ++DSD +GKLG Sbjct: 733 FRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 792 Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADD 653 +EF LW I+K+Q IY+ + DRSGT+ S E+ A E AGF + ++ +I+ R++D+ Sbjct: 793 FEEFKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDE 852 Query: 654 QLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 +DFDNF+ CLVRL+ +F+ F+ LD TG I++++ WL ++ Sbjct: 853 TGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 898 >1MDW-A nrPDB Length = 328 Score = 654 bits (1687), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/328 (93%), Positives = 320/328 (97%) Query: 19 GSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRP 78 GSH+RAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGFKELGPYSSKTRGIEWKRP Sbjct: 1 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 60 Query: 79 TEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGI 138 TEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEILARVVPL+QSFQENYAGI Sbjct: 61 TEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 120 Query: 139 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 198 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG Sbjct: 121 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 180 Query: 199 ATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKL 258 ATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGCSIDITSAADSEA+T+QKL Sbjct: 181 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 240 Query: 259 VKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRR 318 VKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDNCPSWNT+DPE R LT R Sbjct: 241 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 300 Query: 319 HEDGEFWMSFSDFLRHYSRLEICNLTPD 346 EDGEFWMSFSDFLRHYSRLEICNLTPD Sbjct: 301 QEDGEFWMSFSDFLRHYSRLEICNLTPD 328 >2NQA-A nrPDB Length = 326 Score = 523 bits (1347), Expect = e-148, Method: Compositional matrix adjust. Identities = 239/323 (73%), Positives = 283/323 (87%) Query: 24 AIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICA 83 A+KYL QD++ LR +CL++G LF+DP FPA PSALG+K+LGP S +T+GI WKRPTE+C Sbjct: 4 ALKYLGQDFKTLRQQCLDSGVLFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELCP 63 Query: 84 DPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQF 143 PQFI+GGATRTDICQG LGDCWLLAAIASLTLNEE+L RVVP +Q FQENYAGIFHFQF Sbjct: 64 SPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFHFQF 123 Query: 144 WQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEG 203 WQYGEWVEVV+DDRLPTK+G+LLF+HS +G+EFWSALLEKAYAK+NGCYEAL+GG+T EG Sbjct: 124 WQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVEG 183 Query: 204 FEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHA 263 FEDFTGGI+E+Y+LKKPP NL++II+KAL GSLLGCSID+ SAA++EAIT QKLVK HA Sbjct: 184 FEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCSIDVYSAAEAEAITSQKLVKSHA 243 Query: 264 YSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGE 323 YSVTG EEV G +KLIR+RNPWGEVEW+G W+D+ P WN IDP +E L ++ EDGE Sbjct: 244 YSVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSDDAPEWNHIDPRRKEELDKKVEDGE 303 Query: 324 FWMSFSDFLRHYSRLEICNLTPD 346 FWMS SDF+R +SRLEICNL+PD Sbjct: 304 FWMSLSDFVRQFSRLEICNLSPD 326 >2NQG-A nrPDB Length = 339 Score = 506 bits (1302), Expect = e-143, Method: Compositional matrix adjust. Identities = 234/330 (70%), Positives = 275/330 (83%) Query: 17 GLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWK 76 GLG H+ AIKYL QDYE LR CL+ G LFQD +FP + +LGFKELGP SSKT GI+WK Sbjct: 2 GLGRHENAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWK 61 Query: 77 RPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYA 136 RPTE+ ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLNE IL RVVP QSFQE YA Sbjct: 62 RPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYA 121 Query: 137 GIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALS 196 GIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSALLEKAYAK+NG YEALS Sbjct: 122 GIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALS 181 Query: 197 GGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQ 256 GG T+E FEDFTGG+ EWY+L+K P +L++II KAL++GSLLGCSI+I+ D EAITF+ Sbjct: 182 GGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFK 241 Query: 257 KLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLT 316 LV+GHAYSVT A++V G LIR+RNPWGEVEW G W+DN WN +DP ERE+L Sbjct: 242 NLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLR 301 Query: 317 RRHEDGEFWMSFSDFLRHYSRLEICNLTPD 346 + EDGEFWMSF DF+R +++LEICNLTPD Sbjct: 302 VKMEDGEFWMSFRDFIREFTKLEICNLTPD 331 >1ZCM-A nrPDB Length = 321 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 229/320 (71%), Positives = 274/320 (85%) Query: 24 AIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICA 83 AIKYL QDYE LR CL++GTLF+D +FP +P +LG+K+LGP SSKT GI+WKRPTE+ + Sbjct: 2 AIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLS 61 Query: 84 DPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQF 143 +PQFI+ GATRTDICQGALGDCWLLAAIASLTLN+ +L RVVP QSFQ YAGIFHFQ Sbjct: 62 NPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQL 121 Query: 144 WQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEG 203 WQ+GEWV+VVVDD LP KDG+L+FVHSAEG+EFWSALLEKAYAK+NG YEALSGG+T+E Sbjct: 122 WQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEA 181 Query: 204 FEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHA 263 FEDFTGG+ EWYEL+K P +L++II KAL++GSLLGCSIDI+S D EAITF+KLVKGHA Sbjct: 182 FEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHA 241 Query: 264 YSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGE 323 YSVTGA++V G + LIR+RNPWGEVEWTG W+D+ WN +DP ER++L + EDGE Sbjct: 242 YSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGE 301 Query: 324 FWMSFSDFLRHYSRLEICNL 343 FWMSF DF+R ++RLEICNL Sbjct: 302 FWMSFRDFMREFTRLEICNL 321 >2P0R-A nrPDB Length = 333 Score = 400 bits (1027), Expect = e-111, Method: Compositional matrix adjust. Identities = 191/326 (58%), Positives = 241/326 (73%), Gaps = 6/326 (1%) Query: 23 RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEIC 82 R Q +E +R ECL+ GTLF+D FPA S+L + E WKRP EI Sbjct: 13 RITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSE-----RPQIPFVWKRPGEIV 67 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQ 142 +P+FI+GGATRTDICQG LGDCWLLAAIASLTLN++ LARV+P +QSF YAGIFHFQ Sbjct: 68 KNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQ 127 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQ+ EW++VV+DDRLPT L+F+HSA+ +EFWSALLEKAYAK+NG YEAL GG+ E Sbjct: 128 FWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIE 187 Query: 203 GFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGH 262 EDFTGG+AE ++ K+ P N ++I++KAL++GSLLGC ID SAA+SEA T L+KGH Sbjct: 188 AMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGH 247 Query: 263 AYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRH-ED 321 AYSVTG ++V G +LIRIRNPWG+VEW G W+D+ P W ++ P E++RL +D Sbjct: 248 AYSVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDD 307 Query: 322 GEFWMSFSDFLRHYSRLEICNLTPDT 347 GEFWM+F DF H+ ++EICNLTPD Sbjct: 308 GEFWMAFKDFKAHFDKVEICNLTPDA 333 >6BDT-A nrPDB Length = 382 Score = 354 bits (909), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 176/364 (48%), Positives = 231/364 (63%), Gaps = 54/364 (14%) Query: 32 YEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGG 91 +E L +CLE L+ DP FP ++L + + P WKRP EIC +P+FII G Sbjct: 16 FEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQ-----FVWKRPPEICENPRFIIDG 70 Query: 92 ATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVE 151 A RTDICQG LGD W LAAIA LTLN+ +L RV+P +QSF ENYAGIFHFQFW+YGEWV+ Sbjct: 71 ANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVD 130 Query: 152 VVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGI 211 VV+DD LPT + +L+F S +EFWSALLEKAYAK++G YEAL GG TTE EDFTGG+ Sbjct: 131 VVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGV 190 Query: 212 AEWYELKKPPPNLFKIIQKALQKGSLLGCSID----ITSAADSEAITFQK---------- 257 AE++E++ P +++KI++KA+++GSL+GCSID +T + + Sbjct: 191 AEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMD 250 Query: 258 ----------------------------------LVKGHAYSVTGAEEVESNGSLQKLIR 283 LV+GHAYSVTG +EV G KL+R Sbjct: 251 NSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVR 310 Query: 284 IRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRR-HEDGEFWMSFSDFLRHYSRLEICN 342 +RNPWG+VEW G W+D W+ +D +E+ RL + EDGEFWMS+ DF+ H+++LEICN Sbjct: 311 LRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICN 370 Query: 343 LTPD 346 LT D Sbjct: 371 LTAD 374 >1KFX-S nrPDB Length = 184 Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 81/166 (48%), Positives = 120/166 (72%) Query: 534 FRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 FRRLFAQLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV ++DSD +GKLG Sbjct: 17 FRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 76 Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADD 653 +EF LW I+++Q IY++ D DRSGT+ S E+ A E AGF + L+ +I+ R++D+ Sbjct: 77 FEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDE 136 Query: 654 QLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 +DFDNF+ CLVRL+ +F+ FK LD + TG I++++ WL ++ Sbjct: 137 SGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 182 >4OKH-A nrPDB Length = 189 Score = 179 bits (455), Expect = 3e-45, Method: Composition-based stats. Identities = 79/169 (46%), Positives = 121/169 (71%) Query: 527 EDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 E + FR +F Q+AG+D EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D+ Sbjct: 7 ESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 66 Query: 587 DGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVI 646 DGSGKL L+EF+ LW KI+ +QKI++ D D+SGT+NSYEMR A+ +AGF + QL+ +I Sbjct: 67 DGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII 126 Query: 647 VARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWL 695 R+AD + IDFD+F+ C VRLE +F+ F D + G I+L+++ WL Sbjct: 127 TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWL 175 >3BOW-B nrPDB Length = 184 Score = 175 bits (444), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 78/166 (46%), Positives = 117/166 (70%) Query: 534 FRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV ++DSD +GKLG Sbjct: 17 FRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 76 Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADD 653 +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF + ++ +I+ R++D+ Sbjct: 77 FEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDE 136 Query: 654 QLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 +DFDNF+ CLVRL+ +F+ F+ LD TG I++++ WL ++ Sbjct: 137 TGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 182 >1NP8-A nrPDB Length = 159 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 73/147 (49%), Positives = 106/147 (72%) Query: 534 FRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV ++DSD +GKLG Sbjct: 13 FRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 72 Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADD 653 +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF + ++ +I+ R++D+ Sbjct: 73 FEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDE 132 Query: 654 QLIIDFDNFVRCLVRLETLFKIFKQLD 680 +DFDNF+ CLVRL+ +F+ F+ LD Sbjct: 133 TGNMDFDNFISCLVRLDAMFRAFRSLD 159 >1JUO-A nrPDB Length = 198 Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 55/155 (35%), Positives = 85/155 (54%), Gaps = 10/155 (6%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG---FSIETCKIMVDMLDSDGSGKLGL 594 FA +AG+D +I A ELQ L Q + G F++ETC++MV MLD D SG +G Sbjct: 39 FAAVAGQDGQIDADELQRCLT------QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 92 Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQ 654 EF LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ + Sbjct: 93 NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 152 Query: 655 LIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 689 I FD+++ C V+L L F++ D G + Sbjct: 153 KIT-FDDYIACCVKLRALTDSFRRRDTAQQGVVNF 186 >5MRA-A nrPDB Length = 167 Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 55/155 (35%), Positives = 85/155 (54%), Gaps = 10/155 (6%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG---FSIETCKIMVDMLDSDGSGKLGL 594 FA +AG+D +I A ELQ L Q + G F++ETC++MV MLD D SG +G Sbjct: 8 FAAVAGQDGQIDADELQRCLT------QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 61 Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQ 654 EF LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ + Sbjct: 62 NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 121 Query: 655 LIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 689 I FD+++ C V+L L F++ D G + Sbjct: 122 KIT-FDDYIACCVKLRALTDSFRRRDTAQQGVVNF 155 >1F4Q-A nrPDB Length = 165 Score = 95.5 bits (236), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 52/152 (34%), Positives = 86/152 (56%), Gaps = 4/152 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 F+ +AG+D E+ A ELQ L + + FS+ETC+IM+ MLD D +GK+G F Sbjct: 6 FSAVAGQDGEVDAEELQRCLTQ---SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAF 62 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 LW + +++ + +D D SGT+ +E+R+A+ G+++ Q IV R++ + I Sbjct: 63 KELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIF 122 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 689 FD++V C V+L L FK+ D G+ + Sbjct: 123 -FDDYVACCVKLRALTDFFKKRDHLQQGSADF 153 >1GJY-A nrPDB Length = 167 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 55/155 (35%), Positives = 84/155 (54%), Gaps = 10/155 (6%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG---FSIETCKIMVDMLDSDGSGKLGL 594 FA +AG+D +I A ELQ L Q + G F++ETC++MV MLD D SG +G Sbjct: 8 FASVAGQDGQIDADELQRCLT------QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 61 Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQ 654 EF LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ Sbjct: 62 NEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTSG 121 Query: 655 LIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 689 I FD+++ C V+L L F++ D G + Sbjct: 122 KIT-FDDYIACCVKLRALTDSFRRRDSAQQGMVNF 155 >3AAJ-A nrPDB Length = 167 Score = 63.2 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 33/125 (26%), Positives = 68/125 (54%), Gaps = 3/125 (2%) Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 F+ T + ++ M D + + EF +W I +Q ++R D D SG ++ E+++AL Sbjct: 38 FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 97 Query: 632 EEAGFKMPCQLHQVIVARF-ADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 690 +G+++ Q H +++ +F + I FD+F++ + L+ L IF++ D + G I++ Sbjct: 98 --SGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 155 Query: 691 LISWL 695 +L Sbjct: 156 YEQYL 160 >2I7A-A nrPDB Length = 174 Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 41/159 (25%), Positives = 82/159 (51%), Gaps = 8/159 (5%) Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 L ++I A +LQ +L + L D FS++ C+ +V +++ +G+L +EF L Sbjct: 14 LVPRGSDIDATQLQGLLNQELLTGP--PGDMFSLDECRSLVALMELKVNGRLDQEEFARL 71 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA----GFKMPCQLHQVIVARFADDQLI 656 W ++ YQ +++++ G + S ++ KA+E G + +L ++ R++D Sbjct: 72 WKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGR 130 Query: 657 IDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWL 695 + F + V L+RLE + K F+ L + G + L + W+ Sbjct: 131 VSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEMEWM 168 >1Y1X-A nrPDB Length = 191 Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 1/129 (0%) Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 FS+ T + ++ M D + SG++ EF L I ++ +R+ D G ++S E+R AL Sbjct: 60 FSLATTEKLLHMYDKNHSGEITFDEFKDLHHFILSMREGFRKRDSSGDGRLDSNEVRAAL 119 Query: 632 EEAGFKMPCQLHQVIVARFADDQL-IIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 690 +G+++ Q Q ++ +F + + FD++V + + + +F D E TG + Sbjct: 120 LSSGYQVSEQTFQALMRKFDRQRRGSLGFDDYVELSIFVCRVRNVFAFYDRERTGQVTFT 179 Query: 691 LISWLCFSV 699 +++ SV Sbjct: 180 FDTFIGGSV 188 >3QRX-A nrPDB Length = 169 Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEM 627 E K M+ +D DGSG + +EF + T ++ K +R D D SGT+ ++ Sbjct: 64 EEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDL 123 Query: 628 RKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 R+ +E G + +L ++I +D ID D F+R + Sbjct: 124 RRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 Score = 36.2 bits (82), Expect = 0.053, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 13/119 (10%) Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 K +V G++GL E + Q+ ++ + D D SGT+++ E++ A+ GF Sbjct: 5 AKTVVSARRDQKKGRVGLTE-----EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGF 59 Query: 637 K-MPCQLHQVIVARFADDQLIIDFDNFVRCLV-------RLETLFKIFKQLDPENTGTI 687 + ++ ++I D IDF+ F+ + E + K F+ D +N+GTI Sbjct: 60 EPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTI 118 >1S6I-A nrPDB Length = 188 Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 7/101 (6%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDN 661 +I +++++ ID D SGT+ E++ L+ G + M ++ ++ A D ID+ Sbjct: 8 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGE 67 Query: 662 FVRCLVRL------ETLFKIFKQLDPENTGTIELDLISWLC 696 F+ V L E L F D + +G I LD I C Sbjct: 68 FIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQAC 108 >3PM8-A nrPDB Length = 197 Score = 38.9 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPCQLHQVIVARFADDQLIIDFDN 661 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + + Sbjct: 55 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 114 Query: 662 FVRCLVRLETLFKI------FKQLDPENTGTIELD 690 F+ + +T K FK D + G I ++ Sbjct: 115 FLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVE 149 >4MVF-A nrPDB Length = 506 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 7/96 (7%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPCQLHQVIVARFADDQLIIDFD 660 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + Sbjct: 357 VEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYT 416 Query: 661 NFVRCLVRLETLFKI------FKQLDPENTGTIELD 690 +F+ + +T K FK D + G I ++ Sbjct: 417 DFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVE 452 >1CLM-A nrPDB Length = 148 Score = 36.2 bits (82), Expect = 0.055, Method: Compositional matrix adjust. Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 17/143 (11%) Query: 534 FRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592 F+ FA + D I+ EL T++R + + + + M++ +D+DG+G + Sbjct: 12 FKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTI 63 Query: 593 GLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQ 644 EF L + K Q + ++ D D +G +++ E+R + G K+ ++ + Sbjct: 64 DFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDE 123 Query: 645 VIVARFADDQLIIDFDNFVRCLV 667 +I D I+++ FVR +V Sbjct: 124 MIREADIDGDGHINYEEFVRMMV 146 >2QFE-A nrPDB Length = 148 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 31/138 (22%) Query: 360 KMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQ 419 +++G W G +AGGC N+ T NP Y +E+ LI+ RQ Sbjct: 26 RINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTGPL-------------LIELRGPRQ 71 Query: 420 RKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPP 479 +++GF + V G H FL + + F L E+ N +P Sbjct: 72 -------YSVGFEVVTV--STLGDPGPH----GFLRKSSGDYRCGFCYL-ELEN---IPS 114 Query: 480 GEYILVPSTFEPNKDGDF 497 G + ++PSTF P ++G F Sbjct: 115 GIFNIIPSTFLPKQEGPF 132 >5UKG-A nrPDB Length = 419 Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust. Identities = 26/131 (19%), Positives = 59/131 (45%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG G EF + + Sbjct: 295 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTFDFPEFLTMMARK 346 Query: 605 QKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 Y ++ +R D D +G + + E+R + + G K+ ++ ++I D Sbjct: 347 MSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQ 406 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 407 VNYEEFVQMMT 417 >3U0K-A nrPDB Length = 442 Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG G + EF I+ + Sbjct: 318 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTIDFPEFLIMMARK 369 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 370 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 429 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 430 VNYEEFVQMMT 440 >4JWQ-A nrPDB Length = 199 Score = 33.9 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 +Q+ + ++ +D D G + +++K LE +G K+P ++ +D ID+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTI 687 + + L K F+ D +N G I Sbjct: 117 AAALDRKHLSKKLIYCAFRVFDVDNDGEI 145 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 579 IMVDMLDSDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKAL 631 +++D +DSDGSG++ EF + K +R DVD G + + E+ L Sbjct: 97 VLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHIL 154 >2AAO-A nrPDB Length = 166 Score = 33.9 bits (76), Expect = 0.25, Method: Compositional matrix adjust. Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDN 661 +I ++++ ID D+SG + E++ L+ G + ++ ++ A D+ ID+ Sbjct: 25 EIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKE 84 Query: 662 FVRCLVRL------ETLFKIFKQLDPENTGTIELDLISWLC 696 F+ + L + LF F D + +G I D + C Sbjct: 85 FIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQAC 125 >5A2H-A nrPDB Length = 149 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 22/96 (22%), Positives = 50/96 (52%), Gaps = 8/96 (8%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D+DG+G + EF L + K ++ +R D D++G +++ E+R + Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT 111 Query: 633 EAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLV 667 G K+ ++ ++I D I+++ FV+ ++ Sbjct: 112 NLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMM 147 >5NIL-D nrPDB Length = 371 Score = 33.5 bits (75), Expect = 0.32, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Query: 492 NKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAF 551 +D D + K+A +D +I+ N D ++ ++D + R+ A +AGE +I+ Sbjct: 143 QQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLD--YTRIVAPMAGEVTQITTL 200 Query: 552 ELQTIL 557 + QT++ Sbjct: 201 QGQTVI 206 >3EK4-A nrPDB Length = 451 Score = 33.1 bits (74), Expect = 0.39, Method: Compositional matrix adjust. Identities = 26/131 (19%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 327 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 378 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 379 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 438 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 439 VNYEEFVQMMT 449 Score = 29.3 bits (64), Expect = 5.8, Method: Compositional matrix adjust. Identities = 63/278 (22%), Positives = 109/278 (39%), Gaps = 49/278 (17%) Query: 423 GEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTF--INLREVLNRFKLPPG 480 GE++ T G+ + EL G N H F + E T+ + L+ + KLP Sbjct: 162 GEELFT---GVVPILVELDGDVNGHK----FSVSGEGEGDATYGKLTLKFICTTGKLPVP 214 Query: 481 EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDI---DDGFRRL 537 LV + + ++ FS + D+ D ++ + E I E I DDG + Sbjct: 215 WPTLVTTL-------TYGVQCFS-RYPDHMKQHDFFKSAMPEGYIQERTIFFKDDGNYKT 266 Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 A++ FE T++ R+ K D K DG +I K+ + D Sbjct: 267 RAEVK--------FEGDTLVNRIELKGIDFKEDG-NILGHKLEYNTRDQ----------- 306 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLI 656 + +I ++++ + D D GT+ + E+ + G +L +I AD Sbjct: 307 -LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 365 Query: 657 IDFDNFVRCLVRL-------ETLFKIFKQLDPENTGTI 687 IDF F+ + R E + + F+ D + G I Sbjct: 366 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 403 >3KF9-A nrPDB Length = 149 Score = 33.1 bits (74), Expect = 0.48, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 8/91 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D SGT+++ E++ A+ GF+ ++ ++I D IDF+ F+ Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFL 67 Query: 664 RCLV-------RLETLFKIFKQLDPENTGTI 687 + + E + K F+ D + TG I Sbjct: 68 QMMTAKMGERDSREEIMKAFRLFDDDETGKI 98 Score = 30.4 bits (67), Expect = 3.0, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 7/80 (8%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEM 627 E K M+ +D DGSG + +EF + T ++ K +R D D +G ++ + Sbjct: 44 EEIKKMIADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNL 103 Query: 628 RKALEEAGFKMPCQLHQVIV 647 ++ +E G M + Q ++ Sbjct: 104 KRVAKELGENMTDEELQEMI 123 Score = 29.3 bits (64), Expect = 6.1, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 582 DMLDSDGSGKLGLKEFYILWT------KIQKYQKIYREIDVDRSGTMN 623 D+ D+DGSG + KE + K ++ +K+ +ID D SGT++ Sbjct: 15 DLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTID 62 >3K21-A nrPDB Length = 191 Score = 32.7 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 ++K + + +D D G + +++K LE+ G K+P ++ +D ID+ F+ Sbjct: 51 VEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTI 687 + + L K F+ D +N G I Sbjct: 111 AAALDRKQLSKKLIYCAFRVFDVDNDGEI 139 Score = 32.3 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 6/74 (8%) Query: 564 RQDIKSDGFSIE-TCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVD 617 ++ ++ DG + +++D +DSDGSGK+ EF ++ K +R DVD Sbjct: 75 KKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFIAAALDRKQLSKKLIYCAFRVFDVD 134 Query: 618 RSGTMNSYEMRKAL 631 G + + E+ L Sbjct: 135 NDGEITTAELAHIL 148 >3SIA-A nrPDB Length = 220 Score = 32.7 bits (73), Expect = 0.60, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 34/65 (52%) Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 S +T M+ + D+D +G + EF ++ ++ ++ RSGT+ +E+ AL Sbjct: 84 LSPQTALRMMRIFDTDFNGHISFYEFMAMYKFMELAYNLFVMNARARSGTLEPHEILPAL 143 Query: 632 EEAGF 636 ++ GF Sbjct: 144 QQLGF 148 >2N6A-A nrPDB Length = 173 Score = 32.3 bits (72), Expect = 0.64, Method: Compositional matrix adjust. Identities = 27/135 (20%), Positives = 62/135 (45%), Gaps = 16/135 (11%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 26 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 77 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 78 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 137 Query: 657 IDFDNFVRCLVRLET 671 ++++ FV+ + T Sbjct: 138 VNYEEFVQMMTGAST 152 >4IL1-A nrPDB Length = 823 Score = 32.3 bits (72), Expect = 0.77, Method: Compositional matrix adjust. Identities = 34/182 (18%), Positives = 78/182 (42%), Gaps = 44/182 (24%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 25 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 657 IDFDNFVRCLV----------------------------RLETLFKIFKQLDPENTGTIE 688 ++++ FV+ + ++ L K FK+LD +N+G++ Sbjct: 137 VNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLS 196 Query: 689 LD 690 ++ Sbjct: 197 VE 198 Score = 32.0 bits (71), Expect = 1.0, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 15/90 (16%) Query: 580 MVDMLDSDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 ++D+ D+DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 215 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 274 Query: 633 -EAGFKMP-CQLHQVIVARFADDQLIIDFD 660 G + QL Q++ D+ II+ D Sbjct: 275 MMVGNNLKDTQLQQIV------DKTIINAD 298 >6O20-F nrPDB Length = 169 Score = 32.3 bits (72), Expect = 0.80, Method: Compositional matrix adjust. Identities = 26/131 (19%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 45 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 96 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 97 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 156 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 157 VNYEEFVQMMT 167 >3WFN-B nrPDB Length = 182 Score = 32.0 bits (71), Expect = 0.84, Method: Compositional matrix adjust. Identities = 26/131 (19%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 31 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 82 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 83 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 142 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 143 VNYEEFVQMMT 153 >4I2Y-A nrPDB Length = 421 Score = 32.0 bits (71), Expect = 0.85, Method: Compositional matrix adjust. Identities = 25/131 (19%), Positives = 60/131 (45%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG G EF + + Sbjct: 297 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTFDFPEFLTMMARK 348 Query: 605 -------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 ++ ++ +R D D +G + + E+R + + G K+ ++ ++I D Sbjct: 349 MNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQ 408 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 409 VNYEEFVQMMT 419 >3O4Y-A nrPDB Length = 196 Score = 32.0 bits (71), Expect = 0.92, Method: Compositional matrix adjust. Identities = 22/100 (22%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 +QK + + +D + G + ++RK LE +G +P ++ +D ID+ F+ Sbjct: 54 VQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTIELDLISWLCFS 698 + L K F+ D +N G I ++ + F+ Sbjct: 114 AAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFN 153 Score = 29.3 bits (64), Expect = 6.3, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 579 IMVDMLDSDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKAL 631 +++D +DSDGSG + EF ++ K +R DVD G + + E+ L Sbjct: 94 LLLDQIDSDGSGNIDYTEFLAAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVL 151 >1IJ5-A nrPDB Length = 323 Score = 32.0 bits (71), Expect = 1.00, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 11/122 (9%) Query: 557 LRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDV 616 L++VLAK D +G K + M+++D G++ + + +R+ID Sbjct: 144 LKQVLAKYADTIPEG----PLKKLFVMVENDTKGRMSYITLVAVANDLAALVADFRKIDT 199 Query: 617 DRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID--FDNFVR---CLVRLET 671 + +GT++ E R+ GF Q + R+AD+ D F +V CL+ L Sbjct: 200 NSNGTLSRKEFREHFVRLGFDKKSV--QDALFRYADEDESDDVGFSEYVHLGLCLLVLRI 257 Query: 672 LF 673 L+ Sbjct: 258 LY 259 >4ORC-B nrPDB Length = 170 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 15/90 (16%) Query: 580 MVDMLDSDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 ++D+ D+DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 Query: 633 -EAGFKMP-CQLHQVIVARFADDQLIIDFD 660 G + QL Q++ D+ II+ D Sbjct: 118 MMVGNNLKDTQLQQIV------DKTIINAD 141 >1FJ2-A nrPDB Length = 232 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 2/79 (2%) Query: 85 PQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVV-PLNQSFQENYAGIFHFQF 143 PQ IGGA R GDC L + +L E L +V P N +F+ Y G+ H Sbjct: 155 PQGPIGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPANVTFK-TYEGMMHSSC 213 Query: 144 WQYGEWVEVVVDDRLPTKD 162 Q V+ +D LP D Sbjct: 214 QQEMMDVKQFIDKLLPPID 232 >5I0I-E nrPDB Length = 145 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/144 (20%), Positives = 69/144 (47%), Gaps = 19/144 (13%) Query: 534 FRRLFAQLAGEDAE--ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGK 591 F+ F+ LA +D + I+ EL T++R + + + + M++ +D+DG+G Sbjct: 11 FKEAFS-LADKDGDGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGT 61 Query: 592 LGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLH 643 + EF + + K ++ +R D D +G +++ E+R + G K+ ++ Sbjct: 62 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 121 Query: 644 