BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P16370 (318 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3HOY-C nrPDB 662 0.0 3J0K-C nrPDB 561 e-160 5X4Z-C nrPDB 327 6e-90 3H0G-C nrPDB 320 6e-88 5IYA-C nrPDB 228 3e-60 4QIW-D nrPDB 98 6e-21 6F44-C nrPDB 86 2e-17 5LMX-C nrPDB 86 2e-17 2PMZ-D nrPDB 70 1e-12 2WB1-D nrPDB 69 3e-12 1IW7-A nrPDB 32 0.51 4YUU-B1 nrPDB 30 1.6 1PXZ-A nrPDB 29 2.4 5XXU-P nrPDB 28 3.6 1HQM-A nrPDB 28 4.9 6B44-C nrPDB 28 5.1 5IG1-A nrPDB 28 7.0 >3HOY-C nrPDB Length = 347 Score = 662 bits (1709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/317 (100%), Positives = 317/317 (100%) Query: 2 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE 61 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE Sbjct: 31 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE 90 Query: 62 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 121 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV Sbjct: 91 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 150 Query: 122 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 181 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD Sbjct: 151 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 210 Query: 182 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD Sbjct: 211 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 270 Query: 242 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS 301 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS Sbjct: 271 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS 330 Query: 302 NASQMGNTGSGGYDNAW 318 NASQMGNTGSGGYDNAW Sbjct: 331 NASQMGNTGSGGYDNAW 347 >3J0K-C nrPDB Length = 268 Score = 561 bits (1445), Expect = e-160, Method: Compositional matrix adjust. Identities = 268/268 (100%), Positives = 268/268 (100%) Query: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD Sbjct: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 Query: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI 120 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI Sbjct: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI 120 Query: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY Sbjct: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 Query: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV Sbjct: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 Query: 241 DQVVVRGIDTLQKKVASILLALTQMDQD 268 DQVVVRGIDTLQKKVASILLALTQMDQD Sbjct: 241 DQVVVRGIDTLQKKVASILLALTQMDQD 268 >5X4Z-C nrPDB Length = 304 Score = 327 bits (837), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 155/263 (58%), Positives = 200/263 (76%), Gaps = 2/263 (0%) Query: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 MS+E P+V I A D V+ +LS+V+L++ANSLRR M+AE+PTLAID VE++ NT+VLAD Sbjct: 1 MSKE-PKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLAD 59 Query: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESE-STTNVYSKDLV 119 EFI+HRLGLIPL S D+E+++YSRDC CED+CD+CSVVL L A E E TT+VYS L+ Sbjct: 60 EFISHRLGLIPLVSEDVEEMKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYSSSLI 119 Query: 120 IVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFE 179 VS N+G P+ +D G+L+CKLR QEL + C+AKKGIAKEHAKW P +AI FE Sbjct: 120 KVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSAIAFE 179 Query: 180 YDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIP 239 YDP NKLKHTD+W+E D+ KEWP SK +E+PP G+ FDYKA+ + FYM VE+ GS+ Sbjct: 180 YDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETTGSLK 239 Query: 240 VDQVVVRGIDTLQKKVASILLAL 262 +QV RGI TLQ+K+A++L L Sbjct: 240 ANQVFSRGIKTLQEKLANVLFEL 262 >3H0G-C nrPDB Length = 297 Score = 320 bits (820), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 147/276 (53%), Positives = 207/276 (75%), Gaps = 13/276 (4%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ DEF+AHR Sbjct: 6 HITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHR 65 Query: 67 LGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 121 LG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y++DLV+ Sbjct: 66 LGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVS 