BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P17169 (609 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4AMV-A nrPDB 1243 0.0 1MOS-A nrPDB 752 0.0 3TBF-A nrPDB 421 e-118 2ZJ4-A nrPDB 293 2e-79 2POC-A nrPDB 284 6e-77 4S1W-A nrPDB 258 4e-69 3HBA-A nrPDB 107 1e-23 2CB0-A nrPDB 107 2e-23 2DF8-A nrPDB 101 1e-21 3FJ1-A nrPDB 94 1e-19 1J5X-A nrPDB 90 3e-18 1AO0-A nrPDB 87 2e-17 3G68-A nrPDB 84 3e-16 1ECF-A nrPDB 69 4e-12 3EUA-A nrPDB 67 2e-11 2AML-A nrPDB 65 7e-11 3KNZ-A nrPDB 60 2e-09 3FKJ-A nrPDB 55 8e-08 3ODP-A nrPDB 51 1e-06 2A3N-A nrPDB 49 9e-06 1CT9-A nrPDB 42 7e-04 3I0Z-A nrPDB 42 7e-04 4LZJ-A nrPDB 41 0.002 3C3J-A nrPDB 41 0.002 4S12-A nrPDB 33 0.36 3MDN-A nrPDB 32 0.84 5UQI-A nrPDB 32 1.0 5XE0-A nrPDB 32 1.0 1X9I-A nrPDB 31 1.6 4Z1Y-A nrPDB 30 2.4 1IYX-A nrPDB 30 2.5 6BFZ-A nrPDB 30 3.3 4MKS-A nrPDB 30 3.8 6BZC-A nrPDB 29 4.7 3L0S-A nrPDB 29 4.7 3ZLH-A nrPDB 29 5.1 1W6T-A nrPDB 29 5.5 5LTM-B nrPDB 29 5.5 2NYF-A nrPDB 28 8.2 3V3W-A nrPDB 28 8.2 >4AMV-A nrPDB Length = 609 Score = 1243 bits (3215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 608/609 (99%), Positives = 609/609 (100%) Query: 1 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE 60 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE Sbjct: 1 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE 60 Query: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV 120 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV Sbjct: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV 120 Query: 121 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV 180 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV Sbjct: 121 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV 180 Query: 181 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ 240 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ Sbjct: 181 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ 240 Query: 241 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA 300 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA Sbjct: 241 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA 300 Query: 301 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL 360 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL Sbjct: 301 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL 360 Query: 361 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL 420 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL Sbjct: 361 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL 420 Query: 421 SRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA 480 S+LKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA Sbjct: 421 SKLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA 480 Query: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR Sbjct: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 Query: 541 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR 600 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR Sbjct: 541 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR 600 Query: 601 NLAKSVTVE 609 NLAKSVTVE Sbjct: 601 NLAKSVTVE 609 >1MOS-A nrPDB Length = 368 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/368 (100%), Positives = 368/368 (100%) Query: 242 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC 301 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC Sbjct: 1 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC 60 Query: 302 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR 361 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR Sbjct: 61 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR 120 Query: 362 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS 421 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS Sbjct: 121 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS 180 Query: 422 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL 481 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL Sbjct: 181 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL 240 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG Sbjct: 241 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 300 Query: 542 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN Sbjct: 301 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 360 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 361 LAKSVTVE 368 >3TBF-A nrPDB Length = 372 Score = 421 bits (1083), Expect = e-118, Method: Compositional matrix adjust. Identities = 207/370 (55%), Positives = 264/370 (71%), Gaps = 4/370 (1%) Query: 243 AGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACG 302 + K Y+HYM KEIYEQP A+ NT+ ++ G++ L A EL K +HI I+ACG Sbjct: 4 SASKDGYKHYMLKEIYEQPEAVSNTILASLADGEISLDSFDKRAKELFEKTKHICIVACG 63 Query: 303 TSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 TSYN+GM ++YW E A +PC VEIASE RYR + V SL +++SQSGETADTL LR Sbjct: 64 TSYNAGMTAKYWIEKYAKVPCSVEIASEIRYRDNVVVDGSLFVSISQSGETADTLESLRK 123 Query: 363 SKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSR 422 SK+ Y+GS+ ICNVP SSLVRESD+A MT AG EIGVASTKAFTTQL L + +++ Sbjct: 124 SKKQNYVGSMCICNVPNSSLVRESDIAFMTKAGVEIGVASTKAFTTQLVALAIFTLVIAK 183 Query: 423 LKG--LDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA 480 LK D I L+ + + + L D I+ ++E FSDK H +FLGRG YPIA Sbjct: 184 LKNSLTDQQIAK-YTEELKNIRALVMGALKLDTEIDQISEYFSDKEHTIFLGRGLYYPIA 242 Query: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 +EGALKLKEISYIHAEAY +GELKHGPLAL+D +MP++ V PN+ELL+K SN++EV AR Sbjct: 243 IEGALKLKEISYIHAEAYPSGELKHGPLALVDKNMPIVAVVPNDELLDKTLSNLQEVHAR 302 Query: 541 GGQLYVFADQDAG-FVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQP 599 GG+L +F D+ V+ DN ++E+ + AP+ +T+PLQLL+YHVA+IKGTDVDQP Sbjct: 303 GGKLILFVDKAVKERVNFDNSIVLELDAGHDFSAPVVFTIPLQLLSYHVAIIKGTDVDQP 362 Query: 600 RNLAKSVTVE 609 RNLAKSVTVE Sbjct: 363 RNLAKSVTVE 372 >2ZJ4-A nrPDB Length = 375 Score = 293 bits (749), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 158/366 (43%), Positives = 230/366 (62%), Gaps = 4/366 (1%) Query: 246 KGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ--VDLSELGPNADELLSKVEHIQILACGT 303 KG + +MQKEI+EQP ++ NT+ GR++ V+L L + E+ + + ++ACGT Sbjct: 12 KGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEI-QRCRRLILIACGT 70 Query: 304 SYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 SY++G+ +R E L +P VE+AS+F R + V R+ + LSQSGETADTL GLR Sbjct: 71 SYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYC 130 Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 KE G L ++ I N GSS+ RE+D + NAG EIGVASTKA+T+Q L+M + Sbjct: 131 KERGAL-TVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDD 189 Query: 424 KGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEG 483 + +I+ GL+ LP I+++LS D I+ LA + + L +GRG Y LEG Sbjct: 190 RISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEG 249 Query: 484 ALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQ 543 ALK+KEI+Y+H+E AGELKHGPLAL+D MPVI++ + K ++ +++V AR G+ Sbjct: 250 ALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGR 309 Query: 544 LYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLA 603 V D++ + I++PH + + I +PLQLLA+H+A+++G DVD PRNLA Sbjct: 310 PVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLA 369 Query: 604 KSVTVE 609 KSVTVE Sbjct: 370 KSVTVE 375 >2POC-A nrPDB Length = 367 Score = 284 bits (727), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 161/368 (43%), Positives = 231/368 (62%), Gaps = 6/368 (1%) Query: 246 KGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQIL--ACGT 303 KG Y+H+MQKEI+EQP++ NT+ GRI ++ LG L + +I+ ACGT Sbjct: 2 KGPYKHFMQKEIFEQPDSAFNTMRGRIDFENCVVT-LGGLKSWLSTIRRCRRIIMIACGT 60 Query: 304 SYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 SY+S + +R FE L IP VE+AS+F R+S V R+ + +SQSGETAD++ L+ Sbjct: 61 SYHSCLATRSIFEELTEIPVSVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYC 120 Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 E G L ++ I N GSS+ R++ + NAG EIGVASTKA+T+Q L+M LS Sbjct: 121 LERGAL-TVGIVNSVGSSMSRQTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSND 179 Query: 424 KGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAED-FSDKHHALFLGRGDQYPIALE 482 +I+ GLQ +P +I+Q+L + +I+ L +D+ L LGRG Q+ ALE Sbjct: 180 SISRKGRHEEIIKGLQKIPEQIKQVLKLENKIKDLCNSSLNDQKSLLLLGRGYQFATALE 239 Query: 483 GALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGG 542 GALK+KEISY+H+E AGELKHG LAL+D D+P+I A + L K+ S IE+V AR G Sbjct: 240 GALKIKEISYMHSEGVLAGELKHGILALVDEDLPIIAFATRDSLFPKVMSAIEQVTARDG 299 Query: 543 QLYVFADQDAGFVSSDNMH-IIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + V ++ +S+D +H +E+P + + + +PLQL++Y +A+ +G DVD PRN Sbjct: 300 RPIVICNEGDAIISNDKVHTTLEVPETVDCLQGLLNVIPLQLISYWLAVNRGIDVDFPRN 359 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 360 LAKSVTVE 367 >4S1W-A nrPDB Length = 358 Score = 258 bits (660), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 150/368 (40%), Positives = 229/368 (62%), Gaps = 12/368 (3%) Query: 244 GDKGIYRHYMQKEIYEQPNAIKNTLTG-RISHGQVDLSELGPNADELLSKVEHIQILACG 302 +KG+Y HYM KEI+EQP ++ + + + G + + + N + + + I ++A G Sbjct: 1 AEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIIND---VKEADRIYVIAAG 57 Query: 303 TSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 TSY++G+V + + E AG+P +V +ASEF Y + L + +SQSGETAD+ A L Sbjct: 58 TSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVE 117 Query: 363 SKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSR 422 + +LG+ SL I NV GS+L RE+D L+ +AG EI VASTKA+T Q+ VL +L +++ Sbjct: 118 TNKLGH-KSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAK 176 Query: 423 LKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDK-HHALFLGRGDQYPIAL 481 G +A I D++ L + + IE ++ +E +A DF + +A F+GR Y ++L Sbjct: 177 EHGREADI--DLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSL 234 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 EGALKLKEISYI AE +A GELKHG +ALI+ PV+ +A + ++ N++EV ARG Sbjct: 235 EGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARG 294 Query: 542 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + + + G + ++I PHV E++ P+ V LQL++Y+ AL + DVD+PRN Sbjct: 295 AHPCIISME--GLEKEGDTYVI--PHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRN 350 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 351 LAKSVTVE 358 >3HBA-A nrPDB Length = 334 Score = 107 bits (268), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 129/254 (50%), Gaps = 12/254 (4%) Query: 292 KVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFR-YRKSAVRRNSLMITLSQS 350 K + + I+ G+S ++G+ ++Y FE A IP S Y K+ L+I +SQS Sbjct: 41 KPKFVMIVGRGSSDHAGVFAKYLFEIEASIPTFAAAPSVASVYGKTLKLAGGLVIVISQS 100 Query: 351 GETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQL 410 G + D LA R++K G +A+ N + + D+ + AG E VA+TK++ L Sbjct: 101 GRSPDILAQARMAKNAGAF-CVALVNDETAPIKDIVDVVIPLRAGEEKAVAATKSYLATL 159 Query: 411 TVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALF 470 + LL + AK ++ +V + +LP ++ + + ++ A +D + + Sbjct: 160 SALLQVAAKWTQ--------NESLVEAVNSLPQALQAAVDAEPQLRA--GSLTDVKNLVV 209 Query: 471 LGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKL 530 LGRG Y ++ E ALKLKE+ IHAEA+++ E HGP+ L++ + ++ V +E Sbjct: 210 LGRGFGYAVSKEIALKLKEVCAIHAEAFSSAEFLHGPVTLVEKKLSILDVCIRDESYGSH 269 Query: 531 KSNIEEVRARGGQL 544 I V+ RG L Sbjct: 270 VEQIANVKQRGANL 283 >2CB0-A nrPDB Length = 333 Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 99/337 (29%), Positives = 161/337 (47%), Gaps = 44/337 (13%) Query: 285 NADELLSKVE-------HIQILACGTSYNSG----MVSRYWFESLAGIPCDVEIASEFRY 333 ADE ++V+ I L CG+S+ MV+ + +PC SEF Y Sbjct: 16 KADESFNQVKDKIRLPRRILYLGCGSSHFLAKLLAMVTNMHGGTGVALPC-----SEFLY 70 Query: 334 RKSA--VRRNSLMITLSQSGETADTLAGLRL--SKELGYLGSLAICNVPGSSLVRESDLA 389 K A + + L++ +S+SGET + L L + +LG + SSL R D + Sbjct: 71 SKEAYPIGKPELVVGISRSGETTEVLLALEKINTPKLG-------ISAYESSLTRACDYS 123 Query: 390 LMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQML 449 L+ E V T +FT L L+ L L+A+ + E+ L Sbjct: 124 LVVPTIEE-SVVMTHSFTAFYFAYLQLLRHSYGLPLLEAT----------EVAKATEKAL 172 Query: 450 SQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLA 509 + I+ + EDF D + +FLG G YP+ALE +LK+KE++ +EAY E++HG A Sbjct: 173 EYENYIKEIVEDF-DFQNVIFLGSGLLYPVALEASLKMKEMAIFWSEAYPTFEVRHGFKA 231 Query: 510 LIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVE 569 + D + V+++A EL E K + E + + ++ + ++ F + IE+P + Sbjct: 232 IADENTLVVLMA--QELFEWHKKLVNEFKGQRARVLLISNSQQEFGQD---YSIEVPRLS 286 Query: 570 EVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSV 606 + PI Y +QLL+Y+ A+ +G + D PR L K V Sbjct: 287 KDATPIPYLPVVQLLSYYKAVARGLNPDNPRFLDKVV 323 >2DF8-A nrPDB Length = 325 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 104/340 (30%), Positives = 160/340 (47%), Gaps = 50/340 (14%) Query: 285 NADELLSKVE-------HIQILACGTSYNS----GMVSRYWFESLAGIPCDVEIASEFRY 333 AD++ +KV+ I L CG+S+ MV+ +PC SEF Y Sbjct: 16 KADKVFNKVKDKISLPNRILYLGCGSSHFLSKLLAMVTNMHGGLGIALPC-----SEFLY 70 Query: 334 RKSA--VRRNSLMITLSQSGETADTLAGLRL--SKELGYLGSLAICNVPGSSLVRESDLA 389 K + L + +S+SGET + L L K+LG SSL R D + Sbjct: 71 SKETYPIGEVELAVGISRSGETTEILLALEKINVKKLG-------ITTRESSLTRMCDYS 123 Query: 390 LMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQML 449 L+ A E V T +FT+ L L+ L L+A + E+ L Sbjct: 124 LVVPAIEE-SVVMTHSFTSFYFAYLQLLRYSYGLPPLNAG----------EISKATEKSL 172 Query: 450 SQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLA 509 ++ I + E F D + +FLG G YP+ALE +LK+KE+S +EAY E++HG A Sbjct: 173 EYERYIREIVESF-DFQNIIFLGSGLLYPVALEASLKMKEMSIFWSEAYPTFEVRHGFKA 231 Query: 510 LID-ADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFAD--QDAGFVSSDNMHIIEMP 566 + D + V++V E EKL ++E + +G ++ V ++ QD G + IE+P Sbjct: 232 IADEKTLVVLMVEEPFEWHEKL---VKEFKNQGAKVLVISNSPQDLG-----QDYSIELP 283 Query: 567 HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSV 606 + + PI Y +QLL+Y+ A+ +G + D PR L K V Sbjct: 284 RLSKDANPIPYLPIVQLLSYYKAVSRGLNPDNPRFLDKVV 323 >3FJ1-A nrPDB Length = 344 Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 101/371 (27%), Positives = 170/371 (45%), Gaps = 45/371 (12%) Query: 247 GIYRHY--MQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTS 304 G+ +H M++EI E P A++ L HG D++ + A L + +A G+S Sbjct: 1 GMTQHITRMRREIDEIPEAVQRLL----DHGAQDVARVA--AVLRLRDPSFVATVARGSS 54 Query: 305 YNSGMVSRYWFESLAGIPCDV---EIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR 361 + Y E L G+P +AS + R R +L + +SQSG++ D +A R Sbjct: 55 DHVCTYLSYAAELLLGLPVASLGPSVASVYDARLRLDR--ALCLAVSQSGKSPDIVAMTR 112 Query: 362 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS 421 + G L +A+ N S L S + +AG E+ VA+TK F T LML+A + Sbjct: 113 NAGRDGAL-CVALTNDAASPLAGVSAHTIDIHAGPELSVAATKTFVTSAVAGLMLLADWA 171 Query: 422 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIE--ALAEDFSDKHHALFLGRGDQYPI 479 GL A++ + LP + L+ RI+ + + LGRG + Sbjct: 172 EDDGLRAALGN--------LP----ETLAAASRIDWPEMRVAIGARPSLFTLGRGTSLAV 219 Query: 480 ALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRA 539 + E ALK KE +HAE+Y++ E+ HGP+++++ PV+ A + L +++ A Sbjct: 220 SNEAALKFKETCQLHAESYSSAEVLHGPVSIVEEGFPVLGFAAGDAAEAPLAEIADQIAA 279 Query: 540 RGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALI------KG 593 +G ++ G V+ + +E V + T PL L+ +++ +G Sbjct: 280 KGATVFA----TTGRVTRARV-------LEHVRSGHALTDPLSLIVSFYSMVEAFASERG 328 Query: 594 TDVDQPRNLAK 604 D D PR+L K Sbjct: 329 IDPDAPRHLNK 339 >1J5X-A nrPDB Length = 342 Score = 89.7 bits (221), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 69/374 (18%) Query: 255 KEIYEQPNAIKNTLTGRISHGQVD--LSELGPN-ADELLSKVEHIQILACGTSYNSGMVS 311 KEI +Q N +K + + + SE+ N DE+L + CG+SYN + Sbjct: 18 KEITDQKNELKKFFENFVLNLEKTEIFSEIQKNLTDEVL-------FVGCGSSYNLALTI 70 Query: 312 RYWFESLAGIPCDVEIASEFRYRK-SAVRRNSLMITLSQSGETADTLAGLRLSKELGYLG 370 Y+FE + I A E ++K + L S++G T + L + K+ + Sbjct: 71 SYYFERVLKIRTKAIPAGEVAFQKIPDLEERGLAFLFSRTGNTTEVLLANDVLKKRNH-R 129 Query: 371 SLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL--------SR 422 ++ I S L +ESDL L+ E + TK+F+ L L+ L K+ S Sbjct: 130 TIGITIEEESRLAKESDLPLVFPVREE-AIVMTKSFSMILLSLMFLADKIAGNSTERFSE 188 Query: 423 LKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALE 482 L G DI K IE + D + H +FLG + + ++LE Sbjct: 189 LVGYSPEF-FDISW----------------KVIEKI--DLKEHDHFVFLGMSEFFGVSLE 229 Query: 483 GALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIV--VAPNNELLEKLKSNIEEVRA- 539 ALK E+S +EAY+ E +HGP AL+ V + V+ +E ++L+ +E + A Sbjct: 230 SALKCIEMSLTFSEAYSTLEYRHGPKALVKKGTLVFMQKVSGMDEQEKRLRKELESLGAT 289 Query: 540 -----RGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGT 594 GG + V D + F+ TVP Q+L Y A+ +G Sbjct: 290 VLEVGEGGDIPVSNDWKSAFLR---------------------TVPAQILGYQKAISRGI 328 Query: 595 DVDQPRNLAKSVTV 608 D+P +L K+V + Sbjct: 329 SPDKPPHLEKTVVL 342 >1AO0-A nrPDB Length = 459 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 99/206 (48%), Gaps = 13/206 (6%) Query: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 61 CG+ G + +I GL L++RG + AG+ D E +T + G + + Q E Sbjct: 1 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGE-KLTAHKGQGLITEVFQNGEL 59 Query: 62 HPLHGGTGIAHTRWATHGEPSEVNAHP-----HVSEHIVVVHNGIIENHEPLREELKARG 116 + G I H R+AT G N P + + + HNG + N L+++L+ +G Sbjct: 60 SKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQG 119 Query: 117 YTFVSETDTEVIAHLVNWELKQGG--TLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAAR 174 F + +DTEV+AHL+ K+ G TL++ + ++ L+GAY +IM L Sbjct: 120 SIFQTSSDTEVLAHLI----KRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPN 175 Query: 175 SGSPLVIGLGMGENFIASDQLALLPV 200 PL IG+ MG+ ++ + + V Sbjct: 176 GLRPLSIGM-MGDAYVVASETCAFDV 200 >3G68-A nrPDB Length = 352 Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 90/343 (26%), Positives = 157/343 (45%), Gaps = 35/343 (10%) Query: 277 VDLSELGPNADELLSKVEH-----IQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEF 331 V + E+ NAD L ++V+ I I GTSY+SG+ + + ++L I DV F Sbjct: 13 VRMREIISNADSLFNEVKRTNLKKIIITGSGTSYHSGVQVQPYLQNLLDI--DVVKMYPF 70 Query: 332 RYRKSAVR---RNSLMITLSQSGETADTLAGLRLSKELGY-LGSLAICNVPGSSLVRE-S 386 + + N+L++ +SQ G + T ++L+++ G + S+A C ++L+ E S Sbjct: 71 MITEDTFKFDNENTLVVGVSQGGSSYSTYNAMKLAEDKGCKIASMAGCK---NALIDEIS 127 Query: 387 DLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHD--IVHGLQALPSR 444 D L N G E A TK + L++L +++R KG+ +S +++ I L A+ +R Sbjct: 128 DYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQIAREKGIISSEKYNEEINKILDAI-NR 186 Query: 445 IEQMLSQDKR-IEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGEL 503 E + K+ IE E + +G D Y LE ALKL E I Y E Sbjct: 187 FEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDIYGDTLEAALKLLETMRIPVTGYEFEEF 246 Query: 504 KHGPLALIDADMPVIVVAPNNE-----LLEKLKSNIEEVRARGGQLYVFADQDAGFVSSD 558 HG I++D + ++ E +++ L E V A G + + D Sbjct: 247 IHGIYNAINSDSTIFILDTGKEPRVTKMIDVLSGWTENVFAIGRDV---TENDKNL---- 299 Query: 559 NMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + I + P+ + + VP+QL+ + ++G D P++ Sbjct: 300 KIDITDNPYYQ----TFNFIVPIQLICGEIPTLRGVDPSVPKD 338 >1ECF-A nrPDB Length = 504 Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 63/214 (29%), Positives = 96/214 (44%), Gaps = 19/214 (8%) Query: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRL-GKVQMLAQAAE 60 CGIVG V + + + L L++RG D+AG+ +DA + RLR+ G V + +A Sbjct: 1 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDA-NNCFRLRKANGLVSDVFEARH 59 Query: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEH---IVVVHNGIIENHEPLREELKARGY 117 L G GI H R+ T G S A P I + HNG + N LR++L Sbjct: 60 MQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKR 119 Query: 118 TFVSET-DTEVIAHLVNWELK-------QGGTLREAVLRAIPQLRGAYGTVIMDSRHPDT 169 ++ T D+E++ ++ EL + + A+ +RGAY V M H Sbjct: 120 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 179 Query: 170 LLAARSG-SPLVIGL-----GMGENFIASDQLAL 197 +G PLV+G E +AS+ +AL Sbjct: 180 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVAL 213 >3EUA-A nrPDB Length = 329 