QVIVARFADDQLIIDFDNFVRCLV 667 ++I D ++++ FV+ + Sbjct: 122 EMIREADIDGDGQVNYEEFVQMMT 145 >1DTL-A nrPDB Length = 161 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 18/105 (17%) Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 L ED IS EL ++R +L + + E + M+D +D DGSG + EF ++ Sbjct: 29 LGAEDGSISTKELGKVMR-MLGQNP-------TPEELQEMIDEVDEDGSGTVDFDEFLVM 80 Query: 601 WTKIQK----------YQKIYREIDVDRSGTMNSYEMRKALEEAG 635 + K ++R D + G ++ E++ L+ G Sbjct: 81 MVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG 125 >2L1W-A nrPDB Length = 149 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/103 (22%), Positives = 52/103 (50%), Gaps = 8/103 (7%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEM 627 E + M+ +D+DG+G + EF L K K ++ ++ D D++G +++ E+ Sbjct: 46 EELQDMISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL 105 Query: 628 RKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLVRL 669 R + G K+ ++ Q+I D ++++ FV+ ++ + Sbjct: 106 RHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 >2N7L-C nrPDB Length = 141 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 9/96 (9%) Query: 511 AVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSD 570 ++DD +A +E+ + + +F L ED IS EL ++R + Sbjct: 15 SMDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVMRML--------GQ 65 Query: 571 GFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK 606 + E + M+D +D DGSG + EF ++ + K Sbjct: 66 NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMK 101 >6HCS-A nrPDB Length = 167 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 22/144 (15%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 25 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 657 IDFDNFVRCLVR------LETLFK 674 ++++ FV+ + LE LF+ Sbjct: 137 VNYEEFVQMMTAKLEGTGLEVLFQ 160 >2TN4-A nrPDB Length = 159 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 21/136 (15%) Query: 574 IETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE- 626 I K DM D+DG G + +KE + + ++ I E+D D SGT++ E Sbjct: 16 IAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEF 75 Query: 627 ----MRKALEEAGFKMPCQLHQV--IVARFADDQLIIDFDNFVRCL------VRLETLFK 674 +R+ E+A K +L ++ I R AD ID + V E + Sbjct: 76 LVMMVRQMKEDAKGKSEEELAELFRIFDRNADG--YIDAEELAEIFRASGEHVTDEEIES 133 Query: 675 IFKQLDPENTGTIELD 690 + K D N G I+ D Sbjct: 134 LMKDGDKNNDGRIDFD 149 >5VLN-A nrPDB Length = 120 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%) Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 L ED IS EL ++R + + E + M+D +D DGSG + EF ++ Sbjct: 29 LGAEDGSISTKELGKVMRML--------GQNPTPEELQEMIDEVDEDGSGTVDFDEFLVM 80 Query: 601 WTKIQK 606 + K Sbjct: 81 MVRSMK 86 >4E53-A nrPDB Length = 185 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/130 (20%), Positives = 61/130 (46%), Gaps = 16/130 (12%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D+DG+G + EF + + Sbjct: 32 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 83 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLI 656 K ++ +R D D +G +++ E+R + G K+ ++ ++I D Sbjct: 84 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 143 Query: 657 IDFDNFVRCL 666 ++++ FV+ + Sbjct: 144 VNYEEFVQMM 153 >2F2P-A nrPDB Length = 179 Score = 30.4 bits (67), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/96 (20%), Positives = 48/96 (50%), Gaps = 8/96 (8%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D+DG+G + EF + + K ++ +R D D +G +++ E+R + Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 633 EAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLV 667 G K+ ++ ++I D ++++ FV+ + Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147 >6MI5-X nrPDB Length = 117 Score = 30.0 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 22/113 (19%) Query: 576 TCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 T K+ + D D G + LKE + + ++D D+ GT+++ E++ + EA Sbjct: 4 TTKVDIAAFDPDKDGTIDLKE------ALAAGSAAFDKLDPDKDGTLDAKELKGRVSEAD 57 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIE 688 K +L D D + L + FK +P+N GTI+ Sbjct: 58 LK----------------KLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTID 94 >1ZFS-A nrPDB Length = 93 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 3/58 (5%) Query: 543 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 G+ ++S EL+ +L+ L+ D++ D +++ KIM + LD +G G++ +EF +L Sbjct: 23 GDKYKLSKKELKDLLQTELSSFLDVQKDADAVD--KIMKE-LDENGDGEVDFQEFVVL 77 >1ZMZ-A nrPDB Length = 98 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 582 DMLDSDGSGKLGLKEFYILW------TKIQKYQKIYREIDVDRSGTMN 623 D+ D+DG+G + +KE + K ++ +K+ EID + +G MN Sbjct: 38 DLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 85 >4GJF-A nrPDB Length = 89 Score = 29.6 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 9/95 (9%) Query: 512 VDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 +DD +A +E+ + + +F Q A ED IS EL ++R + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVQGA-EDGCISTKELGKVMRML--------GQN 51 Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK 606 + E + M+D +D DGSG + EF ++ + K Sbjct: 52 PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMK 86 >3NCG-A nrPDB Length = 486 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 32/56 (57%), Gaps = 6/56 (10%) Query: 583 MLDSDGSGKLGLKEFYILWT------KIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 M D DGSGK+ KE + L++ ++++ + I ++D ++ G ++ E + L+ Sbjct: 425 MFDKDGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 >2GGM-A nrPDB Length = 172 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 582 DMLDSDGSGKLGLKEFYILWT------KIQKYQKIYREIDVDRSGTMN 623 D+ D+DG+G + +KE + K ++ +K+ EID + +G MN Sbjct: 38 DLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 85 >2K2A-A nrPDB Length = 70 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 556 ILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 ++R +LA+ + S E M+D +D+DGSG + +EF + T Sbjct: 24 VMREILAELDET----LSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 66 >2PMY-A nrPDB Length = 91 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 565 QDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ----KYQKIYREIDVDRSG 620 Q DG + + + D++ SG+L +EF L T+++ + +++ +D DR G Sbjct: 17 QGADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG 76 Query: 621 TMNSYEMRKAL 631 + E + Sbjct: 77 AITFQEFARGF 87 >2JNF-A nrPDB Length = 158 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 4/58 (6%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 D E + + ++R +LA+ + S E M+D +D+DGSG + +EF + T Sbjct: 101 DKEGNGYISTDVMREILAELDET----LSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >2OBH-A nrPDB Length = 143 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 582 DMLDSDGSGKLGLKEFYILWT------KIQKYQKIYREIDVDRSGTMN 623 D+ D+DG+G + +KE + K ++ +K+ EID + +G MN Sbjct: 13 DLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 60 >2HF5-A nrPDB Length = 68 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 15/63 (23%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D+DG+G + EF + + K ++ +R D D +G +++ E+R + Sbjct: 6 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 65 Query: 633 EAG 635 G Sbjct: 66 NLG 68 >1TOP-A nrPDB Length = 162 Score = 29.3 bits (64), Expect = 6.2, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 21/132 (15%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE----- 626 K DM D+DG G + KE + + ++ I E+D D SGT++ E Sbjct: 23 KAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM 82 Query: 627 MRKALEEAGFKMPCQLHQV--IVARFADDQLIIDFDNFVRCL------VRLETLFKIFKQ 678 +R+ E+A K +L I + AD ID + L V E + + K Sbjct: 83 VRQMKEDAKGKSEEELANCFRIFDKNADG--FIDIEELGEILRATGEHVTEEDIEDLMKD 140 Query: 679 LDPENTGTIELD 690 D N G I+ D Sbjct: 141 SDKNNDGRIDFD 152 >6NUD-J nrPDB Length = 758 Score = 28.9 bits (63), Expect = 7.9, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 463 DTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSE-KKADYQAVDDEIEANLE 521 DT+ N ++ N F + P+ +F + K DY A+ I+ L Sbjct: 102 DTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELA 161 Query: 522 EFDISEDDID 531 EF+ ++ ID Sbjct: 162 EFEFNQAQID 171 >1TNP-A nrPDB Length = 90 Score = 28.9 bits (63), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 574 IETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMN 623 I K DM D+DG G + KE + + ++ I E+D D SGT++ Sbjct: 19 IAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTID 74 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1KFU-L nrPDB 1317 0.0 3DF0-A nrPDB 1261 0.0 1QXP-A nrPDB 1219 0.0 1MDW-A nrPDB 649 0.0 2NQG-A nrPDB 634 0.0 1ZCM-A nrPDB 613 e-176 2NQA-A nrPDB 609 e-174 2P0R-A nrPDB 552 e-157 6BDT-A nrPDB 521 e-148 1KFX-S nrPDB 270 1e-72 3BOW-B nrPDB 269 2e-72 4OKH-A nrPDB 258 5e-69 1NP8-A nrPDB 243 2e-64 1F4Q-A nrPDB 206 2e-53 1JUO-A nrPDB 204 9e-53 5MRA-A nrPDB 203 2e-52 1GJY-A nrPDB 201 1e-51 2I7A-A nrPDB 179 4e-45 3AAJ-A nrPDB 159 5e-39 1Y1X-A nrPDB 153 2e-37 1S6I-A nrPDB 99 5e-21 3QRX-A nrPDB 99 6e-21 Sequences not found previously or not previously below threshold: 4IL1-A nrPDB 82 9e-16 2AAO-A nrPDB 82 1e-15 3KF9-A nrPDB 81 2e-15 3EK4-A nrPDB 81 2e-15 3U0K-A nrPDB 77 2e-14 2GGM-A nrPDB 77 2e-14 1GGZ-A nrPDB 77 4e-14 2L1W-A nrPDB 77 4e-14 4OY4-A nrPDB 76 4e-14 5UKG-A nrPDB 76 6e-14 2OBH-A nrPDB 75 7e-14 1CLM-A nrPDB 75 8e-14 4I2Y-A nrPDB 75 1e-13 2F2P-A nrPDB 75 1e-13 3WFN-B nrPDB 75 1e-13 6O20-F nrPDB 74 2e-13 4E53-A nrPDB 74 3e-13 2N6A-A nrPDB 73 4e-13 1DTL-A nrPDB 73 4e-13 5I0I-E nrPDB 73 4e-13 5D43-A nrPDB 72 6e-13 5A2H-A nrPDB 72 7e-13 6HCS-A nrPDB 72 9e-13 1S6J-A nrPDB 70 3e-12 2TN4-A nrPDB 67 2e-11 1TOP-A nrPDB 67 3e-11 5E37-A nrPDB 65 8e-11 3NCG-A nrPDB 65 1e-10 2LMV-A nrPDB 65 2e-10 4MVF-A nrPDB 64 2e-10 3PM8-A nrPDB 64 2e-10 1OQP-A nrPDB 63 3e-10 2LHI-A nrPDB 62 6e-10 4DS7-A nrPDB 62 7e-10 2LC5-A nrPDB 62 9e-10 4JWQ-A nrPDB 62 1e-09 1LKJ-A nrPDB 61 1e-09 3O4Y-A nrPDB 60 5e-09 3HZT-A nrPDB 59 6e-09 3SIA-A nrPDB 59 7e-09 1IJ5-A nrPDB 58 1e-08 2AMI-A nrPDB 58 2e-08 2LAP-A nrPDB 57 2e-08 4RGJ-A nrPDB 57 2e-08 3FWC-A nrPDB 57 3e-08 3KHE-A nrPDB 57 3e-08 5JN2-A nrPDB 57 4e-08 3Q5I-A nrPDB 56 5e-08 5OTJ-D nrPDB 55 7e-08 5H7D-E nrPDB 55 8e-08 3K21-A nrPDB 55 9e-08 5B8I-B nrPDB 55 1e-07 4YZB-A nrPDB 55 1e-07 2LVK-A nrPDB 55 1e-07 2M29-A nrPDB 54 2e-07 2BL0-C nrPDB 54 2e-07 1SR6-C nrPDB 54 2e-07 4ZCV-A nrPDB 53 3e-07 2I08-A nrPDB 53 3e-07 2LHH-A nrPDB 53 4e-07 5JOJ-A nrPDB 53 4e-07 5COC-A nrPDB 53 4e-07 4ORC-B nrPDB 53 5e-07 4N5X-A nrPDB 53 5e-07 2HF5-A nrPDB 53 6e-07 2OPO-A nrPDB 52 9e-07 2LV7-A nrPDB 52 9e-07 3E3R-A nrPDB 52 1e-06 4Q57-A nrPDB 52 1e-06 3LIJ-A nrPDB 51 2e-06 3IFK-A nrPDB 51 2e-06 5JOL-A nrPDB 51 2e-06 2JOJ-A nrPDB 51 2e-06 2B1U-A nrPDB 50 3e-06 2ROB-A nrPDB 50 3e-06 2RO8-A nrPDB 50 3e-06 2KN2-A nrPDB 50 3e-06 4WPX-A nrPDB 50 4e-06 5Z1Q-A nrPDB 50 4e-06 3MSE-B nrPDB 50 5e-06 2M5E-A nrPDB 49 5e-06 2RO9-A nrPDB 49 6e-06 1FW4-A nrPDB 49 8e-06 2JNX-A nrPDB 48 1e-05 1ZMZ-A nrPDB 48 1e-05 2N7L-C nrPDB 47 2e-05 6MI5-X nrPDB 47 2e-05 1QX2-A nrPDB 47 3e-05 1JFJ-A nrPDB 47 3e-05 2KSZ-A nrPDB 47 3e-05 5VLN-A nrPDB 47 3e-05 3L19-A nrPDB 47 3e-05 1W7I-B nrPDB 46 4e-05 1H4B-A nrPDB 46 5e-05 1GGW-A nrPDB 46 5e-05 3JAX-C nrPDB 46 5e-05 2KZ2-A nrPDB 46 6e-05 5H53-B nrPDB 46 6e-05 2GGZ-A nrPDB 46 6e-05 5H53-C nrPDB 45 9e-05 4GJF-A nrPDB 45 1e-04 2K7C-A nrPDB 45 1e-04 5MWC-D nrPDB 45 1e-04 1O1A-B nrPDB 45 1e-04 2K7B-A nrPDB 45 1e-04 1I84-U nrPDB 45 2e-04 2G9B-A nrPDB 44 2e-04 1TRF-A nrPDB 44 2e-04 2ZFD-A nrPDB 44 3e-04 1TNP-A nrPDB 44 3e-04 5T7C-A nrPDB 44 3e-04 3I5I-C nrPDB 43 3e-04 2BL0-B nrPDB 43 3e-04 3TZ1-A nrPDB 43 3e-04 1F55-A nrPDB 43 4e-04 1UHN-A nrPDB 43 4e-04 3JBH-C nrPDB 43 5e-04 5TBY-E nrPDB 43 5e-04 2JNF-A nrPDB 42 7e-04 5M6C-E nrPDB 42 7e-04 4D1E-A nrPDB 42 7e-04 3I5H-B nrPDB 42 8e-04 2M8U-A nrPDB 42 9e-04 1JC2-A nrPDB 42 9e-04 2QFE-A nrPDB 42 9e-04 2JUL-A nrPDB 42 0.001 2LCP-A nrPDB 42 0.001 2Q4U-A nrPDB 42 0.001 5ZOR-A nrPDB 42 0.001 5TBY-C nrPDB 42 0.001 2W4G-C nrPDB 42 0.001 1BJF-A nrPDB 41 0.002 4P5W-A nrPDB 41 0.002 1OZS-A nrPDB 41 0.002 6FSA-D nrPDB 41 0.002 2PMY-A nrPDB 41 0.002 2LVV-A nrPDB 41 0.002 2E30-A nrPDB 41 0.002 2M97-A nrPDB 41 0.002 2L2E-A nrPDB 40 0.002 2BEC-A nrPDB 40 0.004 2JU0-A nrPDB 40 0.004 1N2D-A nrPDB 40 0.004 3DTP-E nrPDB 40 0.005 5I2L-A nrPDB 39 0.006 5PAL-A nrPDB 39 0.007 3J04-B nrPDB 39 0.008 2N8Y-A nrPDB 38 0.009 2I94-A nrPDB 38 0.010 5ZGM-A nrPDB 38 0.011 1SJJ-A nrPDB 38 0.011 2OS8-B nrPDB 38 0.019 1DGU-A nrPDB 37 0.026 1ZFS-A nrPDB 37 0.026 2LM5-A nrPDB 37 0.027 3PAT-A nrPDB 37 0.029 1S36-A nrPDB 37 0.031 1QLS-A nrPDB 37 0.031 1JF0-A nrPDB 37 0.031 2NLN-A nrPDB 37 0.034 1NYA-A nrPDB 37 0.039 3TS5-B nrPDB 36 0.061 6EPA-A nrPDB 36 0.062 3DD4-A nrPDB 36 0.066 3KPX-A nrPDB 36 0.067 2KYF-A nrPDB 36 0.067 2EC6-B nrPDB 36 0.073 1TTX-A nrPDB 36 0.074 1JBA-A nrPDB 35 0.081 4I5L-B nrPDB 35 0.090 1C7W-A nrPDB 35 0.092 1YIO-A nrPDB 35 0.10 5B7X-A nrPDB 35 0.11 1DFK-Y nrPDB 35 0.11 1NSH-A nrPDB 35 0.11 1B7T-Y nrPDB 35 0.11 5XOP-A nrPDB 35 0.12 1RTP-1 nrPDB 35 0.13 2LUC-A nrPDB 35 0.13 2FCE-A nrPDB 35 0.15 5VE9-A nrPDB 35 0.17 1G33-A nrPDB 35 0.17 5W1A-B nrPDB 34 0.18 2D8N-A nrPDB 34 0.18 1CB1-A nrPDB 34 0.23 5ZH6-A nrPDB 34 0.23 1V1G-A nrPDB 34 0.25 5XND-A nrPDB 34 0.26 2L0P-A nrPDB 34 0.27 2K2A-A nrPDB 33 0.32 2KQY-A nrPDB 33 0.34 3GMC-A nrPDB 33 0.36 1SL8-A nrPDB 33 0.38 5CPV-A nrPDB 33 0.40 4OCI-A nrPDB 33 0.45 1UHK-A nrPDB 33 0.49 2AUC-A nrPDB 33 0.50 2QJ0-A nrPDB 33 0.53 1RK9-A nrPDB 33 0.53 1KQV-A nrPDB 33 0.56 2M7M-A nrPDB 33 0.58 2I18-A nrPDB 33 0.58 1TIZ-A nrPDB 33 0.58 6AGH-A nrPDB 32 0.66 3CS1-A nrPDB 32 0.68 3AKA-A nrPDB 32 0.77 4MEW-A nrPDB 32 0.79 2NA0-A nrPDB 32 0.88 3HB6-A nrPDB 32 0.99 1A75-A nrPDB 32 1.2 4RI0-A nrPDB 32 1.3 4PAL-A nrPDB 32 1.3 4NQG-A nrPDB 31 1.5 2MBX-A nrPDB 31 1.6 1M39-A nrPDB 31 1.6 3AQL-A nrPDB 31 1.7 1BU3-A nrPDB 31 2.2 1YX7-A nrPDB 31 2.4 4I5K-A nrPDB 31 2.5 2K2I-A nrPDB 31 2.5 2NCO-A nrPDB 30 2.7 6EAZ-A nrPDB 30 2.9 2Y5I-A nrPDB 30 3.3 2MA2-A nrPDB 30 3.4 6AGI-A nrPDB 30 3.5 2M7L-A nrPDB 30 4.7 5NRK-B nrPDB 30 4.8 5JXU-A nrPDB 30 5.4 6ED3-A nrPDB 30 5.4 5LCW-N nrPDB 29 6.1 4PCW-A nrPDB 29 6.1 5CSF-A nrPDB 29 6.2 2M1U-A nrPDB 29 9.2 1BOD-A nrPDB 28 9.5 >1KFU-L nrPDB Length = 699 Score = 1317 bits (3408), Expect = 0.0, Method: Composition-based stats. Identities = 695/699 (99%), Positives = 697/699 (99%) Query: 2 AGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 61 AGIAAKLAKDREAAEGLGSH+RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK Sbjct: 1 AGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 60 Query: 62 ELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 121 ELGPYSSKTRG+ WKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL Sbjct: 61 ELGPYSSKTRGMRWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 120 Query: 122 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 181 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL Sbjct: 121 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 180 Query: 182 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 241 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS Sbjct: 181 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 240 Query: 242 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 301 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC Sbjct: 241 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 300 Query: 302 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 361 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM Sbjct: 301 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 360 Query: 362 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 421 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK Sbjct: 361 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 420 Query: 422 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 481 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE Sbjct: 421 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 480 Query: 482 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQL 541 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDG RRLFAQL Sbjct: 481 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL 540 Query: 542 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 601 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW Sbjct: 541 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 600 Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 661 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN Sbjct: 601 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 660 Query: 662 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL Sbjct: 661 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 699 >3DF0-A nrPDB Length = 714 Score = 1261 bits (3264), Expect = 0.0, Method: Composition-based stats. Identities = 655/700 (93%), Positives = 681/700 (97%) Query: 1 MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF 60 MAGIA KLAKDREAAEGLGSH+RAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEI Sbjct: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEI 120 Query: 121 LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 LARVVPL+QSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL Sbjct: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC 240 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGC Sbjct: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 Query: 241 SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN 300 SIDITSAADSEA+T+QKLVKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDN Sbjct: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 Query: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK 360 CPSWNT+DPE R LT R EDGEFWMSFSDFLRHYSRLEICNLTPDTLT D+YKKWKLTK Sbjct: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR 420 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDED+EDGE GCTFLVGLIQKHRRRQR Sbjct: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 Query: 421 KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG 480 KMGEDMHTIGFGIYEVPEEL+GQTNIHLSKNFFLT RARERSDTFINLREVLNRFKLPPG Sbjct: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 Query: 481 EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ 540 EY+LVPSTFEP+K+GDFCIRVFSEKKADYQ VDDEIEAN+EE + +E+DI DGFRRLFAQ Sbjct: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 LAGEDAEISAFELQTILRRVLAKR+DIKSDGFSIETCKIMVDMLD DGSGKLGLKEFYIL Sbjct: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD 660 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK+PCQLHQVIVARFADD+LIIDFD Sbjct: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 Query: 661 NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 NFVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 >1QXP-A nrPDB Length = 900 Score = 1219 bits (3153), Expect = 0.0, Method: Composition-based stats. Identities = 488/703 (69%), Positives = 592/703 (84%), Gaps = 4/703 (0%) Query: 1 MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF 60 MAGIA KLAKDREAAEGLGSH+RAIKYLNQDYE LRNECLEAG LFQDP+FP + +LGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPAFPPVSHSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGP SSKT GI+WKRPTE+ ++PQFI+ GATRTDICQGALGD WLLAAIASLTLNE I Sbjct: 61 KELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETI 120 Query: 121 LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 L RVVP QSFQE YAGIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSAL Sbjct: 121 LHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC 240 LEKAYAK+NG YEALSGG T+E FEDFTGG+ EWY+L+K P +L++II KAL++GSLLGC Sbjct: 181 LEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGC 240 Query: 241 SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN 300 SI+I+ D EAITF+ LV+GHAYSVT A++V G LIR+RNPWGEVEW G W+DN Sbjct: 241 SINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDN 300 Query: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK 360 WN +DP ERE+L + EDGEFWMSF DF+R +++LEICNLTPD L S T + W T Sbjct: 301 SYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLRNWNTTF 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED--EDEEDGESGCTFLVGLIQKHRRR 418 +G WRRGSTAGGCRNYP TFW+NPQ+ I+LEE D +D + ESGC+FL+ L+QKHRRR Sbjct: 361 YEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDSRESGCSFLLALMQKHRRR 420 Query: 419 QRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLP 478 +R+ G DM TIGF +Y+VP EL+GQ +HL ++FFL N +R +S+ FINLREV NR +LP Sbjct: 421 ERRFGRDMETIGFAVYQVPRELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLP 479 Query: 479 PGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANL-EEFDISEDDIDDGFRRL 537 PGEYI+VPSTFEPNK+GDF +R FSEKKA Q +DD+I+ANL +E +SE++IDD F+ L Sbjct: 480 PGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTL 539 Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 F++LAG+D EIS ELQTIL R+++K +D++++GFS+E+C+ MV+++D DG+GKLGL EF Sbjct: 540 FSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 ILW +I+ Y I+R+ D+D+SG+M++YEMR A+E AGFK+PCQLHQVIVARFADD+LII Sbjct: 600 NILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELII 659 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 DFDNFVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 660 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 702 Score = 268 bits (685), Expect = 6e-72, Method: Composition-based stats. Identities = 78/177 (44%), Positives = 122/177 (68%) Query: 523 FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 + +E + + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 722 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 781 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 ++DSD +GKLG +EF LW I+K+Q IY+ + DRSGT+ S E+ A E AGF + + Sbjct: 782 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHI 841 Query: 643 HQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG I++++ WL ++ Sbjct: 842 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 898 >1MDW-A nrPDB Length = 328 Score = 649 bits (1674), Expect = 0.0, Method: Composition-based stats. Identities = 308/328 (93%), Positives = 320/328 (97%) Query: 19 GSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRP 78 GSH+RAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGFKELGPYSSKTRGIEWKRP Sbjct: 1 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 60 Query: 79 TEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGI 138 TEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEILARVVPL+QSFQENYAGI Sbjct: 61 TEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 120 Query: 139 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 198 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG Sbjct: 121 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 180 Query: 199 ATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKL 258 ATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGCSIDITSAADSEA+T+QKL Sbjct: 181 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 240 Query: 259 VKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRR 318 VKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDNCPSWNT+DPE R LT R Sbjct: 241 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 300 Query: 319 HEDGEFWMSFSDFLRHYSRLEICNLTPD 346 EDGEFWMSFSDFLRHYSRLEICNLTPD Sbjct: 301 QEDGEFWMSFSDFLRHYSRLEICNLTPD 328 >2NQG-A nrPDB Length = 339 Score = 634 bits (1636), Expect = 0.0, Method: Composition-based stats. Identities = 234/330 (70%), Positives = 275/330 (83%) Query: 17 GLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWK 76 GLG H+ AIKYL QDYE LR CL+ G LFQD +FP + +LGFKELGP SSKT GI+WK Sbjct: 2 GLGRHENAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWK 61 Query: 77 RPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYA 136 RPTE+ ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLNE IL RVVP QSFQE YA Sbjct: 62 RPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYA 121 Query: 137 GIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALS 196 GIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSALLEKAYAK+NG YEALS Sbjct: 122 GIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALS 181 Query: 197 GGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQ 256 GG T+E FEDFTGG+ EWY+L+K P +L++II KAL++GSLLGCSI+I+ D EAITF+ Sbjct: 182 GGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFK 241 Query: 257 KLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLT 316 LV+GHAYSVT A++V G LIR+RNPWGEVEW G W+DN WN +DP ERE+L Sbjct: 242 NLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLR 301 Query: 317 RRHEDGEFWMSFSDFLRHYSRLEICNLTPD 346 + EDGEFWMSF DF+R +++LEICNLTPD Sbjct: 302 VKMEDGEFWMSFRDFIREFTKLEICNLTPD 331 >1ZCM-A nrPDB Length = 321 Score = 613 bits (1581), Expect = e-176, Method: Composition-based stats. Identities = 229/321 (71%), Positives = 274/321 (85%) Query: 23 RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEIC 82 AIKYL QDYE LR CL++GTLF+D +FP +P +LG+K+LGP SSKT GI+WKRPTE+ Sbjct: 1 NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELL 60 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQ 142 ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLN+ +L RVVP QSFQ YAGIFHFQ Sbjct: 61 SNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQ 120 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 WQ+GEWV+VVVDD LP KDG+L+FVHSAEG+EFWSALLEKAYAK+NG YEALSGG+T+E Sbjct: 121 LWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSE 180 Query: 203 GFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGH 262 FEDFTGG+ EWYEL+K P +L++II KAL++GSLLGCSIDI+S D EAITF+KLVKGH Sbjct: 181 AFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGH 240 Query: 263 AYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDG 322 AYSVTGA++V G + LIR+RNPWGEVEWTG W+D+ WN +DP ER++L + EDG Sbjct: 241 AYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDG 300 Query: 323 EFWMSFSDFLRHYSRLEICNL 343 EFWMSF DF+R ++RLEICNL Sbjct: 301 EFWMSFRDFMREFTRLEICNL 321 >2NQA-A nrPDB Length = 326 Score = 609 bits (1570), Expect = e-174, Method: Composition-based stats. Identities = 239/324 (73%), Positives = 283/324 (87%) Query: 23 RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEIC 82 A+KYL QD++ LR +CL++G LF+DP FPA PSALG+K+LGP S +T+GI WKRPTE+C Sbjct: 3 NALKYLGQDFKTLRQQCLDSGVLFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELC 62 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQ 142 PQFI+GGATRTDICQG LGDCWLLAAIASLTLNEE+L RVVP +Q FQENYAGIFHFQ Sbjct: 63 PSPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFHFQ 122 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQYGEWVEVV+DDRLPTK+G+LLF+HS +G+EFWSALLEKAYAK+NGCYEAL+GG+T E Sbjct: 123 FWQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVE 182 Query: 203 GFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGH 262 GFEDFTGGI+E+Y+LKKPP NL++II+KAL GSLLGCSID+ SAA++EAIT QKLVK H Sbjct: 183 GFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCSIDVYSAAEAEAITSQKLVKSH 242 Query: 263 AYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDG 322 AYSVTG EEV G +KLIR+RNPWGEVEW+G W+D+ P WN IDP +E L ++ EDG Sbjct: 243 AYSVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSDDAPEWNHIDPRRKEELDKKVEDG 302 Query: 323 EFWMSFSDFLRHYSRLEICNLTPD 346 EFWMS SDF+R +SRLEICNL+PD Sbjct: 303 EFWMSLSDFVRQFSRLEICNLSPD 326 >2P0R-A nrPDB Length = 333 Score = 552 bits (1423), Expect = e-157, Method: Composition-based stats. Identities = 191/326 (58%), Positives = 241/326 (73%), Gaps = 6/326 (1%) Query: 23 RAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEIC 82 R Q +E +R ECL+ GTLF+D FPA S+L + E WKRP EI Sbjct: 13 RITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSE-----RPQIPFVWKRPGEIV 67 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQ 142 +P+FI+GGATRTDICQG LGDCWLLAAIASLTLN++ LARV+P +QSF YAGIFHFQ Sbjct: 68 KNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQ 127 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQ+ EW++VV+DDRLPT L+F+HSA+ +EFWSALLEKAYAK+NG YEAL GG+ E Sbjct: 128 FWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIE 187 Query: 203 GFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGH 262 EDFTGG+AE ++ K+ P N ++I++KAL++GSLLGC ID SAA+SEA T L+KGH Sbjct: 188 AMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGH 247 Query: 263 AYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRH-ED 321 AYSVTG ++V G +LIRIRNPWG+VEW G W+D+ P W ++ P E++RL +D Sbjct: 248 AYSVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDD 307 Query: 322 GEFWMSFSDFLRHYSRLEICNLTPDT 347 GEFWM+F DF H+ ++EICNLTPD Sbjct: 308 GEFWMAFKDFKAHFDKVEICNLTPDA 333 >6BDT-A nrPDB Length = 382 Score = 521 bits (1342), Expect = e-148, Method: Composition-based stats. Identities = 176/366 (48%), Positives = 232/366 (63%), Gaps = 54/366 (14%) Query: 30 QDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFII 89 + +E L +CLE L+ DP FP ++L + + P WKRP EIC +P+FII Sbjct: 14 KTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQ-----FVWKRPPEICENPRFII 68 Query: 90 GGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEW 149 GA RTDICQG LGD W LAAIA LTLN+ +L RV+P +QSF ENYAGIFHFQFW+YGEW Sbjct: 69 DGANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEW 128 Query: 150 VEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTG 209 V+VV+DD LPT + +L+F S +EFWSALLEKAYAK++G YEAL GG TTE EDFTG Sbjct: 129 VDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTG 188 Query: 210 GIAEWYELKKPPPNLFKIIQKALQKGSLLGCSID----ITSAADSEAITFQK-------- 257 G+AE++E++ P +++KI++KA+++GSL+GCSID +T + + Sbjct: 189 GVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRN 248 Query: 258 ------------------------------------LVKGHAYSVTGAEEVESNGSLQKL 281 LV+GHAYSVTG +EV G KL Sbjct: 249 MDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKL 308 Query: 282 IRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRR-HEDGEFWMSFSDFLRHYSRLEI 340 +R+RNPWG+VEW G W+D W+ +D +E+ RL + EDGEFWMS+ DF+ H+++LEI Sbjct: 309 VRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEI 368 Query: 341 CNLTPD 346 CNLT D Sbjct: 369 CNLTAD 374 >1KFX-S nrPDB Length = 184 Score = 270 bits (691), Expect = 1e-72, Method: Composition-based stats. Identities = 82/177 (46%), Positives = 124/177 (70%) Query: 523 FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 + +E + FRRLFAQLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 ++DSD +GKLG +EF LW I+++Q IY++ D DRSGT+ S E+ A E AGF + L Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHL 125 Query: 643 HQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ FK LD + TG I++++ WL ++ Sbjct: 126 YNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 182 >3BOW-B nrPDB Length = 184 Score = 269 bits (689), Expect = 2e-72, Method: Composition-based stats. Identities = 79/177 (44%), Positives = 122/177 (68%) Query: 523 FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 + +E + + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 ++DSD +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF + + Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 125 Query: 643 HQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG I++++ WL ++ Sbjct: 126 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 182 >4OKH-A nrPDB Length = 189 Score = 258 bits (660), Expect = 5e-69, Method: Composition-based stats. Identities = 79/173 (45%), Positives = 123/173 (71%) Query: 527 EDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 E + FR +F Q+AG+D EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D+ Sbjct: 7 ESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 66 Query: 587 DGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVI 646 DGSGKL L+EF+ LW KI+ +QKI++ D D+SGT+NSYEMR A+ +AGF + QL+ +I Sbjct: 67 DGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII 126 Query: 647 VARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 R+AD + IDFD+F+ C VRLE +F+ F D + G I+L+++ WL ++ Sbjct: 127 TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 179 >1NP8-A nrPDB Length = 159 Score = 243 bits (621), Expect = 2e-64, Method: Composition-based stats. Identities = 74/158 (46%), Positives = 111/158 (70%) Query: 523 FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 + +E + + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 2 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 61 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 ++DSD +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF + + Sbjct: 62 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 121 Query: 643 HQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLD 680 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD Sbjct: 122 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLD 159 >1F4Q-A nrPDB Length = 165 Score = 206 bits (525), Expect = 2e-53, Method: Composition-based stats. Identities = 53/162 (32%), Positives = 90/162 (55%), Gaps = 4/162 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 F+ +AG+D E+ A ELQ L + + FS+ETC+IM+ MLD D +GK+G F Sbjct: 6 FSAVAGQDGEVDAEELQRCLTQ---SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAF 62 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 LW + +++ + +D D SGT+ +E+R+A+ G+++ Q IV R++ + I Sbjct: 63 KELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIF 122 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 FD++V C V+L L FK+ D G+ + +L ++ Sbjct: 123 -FDDYVACCVKLRALTDFFKKRDHLQQGSADFIYDDFLQGTM 163 >1JUO-A nrPDB Length = 198 Score = 204 bits (520), Expect = 9e-53, Method: Composition-based stats. Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 4/168 (2%) Query: 529 DIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDG 588 D FA +AG+D +I A ELQ L + F++ETC++MV MLD D Sbjct: 30 QTQDPLYGYFAAVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDM 86 Query: 589 SGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA 648 SG +G EF LW + +++ + D DRSGT++ E++KAL GF++ Q I Sbjct: 87 SGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAK 146 Query: 649 RFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLC 696 R++ + I FD+++ C V+L L F++ D G + ++ Sbjct: 147 RYSTN-GKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQ 193 >5MRA-A nrPDB Length = 167 Score = 203 bits (517), Expect = 2e-52, Method: Composition-based stats. Identities = 53/159 (33%), Positives = 85/159 (53%), Gaps = 4/159 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 FA +AG+D +I A ELQ L + F++ETC++MV MLD D SG +G EF Sbjct: 8 FAAVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 64 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ + I Sbjct: 65 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTN-GKI 123 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLC 696 FD+++ C V+L L F++ D G + ++ Sbjct: 124 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQ 162 >1GJY-A nrPDB Length = 167 Score = 201 bits (510), Expect = 1e-51, Method: Composition-based stats. Identities = 53/159 (33%), Positives = 84/159 (52%), Gaps = 4/159 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 FA +AG+D +I A ELQ L + F++ETC++MV MLD D SG +G EF Sbjct: 8 FASVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 64 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLII 657 LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ I Sbjct: 65 KELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYST-SGKI 123 Query: 658 DFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLC 696 FD+++ C V+L L F++ D G + ++ Sbjct: 124 TFDDYIACCVKLRALTDSFRRRDSAQQGMVNFSYDDFIQ 162 >2I7A-A nrPDB Length = 174 Score = 179 bits (454), Expect = 4e-45, Method: Composition-based stats. Identities = 41/163 (25%), Positives = 83/163 (50%), Gaps = 8/163 (4%) Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 L ++I A +LQ +L + L D FS++ C+ +V +++ +G+L +EF L Sbjct: 14 LVPRGSDIDATQLQGLLNQELLTGP--PGDMFSLDECRSLVALMELKVNGRLDQEEFARL 71 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA----GFKMPCQLHQVIVARFADDQLI 656 W ++ YQ +++++ G + S ++ KA+E G + +L ++ R++D Sbjct: 72 WKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGR 130 Query: 657 IDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + F + V L+RLE + K F+ L + G + L + W+ + Sbjct: 131 VSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEMEWMSLVM 172 >3AAJ-A nrPDB Length = 167 Score = 159 bits (401), Expect = 5e-39, Method: Composition-based stats. Identities = 39/155 (25%), Positives = 75/155 (48%), Gaps = 10/155 (6%) Query: 544 EDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 IS ELQ L + F+ T + ++ M D + + EF +W Sbjct: 17 RSGVISDTELQQALS-------NGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKY 69 Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADD-QLIIDFDNF 662 I +Q ++R D D SG ++ E+++AL +G+++ Q H +++ +F + I FD+F Sbjct: 70 ITDWQNVFRTYDRDNSGMIDKNELKQAL--SGYRLSDQFHDILIRKFDRQGRGQIAFDDF 127 Query: 663 VRCLVRLETLFKIFKQLDPENTGTIELDLISWLCF 697 ++ + L+ L IF++ D + G I++ +L Sbjct: 128 IQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSM 162 >1Y1X-A nrPDB Length = 191 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 39/171 (22%), Positives = 75/171 (43%), Gaps = 10/171 (5%) Query: 531 DDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGS 589 + F + + IS EL L FS+ T + ++ M D + S Sbjct: 26 NQELMEWFRAVDTDGSGAISVPELNAALSSA--------GVPFSLATTEKLLHMYDKNHS 77 Query: 590 GKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR 649 G++ EF L I ++ +R+ D G ++S E+R AL +G+++ Q Q ++ + Sbjct: 78 GEITFDEFKDLHHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMRK 137 Query: 650 FADD-QLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSV 699 F + + FD++V + + + +F D E TG + +++ SV Sbjct: 138 FDRQRRGSLGFDDYVELSIFVCRVRNVFAFYDRERTGQVTFTFDTFIGGSV 188 >1S6I-A nrPDB Length = 188 Score = 99.3 bits (246), Expect = 5e-21, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 7/101 (6%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM-PCQLHQVIVARFADDQLIIDFDN 661 +I +++++ ID D SGT+ E++ L+ G ++ ++ ++ A D ID+ Sbjct: 8 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGE 67 Query: 662 FVRCLVRL------ETLFKIFKQLDPENTGTIELDLISWLC 696 F+ V L E L F D + +G I LD I C Sbjct: 68 FIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQAC 108 Score = 59.6 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 17/149 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE++I G + LF + ++ I+ EL+ L+RV ++ + K ++D Sbjct: 4 LSEEEIG-GLKELFKMIDTDNSGTITFDELKDGLKRVGSELME--------SEIKDLMDA 54 Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRKALEEAGFK 637 D D SG + EF + K ++ + D D SG + E+++A ++ G Sbjct: 55 ADIDKSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLD 114 Query: 638 MPCQLHQVIVARFADDQLIIDFDNFVRCL 666 + +I D+ ID+ F + Sbjct: 115 -DIHIDDMIKEIDQDNDGQIDYGEFAAMM 142 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 572 FSIETCKI--MVDMLDSDGSGKLGLKEFYILWTKIQK 606 F ++ I M+ +D D G++ EF + K + Sbjct: 111 FGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRKRKG 147 >3QRX-A nrPDB Length = 169 Score = 98.9 bits (245), Expect = 6e-21, Method: Composition-based stats. Identities = 38/150 (25%), Positives = 64/150 (42%), Gaps = 21/150 (14%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I A EL+ +R + GF E K M+ + Sbjct: 24 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMISEI 73 Query: 585 DSDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D DGSG + +EF + T ++ K +R D D SGT+ ++R+ +E G Sbjct: 74 DKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGEN 133 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + +L ++I +D ID D F+R + Sbjct: 134 LTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 Score = 66.6 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 13/120 (10%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 K +V G++GL E + Q+ ++ + D D SGT+++ E++ A+ GF+ Sbjct: 6 KTVVSARRDQKKGRVGLTE-----EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 60 Query: 638 -MPCQLHQVIVARFADDQLIIDFDNFVRCLV-------RLETLFKIFKQLDPENTGTIEL 689 ++ ++I D IDF+ F+ + E + K F+ D +N+GTI + Sbjct: 61 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITI 120 >4IL1-A nrPDB Length = 823 Score = 82.0 bits (201), Expect = 9e-16, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 92/213 (43%), Gaps = 48/213 (22%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + Q+ + M++ Sbjct: 5 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINE 55 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 56 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 115 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCLV---------------------------- 667 K+ ++ ++I D ++++ FV+ + Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDAD 175 Query: 668 RLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 ++ L K FK+LD +N+G+ L + ++ L Sbjct: 176 EIKRLGKRFKKLDLDNSGS--LSVEEFMSLPEL 206 Score = 65.0 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 41/197 (20%), Positives = 77/197 (39%), Gaps = 49/197 (24%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 82 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 130 Query: 586 SDGSGKLGLKEFYILWT----------------------------KIQKYQKIYREIDVD 617 DG G++ +EF + T +I++ K ++++D+D Sbjct: 131 IDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLD 190 Query: 618 RSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRL-------E 670 SG+++ E E + + +VI D +DF F+ + + + Sbjct: 191 NSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ 247 Query: 671 TLFKIFKQLDPENTGTI 687 L F+ D + G I Sbjct: 248 KLRFAFRIYDMDKDGYI 264 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 28/145 (19%) Query: 546 AEISAFELQTILRRVLAKRQDIKSDG-FSIET------------CKIMVDMLDSDGSGKL 592 + A E++ + +R K+ D+ + G S+E + ++D+ D+DG+G++ Sbjct: 170 SHFDADEIKRLGKRF--KKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 227 Query: 593 GLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKMPC-QLH 643 KEF ++ QK + +R D+D+ G +++ E+ + L+ G + QL Sbjct: 228 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 287 Query: 644 QV----IVARFADDQLIIDFDNFVR 664 Q+ I+ D I F+ F Sbjct: 288 QIVDKTIINADKDGDGRISFEEFCA 312 >2AAO-A nrPDB Length = 166 Score = 81.6 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDN 661 +I ++++ ID D+SG + E++ L+ G + ++ ++ A D+ ID+ Sbjct: 25 EIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKE 84 Query: 662 FVRCLVRL------ETLFKIFKQLDPENTGTIELDLISWLC 696 F+ + L + LF F D + +G I D + C Sbjct: 85 FIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQAC 125 Score = 62.3 bits (150), Expect = 6e-10, Method: Composition-based stats. Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%) Query: 525 ISEDDIDDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE++I G + +F + A + +I+ EL+ L+RV G +++ +I+ M Sbjct: 21 LSEEEIA-GLKEMFNMIDADKSGQITFEELKAGLKRV----------GANLKESEILDLM 69 Query: 584 --LDSDGSGKLGLKEF--YILW-TKIQ---KYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 D D SG + KEF L KI+ + D D SG + E+++A EE G Sbjct: 70 QAADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFG 129 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 + ++ +++ D+ ID++ FV + Sbjct: 130 VE-DVRIEELMRDVDQDNDGRIDYNEFVAMM 159 >3KF9-A nrPDB Length = 149 Score = 80.8 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 21/150 (14%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I A EL+ +R + GF E K M+ + Sbjct: 4 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMIADI 53 Query: 585 DSDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D DGSG + +EF + T ++ K +R D D +G ++ +++ +E G Sbjct: 54 DKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGEN 113 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 M +L ++I D ++ + F R + Sbjct: 114 MTDEELQEMIDEADRDGDGEVNEEEFFRIM 143 Score = 63.1 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D SGT+++ E++ A+ GF+ ++ ++I D IDF+ F+ Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFL 67 Query: 664 RCLV-------RLETLFKIFKQLDPENTGTIEL 689 + + E + K F+ D + TG I Sbjct: 68 QMMTAKMGERDSREEIMKAFRLFDDDETGKISF 100 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 12/96 (12%) Query: 508 DYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDI 567 D++ + A + E D S ++I FR LF E +IS L+ + + + D Sbjct: 62 DFEEFLQMMTAKMGERD-SREEIMKAFR-LFDD--DETGKISFKNLKRVAKELGENMTD- 116 Query: 568 KSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 E + M+D D DG G++ +EF+ + K Sbjct: 117 -------EELQEMIDEADRDGDGEVNEEEFFRIMKK 145 >3EK4-A nrPDB Length = 451 Score = 80.8 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 87/186 (46%), Gaps = 23/186 (12%) Query: 494 DGDFCIRVFSEKKADYQA----VDDEIEANLEEFDISEDDIDDGFRRLFAQLAGE-DAEI 548 +GD + K D++ + ++E N + ++E+ I + F+ F+ + D I Sbjct: 273 EGDTLVNRIELKGIDFKEDGNILGHKLEYNTRD-QLTEEQIAE-FKEAFSLFDKDGDGTI 330 Query: 549 SAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI---- 604 + EL T++ R L + + + M++ +D+DG+G + EF + + Sbjct: 331 TTKELGTVM-RSLGQNP-------TEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT 382 Query: 605 ---QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFD 660 ++ ++ +R D D +G +++ E+R + G K+ ++ ++I D ++++ Sbjct: 383 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 442 Query: 661 NFVRCL 666 FV+ + Sbjct: 443 EFVQMM 448 Score = 72.7 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 60/150 (40%), Gaps = 21/150 (14%) Query: 551 FELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKI 610 FE T++ R+ K D K DG I+ L+ + +L ++ I ++++ Sbjct: 272 FEGDTLVNRIELKGIDFKEDG------NILGHKLEYNTRDQLTEEQ-------IAEFKEA 318 Query: 611 YREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLVRL 669 + D D GT+ + E+ + G +L +I AD IDF F+ + R Sbjct: 319 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 378 Query: 670 -------ETLFKIFKQLDPENTGTIELDLI 692 E + + F+ D + G I + Sbjct: 379 MKDTDSEEEIREAFRVFDKDGNGYISAAEL 408 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 41/182 (22%), Positives = 76/182 (41%), Gaps = 21/182 (11%) Query: 422 MGEDMHTIGFGI-YEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG 480 ED + +G + Y ++L+ + + F L ++ + + T L V+ P Sbjct: 288 FKEDGNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT 347 Query: 481 EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ 540 E L E + DG+ I D+ + +++ D SE++I + FR +F + Sbjct: 348 EAELQDMINEVDADGNGTI--------DFPEFLTMMARKMKDTD-SEEEIREAFR-VFDK 397 Query: 541 LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 + ISA EL+ ++ + K D E M+ D DG G++ +EF + Sbjct: 398 --DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQM 447 Query: 601 WT 602 T Sbjct: 448 MT 449 >3U0K-A nrPDB Length = 442 Score = 77.4 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 34/175 (19%), Positives = 80/175 (45%), Gaps = 27/175 (15%) Query: 501 VFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRR 559 V +K ++ D+ ++E+ I + F+ F+ + D I+ EL T++ R Sbjct: 283 VMQKKTKGWEPTRDQ---------LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVM-R 331 Query: 560 VLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYR 612 L + + + M++ +D+DG G + EF I+ + ++ ++ +R Sbjct: 332 SLGQNP-------TEAELQDMINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFR 384 Query: 613 EIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 D D +G +++ E+R + G K+ ++ ++I D ++++ FV+ + Sbjct: 385 VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 303 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEF 362 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 363 LIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 399 Score = 38.8 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 375 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 423 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 424 IDGDGQVNYEEFVQMMT 440 >2GGM-A nrPDB Length = 172 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 60/150 (40%), Gaps = 21/150 (14%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I EL+ +R + GF E K M+ + Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 76 Query: 585 DSDGSGKLGLKEFYILWTK-------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D +G+GK+ +F + T+ ++ K ++ D D +G ++ +++ +E G Sbjct: 77 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 136 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + +L ++I D + F+R + Sbjct: 137 LTDEELQEMIDEADRDGDGEVSEQEFLRIM 166 Score = 56.6 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D +GT++ E++ A+ GF+ ++ ++I + ++F +F+ Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFL 90 Query: 664 RCLVR-------LETLFKIFKQLDPENTGTIEL 689 + + E + K FK D + TG I Sbjct: 91 TVMTQKMSEKDTKEEILKAFKLFDDDETGKISF 123 Score = 31.9 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 97 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMIDE 148 Query: 584 LDSDGSGKLGLKEFYILWTK 603 D DG G++ +EF + K Sbjct: 149 ADRDGDGEVSEQEFLRIMKK 168 >1GGZ-A nrPDB Length = 148 Score = 76.6 bits (187), Expect = 4e-14, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 72/152 (47%), Gaps = 18/152 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ + + F+ F+ + D I+ EL T++R + + + M+ Sbjct: 4 LTEEQVTE-FKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTE--------AELRDMMSE 54 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 55 IDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGE 114 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCLV 667 K+ ++ ++I A D ++++ FVR LV Sbjct: 115 KLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 146 Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 37/97 (38%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 + ++++ + D D G + + E+ + G +L ++ D +DF F Sbjct: 9 VTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G + + Sbjct: 69 LGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAEL 105 >2L1W-A nrPDB Length = 149 Score = 76.6 bits (187), Expect = 4e-14, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 74/155 (47%), Gaps = 18/155 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I D F+ F + D I+ EL T++R + + E + M+ Sbjct: 4 LSEEQIVD-FKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISE 54 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF L K ++ ++ ++ D D++G +++ E+R + G Sbjct: 55 VDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGE 114 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCLVRLE 670 K+ ++ Q+I D ++++ FV+ ++ + Sbjct: 115 KLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTVR 149 Score = 58.9 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 36/97 (37%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNF 662 I +++ + D D G + E+ + +L +I AD I+FD F Sbjct: 9 IVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + + E L + FK D + G I + Sbjct: 69 LSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL 105 >4OY4-A nrPDB Length = 415 Score = 76.2 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 72/151 (47%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + Q+ + M++ Sbjct: 12 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINE 62 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 63 VDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 122 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 123 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEF 76 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 77 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 113 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 26/198 (13%) Query: 438 EELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDF 497 ++L+ + + F L ++ + + T L V+ P E L E + DGD Sbjct: 10 DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDG 69 Query: 498 CIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTIL 557 I D+ + +++ D SE++I + FR +F + + ISA EL+ ++ Sbjct: 70 TI--------DFPEFLTMMARKMKDTD-SEEEIREAFR-VFDK--DGNGYISAAELRHVM 117 Query: 558 RRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVD 617 + K D E M+ D DG G++ +EF + T + +K+Y Sbjct: 118 TNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYV----- 164 Query: 618 RSGTMNSYEMRKALEEAG 635 R G + ++ AL G Sbjct: 165 RDGVLTG-DIHMALLLEG 181 >5UKG-A nrPDB Length = 419 Score = 75.8 bits (185), Expect = 6e-14, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 68/151 (45%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + Q+ + M++ Sbjct: 275 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINE 325 Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG G EF + + Y+ + +R D D +G + + E+R + + G Sbjct: 326 VDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGE 385 Query: 637 KMPCQLHQVIVA-RFADDQLIIDFDNFVRCL 666 K+ + ++ D ++++ FV+ + Sbjct: 386 KLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD DF F Sbjct: 280 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEF 339 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 340 LTMMARKMSYRVTEEEIREAFRVFDKDGNGYI 371 Score = 37.3 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 11/78 (14%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 ++E++I + FR +F + + I A EL+ ++ + K D E M+ + Sbjct: 351 VTEEEIREAFR-VFDK--DGNGYIGAAELRHVMTDLGEKLTD--------EEVDEMIRVA 399 Query: 585 DSDGSGKLGLKEFYILWT 602 D DG G++ +EF + T Sbjct: 400 DIDGDGQVNYEEFVQMMT 417 >2OBH-A nrPDB Length = 143 Score = 75.4 bits (184), Expect = 7e-14, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 60/150 (40%), Gaps = 21/150 (14%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I EL+ +R + GF E K M+ + Sbjct: 2 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 51 Query: 585 DSDGSGKLGLKEFYILWTK-------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D +G+GK+ +F + T+ ++ K ++ D D +G ++ +++ +E G Sbjct: 52 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 111 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + +L ++I D + F+R + Sbjct: 112 LTDEELQEMIDEADRDGDGEVSEQEFLRIM 141 Score = 55.4 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D +GT++ E++ A+ GF+ ++ ++I + ++F +F+ Sbjct: 6 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFL 65 Query: 664 RCLVR-------LETLFKIFKQLDPENTGTIEL 689 + + E + K FK D + TG I Sbjct: 66 TVMTQKMSEKDTKEEILKAFKLFDDDETGKISF 98 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 72 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMIDE 123 Query: 584 LDSDGSGKLGLKEFYILWTK 603 D DG G++ +EF + K Sbjct: 124 ADRDGDGEVSEQEFLRIMKK 143 >1CLM-A nrPDB Length = 148 Score = 75.4 bits (184), Expect = 8e-14, Method: Composition-based stats. Identities = 35/153 (22%), Positives = 73/153 (47%), Gaps = 18/153 (11%) Query: 524 DISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 +++E+ I + F+ FA + D I+ EL T++R + + + M++ Sbjct: 3 ELTEEQIAE-FKEAFALFDKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMIN 53 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAG 635 +D+DG+G + EF L + K Q + ++ D D +G +++ E+R + G Sbjct: 54 EVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLG 113 Query: 636 FKMP-CQLHQVIVARFADDQLIIDFDNFVRCLV 667 K+ ++ ++I D I+++ FVR +V Sbjct: 114 EKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 146 Score = 63.1 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E L + FK D + G I + Sbjct: 69 LSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAEL 105 >4I2Y-A nrPDB Length = 421 Score = 75.1 bits (183), Expect = 1e-13, Method: Composition-based stats. Identities = 33/175 (18%), Positives = 77/175 (44%), Gaps = 27/175 (15%) Query: 501 VFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRR 559 V +K ++A D+ ++E+ I + F+ F+ + D I+ EL T++ R Sbjct: 262 VMQKKTMGWEATRDQ---------LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVM-R 310 Query: 560 VLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYR 612 L + + + M++ +D+DG G EF + + ++ ++ +R Sbjct: 311 SLGQNP-------TEAELQDMINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFR 363 Query: 613 EIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA-RFADDQLIIDFDNFVRCL 666 D D +G + + E+R + + G K+ + ++ D ++++ FV+ + Sbjct: 364 VFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 65.8 bits (159), Expect = 6e-11, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD DF F Sbjct: 282 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEF 341 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 342 LTMMARKMNDTDSEEEIREAFRVFDKDGNGYI 373 Score = 36.5 bits (83), Expect = 0.037, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + I A EL+ ++ + K D E M+ + D Sbjct: 354 SEEEIREAFR-VFDK--DGNGYIGAAELRHVMTDLGEKLTD--------EEVDEMIRVAD 402 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 403 IDGDGQVNYEEFVQMMT 419 >2F2P-A nrPDB Length = 179 Score = 74.7 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 73/151 (48%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + Q+ + M++ Sbjct: 5 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINE 55 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 56 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 115 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 106 Score = 36.9 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 82 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 130 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 131 IDGDGQVNYEEFVQMMT 147 >3WFN-B nrPDB Length = 182 Score = 74.7 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 73/151 (48%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + Q+ + M++ Sbjct: 11 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINE 61 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 62 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 121 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 122 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 16 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 75 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 76 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 112 Score = 36.9 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 11/81 (13%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 88 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 136 Query: 586 SDGSGKLGLKEFYILWTKIQK 606 DG G++ +EF + T Sbjct: 137 IDGDGQVNYEEFVQMMTAKGG 157 Score = 35.8 bits (81), Expect = 0.072, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 36/83 (43%), Gaps = 6/83 (7%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 88 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 147 Query: 627 MRKALEEAGFKMPCQLHQVIVAR 649 + + G ++ V++ R Sbjct: 148 FVQMMTAKGGGGGEEVSAVVLQR 170 >6O20-F nrPDB Length = 169 Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 73/151 (48%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++ R L + + + M++ Sbjct: 25 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVM-RSLGQNP-------TEAELQDMINE 75 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 76 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 135 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 136 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 30 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 89 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 90 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 126 Score = 36.9 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 102 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 150 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 151 IDGDGQVNYEEFVQMMT 167 >4E53-A nrPDB Length = 185 Score = 73.5 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 72/151 (47%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + + + M++ Sbjct: 12 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMINE 62 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 63 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 122 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 123 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 76 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 77 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 113 Score = 39.2 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 11/104 (10%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 89 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 137 Query: 586 SDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 DG G++ +EF + T +I G + +++ Sbjct: 138 IDGDGQVNYEEFVQMMTAKGGGGGAATKIQASFRGHITRKKLKG 181 >2N6A-A nrPDB Length = 173 Score = 73.1 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 71/150 (47%), Gaps = 18/150 (12%) Query: 526 SEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +E+ I + F+ F+ + D I+ EL T++R + + + M++ + Sbjct: 7 TEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMINEV 57 Query: 585 DSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G K Sbjct: 58 DADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 117 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + ++ ++I D ++++ FV+ + Sbjct: 118 LTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 11 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 70 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 71 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 107 Score = 36.5 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 83 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 131 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 132 IDGDGQVNYEEFVQMMT 148 >1DTL-A nrPDB Length = 161 Score = 73.1 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 76/172 (44%), Gaps = 24/172 (13%) Query: 512 VDDEIEANLEEFDISEDDIDDGFRRLFA--QLAGEDAEISAFELQTILRRVLAKRQDIKS 569 +DD +A +E+ ++ + F+ F L ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLT---EEQKNEFKAAFDIFVLGAEDGSISTKELGKVM-RMLGQNP---- 52 Query: 570 DGFSIETCKIMVDMLDSDGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRS 619 + E + M+D +D DGSG + EF ++ ++ ++R D + Sbjct: 53 ---TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNAD 109 Query: 620 GTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLVRLE 670 G ++ E++ L+ G + + +++ ++ ID+D F+ + +E Sbjct: 110 GYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE 161 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 11/88 (12%) Query: 619 SGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFVRCLVRL-------- 669 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGK 92 Query: 670 --ETLFKIFKQLDPENTGTIELDLISWL 695 E L +F+ D G I+L+ + + Sbjct: 93 SEEELSDLFRMFDKNADGYIDLEELKIM 120 >5I0I-E nrPDB Length = 145 Score = 73.1 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 75/152 (49%), Gaps = 20/152 (13%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAE--ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 ++E+ I + F+ F+ LA +D + I+ EL T++R + + + M++ Sbjct: 3 LTEEQIAE-FKEAFS-LADKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMIN 52 Query: 583 MLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 53 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 112 Query: 636 FKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 113 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 8 IAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 67 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 68 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 104 Score = 36.1 bits (82), Expect = 0.050, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 80 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 128 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 129 IDGDGQVNYEEFVQMMT 145 >5D43-A nrPDB Length = 178 Score = 72.4 bits (176), Expect = 6e-13, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 60/150 (40%), Gaps = 21/150 (14%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 +D R F + I EL+ +R + GF E K M+ + Sbjct: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL----------GFEPRKEEMKKMISEV 76 Query: 585 DSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D + +GK+ +F + T+ ++ K +R D D +G ++ +++ E G Sbjct: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES 136 Query: 638 MP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + +L ++I D ++ + F++ + Sbjct: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 Score = 59.6 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D SGT++ E++ A+ GF+ ++ ++I + I F++F+ Sbjct: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 Query: 664 RCLVR-------LETLFKIFKQLDPENTGTIEL 689 + + E + K F+ D + TG I Sbjct: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 Score = 36.1 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 47/128 (36%), Gaps = 26/128 (20%) Query: 489 FEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFD--------ISEDDIDDGFRRLFAQ 540 FEP K+ E K VD E + D ++E D + + F Sbjct: 62 FEPRKE---------EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRL 112 Query: 541 LAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYI 599 ++ +IS L+ + + + + E + M+D D DG G++ +EF Sbjct: 113 FDDDETGKISFKNLKRVANEL--------GESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 Query: 600 LWTKIQKY 607 + K Y Sbjct: 165 IMKKTNLY 172 >5A2H-A nrPDB Length = 149 Score = 72.4 bits (176), Expect = 7e-13, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 70/149 (46%), Gaps = 17/149 (11%) Query: 528 DDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 DD F+ F+ + D I+ EL T++R + + + M++ +D+ Sbjct: 7 DDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTE--------AELQDMINEVDA 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP 639 DG+G + EF L + ++ ++ +R D D++G +++ E+R + G K+ Sbjct: 59 DGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLT 118 Query: 640 -CQLHQVIVARFADDQLIIDFDNFVRCLV 667 ++ ++I D I+++ FV+ ++ Sbjct: 119 DEEVDEMIREADVDGDGQINYEEFVKVMM 147 Score = 60.4 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 38/97 (39%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D G + + E+ + G +L +I AD IDF F Sbjct: 10 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E L + F+ D + G I + Sbjct: 70 LNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAEL 106 >6HCS-A nrPDB Length = 167 Score = 72.0 bits (175), Expect = 9e-13, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 72/151 (47%), Gaps = 18/151 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + + + M++ Sbjct: 5 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMINE 55 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D+DG+G + EF + + ++ ++ +R D D +G +++ E+R + G Sbjct: 56 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGE 115 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ ++I D ++++ FV+ + Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 + + R E + + F+ D + G I + Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 106 Score = 35.4 bits (80), Expect = 0.094, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ + + K D E M+ D Sbjct: 82 SEEEIREAFR-VFDK--DGNGYISAAELRHFMTNLGEKLTD--------EEVDEMIREAD 130 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 131 IDGDGQVNYEEFVQMMT 147 >1S6J-A nrPDB Length = 87 Score = 70.4 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM-PCQLHQVIVARFADDQLIIDFDN 661 +I +++++ ID D SGT+ E++ L+ G ++ ++ ++ A D ID+ Sbjct: 21 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGE 80 Query: 662 FVRCLVR 668 F+ V Sbjct: 81 FIAATVH 87 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 10/74 (13%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE++I G + LF + ++ I+ EL+ L+RV ++ + K ++D Sbjct: 17 LSEEEIG-GLKELFKMIDTDNSGTITFDELKDGLKRVGSELME--------SEIKDLMDA 67 Query: 584 LDSDGSGKLGLKEF 597 D D SG + EF Sbjct: 68 ADIDKSGTIDYGEF 81 >2TN4-A nrPDB Length = 159 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 69/154 (44%), Gaps = 21/154 (13%) Query: 525 ISEDDIDDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I + F+ F + +IS EL T++R + + E +++ Sbjct: 11 LSEEMIAE-FKAAFDMFDADGGGDISVKELGTVMRMLGQTP--------TKEELDAIIEE 61 Query: 584 LDSDGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEE 633 +D DGSG + +EF ++ ++ +++R D + G +++ E+ + Sbjct: 62 VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRA 121 Query: 634 AGFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 +G + ++ ++ ++ IDFD F++ + Sbjct: 122 SGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 49.6 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 11/100 (11%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNF 662 I +++ + D D G ++ E+ + G + I+ D IDF+ F Sbjct: 16 IAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEF 75 Query: 663 VRCLVRL----------ETLFKIFKQLDPENTGTIELDLI 692 + +VR E L ++F+ D G I+ + + Sbjct: 76 LVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEEL 115 >1TOP-A nrPDB Length = 162 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 68/154 (44%), Gaps = 21/154 (13%) Query: 525 ISEDDIDDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I + F+ F + +IS EL T++ R+L + + E +++ Sbjct: 14 LSEEMIAE-FKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEE 64 Query: 584 LDSDGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEE 633 +D DGSG + +EF ++ ++ +R D + G ++ E+ + L Sbjct: 65 VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRA 124 Query: 634 AGFKMPCQ-LHQVIVARFADDQLIIDFDNFVRCL 666 G + + + ++ ++ IDFD F++ + Sbjct: 125 TGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 52.7 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 44/122 (36%), Gaps = 16/122 (13%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQ 641 M D + L E I +++ + D D G +++ E+ + G + Sbjct: 2 SMTDQQAEARAFLSE-----EMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKE 56 Query: 642 LHQVIVAR-FADDQLIIDFDNFVRCLVRL----------ETLFKIFKQLDPENTGTIELD 690 I+ D IDF+ F+ +VR E L F+ D G I+++ Sbjct: 57 ELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIE 116 Query: 691 LI 692 + Sbjct: 117 EL 118 >5E37-A nrPDB Length = 356 Score = 65.4 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 74/189 (39%), Gaps = 26/189 (13%) Query: 512 VDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 +DD +A +EE + RR + I EL+ +L + + + S Sbjct: 20 MDDASKAKMEELE----------RRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQH 69 Query: 572 FSIE-TCKIMVDMLDSDGSGKLGLKEFYI-------LWTKIQKYQKIYREIDVDRSGTMN 623 + E + ++ D + G + +EF L + +Y+ ++ +D +GT+ Sbjct: 70 WLPEDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIG 129 Query: 624 SYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPE 682 + E+ K G + +L ++ DD I+F F+ L+ +L + + Sbjct: 130 ATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFL--LMFRNSLLDL-----KD 182 Query: 683 NTGTIELDL 691 T + LD Sbjct: 183 MTTYMTLDE 191 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 49/115 (42%), Gaps = 17/115 (14%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG----FKMPC------QLHQVIVARFA 651 K+++ ++ ++ DVD +G ++ E+R LE + M +L + + Sbjct: 26 AKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDV 85 Query: 652 DDQLIIDFDNFVRCL---VRLETLF----KIFKQLDPENTGTIELDLISWLCFSV 699 + +I F+ F + + + LE FK +D GTI +S L S+ Sbjct: 86 NKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASL 140 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 27/163 (16%), Positives = 66/163 (40%), Gaps = 30/163 (18%) Query: 513 DDEIEANLEEFDISEDDID--DGFRRL-----------------FAQLAGED-AEISAFE 552 +DE+E +E++D+++D + + F+++ F + I A E Sbjct: 73 EDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATE 132 Query: 553 LQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW-TKIQKYQKIY 611 L + + + S+E ++ M D D SG++ EF +++ + + + Sbjct: 133 LSKLFASL--------GNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMT 184 Query: 612 REIDVDRSGTMNSYEMRKALE-EAGFKMPCQLHQVIVARFADD 653 + +D +G +S + A+E + + +++ D Sbjct: 185 TYMTLDEAGAGSSGSLVDAVEGDMTLIFSEEELDALISANPDK 227 >3NCG-A nrPDB Length = 486 Score = 65.0 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 14/152 (9%) Query: 529 DIDDGFRRLFAQL-AGEDAEISAFELQTILRRVL-AKRQD----IKSDGFSIE-TCKIMV 581 D +F +L D + EL + K D I+++G +IE ++ Sbjct: 328 DETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLM 387 Query: 582 DMLDSDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 +LD DGSG + EF + ++ ++ ++ D D SG +++ E+ K +A Sbjct: 388 PLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSQAD 447 Query: 636 FKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + +L +I + +DF+ FV L Sbjct: 448 SSIQMEELESIIEQVDNNKDGEVDFNEFVEML 479 Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 43/109 (39%), Gaps = 21/109 (19%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKA---------------LEEAGFKMPCQLHQVIVAR 649 ++ +I+R++D + G ++ E+ + ++ G + Q+ ++ Sbjct: 331 KQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLL 390 Query: 650 FADDQLIIDFDNFVR------CLVRLETLFKIFKQLDPENTGTIELDLI 692 D I++ F+ L+ E + + FK D + +G I + Sbjct: 391 DMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKEL 439 >2LMV-A nrPDB Length = 148 Score = 64.7 bits (156), Expect = 2e-10, Method: Composition-based stats. Identities = 27/148 (18%), Positives = 63/148 (42%), Gaps = 16/148 (10%) Query: 524 DISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +++E+ I + F+ F Q E A L R L + + + ++ Sbjct: 3 ELTEEQIAE-FKDAFVQFDKEGTGKIATRELGTLMRTLGQNP-------TEAELQDLIAE 54 Query: 584 LDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +++ +G+L EF + K ++ ++ ++ D D G ++ E+R + G Sbjct: 55 AENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGE 114 Query: 637 KMP-CQLHQVIVARFADDQLIIDFDNFV 663 K+ ++ ++I D +I+++ FV Sbjct: 115 KVTDEEIDEMIREADFDGDGMINYEEFV 142 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 40/100 (40%), Gaps = 8/100 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I +++ + + D + +G + + E+ + G +L +I ++ ++F F Sbjct: 9 IAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLISWL 695 + + E + + FK D + G I + ++ Sbjct: 69 CGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFV 108 >4MVF-A nrPDB Length = 506 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPCQLHQVIVARFADDQLIIDFDN 661 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + + Sbjct: 358 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 417 Query: 662 FVRCLVRLETLFKI------FKQLDPENTGTIELDLIS 693 F+ + +T K FK D + G I ++ + Sbjct: 418 FLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELK 455 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 60/149 (40%), Gaps = 18/149 (12%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 + R +F L +S+ E+ L+++ Q I D ++ +DS+ SG Sbjct: 360 NNLRNIFIALDVDNSGTLSSQEILDGLKKI--GYQKIPPD------IHQVLRDIDSNASG 411 Query: 591 KLGLKEFYILWTKIQKYQKI------YREIDVDRSGTMNSYEMRKALEEAGFK---MPCQ 641 ++ +F Q Y K ++ D+D +G ++ E+++ + + Sbjct: 412 QIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKA 471 Query: 642 LHQVIVARFADDQLIIDFDNFVRCLVRLE 670 + ++ + IDF F+ + +LE Sbjct: 472 IDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 >3PM8-A nrPDB Length = 197 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPCQLHQVIVARFADDQLIIDFDN 661 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + + Sbjct: 55 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 114 Query: 662 FVRCLVRLETLFKI------FKQLDPENTGTIELDLIS 693 F+ + +T K FK D + G I ++ + Sbjct: 115 FLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELK 152 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 56/142 (39%), Gaps = 18/142 (12%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 + R +F L +S+ E+ L+++ Q I D ++ +DS+ SG Sbjct: 57 NNLRNIFIALDVDNSGTLSSQEILDGLKKI--GYQKIPPD------IHQVLRDIDSNASG 108 Query: 591 KLGLKEFYILWTKIQKYQKI------YREIDVDRSGTMNSYEMRKALEEAGFK---MPCQ 641 ++ +F Q Y K ++ D+D +G ++ E+++ + + Sbjct: 109 QIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKA 168 Query: 642 LHQVIVARFADDQLIIDFDNFV 663 + ++ + IDF F+ Sbjct: 169 IDSLLQEVDLNGDGEIDFHEFM 190 Score = 34.2 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 27/59 (45%), Gaps = 6/59 (10%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 + +IS EL+ I +D + + ++ +D +G G++ EF ++ +K Sbjct: 143 NGKISVEELKRIF------GRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 >1OQP-A nrPDB Length = 77 Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDN 661 ++ K +R D D SGT+ ++R+ +E G + +L ++I +D ID D Sbjct: 7 SREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDE 66 Query: 662 FVRCL 666 F+R + Sbjct: 67 FIRIM 71 >2LHI-A nrPDB Length = 176 Score = 62.3 bits (150), Expect = 6e-10, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 22/157 (14%) Query: 518 ANLEEFDISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIET 576 +NL E I+E F+ FA ++ IS+ EL T++R + S Sbjct: 3 SNLTEEQIAE------FKEAFALFDKDNNGSISSSELATVMRSLGLSP--------SEAE 48 Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRK 629 +++ +D DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ Sbjct: 49 VNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKH 108 Query: 630 ALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 L G K+ ++ +D I+ F L Sbjct: 109 VLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALL 145 Score = 54.6 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 10 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 69 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + + R + L + FK D G I + + S+ Sbjct: 70 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 113 >4DS7-A nrPDB Length = 147 Score = 62.3 bits (150), Expect = 7e-10, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 64/151 (42%), Gaps = 17/151 (11%) Query: 524 DISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 +++E+ I + F+ FA ++ ISA EL T++R + S +++ Sbjct: 4 NLTEEQIAE-FKEAFALFDKDNSGSISASELATVMRSLGLSP--------SEAEVADLMN 54 Query: 583 MLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 +D DG+ + EF L ++ Q+ + ++ D + G +++ E++ L G Sbjct: 55 EIDVDGNHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG 114 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 K+ ++ +D I+ F L Sbjct: 115 EKLTDAEVDEMLREVSDGSGEINIKQFAALL 145 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D SG++++ E+ + G ++ ++ D I+F F Sbjct: 10 IAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHAIEFSEF 69 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + + R + L + FK D G I + + S+ Sbjct: 70 LALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 113 >2LC5-A nrPDB Length = 151 Score = 62.0 bits (149), Expect = 9e-10, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 64/153 (41%), Gaps = 16/153 (10%) Query: 521 EEFDISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKI 579 E+ + + ++ F + D +++A EL T++R + A K Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQK--------ISE 54 Query: 580 MVDMLDSDGSGKLGLKEFYILW-------TKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 +V D D SGK + F + + +K + D +++G +++ E++ L Sbjct: 55 IVKDYDKDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLT 114 Query: 633 EAGFKMPCQLHQVIVARFADDQLIIDFDNFVRC 665 G K+ Q ++ ++ +I+ D+FV+ Sbjct: 115 TLGEKLTEQEVDDLLKEIGVEEGLINVDDFVKL 147 Score = 47.7 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 37/97 (38%), Gaps = 8/97 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFA-DDQLIIDFDNFV 663 Q+Y++ ++ D D + + E+ + G Q IV + D+ D + F+ Sbjct: 14 QEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQETFL 73 Query: 664 RCLVR-------LETLFKIFKQLDPENTGTIELDLIS 693 ++ E + K F+ D E G I + Sbjct: 74 TIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELK 110 >4JWQ-A nrPDB Length = 199 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 +Q+ + ++ +D D G + +++K LE +G K+P ++ +D ID+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTIELDLISWL 695 + + L K F+ D +N G I ++ + Sbjct: 117 AAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHI 153 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 60/157 (38%), Gaps = 22/157 (14%) Query: 526 SEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 S D + +F L + I+ +L+ L K F + ++D + Sbjct: 52 SNDYDLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQ----NFDV-----LLDQI 102 Query: 585 DSDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKALEEAGFKMP 639 DSDGSG++ EF + K +R DVD G + + E+ L K Sbjct: 103 DSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGS 162 Query: 640 ------CQLHQVIVARFADDQLIIDFDNFVRCLVRLE 670 Q+ ++I ++ IDF F +++L+ Sbjct: 163 ITQKDVNQVKKMIQEVDKNNDGKIDFYEF-CEMMKLK 198 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 6/87 (6%) Query: 516 IEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIE 575 + A L+ +S+ I FR +F D EI+ EL IL K + D + Sbjct: 116 LAAALDRKHLSKKLIYCAFR-VFD--VDNDGEITTAELAHILYNGNKKGSITQKD---VN 169 Query: 576 TCKIMVDMLDSDGSGKLGLKEFYILWT 602 K M+ +D + GK+ EF + Sbjct: 170 QVKKMIQEVDKNNDGKIDFYEFCEMMK 196 >1LKJ-A nrPDB Length = 146 Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 22/157 (14%) Query: 518 ANLEEFDISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIET 576 +NL E I+E F+ FA ++ IS+ EL T++R + S Sbjct: 2 SNLTEEQIAE------FKEAFALFDKDNNGSISSSELATVMRSLGLSP--------SEAE 47 Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRK 629 +++ +D DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ Sbjct: 48 VNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKH 107 Query: 630 ALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 L G K+ ++ +D I+ F L Sbjct: 108 VLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALL 144 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + + R + L + FK D G I + + S+ Sbjct: 69 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 112 >3O4Y-A nrPDB Length = 196 Score = 59.6 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 +QK + + +D + G + ++RK LE +G +P ++ +D ID+ F+ Sbjct: 54 VQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTIELDLISWLCFS 698 + L K F+ D +N G I ++ + F+ Sbjct: 114 AAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFN 153 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Query: 516 IEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIE 575 + A ++ +S+ I FR +F D EI+ EL +L + + D + Sbjct: 113 LAAAIDRRQLSKKLIYCAFR-VFD--VDNDGEITTAELAHVLFNGNKRGNITERD---VN 166 Query: 576 TCKIMVDMLDSDGSGKLGLKEFYILWT 602 K M+ +D +G GK+ EF + Sbjct: 167 QVKKMIREVDKNGDGKIDFYEFSEMMK 193 >3HZT-A nrPDB Length = 467 Score = 59.3 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 65/155 (41%), Gaps = 13/155 (8%) Query: 529 DIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIE---TCKIMVDML 584 + ++F QL D ++ EL R+++ + D SD S + ++ + Sbjct: 311 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 370 Query: 585 DSDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 D D +G + EF L ++ +++ D D SG + + E+ + ++ Sbjct: 371 DFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EV 428 Query: 639 PCQL-HQVIVARFADDQLIIDFDNFVRCLVRLETL 672 + HQV+ ++ +DF+ FV + ++ + Sbjct: 429 DDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDV 463 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 44/102 (43%), Gaps = 18/102 (17%) Query: 605 QKYQKIYREIDVDRSGTMNSYEM----RKALEEAG--------FKMPCQLHQVIVARFAD 652 ++ +I+R++D + G ++ E+ RK ++ G ++ ++ ++ + D Sbjct: 314 KELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFD 373 Query: 653 DQLIIDFDNFVRCLV------RLETLFKIFKQLDPENTGTIE 688 I++ FV + E L F+Q D + +G I Sbjct: 374 RNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKIT 415 >3SIA-A nrPDB Length = 220 Score = 58.9 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 60/147 (40%), Gaps = 6/147 (4%) Query: 532 DGFRRLFAQLAGEDAEISAF-ELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D + R++ G D + S E+ ++ + S +T M+ + D+D +G Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRL-----SPQTALRMMRIFDTDFNG 102 Query: 591 KLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARF 650 + EF ++ ++ ++ RSGT+ +E+ AL++ GF + + ++ F Sbjct: 103 HISFYEFMAMYKFMELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRTSLLLHRLF 162 Query: 651 ADDQLIIDFDNFVRCLVRLETLFKIFK 677 A D + ++ ++ Sbjct: 163 ARGMAFCDLNCWIAICAFAAQTRSAYQ 189 >1IJ5-A nrPDB Length = 323 Score = 58.5 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 66/165 (40%), Gaps = 16/165 (9%) Query: 525 ISEDDIDDGFRRLF--AQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 +SE+D + R+LF + ++G + S +L+ +L + + K + Sbjct: 116 LSEEDTNI-LRQLFLSSAVSGS-GKFSFQDLKQVLAKYADTIPEGP--------LKKLFV 165 Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 M+++D G++ + + +R+ID + +GT++ E R+ GF Sbjct: 166 MVENDTKGRMSYITLVAVANDLAALVADFRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQ 225 Query: 643 HQVIVARFADDQLIIDFDNFVR---CLVRLETLFKIFKQLDPENT 684 + D+ + F +V CL+ L L+ F D Sbjct: 226 DALFRYADEDESDDVGFSEYVHLGLCLLVLRILY-AFADFDKSGQ 269 Score = 39.2 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%) Query: 585 DSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQ 644 D D S +G E+ L + + +Y D D+SG ++ E++K LE+A +P + Sbjct: 233 DEDESDDVGFSEYVHLGLCLLVLRILYAFADFDKSGQLSKEEVQKVLEDA--HIPESARK 290 Query: 645 VIVARFA----DDQLIIDFDNFV 663 +F+ DD + + FV Sbjct: 291 KFEHQFSVVDVDDSKSLSYQEFV 313 >2AMI-A nrPDB Length = 96 Score = 57.7 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 K +V G++GL E + Q+ ++ + D D SGT+++ E++ A+ GF+ Sbjct: 8 KTVVSARRDQKKGRVGLTE-----EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 62 Query: 638 -MPCQLHQVIVARFADDQLIIDFDNFVRCL 666 ++ ++I D IDF+ F+ + Sbjct: 63 PKKEEIKKMISEIDKDGSGTIDFEEFLTMM 92 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 13/78 (16%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I A EL+ +R + GF E K M+ + Sbjct: 26 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMISEI 75 Query: 585 DSDGSGKLGLKEFYILWT 602 D DGSG + +EF + T Sbjct: 76 DKDGSGTIDFEEFLTMMT 93 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 11/80 (13%) Query: 558 RRVLAKRQDIKSDGFSI-----ETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QK 606 + V++ R+D K + + + D+ D+DGSG + KE + + ++ Sbjct: 8 KTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEE 67 Query: 607 YQKIYREIDVDRSGTMNSYE 626 +K+ EID D SGT++ E Sbjct: 68 IKKMISEIDKDGSGTIDFEE 87 >2LAP-A nrPDB Length = 167 Score = 57.3 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 44/102 (43%), Gaps = 12/102 (11%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDN 661 +I++ ++ +RE D D+ G +N ++ + G+ +L ++ + +DFD+ Sbjct: 23 EIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDD 82 Query: 662 FVRC-----------LVRLETLFKIFKQLDPENTGTIELDLI 692 FV ++ ++ L F++ D G I + Sbjct: 83 FVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSEL 124 Score = 52.3 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 30/165 (18%), Positives = 69/165 (41%), Gaps = 23/165 (13%) Query: 519 NLEEFDIS-EDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIET 576 NL D S + + R F + + D I+ +L +R + + ++ IE Sbjct: 11 NLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGY----MPTEMELIE- 65 Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWT-----------KIQKYQKIYREIDVDRSGTMNSY 625 + ++ + G + +F L +++ + +RE D + G +++ Sbjct: 66 ---LSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTS 122 Query: 626 EMRKAL-EEAGFKM-PCQLHQVIVARFADDQLIIDFDNFVRCLVR 668 E+R+A+ + G ++ + ++I + +DF+ FVR + R Sbjct: 123 ELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >4RGJ-A nrPDB Length = 520 Score = 57.3 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 63/153 (41%), Gaps = 11/153 (7%) Query: 529 DIDDGFRRLFAQLAGE-DAEISAFELQTILRRVL-AKRQDIKS-DGFSIE-TCKIMVDML 584 D ++F ++ D ++ EL + +L K +D D +IE +++ + Sbjct: 368 DETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSI 427 Query: 585 DSDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 D D +G + EF L ++ +K ++ D D SG +++ E+ + + Sbjct: 428 DLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGLSDVSS 487 Query: 639 PCQLHQVIVARFADDQLIIDFDNFVRCLVRLET 671 C V+ ++ IDF F LV+L Sbjct: 488 EC-WKTVLKEVDQNNDGEIDFKEFRDMLVKLCN 519 Score = 49.6 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 18/109 (16%) Query: 605 QKYQKIYREIDVDRSGTMNSYEM----RKALEEAGFKMPC--------QLHQVIVARFAD 652 ++ KI++++D + G ++ E+ ++ L+ G ++ Q++ + D Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLD 430 Query: 653 DQLIIDFDNFV------RCLVRLETLFKIFKQLDPENTGTIELDLISWL 695 I++ F+ + L+ E L K FK D + +G I + ++ L Sbjct: 431 QNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQL 479 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 508 DYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDI 567 Y + + +++ + + + +LF + +ISA EL + Sbjct: 433 GYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDK--DGSGKISANELAQLF---------G 481 Query: 568 KSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKY 607 SD S E K ++ +D + G++ KEF + K+ Y Sbjct: 482 LSD-VSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLCNY 520 >3FWC-A nrPDB Length = 161 Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 50/110 (45%), Gaps = 10/110 (9%) Query: 567 IKSDGFSI--ETCKIMVDMLDSDGSGKLGLKEFYILWTK-------IQKYQKIYREIDVD 617 +K+ GF + ++D DS+G + +FYI+ + + + ++ ++ D D Sbjct: 49 MKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDD 108 Query: 618 RSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFA-DDQLIIDFDNFVRCL 666 +G ++ +R+ +E G + + + ++ F D I+ + F+ Sbjct: 109 HTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 49/93 (52%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 Q+ + + D++ G ++ +E++ A++ GF++P ++ +I ++ + ++ +D+F Sbjct: 23 QEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFY 82 Query: 664 RCLVR-------LETLFKIFKQLDPENTGTIEL 689 + L+ + + F+ D ++TG I + Sbjct: 83 IVMGEKILKRDPLDEIKRAFQLFDDDHTGKISI 115 >3KHE-A nrPDB Length = 191 Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 65/155 (41%), Gaps = 13/155 (8%) Query: 529 DIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIE---TCKIMVDML 584 + ++F QL D ++ EL R+++ + D SD S + ++ + Sbjct: 37 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 96 Query: 585 DSDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 D D +G + EF L ++ +++ D D SG + + E+ + ++ Sbjct: 97 DFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EV 154 Query: 639 PCQL-HQVIVARFADDQLIIDFDNFVRCLVRLETL 672 + HQV+ ++ +DF+ FV + ++ + Sbjct: 155 DDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDV 189 Score = 43.1 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 44/102 (43%), Gaps = 18/102 (17%) Query: 605 QKYQKIYREIDVDRSGTMNSYEM----RKALEEAG--------FKMPCQLHQVIVARFAD 652 ++ +I+R++D + G ++ E+ RK ++ G ++ ++ ++ + D Sbjct: 40 KELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFD 99 Query: 653 DQLIIDFDNFVRCLV------RLETLFKIFKQLDPENTGTIE 688 I++ FV + E L F+Q D + +G I Sbjct: 100 RNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKIT 141 >5JN2-A nrPDB Length = 525 Score = 56.6 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 64/157 (40%), Gaps = 11/157 (7%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVL-AKRQDIKS-DGFSIE-TCKIM 580 ++ D +F ++ D ++ EL + ++ K QD D ++E + Sbjct: 369 LTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQV 428 Query: 581 VDMLDSDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 +D +D D +G + EF + ++ ++ +R D D SG ++S E+ + Sbjct: 429 LDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVS 488 Query: 635 GFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLET 671 V+ ++ +DFD F + L++L Sbjct: 489 DVD-SETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCG 524 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 27/129 (20%) Query: 573 SIETCKIMVDM---LDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 S + K + + +D +G G+L E I+ Y+++ R D S +++ Sbjct: 371 SQDETKELTAIFHKMDKNGDGQLDRAEL------IEGYKELMRMKGQDAS-MLDAS---- 419 Query: 630 ALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRC------LVRLETLFKIFKQLDPEN 683 + ++ QV+ A D I++ FV L+ E L + F+ D +N Sbjct: 420 -------AVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDN 472 Query: 684 TGTIELDLI 692 +G I + Sbjct: 473 SGKISSTEL 481 >3Q5I-A nrPDB Length = 504 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 57/151 (37%), Gaps = 12/151 (7%) Query: 529 DIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIET-CKIMVDMLDS 586 + +F +L D ++ EL VL ++ + ++E ++ +D Sbjct: 352 EERKELTDIFKKLDKNGDGQLDKKELIEGYN-VLRNFKNELGELKNVEEEVDNILKEVDF 410 Query: 587 DGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC 640 D +G + EF + ++ ++ + D D+SG + E+ + Sbjct: 411 DKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT--SISE 468 Query: 641 QLH-QVIVARFADDQLIIDFDNFVRCLVRLE 670 + V+ + +IDFD FV + ++ Sbjct: 469 KTWNDVLGEADQNKDNMIDFDEFVSMMHKIC 499 Score = 49.6 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 23/133 (17%), Positives = 51/133 (38%), Gaps = 21/133 (15%) Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEM--- 627 C + +M +GS KL + +K+ ++ I++++D + G ++ E+ Sbjct: 321 CGALSNMRKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEG 380 Query: 628 ----RKALEEAGF--KMPCQLHQVIVARFADDQLIIDFDNFVRCLV------RLETLFKI 675 R E G + ++ ++ D I++ F+ + E L + Sbjct: 381 YNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRA 440 Query: 676 FKQLDPENTGTIE 688 F D + +G I Sbjct: 441 FNLFDTDKSGKIT 453 >5OTJ-D nrPDB Length = 110 Score = 55.4 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 27/61 (44%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRC 665 ++I++ D + G ++ E+ AL G ++ +++ D IDF+ F+ Sbjct: 4 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISF 63 Query: 666 L 666 Sbjct: 64 C 64 Score = 37.3 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 10/67 (14%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D R+F + D +IS EL LR + + S + + M+ +D+DG G Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGST---------SADEVQRMMAEIDTDGDG 53 Query: 591 KLGLKEF 597 + EF Sbjct: 54 FIDFNEF 60 >5H7D-E nrPDB Length = 120 Score = 55.4 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFD 660 +IQ +++ + D D GT+ + E+ + G +L +I AD IDF Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 661 NFVRCLVR 668 F+ + R Sbjct: 113 EFLTMMAR 120 