BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P17256
(395 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
2R42-A nrPDB 798 0.0
2R3V-A nrPDB 639 0.0
4HAC-B nrPDB 118 5e-27
1KKH-A nrPDB 88 6e-18
2X7I-A nrPDB 59 4e-09
1WUU-A nrPDB 58 8e-09
2HFU-A nrPDB 56 2e-08
2AJ4-A nrPDB 39 0.006
2OI2-A nrPDB 39 0.006
3K85-A nrPDB 37 0.017
3V5R-A nrPDB 35 0.040
2A2C-A nrPDB 35 0.073
5XEA-A nrPDB 32 0.47
1PIE-A nrPDB 30 1.7
3VX8-B nrPDB 29 3.2
3K17-A nrPDB 29 3.4
4UT4-A nrPDB 28 5.8
2HKE-A nrPDB 28 9.7
>2R42-A nrPDB
Length = 395
Score = 798 bits (2062), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC
Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE
Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP
Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM
Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395
TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL
Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395
>2R3V-A nrPDB
Length = 396
Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 322/393 (81%), Positives = 355/393 (90%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC
Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E
Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP
Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM
Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393
T CGFDC ETSIGAPGVS+HSATS++ V+QAL
Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393
>4HAC-B nrPDB
Length = 321
Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 111/365 (30%), Positives = 164/365 (44%), Gaps = 81/365 (22%)
Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVW 62
S ++ SAPGK+ L GEHAVV+G+ A+A A+ LRT + + LN
Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRV--------RAELN---------- 60
Query: 63 DVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRK 122
D T+Q +G GL Y+ I +
Sbjct: 61 DSITIQ-------------------------------SQIGRTGLDFEKHPYVSAVIEKM 89
Query: 123 QRTLP--SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
++++P + + V S++P G+GLGSSAA ++ AL N L G
Sbjct: 90 RKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGAL--------NELFGFGL------- 134
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
L+ I K +E E + G S D VST+GG + + + + P I++ +T V
Sbjct: 135 SLQEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPERRK---LKTPDCGIVIGDTGVF 191
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
STK LVA VR +P+++ PL+TSI IS E+++ + Y + LM++
Sbjct: 192 SSTKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNV 244
Query: 301 NQHHLNALGVGHASLDQLC-QVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQA 359
NQ L+ALGV L QL AA +K+TGAGGGGC + L P K +A
Sbjct: 245 NQGLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP----EKCNQVAEA 300
Query: 360 LTGCG 364
+ G G
Sbjct: 301 VAGAG 305
>1KKH-A nrPDB
Length = 317
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 87/351 (24%), Positives = 142/351 (40%), Gaps = 77/351 (21%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65
+++ P KVIL GEHAVV+G A+++A++L + + ++ ++ LNL +
Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLND---------- 55
Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125
L K GL + + N ++ F +C + T
Sbjct: 56 -------------------------LNKSLGLNLNEIKN--INPNNFGDFKYCLCAIKNT 88
Query: 126 LPSLDI--------MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSW 177
L L+I + S++P GLGSSA+ ++ A + +
Sbjct: 89 LDYLNIEPKTGFKINISSKIPISCGLGSSASITIGTIKA-----------------VSGF 131
Query: 178 PEEDLKS--INKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235
++LK I K Y E+ I G S D S T+ G L + K +K + L
Sbjct: 132 YNKELKDDEIAKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIK--GEFEEFLK 189
Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPL--LTSIDAISLECERVLGEMAAAPVPEQYLV 293
N K L+ R K E++ + + + D I E ++V+ E E +
Sbjct: 190 NCKF------LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF-- 241
Query: 294 LEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLL 344
+LM N L L + LD++ + G +KLTGAGGGGC I L+
Sbjct: 242 -GKLMTKNHELLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291
>2X7I-A nrPDB
Length = 308
Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 87/340 (25%), Positives = 137/340 (40%), Gaps = 73/340 (21%)
Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVL-RPQSNGKVSLNLPNVGIKQVWDVAT-L 67
+ GK+IL GEHAV G+ A+AV N VL +G S +V ++D L
Sbjct: 11 STGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDHL 70
Query: 68 QLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLP 127
+ L F+E ++ P
Sbjct: 71 KSLVNRFVELNNITEP-------------------------------------------- 86
Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187
L + + + LPP GLGSSAA +V A + S +E+L
Sbjct: 87 -LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKAN 133
Query: 188 WAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPAL-QILLTNTKVPRSTKAL 246
WA E++ HG PSG+D G + +Q+G +LK L +++ +T V ST+
Sbjct: 134 WA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQA 190
Query: 247 VAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN 306
V V +L + P+ M+ + I + L V+ ++ L ++ + L
Sbjct: 191 VHDVH-KLCEDPQYMSH-VKHIGKLVLRASDVIEH-------HKFEALADIFNECHADLK 241
Query: 307 ALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLK 345
AL V H ++QL ++ +G + KLTGAG GG + L K
Sbjct: 242 ALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK 281
>1WUU-A nrPDB
Length = 399
Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 107/377 (28%), Positives = 152/377 (40%), Gaps = 86/377 (22%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65
L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + +
Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 95
Query: 66 TLQLLDTGFLEQGDVPAPTLEQ-LEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124
P PT ++ LE G PR +G+ + Y A
Sbjct: 96 -------------QFPLPTAQRSLEP-----GTPRWANYVKGV-----IQYYPAA----- 127
Query: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184
LP +V S +P G GL SSA+ V L C D G+I +
Sbjct: 128 PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR------- 173
Query: 185 INKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKM---------SSLKRL--PALQI 232
+ + E G P G+ D +S G Q+G +SL L P L +
Sbjct: 174 -AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAV 227
Query: 233 LLTNTKVPRSTKALVAGVRSRLIK----------FPEI-MAPLLTSIDAISLECER---- 277
L+TN+ V S + VR R + E+ + L + D +S E R
Sbjct: 228 LITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARH 287
Query: 278 VLGEM------AAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT-AAHGLH- 328
V+GE+ AAA Y LM + L + V LDQL + A G++
Sbjct: 288 VVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYG 347
Query: 329 SKLTGAGGGGCGITLLK 345
S++TG G GGC +TLL+
Sbjct: 348 SRMTGGGFGGCTVTLLE 364
>2HFU-A nrPDB
Length = 332
