BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P17540 (419 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4Z9M-A nrPDB 815 0.0 1CRK-A nrPDB 733 0.0 1QK1-A nrPDB 659 0.0 1U6R-A nrPDB 514 e-146 4Q2R-A nrPDB 512 e-146 1QH4-A nrPDB 503 e-143 1VRP-A nrPDB 496 e-141 3JU6-A nrPDB 432 e-121 3L2D-A nrPDB 427 e-120 3JPZ-A nrPDB 421 e-118 4RF9-A nrPDB 288 3e-78 2J1Q-A nrPDB 252 2e-67 4BG4-B nrPDB 251 5e-67 5ZHQ-A nrPDB 249 1e-66 5U8E-A nrPDB 244 3e-65 4GVZ-A nrPDB 241 5e-64 4WO8-A nrPDB 239 1e-63 6FH2-A nrPDB 91 8e-19 2I6E-A nrPDB 33 0.30 5IT7-II nrPDB 30 2.6 1UFA-A nrPDB 28 6.0 5C32-B nrPDB 28 7.7 >4Z9M-A nrPDB Length = 392 Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 27 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 86 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT Sbjct: 3 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 62 Query: 87 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 146 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD Sbjct: 63 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 122 Query: 147 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 206 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR Sbjct: 123 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 182 Query: 207 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 266 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE Sbjct: 183 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 242 Query: 267 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 326 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR Sbjct: 243 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 302 Query: 327 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 386 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI Sbjct: 303 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 362 Query: 387 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF 416 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF Sbjct: 363 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF 392 >1CRK-A nrPDB Length = 380 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/379 (89%), Positives = 366/379 (96%) Query: 41 VREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGH 100 V E+ +LFPPSADYPDLRKHNNCMAECLTPAIYAKLR+K+TPNGY+LDQCIQTGVDNPGH Sbjct: 2 VHEKRKLFPPSADYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGH 61 Query: 101 PFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYV 160 PFIKTVGMVAGDEESYEVFA++FDPVIK RHNGYDPR MKH TDLDASKIT GQFDE YV Sbjct: 62 PFIKTVGMVAGDEESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQFDERYV 121 Query: 161 LSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQR 220 LSSRVRTGRSIRGLSLPPAC+RAERREVENV +TAL GLKGDL+G+YY L+ M+E+DQQ+ Sbjct: 122 LSSRVRTGRSIRGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQQ 181 Query: 221 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNM 280 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHN DKTFL+WINEEDHTRVISMEKGGNM Sbjct: 182 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGNM 241 Query: 281 KRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDP 340 KRVFERFCRGLKEVERLI+ERGWEFMWNERLGY+LTCPSNLGTGLRAGVHV++P+LSKDP Sbjct: 242 KRVFERFCRGLKEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKDP 301 Query: 341 RFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKK 400 RF KILENLRLQKRGTGGVDTAAVADVYDISN+DR+GRSEVELVQIVIDGVNYLVDCEKK Sbjct: 302 RFPKILENLRLQKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEKK 361 Query: 401 LERGQDIKVPPPLPQFGKK 419 LE+GQDIKVPPPLPQFG+K Sbjct: 362 LEKGQDIKVPPPLPQFGRK 380 >1QK1-A nrPDB Length = 379 Score = 659 bits (1699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/371 (84%), Positives = 345/371 (92%) Query: 43 EQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPF 102 E+ RL+PPSA+YPDLRKHNNCMA LTPA+YA+L +K TP G+TLDQCIQTGVDNPGHPF Sbjct: 4 ERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPF 63 Query: 103 IKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLS 162 IKTVGMVAGDEE+YEVFADLFDPVI+ RHNGYDPR MKHTTDLDASKI G FDE YVLS Sbjct: 64 IKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLS 123 Query: 163 SRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLI 222 SRVRTGRSIRGLSLPPACTRAERREVE V + AL GLKGDLAGRYY+LSEMTE +QQ+LI Sbjct: 124 SRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLI 183 Query: 223 DDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKR 282 DDHFLFDKPVSPLLT AGMARDWPDARGIWHN +K+FLIW+NEEDHTRVISMEKGGNMKR Sbjct: 184 DDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKR 243 Query: 283 VFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRF 342 VFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVH+++P LSKD RF Sbjct: 244 VFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRF 303 Query: 343 SKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLE 402 KILENLRLQKRGTGGVDTAA V+DISN+DR+G+SEVELVQ+VIDGVNYL+DCE++LE Sbjct: 304 PKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLE 363 Query: 403 RGQDIKVPPPL 413 RGQDI++P P+ Sbjct: 364 RGQDIRIPTPV 374 >1U6R-A nrPDB Length = 380 Score = 514 bits (1325), Expect = e-146, Method: Compositional matrix adjust. Identities = 240/361 (66%), Positives = 286/361 (79%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 + +YPDL KHNN MA+ LTP +Y KLR+K TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEESY VF DLFDP+I+ RH G+ P KH TDL+ + G D HYVLSSRVR Sbjct: 73 CVAGDEESYTVFKDLFDPIIQDRHGGFKP-TDKHKTDLNHENLKGGDDLDPHYVLSSRVR 131 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TG+SI+G +LPP C+R ERR VE +++ AL L G+ G+YY L MTEQ+QQ+LIDDHF Sbjct: 132 TGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHF 191 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKPVSPLL +GMARDWPDARGIWHN +K+FL+W+NEEDH RVISMEKGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRR 251 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GL+++E + ++ G FMWNE LGY+LTCPSNLGTGLR GVHV++ LSK P+F +IL Sbjct: 252 FCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEIL 311 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 LRLQKRGTGGVDTAAV V+DISN DR+G SEVE VQ+V+DGV +V+ EKKLE+GQ Sbjct: 312 TRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQS 371 Query: 407 I 407 I Sbjct: 372 I 372 >4Q2R-A nrPDB Length = 381 Score = 512 bits (1319), Expect = e-146, Method: Compositional matrix adjust. Identities = 239/361 (66%), Positives = 288/361 (79%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 FP ++PDL HNN MA+ LTP +YA+LR K TP+G+T+D IQTGVDNPGHP+I TVG Sbjct: 14 FPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVG 73 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEESY+VF +LFDP+I+ RH GY P +H TDL+ + G D +YVLSSRVR Sbjct: 74 CVAGDEESYDVFKELFDPIIEDRHGGYKP-TDEHKTDLNPDNLQGGDDLDPNYVLSSRVR 132 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TGRSIRG LPP C+R ERR +E +A+ AL L GDLAGRYY L MTE +QQ+LIDDHF Sbjct: 133 TGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHF 192 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKPVSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L Sbjct: 253 FCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVL 312 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 + LRLQKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ E++LE+GQ Sbjct: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQA 372 Query: 407 I 407 I Sbjct: 373 I 373 >1QH4-A nrPDB Length = 380 Score = 503 bits (1295), Expect = e-143, Method: Compositional matrix adjust. Identities = 237/356 (66%), Positives = 284/356 (79%), Gaps = 2/356 (0%) Query: 53 DYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGD 112 +YPDL HNN MA+ LT +Y KLR++ T +G+TLD IQTGVDNPGHPFI TVG VAGD Sbjct: 18 EYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGD 77 Query: 113 EESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVRTGRSI 171 EESYEVF +LFDPVI+ RH GY P +H TDL+A + G D +YVLSSRVRTGRSI Sbjct: 78 EESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVRTGRSI 136 Query: 172 RGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKP 231 RG LPP C+R ERR +E +++ AL L GDL G+YY L MT+ +QQ+LIDDHFLFDKP Sbjct: 137 RGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKP 196 Query: 232 VSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGL 291 VSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF RFC GL Sbjct: 197 VSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGL 256 Query: 292 KEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRL 351 ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L+ LRL Sbjct: 257 TQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRL 316 Query: 352 QKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDI 407 QKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK+LE+GQ I Sbjct: 317 QKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSI 372 >1VRP-A nrPDB Length = 381 Score = 496 bits (1278), Expect = e-141, Method: Compositional matrix adjust. Identities = 236/361 (65%), Positives = 282/361 (78%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 + + ++PDL KHNN MA+ LT IY KLR+K TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 14 YSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTGVDNPGHPFIMTVG 73 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEE YEVF DLFDPVI+ RH GY P KH TDL+ + G D +YVLSSRVR Sbjct: 74 CVAGDEECYEVFKDLFDPVIEDRHGGYKP-TDKHKTDLNQENLKGGDDLDPNYVLSSRVR 132 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TGRSI+G++LPP C+R ERR VE + I L L G+ G+YY LS M++ +QQ+LIDDHF Sbjct: 133 TGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMSDAEQQQLIDDHF 192 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKP+SPLL +GMARDWPD RGIWHN DKTFL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISMQKGGNMKEVFRR 252 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GLK++E + + G FMWNE LGY+LTCPSNLGTGLR GVHV+IP L K +FS++L Sbjct: 253 FCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVL 312 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 + RLQKRGTGGVDTAAV +YDISN DR+G SEVE VQ+V+DGV +V+ EK+LE G+ Sbjct: 313 KRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKS 372 Query: 407 I 407 I Sbjct: 373 I 373 >3JU6-A nrPDB Length = 370 Score = 432 bits (1110), Expect = e-121, Method: Compositional matrix adjust. Identities = 208/361 (57%), Positives = 263/361 (72%), Gaps = 6/361 (1%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 +P D+P+ H + +++ LT +YAKLR+ TP+GYTLD+ IQ GVDNP +G Sbjct: 9 YPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNPDFH----LG 64 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRT 167 ++AGDEE+Y VFADLFDPVI+ HNG+ + H TDLDASKI D YV+SSRVRT Sbjct: 65 LLAGDEETYTVFADLFDPVIEEYHNGF-KKTDNHKTDLDASKILDDVLDPAYVISSRVRT 123 Query: 168 GRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFL 227 GR+IRG++L P R+ERR +E + AL L DL G+YY L +M E+ QQ+LIDDHFL Sbjct: 124 GRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQLIDDHFL 183 Query: 228 FDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERF 287 FD+PVS T GMARD+PD RGIWHN K FL+WINEEDHTR+ISM+ GGNMK VFERF Sbjct: 184 FDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNMKEVFERF 243 Query: 288 CRGLKEVERLIQER-GWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 RGL EVE+ I+++ G EFM N+ LG++LTCPSNLGTG+R VH ++P ++KD RF +I Sbjct: 244 TRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKDKRFEEIC 303 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 +RLQKRGT G T +V VYDISN+DR+G SEVE V VI GV L++ EKKLE+G+ Sbjct: 304 TKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEKKLEKGES 363 Query: 407 I 407 I Sbjct: 364 I 364 >3L2D-A nrPDB Length = 390 Score = 427 bits (1097), Expect = e-120, Method: Compositional matrix adjust. Identities = 209/361 (57%), Positives = 261/361 (72%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFI-KTV 106 F + ++PDL KHNN MA LT +Y K +KVTPNG T D+CIQTGVDNPG+ F K Sbjct: 25 FKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNGVTFDKCIQTGVDNPGNKFYGKKT 84 Query: 107 GMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVR 166 G V GDE SYE + + FD I+ H+ + P DLD +K+ G F++ YV S R+R Sbjct: 85 GCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAPDLDHNKLVGGVFEDKYVKSCRIR 143 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 GRS++G+ LPPA +RAERR VE V AL GLKGDLAG+YY L+ M E+DQ++LI+DHF Sbjct: 144 CGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDLAGKYYPLTTMNEKDQEQLIEDHF 203 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LF+KP LLT +G ARDWPD RGIWHN +K FL+WINEEDH RVISM+KGG++K VF R Sbjct: 204 LFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWINEEDHIRVISMQKGGDLKAVFSR 263 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 F RGL EVERL++E G M N+RLGYI TCP+N+GT +RA VH+R+ L K PRF ++L Sbjct: 264 FARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGTVVRASVHLRLAFLEKHPRFDEML 323 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 LRL KRGTGG + A YDISN R+G+SE ELVQ+++DGVN L+ C+KKLE GQ Sbjct: 324 GKLRLGKRGTGGESSLATDSTYDISNWARLGKSERELVQVLVDGVNLLIACDKKLEAGQS 383 Query: 407 I 407 I Sbjct: 384 I 384 >3JPZ-A nrPDB Length = 366 Score = 421 bits (1083), Expect = e-118, Method: Compositional matrix adjust. Identities = 205/356 (57%), Positives = 253/356 (71%), Gaps = 4/356 (1%) Query: 52 ADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAG 111 A++PD H + L +Y +L K T +G T+D+ IQ VDN F +G++AG Sbjct: 9 ANFPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDN----FGNCIGLIAG 64 Query: 112 DEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSI 171 DEESYEVF +LFD VI +H G+ P + DLDASK+ GQFDE YV S R+RTGR I Sbjct: 65 DEESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQFDEKYVKSCRIRTGRGI 124 Query: 172 RGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKP 231 RGL PP+CTR ERREVE V TAL GL GDL+G YY LS+MT + + +LI DHFLF KP Sbjct: 125 RGLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLFQKP 184 Query: 232 VSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGL 291 L+ + RDWPDARGIWHN +KTFLIWINEEDH RVISM+KGGN+K VFERF RGL Sbjct: 185 TGHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFGRGL 244 Query: 292 KEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRL 351 + +++ G E+MWN+RLGY+ CPSNLGTGLRA VHV++ +LSK P+F I+ L+L Sbjct: 245 NAIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVALQL 304 Query: 352 QKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDI 407 QKRGTGG TAAV DVYDISN R+ +SE E VQ++IDGV L+D E+ LE G+ I Sbjct: 305 QKRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSI 360 >4RF9-A nrPDB Length = 718 Score = 288 bits (738), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 154/363 (42%), Positives = 215/363 (59%), Gaps = 21/363 (5%) Query: 48 FPPSADYPDLRKHNNC-----MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPF 102 F +PD C + + LTP ++ L+NK T G TL CI +GV N Sbjct: 13 FKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCINSGVVN----L 68 Query: 103 IKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFD--EHYV 160 VG+ AGDEESY +F LFD +I+ H+ Y H +D++ + + D Y+ Sbjct: 69 DSGVGVYAGDEESYTLFGPLFDAIIEDYHSPY-KLATGHNSDMNPAHVKAPDLDPANRYI 127 Query: 161 LSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQR 220 S+R+R RS++G L P T+A R E+E + L L GDLAG+YY LS M E+ +Q+ Sbjct: 128 RSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVLTSLTGDLAGKYYPLSGMDEKTRQQ 187 Query: 221 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNM 280 L+DDHFLF K L AG+ ++WP+ RGI+HN DKTFL+W+NEEDH R+ISMEKG ++ Sbjct: 188 LVDDHFLFKKG-DRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHLRIISMEKGSDI 246 Query: 281 KRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDP 340 VF R CR + E+++ + F ++ GY+ +CPSNLGTG+RA VHV+IP + P Sbjct: 247 GSVFSRLCRAVNEIDKKLG-----FQHTKKHGYLTSCPSNLGTGMRASVHVKIPHAKEHP 301 Query: 341 RFSKILENLRLQKRGTGGVDTAAV---ADVYDISNIDRIGRSEVELVQIVIDGVNYLVDC 397 F IL +Q RG G + + A VYDISN R+G SEV+ VQ + DGV L++ Sbjct: 302 DFENILTKYHIQARGIHGEHSESTGEDAGVYDISNRRRLGLSEVQCVQDMYDGVKALMEL 361 Query: 398 EKK 400 EK+ Sbjct: 362 EKE 364 Score = 283 bits (723), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 150/364 (41%), Positives = 221/364 (60%), Gaps = 19/364 (5%) Query: 41 VREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGH 100 + ++ +FP P+++ + + + LTP ++ L++K T G +L CI +GV+N Sbjct: 366 IAKKRSVFPEVLKNPEVK---SLLRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN--- 419 Query: 101 PFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEH-- 158 + G+ AGDEE Y +FA LFD +++ H+ Y KHT+D++ K+ D Sbjct: 420 -LDSSCGVYAGDEECYTLFAPLFDKIVEDYHSPY-KLANKHTSDMNPEKVDAPNLDPEGT 477 Query: 159 YVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQ 218 Y+ S+R+R R+++G +L P TR ER ++E + L L GDLAG+YY L+ M E + Sbjct: 478 YIRSTRIRVARNVKGYALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEATR 537 Query: 219 QRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGG 278 Q+L++DHFLF K L AG+ + WP+ RGI+HN DKTFL+WINEED R+ISMEKG Sbjct: 538 QKLVNDHFLFKKG-DRFLEAAGVNKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKGS 596 Query: 279 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK 338 ++ VF R CR + E+++ + F + GY+ CP+NLGTG+RA VHV+IPK S Sbjct: 597 DIGSVFGRLCRAVNEIDKQLG-----FQHTDAHGYLSGCPTNLGTGMRASVHVKIPKASA 651 Query: 339 DPRFSKILENLRLQKRGTGG---VDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLV 395 P F KI + +Q RG G V T A V+DISN R+G SEV+ VQ + +GV L+ Sbjct: 652 HPDFQKICDEFHIQARGIHGEHSVSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKLL 711 Query: 396 DCEK 399 + EK Sbjct: 712 EIEK 715 >2J1Q-A nrPDB Length = 357 Score = 252 bits (643), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 139/353 (39%), Positives = 206/353 (58%), Gaps = 15/353 (4%) Query: 52 ADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGM 108 A + L+ ++C + + LT ++ +L+ K T G TL IQ+GV+N +G+ Sbjct: 12 AAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LDSGIGV 67 Query: 109 VAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEHYVLSSRVRT 167 A D ESY +FA L DP+I+ H G+ P + D D + D+ YV+S+RVR Sbjct: 68 YAPDAESYTLFAALLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVISTRVRC 127 Query: 168 GRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFL 227 GRS+ G P + + E+E+ LE + G+L G+YY L+ MT++ Q++LIDDHFL Sbjct: 128 GRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFL 187 Query: 228 FDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERF 287 F K L A + WP RGI+HN KTFL+W+NEEDH R+ISM+KGGN+K VF R Sbjct: 188 F-KEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRL 246 Query: 288 CRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKD-PRFSKIL 346 + +E ++ F ++RLG++ CP+NLGT +RA VH+++PKL D + ++ Sbjct: 247 VTAVGVIEEKVK-----FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLEEVA 301 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEK 399 LQ RGT G + + VYDISN R+G SE E V+ + DG+ L+ E+ Sbjct: 302 AKYNLQVRGTAGEHSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEE 354 >4BG4-B nrPDB Length = 356 Score = 251 bits (640), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 138/355 (38%), Positives = 209/355 (58%), Gaps = 15/355 (4%) Query: 52 ADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGM 108 A + L +C + + LT ++ KL++K T G TL IQ+GV+N VG+ Sbjct: 12 AGFKKLEAATDCRSLLKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN----LDSGVGI 67 Query: 109 VAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEHYVLSSRVRT 167 A D E+Y +FA LFDP+I+ H G+ D D + + +V+S+RVR Sbjct: 68 YAPDAEAYTLFAPLFDPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPEGKFVISTRVRC 127 Query: 168 GRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFL 227 GRS++G P T ++ +E+E + L L+G+L G YY L+ M+++ QQ+LIDDHFL Sbjct: 128 GRSMQGYPFNPCLTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHFL 187 Query: 228 FDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERF 287 F K L A R WP RGI+HN +KTFL+W+NEEDH R+ISM+ GG++ +VF R Sbjct: 188 F-KEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRL 246 Query: 288 CRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKD-PRFSKIL 346 + E+E+ I F ++RLG++ CP+NLGT +RA VH+++PKL+ + + ++ Sbjct: 247 TSAVNEIEKRIP-----FSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVA 301 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKL 401 LQ RGT G T A +YDISN R+G +E + V+ + DG+ L+ EK++ Sbjct: 302 GKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM 356 >5ZHQ-A nrPDB Length = 357 Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 137/354 (38%), Positives = 208/354 (58%), Gaps = 15/354 (4%) Query: 54 YPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVA 110 + L +C + + LT +++ +L+ K T G TL IQ+GV+N VG+ A Sbjct: 14 FKKLEAATDCKSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN----LDSGVGVYA 69 Query: 111 GDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEHYVLSSRVRTGR 169 D E+Y +FA LFDP+I+ H G+ D D ++ D +V+S+RVR GR Sbjct: 70 PDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGR 129 Query: 170 SIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFD 229 S+ G P T A+ +E+E+ + L L+G+L G YY L+ MT+ QQ+LIDDHFLF Sbjct: 130 SMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDDHFLF- 188 Query: 230 KPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCR 289 K L A R WP RGI+HN +KTFL+W +EEDH R+ISM+ GG++ +V+ R Sbjct: 189 KEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQMGGDLGQVYRRLVS 248 Query: 290 GLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKD-PRFSKILEN 348 + E+E+ + F ++RLG++ CP+NLGT +RA VH+++PKL+ + + ++ Sbjct: 249 AVNEIEKRV-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGK 303 Query: 349 LRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLE 402 LQ RGT G T A VYDISN R+G +E + V+ + DG+ L+ EK+++ Sbjct: 304 YSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ 357 >5U8E-A nrPDB Length = 384 Score = 244 bits (624), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 137/362 (37%), Positives = 204/362 (56%), Gaps = 15/362 (4%) Query: 43 EQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPG 99 +Q L A + L+ +C + + L ++ + ++ T G TL CIQ+GV+N Sbjct: 30 DQATLDKLEAGFKKLQDATDCKSLLKKYLNREVFDQCKSLKTALGATLLDCIQSGVEN-- 87 Query: 100 HPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEH 158 VG+ A D E+Y +FA +F+P+I+ H G+ P TD D + I Sbjct: 88 --LDSGVGIYAPDAEAYTLFAPIFNPIIEDYHEGFKPTDKHPPTDFGDINTIVNVDPSGK 145 Query: 159 YVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQ 218 YV+S+ VR GRS++G P T A +E+E+ +G+L G+YY L+ M + Q Sbjct: 146 YVVSTHVRCGRSLKGYPFNPCLTEANYKEMEDKVSAIFGTFEGELKGKYYPLTGMDKATQ 205 Query: 219 QRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGG 278 Q+LIDDHFLF K L A R WP RGI+HN KTFL+W+NEEDH R+ISM+KGG Sbjct: 206 QQLIDDHFLF-KEGDRFLQAANACRYWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGG 264 Query: 279 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK 338 ++K +F+R + +E + F ++RLG++ CP+NLGT +RA VH+ +PKL+K Sbjct: 265 DLKTIFQRLVNAVNTIESKL-----PFSRDDRLGFLTFCPTNLGTTIRASVHIALPKLAK 319 Query: 339 DPR-FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDC 397 D + I LQ RGT G T + VYDISN R+G +E + V+ + DG+ ++ Sbjct: 320 DKKQLEAIAAKFNLQVRGTRGEHTESEGGVYDISNKRRMGLTEYQAVKEMQDGILEMIKM 379 Query: 398 EK 399 E+ Sbjct: 380 EE 381 >4GVZ-A nrPDB Length = 357 Score = 241 bits (614), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 140/366 (38%), Positives = 207/366 (56%), Gaps = 23/366 (6%) Query: 43 EQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPG 99 +Q L A + L++ ++C + + LT ++ ++NK T G TL