Score = 36.5 bits (83), Expect = 0.034, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 46/114 (40%), Gaps = 15/114 (13%) Query: 491 PNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGE-DAEIS 549 PN +G S +DD ++ + + + F+ F+ + D I+ Sbjct: 21 PNLNGRQVAAFIS------SLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTIT 74 Query: 550 AFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 EL T++R + Q+ + M++ +D+DG+G + EF + + Sbjct: 75 TKELGTVMRSL---GQNPTE-----AELQDMINEVDADGNGTIDFPEFLTMMAR 120 Score = 34.6 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 23/51 (45%), Gaps = 6/51 (11%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYE 626 + D DG G + KE + + + Q + E+D D +GT++ E Sbjct: 63 SLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 113 >3K21-A nrPDB Length = 191 Score = 55.4 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 ++K + + +D D G + +++K LE+ G K+P ++ +D ID+ F+ Sbjct: 51 VEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 664 RCLVRLETLFK-----IFKQLDPENTGTIELDLISWL 695 + + L K F+ D +N G I ++ + Sbjct: 111 AAALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHI 147 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 21/149 (14%) Query: 526 SEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 S D + + F L + I+ +L+ L + K ++ + +++D + Sbjct: 46 SNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLP------YNFD---LLLDQI 96 Query: 585 DSDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKALEEAGFKMP 639 DSDGSGK+ EF ++ K +R DVD G + + E+ L K Sbjct: 97 DSDGSGKIDYTEFIAAALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGN 156 Query: 640 ------CQLHQVIVARFADDQLIIDFDNF 662 ++ ++I ++ IDF F Sbjct: 157 ITQRDVNRVKRMIRDVDKNNDGKIDFHEF 185 Score = 42.3 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 9/97 (9%) Query: 506 KADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQ 565 K DY I A L+ +S+ I FR +F D EI+ EL IL K Sbjct: 103 KIDYTEF---IAAALDRKQLSKKLIYCAFR-VFD--VDNDGEITTAELAHILYNGNKKGN 156 Query: 566 DIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 + D + K M+ +D + GK+ EF + Sbjct: 157 ITQRD---VNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >5B8I-B nrPDB Length = 171 Score = 55.0 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 17/132 (12%) Query: 546 AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKE-------FY 598 ++ + TI R + S+ S M+ + D DG G + +E F Sbjct: 28 MKLDRDKSGTIERDEFLSLPQVSSNPLST----RMIAIFDEDGGGDVDFQEFVSGLSAFS 83 Query: 599 ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKMPC-QLHQV----IVARFAD 652 K +K + ++ D+DR G +++ E+ L+ G + QL Q+ I+ D Sbjct: 84 SKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLD 143 Query: 653 DQLIIDFDNFVR 664 I F+ F R Sbjct: 144 GDGRISFEEFTR 155 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 17/102 (16%) Query: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 652 +E LW + + ++D D+SGT+ E + + + + +I D Sbjct: 16 DHEEVDRLWKR-------FMKLDRDKSGTIERDEFLSLPQVSSNPLSTR---MIAIFDED 65 Query: 653 DQLIIDFDNFVRCLV-------RLETLFKIFKQLDPENTGTI 687 +DF FV L + E L FK D + G I Sbjct: 66 GGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFI 107 >4YZB-A nrPDB Length = 491 Score = 55.0 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 68/157 (43%), Gaps = 11/157 (7%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQ-TILRRVLAKRQDIKS-DGFSIE-TCKIM 580 ++ ++ ++F ++ D ++ EL + + K +D+ + D +IE + + Sbjct: 332 LTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQV 391 Query: 581 VDMLDSDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 +D +D D +G + EF + Q+ ++ + D D SG ++S E+ + Sbjct: 392 LDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFGVS 451 Query: 635 GFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLET 671 +V+ ++ +DF+ F + L++L Sbjct: 452 EVD-SETWRRVLAEVDRNNDGEVDFEEFRQMLLKLCG 487 Score = 43.1 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 77/199 (38%), Gaps = 30/199 (15%) Query: 519 NLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCK 578 +L ++ + D R++ A + ISA + L K D +D + + + Sbjct: 251 DLPQWKKVSEPAKDLIRKMLAYVP--TMRISARD---ALEHEWLKTTDAATDSIDVPSLE 305 Query: 579 I-MVDMLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKA- 630 ++++ G+ KL + +K+ + KI++ +D + G ++ E+ + Sbjct: 306 STILNIRQFQGTQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGY 365 Query: 631 ---LEEAGFKMPC--------QLHQVIVARFADDQLIIDFDNFVRC------LVRLETLF 673 ++ G + ++ QV+ A D I++ FV L+ + L Sbjct: 366 VELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLE 425 Query: 674 KIFKQLDPENTGTIELDLI 692 + F D + +G I + Sbjct: 426 RAFGMFDADGSGKISSSEL 444 >2LVK-A nrPDB Length = 77 Score = 54.6 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 27/61 (44%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRC 665 ++I++ D + G ++ E+ AL G ++ +++ D IDF+ F+ Sbjct: 3 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISF 62 Query: 666 L 666 Sbjct: 63 C 63 Score = 36.9 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 10/67 (14%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D R+F + D +IS EL LR + + S + + M+ +D+DG G Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGST---------SADEVQRMMAEIDTDGDG 52 Query: 591 KLGLKEF 597 + EF Sbjct: 53 FIDFNEF 59 >2M29-A nrPDB Length = 171 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 36/188 (19%), Positives = 68/188 (36%), Gaps = 50/188 (26%) Query: 495 GDFCIRVFSEKKADYQAVDDEIEANLEEFDISED------DIDDGFRRLFAQLAGEDAEI 548 G R+F + + +E++A EEFD +D ++ D R L + E+ Sbjct: 9 GPLLNRMFGKDRELGPEELEELQAAFEEFDTDQDGYIGYRELGDCMRTL--GYMPTEMEL 66 Query: 549 SAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL-------- 600 +++ ++ GF + +EF L Sbjct: 67 ----------LEVSQHVKMRMGGF-------------------VDFEEFVELISPKLREE 97 Query: 601 ---WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKMP-CQLHQVIVARFADDQL 655 +++ + +RE D DR G + E+R+A G + +L +++ + Sbjct: 98 TAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDG 157 Query: 656 IIDFDNFV 663 IDFD FV Sbjct: 158 TIDFDEFV 165 Score = 51.2 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 39/105 (37%), Gaps = 12/105 (11%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRC- 665 Q + E D D+ G + E+ + G+ +L +V +DF+ FV Sbjct: 31 QAAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELI 90 Query: 666 ----------LVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 ++ + L F++ D + G I + + ++L Sbjct: 91 SPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALL 135 Score = 31.5 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 20/57 (35%), Gaps = 7/57 (12%) Query: 544 EDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 D I+ EL+ + + M+ +D +G G + EF ++ Sbjct: 118 RDGRITVAELRQ-------AAPALLGEPLEGTELDEMLREMDLNGDGTIDFDEFVMM 167 >2BL0-C nrPDB Length = 142 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 62/158 (39%), Gaps = 29/158 (18%) Query: 513 DDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGF 572 DD++ E F++ + + I+ LQT+L++ ++ F Sbjct: 2 DDQVSEFKEAFELFDSE--------------RTGFITKEGLQTVLKQF---GVRVEPAAF 44 Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSY 625 + M + D+ G+GK+ EF + + K ++ +R D + +G + Sbjct: 45 N-----EMFNEADATGNGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKA 99 Query: 626 EMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFV 663 ++ AL G ++ + ++ I +DNF+ Sbjct: 100 ALQDALLNLGDRLKPHEFAEFLGITETEKGQIRYDNFI 137 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQ-VIVARFADDQLIIDFDNF 662 + ++++ + D +R+G + ++ L++ G ++ + A I F F Sbjct: 5 VSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFPEF 64 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTI 687 + + R + L + F+ DPE TG I Sbjct: 65 LSMMGRRMKQTTSEDILRQAFRTFDPEGTGYI 96 >1SR6-C nrPDB Length = 156 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 62/153 (40%), Gaps = 22/153 (14%) Query: 525 ISEDDIDD--GFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 582 +S+D+IDD LF G D + AF+L + R + ++ D F++ M Sbjct: 3 LSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRN--EDVFAVGGTHKM-- 58 Query: 583 MLDSDGSGKLGLKEFYILWTKIQK--------YQKIYREIDVDRSGTMNSYEMRKALEEA 634 G L +EF + + Y + ++ D + G ++ E+R L Sbjct: 59 -----GEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTAL 113 Query: 635 GFKMPCQLHQVIVARFA---DDQLIIDFDNFVR 664 G ++ + I+ D + + +++FV+ Sbjct: 114 GERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVK 146 Score = 30.0 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 33/95 (34%), Gaps = 10/95 (10%) Query: 603 KIQKYQKIYREID--VDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD 660 +I + ++ D R G ++++++ G + + + + F+ Sbjct: 7 EIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGEKSLPFE 66 Query: 661 NFV---RCLVRLETLF-----KIFKQLDPENTGTI 687 F+ L+ E + FK D E G I Sbjct: 67 EFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFI 101 >4ZCV-A nrPDB Length = 165 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 58/144 (40%), Gaps = 11/144 (7%) Query: 522 EFDISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIM 580 E + + + LF L D + ELQ LR + + + + Sbjct: 3 EDACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNL--------GIPLGQDAEEKI 54 Query: 581 VDMLDSDGSGKLGLKEF-YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP 639 D + GKL +EF L +K + ++ +D + G + + E+ ++L+ G + Sbjct: 55 FTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTIS 114 Query: 640 CQLHQVIVAR-FADDQLIIDFDNF 662 Q ++I+ D + +D++ + Sbjct: 115 EQQAELILQSIDVDGTMTVDWNEW 138 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVI-VARFADDQLIIDFDNFV 663 +Y+ +++ +D + G ++ E+++ L G + + I + +DF+ F+ Sbjct: 13 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFM 72 Query: 664 RCLV-RLETLFKIFKQLDPENTGTIELDLI 692 + L + + FK LD N G IE I Sbjct: 73 KYLKDHEKKMKLAFKSLDKNNDGKIEASEI 102 >2I08-A nrPDB Length = 78 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVRL 669 + + R+ Sbjct: 69 LTMMARI 75 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 10/84 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + + + M++ Sbjct: 4 LTEEQIAE-FKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTE--------AELQDMINE 54 Query: 584 LDSDGSGKLGLKEFYILWTKIQKY 607 +D+DG+G + EF + +I KY Sbjct: 55 VDADGNGTIDFPEFLTMMARIMKY 78 >2LHH-A nrPDB Length = 128 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 + + R + L + FK D G I + + S+ Sbjct: 69 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 112 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 22/131 (16%) Query: 518 ANLEEFDISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIET 576 +NL E I+E F+ FA ++ IS+ EL T++R + S Sbjct: 2 SNLTEEQIAE------FKEAFALFDKDNNGSISSSELATVMRSLGLSP--------SEAE 47 Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRK 629 +++ +D DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ Sbjct: 48 VNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKH 107 Query: 630 ALEEAGFKMPC 640 L G K+ Sbjct: 108 VLTSIGEKLTD 118 >5JOJ-A nrPDB Length = 97 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-----GFKMPCQLHQVIVARFADDQLII 657 ++ + ++ + ++D D +G ++ E+ + A G+++ ++ D I Sbjct: 10 EMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRI 69 Query: 658 DFDNFVRCLVRLET--LFKIFKQ 678 FD F++ L++ + K F++ Sbjct: 70 SFDEFIKIFHGLKSTDVAKTFRK 92 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 D+ R FA++ + IS EL + + + E + ++ D Sbjct: 8 DEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVR----EITENLMATGDL 63 Query: 587 DGSGKLGLKEFYILWTKIQ--KYQKIYRE 613 D G++ EF ++ ++ K +R+ Sbjct: 64 DQDGRISFDEFIKIFHGLKSTDVAKTFRK 92 >5COC-A nrPDB Length = 130 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 62 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 121 Query: 663 VRCLVR 668 + + R Sbjct: 122 LTMMAR 127 Score = 38.8 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 41/106 (38%), Gaps = 14/106 (13%) Query: 529 DIDDGFRRLFAQLAGEDAEISAFELQ--TILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 ++++ R F Q +D SA L L A ++ I K + D Sbjct: 21 NLNEEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEEC------IAEFKEAFSLFDK 74 Query: 587 DGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYE 626 DG G + KE + + + Q + E+D D +GT++ E Sbjct: 75 DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 120 Score = 37.7 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 520 LEEFDISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCK 578 L + + ++ F+ F+ + D I+ EL T++ R L + + + Sbjct: 51 LNDAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVM-RSLGQNP-------TEAELQ 102 Query: 579 IMVDMLDSDGSGKLGLKEFYILWTK 603 M++ +D+DG+G + EF + + Sbjct: 103 DMINEVDADGNGTIDFPEFLTMMAR 127 >4ORC-B nrPDB Length = 170 Score = 52.7 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 13/101 (12%) Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRK 629 + ++D+ D+DG+G++ KEF ++ QK + +R D+D+ G +++ E+ + Sbjct: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 Query: 630 ALEEA-GFKMPC-QLHQV----IVARFADDQLIIDFDNFVR 664 L+ G + QL Q+ I+ D I F+ F Sbjct: 115 VLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 40/92 (43%), Gaps = 10/92 (10%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNF 662 +I++ K ++++D+D SG+++ E E + + +VI D +DF F Sbjct: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 Query: 663 VRCLVRL-------ETLFKIFKQLDPENTGTI 687 + + + + L F+ D + G I Sbjct: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 Score = 37.7 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 45/138 (32%), Gaps = 18/138 (13%) Query: 572 FSIETCKIM---VDMLDSDGSGKLGLKEFYILWTKIQK--YQKIYREIDVDRSGTMNSYE 626 F + K + LD D SG L ++EF L Q Q++ D D +G ++ E Sbjct: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 Query: 627 MRKALEEAGFKMPCQLHQVIVAR--FADDQLIIDFDNFVRCLVRL-----------ETLF 673 + + + K + R D I + L + + + Sbjct: 75 FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD 134 Query: 674 KIFKQLDPENTGTIELDL 691 K D + G I + Sbjct: 135 KTIINADKDGDGRISFEE 152 >4N5X-A nrPDB Length = 199 Score = 52.7 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 57/139 (41%), Gaps = 11/139 (7%) Query: 527 EDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 + + + LF L D + ELQ LR + + + + D Sbjct: 17 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNL--------GIPLGQDAEEKIFTTGD 68 Query: 586 SDGSGKLGLKEF-YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQ 644 + GKL +EF L +K + ++ +D + G + + E+ ++L+ G + Q + Sbjct: 69 VNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAE 128 Query: 645 VIVAR-FADDQLIIDFDNF 662 +I+ D + +D++ + Sbjct: 129 LILQSIDVDGTMTVDWNEW 147 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVI-VARFADDQLIIDFDNFV 663 +Y+ +++ +D + G ++ E+++ L G + + I + +DF+ F+ Sbjct: 22 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFM 81 Query: 664 RCLV-RLETLFKIFKQLDPENTGTIELDLI 692 + L + + FK LD N G IE I Sbjct: 82 KYLKDHEKKMKLAFKSLDKNNDGKIEASEI 111 >2HF5-A nrPDB Length = 68 Score = 52.7 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 34/68 (50%), Gaps = 7/68 (10%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEM 627 + M++ +D+DG+G + EF + + ++ ++ +R D D +G +++ E+ Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 628 RKALEEAG 635 R + G Sbjct: 61 RHVMTNLG 68 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 7/59 (11%) Query: 641 QLHQVIVARFADDQLIIDFDNFVRCLVRL-------ETLFKIFKQLDPENTGTIELDLI 692 +L +I AD IDF F+ + R E + + F+ D + G I + Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 >2OPO-A nrPDB Length = 86 Score = 51.9 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 29/59 (49%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNF 662 I ++I++ D + G ++S E+ AL+ G P ++ +++ D I FD F Sbjct: 10 IADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFISFDEF 68 Score = 35.4 bits (80), Expect = 0.082, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 24/55 (43%), Gaps = 9/55 (16%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYI 599 D +IS+ EL L+ + + D + M+ +D+DG G + EF Sbjct: 25 DGKISSSELGDALKTLGSVTPD---------EVRRMMAEIDTDGDGFISFDEFTD 70 >2LV7-A nrPDB Length = 100 Score = 51.9 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDN 661 ++++ ++ ++ D D +G ++ E+ A+ G+ +VI+ R D +DF+ Sbjct: 34 ELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEE 93 Query: 662 FVRCL 666 FV L Sbjct: 94 FVTLL 98 Score = 31.1 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 10/79 (12%) Query: 523 FDISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMV 581 DI ED++++ R F + IS EL T +R + + ++++ Sbjct: 28 VDIPEDELEE-IREAFKVFDRDGNGFISKQELGTAMRSL--------GYMPNEVELEVII 78 Query: 582 DMLDSDGSGKLGLKEFYIL 600 LD DG G++ +EF L Sbjct: 79 QRLDMDGDGQVDFEEFVTL 97 >3E3R-A nrPDB Length = 204 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 7/94 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNF 662 IQ + +R++D D S ++++ E R+ L + G + + + + + +D + F Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEF 95 Query: 663 VRCL------VRLETLFKIFKQLDPENTGTIELD 690 +R L R + F +LD G + +D Sbjct: 96 LRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVD 129 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 47/132 (35%), Gaps = 18/132 (13%) Query: 532 DGFRRLFAQLAGEDAE-ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 G R F QL + + + A E + L ++ +++G C+ D +GSG Sbjct: 37 QGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEG----VCRK----WDRNGSG 88 Query: 591 KLGLKEFYILW------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF---KMPCQ 641 L L+EF + + ++D G + ++R + Sbjct: 89 TLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEW 148 Query: 642 LHQVIVARFADD 653 ++ RF D+ Sbjct: 149 TEDEVLRRFLDN 160 >4Q57-A nrPDB Length = 65 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 663 VRCL 666 + + Sbjct: 61 LTMM 64 Score = 35.4 bits (80), Expect = 0.088, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 6/59 (10%) Query: 574 IETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYE 626 I K + D DG G + KE + + + Q + E+D D +GT++ E Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 59 Score = 34.6 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 9/70 (12%) Query: 534 FRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592 F+ F+ + D I+ EL T++R + Q+ + M++ +D+DG+G + Sbjct: 4 FKEAFSLFDKDGDGTITTKELGTVMRSL---GQNPTE-----AELQDMINEVDADGNGTI 55 Query: 593 GLKEFYILWT 602 EF + Sbjct: 56 DFPEFLTMMA 65 >3LIJ-A nrPDB Length = 494 Score = 51.2 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 80/206 (38%), Gaps = 23/206 (11%) Query: 510 QAVDDEIEANLEEFDISE-DDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIK 568 Q + ++E FD E ++ +G + L Q+ D++ Q + + + K Sbjct: 243 QEILRKVEKGKYTFDSPEWKNVSEGAKDLIKQMLQFDSQRRISAQQALEHPWIKEMCSKK 302 Query: 569 SDGFSIETCKIMVDMLDS-DGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGT 621 G + + ++ + S KL + +K+ ++ I+R ID + G Sbjct: 303 ESGIELPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQ 362 Query: 622 MNSYEMRKAL-EEAGF--------KMPCQLHQVIVARFADDQLIIDFDNFVRC------L 666 ++ E+ + +G ++ ++ ++ A D ID+ FV L Sbjct: 363 LDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSL 422 Query: 667 VRLETLFKIFKQLDPENTGTIELDLI 692 + + L F++ D + G I +D + Sbjct: 423 LSKDKLESAFQKFDQDGNGKISVDEL 448 Score = 48.9 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 22/159 (13%), Positives = 61/159 (38%), Gaps = 18/159 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++ + +F + D ++ EL ++ + + F + + VD Sbjct: 339 LTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAV----FDLPQIESEVDA 394 Query: 584 L----DSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKALEE 633 + D D +G + EF + + K + +++ D D +G ++ E+ Sbjct: 395 ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL 454 Query: 634 AGFKMPCQL-HQVIVARFADDQLIIDFDNFVRCLVRLET 671 + + ++I +++ +DF+ F + + +L + Sbjct: 455 D--HLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCS 491 Score = 32.7 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 29/187 (15%), Positives = 75/187 (40%), Gaps = 34/187 (18%) Query: 434 YEVPEELSGQTNIHLSKNFFLTNRARERSDTF----------INLREVLNRFKLPPGEYI 483 ++ ++L+ ++++ +E +D F ++ +E+++ + GE + Sbjct: 321 FQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEV 380 Query: 484 LVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDI-SEDDIDDGFRRLFAQLA 542 V + + D + + Y + + ++ + S+D ++ F++ F Q Sbjct: 381 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQK-FDQ-- 437 Query: 543 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIE-----TCKIMVDMLDSDGSGKLGLKEF 597 + +IS EL ++ F ++ T K M+ +DS+ G + +EF Sbjct: 438 DGNGKISVDELASV---------------FGLDHLESKTWKEMISGIDSNNDGDVDFEEF 482 Query: 598 YILWTKI 604 + K+ Sbjct: 483 CKMIQKL 489 >3IFK-A nrPDB Length = 90 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LTMMAR 74 Score = 36.1 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 47/108 (43%), Gaps = 23/108 (21%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++E+ I + F+ F+ + D I+ EL T++R + + + M++ Sbjct: 4 LTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE--------AELQDMINE 54 Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 +D+DG+G + EF + + + D D + E+R+A Sbjct: 55 VDADGNGTIDFPEFLTMMAR--------KMKDTD-----SEEEIREAF 89 >5JOL-A nrPDB Length = 82 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 31/69 (44%), Gaps = 5/69 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-----GFKMPCQLHQVIVARFADDQLII 657 ++ + ++ + ++D D +G ++ E+ + A G+++ ++ D I Sbjct: 10 EMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRI 69 Query: 658 DFDNFVRCL 666 FD F++ Sbjct: 70 SFDEFIKIF 78 Score = 30.0 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 D+ R FA++ + IS EL + + + E + ++ D Sbjct: 8 DEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVR----EITENLMATGDL 63 Query: 587 DGSGKLGLKEFYILWTKIQ 605 D G++ EF ++ ++ Sbjct: 64 DQDGRISFDEFIKIFHGLK 82 >2JOJ-A nrPDB Length = 77 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 39/77 (50%), Gaps = 7/77 (9%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM-PCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D +++G+++ +E++ A+ GF + ++ +++ + I FD+F Sbjct: 7 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDF- 65 Query: 664 RCLVRLETLFKIFKQLD 680 L+ + + K D Sbjct: 66 -----LDIMTEKIKNRD 77 >2B1U-A nrPDB Length = 71 Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA-RFADDQLIIDFDNF 662 ++ Q +R D D G + E+R+A+ G +P + ++ D ++++ F Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 663 VRCL 666 R L Sbjct: 65 ARML 68 Score = 30.4 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 26/73 (35%), Gaps = 11/73 (15%) Query: 528 DDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSD 587 +D+ FR F Q D I+ EL+ + E M+ D D Sbjct: 6 EDLQVAFRA-FDQ--DGDGHITVDELRRAM--------AGLGQPLPQEELDAMIREADVD 54 Query: 588 GSGKLGLKEFYIL 600 G++ +EF + Sbjct: 55 QDGRVNYEEFARM 67 >2ROB-A nrPDB Length = 70 Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ ++ ++ D D++G +++ E+R + G K+ ++ Q+I D ++++ FV Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 63 Query: 664 RCLVRLE 670 + ++ + Sbjct: 64 KMMMTVR 70 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 +E+++ + F+ +F + ++ ISA EL+ ++ + K D E + M+ D Sbjct: 2 AEEELKEAFK-VFDK--DQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEAD 50 Query: 586 SDGSGKLGLKEFYILW 601 DG G++ +EF + Sbjct: 51 LDGDGQVNYEEFVKMM 66 >2RO8-A nrPDB Length = 79 Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D G + + E+ + G +L +I AD IDF F Sbjct: 9 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LNLMAR 74 Score = 35.0 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 9/77 (11%) Query: 528 DDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 D+ F+ F+ + D I+ EL T++R + Q+ + M++ +D+ Sbjct: 6 DEQISEFKEAFSLFDKDGDGCITTKELGTVMRSL---GQNPTE-----AELQDMINEVDA 57 Query: 587 DGSGKLGLKEFYILWTK 603 DG+G + EF L + Sbjct: 58 DGNGTIDFPEFLNLMAR 74 Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 6/59 (10%) Query: 574 IETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYE 626 I K + D DG G + KE + + + Q + E+D D +GT++ E Sbjct: 9 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 67 >2KN2-A nrPDB Length = 92 Score = 50.0 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ ++ ++ D D++G +++ E+R + G K+ ++ Q+I D ++++ FV Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 68 Query: 664 RCLVRLE 670 + ++ + Sbjct: 69 KMMMTVR 75 Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 +E+++ + F+ +F + ++ ISA EL+ ++ + K D E + M+ D Sbjct: 7 AEEELKEAFK-VFDK--DQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEAD 55 Query: 586 SDGSGKLGLKEFYILW 601 DG G++ +EF + Sbjct: 56 LDGDGQVNYEEFVKMM 71 >4WPX-A nrPDB Length = 177 Score = 50.0 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 70/177 (39%), Gaps = 31/177 (17%) Query: 506 KADYQAVDDEIEANLEE-FDISEDDID-----DGFRRLFAQLAGEDAEISAFELQTILRR 559 + DY + DE + + E F++ + + D + FR + L ++ + +L R Sbjct: 14 REDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRAL---GFDLPKQQTYDMLVR 70 Query: 560 VLAKRQDIKSDG--------FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIY 611 + + D F++ T + + L + + ++ + Sbjct: 71 HGQRPANWPHDQECPPVYRQFNLATAQALAGTLIRQRDPR-------------DELRRAF 117 Query: 612 REIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLV 667 R DVD G + ++RK ++ G +P + +I ++ + +D D F+R ++ Sbjct: 118 RLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDEFLRLMM 174 >5Z1Q-A nrPDB Length = 95 Score = 49.6 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM-PCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D +++G+++ +E++ A+ GF + ++ +++ + I FD+F+ Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFL 86 Query: 664 RCL 666 + Sbjct: 87 DIM 89 Score = 28.4 bits (62), Expect = 9.8, Method: Composition-based stats. Identities = 6/24 (25%), Positives = 15/24 (62%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTK 603 +++ D +G+G +G +F + T+ Sbjct: 68 LMNEYDREGNGYIGFDDFLDIMTE 91 >3MSE-B nrPDB Length = 180 Score = 49.6 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQL 655 E ++ I+ +++ ++D + +G+++ E+ L G K +++++ A +D+ Sbjct: 30 ELSVINNHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIK-KWDINRILQALDINDRG 88 Query: 656 IIDFDNFVRCLVRLET-----LFKIFKQLDPENTGTI 687 I + F+ R + L F ++D + G I Sbjct: 89 NITYTEFMAGCYRWKNIESTFLKAAFNKIDKDEDGYI 125 >2M5E-A nrPDB Length = 73 Score = 49.2 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ + ++ D D +G +++ E+R + G K+ ++ ++I D I+++ FV Sbjct: 8 EELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFV 67 Query: 664 RCLV 667 R +V Sbjct: 68 RMMV 71 Score = 32.3 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 526 SEDDIDDGFRRLFAQLAGEDAE--ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 SE+++ + F+ + D ISA EL+ ++ + K D + M+ Sbjct: 6 SEEELIEAFK-----VFDRDGNGLISAAELRHVMTNLGEKLTD--------DEVDEMIRE 52 Query: 584 LDSDGSGKLGLKEFYILW 601 D DG G + +EF + Sbjct: 53 ADIDGDGHINYEEFVRMM 70 Score = 29.2 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 6/50 (12%) Query: 583 MLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYE 626 + D DG+G + E + T + + ++ RE D+D G +N E Sbjct: 16 VFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEE 65 >2RO9-A nrPDB Length = 69 Score = 49.2 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ ++ +R D D++G +++ E+R + G K+ ++ ++I D I+++ FV Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 63 Query: 664 RCLV 667 + ++ Sbjct: 64 KVMM 67 Score = 35.4 bits (80), Expect = 0.095, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 11/76 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE+++ + FR +F + ++ ISA EL+ ++ + K D E M+ D Sbjct: 2 SEEELKEAFR-VFDK--DQNGFISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 50 Query: 586 SDGSGKLGLKEFYILW 601 DG G++ +EF + Sbjct: 51 VDGDGQINYEEFVKVM 66 >1FW4-A nrPDB Length = 71 Score = 48.9 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ ++ +R D D +G +++ E+R + G K+ ++ ++I D ++++ FV Sbjct: 6 EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 65 Query: 664 RCL 666 + + Sbjct: 66 QMM 68 Score = 35.8 bits (81), Expect = 0.072, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 4 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 52 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 53 IDGDGQVNYEEFVQMMT 69 Score = 31.9 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 6/60 (10%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 63 >2JNX-A nrPDB Length = 134 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 55/139 (39%), Gaps = 21/139 (15%) Query: 537 LFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLK 595 LF QL A D +S E++ V +KR + + +D DG+G++ L Sbjct: 5 LFKQLDANGDGSVSYEEVKAF---VSSKRPIKNEQLLQL-----IFKAIDIDGNGEIDLA 56 Query: 596 EFY---------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVI 646 EF L + + +Y+ +D D G + E+ ++ G+ ++ I Sbjct: 57 EFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY---EKVVDQI 113 Query: 647 VARFADDQLIIDFDNFVRC 665 + A+ I + F+ Sbjct: 114 MKADANGDGYITLEEFLAF 132 Score = 35.8 bits (81), Expect = 0.060, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 39/94 (41%), Gaps = 10/94 (10%) Query: 610 IYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNFV--RCL 666 +++++D + G+++ E++ + QL Q+I D ID F Sbjct: 5 LFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAA 64 Query: 667 VRLETLFK-------IFKQLDPENTGTIELDLIS 693 V+ + L ++K +D + G + + ++ Sbjct: 65 VKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVT 98 >1ZMZ-A nrPDB Length = 98 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 Q+ ++ + D D +GT++ E++ A+ GF+ ++ ++I + ++F +F+ Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFL 90 Query: 664 RCL 666 + Sbjct: 91 TVM 93 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 13/78 (16%) Query: 528 DDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSI--ETCKIMVDML 584 ++ R F + I EL+ +R + GF E K M+ + Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 76 Query: 585 DSDGSGKLGLKEFYILWT 602 D +G+GK+ +F + T Sbjct: 77 DKEGTGKMNFGDFLTVMT 94 Score = 32.3 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 30/58 (51%), Gaps = 6/58 (10%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 + + D+ D+DG+G + +KE + + ++ +K+ EID + +G MN + Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGD 88 >2N7L-C nrPDB Length = 141 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 13/95 (13%) Query: 511 AVDDEIEANLEEFDISEDDIDDGFRRLFA--QLAGEDAEISAFELQTILRRVLAKRQDIK 568 ++DD +A +E+ ++ + F+ F L ED IS EL ++ R+L + Sbjct: 15 SMDDIYKAAVEQLT---EEQKNEFKAAFDIFVLGAEDGSISTKELGKVM-RMLGQNP--- 67 Query: 569 SDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 + E + M+D +D DGSG + EF ++ + Sbjct: 68 ----TPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 98 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFVRCLVR 668 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 48 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 98 >6MI5-X nrPDB Length = 117 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 22/125 (17%) Query: 576 TCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 T K+ + D D G + LKE + + ++D D+ GT+++ E++ + EA Sbjct: 4 TTKVDIAAFDPDKDGTIDLKE------ALAAGSAAFDKLDPDKDGTLDAKELKGRVSEAD 57 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWL 695 K D+ +D + L + FK +P+N GTI+ ++ Sbjct: 58 LK----------KLDPDNDGTLDKKEY------LAAVEAQFKAANPDNDGTIDARELASP 101 Query: 696 CFSVL 700 S L Sbjct: 102 AGSAL 106 Score = 31.9 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 34/91 (37%), Gaps = 26/91 (28%) Query: 538 FAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKE 596 F +L + D + A EL+ + K+ LD D G L KE Sbjct: 33 FDKLDPDKDGTLDAKELKGRVSEADLKK-------------------LDPDNDGTLDKKE 73 Query: 597 FYILWTKIQKYQKIYREIDVDRSGTMNSYEM 627 + + + ++ + D GT+++ E+ Sbjct: 74 Y------LAAVEAQFKAANPDNDGTIDAREL 98 >1QX2-A nrPDB Length = 76 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 41/79 (51%), Gaps = 7/79 (8%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 S ++I F +FA G+ +IS EL+ +++ + + +++ M++ +D Sbjct: 3 SPEEIKGAFE-VFAAKEGDPNQISKEELKLVMQTL---GPSLLKGMSTLDE---MIEEVD 55 Query: 586 SDGSGKLGLKEFYILWTKI 604 +G G++ +EF ++ KI Sbjct: 56 KNGDGEVSFEEFLVMMKKI 74 >1JFJ-A nrPDB Length = 134 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 41/93 (44%), Gaps = 12/93 (12%) Query: 584 LDSDGSGKLGLKEFYILWTKIQ---------KYQKIYREIDVDRSGTMNSYEMRKALEEA 634 +D+DG+G++ EF + IQ + +Y+ +DVD G + E+ ++ Sbjct: 45 IDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKH 104 Query: 635 GFKMPCQLHQVIVARFADDQLIIDFDNFVRCLV 667 G ++ + ++ A+ I + F+ + Sbjct: 105 GI---EKVAEQVMKADANGDGYITLEEFLEFSL 134 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 48/134 (35%), Gaps = 14/134 (10%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRKAL 631 + + +D +G G + +E +K + + I++ ID D +G ++ E K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 632 EEA-GFKMPCQ---LHQVIVARFADDQLIIDFDNFVRCLVR--LETLFKIFKQLDPENTG 685 G + L + D + + + +E + + + D G Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDG 122 Query: 686 TIELDLISWLCFSV 699 I L +L FS+ Sbjct: 123 YITL--EEFLEFSL 134 >2KSZ-A nrPDB Length = 76 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNF 662 I +++ + D D G + E+ + +L +I AD I+FD F Sbjct: 9 IVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEF 68 Query: 663 VRCLVR 668 + + + Sbjct: 69 LSLMAK 74 Score = 38.8 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I D F+ F + D I+ EL T++R + + E + M+ Sbjct: 4 LSEEQIVD-FKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISE 54 Query: 584 LDSDGSGKLGLKEFYILWTK 603 +D+DG+G + EF L K Sbjct: 55 VDADGNGTIEFDEFLSLMAK 74 Score = 31.5 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 6/50 (12%) Query: 583 MLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 + D DG G + ++E + + ++ Q + E+D D +GT+ E Sbjct: 18 LFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDE 67 >5VLN-A nrPDB Length = 120 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 13/94 (13%) Query: 512 VDDEIEANLEEFDISEDDIDDGFRRLFA--QLAGEDAEISAFELQTILRRVLAKRQDIKS 569 +DD +A +E+ ++ + F+ F L ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLT---EEQKNEFKAAFDIFVLGAEDGSISTKELGKVM-RMLGQNP---- 52 Query: 570 DGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 + E + M+D +D DGSG + EF ++ + Sbjct: 53 ---TPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFVRCLVR 668 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >3L19-A nrPDB Length = 214 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 22/159 (13%), Positives = 61/159 (38%), Gaps = 18/159 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 ++ + +F + D ++ EL ++ + + F + + VD Sbjct: 56 LTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAV----FDLPQIESEVDA 111 Query: 584 L----DSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKALEE 633 + D D +G + EF + + K + +++ D D +G ++ E+ Sbjct: 112 ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL 171 Query: 634 AGFKMPCQL-HQVIVARFADDQLIIDFDNFVRCLVRLET 671 + + ++I +++ +DF+ F + + +L + Sbjct: 172 D--HLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCS 208 Score = 45.4 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 43/103 (41%), Gaps = 15/103 (14%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKAL-EEAGF--------KMPCQLHQVIVARFADDQL 655 ++ I+R ID + G ++ E+ + +G ++ ++ ++ A D Sbjct: 63 KELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNG 122 Query: 656 IIDFDNFVRC------LVRLETLFKIFKQLDPENTGTIELDLI 692 ID+ FV L+ + L F++ D + G I +D + Sbjct: 123 YIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDEL 165 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYIL----WTKIQKYQKIYREIDVDRSGTMNSYEMR 628 S + + D DG+GK+ + E + + + ++++ ID + G ++ E Sbjct: 141 SKDKLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNNDGDVDFEEFC 200 Query: 629 KALEEAGFKMPCQL 642 K +++ QL Sbjct: 201 KMIQKLCSNNEPQL 214 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 28/182 (15%), Positives = 74/182 (40%), Gaps = 24/182 (13%) Query: 434 YEVPEELSGQTNIHLSKNFFLTNRARERSDTF----------INLREVLNRFKLPPGEYI 483 ++ ++L+ ++++ +E +D F ++ +E+++ + GE + Sbjct: 38 FQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEV 97 Query: 484 LVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDI-SEDDIDDGFRRLFAQLA 542 V + + D + + Y + + ++ + S+D ++ F++ F Q Sbjct: 98 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQK-FDQ-- 154 Query: 543 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 + +IS EL ++ + + T K M+ +DS+ G + +EF + Sbjct: 155 DGNGKISVDELASVFGLDHLESK----------TWKEMISGIDSNNDGDVDFEEFCKMIQ 204 Query: 603 KI 604 K+ Sbjct: 205 KL 206 >1W7I-B nrPDB Length = 151 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 38/89 (42%), Gaps = 9/89 (10%) Query: 585 DSDGSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 D S ++ + F + + + Y + +R D + +G + E+R L G Sbjct: 58 DELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLG 117 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVR 664 KM + + ++A D I+++ F++ Sbjct: 118 EKMTEEEVETVLAGHEDSNGCINYEAFLK 146 Score = 33.8 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 40/104 (38%), Gaps = 14/104 (13%) Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADD- 653 EF +++++++ + D G + + + G ++ +V+ +D+ Sbjct: 3 EFNK--DQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEL 60 Query: 654 -QLIIDFDNFVRCLVRL---------ETLFKIFKQLDPENTGTI 687 +DF+ F+ L + E + F+ D E G + Sbjct: 61 KSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKV 104 >1H4B-A nrPDB Length = 84 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 27/55 (49%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNF 662 ++I++ D + G +++ E+ +AL+ G P ++ ++ D I F F Sbjct: 12 ERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEIDTDGDGFISFQEF 66 Score = 36.5 bits (83), Expect = 0.037, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 10/65 (15%) Query: 536 RLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGL 594 R+F + A D +ISA EL L+ + + + K M+ +D+DG G + Sbjct: 13 RIFKRFDANGDGKISAAELGEALKTL---------GSITPDEVKHMMAEIDTDGDGFISF 63 Query: 595 KEFYI 599 +EF Sbjct: 64 QEFTD 68 >1GGW-A nrPDB Length = 140 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 39/93 (41%), Gaps = 9/93 (9%) Query: 581 VDMLDSDGSGKLGLKEFYILWTKIQKYQ---------KIYREIDVDRSGTMNSYEMRKAL 631 + ++S ++ +++F + + + K ++ D D +G + E+R L Sbjct: 43 ITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVL 102 Query: 632 EEAGFKMPCQLHQVIVARFADDQLIIDFDNFVR 664 G K+ + ++ ++++ +FV+ Sbjct: 103 TSLGEKLSNEEMDELLKGVPVKDGMVNYHDFVQ 135 Score = 32.3 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 36/102 (35%), Gaps = 12/102 (11%) Query: 607 YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 Y++ + D +G + + L G I + +D + F++ L Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACG---QNPTLAEITEIESTLPAEVDMEQFLQVL 63 Query: 667 VR---------LETLFKIFKQLDPENTGTIELDLISWLCFSV 699 R E K F+ D + TG I + + ++ S+ Sbjct: 64 NRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSL 105 >3JAX-C nrPDB Length = 151 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 585 DSDGSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 D L ++F + I + Y + R D + +GT+ E+R L G Sbjct: 58 DEMNLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLG 117 Query: 636 FKMPCQLHQVIVARFADDQLIIDFDNFVR 664 KM + + +VA D I+++ VR Sbjct: 118 EKMTEEEVEQLVAGHEDSNGCINYEELVR 146 >2KZ2-A nrPDB Length = 94 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFV 663 ++ ++ +R D D +G +++ E+R + G K+ ++ ++I D ++++ FV Sbjct: 29 EEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 88 Query: 664 RCL 666 + + Sbjct: 89 QMM 91 Score = 35.4 bits (80), Expect = 0.080, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE++I + FR + + ISA EL+ ++ + K D E M+ D Sbjct: 27 SEEEIREAFR---VEDKDGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 75 Query: 586 SDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 76 IDGDGQVNYEEFVQMMT 92 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 6/68 (8%) Query: 565 QDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDR 618 Q + D S E + + D DG+G + E + T + ++ ++ RE D+D Sbjct: 19 QSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDG 78 Query: 619 SGTMNSYE 626 G +N E Sbjct: 79 DGQVNYEE 86 >5H53-B nrPDB Length = 146 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 47/105 (44%), Gaps = 11/105 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKMPCQLHQVIVARFADDQLIIDFD 660 T+IQ++++ + ID +R G ++ ++R G + + ++ + I+F Sbjct: 2 TQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMK---EASGPINFT 58 Query: 661 NFVRCL-VRL------ETLFKIFKQLDPENTGTIELDLISWLCFS 698 F+ +L + + FK LDPE GTI+ + L + Sbjct: 59 VFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLIT 103 >2GGZ-A nrPDB Length = 211 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 52/143 (36%), Gaps = 30/143 (20%) Query: 553 LQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QK 606 LQ L + K D + F D++ G + EF I QK Sbjct: 48 LQG-LNQKANKHIDQVYNTF------------DTNKDGFVDFLEFIAAVNLIMQEKMEQK 94 Query: 607 YQKIYREIDVDRSGTMNSYEMR------KALEEAGFKMPCQLHQVIVAR-FADDQLIIDF 659 + ++ D D +G+++ E+ +AL P + ++ + ++ + Sbjct: 95 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 154 Query: 660 DNFVRCLVR----LETLFKIFKQ 678 + F+ + + LE ++K F Sbjct: 155 EEFINGMAKDQDLLEIVYKSFDF 177 Score = 32.7 bits (73), Expect = 0.62, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 32/82 (39%), Gaps = 8/82 (9%) Query: 619 SGTMNSYEMRKALEEAGF--KMPCQLHQVIVARFADDQLIIDFDNFVRC--LVRLETLFK 674 SG +E + L G K + QV + +DF F+ L+ E + + Sbjct: 34 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 93 Query: 675 ----IFKQLDPENTGTIELDLI 692 FK D + G+I+ + + Sbjct: 94 KLKWYFKLYDADGNGSIDKNEL 115 >5H53-C nrPDB Length = 153 Score = 45.4 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 68/154 (44%), Gaps = 18/154 (11%) Query: 528 DDIDDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 + D F+ F D++I+ ++ +LR + ++ + E K++ + + Sbjct: 7 KEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRA-------LGTNPTNAEVKKVLGNPSNE 59 Query: 587 DGSGK-LGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + + K + ++F + I + + + R D + +GT+ E+R L G Sbjct: 60 EMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 119 Query: 637 KMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLE 670 KM + + ++A D I+++ FV+ ++ ++ Sbjct: 120 KMKEEEVEALMAGQEDSNGCINYEAFVKHIMSID 153 >4GJF-A nrPDB Length = 89 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Query: 512 VDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 +DD +A +E+ + + +F Q A ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVQGA-EDGCISTKELGKVM-RMLGQNP------ 52 Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 603 + E + M+D +D DGSG + EF ++ + Sbjct: 53 -TPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFVRCLVR 668 G +++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >2K7C-A nrPDB Length = 72 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKAL-EEAGFKM-PCQLHQVIVARFADDQLIIDFDN 661 +++ + +RE D + G +++ E+R+A+ + G ++ + ++I + +DF+ Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 662 FVRCLVR 668 FVR + R Sbjct: 66 FVRMMSR 72 Score = 35.0 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 35/76 (46%), Gaps = 10/76 (13%) Query: 528 DDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSD 587 ++ D FR D EIS EL+ +R++L Q D + ++ +D + Sbjct: 7 KELRDAFREFDTN---GDGEISTSELREAMRKLLG-HQVGHRD------IEEIIRDVDLN 56 Query: 588 GSGKLGLKEFYILWTK 603 G G++ +EF + ++ Sbjct: 57 GDGRVDFEEFVRMMSR 72 >5MWC-D nrPDB Length = 311 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIV-ARFADDQLIIDFDNFV 663 ++ + +R D D G ++ E + G ++ + I D IDFD F+ Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 664 R 664 + Sbjct: 211 K 211 Score = 33.8 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 8/64 (12%) Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAGF 636 D DG G + +EF + ++ Q +I+ + D D++G ++ E K +E Sbjct: 160 FDKDGDGFIDREEFGGI-IRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENVQL 218 Query: 637 KMPC 640 M Sbjct: 219 SMAD 222 Score = 31.5 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 513 DDEIEAN-LEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 D + AN L SE+++ + FR D I E I+R + + Sbjct: 135 DGPVMANSLTAMVPSEEELSECFRTFDKD---GDGFIDREEFGGIIR--------LTGEQ 183 Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ 605 + E + D+D +G++ EF + +Q Sbjct: 184 LTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENVQ 217 >1O1A-B nrPDB Length = 145 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 45/102 (44%), Gaps = 11/102 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKMPCQLHQVIVARFADDQLIIDFD 660 T+I+ +++ + ID + G ++ ++R+ G + + ++ + I+F Sbjct: 4 TEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIK---EASGPINFT 60 Query: 661 NFVRCL-VRL------ETLFKIFKQLDPENTGTIELDLISWL 695 F+ +L + + FK LDP+ G+I+ + L Sbjct: 61 VFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEEL 102 Score = 33.5 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 54/145 (37%), Gaps = 21/145 (14%) Query: 526 SEDDIDDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 E +I+D F+ F + D I +L+ R ++K+ E M+ Sbjct: 2 DETEIED-FKEAFTVIDQNADGIIDKDDLRE--TFAAMGRLNVKN-----EELDAMI--- 50 Query: 585 DSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 + SG + F ++ + K ++ +D D G++ + + L G + Sbjct: 51 -KEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGR 109 Query: 638 M-PCQLHQVIVARFADDQLIIDFDN 661 P ++ + A D +D+ N Sbjct: 110 FTPEEIKNMWAAFPPDVAGNVDYKN 134 >2K7B-A nrPDB Length = 76 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDN 661 +I++ ++ +RE D D+ G +N ++ + G+ +L ++ + +DFD+ Sbjct: 8 EIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDD 67 Query: 662 FVRCL 666 FV + Sbjct: 68 FVELM 72 >1I84-U nrPDB Length = 166 Score = 44.6 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 45/102 (44%), Gaps = 11/102 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKMPCQLHQVIVARFADDQLIIDFD 660 T+I+ +++ + ID + G ++ ++R+ G + + ++ + I+F Sbjct: 22 TEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIK---EASGPINFT 78 Query: 661 NFVRCL-VRL------ETLFKIFKQLDPENTGTIELDLISWL 695 F+ +L + + FK LDP+ G+I+ + L Sbjct: 79 VFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEEL 120 Score = 33.1 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 54/145 (37%), Gaps = 21/145 (14%) Query: 526 SEDDIDDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 E +I+D F+ F + D I +L+ R ++K+ E M+ Sbjct: 20 DETEIED-FKEAFTVIDQNADGIIDKDDLRE--TFAAMGRLNVKN-----EELDAMI--- 68 Query: 585 DSDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 + SG + F ++ + K ++ +D D G++ + + L G + Sbjct: 69 -KEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGR 127 Query: 638 M-PCQLHQVIVARFADDQLIIDFDN 661 P ++ + A D +D+ N Sbjct: 128 FTPEEIKNMWAAFPPDVAGNVDYKN 152 >2G9B-A nrPDB Length = 263 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 14/109 (12%) Query: 548 ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW----TK 603 I EL+ L+ +L K D E +M+ + DS+ GKL L E L Sbjct: 120 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 179 Query: 604 IQKYQKI----------YREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 + K+Q I + D D +G ++ E+ L++ K +L Sbjct: 180 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQEL 228 Score = 42.3 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 67/189 (35%), Gaps = 42/189 (22%) Query: 546 AEISAFELQTILRRVLAKRQDIKSDGFSIE-TCKIMVDMLDSDGSGKLGLKEFYILW--- 601 + ELQ +++ +L R K G + K VD GK+G+ E + Sbjct: 31 GYLEGKELQNLIQELLQAR---KKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTE 87 Query: 602 ------------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR 649 +++ K +R+ D D SG + + E++ L++ K + +A Sbjct: 88 ENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE 147 Query: 650 FAD---------DQLIIDFDNFVRCL------------VRLET--LFKIFKQLDPENTGT 686 + D + ++ R L +++ K F+ D + G Sbjct: 148 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 207 Query: 687 IELDLISWL 695 I+ + + L Sbjct: 208 IDENELDAL 216 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 22/107 (20%) Query: 609 KIYREIDVDRSGTMNSYEMR-------KALEEAGFKMPCQLHQVIVARFADDQLIID--- 658 +I+ D D SG + E++ +A ++AG ++ ++ + D I Sbjct: 20 EIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 79 Query: 659 -------FDNFV---RC--LVRLETLFKIFKQLDPENTGTIELDLIS 693 +NF+ RC L E K +++ D +++G IE + + Sbjct: 80 LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 126 >1TRF-A nrPDB Length = 76 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNF 662 I +++ + D D G +++ E+ + G + I+ D IDF+ F Sbjct: 8 IAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEF 67 Query: 663 VRCLVR 668 + +VR Sbjct: 68 LVMMVR 73 Score = 36.9 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 10/80 (12%) Query: 525 ISEDDIDDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I + F+ F + +IS EL T++ R+L + + E +++ Sbjct: 3 LSEEMIAE-FKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEE 53 Query: 584 LDSDGSGKLGLKEFYILWTK 603 +D DGSG + +EF ++ + Sbjct: 54 VDEDGSGTIDFEEFLVMMVR 73 >2ZFD-A nrPDB Length = 226 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 75/179 (41%), Gaps = 27/179 (15%) Query: 513 DDEIEANLEEFDISE-DDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 D E+ A F +SE + + + F+++ + + +D I+ E Q L + K++ + +D Sbjct: 32 DPELLARDTVFSVSEIEALYELFKKISSAVI-DDGLINKEEFQLALFKT-NKKESLFAD- 88 Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNS 624 + D+ D+ +G LG +EF + K ++ D+ + G + Sbjct: 89 -------RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 Query: 625 YEMRK----ALEEAGFKMPCQLHQVIV-----ARFADDQLIIDFDNFVRCLVRLETLFK 674 E+++ L E+G + + + I+ ID + + ++R +L K Sbjct: 142 QEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 >1TNP-A nrPDB Length = 90 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 6/88 (6%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQ 641 M D + L E I +++ + D D G +++ E+ + G + Sbjct: 2 SMTDQQAEARAFLSE-----EMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKE 56 Query: 642 LHQVIVAR-FADDQLIIDFDNFVRCLVR 668 I+ D IDF+ F+ +VR Sbjct: 57 ELDAIIEEVDEDGSGTIDFEEFLVMMVR 84 Score = 36.5 bits (83), Expect = 0.042, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 10/80 (12%) Query: 525 ISEDDIDDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE+ I + F+ F + +IS EL T++ R+L + + E +++ Sbjct: 14 LSEEMIAE-FKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEE 64 Query: 584 LDSDGSGKLGLKEFYILWTK 603 +D DGSG + +EF ++ + Sbjct: 65 VDEDGSGTIDFEEFLVMMVR 84 >5T7C-A nrPDB Length = 193 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 44/129 (34%), Gaps = 26/129 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPC 640 +G L + EF ++ Y + ++R D + GT++ E AL K+ Sbjct: 40 TGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQ 99 Query: 641 QLHQVIVARFADDQLIIDFDNFVRCLVRLETLF------------------KIFKQLDPE 682 +L D I + + + + KIF+Q+D Sbjct: 100 KLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTN 159 Query: 683 NTGTIELDL 691 N G + L+ Sbjct: 160 NDGKLSLEE 168 Score = 29.6 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 25/70 (35%), Gaps = 18/70 (25%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKY------------------QKIYREIDVDRSGTMN 623 M D DG+G + E + I K KI+R++D + G ++ Sbjct: 106 SMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLS 165 Query: 624 SYEMRKALEE 633 E + + Sbjct: 166 LEEFIRGAKS 175 >3I5I-C nrPDB Length = 159 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 60/169 (35%), Gaps = 37/169 (21%) Query: 510 QAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAF---ELQTILRRVLAKRQD 566 Q DEIE E FD LF G D ++ A +L L + Q Sbjct: 2 QLTKDEIEEVREVFD------------LFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQV 49 Query: 567 IKSDG--------FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDR 618 + G + +E + + + S +G EF + ++ D + Sbjct: 50 HQHGGTKKMGEKAYKLEEILPIYEEMSSKDTGTAA-DEF----------MEAFKTFDREG 98 Query: 619 SGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADD--QLIIDFDNFVR 664 G ++S E+R L+ G ++ Q + + + I +++ ++ Sbjct: 99 QGLISSAEIRNVLKMLGERITEDQCNDIFTFCDIREDIDGNIKYEDLMK 147 >2BL0-B nrPDB Length = 145 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 38/100 (38%), Gaps = 6/100 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID-FDNFVR 664 + Q+ ++ D D G ++ E+ AL G I + + + F R Sbjct: 6 QIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKTVYR 65 Query: 665 CLVRL-----ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 ++ + + F+ LD E GTI+ + L ++ Sbjct: 66 KPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNL 105 Score = 42.3 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 58/141 (41%), Gaps = 26/141 (18%) Query: 549 SAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGS--------GKLGLKEF--- 597 SA ++Q ++ K D K SIE + L + + G+L KEF Sbjct: 3 SADQIQECF-QIFDKDNDGKV---SIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLA 58 Query: 598 --YILWTK--------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM-PCQLHQVI 646 ++ K ++ +R +D + +GT+ E+R+ L G + ++ +++ Sbjct: 59 TFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEELM 118 Query: 647 VARFADDQLIIDFDNFVRCLV 667 I++++FV LV Sbjct: 119 KEVSVSGDGAINYESFVDMLV 139 >3TZ1-A nrPDB Length = 74 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFV 663 ++ ++ +R +D ++ G + +R L+ G ++ ++ +I D +D++ F Sbjct: 7 RELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFK 66 Query: 664 RCLVRLET 671 ++ + Sbjct: 67 CLMMSSDA 74 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 11/78 (14%) Query: 524 DISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 D+ E ++ + FR L + + I L+ IL+ + D + + + M+ Sbjct: 3 DLDERELKEAFRVLDKE---KKGVIKVDVLRWILKSL--------GDELTEDEIENMIAE 51 Query: 584 LDSDGSGKLGLKEFYILW 601 D+DGSG + +EF L Sbjct: 52 TDTDGSGTVDYEEFKCLM 69 Score = 28.8 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 16/26 (61%) Query: 670 ETLFKIFKQLDPENTGTIELDLISWL 695 L + F+ LD E G I++D++ W+ Sbjct: 7 RELKEAFRVLDKEKKGVIKVDVLRWI 32 >1F55-A nrPDB Length = 77 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LALMSR 74 Score = 31.5 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 15/87 (17%) Query: 518 ANLEEFDISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIET 576 +NL E I+E F+ FA ++ IS+ EL T++R + S Sbjct: 2 SNLTEEQIAE------FKEAFALFDKDNNGSISSSELATVMRSLGLSP--------SEAE 47 Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTK 603 +++ +D DG+ ++ EF L ++ Sbjct: 48 VNDLMNEIDVDGNHQIEFSEFLALMSR 74 >1UHN-A nrPDB Length = 189 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 75/179 (41%), Gaps = 27/179 (15%) Query: 513 DDEIEANLEEFDISE-DDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 D E+ A F +SE + + + F+++ + + +D I+ E Q L + K++ + +D Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVI-DDGLINKEEFQLALFKT-NKKESLFAD- 57 Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNS 624 + D+ D+ +G LG +EF + K ++ D+ + G + Sbjct: 58 -------RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 110 Query: 625 YEMRK----ALEEAGFKMPCQLHQVIV-----ARFADDQLIIDFDNFVRCLVRLETLFK 674 E+++ L E+G + + + I+ ID + + ++R +L K Sbjct: 111 QEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 169 >3JBH-C nrPDB Length = 156 Score = 43.1 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 62/139 (44%), Gaps = 31/139 (22%) Query: 545 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML------DSDGSGKLGLKEFY 598 + +I A +L +LR S++ CK + M+ D G KL L+EF Sbjct: 24 EGKIDARDLGDLLR--------------SLD-CKPTLAMVKKNGGSDKRGEKKLTLEEFL 68 Query: 599 ILWTKIQKYQKI---------YREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVA 648 ++++I+K +++ + D +GTM + E+ L G ++ + +++ Sbjct: 69 PIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIECEEIMRV 128 Query: 649 RFADDQLIIDFDNFVRCLV 667 DD + ++ FV+ ++ Sbjct: 129 CDEDDDGFLKYEPFVKTII 147 >5TBY-E nrPDB Length = 166 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 48/104 (46%), Gaps = 15/104 (14%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM---PCQLHQVIVARFADDQLIID 658 T+IQ++++ + +D +R G ++ ++R G ++ ++ ++I I+ Sbjct: 24 TQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALG-RVNVKNEEIDEMIKEA----PGPIN 78 Query: 659 FDNFVRCL-VRL------ETLFKIFKQLDPENTGTIELDLISWL 695 F F+ +L ET+ FK DPE G ++ D + + Sbjct: 79 FTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREM 122 >2JNF-A nrPDB Length = 158 Score = 42.3 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 43/104 (41%), Gaps = 13/104 (12%) Query: 602 TKIQKYQKIYREIDV-DRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDF 659 +++ + +R+ + + SG +++ ++ LE G + + Q+I IDF Sbjct: 10 NQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFGNGDIDF 69 Query: 660 DNFVRCLVRL-----------ETLFKIFKQLDPENTGTIELDLI 692 D+F R + L + F+ D E G I D++ Sbjct: 70 DSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVM 113 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 22/114 (19%) Query: 508 DYQAVDDEIEANLEEFD-ISEDDID-DGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQ 565 Q I ++EFD DID D F+ + A+ GE E++ ++Q L R + Sbjct: 44 GIQQTKSTIRQLIDEFDPFGNGDIDFDSFKIIGARFLGE--EVNPEQMQQEL-REAFRLY 100 Query: 566 DIKSDGF-----------------SIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 D + +G+ S E M+D +D+DGSG + +EF + T Sbjct: 101 DKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >5M6C-E nrPDB Length = 193 Score = 42.3 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 45/129 (34%), Gaps = 26/129 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPC 640 +G L + EF ++ Y + ++R D + GT++ E AL ++ Sbjct: 40 TGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQ 99 Query: 641 QLHQVIVARFADDQLIIDFDNFVRCLVRLETLF------------------KIFKQLDPE 682 +L D I + + + + + KIF+Q+D Sbjct: 100 KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 683 NTGTIELDL 691 N G + L+ Sbjct: 160 NDGKLSLEE 168 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 18/70 (25%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKY------------------QKIYREIDVDRSGTMN 623 M D DG+G + +E + I K +KI+R++D + G ++ Sbjct: 106 SMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLS 165 Query: 624 SYEMRKALEE 633 E + + Sbjct: 166 LEEFIRGAKS 175 >4D1E-A nrPDB Length = 876 Score = 42.3 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 + +++ + D ++G M+ + R L G+ + + +++ + Q + F +F Sbjct: 737 MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSF 796 Query: 663 VRCLVRLETLFKI 675 + + R Sbjct: 797 IDFMTRETADTDT 809 >3I5H-B nrPDB Length = 153 Score = 42.3 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 30/94 (31%), Gaps = 4/94 (4%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID----F 659 +Q+ ++ + ID DR G + +++ G P ++ F Sbjct: 15 MQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQLNFTAFLTLF 74 Query: 660 DNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 V + L F D + G I D + Sbjct: 75 GEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLK 108 Score = 36.1 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 42/123 (34%), Gaps = 22/123 (17%) Query: 539 AQLAGEDAEISAFELQTILRRVLAKRQDIKSDGF-SIETCKIM------------VDMLD 585 A+ A ++S ++Q + + D DGF +E K M ++ + Sbjct: 1 AEEAPRRVKLSQRQMQEL--KEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAML 58 Query: 586 SDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 + G+L F L+ + + + D D G + ++ LE G Sbjct: 59 KECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNF 118 Query: 639 PCQ 641 + Sbjct: 119 SKE 121 >2M8U-A nrPDB Length = 77 Score = 41.9 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 + ++ D D +G + +RK L E G MP ++ ++I + + ++ FV L Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFVGML 73 >1JC2-A nrPDB Length = 76 Score = 41.9 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 28/63 (44%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-MPCQLHQVIVARFADDQLIIDFDNFV 663 ++ +R D + G ++ E+ + L G + + ++ ++ IDFD F+ Sbjct: 10 EELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFL 69 Query: 664 RCL 666 + + Sbjct: 70 KMM 72 Score = 31.5 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 11/85 (12%) Query: 521 EEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIM 580 + SE+++ + FR +F + A D I EL ILR A + + E + + Sbjct: 3 DAKGKSEEELANCFR-IFDKNA--DGFIDIEELGEILR---ATGEHVIE-----EDIEDL 51 Query: 581 VDMLDSDGSGKLGLKEFYILWTKIQ 605 + D + G++ EF + +Q Sbjct: 52 MKDSDKNNDGRIDFDEFLKMMEGVQ 76 >2QFE-A nrPDB Length = 148 Score = 41.9 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 31/144 (21%) Query: 360 KMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQ 419 +++G W G +AGGC N+ T NP Y +E+ L+ L Sbjct: 26 RINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTG----------PLLIEL-------- 66 Query: 420 RKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPP 479 G +++GF + V G H FL + + F L E+ N +P Sbjct: 67 --RGPRQYSVGFEVVTV--STLGDPGPH----GFLRKSSGDYRCGFCYL-ELEN---IPS 114 Query: 480 GEYILVPSTFEPNKDGDFCIRVFS 503 G + ++PSTF P ++G F + S Sbjct: 115 GIFNIIPSTFLPKQEGPFFLDFNS 138 >2JUL-A nrPDB Length = 256 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 25/184 (13%), Positives = 66/184 (35%), Gaps = 35/184 (19%) Query: 514 DEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFS 573 D+++A + ++ ++ +R F + + I + + F Sbjct: 80 DQLQA---QTKFTKKELQSLYRG-FKNECPTGL-VDEDTFKLIYSQFFPQGDATTYAHF- 133 Query: 574 IETCKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEM 627 + + D+DG+G + ++F + + + +K + + D+++ G + EM Sbjct: 134 ------LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEM 187 Query: 628 RKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTI 687 ++ M + I+ A LE + + F+++D G + Sbjct: 188 LAIMKSIYDMMGRHTYP-ILREDAP----------------LEHVERFFQKMDRNQDGVV 230 Query: 688 ELDL 691 +D Sbjct: 231 TIDE 234 >2LCP-A nrPDB Length = 190 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 22/174 (12%), Positives = 54/174 (31%), Gaps = 32/174 (18%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 +E ++ ++ ++ A Q I ++ K F + ++ D Sbjct: 23 TEKEVQQWYKGFIKDCP--SGQLDAAGFQKIYKQFFPFGDPTKFATF-------VFNVFD 73 Query: 586 SDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMP 639 + G++ EF + +K + ++ D+D G + EM Sbjct: 74 ENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEM------------ 121 Query: 640 CQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 ++ A + ++ + + +IF +D G + L Sbjct: 122 ---LDIVDAIYQMVGNTVELPE--EENTPEKRVDRIFAMMDKNADGKLTLQEFQ 