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 82/346 (23%), Positives = 135/346 (39%), Gaps = 70/346 (20%)
Query: 12 GKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLD 71
GKVIL GEH VVHG A+ ++ T L +++ +P LQ+ D
Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRL------EINPGVPG-----------LQVDD 62
Query: 72 TGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDI 131
G + EQ++ + V + + +GL +
Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQLVLDHLKVDLSGDGLKMF--------------------- 101
Query: 132 MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYE 191
+ L P +G+G+SA+ V + AL E L D + +N A+
Sbjct: 102 -IGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145
Query: 192 GERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQ----ILLTNTKVPRSTKALV 247
GE HG PSG DN+ +T+GG + Y++ S+ + A Q +++ T + ST +V
Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205
Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVL--GEMAAAPVPEQYLVLEELMDMNQHHL 305
V + P L + I + L G++ L +LM+ N
Sbjct: 206 NDVHKMKQQQPVQFKRLYDNYTHIVSQAREALQKGDLQR---------LGQLMNANHDLC 256
Query: 306 NALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLER 350
+ V L+ + Q +G L +KL+G G GG + L +R
Sbjct: 257 RQIDVSCRELESIVQTCRTYGALGAKLSGTGRGGIAVALAASSDQR 302
>2AJ4-A nrPDB
Length = 548
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Query: 315 LDQLCQVTAAHGLH-SKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
+D++C + ++G + S+LTGAG GGC + L+ PG +E K+AL
Sbjct: 468 IDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEAL 513
Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTA 160
L L + ++P G+GL SSAA+ VA A++ A
Sbjct: 171 LAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKA 205
>2OI2-A nrPDB
Length = 292
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 13/154 (8%)
Query: 193 ERVIHGNPSGVDNSVSTWGGALRYQQG-KMSSLKRLPALQILLTNTKVPRSTKALVAGVR 251
E + H NPSG+D +R+ + + L+ + +++ +T V T+ + V+
Sbjct: 124 EMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQ 183
Query: 252 SRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVG 311
++ + P L ++ ++ + E + + A L +++ HL +GV
Sbjct: 184 NK----GKDALPFLHALGELTQQAEIAISQKDAEG-------LGQILSQAHLHLKEIGVS 232
Query: 312 HASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLL 344
D L + +HG L +K++G G GGC I L+
Sbjct: 233 SLEADSLVETALSHGALGAKMSGGGLGGCIIALV 266
>3K85-A nrPDB
Length = 357
Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 16/105 (15%)
Query: 115 LYLAICRKQRTLP-SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGS 173
+Y I R R P S I +++ P G+GLG+S+ VC+ A + E ++ PL D
Sbjct: 84 VYNRIIRDYRLEPKSFKITTYNDAPAGSGLGTSSTMVVCILKAFI---EWLSLPLGDY-- 138
Query: 174 IGSWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQ 218
++ AYE ER G G + + G Y +
Sbjct: 139 ----------ETSRLAYEIERKDLGLSGGKQDQYAAAFGGFNYME 173
>3V5R-A nrPDB
Length = 505
Score = 35.4 bits (80), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 316 DQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
+Q+C + A+G S+LTGAG GGC I L+ P VE ++AL
Sbjct: 426 NQICSIALANGSFGSRLTGAGWGGCTIHLV-PSGANGNVEQVRKAL 470
>2A2C-A nrPDB
Length = 478
Score = 34.7 bits (78), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 300 MNQHHLNALGVGHAS---LDQLCQVTAAHGLH-SKLTGAGGGGCGITLL 344
MNQ H++ + S LDQL + G S+LTGAG GGC ++++
Sbjct: 384 MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMV 432
>5XEA-A nrPDB
Length = 466
Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 244 KALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYL-----VLEELM 298
+A A + SR + EI+ +++SI I ER++G + APV +++ +L + +
Sbjct: 300 RASFAELDSRFRQLSEILDTVISSIAKID---ERLIGRLIKAPVSSRFISEDKFLLHQCV 356
Query: 299 DMNQHHLNALG 309
D ++ N +G
Sbjct: 357 DSVANNTNCVG 367
>1PIE-A nrPDB
Length = 419
Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 4 EVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSL---NLPNVGI 58
EV +PG++ L GEH +G ++ + T + R + + KV L N P +G+
Sbjct: 47 EVEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKKVKLYSENFPKLGV 104
>3VX8-B nrPDB
Length = 292
Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 14/53 (26%), Positives = 27/53 (50%)
Query: 42 RPQSNGKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKV 94
+P+ GK NLP++ + + T+Q + T F + D P +E+ ++ V
Sbjct: 93 KPKDKGKEEDNLPSMDALDINEKNTIQSIPTYFGGEEDDDIPDMEEFDEADNV 145
>3K17-A nrPDB
Length = 365
Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 58/244 (23%), Positives = 91/244 (37%), Gaps = 52/244 (21%)
Query: 2 LSEVLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
L L V PGK+ + GE+AVV G A+ A+N ++ L + + + L +P+
Sbjct: 3 LKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVN--RYITLTLEDSERNELWIPHYENPV 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
W + G P E + + + +EG+ L
Sbjct: 61 SWPI-------------GGELKPDGEHWTFTAEAINIATTFLKSEGIEL----------- 96
Query: 121 RKQRTLPSLDIMVWSEL--PPGA--GLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGS 176
+ +++ +EL GA GLGSSAA +V V AL+T
Sbjct: 97 ------TPVKMVIETELIDQSGAKYGLGSSAAATVAVINALMTKF--------------- 135
Query: 177 WPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTN 236
+PE + K A V+ GN S D + +GG + Y +K A + L
Sbjct: 136 YPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWF 195
Query: 237 TKVP 240
K P
Sbjct: 196 MKEP 199
>4UT4-A nrPDB
Length = 346
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 16/86 (18%)
Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187
+L++ + + P G+GLGSS+ V + A + E + PL D +I +
Sbjct: 101 ALELSTFCDAPAGSGLGSSSTLVVVMIKAFV---ELLNLPLDD------------YAIAQ 145
Query: 188 WAYEGERVIHGNPSGVDNSVS-TWGG 212
AY ERV G G + S T+GG
Sbjct: 146 LAYRIERVDCGLAGGRQDQYSATFGG 171
>2HKE-A nrPDB
Length = 380
Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 118 AICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTN 166
+ C ++ ++I+ + P AG+ SSA+ ++AAL+ A + TN
Sbjct: 87 STCPEELKNKKVNIVSENNFPTAAGMASSASGYCAMSAALIRAFKSTTN 135
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
2R42-A nrPDB 535 e-152
2R3V-A nrPDB 501 e-142
4HAC-B nrPDB 257 4e-69
2HFU-A nrPDB 257 5e-69
1KKH-A nrPDB 256 9e-69
1WUU-A nrPDB 226 1e-59
2X7I-A nrPDB 222 2e-58
Sequences not found previously or not previously below threshold:
2DEI-A nrPDB 107 8e-24
1S4E-A nrPDB 102 2e-22
2OI2-A nrPDB 92 5e-19
2A2C-A nrPDB 86 2e-17
1PIE-A nrPDB 86 2e-17
2AJ4-A nrPDB 69 3e-12
3V5R-A nrPDB 66 2e-11
4N3O-A nrPDB 57 1e-08
3K17-A nrPDB 55 5e-08
3K85-A nrPDB 55 6e-08
5YYS-A nrPDB 54 1e-07
4UT4-A nrPDB 52 3e-07
4P52-A nrPDB 46 3e-05
3GON-A nrPDB 44 1e-04
4RPF-A nrPDB 35 0.042
3HUL-A nrPDB 34 0.12
3BEA-A nrPDB 32 0.66
4JA0-A nrPDB 31 0.99
4RBN-A nrPDB 30 1.6
5EKZ-A nrPDB 30 2.3
3UY5-A nrPDB 29 3.0
3F4A-A nrPDB 29 4.7
2YF3-A nrPDB 28 5.9
3FS5-A nrPDB 28 6.1
4HGV-A nrPDB 28 7.8
5I0M-A nrPDB 28 9.8
>2R42-A nrPDB
Length = 395
Score = 535 bits (1378), Expect = e-152, Method: Composition-based stats.
