BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P16278 (677 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3WF0-A nrPDB 1357 0.0 4MAD-A nrPDB 443 e-125 6EON-A nrPDB 371 e-103 3D3A-A nrPDB 367 e-102 4E8C-A nrPDB 329 2e-90 6IK8-B nrPDB 155 6e-38 5GSM-A nrPDB 143 2e-34 5GSL-A nrPDB 132 7e-31 1XC6-A nrPDB 119 5e-27 4D1J-A nrPDB 40 0.002 3U7V-A nrPDB 39 0.006 2VOA-A nrPDB 35 0.12 4UCF-A nrPDB 34 0.21 5YEQ-A nrPDB 33 0.51 5WMM-A nrPDB 32 0.97 5E9A-A nrPDB 31 2.0 3TTS-A nrPDB 30 4.7 5YTK-A nrPDB 29 8.5 >3WF0-A nrPDB Length = 678 Score = 1357 bits (3512), Expect = 0.0, Method: Compositional matrix adjust. Identities = 654/654 (100%), Positives = 654/654 (100%) Query: 24 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY 83 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY Sbjct: 25 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY 84 Query: 84 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE 143 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE Sbjct: 85 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE 144 Query: 144 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL 203 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL Sbjct: 145 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL 204 Query: 204 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP 263 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP Sbjct: 205 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP 264 Query: 264 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP 323 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP Sbjct: 265 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP 324 Query: 324 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK 383 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK Sbjct: 325 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK 384 Query: 384 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA 443 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA Sbjct: 385 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA 444 Query: 444 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS 503 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS Sbjct: 445 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS 504 Query: 504 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP 563 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP Sbjct: 505 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP 564 Query: 564 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW 623 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW Sbjct: 565 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW 624 Query: 624 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV 677 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV Sbjct: 625 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV 678 >4MAD-A nrPDB Length = 600 Score = 443 bits (1140), Expect = e-125, Method: Compositional matrix adjust. Identities = 252/615 (40%), Positives = 356/615 (57%), Gaps = 48/615 (7%) Query: 39 DSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQF 98 DSFL DG+ R +SG++HY R YW+DRLLK+K G N ++TYV WN HEP GQ+ F Sbjct: 22 DSFLLDGKEIRLLSGAMHYFRTVPEYWEDRLLKLKACGFNTVETYVAWNLHEPEEGQFVF 81 Query: 99 SEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAV 158 D+ F++ A ++GL VI+RPGP+ICAEWE GG P WLL +I LR + YL V Sbjct: 82 EGIADIVRFIKTAEKVGLHVIVRPGPFICAEWEFGGFPYWLLTVPNIKLRCFNQPYLEKV 141 Query: 159 DKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLF 218 D + VL +++PLL NGGP+I +Q+ENEYGS F D YL++L+ + +G++ +LF Sbjct: 142 DAYFDVLFERLRPLLSSNGGPIIALQIENEYGS-FGNDQKYLQYLRDGIKKRVGNE-LLF 199 Query: 219 TTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWG 278 T+DG + L G ++G++ TV+F GS AF ++ +P PL+ EF+ GW DHWG Sbjct: 200 TSDGPEPSMLSGGMIEGIFETVNF--GSRAESAFAQLKQYQPNAPLMCMEFWHGWFDHWG 257 Query: 279 QPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGAN---SPYAAQPTSYDYDA 335 + H T E+V +L +IL + SVN YM GGTNF ++NGAN + Y TSYDYD Sbjct: 258 EEHHTRSAESVVETLEEILKQNGSVNFYMAHGGTNFGFYNGANHNETDYQPTITSYDYDG 317 Query: 336 PLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCP- 394 L+E+GD+TEK++A+R + +K+ +PE +P PK +GKV K LD L Sbjct: 318 LLTESGDVTEKFYAVRKVFEKYVDLPELNLPAPIPKRLFGKV---KFTEHAGLLDSLHRI 374 Query: 395 SGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGV 454 S P KS PL + Q YGF++Y TT+ A + +HDR V V+G G+ Sbjct: 375 STPQKSEAPLPMEKYGQAYGFIVYETTIKGAYGKQA---LTVQDIHDRGQVYVNGEYVGI 431 Query: 455 LERN---NVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTI 511 +ERN + + + +T + + L ++VENMGR+NYG ++ D+KG+ + L + L DWT+ Sbjct: 432 VERNRGCSRLVVELT-EEESKLQIIVENMGRINYGPFVVDYKGITEGVRLGNQFLFDWTV 490 Query: 512 FPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFI 571 +PL +D S L + + P F+ G ++ D DTFI Sbjct: 491 YPLPLKDL--SSL-------------EFTADEVKENFPYFHKGILTV-----DKAADTFI 530 Query: 572 QFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDP 631 WTKG V++NG +LGRYW GPQ TL+VP L N I +LEL S Sbjct: 531 DLSEWTKGVVFVNGHHLGRYWEI-GPQQTLYVPAPFLQ-EGENEIILLELHKHHQS---- 584 Query: 632 ELCAVTFVDRPVIGS 646 VTFVD PV+G+ Sbjct: 585 ----VTFVDTPVLGA 595 >6EON-A nrPDB Length = 779 Score = 371 bits (952), Expect = e-103, Method: Compositional matrix adjust. Identities = 228/625 (36%), Positives = 337/625 (53%), Gaps = 54/625 (8%) Query: 11 LLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLL 70 L+LV+ +LG + +++ FE+ +++FL +G+PF + IHY R+P+ YW+ R+ Sbjct: 9 LILVVAVLGSS--CSQSSEGTFEV--GKNTFLLNGEPFVVKAAEIHYPRIPKEYWEHRIK 64 Query: 71 KMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEW 130 K G+N I YV WNFHEP G+Y F+ D+ F RLA E G+ VI+RPGPY+CAEW Sbjct: 65 MCKALGMNTICLYVFWNFHEPEEGRYDFAGQKDIAAFCRLAQENGMYVIVRPGPYVCAEW 124 Query: 131 EMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYG 190 EMGGLP WLL+K+ I LR DP Y+ V +L + ++ L GG +I VQVEN YG Sbjct: 125 EMGGLPWWLLKKKDIKLREQDPYYMERVKLFLNEVGKQLADLQISKGGNIIMVQVENAYG 184 Query: 191 SYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITD 250 + F D Y+ ++ + V LF D + + AL L T++FGTG+NI + Sbjct: 185 A-FGIDKPYISEIRDMVKQAGFTGVPLFQCD--WNSNFENNALDDLLWTINFGTGANIDE 241 Query: 251 AFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIG 310 F ++ P PL+ SEF++GW DHWG H T E + + ++L R S +LYM G Sbjct: 242 QFKRLKELRPDTPLMCSEFWSGWFDHWGAKHETRSAEELVKGMKEMLDRNISFSLYMTHG 301 Query: 311 GTNFAYWNGANSP-YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEG----PI 365 GT+F +W GAN P ++ TSYDYDAP++E+G +T KY +RN++ + +PEG I Sbjct: 302 GTSFGHWGGANFPNFSPTCTSYDYDAPINESGKVTPKYLEVRNLLGNY--LPEGETLPEI 359 Query: 366 PPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQD 425 P S P A + + ++ + L S I+++ Q +G +LYRT+L Sbjct: 360 PDSIPTIAIPTIKMTEMAVLFDNLPHPKESEDIRTMEAF-----DQGWGSILYRTSLSAS 414 Query: 426 CSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER---NNVITLNITGKAGATLDLLVENMGR 482 L + HD A V ++G L R V+ L K G LD+LVE MGR Sbjct: 415 DKEQTLL---ITEAHDWAQVFLNGKKLATLSRLKGEGVVKLPPL-KEGDRLDILVEAMGR 470 Query: 483 VNYGAYINDFKGLVSNLTLSSN----ILTDWTIF--PLDTEDAVRSHLGGWGHRDSGHHD 536 +N+G I D+KG+ + L S+ ++ DW ++ P+D A RD + Sbjct: 471 MNFGKGIYDWKGITEKVELQSDKGVELVKDWQVYTIPVDYSFA----------RDKQYKQ 520 Query: 537 EAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARG 596 + A N PA+Y F++ + DTF+ W+KG VW+NG +GRYW G Sbjct: 521 QENAENQ-----PAYYRSTFNL-----NELGDTFLNMMNWSKGMVWVNGHAIGRYWEI-G 569 Query: 597 PQLTLFVPQHILMTSAPNTITVLEL 621 PQ TL+VP + N I +L++ Sbjct: 570 PQQTLYVP-GCWLKKGENEIIILDM 593 >3D3A-A nrPDB Length = 612 Score = 367 bits (943), Expect = e-102, Method: Compositional matrix adjust. Identities = 224/608 (36%), Positives = 328/608 (53%), Gaps = 52/608 (8%) Query: 28 TQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWN 87 ++ FE+ +++FL +G+PF + IHY R+P+ YW+ R+ K G+N I YV WN Sbjct: 4 SEGTFEV--GKNTFLLNGEPFVVKAAEIHYPRIPKEYWEHRIKMCKALGMNTICLYVFWN 61 Query: 88 FHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILL 147 FHEP G+Y F+ D+ F RLA E G+ VI+RPGPY+CAEWEMGGLP WLL+K+ I L Sbjct: 62 FHEPEEGRYDFAGQKDIAAFCRLAQENGMYVIVRPGPYVCAEWEMGGLPWWLLKKKDIKL 121 Query: 148 RSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRF 207 R DP Y+ V +L + ++ L GG +I VQVENEYG+ F D Y+ ++ Sbjct: 122 REQDPYYMERVKLFLNEVGKQLADLQISKGGNIIMVQVENEYGA-FGIDKPYISEIRDMV 180 Query: 208 RHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINS 267 + V LF D + + AL L T++FGTG+NI + F ++ P PL+ S Sbjct: 181 KQAGFTGVPLFQCD--WNSNFENNALDDLLWTINFGTGANIDEQFKRLKELRPDTPLMCS 238 Query: 268 EFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP-YAA 326 EF++GW DHWG H T E + + ++L R S +LYM GGT+F +W GAN P ++ Sbjct: 239 EFWSGWFDHWGAKHETRSAEELVKGMKEMLDRNISFSLYMTHGGTSFGHWGGANFPNFSP 298 Query: 327 QPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEG----PIPPSTPKFAYGKVTLEKL 382 TSYDYDAP++E+G +T KY +RN++ + +PEG IP S P A + + ++ Sbjct: 299 TCTSYDYDAPINESGKVTPKYLEVRNLLGNY--LPEGETLPEIPDSIPTIAIPTIKMTEM 356 Query: 383 KTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDR 442 + L S I+++ Q +G +LYRT+L L + HD Sbjct: 357 AVLFDNLPHPKESEDIRTMEAFD-----QGWGSILYRTSLSASDKEQTLL---ITEAHDW 408 Query: 443 AYVAVDGIPQGVLER---NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNL 499 A V ++G L R V+ L K G LD+LVE MGR+N+G I D+KG+ + Sbjct: 409 AQVFLNGKKLATLSRLKGEGVVKLPPL-KEGDRLDILVEAMGRMNFGKGIYDWKGITEKV 467 Query: 500 TLSSN----ILTDWTIF--PLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYM 553 L S+ ++ DW ++ P+D A RD + + A N PA+Y Sbjct: 468 ELQSDKGVELVKDWQVYTIPVDYSFA----------RDKQYKQQENAENQ-----PAYYR 512 Query: 554 GNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAP 613 F++ + DTF+ W+KG VW+NG +GRYW GPQ TL+VP + Sbjct: 513 STFNL-----NELGDTFLNMMNWSKGMVWVNGHAIGRYWEI-GPQQTLYVP-GCWLKKGE 565 Query: 614 NTITVLEL 621 N I +L++ Sbjct: 566 NEIIILDM 573 >4E8C-A nrPDB Length = 595 Score = 329 bits (844), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 226/608 (37%), Positives = 328/608 (53%), Gaps = 56/608 (9%) Query: 32 FEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEP 91 FEI RD F DG+ F+ +SG+IHY RVP W L +K G N ++TYV WN HEP Sbjct: 4 FEI---RDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKALGFNTVETYVAWNLHEP 60 Query: 92 WPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSD 151 G++ F D D+E FL++A +LGL I+RP P+ICAEWE GGLPAWLL K ++ +RSSD Sbjct: 61 CEGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFGGLPAWLLTK-NMRIRSSD 119 Query: 152 PDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHL 211 P Y+ AV ++ LLP++ P L NGG ++ +QVENEYGSY D YLR + ++ Sbjct: 120 PAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY-GEDKAYLRAI-RQLMEEC 177 Query: 212 GDDVVLFTTDGAHKTFLKCGAL--QGLYTTVDFGTG-----SNITDAFLSQRKCEPKGPL 264 G LFT+DG + LK G L + L+ T +FG+ S + + F K K PL Sbjct: 178 GVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGK---KWPL 234 Query: 265 INSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPY 324 + EF+ GW + W +P T + +A ++ ++L +G S+NLYMF GGTNF + NG ++ Sbjct: 235 MCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQG-SINLYMFHGGTNFGFMNGCSARG 293 Query: 325 AA---QPTSYDYDAPLSEAGDLTEKYFALRNIIQ-KFEKVPEGPIPPSTPKFAYGKVTLE 380 Q TSYDYDA L E G+ T KY A++ ++ F + P+ P + L Sbjct: 294 TLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYPQLE-PLYKESMELDAIPLV 352 Query: 381 KLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVH 440 + ++ LD L S P++SLYP ++ Q YG++LYRT D ++G Sbjct: 353 EKVSLFETLDSL--SSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEER--LRIIDG-R 407 Query: 441 DRAYVAVDG---IPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYG-AYINDF--KG 494 DRA + VDG Q E I K + LD+L+ENMGRVNYG ++ D KG Sbjct: 408 DRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKG 467 Query: 495 LVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMG 554 + + + + L +W +PL ++ + + W PAFY Sbjct: 468 IRTGVCKDLHFLLNWKHYPLPLDNPEKIDFS-----------KGWTQGQ-----PAFYAY 511 Query: 555 NFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPN 614 +F++ P+DT++ + KG ++NG NLGR+W GP L+L++P H + N Sbjct: 512 DFTVEE-----PKDTYLDLSEFGKGVAFVNGQNLGRFWNV-GPTLSLYIP-HSYLKEGAN 564 Query: 615 TITVLELE 622 I + E E Sbjct: 565 RIIIFETE 572 >6IK8-B nrPDB Length = 718 Score = 155 bits (392), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 110/326 (33%), Positives = 158/326 (48%), Gaps = 19/326 (5%) Query: 32 FEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEP 91 F + Y + + +G+ ISGSIHY R W D + K K GL+ I+TYV WN HEP Sbjct: 6 FSVSYDDRAIIINGKRKILISGSIHYPRSTPQMWPDLIQKAKDGGLDVIETYVFWNGHEP 65 Query: 92 WPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSD 151 PG+Y F +D+ F+++ GL V LR GPY+CAEW GG P WL + R+++ Sbjct: 66 SPGKYNFEGRYDLVRFIKMVQRAGLYVNLRIGPYVCAEWNFGGFPVWLKYVPGMEFRTNN 125 Query: 152 PDYLAAVDKWLGVLLPKMKP--LLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRH 209 + A+ ++ ++ MK L GGP+I Q+EN YG +++ + K + Sbjct: 126 QPFKVAMQGFVQKIVNMMKSENLFESQGGPIIMAQIENAYG---PVEWE-IGAPGKAYTK 181 Query: 210 HLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEF 269 V T ++ C +D G + F R +P P + +E Sbjct: 182 WAAQMAVGLKTG---VPWIMCKQEDAPDPVIDTCNGF-YCEGF---RPNKPYKPKMWTEV 234 Query: 270 YTGWLDHWGQPHSTIKTEAVASSLYDILA-RGASVNLYMFIGGTNFAYWNGANSPYAAQP 328 +TGW +G P E +A S+ + G+ N YM+ GGTNF G S Sbjct: 235 WTGWYTKFGGPIPQRPAEDIAFSVARFVQNNGSFFNYYMYHGGTNF----GRTSSGLFIA 290 Query: 329 TSYDYDAPLSEAGDLTE-KYFALRNI 353 TSYDYDAPL E G L E KY LR++ Sbjct: 291 TSYDYDAPLDEYGLLNEPKYGHLRDL 316 Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 4/44 (9%) Query: 551 FYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPA 594 +Y F+ P G L D KGQ+WING +GR+WP Sbjct: 601 WYKATFNAPGGNDPLALD----MASMGKGQIWINGEGVGRHWPG 640 >5GSM-A nrPDB Length = 786 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 73/179 (40%), Positives = 104/179 (58%), Gaps = 21/179 (11%) Query: 31 MFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHE 90 M ++++S ++ DG+P G++ + RVP WKDRLLKM+ AGLN + TYV WN+HE Sbjct: 1 MGKVEFSGKRYVIDGEPVTIAGGTLQFFRVPADAWKDRLLKMREAGLNTVDTYVAWNWHE 60 Query: 91 PWPGQYQFS-EDH---DVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESIL 146 P G + F E H ++ FL LA ELG VI+RPGPYIC EW GG+P WL+++ + Sbjct: 61 PEKGSFDFKGETHPQRNLVGFLELADELGFYVIIRPGPYICGEWRNGGIPDWLIDEHPEI 120 Query: 147 LRSS-----------------DPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENE 188 L P YL AV +W + P ++ LY NGGP+I+V +++E Sbjct: 121 LAKGPNGPLPRDIYYPPITYLHPTYLEAVGEWYNAVFPVIRKYLYTNGGPIISVSIDDE 179 >5GSL-A nrPDB Length = 778 Score = 132 bits (331), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 69/157 (43%), Positives = 93/157 (59%), Gaps = 21/157 (13%) Query: 53 GSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFS-EDH---DVEYFL 108 G++ Y RVPR YW+DRL KMK GLN ++TY+ WN+HEP G + F+ E H D+ FL Sbjct: 25 GTLQYFRVPRNYWEDRLRKMKSHGLNTVETYIAWNWHEPQEGVFDFTGETHPQRDLIGFL 84 Query: 109 RLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSS-----------------D 