BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P17256 (395 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2R42-A nrPDB 798 0.0 2R3V-A nrPDB 639 0.0 4HAC-B nrPDB 118 5e-27 1KKH-A nrPDB 88 6e-18 2X7I-A nrPDB 59 4e-09 1WUU-A nrPDB 58 8e-09 2HFU-A nrPDB 56 2e-08 2AJ4-A nrPDB 39 0.006 2OI2-A nrPDB 39 0.006 3K85-A nrPDB 37 0.017 3V5R-A nrPDB 35 0.040 2A2C-A nrPDB 35 0.073 5XEA-A nrPDB 32 0.47 1PIE-A nrPDB 30 1.7 3VX8-B nrPDB 29 3.2 3K17-A nrPDB 29 3.4 4UT4-A nrPDB 28 5.8 2HKE-A nrPDB 28 9.7 >2R42-A nrPDB Length = 395 Score = 798 bits (2062), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/395 (100%), Positives = 395/395 (100%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395 >2R3V-A nrPDB Length = 396 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/393 (81%), Positives = 355/393 (90%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393 T CGFDC ETSIGAPGVS+HSATS++ V+QAL Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393 >4HAC-B nrPDB Length = 321 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 111/365 (30%), Positives = 164/365 (44%), Gaps = 81/365 (22%) Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVW 62 S ++ SAPGK+ L GEHAVV+G+ A+A A+ LRT + + LN Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRV--------RAELN---------- 60 Query: 63 DVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRK 122 D T+Q +G GL Y+ I + Sbjct: 61 DSITIQ-------------------------------SQIGRTGLDFEKHPYVSAVIEKM 89 Query: 123 QRTLP--SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 ++++P + + V S++P G+GLGSSAA ++ AL N L G Sbjct: 90 RKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGAL--------NELFGFGL------- 134 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 L+ I K +E E + G S D VST+GG + + + + P I++ +T V Sbjct: 135 SLQEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPERRK---LKTPDCGIVIGDTGVF 191 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 STK LVA VR +P+++ PL+TSI IS E+++ + Y + LM++ Sbjct: 192 SSTKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNV 244 Query: 301 NQHHLNALGVGHASLDQLC-QVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQA 359 NQ L+ALGV L QL AA +K+TGAGGGGC + L P K +A Sbjct: 245 NQGLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP----EKCNQVAEA 300 Query: 360 LTGCG 364 + G G Sbjct: 301 VAGAG 305 >1KKH-A nrPDB Length = 317 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 87/351 (24%), Positives = 142/351 (40%), Gaps = 77/351 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 +++ P KVIL GEHAVV+G A+++A++L + + ++ ++ LNL + Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLND---------- 55 Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125 L K GL + + N ++ F +C + T Sbjct: 56 -------------------------LNKSLGLNLNEIKN--INPNNFGDFKYCLCAIKNT 88 Query: 126 LPSLDI--------MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSW 177 L L+I + S++P GLGSSA+ ++ A + + Sbjct: 89 LDYLNIEPKTGFKINISSKIPISCGLGSSASITIGTIKA-----------------VSGF 131 Query: 178 PEEDLKS--INKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235 ++LK I K Y E+ I G S D S T+ G L + K +K + L Sbjct: 132 YNKELKDDEIAKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIK--GEFEEFLK 189 Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPL--LTSIDAISLECERVLGEMAAAPVPEQYLV 293 N K L+ R K E++ + + + D I E ++V+ E E + Sbjct: 190 NCKF------LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF-- 241 Query: 294 LEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLL 344 +LM N L L + LD++ + G +KLTGAGGGGC I L+ Sbjct: 242 -GKLMTKNHELLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291 >2X7I-A nrPDB Length = 308 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 87/340 (25%), Positives = 137/340 (40%), Gaps = 73/340 (21%) Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVL-RPQSNGKVSLNLPNVGIKQVWDVAT-L 67 + GK+IL GEHAV G+ A+AV N VL +G S +V ++D L Sbjct: 11 STGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDHL 70 Query: 68 QLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLP 127 + L F+E ++ P Sbjct: 71 KSLVNRFVELNNITEP-------------------------------------------- 86 Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187 L + + + LPP GLGSSAA +V A + S +E+L Sbjct: 87 -LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKAN 133 Query: 188 WAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPAL-QILLTNTKVPRSTKAL 246 WA E++ HG PSG+D G + +Q+G +LK L +++ +T V ST+ Sbjct: 134 WA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQA 190 Query: 247 VAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN 306 V V +L + P+ M+ + I + L V+ ++ L ++ + L Sbjct: 191 VHDVH-KLCEDPQYMSH-VKHIGKLVLRASDVIEH-------HKFEALADIFNECHADLK 241 Query: 307 ALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLK 345 AL V H ++QL ++ +G + KLTGAG GG + L K Sbjct: 242 ALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK 281 >1WUU-A nrPDB Length = 399 Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 107/377 (28%), Positives = 152/377 (40%), Gaps = 86/377 (22%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + + Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 95 Query: 66 TLQLLDTGFLEQGDVPAPTLEQ-LEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124 P PT ++ LE G PR +G+ + Y A Sbjct: 96 -------------QFPLPTAQRSLEP-----GTPRWANYVKGV-----IQYYPAA----- 127 Query: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184 LP +V S +P G GL SSA+ V L C D G+I + Sbjct: 128 PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR------- 173 Query: 185 INKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKM---------SSLKRL--PALQI 232 + + E G P G+ D +S G Q+G +SL L P L + Sbjct: 174 -AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAV 227 Query: 233 LLTNTKVPRSTKALVAGVRSRLIK----------FPEI-MAPLLTSIDAISLECER---- 277 L+TN+ V S + VR R + E+ + L + D +S E R Sbjct: 228 LITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARH 287 Query: 278 VLGEM------AAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT-AAHGLH- 328 V+GE+ AAA Y LM + L + V LDQL + A G++ Sbjct: 288 VVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYG 347 Query: 329 SKLTGAGGGGCGITLLK 345 S++TG G GGC +TLL+ Sbjct: 348 SRMTGGGFGGCTVTLLE 364 >2HFU-A nrPDB Length = 332 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 82/346 (23%), Positives = 135/346 (39%), Gaps = 70/346 (20%) Query: 12 GKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLD 71 GKVIL GEH VVHG A+ ++ T L +++ +P LQ+ D Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRL------EINPGVPG-----------LQVDD 62 Query: 72 TGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDI 131 G + EQ++ + V + + +GL + Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQLVLDHLKVDLSGDGLKMF--------------------- 101 Query: 132 MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYE 191 + L P +G+G+SA+ V + AL E L D + +N A+ Sbjct: 102 -IGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145 Query: 192 GERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQ----ILLTNTKVPRSTKALV 247 GE HG PSG DN+ +T+GG + Y++ S+ + A Q +++ T + ST +V Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205 Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVL--GEMAAAPVPEQYLVLEELMDMNQHHL 305 V + P L + I + L G++ L +LM+ N Sbjct: 206 NDVHKMKQQQPVQFKRLYDNYTHIVSQAREALQKGDLQR---------LGQLMNANHDLC 256 Query: 306 NALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLER 350 + V L+ + Q +G L +KL+G G GG + L +R Sbjct: 257 RQIDVSCRELESIVQTCRTYGALGAKLSGTGRGGIAVALAASSDQR 302 >2AJ4-A nrPDB Length = 548 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 2/47 (4%) Query: 315 LDQLCQVTAAHGLH-SKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 +D++C + ++G + S+LTGAG GGC + L+ PG +E K+AL Sbjct: 468 IDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEAL 513 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTA 160 L L + ++P G+GL SSAA+ VA A++ A Sbjct: 171 LAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKA 205 >2OI2-A nrPDB Length = 292 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 13/154 (8%) Query: 193 ERVIHGNPSGVDNSVSTWGGALRYQQG-KMSSLKRLPALQILLTNTKVPRSTKALVAGVR 251 E + H NPSG+D +R+ + + L+ + +++ +T V T+ + V+ Sbjct: 124 EMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQ 183 Query: 252 SRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVG 311 ++ + P L ++ ++ + E + + A L +++ HL +GV Sbjct: 184 NK----GKDALPFLHALGELTQQAEIAISQKDAEG-------LGQILSQAHLHLKEIGVS 232 Query: 312 HASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLL 344 D L + +HG L +K++G G GGC I L+ Sbjct: 233 SLEADSLVETALSHGALGAKMSGGGLGGCIIALV 266 >3K85-A nrPDB Length = 357 Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 16/105 (15%) Query: 115 LYLAICRKQRTLP-SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGS 173 +Y I R R P S I +++ P G+GLG+S+ VC+ A + E ++ PL D Sbjct: 84 VYNRIIRDYRLEPKSFKITTYNDAPAGSGLGTSSTMVVCILKAFI---EWLSLPLGDY-- 138 Query: 174 IGSWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQ 218 ++ AYE ER G G + + G Y + Sbjct: 139 ----------ETSRLAYEIERKDLGLSGGKQDQYAAAFGGFNYME 173 >3V5R-A nrPDB Length = 505 Score = 35.4 bits (80), Expect = 0.040, Method: Compositional matrix adjust. Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 316 DQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 +Q+C + A+G S+LTGAG GGC I L+ P VE ++AL Sbjct: 426 NQICSIALANGSFGSRLTGAGWGGCTIHLV-PSGANGNVEQVRKAL 470 >2A2C-A nrPDB Length = 478 Score = 34.7 bits (78), Expect = 0.073, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 300 MNQHHLNALGVGHAS---LDQLCQVTAAHGLH-SKLTGAGGGGCGITLL 344 MNQ H++ + S LDQL + G S+LTGAG GGC ++++ Sbjct: 384 MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMV 432 >5XEA-A nrPDB Length = 466 Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 8/71 (11%) Query: 244 KALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYL-----VLEELM 298 +A A + SR + EI+ +++SI I ER++G + APV +++ +L + + Sbjct: 300 RASFAELDSRFRQLSEILDTVISSIAKID---ERLIGRLIKAPVSSRFISEDKFLLHQCV 356 Query: 299 DMNQHHLNALG 309 D ++ N +G Sbjct: 357 DSVANNTNCVG 367 >1PIE-A nrPDB Length = 419 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%) Query: 4 EVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSL---NLPNVGI 58 EV +PG++ L GEH +G ++ + T + R + + KV L N P +G+ Sbjct: 47 EVEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKKVKLYSENFPKLGV 104 >3VX8-B nrPDB Length = 292 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 27/53 (50%) Query: 42 RPQSNGKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKV 94 +P+ GK NLP++ + + T+Q + T F + D P +E+ ++ V Sbjct: 93 KPKDKGKEEDNLPSMDALDINEKNTIQSIPTYFGGEEDDDIPDMEEFDEADNV 145 >3K17-A nrPDB Length = 365 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 58/244 (23%), Positives = 91/244 (37%), Gaps = 52/244 (21%) Query: 2 LSEVLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 L L V PGK+ + GE+AVV G A+ A+N ++ L + + + L +P+ Sbjct: 3 LKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVN--RYITLTLEDSERNELWIPHYENPV 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 W + G P E + + + +EG+ L