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC
Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE
Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP
Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM
Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395
TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL
Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395
>2R3V-A nrPDB
Length = 396
Score = 501 bits (1289), Expect = e-142, Method: Composition-based stats.
Identities = 322/393 (81%), Positives = 355/393 (90%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC
Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E
Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP
Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM
Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393
T CGFDC ETSIGAPGVS+HSATS++ V+QAL
Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393
>4HAC-B nrPDB
Length = 321
Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats.
Identities = 109/365 (29%), Positives = 163/365 (44%), Gaps = 81/365 (22%)
Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVW 62
S ++ SAPGK+ L GEHAVV+G+ A+A A+ LRT + ++
Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRVR------------------AELN 60
Query: 63 DVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRK 122
D T+Q +G GL Y+ I +
Sbjct: 61 DSITIQS-------------------------------QIGRTGLDFEKHPYVSAVIEKM 89
Query: 123 QRTLP--SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
++++P + + V S++P G+GLGSSAA ++ AL N L G
Sbjct: 90 RKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGAL--------NELFGFGL------- 134
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240
L+ I K +E E + G S D VST+GG + + + + P I++ +T V
Sbjct: 135 SLQEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPERRK---LKTPDCGIVIGDTGVF 191
Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300
STK LVA VR +P+++ PL+TSI IS E+++ + Y + LM++
Sbjct: 192 SSTKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNV 244
Query: 301 NQHHLNALGVGHASLDQLC-QVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQA 359
NQ L+ALGV L QL AA +K+TGAGGGGC + L P K +A
Sbjct: 245 NQGLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP----EKCNQVAEA 300
Query: 360 LTGCG 364
+ G G
Sbjct: 301 VAGAG 305
>2HFU-A nrPDB
Length = 332
Score = 257 bits (657), Expect = 5e-69, Method: Composition-based stats.
Identities = 81/347 (23%), Positives = 133/347 (38%), Gaps = 66/347 (19%)
Query: 12 GKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLD 71
GKVIL GEH VVHG A+ ++ T L +++ +P LQ+ D
Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRL------EINPGVPG-----------LQVDD 62
Query: 72 TGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDI 131
G + EQ++ + V + + +GL +
Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQLVLDHLKVDLSGDGLKMF--------------------- 101
Query: 132 MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYE 191
+ L P +G+G+SA+ V + AL E L D + +N A+
Sbjct: 102 -IGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145
Query: 192 GERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQ----ILLTNTKVPRSTKALV 247
GE HG PSG DN+ +T+GG + Y++ S+ + A Q +++ T + ST +V
Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205
Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307
V + P L + I + L L +LM+ N
Sbjct: 206 NDVHKMKQQQPVQFKRLYDNYTHIVSQAREAL-------QKGDLQRLGQLMNANHDLCRQ 258
Query: 308 LGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKV 353
+ V L+ + Q +G L +KL+G G GG + L +R +
Sbjct: 259 IDVSCRELESIVQTCRTYGALGAKLSGTGRGGIAVALAASSDQRDAI 305
>1KKH-A nrPDB
Length = 317
Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats.
Identities = 87/351 (24%), Positives = 142/351 (40%), Gaps = 77/351 (21%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65
+++ P KVIL GEHAVV+G A+++A++L + + ++ ++ LNL +
Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLND---------- 55
Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125
L K GL + + N ++ F +C + T
Sbjct: 56 -------------------------LNKSLGLNLNEIKN--INPNNFGDFKYCLCAIKNT 88
Query: 126 LPSLDI--------MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSW 177
L L+I + S++P GLGSSA+ ++ A + +
Sbjct: 89 LDYLNIEPKTGFKINISSKIPISCGLGSSASITIGTIKA-----------------VSGF 131
Query: 178 PEEDLK--SINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235
++LK I K Y E+ I G S D S T+ G L + K +K + L
Sbjct: 132 YNKELKDDEIAKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIK--GEFEEFLK 189
Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPL--LTSIDAISLECERVLGEMAAAPVPEQYLV 293
N K L+ R K E++ + + + D I E ++V+ E E +
Sbjct: 190 NCKF------LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF-- 241
Query: 294 LEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLL 344
+LM N L L + LD++ + G +KLTGAGGGGC I L+
Sbjct: 242 -GKLMTKNHELLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291
>1WUU-A nrPDB
Length = 399
Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats.
Identities = 105/393 (26%), Positives = 151/393 (38%), Gaps = 84/393 (21%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65
L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + +
Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 95
Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125
P PT ++ G PR +G+ + Y A
Sbjct: 96 -------------QFPLPTAQR----SLEPGTPRWANYVKGV-----IQYYPAA-----P 128
Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI 185
LP +V S +P G GL SSA+ V L C D G+I +
Sbjct: 129 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR-------- 173
Query: 186 NKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKM---------SSLKRL--PALQIL 233
+ + E G P G+ D +S G Q+G +SL L P L +L
Sbjct: 174 AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAVL 228
Query: 234 LTNTKVPRSTKALVAGVRSRLIKF-----------PEIMAPLLTSIDAISLECER----V 278
+TN+ V S + VR R + + L + D +S E R V
Sbjct: 229 ITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHV 288
Query: 279 LGEM------AAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT-AAHGL-HS 329
+GE+ AAA Y LM + L + V LDQL + A G+ S
Sbjct: 289 VGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGS 348
Query: 330 KLTGAGGGGCGITLLKPGLERAKVEAAKQALTG 362
++TG G GGC +TLL+ + ++ G
Sbjct: 349 RMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGG 381
>2X7I-A nrPDB
Length = 308
Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats.