151 LA +LGL VI+RPGPYIC EW+ GG+P WL+ +L S Sbjct: 85 ELAQKLGLYVIIRPGPYICGEWKNGGIPDWLINSHPEILAKSPNGSFPRDVYYPPITYLH 144 Query: 152 PDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENE 188 P YL KW +LP ++ LY NGG +I+V +++E Sbjct: 145 PTYLEYAMKWYEEVLPIIRDYLYSNGGSIISVTIDDE 181 >1XC6-A nrPDB Length = 971 Score = 119 bits (297), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 104/360 (28%), Positives = 151/360 (41%), Gaps = 40/360 (11%) Query: 34 IDYSRDSFLKDGQPFRYISGSIHYSRVP-RFYWKDRLLKMKMAGLNAIQTYVPWNFHEPW 92 + + S +G+ SG +H R+P + D K+K G N + YV W E Sbjct: 6 VTWDEHSIFVNGERLMIFSGEVHPYRLPVASLYIDIFEKVKALGFNCVSFYVDWALLEGN 65 Query: 93 PGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDP 152 PG Y D++ F A E G+ ++ RPGPYI AE GG P WL + I LR+SD Sbjct: 66 PGHYSAEGIFDLQPFFDAAKEAGIYLLARPGPYINAEVSGGGFPGWLQRVDGI-LRTSDE 124 Query: 153 DYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFAC-------DFDYLRFLQK 205 YL A D + + + NGGP+I Q ENEY AC D Y+++++ Sbjct: 125 AYLKATDNYASNIAATIAKAQITNGGPIILYQPENEYSG--ACCGYNGFPDGSYMQYIED 182 Query: 206 RFRHHLGDDVVLFTTD----GAHKTFLKCGALQGLYTTVDFGTG-----------SNITD 250 R G V + D G + GA+ +Y + G N+ Sbjct: 183 HAR-DAGIVVPFISNDAWAAGHNAPGTGAGAVD-IYGHDSYPLGFDCANPSTWPSGNLPT 240 Query: 251 AF-LSQRKCEPKGPLINSEFYTGWLDHWG----QPHSTIKTEAVASSLY--DILARGASV 303 F S + P P EF G D WG + + Y D A + Sbjct: 241 YFHTSHEQQSPSTPYSLVEFQGGAFDPWGGVGFAKCAALLNHEFERVFYKNDFSFGVAFL 300 Query: 304 NLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEG 363 NLYM GGTN+ N + TSYDY + +SE+ ++T + ++ ++ F KV G Sbjct: 301 NLYMIFGGTNW-----GNLGHPGGYTSYDYGSAISESRNITREKYSELKLLGNFAKVSPG 355 Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 574 PGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPN 614 P + Q+++NG+ G+Y GPQ + VP+ IL N Sbjct: 882 PAAYRVQLYVNGYQYGKYVNNIGPQTSFPVPEGILNYHGTN 922 >4D1J-A nrPDB Length = 540 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 28/196 (14%) Query: 38 RDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ 97 + + + DG P+ + + S KD M+ G N + V W EP GQ+ Sbjct: 13 KHALMVDGAPYIILGSQTNNSSNYPDALKDVWPSMEKMGANTLSIPVAWEQIEPVEGQFD 72 Query: 98 FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGG---LPAW----------LLEKES 144 FS V+ L+ A + + ++L A W+ PAW +++++ Sbjct: 73 FSF---VDVLLKEARQRKVRLVL----LWFATWKNNAPHYAPAWVKLDNARFPRVVKEDG 125 Query: 145 ILLRSSDP---DYLAAVDKWLGVLLPKMKPLLYQNGG-PVITVQVENEYGSYFACDFDYL 200 L S P + LAA K + MK L ++ VI VQV+NE G+Y A DY Sbjct: 126 DTLNSLSPLGQNTLAADKK---AFVELMKYLAKRDKDHTVIMVQVQNEVGTYGAVR-DYS 181 Query: 201 RFLQKRFRHHLGDDVV 216 Q F + DD++ Sbjct: 182 PMAQAVFNAAVPDDLI 197 >3U7V-A nrPDB Length = 552 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 24/171 (14%) Query: 38 RDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLK----MKMAGLNAIQTYVPWNFHEPWP 93 R + + DG PF ++ ++ S W ++ K ++ G N +Q + W EP Sbjct: 48 RHALMVDGAPFLMLAAQVNNSSA----WPSQMAKVWPAIEKVGANTVQVPIAWEQIEPVE 103 Query: 94 GQYQFSEDHDVEYFLRLAHELGLLVIL-------RPGPYICAEW---EMGGLPAWLLEKE 143 GQ+ FS ++ L A E + ++L P EW + P L++ + Sbjct: 104 GQFDFSY---LDLLLEQARERKVRLVLLWFGTWKNSSPSYAPEWVKLDDKRFPR-LIKDD 159 Query: 144 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGG--PVITVQVENEYGSY 192 S P + +D + M L ++ VI VQVENE G+Y Sbjct: 160 GERSYSMSPLAKSTLDADRKAFVALMTHLKAKDAAQKTVIMVQVENETGTY 210 >2VOA-A nrPDB Length = 257 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 66 KDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPY 125 +DRL++ K+AG++ I TYVP F + +YQ+ +++ RL H L V R Sbjct: 88 EDRLIRAKIAGIDVINTYVPQGF-KIDSEKYQYK----LQWLERLYHYLQKTVDFRSFAV 142 Query: 126 ICAEWEMGGLP 136 C + + P Sbjct: 143 WCGDMNVAPEP 153 >4UCF-A nrPDB Length = 689 Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust. Identities = 41/179 (22%), Positives = 66/179 (36%), Gaps = 26/179 (14%) Query: 42 LKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYV-PWNFHEPWPGQYQFSE 100 LK + + G + + P W D + MK AG+N + + W EP G+Y F Sbjct: 13 LKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDF-- 70 Query: 101 DHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILL---RSSDPDYLAA 157 ++ R +LG + G + P WL + +L D + A Sbjct: 71 ----DWLDRAIDKLG-----KAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGA 121 Query: 158 VDKW---------LGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDF--DYLRFLQK 205 + W + L + Y+ V+ V NEYG + D+ D +R QK Sbjct: 122 REHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQK 180 >5YEQ-A nrPDB Length = 340 Score = 32.7 bits (73), Expect = 0.51, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 13/84 (15%) Query: 230 CGALQGLYTTVDFG---TGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIK- 285 G L + T +G G + D + +R + + + +F W++ +G+ +TIK Sbjct: 245 SGMLTAVSDTAKYGGMTVGKMVIDESVKERMKKALDNIRSGKFAEKWVEEYGKGANTIKE 304 Query: 286 ---------TEAVASSLYDILARG 300 E V SL DI+ RG Sbjct: 305 GMKEVDNSTEEKVGRSLRDIILRG 328 >5WMM-A nrPDB Length = 926 Score = 32.0 bits (71), Expect = 0.97, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 12/85 (14%) Query: 381 KLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYG-------FVLYRTTLPQDCSNPAPLS 433 +++ V A D+L P+ + + + V YG YR + P C +P P+ Sbjct: 295 QVREVWAGGDVLSPAAVRRLVRDDGTLTVVNGYGPTETTTFAARYRMSAPARCKDPLPIG 354 Query: 434 SPLNGVHDRAYVAVD---GIPQGVL 455 P+ G R Y D +PQGV+ Sbjct: 355 EPMAG--SRLYALDDRLRQVPQGVI 377 >5E9A-A nrPDB Length = 712 Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust. Identities = 38/143 (26%), Positives = 51/143 (35%), Gaps = 34/143 (23%) Query: 72 MKMAGLNAIQTYV-PWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEW 130 MK A N + + W+ EP G+Y F ++ L HE G+ V L Sbjct: 64 MKEARCNVMSVGIFSWSALEPEEGRYTFDW---MDQVLNRLHENGISVFLAT-------- 112 Query: 131 EMGGLPAWLLEKESILLR-----------------SSDPDYLAAVDKWLGVLLPKMKPLL 173 G PAW+ +K +LR S P Y V G L + Sbjct: 113 PSGARPAWMSQKYPQVLRVGRDRVPALHGGRHNHCMSSPVYREKVQLMNGQLAKR----- 167 Query: 174 YQNGGPVITVQVENEYGSYFACD 196 Y + VI + NEYG CD Sbjct: 168 YAHHPAVIGWHISNEYGGECHCD 190 >3TTS-A nrPDB Length = 675 Score = 29.6 bits (65), Expect = 4.7, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 42/106 (39%), Gaps = 25/106 (23%) Query: 119 ILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLG--------------- 163 + + Y+C G PAW+ +K +LR DY K+ G Sbjct: 69 LTKENIYLCLATSTGAHPAWMAKKYPDVLRV---DYEGRKRKFGGRHNSCPNSPTYRKYA 125 Query: 164 -VLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFR 208 +L K+ Y++ ++ V NEYG Y CD +K+FR Sbjct: 126 KILAGKLAER-YKDHPQIVMWHVSNEYGGYCYCD-----NCEKQFR 165 >5YTK-A nrPDB Length = 274 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 13/47 (27%) Query: 84 VPWNFHEP----------WPGQYQFSEDHDVEYFLRLAHELGLLVIL 120 +P+ FH P +PG Y+ + H YFLRL H+ GLL+ L Sbjct: 62 LPFFFHNPKPFFTLAKELYPGNYKPNVTH---YFLRLLHDKGLLLRL 105 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3WF0-A nrPDB 1018 0.0 4MAD-A nrPDB 785 0.0 6EON-A nrPDB 776 0.0 3D3A-A nrPDB 754 0.0 4E8C-A nrPDB 700 0.0 6IK8-B nrPDB 396 e-110 1XC6-A nrPDB 373 e-103 5GSM-A nrPDB 230 1e-60 5GSL-A nrPDB 224 9e-59 Sequences not found previously or not previously below threshold: 4D1J-A nrPDB 54 2e-07 4UCF-A nrPDB 53 3e-07 3U7V-A nrPDB 52 7e-07 5E9A-A nrPDB 52 8e-07 4OJY-A nrPDB 46 5e-05 3TTS-A nrPDB 46 6e-05 5XB7-A nrPDB 44 3e-04 4R27-A nrPDB 37 0.022 5T9G-A nrPDB 35 0.074 1KWK-A nrPDB 35 0.079 1OHW-A nrPDB 35 0.098 4W8B-A nrPDB 35 0.11 6HA9-A nrPDB 35 0.14 5DT5-A nrPDB 34 0.22 