125 Query: 122 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 181 SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A+ FEYD Sbjct: 126 SN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 Query: 182 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 PWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESVGSIP + Sbjct: 183 PWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPN 242 Query: 242 QVVVRGIDTLQKKVASILLAL-----TQMDQDKVNF 272 +++V+G+ LQ+K+A ++ L TQ+ +++N Sbjct: 243 EIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNM 278 >5IYA-C nrPDB Length = 275 Score = 228 bits (581), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 123/270 (45%), Positives = 172/270 (63%), Gaps = 10/270 (3%) Query: 6 PQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAH 65 P V+I E + +NV FI+ N DLA+ANS+RRV IAE+P +AID V+++ N++VL DEFIAH Sbjct: 7 PTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAH 66 Query: 66 RLGLIPLQSMDI-EQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLV----I 120 RLGLIPL S DI ++L+YSRDC CE+ C +CSV TL + T +V S+DL+ Sbjct: 67 RLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPR 126 Query: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 V + RN + E + +LI KLRKGQEL+L AKKG KEHAKW P A + FEY Sbjct: 127 VIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEY 186 Query: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 DP N L+HT Y +EWP+S+ E ++ ++ P+D + + FY NVES GS+ Sbjct: 187 DPDNALRHTVY----PKPEEWPKSEYSELDEDESQA-PYDPNGKPERFYYNVESCGSLRP 241 Query: 241 DQVVVRGIDTLQKKVASILLALTQMDQDKV 270 + +V+ + L+KK++ + L+ Q V Sbjct: 242 ETIVLSALSGLKKKLSDLQTQLSHEIQSDV 271 >4QIW-D nrPDB Length = 259 Score = 97.8 bits (242), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 54/273 (19%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 + KI E D++ FI+S VD+ AN+LRR +++E+PT A+D VE N + L DE IAHR Sbjct: 3 EFKILEKRPDSIKFIVSGVDVPFANALRRTILSEVPTFAVDEVEFLENDSALFDEIIAHR 62 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMG 126 L +IPL + +S D D +V L+L+A E VYS DL Sbjct: 63 LAMIPLTT---PHERFSLDAL---ELDDYTVTLSLEA----EGPGMVYSGDL-------- 104 Query: 127 RNIGHPIIQDKEGN------GVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 + +G+ + I KL +GQ L A+ G K+HAKW P Y Sbjct: 105 --------KSSDGDVKPANPNIPIVKLAEGQRLTFNAYARLGRGKDHAKWQPGFVY---Y 153 Query: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNE-------------------GDPFDY 221 K+ + + + KE + + E+ E G Sbjct: 154 KYLTKIHVSKDVPDWEELKELAERRGLPVEESDEEIVITTIKAFYLPRKFEEHMGKGIRE 213 Query: 222 KAQADTFYMNVESVGSIPVDQVVVRGIDTLQKK 254 + +F VE+ G +PV+++V + L +K Sbjct: 214 EIVPGSFVFTVETNGELPVEEIVSIALKILMRK 246 >6F44-C nrPDB Length = 335 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 73/292 (25%), Positives = 129/292 (44%), Gaps = 52/292 (17%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 +V I +F L N+D ++AN+ RR+MI+E+P++A + V NT+V+ DE +AHR Sbjct: 41 EVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHR 100 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDH--CDKCSVVLTLQAF--------------GESEST 110 +GL+PL+ +D + L + +D D+ ++VL+L E + Sbjct: 101 IGLVPLK-VDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNN 159 Query: 111 TNVYSKDLVIVSNLMGRNIGH----PIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKE 166 +VY++DL GR P++ +L+ KLR GQE+ L GI + Sbjct: 160 AHVYARDLKF--EPQGRQSTTFADCPVV--PADPDILLAKLRPGQEISLKAHCILGIGGD 215 Query: 167 HAKWGPAAAIEFEYDPWNKL------------------------KHTDYWYEQDSAKEWP 202 HAK+ P + + P + + +D Y +D+ K+ Sbjct: 216 HAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTV 275 Query: 203 QSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKK 254 + YE+ D + F NVES G++ +++ + + L+ K Sbjct: 276 SREVLRYEE---FADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNK 324 >5LMX-C nrPDB Length = 380 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 73/292 (25%), Positives = 129/292 (44%), Gaps = 52/292 (17%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 +V I +F L N+D ++AN+ RR+MI+E+P++A + V NT+V+ DE +AHR Sbjct: 41 EVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHR 100 