Identities = 89/360 (24%), Positives = 142/360 (39%), Gaps = 76/360 (21%)
Query: 9 SAPGKVILHGEHAVVHGKVALAVALNLRTFLVL-RPQSNGKVSLNLPNVGIKQVWDVAT- 66
+ GK+IL GEHAV G+ A+AV N VL +G S +V ++D
Sbjct: 10 ESTGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDH 69
Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL 126
L+ L F+E ++ P
Sbjct: 70 LKSLVNRFVELNNITEP------------------------------------------- 86
Query: 127 PSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSIN 186
L + + + LPP GLGSSAA +V A + S +E+L
Sbjct: 87 --LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKA 132
Query: 187 KWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPAL-QILLTNTKVPRSTKA 245
WA E++ HG PSG+D G + +Q+G +LK L +++ +T V ST+
Sbjct: 133 NWA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQ 189
Query: 246 LVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHL 305
V V L + P+ M+ + I + L V+ ++ L ++ + L
Sbjct: 190 AVHDVHK-LCEDPQYMSHV-KHIGKLVLRASDVIEH-------HKFEALADIFNECHADL 240
Query: 306 NALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCG 364
AL V H ++QL ++ +G + KLTGAG GG + L K + + +A+ G
Sbjct: 241 KALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK---DLPTAKNIVKAVEKAG 297
>2DEI-A nrPDB
Length = 350
Score = 107 bits (267), Expect = 8e-24, Method: Composition-based stats.
Identities = 67/370 (18%), Positives = 116/370 (31%), Gaps = 79/370 (21%)
Query: 5 VLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDV 64
++ V +PG+V L GEH + +A+NL T + + +G+V L + G ++ + +
Sbjct: 1 MIKVKSPGRVNLIGEHTDYTYGYVMPMAINLYT--KIEAEKHGEVILYSEHFGEERKFSL 58
Query: 65 ATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124
L+ +G+ + +
Sbjct: 59 NDLRKE---------------------------NSWIDYVKGI--------FWVLKESDY 83
Query: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184
+ + V LP GAGL SSA++ V + L + L S
Sbjct: 84 EVGGIKGRVSGNLPLGAGLSSSASFEVGILETLDKLYNLKLDSL---------------S 128
Query: 185 INKWAYEGERVIHGNPSGV-DNSVSTWG--GALRYQQGKMSSLKRLP---ALQILLTNTK 238
A + E G P G+ D +G G + + + +P + IL+ T
Sbjct: 129 KVLLAKKAENEFVGVPCGILDQFAVVFGREGNVIFLDTHTLDYEYIPFPKDVSILVFYTG 188
Query: 239 VPRSTKALVAGVRS------------------RLIKFPEIMAPLLTSIDAISLECERVLG 280
V R + R R + ++ I E RVL
Sbjct: 189 VRRELASSEYAERKHIAEESLKILGKGSSKEVREGELSKLPPLHRKFFGYIVRENARVL- 247
Query: 281 EMAAAPVPEQYLVLEELMDMNQ-HHLNALGVGHASLDQLCQ-VTAAHGLHSKLTGAGGGG 338
E+ A + +++ V LD + ++LTGAG GG
Sbjct: 248 EVRDALKEGNVEEVGKILTTAHWDLAKNYEVSCKELDFFVERALKLGAYGARLTGAGFGG 307
Query: 339 CGITLLKPGL 348
I L+
Sbjct: 308 SAIALVDKED 317
>1S4E-A nrPDB
Length = 352
Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats.
Identities = 69/365 (18%), Positives = 107/365 (29%), Gaps = 79/365 (21%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65
+ V +PG+V L GEH + +A++L T +
Sbjct: 4 ITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTIITAEKYD-------------------- 43
Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125
+QL F E+ L + + EG
Sbjct: 44 KVQLYSEHFNEEKTFTLDNLTKEGSWIDYVKGVLWVLIQEGYK----------------- 86
Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI 185
+ L + +LP GAGL SSA++ V + L +PLK
Sbjct: 87 IGGLKGKITGDLPLGAGLSSSASFEVGILEVLNQLYNLNIDPLKKALLAK---------- 136
Query: 186 NKWAYEGERVIHGNPSGV-DNSVSTWGG-----ALRYQQGKMSSLKRLPALQILLTNTKV 239
+ E G P G+ D +G L Q + + + +L+ T V
Sbjct: 137 -----KAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTLQYEYIPFPKDVSVLVFYTGV 191
Query: 240 PRSTKALVAGVRSR----------LIKFPEIMAPLL--------TSIDAISLECERVLGE 281
R + R R E+ L I E RVL E
Sbjct: 192 KRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGKLPPLHRKFFSYIVRENARVL-E 250
Query: 282 MAAAPVPEQYLVLEELMDMNQ-HHLNALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGC 339
+ A + +++ V LD + G ++LTGAG GG
Sbjct: 251 VRDALKEGDIEKVGKILTTAHWDLAENYRVSCEELDFFVKKAMELGAYGARLTGAGFGGS 310
Query: 340 GITLL 344
I L+
Sbjct: 311 AIALV 315
>2OI2-A nrPDB
Length = 292
Score = 91.6 bits (225), Expect = 5e-19, Method: Composition-based stats.
Identities = 68/346 (19%), Positives = 125/346 (36%), Gaps = 82/346 (23%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
M +V + A K+IL GEHAVV+G A+++ L +V + V +
Sbjct: 1 MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPL-------------LEVEVTCKVVPAES 47
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
W + L + +Y ++
Sbjct: 48 PWRLYEEDTLS-----------------------------------------MAVYASLE 66
Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180
T + + S +P G+GSSAA S+ A+ L
Sbjct: 67 YLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDY---YQADLP----------H 113
Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQG-KMSSLKRLPALQILLTNTKV 239
D+ I E + H NPSG+D +R+ + + L+ + +++ +T V
Sbjct: 114 DVLEI--LVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGV 171
Query: 240 PRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMD 299
T+ + V+++ P L ++ ++ + E + + + L +++
Sbjct: 172 YGHTREAIQVVQNKGKD----ALPFLHALGELTQQAEIAISQ-------KDAEGLGQILS 220
Query: 300 MNQHHLNALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLL 344
HL +GV D L + +HG L +K++G G GGC I L+
Sbjct: 221 QAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALV 266
>2A2C-A nrPDB
Length = 478
Score = 86.2 bits (211), Expect = 2e-17, Method: Composition-based stats.