IQ+GV+N Sbjct: 3 DQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN-- 60 Query: 100 HPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGY---DPRVMKHTTDLDA--SKITQGQ 154 VG+ A D ESY F LFDP+I H G+ D K D++ GQ Sbjct: 61 --LDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQ 118 Query: 155 FDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMT 214 F ++S+RVR GRS++G P T + +E+E + L ++ +L G YY L+ M+ Sbjct: 119 F----IISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMS 174 Query: 215 EQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISM 274 + QQ+LIDDHFLF K L A R WP RGI+HN KTFL+W+NEEDH R+ISM Sbjct: 175 KATQQQLIDDHFLF-KEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISM 233 Query: 275 EKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIP 334 +KGG++K V++R + +E + F ++R G++ CP+NLGT +RA VH+++P Sbjct: 234 QKGGDLKTVYKRLVTAVDNIESKL-----PFSHDDRFGFLTFCPTNLGTTMRASVHIQLP 288 Query: 335 KLSKDPR-FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNY 393 KL+KD + I LQ RGT G T + VYDISN R+G +E + V+ + DG+ Sbjct: 289 KLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILE 348 Query: 394 LVDCEK 399 ++ EK Sbjct: 349 MIKMEK 354 >4WO8-A nrPDB Length = 716 Score = 239 bits (611), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 139/350 (39%), Positives = 197/350 (56%), Gaps = 15/350 (4%) Query: 56 DLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEES 115 D R H+ + LT I K + T G TL QC+ T NPG ++ D + Sbjct: 16 DERNHS-LTKKYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGALLPRSC-----DLNA 69 Query: 116 YEVFADLFDPVIKLRHNGYDPRVMKHTT---DLDASKITQGQFDEHYVLSSRVRTGRSIR 172 YE F D FD VI H D ++ + DL + T + V+S+RVR GR++ Sbjct: 70 YETFRDFFDAVIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVE 129 Query: 173 GLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPV 232 G P T+ R E+EN TAL L G+ G YY L+ M+E+D+ +L++DHFLF + Sbjct: 130 GFGFGPTLTKETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLF-RND 188 Query: 233 SPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLK 292 +L AG DWP RGI+ N K FL+WINEEDH RVISM+KGG + V++R ++ Sbjct: 189 DNVLRDAGGYIDWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQ 248 Query: 293 EVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQ 352 E+ + ++ F +N+RLG+I CPSNLGT LRA VH +IP L+ P F +I E +Q Sbjct: 249 ELSKSLK-----FAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQ 303 Query: 353 KRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLE 402 RGT G T +V +YD+SN R+G +E++ V + GV L++ E L+ Sbjct: 304 PRGTHGEHTESVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQ 353 Score = 236 bits (603), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 134/339 (39%), Positives = 197/339 (58%), Gaps = 17/339 (5%) Query: 68 LTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVI 127 LTP I K K T +G TL I+ G N +++ G+ E Y F D DP+I Sbjct: 390 LTPEIIKKYDGKRTTHGATLAHMIRNGAYNN-----RSICPRTGEAECYSTFIDYLDPLI 444 Query: 128 KLRHNGYDPRVMKHT--TDLDASKITQGQFDE--HYVLSSRVRTGRSIRGLSLPPACTRA 183 ++G KH T D SK+ G D +++S+RVR GRS+ G P ++ Sbjct: 445 -CDYHGVKDSAFKHPAPTFGDLSKLPFGDLDPTGKFIVSTRVRVGRSVEGFLFPTIMSKT 503 Query: 184 ERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMAR 243 +R ++E V AL+GL G+ AG YY L++M E+D+++L++DHFLF K P+L AG R Sbjct: 504 DRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDDPVLRDAGGYR 562 Query: 244 DWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGW 303 DWP RGI+HN KTFL+W+ EEDH R+ISM++GGN+ V++R G+ + + ++ Sbjct: 563 DWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINAIGKSMK---- 618 Query: 304 EFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDP-RFSKILENLRLQKRGTGGVDTA 362 F +++ GYI CPSNLGT +RA V ++IPKLS P + +I LQ RG G T Sbjct: 619 -FAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQARGLYGEHTE 677 Query: 363 AVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKL 401 + YDISN R+G +E++ + +GV +++ EK L Sbjct: 678 SPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 >6FH2-A nrPDB Length = 366 Score = 91.3 bits (225), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 122/245 (49%), Gaps = 21/245 (8%) Query: 160 VLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRY--YKLSEMTEQD 217 VLSSR+R R+I P + E +++ + A AGR+ K+SE+ + Sbjct: 28 VLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSELQPIE 87 Query: 218 QQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKG 277 ++ L++ H +SP L A D P + ++ I INEEDH R+ + G Sbjct: 88 KRVLVEKHL-----ISPHL-----AEDSPFGACLLSE-NEEISIMINEEDHIRIQCLFPG 136 Query: 278 GNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLS 337 + E E++ I E + ++ERLGY+ +CP+N+GTGLRA V + +P L Sbjct: 137 LQLAEALE----AASELDDWI-EGHVNYAFDERLGYLTSCPTNVGTGLRASVMMHLPALV 191 Query: 338 KDPRFSKI---LENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYL 394 + ++I + L L RGT G + A+ +++ ISN +G+SE ++V + V L Sbjct: 192 LTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHTIVEQL 251 Query: 395 VDCEK 399 + E+ Sbjct: 252 IAQER 256 >2I6E-A nrPDB Length = 301 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 19/96 (19%) Query: 236 LTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKG---------GNMKRVFER 286 +T +A++W D G + TF +W +D+ ++ + G++ V +R Sbjct: 185 ITVTDLAQEWFDLTG----HPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQR 240 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLG 322 L ER++Q ++WN R Y L P LG Sbjct: 241 HAEKLGLPERVVQH----YLWNFR--YHLEAPDRLG 270 >5IT7-II nrPDB Length = 216 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 178 PACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRL-IDDHFLFDKPVSPLL 236 P C E+E ++ ALE + A +Y +++MT +D L + H ++ +L Sbjct: 45 PLCVHLVSNELEQLSSEALEAAR-ITANKY--ITKMTGRDSFHLRVRVHPFHVLRINKML 101 Query: 237 TCAGMARDWPDARGIW 252 +CAG R RG W Sbjct: 102 SCAGADRLQQGMRGAW 117 >1UFA-A nrPDB Length = 520 Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 17/125 (13%) Query: 101 PFIKTVGMVA-GDEESYEVFADLFDPVI----KLRHNGYDPRVMKHTTDLDASKITQGQF 155 P+++ GM G+E YE A+ + P+I +LR G + T + A ++ + Sbjct: 13 PYVRAHGMWPFGEETLYEAMAETYLPLIRVLERLRAEGVEAPFTLGITPILAEQLADARI 72 Query: 156 DEHYVLSSRVRTGRS------IRGLSLPPACTRAERREVENVAIT--ALEGLKGDLAGRY 207 E + ++ R R+ RG +L + R +V +T + L GDL + Sbjct: 73 KEGFWAYAKDRLERAQGDYQRYRGTALEASA----RHQVAFWELTLDHFQRLSGDLVAAF 128 Query: 208 YKLSE 212 K E Sbjct: 129 RKAEE 133 >5C32-B nrPDB Length = 128 Score = 28.1 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 7/67 (10%) Query: 335 KLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYL 394 K+ + + K +EN + ++ V+ + D + + +IDR+GR+ E VI VNYL Sbjct: 29 KIFTEKQSGKSIENRPILQKALNFVE---MGDRFIVESIDRLGRNYNE----VIHTVNYL 81 Query: 395 VDCEKKL 401 D E +L Sbjct: 82 KDKEVQL 88 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4Z9M-A nrPDB 668 0.0 1CRK-A nrPDB 646 0.0 1QK1-A nrPDB 612 e-176 4Q2R-A nrPDB 599 e-172 1U6R-A nrPDB 593 e-170 1QH4-A nrPDB 592 e-169 1VRP-A nrPDB 588 e-168 3L2D-A nrPDB 553 e-158 3JPZ-A nrPDB 542 e-154 3JU6-A nrPDB 538 e-153 4BG4-B nrPDB 529 e-150 5ZHQ-A nrPDB 526 e-150 5U8E-A nrPDB 522 e-148 4GVZ-A nrPDB 511 e-145 2J1Q-A nrPDB 501 e-142 4RF9-A nrPDB 487 e-138 4WO8-A nrPDB 446 e-126 6FH2-A nrPDB 262 2e-70 Sequences not found previously or not previously below threshold: 6D1P-A nrPDB 34 0.16 3I44-A nrPDB 33 0.27 5B6K-A nrPDB 31 0.97 3U1H-A nrPDB 30 2.0 2XND-D nrPDB 30 2.2 2W6I-D nrPDB 30 2.2 3IO3-A nrPDB 29 3.3 1S6C-A nrPDB 28 6.2 1S1E-A nrPDB 28 6.7 CONVERGED! >4Z9M-A nrPDB Length = 392 Score = 668 bits (1723), Expect = 0.0, Method: Composition-based stats. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 27 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 86 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT Sbjct: 3 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 62 Query: 87 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 146 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD Sbjct: 63 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 122 Query: 147 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 206 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR Sbjct: 123 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 182 Query: 207 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 266 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE Sbjct: 183 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 242 Query: 267 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 326 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR Sbjct: 243 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 302 Query: 327 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 386 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI Sbjct: 303 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 362 Query: 387 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF 416 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF Sbjct: 363 VIDGVNYLVDCEKKLERGQDIKVPPPLPQF 392 >1CRK-A nrPDB Length = 380 Score = 646 bits (1667), Expect = 0.0, Method: Composition-based stats. Identities = 341/379 (89%), Positives = 366/379 (96%) Query: 41 VREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGH 100 V E+ +LFPPSADYPDLRKHNNCMAECLTPAIYAKLR+K+TPNGY+LDQCIQTGVDNPGH Sbjct: 2 VHEKRKLFPPSADYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGH 61 Query: 101 PFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYV 160 PFIKTVGMVAGDEESYEVFA++FDPVIK RHNGYDPR MKH TDLDASKIT GQFDE YV Sbjct: 62 PFIKTVGMVAGDEESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQFDERYV 121 Query: 161 LSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQR 220 LSSRVRTGRSIRGLSLPPAC+RAERREVENV +TAL GLKGDL+G+YY L+ M+E+DQQ+ Sbjct: 122 LSSRVRTGRSIRGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQQ 181 Query: 221 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNM 280 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHN DKTFL+WINEEDHTRVISMEKGGNM Sbjct: 182 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGNM 241 Query: 281 KRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDP 340 KRVFERFCRGLKEVERLI+ERGWEFMWNERLGY+LTCPSNLGTGLRAGVHV++P+LSKDP Sbjct: 242 KRVFERFCRGLKEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKDP 301 Query: 341 RFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKK 400 RF KILENLRLQKRGTGGVDTAAVADVYDISN+DR+GRSEVELVQIVIDGVNYLVDCEKK Sbjct: 302 RFPKILENLRLQKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEKK 361 Query: 401 LERGQDIKVPPPLPQFGKK 419 LE+GQDIKVPPPLPQFG+K Sbjct: 362 LEKGQDIKVPPPLPQFGRK 380 >1QK1-A nrPDB Length = 379 Score = 612 bits (1578), Expect = e-176, Method: Composition-based stats. Identities = 315/372 (84%), Positives = 345/372 (92%) Query: 42 REQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHP 101 E+ RL+PPSA+YPDLRKHNNCMA LTPA+YA+L +K TP G+TLDQCIQTGVDNPGHP Sbjct: 3 SERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHP 62 Query: 102 FIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVL 161 FIKTVGMVAGDEE+YEVFADLFDPVI+ RHNGYDPR MKHTTDLDASKI G FDE YVL Sbjct: 63 FIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVL 122 Query: 162 SSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRL 221 SSRVRTGRSIRGLSLPPACTRAERREVE V + AL GLKGDLAGRYY+LSEMTE +QQ+L Sbjct: 123 SSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQL 182 Query: 222 IDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMK 281 IDDHFLFDKPVSPLLT AGMARDWPDARGIWHN +K+FLIW+NEEDHTRVISMEKGGNMK Sbjct: 183 IDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMK 242 Query: 282 RVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPR 341 RVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVH+++P LSKD R Sbjct: 243 RVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSR 302 Query: 342 FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKL 401 F KILENLRLQKRGTGGVDTAA V+DISN+DR+G+SEVELVQ+VIDGVNYL+DCE++L Sbjct: 303 FPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRL 362 Query: 402 ERGQDIKVPPPL 413 ERGQDI++P P+ Sbjct: 363 ERGQDIRIPTPV 374 >4Q2R-A nrPDB Length = 381 Score = 599 bits (1544), Expect = e-172, Method: Composition-based stats. Identities = 239/361 (66%), Positives = 288/361 (79%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 FP ++PDL HNN MA+ LTP +YA+LR K TP+G+T+D IQTGVDNPGHP+I TVG Sbjct: 14 FPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVG 73 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEESY+VF +LFDP+I+ RH GY P +H TDL+ + G D +YVLSSRVR Sbjct: 74 CVAGDEESYDVFKELFDPIIEDRHGGYKP-TDEHKTDLNPDNLQGGDDLDPNYVLSSRVR 132 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TGRSIRG LPP C+R ERR +E +A+ AL L GDLAGRYY L MTE +QQ+LIDDHF Sbjct: 133 TGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHF 192 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKPVSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L Sbjct: 253 FCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVL 312 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 + LRLQKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ E++LE+GQ Sbjct: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQA 372 Query: 407 I 407 I Sbjct: 373 I 373 >1U6R-A nrPDB Length = 380 Score = 593 bits (1529), Expect = e-170, Method: Composition-based stats. Identities = 240/361 (66%), Positives = 286/361 (79%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 + +YPDL KHNN MA+ LTP +Y KLR+K TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEESY VF DLFDP+I+ RH G+ P KH TDL+ + G D HYVLSSRVR Sbjct: 73 CVAGDEESYTVFKDLFDPIIQDRHGGFKP-TDKHKTDLNHENLKGGDDLDPHYVLSSRVR 131 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TG+SI+G +LPP C+R ERR VE +++ AL L G+ G+YY L MTEQ+QQ+LIDDHF Sbjct: 132 TGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHF 191 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKPVSPLL +GMARDWPDARGIWHN +K+FL+W+NEEDH RVISMEKGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRR 251 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GL+++E + ++ G FMWNE LGY+LTCPSNLGTGLR GVHV++ LSK P+F +IL Sbjct: 252 FCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEIL 311 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 LRLQKRGTGGVDTAAV V+DISN DR+G SEVE VQ+V+DGV +V+ EKKLE+GQ Sbjct: 312 TRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQS 371 Query: 407 I 407 I Sbjct: 372 I 372 >1QH4-A nrPDB Length = 380 Score = 592 bits (1526), Expect = e-169, Method: Composition-based stats. Identities = 237/361 (65%), Positives = 285/361 (78%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 + +YPDL HNN MA+ LT +Y KLR++ T +G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEESYEVF +LFDPVI+ RH GY P +H TDL+A + G D +YVLSSRVR Sbjct: 73 CVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVR 131 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TGRSIRG LPP C+R ERR +E +++ AL L GDL G+YY L MT+ +QQ+LIDDHF Sbjct: 132 TGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHF 191 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKPVSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 251 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L Sbjct: 252 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 311 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 + LRLQKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK+LE+GQ Sbjct: 312 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQS 371 Query: 407 I 407 I Sbjct: 372 I 372 >1VRP-A nrPDB Length = 381 Score = 588 bits (1517), Expect = e-168, Method: Composition-based stats. Identities = 236/361 (65%), Positives = 282/361 (78%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 + + ++PDL KHNN MA+ LT IY KLR+K TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 14 YSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTGVDNPGHPFIMTVG 73 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 166 VAGDEE YEVF DLFDPVI+ RH GY P KH TDL+ + G D +YVLSSRVR Sbjct: 74 CVAGDEECYEVFKDLFDPVIEDRHGGYKP-TDKHKTDLNQENLKGGDDLDPNYVLSSRVR 132 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 TGRSI+G++LPP C+R ERR VE + I L L G+ G+YY LS M++ +QQ+LIDDHF Sbjct: 133 TGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMSDAEQQQLIDDHF 192 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LFDKP+SPLL +GMARDWPD RGIWHN DKTFL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISMQKGGNMKEVFRR 252 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 FC GLK++E + + G FMWNE LGY+LTCPSNLGTGLR GVHV+IP L K +FS++L Sbjct: 253 FCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVL 312 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 + RLQKRGTGGVDTAAV +YDISN DR+G SEVE VQ+V+DGV +V+ EK+LE G+ Sbjct: 313 KRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKS 372 Query: 407 I 407 I Sbjct: 373 I 373 >3L2D-A nrPDB Length = 390 Score = 553 bits (1426), Expect = e-158, Method: Composition-based stats. Identities = 209/361 (57%), Positives = 261/361 (72%), Gaps = 2/361 (0%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFI-KTV 106 F + ++PDL KHNN MA LT +Y K +KVTPNG T D+CIQTGVDNPG+ F K Sbjct: 25 FKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNGVTFDKCIQTGVDNPGNKFYGKKT 84 Query: 107 GMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVR 166 G V GDE SYE + + FD I+ H+ + P DLD +K+ G F++ YV S R+R Sbjct: 85 GCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAPDLDHNKLVGGVFEDKYVKSCRIR 143 Query: 167 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 226 GRS++G+ LPPA +RAERR VE V AL GLKGDLAG+YY L+ M E+DQ++LI+DHF Sbjct: 144 CGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDLAGKYYPLTTMNEKDQEQLIEDHF 203 Query: 227 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 286 LF+KP LLT +G ARDWPD RGIWHN +K FL+WINEEDH RVISM+KGG++K VF R Sbjct: 204 LFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWINEEDHIRVISMQKGGDLKAVFSR 263 Query: 287 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 F RGL EVERL++E G M N+RLGYI TCP+N+GT +RA VH+R+ L K PRF ++L Sbjct: 264 FARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGTVVRASVHLRLAFLEKHPRFDEML 323 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 LRL KRGTGG + A YDISN R+G+SE ELVQ+++DGVN L+ C+KKLE GQ Sbjct: 324 GKLRLGKRGTGGESSLATDSTYDISNWARLGKSERELVQVLVDGVNLLIACDKKLEAGQS 383 Query: 407 I 407 I Sbjct: 384 I 384 >3JPZ-A nrPDB Length = 366 Score = 542 bits (1396), Expect = e-154, Method: Composition-based stats. Identities = 205/358 (57%), Positives = 253/358 (70%), Gaps = 4/358 (1%) Query: 50 PSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMV 109 A++PD H + L +Y +L K T +G T+D+ IQ VDN F +G++ Sbjct: 7 AKANFPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDN----FGNCIGLI 62 Query: 110 AGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGR 169 AGDEESYEVF +LFD VI +H G+ P + DLDASK+ GQFDE YV S R+RTGR Sbjct: 63 AGDEESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQFDEKYVKSCRIRTGR 122 Query: 170 SIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFD 229 IRGL PP+CTR ERREVE V TAL GL GDL+G YY LS+MT + + +LI DHFLF Sbjct: 123 GIRGLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLFQ 182 Query: 230 KPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCR 289 KP L+ + RDWPDARGIWHN +KTFLIWINEEDH RVISM+KGGN+K VFERF R Sbjct: 183 KPTGHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFGR 242 Query: 290 GLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENL 349 GL + +++ G E+MWN+RLGY+ CPSNLGTGLRA VHV++ +LSK P+F I+ L Sbjct: 243 GLNAIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVAL 302 Query: 350 RLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDI 407 +LQKRGTGG TAAV DVYDISN R+ +SE E VQ++IDGV L+D E+ LE G+ I Sbjct: 303 QLQKRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSI 360 >3JU6-A nrPDB Length = 370 Score = 538 bits (1386), Expect = e-153, Method: Composition-based stats. Identities = 208/361 (57%), Positives = 261/361 (72%), Gaps = 6/361 (1%) Query: 48 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 107 +P D+P+ H + +++ LT +YAKLR+ TP+GYTLD+ IQ GVDNP G Sbjct: 9 YPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNPDFHL----G 64 Query: 108 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRT 167 ++AGDEE+Y VFADLFDPVI+ HNG+ H TDLDASKI D YV+SSRVRT Sbjct: 65 LLAGDEETYTVFADLFDPVIEEYHNGFKK-TDNHKTDLDASKILDDVLDPAYVISSRVRT 123 Query: 168 GRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFL 227 GR+IRG++L P R+ERR +E + AL L DL G+YY L +M E+ QQ+LIDDHFL Sbjct: 124 GRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQLIDDHFL 183 Query: 228 FDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERF 287 FD+PVS T GMARD+PD RGIWHN K FL+WINEEDHTR+ISM+ GGNMK VFERF Sbjct: 184 FDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNMKEVFERF 243 Query: 288 CRGLKEVERLIQER-GWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 346 RGL EVE+ I+++ G EFM N+ LG++LTCPSNLGTG+R VH ++P ++KD RF +I Sbjct: 244 TRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKDKRFEEIC 303 Query: 347 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 406 +RLQKRGT G T +V VYDISN+DR+G SEVE V VI GV L++ EKKLE+G+ Sbjct: 304 TKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEKKLEKGES 363 Query: 407 I 407 I Sbjct: 364 I 364 >4BG4-B nrPDB Length = 356 Score = 529 bits (1362), Expect = e-150, Method: Composition-based stats. Identities = 138/366 (37%), Positives = 212/366 (57%), Gaps = 15/366 (4%) Query: 41 VREQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDN 97 + + + A + L +C + + LT ++ KL++K T G TL IQ+GV+N Sbjct: 1 MADAAVIEKLEAGFKKLEAATDCRSLLKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN 60 Query: 98 PGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFD 156 VG+ A D E+Y +FA LFDP+I+ H G+ D D + + Sbjct: 61 ----LDSGVGIYAPDAEAYTLFAPLFDPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPE 116 Query: 157 EHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQ 216 +V+S+RVR GRS++G P T ++ +E+E + L L+G+L G YY L+ M+++ Sbjct: 117 GKFVISTRVRCGRSMQGYPFNPCLTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKE 176 Query: 217 DQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEK 276 QQ+LIDDHFLF K L A R WP RGI+HN +KTFL+W+NEEDH R+ISM+ Sbjct: 177 VQQKLIDDHFLF-KEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQM 235 Query: 277 GGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKL 336 GG++ +VF R + E+E+ I F ++RLG++ CP+NLGT +RA VH+++PKL Sbjct: 236 GGDLGQVFRRLTSAVNEIEKRI-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKL 290 Query: 337 SKD-PRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLV 395 + + + ++ LQ RGT G T A +YDISN R+G +E + V+ + DG+ L+ Sbjct: 291 AANREKLEEVAGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELI 350 Query: 396 DCEKKL 401 EK++ Sbjct: 351 KIEKEM 356 >5ZHQ-A nrPDB Length = 357 Score = 526 bits (1356), Expect = e-150, Method: Composition-based stats. Identities = 137/367 (37%), Positives = 211/367 (57%), Gaps = 15/367 (4%) Query: 41 VREQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDN 97 + + + + L +C + + LT +++ +L+ K T G TL IQ+GV+N Sbjct: 1 MADAATIAKLEEGFKKLEAATDCKSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN 60 Query: 98 PGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFD 156 VG+ A D E+Y +FA LFDP+I+ H G+ D D ++ D Sbjct: 61 ----LDSGVGVYAPDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPD 116 Query: 157 EHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQ 216 +V+S+RVR GRS+ G P T A+ +E+E+ + L L+G+L G YY L+ MT+ Sbjct: 117 GKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKD 176 Query: 217 DQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEK 276 QQ+LIDDHFLF K L A R WP RGI+HN +KTFL+W +EEDH R+ISM+ Sbjct: 177 VQQKLIDDHFLF-KEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQM 235 Query: 277 GGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKL 336 GG++ +V+ R + E+E+ + F ++RLG++ CP+NLGT +RA VH+++PKL Sbjct: 236 GGDLGQVYRRLVSAVNEIEKRV-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKL 290 Query: 337 SKD-PRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLV 395 + + + ++ LQ RGT G T A VYDISN R+G +E + V+ + DG+ L+ Sbjct: 291 AANREKLEEVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELI 350 Query: 396 DCEKKLE 402 EK+++ Sbjct: 351 KIEKEMQ 357 >5U8E-A nrPDB Length = 384 Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats. Identities = 137/367 (37%), Positives = 206/367 (56%), Gaps = 15/367 (4%) Query: 39 AEVREQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGV 95 + + +Q L A + L+ +C + + L ++ + ++ T G TL CIQ+GV Sbjct: 26 SHMVDQATLDKLEAGFKKLQDATDCKSLLKKYLNREVFDQCKSLKTALGATLLDCIQSGV 85 Query: 96 DNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQ 154 +N VG+ A D E+Y +FA +F+P+I+ H G+ P TD D + I Sbjct: 86 EN----LDSGVGIYAPDAEAYTLFAPIFNPIIEDYHEGFKPTDKHPPTDFGDINTIVNVD 141 Query: 155 FDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMT 214 YV+S+ VR GRS++G P T A +E+E+ +G+L G+YY L+ M Sbjct: 142 PSGKYVVSTHVRCGRSLKGYPFNPCLTEANYKEMEDKVSAIFGTFEGELKGKYYPLTGMD 201 Query: 215 EQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISM 274 + QQ+LIDDHFLF K L A R WP RGI+HN KTFL+W+NEEDH R+ISM Sbjct: 202 KATQQQLIDDHFLF-KEGDRFLQAANACRYWPTGRGIYHNDAKTFLVWVNEEDHLRIISM 260 Query: 275 EKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIP 334 +KGG++K +F+R + +E + F ++RLG++ CP+NLGT +RA VH+ +P Sbjct: 261 QKGGDLKTIFQRLVNAVNTIESKL-----PFSRDDRLGFLTFCPTNLGTTIRASVHIALP 315 Query: 335 KLSKDPR-FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNY 393 KL+KD + I LQ RGT G T + VYDISN R+G +E + V+ + DG+ Sbjct: 316 KLAKDKKQLEAIAAKFNLQVRGTRGEHTESEGGVYDISNKRRMGLTEYQAVKEMQDGILE 375 Query: 394 LVDCEKK 400 ++ E+ Sbjct: 376 MIKMEEA 382 >4GVZ-A nrPDB Length = 357 Score = 511 bits (1317), Expect = e-145, Method: Composition-based stats. Identities = 135/363 (37%), Positives = 203/363 (55%), Gaps = 15/363 (4%) Query: 43 EQPRLFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPG 99 +Q L A + L++ ++C + + LT ++ ++NK T G TL IQ+GV+N Sbjct: 3 DQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN-- 60 Query: 100 HPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEH 158 VG+ A D ESY F LFDP+I H G+ D + + Sbjct: 61 --LDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQ 118 Query: 159 YVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQ 218 +++S+RVR GRS++G P T + +E+E + L ++ +L G YY L+ M++ Q Sbjct: 119 FIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQ 178 Query: 219 QRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGG 278 Q+LIDDHFLF K L A R WP RGI+HN KTFL+W+NEEDH R+ISM+KGG Sbjct: 179 QQLIDDHFLF-KEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGG 237 Query: 279 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK 338 ++K V++R + +E + F ++R G++ CP+NLGT +RA VH+++PKL+K Sbjct: 238 DLKTVYKRLVTAVDNIESKL-----PFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAK 292 Query: 339 DPR-FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDC 397 D + I LQ RGT G T + VYDISN R+G +E + V+ + DG+ ++ Sbjct: 293 DRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKM 352 Query: 398 EKK 400 EK Sbjct: 353 EKA 355 >2J1Q-A nrPDB Length = 357 Score = 501 bits (1291), Expect = e-142, Method: Composition-based stats. Identities = 139/358 (38%), Positives = 207/358 (57%), Gaps = 15/358 (4%) Query: 47 LFPPSADYPDLRKHNNC---MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFI 103 + A + L+ ++C + + LT ++ +L+ K T G TL IQ+GV+N Sbjct: 7 VSKLEAAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LD 62 Query: 104 KTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDEHYVLS 162 +G+ A D ESY +FA L DP+I+ H G+ P + D D + D+ YV+S Sbjct: 63 SGIGVYAPDAESYTLFAALLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVIS 122 Query: 163 SRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLI 222 +RVR GRS+ G P + + E+E+ LE + G+L G+YY L+ MT++ Q++LI Sbjct: 123 TRVRCGRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLI 182 Query: 223 DDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKR 282 DDHFLF K L A + WP RGI+HN KTFL+W+NEEDH R+ISM+KGGN+K Sbjct: 183 DDHFLF-KEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKE 241 Query: 283 VFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKD-PR 341 VF R + +E ++ F ++RLG++ CP+NLGT +RA VH+++PKL D + Sbjct: 242 VFGRLVTAVGVIEEKVK-----FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKK 296 Query: 342 FSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEK 399 ++ LQ RGT G + + VYDISN R+G SE E V+ + DG+ L+ E+ Sbjct: 297 LEEVAAKYNLQVRGTAGEHSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEE 354 >4RF9-A nrPDB Length = 718 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 154/368 (41%), Positives = 215/368 (58%), Gaps = 21/368 (5%) Query: 43 EQPRLFPPSADYPDLRKHNNC-----MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDN 97 E F +PD C + + LTP ++ L+NK T G TL CI +GV N Sbjct: 8 ETAAKFKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCINSGVVN 67 Query: 98 PGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDE 157 VG+ AGDEESY +F LFD +I+ H+ Y H +D++ + + D Sbjct: 68 ----LDSGVGVYAGDEESYTLFGPLFDAIIEDYHSPYK-LATGHNSDMNPAHVKAPDLDP 122 Query: 158 --HYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTE 215 Y+ S+R+R RS++G L P T+A R E+E + L L GDLAG+YY LS M E Sbjct: 123 ANRYIRSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVLTSLTGDLAGKYYPLSGMDE 182 Query: 216 QDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISME 275 + +Q+L+DDHFLF K L AG+ ++WP+ RGI+HN DKTFL+W+NEEDH R+ISME Sbjct: 183 KTRQQLVDDHFLFKK-GDRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHLRIISME 241 Query: 276 KGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPK 335 KG ++ VF R CR + E+++ + F ++ GY+ +CPSNLGTG+RA VHV+IP Sbjct: 242 KGSDIGSVFSRLCRAVNEIDKKL-----GFQHTKKHGYLTSCPSNLGTGMRASVHVKIPH 296 Query: 336 LSKDPRFSKILENLRLQKRGTGGVDTAAVA---DVYDISNIDRIGRSEVELVQIVIDGVN 392 + P F IL +Q RG G + + VYDISN R+G SEV+ VQ + DGV Sbjct: 297 AKEHPDFENILTKYHIQARGIHGEHSESTGEDAGVYDISNRRRLGLSEVQCVQDMYDGVK 356 Query: 393 YLVDCEKK 400 L++ EK+ Sbjct: 357 ALMELEKE 364 Score = 447 bits (1150), Expect = e-126, Method: Composition-based stats. Identities = 146/364 (40%), Positives = 220/364 (60%), Gaps = 19/364 (5%) Query: 41 VREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGH 100 + ++ +FP P+++ + + + LTP ++ L++K T G +L CI +GV+N Sbjct: 366 IAKKRSVFPEVLKNPEVK---SLLRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN--- 419 Query: 101 PFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKI--TQGQFDEH 158 + G+ AGDEE Y +FA LFD +++ H+ Y KHT+D++ K+ + Sbjct: 420 -LDSSCGVYAGDEECYTLFAPLFDKIVEDYHSPYK-LANKHTSDMNPEKVDAPNLDPEGT 477 Query: 159 YVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQ 218 Y+ S+R+R R+++G +L P TR ER ++E + L L GDLAG+YY L+ M E + Sbjct: 478 YIRSTRIRVARNVKGYALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEATR 537 Query: 219 QRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGG 278 Q+L++DHFLF K L AG+ + WP+ RGI+HN DKTFL+WINEED R+ISMEKG Sbjct: 538 QKLVNDHFLFKK-GDRFLEAAGVNKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKGS 596 Query: 279 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK 338 ++ VF R CR + E+++ + F + GY+ CP+NLGTG+RA VHV+IPK S Sbjct: 597 DIGSVFGRLCRAVNEIDKQL-----GFQHTDAHGYLSGCPTNLGTGMRASVHVKIPKASA 651 Query: 339 DPRFSKILENLRLQKRGTGGVDTAAVA---DVYDISNIDRIGRSEVELVQIVIDGVNYLV 395 