Sbjct: 61 SWPI-------------GGELKPDGEHWTFTAEAINIATTFLKSEGIEL----------- 96 Query: 121 RKQRTLPSLDIMVWSEL--PPGA--GLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGS 176 + +++ +EL GA GLGSSAA +V V AL+T Sbjct: 97 ------TPVKMVIETELIDQSGAKYGLGSSAAATVAVINALMTKF--------------- 135 Query: 177 WPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTN 236 +PE + K A V+ GN S D + +GG + Y +K A + L Sbjct: 136 YPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWF 195 Query: 237 TKVP 240 K P Sbjct: 196 MKEP 199 >4UT4-A nrPDB Length = 346 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 16/86 (18%) Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187 +L++ + + P G+GLGSS+ V + A + E + PL D +I + Sbjct: 101 ALELSTFCDAPAGSGLGSSSTLVVVMIKAFV---ELLNLPLDD------------YAIAQ 145 Query: 188 WAYEGERVIHGNPSGVDNSVS-TWGG 212 AY ERV G G + S T+GG Sbjct: 146 LAYRIERVDCGLAGGRQDQYSATFGG 171 >2HKE-A nrPDB Length = 380 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 27/49 (55%) Query: 118 AICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTN 166 + C ++ ++I+ + P AG+ SSA+ ++AAL+ A + TN Sbjct: 87 STCPEELKNKKVNIVSENNFPTAAGMASSASGYCAMSAALIRAFKSTTN 135 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2R42-A nrPDB 535 e-152 2R3V-A nrPDB 501 e-142 4HAC-B nrPDB 257 4e-69 2HFU-A nrPDB 257 5e-69 1KKH-A nrPDB 256 9e-69 1WUU-A nrPDB 226 1e-59 2X7I-A nrPDB 222 2e-58 Sequences not found previously or not previously below threshold: 2DEI-A nrPDB 107 8e-24 1S4E-A nrPDB 102 2e-22 2OI2-A nrPDB 92 5e-19 2A2C-A nrPDB 86 2e-17 1PIE-A nrPDB 86 2e-17 2AJ4-A nrPDB 69 3e-12 3V5R-A nrPDB 66 2e-11 4N3O-A nrPDB 57 1e-08 3K17-A nrPDB 55 5e-08 3K85-A nrPDB 55 6e-08 5YYS-A nrPDB 54 1e-07 4UT4-A nrPDB 52 3e-07 4P52-A nrPDB 46 3e-05 3GON-A nrPDB 44 1e-04 4RPF-A nrPDB 35 0.042 3HUL-A nrPDB 34 0.12 3BEA-A nrPDB 32 0.66 4JA0-A nrPDB 31 0.99 4RBN-A nrPDB 30 1.6 5EKZ-A nrPDB 30 2.3 3UY5-A nrPDB 29 3.0 3F4A-A nrPDB 29 4.7 2YF3-A nrPDB 28 5.9 3FS5-A nrPDB 28 6.1 4HGV-A nrPDB 28 7.8 5I0M-A nrPDB 28 9.8 >2R42-A nrPDB Length = 395 Score = 535 bits (1378), Expect = e-152, Method: Composition-based stats. Identities = 395/395 (100%), Positives = 395/395 (100%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQALGL 395 >2R3V-A nrPDB Length = 396 Score = 501 bits (1289), Expect = e-142, Method: Composition-based stats. Identities = 322/393 (81%), Positives = 355/393 (90%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 Query: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393 T CGFDC ETSIGAPGVS+HSATS++ V+QAL Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393 >4HAC-B nrPDB Length = 321 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 109/365 (29%), Positives = 163/365 (44%), Gaps = 81/365 (22%) Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVW 62 S ++ SAPGK+ L GEHAVV+G+ A+A A+ LRT + ++ Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRVR------------------AELN 60 Query: 63 DVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRK 122 D T+Q +G GL Y+ I + Sbjct: 61 DSITIQS-------------------------------QIGRTGLDFEKHPYVSAVIEKM 89 Query: 123 QRTLP--SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 ++++P + + V S++P G+GLGSSAA ++ AL N L G Sbjct: 90 RKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGAL--------NELFGFGL------- 134 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 L+ I K +E E + G S D VST+GG + + + + P I++ +T V Sbjct: 135 SLQEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPERRK---LKTPDCGIVIGDTGVF 191 Query: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 STK LVA VR +P+++ PL+TSI IS E+++ + Y + LM++ Sbjct: 192 SSTKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNV 244 Query: 301 NQHHLNALGVGHASLDQLC-QVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQA 359 NQ L+ALGV L QL AA +K+TGAGGGGC + L P K +A Sbjct: 245 NQGLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP----EKCNQVAEA 300 Query: 360 LTGCG 364 + G G Sbjct: 301 VAGAG 305 >2HFU-A nrPDB Length = 332 Score = 257 bits (657), Expect = 5e-69, Method: Composition-based stats. Identities = 81/347 (23%), Positives = 133/347 (38%), Gaps = 66/347 (19%) Query: 12 GKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLD 71 GKVIL GEH VVHG A+ ++ T L +++ +P LQ+ D Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRL------EINPGVPG-----------LQVDD 62 Query: 72 TGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDI 131 G + EQ++ + V + + +GL + Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQLVLDHLKVDLSGDGLKMF--------------------- 101 Query: 132 MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYE 191 + L P +G+G+SA+ V + AL E L D + +N A+ Sbjct: 102 -IGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145 Query: 192 GERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQ----ILLTNTKVPRSTKALV 247 GE HG PSG DN+ +T+GG + Y++ S+ + A Q +++ T + ST +V Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205 Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307 V + P L + I + L L +LM+ N Sbjct: 206 NDVHKMKQQQPVQFKRLYDNYTHIVSQAREAL-------QKGDLQRLGQLMNANHDLCRQ 258 Query: 308 LGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKV 353 + V L+ + Q +G L +KL+G G GG + L +R + Sbjct: 259 IDVSCRELESIVQTCRTYGALGAKLSGTGRGGIAVALAASSDQRDAI 305 >1KKH-A nrPDB Length = 317 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 87/351 (24%), Positives = 142/351 (40%), Gaps = 77/351 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 +++ P KVIL GEHAVV+G A+++A++L + + ++ ++ LNL + Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLND---------- 