Identities = 66/384 (17%), Positives = 122/384 (31%), Gaps = 43/384 (11%)
Query: 8 VSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSL-NLPNVGIKQVWDVAT 66
V APG+V + GEH G L +A+ + + P + L N +
Sbjct: 58 VRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVKTYALQLANTNPLYPDFSTSANN 117
Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAI--CRKQR 124
+Q+ T L E +C+ + + + L A+ C
Sbjct: 118 IQIDKTKPLWHNYFLCGLKGIQEHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLV 177
Query: 125 TLPSLDIMVWSELPP--------------GAGLGSSAAYSVCVAAA-LLTACEEVTNPLK 169
TL L + S++ G G+ S ++ A L+ +K
Sbjct: 178 TLTVLGRNL-SKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVK 236
Query: 170 DRGSIGSWPEEDLKSINKWA------YEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSS 223
+NK A E + W LR ++ +
Sbjct: 237 LPSGAVFVIANSCVEMNKAATSHFNIRVMECRLAAK-LLAKYKSLQWDKVLRLEEVQAKL 295
Query: 224 LKRLPALQILLTNT---------KVPRSTKALVAGVRSRLIK---FPEIMAPLLTSIDAI 271
L + ++ + ++ R + +R++++ ++ L +
Sbjct: 296 GISLEEMLLVTEDALHPEPYNPEEICRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHV 355
Query: 272 SLECERVLG--EMAAAPVPEQYLVLEELMDMNQHHLNA-LGVGHASLDQLCQVTAAHGL- 327
E RVL ++ +L ELM+ + LDQL + G
Sbjct: 356 YSEAARVLQFKKICEEAPENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQ 415
Query: 328 HSKLTGAGGGGCGITLLKPGLERA 351
S+LTGAG GGC ++++ P +
Sbjct: 416 GSRLTGAGWGGCTVSMV-PADKLP 438
>1PIE-A nrPDB
Length = 419
Score = 86.2 bits (211), Expect = 2e-17, Method: Composition-based stats.
Identities = 71/394 (18%), Positives = 126/394 (31%), Gaps = 88/394 (22%)
Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQL 69
+PG++ L GEH +G ++ + T + R + + KV L N
Sbjct: 53 SPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKKVKLYSEN-------------- 98
Query: 70 LDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSL 129
F + G + E +K + +G+ ++ Y
Sbjct: 99 ----FPKLGVIEFDLDEVEKKDGE-----LWSNYVKGMIVMLKGAGYEIDK-------GF 142
Query: 130 DIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWA 189
++++ E+P +GL SSA+ + V L L + +
Sbjct: 143 ELLIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRL---------------ELVQLG 187
Query: 190 YEGERVIHGNPSGV-DNSVSTWGGALRYQQGKMSSLK------RLPALQILLTNTKVPRS 242
+ E G SG+ D +G + + ++LK L I++ NT PR+
Sbjct: 188 QKTENDYIGVNSGILDQFAIGFGEVKKAIELDCNTLKYEMVPVELRDYDIVIMNTNKPRA 247
Query: 243 TKALVAGVRSRLIKFPEIMAPLLTSID----------------------AISLECERVLG 280
R + E + + T +D + +
Sbjct: 248 LTESKYN--ERFAETREALKRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRARHAVY 305
Query: 281 E------MAAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT--AAHGLHSKL 331
E A V EL++ + L + V LD L + A L +++
Sbjct: 306 ENNRTKIAQKAFVAGNLTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGVLGARM 365
Query: 332 TGAGGGGCGITLLKP---GLERAKVEAAKQALTG 362
TGAG GGC I L+ R V + + G
Sbjct: 366 TGAGFGGCAIALVAHDNVSAFRKAVGQVYEEVVG 399
>2AJ4-A nrPDB
Length = 548
Score = 69.2 bits (167), Expect = 3e-12, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 249 GVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNAL 308
VR +++K + + S L+ +++ + + + LM+ +Q + L
Sbjct: 402 PVRFQVLKLYQRAKHVY-SESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKL 460
Query: 309 -GVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALT 361
+D++C + ++G S+LTGAG GGC + L+ PG +E K+AL
Sbjct: 461 YECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEALA 514
Score = 57.7 bits (137), Expect = 9e-09, Method: Composition-based stats.
Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 37/243 (15%)
Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQL 69
+PG+V L GEH L +A++ ++ + S+ L N K L
Sbjct: 70 SPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDL-- 127
Query: 70 LDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSL 129
L+ V GL + L+ F L L
Sbjct: 128 ----PLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERF---------ASAPLAGL 174
Query: 130 DIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWA 189
+ ++P G+GL SSAA+ VA A++ A ++G +++ +
Sbjct: 175 QVFCEGDVPTGSGLSSSAAFICAVALAVVKA------------NMGPGYHMSKQNLMRIT 222
Query: 190 YEGERVIHGNPSGVDNSVSTWGG-----ALRYQQGKMSSLKRLPALQ-----ILLTNTKV 239
E + N G+D + S G + ++ ++ + P L+ ++ NT V
Sbjct: 223 VVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLV 282
Query: 240 PRS 242
+
Sbjct: 283 VSN 285
>3V5R-A nrPDB
Length = 505
Score = 66.2 bits (159), Expect = 2e-11, Method: Composition-based stats.
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 249 GVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNAL 308
VR +++K + + S L+ +++ + + LM+ +Q + L
Sbjct: 359 PVRFQVLKLYQRAKHVY-SESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKL 417
Query: 309 -GVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
+Q+C + A+G S+LTGAG GGC I L+ P VE ++AL
Sbjct: 418 YECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLV-PSGANGNVEQVRKAL 470
Score = 58.5 bits (139), Expect = 5e-09, Method: Composition-based stats.