170 Score = 36.5 bits (83), Expect = 0.038, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 46/115 (40%), Gaps = 8/115 (6%) Query: 490 EPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGE-DAEI 548 +P K F VF E K + I+A S +D+ R F + D I Sbjct: 60 DPTKFATFVFNVFDENKDGRIEFSEFIQA---LSVTSRGTLDEKLRWAFKLYDLDNDGYI 116 Query: 549 SAFELQTILR---RVLAKRQDIKSDGFSIET-CKIMVDMLDSDGSGKLGLKEFYI 599 + E+ I+ +++ ++ + + E + M+D + GKL L+EF Sbjct: 117 TRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQE 171 >2Q4U-A nrPDB Length = 272 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 74/192 (38%), Gaps = 33/192 (17%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG-FSIETCKIMVDM 583 I ++DD FR + +L +D +I+ +Q I ++ D DG IE M+ Sbjct: 28 IEGKELDDFFRHMLKKLQPKD-KITDERVQQI-KKSFMSAYDATFDGRLQIEELANMI-- 83 Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF------- 636 L + + L + L + ++ KI+R+ D D SG +++ E++ L++ Sbjct: 84 LPQEENFLLIFRREAPLDNSV-EFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIP 142 Query: 637 --KMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLF------------------KIF 676 K+ ++ + +D ++ R L E KIF Sbjct: 143 PNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIF 202 Query: 677 KQLDPENTGTIE 688 D TG +E Sbjct: 203 AHYDVSRTGALE 214 Score = 36.5 bits (83), Expect = 0.045, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 54/151 (35%), Gaps = 30/151 (19%) Query: 542 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 601 A ISA EL+ L+ + + + E M+ + D + G+L L + + Sbjct: 115 ADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARIL 174 Query: 602 T------------------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLH 643 + + ++KI+ DV R+G + E+ +++ Sbjct: 175 ALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDM--------- 225 Query: 644 QVIVARFADDQLIIDFDNFVRCLVRLETLFK 674 + + R + D D F CL+ + K Sbjct: 226 -MELVRPSISGG--DLDKFRECLLTHCDMNK 253 >5ZOR-A nrPDB Length = 149 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/142 (11%), Positives = 45/142 (31%), Gaps = 45/142 (31%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKI------------------------------ 604 E + ++ D+DGSG + +E + + Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEF 66 Query: 605 --------------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQ-LHQVIVAR 649 ++ K ++ D+D+ G ++ +++ + G L ++I Sbjct: 67 ERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAEA 126 Query: 650 FADDQLIIDFDNFVRCLVRLET 671 D + F+ F ++++ Sbjct: 127 DEDGDGEVSFEEFKSVMMQMRG 148 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 11/95 (11%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPCQLHQVIVARFADD-QLIIDFDNF 662 ++ ++ + D D SG +++ EM A++ GF +P + V + +I++ F Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEF 66 Query: 663 VRCLVRL--------ETLFKIFKQLDPENTGTIEL 689 R +V+ E + K F+ D + G I Sbjct: 67 ER-MVKSRMAQKDSPEEVLKAFQLFDLDKKGKISF 100 Score = 32.3 bits (72), Expect = 0.68, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 24/68 (35%), Gaps = 6/68 (8%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK------YQKIYREIDVDRSGTMNSYE 626 S E + D D GK+ + + + Q++ E D D G ++ E Sbjct: 79 SPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFEE 138 Query: 627 MRKALEEA 634 + + + Sbjct: 139 FKSVMMQM 146 >5TBY-C nrPDB Length = 195 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 592 LGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 + + F + I + + + R D + +GT+ E+R L G ++ Sbjct: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 Query: 643 HQVIVARFADDQLIIDFDNFVR 664 + ++A D I+++ FV+ Sbjct: 169 VEKLMAGQEDSNGCINYEAFVK 190 >2W4G-C nrPDB Length = 145 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 35/83 (42%), Gaps = 9/83 (10%) Query: 591 KLGLKEFYILWTK---------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQ 641 K+ +EF + + + + R D + +GT+ E+R L G KM + Sbjct: 58 KITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEE 117 Query: 642 LHQVIVARFADDQLIIDFDNFVR 664 + ++ D I+++ FV+ Sbjct: 118 EVEELMKGQEDSNGCINYEAFVK 140 >1BJF-A nrPDB Length = 193 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 44/129 (34%), Gaps = 26/129 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPC 640 SG L ++EF ++ Y + ++R D + GT++ E AL K+ Sbjct: 40 SGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQ 99 Query: 641 QLHQVIVARFADDQLIIDFDNFVRCLVRLETLF------------------KIFKQLDPE 682 +L D I + + + + KIF+Q+D Sbjct: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 683 NTGTIELDL 691 G + L+ Sbjct: 160 RDGKLSLEE 168 Score = 29.6 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 18/70 (25%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKY------------------QKIYREIDVDRSGTMN 623 M D DG+G + E + I K +KI+R++D +R G ++ Sbjct: 106 SMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLS 165 Query: 624 SYEMRKALEE 633 E + + Sbjct: 166 LEEFIRGAKS 175 >4P5W-A nrPDB Length = 411 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 19/128 (14%), Positives = 48/128 (37%), Gaps = 14/128 (10%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK----YQKIYREIDVDRSGTMNSYEMR 628 + +T +++ ++D G + +EF + + + ++ D G + +++ Sbjct: 76 NPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVK 135 Query: 629 KALEEAG------FKMPCQLHQVIVARFADDQLIIDFDNFVRCL--VRLETLFKIFKQLD 680 + + F + Q+ + L + F + L ++LE + F Q D Sbjct: 136 QVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLT--YAEFTQFLLEIQLEHAKQAFVQRD 193 Query: 681 PENTGTIE 688 TG + Sbjct: 194 NARTGRVT 201 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 8/50 (16%), Positives = 14/50 (28%), Gaps = 4/50 (8%) Query: 650 FADDQLIIDFDNFVRCLVRLET----LFKIFKQLDPENTGTIELDLISWL 695 +I F FV L F+ D G + + + + Sbjct: 88 DQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQV 137 >1OZS-A nrPDB Length = 73 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFV 663 ++ ++R D + G ++ E++ L+ G + + +++ ++ ID+D F+ Sbjct: 7 EELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFL 66 Query: 664 RCLVRLE 670 + +E Sbjct: 67 EFMKGVE 73 Score = 31.5 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 35/80 (43%), Gaps = 11/80 (13%) Query: 526 SEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 585 SE+++ D FR +F + A D I EL+ +L+ + + + + ++ D Sbjct: 5 SEEELSDLFR-MFDKNA--DGYIDLEELKIMLQ--------ATGETITEDDIEELMKDGD 53 Query: 586 SDGSGKLGLKEFYILWTKIQ 605 + G++ EF ++ Sbjct: 54 KNNDGRIDYDEFLEFMKGVE 73 Score = 29.6 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 26/62 (41%), Gaps = 6/62 (9%) Query: 571 GFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK------YQKIYREIDVDRSGTMNS 624 G S E + M D + G + L+E I+ + +++ ++ D + G ++ Sbjct: 3 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 625 YE 626 E Sbjct: 63 DE 64 >6FSA-D nrPDB Length = 199 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 588 GSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 S + F + I + + + R D + +GT+ E+R L G K+ Sbjct: 109 NSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKL 168 Query: 639 PCQLHQVIVARFADDQLIIDFDNFVR 664 + ++A D I+++ FV+ Sbjct: 169 TEDEVEKLMAGQEDSNGCINYEAFVK 194 >2PMY-A nrPDB Length = 91 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 569 SDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ----KYQKIYREIDVDRSGTMNS 624 DG + + + D++ SG+L +EF L T+++ + +++ +D DR G + Sbjct: 21 GDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITF 80 Query: 625 YEMRKAL 631 E + Sbjct: 81 QEFARGF 87 >2LVV-A nrPDB Length = 226 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 7/62 (11%) Query: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNS 624 + I +M D +D DGS L L+EF K++++ ++ EID + SG + Sbjct: 130 YDIFELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTF 189 Query: 625 YE 626 E Sbjct: 190 DE 191 Score = 32.3 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 37/103 (35%), Gaps = 19/103 (18%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGF----KMPCQLHQVIVARFA---------DDQL 655 +++++ D + +G + E+ G + L ++ F Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGC--YGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVG 112 Query: 656 IIDFDNFVRCLVRLETLFKIFK---QLDP-ENTGTIELDLISW 694 D F+ + L ++ IF+ D + G++ L+L + Sbjct: 113 EEDLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEF 155 >2E30-A nrPDB Length = 195 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 67/183 (36%), Gaps = 20/183 (10%) Query: 506 KADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQ 565 +A D+E+E +E S I + R + GE+ +S + Q I + Sbjct: 4 RASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLG 63 Query: 566 DIKSDGFSIET---------CKIMVD---MLDSDGSGKLGLKEFYILWTKIQKYQKIYRE 613 D + F E + + + D++ S + E L ++ K +R Sbjct: 64 DRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPE--PLNSRSNKLHFAFRL 121 Query: 614 IDVDRSGTMNSYEMRKALEEA-GFKMPCQLHQVIVAR-----FADDQLIIDFDNFVRCLV 667 D+D+ ++ E+ + L G + + I R D I F FV+ L Sbjct: 122 YDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLE 181 Query: 668 RLE 670 +++ Sbjct: 182 KVD 184 >2M97-A nrPDB Length = 69 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIV-ARFADDQLIIDFDNFV 663 ++ + +R D D +G ++ E + G ++ + I D IDFD F+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 Query: 664 RCL 666 + + Sbjct: 63 KMM 65 Score = 32.3 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 27/58 (46%), Gaps = 6/58 (10%) Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQ------KIYREIDVDRSGTMNSYEMRKALEEA 634 + D DG+G + +EF + + +I+ + D D++G ++ E K +E Sbjct: 11 IFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMMENV 68 >2L2E-A nrPDB Length = 190 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 49/129 (37%), Gaps = 26/129 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KMPC 640 SG L EF ++ + + + ++ D D++G ++ E AL ++ Sbjct: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 Query: 641 QLHQVIVARFADDQLIIDFDNFVRC----------LVRL--------ETLFKIFKQLDPE 682 +L D+ +I +D +R +V+L + + KIF +D Sbjct: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 Query: 683 NTGTIELDL 691 G + L+ Sbjct: 160 KDGQLTLEE 168 Score = 35.4 bits (80), Expect = 0.099, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 10/99 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQ--VIVARFADDQLIIDF 659 ++Q++ K + SG +N E +K ++ V AD IDF Sbjct: 25 KELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 Query: 660 DNFVRCLVRL------ETLFKIFKQLDPENTGTIELDLI 692 F+ L + L F+ D +N G I D + Sbjct: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 10/114 (8%) Query: 490 EPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGED--AE 547 +P+ ++ VF K Y + I A S +++D F QL D Sbjct: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICA---LSVTSRGELNDKLIWAF-QLYDLDNNGL 115 Query: 548 ISAFELQTILR---RVLAKRQDIKSDGFSIET-CKIMVDMLDSDGSGKLGLKEF 597 IS E+ I+ +++ + D + E + +M+D + G+L L+EF Sbjct: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 >2BEC-A nrPDB Length = 202 Score = 40.0 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Query: 600 LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKMPCQLHQVIVAR-----FADD 653 L ++ K ++ D+DR G ++ +EM + L G ++ + + I R D Sbjct: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 Query: 654 QLIIDFDNFVRCLVRLE 670 + F F + L +++ Sbjct: 169 DGAVSFVEFTKSLEKMD 185 Score = 31.9 bits (71), Expect = 0.98, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 37/118 (31%), Gaps = 34/118 (28%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRK----ALEEAGFKMPCQLHQVIVARFADDQLII 657 + + +R +D ++ G ++ ++++ A+ G ++ F D + Sbjct: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF-------FPDGSQRV 78 Query: 658 DFDNFVRCLVRLETLFK-----------------------IFKQLDPENTGTIELDLI 692 DF FVR L + F+ D + G I + Sbjct: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 >2JU0-A nrPDB Length = 190 Score = 40.0 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 42/118 (35%), Gaps = 23/118 (19%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 633 + + D D +G + +EF + + +K + D++ G + EM + Sbjct: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 Query: 634 AGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDL 691 +KM + ++ + + + KIFK +D G I LD Sbjct: 128 V-YKM---MGSMVTLNEDEATPEM-------------RVKKIFKLMDKNEDGYITLDE 168 >1N2D-A nrPDB Length = 148 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 37/103 (35%), Gaps = 16/103 (15%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFA--DDQLIIDFDNFVRC 665 + I+ D G + + L G+ QL Q I+ + D + D + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQ-ITG 65 Query: 666 LVRL-------------ETLFKIFKQLDPENTGTIELDLISWL 695 L+ + E K F+ D E+TG + + + ++ Sbjct: 66 LIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYM 108 Score = 35.4 bits (80), Expect = 0.094, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFD 660 K + + K ++ D + +G ++ ++R L G K+ ++ +++ D ID+ Sbjct: 80 AKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYK 139 Query: 661 NFVRCLVR 668 F+ ++R Sbjct: 140 KFIEDVLR 147 >3DTP-E nrPDB Length = 196 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 38/101 (37%), Gaps = 7/101 (6%) Query: 589 SGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA 648 SG F ++Q++++ ++ ID D+ G ++ ++R + G Q +VA Sbjct: 43 SGSNVFAMFTQ--HQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVA 100 Query: 649 RFADDQL----IIDFDNFVRCLVRLETLFKIFKQLDPENTG 685 + F + + + + F D E G Sbjct: 101 EAPGPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDG 140 >5I2L-A nrPDB Length = 120 Score = 39.2 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 33/74 (44%), Gaps = 9/74 (12%) Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLH----QVIVAR 649 KEF +I+ +K++++ D R G ++ E++ +E+ G Q H +I Sbjct: 22 FKEFSR--KQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLG---APQTHLGLKNMIKEV 76 Query: 650 FADDQLIIDFDNFV 663 D + F F+ Sbjct: 77 DEDFDSKLSFREFL 90 Score = 32.7 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 10/84 (11%) Query: 521 EEFDISEDDIDDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKI 579 E + S I D ++F Q AG D I EL+ ++ ++ A + + K Sbjct: 21 EFKEFSRKQIKD-MEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHL--------GLKN 71 Query: 580 MVDMLDSDGSGKLGLKEFYILWTK 603 M+ +D D KL +EF +++ K Sbjct: 72 MIKEVDEDFDSKLSFREFLLIFRK 95 >5PAL-A nrPDB Length = 109 Score = 38.8 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 33/81 (40%), Gaps = 8/81 (9%) Query: 590 GKLGLKEFYILWTKIQK----YQKIYREIDVDRSGTMNSYEMRKALE---EAGFKMPC-Q 641 G K F+ L K ++++ +D D+SG + E++ L+ G + + Sbjct: 22 GTFDYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTE 81 Query: 642 LHQVIVARFADDQLIIDFDNF 662 ++ A +D I D F Sbjct: 82 TKALLAAGDSDHDGKIGADEF 102 Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 6/71 (8%) Query: 531 DDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGS 589 D + +F L + I EL+ +L+ A +D+ + K ++ DSD Sbjct: 40 DAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDL-----NDTETKALLAAGDSDHD 94 Query: 590 GKLGLKEFYIL 600 GK+G EF + Sbjct: 95 GKIGADEFAKM 105 >3J04-B nrPDB Length = 143 Score = 38.8 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 46/105 (43%), Gaps = 10/105 (9%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 661 ++IQ++++ + ID +R G ++ ++ L G + + ++ ++ I+F Sbjct: 4 SQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMM---SEAPGPINFTM 60 Query: 662 FVRCL-VRL------ETLFKIFKQLDPENTGTIELDLISWLCFSV 699 F+ +L + + F D E +G I D + L ++ Sbjct: 61 FLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTM 105 Score = 36.1 bits (82), Expect = 0.050, Method: Composition-based stats. Identities = 21/146 (14%), Positives = 46/146 (31%), Gaps = 21/146 (14%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 F+ F + D I +L +L + D +G + S+ G Sbjct: 7 QEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEG------------MMSEAPG 54 Query: 591 KLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLH 643 + F ++ + + + D + SG ++ +R+ L G + + Sbjct: 55 PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEV 114 Query: 644 QVIVA-RFADDQLIIDFDNFVRCLVR 668 + D + ++ F R L Sbjct: 115 DEMYREAPIDKKGNFNYVEFTRILKH 140 >2N8Y-A nrPDB Length = 153 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 29/78 (37%), Gaps = 6/78 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM------PCQLHQVIVARFADDQLII 657 + +++ + D D SGT+ E + L G+ + + +++ + ++ Sbjct: 9 MNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVV 68 Query: 658 DFDNFVRCLVRLETLFKI 675 F F+ + R Sbjct: 69 TFQAFIDFMSRETADTDT 86 >2I94-A nrPDB Length = 202 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 16/105 (15%) Query: 589 SGKLGLKEFYILWTKI------QKY-QKIYREIDVDRSGTMNSYEMRKAL--EEAGFKMP 639 SG++ +EF +++K + Y Q ++R D + GT++ E AL AG K Sbjct: 41 SGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAG-KTN 99 Query: 640 CQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENT 684 +L D I + LE + IFK + PE+T Sbjct: 100 QKLEWAFSLYDVDGNGTISKNE------VLEIVTAIFKMISPEDT 138 >5ZGM-A nrPDB Length = 110 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 590 GKLGLKEFYILW----TKIQKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-Q 641 G K F+ L + ++++ +D D+SG + E++ K G + + Sbjct: 23 GTFDYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTE 82 Query: 642 LHQVIVARFADDQLIIDFDNF 662 ++ A +D I D F Sbjct: 83 TKALLAAGDSDHDGKIGADEF 103 Score = 33.5 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 544 EDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL 600 + I EL+++L+ A +D+ S K ++ DSD GK+G EF + Sbjct: 55 QSGFIEEEELKSVLKGFSAHGRDL-----SDTETKALLAAGDSDHDGKIGADEFAKM 106 >1SJJ-A nrPDB Length = 863 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 37/97 (38%), Gaps = 9/97 (9%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 + +++ + D ++G M+ + R L G+ M + +++ + ++ F F Sbjct: 724 MNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTFQAF 783 Query: 663 VRCLVRLETLFKI-------FKQLDPENTGTIELDLI 692 + + R FK L + I +D + Sbjct: 784 IDFMSRETADTDTADQVMASFKILAGD-KNYITVDEL 819 >2OS8-B nrPDB Length = 157 Score = 37.7 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 45/116 (38%), Gaps = 10/116 (8%) Query: 583 MLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQL 642 M D SG L + +IQ+ ++ + ID +R G ++ ++++ G + P Sbjct: 1 MADKAASGVLT----KLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLG-RTPDDK 55 Query: 643 HQVIVARFADDQLIID-----FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 + + A L F + + ET+ F D +T + ++ I Sbjct: 56 ELTAMLKEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIK 111 >1DGU-A nrPDB Length = 183 Score = 37.3 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 55/170 (32%), Gaps = 20/170 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +++ +I RR L E + + + + ++K++ F C++ Sbjct: 14 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 73 Query: 585 DSDGSGKLGLKEFYILWTKIQKYQK-------IYREIDVDRSGTMNSYEMRKALE----- 632 D L ++F L + +R D D GT+N ++ + + Sbjct: 74 AKD---SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 130 Query: 633 -----EAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFK 677 + +M + ++ D I+ F + R FK Sbjct: 131 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 180 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 11/142 (7%) Query: 479 PGEYILVPSTFEPNKDGDFCIRVFSEKKA-DYQAVDDEIEANLEEFDISEDDIDDGFR-R 536 P E IL + N + RVFS A D + +D ++ D + DI + R Sbjct: 46 PFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFR 105 Query: 537 LFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML----DSDGSGKL 592 +F +D ++ +L ++ + + +D + S K ++D + D D G + Sbjct: 106 IFD--FDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNILEESDIDRDGTI 160 Query: 593 GLKEFYILWTKIQKYQKIYREI 614 L EF + ++ + ++ + Sbjct: 161 NLSEFQHVISRSPDFASSFKIV 182 >1ZFS-A nrPDB Length = 93 Score = 36.9 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Query: 543 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 G+ ++S EL+ +L+ L+ D++ D + ++ LD +G G++ +EF +L Sbjct: 23 GDKYKLSKKELKDLLQTELSSFLDVQKDA---DAVDKIMKELDENGDGEVDFQEFVVLVA 79 Query: 603 KIQ 605 + Sbjct: 80 ALT 82 >2LM5-A nrPDB Length = 214 Score = 36.9 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 55/170 (32%), Gaps = 20/170 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +++ +I RR L E + + + + ++K++ F C++ Sbjct: 45 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 104 Query: 585 DSDGSGKLGLKEFYILWTKIQKYQK-------IYREIDVDRSGTMNSYEMRKALE----- 632 D L ++F L + +R D D GT+N ++ + + Sbjct: 105 AKD---SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 161 Query: 633 -----EAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFK 677 + +M + ++ D I+ F + R FK Sbjct: 162 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 211 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 11/142 (7%) Query: 479 PGEYILVPSTFEPNKDGDFCIRVFSEKKA-DYQAVDDEIEANLEEFDISEDDIDDGFR-R 536 P E IL + N + RVFS A D + +D ++ D + DI + R Sbjct: 77 PFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFR 136 Query: 537 LFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML----DSDGSGKL 592 +F +D ++ +L ++ + + +D + S K ++D + D D G + Sbjct: 137 IFD--FDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNILEESDIDRDGTI 191 Query: 593 GLKEFYILWTKIQKYQKIYREI 614 L EF + ++ + ++ + Sbjct: 192 NLSEFQHVISRSPDFASSFKIV 213 >3PAT-A nrPDB Length = 110 Score = 36.9 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFD 660 +K+++ ID D SG + E++ K+ G + + + A D I D Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGID 101 Query: 661 NF 662 F Sbjct: 102 EF 103 Score = 35.8 bits (81), Expect = 0.071, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 6/73 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 + +++F + + I EL+ +L+ A +D+ K + D DG G Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTD-----AETKAFLKAADKDGDG 96 Query: 591 KLGLKEFYILWTK 603 K+G+ EF L + Sbjct: 97 KIGIDEFETLVHE 109 >1S36-A nrPDB Length = 195 Score = 36.9 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 14/70 (20%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKYQKI----------YREIDVDRSGTMNSYEMRKAL 631 D+ D DGSG + L E W K I +R D+D SG ++ EM + Sbjct: 120 DIFDKDGSGTITLDE----WKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTRQH 175 Query: 632 EEAGFKMPCQ 641 + + + Sbjct: 176 LGFWYTLDPE 185 Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 602 TKIQKY-QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDF 659 T I+++ ++ D D SGT+ E + + +G + + D+ +D Sbjct: 109 TLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDV 168 Query: 660 DNFVR 664 D R Sbjct: 169 DEMTR 173 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 34/119 (28%) Query: 604 IQKYQKIYREIDVDRSGTMNSYE-MRKALEEAGFKM---PCQL--HQVIVARFADD---- 653 I++++ ++ +D++ +G + E + KA ++ K+ P Q HQV V F Sbjct: 19 IKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGME 78 Query: 654 -QLIIDFDNFVRCLVRL--------------------ETLFKIFKQLDPENTGTIELDL 691 I F F+ +L + +F IF D + +GTI LD Sbjct: 79 YGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIF---DKDGSGTITLDE 134 >1QLS-A nrPDB Length = 99 Score = 36.9 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDA---EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 +F + AG D +IS E + LA + D ++ M+ LD D G+L Sbjct: 18 IFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLD---RMMKKLDLDSDGQLD 74 Query: 594 LKEFYIL 600 +EF L Sbjct: 75 FQEFLNL 81 >1JF0-A nrPDB Length = 195 Score = 36.9 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 582 DMLDSDGSGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEA 634 D+ D DGSG + L E+ + +I +K ++ D+D SG ++ EM + Sbjct: 120 DIFDKDGSGTITLDEWKA-YGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTRQHLGF 178 Query: 635 GFKMPCQ 641 + + + Sbjct: 179 WYTLDPE 185 Score = 32.7 bits (73), Expect = 0.63, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 27/89 (30%), Gaps = 18/89 (20%) Query: 594 LKEFYILWTK----------------IQKY-QKIYREIDVDRSGTMNSYEMRKALEEAGF 636 EF W I+++ ++ D D SGT+ E + +G Sbjct: 85 FPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGRISGI 144 Query: 637 KMPCQ-LHQVIVARFADDQLIIDFDNFVR 664 + + D+ +D D R Sbjct: 145 SPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 >2NLN-A nrPDB Length = 108 Score = 36.9 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 608 QKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 + I+R ID D+SG ++ E++ + + ++ + ++ A D I D F Sbjct: 44 KDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEF 102 Score = 32.3 bits (72), Expect = 0.83, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +S + D FR + + + EL+ L++ + +++ K ++D Sbjct: 38 MSASQVKDIFRFIDND---QSGYLDGDELKYFLQKFQSDARELTES-----ETKSLMDAA 89 Query: 585 DSDGSGKLGLKEFYILWTK 603 D+DG GK+G EF + Sbjct: 90 DNDGDGKIGADEFQEMVHS 108 >1NYA-A nrPDB Length = 176 Score = 36.5 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 49/116 (42%), Gaps = 9/116 (7%) Query: 530 IDDGFRRLFAQLA-----GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 + + F LF LA G D ++ + + ++ ++ + + K +V M Sbjct: 52 LKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMC 111 Query: 585 DSDGSGKLGLKEFYILWTKIQKYQ----KIYREIDVDRSGTMNSYEMRKALEEAGF 636 D + G++ EF T + + + + ++D + +G ++ E+ A+ + F Sbjct: 112 DKNADGQINADEFAAWLTALGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDFHF 167 >3TS5-B nrPDB Length = 161 Score = 35.8 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 45/115 (39%), Gaps = 7/115 (6%) Query: 585 DSDGSGKLGLKEFYILWTKI-QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLH 643 D + + + F L K+ Q+ ++ + ID +R G ++ ++++ G + P Sbjct: 2 DKERAQRATSNVFARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLG-RTPDDKE 60 Query: 644 QVIVARFADDQLIID-----FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 + + A L F + + ET+ F D +T + ++ I Sbjct: 61 LTAMLKEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIK 115 >6EPA-A nrPDB Length = 187 Score = 35.8 bits (81), Expect = 0.062, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 40/115 (34%), Gaps = 24/115 (20%) Query: 583 MLDSDGSGKLGLKEFYILW------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + D + G + +EF +K +R DVD G + EM + Sbjct: 71 VFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEM--------Y 122 Query: 637 KMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDL 691 + ++Q++ + + + + KIF Q+D + + L+ Sbjct: 123 NIVDAIYQMVGQQPQTEDENTPQ----------KRVDKIFDQMDKNHDDRLTLEE 167 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 44/114 (38%), Gaps = 7/114 (6%) Query: 490 EPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQL-AGEDAEI 548 +P+K RVF E ++ I A S ++D+ F D I Sbjct: 60 DPSKFASLVFRVFDENNDGAIEFEEFIRA---LSITSRGNLDEKLHWAFRLYDVDNDGYI 116 Query: 549 SAFELQTILR---RVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYI 599 + E+ I+ +++ ++ + + + + D +D + +L L+EF Sbjct: 117 TREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFRE 170 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 7/61 (11%) Query: 639 PCQLHQVIVARFA-DDQLIIDFDNFVRCLVRL------ETLFKIFKQLDPENTGTIELDL 691 P + ++ F ++ I+F+ F+R L E L F+ D +N G I + Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 692 I 692 + Sbjct: 121 M 121 >3DD4-A nrPDB Length = 229 Score = 35.8 bits (81), Expect = 0.066, Method: Composition-based stats. Identities = 13/120 (10%), Positives = 40/120 (33%), Gaps = 19/120 (15%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 633 + + D+D +G + ++F + + +K + D+++ G + EM ++ Sbjct: 107 LFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 634 AGFKM-------------PCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLD 680 M + + ++ D F+ + E + + + + Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFE 226 >3KPX-A nrPDB Length = 198 Score = 35.8 bits (81), Expect = 0.067, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 578 KIMVDMLDSDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + + D+ D DGSG + L E+ + + +K ++ D+D SG ++ EM + Sbjct: 119 EAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 >2KYF-A nrPDB Length = 108 Score = 35.8 bits (81), Expect = 0.067, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 30/61 (49%), Gaps = 4/61 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALE--EAGFKM--PCQLHQVIVARFADDQLIIDFDN 661 + ++I+R +D D+SG + E++ L+ E+G ++ + + A D I + Sbjct: 42 QLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGKIGAEE 101 Query: 662 F 662 F Sbjct: 102 F 102 Score = 29.6 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 533 GFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGK 591 + +F L + I EL+ L+R + + + + K + D DG GK Sbjct: 42 QLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTAS-----ETKTFLAAADHDGDGK 96 Query: 592 LGLKEFYIL 600 +G +EF + Sbjct: 97 IGAEEFQEM 105 >2EC6-B nrPDB Length = 133 Score = 35.8 bits (81), Expect = 0.073, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 38/95 (40%), Gaps = 6/95 (6%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID----- 658 +Q+ ++ + ID +R G ++ ++++ G + P + + A L Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLG-RTPDDKELTAMLKEAPGPLNFTMFLSI 59 Query: 659 FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 F + + ET+ F D + T + ++ I Sbjct: 60 FSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIK 94 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 31/94 (32%), Gaps = 8/94 (8%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKA 630 K + ML + G L F +++ + + + D D + +N ++ Sbjct: 38 KELTAML-KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDL 96 Query: 631 LEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVR 664 LE G ++ + D+ FV Sbjct: 97 LENMGDNFNKDEMRMTFKEAPVEGGKFDYVRFVA 130 >1TTX-A nrPDB Length = 109 Score = 35.8 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 28/62 (45%), Gaps = 4/62 (6%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFD 660 + + ++R ID D+SG ++ E++ + E ++ + ++ A D I + Sbjct: 42 NQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAE 101 Query: 661 NF 662 F Sbjct: 102 EF 103 Score = 31.5 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 8/79 (10%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +S + + D FR + + + EL+ L++ + +++ K ++ Sbjct: 39 MSANQVKDVFRFIDND---QSGYLDEEELKFFLQKFESGARELTES-----ETKSLMAAA 90 Query: 585 DSDGSGKLGLKEFYILWTK 603 D+DG GK+G +EF + Sbjct: 91 DNDGDGKIGAEEFQEMVHS 109 >1JBA-A nrPDB Length = 204 Score = 35.4 bits (80), Expect = 0.081, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 44/121 (36%), Gaps = 18/121 (14%) Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKA 630 + M D++G + E+ + K + ++ D DR+G ++ E+ Sbjct: 61 VEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDI 120 Query: 631 LEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 690 +E +K+ V A+ Q + E + +IF +D G + L+ Sbjct: 121 VESI-YKLK---KACSVEVEAEQQGKLLTPE--------EVVDRIFLLVDENGDGQLSLN 168 Query: 691 L 691 Sbjct: 169 E 169 >4I5L-B nrPDB Length = 413 Score = 35.4 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 22/111 (19%) Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMR------------KALEEAGFK-MPCQ 641 +E T I+ + +R +D+D G ++ +E+ A+E F+ CQ Sbjct: 265 EEDKKTPTSIEYW---FRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQ 321 Query: 642 