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 109/236 (46%), Gaps = 19/236 (8%) Query: 293 VEHIQILACGTSYNSGMVSRYWFESLA-GIPCDVEIASEFRYRKSA-VRRNSLMITLSQS 350 ++H+ +ACG S S+Y F+ + I D+ A+EF R + SL+I S S Sbjct: 25 IDHVFFVACGGSSAIMYPSKYVFDRESKSINSDLYSANEFIQRNPVQLGEKSLVILCSHS 84 Query: 351 GETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQL 410 G T +T+ ++ G L ++A+ P S L +E+ + G E A T Sbjct: 85 GNTPETVKAAAFARGKGAL-TIAMTFKPESPLAQEAQYVAQYDWGDE-----ALAINTNY 138 Query: 411 TVLLMLVAKLSRLKGLDASIEHD-IVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHA- 468 VL +V L+ L+ + + + + GL L + E+ L Q+ A+ F+ H Sbjct: 139 GVLYQIV--FGTLQVLENNTKFEQAIEGLDQLQAVYEKALKQEADN---AKQFAKAHEKE 193 Query: 469 ---LFLGRGDQYPIALEGALK-LKEISYIHAEAYAAGELKHGPLALIDADMPVIVV 520 + G Y +A ++ L E+ +IH+ A AGE HGP +ID +P I++ Sbjct: 194 SIIYTMASGANYGVAYSYSICILMEMQWIHSHAIHAGEYFHGPFEIIDESVPFIIL 249 >2AML-A nrPDB Length = 373 Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 73/332 (21%), Positives = 145/332 (43%), Gaps = 16/332 (4%) Query: 276 QVDLSELGPNADELLSKVEH----IQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEF 331 +V L++ NA++L S V++ ILA G+S N+ ++Y+ E+LA + +E Sbjct: 29 RVILADFQTNAEKLESLVKNGAKEWLILATGSSLNAAQSAKYYIENLADVRITIEEPFNH 88 Query: 332 RYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALM 391 Y + L+I +SQSG++ T++ L K+ + +A+ + S + +D+ L Sbjct: 89 LYYEKLSSHLDLVIGISQSGQSTSTISALERVKKEASVPVVALTSDVTSEIAEFADITLD 148 Query: 392 TNAGTEIGVASTKAFT-TQLTVLLMLVAKLSRLKGLDASIEHDIV----HGLQALPSRIE 446 +G E TK FT T LT++L + + +D + ++ + + A+P+ I Sbjct: 149 IGSGKERVGYVTKGFTATVLTLMLTGLHFAYKTVQIDETRFNNEISAFSRAIDAIPATIA 208 Query: 447 QMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHG 506 + + E E+F+ +G G E K E + ++ HG Sbjct: 209 E---TEAFYERWQEEFATAPKFTAIGYGPTVGTCKEFETKFSETVRVPSQGLDLEAFMHG 265 Query: 507 PLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP 566 P ++ + + + + E+L +R + F D+ ++ Sbjct: 266 PYLEVNPQHRIFFLETASAVTERLVL----LRDYESKYTPFTYTVKFGKGEDDRTLVIPT 321 Query: 567 HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQ 598 ++E AP +P Q+LA+H+A +KG + + Sbjct: 322 DLDEYQAPFLMILPFQILAHHIAELKGNKLTE 353 >3KNZ-A nrPDB Length = 366 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 67/314 (21%), Positives = 134/314 (42%), Gaps = 15/314 (4%) Query: 293 VEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGE 352 V I + GTSY+ + +R + + +P DV A +L++ +SQ G Sbjct: 50 VTRIILTGSGTSYHGALTARTFMQRWCALPVDVCWPFMLDDETLARSGKALVVGISQGGG 109 Query: 353 TADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAF-TTQLT 411 + TLA + ++ +G++ + ++ V +++ R +D L G E A TK + T L Sbjct: 110 SLSTLAAMERARNVGHI-TASMAGVAPATIDRAADYILTVPCGEETAGAKTKGYHCTVLN 168 Query: 412 VLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDK---RIEALAEDFSDKHHA 468 ++L+ +A + + LD ++ ++ + + +++ + + ALA D Sbjct: 169 LMLLALAVAGQQQRLDGEQRRSLLLRMEKTFNHLPALVTASQAWAQTNALA--LRDSADI 226 Query: 469 LFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLE 528 G + EGALK+ E Y E HG +A +I++ P + + Sbjct: 227 RLTGPATLFGTVQEGALKMLETLRCPVSGYEFEEFIHGIYNAFNAQSALIMLDPQPDARQ 286 Query: 529 KLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIF-YTVPLQLLAYH 587 + I + +Y Q V ++ ++ + P V + +F Y +PLQ+L Sbjct: 287 DRLAQI--LGEWTPSIYRIGPQ----VENNGLN-LNFPFVNDEDFAVFEYIIPLQMLCAI 339 Query: 588 VALIKGTDVDQPRN 601 + KG + P++ Sbjct: 340 LPPQKGINPAIPKD 353 >3FKJ-A nrPDB Length = 347 Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 55/240 (22%), Positives = 105/240 (43%), Gaps = 22/240 (9%) Query: 292 KVEHIQILACGTSYNSGMVSRYWFESLAG-IPCDVEIASEFRY-RKSAVRRNSLMITLSQ 349 +E + + CG S +Y+ + A + ++EF + A+ +NS++I SQ Sbjct: 39 NIERVWFVGCGGSLTGFWPGKYFLDCEASKLAVGYITSNEFVHATPKALGKNSVVILASQ 98 Query: 350 SGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLAL---MTNAGTEIGVASTKAF 406 G TA+T+A R+++E G ++ + P + L SD + + A KA Sbjct: 99 QGNTAETVAAARVAREKG-AATIGLVYQPDTPLCEYSDYIIEYQWARYPETVDPAQQKA- 156 Query: 407 TTQLTVLLMLVAKLSRLKGLDASIE-----HDIVHGLQALPSRIEQMLSQDKRIEALAED 461 L + L ++A+ D + D+VHG Q + + +D + A + Sbjct: 157 AYSLWLALEILAQTEGYAQYDELVSAFGRFSDVVHGAQ-------RQVQEDA--QRFAAE 207 Query: 462 FSDKHHALFLGRGDQYPIA-LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVV 520 + D+ +G G + A E L E+ +I++ + +GE HGP + + P I++ Sbjct: 208 WKDEKVVYMMGSGPSFGAAHQESICILLEMQWINSASIHSGEYFHGPFEITEPGTPFILL 267 >3ODP-A nrPDB Length = 393 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 64/283 (22%), Positives = 132/283 (46%), Gaps = 43/283 (15%) Query: 342 SLMITLSQSGETADTLAGLRLSKEL-GYLGSLAI-CNVPGSSLVR-----ESDLALMTNA 394 +L+I+ ++SG + ++ A + L++++ + L I CN G + S L LM Sbjct: 110 TLLISCARSGNSPESTAAVTLAEKIVDDISHLIITCNSEGKLALHAKRNYNSFLLLMPEE 169 Query: 395 GTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKR 454 + G A T +F+T L L L+ L +L+ + IE + G + L + +E M K+ Sbjct: 170 SNDKGFAMTGSFSTMLLSCL-LIFNLDKLESIGKQIESISMQGEKVLVNNVELM----KK 224 Query: 455 IEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGEL----------K 504 I + E F ++LG + + +A E ALK+ E++ AG++ + Sbjct: 225 I--VGEKF---KRTVYLGAANAFGLAKESALKVLELT--------AGKIATLYDTPLGFR 271 Query: 505 HGPLALIDADMPVIVVAPNNELLEKLKSN-IEEVRARGGQLYVFA--DQDAGFVSSDNMH 561 HGP ++ID + +++ N+ + + + ++EV ++ G V A + + + ++ + Sbjct: 272 HGPKSIIDDETLIVIFFSNDTYAREYEYDLLKEVYSQNGNHKVLAISEYEDKLIEDNSDY 331 Query: 562 II-----EMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQP 599 I E + ++ + Y + Q+ A+ ++ G D P Sbjct: 332 FIAINKEEQEYEDDSFLSLDYLLNAQMYAFINSMELGIGPDNP 374 >2A3N-A nrPDB Length = 355 Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 44/208 (21%), Positives = 97/208 (46%), Gaps = 13/208 (6%) Query: 316 ESLAGIPCDVEIASEFRYR-KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAI 374 + L +P VE A+E ++ + ++S++ITLS+SG+T +++A K G Sbjct: 77 KELTTLPVYVEQAAELIHKGNKRLNKDSVVITLSKSGDTKESVAIAEWCKAQG------- 129 Query: 375 CNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDI 434 + ++ + +D L A I + + +L L ++ AS + Sbjct: 130 --IRVVAITKNADSPLAQAATWHIPMRHKNGVEYEYMLLYWLFFRVLSRNNEFASYDR-F 186 Query: 435 VHGLQALPSRIEQMLSQ-DKRIEALAEDFSDKHHALFLGRGDQY-PIALEGALKLKEISY 492 L+ LP+ + + + D + +A+A + + + +++G + + + L L+E+ + Sbjct: 187 ASQLEILPANLLKAKQKFDPQADAIASRYHNSDYMMWVGGAEMWGEVYLFSMCILEEMQW 246 Query: 493 IHAEAYAAGELKHGPLALIDADMPVIVV 520 ++ E HG L L++ D+P+I+V Sbjct: 247 KRTRPVSSAEFFHGALELLEKDVPLILV 274 >1CT9-A nrPDB Length = 553 Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 30/165 (18%) Query: 93 HIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQ 152 H++ V NG I NH+ LR E R Y F + +D EVI L +E + Sbjct: 69 HVLAV-NGEIYNHQALRAEYGDR-YQFQTGSDCEVILAL----------YQEKGPEFLDD 116 Query: 153 LRGAYGTVIMDSRHPDTLLAARSG---SPLVIGLG-MGENFIASDQLALLPVTR------ 202 L+G + + DS D L R PL +G G+ ++AS+ AL+PV R Sbjct: 117 LQGMFAFALYDSEK-DAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFP 175 Query: 203 --RFIFLEEGDIAEITRRSVNIFDKTGAEVK-----RQDIESNLQ 240 +++ ++G+I R +D V RQ +E +++ Sbjct: 176 AGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVK 220 >3I0Z-A nrPDB Length = 389 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 68/308 (22%), Positives = 136/308 (44%), Gaps = 40/308 (12%) Query: 255 KEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACG---TSYNSGMVS 311 +EIY+QP+ + Q E+ E+ K ++I+++ G ++Y + Sbjct: 20 REIYQQPDVWREAF----EFYQAKREEIAAFLQEIADKHDYIKVILTGAGTSAYVGDTLL 75 Query: 312 RYWFE-------SLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSK 364 Y+ E + I +A+ Y K V +++++ ++SG + ++LA + L+K Sbjct: 76 PYFKEVYDERKWNFNAIATTDIVANPATYLKKDVA--TVLVSFARSGNSPESLATVDLAK 133 Query: 365 EL-GYLGSLAI-CNVPGSSLVR----ESDLALMTNA-GTEIGVASTKAFTTQ-LTVLLML 416 L L + I C G ++ + +L L+ A + G A T +FT+ LT LL+ Sbjct: 134 SLVDELYQVTITCAADGKLALQAHGDDRNLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVF 193 Query: 417 VAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQ 476 +K + + S ++L + + ++ L + D + ++LG G Sbjct: 194 DPTEFAVKS----------ERFEVVSSLARKVLDKAEDVKELVD--LDFNRVIYLGAGPF 241 Query: 477 YPIALEGALKLKEISYIH-AEAYAAGE-LKHGPLALIDADMPVIVVAPNNELLEKLKSNI 534 + +A E LK+ E++ A Y + +HGP +LI+ + V+V + K ++ Sbjct: 242 FGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSLINDNTVVLVFGTTTDYTRKY--DL 299 Query: 535 EEVRARGG 542 + VR G Sbjct: 300 DLVREVAG 307 >4LZJ-A nrPDB Length = 303 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/79 (35%), Positives = 47/79 (59%), Gaps = 3/79 (3%) Query: 340 RNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEI- 398 +N +++ ++ SG T +AGL+ +K LG L +++I + P S + +D+A+ T G EI Sbjct: 137 KNDVLVGIAASGRTPYVIAGLQYAKSLGAL-TISIASNPKSEMAEIADIAIETIVGPEIL 195 Query: 399 -GVASTKAFTTQLTVLLML 416 G + K+ T Q VL ML Sbjct: 196 TGSSRLKSGTAQKMVLNML 214 >3C3J-A nrPDB Length = 384 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 83/375 (22%), Positives = 157/375 (41%), Gaps = 52/375 (13%) Query: 252 YMQKEIYEQPNAIKNTLTGRISHGQVD-LSELGPNADELLSKVEHIQIL--ACGTSYNSG 308 + ++EI QP A +LT +D L N E L + E+++I+ GTS G Sbjct: 15 WTEEEIRHQPRAWIRSLT------NIDALRSALNNFLEPLLRKENLRIILTGAGTSAFIG 68 Query: 309 MVSRYWFES-----LAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 + W S + +P + + Y A L+I+ +SG + +++A + L+ Sbjct: 69 DIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA--HPLLLISFGRSGNSPESVAAVELA 126 Query: 364 KEL-GYLGSLAI-CNVPGS----SLVRESDLALMTNAGT-EIGVASTKAFTTQLTVLLML 416 + L I CN G+ ++ ++ AL+ A T + G A T + TT + L + Sbjct: 127 NQFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMMASCLAV 186 Query: 417 VAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQ 476 A + +++ D+ R + +L+ ++ ++LG G Sbjct: 187 FAP----ETINSQTFRDVA-------DRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGL 235 Query: 477 YPIALEGALKLKEISYIHAEAY--AAGELKHGPLALIDADMPVIVVAPNN--------EL 526 A E ALK+ E++ A+ + +HGP +L+D + V+V ++ +L Sbjct: 236 QGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDL 295 Query: 527 LEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP--HVEEVIAPIFYTVPLQLL 584 L +L+ + + +R + A + + V++ HII P H +V + + Q Sbjct: 296 LAELRRDNQAMR-----VIAIAAESSDIVAA-GPHIILPPSRHFIDVEQAFCFLMYAQTF 349 Query: 585 AYHVALIKGTDVDQP 599 A +L G D P Sbjct: 350 ALMQSLHMGNTPDTP 364 >4S12-A nrPDB Length = 298 Score = 33.1 bits (74), Expect = 0.36, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 343 LMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVAS 402 +++ L+ SG T + LR +++LG + CN P S + +E+ +A+ G E S Sbjct: 137 MVVGLAASGRTPYVIGALRFARQLGCPTAAISCN-PDSPIAQEALVAISPVVGPEALTGS 195 Query: 403 T--KAFTTQLTVLLML 416 T K+ T Q VL ML Sbjct: 196 TRMKSGTAQKLVLNML 211 >3MDN-A nrPDB Length = 274 Score = 32.0 bits (71), Expect = 0.84, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 13/109 (11%) Query: 62 HPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREE----LKARGY 117 H + G ++H R +T S N HP + +HNG + E R++ + Y Sbjct: 77 HHVRSGLFLSHVRASTGSCISRNNCHPFAARRWCFMHNGQVGGFEAFRKQADMAIADEFY 136 Query: 118 TF-VSETDTEVIAHLVNWELKQG--GTLREAVLRAIPQLRG---AYGTV 160 T+ TD+EV+ L L +G A+ RAI +L G A+GT Sbjct: 137 TYRKGSTDSEVLFLLA---LSEGLEHDPHGALARAIARLEGLSRAHGTT 182 >5UQI-A nrPDB Length = 198 Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 6/91 (6%) Query: 338 VRRNSLMITLSQSGETADTLAGLRLSKELG-YLGSLAICNVPGSSLVRESDLALMTNAGT 396 V ++ ++I +S SGETA+ LA L K++G YL ++ SSL DL++ + Sbjct: 88 VAKDDVVILISNSGETAEILATLPSLKKMGNYL--ISFTRSHHSSLAISCDLSVEIPVKS 145 Query: 397 E---IGVASTKAFTTQLTVLLMLVAKLSRLK 424 E +G+A + + T L V + LS LK Sbjct: 146 EADNLGLAPSCSSTVVLVVGDAVALALSELK 176 >5XE0-A nrPDB Length = 468 Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust. Identities = 32/143 (22%), Positives = 58/143 (40%), Gaps = 17/143 (11%) Query: 365 ELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLK 424 +LGY + + S+ D + N G G + T F T + +++ + K Sbjct: 252 KLGYTHQTSFIDYLCHSVHLYKDRKYIVNGGMPSGSSGTSIFNTMINNIIIRTLLIRVYK 311 Query: 425 GLDASIEHDIVHG---LQALPSRIEQ-MLSQDKRIEALAEDFSDK---------HHALFL 471 G+D I +G + + P +I+ +L++ + L +DK + FL Sbjct: 312 GIDLDQFKMIAYGDDVIASYPHKIDPALLAEAGKHYGLVMTPADKGTSFVDTNWENVTFL 371 Query: 472 GR----GDQYPIALEGALKLKEI 490 R DQYP + + +KEI Sbjct: 372 KRYFRADDQYPFLIHPVMPMKEI 394 >1X9I-A nrPDB Length = 302 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 59/158 (37%), Gaps = 37/158 (23%) Query: 340 RNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIG 399 R+ L+I +S SG T +TL + +K +P ++ LA M + Sbjct: 79 RDGLLIAVSYSGNTIETLYTVEYAKR---------RRIPAVAITTGGRLAQMGVPTVIVP 129 Query: 400 VASTK--AFTTQLTVLLMLVAKLSRLKGLDASIE-----------HDIVHGLQALPS--- 443 AS A LT L +VAK+ G+D I H +V Q P+ Sbjct: 130 KASAPRAALPQLLTAALHVVAKVY---GIDVKIPEGLEPPNEALIHKLVEEFQKRPTIIA 186 Query: 444 ---------RIEQMLSQDKRIEALAEDFSDKHHALFLG 472 R++ +++ +IE E + HH G Sbjct: 187 AESMRGVAYRVKNEFNENAKIEPSVEILPEAHHNWIEG 224 >4Z1Y-A nrPDB Length = 426 Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSL-VRESDLALMTNAG 395 NS++I L+Q G +TL+ ++L++ G+ + + + G S V +DL + TNAG Sbjct: 333 NSILIKLNQIGSLTETLSAIQLAQRSGW--TAVVSHRSGESEDVTIADLVVATNAG 386 >1IYX-A nrPDB Length = 432 Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRE-SDLALMTNAG 395 NS++I ++Q G +T + ++KE GY + + + G + SD+A+ TNAG Sbjct: 335 NSILIKVNQIGTLTETFEAIEMAKEAGY--TAVVSHRSGETEDSTISDIAVATNAG 388 >6BFZ-A nrPDB Length = 449 Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSL-VRESDLALMTNAG 395 NS++I +Q G +TLA ++++K+ GY + I + G + +DLA+ T AG Sbjct: 354 NSILIKFNQIGSLTETLAAIKMAKDAGY--TAVISHRSGETEDATIADLAVGTAAG 407 >4MKS-A nrPDB Length = 440 Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSL-VRESDLALMTNAG 395 NS++I L+Q G +T + ++KE GY + + + G + +DL + TNAG Sbjct: 334 NSILIKLNQIGTLTETFEAIEMAKEAGY--TAVVSHRSGETEDTTIADLVVATNAG 387 >6BZC-A nrPDB Length = 555 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 6/78 (7%) Query: 369 LGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDA 428 L + + NV G+ + +++ N T + + ++K FTTQ T+ L AK LK A Sbjct: 184 LNTHFVSNVDGNHI---AEVVKNLNPETTLFIIASKTFTTQETMTNALSAKEWFLK---A 237 Query: 429 SIEHDIVHGLQALPSRIE 446 E D+ AL + IE Sbjct: 238 GKEEDVAKHFVALSTNIE 255 >3L0S-A nrPDB Length = 223 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Query: 522 PNNELLEKLKSNIEEVRARGGQLYVFA-DQDAGFVSSDNMHIIEMPHVEEVIAPIFY 577 PNN +E +K N + R GG L A DQD G ++ H I V+ +A +Y Sbjct: 136 PNNIFIEAIKPNGDVCRVCGGALSARADDQDEGAINK--RHDIYYNTVDGTLAAAYY 190 >3ZLH-A nrPDB Length = 455 Score = 29.3 bits (64), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRE-SDLALMTNAG 395 NS++I ++Q G +T + ++KE GY + + + G + +D+A+ TNAG Sbjct: 359 NSILIKVNQIGTLTETFEAIEMAKEAGY--TAVVSHRSGETEDSTIADIAVATNAG 412 >1W6T-A nrPDB Length = 444 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 3/56 (5%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRE-SDLALMTNAG 395 NS++I ++Q G +T + ++KE GY + + + G + +D+A+ TNAG Sbjct: 348 NSILIKVNQIGTLTETFEAIEMAKEAGY--TAVVSHRSGETEDSTIADIAVATNAG 401 >5LTM-B nrPDB Length = 539 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQ-LTVLLMLVAKLS- 421 KE+ +L N+ +L+ + LA+M G+A+ + TQ LT + M V L Sbjct: 171 KEMDAPTALRQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDI 230 Query: 422 -RLKGLDASIEHDIVHGLQALPSRI---EQMLSQDKRIEALAEDFSDKH 466 L G + S H +H + P ++ +QM+S + + ++ KH Sbjct: 231 QALNGTNQSF-HPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKH 278 >2NYF-A nrPDB Length = 569 Score = 28.5 bits (62), Expect = 8.2, Method: Compositional matrix adjust. Identities = 23/108 (21%), Positives = 48/108 (44%), Gaps = 5/108 (4%) Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 KE+ + +L+ +P L + LA+M G+A+ + ++ + L + + Sbjct: 195 KEMDAVTALSRLGLPKLQLQPKEGLAMMNGTSVMTGIAANCVYDAKVLLALTMGVHALAI 254 Query: 424 KGLDASIE--HDIVHGLQALPSRI---EQMLSQDKRIEALAEDFSDKH 466 +GL + + H +H + P ++ +QM S K + E+ KH Sbjct: 255 QGLYGTNQSFHPFIHQCKPHPGQLWTADQMFSLLKDSSLVREELDGKH 302 >3V3W-A nrPDB Length = 424 Score = 28.5 bits (62), Expect = 8.2, Method: Compositional matrix adjust. Identities = 22/105 (20%), Positives = 43/105 (40%), Gaps = 2/105 (1%) Query: 339 RRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEI 398 R L T + + TL +R +K+ GY C +PG + + + Sbjct: 136 RERILSYTHANGKDLDSTLEAVRKAKDKGYKAIRVQCGIPGIAKTYGVSTNTKSYEPADA 195 Query: 399 GVASTKAFTTQ--LTVLLMLVAKLSRLKGLDASIEHDIVHGLQAL 441 + S + ++T+ L + + A + + G D + HD+ H L + Sbjct: 196 DLPSVEVWSTEKYLNYIPDVFAAVRKEFGPDIHLLHDVHHRLTPI 240 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4AMV-A nrPDB 853 0.0 1MOS-A nrPDB 480 e-135 3TBF-A nrPDB 400 e-112 2ZJ4-A nrPDB 393 e-109 2POC-A nrPDB 376 e-104 4S1W-A nrPDB 334 5e-92 1AO0-A nrPDB 256 2e-68 2DF8-A nrPDB 256 2e-68 2CB0-A nrPDB 256 3e-68 2AML-A nrPDB 252 4e-67 3KNZ-A nrPDB 250 1e-66 3G68-A nrPDB 247 9e-66 1ECF-A nrPDB 247 1e-65 1J5X-A nrPDB 246 2e-65 3FJ1-A nrPDB 244 7e-65 3C3J-A nrPDB 240 2e-63 3HBA-A nrPDB 233 2e-61 3ODP-A nrPDB 215 4e-56 3I0Z-A nrPDB 208 4e-54 3FKJ-A nrPDB 193 2e-49 3EUA-A nrPDB 193 2e-49 2A3N-A nrPDB 171 9e-43 1CT9-A nrPDB 170 1e-42 4LZJ-A nrPDB 70 2e-12 Sequences not found previously or not previously below threshold: 4S12-A nrPDB 62 7e-10 3FXA-A nrPDB 57 3e-08 5UQI-A nrPDB 54 2e-07 1VIM-A nrPDB 53 4e-07 1TK9-A nrPDB 49 6e-06 3ETN-A nrPDB 49 7e-06 1M3S-A nrPDB 46 4e-05 5LU5-A nrPDB 45 1e-04 3MDN-A nrPDB 44 1e-04 1X9I-A nrPDB 44 3e-04 2I2W-A nrPDB 43 4e-04 5I01-A nrPDB 34 0.17 2Q8N-A nrPDB 34 0.24 6BFZ-A nrPDB 34 0.25 3TQI-A nrPDB 31 1.9 3O85-A nrPDB 30 3.6 1ZZG-A nrPDB 30 4.0 >4AMV-A nrPDB Length = 609 Score = 853 bits (2203), Expect = 0.0, Method: Composition-based stats. Identities = 608/609 (99%), Positives = 609/609 (100%) Query: 1 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE 60 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE Sbjct: 1 MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE 60 Query: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV 120 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV Sbjct: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV 120 Query: 121 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV 180 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV Sbjct: 121 SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV 180 Query: 181 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ 240 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ Sbjct: 181 IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ 240 Query: 241 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA 300 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA Sbjct: 241 YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA 300 Query: 301 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL 360 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL Sbjct: 301 CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL 360 Query: 361 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL 420 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL Sbjct: 361 RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL 420 Query: 421 SRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA 480 S+LKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA Sbjct: 421 SKLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA 480 Query: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR Sbjct: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 Query: 541 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR 600 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR Sbjct: 541 GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR 600 Query: 601 NLAKSVTVE 609 NLAKSVTVE Sbjct: 601 NLAKSVTVE 609 >1MOS-A nrPDB Length = 368 Score = 480 bits (1234), Expect = e-135, Method: Composition-based stats. Identities = 368/368 (100%), Positives = 368/368 (100%) Query: 242 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC 301 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC Sbjct: 1 DAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILAC 60 Query: 302 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR 361 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR Sbjct: 61 GTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLR 120 Query: 362 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS 421 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS Sbjct: 121 LSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLS 180 Query: 422 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL 481 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL Sbjct: 181 RLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL 240 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG Sbjct: 241 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 300 Query: 542 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN Sbjct: 301 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 360 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 361 LAKSVTVE 368 >3TBF-A nrPDB Length = 372 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 206/369 (55%), Positives = 263/369 (71%), Gaps = 2/369 (0%) Query: 243 AGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACG 302 + K Y+HYM KEIYEQP A+ NT+ ++ G++ L A EL K +HI I+ACG Sbjct: 4 SASKDGYKHYMLKEIYEQPEAVSNTILASLADGEISLDSFDKRAKELFEKTKHICIVACG 63 Query: 303 TSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 TSYN+GM ++YW E A +PC VEIASE RYR + V SL +++SQSGETADTL LR Sbjct: 64 TSYNAGMTAKYWIEKYAKVPCSVEIASEIRYRDNVVVDGSLFVSISQSGETADTLESLRK 123 Query: 363 SKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSR 422 SK+ Y+GS+ ICNVP SSLVRESD+A MT AG EIGVASTKAFTTQL L + +++ Sbjct: 124 SKKQNYVGSMCICNVPNSSLVRESDIAFMTKAGVEIGVASTKAFTTQLVALAIFTLVIAK 183 Query: 423 LKG-LDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIAL 481 LK L L+ + + + L D I+ ++E FSDK H +FLGRG YPIA+ Sbjct: 184 LKNSLTDQQIAKYTEELKNIRALVMGALKLDTEIDQISEYFSDKEHTIFLGRGLYYPIAI 243 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 EGALKLKEISYIHAEAY +GELKHGPLAL+D +MP++ V PN+ELL+K SN++EV ARG Sbjct: 244 EGALKLKEISYIHAEAYPSGELKHGPLALVDKNMPIVAVVPNDELLDKTLSNLQEVHARG 303 Query: 542 GQLYVFADQD-AGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR 600 G+L +F D+ V+ DN ++E+ + AP+ +T+PLQLL+YHVA+IKGTDVDQPR Sbjct: 304 GKLILFVDKAVKERVNFDNSIVLELDAGHDFSAPVVFTIPLQLLSYHVAIIKGTDVDQPR 363 Query: 601 NLAKSVTVE 609 NLAKSVTVE Sbjct: 364 NLAKSVTVE 372 >2ZJ4-A nrPDB Length = 375 Score = 393 bits (1009), Expect = e-109, Method: Composition-based stats. Identities = 158/366 (43%), Positives = 230/366 (62%), Gaps = 4/366 (1%) Query: 246 KGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ--VDLSELGPNADELLSKVEHIQILACGT 303 KG + +MQKEI+EQP ++ NT+ GR++ V+L L + E+ + + ++ACGT Sbjct: 12 KGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEI-QRCRRLILIACGT 70 Query: 304 SYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 SY++G+ +R E L +P VE+AS+F R + V R+ + LSQSGETADTL GLR Sbjct: 71 SYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYC 130 Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 KE G L ++ I N GSS+ RE+D + NAG EIGVASTKA+T+Q L+M + Sbjct: 131 KERGAL-TVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDD 189 Query: 424 KGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEG 483 + +I+ GL+ LP I+++LS D I+ LA + + L +GRG Y LEG Sbjct: 190 RISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEG 249 Query: 484 ALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQ 543 ALK+KEI+Y+H+E AGELKHGPLAL+D MPVI++ + K ++ +++V AR G+ Sbjct: 250 ALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGR 309 Query: 544 LYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLA 603 V D++ + I++PH + + I +PLQLLA+H+A+++G DVD PRNLA Sbjct: 310 PVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLA 369 Query: 604 KSVTVE 609 KSVTVE Sbjct: 370 KSVTVE 375 >2POC-A nrPDB Length = 367 Score = 376 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 161/368 (43%), Positives = 231/368 (62%), Gaps = 6/368 (1%) Query: 246 KGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQIL--ACGT 303 KG Y+H+MQKEI+EQP++ NT+ GRI ++ LG L + +I+ ACGT Sbjct: 2 KGPYKHFMQKEIFEQPDSAFNTMRGRIDFENCVVT-LGGLKSWLSTIRRCRRIIMIACGT 60 Query: 304 SYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 SY+S + +R FE L IP VE+AS+F R+S V R+ + +SQSGETAD++ L+ Sbjct: 61 SYHSCLATRSIFEELTEIPVSVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYC 120 Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 E G L ++ I N GSS+ R++ + NAG EIGVASTKA+T+Q L+M LS Sbjct: 121 LERGAL-TVGIVNSVGSSMSRQTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSND 179 Query: 424 KGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALA-EDFSDKHHALFLGRGDQYPIALE 482 +I+ GLQ +P +I+Q+L + +I+ L +D+ L LGRG Q+ ALE Sbjct: 180 SISRKGRHEEIIKGLQKIPEQIKQVLKLENKIKDLCNSSLNDQKSLLLLGRGYQFATALE 239 Query: 483 GALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGG 542 GALK+KEISY+H+E AGELKHG LAL+D D+P+I A + L K+ S IE+V AR G Sbjct: 240 GALKIKEISYMHSEGVLAGELKHGILALVDEDLPIIAFATRDSLFPKVMSAIEQVTARDG 299 Query: 543 QLYVFADQDAGFVSSDNMH-IIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + V ++ +S+D +H +E+P + + + +PLQL++Y +A+ +G DVD PRN Sbjct: 300 RPIVICNEGDAIISNDKVHTTLEVPETVDCLQGLLNVIPLQLISYWLAVNRGIDVDFPRN 359 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 360 LAKSVTVE 367 >4S1W-A nrPDB Length = 358 Score = 334 bits (857), Expect = 5e-92, Method: Composition-based stats. Identities = 150/368 (40%), Positives = 229/368 (62%), Gaps = 12/368 (3%) Query: 244 GDKGIYRHYMQKEIYEQPNAIKNTLTG-RISHGQVDLSELGPNADELLSKVEHIQILACG 302 +KG+Y HYM KEI+EQP ++ + + + G + + + N + + + I ++A G Sbjct: 1 AEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVK---EADRIYVIAAG 57 Query: 303 TSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 TSY++G+V + + E AG+P +V +ASEF Y + L + +SQSGETAD+ A L Sbjct: 58 TSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVE 117 Query: 363 SKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSR 422 + +LG+ SL I NV GS+L RE+D L+ +AG EI VASTKA+T Q+ VL +L +++ Sbjct: 118 TNKLGH-KSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAK 176 Query: 423 LKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDK-HHALFLGRGDQYPIAL 481 G +A I D++ L + + IE ++ +E +A DF + +A F+GR Y ++L Sbjct: 177 EHGREADI--DLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSL 234 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 EGALKLKEISYI AE +A GELKHG +ALI+ PV+ +A + ++ N++EV ARG Sbjct: 235 EGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARG 294 Query: 542 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + + + G + ++I PHV E++ P+ V LQL++Y+ AL + DVD+PRN Sbjct: 295 AHPCIISME--GLEKEGDTYVI--PHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRN 350 Query: 602 LAKSVTVE 609 LAKSVTVE Sbjct: 351 LAKSVTVE 358 >1AO0-A nrPDB Length = 459 Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats. Identities = 59/206 (28%), Positives = 99/206 (48%), Gaps = 13/206 (6%) Query: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 61 CG+ G + +I GL L++RG + AG+ D E +T + G + + Q E Sbjct: 1 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGE-KLTAHKGQGLITEVFQNGEL 59 Query: 62 HPLHGGTGIAHTRWATHGEPSEVNAHP-----HVSEHIVVVHNGIIENHEPLREELKARG 116 + G I H R+AT G N P + + + HNG + N L+++L+ +G Sbjct: 60 SKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQG 119 Query: 117 YTFVSETDTEVIAHLVNWELKQGG--TLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAAR 174 F + +DTEV+AHL+ K+ G TL++ + ++ L+GAY +IM L Sbjct: 120 SIFQTSSDTEVLAHLI----KRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPN 175 Query: 175 SGSPLVIGLGMGENFIASDQLALLPV 200 PL IG+ MG+ ++ + + V Sbjct: 176 GLRPLSIGM-MGDAYVVASETCAFDV 200 >2DF8-A nrPDB Length = 325 Score = 256 bits (653), Expect = 2e-68, Method: Composition-based stats. Identities = 98/357 (27%), Positives = 157/357 (43%), Gaps = 45/357 (12%) Query: 256 EIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNS----GMVS 311 EI + P+ I ++ + +S I L CG+S+ MV+ Sbjct: 6 EIKQTPDGIIKA------------DKVFNKVKDKISLPNRILYLGCGSSHFLSKLLAMVT 53 Query: 312 RYWFESLAGIPCDVEIASEFRYRKS--AVRRNSLMITLSQSGETADTLAGLRLSKELGYL 369 +PC SEF Y K + L + +S+SGET + L L + Sbjct: 54 NMHGGLGIALPC-----SEFLYSKETYPIGEVELAVGISRSGETTEILLALEKIN----V 104 Query: 370 GSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDAS 429 L I SSL R D +L+ A E V T +FT+ L L+ L L+A Sbjct: 105 KKLGIT-TRESSLTRMCDYSLVVPAIEE-SVVMTHSFTSFYFAYLQLLRYSYGLPPLNAG 162 Query: 430 IEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKE 489 + E+ L ++ I + E F D + +FLG G YP+ALE +LK+KE Sbjct: 163 ----------EISKATEKSLEYERYIREIVESF-DFQNIIFLGSGLLYPVALEASLKMKE 211 Query: 490 ISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFAD 549 +S +EAY E++HG A+ D V+++ E E + ++E + +G ++ V ++ Sbjct: 212 MSIFWSEAYPTFEVRHGFKAIADEKTLVVLMV--EEPFEWHEKLVKEFKNQGAKVLVISN 269 Query: 550 QDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSV 606 + IE+P + + PI Y +QLL+Y+ A+ +G + D PR L K V Sbjct: 270 SPQDL---GQDYSIELPRLSKDANPIPYLPIVQLLSYYKAVSRGLNPDNPRFLDKVV 323 >2CB0-A nrPDB Length = 333 Score = 256 bits (653), Expect = 3e-68, Method: Composition-based stats. Identities = 100/360 (27%), Positives = 160/360 (44%), Gaps = 45/360 (12%) Query: 253 MQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSG---- 308 EI + P I E + + I L CG+S+ Sbjct: 3 TLTEIKQTPKGIIKA------------DESFNQVKDKIRLPRRILYLGCGSSHFLAKLLA 50 Query: 309 MVSRYWFESLAGIPCDVEIASEFRYRKSA--VRRNSLMITLSQSGETADTLAGLRLSKEL 366 MV+ + +PC SEF Y K A + + L++ +S+SGET + L L Sbjct: 51 MVTNMHGGTGVALPC-----SEFLYSKEAYPIGKPELVVGISRSGETTEVLLALEKIN-- 103 Query: 367 GYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGL 426 L I + SSL R D +L+ E V T +FT L L+ L L Sbjct: 104 --TPKLGI-SAYESSLTRACDYSLVVPTIEE-SVVMTHSFTAFYFAYLQLLRHSYGLPLL 159 Query: 427 DASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALK 486 +A+ + E+ L + I+ + EDF D + +FLG G YP+ALE +LK Sbjct: 160 EAT----------EVAKATEKALEYENYIKEIVEDF-DFQNVIFLGSGLLYPVALEASLK 208 Query: 487 LKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYV 546 +KE++ +EAY E++HG A+ D + V+++A EL E K + E + + ++ + Sbjct: 209 MKEMAIFWSEAYPTFEVRHGFKAIADENTLVVLMA--QELFEWHKKLVNEFKGQRARVLL 266 Query: 547 FADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSV 606 ++ F + IE+P + + PI Y +QLL+Y+ A+ +G + D PR L K V Sbjct: 267 ISNSQQEF---GQDYSIEVPRLSKDATPIPYLPVVQLLSYYKAVARGLNPDNPRFLDKVV 323 >2AML-A nrPDB Length = 373 Score = 252 bits (642), Expect = 4e-67, Method: Composition-based stats. Identities = 71/329 (21%), Positives = 140/329 (42%), Gaps = 10/329 (3%) Query: 276 QVDLSELGPNADELLSKVEH----IQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEF 331 +V L++ NA++L S V++ ILA G+S N+ ++Y+ E+LA + +E Sbjct: 29 RVILADFQTNAEKLESLVKNGAKEWLILATGSSLNAAQSAKYYIENLADVRITIEEPFNH 88 Query: 332 RYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALM 391 Y + L+I +SQSG++ T++ L K+ + +A+ + S + +D+ L Sbjct: 89 LYYEKLSSHLDLVIGISQSGQSTSTISALERVKKEASVPVVALTSDVTSEIAEFADITLD 148 Query: 392 TNAGTEIGVASTKAFT-TQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQML- 449 +G E TK FT T LT++L + + +D + ++ + I + Sbjct: 149 IGSGKERVGYVTKGFTATVLTLMLTGLHFAYKTVQIDETRFNNEISAFSRAIDAIPATIA 208 Query: 450 SQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLA 509 + E E+F+ +G G E K E + ++ HGP Sbjct: 209 ETEAFYERWQEEFATAPKFTAIGYGPTVGTCKEFETKFSETVRVPSQGLDLEAFMHGPYL 268 Query: 510 LIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVE 569 ++ + + + + E+L +R + F D+ ++ ++ Sbjct: 269 EVNPQHRIFFLETASAVTERLVL----LRDYESKYTPFTYTVKFGKGEDDRTLVIPTDLD 324 Query: 570 EVIAPIFYTVPLQLLAYHVALIKGTDVDQ 598 E AP +P Q+LA+H+A +KG + + Sbjct: 325 EYQAPFLMILPFQILAHHIAELKGNKLTE 353 >3KNZ-A nrPDB Length = 366 Score = 250 bits (638), Expect = 1e-66, Method: Composition-based stats. Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 11/312 (3%) Query: 293 VEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGE 352 V I + GTSY+ + +R + + +P DV A +L++ +SQ G Sbjct: 50 VTRIILTGSGTSYHGALTARTFMQRWCALPVDVCWPFMLDDETLARSGKALVVGISQGGG 109 Query: 353 TADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAF-TTQLT 411 + TLA + ++ +G++ + ++ V +++ R +D L G E A TK + T L Sbjct: 110 SLSTLAAMERARNVGHI-TASMAGVAPATIDRAADYILTVPCGEETAGAKTKGYHCTVLN 168 Query: 412 VLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQD-KRIEALAEDFSDKHHALF 470 ++L+ +A + + LD ++ ++ + + +++ + A D Sbjct: 169 LMLLALAVAGQQQRLDGEQRRSLLLRMEKTFNHLPALVTASQAWAQTNALALRDSADIRL 228 Query: 471 LGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKL 530 G + EGALK+ E Y E HG +A +I++ P + + Sbjct: 229 TGPATLFGTVQEGALKMLETLRCPVSGYEFEEFIHGIYNAFNAQSALIMLDPQPDARQDR 288 Query: 531 KSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIF-YTVPLQLLAYHVA 589 + I + +Y Q V ++ ++ + P V + +F Y +PLQ+L + Sbjct: 289 LAQI--LGEWTPSIYRIGPQ----VENNGLN-LNFPFVNDEDFAVFEYIIPLQMLCAILP 341 Query: 590 LIKGTDVDQPRN 601 KG + P++ Sbjct: 342 PQKGINPAIPKD 353 >3G68-A nrPDB Length = 352 Score = 247 bits (631), Expect = 9e-66, Method: Composition-based stats. Identities = 84/347 (24%), Positives = 150/347 (43%), Gaps = 23/347 (6%) Query: 267 TLTGRISHGQVDLSELGPNADELLSKVEH-----IQILACGTSYNSGMVSRYWFESLAGI 321 T+ + V + E+ NAD L ++V+ I I GTSY+SG+ + + ++L I Sbjct: 3 TIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTSYHSGVQVQPYLQNLLDI 62 Query: 322 PCDVEIASEFRYRKSAV---RRNSLMITLSQSGETADTLAGLRLSKELGY-LGSLAICNV 377 DV F + N+L++ +SQ G + T ++L+++ G + S+A C Sbjct: 63 --DVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMKLAEDKGCKIASMAGCKN 120 Query: 378 PGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDAS--IEHDIV 435 + + SD L N G E A TK + L++L +++R KG+ +S +I Sbjct: 121 --ALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQIAREKGIISSEKYNEEIN 178 Query: 436 HGLQALPSRIEQMLSQDKR-IEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIH 494 L A+ +R E + K+ IE E + +G D Y LE ALKL E I Sbjct: 179 KILDAI-NRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDIYGDTLEAALKLLETMRIP 237 Query: 495 AEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGF 554 Y E HG I++D + ++ E ++ I+ + ++ Sbjct: 238 VTGYEFEEFIHGIYNAINSDSTIFILDTGKE--PRVTKMIDVLSGWTENVFAIGRDVTEN 295 Query: 555 VSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRN 601 + + I + P+ + VP+QL+ + ++G D P++ Sbjct: 296 DKNLKIDITDNPYY----QTFNFIVPIQLICGEIPTLRGVDPSVPKD 338 >1ECF-A nrPDB Length = 504 Score = 247 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 63/214 (29%), Positives = 96/214 (44%), Gaps = 19/214 (8%) Query: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRL-GKVQMLAQAAE 60 CGIVG V + + + L L++RG D+AG+ +DA + RLR+ G V + +A Sbjct: 1 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDA-NNCFRLRKANGLVSDVFEARH 59 Query: 61 EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEH---IVVVHNGIIENHEPLREELKARGY 117 L G GI H R+ T G S A P I + HNG + N LR++L Sbjct: 60 MQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKR 119 Query: 118 TFVSET-DTEVIAHLVNWELK-------QGGTLREAVLRAIPQLRGAYGTVIMDSRHPDT 169 ++ T D+E++ ++ EL + + A+ +RGAY V M H Sbjct: 120 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 179 Query: 170 LLAARSG-SPLVIGL-----GMGENFIASDQLAL 197 +G PLV+G E +AS+ +AL Sbjct: 180 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVAL 213 >1J5X-A nrPDB Length = 342 Score = 246 bits (628), Expect = 2e-65, Method: Composition-based stats. Identities = 88/362 (24%), Positives = 154/362 (42%), Gaps = 41/362 (11%) Query: 253 MQKEIYEQPNAIKNTLTGRISHGQVD--LSELGPNADELLSKVEHIQILACGTSYNSGMV 310 KEI +Q N +K + + + SE+ N + + + CG+SYN + Sbjct: 16 TLKEITDQKNELKKFFENFVLNLEKTEIFSEIQKNL------TDEVLFVGCGSSYNLALT 69 Query: 311 SRYWFESLAGIPCDVEIASEFRYRK-SAVRRNSLMITLSQSGETADTLAGLRLSKELGYL 369 Y+FE + I A E ++K + L S++G T + L + K+ + Sbjct: 70 ISYYFERVLKIRTKAIPAGEVAFQKIPDLEERGLAFLFSRTGNTTEVLLANDVLKKRNH- 128 Query: 370 GSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDAS 429 ++ I S L +ESDL L+ E + TK+F+ L L+ L K++ Sbjct: 129 RTIGITIEEESRLAKESDLPLVFPVREE-AIVMTKSFSMILLSLMFLADKIAG------- 180 Query: 430 IEHDIVHGLQALPSRIEQMLSQD-KRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLK 488 + L + K IE + D + H +FLG + + ++LE ALK Sbjct: 181 ---NSTERFSELVGYSPEFFDISWKVIEKI--DLKEHDHFVFLGMSEFFGVSLESALKCI 235 Query: 489 EISYIHAEAYAAGELKHGPLALIDADMPVIV--VAPNNELLEKLKSNIEEVRARGGQLYV 546 E+S +EAY+ E +HGP AL+ V + V+ +E ++L+ +E + G + Sbjct: 236 EMSLTFSEAYSTLEYRHGPKALVKKGTLVFMQKVSGMDEQEKRLRKELESL---GATVLE 292 Query: 547 FADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSV 606 + +P + + TVP Q+L Y A+ +G D+P +L K+V Sbjct: 293 VGEGGD------------IPVSNDWKSAFLRTVPAQILGYQKAISRGISPDKPPHLEKTV 340 Query: 607 TV 608 + Sbjct: 341 VL 342 >3FJ1-A nrPDB Length = 344 Score = 244 bits (623), Expect = 7e-65, Method: Composition-based stats. Identities = 97/370 (26%), Positives = 164/370 (44%), Gaps = 41/370 (11%) Query: 247 GIYRHY--MQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTS 304 G+ +H M++EI E P A++ L HG D++ + A L + +A G+S Sbjct: 1 GMTQHITRMRREIDEIPEAVQRLL----DHGAQDVARVA--AVLRLRDPSFVATVARGSS 54 Query: 305 YNSGMVSRYWFESLAGIPCDVEIASEF-RYRKSAVRRNSLMITLSQSGETADTLAGLRLS 363 + Y E L G+P S Y +L + +SQSG++ D +A R + Sbjct: 55 DHVCTYLSYAAELLLGLPVASLGPSVASVYDARLRLDRALCLAVSQSGKSPDIVAMTRNA 114 Query: 364 KELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRL 423 G L +A+ N S L S + +AG E+ VA+TK F T LML+A + Sbjct: 115 GRDGAL-CVALTNDAASPLAGVSAHTIDIHAGPELSVAATKTFVTSAVAGLMLLADWAED 173 Query: 424 KGLDASIEHDIVHGLQALPSRIEQMLSQDKRIE--ALAEDFSDKHHALFLGRGDQYPIAL 481 GL A++ + + L+ RI+ + + LGRG ++ Sbjct: 174 DGLRAALG------------NLPETLAAASRIDWPEMRVAIGARPSLFTLGRGTSLAVSN 221 Query: 482 EGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARG 541 E ALK KE +HAE+Y++ E+ HGP+++++ PV+ A + L +++ A+G Sbjct: 222 EAALKFKETCQLHAESYSSAEVLHGPVSIVEEGFPVLGFAAGDAAEAPLAEIADQIAAKG 281 Query: 542 GQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALI------KGTD 595 ++ G V+ + +E V + T PL L+ +++ +G D Sbjct: 282 ATVFA----TTGRVTRARV-------LEHVRSGHALTDPLSLIVSFYSMVEAFASERGID 330 Query: 596 VDQPRNLAKS 605 D PR+L K Sbjct: 331 PDAPRHLNKV 340 >3C3J-A nrPDB Length = 384 Score = 240 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 79/369 (21%), Positives = 151/369 (40%), Gaps = 40/369 (10%) Query: 252 YMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVE--HIQILACGTSYNSGM 309 + ++EI QP A +LT + L N E L + E I + GTS G Sbjct: 15 WTEEEIRHQPRAWIRSLTNIDA-----LRSALNNFLEPLLRKENLRIILTGAGTSAFIGD 69 Query: 310 VSRYWF-----ESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSK 364 + W ++ + +P + + Y A L+I+ +SG + +++A + L+ Sbjct: 70 IIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA--HPLLLISFGRSGNSPESVAAVELAN 127 Query: 365 EL-GYLGSLAI-CNVPGS----SLVRESDLALMTNAGT-EIGVASTKAFTTQLTVLLMLV 417 + L I CN G+ ++ ++ AL+ A T + G A T + TT + L + Sbjct: 128 QFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMMASCLAVF 187 Query: 418 AKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQY 477 A + +++ D+ R + +L+ ++ ++LG G Sbjct: 188 AP----ETINSQTFRDVA-------DRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQ 236 Query: 478 PIALEGALKLKEISYIHAEAY--AAGELKHGPLALIDADMPVIVVAPNNELLEKLKSN-I 534 A E ALK+ E++ A+ + +HGP +L+D + V+V ++ + + + Sbjct: 237 GAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDLL 296 Query: 535 EEVR--ARGGQLYVFADQDAGFVSSDNMHIIEMP--HVEEVIAPIFYTVPLQLLAYHVAL 590 E+R + ++ A + + V+ HII P H +V + + Q A +L Sbjct: 297 AELRRDNQAMRVIAIAAESSDIVA-AGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSL 355 Query: 591 IKGTDVDQP 599 G D P Sbjct: 356 HMGNTPDTP 364 >3HBA-A nrPDB Length = 334 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 93/355 (26%), Positives = 155/355 (43%), Gaps = 32/355 (9%) Query: 252 YMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVS 311 M++E P I L + LG E K + + I+ G+S ++G+ + Sbjct: 7 IMEQEARTAPQKIAEQLLANDA----ITESLGSVLREF--KPKFVMIVGRGSSDHAGVFA 60 Query: 312 RYWFESLAGIPCDVEIASEF-RYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLG 370 +Y FE A IP S Y K+ L+I +SQSG + D