Identities = 41/250 (16%), Positives = 81/250 (32%), Gaps = 47/250 (18%)
Query: 7 LVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVAT 66
+ +PG+V L GEH L +A+++ ++ S+ L N K
Sbjct: 26 IARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFD 85
Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL 126
L L + V + +A YL +
Sbjct: 86 LPLDGSYMAIDPSVSE-----------------WSNYFKCGLHVAHSYLKKIAPERFNNT 128
Query: 127 PSLDIMV--WSELPPGAGLGS--SAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDL 182
P + + S++P G GL S + A ++ A ++G +
Sbjct: 129 PLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRA----------------NMGKNFDISK 172
Query: 183 KSINKWAYEGERVIHGNPSGVDNSVSTWGG-----ALRYQQGKMSSLKRLPALQ-----I 232
K + + E + N G+D + S +G + ++ ++ + P L+
Sbjct: 173 KDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISF 232
Query: 233 LLTNTKVPRS 242
++ NT V +
Sbjct: 233 VIANTLVKSN 242
>4N3O-A nrPDB
Length = 342
Score = 56.9 bits (135), Expect = 1e-08, Method: Composition-based stats.
Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 29/267 (10%)
Query: 102 VGNEG-LSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTA 160
+GN+G L + +Y + ++ L S + +S++P G+GLG S+ V V A
Sbjct: 75 LGNDGKLDIFKSIYNRIVKDFTKKPL-SFSLHTYSDVPSGSGLGGSSTLVVGVIKA---F 130
Query: 161 CEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQG 219
E + PL + I K AYE ER G G D +T+GG +
Sbjct: 131 AEWLNLPLGEY------------EIAKLAYEIEREDLGIVGGAQDQYAATFGGFNFMEFY 178
Query: 220 KMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSI-DAISLECERV 278
+ P + + N V + + +I + D SLE
Sbjct: 179 NNKRVIVNP---LRIKNWIASELEARTVLYFTNITREAKDIEEHKKGKLGDEKSLEAMHA 235
Query: 279 LGE----MAAAPVPEQYLVLEELMDMNQHHLNALG--VGHASLDQLCQVTAAHGLHS-KL 331
+ + M A + L +++ + + V + L+++ ++ +G +S K
Sbjct: 236 IKQDAIKMKEALFRADFGTLAQILGKSWRSKKIISEIVSNDELERIYKLAIDNGAYSGKT 295
Query: 332 TGAGGGGCGITLLKPGLERAKVEAAKQ 358
+GAG GG + P + ++A ++
Sbjct: 296 SGAGAGGFMFFFVDPTKKYNLIKALRK 322
>3K17-A nrPDB
Length = 365
Score = 55.4 bits (131), Expect = 5e-08, Method: Composition-based stats.
Identities = 71/329 (21%), Positives = 114/329 (34%), Gaps = 80/329 (24%)
Query: 2 LSEVLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60
L L V PGK+ + GE+AVV G A+ A+N L L + L +P+
Sbjct: 3 LKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNE--LWIPHYENPV 60
Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120
W + G P E + + + +EG+
Sbjct: 61 SWPI-------------GGELKPDGEHWTFTAEAINIATTFLKSEGIE------------ 95
Query: 121 RKQRTLPSLDIMVWSELPPGAG----LGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGS 176
L + +++ +EL +G LGSSAA +V V AL+T
Sbjct: 96 -----LTPVKMVIETELIDQSGAKYGLGSSAAATVAVINALMT---------------KF 135
Query: 177 WPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLK----------- 225
+PE + K A V+ GN S D + +GG + Y +K
Sbjct: 136 YPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWF 195
Query: 226 ---RLPALQI----------LLTNTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAIS 272
P LQI + T P ST LV+ + + + + LT + I
Sbjct: 196 MKEPWPMLQIETLEEPVPTFSVGWTGTPVSTGKLVSQIHAFKQEDSKNYQHFLTRNNEIM 255
Query: 273 LECERVL----GEMAAAPVPEQYLVLEEL 297
+ + E+ + + E +L+EL
Sbjct: 256 KQIIQAFHTKDEELLYSSIKENRRILQEL 284
>3K85-A nrPDB
Length = 357
Score = 55.0 bits (130), Expect = 6e-08, Method: Composition-based stats.
Identities = 57/351 (16%), Positives = 123/351 (35%), Gaps = 71/351 (20%)
Query: 20 HAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGD 79
++ ++G + L +NL + + ++G++ +N + + +
Sbjct: 24 YSDIYGGLILNATINLYAYCTIEETNSGRIEINAYDAQCCKSY----------------- 66
Query: 80 VPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPP 139
L + +G + L I + S I +++ P
Sbjct: 67 -----------------LSMSQLEIDGEASLIKGVYNRIIRDYRLEPKSFKITTYNDAPA 109
Query: 140 GAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGN 199
G+GLG+S+ VC+ A E ++ PL D ++ AYE ER G
Sbjct: 110 GSGLGTSSTMVVCILKA---FIEWLSLPLGDY------------ETSRLAYEIERKDLGL 154
Query: 200 PSGV-DNSVSTWGG-----------ALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALV 247
G D + +GG + + ++L T RS+ A++
Sbjct: 155 SGGKQDQYAAAFGGFNYMEFLQNDLVIVNPLKMKRWIVDELESSMVLYFTGRSRSSAAII 214
Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307
+ + + T+I+A+ + + + A + ++ +
Sbjct: 215 NEQKKNTSEGNQ------TAIEAMHKIKQSAI-DTKLALLKGDVGEFARILGEGWENKKK 267
Query: 308 L--GVGHASLDQLCQV-TAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEA 355
+ + + + + V T A + K++GAGGGG + +++P + V A
Sbjct: 268 MAGAITNPMIQEAFDVATGAGAMAGKVSGAGGGGFIMFVVEPTRKEEVVRA 318
>5YYS-A nrPDB
Length = 949
Score = 53.8 bits (127), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/268 (16%), Positives = 97/268 (36%), Gaps = 20/268 (7%)
Query: 85 LEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL-PSLDIMVWSELPPGAGL 143
L+ +K+ +P+ + G + Y ++ + + +++ + + +P G+GL
Sbjct: 657 LQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLLAAIPAGSGL 716
Query: 144 GSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI-NKWAYEGERVIHGNPSG 202
G+S+ + V A+ C + K+ + E L + W + V+ G
Sbjct: 717 GTSSILASTVLGAINDFCGLAWD--KNEICQRTLVLEQLLTTGGGWQDQYGGVLQGVKLL 774
Query: 203 VDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMA 262
+ +R+ + + +L T + R+ K ++A EI++
Sbjct: 775 QTEAGFAQSPLVRWLPDHLFTHPEYKDCHLLYY-TGITRTAKGILA----------EIVS 823
Query: 263 PLLTSIDAISLECERVLGE---MAAAPVPEQYLVLEELMDMNQHHLNALGVGH--ASLDQ 317
+ + + M A ++ L+ AL G +++
Sbjct: 824 SMFLNSSLHLNLLSEMKAHALDMNEAIQRGSFVEFGRLVGKTWEQNKALDSGTNPPAVEA 883
Query: 318 LCQVTAAHGLHSKLTGAGGGGCGITLLK 345
+ + + L KL GAGGGG + K
Sbjct: 884 IIDLIKDYTLGYKLPGAGGGGYLYMVAK 911
>4UT4-A nrPDB
Length = 346
Score = 52.3 bits (123), Expect = 3e-07, Method: Composition-based stats.