2OC2-A nrPDB 34 0.29 3VDH-A nrPDB 33 0.53 5J7Z-A nrPDB 32 0.62 5T99-A nrPDB 32 0.70 4R30-A nrPDB 32 0.77 3NDZ-A nrPDB 32 0.79 1D9K-B nrPDB 32 0.91 1VFF-A nrPDB 32 0.92 3GM8-A nrPDB 32 1.0 4NHU-B nrPDB 32 1.1 1OTJ-A nrPDB 31 1.6 4RKK-A nrPDB 31 1.6 1VA6-A nrPDB 31 1.8 2OYK-A nrPDB 30 4.0 4HZ6-A nrPDB 29 5.0 5G56-A nrPDB 29 5.1 4OVQ-A nrPDB 29 5.3 5LA1-A nrPDB 29 6.4 >3WF0-A nrPDB Length = 678 Score = 1018 bits (2633), Expect = 0.0, Method: Composition-based stats. Identities = 654/654 (100%), Positives = 654/654 (100%) Query: 24 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY 83 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY Sbjct: 25 LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY 84 Query: 84 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE 143 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE Sbjct: 85 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE 144 Query: 144 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL 203 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL Sbjct: 145 SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL 204 Query: 204 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP 263 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP Sbjct: 205 QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP 264 Query: 264 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP 323 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP Sbjct: 265 LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP 324 Query: 324 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK 383 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK Sbjct: 325 YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK 384 Query: 384 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA 443 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA Sbjct: 385 TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA 444 Query: 444 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS 503 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS Sbjct: 445 YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS 504 Query: 504 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP 563 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP Sbjct: 505 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP 564 Query: 564 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW 623 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW Sbjct: 565 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW 624 Query: 624 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV 677 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV Sbjct: 625 APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV 678 >4MAD-A nrPDB Length = 600 Score = 785 bits (2026), Expect = 0.0, Method: Composition-based stats. Identities = 252/623 (40%), Positives = 358/623 (57%), Gaps = 49/623 (7%) Query: 31 MFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHE 90 M ++ Y DSFL DG+ R +SG++HY R YW+DRLLK+K G N ++TYV WN HE Sbjct: 15 MSQLTYD-DSFLLDGKEIRLLSGAMHYFRTVPEYWEDRLLKLKACGFNTVETYVAWNLHE 73 Query: 91 PWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSS 150 P GQ+ F D+ F++ A ++GL VI+RPGP+ICAEWE GG P WLL +I LR Sbjct: 74 PEEGQFVFEGIADIVRFIKTAEKVGLHVIVRPGPFICAEWEFGGFPYWLLTVPNIKLRCF 133 Query: 151 DPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHH 210 + YL VD + VL +++PLL NGGP+I +Q+ENEYGS F D YL++L+ + Sbjct: 134 NQPYLEKVDAYFDVLFERLRPLLSSNGGPIIALQIENEYGS-FGNDQKYLQYLRDGIKKR 192 Query: 211 LGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFY 270 +G++ +LFT+DG + L G ++G++ TV+F GS AF ++ +P PL+ EF+ Sbjct: 193 VGNE-LLFTSDGPEPSMLSGGMIEGIFETVNF--GSRAESAFAQLKQYQPNAPLMCMEFW 249 Query: 271 TGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGAN---SPYAAQ 327 GW DHWG+ H T E+V +L +IL + SVN YM GGTNF ++NGAN + Y Sbjct: 250 HGWFDHWGEEHHTRSAESVVETLEEILKQNGSVNFYMAHGGTNFGFYNGANHNETDYQPT 309 Query: 328 PTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGA 387 TSYDYD L+E+GD+TEK++A+R + +K+ +PE +P PK +GKV K Sbjct: 310 ITSYDYDGLLTESGDVTEKFYAVRKVFEKYVDLPELNLPAPIPKRLFGKV---KFTEHAG 366 Query: 388 ALDILCP-SGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVA 446 LD L S P KS PL + Q YGF++Y TT+ A + +HDR V Sbjct: 367 LLDSLHRISTPQKSEAPLPMEKYGQAYGFIVYETTIKGAYGKQAL---TVQDIHDRGQVY 423 Query: 447 VDGIPQGVLERN---NVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS 503 V+G G++ERN + + + +T + + L ++VENMGR+NYG ++ D+KG+ + L + Sbjct: 424 VNGEYVGIVERNRGCSRLVVELT-EEESKLQIIVENMGRINYGPFVVDYKGITEGVRLGN 482 Query: 504 NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP 563 L DWT++PL +D + + P F+ G ++ Sbjct: 483 QFLFDWTVYPLPLKDLSSL---------------EFTADEVKENFPYFHKGILTV----- 522 Query: 564 DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW 623 D DTFI WTKG V++NG +LGRYW GPQ TL+VP L N I +LEL Sbjct: 523 DKAADTFIDLSEWTKGVVFVNGHHLGRYWEI-GPQQTLYVPAPFLQ-EGENEIILLELHK 580 Query: 624 APCSSDDPELCAVTFVDRPVIGS 646 S VTFVD PV+G+ Sbjct: 581 HHQS--------VTFVDTPVLGA 595 >6EON-A nrPDB Length = 779 Score = 776 bits (2003), Expect = 0.0, Method: Composition-based stats. Identities = 228/625 (36%), Positives = 337/625 (53%), Gaps = 54/625 (8%) Query: 11 LLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLL 70 L+LV+ +LG + +++ FE+ +++FL +G+PF + IHY R+P+ YW+ R+ Sbjct: 9 LILVVAVLGSS--CSQSSEGTFEV--GKNTFLLNGEPFVVKAAEIHYPRIPKEYWEHRIK 64 Query: 71 KMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEW 130 K G+N I YV WNFHEP G+Y F+ D+ F RLA E G+ VI+RPGPY+CAEW Sbjct: 65 MCKALGMNTICLYVFWNFHEPEEGRYDFAGQKDIAAFCRLAQENGMYVIVRPGPYVCAEW 124 Query: 131 EMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYG 190 EMGGLP WLL+K+ I LR DP Y+ V +L + ++ L GG +I VQVEN YG Sbjct: 125 EMGGLPWWLLKKKDIKLREQDPYYMERVKLFLNEVGKQLADLQISKGGNIIMVQVENAYG 184 Query: 191 SYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITD 250 + F D Y+ ++ + V LF D + + AL L T++FGTG+NI + Sbjct: 185 A-FGIDKPYISEIRDMVKQAGFTGVPLFQCD--WNSNFENNALDDLLWTINFGTGANIDE 241 Query: 251 AFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIG 310 F ++ P PL+ SEF++GW DHWG H T E + + ++L R S +LYM G Sbjct: 242 QFKRLKELRPDTPLMCSEFWSGWFDHWGAKHETRSAEELVKGMKEMLDRNISFSLYMTHG 301 Query: 311 GTNFAYWNGANSP-YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEG----PI 365 GT+F +W GAN P ++ TSYDYDAP++E+G +T KY +RN++ + +PEG I Sbjct: 302 GTSFGHWGGANFPNFSPTCTSYDYDAPINESGKVTPKYLEVRNLLGNY--LPEGETLPEI 359 Query: 366 PPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQD 425 P S P A + + ++ + L S I+++ Q +G +LYRT+L Sbjct: 360 PDSIPTIAIPTIKMTEMAVLFDNLPHPKESEDIRTMEAF-----DQGWGSILYRTSLSAS 414 Query: 426 CSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER---NNVITLNITGKAGATLDLLVENMGR 482 L + HD A V ++G L R V+ L K G LD+LVE MGR Sbjct: 415 DKEQTLL---ITEAHDWAQVFLNGKKLATLSRLKGEGVVKLPPL-KEGDRLDILVEAMGR 470 Query: 483 VNYGAYINDFKGLVSNLTLSSN----ILTDWTIF--PLDTEDAVRSHLGGWGHRDSGHHD 536 +N+G I D+KG+ + L S+ ++ DW ++ P+D A RD + Sbjct: 471 MNFGKGIYDWKGITEKVELQSDKGVELVKDWQVYTIPVDYSFA----------RDKQYKQ 520 Query: 537 EAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARG 596 + A N PA+Y F++ + DTF+ W+KG VW+NG +GRYW G Sbjct: 521 QENAENQ-----PAYYRSTFNL-----NELGDTFLNMMNWSKGMVWVNGHAIGRYWEI-G 569 Query: 597 PQLTLFVPQHILMTSAPNTITVLEL 621 PQ TL+VP + N I +L++ Sbjct: 570 PQQTLYVP-GCWLKKGENEIIILDM 593 >3D3A-A nrPDB Length = 612 Score = 754 bits (1946), Expect = 0.0, Method: Composition-based stats. Identities = 224/608 (36%), Positives = 328/608 (53%), Gaps = 52/608 (8%) Query: 28 TQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWN 87 ++ FE+ +++FL +G+PF + IHY R+P+ YW+ R+ K G+N I YV WN Sbjct: 4 SEGTFEV--GKNTFLLNGEPFVVKAAEIHYPRIPKEYWEHRIKMCKALGMNTICLYVFWN 61 Query: 88 FHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILL 147 FHEP G+Y F+ D+ F RLA E G+ VI+RPGPY+CAEWEMGGLP WLL+K+ I L Sbjct: 62 FHEPEEGRYDFAGQKDIAAFCRLAQENGMYVIVRPGPYVCAEWEMGGLPWWLLKKKDIKL 121 Query: 148 RSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRF 207 R DP Y+ V +L + ++ L GG +I VQVENEYG+ F D Y+ ++ Sbjct: 122 REQDPYYMERVKLFLNEVGKQLADLQISKGGNIIMVQVENEYGA-FGIDKPYISEIRDMV 180 Query: 208 RHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINS 267 + V LF D + + AL L T++FGTG+NI + F ++ P PL+ S Sbjct: 181 KQAGFTGVPLFQCD--WNSNFENNALDDLLWTINFGTGANIDEQFKRLKELRPDTPLMCS 238 Query: 268 EFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP-YAA 326 EF++GW DHWG H T E + + ++L R S +LYM GGT+F +W GAN P ++ Sbjct: 239 EFWSGWFDHWGAKHETRSAEELVKGMKEMLDRNISFSLYMTHGGTSFGHWGGANFPNFSP 298 Query: 327 QPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEG----PIPPSTPKFAYGKVTLEKL 382 TSYDYDAP++E+G +T KY +RN++ + +PEG IP S P A + + ++ Sbjct: 299 TCTSYDYDAPINESGKVTPKYLEVRNLLGNY--LPEGETLPEIPDSIPTIAIPTIKMTEM 356 Query: 383 KTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDR 442 + L S I+++ Q +G +LYRT+L L + HD Sbjct: 357 AVLFDNLPHPKESEDIRTMEAF-----DQGWGSILYRTSLSASDKEQTLL---ITEAHDW 408 Query: 443 AYVAVDGIPQGVLER---NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNL 499 A V ++G L R V+ L K G LD+LVE MGR+N+G I D+KG+ + Sbjct: 409 AQVFLNGKKLATLSRLKGEGVVKLPPL-KEGDRLDILVEAMGRMNFGKGIYDWKGITEKV 467 Query: 500 TLSSN----ILTDWTIF--PLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYM 553 L S+ ++ DW ++ P+D A RD + + A N PA+Y Sbjct: 468 ELQSDKGVELVKDWQVYTIPVDYSFA----------RDKQYKQQENAENQ-----PAYYR 512 Query: 554 GNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAP 613 F++ + DTF+ W+KG VW+NG +GRYW GPQ TL+VP + Sbjct: 513 STFNL-----NELGDTFLNMMNWSKGMVWVNGHAIGRYWEI-GPQQTLYVP-GCWLKKGE 565 Query: 614 NTITVLEL 621 N I +L++ Sbjct: 566 NEIIILDM 573 >4E8C-A nrPDB Length = 595 Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats. Identities = 223/602 (37%), Positives = 325/602 (53%), Gaps = 53/602 (8%) Query: 38 RDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ 97 RD F DG+ F+ +SG+IHY RVP W L +K G N ++TYV WN HEP G++ Sbjct: 7 RDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKALGFNTVETYVAWNLHEPCEGEFH 66 Query: 98 FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAA 157 F D D+E FL++A +LGL I+RP P+ICAEWE GGLPAWLL K ++ +RSSDP Y+ A Sbjct: 67 FEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFGGLPAWLLTK-NMRIRSSDPAYIEA 125 Query: 158 VDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVL 217 V ++ LLP++ P L NGG ++ +QVENEYGSY D YLR ++ + G L Sbjct: 126 VGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY-GEDKAYLRAIR-QLMEECGVTCPL 183 Query: 218 FTTDGAHKTFLKCGAL--QGLYTTVDFGTG-----SNITDAFLSQRKCEPKGPLINSEFY 270 FT+DG + LK G L + L+ T +FG+ S + + F K K PL+ EF+ Sbjct: 184 FTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGK---KWPLMCMEFW 240 Query: 271 TGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYA---AQ 327 GW + W +P T + +A ++ ++L +G S+NLYMF GGTNF + NG ++ Q Sbjct: 241 DGWFNRWKEPIITRDPKELADAVREVLEQG-SINLYMFHGGTNFGFMNGCSARGTLDLPQ 299 Query: 328 PTSYDYDAPLSEAGDLTEKYFALRNIIQ-KFEKVPEGPIPPSTPKFAYGKVTLEKLKTVG 386 TSYDYDA L E G+ T KY A++ ++ F + P+ P + L + ++ Sbjct: 300 VTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYPQLE-PLYKESMELDAIPLVEKVSLF 358 Query: 387 AALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVA 446 LD L S P++SLYP ++ Q YG++LYRT D ++G DRA + Sbjct: 359 ETLDSL--SSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEERL--RIIDG-RDRAQLY 413 Query: 447 VDG---IPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYG-AYINDF--KGLVSNLT 500 VDG Q E I K + LD+L+ENMGRVNYG ++ D KG+ + + Sbjct: 414 VDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVC 473 Query: 501 LSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPS 560 + L +W +PL ++ + + W PAFY +F++ Sbjct: 474 KDLHFLLNWKHYPLPLDNPEKIDFS-----------KGWTQGQ-----PAFYAYDFTVEE 517 Query: 561 GIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLE 620 P+DT++ + KG ++NG NLGR+W GP L+L++P H + N I + E Sbjct: 518 -----PKDTYLDLSEFGKGVAFVNGQNLGRFWNV-GPTLSLYIP-HSYLKEGANRIIIFE 570 Query: 621 LE 622 E Sbjct: 571 TE 572 >6IK8-B nrPDB Length = 718 Score = 396 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 110/330 (33%), Positives = 159/330 (48%), Gaps = 19/330 (5%) Query: 28 TQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWN 87 + F + Y + + +G+ ISGSIHY R W D + K K GL+ I+TYV WN Sbjct: 2 AEAEFSVSYDDRAIIINGKRKILISGSIHYPRSTPQMWPDLIQKAKDGGLDVIETYVFWN 61 Query: 88 FHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILL 147 HEP PG+Y F +D+ F+++ GL V LR GPY+CAEW GG P WL + Sbjct: 62 GHEPSPGKYNFEGRYDLVRFIKMVQRAGLYVNLRIGPYVCAEWNFGGFPVWLKYVPGMEF 121 Query: 148 RSSDPDYLAAVDKWLGVLLPKMKP--LLYQNGGPVITVQVENEYGSYFACDFDYLRFLQK 205 R+++ + A+ ++ ++ MK L GGP+I Q+EN YG +++ + K Sbjct: 122 RTNNQPFKVAMQGFVQKIVNMMKSENLFESQGGPIIMAQIENAYG---PVEWE-IGAPGK 177 Query: 206 RFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLI 265 + V T ++ C +D G + F R +P P + Sbjct: 178 AYTKWAAQMAVGLKTG---VPWIMCKQEDAPDPVIDTCNGF-YCEGF---RPNKPYKPKM 230 Query: 266 NSEFYTGWLDHWGQPHSTIKTEAVASSLYDILAR-GASVNLYMFIGGTNFAYWNGANSPY 324 +E +TGW +G P E +A S+ + G+ N YM+ GGTNF G S Sbjct: 231 WTEVWTGWYTKFGGPIPQRPAEDIAFSVARFVQNNGSFFNYYMYHGGTNF----GRTSSG 286 Query: 325 AAQPTSYDYDAPLSEAGDLTE-KYFALRNI 353 TSYDYDAPL E G L E KY LR++ Sbjct: 287 LFIATSYDYDAPLDEYGLLNEPKYGHLRDL 316 >1XC6-A nrPDB Length = 971 Score = 373 bits (958), Expect = e-103, Method: Composition-based stats. Identities = 113/424 (26%), Positives = 169/424 (39%), Gaps = 42/424 (9%) Query: 34 IDYSRDSFLKDGQPFRYISGSIHYSRVP-RFYWKDRLLKMKMAGLNAIQTYVPWNFHEPW 92 + + S +G+ SG +H R+P + D K+K G N + YV W E Sbjct: 6 VTWDEHSIFVNGERLMIFSGEVHPYRLPVASLYIDIFEKVKALGFNCVSFYVDWALLEGN 65 Query: 93 PGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDP 152 PG Y D++ F A E G+ ++ RPGPYI AE GG P WL + I LR+SD Sbjct: 66 PGHYSAEGIFDLQPFFDAAKEAGIYLLARPGPYINAEVSGGGFPGWLQRVDGI-LRTSDE 124 Query: 153 DYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSY------FACDFDYLRFLQKR 206 YL A D + + + NGGP+I Q ENEY F D Y+++++ Sbjct: 125 AYLKATDNYASNIAATIAKAQITNGGPIILYQPENEYSGACCGYNGFP-DGSYMQYIEDH 183 Query: 207 FRHHLGDDVVLFTTD----GAHKTFLKCGALQGLYTTVDFGTG-----------SNITDA 251 R G V + D G + GA+ +Y + G N+ Sbjct: 184 AR-DAGIVVPFISNDAWAAGHNAPGTGAGAVD-IYGHDSYPLGFDCANPSTWPSGNLPTY 241 Query: 252 F-LSQRKCEPKGPLINSEFYTGWLDHWG----QPHSTIKTEAVASSLY--DILARGASVN 304 F S + P P EF G D WG + + Y D A +N Sbjct: 242 FHTSHEQQSPSTPYSLVEFQGGAFDPWGGVGFAKCAALLNHEFERVFYKNDFSFGVAFLN 301 Query: 305 LYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGP 364 LYM GGTN+ N + TSYDY + +SE+ ++T + ++ ++ F KV G Sbjct: 302 LYMIFGGTNWG-----NLGHPGGYTSYDYGSAISESRNITREKYSELKLLGNFAKVSPGY 356 Query: 365 IPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQ 424 + + + T TV +L + S + + V Y+ T+P Sbjct: 357 LVANPGDLSTSTYTNTADLTV---TPLLGSNSSASSFFVIRHSDY-SSQASVEYKLTVPT 412 Query: 425 DCSN 428 N Sbjct: 413 SAGN 416 Score = 36.7 bits (83), Expect = 0.033, Method: Composition-based