55 Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125 L K GL + + N ++ F +C + T Sbjct: 56 -------------------------LNKSLGLNLNEIKN--INPNNFGDFKYCLCAIKNT 88 Query: 126 LPSLDI--------MVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSW 177 L L+I + S++P GLGSSA+ ++ A + + Sbjct: 89 LDYLNIEPKTGFKINISSKIPISCGLGSSASITIGTIKA-----------------VSGF 131 Query: 178 PEEDLK--SINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235 ++LK I K Y E+ I G S D S T+ G L + K +K + L Sbjct: 132 YNKELKDDEIAKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIK--GEFEEFLK 189 Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPL--LTSIDAISLECERVLGEMAAAPVPEQYLV 293 N K L+ R K E++ + + + D I E ++V+ E E + Sbjct: 190 NCKF------LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF-- 241 Query: 294 LEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLL 344 +LM N L L + LD++ + G +KLTGAGGGGC I L+ Sbjct: 242 -GKLMTKNHELLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291 >1WUU-A nrPDB Length = 399 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 105/393 (26%), Positives = 151/393 (38%), Gaps = 84/393 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + + Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 95 Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125 P PT ++ G PR +G+ + Y A Sbjct: 96 -------------QFPLPTAQR----SLEPGTPRWANYVKGV-----IQYYPAA-----P 128 Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI 185 LP +V S +P G GL SSA+ V L C D G+I + Sbjct: 129 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR-------- 173 Query: 186 NKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKM---------SSLKRL--PALQIL 233 + + E G P G+ D +S G Q+G +SL L P L +L Sbjct: 174 AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAVL 228 Query: 234 LTNTKVPRSTKALVAGVRSRLIKF-----------PEIMAPLLTSIDAISLECER----V 278 +TN+ V S + VR R + + L + D +S E R V Sbjct: 229 ITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHV 288 Query: 279 LGEM------AAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT-AAHGL-HS 329 +GE+ AAA Y LM + L + V LDQL + A G+ S Sbjct: 289 VGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGS 348 Query: 330 KLTGAGGGGCGITLLKPGLERAKVEAAKQALTG 362 ++TG G GGC +TLL+ + ++ G Sbjct: 349 RMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGG 381 >2X7I-A nrPDB Length = 308 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 89/360 (24%), Positives = 142/360 (39%), Gaps = 76/360 (21%) Query: 9 SAPGKVILHGEHAVVHGKVALAVALNLRTFLVL-RPQSNGKVSLNLPNVGIKQVWDVAT- 66 + GK+IL GEHAV G+ A+AV N VL +G S +V ++D Sbjct: 10 ESTGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDH 69 Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL 126 L+ L F+E ++ P Sbjct: 70 LKSLVNRFVELNNITEP------------------------------------------- 86 Query: 127 PSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSIN 186 L + + + LPP GLGSSAA +V A + S +E+L Sbjct: 87 --LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKA 132 Query: 187 KWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPAL-QILLTNTKVPRSTKA 245 WA E++ HG PSG+D G + +Q+G +LK L +++ +T V ST+ Sbjct: 133 NWA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQ 189 Query: 246 LVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHL 305 V V L + P+ M+ + I + L V+ ++ L ++ + L Sbjct: 190 AVHDVHK-LCEDPQYMSHV-KHIGKLVLRASDVIEH-------HKFEALADIFNECHADL 240 Query: 306 NALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCG 364 AL V H ++QL ++ +G + KLTGAG GG + L K + + +A+ G Sbjct: 241 KALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK---DLPTAKNIVKAVEKAG 297 >2DEI-A nrPDB Length = 350 Score = 107 bits (267), Expect = 8e-24, Method: Composition-based stats. Identities = 67/370 (18%), Positives = 116/370 (31%), Gaps = 79/370 (21%) Query: 5 VLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDV 64 ++ V +PG+V L GEH + +A+NL T + + +G+V L + G ++ + + Sbjct: 1 MIKVKSPGRVNLIGEHTDYTYGYVMPMAINLYT--KIEAEKHGEVILYSEHFGEERKFSL 58 Query: 65 ATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124 L+ +G+ + + Sbjct: 59 NDLRKE---------------------------NSWIDYVKGI--------FWVLKESDY 83 Query: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184 + + V LP GAGL SSA++ V + L + L S Sbjct: 84 EVGGIKGRVSGNLPLGAGLSSSASFEVGILETLDKLYNLKLDSL---------------S 128 Query: 185 INKWAYEGERVIHGNPSGV-DNSVSTWG--GALRYQQGKMSSLKRLP---ALQILLTNTK 238 A + E G P G+ D +G G + + + +P + IL+ T Sbjct: 129 KVLLAKKAENEFVGVPCGILDQFAVVFGREGNVIFLDTHTLDYEYIPFPKDVSILVFYTG 188 Query: 239 VPRSTKALVAGVRS------------------RLIKFPEIMAPLLTSIDAISLECERVLG 280 V R + R R + ++ I E RVL Sbjct: 189 VRRELASSEYAERKHIAEESLKILGKGSSKEVREGELSKLPPLHRKFFGYIVRENARVL- 247 Query: 281 EMAAAPVPEQYLVLEELMDMNQ-HHLNALGVGHASLDQLCQ-VTAAHGLHSKLTGAGGGG 338 E+ A + +++ V LD + ++LTGAG GG Sbjct: 248 EVRDALKEGNVEEVGKILTTAHWDLAKNYEVSCKELDFFVERALKLGAYGARLTGAGFGG 307 Query: 339 CGITLLKPGL 348 I L+ Sbjct: 308 SAIALVDKED 317 >1S4E-A nrPDB Length = 352 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 69/365 (18%), Positives = 107/365 (29%), Gaps = 79/365 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 + V +PG+V L GEH + +A++L T + Sbjct: 4 ITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTIITAEKYD-------------------- 43 Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125 +QL F E+ L + + EG Sbjct: 44 KVQLYSEHFNEEKTFTLDNLTKEGSWIDYVKGVLWVLIQEGYK----------------- 86 Query: 126 LPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI 185 + L + +LP GAGL SSA++ V + L +PLK Sbjct: 87 