LHQVIVARFADDQLIIDFDNFVRC---LVRLETLFKIFKQLDPENTGTIEL 689 + ++ R + I + RC V +T F I K LD E I L Sbjct: 322 MLDLVKPR---TEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQISL 369 >1C7W-A nrPDB Length = 81 Score = 35.4 bits (80), Expect = 0.092, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK--MPCQLHQVIVARFADDQLIIDFDNF 662 ++ + ++ D + G ++ E + +++ G + ++ + + D +ID F Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 663 V 663 + Sbjct: 68 M 68 Score = 34.6 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 29/67 (43%), Gaps = 7/67 (10%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ-------KYQKIYREIDVDRSGTMNSYEM 627 E + D++G G + EF + K+ + ++ +E D D +G ++ E Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 628 RKALEEA 634 ++++ Sbjct: 68 MDLIKKS 74 >1YIO-A nrPDB Length = 208 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 485 VPSTFEPNKDG--DFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLA 542 +P T K G +F + F E++A A++ ++ N E E D +LF+ L Sbjct: 88 IPMTVRAMKAGAIEFLPKPF-EEQALLDAIEQGLQLNAERRQARET--QDQLEQLFSSLT 144 Query: 543 GEDAEISAFELQTILRRVLA 562 G + ++ ++ ++ + +A Sbjct: 145 GREQQVLQLTIRGLMNKQIA 164 >5B7X-A nrPDB Length = 156 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 32/95 (33%), Gaps = 8/95 (8%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 661 QK + + D D G ++ ++ + G + FA + + Sbjct: 10 ANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGETFQIEQ 69 Query: 662 FVRCLVRLET--------LFKIFKQLDPENTGTIE 688 F + R ++ L K F+ D + G I+ Sbjct: 70 FELIMEREQSKPDTREIKLRKAFEVFDQDKDGKIK 104 >1DFK-Y nrPDB Length = 139 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID--- 658 +IQ+ ++ + IDVDR G ++ +++ E+ G + P + + A L Sbjct: 4 KQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLG-RAPDDKELTAMLKEAPGPLNFTMFL 62 Query: 659 --FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 F + + ET+ F D + T + ++ I Sbjct: 63 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIK 99 >1NSH-A nrPDB Length = 101 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDAE---ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 +F + AG+D +S E + + LA + D ++ M+ LD + G+L Sbjct: 16 VFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLD---RMMKKLDLNSDGQLD 72 Query: 594 LKEFYIL 600 +EF L Sbjct: 73 FQEFLNL 79 >1B7T-Y nrPDB Length = 156 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIID--- 658 +IQ+ ++ + IDVDR G ++ +++ E+ G + P + + A L Sbjct: 15 KQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLG-RAPDDKELTAMLKEAPGPLNFTMFL 73 Query: 659 --FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLIS 693 F + + ET+ F D + T + ++ I Sbjct: 74 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIK 110 >5XOP-A nrPDB Length = 66 Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 610 IYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNFVRC 665 +++EIDV+ G ++ E++ + + QL Q+I D IDF+ F + Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 25/58 (43%), Gaps = 6/58 (10%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRK 629 + + +D +G G + +E +K + + I++ ID D G ++ E K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAK 60 >1RTP-1 nrPDB Length = 109 Score = 35.0 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D +++F L + I EL +IL+ + +D+ S + K ++ D DG G Sbjct: 41 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDL-----SAKETKTLMAAGDKDGDG 95 Query: 591 KLGLKEFYIL 600 K+G++EF L Sbjct: 96 KIGVEEFSTL 105 Score = 30.0 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 23/59 (38%), Gaps = 4/59 (6%) Query: 608 QKIYREIDVDRSGTMNSYEMR---KALEEAGFKMP-CQLHQVIVARFADDQLIIDFDNF 662 +K++ +D D+SG + E+ K + + ++ A D I + F Sbjct: 44 KKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEF 102 >2LUC-A nrPDB Length = 105 Score = 34.6 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDA---EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 +F + AG+D +S E + + LA + D ++ M+ LD++ G+L Sbjct: 20 VFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLD---RMMKKLDTNSDGQLD 76 Query: 594 LKEFYIL 600 EF L Sbjct: 77 FSEFLNL 83 >2FCE-A nrPDB Length = 70 Score = 34.6 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFD 660 K + + K ++ D + +G ++ ++R L G K+ ++ +++ D ID+ Sbjct: 2 AKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYK 61 Query: 661 NFVRCLVR 668 F+ ++R Sbjct: 62 KFIEDVLR 69 >5VE9-A nrPDB Length = 91 Score = 34.6 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 1/57 (1%) Query: 611 YREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCL 666 +R ID D+ G + E + + F ++ V D ID+ FV L Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 29.2 bits (64), Expect = 7.1, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 21/54 (38%), Gaps = 6/54 (11%) Query: 584 LDSDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 +D D GK+ +EF T + + D D G ++ YE AL Sbjct: 36 IDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 >1G33-A nrPDB Length = 73 Score = 34.6 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D +++F L + I EL +IL+ + +D+ S + K ++ D DG G Sbjct: 5 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDL-----SAKETKTLMAAGDKDGDG 59 Query: 591 KLGLKEFYIL 600 K+G++EF L Sbjct: 60 KIGVEEFSTL 69 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 23/66 (34%), Gaps = 4/66 (6%) Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMP-CQLHQVIVARFADDQLI 656 +K++ +D D+SG + E+ K + + ++ A D Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGK 60 Query: 657 IDFDNF 662 I + F Sbjct: 61 IGVEEF 66 >5W1A-B nrPDB Length = 155 Score = 34.2 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 39/94 (41%), Gaps = 9/94 (9%) Query: 586 SDGSGKLGLKEFYILWTKIQKYQK---------IYREIDVDRSGTMNSYEMRKALEEAGF 636 K+ L EF ++++++K ++ + D + +GTM E++ AL G Sbjct: 55 KRNEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGE 114 Query: 637 KMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLE 670 + + + + A D + F + L R+ Sbjct: 115 SLDDEQVETLFADCMDPEDDEGFIPYSPFLARMC 148 >2D8N-A nrPDB Length = 207 Score = 34.2 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 16/103 (15%) Query: 589 SGKLGLKEFYILWTKI------QKY-QKIYREIDVDRSGTMNSYEMRKAL--EEAGFKMP 639 +G++ ++F ++ K + Y Q ++R D + GT++ E AL AG K Sbjct: 48 TGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAG-KTN 106 Query: 640 CQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPE 682 +L D I + LE + IFK + PE Sbjct: 107 QKLEWAFSLYDVDGNGTISKNE------VLEIVMAIFKMITPE 143 Score = 32.7 bits (73), Expect = 0.59, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 6/50 (12%) Query: 584 LDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEM 627 DS+ G L KE+ I QK + + DVD +GT++ E+ Sbjct: 80 FDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEV 129 >1CB1-A nrPDB Length = 78 Score = 33.8 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 597 +A G+ ++S EL+ +++ + +++ + LD +G G++ +EF Sbjct: 16 YAAKEGDPNQLSKEELKQLIQAEF---PSLLKGPRTLDD---LFQELDKNGDGEVSFEEF 69 Query: 598 YILWTKI 604 +L KI Sbjct: 70 QVLVKKI 76 >5ZH6-A nrPDB Length = 107 Score = 33.8 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 609 KIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNF 662 K++ +D DRSG + E++ + ++ + + + A +D I D F Sbjct: 44 KVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEF 101 >1V1G-A nrPDB Length = 222 Score = 33.8 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 62/162 (38%), Gaps = 40/162 (24%) Query: 571 GFSIETCKIMVDMLDSDGS-----GKLGLKEFYILWTKIQKYQK-----IYREIDVDRSG 620 F++E + + ++ S G + +EF + + + + I+ DV R+G Sbjct: 30 PFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNLFADRIFDVFDVKRNG 89 Query: 621 TMNSYEMRKALE----------------------EAGFKMPCQLHQVIVARFADDQLIID 658 + E ++L + GF +L +++VA + +L++ Sbjct: 90 VIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALLHESELVLS 149 Query: 659 FDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 700 D + +V K F Q D +N G I D+ W F L Sbjct: 150 ED-MIEVMVD-----KAFVQADRKNDGKI--DIDEWKDFVSL 183 >5XND-A nrPDB Length = 114 Score = 33.8 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEE--AGFK-MPC-QLHQVIVARFADDQLII 657 + +K + ID D+SG + E++ L+ AG + + + + A +D I Sbjct: 44 KSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKI 103 Query: 658 DFDNFVR 664 D F Sbjct: 104 GIDEFAA 110 >2L0P-A nrPDB Length = 94 Score = 33.8 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Query: 536 RLFAQLAGEDAE---ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592 +F +G++ + +S EL+ +L+ L+ D + D ++ ++ LD +G G++ Sbjct: 14 NVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKD---VDAVDKVMKELDENGDGEV 70 Query: 593 GLKEFYILWTKIQ 605 +E+ +L + Sbjct: 71 DFQEYVVLVAALT 83 >2K2A-A nrPDB Length = 70 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 18/30 (60%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 S E M+D +D+DGSG + +EF + T Sbjct: 37 SSEDLDAMIDEIDADGSGTVDFEEFMGVMT 66 >2KQY-A nrPDB Length = 108 Score = 33.5 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D +++F L + I ELQ L+ + + + S K + D+DG G Sbjct: 41 DQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTS-----AETKAFLAAGDTDGDG 95 Query: 591 KLGLKEFYIL 600 K+G++EF L Sbjct: 96 KIGVEEFQSL 105 Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 24/61 (39%), Gaps = 4/61 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFK----MPCQLHQVIVARFADDQLIIDFDN 661 + +K++ +D D+SG + E++ L+ + + A D I + Sbjct: 42 QIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIGVEE 101 Query: 662 F 662 F Sbjct: 102 F 102 >3GMC-A nrPDB Length = 415 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 43/112 (38%), Gaps = 19/112 (16%) Query: 277 SLQKLIRIRNPWGEVEW-TGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSF------- 328 S LIR+ P + E G W++ WN P + L + E ++ Sbjct: 211 SKDGLIRLIVPRMKKELGHGEWDNTIDMWNFW-PRVQRILYSPCNENELYLGLMAPAADP 269 Query: 329 ---------SDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTA 371 ++ + LE C + L + Y K++ TK+D +W RG A Sbjct: 270 RGSSVPIDLEVWVEMFPFLEPCLIEAAKLKTARYDKYETTKLD-SWTRGKVA 320 >1SL8-A nrPDB Length = 191 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQKYQ------KIYREIDVDRSGTMNSYEMRK 629 + D++D D +G + L E+ Q + +R D+D SG ++ EM + Sbjct: 114 LFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >5CPV-A nrPDB Length = 109 Score = 33.1 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 24/62 (38%), Gaps = 4/62 (6%) Query: 608 QKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFV 663 +K + ID D+SG + E++ + + + + + A +D I D F Sbjct: 45 KKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGKIGVDEFT 104 Query: 664 RC 665 Sbjct: 105 AL 106 >4OCI-A nrPDB Length = 146 Score = 33.1 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFAD 652 + + + +D D+ G + + E+R+ L G M ++ + D Sbjct: 66 FSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITDLFTFMGID 125 Query: 653 DQLIIDFDNFV 663 +Q ++ D+F+ Sbjct: 126 EQGVVKVDDFI 136 Score = 32.3 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 33/94 (35%), Gaps = 16/94 (17%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLI--IDFDNF 662 + ++ + D D G + E + G M I + + + + + ++ F Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMET---SAIASTYNSNSKVRGMSYELF 62 Query: 663 VRCLVRLETLFKIFKQ---------LDPENTGTI 687 C +L+ K F + LD + G I Sbjct: 63 TSCFSQLK--TKSFNKDEIKTAINVLDKDKKGFI 94 >1UHK-A nrPDB Length = 191 Score = 33.1 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQKYQ------KIYREIDVDRSGTMNSYEMRK 629 + D++D D +G + L E+ Q + +R D+D SG ++ EM + Sbjct: 114 LFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >2AUC-A nrPDB Length = 126 Score = 32.7 bits (73), Expect = 0.50, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 23/54 (42%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLI 656 +++ K++ D + SG + +M+ L G + Q + F+ + I Sbjct: 63 NMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSEDRI 116 >2QJ0-A nrPDB Length = 982 Score = 32.7 bits (73), Expect = 0.53, Method: Composition-based stats. Identities = 40/197 (20%), Positives = 72/197 (36%), Gaps = 23/197 (11%) Query: 482 YILVPS-----TFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRR 536 Y +PS ++ + DF +R + D + DE +NL E ++++D+ R Sbjct: 673 YYKIPSYKNQLIWQSQNNADFFVRFVARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARG 732 Query: 537 LFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKE 596 A E ELQT L A RQ S G + + + ++ D E Sbjct: 733 -----APPTREEEDKELQTRLAS--ASRQAKSSCGLA-DKSMKLFEIYSKDIPAAFVTPE 784 Query: 597 FYILWTKIQKY--------QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA 648 + Y + ++ +S + N ++ KAL + Q ++ Sbjct: 785 IVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQ--SEFIS 842 Query: 649 RFADDQLIIDFDNFVRC 665 A D+ + + FVR Sbjct: 843 AVAKDERSFNRNLFVRA 859 >1RK9-A nrPDB Length = 110 Score = 32.7 bits (73), Expect = 0.53, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSG 590 D +++F L + I EL IL+ +D+ S + K+++ D DG G Sbjct: 42 DDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDL-----SAKETKMLMAAGDKDGDG 96 Query: 591 KLGLKEFYIL 600 K+G+ EF L Sbjct: 97 KIGVDEFSTL 106 Score = 31.9 bits (71), Expect = 0.94, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 8/61 (13%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFK------MPCQLHQVIVARFADDQLIIDFDN 661 +K++ +D D+SG + E+ GF + ++ A D I D Sbjct: 45 KKVFHMLDKDKSGFIEEDEL--GFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDE 102 Query: 662 F 662 F Sbjct: 103 F 103 >1KQV-A nrPDB Length = 79 Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 525 ISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDML 584 +S + + +F + A ++ + + + + + + + +++ + + L Sbjct: 1 MSAKKSPEELKGIFEKYAAKEGDPNQLSKEELKLLLQTEFPSLLKGMSTLDE---LFEEL 57 Query: 585 DSDGSGKLGLKEFYILWTKI 604 D +G G++ +EF +L KI Sbjct: 58 DKNGDGEVSFEEFQVLVKKI 77 >2M7M-A nrPDB Length = 66 Score = 32.7 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 610 IYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR-FADDQLIIDFDNFVRC 665 +++EIDV+ G ++ E++ + + QL Q+I AD ID + F + Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Score = 31.9 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 26/58 (44%), Gaps = 6/58 (10%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRK 629 + + +D +G G + +E +K + + I++ ID D +G ++ E K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAK 60 >2I18-A nrPDB Length = 64 Score = 32.7 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRC 665 + +Y+ +DVD G + E+ ++ G ++ + ++ A+ I + F+ Sbjct: 6 GLKVLYKLMDVDGDGKLTKEEVTSFFKKHGI---EKVAEQVMKADANGDGYITLEEFLEF 62 Query: 666 LV 667 + Sbjct: 63 SL 64 Score = 29.2 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 578 KIMVDMLDSDGSGKLGLKEFYILWTK--IQKYQKIYREIDVDRSGTMNSYE 626 K++ ++D DG GKL +E + K I+K + + D + G + E Sbjct: 8 KVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEE 58 >1TIZ-A nrPDB Length = 67 Score = 32.7 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 6/65 (9%) Query: 576 TCKIMVDMLDSDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + K + + D + GKL L EF + + + K + EIDVD +G +N+ E Sbjct: 2 SAKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTS 61 Query: 630 ALEEA 634 +E+ Sbjct: 62 CIEKM 66 Score = 32.7 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 29/63 (46%), Gaps = 1/63 (1%) Query: 608 QKIYREIDVDRSGTMNSYEMRK-ALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666 ++++ + D ++ G ++ E R+ AL + + + + D ++ D F C+ Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSCI 63 Query: 667 VRL 669 ++ Sbjct: 64 EKM 66 >6AGH-A nrPDB Length = 339 Score = 32.3 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 46/230 (20%), Positives = 82/230 (35%), Gaps = 52/230 (22%) Query: 480 GEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRL-- 537 GEY + P DF V E ++E +++ DI+D + Sbjct: 41 GEYYMTPR--------DFLFSVMFE----------QMERKTSVKKLTKKDIEDTLSGIQT 82 Query: 538 ------FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGK 591 F + G+ IS E +L + GF + MLD+DG+ Sbjct: 83 AGCGSTFFRDLGDKGLISYTEYLFLLTILTKPH-----SGFHVA-----FKMLDTDGNEM 132 Query: 592 LGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARF- 650 + +EF+ L I K Q + + +G ++A+ + +++ + RF Sbjct: 133 IEKREFFKLQKIISK-QDDLMTVKTNETG------YQEAIVK-----EPEINTTLQMRFF 180 Query: 651 -ADDQLIIDFDNFVRCLVRLETLFK--IFKQLDPENTGTIELDLISWLCF 697 Q + + F R + L+T + F Q + + D WL F Sbjct: 181 GKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLF 230 >3CS1-A nrPDB Length = 219 Score = 32.3 bits (72), Expect = 0.68, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 50/132 (37%), Gaps = 24/132 (18%) Query: 584 LDSDGSGKLGLKEFYILWTKIQKYQKIYREIDV------DRSGTMNSYEMRKALEEAGFK 637 D + +GKL E Y ++ K + + D+S T+ S K E+ Sbjct: 57 FDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEF 116 Query: 638 MP-----CQLHQ------VIVARFADDQLIIDFDNFVRCLVRLETL-------FKIFKQL 679 + C ++ + A +++D + F R + +LE +FK+L Sbjct: 117 LEFRLMLCYIYDFFELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKEL 176 Query: 680 DPENTGTIELDL 691 D TG++ D Sbjct: 177 DKNGTGSVTFDE 188 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 13/101 (12%), Positives = 37/101 (36%), Gaps = 15/101 (14%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGF--KMPCQLHQVIVARFADDQ---------LII 657 +++++ D + +G + E+ E + ++ + F + Sbjct: 52 ELFKKFDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSE 111 Query: 658 DFDNFVRCLVRLETLFKIFK---QLDP-ENTGTIELDLISW 694 DF F+ + L ++ F+ D + +G + +D + Sbjct: 112 DFVEFLEFRLMLCYIYDFFELTVMFDEIDASGNMLVDEEEF 152 >3AKA-A nrPDB Length = 166 Score = 32.3 bits (72), Expect = 0.77, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 33/98 (33%), Gaps = 16/98 (16%) Query: 585 DSDGSGKLGLKEF-----YILWTKIQKYQKIYREI--------DVDRSGTMNSYEMRKAL 631 D DG ++ +EF L K ++ +I R D D G + + +AL Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARAL 124 Query: 632 EEAGFKMPCQL-HQVIVARFADDQLIIDFDNFVRCLVR 668 G +P L Q A D + V R Sbjct: 125 TAFG--VPEDLARQAAAALDTDGDGKVGETEIVPAFAR 160 >4MEW-A nrPDB Length = 356 Score = 32.3 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 22/106 (20%) Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMR------------KALEEAGFK-MPCQ 641 +E T I+ + +R +D+D G ++ +E+ A+E F+ CQ Sbjct: 257 EEDKKTPTSIEYW---FRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQ 313 Query: 642 LHQVIVARFADDQLIIDFDNFVRC---LVRLETLFKIFKQLDPENT 684 + ++ R + I + RC V +T F I K LD E Sbjct: 314 MLDLVKPR---TEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQK 356 >2NA0-A nrPDB Length = 205 Score = 31.9 bits (71), Expect = 0.88, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 42/120 (35%), Gaps = 16/120 (13%) Query: 577 CKIMVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKA 630 + M + D + G + E+ + + QK + ++ DVD +G ++ E+ Sbjct: 56 VEQMFETFDFNKDGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTI 115 Query: 631 LEEAGFKMPCQLHQVIVARFAD---------DQLIIDFDNFVRCLVRLETLFKIF-KQLD 680 + PC + F D + + F+ + + + L + LD Sbjct: 116 IRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLD 175 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 24/52 (46%) Query: 548 ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYI 599 I EL TI+R + A S + E + +D +G G+L L+EF Sbjct: 107 IDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFME 158 >3HB6-A nrPDB Length = 484 Score = 31.9 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 19/92 (20%) Query: 488 TFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDI-------------DDGF 534 T+EPN G F +++ D++ IE + ++ ED+ DD Sbjct: 381 TYEPNSGGVF------QEQPDFKEPPLSIEGAADHWNHREDEDYFSQPRALYELLSDDEH 434 Query: 535 RRLFAQLAGEDAEISAFELQTILRRVLAKRQD 566 +R+FA++AGE ++ S Q + + Sbjct: 435 QRMFARIAGELSQASKETQQRQIDLFTKVHPE 466 >1A75-A nrPDB Length = 108 Score = 31.5 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 25/64 (39%), Gaps = 4/64 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLIIDFDN 661 +K + ID D+SG + E++ + + + + + A +D I + Sbjct: 42 DIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGDGAIGVEE 101 Query: 662 FVRC 665 +V Sbjct: 102 WVAL 105 >4RI0-A nrPDB Length = 332 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 2 AGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQ----DPSFPAIPSA 57 AGI+ + DR D+ IK + + +R + + + +P FP + S Sbjct: 197 AGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSG 256 Query: 58 LGFKELGPYSSKTRG 72 + +E+ P S RG Sbjct: 257 IYVQEVAPNSPSQRG 271 >4PAL-A nrPDB Length = 108 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 24/67 (35%), Gaps = 4/67 (5%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKMPC-QLHQVIVARFADDQLII 657 + +K + ID D+SG + E++ + + + + + D +I Sbjct: 38 KSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMI 97 Query: 658 DFDNFVR 664 D F Sbjct: 98 GVDEFAA 104 >4NQG-A nrPDB Length = 197 Score = 31.1 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 580 MVDMLDSDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + D++D DG+G + L E+ + + + + D+D G ++ EM + Sbjct: 119 LFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 >2MBX-A nrPDB Length = 109 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEE--AGFK-MPC-QLHQVIVARFADDQLIIDFDN 661 +K++ ID D+S + E++ L+ AG + + + + A +D I D Sbjct: 43 DIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGKIGVDE 102 Query: 662 F 662 F Sbjct: 103 F 103 >1M39-A nrPDB Length = 89 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 14 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMIDE 65 Query: 584 LDSDGSGKLGLKEFYILWTK 603 D DG G++ +EF + K Sbjct: 66 ADRDGDGEVSEQEFLRIMKK 85 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 27/93 (29%), Gaps = 31/93 (33%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 E + D D +GK+ K +++ +E Sbjct: 21 EEILKAFKLFDDDETGKISFK------------------------------NLKRVAKEL 50 Query: 635 GFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 G + +L ++I D + F+R + Sbjct: 51 GENLTDEELQEMIDEADRDGDGEVSEQEFLRIM 83 >3AQL-A nrPDB Length = 415 Score = 31.1 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 450 KNFFLTNRARERS--DTFINLREVLNRFKLPP---GEYILVPSTFEPNKDGDFCIRVFSE 504 K+F +T A F N R V RF+L G I+ +TF + +G+ R S+ Sbjct: 52 KDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQ 111 Query: 505 KKADYQAVDDEIEANLEE 522 + + + D I ++EE Sbjct: 112 RGQNGMLLRDNIFGSIEE 129 >1BU3-A nrPDB Length = 109 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALE--EAGFK--MPCQLHQVIVARFADDQLIIDFDN 661 +K + ID D+SG + E++ L+ AG + + + A +D I D Sbjct: 43 DIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDE 102 Query: 662 FVRC 665 + Sbjct: 103 WAAL 106 >1YX7-A nrPDB Length = 83 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 527 EDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDS 586 + +++ F++L A D ++A ELQT + L + + D E ++ M D Sbjct: 6 KAELEAAFKKL---DANGDGYVTALELQTFMVT-LDAYKALSKDKVK-EASAKLIKMADK 60 Query: 587 DGSGKLGLKEF 597 + GK+ +EF Sbjct: 61 NSDGKISKEEF 71 >4I5K-A nrPDB Length = 285 Score = 30.8 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 42/105 (40%), Gaps = 22/105 (20%) Query: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMR-------KALEEAGFK------MPCQ 641 +E T I+ + +R +DVD G ++ YE+ + +E G + + CQ Sbjct: 183 EEDKRNPTSIEYW---FRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQ 239 Query: 642 LHQVIVARFADDQLIIDFDNFVRCL---VRLETLFKIFKQLDPEN 683 + ++ I + RC + +T F + K LD E Sbjct: 240 MLDLVKPAV---DGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQ 281 >2K2I-A nrPDB Length = 79 Score = 30.8 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 525 ISEDDIDDGFRRLFAQLAGED-AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDM 583 +SE D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 4 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMIDE 55 Query: 584 LDSDGSGKLGLKEFYILWTK 603 D DG G++ +EF + K Sbjct: 56 ADRDGDGEVSEQEFLRIMKK 75 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 27/93 (29%), Gaps = 31/93 (33%) Query: 575 ETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 E + D D +GK+ K +++ +E Sbjct: 11 EEILKAFKLFDDDETGKISFK------------------------------NLKRVAKEL 40 Query: 635 GFKMP-CQLHQVIVARFADDQLIIDFDNFVRCL 666 G + +L ++I D + F+R + Sbjct: 41 GENLTDEELQEMIDEADRDGDGEVSEQEFLRIM 73 >2NCO-A nrPDB Length = 102 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 16/25 (64%) Query: 668 RLETLFKIFKQLDPENTGTIELDLI 692 +L+ ++FK+ D + +G ++ D I Sbjct: 13 KLDVARRLFKRYDKDGSGQLQDDEI 37 >6EAZ-A nrPDB Length = 379 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 47/230 (20%), Positives = 78/230 (33%), Gaps = 52/230 (22%) Query: 480 GEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRL-- 537 GEY + P DF V E ++E +++ DI+D + Sbjct: 44 GEYYMTPR--------DFLFSVMFE----------QVERKTLVKKLAKKDIEDVLSGIQT 85 Query: 538 ------FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGK 591 F + G+ IS E +L + GF + MLD DG+ Sbjct: 86 ARCGSTFFRDLGDKGVISYTEYLFLLTILTKPH-----SGFHVA-----FKMLDVDGNEM 135 Query: 592 LGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFA 651 + KEF L I K Q ++ + + + + ++E G Q+ RF Sbjct: 136 IERKEFVKLQKIISK-QDGFKTVKTNETEYQDPT-----VKEPGVNTTLQV------RFF 183 Query: 652 DDQLI--IDFDNFVRCLVRLETLFK--IFKQLDPENTGTIELDLISWLCF 697 + + + F R + L+T + F Q + D WL F Sbjct: 184 GKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLF 233 >2Y5I-A nrPDB Length = 99 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 543 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 602 G+ ++S EL+ +L L + D +E +++ LDS+ ++ EF +L Sbjct: 24 GDKYKLSKGELKELLNAELTDFLMSQKDPMLVE---KIMNDLDSNKDNEVDFNEFVVLVA 80 Query: 603 KIQ 605 + Sbjct: 81 ALT 83 >2MA2-A nrPDB Length = 81 Score = 30.0 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 574 IETCKIMVDM----LDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEM 627 +E + MV+ D DG G + +EF I+ Y + ++D ++ G ++ EM Sbjct: 8 VEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNF-PYLSAFGDLDQNQDGCISREEM 64 >6AGI-A nrPDB Length = 382 Score = 30.0 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 43/224 (19%), Positives = 83/224 (37%), Gaps = 47/224 (20%) Query: 442 GQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRV 501 G T+I ++ L +RER E + + P ++IL +T EP Sbjct: 1 GSTDI---EDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEP---------- 47 Query: 502 FSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVL 561 + ++++ + L + + G +LF L E IS E +L + Sbjct: 48 --KVAKTWKSLSKQ---ELNQMLAETPPVWKGSSKLFRNLK-EKGVISYTEYLFLLCILT 101 Query: 562 AKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGT 621 GF +I +M D+DG+ + KEF +L Q+I+R+ + R Sbjct: 102 KPHA-----GF-----RIAFNMFDTDGNEMVDKKEFLVL-------QEIFRKKNEKRE-- 142 Query: 622 MNSYEMRKALEEA---GFK------MPCQLHQVIVARFADDQLI 656 + E ++A+ G+ + +++ + D Sbjct: 143 IKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRR 186 Score = 29.2 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 30/97 (30%), Gaps = 1/97 (1%) Query: 580 MVDMLDSDGSGKLGLKEFYILWTKIQ-KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKM 638 +V G +L ++FY +Q + +I + T++ + L Sbjct: 213 LVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVE 272 Query: 639 PCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKI 675 + V ++ I FD F L L Sbjct: 273 NTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDF 309 >2M7L-A nrPDB Length = 144 Score = 29.6 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 27/69 (39%), Gaps = 6/69 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF------KMPCQLHQVIVARFADDQLII 657 +Q++++ + D + G ++ E R L G + I + + Sbjct: 11 MQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVTKGENGV 70 Query: 658 DFDNFVRCL 666 FDN+V+ + Sbjct: 71 SFDNYVQYM 79 >5NRK-B nrPDB Length = 68 Score = 29.6 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 585 DSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQ 644 D DG+G + + +F ++ + K + D ++G +N K++ F + Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGD---KSINSLDFAIMRMYLL 60 Query: 645 VIVARFA 651 ++ +F+ Sbjct: 61 GMITKFS 67 >5JXU-A nrPDB Length = 397 Score = 29.6 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 48 DPSFPAIPSALGFK-ELGPYSSKTRGIEWKRPTEICADPQFIIG 90 +P +PS L F GP K G+E +RP + P F + Sbjct: 103 EPDLAPLPSRLTFTFGFGPGLFKAAGLEKQRPEGLRPLPPFKVD 146 >6ED3-A nrPDB Length = 848 Score = 29.6 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 192 YEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSL 237 YEA GG TE + + E++K P++F ++ + L +G L Sbjct: 658 YEA--GGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRL 701 >5LCW-N nrPDB Length = 822 Score = 29.2 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 39/105 (37%), Gaps = 11/105 (10%) Query: 478 PPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDE-----------IEANLEEFDIS 526 PPG + ++ ++D I E + + D+ I+A L + Sbjct: 709 PPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESL 768 Query: 527 EDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG 571 D R+F AEI ELQ L++ + +Q + S G Sbjct: 769 SLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSAG 813 >4PCW-A nrPDB Length = 94 Score = 29.2 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 27/65 (41%) Query: 536 RLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLK 595 LF Q + +D + + + + + I + + + +D LD D + K+ Sbjct: 15 NLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDHLDIDHNKKIDFT 74 Query: 596 EFYIL 600 EF ++ Sbjct: 75 EFLLM 79 >5CSF-A nrPDB Length = 95 Score = 29.2 bits (64), Expect = 6.2, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 537 LFAQLAGEDAE---ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLG 593 +F Q +G + + + EL+ ++ L+ + + E +++ LD+DG G+ Sbjct: 17 VFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQ---EVVDKVMETLDNDGDGECD 73 Query: 594 LKEF 597 +EF Sbjct: 74 FQEF 77 >2M1U-A nrPDB Length = 93 Score = 28.8 bits (63), Expect = 9.2, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 26/63 (41%), Gaps = 2/63 (3%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGFKMPC-QLHQVIVARFADDQLIIDFDNFVRCLV 667 + + D D G ++ E R + + G M ++ + A ++ ID+ F L Sbjct: 30 EAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADPNNTGFIDYKAFAAMLY 88 Query: 668 RLE 670 ++ Sbjct: 89 SVD 91 >1BOD-A nrPDB Length = 74 Score = 28.4 bits (62), Expect = 9.5, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 18/32 (56%) Query: 573 SIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 604 + T + + LD +G G++ +EF +L KI Sbjct: 41 GMSTLDELFEELDKNGDGEVSFEEFQVLVKKI 72 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.138 0.412 Lambda K H 0.267 0.0429 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,055,940 Number of Sequences: 36641 Number of extensions: 1416159 Number of successful extensions: 5232 Number of sequences better than 10.0: 259 Number of HSP's better than 10.0 without gapping: 200 Number of HSP's successfully gapped in prelim test: 143 Number of HSP's that attempted gapping in prelim test: 4034 Number of HSP's gapped (non-prelim): 825 length of query: 700 length of database: 10,336,785 effective HSP length: 104 effective length of query: 596 effective length of database: 6,526,121 effective search space: 3889568116 effective search space used: 3889568116 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 63 (28.8 bits)