stats. Identities = 47/252 (18%), Positives = 86/252 (34%), Gaps = 37/252 (14%) Query: 398 IKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQG---- 453 +++ L H G +L+R + G + ++ G Sbjct: 673 LQTPTSLFASDYGYHTGALLFRGHFTANGKEKTFFVQTKGGTAYGHSIWINETYVGSWAG 732 Query: 454 --VLERNNVITLNITGKAGAT--LDLLVENMG-RVNYGAYINDFKG----LVSNLTLSSN 504 + + NN T ++G + ++++NMG ++ D K + +L+ Sbjct: 733 TSINDNNNATYTLPTLQSGKNYVITVVIDNMGLDEDWTIGSEDMKNPRGIIQYSLSGQEA 792 Query: 505 ILTDWTIFP----LDTEDAVRSHL--GGWGHRDSGHHDEAWAHNSSNYTLPA-------- 550 W + + D VR L GG G H + + P Sbjct: 793 SAISWKLTGNLGGENYRDTVRGPLNEGGLYAERQGFHQPQPPTQKWDSSSPFTGLTKPGI 852 Query: 551 -FYMGNFSIP-SGIPDLPQDTFIQFPGWT------KGQVWINGFNLGRYWPARGPQLTLF 602 FY +F + D+P + F T + Q+++NG+ G+Y GPQ + Sbjct: 853 RFYSTSFDLDLPSGYDIP--LYFNFGNSTSTPAAYRVQLYVNGYQYGKYVNNIGPQTSFP 910 Query: 603 VPQHILMTSAPN 614 VP+ IL N Sbjct: 911 VPEGILNYHGTN 922 >5GSM-A nrPDB Length = 786 Score = 230 bits (587), Expect = 1e-60, Method: Composition-based stats. Identities = 73/203 (35%), Positives = 107/203 (52%), Gaps = 21/203 (10%) Query: 31 MFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHE 90 M ++++S ++ DG+P G++ + RVP WKDRLLKM+ AGLN + TYV WN+HE Sbjct: 1 MGKVEFSGKRYVIDGEPVTIAGGTLQFFRVPADAWKDRLLKMREAGLNTVDTYVAWNWHE 60 Query: 91 PWPGQYQFSE----DHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESIL 146 P G + F ++ FL LA ELG VI+RPGPYIC EW GG+P WL+++ + Sbjct: 61 PEKGSFDFKGETHPQRNLVGFLELADELGFYVIIRPGPYICGEWRNGGIPDWLIDEHPEI 120 Query: 147 LRSS-----------------DPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEY 189 L P YL AV +W + P ++ LY NGGP+I+V +++E Sbjct: 121 LAKGPNGPLPRDIYYPPITYLHPTYLEAVGEWYNAVFPVIRKYLYTNGGPIISVSIDDEP 180 Query: 190 GSYFACDFDYLRFLQKRFRHHLG 212 + +L + G Sbjct: 181 SYWETIFQPFLTDYNEIITKPGG 203 >5GSL-A nrPDB Length = 778 Score = 224 bits (571), Expect = 9e-59, Method: Composition-based stats. Identities = 78/260 (30%), Positives = 116/260 (44%), Gaps = 46/260 (17%) Query: 33 EIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPW 92 ++ + + D + G++ Y RVPR YW+DRL KMK GLN ++TY+ WN+HEP Sbjct: 5 KVQHDGRLYSLDDERIVVYGGTLQYFRVPRNYWEDRLRKMKSHGLNTVETYIAWNWHEPQ 64 Query: 93 PGQYQFSE----DHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLR 148 G + F+ D+ FL LA +LGL VI+RPGPYIC EW+ GG+P WL+ +L Sbjct: 65 EGVFDFTGETHPQRDLIGFLELAQKLGLYVIIRPGPYICGEWKNGGIPDWLINSHPEILA 124 Query: 149 SS-----------------DPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGS 191 S P YL KW +LP ++ LY NGG +I+V +++E Sbjct: 125 KSPNGSFPRDVYYPPITYLHPTYLEYAMKWYEEVLPIIRDYLYSNGGSIISVTIDDEPSY 184 Query: 192 YFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTG---SNI 248 + +L + G ++LK ++ G Sbjct: 185 WETIFQPFLTDYNEIIVRENGI----------WHSWLK----------ENYSLGDLEERY 224 Query: 249 TDAFLSQRKCEPKGPLINSE 268 + F + P P SE Sbjct: 225 GERFSDYTEIAP--PKSFSE 242 >4D1J-A nrPDB Length = 540 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 42/175 (24%), Positives = 65/175 (37%), Gaps = 25/175 (14%) Query: 37 SRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQY 96 + + + DG P+ + + S KD M+ G N + V W EP GQ+ Sbjct: 12 GKHALMVDGAPYIILGSQTNNSSNYPDALKDVWPSMEKMGANTLSIPVAWEQIEPVEGQF 71 Query: 97 QFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGG---LPAWLL----------EKE 143 FS F+ + + +R A W+ PAW+ +++ Sbjct: 72 DFS-------FVDVLLKEARQRKVRLVLLWFATWKNNAPHYAPAWVKLDNARFPRVVKED 124 Query: 144 SILLRSSDP---DYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFAC 195 L S P + LAA K L+ + VI VQV+NE G+Y A Sbjct: 125 GDTLNSLSPLGQNTLAADKKAFVELMKYLAKR--DKDHTVIMVQVQNEVGTYGAV 177 >4UCF-A nrPDB Length = 689 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 40/189 (21%), Positives = 64/189 (33%), Gaps = 38/189 (20%) Query: 42 LKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVP-WNFHEPWPGQYQFSE 100 LK + + G + + P W D + MK AG+N + + W EP G+Y F Sbjct: 13 LKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDW 72 Query: 101 DHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILL------------- 147 ++ + + G+ V L P WL + +L Sbjct: 73 ---LDRAIDKLGKAGIAVDLASA--------TASPPMWLTQAHPEVLWKDERGDTVWPGA 121 Query: 148 ----RSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGP-VITVQVENEYGSYFACDFDYLRF 202 R + P + + L +M G P V+ V NEYG + FDY Sbjct: 122 REHWRPTSPVFRE----YALNLCRRMAEHY--KGNPYVVAWHVSNEYGCH--NRFDYSDD 173 Query: 203 LQKRFRHHL 211 + F+ Sbjct: 174 AMRAFQKWC 182 >3U7V-A nrPDB Length = 552 Score = 52.1 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 24/175 (13%) Query: 37 SRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKM----KMAGLNAIQTYVPWNFHEPW 92 R + + DG PF ++ ++ W ++ K+ + G N +Q + W EP Sbjct: 47 GRHALMVDGAPFLMLAAQVN----NSSAWPSQMAKVWPAIEKVGANTVQVPIAWEQIEPV 102 Query: 93 PGQYQFSEDHDVEYFLRLAHELGLLVIL-------RPGPYICAEW---EMGGLPAWLLEK 142 GQ+ FS D+ L A E + ++L P EW + P L++ Sbjct: 103 EGQFDFS-YLDL--LLEQARERKVRLVLLWFGTWKNSSPSYAPEWVKLDDKRFPR-LIKD 158 Query: 143 ESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGG--PVITVQVENEYGSYFAC 195 + S P + +D + M L ++ VI VQVENE G+Y + Sbjct: 159 DGERSYSMSPLAKSTLDADRKAFVALMTHLKAKDAAQKTVIMVQVENETGTYGSV 213 >5E9A-A nrPDB Length = 712 Score = 52.1 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 44/172 (25%), Positives = 61/172 (35%), Gaps = 43/172 (25%) Query: 51 ISGSIHYSRVPRFYWKDR-------LLKMKMAGLNAIQTYVP-WNFHEPWPGQYQFSEDH 102 ISG +H + W D + MK A N + + W+ EP G+Y F Sbjct: 36 ISGLLHGADYNPEQWLDHPDVLVRDVEMMKEARCNVMSVGIFSWSALEPEEGRYTFDW-- 93 Query: 103 DVEYFLRLAHELGLLV-ILRPGPYICAEWEMGGLPAWLLEKESILLRS------------ 149 ++ L HE G+ V + P G PAW+ +K +LR Sbjct: 94 -MDQVLNRLHENGISVFLATPS---------GARPAWMSQKYPQVLRVGRDRVPALHGGR 143 Query: 150 -----SDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACD 196 S P Y V G L + Y + VI + NEYG CD Sbjct: 144 HNHCMSSPVYREKVQLMNGQLAKR-----YAHHPAVIGWHISNEYGGECHCD 190 >4OJY-A nrPDB Length = 687 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 34/173 (19%) Query: 62 RFYWKDR-------LLKMKMAGLNAIQTYVP-WNFHEPWPGQYQFSEDHDVEYFLRLAHE 113 W DR L MK++ N V W+ EP G Y+F V F + Sbjct: 24 PDQWLDRPDILQADLELMKLSHTNTFTVGVFAWSALEPEEGVYRFEWLDKV--FDDIYRI 81 Query: 114 LGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSS------------DPDYLAAVDKW 161 G +++ P G PAWL +K +LR + + + ++V + Sbjct: 82 GGRVILATPS---------GARPAWLSQKYPEVLRVNAARVRQLHGGRHNHCFTSSVYRE 132 Query: 162 LGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACD---FDYLRFLQKRFRHHL 211 + ++ Y + ++ V NEYG C+ + +L+K++ H L Sbjct: 133 KTQHINRLLAERYGDHPALLMWHVSNEYGGECHCNLCQEAFREWLKKKYNHDL 185 >3TTS-A nrPDB Length = 675 Score = 45.9 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 47/266 (17%), Positives = 76/266 (28%), Gaps = 46/266 (17%) Query: 47 PFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVP-WNFHEPWPGQYQFSEDHDVE 105 P + G + + + ++ + +AG++ V W + Y F+ D+ Sbjct: 7 PKIWYGGDYNPEQWDKATMEEDMRMFNLAGIDVATVNVFSWAKIQRDEVSYDFTWLDDII 66 Query: 106 YFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLR----------------- 148 RL E Y+C G PAW+ +K +LR Sbjct: 67 E--RLTKEN---------IYLCLATSTGAHPAWMAKKYPDVLRVDYEGRKRKFGGRHNSC 115 Query: 149 SSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFR 208 + P Y G L + K ++ V NEYG Y CD +F + + Sbjct: 116 PNSPTYRKYAKILAGKLAERYKDH-----PQIVMWHVSNEYGGYCYCDNCEKQF-RVWLK 169 Query: 209 HHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVD--------FGTGSNITDAFLSQRKCEP 260 G L + A T V G +N L R+ + Sbjct: 170 