IGGLKGKITGDLPLGAGLSSSASFEVGILEVLNQLYNLNIDPLKKALLAK---------- 136 Query: 186 NKWAYEGERVIHGNPSGV-DNSVSTWGG-----ALRYQQGKMSSLKRLPALQILLTNTKV 239 + E G P G+ D +G L Q + + + +L+ T V Sbjct: 137 -----KAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTLQYEYIPFPKDVSVLVFYTGV 191 Query: 240 PRSTKALVAGVRSR----------LIKFPEIMAPLL--------TSIDAISLECERVLGE 281 R + R R E+ L I E RVL E Sbjct: 192 KRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGKLPPLHRKFFSYIVRENARVL-E 250 Query: 282 MAAAPVPEQYLVLEELMDMNQ-HHLNALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGC 339 + A + +++ V LD + G ++LTGAG GG Sbjct: 251 VRDALKEGDIEKVGKILTTAHWDLAENYRVSCEELDFFVKKAMELGAYGARLTGAGFGGS 310 Query: 340 GITLL 344 I L+ Sbjct: 311 AIALV 315 >2OI2-A nrPDB Length = 292 Score = 91.6 bits (225), Expect = 5e-19, Method: Composition-based stats. Identities = 68/346 (19%), Positives = 125/346 (36%), Gaps = 82/346 (23%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 M +V + A K+IL GEHAVV+G A+++ L +V + V + Sbjct: 1 MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPL-------------LEVEVTCKVVPAES 47 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 W + L + +Y ++ Sbjct: 48 PWRLYEEDTLS-----------------------------------------MAVYASLE 66 Query: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 T + + S +P G+GSSAA S+ A+ L Sbjct: 67 YLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDY---YQADLP----------H 113 Query: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQG-KMSSLKRLPALQILLTNTKV 239 D+ I E + H NPSG+D +R+ + + L+ + +++ +T V Sbjct: 114 DVLEI--LVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGV 171 Query: 240 PRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMD 299 T+ + V+++ P L ++ ++ + E + + + L +++ Sbjct: 172 YGHTREAIQVVQNKGKD----ALPFLHALGELTQQAEIAISQ-------KDAEGLGQILS 220 Query: 300 MNQHHLNALGVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLL 344 HL +GV D L + +HG L +K++G G GGC I L+ Sbjct: 221 QAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALV 266 >2A2C-A nrPDB Length = 478 Score = 86.2 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 66/384 (17%), Positives = 122/384 (31%), Gaps = 43/384 (11%) Query: 8 VSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSL-NLPNVGIKQVWDVAT 66 V APG+V + GEH G L +A+ + + P + L N + Sbjct: 58 VRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVKTYALQLANTNPLYPDFSTSANN 117 Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAI--CRKQR 124 +Q+ T L E +C+ + + + L A+ C Sbjct: 118 IQIDKTKPLWHNYFLCGLKGIQEHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLV 177 Query: 125 TLPSLDIMVWSELPP--------------GAGLGSSAAYSVCVAAA-LLTACEEVTNPLK 169 TL L + S++ G G+ S ++ A L+ +K Sbjct: 178 TLTVLGRNL-SKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVK 236 Query: 170 DRGSIGSWPEEDLKSINKWA------YEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSS 223 +NK A E + W LR ++ + Sbjct: 237 LPSGAVFVIANSCVEMNKAATSHFNIRVMECRLAAK-LLAKYKSLQWDKVLRLEEVQAKL 295 Query: 224 LKRLPALQILLTNT---------KVPRSTKALVAGVRSRLIK---FPEIMAPLLTSIDAI 271 L + ++ + ++ R + +R++++ ++ L + Sbjct: 296 GISLEEMLLVTEDALHPEPYNPEEICRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHV 355 Query: 272 SLECERVLG--EMAAAPVPEQYLVLEELMDMNQHHLNA-LGVGHASLDQLCQVTAAHGL- 327 E RVL ++ +L ELM+ + LDQL + G Sbjct: 356 YSEAARVLQFKKICEEAPENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQ 415 Query: 328 HSKLTGAGGGGCGITLLKPGLERA 351 S+LTGAG GGC ++++ P + Sbjct: 416 GSRLTGAGWGGCTVSMV-PADKLP 438 >1PIE-A nrPDB Length = 419 Score = 86.2 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 71/394 (18%), Positives = 126/394 (31%), Gaps = 88/394 (22%) Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQL 69 +PG++ L GEH +G ++ + T + R + + KV L N Sbjct: 53 SPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKKVKLYSEN-------------- 98 Query: 70 LDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSL 129 F + G + E +K + +G+ ++ Y Sbjct: 99 ----FPKLGVIEFDLDEVEKKDGE-----LWSNYVKGMIVMLKGAGYEIDK-------GF 142 Query: 130 DIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWA 189 ++++ E+P +GL SSA+ + V L L + + Sbjct: 143 ELLIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRL---------------ELVQLG 187 Query: 190 YEGERVIHGNPSGV-DNSVSTWGGALRYQQGKMSSLK------RLPALQILLTNTKVPRS 242 + E G SG+ D +G + + ++LK L I++ NT PR+ Sbjct: 188 QKTENDYIGVNSGILDQFAIGFGEVKKAIELDCNTLKYEMVPVELRDYDIVIMNTNKPRA 247 Query: 243 TKALVAGVRSRLIKFPEIMAPLLTSID----------------------AISLECERVLG 280 R + E + + T +D + + Sbjct: 248 LTESKYN--ERFAETREALKRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRARHAVY 305 Query: 281 E------MAAAPVPEQYLVLEELMDMNQHHL-NALGVGHASLDQLCQVT--AAHGLHSKL 331 E A V EL++ + L + V LD L + A L +++ Sbjct: 306 ENNRTKIAQKAFVAGNLTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGVLGARM 365 Query: 332 TGAGGGGCGITLLKP---GLERAKVEAAKQALTG 362 TGAG GGC I L+ R V + + G Sbjct: 366 TGAGFGGCAIALVAHDNVSAFRKAVGQVYEEVVG 399 >2AJ4-A nrPDB Length = 548 Score = 69.2 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 4/115 (3%) Query: 249 GVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNAL 308 VR +++K + + S L+ +++ + + + LM+ +Q + L Sbjct: 402 PVRFQVLKLYQRAKHVY-SESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKL 460 Query: 309 -GVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALT 361 +D++C + ++G S+LTGAG GGC + L+ PG +E K+AL Sbjct: 461 YECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEALA 514 Score = 57.7 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 37/243 (15%) Query: 10 APGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQL 69 +PG+V L GEH L +A++ ++ + S+ L N K L Sbjct: 70 SPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDL-- 127 Query: 70 LDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSL 129 L+ V GL + L+ F L L Sbjct: 128 ----PLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERF---------ASAPLAGL 174 Query: 130 DIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWA 189 + ++P G+GL SSAA+ VA A++ A ++G +++ + Sbjct: 175 QVFCEGDVPTGSGLSSSAAFICAVALAVVKA------------NMGPGYHMSKQNLMRIT 222 Query: 190 YEGERVIHGNPSGVDNSVSTWGG-----ALRYQQGKMSSLKRLPALQ-----ILLTNTKV 239 E + N G+D + S G + ++ ++ + P L+ ++ NT V Sbjct: 223 VVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLV 282 Query: 240 PRS 242 + Sbjct: 283 VSN 285 >3V5R-A nrPDB Length = 505 Score = 66.2 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 4/114 (3%) Query: 249 GVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNAL 308 VR +++K + + S L+ +++ + + LM+ +Q + L Sbjct: 359 PVRFQVLKLYQRAKHVY-SESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKL 417 Query: 309 -GVGHASLDQLCQVTAAHG-LHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 +Q+C + A+G S+LTGAG GGC I L+ P VE ++AL Sbjct: 418 YECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLV-PSGANGNVEQVRKAL 470 Score = 58.5 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 41/250 (16%), Positives = 81/250 (32%), Gaps = 47/250 (18%) Query: 7 LVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVAT 66 + +PG+V L GEH L +A+++ ++ S+ L N K Sbjct: 26 IARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFD 85 Query: 67 LQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL 126 L L + V + +A YL + Sbjct: 86 LPLDGSYMAIDPSVSE-----------------WSNYFKCGLHVAHSYLKKIAPERFNNT 128 Query: 127 PSLDIMV--WSELPPGAGLGS--SAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDL 182 P + + S++P G GL S + A ++ A ++G + Sbjct: 129 PLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRA----------------NMGKNFDISK 172 Query: 183 KSINKWAYEGERVIHGNPSGVDNSVSTWGG-----ALRYQQGKMSSLKRLPALQ-----I 232 K + + E + N G+D + S +G + ++ ++ + P L+ Sbjct: 173 KDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISF 232 Query: 233 LLTNTKVPRS 242 ++ NT V + Sbjct: 233 VIANTLVKSN 242 >4N3O-A nrPDB Length = 342 Score = 56.9 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 29/267 (10%) Query: 102 VGNEG-LSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTA 160 +GN+G L + +Y + ++ L S + +S++P G+GLG S+ V V A Sbjct: 75 LGNDGKLDIFKSIYNRIVKDFTKKPL-SFSLHTYSDVPSGSGLGGSSTLVVGVIKA---F 130 Query: 161 CEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQG 219 E + PL + I K AYE ER G G D +T+GG + Sbjct: 131 AEWLNLPLGEY------------EIAKLAYEIEREDLGIVGGAQDQYAATFGGFNFMEFY 178 Query: 220 KMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSI-DAISLECERV 278 + P + + N V + + +I + D SLE Sbjct: 179 NNKRVIVNP---LRIKNWIASELEARTVLYFTNITREAKDIEEHKKGKLGDEKSLEAMHA 235 Query: 279 LGE----MAAAPVPEQYLVLEELMDMNQHHLNALG--VGHASLDQLCQVTAAHGLHS-KL 331 + + M A + L +++ + + V + L+++ ++ +G +S K Sbjct: 236 IKQDAIKMKEALFRADFGTLAQILGKSWRSKKIISEIVSNDELERIYKLAIDNGAYSGKT 295 Query: 332 TGAGGGGCGITLLKPGLERAKVEAAKQ 358 +GAG GG + P + ++A ++ Sbjct: 296 SGAGAGGFMFFFVDPTKKYNLIKALRK 322 >3K17-A nrPDB Length = 365 Score = 55.4 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 71/329 (21%), Positives = 114/329 (34%), Gaps = 80/329 (24%) Query: 2 LSEVLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 L L V PGK+ + GE+AVV G A+ A+N L L + L +P+ Sbjct: 3 LKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNE--LWIPHYENPV 60 Query: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 W + G P E + + + +EG+ Sbjct: 61 SWPI-------------GGELKPDGEHWTFTAEAINIATTFLKSEGIE------------ 95 Query: 121 RKQRTLPSLDIMVWSELPPGAG----LGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGS 176 L + +++ +EL +G LGSSAA +V V AL+T Sbjct: 96 -----LTPVKMVIETELIDQSGAKYGLGSSAAATVAVINALMT---------------KF 135 Query: 177 WPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLK----------- 225 +PE + K A V+ GN S D + +GG + Y +K Sbjct: 136 YPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWF 195 Query: 226 ---RLPALQI----------LLTNTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAIS 272 P LQI + T P ST LV+ + + + + LT + I Sbjct: 196 MKEPWPMLQIETLEEPVPTFSVGWTGTPVSTGKLVSQIHAFKQEDSKNYQHFLTRNNEIM 255 Query: 273 LECERVL----GEMAAAPVPEQYLVLEEL 297 + + E+ + + E +L+EL Sbjct: 256 KQIIQAFHTKDEELLYSSIKENRRILQEL 284 >3K85-A nrPDB Length = 357 Score = 55.0 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 57/351 (16%), Positives = 123/351 (35%), Gaps = 71/351 (20%) Query: 20 HAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGD 79 ++ ++G + L +NL + + ++G++ +N + + + Sbjct: 24 YSDIYGGLILNATINLYAYCTIEETNSGRIEINAYDAQCCKSY----------------- 66 Query: 80 VPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPP 139 L + +G + L I + S I +++ P Sbjct: 67 -----------------LSMSQLEIDGEASLIKGVYNRIIRDYRLEPKSFKITTYNDAPA 109 Query: 140 GAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGN 199 G+GLG+S+ VC+ A E ++ PL D ++ AYE ER G Sbjct: 110 GSGLGTSSTMVVCILKA---FIEWLSLPLGDY------------ETSRLAYEIERKDLGL 154 Query: 200 PSGV-DNSVSTWGG-----------ALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALV 247 G D + +GG + + ++L T RS+ A++ Sbjct: 155 SGGKQDQYAAAFGGFNYMEFLQNDLVIVNPLKMKRWIVDELESSMVLYFTGRSRSSAAII 214 Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307 + + + T+I+A+ + + + A + ++ + Sbjct: 215 NEQKKNTSEGNQ------TAIEAMHKIKQSAI-DTKLALLKGDVGEFARILGEGWENKKK 