Identities = 51/264 (19%), Positives = 96/264 (36%), Gaps = 40/264 (15%)
Query: 84 TLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGL 143
T +Q+EK + ++ N L+L +Y ++ +L++ + + P G+GL
Sbjct: 60 TDQQVEKHQLISEPLEL---NGTLNLHKAVYNHMIRNYNHGKPIALELSTFCDAPAGSGL 116
Query: 144 GSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSG- 202
GSS+ V + A E + PL D I + AY ERV G G
Sbjct: 117 GSSSTLVVVMIKA---FVELLNLPLDDYA------------IAQLAYRIERVDCGLAGGR 161
Query: 203 VDNSVSTWGGALRYQQGKMSSLKRLP-----------ALQILLTNTKVPRSTKALVAGVR 251
D +T+GG + + P ++L T V R + ++
Sbjct: 162 QDQYSATFGGFNFMEFYAAARTIVNPLRIKNWVLCELEASLVLFYTGVSRESAKIIQD-- 219
Query: 252 SRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN--ALG 309
+ +++ +I+A+ L M A + + M + + A
Sbjct: 220 ----QSDNVVSHKTAAIEAMHGIKREAL-VMKEALLKGDFKAFVASMRLGWDNKKNSART 274
Query: 310 VGHASLDQLCQVT-AAHGLHSKLT 332
V +A +D++ A K++
Sbjct: 275 VSNAHIDEIYDAAIRAGAQAGKVS 298
>4P52-A nrPDB
Length = 331
Score = 45.8 bits (106), Expect = 3e-05, Method: Composition-based stats.
Identities = 42/241 (17%), Positives = 86/241 (35%), Gaps = 35/241 (14%)
Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187
++I + ++P G+GLGSSAA +V A+ + ++K +
Sbjct: 103 GIEIELTKKMPLGSGLGSSAASTVAGVYAINQLLG---------------NKMEVKDLLP 147
Query: 188 WAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRST-KAL 246
+A EGE + G+ + + +GG + + + +LP VP + +
Sbjct: 148 FAMEGEFLACGSAHADNVAPCLYGGFVLVRSYDPLDVVKLP----------VPANLYATI 197
Query: 247 VAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN 306
+ K + P ++ + V G + A + ++ M +
Sbjct: 198 IHPHVEVQTKDARNILPKQIALSQAVAQWGNV-GGLVAGLLMNDTSLIGRSM-QDHIVEP 255
Query: 307 ALGVGHASLDQLCQVT-AAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCGF 365
A V D + + A L ++G+G ++ + + QA+ GF
Sbjct: 256 ARSVLIPGFDDVKKAALDAGALGCSISGSGP-----SIFALSTSQEAAQKIGQAMKK-GF 309
Query: 366 D 366
D
Sbjct: 310 D 310
>3GON-A nrPDB
Length = 335
Score = 43.8 bits (101), Expect = 1e-04, Method: Composition-based stats.
Identities = 62/348 (17%), Positives = 113/348 (32%), Gaps = 55/348 (15%)
Query: 5 VLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWD 63
++ V GK+ GE+A++ G++AL + + + + ++ ++ + + +
Sbjct: 1 MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPN 60
Query: 64 VATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQ 123
L+ GD A + L + EG + + +
Sbjct: 61 -PDYSLIQETIALMGDFLAVRGQNLRPFSLAI---YGKMEREGKKFGLGSSGSVVVLVVK 116
Query: 124 RTLPSLDIMVW--------SELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIG 175
L ++ V S + G S C+AA + V DR +
Sbjct: 117 ALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAA-----EDLVLYQSFDRQKVA 171
Query: 176 SWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235
+W EE+ A ER WG ++ S +K L+
Sbjct: 172 AWLEEE-----NLATVLERD--------------WGFSI-------SQVKPTLECDFLV- 204
Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLE 295
TK + I LTS + L + + + EQ V
Sbjct: 205 -----GWTKEVAVSSHMVQQIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVAS 259
Query: 296 ELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITL 343
+L++ + + L QL + + +K +GAGGG CGI L
Sbjct: 260 KLLEGL-----STDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIAL 302
>4RPF-A nrPDB
Length = 310
Score = 35.4 bits (79), Expect = 0.042, Method: Composition-based stats.
Identities = 26/146 (17%), Positives = 47/146 (32%), Gaps = 28/146 (19%)
Query: 120 CRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPE 179
C++ + +++ +P G+GLGSSA V A+ C
Sbjct: 74 CQEMGKEIPVAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCG----------------- 116
Query: 180 EDLKSINKWAYEGERVIHGNPSGV---DNSVSTW-GGALRYQQGKMSSLKRLPALQ---- 231
+ L + GE + G SG DN + GG + + + +P
Sbjct: 117 QPLDKVTLLGMMGE--LEGRVSGSIHFDNVAPCYLGGMQLILEQEGYISQDVPGFSDWLW 174
Query: 232 -ILLTNTKVPRSTKALVAGVRSRLIK 256
+ KV + + + R
Sbjct: 175 VMAYPGIKVSTAEARAILPAQYRRQD 200
>3HUL-A nrPDB
Length = 298
Score = 34.2 bits (76), Expect = 0.12, Method: Composition-based stats.
Identities = 45/234 (19%), Positives = 80/234 (34%), Gaps = 41/234 (17%)
Query: 131 IMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAY 190
+++ ++PP GLGSS+A V T E + + A
Sbjct: 74 LVMTCDIPPARGLGSSSAAVVAGIELANTLAEL---------------NLSKEEKVRIAA 118
Query: 191 EGERVIHGNPSGVDNSVS---TWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALV 247
E E G+P V +V G L + + L AL + ++ S V
Sbjct: 119 EIE----GHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESRGV 174
Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307
P+ + P ++ + + M AA + + E+M+ + H
Sbjct: 175 ---------LPDTL-PFKEAV-----QASSIANVMIAAILRNDMTLAGEMMERDLWHEKY 219
Query: 308 LGVGHASLDQLCQVTAAHGLHSK-LTGAGGGGCGITLLKPGLERAKVEAAKQAL 360
L Q+ V G ++ L+GAG + + P K++ + Q L
Sbjct: 220 RSQLVPHLAQIRDVAKNQGAYAACLSGAGP---TVLVFAPRNLANKLQTSLQTL 270
>3BEA-A nrPDB
Length = 333
Score = 31.5 bits (69), Expect = 0.66, Method: Composition-based stats.