P F KI + +Q RG G + + V+DISN R+G SEV+ VQ + +GV L+ Sbjct: 652 HPDFQKICDEFHIQARGIHGEHSVSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKLL 711 Query: 396 DCEK 399 + EK Sbjct: 712 EIEK 715 >4WO8-A nrPDB Length = 716 Score = 446 bits (1147), Expect = e-126, Method: Composition-based stats. Identities = 139/351 (39%), Positives = 197/351 (56%), Gaps = 15/351 (4%) Query: 56 DLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEES 115 D R H+ + LT I K + T G TL QC+ T NPG ++ D + Sbjct: 16 DERNHS-LTKKYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGALLPRSC-----DLNA 69 Query: 116 YEVFADLFDPVIKLRHNGYDPRVMKHTT---DLDASKITQGQFDEHYVLSSRVRTGRSIR 172 YE F D FD VI H D ++ + DL + T + V+S+RVR GR++ Sbjct: 70 YETFRDFFDAVIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVE 129 Query: 173 GLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPV 232 G P T+ R E+EN TAL L G+ G YY L+ M+E+D+ +L++DHFLF + Sbjct: 130 GFGFGPTLTKETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLF-RND 188 Query: 233 SPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLK 292 +L AG DWP RGI+ N K FL+WINEEDH RVISM+KGG + V++R ++ Sbjct: 189 DNVLRDAGGYIDWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQ 248 Query: 293 EVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQ 352 E+ + ++ F +N+RLG+I CPSNLGT LRA VH +IP L+ P F +I E +Q Sbjct: 249 ELSKSLK-----FAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQ 303 Query: 353 KRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLER 403 RGT G T +V +YD+SN R+G +E++ V + GV L++ E L+ Sbjct: 304 PRGTHGEHTESVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQE 354 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 133/345 (38%), Positives = 193/345 (55%), Gaps = 15/345 (4%) Query: 61 NNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFA 120 + LTP I K K T +G TL I+ G N +T G+ E Y F Sbjct: 383 KCYTRKYLTPEIIKKYDGKRTTHGATLAHMIRNGAYNNRSICPRT-----GEAECYSTFI 437 Query: 121 DLFDPVIKLRHNGYDPRVMKHTTDL-DASKITQGQFDE--HYVLSSRVRTGRSIRGLSLP 177 D DP+I H D D SK+ G D +++S+RVR GRS+ G P Sbjct: 438 DYLDPLICDYHGVKDSAFKHPAPTFGDLSKLPFGDLDPTGKFIVSTRVRVGRSVEGFLFP 497 Query: 178 PACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLT 237 ++ +R ++E V AL+GL G+ AG YY L++M E+D+++L++DHFLF K P+L Sbjct: 498 TIMSKTDRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDDPVLR 556 Query: 238 CAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERL 297 AG RDWP RGI+HN KTFL+W+ EEDH R+ISM++GGN+ V++R G+ + + Sbjct: 557 DAGGYRDWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINAIGKS 616 Query: 298 IQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDP-RFSKILENLRLQKRGT 356 ++ F +++ GYI CPSNLGT +RA V ++IPKLS P + +I LQ RG Sbjct: 617 MK-----FAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQARGL 671 Query: 357 GGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKL 401 G T + YDISN R+G +E++ + +GV +++ EK L Sbjct: 672 YGEHTESPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 >6FH2-A nrPDB Length = 366 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 123/251 (49%), Gaps = 21/251 (8%) Query: 155 FDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRY--YKLSE 212 + VLSSR+R R+I P + E +++ + A AGR+ K+SE Sbjct: 23 PNSDIVLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSE 82 Query: 213 MTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVI 272 + +++ L++ H +SP L A D P + ++ I INEEDH R+ Sbjct: 83 LQPIEKRVLVEKHL-----ISPHL-----AEDSPFGACLLSENEE-ISIMINEEDHIRIQ 131 Query: 273 SMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVR 332 + G + E E++ I E + ++ERLGY+ +CP+N+GTGLRA V + Sbjct: 132 CLFPGLQLAEALE----AASELDDWI-EGHVNYAFDERLGYLTSCPTNVGTGLRASVMMH 186 Query: 333 IPKLSKDPRFSKI---LENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVID 389 +P L + ++I + L L RGT G + A+ +++ ISN +G+SE ++V + Sbjct: 187 LPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHT 246 Query: 390 GVNYLVDCEKK 400 V L+ E+ Sbjct: 247 IVEQLIAQERA 257 >6D1P-A nrPDB Length = 814 Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 36/101 (35%), Gaps = 8/101 (7%) Query: 291 LKEVERLIQERGWEFMWNERLGYILTCPSNL---GTGLRAGVHVRIPKLSKDPRFSKILE 347 L E+ +W+ + TC + L G LR H + + L Sbjct: 260 LTEISSYQISLKRPQLWSPHSPALYTCVAELIDNGDTLRTTQHFGFRHFRFEEKGPFYLN 319 Query: 348 NLRLQKRGTG-GVDTAAVADVYDISNIDRIGRSEVELVQIV 387 RL RGT D A V + + R+E++ ++ + Sbjct: 320 GERLLLRGTHRHEDHAGVGAAL----TEEMMRTEMQQIKEM 356 >3I44-A nrPDB Length = 497 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 44/134 (32%), Gaps = 31/134 (23%) Query: 9 LTGRNASLLFATMGTSVLTTGY---LLNRQKVCAE----VREQPRLFPPSADYPDLRKHN 61 L G+ A+++FA L G N + C + EQ D+ + Sbjct: 271 LGGKGANIIFADADIDALQRGVRHCFYNSGQSCNAPTRMLVEQAIYDKAIKTAKDIAEKT 330 Query: 62 ---------NCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGD 112 N + ++ Y K++ IQ+G+D G+ G Sbjct: 331 QVGPGHQTGNHIGPVVSKEQYDKIQ-----------DLIQSGIDEGATLVTGGTGLPMGM 379 Query: 113 EESY----EVFADL 122 E Y VFAD+ Sbjct: 380 ERGYYVRPTVFADV 393 >5B6K-A nrPDB Length = 366 Score = 31.1 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 339 DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCE 398 + +F ++ + K GTG D A+ V + +G ++L + + D ++ +++ E Sbjct: 304 NEQFPELKGKIPAGKPGTGNPD-DALTPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362 Query: 399 K 399 K Sbjct: 363 K 363 >3U1H-A nrPDB Length = 390 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 182 RAERREVENVAITALEG--LKGDLA---GRYYKLSEMTEQDQQRLIDD 224 E + +E L D+A G+Y +EMT++ + ++D+ Sbjct: 332 EEEAKAIEKAVEKVLAEGYRTADIAKPGGKYVSTTEMTDEVKAAVVDE 379 >2XND-D nrPDB Length = 467 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 31/80 (38%), Gaps = 12/80 (15%) Query: 339 DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCE 398 D IL L +Q R T V + +G S V + + DG LV + Sbjct: 18 DEGLPPILNALEVQGRETRLV----------LEVAQHLGESTVRTIAM--DGTEGLVRGQ 65 Query: 399 KKLERGQDIKVPPPLPQFGK 418 K L+ G I++P G+ Sbjct: 66 KVLDSGAPIRIPVGPETLGR 85 >2W6I-D nrPDB Length = 528 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 31/80 (38%), Gaps = 12/80 (15%) Query: 339 DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCE 398 D IL L +Q R T V + +G S V + + DG LV + Sbjct: 76 DEGLPPILNALEVQGRETRLV----------LEVAQHLGESTVRTIAM--DGTEGLVRGQ 123 Query: 399 KKLERGQDIKVPPPLPQFGK 418 K L+ G I++P G+ Sbjct: 124 KVLDSGAPIRIPVGPETLGR 143 >3IO3-A nrPDB Length = 348 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 271 VISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPS 319 ++SM GG + +FE+ L EV++ + E +F E +I C S Sbjct: 196 MLSMMGGGQQQDIFEK----LNEVQKNVSEVNEQFTNPELTTFICVCIS 240 >1S6C-A nrPDB Length = 183 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 6/57 (10%) Query: 341 RFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDC 397 +F + L + RGT ++YDI+ I + E ++D V + D Sbjct: 74 KFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEE------MMDIVKAIYDM 124 >1S1E-A nrPDB Length = 224 Score = 28.4 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 6/57 (10%) Query: 341 RFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDC 397 +F + L + RGT ++YDI+ I + E ++D V + D Sbjct: 107 KFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEE------MMDIVKAIYDM 157 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.140 0.391 Lambda K H 0.267 0.0429 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,372,696 Number of Sequences: 36641 Number of extensions: 745404 Number of successful extensions: 2100 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 1932 Number of HSP's gapped (non-prelim): 65 length of query: 419 length of database: 10,336,785 effective HSP length: 100 effective length of query: 319 effective length of database: 6,672,685 effective search space: 2128586515 effective search space used: 2128586515 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.0 bits)