267 Query: 308 L--GVGHASLDQLCQV-TAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEA 355 + + + + + V T A + K++GAGGGG + +++P + V A Sbjct: 268 MAGAITNPMIQEAFDVATGAGAMAGKVSGAGGGGFIMFVVEPTRKEEVVRA 318 >5YYS-A nrPDB Length = 949 Score = 53.8 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 44/268 (16%), Positives = 97/268 (36%), Gaps = 20/268 (7%) Query: 85 LEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTL-PSLDIMVWSELPPGAGL 143 L+ +K+ +P+ + G + Y ++ + + +++ + + +P G+GL Sbjct: 657 LQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLLAAIPAGSGL 716 Query: 144 GSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSI-NKWAYEGERVIHGNPSG 202 G+S+ + V A+ C + K+ + E L + W + V+ G Sbjct: 717 GTSSILASTVLGAINDFCGLAWD--KNEICQRTLVLEQLLTTGGGWQDQYGGVLQGVKLL 774 Query: 203 VDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMA 262 + +R+ + + +L T + R+ K ++A EI++ Sbjct: 775 QTEAGFAQSPLVRWLPDHLFTHPEYKDCHLLYY-TGITRTAKGILA----------EIVS 823 Query: 263 PLLTSIDAISLECERVLGE---MAAAPVPEQYLVLEELMDMNQHHLNALGVGH--ASLDQ 317 + + + M A ++ L+ AL G +++ Sbjct: 824 SMFLNSSLHLNLLSEMKAHALDMNEAIQRGSFVEFGRLVGKTWEQNKALDSGTNPPAVEA 883 Query: 318 LCQVTAAHGLHSKLTGAGGGGCGITLLK 345 + + + L KL GAGGGG + K Sbjct: 884 IIDLIKDYTLGYKLPGAGGGGYLYMVAK 911 >4UT4-A nrPDB Length = 346 Score = 52.3 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 51/264 (19%), Positives = 96/264 (36%), Gaps = 40/264 (15%) Query: 84 TLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGL 143 T +Q+EK + ++ N L+L +Y ++ +L++ + + P G+GL Sbjct: 60 TDQQVEKHQLISEPLEL---NGTLNLHKAVYNHMIRNYNHGKPIALELSTFCDAPAGSGL 116 Query: 144 GSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSG- 202 GSS+ V + A E + PL D I + AY ERV G G Sbjct: 117 GSSSTLVVVMIKA---FVELLNLPLDDYA------------IAQLAYRIERVDCGLAGGR 161 Query: 203 VDNSVSTWGGALRYQQGKMSSLKRLP-----------ALQILLTNTKVPRSTKALVAGVR 251 D +T+GG + + P ++L T V R + ++ Sbjct: 162 QDQYSATFGGFNFMEFYAAARTIVNPLRIKNWVLCELEASLVLFYTGVSRESAKIIQD-- 219 Query: 252 SRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN--ALG 309 + +++ +I+A+ L M A + + M + + A Sbjct: 220 ----QSDNVVSHKTAAIEAMHGIKREAL-VMKEALLKGDFKAFVASMRLGWDNKKNSART 274 Query: 310 VGHASLDQLCQVT-AAHGLHSKLT 332 V +A +D++ A K++ Sbjct: 275 VSNAHIDEIYDAAIRAGAQAGKVS 298 >4P52-A nrPDB Length = 331 Score = 45.8 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 42/241 (17%), Positives = 86/241 (35%), Gaps = 35/241 (14%) Query: 128 SLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINK 187 ++I + ++P G+GLGSSAA +V A+ + ++K + Sbjct: 103 GIEIELTKKMPLGSGLGSSAASTVAGVYAINQLLG---------------NKMEVKDLLP 147 Query: 188 WAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRST-KAL 246 +A EGE + G+ + + +GG + + + +LP VP + + Sbjct: 148 FAMEGEFLACGSAHADNVAPCLYGGFVLVRSYDPLDVVKLP----------VPANLYATI 197 Query: 247 VAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLN 306 + K + P ++ + V G + A + ++ M + Sbjct: 198 IHPHVEVQTKDARNILPKQIALSQAVAQWGNV-GGLVAGLLMNDTSLIGRSM-QDHIVEP 255 Query: 307 ALGVGHASLDQLCQVT-AAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCGF 365 A V D + + A L ++G+G ++ + + QA+ GF Sbjct: 256 ARSVLIPGFDDVKKAALDAGALGCSISGSGP-----SIFALSTSQEAAQKIGQAMKK-GF 309 Query: 366 D 366 D Sbjct: 310 D 310 >3GON-A nrPDB Length = 335 Score = 43.8 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 62/348 (17%), Positives = 113/348 (32%), Gaps = 55/348 (15%) Query: 5 VLLVSAPGKVILHGEHAVVH-GKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWD 63 ++ V GK+ GE+A++ G++AL + + + + ++ ++ + + + Sbjct: 1 MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPN 60 Query: 64 VATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQ 123 L+ GD A + L + EG + + + Sbjct: 61 -PDYSLIQETIALMGDFLAVRGQNLRPFSLAI---YGKMEREGKKFGLGSSGSVVVLVVK 116 Query: 124 RTLPSLDIMVW--------SELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIG 175 L ++ V S + G S C+AA + V DR + Sbjct: 117 ALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAA-----EDLVLYQSFDRQKVA 171 Query: 176 SWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLT 235 +W EE+ A ER WG ++ S +K L+ Sbjct: 172 AWLEEE-----NLATVLERD--------------WGFSI-------SQVKPTLECDFLV- 204 Query: 236 NTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLE 295 TK + I LTS + L + + + EQ V Sbjct: 205 -----GWTKEVAVSSHMVQQIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVAS 259 Query: 296 ELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITL 343 +L++ + + L QL + + +K +GAGGG CGI L Sbjct: 260 KLLEGL-----STDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIAL 302 >4RPF-A nrPDB Length = 310 Score = 35.4 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 47/146 (32%), Gaps = 28/146 (19%) Query: 120 CRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPE 179 C++ + +++ +P G+GLGSSA V A+ C Sbjct: 74 CQEMGKEIPVAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCG----------------- 116 Query: 180 EDLKSINKWAYEGERVIHGNPSGV---DNSVSTW-GGALRYQQGKMSSLKRLPALQ---- 231 + L + GE + G SG DN + GG + + + +P Sbjct: 117 QPLDKVTLLGMMGE--LEGRVSGSIHFDNVAPCYLGGMQLILEQEGYISQDVPGFSDWLW 174 Query: 232 -ILLTNTKVPRSTKALVAGVRSRLIK 256 + KV + + + R Sbjct: 175 VMAYPGIKVSTAEARAILPAQYRRQD 200 >3HUL-A nrPDB Length = 298 Score = 34.2 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 45/234 (19%), Positives = 80/234 (34%), Gaps = 41/234 (17%) Query: 131 IMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAY 190 +++ ++PP GLGSS+A V T E + + A Sbjct: 74 LVMTCDIPPARGLGSSSAAVVAGIELANTLAEL---------------NLSKEEKVRIAA 118 Query: 191 