Identities = 30/185 (16%), Positives = 58/185 (31%), Gaps = 20/185 (10%)
Query: 135 SELPPGAGLGSSAAYSVCVAAAL----LTACEEVTNPLKDRGSIGSWPEEDLKSINKWAY 190
+ L G LG+ A V A A A +V + + E + + ++
Sbjct: 46 NNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSH 105
Query: 191 EGERV---------IHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPR 241
G+ HG P V +G L + + K L+ PA I
Sbjct: 106 LGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKSRVLETDPAFAI----ANSTL 161
Query: 242 STKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMN 301
ST+ L+ + + D + G +A + + ++M+ +
Sbjct: 162 STRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKI---GDFGLARDIMNDS 218
Query: 302 QHHLN 306
+ +
Sbjct: 219 NYIVK 223
>4JA0-A nrPDB
Length = 425
Score = 30.7 bits (67), Expect = 0.99, Method: Composition-based stats.
Identities = 23/131 (17%), Positives = 35/131 (26%), Gaps = 7/131 (5%)
Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125
+ L T + + ++Q E + GL + +
Sbjct: 295 DVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPP 354
Query: 126 LPSLDIMVWSELPPGAGLG-------SSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWP 178
L +WS L +GLG SAA L K S
Sbjct: 355 SDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAAQIIGLQDYLVWGRLRSKQLDMAHSLR 414
Query: 179 EEDLKSINKWA 189
+ D K N+ A
Sbjct: 415 QADKKLRNQTA 425
>4RBN-A nrPDB
Length = 794
Score = 30.3 bits (66), Expect = 1.6, Method: Composition-based stats.
Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 11/83 (13%)
Query: 195 VIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRL 254
+I SG+ + +GG L Q S + +T L+A +
Sbjct: 669 IIEAMASGLPTFATRYGGPLEIIQNNRSG---------FHIDPNQGAATADLIADFFEKN 719
Query: 255 IKFPEIMAPLLTSIDAISLECER 277
++ P+ + S A+ R
Sbjct: 720 LENPQEWERI--SQGALDRVASR 740
>5EKZ-A nrPDB
Length = 294
Score = 29.6 bits (64), Expect = 2.3, Method: Composition-based stats.
Identities = 15/99 (15%), Positives = 30/99 (30%), Gaps = 13/99 (13%)
Query: 256 KFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASL 315
+ I + L SI E P PE L ++ + + +++
Sbjct: 73 ERSRIFSKLTLSIRLAVKEG---------GPNPENNSSLANIL----ELCRSKNMPKSTI 119
Query: 316 DQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVE 354
+ + G++ G G GG + + K
Sbjct: 120 ESALKTEKNKGIYLLYEGRGPGGSSLLIEALSNSGPKCH 158
>3UY5-A nrPDB
Length = 428
Score = 29.2 bits (63), Expect = 3.0, Method: Composition-based stats.
Identities = 12/44 (27%), Positives = 19/44 (43%)
Query: 315 LDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQ 358
L +L H+ G G GG + L++P R + EA +
Sbjct: 163 LHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYE 206
>3F4A-A nrPDB
Length = 169
Score = 28.8 bits (62), Expect = 4.7, Method: Composition-based stats.
Identities = 14/70 (20%), Positives = 26/70 (37%), Gaps = 7/70 (10%)
Query: 202 GVDNSVSTWGGAL-------RYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRL 254
G+D+ T L Q+G ++L+ + + + + K SRL
Sbjct: 21 GMDSYSITNVKYLDPTELHRWMQEGHTTTLREPFQVVDVRGSDYMGGHIKDGWHYAYSRL 80
Query: 255 IKFPEIMAPL 264
+ PE + L
Sbjct: 81 KQDPEYLREL 90
>2YF3-A nrPDB
Length = 154
Score = 28.4 bits (61), Expect = 5.9, Method: Composition-based stats.
Identities = 12/51 (23%), Positives = 21/51 (41%)
Query: 268 IDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASLDQL 318
+D S E + + A + L +L + + L V + +LDQL
Sbjct: 50 LDEESAEVRAEIDHLLARQAAGEALSAGDLAPLAHELADLLYVTYGALDQL 100
>3FS5-A nrPDB
Length = 152
Score = 28.4 bits (61), Expect = 6.1, Method: Composition-based stats.
Identities = 10/50 (20%), Positives = 20/50 (40%)
Query: 215 RYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMAPL 264
Q+G ++L+ + + + + K SRL + PE + L
Sbjct: 20 WMQEGHTTTLREPFQVVDVRGSDYMGGHIKDGWHYAYSRLKQDPEYLREL 69
>4HGV-A nrPDB
Length = 495
Score = 28.0 bits (60), Expect = 7.8, Method: Composition-based stats.
Identities = 17/121 (14%), Positives = 36/121 (29%), Gaps = 17/121 (14%)
Query: 245 ALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHH 304
++ + L + + + + D I + + +++ + +
Sbjct: 187 RVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASS--- 243
Query: 305 LNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCG 364
+ + + L +L Q A G L P KV A+TG G
Sbjct: 244 IKRIEMTLPGLCELAQGGTAVGTG--------------LNAPVGFAEKVAEEIAAITGIG 289
Query: 365 F 365
F
Sbjct: 290 F 290
>5I0M-A nrPDB
Length = 138
Score = 27.6 bits (59), Expect = 9.8, Method: Composition-based stats.
Identities = 12/51 (23%), Positives = 21/51 (41%)
Query: 268 IDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASLDQL 318
+D S E + + A + L +L + + L V + +LDQL
Sbjct: 38 LDEESAEVRAEIDHLLARQAAGEALSAGDLAPLAHALADLLYVTYGALDQL 88
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.309 0.108 0.246
Lambda K H
0.267 0.0331 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,228,903
Number of Sequences: 36641
Number of extensions: 402412
Number of successful extensions: 1213
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1078
Number of HSP's gapped (non-prelim): 92
length of query: 395
length of database: 10,336,785
effective HSP length: 99
effective length of query: 296
effective length of database: 6,709,326
effective search space: 1985960496
effective search space used: 1985960496
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 59 (27.6 bits)