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDH--CDKCSVVLTLQAF--------------GESEST 110 +GL+PL+ +D + L + +D D+ ++VL+L E + Sbjct: 101 IGLVPLK-VDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNN 159 Query: 111 TNVYSKDLVIVSNLMGRNIGH----PIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKE 166 +VY++DL GR P++ +L+ KLR GQE+ L GI + Sbjct: 160 AHVYARDLKF--EPQGRQSTTFADCPVVP--ADPDILLAKLRPGQEISLKAHCILGIGGD 215 Query: 167 HAKWGPAAAIEFEYDPWNKL------------------------KHTDYWYEQDSAKEWP 202 HAK+ P + + P + + +D Y +D+ K+ Sbjct: 216 HAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTV 275 Query: 203 QSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKK 254 + YE+ D + F NVES G++ +++ + + L+ K Sbjct: 276 SREVLRYEE---FADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNK 324 >2PMZ-D nrPDB Length = 265 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 65/265 (24%), Positives = 115/265 (43%), Gaps = 34/265 (12%) Query: 17 NVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMD 76 +D + L N++RR + +P +A+D V N + L DE +AHRL LIP S + Sbjct: 12 RIDLVFEGYPLEFVNAIRRASMLYVPIMAVDDVYFIENNSPLYDEILAHRLALIPFMSEE 71 Query: 77 -IEQLEYSRDCF-CEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPII 134 ++ + +C C ++C+KC + ++A +E +YSKD+ P + Sbjct: 72 ALDTYRWPEECIECTENCEKCYTKIYIEAEAPNEPRM-IYSKDI---------KSEDPSV 121 Query: 135 QDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKL-----KHT 189 G+ + I L Q++ L + G KEHAK+ P + Y P ++ K Sbjct: 122 VPISGD-IPIVLLGTNQKISLEARLRLGYGKEHAKFIPVSLSVVRYYPKVEILANCEKAV 180 Query: 190 DYWYE--------QDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 + E + S K CE E D + + +ESVGS+ + Sbjct: 181 NVCPEGVFELKDGKLSVKNELSCTLCE-ECLRYCNGSIRISFVEDKYILEIESVGSLKPE 239 Query: 242 QV-------VVRGIDTLQKKVASIL 259 ++ ++R I+ L+KK+ ++ Sbjct: 240 RILLEAGKSIIRKIEELEKKLVEVV 264 >2WB1-D nrPDB Length = 265 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 13/168 (7%) Query: 17 NVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMD 76 +D + L N++RR + +P ++ID V N + L DE +AHRL LIP S + Sbjct: 12 RIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRLALIPFTSEE 71 Query: 77 -IEQLEYSRDCF-CEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPII 134 ++ + +C C ++C+KC + ++A +E +YSKD+ P I Sbjct: 72 ALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKM-LYSKDI---------KSEDPSI 121 Query: 135 QDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDP 182 G+ + I L Q++ L + G KEHAK+ P + Y P Sbjct: 122 VPISGD-IPIVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYP 168 >1IW7-A nrPDB Length = 315 Score = 31.6 bits (70), Expect = 0.51, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 30/53 (56%), Gaps = 4/53 (7%) Query: 4 EGPQVKIREASKDNVDFILSNVD----LAMANSLRRVMIAEIPTLAIDSVEVE 52 + P +R ++ +F+L ++ + + N LRR++++ IP A+ SV +E Sbjct: 7 KAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIE 59 >4YUU-B1 nrPDB Length = 509 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 129 IGHPIIQDKEGNGVLICKLRKGQE-LKLTCVAKKGIAK 165 +GHP+ QDKEG+ +++ ++ E + V K GI + Sbjct: 341 LGHPVFQDKEGHELIVRRMPAFFENFPIILVDKDGIIR 378 >1PXZ-A nrPDB Length = 346 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 31/171 (18%), Positives = 67/171 (39%), Gaps = 31/171 (18%) Query: 26 DLAMANSLRRVMIAEIPTLAIDSVEVE-TNTTVLADEFIAHRLGLIPLQSMDIEQLEYSR 84 D+ + N + + ++ + + S+ + NT+VL D ++ +G+ P+ + D + + Sbjct: 98 DVHLGNGGPCLFMRKVSHVILHSLHIHGCNTSVLGDVLVSESIGVEPVHAQDGDAITMRN 157 Query: 85 ------DCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKE 138 D C + +TL + G + S + ++ V++ +GH D + Sbjct: 158 VTNAWIDHNSLSDCSDGLIDVTLGSTGITISNNHFFNHHKVML-------LGHDDTYDDD 210 Query: 139 GNGVLICKLRKGQELKLTCVAKK-----GIAKEHAKWGPAAAIEFEYDPWN 184 + +K+T + G A++G YDPWN Sbjct: 211 ------------KSMKVTVAFNQFGPNAGQRMPRARYGLVHVANNNYDPWN 249 >5XXU-P nrPDB Length = 150 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 103 AFGESESTTNVYSKDLVIVSNLMGRNIG 130 AFGE N + +DLV+V ++G +G Sbjct: 73 AFGEKPEPVNTHLRDLVVVPEMIGSVVG 100 >1HQM-A nrPDB Length = 313 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 24/38 (63%), Gaps = 4/38 (10%) Query: 19 