EGERVIHGNPSGVDNSVS---TWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALV 247 E E G+P V +V G L + + L AL + ++ S V Sbjct: 119 EIE----GHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESRGV 174 Query: 248 AGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNA 307 P+ + P ++ + + M AA + + E+M+ + H Sbjct: 175 ---------LPDTL-PFKEAV-----QASSIANVMIAAILRNDMTLAGEMMERDLWHEKY 219 Query: 308 LGVGHASLDQLCQVTAAHGLHSK-LTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 L Q+ V G ++ L+GAG + + P K++ + Q L Sbjct: 220 RSQLVPHLAQIRDVAKNQGAYAACLSGAGP---TVLVFAPRNLANKLQTSLQTL 270 >3BEA-A nrPDB Length = 333 Score = 31.5 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 58/185 (31%), Gaps = 20/185 (10%) Query: 135 SELPPGAGLGSSAAYSVCVAAAL----LTACEEVTNPLKDRGSIGSWPEEDLKSINKWAY 190 + L G LG+ A V A A A +V + + E + + ++ Sbjct: 46 NNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSH 105 Query: 191 EGERV---------IHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPR 241 G+ HG P V +G L + + K L+ PA I Sbjct: 106 LGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKSRVLETDPAFAI----ANSTL 161 Query: 242 STKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMN 301 ST+ L+ + + D + G +A + + ++M+ + Sbjct: 162 STRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKI---GDFGLARDIMNDS 218 Query: 302 QHHLN 306 + + Sbjct: 219 NYIVK 223 >4JA0-A nrPDB Length = 425 Score = 30.7 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 35/131 (26%), Gaps = 7/131 (5%) Query: 66 TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRT 125 + L T + + ++Q E + GL + + Sbjct: 295 DVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPP 354 Query: 126 LPSLDIMVWSELPPGAGLG-------SSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWP 178 L +WS L +GLG SAA L K S Sbjct: 355 SDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAAQIIGLQDYLVWGRLRSKQLDMAHSLR 414 Query: 179 EEDLKSINKWA 189 + D K N+ A Sbjct: 415 QADKKLRNQTA 425 >4RBN-A nrPDB Length = 794 Score = 30.3 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 11/83 (13%) Query: 195 VIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRL 254 +I SG+ + +GG L Q S + +T L+A + Sbjct: 669 IIEAMASGLPTFATRYGGPLEIIQNNRSG---------FHIDPNQGAATADLIADFFEKN 719 Query: 255 IKFPEIMAPLLTSIDAISLECER 277 ++ P+ + S A+ R Sbjct: 720 LENPQEWERI--SQGALDRVASR 740 >5EKZ-A nrPDB Length = 294 Score = 29.6 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 30/99 (30%), Gaps = 13/99 (13%) Query: 256 KFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASL 315 + I + L SI E P PE L ++ + + +++ Sbjct: 73 ERSRIFSKLTLSIRLAVKEG---------GPNPENNSSLANIL----ELCRSKNMPKSTI 119 Query: 316 DQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVE 354 + + G++ G G GG + + K Sbjct: 120 ESALKTEKNKGIYLLYEGRGPGGSSLLIEALSNSGPKCH 158 >3UY5-A nrPDB Length = 428 Score = 29.2 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 19/44 (43%) Query: 315 LDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQ 358 L +L H+ G G GG + L++P R + EA + Sbjct: 163 LHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYE 206 >3F4A-A nrPDB Length = 169 Score = 28.8 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 26/70 (37%), Gaps = 7/70 (10%) Query: 202 GVDNSVSTWGGAL-------RYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRL 254 G+D+ T L Q+G ++L+ + + + + K SRL Sbjct: 21 GMDSYSITNVKYLDPTELHRWMQEGHTTTLREPFQVVDVRGSDYMGGHIKDGWHYAYSRL 80 Query: 255 IKFPEIMAPL 264 + PE + L Sbjct: 81 KQDPEYLREL 90 >2YF3-A nrPDB Length = 154 Score = 28.4 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 21/51 (41%) Query: 268 IDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASLDQL 318 +D S E + + A + L +L + + L V + +LDQL Sbjct: 50 LDEESAEVRAEIDHLLARQAAGEALSAGDLAPLAHELADLLYVTYGALDQL 100 >3FS5-A nrPDB Length = 152 Score = 28.4 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 20/50 (40%) Query: 215 RYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMAPL 264 Q+G ++L+ + + + + K SRL + PE + L Sbjct: 20 WMQEGHTTTLREPFQVVDVRGSDYMGGHIKDGWHYAYSRLKQDPEYLREL 69 >4HGV-A nrPDB Length = 495 Score = 28.0 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 17/121 (14%), Positives = 36/121 (29%), Gaps = 17/121 (14%) Query: 245 ALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHH 304 ++ + L + + + + D I + + +++ + + Sbjct: 187 RVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASS--- 243 Query: 305 LNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTGCG 364 + + + L +L Q A G L P KV A+TG G Sbjct: 244 IKRIEMTLPGLCELAQGGTAVGTG--------------LNAPVGFAEKVAEEIAAITGIG 289 Query: 365 F 365 F Sbjct: 290 F 290 >5I0M-A nrPDB Length = 138 Score = 27.6 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 21/51 (41%) Query: 268 IDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASLDQL 318 +D S E + + A + L +L + + L V + +LDQL Sbjct: 38 LDEESAEVRAEIDHLLARQAAGEALSAGDLAPLAHALADLLYVTYGALDQL 88 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.108 0.246 Lambda K H 0.267 0.0331 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,228,903 Number of Sequences: 36641 Number of extensions: 402412 Number of successful extensions: 1213 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1078 Number of HSP's gapped (non-prelim): 92 length of query: 395 length of database: 10,336,785 effective HSP length: 99 effective length of query: 296 effective length of database: 6,709,326 effective search space: 1985960496 effective search space used: 1985960496 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.6 bits)