LA R++K G Sbjct: 61 KYLFEIEASIPTFAAAPSVASVYGKTLKLAGGLVIVISQSGRSPDILAQARMAKNAGAF- 119 Query: 371 SLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASI 430 +A+ N + + D+ + AG E VA+TK++ L+ LL + AK ++ Sbjct: 120 CVALVNDETAPIKDIVDVVIPLRAGEEKAVAATKSYLATLSALLQVAAKWTQ-------- 171 Query: 431 EHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEI 490 +V + +LP ++ + + ++ A +D + + LGRG Y ++ E ALKLKE+ Sbjct: 172 NESLVEAVNSLPQALQAAVDAEPQLR--AGSLTDVKNLVVLGRGFGYAVSKEIALKLKEV 229 Query: 491 SYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQ 550 IHAEA+++ E HGP+ L++ + ++ V +E I V+ RG L Sbjct: 230 CAIHAEAFSSAEFLHGPVTLVEKKLSILDVCIRDESYGSHVEQIANVKQRGANLIHLHQT 289 Query: 551 DAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKS 605 A + +V A VA+ G + D+P L K Sbjct: 290 SADIHPRIAPLALLQRFYIDVAA--------------VAIALGINPDKPAGLKKV 330 >3ODP-A nrPDB Length = 393 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 79/371 (21%), Positives = 155/371 (41%), Gaps = 37/371 (9%) Query: 251 HYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMV 310 + KEI QP + T +S + S L A + +K I I G+S G Sbjct: 19 YITAKEICNQPKLWRETYEIILSQREKLKSFLDNFAKKPNAK---IVITGAGSSAFVGNS 75 Query: 311 SRYWFE-----SLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKE 365 + + I ++ F Y K +L+I+ ++SG + ++ A + L+++ Sbjct: 76 VVSYLNAKENIKIEAIATTDIVSHPFYYLKKD--EPTLLISCARSGNSPESTAAVTLAEK 133 Query: 366 L-GYLGSLAI-CNVPGSSLVR-----ESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVA 418 + + L I CN G + S L LM + G A T +F+T L L L+ Sbjct: 134 IVDDISHLIITCNSEGKLALHAKRNYNSFLLLMPEESNDKGFAMTGSFSTMLLSCL-LIF 192 Query: 419 KLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYP 478 L +L+ + IE + G + L + +E M ++LG + + Sbjct: 193 NLDKLESIGKQIESISMQGEKVLVNNVELMKKIVGE---------KFKRTVYLGAANAFG 243 Query: 479 IALEGALKLKEISYIH-AEAYAAG-ELKHGPLALIDADMPVIVVAPNNELLEKLKSN-IE 535 +A E ALK+ E++ A Y +HGP ++ID + +++ N+ + + + ++ Sbjct: 244 LAKESALKVLELTAGKIATLYDTPLGFRHGPKSIIDDETLIVIFFSNDTYAREYEYDLLK 303 Query: 536 EVRARGGQLYV--FADQDAGFVSSDNMHII-----EMPHVEEVIAPIFYTVPLQLLAYHV 588 EV ++ G V ++ + + ++ + I E + ++ + Y + Q+ A+ Sbjct: 304 EVYSQNGNHKVLAISEYEDKLIEDNSDYFIAINKEEQEYEDDSFLSLDYLLNAQMYAFIN 363 Query: 589 ALIKGTDVDQP 599 ++ G D P Sbjct: 364 SMELGIGPDNP 374 >3I0Z-A nrPDB Length = 389 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 75/374 (20%), Positives = 154/374 (41%), Gaps = 43/374 (11%) Query: 250 RHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACG---TSYN 306 +EIY+QP+ + Q E+ E+ K ++I+++ G ++Y Sbjct: 15 AEITTREIYQQPDVWREAFE----FYQAKREEIAAFLQEIADKHDYIKVILTGAGTSAYV 70 Query: 307 SGMVSRYWFE-------SLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAG 359 + Y+ E + I +A+ Y K V +++++ ++SG + ++LA Sbjct: 71 GDTLLPYFKEVYDERKWNFNAIATTDIVANPATYLKKDVA--TVLVSFARSGNSPESLAT 128 Query: 360 LRLSKEL-GYLGSLAICNVPGSSLV-----RESDLALMTNA-GTEIGVASTKAFTTQLTV 412 + L+K L L + I L + +L L+ A + G A T +FT+ + Sbjct: 129 VDLAKSLVDELYQVTITCAADGKLALQAHGDDRNLLLLQPAVSNDAGFAMTSSFTSMMLT 188 Query: 413 LLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLG 472 L++ D + + + S ++L + + ++ L + D + ++LG Sbjct: 189 TLLVF---------DPTEFAVKSERFEVVSSLARKVLDKAEDVKELVD--LDFNRVIYLG 237 Query: 473 RGDQYPIALEGALKLKEISYIH-AEAYAAG-ELKHGPLALIDADMPVIVVAPNNELLEKL 530 G + +A E LK+ E++ A Y + +HGP +LI+ + V+V + K Sbjct: 238 AGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSLINDNTVVLVFGTTTDYTRKY 297 Query: 531 KSNIEEVRARGG-----QLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLA 585 +++ VR G ++ + +DQ G + + + + ++ Y V QL A Sbjct: 298 --DLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCGGVLNDIYRVFPYIVYAQLFA 355 Query: 586 YHVALIKGTDVDQP 599 +L D P Sbjct: 356 LLTSLKVENKPDTP 369 >3FKJ-A nrPDB Length = 347 Score = 193 bits (490), Expect = 2e-49, Method: Composition-based stats. Identities = 64/326 (19%), Positives = 122/326 (37%), Gaps = 29/326 (8%) Query: 291 SKVEHIQILACGTSYNSGMVSRYWFESLAG-IPCDVEIASEFRY-RKSAVRRNSLMITLS 348 +E + + CG S +Y+ + A + ++EF + A+ +NS++I S Sbjct: 38 QNIERVWFVGCGGSLTGFWPGKYFLDCEASKLAVGYITSNEFVHATPKALGKNSVVILAS 97 Query: 349 QSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLAL---MTNAGTEIGVASTKA 405 Q G TA+T+A R+++E G ++ + P + L SD + + A KA Sbjct: 98 QQGNTAETVAAARVAREKGA-ATIGLVYQPDTPLCEYSDYIIEYQWARYPETVDPAQQKA 156 Query: 406 FTTQLTVLLMLVAKLSRLKGLDA-----SIEHDIVHGLQALPSRIEQMLSQDKRIEALAE 460 L + L ++A+ D D+VHG Q + + A Sbjct: 157 -AYSLWLALEILAQTEGYAQYDELVSAFGRFSDVVHGAQR---------QVQEDAQRFAA 206 Query: 461 DFSDKHHALFLGRGDQYPIA-LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIV 519 ++ D+ +G G + A E L E+ +I++ + +GE HGP + + P I+ Sbjct: 207 EWKDEKVVYMMGSGPSFGAAHQESICILLEMQWINSASIHSGEYFHGPFEITEPGTPFIL 266 Query: 520 VAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTV 579 + + I + G+L + G V E + + Sbjct: 267 LQSSGRTRPLDDRAIRFIERYQGKLQLIDADKLGIQD-------LSTDVGEYFCGLLHNC 319 Query: 580 PLQLLAYHVALIKGTDVDQPRNLAKS 605 L + +A + + R + K Sbjct: 320 VLDVYNLALATARNHPLTTRRYMWKV 345 >3EUA-A nrPDB Length = 329 Score = 193 bits (490), Expect = 2e-49, Method: Composition-based stats. Identities = 80/332 (24%), Positives = 141/332 (42%), Gaps = 21/332 (6%) Query: 280 SELGPNADELLSK-VEHIQILACGTSYNSGMVSRYWFESLA-GIPCDVEIASEFRYRKSA 337 E+ +L K ++H+ +ACG S S+Y F+ + I D+ A+EF R Sbjct: 11 REVQAFLQDLKGKTIDHVFFVACGGSSAIMYPSKYVFDRESKSINSDLYSANEFIQRNPV 70 Query: 338 -VRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGT 396 + SL+I S SG T +T+ ++ G L ++A+ P S L +E+ + G Sbjct: 71 QLGEKSLVILCSHSGNTPETVKAAAFARGKGAL-TIAMTFKPESPLAQEAQYVAQYDWGD 129 Query: 397 EIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHD-IVHGLQALPSRIEQMLSQDKRI 455 E A T VL +V L+ L+ + + + + GL L + E+ L Q+ Sbjct: 130 E-----ALAINTNYGVLYQIVF--GTLQVLENNTKFEQAIEGLDQLQAVYEKALKQEADN 182 Query: 456 -EALAEDFSDKHHALFLGRGDQYPIALEGA-LKLKEISYIHAEAYAAGELKHGPLALIDA 513 + A+ + + G Y +A + L E+ +IH+ A AGE HGP +ID Sbjct: 183 AKQFAKAHEKESIIYTMASGANYGVAYSYSICILMEMQWIHSHAIHAGEYFHGPFEIIDE 242 Query: 514 DMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIA 573 +P I++ +E + + + G +L V F + D+ V+ +A Sbjct: 243 SVPFIILLGLDETRPLEERALTFSKKYGKKLTVLDAASYDFTAIDDS-------VKGYLA 295 Query: 574 PIFYTVPLQLLAYHVALIKGTDVDQPRNLAKS 605 P+ L+ A +A + + R + K Sbjct: 296 PLVLNRVLRSYADELAEERNHPLSHRRYMWKV 327 >2A3N-A nrPDB Length = 355 Score = 171 bits (433), Expect = 9e-43, Method: Composition-based stats. Identities = 47/228 (20%), Positives = 103/228 (45%), Gaps = 13/228 (5%) Query: 296 IQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR-KSAVRRNSLMITLSQSGETA 354 + + G S M + + L +P VE A+E ++ + ++S++ITLS+SG+T Sbjct: 57 LFFASVGGSLAPMMAINEFAKELTTLPVYVEQAAELIHKGNKRLNKDSVVITLSKSGDTK 116 Query: 355 DTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLL 414 +++A K G + ++ + +D L A I + + +L Sbjct: 117 ESVAIAEWCKAQG---------IRVVAITKNADSPLAQAATWHIPMRHKNGVEYEYMLLY 167 Query: 415 MLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQ-DKRIEALAEDFSDKHHALFLGR 473 L ++ AS + L+ LP+ + + + D + +A+A + + + +++G Sbjct: 168 WLFFRVLSRNNEFASYDR-FASQLEILPANLLKAKQKFDPQADAIASRYHNSDYMMWVGG 226 Query: 474 GDQYP-IALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVV 520 + + + L L+E+ + ++ E HG L L++ D+P+I+V Sbjct: 227 AEMWGEVYLFSMCILEEMQWKRTRPVSSAEFFHGALELLEKDVPLILV 274 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 25/167 (14%), Positives = 61/167 (36%), Gaps = 11/167 (6%) Query: 426 LDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSD--KHHALFLGRGDQYP---IA 480 ++ ++ + + ++++ ++ E +A++ F G Sbjct: 13 MNNQEKNMLGFNQDEYLTSAREIIAARQKAEQVADEIYQAGFSSLFFASVGGSLAPMMAI 72 Query: 481 LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR 540 E A KE++ + A EL H ++ D VI ++ + + E + E +A+ Sbjct: 73 NEFA---KELTTLPVYVEQAAELIHKGNKRLNKDSVVITLSKSGDTKES-VAIAEWCKAQ 128 Query: 541 GGQLYVFADQDAGFVSSDNMHIIEMPHVE--EVIAPIFYTVPLQLLA 585 G ++ ++ I M H E + Y + ++L+ Sbjct: 129 GIRVVAITKNADSPLAQAATWHIPMRHKNGVEYEYMLLYWLFFRVLS 175 >1CT9-A nrPDB Length = 553 Score = 170 bits (431), Expect = 1e-42, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 88/238 (36%), Gaps = 61/238 (25%) Query: 22 RRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEP 81 R + +RG D +G+ D + RL V G Sbjct: 25 RLMRHRGPDWSGIYASD--NAILAHERLSIVD----------------------VNAG-- 58 Query: 82 SEVNAHPHVSEHIV--VVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQG 139 A P ++ + NG I NH+ LR E R Y F + +D EVI L Sbjct: 59 ----AQPLYNQQKTHVLAVNGEIYNHQALRAEYGDR-YQFQTGSDCEVILAL-------- 105 Query: 140 GTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSG---SPLVIGLG-MGENFIASDQL 195 +E + L+G + + DS D L R PL +G G+ ++AS+ Sbjct: 106 --YQEKGPEFLDDLQGMFAFALYDSEK-DAYLIGRDHLGIIPLYMGYDEHGQLYVASEMK 162 Query: 196 ALLPVTR--------RFIFLEEGDIAEITRRSVNIFDKTGAEVK-----RQDIESNLQ 240 AL+PV R +++ ++G+I R +D V RQ +E +++ Sbjct: 163 ALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVK 220 >4LZJ-A nrPDB Length = 303 Score = 70.2 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 25/151 (16%) Query: 290 LSKVEHIQILACGTSYNSGMV----SRYWFESLAGIPCDVEIASEFRYRKSA-------- 337 + + + GTS G++ F + + E R Sbjct: 65 FQQGGRLIYIGAGTSGRLGVLDASECPPTFGVSTEMVKGIIAGGECAIRHPVEGAEDNTK 124 Query: 338 ----------VRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESD 387 +N +++ ++ SG T +AGL+ +K LG L +++I + P S + +D Sbjct: 125 AVLNDLQSIHFSKNDVLVGIAASGRTPYVIAGLQYAKSLGAL-TISIASNPKSEMAEIAD 183 Query: 388 LALMTNAGTEI--GVASTKAFTTQLTVLLML 416 +A+ T G EI G + K+ T Q VL ML Sbjct: 184 IAIETIVGPEILTGSSRLKSGTAQKMVLNML 214 >4S12-A nrPDB Length = 298 Score = 62.1 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 71/188 (37%), Gaps = 29/188 (15%) Query: 253 MQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSR 312 M I ++ + + I + +++ A + L + L GTS G++ Sbjct: 29 MLTRINDEDRKVPEAIRLVIPN----IAQAVDLAAKALRDGGRLIYLGAGTSGRLGVLDA 84 Query: 313 Y------------WFESLAGIPCDVEIASEFRYRKSAVRRNSL----------MITLSQS 350 +AG P + A E ++ L ++ L+ S Sbjct: 85 SECPPTFGVPHGRVIGLIAGGPGALLKAVEGAEDDVSLGERDLRDLQLTATDMVVGLAAS 