ERYGTLEAL---NKAWNTSFWSHTFYDWDEIVAPNALSEEWSGNRTNFQGISLDYRRFQS 226 Query: 261 KGPLINSEFYTGWLDHWGQPHSTIKT 286 L + L W Sbjct: 227 DSLLECFKMERDELKRWTPDIPVTTN 252 >5XB7-A nrPDB Length = 712 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 61/170 (35%), Gaps = 13/170 (7%) Query: 49 RYISGSIHYSRVPRFYWKDRL----LKMKMAGLNAIQT-YVPWNFHEPWPGQYQFSEDHD 103 + + +PR DR+ M AG+N I+ W+ EP PG + ++ Sbjct: 9 ILFGAAYYDEYIPRDL--DRIDTDMEMMTRAGINVIRIGESTWSTCEPQPGHFDWT---H 63 Query: 104 VEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLG 163 ++ L A G+ VI+ Y W + P L + + V+ Sbjct: 64 IDRALDAATNAGINVIVGTPTYAVPTWLVAMYPDVLATTPAGEPHYGARQIMNIVNPAYR 123 Query: 164 VLLPKMKPLLYQNGGP---VITVQVENEYGSYFACDFDYLRFLQKRFRHH 210 + ++ L + VI QV+NE Y + D K+ RH Sbjct: 124 LYGERVIRSLISHVAQQPCVIGYQVDNETKYYDSVSHDMQVMFIKQLRHE 173 >4R27-A nrPDB Length = 434 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 38/269 (14%), Positives = 71/269 (26%), Gaps = 27/269 (10%) Query: 56 HYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELG 115 HY R +++ + + G + + V W EP G + + + L E G Sbjct: 52 HYHR-----YREDIALIAGLGFTSYRFSVEWARIEPEEGHFSVAALDHYKRVLEACREHG 106 Query: 116 LLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQ 175 L ++ + P WLL + + + + L + Sbjct: 107 LTPVVTFHHFAS--------PLWLLRSGGWEGERTPELFARYCGRVMAHLGDLIGVACTL 158 Query: 176 NGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQG 235 N + + G + + + L F C G Sbjct: 159 NEPNLPWLLESFGIGGEAPEN-------RGKVPMWAAAAQRLGVDASTVAPFQFCSTEAG 211 Query: 236 LYTTVDFGTGSNITDAFLSQRK-CEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLY 294 V T+A + R L NS+ + G+ + V Sbjct: 212 F--NVKLAAHKAATEAIKAHRPDLRVGWTLANSDIQS---VPGGEEIAAQVRRDVNERFL 266 Query: 295 DILARGASVNLYMFIGGTNFAYWNGANSP 323 + V + G T + A +P Sbjct: 267 EASRGDDFVGI-QTYGRTVYGPDGHAPAP 294 >5T9G-A nrPDB Length = 846 Score = 35.5 bits (80), Expect = 0.074, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 41/111 (36%), Gaps = 23/111 (20%) Query: 15 LLLLGPTRGLRNATQRMFEIDYS-RDSFLKDGQPFRYISGSIHY------SRVPRFYWKD 67 +L+ G + + I + + F +G+ + +H+ + + W+ Sbjct: 277 ILVDGNVVDTKETPFGIRSIKFDAKKGFFLNGKNMKIKGVCLHHDASMIGAALVEDVWRR 336 Query: 68 RLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLV 118 RL +K G NAI+ H P + FL L E+G LV Sbjct: 337 RLQTLKDGGCNAIRLS-----HNPGA-----------DAFLELCDEMGFLV 371 >1KWK-A nrPDB Length = 645 Score = 35.5 bits (80), Expect = 0.079, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 35/169 (20%) Query: 61 PRFYWKDRLLKMKMAGLNAIQT-YVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVI 119 P+ WK+ +M+ AGL+ ++ W EP PG+ ++ D E LA E +V+ Sbjct: 12 PKERWKEDARRMREAGLSHVRIGEFAWALLEPEPGRLEW-GWLD-EAIATLAAEGLKVVL 69 Query: 120 LRPGPYICAEWEMGGLPAWLLEKESILLRS-----------------SDPDYLAAVDKWL 162 P P WL+++ +L S P Y + + Sbjct: 70 GTP---------TATPPKWLVDRYPEILPVDREGRRRRFGGRRHYCFSSPVYREEARRIV 120 Query: 163 GVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHL 211 +L + L G Q +NEYG + Y Q+ FR L Sbjct: 121 TLLAERYGGLEAVAG-----FQTDNEYGCHDTV-RCYCPRCQEAFRGWL 163 >1OHW-A nrPDB Length = 472 Score = 35.1 bits (79), Expect = 0.098, Method: Composition-based stats. Identities = 27/148 (18%), Positives = 47/148 (31%), Gaps = 9/148 (6%) Query: 129 EWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENE 188 +W + P L+ + A + + L+ K + G +I +++E Sbjct: 214 DWPIAPFPR--LKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAG-IIVEPIQSE 270 Query: 189 YGSYFACDFDYLRFLQKRFRHH-LGDDVVLFTTDGAHKTFLKCGA---LQGLYTTVDFGT 244 G A D D+ R L+ R H V T G L + F + Sbjct: 271 GGDNHASD-DFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTF-S 328 Query: 245 GSNITDAFLSQRKCEPKGPLINSEFYTG 272 +T F + + P P + G Sbjct: 329 KKMMTGGFFHKEEFRPNAPYRIFNTWLG 356 >4W8B-A nrPDB Length = 386 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 91/287 (31%), Gaps = 43/287 (14%) Query: 66 KDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPY 125 + + +K AG +++ W+ H G+ V+ + G+ V+L Sbjct: 40 QQIIDAVKAAGFKSVRIPCSWDIHSDSNGEIDAQWMARVKQVVNYCINDGIYVVL----- 94 Query: 126 ICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQV 185 W+ G W+ E + S Y A + + + ++K L Q+ Sbjct: 95 -NDHWDNG----WI---EVLGFSKSSSSYQAVDEATITSKITRLKDLW---------TQI 137 Query: 186 ENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTG 245 NE+ DY L + + LF+ T + C Q V G Sbjct: 138 ANEF-------KDYDEHLLFAGLNEPFQEYSLFSGHHEELTPILCRYNQAFVEAVRATGG 190 Query: 246 SNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDI--LARGASV 303 +N QR +GP N ++ + E + ++ G Sbjct: 191 NNA------QRTLVVQGPSTNINSSVNYMT------ADKLPETAGRLMVEVHYYDPGQFC 238 Query: 304 NLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFAL 350 + G F +W AN T + LS+ G L Y +L Sbjct: 239 GTFDASGDNAFYFWGAANHSTDHNATYGEEAYMLSQFGLLKTAYTSL 285 >6HA9-A nrPDB Length = 396 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 32/223 (14%), Positives = 70/223 (31%), Gaps = 35/223 (15%) Query: 67 DRLLKMKMAGLNAIQTYVPWNFHEPWP-GQYQFSEDHDVEYFLRLAHELGLLVILRPGPY 125 + L +K +G +A++ V W+ + + + + V+ +++A + L V+ Sbjct: 79 ELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVL------ 132 Query: 126 ICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPL---LYQNGGPVIT 182 I W+ G WL + +I D + + + ++ L G Sbjct: 133 INIHWDGG----WL--ENNITPAKKDENNAKQ-KAFWEQIATHLRDFDEHLLFAGTN--- 182 Query: 183 VQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDF 242 E YL+ R G + ++ + G + + T + Sbjct: 183 -APNAENAEQMDVLNSYLQTFVDAVRSTGGKNA--------YRVLVLQGPVTDIEKTNEL 233 Query: 243 GTGSNITDAFLSQ-RKCEPKGPLINS-----EFYTGWLDHWGQ 279 T A + P + E + +WG+ Sbjct: 234 WTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGE 276 >5DT5-A nrPDB Length = 471 Score = 34.0 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 49/136 (36%), Gaps = 16/136 (11%) Query: 44 DGQPFRYISGSI---HYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSE 100 DG+ F +G + HY R +++ + +K G++ + + W P GQ+ Sbjct: 62 DGKVFEKHNGDVACDHYHR-----FEEDIQHIKQLGVDTYRFSIAWPRIFPSKGQFNPEG 116 Query: 101 DHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDK 160 + E G ++P + W+ LP W E+ + R S +L Sbjct: 117 MAFYKTLATRLQEEG----IKPAVTL-YHWD---LPMWAHEEGGWVNRDSVDWFLDFARV 168 Query: 161 WLGVLLPKMKPLLYQN 176 L + + N Sbjct: 169 CFEELDGIVDSWITHN 184 >2OC2-A nrPDB Length = 591 Score = 33.6 bits (75), Expect = 0.29, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 58/167 (34%), Gaps = 28/167 (16%) Query: 20 PTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNA 79 P+ + T+ M + ++ K+ F G + VP +W +L+ G Sbjct: 258 PSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLP---VPPEFWNKSMLEKPTDGREV 314 Query: 80 IQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWL 139 + W+F+ + + ++E + A EMG + ++ Sbjct: 315 VCHASAWDFYNGKDFRIKQCTTVNLEDL------------------VVAHHEMGHIQYFM 356 Query: 140 LEKE-SILLRSS-DPDYLAAVDKWLGVLLPKMK-----PLLYQNGGP 179 K+ + LR +P + A+ L + + K LL GG Sbjct: 357 QYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS 403 >3VDH-A nrPDB Length = 353 Score = 32.8 bits (73), Expect = 0.53, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 22/59 (37%) Query: 62 RFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL 120 +D + + G NA++ V W H G + V+ + A GL I+ Sbjct: 51 PETTQDMMTFLMQNGFNAVRIPVTWYEHMDAEGNVDEAWMMRVKAIVEYAMNAGLYAIV 109 >5J7Z-A nrPDB Length = 500 Score = 32.4 bits (72), Expect = 0.62, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 26/73 (35%), Gaps = 5/73 (6%) Query: 75 AGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL---RPGPYICAEWE 131 G N ++ ++ P GQ + + + G+ V+L + G + W Sbjct: 91 HGFNTVRLGTSFDALMPQRGQIDEAYLDRLTGVVDALTARGMHVLLDNHQDG--LSKAWG 148 Query: 132 MGGLPAWLLEKES 144 G P W +E Sbjct: 149 GNGFPEWAIESRP 161 >5T99-A nrPDB Length = 822 Score = 32.4 bits (72), Expect = 0.70, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 22/96 (22%) Query: 30 RMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYW------KDRLLKMKMAGLNAIQTY 83 + +I +++D F +G+ R+ +H+ P + +L MK G+NAI+T Sbjct: 289 GIRKICFTKDGFFLNGEKIRFNGVCLHHDNGPMGAAVNVRADERKLQIMKEMGVNAIRTS 348 Query: 84 VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVI 119 H P + FL L +GL+V+ Sbjct: 349 -----HNPPSPE-----------FLDLCDRMGLVVL 368 >4R30-A nrPDB Length = 184 Score = 32.0 bits (71), Expect = 0.77, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 52/141 (36%), Gaps = 11/141 (7%) Query: 54 SIHYSRVPRFYW--------KDRLLKMK-MAGLNAI-QTYVPWNFHEPWPGQYQFSEDHD 103 ++HYSR+ W + +K+K G+ A+ W+ + G ++ E Sbjct: 7 AMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMT 66 Query: 104 VEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLG 163 + ++L E GL I P P + E + LP + ++ L Y+ + Sbjct: 67 PDTMIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHAL-LEKGHIVYVHSNAGVGR 125 Query: 164 VLLPKMKPLLYQNGGPVITVQ 184 L Y G + VQ Sbjct: 126 STAAVCGWLQYVMGWNLRKVQ 146 >3NDZ-A nrPDB Length = 345 Score = 32.0 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 24/54 (44%), Gaps = 2/54 (3%) Query: 69 LLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSED--HDVEYFLRLAHELGLLVIL 120 + K+K AG N ++ V W+ H +Y + VE A + + VI+ Sbjct: 48 INKIKEAGFNTLRLPVTWDGHMGAAPEYTIDQTWMKRVEEIANYAFDNDMYVII 101 >1D9K-B nrPDB Length = 112 Score = 32.0 bits (71), Expect = 0.91, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 25/57 (43%) Query: 313 NFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPST 369 N YW ++ + + Y Y A +E GD+ + Y A R + F + E P T Sbjct: 28 NNMYWYRQDTGHGLRLIHYSYGAGSTEKGDIPDGYKASRPSQENFSLILELATPSQT 84 >1VFF-A nrPDB Length = 423 Score = 32.0 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 36/107 (33%), Gaps = 13/107 (12%) Query: 63 FYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRP 122 ++D + M G NA + + W+ P ++ + L G+ ++ Sbjct: 50 ELYRDDIQLMTSLGYNAYRFSIEWSRLFPEENKFNEDAFMKYREIIDLLLTRGITPLVTL 109 Query: 123 GPYICAEWEMGGLPAWLLEKESILLRSSD----PDYLAAVDKWLGVL 165 + P W ++K LR + Y+ V + L + Sbjct: 110 HHFTS--------PLWFMKKGGF-LREENLKHWEKYIEKVAELLEKV 147 >3GM8-A nrPDB Length = 801 Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 33/91 (36%), Gaps = 7/91 (7%) Query: 531 DSGHHDEAWAHNSSNYTLPA---FYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFN 587 + + + + LPA +Y F+IPS + + + +VWING Sbjct: 46 EGTYKQFENGTDWQSGFLPAGISWYRKTFTIPSKWKNKKVQILFE-GVYLNSEVWINGHW 104 Query: 588 LGRYWPARGPQLTLFVPQHILMTSAPNTITV 618 LG+ G ++ + N I V Sbjct: 105 LGK--RPNGYISFVYDLTP-YLQEGKNQIAV 132 >4NHU-B nrPDB Length = 254 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 25/57 (43%) Query: 313 NFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPST 369 N YW ++ + + Y Y A +E GD+ + Y A R + F + E P T Sbjct: 34 NNMYWYRQDTGHGLRLIHYSYGAGSTEKGDIPDGYKASRPSQENFSLILELATPSQT 90 >1OTJ-A nrPDB Length = 283 Score = 31.3 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%) Query: 611 SAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGS 646 + I VL+ +D VTF++ P G+ Sbjct: 77 EGVDEIIVLDTHNDNPPDNDNWHTDVTFIETPPAGA 112 >4RKK-A nrPDB Length = 332 Score = 31.3 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 52/141 (36%), Gaps = 11/141 (7%) Query: 54 SIHYSRVPRFYW--------KDRLLKMK-MAGLNAI-QTYVPWNFHEPWPGQYQFSEDHD 103 ++HYSR+ W + +K+K G+ A+ W+ + G ++ E Sbjct: 157 AMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMT 216 Query: 104 VEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLG 163 + ++L E GL I P P + E + LP + ++ L Y+ + Sbjct: 217 PDTMIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHAL-LEKGHIVYVHSNAGVGR 275 Query: 164 VLLPKMKPLLYQNGGPVITVQ 184 L Y G + VQ Sbjct: 276 STAAVCGWLQYVMGWNLRKVQ 296 >1VA6-A nrPDB Length = 518 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 31/96 (32%), Gaps = 9/96 (9%) Query: 385 VGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDC-----SNPAPLSSPLNGV 439 + A + S L F + + ++ Y T+L + + L N + Sbjct: 197 LFGASPAISSSFLQGKPTSLPFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDL 256 Query: 440 HDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDL 475 ++ V G+ Q + + K G L + Sbjct: 257 YE----YVAGLKQAIKTPSEEYAKIGIEKDGKRLQI 288 >2OYK-A nrPDB Length = 481 Score = 29.7 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 29/85 (34%), Gaps = 9/85 (10%) Query: 35 DYSRDSFLKDGQPFRYISGSIHYSRVPRFYWK-DRLLKMKMAGLNAIQTYVPWNFHEPWP 93 D S + G F S + + + D + G N ++ + W EP P Sbjct: 39 DDDGRSLILRG--FNTASSAKSAPDGMPQFTEADLAREYADMGTNFVRFLISWRSVEPAP 96 Query: 94 GQYQFSEDHDVEYFLRLAHELGLLV 118 G Y D +Y R+ +G Sbjct: 97 GVY------DQQYLDRVEDRVGWYA 115 >4HZ6-A nrPDB Length = 444 Score = 29.3 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 56/159 (35%), Gaps = 19/159 (11%) Query: 29 QRMFEIDYSRDSFLKDGQPFRYISGSI---HYSRVPRFYWKDRLLKMKMAGLNAIQTYVP 85 E + R + G+ SG + HY R ++ L M+ GL + + Sbjct: 27 DGKGESIWDRFT-RIPGKIKNGDSGDVACDHYHR-----YEQDLDLMRQLGLKTYRFSIA 80 Query: 86 WNFHEPWPGQYQFSEDHDV-EYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKES 144 W +P + D + H+ +L + W+ LP W+ ++ Sbjct: 81 WARIQPDSSRQINQRGLDFYRRLVEGLHKRDILPMA-----TLYHWD---LPQWVEDEGG 132 Query: 145 ILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITV 183 L R S + + L ++ PL + P++TV Sbjct: 133 WLSRESASRFAEYTHALVAALGDQI-PLWVTHNEPMVTV 170 >5G56-A nrPDB Length = 862 Score = 29.3 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 36/87 (41%), Gaps = 9/87 (10%) Query: 43 KDGQPFRYISGSIHYSRVP--RFYW-----KDRLLKMKMAGLNAIQTYVP-WNFHEPWPG 94 + ++ + R P W D++ ++K G NA+ Y ++ P PG Sbjct: 10 LNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPG 69 Query: 95 -QYQFSEDHDVEYFLRLAHELGLLVIL 120 + ++++ + ELGL +++ Sbjct: 70 SKAPGYAVNEIDKIVERTRELGLYLVI 96 >4OVQ-A nrPDB Length = 325 Score = 29.3 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 19/46 (41%), Gaps = 2/46 (4%) Query: 267 SEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGT 312 + + GW H +T+ + A L + G L MF GGT Sbjct: 23 MDNWRGWNIHVDGYPNTVAMDKFAELLA--VKTGGEYTLQMFHGGT 66 >5LA1-A nrPDB Length = 491 Score = 28.9 bits (63), Expect = 6.4, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 36/87 (41%), Gaps = 9/87 (10%) Query: 43 KDGQPFRYISGSIHYSRVP--RFYW-----KDRLLKMKMAGLNAIQTYVP-WNFHEPWPG 94 + ++ + R P W D++ ++K G NA+ Y ++ P PG Sbjct: 12 LNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPG 71 Query: 95 -QYQFSEDHDVEYFLRLAHELGLLVIL 120 + ++++ + ELGL +++ Sbjct: 72 SKAPGYAVNEIDKIVERTRELGLYLVI 98 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.127 0.351 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,580,861 Number of Sequences: 36641 Number of extensions: 1094545 Number of successful extensions: 2962 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 2799 Number of HSP's gapped (non-prelim): 91 length of query: 677 length of database: 10,336,785 effective HSP length: 104 effective length of query: 573 effective length of database: 6,526,121 effective search space: 3739467333 effective search space used: 3739467333 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)