DFILSNVD----LAMANSLRRVMIAEIPTLAIDSVEVE 52 +F+L ++ + + N LRR++++ IP A+ SV +E Sbjct: 22 EFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIE 59 >6B44-C nrPDB Length = 344 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 10/28 (35%), Positives = 17/28 (60%) Query: 175 AIEFEYDPWNKLKHTDYWYEQDSAKEWP 202 A E + DP + L W ++D+++EWP Sbjct: 15 AFERKLDPSDALMSAGAWAQRDASQEWP 42 >5IG1-A nrPDB Length = 344 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 192 WYEQDSAKEWPQSKNCEYEDPPNEGD 217 ++E+D K + Q KNC+Y+ P E D Sbjct: 218 FWEEDHQKLYAQIKNCQYDFPSPEWD 243 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3HOY-C nrPDB 518 e-147 3J0K-C nrPDB 409 e-115 5X4Z-C nrPDB 381 e-106 3H0G-C nrPDB 366 e-102 5IYA-C nrPDB 344 4e-95 2PMZ-D nrPDB 277 5e-75 2WB1-D nrPDB 271 2e-73 5LMX-C nrPDB 265 2e-71 6F44-C nrPDB 264 3e-71 4QIW-D nrPDB 255 1e-68 Sequences not found previously or not previously below threshold: 1IW7-A nrPDB 59 3e-09 5ZX3-A nrPDB 54 1e-07 1HQM-A nrPDB 51 9e-07 6CCE-A nrPDB 49 2e-06 4YLN-A nrPDB 47 1e-05 4MEY-A nrPDB 46 2e-05 2E5V-A nrPDB 31 0.87 3AZZ-A nrPDB 29 2.6 1VHG-A nrPDB 29 3.3 3FHN-A nrPDB 29 3.8 1B1X-A nrPDB 28 5.9 >3HOY-C nrPDB Length = 347 Score = 518 bits (1333), Expect = e-147, Method: Composition-based stats. Identities = 317/317 (100%), Positives = 317/317 (100%) Query: 2 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE 61 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE Sbjct: 31 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADE 90 Query: 62 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 121 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV Sbjct: 91 FIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 150 Query: 122 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 181 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD Sbjct: 151 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 210 Query: 182 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD Sbjct: 211 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 270 Query: 242 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS 301 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS Sbjct: 271 QVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYS 330 Query: 302 NASQMGNTGSGGYDNAW 318 NASQMGNTGSGGYDNAW Sbjct: 331 NASQMGNTGSGGYDNAW 347 >3J0K-C nrPDB Length = 268 Score = 409 bits (1052), Expect = e-115, Method: Composition-based stats. Identities = 268/268 (100%), Positives = 268/268 (100%) Query: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD Sbjct: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 Query: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI 120 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI Sbjct: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI 120 Query: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY Sbjct: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 Query: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV Sbjct: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 Query: 241 DQVVVRGIDTLQKKVASILLALTQMDQD 268 DQVVVRGIDTLQKKVASILLALTQMDQD Sbjct: 241 DQVVVRGIDTLQKKVASILLALTQMDQD 268 >5X4Z-C nrPDB Length = 304 Score = 381 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 155/263 (58%), Positives = 200/263 (76%), Gaps = 2/263 (0%) Query: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 MS+E P+V I A D V+ +LS+V+L++ANSLRR M+AE+PTLAID VE++ NT+VLAD Sbjct: 1 MSKE-PKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLAD 59 Query: 61 EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESE-STTNVYSKDLV 119 EFI+HRLGLIPL S D+E+++YSRDC CED+CD+CSVVL L A E E TT+VYS L+ Sbjct: 60 EFISHRLGLIPLVSEDVEEMKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYSSSLI 119 Query: 120 IVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFE 179 VS N+G P+ +D G+L+CKLR QEL + C+AKKGIAKEHAKW P +AI FE Sbjct: 120 KVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSAIAFE 179 Query: 180 YDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIP 239 YDP NKLKHTD+W+E D+ KEWP SK +E+PP G+ FDYKA+ + FYM VE+ GS+ Sbjct: 180 YDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETTGSLK 239 Query: 240 VDQVVVRGIDTLQKKVASILLAL 262 +QV RGI TLQ+K+A++L L Sbjct: 240 ANQVFSRGIKTLQEKLANVLFEL 262 >3H0G-C nrPDB Length = 297 Score = 366 bits (940), Expect = e-102, Method: Composition-based stats. Identities = 147/276 (53%), Positives = 207/276 (75%), Gaps = 13/276 (4%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ DEF+AHR Sbjct: 6 HITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHR 65 Query: 67 LGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 121 LG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y++DLV+ Sbjct: 66 LGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVS 125 Query: 122 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 181 SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A+ FEYD Sbjct: 126 SN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 Query: 182 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 PWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESVGSIP + Sbjct: 183 PWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPN 242 Query: 242 QVVVRGIDTLQKKVASILLAL-----TQMDQDKVNF 272 +++V+G+ LQ+K+A ++ L TQ+ +++N Sbjct: 243 EIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNM 278 >5IYA-C nrPDB Length = 275 Score = 344 bits (881), Expect = 4e-95, Method: Composition-based stats. Identities = 123/270 (45%), Positives = 172/270 (63%), Gaps = 10/270 (3%) Query: 6 PQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAH 65 P V+I E + +NV FI+ N DLA+ANS+RRV IAE+P +AID V+++ N++VL DEFIAH Sbjct: 7 PTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAH 66 Query: 66 RLGLIPLQSMDI-EQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLV----I 120 RLGLIPL S DI ++L+YSRDC CE+ C +CSV TL + T +V S+DL+ Sbjct: 67 RLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPR 126 Query: 121 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 180 V + RN + E + +LI KLRKGQEL+L AKKG KEHAKW P A + FEY Sbjct: 127 VIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEY 186 Query: 181 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 240 DP N L+HT Y +EWP+S+ E ++ ++ P+D + + FY NVES GS+ Sbjct: 187 DPDNALRHTVY----PKPEEWPKSEYSELDEDESQA-PYDPNGKPERFYYNVESCGSLRP 241 Query: 241 DQVVVRGIDTLQKKVASILLALTQMDQDKV 270 + +V+ + L+KK++ + L+ Q V Sbjct: 242 ETIVLSALSGLKKKLSDLQTQLSHEIQSDV 271 >2PMZ-D nrPDB Length = 265 Score = 277 bits (707), Expect = 5e-75, Method: Composition-based stats. Identities = 65/274 (23%), Positives = 117/274 (42%), Gaps = 34/274 (12%) Query: 8 VKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRL 67 + + +D + L N++RR + +P +A+D V N + L DE +AHRL Sbjct: 3 INLLHKDDTRIDLVFEGYPLEFVNAIRRASMLYVPIMAVDDVYFIENNSPLYDEILAHRL 62 Query: 68 GLIPLQSMD-IEQLEYSRDCF-CEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLM 125 LIP S + ++ + +C C ++C+KC + ++A +E +YSKD+ Sbjct: 63 ALIPFMSEEALDTYRWPEECIECTENCEKCYTKIYIEAEAPNEPRM-IYSKDI------- 114 Query: 126 GRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNK 185 P + G+ + I L Q++ L + G KEHAK+ P + Y P + Sbjct: 115 --KSEDPSVVPISGD-IPIVLLGTNQKISLEARLRLGYGKEHAKFIPVSLSVVRYYPKVE 171 Query: 186 L-----KHTDYWYE--------QDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNV 232 + K + E + S K CE E D + + + Sbjct: 172 ILANCEKAVNVCPEGVFELKDGKLSVKNELSCTLCE-ECLRYCNGSIRISFVEDKYILEI 230 Query: 233 ESVGSIPVDQV-------VVRGIDTLQKKVASIL 259 ESVGS+ +++ ++R I+ L+KK+ ++ Sbjct: 231 ESVGSLKPERILLEAGKSIIRKIEELEKKLVEVV 264 >2WB1-D nrPDB Length = 265 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 66/274 (24%), Positives = 117/274 (42%), Gaps = 34/274 (12%) Query: 8 VKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRL 67 + + +D + L N++RR + +P ++ID V N + L DE +AHRL Sbjct: 3 INLLHKDDKRIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRL 62 Query: 68 GLIPLQSMD-IEQLEYSRDCF-CEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLM 125 LIP S + ++ + +C C ++C+KC + ++A +E +YSKD+ Sbjct: 63 ALIPFTSEEALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKM-LYSKDI------- 114 Query: 126 GRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNK 185 P I G+ + I L Q++ L + G KEHAK+ P + Y P + Sbjct: 115 --KSEDPSIVPISGD-IPIVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYPKVE 171 Query: 186 L-----KHTDYWYE--------QDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNV 232 + K E + S K CE E + D + + + Sbjct: 172 ILGNCEKGATVCPEGVFELKDGKLSVKNELACTLCE-ECLRYCNGLIRISSVEDKYILEL 230 Query: 233 ESVGSIPVDQV-------VVRGIDTLQKKVASIL 259 ESVGS+ +++ ++R I+ L+KK+ ++ Sbjct: 231 ESVGSLKPERILLEAGKSIIRKIEELEKKLVEVI 264 >5LMX-C nrPDB Length = 380 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 72/290 (24%), Positives = 126/290 (43%), Gaps = 48/290 (16%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 +V I +F L N+D ++AN+ RR+MI+E+P++A + V NT+V+ DE +AHR Sbjct: 41 EVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHR 100 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDH--CDKCSVVLTLQAFG--------------ESEST 110 +GL+PL+ +D + L + +D D+ ++VL+L E + Sbjct: 101 IGLVPLK-VDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNN 159 Query: 111 TNVYSKDLVIVSNLMGRNIGHPIIQD--KEGNGVLICKLRKGQELKLTCVAKKGIAKEHA 168 +VY++DL GR +L+ KLR GQE+ L GI +HA Sbjct: 160 AHVYARDLKF--EPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHA 217 Query: 169 KWGPAAAIEFEYDPWNKL------------------------KHTDYWYEQDSAKEWPQS 204 K+ P + + P + + +D Y +D+ K+ Sbjct: 218 KFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSR 277 Query: 205 KNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKK 254 + YE+ D + F NVES G++ +++ + + L+ K Sbjct: 278 EVLRYEE---FADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNK 324 >6F44-C nrPDB Length = 335 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 72/290 (24%), Positives = 126/290 (43%), Gaps = 48/290 (16%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 +V I +F L N+D ++AN+ RR+MI+E+P++A + V NT+V+ DE +AHR Sbjct: 41 EVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHR 100 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDH--CDKCSVVLTLQAFG--------------ESEST 110 +GL+PL+ +D + L + +D D+ ++VL+L E + Sbjct: 101 IGLVPLK-VDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNN 159 Query: 111 TNVYSKDLVIVSNLMGRNIGHPIIQD--KEGNGVLICKLRKGQELKLTCVAKKGIAKEHA 168 +VY++DL GR +L+ KLR GQE+ L GI +HA Sbjct: 160 AHVYARDLKF--EPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHA 217 Query: 169 KWGPAAAIEFEYDPWNKL------------------------KHTDYWYEQDSAKEWPQS 204 K+ P + + P + + +D Y +D+ K+ Sbjct: 218 KFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSR 277 Query: 205 KNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKK 254 + YE+ D + F NVES G++ +++ + + L+ K Sbjct: 278 EVLRYEE---FADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNK 324 >4QIW-D nrPDB Length = 259 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 77/278 (27%), Positives = 118/278 (42%), Gaps = 42/278 (15%) Query: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 + KI E D++ FI+S VD+ AN+LRR +++E+PT A+D VE N + L DE IAHR Sbjct: 3 EFKILEKRPDSIKFIVSGVDVPFANALRRTILSEVPTFAVDEVEFLENDSALFDEIIAHR 62 Query: 67 LGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMG 126 L +IPL + +S D D +V L+L+A E VYS DL Sbjct: 63 LAMIPLTT---PHERFSLDAL---ELDDYTVTLSLEA----EGPGMVYSGDLKSSDGD-- 110 Query: 127 RNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKL 186 + I KL +GQ L A+ G K+HAKW P Y K+ Sbjct: 111 --------VKPANPNIPIVKLAEGQRLTFNAYARLGRGKDHAKWQPGFVY---YKYLTKI 159 Query: 187 KHTDYWYEQDSAKEWPQSKNCEYEDPPNE-------------------GDPFDYKAQADT 227 + + + KE + + E+ E G + + Sbjct: 160 HVSKDVPDWEELKELAERRGLPVEESDEEIVITTIKAFYLPRKFEEHMGKGIREEIVPGS 219 Query: 228 FYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQM 265 F VE+ G +PV+++V + L +K + L ++ Sbjct: 220 FVFTVETNGELPVEEIVSIALKILMRKSDRFINELHKL 257 >1IW7-A nrPDB Length = 315 Score = 59.0 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 90/259 (34%), Gaps = 48/259 (18%) Query: 4 EGPQVKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLA 59 + P +R ++ +F+L + + N LRR++++ IP A+ SV + Sbjct: 7 KAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYI-------- 58 Query: 60 DEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLV 119 E + H IP D+ ++ + + +TL E V ++D + Sbjct: 59 -EDVLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKA--EGPKEVKARDFL 115 Query: 120 IVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFE 179 V+++ N + I L +G L + +G+ Sbjct: 116 PVADVEIMN-----------PDLHIATLEEGGRLNMEVRVDRGVG--------------- 149 Query: 180 YDPWNK--LKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGS 237 Y P K +K D+ P + + G D D + + + GS Sbjct: 150 YVPAEKHGIKDRINAIPVDAVFS-PVRRVAFQVEDTRLGQRTDL----DKLTLRIWTDGS 204 Query: 238 IPVDQVVVRGIDTLQKKVA 256 + + + + ++ L++ + Sbjct: 205 VTPLEALNQAVEILREHLT 223 >5ZX3-A nrPDB Length = 368 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 43/268 (16%), Positives = 86/268 (32%), Gaps = 46/268 (17%) Query: 4 EGPQVKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLA 59 + P + + + F++ + NSLRR +++ IP A+ T++ Sbjct: 26 QRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAV--------TSIRI 77 Query: 60 DEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLV 119 D + H +P D+ ++ + + V + L+ G E V + D+V Sbjct: 78 DGVL-HEFTTVPGVKEDVTEIILNLKSLVVSSEEDEPVTMYLRKQGPGE----VTAGDIV 132 Query: 120 IVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFE 179 P G+ I L +L++ V ++G A A+ E Sbjct: 133 P-----------PAGVTVHNPGMHIATLNDKGKLEVELVVERGRGYVPAVQNRASGAEIG 181 Query: 180 YDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIP 239 P + + K + E + D ++VE+ SI Sbjct: 182 RIPVDSIY-------SPVLKVTYKVDATRVEQRTDF----------DKLILDVETKNSIS 224 Query: 240 VDQVVVRGIDTLQKKVASILLALTQMDQ 267 + TL + + + L + Sbjct: 225 PRDALASAGKTLVE-LFGLARELNVEAE 251 >1HQM-A nrPDB Length = 313 Score = 50.6 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 42/257 (16%), Positives = 87/257 (33%), Gaps = 47/257 (18%) Query: 4 EGPQVKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLA 59 + P +F+L + + N LRR++++ IP A+ SV + Sbjct: 7 KAPVFTATTQGDHYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYI-------- 58 Query: 60 DEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCD-KCSVVLTLQAFGESESTTNVYSKDL 118 E + H IP D+ ++ + D + L L+A E V + D Sbjct: 59 -EDVLHEFSTIPGVKEDVVEIILNLKELVVRFLDPRWRTTLILRA----EGPKEVRAVDF 113 Query: 119 VIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEF 178 +++ N + I L +G +L + +G+ + PA Sbjct: 114 TPSADVEIMN-----------PDLHIATLEEGGKLYMEVRVDRGVG-----YVPAERHGI 157 Query: 179 EYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSI 238 + D N + D + P + + G D D + + + GS+ Sbjct: 158 K-DRINAIP-VDAIFS-------PVRRVAFQVEDTRLGQRTDL----DKLTLRIWTDGSV 204 Query: 239 PVDQVVVRGIDTLQKKV 255 + + + + L++ + Sbjct: 205 TPLEALNQAVAILKEHL 221 >6CCE-A nrPDB Length = 350 Score = 49.0 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 41/268 (15%), Positives = 85/268 (31%), Gaps = 46/268 (17%) Query: 4 EGPQVKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLA 59 + P + +++ F++ + NSLRR +++ IP A+ T++ Sbjct: 5 QRPTLSEETVAENRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAV--------TSIRI 56 Query: 60 DEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLV 119 D + H +P D+ + + D V + L+ + V + D+V Sbjct: 57 DGVL-HEFTTVPGVKEDVTDIILNLKGLVVSSDDDEPVTMYLR----KQGPGVVTAGDIV 111 Query: 120 IVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFE 179 P + I L +L++ V ++G A A+ E Sbjct: 112 P-----------PAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAVQNKASGAEIG 160 Query: 180 YDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIP 239 P + + K + + E + D ++VE+ SI Sbjct: 161 RIPVDSIY-------SPVLKVTYKVEATRVEQRTDF----------DKLIIDVETKNSIS 203 Query: 240 VDQVVVRGIDTLQKKVASILLALTQMDQ 267 + TL + + + L + Sbjct: 204 PRDALASAGGTLVE-LFGLARELNADSE 230 >4YLN-A nrPDB Length = 242 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 37/259 (14%), Positives = 86/259 (33%), Gaps = 47/259 (18%) Query: 8 VKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFI 63 V I + S + L + N+LRR++++ +P A+ VE++ + Sbjct: 21 VDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDG---------V 71 Query: 64 AHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSN 123 H DI ++ + K V+LTL V + D+ Sbjct: 72 LHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLN----KSGIGPVTAADI----- 122 Query: 124 LMGRNIGHPIIQDKEGNGVLICKLR-KGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDP 182 H + +IC L + + + ++G + PA+ Sbjct: 123 ------THDGDVEIVKPQHVICHLTDENASISMRIKVQRGRG-----YVPAS-------- 163 Query: 183 WNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQAD--TFYMNVESVGSIPV 240 ++ + E+ + + E + + + D + +E+ G+I Sbjct: 164 -TRIHSEED--ERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDP 220 Query: 241 DQVVVRGIDTLQKKVASIL 259 ++ + R L +++ + + Sbjct: 221 EEAIRRAATILAEQLEAFV 239 >4MEY-A nrPDB Length = 335 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 40/270 (14%), Positives = 91/270 (33%), Gaps = 48/270 (17%) Query: 8 VKIREASKDNVDFILS----NVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFI 63 V I + S + L + N+LRR++++ +P A+ VE++ + Sbjct: 20 VDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDG---------V 70 Query: 64 AHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSN 123 H DI ++ + K V+LTL V + D+ Sbjct: 71 LHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLN----KSGIGPVTAADI----- 121 Query: 124 LMGRNIGHPIIQDKEGNGVLICKLR-KGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDP 182 H + +IC L + + + ++G + PA+ Sbjct: 122 ------THDGDVEIVKPQHVICHLTDENASISMRIKVQRGRG-----YVPAS-------- 162 Query: 183 WNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQAD--TFYMNVESVGSIPV 240 ++ + E+ + + E + + + D + +E+ G+I Sbjct: 163 -TRIHSEED--ERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDP 219 Query: 241 DQVVVRGIDTLQKKVASILLALTQMDQDKV 270 ++ + R L +++ + + L + Q +V Sbjct: 220 EEAIRRAATILAEQLEAFV-DLRDVRQPEV 248 >2E5V-A nrPDB Length = 472 Score = 30.5 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 23/63 (36%), Gaps = 1/63 (1%) Query: 210 EDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDK 269 E EG + F N + G + ++ R I K + + L++++ + Sbjct: 227 ETLRGEGAQI-INENGERFLFNYDKRGELAPRDILSRAIYIEMLKGHKVFIDLSKIEDFE 285 Query: 270 VNF 272 F Sbjct: 286 RKF 288 >3AZZ-A nrPDB Length = 272 Score = 29.0 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 30/97 (30%), Gaps = 4/97 (4%) Query: 163 IAKEHAKWGPAAA-IEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDY 221 I HAK P E EY + ++ KE + Y+ Sbjct: 32 IGNGHAKGIPGWGNGELEYYTDENAFVENGCLVIEARKEQVSDEYGTYD---YTSARMTT 88 Query: 222 KAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASI 258 + + + Y +E +P + + + L + + Sbjct: 89 EGKFEIKYGKIEIRAKLPKGKGIWPALWMLGNNIGEV 125 >1VHG-A nrPDB Length = 198 Score = 28.6 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%) Query: 2 SEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPT 43 S + P + E + F + +VDL +N +RRV PT Sbjct: 6 SLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPT 47 >3FHN-A nrPDB Length = 706 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 226 DTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLG 285 D+F ++ + P DQ + + L K+ S+ + Q++ +A+ N S + G Sbjct: 101 DSFERQLDELAEQPPDQFTLDDVKALHSKLTSVFATVPQINNIDSQYAAY-NKLKSKVTG 159 Query: 286 SNEDVMM 292 DV++ Sbjct: 160 KYNDVII 166 >1B1X-A nrPDB Length = 689 Score = 27.8 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 31/85 (36%), Gaps = 1/85 (1%) Query: 85 DCFCEDHCDKCSVVLTLQAFGESESTTNV-YSKDLVIVSNLMGRNIGHPIIQDKEGNGVL 143 + C + ++ T +E +V + KD+ ++ N G+N K+ + L Sbjct: 512 ENKCMPNSEERYYGYTGAFRCLAEKAGDVAFVKDVTVLQNTDGKNSEPWAKDLKQEDFEL 571 Query: 144 ICKLRKGQELKLTCVAKKGIAKEHA 168 +C + + A HA Sbjct: 572 LCLDGTRKPVAEAESCHLARAPNHA 596 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.124 0.316 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,856,278 Number of Sequences: 36641 Number of extensions: 399455 Number of successful extensions: 846 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 771 Number of HSP's gapped (non-prelim): 49 length of query: 318 length of database: 10,336,785 effective HSP length: 97 effective length of query: 221 effective length of database: 6,782,608 effective search space: 1498956368 effective search space used: 1498956368 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 59 (27.4 bits)