144 Query: 351 GETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVAST--KAFTT 408 G T + LR +++LG + AI P S + +E+ +A+ G E ST K+ T Sbjct: 145 GRTPYVIGALRFARQLG-CPTAAISCNPDSPIAQEALVAISPVVGPEALTGSTRMKSGTA 203 Query: 409 QLTVLLML 416 Q VL ML Sbjct: 204 QKLVLNML 211 >3FXA-A nrPDB Length = 201 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 31/192 (16%), Positives = 69/192 (35%), Gaps = 11/192 (5%) Query: 247 GIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVE-HIQILACGTSY 305 G+ + + I++ + +V E E +++ I + CGTS Sbjct: 1 GMDKQAILDNIHQ---TWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTS- 56 Query: 306 NSGMVSRYWFESLAGI--PCDVEIASEFRYRKS-AVRRNSLMITLSQSGETADTLAGLRL 362 G+ ++ S I P S+ + +++ ++I +S+ G T + L + Sbjct: 57 --GVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPA 114 Query: 363 SKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSR 422 K G + + P S + +E+D+ + E + A + + V+ A + Sbjct: 115 CKTKGSTL-IGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVC 173 Query: 423 LKGLDASIEHDI 434 L + Sbjct: 174 LMTYMNYTKEQF 185 >5UQI-A nrPDB Length = 198 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 68/188 (36%), Gaps = 18/188 (9%) Query: 250 RHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGM 309 +H+M E+ I LSE L S + + G S G+ Sbjct: 11 KHFMHNELKAVEEVI-----------DSPLSEFANLIKVLQSCQGKVVFIGVGKS---GI 56 Query: 310 VSRYWFESLAGI--PCDVEIASEFRYRKS-AVRRNSLMITLSQSGETADTLAGLRLSKEL 366 ++R + A P +E + V ++ ++I +S SGETA+ LA L K++ Sbjct: 57 IARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGETAEILATLPSLKKM 116 Query: 367 GYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGL 426 G ++ SSL DL++ +E + VL++ A L L Sbjct: 117 GN-YLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTVVLVVGDAVALALSEL 175 Query: 427 DASIEHDI 434 D Sbjct: 176 KKFTRADF 183 >1VIM-A nrPDB Length = 200 Score = 52.9 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 53/132 (40%), Gaps = 9/132 (6%) Query: 262 NAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGI 321 + + +H + E +L+ I ++ G S G +++ + L + Sbjct: 19 EVVSEHIKNLRNHIDL---ETVGEMIKLIDSARSIFVIGAGRS---GYIAKAFAMRLMHL 72 Query: 322 PCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSS 381 V + E + +++ +S SGET + + +K++G +A+ SS Sbjct: 73 GYTVYVVGETV--TPRITDQDVLVGISGSGETTSVVNISKKAKDIGS-KLVAVTGKRDSS 129 Query: 382 LVRESDLALMTN 393 L + +D+ ++ Sbjct: 130 LAKMADVVMVVK 141 >1TK9-A nrPDB Length = 188 Score = 49.0 bits (115), Expect = 6e-06, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 22/137 (16%) Query: 279 LSELGPNADELLSKVEHIQILACGTS------YNSGMVSRYWFES--LAGIPCDVEIA-- 328 ++++G E L K I I G S + + + RY E LAGI + + Sbjct: 28 IAKVGELLCECLKKGGKILICGNGGSAADAQHFAAELSGRYKKERKALAGIALTTDTSAL 87 Query: 329 --------SEFRYRKSAV---RRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNV 377 EF + + ++I +S SG++ + L L+ +KEL L L + Sbjct: 88 SAIGNDYGFEFVFSRQVEALGNEKDVLIGISTSGKSPNVLEALKKAKELNML-CLGLSGK 146 Query: 378 PGSSLVRESDLALMTNA 394 G + + D L+ + Sbjct: 147 GGGMMNKLCDHNLVVPS 163 >3ETN-A nrPDB Length = 220 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 9/145 (6%) Query: 262 NAIKNTLT-GRISHGQVDLSELGPNADELL-----SKVEHIQILACGTSYNSGMVSRYWF 315 +I+ L + + +++ A EL+ K + G + M F Sbjct: 22 ESIQELLQKEAQAVLNIPVTDAYEKAVELIVEQIHRKKGKLVTSGMGKAGQIAMNIATTF 81 Query: 316 ESLAGIPCDVEIASEFRYRKS-AVRRNSLMITLSQSGETADTLAGLRLSKELG-YLGSLA 373 GIP SE ++ ++ N L++ +S SG+T + + +L+ L L + Sbjct: 82 -CSTGIPSVFLHPSEAQHGDLGILQENDLLLLISNSGKTREIVELTQLAHNLNPGLKFIV 140 Query: 374 ICNVPGSSLVRESDLALMTNAGTEI 398 I P S L ESD+ L T E+ Sbjct: 141 ITGNPDSPLASESDVCLSTGHPAEV 165 >1M3S-A nrPDB Length = 186 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%) Query: 280 SELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVR 339 E AD +LS + I G S G++++ + L + + I E + Sbjct: 25 EEADQLADHILSSHQ-IFTAGAGRS---GLMAKSFAMRLMHMGFNAHIVGEIL--TPPLA 78 Query: 340 RNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGT 396 L+I S SGET + +K L + A+ P SS+ +++DL + Sbjct: 79 EGDLVIIGSGSGETKSLIHTAAKAKSL-HGIVAALTINPESSIGKQADLIIRMPGSP 134 >5LU5-A nrPDB Length = 197 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 339 RRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTE 397 ++I S SG++ + LA R +K G + + G + DL L + Sbjct: 114 NEGDVLIGYSTSGKSPNILAAFREAKAKG-MTCVGFTGNRGGEMRELCDLLLEVPSADT 171 >3MDN-A nrPDB Length = 274 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 19/138 (13%) Query: 30 DSAGLAVVDAEGHMTRLRRLGKVQMLAQA-------AEEHPLHGGTGIAHTRWATHGEPS 82 D G+A DA G + + A A H + G ++H R +T S Sbjct: 44 DGFGVAWYDARPE------PGLYRDVYPAWSDPNLRAVAHHVRSGLFLSHVRASTGSCIS 97 Query: 83 EVNAHPHVSEHIVVVHNGIIENHEPLREE----LKARGYTFVSE-TDTEVIAHLVNWELK 137 N HP + +HNG + E R++ + YT+ TD+EV+ L E Sbjct: 98 RNNCHPFAARRWCFMHNGQVGGFEAFRKQADMAIADEFYTYRKGSTDSEVLFLLALSEGL 157 Query: 138 QGGTLREAVLRAIPQLRG 155 + A+ RAI +L G Sbjct: 158 EHDP-HGALARAIARLEG 174 >1X9I-A nrPDB Length = 302 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 51/287 (17%), Positives = 95/287 (33%), Gaps = 34/287 (11%) Query: 295 HIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETA 354 + I G S + R + + +VE+ + Y A R+ L+I +S SG T Sbjct: 39 RLYISGMGGSGVVADLIRDFSLTW---NWEVEVIAVKDYFLKA--RDGLLIAVSYSGNTI 93 Query: 355 DTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLL 414 +TL + +K + ++AI G L + ++ A A LT L Sbjct: 94 ETLYTVEYAKRR-RIPAVAITT--GGRLAQMGVPTVIVP----KASAPRAALPQLLTAAL 146 Query: 415 MLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRG 474 +VAK+ + +P +E + I L E+F + + Sbjct: 147 HVVAKVYGIDV--------------KIPEGLEP--PNEALIHKLVEEF--QKRPTIIAAE 188 Query: 475 DQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNI 534 +A + E + I E H I+ +V + + ++ + + Sbjct: 189 SMRGVAYRVKNEFNENAKIEPSVEILPEAHH---NWIEGSERAVVALTSPHIPKEHQERV 245 Query: 535 EEVRAR-GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVP 580 + GG +Y G +S I + E+ P Sbjct: 246 KATVEIVGGSIYAVEMHPKGVLSFLRDVGIASVKLAEIRGVNPLATP 292 >2I2W-A nrPDB Length = 212 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 23/169 (13%), Positives = 60/169 (35%), Gaps = 29/169 (17%) Query: 248 IYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNS 307 +Y+ ++ E+ E + N L + + + + + + G S+ Sbjct: 21 MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVL--LADSFKAGGKVLSCGNGGSHCD 78 Query: 308 GMVSRYWFESLA-----------GIPCDV-----EIASEF-------RYRKSAVRRNSLM 344 M ++ E L I + ++F RY ++ R ++ Sbjct: 79 AM---HFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVL 135 Query: 345 ITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTN 393 + +S SG +A+ + + ++E G + + + G + +D+ + Sbjct: 136 LGISTSGNSANVIKAIAAAREKG-MKVITLTGKDGGKMAGTADIEIRVP 183 >5I01-A nrPDB Length = 204 Score = 34.4 bits (77), Expect = 0.17, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 318 LAGIPCDVEIASEFRYRKSAVRR-NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICN 376 L I D F + A+ R +++ +S SG +A+ + ++ + E + +A+ Sbjct: 91 LTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERD-MHVIALTG 149 Query: 377 VPG---SSLVRESDLALMTN 393 G +++++++D+ L Sbjct: 150 RDGGKIAAMLKDTDVLLNVP 169 >2Q8N-A nrPDB Length = 460 Score = 33.6 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 22/148 (14%), Positives = 51/148 (34%), Gaps = 29/148 (19%) Query: 263 AIKNTLTGRISHGQVD---LSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFE--S 317 A++N + ++D + + D +++ + + +L G S + Y + Sbjct: 46 AVRNFVENTPDFAKLDRSWIDSVKSLEDWIIN-FDTVVVLGIGGSGLGNLALHYSLRPLN 104 Query: 318 LAGI---------------PCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 + D ++ S R + +L +S+SG TA+ +A + Sbjct: 105 WNEMTREERNGYARVFVVDNVDPDLMSSVLDRIDP--KTTLFNVISKSGSTAEVMATYSI 162 Query: 363 SK------ELGYLGSLAICNVPGSSLVR 384 ++ L + I P +R Sbjct: 163 ARGILEAYGLDPREHMLITTDPEKGFLR 190 >6BFZ-A nrPDB Length = 449 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Query: 341 NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGV 400 NS++I +Q G +TLA ++++K+ GY ++ + +DLA+ T AG Sbjct: 354 NSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDAT-IADLAVGTAAGQIKTG 412 Query: 401 ASTKA 405 + +++ Sbjct: 413 SMSRS 417 >3TQI-A nrPDB Length = 527 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%) Query: 414 LMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGR 473 L + K K + + + L+ + E+ ++ + E+ + K + +LG+ Sbjct: 277 LNVFQKHLGAKVICVDAKDRFMKALKGISDPEEKRKIAGEQFIRVFEEQAKKLNVKWLGQ 336 Query: 474 GDQYPIALEGA 484 G YP +E A Sbjct: 337 GTIYPDVIESA 347 >3O85-A nrPDB Length = 122 Score = 29.8 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 27/69 (39%) Query: 489 EISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFA 548 E+ I A+A + H PLA D +P + + N L ++ + A G+ Sbjct: 49 ELVIIAADADPIEIVLHLPLACEDKGVPYVFIGSKNALGRACNVSVPTIVASIGKHDALG 108 Query: 549 DQDAGFVSS 557 + A V Sbjct: 109 NVVAEIVGK 117 >1ZZG-A nrPDB Length = 415 Score = 29.8 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 15/115 (13%) Query: 262 NAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQ----------ILACGTSYNSGMVS 311 A + L R G + P E L +V + ++ G S Sbjct: 25 EARRRLLAKRGEPGSMLGWMDLPEDTETLREVRRYREANPWVEDFVLIGIGGSALGPKAL 84 Query: 312 RYWFESLAGIPCD----VEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRL 362 F + +G+ VE R ++ R +L+ +S+SG TA+TLAGL + Sbjct: 85 EAAF-NESGVRFHYLDHVEPEPILRLLRTLDPRKTLVNAVSKSGSTAETLAGLAV 138 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.123 0.289 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,607,863 Number of Sequences: 36641 Number of extensions: 680001 Number of successful extensions: 2332 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 2156 Number of HSP's gapped (non-prelim): 97 length of query: 609 length of database: 10,336,785 effective HSP length: 103 effective length of query: 506 effective length of database: 6,562,762 effective search space: 3320757572 effective search space used: 3320757572 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)